LOCUS       DAMEEU010000001       116200 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.001, whole genome shotgun sequence.
ACCESSION   DAMEEU010000001 DAMEEU010000000
VERSION     DAMEEU010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 116200)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 116200)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..116200
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.001"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(33..1076)
                     /locus_tag="PB779_000001"
     CDS             complement(33..1076)
                     /locus_tag="PB779_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0737560.1"
                     /translation="MKKILVSLLFLVSLVTLVGCSQSQGEKQSEKEKSKIALVLGFGG
                     VDDRSFNQAGWEGLEAWGKEKKLTAKKDFTYIETNNPEDNSTNIDQAIRNGFTTIISL
                     SYLQAEELENAAKDNPKLKFALVDGEITGKKNISSATFKDQESAYLAGLAAAYTTKSD
                     QVGFIGGMEGPVIQRFQSGFEAGVKAGATALNKEITVNVQYAASYDSLDKGKAIAASM
                     YKEGVDILYQAAGSTGAGVFQEAKARNENDYSRKVWVIGVDRDQADEGDYKMENGETG
                     NFTLTSTKKNVGAEVKEFAETSHNDKFPGGKHLTFGLKEEGVDLTKGQLSEEAYQAVS
                     DAKEKIISGDFRL"
     gene            complement(1237..1920)
                     /locus_tag="PB779_000002"
     CDS             complement(1237..1920)
                     /locus_tag="PB779_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic nucleotide-binding domain-containing
                     protein"
                     /protein_id="HDE0737561.1"
                     /translation="MKKIHDTKQLTAYVEKHNLQDYMDSDILAMASLLFFEKEEHLIQ
                     TGKTSDYLYFLVDGTVMVYSYSSDTQNICIDYAKPATPLGEASSLWELSPKSSVKAVT
                     KCICISIPLNQYRTQLQKDVRFLQNICQLLSYRLNSGINLANSLTEPVETRLAKFILT
                     HHENERFSFRLTTCASILNVSYRHLLRTITNFREENIIEKKKNYYLIHDIEALEDLAE
                     NISSPVKAE"
     gene            2115..3044
                     /locus_tag="PB779_000003"
     CDS             2115..3044
                     /locus_tag="PB779_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate/phosphite/phosphonate ABC transporter
                     substrate-binding protein"
                     /protein_id="HDE0737562.1"
                     /translation="MQFKQLAKGFIGVMLLTTLAACGSGNTSSSSEKESKEKLVVQFV
                     PTNNDGSMEAKAKPFAKYLSKKLDREVEVTLATDYSTIVEAMSSGQVDVGIMPPAAYV
                     QAKDAGAADAILTSQLGDYDQETGLPLKDKLTNTFKGEVLVRADSGLNKLTDLKGKNI
                     ATLSPNSASGYIYPVAELKDAGIDPTADTKMTTVNDIPSEITAVLNKQMDAAFVFEGA
                     RNVFASNFPDNDLFKDLKVLYLTKGDIPNDAIAVQPDMSKDLKAKIKETFLNMKDDKD
                     GKEAMALWGHQGYEEAADSAYDTIRDYTKKAAE"
     gene            3105..3896
                     /gene="phnC"
                     /locus_tag="PB779_000004"
     CDS             3105..3896
                     /gene="phnC"
                     /locus_tag="PB779_000004"
                     /EC_number="7.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HDE0737563.1"
                     /translation="MIIFDNVSKVYPNGVVGLKDIDLTIEDGEFVSIIGLSGAGKSTL
                     LRSINRLAETTKGDIRINGTSITKANKKELRQIRRQIGLISQSFNLVKRSTVQKNVLS
                     GRLGYYSTWKSILGLFTKEDYQQTKEALEKVGLSDKLQTRSDELSGGQQQRVSIARAL
                     VQQAPIILADEPVASLDPITTQKVMMDLKNINQTMDKTVIVNLHSVPLAREFSTRVLA
                     LKAAQVVFDGRPDDLTDERLEQIYGNAIFEEKAGEIDELERNRSL"
     gene            3868..4647
                     /gene="phnE"
                     /locus_tag="PB779_000005"
     CDS             3868..4647
                     /gene="phnE"
                     /locus_tag="PB779_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010743453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDE0737564.1"
                     /translation="MSLKETVHFKWYKHLLILLFLIVCFQGSAWITSADFSQVFQNSN
                     QMTVFLSRFIHPDFSYLPKLVEPMVKTLQMSLLGTVIGLILAIPVSFLATTVVTENRL
                     LSTIFRFLLGLVRTIPTLLLAALFVAVFGIGEATGVLTIAVFTFGMVSQLMFQAIETI
                     DFGPIEAAAAVGANKMQIAIWSIAPQVLSQFASYAFYAFEVNVRASTVLGYVGAGGIG
                     VILNSSLALLNYERVSIIILTILVTVAIVDKLSERVRRSLL"
     gene            4644..5426
                     /gene="phnE"
                     /locus_tag="PB779_000006"
     CDS             4644..5426
                     /gene="phnE"
                     /locus_tag="PB779_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005233297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HDE0737565.1"
                     /translation="MMLREMNRRTLLSLVALVILVILSAATLDYSGLSTFSPSMGMDV
                     LRGLGQPDWQFLYDGSGEDLISLLLLTIGIACLGTMIATVLAIPITLISAVNLWQAHP
                     WVTKIGKLICNVLRAFPELVFAIIFVKVVGPGPFAGVMAIGVHQIGMLGKLFTEEMEA
                     MDERLVEEMHAVGANFWQTIFFVRIPYLMPIYCSLALNHFEIAVRSAATLGLVGAGGI
                     GAPLIFAIQTRSWSKVSIILIGVVVTVFILDQITGIIRKRLR"
     gene            5429..6232
                     /locus_tag="PB779_000007"
     CDS             5429..6232
                     /locus_tag="PB779_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDE0737566.1"
                     /translation="MNILHISDIHFRREYEACEEGYKGMLATMQNPLIPLEQCIHHLL
                     QQTPLDLVIISGDLTEDGEIDDYRYLKTWLENALGETTILVTLGNHDIKEHFWVGWCD
                     EAASSAPYNQIVKYPEFTVISFDNSSYGYADGIVDDQQFQWLKKALEQEKDQPIFLVT
                     HHHLLSHQSSIPKWPGTERFLKLIAPYDIRCILNGHTHHTFTDEINGIPYFTVSSMSF
                     VGEDEGDGFVRFEERHGYNLYHLDQGRIVRQTTENFIPGNILKTLQMKD"
     gene            6316..7863
                     /locus_tag="PB779_000008"
     CDS             6316..7863
                     /locus_tag="PB779_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HDE0737567.1"
                     /translation="MNITFLETSDMHGYVSPTDYSGRTDLALGTAKVSSKLKELRAKA
                     DGPVITIENGDFIQGSPLSYYLAKEYGSAKELTDLINQMSYDVQVLGNHEFNYGVDYL
                     EEAIKNYQAPILGANMVNKNDQPYFGNAYKIIEKVGVKIAILGLTTQYIPHWEKPETL
                     AGITFKSIVETAKEYVPLLRKQADLVIVSYHGGFEKDLLTGEDTEALTGENEGYELLQ
                     QVEGIDALFTGHQHRKIAETVHGVPVVQPGYRGEFIGEIRLTVEKKEGQVVVTDHQVA
                     LHSVEKSEPDPEILAAIVPVEEKLEKWLDQPLGKVNGNMRINDPMQARLEEHPYVEFI
                     NRVQLFASGSEISGTALFNNEGKGFGETITMRDVITNYIYPNTLAVIQINGADLRAAL
                     EQTANYLAVENNQIVFNPAFIQPKPQYYNYDMYEGIQYTIDMKQPVGQRITELRFKGH
                     PVLPQQMLEVVTNQYRAIGGGNYAMFGAEKIVREIQIDMTELIADYLNIHPRIEAKVN
                     HNFQVIL"
     gene            complement(8160..8357)
                     /locus_tag="PB779_000009"
     CDS             complement(8160..8357)
                     /locus_tag="PB779_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737568.1"
                     /translation="MVECLKNKKMEANFVKAVISGSIVFQEEYRDMEKDFSKKGIELI
                     DYPRSCPILDKEYPEILTTFF"
     gene            complement(8433..8633)
                     /locus_tag="PB779_000010"
     CDS             complement(8433..8633)
                     /locus_tag="PB779_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDE0737569.1"
                     /translation="MIEEEQKNIWDRYYKADPSSKNTKIGESGLGLSIVKELVRLHHG
                     SIEVTSRKNEGTTFLIQFPKEK"
     gene            complement(8753..9940)
                     /locus_tag="PB779_000011"
                     /pseudo
     CDS             complement(8753..9940)
                     /locus_tag="PB779_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(9985..11111)
                     /locus_tag="PB779_000012"
     CDS             complement(join(9985..10883,10883..11111))
                     /locus_tag="PB779_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611172.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDE0737570.1"
                     /translation="MTRYEENFKQMIVELNQTGRSVRGLAKEYGLSEATIYKWKNLYL
                     PDQSTGLTGKEVAELRKENARLNEELEILKKAGSHILSENLNSLVQFIEKWCKDYTVS
                     LLCRLLEIPRSVYYFYKNKPLTATEIRNNKLKKKISTIFFTNKQRYGATKIHQVLLKE
                     GISVSLKHVQKLMKQLNLRSIVVKKYRPQRSNKPIISKENLLNQDFSTETICEKWAAD
                     ITYIPTKKNGWCYLSSIMDLHTKKIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMIL
                     HTDLGSQYTAREVEQWLKTNKIRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDF
                     EEANRALFSYIEGFYNRNRIHSSIHYLTPQEFEELAKEKMA"
     gene            complement(11515..12297)
                     /locus_tag="PB779_000013"
     CDS             complement(11515..12297)
                     /locus_tag="PB779_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737571.1"
                     /translation="MENSSNSAEVNVSTSTSEVVKCSQETTSLPEELLGDWQINNKDA
                     GIEISDSKAVFRIGRSQVESKDYYVDVNNKMLLHVYFSFEYDSVKYIEVSIERTGYSE
                     FISKSVGILTMHTKDGQYISLGVKRVSGENNETEAVTEQTMDERIDSSKSNETEVDTG
                     KTIDERIDSFIETYTAIPPTWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNA
                     VTEQVGKDIPLRLLENGKKDYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(12362..13198)
                     /locus_tag="PB779_000014"
     CDS             complement(12362..13198)
                     /locus_tag="PB779_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDE0737572.1"
                     /translation="MRVIKTLNNSLILCLDKQGKEVILMGKGIGFQLKKGDLVPADKI
                     QKVFKLDSLSDALKKDYIKLFEAAPDDLIICVKRIIDYANAKFDFKLNKSLFFTLVDH
                     LKHAIERSQKGIVFQNRLLIEIQKYYPKEFEIGCYAIQLINKKMNVQLPEEEAGNIAF
                     HIVNAQSEQANMEETMLSVRALKDILAMLGYLFPEKKVDKDSMLYLRFVTHLQFFIAR
                     MIKKEELPEKDDFLLASVKQRFPKEYRAALKIKEYVQEEMGASANQDELLYLTLHISR
                     VY"
     gene            complement(13216..14625)
                     /locus_tag="PB779_000015"
     CDS             complement(13216..14625)
                     /locus_tag="PB779_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010757186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0737573.1"
                     /translation="MQYKQLSAFPEKFLWGASISAYQAEGAYQEDGKQPSIIDKYQHT
                     EGVANFEVASDFYHHYKEDIQLFKELGLKAFRFSIAWTRIMDIENNKTNQKGISFYHQ
                     VIDECLNQGIEPIVTMYHFDLPYFLEEQGGWLNRATIDYFVDYVQVLLTEYGDKVNYW
                     LTINEQNTMILHPGAIGLPPSGELPSKKELFQINHHVLLAQARVIHLYHQLNLKGKIG
                     PAINLTAMYQATSSPEDAIAAHNWETLRGWSFLDVAVRGKYNYLFENYLNDRGLYPKI
                     EAEDQAILSSGKPDFIAINYYSTATIAASKNDGSDVSARAGDQQIMLGEEGVYRAAEN
                     PYVDKTPYGWVVDPTGLRLTLRKLYDRYDLPILITENGYGAPDIVEEDRRINDQDRID
                     YLAKHILAIQAALTDGVDVFGYLPWSAIDVVSTHQGFNKRYGFIYVDRTDENLKELKR
                     IKKESFFWYQKVIARNGLA"
     gene            complement(14639..16462)
                     /locus_tag="PB779_000016"
     CDS             complement(14639..16462)
                     /locus_tag="PB779_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0737574.1"
                     /translation="MDYREVGRNVLQQVGGKENVVSLTHCATRLRFELKDKRKADTKA
                     LEKTLGVISVVDSGGQYQVVIGNEVQTAFKEIQKEVGTSIKKGPSSDNQESIISRLIS
                     VISTTFTPMIPAITGAGMVKAILAVLTLTGVLSDSSQTYIILNTIADAAFYFMPVLLA
                     YGAAIKFDVNPILAITVAGILLHPNISQLFSTGDAVSFLGIPVLAADYAGSVLPIIFT
                     VWIMSYVEPFADRISPSFIKFFTKPMLVFLIMGPLALVVIGPFGTLLNDLIAMGAEWI
                     NGKAAWLIPFLMGGLQPFLVVTGTAWAMTPIATMQLSSTGSEMINGPGMLASNIAQSG
                     ATFAVAAKTKNKELKQLAVSTGITALMGITEPSLYGVTLKLKKPLVASMIGGAIAGLY
                     AGLSGLVRYAFVSPGLAALPAFIGENPMNIVHAIITCVIAFVATFIIAYLIGFDDTSD
                     ESEQTAIAEAVIVENPVKGTVCPISEVNDAVFSKGLLGKGVAIHPEENSIYSPVEGEV
                     ITILESKHAIGLRSKEGIELLIHVGIDTVNLKGEPFEVFVKAGDQVSAGQLLINADFA
                     AIRNAGYDDTVIVVVTNSENYAGISEASGSLKEHEPLMQIS"
     gene            complement(17305..17631)
                     /locus_tag="PB779_000017"
     CDS             complement(17305..17631)
                     /locus_tag="PB779_000017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737575.1"
                     /translation="MNKVNMNKKFIIIVIVVLAIIGIIFSKMTGTSGLEKSSKPLVTQ
                     ILQEQYNLNRSCDDVTITHENGDNTYRAKAILDNGSAININIEYYPKKDRIYVEIPYA
                     EVLMLN"
     gene            complement(17677..18039)
                     /locus_tag="PB779_000018"
     CDS             complement(17677..18039)
                     /locus_tag="PB779_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010717431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HDE0737576.1"
                     /translation="MYCRKCGKEITDESKYCQFCGALQETDETTGADAVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVALAFIPVVFGAVAVIMGYLYRDKDEQMGTILM
                     IAGVAGAIFGVLLGMSMY"
     gene            complement(18076..18290)
                     /locus_tag="PB779_000019"
                     /pseudo
     CDS             complement(18076..18290)
                     /locus_tag="PB779_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            18418..18753
                     /locus_tag="PB779_000020"
     CDS             18418..18753
                     /locus_tag="PB779_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0737577.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAEKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVVVDYEEEFLALYRSLSTEDAVRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(18829..20826)
                     /locus_tag="PB779_000021"
     CDS             complement(18829..20826)
                     /locus_tag="PB779_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737578.1"
                     /translation="METSMINIPIYVDKEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSFYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFNHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELTNTVC
                     ERLRNVGNNSVENALKENRGYFVKQGFTLERASKDIKRLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPLYQFTSVTRDDGRRVRKRKDPIVLN"
     gene            complement(20924..21199)
                     /locus_tag="PB779_000022"
     CDS             complement(20924..21199)
                     /locus_tag="PB779_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0737579.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            21431..22165
                     /locus_tag="PB779_000023"
     CDS             21431..22165
                     /locus_tag="PB779_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0737580.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            22204..23346
                     /locus_tag="PB779_000024"
     CDS             22204..23346
                     /locus_tag="PB779_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0737581.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(23441..24832)
                     /gene="sufB"
                     /locus_tag="PB779_000025"
     CDS             complement(23441..24832)
                     /gene="sufB"
                     /locus_tag="PB779_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HDE0737582.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(24837..25307)
                     /locus_tag="PB779_000026"
     CDS             complement(24837..25307)
                     /locus_tag="PB779_000026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HDE0737583.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(25294..26529)
                     /locus_tag="PB779_000027"
     CDS             complement(25294..26529)
                     /locus_tag="PB779_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDE0737584.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(26526..27812)
                     /gene="sufD"
                     /locus_tag="PB779_000028"
     CDS             complement(26526..27812)
                     /gene="sufD"
                     /locus_tag="PB779_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HDE0737585.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(27825..28598)
                     /gene="sufC"
                     /locus_tag="PB779_000029"
     CDS             complement(27825..28598)
                     /gene="sufC"
                     /locus_tag="PB779_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HDE0737586.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(28795..29643)
                     /locus_tag="PB779_000030"
     CDS             complement(28795..29643)
                     /locus_tag="PB779_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDE0737587.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(29667..30353)
                     /locus_tag="PB779_000031"
     CDS             complement(29667..30353)
                     /locus_tag="PB779_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0737588.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(30346..31380)
                     /locus_tag="PB779_000032"
     CDS             complement(30346..31380)
                     /locus_tag="PB779_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0737589.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(31443..31699)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(31775..32113)
                     /locus_tag="PB779_000033"
     CDS             complement(31775..32113)
                     /locus_tag="PB779_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HDE0737590.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(32115..32471)
                     /locus_tag="PB779_000034"
     CDS             complement(32115..32471)
                     /locus_tag="PB779_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HDE0737591.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(32477..33664)
                     /locus_tag="PB779_000035"
     CDS             complement(32477..33664)
                     /locus_tag="PB779_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDE0737592.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(33855..34700)
                     /locus_tag="PB779_000036"
     CDS             complement(33855..34700)
                     /locus_tag="PB779_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0737593.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            34934..35899
                     /locus_tag="PB779_000037"
     CDS             34934..35899
                     /locus_tag="PB779_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HDE0737594.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            36276..37319
                     /locus_tag="PB779_000038"
     CDS             36276..37319
                     /locus_tag="PB779_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HDE0737595.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(37381..37845)
                     /locus_tag="PB779_000039"
     CDS             complement(37381..37845)
                     /locus_tag="PB779_000039"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HDE0737596.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            38091..39038
                     /locus_tag="PB779_000040"
     CDS             38091..39038
                     /locus_tag="PB779_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDE0737597.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(39249..41321)
                     /locus_tag="PB779_000041"
     CDS             complement(39249..41321)
                     /locus_tag="PB779_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDE0737598.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(41254..41631)
                     /locus_tag="PB779_000042"
     CDS             complement(41254..41631)
                     /locus_tag="PB779_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HDE0737599.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(41760..42338)
                     /locus_tag="PB779_000043"
     CDS             complement(41760..42338)
                     /locus_tag="PB779_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0737600.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            42470..43762
                     /locus_tag="PB779_000044"
     CDS             42470..43762
                     /locus_tag="PB779_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDE0737601.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(43822..44940)
                     /locus_tag="PB779_000045"
     CDS             complement(43822..44940)
                     /locus_tag="PB779_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HDE0737602.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(44954..46375)
                     /gene="arcD"
                     /locus_tag="PB779_000046"
     CDS             complement(44954..46375)
                     /gene="arcD"
                     /locus_tag="PB779_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HDE0737603.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(46621..47742)
                     /gene="mnmA"
                     /locus_tag="PB779_000047"
     CDS             complement(46621..47742)
                     /gene="mnmA"
                     /locus_tag="PB779_000047"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HDE0737604.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            48146..48745
                     /locus_tag="PB779_000048"
     CDS             48146..48745
                     /locus_tag="PB779_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HDE0737605.1"
                     /translation="MNYFISDMHFFHERLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(48883..50169)
                     /gene="efmA"
                     /locus_tag="PB779_000049"
     CDS             complement(48883..50169)
                     /gene="efmA"
                     /locus_tag="PB779_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HDE0737606.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(50440..50784)
                     /locus_tag="PB779_000050"
     CDS             complement(50440..50784)
                     /locus_tag="PB779_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HDE0737607.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(50921..52066)
                     /locus_tag="PB779_000051"
     CDS             complement(50921..52066)
                     /locus_tag="PB779_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDE0737608.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(52246..53220)
                     /locus_tag="PB779_000052"
     CDS             complement(52246..53220)
                     /locus_tag="PB779_000052"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDE0737609.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(53300..54175)
                     /locus_tag="PB779_000053"
     CDS             complement(53300..54175)
                     /locus_tag="PB779_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HDE0737610.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            54305..56212
                     /locus_tag="PB779_000054"
     CDS             54305..56212
                     /locus_tag="PB779_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HDE0737611.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(56753..60031)
                     /locus_tag="PB779_000055"
     CDS             complement(56753..60031)
                     /locus_tag="PB779_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HDE0737612.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPGNDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(60302..60847)
                     /locus_tag="PB779_000056"
     CDS             complement(60302..60847)
                     /locus_tag="PB779_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDE0737613.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDSVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(60859..61551)
                     /locus_tag="PB779_000057"
     CDS             complement(60859..61551)
                     /locus_tag="PB779_000057"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HDE0737614.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(61570..61854)
                     /locus_tag="PB779_000058"
     CDS             complement(61570..61854)
                     /locus_tag="PB779_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737615.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(61867..62429)
                     /locus_tag="PB779_000059"
                     /pseudo
     CDS             complement(61867..62429)
                     /locus_tag="PB779_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
     gene            62657..63319
                     /locus_tag="PB779_000060"
     CDS             62657..63319
                     /locus_tag="PB779_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HDE0737616.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            63443..64639
                     /locus_tag="PB779_000061"
     CDS             63443..64639
                     /locus_tag="PB779_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HDE0737617.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(64740..66116)
                     /locus_tag="PB779_000062"
     CDS             complement(64740..66116)
                     /locus_tag="PB779_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0737618.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(66153..67019)
                     /locus_tag="PB779_000063"
     CDS             complement(66153..67019)
                     /locus_tag="PB779_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HDE0737619.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(67108..68133)
                     /locus_tag="PB779_000064"
     CDS             complement(67108..68133)
                     /locus_tag="PB779_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDE0737620.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(68151..68825)
                     /locus_tag="PB779_000065"
     CDS             complement(68151..68825)
                     /locus_tag="PB779_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0737621.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(69009..69902)
                     /locus_tag="PB779_000066"
     CDS             complement(69009..69902)
                     /locus_tag="PB779_000066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDE0737622.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(69976..71673)
                     /locus_tag="PB779_000067"
     CDS             complement(69976..71673)
                     /locus_tag="PB779_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDE0737623.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(71666..72979)
                     /locus_tag="PB779_000068"
     CDS             complement(71666..72979)
                     /locus_tag="PB779_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDE0737624.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(72979..77016)
                     /locus_tag="PB779_000069"
     CDS             complement(72979..77016)
                     /locus_tag="PB779_000069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDE0737625.1"
                     /translation="MVVDERIDNQELQENETDTEDSAEIQRSEENEMEKLDEPIVPSG
                     QALQRIQRQLFNGILERLGPTATQDPYEYIYPSGEVENEQHRYPKFTTNDYTKVLGNW
                     TQSNERYQGDKGSPYDGENLIDDSDYTNGGANWRNYDYATNNGSTAGEEDRNVPAQTV
                     QLWGNERNFENSYLDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEKK
                     EISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMVN
                     FYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETLY
                     KDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDVL
                     FRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGSS
                     NNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAIG
                     RNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVSP
                     FGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYKF
                     SPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSSS
                     IRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFETK
                     MPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEYT
                     SGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNIN
                     KLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDGK
                     YVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRLY
                     DNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTLD
                     GAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQPL
                     HLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIIDG
                     VLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPNDS
                     SLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTLK
                     VEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYILL
                     AAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(77029..77487)
                     /locus_tag="PB779_000070"
     CDS             complement(77029..77487)
                     /locus_tag="PB779_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDE0737626.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(77785..78303)
                     /locus_tag="PB779_000071"
     CDS             complement(77785..78303)
                     /locus_tag="PB779_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDE0737627.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(78305..78922)
                     /locus_tag="PB779_000072"
     CDS             complement(78305..78922)
                     /locus_tag="PB779_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HDE0737628.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSLYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(78919..79773)
                     /locus_tag="PB779_000073"
     CDS             complement(78919..79773)
                     /locus_tag="PB779_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0737629.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(79770..80681)
                     /locus_tag="PB779_000074"
     CDS             complement(79770..80681)
                     /locus_tag="PB779_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0737630.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(80722..82056)
                     /locus_tag="PB779_000075"
     CDS             complement(80722..82056)
                     /locus_tag="PB779_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0737631.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            82264..83094
                     /locus_tag="PB779_000076"
     CDS             82264..83094
                     /locus_tag="PB779_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HDE0737632.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(83338..83656)
                     /locus_tag="PB779_000077"
                     /pseudo
     CDS             complement(83338..83656)
                     /locus_tag="PB779_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(83778..83972)
                     /locus_tag="PB779_000078"
     CDS             complement(83778..83972)
                     /locus_tag="PB779_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737633.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(84477..84662)
                     /locus_tag="PB779_000079"
     CDS             complement(84477..84662)
                     /locus_tag="PB779_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737634.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(85512..85853)
                     /locus_tag="PB779_000080"
     CDS             complement(85512..85853)
                     /locus_tag="PB779_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDE0737635.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(85853..86083)
                     /locus_tag="PB779_000081"
     CDS             complement(85853..86083)
                     /locus_tag="PB779_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDE0737636.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            86370..86708
                     /locus_tag="PB779_000082"
     CDS             86370..86708
                     /locus_tag="PB779_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737637.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(86913..87152)
                     /locus_tag="PB779_000083"
     CDS             complement(86913..87152)
                     /locus_tag="PB779_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDE0737638.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(87128..87475)
                     /locus_tag="PB779_000084"
     CDS             complement(87128..87475)
                     /locus_tag="PB779_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HDE0737639.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(88207..88788)
                     /locus_tag="PB779_000085"
     CDS             complement(88207..88788)
                     /locus_tag="PB779_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0737640.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLIKERLLTSQKVL"
     gene            complement(88971..89597)
                     /locus_tag="PB779_000086"
     CDS             complement(88971..89597)
                     /locus_tag="PB779_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDE0737641.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(89619..90950)
                     /locus_tag="PB779_000087"
     CDS             complement(89619..90950)
                     /locus_tag="PB779_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HDE0737642.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(91105..91506)
                     /locus_tag="PB779_000088"
     CDS             complement(91105..91506)
                     /locus_tag="PB779_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDE0737643.1"
                     /translation="MKKAYETAMINHGGRNGEVEAPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVLEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(91592..91798)
                     /locus_tag="PB779_000089"
     CDS             complement(91592..91798)
                     /locus_tag="PB779_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737644.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(91893..93395)
                     /locus_tag="PB779_000090"
     CDS             complement(91893..93395)
                     /locus_tag="PB779_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HDE0737645.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(93413..93868)
                     /gene="argR"
                     /locus_tag="PB779_000091"
     CDS             complement(93413..93868)
                     /gene="argR"
                     /locus_tag="PB779_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDE0737646.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(93966..94583)
                     /locus_tag="PB779_000092"
     CDS             complement(93966..94583)
                     /locus_tag="PB779_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HDE0737647.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            94804..96177
                     /locus_tag="PB779_000093"
     CDS             94804..96177
                     /locus_tag="PB779_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0737648.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLFLSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            96252..97364
                     /locus_tag="PB779_000094"
     CDS             96252..97364
                     /locus_tag="PB779_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HDE0737649.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(97436..99073)
                     /locus_tag="PB779_000095"
     CDS             complement(97436..99073)
                     /locus_tag="PB779_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HDE0737650.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAAVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(99241..99849)
                     /locus_tag="PB779_000096"
     CDS             complement(99241..99849)
                     /locus_tag="PB779_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDE0737651.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(100233..101384)
                     /gene="queG"
                     /locus_tag="PB779_000097"
     CDS             complement(100233..101384)
                     /gene="queG"
                     /locus_tag="PB779_000097"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HDE0737652.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(101403..102155)
                     /locus_tag="PB779_000098"
     CDS             complement(101403..102155)
                     /locus_tag="PB779_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737653.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKIADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(102296..103246)
                     /locus_tag="PB779_000099"
     CDS             complement(102296..103246)
                     /locus_tag="PB779_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDE0737654.1"
                     /translation="MKTKKSLFLILAVSFLVLAGCGKQASDQADEGSKEKLSVVATNS
                     ILADMAKEVGTDQIDIHSIVPVGTDPHEYEVLPEDIKKASDADVILYNGLNLETGNSW
                     FDNLMETAKKEEGKDYFAVSKNVEPLYLTSGEEHTKADPHAWLDLSNGIKYVEEIARI
                     FSEKDAENATLYKKNAEAYVEKLKELDTQAKESFASIEENKKLLVTSEGAFKYFSRAY
                     DLPAAYIWEINTESQGTPDQMKAIIDQIRAKEVPVLFVETSVDSRSMERVAKETGLKI
                     YDKLFTDSIAKEGEQGDSYYQMMKWNIETIHEGLSQTKES"
     gene            complement(103247..104086)
                     /locus_tag="PB779_000100"
     CDS             complement(103247..104086)
                     /locus_tag="PB779_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDE0737655.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(104083..104829)
                     /locus_tag="PB779_000101"
     CDS             complement(104083..104829)
                     /locus_tag="PB779_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDE0737656.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            105067..106437
                     /locus_tag="PB779_000102"
     CDS             105067..106437
                     /locus_tag="PB779_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0737657.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(106492..107388)
                     /locus_tag="PB779_000103"
     CDS             complement(106492..107388)
                     /locus_tag="PB779_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDE0737658.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(107502..107672)
                     /locus_tag="PB779_000104"
     CDS             complement(107502..107672)
                     /locus_tag="PB779_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737659.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(107669..108346)
                     /locus_tag="PB779_000105"
     CDS             complement(107669..108346)
                     /locus_tag="PB779_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDE0737660.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(108437..109342)
                     /locus_tag="PB779_000106"
     CDS             complement(108437..109342)
                     /locus_tag="PB779_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDE0737661.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     ENFKNIALDTLKKQLEKQTAVSWTT"
     gene            109517..110941
                     /locus_tag="PB779_000107"
     CDS             109517..110941
                     /locus_tag="PB779_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0737662.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMED"
     gene            110987..112018
                     /locus_tag="PB779_000108"
     CDS             110987..112018
                     /locus_tag="PB779_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDE0737663.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGRFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            112025..113212
                     /locus_tag="PB779_000109"
     CDS             112025..113212
                     /locus_tag="PB779_000109"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HDE0737664.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            113368..114750
                     /locus_tag="PB779_000110"
     CDS             113368..114750
                     /locus_tag="PB779_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HDE0737665.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGIDRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            114877..115107
                     /locus_tag="PB779_000111"
     CDS             114877..115107
                     /locus_tag="PB779_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737666.1"
                     /translation="MTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGE
                     AYEDYFMIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(115307..115975)
                     /locus_tag="PB779_000112"
     CDS             complement(115307..115975)
                     /locus_tag="PB779_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HDE0737667.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        33441 a        24195 c        20805 g        37759 t
ORIGIN      
        1 actgtagaca tcatccataa aatggacttt gtctacagtc tgaaatcacc actgatgatt
       61 ttctcttttg cgtctgaaac tgcctgatag gcttcctctg ataattgtcc ttttgtcaga
      121 tctacccctt cttctttcaa accaaaggtc aaatgcttgc cgccaggaaa tttatcgtta
      181 tgagaagttt ctgcaaattc tttgacttct gcaccgacat ttttctttgt agaagtcaac
      241 gtgaaattcc ctgtctcgcc gttctccatt ttataatccc cttcatccgc ttgatcgcga
      301 tctacaccaa tcacccatac ttttctgcta tagtcgtttt cattgcgggc ttttgcttct
      361 tggaacaccc cagctccagt acttcctgcc gcctgataaa gaatatcgac tccctctttg
      421 tacatagaag cagcaatagc ttttccttta tctagcgaat cataggatgc agcatattgt
      481 acgttaacag taatttcctt gttcagtgct gtggcccctg ccttaacgcc agcttcaaat
      541 ccgctttgga aacgttggat cacgggccct tccattccac caataaagcc tacttgatca
      601 ctttttgtcg tatatgcggc agctagtcct gctaaatacg cactttcttg atctttaaag
      661 gttgctgatg agatattctt tttcccagta atctcaccat ctaccaaggc aaatttcaac
      721 tttggattat ctttagcagc attttccagt tcctctgctt gcaagtagct caagctaata
      781 atggtggtaa agccgtttct gattgcctga tcgatattgg tactgttatc ctctggattg
      841 ttcgtttcta tatacgtaaa atcttttttt gctgtcagct ttttctcttt tccccaagcc
      901 tctaatcctt cccagccagc ttgattgaag gagcggtcat caaccccgcc aaatccaaga
      961 accaaagcga ttttactttt ctctttttca ctttgcttct ccccctgaga ctgactacag
     1021 ccgactaacg ttactaatga caccaaaaac aacaatgaaa caagtatttt cttcaaaatt
     1081 tttctcccct ttttatgtgt cttgacacat tgaactttta aaagtatagc ataccaatat
     1141 atagaacact actcttcaac gaagattttc cgtttcccaa tttctccact atcaaaaaac
     1201 cagcaatcac ttctgactgc tgttttttta tagctgttat tctgctttta ctggactact
     1261 tatattctca gctaagtcct ctaaagcttc gatatcatga atcaagtaat aattcttttt
     1321 cttttcgata atattctcct cacgaaaatt cgtgattgtt cgtaaaagat gtcgataact
     1381 gacatttaag attgaggcgc aggtggttaa ccgaaatgag aaacgttcgt tttcgtgatg
     1441 ggtcaaaata aactttgcta aacgagtttc aacaggttct gtcagtgagt tcgccaaatt
     1501 tatcccggaa tttaaacgat aacttagtaa ctggcaaata ttctgcaaaa agcgaacatc
     1561 tttttgaagc tgtgttcgat attgatttag cggaatgctg atacagatgc acttagtcac
     1621 tgctttaacg ctgcttttcg gcgataattc ccacaatgaa gaggcttcgc cgagtggtgt
     1681 agcgggcttt gcgtaatcga tgcaaatatt ttgtgtatca gaagaatacg agtacaccat
     1741 taccgtccca tccactaaaa aatacaaata atctgaggtt tttcccgttt gaatgaggtg
     1801 ctcttccttt tcaaaaaaaa gtaaagaagc cattgccaat atatctgaat ccatataatc
     1861 ctgcaggttg tgcttctcaa cgtaagcagt taattgcttc gtatcatgga tttttttcat
     1921 gaaatcgtca cctctaagaa gtttttcttt attatagctt agattgtttt tcggctcaat
     1981 acgaataatt atttataatt gtttgtaaat tgtatgtaaa agttgtgtaa aataggacgt
     2041 gcgtcacttc attgattttg attccctgct atgatttaga cgtattagaa attatatcca
     2101 acaggaggag aaaaatgcag ttcaaacagt tagcaaaagg gttcatcgga gtcatgttat
     2161 tgaccacttt ggcggcctgc ggttctggga atacaagtag cagctcagaa aaagagagca
     2221 aagaaaaatt agttgttcaa ttcgttccaa caaacaatga tggtagtatg gaggcaaaag
     2281 caaaaccatt tgctaagtat ttatcgaaaa agttagatcg tgaggtagaa gtgacgttag
     2341 ctactgatta ttcaacgatc gtcgaagcga tgtcttctgg tcaagtcgat gtcggaatta
     2401 tgccgcctgc agcctatgtt caagcaaagg atgctggagc tgcagatgca atcctgactt
     2461 ctcagctcgg cgattatgat caagaaactg gcttgccatt aaaggacaaa cttacgaaca
     2521 cctttaaagg agaagtattg gttcgtgccg atagcggatt gaataagtta actgatttaa
     2581 aaggaaaaaa tatcgcaacc ttaagtccta actctgctag cggctacatc tatcctgtcg
     2641 ctgaattgaa agatgctggg attgatccta ctgcagatac aaagatgacc actgtgaatg
     2701 atattccgag tgagattacc gcagtgttga acaagcaaat ggatgcggcg tttgtttttg
     2761 aaggcgcgcg aaatgttttt gcttcgaatt tcccagataa tgatttattt aaggatttaa
     2821 aagtcctgta cctgacaaaa ggcgatattc cgaatgacgc aatcgctgta cagcctgaca
     2881 tgtcaaaaga tttaaaagcg aaaattaaag agaccttctt aaatatgaag gatgataaag
     2941 atggcaaaga agcaatggct ttgtgggggc atcagggcta tgaagaagct gctgattctg
     3001 cctatgacac gatcagagac tacacgaaaa aagcagcaga ataaaacatc agtaagtgtc
     3061 agcaagcttt tttttgctta cacttaaaaa aatggagaag gataatgatt atttttgaca
     3121 atgtttcgaa ggtctatccc aatggcgttg ttggcttgaa ggatattgac ttaacaattg
     3181 aagatggaga atttgtttcc atcatagggt tgagtggtgc tggaaagagc actctgctgc
     3241 gcagtatcaa tcgcttggca gaaaccacca aaggagatat tcgcattaat ggaacctcta
     3301 ttacaaaagc gaataaaaaa gagctgcgac agattcgccg ccagattggt ctaatctcgc
     3361 aaagcttcaa tctggtaaag cgtagtacgg ttcagaaaaa tgtgctatct ggacgtttgg
     3421 gctattactc cacttggaaa agtattttag gtctttttac gaaggaagac taccagcaga
     3481 caaaggaagc actggaaaaa gttggtttgt ctgataaatt gcagacacgc agtgatgagc
     3541 tcagtggtgg gcaacaacag cgagtatcca ttgcgcgagc actcgtgcag caagccccca
     3601 ttattttagc ggatgaaccc gttgcatcat tagatccaat cacgactcaa aaggttatga
     3661 tggacctaaa aaatatcaat caaacgatgg ataaaacagt cattgtcaat ctgcattcag
     3721 tccctctggc tcgtgagttt tctacgcgtg tgctcgcgtt aaaagctgct caggttgtct
     3781 ttgatggtcg tccagacgac ttaaccgatg aacgcttaga gcaaatttat ggcaatgcaa
     3841 tctttgaaga aaaggcaggc gaaatcgatg agcttgaaag aaaccgttca ctttaaatgg
     3901 tataaacacc tgcttattct tctgttctta attgtttgtt ttcaaggaag tgcctggatc
     3961 acgtcagctg atttttctca ggtttttcaa aactccaatc aaatgactgt ctttttatca
     4021 cgcttcattc atccagactt tagctattta cctaaattag tcgagcctat ggtgaaaaca
     4081 cttcaaatgt ctttgcttgg aacggtcatt ggcttaattt tagcgatccc tgttagtttt
     4141 ttagcgacca ctgtagtgac agaaaaccgt cttctttcta ccatctttcg ttttctttta
     4201 ggtttagtac ggaccatccc taccctgctt ttagccgcgc tttttgttgc tgtgtttgga
     4261 attggtgaag cgactggcgt gttgactatc gctgtcttta cttttggtat ggtgtcacaa
     4321 ttaatgtttc aagcaattga aaccattgac tttggcccga ttgaagccgc tgcggctgtt
     4381 ggagcaaata aaatgcaaat cgctatttgg tcgatcgctc cacaagtttt gagtcagttt
     4441 gcgagctatg ctttttacgc gtttgaggtg aatgttcgtg cttctactgt ccttggatat
     4501 gtcggagctg gtggtattgg cgttattcta aattcctcac ttgcgctttt gaattatgaa
     4561 cgagtttcaa tcattattct aacgatccta gtaactgtcg cgatcgttga taaattaagt
     4621 gaacgtgtca ggaggtccct gttatgatgc ttcgtgaaat gaacagaaga acccttttat
     4681 cattagttgc tttagtgatt ctcgttattt tgtcggccgc tactctggat tactctggat
     4741 taagcacctt ctctccttcc atgggaatgg acgttttgag agggttaggt cagcctgatt
     4801 ggcagtttct atatgatggc agcggcgagg atttgattag tttgctatta ttaaccattg
     4861 gaatcgcctg tttagggaca atgatcgcta cggtattagc gattcccatt accttgatca
     4921 gtgcggttaa cctctggcaa gcacatccat gggtaacaaa aattggcaag cttatctgta
     4981 atgttttacg agcttttcct gaactagttt ttgcaattat ttttgtgaaa gtcgtcggac
     5041 ctggcccctt tgctggtgtt atggcgattg gcgtccatca gatcggaatg cttggcaaac
     5101 tttttacaga agaaatggaa gcgatggatg agcgacttgt tgaagaaatg catgcggtag
     5161 gagcaaattt ttggcaaacg attttctttg ttcgcatccc ctatttgatg ccgatttatt
     5221 gttctttagc attaaatcat tttgaaatag cggttcgtag tgcggctacc ttaggcttag
     5281 ttggcgctgg cggaatcggt gctccattga tattcgcgat tcaaactcgg tcttggagca
     5341 aagtgagtat tattttgatt ggcgtagtcg taaccgtgtt tattttagat caaataaccg
     5401 gaattataag aaagagattg agataagaat gaatatattg catatatcag atatacactt
     5461 tcgcagagag tatgaggctt gtgaagaagg ctataaggga atgctggcta cgatgcagaa
     5521 tccccttatc cctctggagc aatgcattca tcatctcctg cagcaaacac ccttggacct
     5581 tgtgattatc agcggagatt taaccgaaga tggcgaaata gacgattatc gatacttgaa
     5641 gacttggctg gaaaatgcgc taggagaaac gacgattctt gttactctag gcaatcacga
     5701 tatcaaagaa catttttggg taggctggtg cgatgaagcc gcctcttctg ccccgtacaa
     5761 ccagatagtc aaatatcctg agtttacagt gatttccttt gataattcaa gctatggata
     5821 cgcagatggt atagtggacg atcagcaatt tcaatggctg aaaaaagcct tagagcaaga
     5881 aaaagaccaa ccgattttct tggtcaccca tcatcatcta ctgtctcacc aaagcagtat
     5941 accaaaatgg cctggtaccg aacgtttctt gaagctaatc gcaccttacg atattcgctg
     6001 tatcctaaac ggtcataccc atcacacatt tactgatgaa attaatggga tcccctattt
     6061 tactgtatcg agtatgtcct ttgttggtga agatgaaggc gatggcttcg tacgctttga
     6121 agaacgtcat gggtataacc tttatcatct cgatcaagga aggattgttc gccagacaac
     6181 agaaaacttt attccaggca acattttaaa aacacttcaa atgaaggatt aaggcattat
     6241 aaatcaaaaa aagagaccga acagctgaat acgcttcggt ttttctattt tgagtcagct
     6301 aaaggagcac gcagaatgaa cattacgttt ttagagacaa gtgatatgca tggctatgtt
     6361 tcaccaacag actattccgg cagaaccgat ctggccttag gaacggctaa agtatcgtcg
     6421 aaactgaagg aattacgggc aaaagcagat ggaccggtaa ttacgatcga aaatggtgat
     6481 ttcatccaag ggtctccttt gagttattat cttgctaaag aatatggttc agccaaagag
     6541 cttacagact tgattaacca aatgagctat gatgttcaag tgttgggaaa tcatgagttt
     6601 aactatggtg tggattatct cgaggaagcg attaagaatt atcaagcgcc tatattagga
     6661 gccaatatgg tgaacaaaaa tgaccaacca tactttggaa acgcctataa gattatcgaa
     6721 aaggtgggtg taaaaattgc tatcttggga ttaacgacac aatacattcc tcactgggaa
     6781 aagccagaaa ccttagcagg aattacgttt aagagtatcg tcgaaacagc aaaagaatat
     6841 gttcctctat taaggaaaca agcagacttg gtaatcgtta gttaccacgg cggatttgaa
     6901 aaagacttgt taaccggtga ggacacagaa gcgctaactg gagagaatga aggctacgag
     6961 ctattgcagc aggttgaagg cattgacgcc cttttcaccg gtcatcagca ccggaaaatt
     7021 gctgaaacgg ttcatggagt tcccgttgtt caaccaggct atcgtggcga gttcatcggt
     7081 gaaattcgtc ttaccgtcga gaaaaaagag gggcaagtgg ttgttacaga tcaccaggtt
     7141 gctttacact cagttgaaaa atcagagcct gatccagaaa ttcttgcagc gatcgtaccg
     7201 gtagaagaaa aactagagaa atggttggat caacccttag gtaaagtgaa cggaaatatg
     7261 cgtattaatg atccgatgca ggctcgtctt gaggaacatc cctatgtaga gtttattaat
     7321 cgtgtacaat tatttgccag cggctcagag atttctggaa ctgcgttatt caataatgaa
     7381 ggaaaaggct ttggtgagac gatcacgatg cgggacgtca tcaccaacta tatttatccg
     7441 aatactctgg cagtgattca aataaatggt gcagatttga gagcggcgtt ggagcagacc
     7501 gcaaattatt tagctgtaga aaataaccaa atcgtattca atccagcctt tattcagcct
     7561 aagccccagt actacaatta tgacatgtat gaagggattc agtacactat tgatatgaaa
     7621 cagcctgttg gacaacggat taccgaactt cgttttaaag gtcaccccgt tcttccgcaa
     7681 caaatgctgg aagtggtgac aaatcaatat cgggcaatcg gcggaggaaa ttatgcgatg
     7741 tttggtgcgg agaaaattgt ccgagaaatc caaatcgaca tgaccgaatt aattgccgac
     7801 tatttgaata ttcacccacg catcgaagca aaagtgaatc ataattttca agtgattttg
     7861 tagtatataa ataaaaaatt caaaaaggtg tgagcagttt tttgcccaca cctttgttat
     7921 gccaaattgt taggctgtct gatttccatc cagccattct ttagccagcg atctacctca
     7981 tcaaaacaaa aaattttcct ctgatggttc cttaaataag actattttga tcctttttcc
     8041 atgaataaga ttttgcatca gacaatactt catttctgaa aaagttgcgg caccaatata
     8101 gcctaatacc cctttccgat cttgattaaa tacaaaaaat aaatccgctg ctgcgatatt
     8161 taaaaaaaag tcgtcaagat ttctggatac tctttgtcta ggatcggaca tgagcgagga
     8221 taatcaatta attcaatgcc ttttttactg aaatcttttt ccatatctcg atattcttct
     8281 tggaaaacaa tacttccaga aataacagct ttcacaaaat tggcctccat ttttttattt
     8341 ttcagacact ccaccatacc ggatacctct caaagaaaag acatagcaaa aatcaatagc
     8401 agctatctct ccacggtttt ttactggtaa ttttattttt cttttggaaa ttgtatcagg
     8461 aaggtcgttc cttcattttt tcggctggtc acttcaattg aaccgtggtg caggcgcact
     8521 agttccttca cgattgataa tccaagacct gactcgccta tctttgtatt tttacttgac
     8581 ggatcggctt tataatagcg atcccaaatg tttttttgtt cctcttcaat catgccgatg
     8641 ccattgtcct cgacagtaat aaatacaggc tctttgtcaa atgatgttgg taaagagaaa
     8701 tcttagaata atttggacag aacagaaaga agaaactctc tttctgttct gtttatttgg
     8761 ttaaaaatgt tttgccatga cgaatcatga tccgtagttt gaaattgtaa aagctgcgaa
     8821 agccgtacgc attgcgtttt aatactttga tgtggttgtt taaacattcc aatggtccat
     8881 ttgaatagct gtagtgaagc gcattttgga tctgtggcag aaacttttta aacgttcgta
     8941 aagtggttgt ataggtttca ggaagaccgc tgacttctct gtttaaacag tcctcaaata
     9001 atgactgatc tcttttcttt accgcataaa gaatgtcttg gtataactga tagccttggc
     9061 gcaggttggg acaagcagat aacagtcgat cgacaatctc actttcagtc aaataatctt
     9121 taaaactggc acgccaaacc cttttttcgt agtttaactt tgcttcttct ttttgtagga
     9181 gtttccaata gcgtttcaat tttttcccta accctcgttg agagtgggaa gttcctttaa
     9241 gccgtgccgt ggtttctttc actcgatgat tcaagaaggt tctgccaata tgttggacga
     9301 tgtggaaacg gtcgatgatc aactgagcat tcgggaaaag ctttttcacc aatgaaacat
     9361 aaggcgcata catatcaata acaatccatt gaacggcttc acgagtcgct aatgaaaacc
     9421 gagaaaaata gcattctaaa taaggcaagc gtcgattttc gacaatatcc aataatgcat
     9481 ggctttgtcc gtccatcatg ataaaactca ttgcactggc aacacttcga accgatttga
     9541 attcatcaaa gcataagacc tttggcaaag cctgtttgaa aggattcaat gggcggtaga
     9601 atcgcttcat gacacgatag accgaagaag tggaaatatt tttctgacga gcgatttccg
     9661 tcatggaagt attctctttt aagcgagcaa tgacagacca acgaactttt tgactaatga
     9721 aacagtgttt ttcagcaaca gaggtatccg ctacgaatgt tctttggcaa gacttacatt
     9781 taaatcgttg tttcttcaac tccagataag tgcgatactc agacgcatca ttcagtaaca
     9841 accgaacggt tgtcgtcccc caacgaatga tcctagaggg gacgacacaa agacaatggg
     9901 aacactcttc tggcttgtac agaagagttc ctttgtaaat catggatttg agtcaatatc
     9961 ttggacacat tttagtagag acggttaagc cattttttct tttgctaatt cttcaaattc
    10021 ctgtggggtt agatagtgaa tcgagctatg gattcgattt cggttataaa atccttcaat
    10081 gtagctaaat agcgctcgat ttgcttcttc aaaatctgag tagctagtcg tgtagacttc
    10141 ttcttttttc aatgaggcat ggaaagattc gattccagca ttatcataag gtgttccttt
    10201 tctactataa gaatgcctta ttttgttggt tttaagccat tgttccactt ctcttgctgt
    10261 gtattggctg cccaagtcag tgtgtagaat cattccttct ggaatgtgat aatgtatttt
    10321 tgctttattc aatgtttgaa tgacacaatc cacagtcatt cgttttgaaa atgtataact
    10381 aataattttt ttcgtgtgta aatccatgat tgaagataag taacaccaac catttttctt
    10441 agtaggaatg tacgtaatgt cagctgccca tttctcacag atcgtttcag tagaaaagtc
    10501 ctgatttaag agattctctt ttgaaatgat cggtttatta gacctttgag gtctatattt
    10561 tttaactaca atcgacctta aatttaattg tttcattagc ttttggacat gtttaagaga
    10621 tactgaaatc ccttctttta ataaaacttg atggatcttt gtggcaccat agcgttgttt
    10681 attcgtaaaa aaaattgttg aaatcttctt tttcaactta ttatttctga tttctgtagc
    10741 tgtcaacggt ttattcttat aaaaataata gacacttcta gggatttcta ataaccgaca
    10801 taacaaagaa acagtgtaat ccttacacca tttttcaata aattgaacaa gcgaatttag
    10861 gttttccgag agaatatggc tgcggctttt tttaagattt caagttcctc atttaaacga
    10921 gcattttctt ttctcagttc agctacttct tttccagtca gtcctgtgga ctgatcaggt
    10981 aaatataaat tcttccattt gtaaatcgtt gcttcagata agccatattc tttcgctaac
    11041 cctcgaacag aacgtccagt ttgattcagt tcaacaatca tttgtttaaa attttcttca
    11101 tatcgggtca taaaaattca tcctctcgta gataagttta atttattctt gtctctacga
    11161 aaagctgtct aagatttgat actaacacca agttatcttt agaaccattt cagatacata
    11221 tgaaacaatt acatatgatt ttttcataaa aaaacagtac tgtctagtag tataaaatat
    11281 acaaatttct taaaaatttt ttcactaaaa tcactacctg aaacagtcta aaacacttat
    11341 atatcaacgt ttaatgaaac tatctccgtt tcatttcaga tacaaataaa tatagtcggg
    11401 ctccaaatcc gaaaaaaaat acccccagta gcttatccta agctactgga gatgtataag
    11461 tacggtcata taacaacggg gtagggtaaa taaatgaaaa agatggaaga atcattattc
    11521 aataactttt ttaaatactt cgttgtaatc agttacctgt ccgttcttaa ataccacaga
    11581 ataatctttt ttcccatttt caagtaaccg aagtggaatg tctttaccaa cttgctctgt
    11641 cactgcatta ctgatacctg ttagattagc taataaatct gataaagatt gagcatctgt
    11701 agaaatctct gtatcagtat ttatcgtgat tcctttatct tcatttacaa gcttccaagt
    11761 aggtggtata gctgtgtatg tttcgatgaa tgaatcaatt ctttcatcta tcgtcttccc
    11821 agtatctact tctgtctcat tactcttaga tgaatcgatt ctttcatcca tcgtctgctc
    11881 cgtaactgct tctgtctcat tattctcacc ggaaactctc ttcacaccca aacttatata
    11941 ttgtccatct ttagtgtgca tagttaaaat tcccacgctt ttactaataa attcactata
    12001 accagttctt tcaatagaga cttcaatgta tttcacacta tcatactcaa aagaaaaata
    12061 gacatgtaaa agcattttgt tgtttacatc tacataataa tcctttgact ctacttgaga
    12121 ccttcctata cggaatacag ctttactgtc tgatatctct ataccagcat ccttattatt
    12181 aatctgccaa tctccaagta gctcttctgg caagctagta gtttcttgtg aacactttac
    12241 cacttcactg gtagaggtcg aaacattcac ctccgcactg ttagaagaat tttccaagga
    12301 atcaggagcc ttagcacaac caacaagtct ttatatattg tgcagccgat attttcttca
    12361 ttcagtacac ccttgaaata tgcagtgtta gataaagcag ttcgtcctga tttgctgagg
    12421 cacccatctc ttcttgaacg tactccttga ttttcaaggc cgcccgatac tctttcggaa
    12481 aacgctgctt cactgaagcc agcaaaaaat catccttctc cggcaactct tccttcttaa
    12541 tcattcgggc aataaaaaac tgtaaatgcg tcacaaatct taagtaaagc atcgaatctt
    12601 tatcaacctt tttttcggga aacagatatc ctagcatagc caagatatcc tttagtgctc
    12661 ttaccgagag catggtttct tccatatttg cttgttcact ttgggcattt acaatgtgaa
    12721 acgcaatgtt tccagcctcc tcttctggca actgaacatt catttttttg ttgatcaatt
    12781 ggatagcata gcagccgatc tcaaattctt ttgggtaata cttttgaatt tcaatcagca
    12841 ggcgattttg aaaaacaatg cctttttgac tgcgttcaat ggcatgcttc aagtgatcaa
    12901 ccaaggtaaa aaatagactt ttattcagct taaagtcaaa cttggcgttg gcataatcga
    12961 taattcgctt gacgcaaata attagatcat ccggagcagc ctcaaacagt ttaatgtaat
    13021 ccttttttag agcatcagaa agtgaatcta atttaaatac tttttggatt ttgtcagccg
    13081 gaaccaaatc gcctttcttt agttgaaatc caatcccttt ccccatcaaa attacttctt
    13141 tgccttgctt atctaagcaa agaattaaac tgttgtttaa cgttttaatt actctcatta
    13201 gattcaccgt tctctctaag ctaagccatt tcttgcgatt actttttgat accaaaagaa
    13261 gctttctttt tttattcgtt ttaattcttt aagattctca tcggttcggt caacatatat
    13321 aaaaccataa cgcttattga agccttgatg ggtactaaca acatcaatcg ctgaccaagg
    13381 taaataacca aaaacatcta caccatctgt taaagctgct tgaatagcca gaatatgttt
    13441 ggctagataa tcaattcgat cctggtcatt aattcgtcta tcttcctcaa ctatgtcggg
    13501 tgccccatag ccattttcag taattaaaat aggtaaatca tagcgatcgt acaatttcct
    13561 caatgttaat cgtagtccag tagggtcaac tacccagcca tatggcgttt tatctacata
    13621 aggattttca gctgcccggt agacaccttc ttctcccaac atgatctgtt gatcccccgc
    13681 tctagcggaa acatctgatc cgtcattttt gctggcagcg atggtggcag ttgaataata
    13741 attaatcgca ataaaatcgg gtttaccgga ggataaaatt gcctgatcct ctgcctcaat
    13801 tttaggatat aatccacgat cattcaaata gttttcaaac aaataattgt attttccccg
    13861 aactgctaca tctaagaaag accagcctct caatgtttcc caattatggg ctgcaattgc
    13921 atcttctgga ctggaggtag cttgatacat agccgttaaa ttgattgctg gaccgatttt
    13981 tcctttaaga ttcaactgat gatacaagtg aattactcta gcttgagcta ataaaacatg
    14041 gtgattaatt tgaaagagtt ctttttttga aggcagctct ccacttggtg gcaaaccaat
    14101 cgctccagga tgaaggatca tcgtgttttg ctcattaatt gtcagccaat agttcacctt
    14161 gtcaccatac tcagtaagca atacctgtac atagtccaca aaataatcga tagttgctcg
    14221 atttaaccaa ccgccctgct cctctagaaa ataaggtaaa tcgaaatggt acatggtgac
    14281 aatcggttcg attccctgat tcaggcattc atcaattact tgatgataaa aagaaattcc
    14341 cttttgattg gttttattat tttcaatatc cataattcgc gtccaagcga tggaaaagcg
    14401 aaaagctttt aagcctaatt ctttaaacag ctgtatatct tctttatagt gatggtaaaa
    14461 atccgaggca acttcaaaat tagctacccc ttctgtatgc tgatacttgt caataataga
    14521 cggttgtttc ccatcctcct gataggcacc ctctgcctgg taggcactaa tggaggcacc
    14581 ccataaaaac ttctctggaa atgctgaaag ctgtttgtat tgcacaaaaa tcctctcctt
    14641 aactaatttg catcaatggt tcgtgttcct ttaagcttcc gcttgcttca ctaattcctg
    14701 cgtaattttc actgttggtc actaccacaa tcactgtatc atcgtagcca gcgtttctaa
    14761 tggcagcgaa atcggcgttg attaataatt gtcctgctga cacctgatct cctgctttta
    14821 caaatacttc aaagggttcc ccttttaaat tcacggtgtc gatccccaca tggatcaata
    14881 attcaatacc ttctttagaa cgtagaccaa tcgcatgttt agattctaaa atagtaatga
    14941 cttctccctc aacaggtgaa taaatgctgt tttcttctgg atgaatggct acgccctttc
    15001 ccaatagtcc cttagaaaag acagcatcgt tcacttcaga aataggacac acggttcctt
    15061 ttaccggatt ttcaacaatg actgcttcgg ctattgccgt ttgctctgat tcatcagaag
    15121 tatcgtcaaa tccaattaga taagcaatga taaaggttgc aacaaaggcg attacacacg
    15181 taataattgc gtgaacaata ttcattggat tttctccaat aaaggctggt aaggctgcta
    15241 agccagggga aacaaaggca tatctgacta aaccgctcaa gccagcatac aaaccagcaa
    15301 ttgcaccacc aatcatggaa gcaactaatg gttttttcag cttcaaggtt actccataga
    15361 gtgaaggctc agtaattccc attaaagcag tgatcccagt ggacacagct agctgcttca
    15421 actctttgtt tttagttttc gcggctacag caaaggtagc acctgattga gcaatattag
    15481 aagccagcat tcctggccca ttgatcattt cagaacccgt actgctcaat tgcatagtag
    15541 cgattggcgt cattgcccaa gctgtacccg taaccaccaa aaatggctgc aaaccaccca
    15601 tcaaaaatgg aattaaccaa gctgctttgc cgttaatcca ttcagccccc attgctataa
    15661 gatcgttcag caacgttcca aacggtccaa tgacaaccaa cgctaaaggc cccataatta
    15721 aaaataccag catcggctta gtaaagaatt taataaacga aggcgaaatt cgatccgcaa
    15781 agggctctac ataggacatg atccaaacag taaagataat cggtaaaact gatcccgcat
    15841 aatctgcagc taataccgga attcctagaa aagaaacggc atcgccagta gaaaaaagct
    15901 gtgaaatatt tggatgaagc aaaatgccag caacagtaat cgccaaaatt gggttgacat
    15961 caaactttat ggctgcccca taggctaata gtactggcat aaaataaaag gctgcatcag
    16021 caatagtatt caaaatgatg taagtttgac tactgtctga tagtacacca gtcaaagtca
    16081 agacggccaa aatggctttt accatcccgg cacctgttat agctggaatc atcggtgtaa
    16141 aggtggtaga aatgacacta atcaatcttg aaataatact ttcttgattg tctgaagagg
    16201 ggcccttttt aattgaagtt cccacttcct tttgaatttc cttgaaggct gtttggactt
    16261 cattgccaat caccacttgg tattgtccac cgctatccac cacactaatt acaccaagtg
    16321 ttttttctaa ggctttcgta tcggctttcc ttttatcttt gagttcaaaa cgcagtctgg
    16381 tggcacaatg ggttaagctg accacatttt cttttccccc aacctgttgc aatacatttc
    16441 ttcctacttc tctgtaatcc attattctct ctccttaaag cagtaaaaaa gaccaagtca
    16501 aaccacgccc caatcaacat tgaagtgtta gtttgtcttg gtcttgcctg cataatcagt
    16561 aacatgccaa taacgttatt ttgctgtaat ccaataatag cacattatga tagcgcaatc
    16621 aacagggaat ttaatttttt atcttttcgt ttgaccgtat agggtaatat aacagttaga
    16681 tcacatcaac tagggtatat ctgcgtatac ttactgctaa aataagtata tctaatatta
    16741 actataccag taaaaccatt cctacataac cagcgggaaa ttcccaaaat cgtgaaagca
    16801 tcaaaaatgc atataacgga tcacacaact tcaacaattc tgctcttggg aaaaattgat
    16861 gaatttggtg agtaaaggat ggaataaaca gcattccaac aatataggca acaatagtga
    16921 tacttgtttt tttggtaaaa atcagtaagc aatagccaat ttcaatcatt ccgagatata
    16981 aaggtatcga tagaatgatt tgggctagta ttcttaaaaa ttaactagca aatgtttaaa
    17041 ctgatttatt tctaatctac atgtagtaag tatttcaatt ccaccaatta tcaataaaaa
    17101 taccaaacat atccataata attttttctt tttcatttct tttatattgt tataacagtg
    17161 aataacataa aaattcccga caatcattgt aatatttttt tgtcacctgt attagtattt
    17221 aatttatagg aaactataaa aactccctag tgaatttaca cctttgggag ttcctgtttg
    17281 gacggtatgc ataatacatt taaatcaatt taacattaac acctcagcat atggtatctc
    17341 cacatatata cggtctttct ttggatagta ctcaatattt atgttgatag cacttccatt
    17401 gtctaatata gctttagccc ggtatgtgtt atctccattt tcatgagtaa tcgtcacatc
    17461 atcacatgat cgatttaagt tgtactgttc ttgtaaaatc tgtgttacca atggtttcga
    17521 tgacttctct aatccagatg tacctgtcat ttttgaaaaa atgataccta taatagccaa
    17581 gacaacgata actataatga taaacttctt gttcatattt actttattca actttttatc
    17641 tcctatctcc aaaataattt gctcttatcc ctcttatcag tacattgaca tccctaaaag
    17701 tacaccaaag attgctccag ctacccctgc tatcatcaaa atcgtaccca tttgttcatc
    17761 tttatctcga tataagtagc ccataataac agcaacagca ccaaatacaa caggaataaa
    17821 tgctaacgct actaccatag aaatccaacc aataatcaaa tacagcttcc ctgtctcttg
    17881 tccatgtacg atttgttcct tcatttcatt aattgtctgc tcagtacttt tctttactgc
    17941 gtctgctcca gttgtctcat ctgtttcttg tagtgctccg caaaactggc aatacttact
    18001 ttcatctgtt atttctttgc cacattttct acaatacatg tcttctcctc ctaaaaacat
    18061 tcaattgttt attagttaac tgtttacttt attaaataca tcagaaaaca gctcattcat
    18121 tggtacactt aatatctcag aaagcatctt catttgatag ggtttaggaa tcgttctccc
    18181 tgtttgccac gaacttacac attgctgtgt aacattcatt tttttgctaa ctccgtttga
    18241 gaaagtcctt tttcttttct gtatcggctg agattactta cttttttcat gattctcccc
    18301 tcctgtttta ttatatacaa caatatgatg tatttcaact cataaaatat aaaaaaactt
    18361 caaataccat tacaaataca acaacttgtt gtactatact gagatggggg tgtattaatg
    18421 aaacagaaac aatatgcaaa ggtcattaga gaaaagcgaa aagctctcgg gtggacacaa
    18481 aaagaattag ctgaaaaaat cttctctaca caacaggcag tagcaagatg ggaaaattct
    18541 gtaacagagc ctaacctcga tagcttaacc gctctttcta gagccctagg aacccctgta
    18601 agccattttc tagacaatgt tgtcgtagat tatgaggaag agtttttggc tctctatcgt
    18661 tctcttagca ctgaagatgc agttcgaaca attgactata tgaagctatt aaaaaggcaa
    18721 gaaaatgaac gcaatcagct attgaaagat tgaaaaataa ataacccacc gaactttaac
    18781 ggtgggtgta ttgagatgaa ataagattaa gagctatgga taacctgtct agtttaatac
    18841 aattgggtct tttctcttcc ttactctccg tccatcatct cttgttacac ttgtaaattg
    18901 ataaagagga actaattcaa ctcctgataa tatcaattct tttattactt catctatccc
    18961 tgctcctttt gctaggtaga ctaaaaaact actacttgct ttcacattgt atagtctctt
    19021 aatatcctta gaagctcgtt caagagtgaa tccttgttta acaaagtagc ctctgttttc
    19081 ttttaaagca ttttccacgc tgttattccc aacattacgt agacgttcac aaacagtgtt
    19141 agtaagttct ttctctgtca ttagatatgt tccttgccac gataagccct gtaaaacttc
    19201 atgtgcttca tctaaaatca attgtttttc cttgctaagt tctgatcggg aattttgagg
    19261 aaatactctt ttagcctctt tttcgttaaa acatatctta acccattcat aagaaaaata
    19321 ttgatatgta aaatgaaatt tttccagaag tggaaggata tcttcattca atttttgaat
    19381 cacagaagtt gcattaaaaa cgtctaatcg atagacattg cttctcttat gattaaagtt
    19441 tcctaacgct ttctcttcct ttaacctatt taggtattcg agcatcttca aaggaacatc
    19501 ttcatcatct aattttttta tcaatcctat aaaagtcata agtgatagta acttattaca
    19561 tttatctatg tcataagttt taccatagta aaaactcatt tttttagcta attgttcccc
    19621 cgacaaaata caagtcacac tttccttact atcatcaaaa aaattaacat cagaaagcaa
    19681 gacatcatag acacgtcgca tttcctctag ataattcctt attgtcctga aaagtttgtc
    19741 tttcattgat tcaagagtgt caaaaagtac ttttgattcc tctttcaatt ttcgaaaatg
    19801 tgtaggatac aagtctaggt tctctaatag ccaattaaat gtttctaccc gactgtcttt
    19861 ctttaaaatt agcatcacaa ctccaataaa attttcactg atatcacaat tactggaatg
    19921 acaataaaaa atggaatgcc cagttttact ggtaaaaata ctagcagagg gattatgatc
    19981 gttgtgaaac agacatctta agtttttact tgacttaagt aatttattca tatcaatggt
    20041 taacaatctt tcataaatct cattaaaaga catgtcggag gaatcaaaca ggcagtcttt
    20101 aaaccactgt ttcatttctt ctttgtcgtc attttttatc aacttaacaa aatcggtttc
    20161 attgactagt tcatactctc tccctgaatc actttgacaa tttttagaac atgtcatggt
    20221 aaaatcaatc ggaagctcag taatatctaa catgttgtct tcattaatta ttatcactgc
    20281 atctgactta tatcctccaa aaaacattct attcgaagca tttacattgt catcacaccc
    20341 ggggatgttc tttttcaagt attcgtaaac agcaaccatt ttaccatagt cagtaattgc
    20401 ttcttttaat agaaagacaa tcttgtattt ttctagattt tcagagtacc gaatactttt
    20461 ttgtatcgca aacgcagaat tatgaactaa attgatagat aaaacctttt ctatgcttaa
    20521 gtatctacta tcatctttac tcaaatctac taccttcccc ttctcatctt taacagtgtt
    20581 atcgacatcc agaataatta ctctggtttc cacaaaactc tccttgtcat tgcctttatt
    20641 ctttgtcttg cttggaataa atgattgtga tgaatttagt atctctacaa actcatctct
    20701 tgtaacttct ctatagttat ctaaacacct atctcttaca tcagtttttt ctttttttgt
    20761 aactggcttc tctaataatt tttctttatc tacataaatt ggaatattaa tcattgatgt
    20821 ttccatttgt gtttcctcct tataaaattc tgttaaagac taaaacatac agataataaa
    20881 aacaaactct ttattactat atgttttagt cttatttgtt tactcaacct ttataccgtt
    20941 ccatgaaact atcaatatca gattttttaa atctaatgac cgtatcaatt tttataacag
    21001 gtaacccgta ttgagaaaca tattttctaa tcgttcctac tgatacacct agatattcac
    21061 ttgcctgctg atagtccata tactctagag tgactccaga aataatgtct tctagcatag
    21121 gctttagcac tgtaattatc tctttcactt gttgttcaac ttgtatagaa acaatgctat
    21181 caatgatttg tagagacata tttccccctc ctttcgtgat tgcttgaaca aattttctaa
    21241 gaattatctt cgtatttttt gctcaaaata aaagtatttt gttattaacc gattaatcaa
    21301 acaaaaaatg attaccagtt catcgacata cacataatac ctcgataaaa aagaggtgtc
    21361 aatatctttg taaaatttat ttacaacacc cctttttcga ggtatactaa ttttaggagg
    21421 tgtggtcaat atgataaaac gtccaccaat aaattattta gaacgaaaaa agatactcgg
    21481 aacaaaaata aaagctataa gaaagagtaa aaaattaaca caaccagcat ttggtcttat
    21541 gattaacaac ggtcaattaa ttgacaaaaa aactatctac gaatgggaga agggaaccta
    21601 tttaccaata ccagagcgat tatcccgaat tgctgatttg ggaaatatga gtatagagga
    21661 gttagtttgt ggcaatgtag aagaatatat tttgggaatt attctttata gagatagcat
    21721 tgtactagat ggtataacat ttccagataa aaacctgttc cagcatcttc gtcaacagtt
    21781 cccaccagta cactctaatt tagatacatg gctggataga tattccaaat tagaaccaga
    21841 gatgcaagaa tttattgcta acaagacttg taataaagtt aaaaatgaaa aaattagtct
    21901 tttcaatatc ttaaaaatag aagaattatt catcaatgct attgtagaag aatttgacaa
    21961 taacattctt ttcctcacta gcagtataga agaactacta gaaagaatgg tagatgaatg
    22021 gctacctatt caattgaaag acatgtctta tcccgaagaa gctgtgagag aaattactga
    22081 taatataaac aagctagaac aaacgatttc atcaattggg aaaaaataca ctaagaaaaa
    22141 aatgaaggga ggtgatacca tctagtggta agtactcctt gtaaactaag aggagatgat
    22201 ttcatggcaa aaatatcaaa gtacaaaaag aaaaacggtc aagtggcgtg gatgtataaa
    22261 ggacacattg ccaccgatcc acgaactggt gaaaaaataa atactacgag aagaggtttt
    22321 agtagcaaac aagaagctca aaaagattat gacgagtaca gacatcaaat attatacggt
    22381 gttaaaaaga aagcacctga tatgacattt gaagacctgt ataatgaatg gataactcat
    22441 cagcgtacca gtgttaaagc ttcaacaatc gcaatctcag taagatacgc aaataatcaa
    22501 atacttccag catttggtaa gcttaaacta tcgaatatct ctgtcccata ttgtcaaaaa
    22561 gtggtagatg aatggcacag taaatatgaa agttacgatt atatgagaaa acagactgca
    22621 caaattttac gctacggggt tgcaatgcaa tatattgaca ataatcctat ggaaaaaaca
    22681 cttcttccac gaaaaaaaga gtatgagaaa aatcgtaaat tttactcaaa agaggagctt
    22741 aataatttac tggatgcttt taaagatttt ggtaacatga aacaatacgc cttcttcaga
    22801 ttattggcat acacaggtat gagaaagagt gaagtactcg ctttacagtg gaaagacata
    22861 gacacgttta ataaagaact acatgtcaat aaaactcttg ctgtagatga atttggtaaa
    22921 gttataattc aatctccgaa aacaagagct tctagacgag ttatctcttt agatactgag
    22981 actctttcta tcctcaacaa ctggaaatta cagcaaaaag aagagtattt aaaacttgga
    23041 tacaatacta gctctaaaga gcaacatgtt tttacaacag ttaaaaacac tctatacatt
    23101 ccaaacactg ttaatgattg gttaagatat attttgaaaa aatataactt gcctcgtatt
    23161 acacctcatg ggtttagaca tacacatgct agtttattat tagaagcagg agaatctgtc
    23221 aaggtagttc aacaacgatt agggcatgaa aatagtaaag tgacattaga catctatgca
    23281 catattacaa ataatgcacc taagaaaaca ggtcaagact ttgctgatat gatggctcat
    23341 cagtaaaaga gctggtcaaa atctggtcat ttctagtata caggcaaaac aaaaaagcta
    23401 gaacccttat atatcaaggg ttctagctcc tataacaggt ttacccaaca ctgccttcca
    23461 tctcataact gatcaatcga ttgagttcga ctgcatattc cattggaagt tctttggtga
    23521 atggttcaac aaagcccatg acgatcattt cagttgcttc agattcggtc aggcctcggc
    23581 tcatcagata gtagagttgt tcttctgaga tttttgagac tttggcttcg tgttctaaag
    23641 agacttggct gttgtggatc tcattgaatg ggatcgtatc ggatttcgac cattcgtcca
    23701 tgatgatcgt gtcacattcg atatgagaga tcgaacccgc actgtttttg gcaaaggtta
    23761 cttgtcctcg atagtttact tctccgccgt cttttgaaat tgatttagag acgatagagc
    23821 tagatgtatt tggtgcattg tggatcattt ttgcacccgt atcttggatt tggtttgctc
    23881 ctgcaaaggc gatggagagc atggtgcctc gtgcaccttt tccatctaag taaacacttg
    23941 ggtatttcat cgttgttttt gcacctaggt ttccgtcgat ccattcaacg gttgcgcctt
    24001 cgtatgcttt tgctcgtttg gttactaagt tgtacacatt gtctgaccag ttttggatcg
    24061 ttgtgtaacg gcaatacgca tcttttcttg taaagatttc tacgatggcg gcatgcaggc
    24121 tgttacttga ataagtaggt gccgtacaac cttcgacata gtggatgctt gctccttcgt
    24181 caacaatgat cagcgtacgt tcgaattgcc ccgtgttttc cgcattgatc cggaagtacg
    24241 tttgtaatgg aacatcgact ttgacgcctt ttggcacgta aataaaggtc ccacctgacc
    24301 atacggctga attcagcgct gctaatttgt tgtcggttgg cggtacaagt tttgaaaagt
    24361 actctttgaa taattcaggg tattctttca aagcagagtc agtgtcagta aagacgattc
    24421 ctaacttttc gaattcatct ttcatattat ggtacacgac ttctgattca tattgtgcgg
    24481 aagcaccggc tagataagct cgttcagctt ctggtatacc aatcttttca aatgtatctt
    24541 tgattttttc tggtacgtct tcccagtcac gagcgggttt gtcacttggt ttttggtaat
    24601 atttgatggc atcgaaatcg atgtctgaaa ggtcggggcc ccatgtttgc attggcattt
    24661 tgttaaatgt ttctagagat ttcagacgga attcaagcat ccattctggt tcgcctttga
    24721 ttcttgacat ctcacggatc acttcttctg tcaagccttc tcctgtactg aaaaccggtt
    24781 cgacatcatc gtgaaacccg aatttatatt cttctaattc tggtacgccc atgttctcac
    24841 tcctcttcct tgtggtaatg atggaaagct gcggtaccat cgttttccat tgcttttcct
    24901 agtgctttcc aggcaagtgt cgcacatttg atccgagcgg gaaatttagc tacaccacca
    24961 agcatagcag catcgcctaa ttggtcggga tctttgactt cttttccttg gacaagctgt
    25021 agaaagtcta cagttaaatg ttctgcttct tctattgatt ttccgatgac ggcgtctgtc
    25081 atcatcgagg cacttgccgt actgatggag cagccactgc cgtcaaaggc gatatttttg
    25141 atgattccgt cttttacatc gacttgcaat tcgatcacat ctccacatgt ggggttgttc
    25201 aattcgatct tgcttgtcga gtcagtcaag cttccacgat gatgcggatg ggaagaatga
    25261 tccaagatca cttgacggta taaattgtct aatttagata gtcccatgtt ggaaaaactc
    25321 ctttgttgcc atgattgctt caactaaacg gtcggcgtct tgcgttgtgt tgtagaaata
    25381 aaagctcgcg cgagcagtcg ctgatacttc aaggtacttc aatagcggtt gcgcacaatg
    25441 atgacctgct ctgacggcta ccccttccat gtctaaagct gtcgcgacat catggggatg
    25501 taacccatcc aaattgaatg caacgactcc tgtccgaaaa ttcgggtctt gtggaccata
    25561 aacagtcaat ccatcaattg cttgtaattt tggcaacaca taagcggcta gttcttcttc
    25621 atatcgatgg atattgtcca taccgagttt ttgcaaataa tcgattgcat ggcctaatgc
    25681 gatagcgccg gcgatatttg gtgtccctgc ttcgaatttc caaggtagtt ctttccatgt
    25741 actgtcgtat aattcgacaa aatcgatcat ttcgccacca aattcaacag gttccatttc
    25801 ttctaaccat tttcgtttac catataaaac accaatacct gttggtccgc acattttgtg
    25861 tccgctgaaa gcaaagaaat cacagtctag tgcttggaca tcaatggcca tgtgcggggc
    25921 agattgagca ccatctacta cgatgacccc gccgttttca tggacaagtt cagctaattc
    25981 ttgaacagga ttgaagacac ctaagacatt ggatacatga gcaatggaga cgattttggt
    26041 tttgtccgta atctttttcg ctgcatcctc catatccagg aagccttctt ctgttagttc
    26101 gatatatttc aagacagcac ctgttcgttt tgccaactgc tgccacggga taacattaga
    26161 atgatgttcc atgtaagaga gcactatctc gtctcctgct ttgatatagc ggtcgccgaa
    26221 ggttctggct acccaattca agcttgtcgt cgtaccacga gtaaacagca cttctgctgt
    26281 ttcttttgca tggatgaacg cccgtacttt ttctcttgct tgttcataat catgggtcgc
    26341 gcgttctgct aacgtatgga caccgcgatg aacattggcg ttatcgtgtt cgtaatagta
    26401 cgctaatgcc tggagtactt gttttggctt ttgggtcgtc gctgcattat ccagataaac
    26461 taaaggttca tcattgacgt cttgaaataa gataggaaaa tcattgcgta gctttttagc
    26521 atcgatcatc cattcaactt cccttcgatt acttcgacta attctttccg aacttgttct
    26581 acagggattg ctgttaagac agaaccgagg aatcctcgaa tcactaagcg ctctgcttct
    26641 tctttatgca atcctctact catcagatag tacatttctt ctggatcaac tcgtcctaca
    26701 ctggcagcat gtccagcagt tacttcgttt tcatcgatca aaagaatagg attcgcatca
    26761 ccacgtgctt tatcagaaag catcaagaca cgactttctt gttgggcatc tgcacctttt
    26821 gcccctttca agatgtggcc gataccatta aaggtcaatg ttcctttttc tcggatcact
    26881 ccgtgttgca aaatatgccc gatcgtatga ggggctttat tggttactcg tgtatcgatt
    26941 ccttggattt gtctgcccga gctgattgcc acgattttga cttctgcgtg tgcaccttct
    27001 cctgctaaat ctgagtcaaa gtcagcgatc acatgaccgt cattcatgac accaattgcc
    27061 cagtcgacag aagcatctcg taaaatgtgc ccacggcgat tcatataaga agtaatattt
    27121 tctcctaatt gatctacggc tgaatatttg atttttgaac cagctttagc gatgacttcc
    27181 acgatgatat tacctgatga ttttgctact tgttctttgg ttgtctggaa acgttccaga
    27241 taagaaaatt cactatgttc atctgccacg atcaacacat gcttgaagaa gtgctcatcg
    27301 gatgcgccat cttgaatgaa taaggactcg agtggttcat cgatcacgac atttttaggc
    27361 acatacagga aaataccgct gttcataaaa gctacatgga gtgcagtcaa ttggtcttcg
    27421 ttcatgttta ctgctttttt catataatat tcttggacta gttctggata ttcgatcatt
    27481 gcagtgaaca agtcggtaaa aatgactcct ttttctgcta attccacagg cagttgttca
    27541 aaaatcgtcc atgaaccttg ttggacaagc acaggattgt ctttcattgc atcaaatgcc
    27601 ggaatcgtgc ctgtttcact gatggtttgt gtttctttca catcaaataa cgaccagcga
    27661 tggaatttca cccgatcgat atgcggcaat ggcagttcat ctgctttcgc tagtgcgtct
    27721 tgacggaagg ttctcatcca atcaggttcg cctttactta aagaaaaatc atttaccgcg
    27781 tcaagataat cgagccagtt tttttctttc attcttgctc ccccttacgc ttcttcttct
    27841 ttatagtcga ttcctaattc tttactgata ccagcgtagc cttctgcttc cagacgttta
    27901 gctaggtcag cattccctgt catgactact cggccttcca tcatgatgtg aacgacatca
    27961 ggtgtgatat agttcaataa tcgttgatag tgggtgatga tcaatgcacc gaaattgtct
    28021 ccgcgcattt catttactcc tttagcaacg actttcaaag catcgatatc cagacctgaa
    28081 tcgatttcgt ctaaaattgc aaatgtaggt tctaacatca acaattgcag gatctcattc
    28141 cgtttctttt ctccgccaga aaaaccttcg ttcagataac gttcagccat ttcttctggc
    28201 atatttagta aagccatttt ttcatctaac tttttcaaaa atgccataac agaaattttg
    28261 tcgttttcat cacgtttcgc attgatcgct gcacgcatga attccgcatt cgtgatacct
    28321 ggtatctcac ttggatattg catagctaaa aataagccaa gtcgcgcacg ttcatctact
    28381 tccaagtcta aaacattttt cccgtcaaac aaaatttcgc cttctgttac ttcatagttt
    28441 ggattgccca tgatagcggc agataaggta gattttcctg tgccgttagg tcccatgatg
    28501 gcatggattt ctccggtttt cattgttagg tttacgcctt taaggatttc tttttcctcg
    28561 atcgacacat gtagattttt tatttctaag acagacatgc attatacccc caaattctct
    28621 ttcgttctca ctcattttag actaattgag aatgaagcgc aatgaccttc cttactaaaa
    28681 tcaaatatct tttatttatt attaaacaat tttgatttct aaattagaat aggtataaaa
    28741 aagatgagaa ataagccatt acagacttat ttctcatctt ttttgttcca taccttattt
    28801 tgcatcagcc tttactggtt taacagagcc gccccatttg tctgtgatcc attcttggac
    28861 ttctttgcgg tgaagcactt caatcagttt tttgattttg tcactgtctt catcaccttt
    28921 acgagtcgca ataatattca cgtaaggaga gttgtccttt tcaagcaata cggcatcttc
    28981 taatggattc aaccctgcgc cgtaagcgaa gtttgcgttg attgcaacta ggtcaccttc
    29041 atcattttgg tacgtagaag ctaaaagtga tgggtcgatc gtatggttga acttcaagtt
    29101 cttagggttt tcttcaatat catcgaatgt tgctgtttcc agatctactc catctttgac
    29161 tttgactaag ccagcatctt gtagaattgt gatgatgcgt ccccagtctg attcagaatt
    29221 tgaagtaatg attgttgcac catcttttaa ttcggaaaca tctttgactt ttttagagta
    29281 caagcccatt ggttcgatgt ggacagcacc ggcattgaca aagtcatatc ctttttcttt
    29341 gatttctttg ttcaaataag gaatatgctg gaagtaattg gcatcaatgt cgccttcttc
    29401 caaagattgg ttcggtaata catagtcatc gaatttgacg atttcaagat cgattccttc
    29461 atctttcaat aatggtttca catgttccaa aatctctgcg tgcggtgtcg gtgaagcgcc
    29521 gactttcaat gtcgtgtcgt ctgctttatt tgctgaatct ttgctgtcgc tgttgttacc
    29581 gcatgctgct aatcctacag tcagcaaaag cgctgctgca aatccaaaaa ttttcttttt
    29641 catatcctac atccccctat atcctattat cttttgtctg ttttcttagt taagaaatca
    29701 ccgattcctt gaacgataaa tacgattagt aaaataatta aagtcgcaac gaatgtcact
    29761 gttagattac cacgctggta gccttcctgc caagcaagac ctccaagtcc acctgcgccg
    29821 atcgcgccgg ccatcgcagt aaatccgatc atcgagatcg ttgtaactgt taatccagaa
    29881 atcaatgcgg gaatactttc aggtatcaag accttccaga tgatttccca gtaacttgct
    29941 cccattgcat ctgctgcttc cagtacacca gggctgactt cacgaaaagc aatctctact
    30001 agacgggcat aaaatggtgc tgcggataaa acaagagctg gaatggctgc ttgcgcacct
    30061 agcatagtgc ctacgattgc tttagtaaat ggaatgatca aaaccatcag gatcataaat
    30121 ggcgttgacc ggaaaatatt actgatgatc gatacgattc cataaatgat tcgagcatac
    30181 ggtttgtttt tgcgtccaat agagtaaagg atcaatccca aaactaatcc gatgatcgtc
    30241 actaagacca ttgagattaa tgtcatatat agtgtatcaa ggatagcctg attcatcgtt
    30301 tccgggttga tttgtttaaa atctagatat gtttctgaaa agcttttatc cacgatggat
    30361 cacctcaatt cctactcctt gttctttgat gaacacttct gcttgatcta attctttggt
    30421 ttcaccagtc atcaagacag tcaatgaacc aaaggaacct tctttcactt gtttgatctt
    30481 tccatacaca acgttgacat cgatgttata gcgtcgaatc gcttgggaaa tgactggctc
    30541 gttggcattt ctttcgctaa aggtcaaagt tgccaaacgg ccgcttggat tttctttgat
    30601 gagttcagct aatagttctg tcgaatcagc ttctggttcg atgtcttgtt gtacaaagcg
    30661 tttggttact tcttttttcg gttgtctgaa gacagtcaat acgtctcctt cttctacgac
    30721 tttccccaac tccatcacag cgactttgtt gcagattttg cggatcacat tcatttcatg
    30781 tgtgatcaag acgatggtca aattcaattt cttattgatc gctaacaata agtctaatac
    30841 ttcttctgtt gtttgcgggt ccaatgcgct agtagcctca tcacaaagca ggatctcagg
    30901 atcatttgcc aatgctcgtg cgataccgac gcgttgtttc tgtccgccgg aaagttgtga
    30961 aggatatgct tgtccgcgtc cttctaaccc gactaaacgc aacagttctt ctgcccgttc
    31021 tttacgtttg ctctttggta cgccagctaa ttccagcggc agctggatat tttcaagtac
    31081 agttcttgac cataacaggt tgaaatgctg gaagatcata ccgattttct ttcggaatgt
    31141 acgtaattct ttgtttttta attttgtaat atcttgatcg tttacgatca cttcgccgct
    31201 cgtgggaagc tcaagtccat tcaggagacg gactaatgta ctttttcctg cgccagaata
    31261 gccgacgatt ccataaatat cccctttttc aacgtttagt gaaacgtcat tgacggcttg
    31321 gatgtttccg tttttcccat tgaatgtctt tttgacattc gttagttgga ttaatgacat
    31381 gccattcaca tctttctctt ataatttttc aaacaaaaaa gccttcgccc tcttgcctta
    31441 agcaaaagga cgaaagcttg aacttccgtg ttaccacctt gatttaccgt tacttcgcaa
    31501 taacagcctc ttccagtact tggacttagc ttctttccgt atactgtcgc gctgtaacgg
    31561 gcactcccgt agtaagtttg cttacgctcg cttactctgc tctaagacca tcttccatct
    31621 cattttcgtt acccattttc agcaaacagg gctctcttca aacgtccgtg acatgtactc
    31681 ttcttttcaa agctttctcg tttcatatag gattgcttat gattatagca actggaagaa
    31741 tcagtgtcaa cttttttcaa gtgattttct gattttataa ttcgtcaaat tcttttggat
    31801 caacatcttt gaaacttaag atccacgcat tcatttcatc tgaatcattc aagatattga
    31861 tatcttcacc gattttatca ttaacagaag aaactgtacc cgttagcggg ctggcaaatt
    31921 cattgaccgc tttttccgct tcaacttcga tcagaggttc atcttttttt agcgattgtc
    31981 ctgcttttgg cagattggca aacgtgatgt ctccaagttc ttcttgcgct tcatttgtca
    32041 aaccaacaca gtattctttt ccattaaata agatccaaag gttgtccttt ttcttcaaat
    32101 gcttgcctgc cattttatat cagttctcct tcataaattt tttcattgaa tccaattgca
    32161 acaagctggt cctctcgtaa gatcagtggt cgcttgatca gcataccatc tgtcgataag
    32221 acttggctcg cttttgaagc cgtaaactcg cctacttgat ctttcagtcc aagttcccga
    32281 tatttcatcc cgcttgtgtt gaacaggcga cggattggta cttgactcgt ttctagccaa
    32341 gtctcaatcg ttgaggcctt cggtacttct ttgatcatat caacggtttg ataactaacg
    32401 ccatgctggt ctaaccacgc tttggctttt ttgcatgttg aacatttcgg gtaccagtaa
    32461 aaggtgtaca attttcttac ctccttgaag atcttgcagg tgcttcattt tggtatctca
    32521 tcgataatat caacccgata ccgatcatgt tccctaaaat cgaggatcct ccctgactaa
    32581 tgaaaggcaa tgggatccct gttaaaggaa gtaatccgat atttgctcca atattctcaa
    32641 agacatggaa cagcagcatc atgatcaaac cgcttgcgat ataggcgtaa aattcattat
    32701 tcgtatcgaa acacacccga atcatacgat agattaaaat aaaatacaag aaaatgacga
    32761 atgcaccacc gataaagccg aagttttcac cgataacggt aaaaatcata tcggactcac
    32821 gaacaggcac atagatattg cttacgttga atcctttacc aaacaagcca ccggtaccaa
    32881 ttgccaaaag tccttgggcc ggctgataac tcattcctga cgtatcatgg aaagggtcca
    32941 gccatgaatc aatacgtgca aactgataag atttgaatcc aactttataa agcaagtctc
    33001 ttccgccttc agtcgtaacc aagaagatcg ttcctgctcc aacgactact gccaagatta
    33061 ctacaggtgc gatgatgcgc caagagattc cagacatcag gaaaatcccg ccaaagatcg
    33121 caagaaagac aagcatcgtt ccaaagtcat cttgggccat gatcaatgct aaaaccggta
    33181 ttgtcacgat caagagcttc ccaatcagcc aaaagtccga tttcatcgtc cgttctttta
    33241 cttgcgtatt atgtttagtt acgatcagtg ccatcatcaa gatgtacgca atcttcatca
    33301 actctgctgg ctggaaagta aacgcaccga atcgaaacca gtttttagac cctgttgaag
    33361 cagctaaatt ctgatcatag aatttgagca agagtcccat taccactaac cccaaaccat
    33421 aaaggtaagg agtcagtttc cagatccatt tggaattcaa atgcatgatg acaacgattg
    33481 ctgccgctcc aactaaatac cagacaactt gcatccctac gcctttcaag actgctggat
    33541 tgttcggatc atggctaagt gctacatata atgagagcag accaatcaaa cataacagaa
    33601 agactggtaa aatcacgcca taatcaatac gattatcgtt cgaagctttt aatttttttt
    33661 ccatgtttca tcccttttct taaaaaccat actgctgatt attatagcgg tccagttaga
    33721 taatggaaag tctttccata gacatttggg aaaaattaac tttccgtttg tgcagttgct
    33781 tgagcaaatg cagtacaaaa gcctactgct tatctttagt gtatcataga actttttttg
    33841 atacatgcaa ttatctacca gctgagattc tcctcgctgt gagaagtttc tgtgctttca
    33901 ttgtatcgaa ggatctcttc ggcaatctct agcagctgat cagaaaccag attggttcgt
    33961 tggatgaaat aaaaatatcg atggaaattc aacggagtca ttggcacatt ttctggaaca
    34021 gagcgcttag acaaaatcga gcgaccgatt ccttccttca gcaacgcaac aattacatcg
    34081 ttacttttca cgatcatctt cttatcttgg atattcatct cttcaaaata acgctgcgtg
    34141 taatgaaaaa caccagagtt tgcttctctt acaagccaca atttgctttt tgggtcccca
    34201 gcgatgacta gctggtcttc catcaaagag tatctttgta cgccggaagt ctctaatggc
    34261 ttttcgataa aaccaaaatc ggattcatgt ttcgctactt gttctaatga ttcatgagaa
    34321 ttcgtgattt cgatctcaaa atgcacttta ggaaaccttt tgatcagatg tttcatcaac
    34381 tgaggcaaaa gatagacagc aaaggtgtgg gaagcaacga tccgacatac ttcttcttca
    34441 ttttgttcat tgagcaattt ttgctgagtt tcttcccatt cttctaacaa aaccagtgtc
    34501 cgttcatata ataagtcggc ttgcttagtt ggaagcatct cttttcttcc gttacgttga
    34561 aaaagatcga tattcaattc ccgctccaac tgtttgattt gattcgagac tgctggttga
    34621 gataaaaaca gtacttctgc tgctctggaa aaatttcttg tttcatatac tgctcgaaaa
    34681 gtcgttaata acttaaacat ggcaccactt ccataacttt ttatgataat tactataaaa
    34741 actatttgat ttaaatatac aaaaaaccat ctataataga aatgtacaac aaaacagttg
    34801 ctgatccaac tagtaactta gatgaagaca atcagctgtc tgcttgctcg taatcataca
    34861 ttcctattca ttttacaatg tattcgttca tcttggtact aaaatctatt aaataaaaag
    34921 gagaatatta tatatgaaga actttttgaa aattattccg atcccgatct gcgggttgat
    34981 ccttgggtta gcttcccttg gaaatctgtt taaagactat caccatgttg ctttaggcaa
    35041 tctaactggc ggtatctcta tgattcttat gatattcatt tttgttaaat tgtttatctt
    35101 attcgaacac acgaaacaaa cgttgcatga tccaatcatc gcctccgttt caccaacttt
    35161 tacgatgtca ctcatggtta tttgtactta ttttgtttca tatgaaagta ttgcaccaat
    35221 tgtcaaattc atttggctgt gcgctgttat cttccaagtg atccttgtct tttatttcaa
    35281 ttatcaccat gttatcaaag ctgatctttc aattgaagca atttatccaa gctggtttat
    35341 catttacgtt ggatttgggg tcatcactgt aactgccggg aacttcttcc cacttattgg
    35401 aaaaattttc ttttggattt cattgatctg ctatgcgttc ttattgccga tcatcatcaa
    35461 acgtgtcttt ttcgtaagaa atatggctca tccgacacgt ccgctgatta cgatcgttgc
    35521 agcacctggt tctctttgcc taacaggtta tcttaaaaac tttgctgaac ctaattttta
    35581 tcttgtcgta gcattgttcg ctttatctca agtattgtat ttcgttgtgc tgtctatgct
    35641 tccacgtttg ttcaagcttc gtttttatcc aagctatgca gcctttacat tcccgcttgt
    35701 tatctctgca acagctatat ttactactgt tcattacttc aacagtttag gtatctatag
    35761 tagcgtattg gatttcttaa aagttgcgga atgtctgttt gcaagtgtag ttgtcttcta
    35821 cgttcttgct cattacgtac gtttcttaat taaagaacat agcaaacatg gaaaatttgt
    35881 ttctaaaaaa atcgcttaat aatcgattca ataggttgtg aaaaagctgt tctgcatcaa
    35941 gtaataagaa cggccaaaca aaaacagctg ttcatgtttt tgtactggtt gggcttatta
    36001 ccgcagatgc aagcttttga acaccgttta ccaagaggtc gtaaaagaag tggtcagctt
    36061 caagaaataa gaaggaattt acgaaaattg cttctcaaat ttttgtgaaa tttcggctta
    36121 tttccgtaga agctacttct ggaacaccgt ttattcgaaa caagaggtcg tacaagactt
    36181 ttgtcacgac ctcttgttct tttgtcaaaa tactggttta gtgctactat gttcgagtat
    36241 gcttttagta tttattgacg aaaggaaccg atcaaatgaa atcattgtca catccaataa
    36301 aatctgtaaa ggattcagcg gtccgcgaaa tcttacccgg tttactgctt tcttttgcca
    36361 tcgctgcctt cagcaggctt cttgctattt atctgccaca gttaggtgga gcgactattg
    36421 ctattttatt gggtatttta ttaggaaata ctttttttaa acagcctgtt ctagcaatcg
    36481 gcacaaaatt tgctgaaagc aaactattag aattctctgt ttttttacta ggtgcaactg
    36541 tcacagctca aacgattgct caaattggtg taaaaggaat tgtttttgtg ttactgcaaa
    36601 tgtcagtcac tatcatcggt gcttacttga ttggtaaaaa actgcaattc agcgatactt
    36661 cttctttgat gatggctgga ggaaacgctg tttgtggttc ttctgctatt gcttcaatcg
    36721 ccccttccat ccatgcgaaa gaggaagaaa aaggacagat catcacacta gtcaatctac
    36781 tgggtactgt gatgatgttg actctccctt ttcttggatt acagttgttt ggtggaaatc
    36841 tcattgaaaa aagtgcactt ttgggtggta cactccaatc tgttggtcaa gtagtcgctg
    36901 gggcaagctt acttgacaat tctgttgtcg aattcgccat gctatttaag attctacgta
    36961 ttatgatgct cgttgttgtt gtctatctgt ttgaaaaatt catgcacaag aaacaaccag
    37021 ctctgtttga aacgccaact gatacgcaga aaaaacgaaa attaccgctt ccttggtatg
    37081 tattagggtt tgtgatcttt tgtttggtca acagcttgtt ttctttacct gtagttattg
    37141 accaatcggc acattttatc agcagctggt ttgagatcac tgctttagcg gcaattggtc
    37201 tgcgtttaga ctttgcaaaa ttcatgaaag aaggtacacg cttcttatct tatggattag
    37261 ctgtcgggct tctccaaaca gtgatggctt tactatttat ttggctgatc aaagtttaga
    37321 atgaacatga aaaaacagtt gtgattctcg catggaacaa tgtccgaatc acaactgttt
    37381 ttaattttgc agatatcctt ctaacaacaa caattggcgt ttgatttcaa ccccatctat
    37441 tgcgtttccc atatatcctg tcagttttcc attttgcccg atcactcgat gacaaggaat
    37501 aacgattggc aatggattgg ttcgatttgc ctgcccaatc gctcgcacag ctttcggact
    37561 atcaacagca acggctactt ctttatacgt tcggatttct ccataaggaa tggtcgacaa
    37621 agctttccag acattttgct gaaaaggcgt acctctcttt atagataaag gaacatcaaa
    37681 ttcttttctt tttcccgcaa aatattcttc aaactgttct tgtgtgcgcg ttaaaattcg
    37741 ctgattcgct gattcgcttt ctgaaattgg ctgaaaagat acagcagtca atccggattc
    37801 atctgcatct aaccataaaa agccgatagg tgtgtgtatt ttcattttgt ttgctcctag
    37861 tcaatagact ggaacttcct cctttttctc tatccaaaac tacttgccaa ctaataaaaa
    37921 ttgttcttaa aagtttgata aaccgaggaa acatggtaaa ctaaatacgt tagtttacaa
    37981 aaagaatacc tgttctttta cgtaaaatca aattttaaag gtgttattta aggtttatta
    38041 aattttgaat gtaaaccata tataaacata cgattgaaag gatagaaacg atgaaagtat
    38101 caattgttgt cccatgtttt aatgaagaaa aaactgttcc tctttttttt gatgaggttg
    38161 aaaaattcaa aggtgcccat gagttcgaat atttgtttat tgacgacgga tcaaaagacg
    38221 gtacgttagc agcaatcaag aagctagcct cagcttatcc ttatgtccgc tttgtctcat
    38281 tttccagaaa ttttgggaaa gaagcggctc tgtacgctgg attgcaagct tctacaggag
    38341 atttagtgac cgtgatggat gttgatctgc aagatccgcc cgaactgctt cctgagatga
    38401 tcaaccggat cactacttct gatatcgatt gtgtcggcac ccggcgttcg actcgtgaag
    38461 gcgagcctgc gatacgcagt ttctttgcga aaaaattcta ccagttgatc aataaaatca
    38521 gcgatacaga aatggtcgat ggcgctcgtg atttccgctt gatgactcgt caaatggtgg
    38581 atgccgtcct agaattaaca gaatacaacc gattttcaaa aggattattt agctgggtcg
    38641 gatttaaaac agaatatatt tcttatgaaa accgcgaacg tgtggctggc gaaacatctt
    38701 ggtccttctg gaaattattc aactactcga ttgatggtat cgtgaacttc tcggatgcac
    38761 cgttaacgat tgcttcattt atcggcgctt tgtcttgtgt cggttctggt attgcaattt
    38821 tgttcattat tttgcgggca ttgttgtttg gtgatcctac atcaggatgg ccttccatgg
    38881 tctcgatctt cctgttcatt ggtggaatcc aattgttatg tcttggaatc atcgggaaat
    38941 atattgggaa aatcttctta gaaacgaaac agcgtcctgt ttatatcata agagaaacag
    39001 aaaaagtgaa gccaaatgaa ttgaagcctc accaataata tacgtcaaat gaagtaaaca
    39061 tttttttaaa tgaaaaagga ctgtgacaaa agtcttgtca cagtcctttt ttccgaataa
    39121 atggtgttcc agaagtagct tcttcggaaa taagccgaaa tttcacaaaa atttgagaag
    39181 caattttcgt aaattccttc ttatttcttg aagctgacca cttctatcac aacctctttc
    39241 atatcttatt acttcttcat tgctgctttt agtgctgctg ctaatgggct ttcttctggt
    39301 tcttctgctt gtgcatattt tttcagcaag cgtcgttctt catgtttggt cattttcttc
    39361 ttctgctctt ttttatcaag caatttttct gtcgttccat cgtatttaca acggaaataa
    39421 gcaccgtttt taccttcgat gatttccatt ttccggtgac attgcgggca tcgatgatta
    39481 gagacttttg gatcttttct tctgcggtag ttgcaatctg aattggtgca gacatagatt
    39541 ttgccgtcac gtgtgttttt ctcgcgcaga ttggccccac attctgggca tttcttttgg
    39601 gtaatcgaga aatcttgata ttcttgtttg cttgatttga tctcattcac caagcgtttt
    39661 gtttcttttt cgattccatt caagaaggtt cctgcttgtt tctttcctgc agcaatagct
    39721 tcaaggtctt tttcccagct ttctgtcaaa tctggtgtta ctaaagaggg atttaccaat
    39781 actaataatt gcttaccttt aggagatact tgcagtcctt gaggggtacg ttccatcagt
    39841 tcagatttga ttagtttctc gataatctct gcacgcgtag ctggggttcc cagactgtat
    39901 ttttccattt gaccaagcaa gcttgcttct gacaatggtt taggcggtgc agatagttct
    39961 tttttgatgg cgaaatcggg attgattctc attccttttt cccatttgac tgtttccgtc
    40021 tcagtttcag tttcgccttt ccatcctgct tggacgacac gattttgccg aaaaatgaat
    40081 cgttctttac caaattcaac cgtaactttt gtttggctga ctttatgggg ttgagcaaac
    40141 agtcctaaaa aacgagagac aatcatttga tagatttttc gctcttcatt acttaatttt
    40201 tcataacgtg ctctgttttc agttggcaaa agtgcatggt gatcggtcac tttactgtct
    40261 tggaatactt ttgtctgttg gacgatggct ccgtttttca aatactgctt gacctcagga
    40321 gcaaagtcgc tgactgcttg caatcgttct ttcatcgtac ttttcatgtc atttgtcaga
    40381 tatttgctgt ctgtacgcgg ataagtaacg atcttatggg tctcatacaa actttgtaca
    40441 agacttaatg ttttctttgc agaatagcca tagcgttgat tggcttctct ttggatctct
    40501 gttaaatcat aaggcaatgg cgcagattcc gtttttaatt tttcttggac ttctgtgaca
    40561 gttcctttgc ttgtactgat caattgaaca agtttttgtg cttcttcttg tgtttttaaa
    40621 gcaaattgat ttttttgaag cattttggct tgttcttttc cagcttgcaa cgtgatcgtg
    40681 aaatacgttt gtggacggaa ctgctcgatt ttcttttctt ggtctctcac taatgctagt
    40741 gtcggtgtct gcacacggcc tgctgataaa ttatccgcgt acttcacagt taaggctctg
    40801 gtcacattca atcctaccag ccagtccgct tttgcccggg caagagcaga ttcatacaat
    40861 gcatcatatt ctttcgcagg tcttagttgc ttgaatccag ttttgattgc tttatctgtt
    40921 tgagaagaga tccataaccg cttcactggt ttattgaaat gcacatactc taagatccag
    40981 cgagcaacaa gttccccttc tcttccggca tctgtcgcaa tgactgcttc tgagacatct
    41041 tttcgctgag ccagctgctt gattgctttt aattgatgtc ctgttttagg aagtggtttg
    41101 attcctagtt ttttagggat cattggcaac gtgtccattt gccagctctg ccattcctta
    41161 ttcagatctt ccggcatttt caatcctaat aaatgaccaa gggcccaagt aacgatcacc
    41221 ttgggtcctt cataataatt tttgtgcttt tgattagcac caagcacctt gcttaggtct
    41281 ttcgcaacgc ttggtttttc cgctagaatt agttgtttca taaaattcct ttctgctttc
    41341 tactgtgatg ggctgatgat ttttcaacaa cgcaagtccc ttgtattgct gtaaatcatc
    41401 gtcacactct tcacaccagc gctcatctcc gtcattccaa aaggcgctga gaaagttact
    41461 ttttgcattg atatattcat aattttgatg gatttcgttc cattgttttt cgtacgcttg
    41521 tcgtgcttct tcgaaagact cgaatgtttc ttcttcttca atatcttctt cccagtcttc
    41581 aaaaaaccac caaggctcat tgtccccgaa catggtaatt acttgataca tactcgtgct
    41641 ccttctttca gcttttctag actcatctta gtcacttttc aagaaagttg caagaatttt
    41701 ctcttataaa agggtcattt aatgaacatc ttaaaattgt tacaaatgaa tctgattgtt
    41761 taaggcaaag tagcgataaa gttattgatc atccaaaaat agctgtcttc tggatcgatt
    41821 gttggttctt ttgtaaagta tcctaaaaaa cgtaaggaaa gataaccgtg gatcatacta
    41881 cgaagttccc tgcttcgatg aactttttct tctttcgtta attgaaaagc ctcaaatatc
    41941 tgcaaaatga tctgattcgt ttcatggatt ccatctaata aaacagcttc attggtatgc
    42001 ggtacactga tcagtaactc atacactgct tgatttgaaa aagcaaagga tcgataagtt
    42061 tctgcataga tctgcagtgc ttcctgacca ctttttccca caagagcccg tcgcagctgg
    42121 tcattaagtt cctgcagaag tttcgctgtt agcgctgttt tgacatcacg aatatttttg
    42181 aaatggttat acagcgaggg agccttgata tccaagcgtt tggctaaatg ctgaaaggtt
    42241 atttgctgaa catccatctc ttctgctagt tctcgaaagc agtcgatgat tttctcttga
    42301 gacagatttc tttttttcat ttccatgttt cctctcataa aataaatcct tcactctttc
    42361 agtttaccac gaaaaagaaa gagaaaaaag agactttcat tgataaacta catattgtag
    42421 tttataataa agagctgtag atgaaaattt tcagaaagaa ggagtctaat tggctgcaag
    42481 aataaaggaa aaattattta ggaaaagaga aacttgggaa caaaacttgt ttgtcttatg
    42541 gtttggaaca tttatggctg gtatcggatt tagtttagtc atgcctttta tgtcacttta
    42601 catagatacg ttaggtaatt atagtacgtc acaattgaac ttttggagcg gattgacttt
    42661 ttcatctact ttcttggtga ctacgcttat ctctccttgg tggggaaaat tagccgacca
    42721 aaaaggaaga aaattgatgc tgttgcgtgc ttcattagga atggcaatcg tcatttcttt
    42781 gatgggttgc gtgactagtg tgtatcaatt agtcgcattg cgtctgcttc aagggatttt
    42841 ttctggttat atcagtaatg ccactgccct tgtcgcaact gggacgccaa aagaaaaaag
    42901 tggtcaagtt cttggaacct tagcaactgg ttctgttaca ggaacattac ttggaccgct
    42961 tcttggcggg atctctgctt cagcgtttgg ctatcgccct acctttttca ttacagggat
    43021 catcttattt ttcgtcttct tgttgagtct gtttttcgtc catgaaaaat ttgtcccagt
    43081 gaaaaaagaa aacatggttt ctgccaaaca gattttcaaa gacttgaaat atccacacgt
    43141 cgtcatcggt atgttcgtca caacgatgat catccaagca tccaacaatt ccattagtcc
    43201 aatcatcagt ctgtacattc gccaattgct gcatggacat gggaatgtta cgttgatcag
    43261 cggaatcatt gcttcgatac ctgggattgc cactttgata gccgctccaa gatttggtcg
    43321 cttaggtgac aagattggga gtgaaagaat acttgcgatt ggtttgggtt ttgcgattct
    43381 ggtttatatc ccaatggcat tcgtcacgaa tgtttggcaa ttagctgcct tacgtttttt
    43441 gattggtatc tctgatgctt gtctgctccc tgctgtccaa gcattgatca caaaatattc
    43501 gcctcatcaa gctgctggac ggatcttcag ttataaccaa tctttccaag caactggtaa
    43561 cgtagtaggg cctatgatcg gctccagtgt ttccagtgca tttggttatc gcggcgtctt
    43621 tctttcgact tctcttcttg ttttggtcaa cttcttgctt gtacgacaca atacacaaga
    43681 gatccatcag caagaaactg cagaagaaaa agcttcagga gtctccatag cttcagggca
    43741 ctctccttct catagacaat aagcgtaaat gaaaaacact gcttgaacag ttgtcacaga
    43801 ctgtccttgc agtgtttttg tttaggcctg ttttttcaag aactcagata agaggaataa
    43861 tcccttttcc aaggtttctt ttttacaaca gtaacctagt cgggcatgct tcggtaaatc
    43921 aaaggcactt cctggtacta atagtactcc tgtttcttct aataaattga tacaaaatgt
    43981 ctggtcatct tcttcgatgg ctaatttaat gaaagaagta gagacgtaat tgggagcgac
    44041 aagttcaact ttcggttcat tggctaccca ttgttttaaa atcacaaggt tctctgtaat
    44101 gatctttttg tttcgcgcca atattttttc tttattcttc aatgcatgta cagcaagatc
    44161 atctgacagg actccgccgc aaatcatcgt gtagtctcga tactttcgaa aaacttctgc
    44221 caactcaggt ccagtagctg tccagccaat acgaatacct ggaatggagt aggttttgga
    44281 tagggaattg gttgctatac ctttttcata gacatctacg atcgacaaga attcaccttt
    44341 atccgttaaa ggcgcatata cttcatctat caatacatat gcatctactg tacgagcaat
    44401 ttctgcgatt ttttctaaag ttttccgatc tagcaatgtg cctgtaggat tgtttgcact
    44461 attcaaacag atgatttttg tttcaggttt gactaaggct tctagctgtt ctaaatcaaa
    44521 ctgccaatct tcttcttcct tcaaatgaac aaagtcaaca gcggcaccta aagatttggg
    44581 gatgtcatat aattgctgat aagtaggaag catcgaaaca acatggtctc ctgcttccac
    44641 taacgcgtat agagctaaaa gattagcacc agtcgctcca ttcgtttgta agatgttttc
    44701 cggatcgacg gtttgataaa gagaagcgac ttcttgtttg aaaacatctg atccttcgat
    44761 ccagccatag tccaatggtt cgtttttgcg tttttcgaaa aatttactta cgctagtccc
    44821 atctaagcca acgagttcgt ctaatgtcaa tgcttcgatc gagctttgtg caatatcata
    44881 taccgctttc ttttcccatt tatttagcca ttcttctaca ccgaaatttg cgattttcat
    44941 gtttctttcc cccttatatc ttgatccagc ctacagcaag caacccgatt gaaagcagtg
    45001 cggccacaca aatcagccca atcattactt tttcttttcc cgtaatttga tgtttggttt
    45061 cacgacaagc gatccagtag aagcaaaaac caggaagata ggcaatacta cataaaagga
    45121 cataagaaaa tcctgctaaa atgatgccca tcaattcaaa aactacagca atcccaccga
    45181 tcactacttg ttttttgatt ccttctttta aagaaaactg gacttgatag atcccgacaa
    45241 gtagataaca aatcaaaatt gccgctgtac ataaagaata ggcaaattga taggcataat
    45301 cagtaactaa gaaagtcaat aagaatagat tagtcaagat tgcagtaaca actaacgaat
    45361 aagttggggc atttttttta ttcgtttttc cccaaccttt cggcaacaga ccgtctcgag
    45421 ccatcaacat cgttgtttct gctgggagca tcgtccaaga caaccaagaa ccaatgatcg
    45481 aaataatcaa gccgatattg atcagcgctg ctccccaatt tcccacgatt ccttttaaaa
    45541 tatttgccat agcaggttgt gaaatagttg ctaactcttc ttgagataag acgccgtatg
    45601 gcaagatcga agcaaggata tagataaaca ataaacaaag cagaccaatg atcgatgctt
    45661 gctgggcttc tgaacgtttc ttcgcgcggt tggctaaaac acttgcgcct tcgatcccta
    45721 caaagaccca catcataacc atcaaacaac ctttaatctg caaccagatc gttccttgct
    45781 gccctgttcc attcactaga ttatcagata cgttacccca aaaatcagca gtgaatatat
    45841 tcactttaaa tgcgataaat acaaatatta aaaataggaa taatggcact aatttacaga
    45901 tcgtcacgat tgtattgatg acgctcgctc cttcaactcc attgtttact aataaagtca
    45961 gaccccaaat aaaaatactt gcaaataaaa tagaaggaac attttgtcca cctttgaata
    46021 tcgggaaaaa ttctcccatg gcgctcatca gcatcgttgc aaaagcaaca tttcccagcc
    46081 acgcagacaa ccagtaaccc caaccactga tgaagccacc taatttacca aatgaagctt
    46141 ccgcgtaacc gaaaatacca ccatctagat ctggacgctt ttctcctaaa tgattcagcg
    46201 ataataccaa agctaaaata ccaatcccaa cgattatcca tgaaaggatc gctggccctg
    46261 gagctgcaga actagccaga tcacttgtga tcccaaacac accgcttccg attgacgaac
    46321 tgacaaccag agcaaccagt ccccatttgc taatacccgt cgatttcttt tccatttcca
    46381 tcaccctcac ttataaaatt gaacaaatca cttgcaaaag attcccttct attttgcaac
    46441 tgctcttgct taacaaaaag caactttatt catattattg gatattatga actttttaca
    46501 caagtatttc aagtataaaa tgaataaaaa ttaattttat tgcaaaaaaa cagctatgct
    46561 atccaaaaga aaaggtgttt cttttgttag ccatagctgt tttgattcat ttaatatcgc
    46621 ttaaacgtat tgtaaaactt ttgtttcttg atatgcgtgg tcgatcaaac caccacccag
    46681 acattccatt ccatcataaa atacaactgc ttgtccagga gtgattgcac gtacaggttc
    46741 gtcgaatacg acttctgcac gattatcatc caataagcga actgtcacag gaacgtcttg
    46801 ctgacgataa cggaatttcg ctgtacactt gaattctttt ggcattggtt cattcgtcgt
    46861 aaagtggatt tcacttgcat ccaagcttgt ggcatacaat gcaggatgat ggaacccttg
    46921 ccccacatat aatgtgtttg tcgctagatc ttttcctaca acaaaccagg gttcttgcga
    46981 atctcctccg ccaccgatcc ctagtccttg acgttgacca atcgtataat acatcaagcc
    47041 agcatgttgt cctttgactt caccatcaag agtgaccata tttccttttt ttgctggcag
    47101 atagttgctc aaaaattgtt tgaagttctt ttcaccaata aagcagattc ccgttgaatc
    47161 ttttttctta gcagtcgcaa ggcctgcgcg ttcagcaatt gcccgtactt ctgatttttc
    47221 catgccgcct agagggaaca tcgtttttga aagctgttct tgtgataatt ggctaaggaa
    47281 gtaagtttga tctttattat tgtctactcc acgaagcatg tggaccacgc cgttttcatc
    47341 gcgagtgact tgcgcataat gtccagtagc tacataatcg gcgccaagat ccattgcata
    47401 atccaagaat gctttgaatt tgatttcttt gttgcacatc acgtctgggt taggtgtacg
    47461 tcctgcgcgg tattcggcta ggaaatattc aaatacacga tcccaatatt ctttttcaaa
    47521 attcacagag taataaggaa tcccgatttg agcagctact ttcgctacat ccttataatc
    47581 ttccgtggcc gtgcatacac cgttttcgtc cgtgtcatcc caatttttca tgaatattcc
    47641 gatcacgtcg tatccttgtt cctttaacaa aagtgctgtt acagatgagt cgacaccgcc
    47701 gctcatccct acgacaacgc gtgttttgct gttgtctgtc atgatatcac catcatttca
    47761 attagattct gaaacatcta cgagttgaag gtcgcaactt ttcagtattt tacattatac
    47821 gtcatatttc tgaaaatttc atcccttaat tatcaagtcg taaaaatact gttctactgg
    47881 acctattcag tacacaaaca tgatagtcaa ccaaaaaatc actcatcttt tgagcattcg
    47941 atataaaaaa ttggcatact cataaaaagg gccagccttt cggcaataag gaataatttt
    48001 ataaattgtg aaaaactatt tttcaaaatt gcttcttatc gcttaaagct gcacgtctca
    48061 tttacaacct tttcttttta gatgttatga gttgctcaga taagtgattt tgtttactct
    48121 aagaaaaaag ggaggcaaaa gatacatgaa ttactttatc agtgatatgc actttttcca
    48181 tgaacgctta ttaggaaaaa acgactttgc tccgcggctc tttgcaaatg tggatgaaat
    48241 gaaccaacag ttgatcacta gctggaatgc agtaataaaa gaaaccgacc atgtttatca
    48301 tctaggcgac cttgctatgc atccgcaata tgaaaaagca aatgcagaaa ttttggaact
    48361 ggtcactcaa ctgcaaggaa caatccactt gatcaaaggg aaccatgaca gtcgcgcttt
    48421 tttccgttat ttagaaaaaa atgatcctag gcttactgac ggaagtccca aattttattt
    48481 ttatgatgta ggtgccatcg ttaaattcga ccatcaacaa tattacttga ctcattatcc
    48541 gatgttgctc gggcctaacg acactatccg caatcttcat ggacatatcc atcattacag
    48601 cgtacctatc gagaacgatg tcaatgtagg cgtagacgca ccggaaagag aactcttaaa
    48661 ggaaaaacta ccatttggca ctccgttatc tgagcaacaa atcaaagaaa tctatgaagc
    48721 aaagaggaag tacgataggt cgtgaaaaaa ctgccctata tcaagtatta aacaaataaa
    48781 gataattact catatttttc atttgagtag gcttattgcc acaggaacat taggatcaga
    48841 aatggagttg taacaagact tctgtcacaa ctccattcca tactattcgt ctttttgctc
    48901 atggtgttct tttaccagtt ttttctgtaa ttctttatca taatttcggg cagctgacgt
    48961 taaaaataaa acgattccgc ataataaaat cccgattccg gaaaacaaga acattttttc
    49021 tacccctaaa cgatcagcta atggtcctgc aaataataat ccaattggac ctgccaggtt
    49081 catcaaagag ttgaagttcc ctaagacacg acctaaaaca ttcgattcat aactctgctg
    49141 gatcattgcc atcagcagtg tattgaaata tggcgttgca caacctgctc ctgcattcaa
    49201 gataagaaag tacaagaacc cttgactatc gtttggaacc aatccgcttg caccgatcgt
    49261 caggcccata atgatgtagg ctataataat aggtttcatt cggtctttcc atgttcctat
    49321 aaaactgatc agtgcaccgc ctaagagcat tccgactgcg tagactactt ccactgctcc
    49381 cgcctgtcca acggaaccac caaagtaatc tagcgtcatc aatggataca gactgattgc
    49441 tggcatgaac aacagcatca caaatgcacc attgatcgtt atgtaccata accctttatt
    49501 atccatcaat tgctgcagcc caaattttgc atctttaaaa atagtaagcg gaacttccaa
    49561 tatttcagga gaaacttttg ggatcttcac aaaaatcaat aagccgacac caaaaactgc
    49621 ccccaataca tctaataaaa taaggtaatt gacaggaacg actgaaaaca aagccgcacc
    49681 tagagctggc gcaatgatga aattcgctga ttggaccatt cctaactgtc cattcgtcct
    49741 tgttatgtga gaagatggaa cgattgtcgg cataatcgac tggatcgttg gcatttggaa
    49801 tgtttgtgcg accgaacgca taaacaaaga cacaaaaact agccaaatcg ggaaggattc
    49861 tgaaatcgtt ccgactactg ctaaaataag cgcgaaaatc gctacaataa tatccgtgac
    49921 aatcaaaaga gcttttttat cccagcgatc cactagcggt cctacaaatg ggcttagtaa
    49981 aaccatggga atcattccta gtaaagtagc aaaactcaaa attgtcgccg aaccggtttc
    50041 tcttgtcaaa taccagatga tcgcatattg gacgaccata ctagtgattc ctgacaaaaa
    50101 ctgtcccgat aaaaagaaca aataatttct cttccaattc gttaaaacga ccgactgttc
    50161 attttccata aacatccctc ttttcttttt cattttgtat agcgtttgca caacaatcat
    50221 tatacgggat tcttttttca aaaaatacct ttttccctaa ataacaatcg tttcaattta
    50281 aatttcttta cttagaaaca ataaatcagc aaaatattaa aaataacaac atgtgttaaa
    50341 tttaaaaata aaaaagacaa ctaatttgcg tcgtccttac aaagttagtc atctaacaat
    50401 aggccgtttc aaaactagtt gtctttttat atccacagat cattcgactt tttcgaataa
    50461 cccacggcta atcatcccat ccatcagaaa ataaaattta tcttggctca ttttctgttt
    50521 tggatctttg aaaatattga ctgctttcaa tccatttgct gtagtgatcg acattttcaa
    50581 tgtttgaata tcttttgata cagtgatttt taatttgaat ccttctttgc tttgcggcgt
    50641 ggcatctaat ggtcggatca attgataatt gcctccgttt gtttctgtaa atccattatc
    50701 gcgcaatgta tatctttttg catcaggatg caaacgatag ctaattggtg cgcccagtac
    50761 cgttgctgtt gtttcaaatg ccatgatttt cacctcgata aaattagttt ctctttatta
    50821 taaaagttta tcctgatttt tactaggttt ttcagttaag ttccctaaaa aatgaaggcg
    50881 ttctctcaga catctgttca tataagaatg acttcactag ttattttttg acagcacgaa
    50941 ctaattgatc aaggaaatac tggatgtcgt cttcggtatt tcccaaacca aagctgatac
    51001 ggatggattc ttttagtatc ggtgtatctt ctccatacat tgcttctaat acgtgtgaag
    51061 gctcgatatt tcctgctgta caagctgaac cagtagaaat agcgacccca ttaagatcaa
    51121 gcttcatcag tagcaaatca tttgcttcgc caattaagcg aagattcaac acatgaggga
    51181 gtttattcgt taaatcacca tttacttgat aagggatttc gtttgcttct aatgtatcaa
    51241 gaatcaattg ctggaatcct ttatatttgt tgttacgtgc ttcacgttct tcaggtgaca
    51301 gcagttcaac tgcttttgcc ataccccaga tccctgctaa attttctgta cctgcacgcc
    51361 gcttttcttc ctgctccccg cctaaaagca atgcagggat atttactccg tctcgtttat
    51421 ataagaaacc gacgcctttt ggcccattga ttttatgagc agagatactt aataaatcga
    51481 ttcctaattc ttctggatgg atcgtttggt ttccgtacgc ttgtaccgca tctgtatgga
    51541 aataagctgg atgatccgct aaaagttcac cgatttcttt gattggcatc aaatttccga
    51601 tttcattgtt cccgtacatc acagagacca agatcgtatc ttctcgtaac gcttttttga
    51661 cctcttcgat cgacagattc cctttttcat ctacaggcag atatgtaacg tcaaacccct
    51721 ttgtctctaa atatttcatg gtattaagaa cagcaggatg ttcgatagct gtagtgatta
    51781 gatgtctgcc ttctttttga cgcgagaacg ctgtttctaa gatagctgta ttatcccctt
    51841 ctgttccccc actgttaaag atgatctcgt gaggttttgc ttgcagactg tctgcaatga
    51901 tttgtcttgc tgtttccaat ttttcatgcg cgtggcgacc aaatccatgt atgcttgaag
    51961 gatttccaaa cgtgtcttgc atgattgccg tcatcgcttc aattacttgt ggatgcatgg
    52021 gggtagttgc cgcatgatcc agataaatag ttttcacttc attcatccct tccaaattat
    52081 tgctaggcac attctagcat aaaatagcga acaaaccaaa gaagagctca tttttgtcta
    52141 gaggacgttt catgggcata gaaaaaagga gctgtgacaa aagtcttgtc gcagctcctt
    52201 gaagctgctc acttctgtca caacttcttt ccctcttttt tttgtttatt cgaattcttt
    52261 ttcttccaga cggaataacg gactcatcgg tgtattttca tggatgcgtt tgaccgcttc
    52321 acccattaat tctgaacatg taacgattgt taagttttct ggatgacgat tttcttctgt
    52381 gaaaacagaa tcagtgatac aaatatcttt gattggtgca ttgtctaaaa tacttttcgc
    52441 atgatcggac aataatccat gtgacgcaca ggcatatact tcttttgcgc cgttttcttt
    52501 taatacattt gctgctcgtg caagcgttgc tcctgtgttc aagatatcat ctaccatgat
    52561 acatgtcttt ccttgaacat caccgatcac ataaccaccc tcagttgaag catcatctgc
    52621 atgatctacg atggctaatg tgctgttcaa atattctgaa agactacgtg cacgctgaac
    52681 accgctgttt tttggcgaaa caactacgat gtcatctccc gtcagaccta attgacggta
    52741 ataatgagca aacaacggca tcgtaaataa attatctaca ggaatatcaa agaatccttg
    52801 tacttgaacc gtgtgcagat ctaaagtcag tactcgagtt gcccctgctt cttcgatcaa
    52861 gttagcgatc aatttcgcag tgatcggttc atgaggtttc gccgtgcggt cttgcctagc
    52921 atacccatag taaggcaata cgacattgat cgttttcgca cttgctcgct tcattgcatc
    52981 gatcatgatc agtagttcca tatagtaatc attgacaggt gcattcgttg attgaacgat
    53041 atacacatga tcccctcgaa tactttcttc gatattgatg gaaatctcgc catcactaaa
    53101 ttgcttcacg acgcttttac ctaattctgt tccgaacact ttcgcgattt tttcagctaa
    53161 tggacggttg ccattcaaac taaaaatctt caacgtgtca tcctgatact tattactcat
    53221 gtagtcctcc ccaaaacttc tctattcttc gatagtttaa catatttttc caagattttc
    53281 tgttaatttc agcaaattct taaggaagtg aaactgttcc gttactccaa ctggcaggaa
    53341 tgactttatg ataatcgccc cagttgtcgt gtactttgta ataacgttct cctgtttcag
    53401 tttcaaaata agcgtacgct gtcacccaat gattgccata tgtactgcca agtactttca
    53461 aaataccaat catcacaggt ttgccttcac gtatacgttt tgtagctcgc tgccatgaac
    53521 ctagaagagt tgctcgtgca cgctcatgat tgccattctt ctttaaaaaa ctagaaatcc
    53581 ctgtactaac ctgaaaagga atcgtaggaa gtcctagtgg ttggatctgg ctacgcaatg
    53641 ccttcgtcaa aaccaacgaa tcagccgtat ttttcttgcg aatctcattt ggaagcatcc
    53701 accccttacg atagtcttga taataggcaa ggagaactgc tgccgcgtaa gtaccacaaa
    53761 gatagcctga gggggtagcc catttcttat acctcaaaaa acgttcttct ggcaatccca
    53821 cccagcaatt tgcgagttcc tttcctgacc ttttttcttc gatcaaaacg ggaatatctt
    53881 cttttctgtt gatccatcta gataactcga ttggctcttc attgatcagc ttccattttt
    53941 tacaagaaag accctcttga taagtatatt ttgctggaga atattctacc ggatgtcctg
    54001 attgatcgat aatcacataa ctttgatctt caaaaaccag agctaaaaaa agcaatttac
    54061 tttttcttga ctgcagctgc tgagtgctgg ctaatttttt aattttttta tctactttga
    54121 aatataaagg tttatccact acttgattca gttgggatcg cctccttttt ttcattataa
    54181 gtgaaggatt gaaaaaaaca aatcagtttg attgttcgaa ttttcaattt tttatgttct
    54241 atttgttaat tccttcattt tgtaagataa tgggcacacg aaacaaaaaa ggagcgatcg
    54301 atgaatgaac aaagaacgat tgaaacaaga tttctatgaa gcagtcaatg aagaatggca
    54361 aaaaacagca aaaatccctg cagataaacc agctacaggc ggtttccaag atttagttga
    54421 cgggatcgac caacttttga tgggagaaac agacgatctg cttgcccatc cagaaaaagt
    54481 gtcttcagaa aaaatgaaac atttccttgc atattatcaa ctggcaaacg attatgaccg
    54541 aagaaatgag ttgcatgctc aaccgcttca acctataatc gaaaaagttg aatcattgca
    54601 gtctttcgac gaattgaata agcaatttcc agaatggctg ttggatacat taccattgcc
    54661 atttaatctg gatgtagatg cagatatgaa gaatgcgcaa acgaacgcct tctttgctta
    54721 tccgccttct ttattccttc cagataagac gtattatgca tcagaccatc ccaacggtgc
    54781 acaactaata ggcgttttct ttgatatggc tgttcagtta ttagagcttg ccggcaaaga
    54841 aaaaagtcag gcagaagcaa tcacggaaca agcagtgcaa tttgataaat tgattgctcc
    54901 tcatgtaaaa agtgcagaag aaaacgcaga ttacagcaaa atgtataatc cgcaatcttt
    54961 tgatacattt attaaataca cagataaact ggacttgaaa aaacttgtca cgggtttgat
    55021 tgggacaact ccagataaag tgatcgtaac tgatccagtg tacttcgatc atttgaatga
    55081 catcctgaca gaagctcatt ttccgttatt caaaagctgg atgatcatta aaacagtacg
    55141 ttctcttagt ggttatctat cagaagaatt ccgccaagtc agcggaatct attctcgcgt
    55201 attgtctgga acagacgaag caatgcctca gaaaaaagca gcgtattacc ttgcctctgg
    55261 acaattcgat caagtagttg gcgattacta cggaaaaaaa tattttggcg aagctgctaa
    55321 aaaagacgta gaacaaatgg tgaaaaaaat gatcgccgtt tataaaaaac gtctagaaga
    55381 aaatgactgg cttggggatg caacaaaaga aaaagccgtc ataaaattaa ataacttagg
    55441 tatccaagta ggctaccccg ataagatccc agcattattc gaccagttca aaacagtacc
    55501 tgcagatcag ggtggtactt tgctttcaaa tactcttgtt ttcagcaaac tcacattaaa
    55561 agatcgtttc agcaaatgga acaaaccagt ggatcgttca gaatgggaaa tgagtgctga
    55621 cacggtcaat gcttattatc atccatttcg gaatgtgatc gtctttccgg cagcgatcct
    55681 tcaagcacca ttttacagtc tagaacaatc aagctctgct aattatggtg gaatcggagc
    55741 tgttatcgct catgagattt cccatgcatt tgataataac ggcgctttat ttgacgaata
    55801 tggcaacttg aacaactggt ggacagaaga agatcttaca caatttcaaa acaaagcaca
    55861 agcaatgatc gaagaattcg atggtctgcc ttttgctgac ggaaaagtaa acggaaaatt
    55921 aaccgtttcg gaaaatattg ctgatgcagg cggtctaagc tgtgcattgg aagcagcaaa
    55981 aacggaatca gatctttcta tcgaggaatt ctttgtcaat tgggcaacga tttggcgtac
    56041 aaaagcaaaa aaagaatacc aacaactttt actgcaaatc gatgtccatg cccctgctaa
    56101 actccgagca aacgtgcaac caaaaaacct tgacgaattc tatgaaacat ttggtatcac
    56161 ggaacaagac gctatgtatc tagcgccaga aaaaagagtg cgaatctggt aagaggttgt
    56221 gccagaagtg gtcagcttca agaaataaga aggaatttgg gaaaatcgct tctcaaattt
    56281 ttgtgacatt tcggcttatt tttcgaagaa gttacttctg gaataccatg tattagaggt
    56341 tgtgaaaaag ctgcttagtt tcaagtagta agaaaaattt tgtgaaaatg gctttccaca
    56401 tttttgcata aatttgactt actaccgaga aactggcttt tgaacaccgt ttatcgagag
    56461 gttgtgaaat cagcgtcctg acctgagtat tagagaaaaa aacggaaaaa tagttcctca
    56521 tattttgccg tttgttgagc taataccgag ggtcagctga ttgaacaccg tttagtggag
    56581 agattgtgaa aaagctgtcc tgcatcaagt aataagaaca gccaatcaaa agcagcaagg
    56641 agaacctcat ctataaaaag atagaaggaa gtgagacatc tattggtctc atttccttct
    56701 atttttactt tcctcagtca attgttttac atcataaaag gagaaattcc acttattttt
    56761 ttcgctgttt catgacataa acaactacac cgattaacaa aattcctcca gctaatgcta
    56821 gcaacgggtt attaaattct cccgtttttg ggagtccttg agtgccattt ttttcacttt
    56881 cttttgctgt cctatccgga tgagaaggtt ttccatttgg ttttccattt ggtgattcat
    56941 ttcctggatt ttctctttct ggtttgtcat ttcccggggg cacatcggca gtttctcgca
    57001 cagtgatcgc tttttgctgg gtaacagatt ctgtatgagc agaccatttt tccccatcaa
    57061 atatttccga acgataagtg acttctagcg tatattctcc ttttgaaggt gctgaaaaaa
    57121 tagcggtatg attagaaaat tgagcacttg actgtgtttc aacgatttgg atcttttctg
    57181 ggaaataacg catatcttca aagacaggcg ttccttgatt tggtgtgaaa gttgacacaa
    57241 aaactgtaaa aggcttcagt tcaatgatat ttccttctgc attctccgcc acaccatttg
    57301 cttcttgtat aataatcgga ttattttgtt catttggttt tgtctgattt ggttcttgta
    57361 cgattgcata ctctggatat tccgaagacg gtgaggtttc tccgtcaaaa atagcaccta
    57421 cagataatgg aagaccatcc actctttcct tttctgtttg acgattcccc ggtttaatct
    57481 gcatcagtcc atgaacatgg atacttccat tttcatagcg cgtaacaggc tgctgacctt
    57541 ctttcgaaca tgtatttaga gactcgatcc aatcttttga tatggtatgt ccaagagtat
    57601 tttctgattg tttctctcgt tcattccaat agtagttcaa cgagtggtag atttgatctt
    57661 cgttttgatt caatgggcgg atctgctctc tcatctcaag attctctgtt cggaaagata
    57721 agataccaga agcatggtag tctgtgtttc ctgctgaaga ggtataaaga gccacattat
    57781 atgaaccgtt attaaaactt gtactgctat tgacgataat atctgttccg ctattggaat
    57841 cgattccttt cgcaagattt tcgaaagaca aactattgat caattcatga gggcccgtta
    57901 aagaagaacc gcccattttg aatccattac cgttaccttc tccctcaatt cctggtaccc
    57961 agccgtttcg ataagcaact gagtttttga tgattacttt tccgatcgaa cctgtttcat
    58021 ttttagcaaa aaggtcccaa ccgtcatctg cattatgata cgcgatacaa ccgtcaaata
    58081 catttccttc tcctattgtc agtttggccg caaatccatc ggcatcttca aatcctggat
    58141 cggcattttc aaaagatgta cagttcttga ctaagttatg cgcgggccat gcttcgaaag
    58201 gatcatttga gctaccgctg atttggattc ctgtatttcc attccgataa gcatgaatct
    58261 cttcgatcaa attatgattt ccagaaatct gtaatccttt ttgcatagct gcactatttg
    58321 taatgtcaaa ccctcgtaaa ccccagtagt gactgaacag tgtcatccca tttccagttc
    58381 ctttaaaatc aagtacagga cgcttgtttt ctggattttt ctctgcaatc aactgaatcg
    58441 ggttttctct tgtcccgtta acgccttttg gaatcgtcaa tcctctttcg aaggaataag
    58501 ttccaggcgc catgacgatt gtctgcccag catatgcgta tctcaatgct tgtgtcagag
    58561 ataatggatt ttgtctgctt ccgtttcctg catctgaccc ttctggtgtt acataaactg
    58621 tcgaatattt aggtttacgg tagtccactg tatgaagaat ctcttttgtt tcataactag
    58681 tcatctctac gtattcttct ggcggatagt ttttatctgg cgtaaaactg aaagtaaatt
    58741 cgttcgttcc ttccatcagt tttgtctgat aatcaaattc ccgattcgca gtgatagcca
    58801 agttttttgc gttcttaagc acctctcctg ttgctttatt tttaattgtc aataatccgt
    58861 cagcatttgc tctaaaggac atagtatgat cttggtttcc tgaatgatta ctagaggtca
    58921 cagtgtaaat cggatcaatc aagcgagtag gtctttcttg cccaggagga tctgtcgcag
    58981 gatctgagta agcaacttcg attccttcta ccttgatcgt catattcctt gctgcagcaa
    59041 atcctgcata aataaccgat tcatctgaag cgtataattt ttcccagtca tacatgatgt
    59101 cagaagccat ttcttctcct gtttcaggat cgtaataata tgcctctaaa ccagtattcg
    59161 tttttttcat ctctacgtcc agtttagtaa tcgagttcgt ggccggaaac agattcccat
    59221 gaccgtttcc gaatatatta taagaacctg tttctttttc caagaaccct gctgaagtct
    59281 ctaaaggtgt tgtttccact gagacactcc caggagctgg cgcagcttgc ggatcttcag
    59341 atgatattcc tgtgattgcc cgtgtcccca atccaagtcg catcgtatat ttgctgccgc
    59401 tcgtgttgac cacttcttgt ctatccgagt cccagacata ttcgatccga ctgcctagta
    59461 tggcaaatga atttgaataa aatgcctgcc caaacaaatg attttttggt actgcgtctc
    59521 ttaccattaa agcaaatcct tcttgggcat tcgtataggt ccaagattct atttcgatcg
    59581 tcgcccgcat cctaaagttg atgtctttgg ggattgcttg ataataatag gtcattccat
    59641 ctgatccgct tgactggaat tttccgccgt tattcgtgga agagagccgc acgccgtctt
    59701 ctaatggttc aatggcatac ctactagcac ttgtgctttc tccgaaaaca acccctttcc
    59761 actcttcatt tgcttcttca gattgctttt ttgtcttttc attttctgat tctttcatca
    59821 taggatcatt tccttcttcc gtatccatat cttcactagt tcttggtatt tcctccattg
    59881 ttgacatccc ttcaatgttc acgtgtgcat tttcttcgtt cacagactgt tgttcgttag
    59941 cagcaacttc aacgacagaa attaaaaccg gggtactgag cataaggaga ttcatcatta
    60001 gcgcactgta ttttatacgt ttttttaaca agtgtattcc tcccgtaaca aattagaaag
    60061 cgtttactta aagtattacc taatttattt ttactgtcaa taaaaaacaa aattataata
    60121 agtgtatttt ataaaaagaa aaaatataac ttaagttgtt gataataaag agatttatta
    60181 acgtaaaaag aataagtttt tttaaaataa cgtataaaaa agagcataaa acaaagtcgt
    60241 ttgttttatg ctcttctttt attattttgt gctttttatt ttatcaaatc actttgtttt
    60301 tttataaaat ttctgcgcct agtgtggact caaaatgtct caatgcccat tcatgtccaa
    60361 cgggatcgaa acttgccacg gaatctttga aaatatggag tttgtatcct agattatacg
    60421 catcgactgc tgtatgcaac acacagatat ctgtacatac gccggtcaaa taaatatctg
    60481 tgatctggcg ttctcgcaaa cggatgtcta gatctgttcc actaaaagcg gaataatgcc
    60541 gtttgtctat ccaataaaca ttttcctctt gctcatagtc ttggtataaa ctttttaaag
    60601 agccgtacaa ttcccgtcca cccgttccta tcacattatg cggaggaaat aagcggttct
    60661 ccggatgaaa ggaatctttt ggatcatgcg catcaatggc aaaaacgaca aaatcctttt
    60721 gatcaataaa cttctttgta tgagcagtca gctttttttc aattacttgt cctgctgtcc
    60781 cagtagtcag ctttccatcc tctgcaacaa aatcatatgt gtagtcaatc gagatcaatg
    60841 cgttcatctt agtcctcctt atacgagatg tttgacaaat tcgatcacca tttctgctga
    60901 tcgtttgcct gcgtcttcga taaattcgtc aaagctttgt gtcgccgagt gatctgctgt
    60961 gtcgctcatt gcacgtacga tcaaaaatgg gatattgaac tgacgagctg tttgtccaac
    61021 agcggctcct tccatttcgc aagctaatgc ttcagggaaa ttcgttaaga tttctttgat
    61081 tttatctggc gagtcgacaa atgtatcacc tgtaacgatc aatccttctt ttgcgttcaa
    61141 attcgttgct tttgctgctt taaccatttc actgcgcaaa tatgtgcttg cttcataata
    61201 tagaggcatt cctggtaatt gtcctgggtt gtagccaaat cctgttgcat ctgcatcaaa
    61261 ataagctact ttgtctgata taacgatgtc acctacttgt aagccttcac cgattccgcc
    61321 agctgaacct gtattgatca ccatgttcac gccgtattgt tggatcaaca gacttgtggt
    61381 aatagatgct aagacttttc ctataccgga acgtacgacg atcacttcgt ggttacctaa
    61441 tgaacctgaa ataaataaag cgcctgcgcg ttcccatgat aatggttcgc ttaggttctc
    61501 tctcaaaatt tttacttctt cttccattgc gccgataata ccgattttca tctttttaat
    61561 tccttctttc tatataaatg cgattgctaa aaaaaccaca cataacatta ggataacaat
    61621 aataagagat ttcatcaaaa aagagttcca tttggtcgtc ttttcccgtt cgctgatcct
    61681 tgttttcgtg attggtttat tctttttgct ttctttacga taaaagctgg caatcttttt
    61741 ttcttcttgc tgataagctg tttctgcttt tcgctgtttt tttaatgact cgcttgcttg
    61801 tgcttgttgt cgcttgcgaa gttcgcttcg cgtaataagc ggtcctttgg ccataagccg
    61861 atccctctac tttcctttgg tcaatagttc ccagtattga atcgcataaa tcgtctttgc
    61921 atcacaaatc aactgatctt tcatcgcttg ttgcgcctct tcaagagtta gatgatacaa
    61981 ctccagtact tcgtcttcat cttgtgctaa aggattctcg accttctcta ccccttgtgc
    62041 atgataaata tgaaggactt catttgcaaa acctggtgaa agatacatcg aagtaagatg
    62101 gctcagcgac ttcgcacgat agccagtttc ttcttctaat tctctagctg ctgtcatttc
    62161 gggattttgt ccttctcctg gatcgatttt tccagctgga atctccaaaa tcactttttc
    62221 taaaggtttt cgaaattgtt tgacaagaag cagacgatct tgttcgtcaa aagcaatgat
    62281 cccgacaccg ccaggatgaa ataccagttc tctcttcgaa gttcctccat ctggcaaacg
    62341 aacttcgtct acagcaacat caataatttt ccgctataga tttctttgcg actgattgtt
    62401 ttttcttcaa attgctcatt gttcagcata tcttctcctg ctttctttgt aatcataact
    62461 gctttttttt catttttcaa tttttctcaa aaactcctta ttagtttacc atagataaac
    62521 cttagatttt ctctaaatat agaaaatcct tctttagtcc gatactcttt ctagtagtcc
    62581 gtatgctaaa ataagtatgt aatcgaataa cgaaaagaat tcaatactca acgataaatg
    62641 acatggaggg tttattatga taaaacgaaa ttggccgtgg cttctagcat tggtcttgct
    62701 atttctcttt gtccgaaaca atagtttttc ttttgttcta ggacttttat tgataggtgt
    62761 agttttagtt ttgtggggac tctttggttc gcgcaggaaa aagggaaaac aagaagaaat
    62821 tcctgcactg actgacgaac ttgaaactca ctatgaaaaa agcggtatga cagcgaatga
    62881 aatttcattt tttcgacaaa caatgaatca aacaaaaaat gagatcaatc aattgcaaat
    62941 gaatatgcag cagacagcca aacttaaagc aatcgatctc cgccatgatc cagtcaaagc
    63001 agcgaaagct ttattcaaag aattggtgaa agaaccaaac cgactgcatg aagcaagtca
    63061 gtttctttat acgcatctgc cgaatctagt tgatttgaca aataagtata atgagatcaa
    63121 tgaccatgag atcaaaaaca aacagaccta tgaaaaacta gaagaaagcg cgcagatcat
    63181 cgaccagctg tcagctttaa tcgcacaaga ttatcaaaaa ttcgttgctg aggatctaga
    63241 tgatatcgac gtagagatat ctgttgcgaa acagagctta aagcgtgata ataaatatga
    63301 accagaacaa aaggattaac tcttttgttc ataaaagaag actcggaaca ttcagatgat
    63361 gtctggctgt ttcgagtact ttttctaaag tagagacatt catgtaagaa tcgagaacag
    63421 attcaacaag gaggaatttt ttatggatca taaaccgact gaaacaaaag atgttacacc
    63481 agttaacgat acacttgaag atttattgaa caacccgttt tcaactccaa cagatacgct
    63541 gaccacttca caacaagcgg agattgatca gctccaagag caacagacag ctgctcgttt
    63601 aattgacaaa ctaccggcgg aacgccaaga acaagctaaa cagctagcag caaaaatcga
    63661 tgctaatgat gcacagtctg tcatcagcta cggatcggct gcccaagcaa aattaagtga
    63721 attctcacaa tcgatgttga atcatgtgca agcacaagat attggtcctg taggagattc
    63781 cttaactgaa ctgatgtatc gtctccaaga agccaatcct gacgaactgc gtgccggaga
    63841 agggaacatc ttccagcgtg tcttcgggaa ggtcaaacaa tcgatctatg aagtgacagc
    63901 aaaatatcaa aagattggtg cacaaattga caagatttca gtgaaattag ataaagaaaa
    63961 agacggtctg ctaaaagata atctgatgtt agaacagctt taccagaaaa acaaagacta
    64021 ctttgatgca ctgaatattt atatcgctgc tggagaattg aaaatggaag aacttcaaac
    64081 aacgatcatt ccagaagcga tgaaaagagc agaagaaact ggcgatcaga tggatgttca
    64141 gattgccaat gattacacgc aattcctaga tcgtctggat aaacgtacgc atgatcttcg
    64201 cttagctaga cagatcacga tccagcaagc accacaaatc cgtttgatcc aaaacacaaa
    64261 tcaggccttg gctgaaaaga tccaagcatc tatcgctaca gccattccgc tgtggaaaaa
    64321 ccaagtcgtg atcgcattga ccttgcttcg tcaaaaagat gcagtaactg ctcaacgcca
    64381 agtctctgaa acaacaaacg acttattgaa gaaaaattca gaaatgctga aaatctcagc
    64441 catcgaaaca gcgaaagaaa atgaacgtgg aatcgtggat atcgagaccc ttcaaaccac
    64501 tcaaaatgat ttgatcgaaa caatccaaga gacattgcgt atccaaaaag aaggaaaaga
    64561 aaaacgtcgt catgcagaag tagagcttgg acacatggaa gaagatctga aacaaaaact
    64621 gttggattta acccaataga tcacctttcg cttgttacta aaacaaacgc ccaacaacag
    64681 tttattacaa ctgttgatgg gcgtttttct tatctttctt ctaacttctc cattggagtc
    64741 tatttctcat tcatcttgct gtgtccatag ccatagccaa aataaatgat cagtccaata
    64801 accattacga taccgaacac gatccatgtc acagtttgca gacgaagcat caatacaata
    64861 caagtcaaaa tggagacgat tggcaatagc ggaacgaatg gcactttgaa ttctccagct
    64921 tttggtttgc caaacatttt tctcaacttc agtaagccta gactaacaag catcaaatag
    64981 gcgagcgcca tgatattcgt tagttccgct aatacattca atgggaaaaa tccggcaaag
    65041 aatacagctg ccacaccagc ggcataagtc gcttttttcg gtgtacgatg cttttgatcg
    65101 atttctgtca taaacttagg aagtaagcca tccttgctga cagcaaacag taaacgagca
    65161 agtgaataca tcatcgagat cgttaccgtc agtagcgtta aaattgcccc tacagcgatc
    65221 accgcgccca ctgttccatg tcctacatac ctcattgcaa aagccactgg gtcattgact
    65281 cctagttcag tatacggaac gattcctgtc aagatcagcg tcacgatgat gtaaaggaca
    65341 gtagcaatca gtatcgaacc aatgattcct cttggcacat ctttttgcgg gtttttgact
    65401 tcctcggctg ccattgcaac ggcatcaaat cccaagaaag caaaaaacac aagagctgca
    65461 ccatctagca caccggaaaa accaaaaggc atgaatggct gccagttatc aggtttaacg
    65521 aaaaatattc ctacaatgat aaacaacgcg atgataccaa atttgacata taccatggca
    65581 ttattcaaac gtaatgcttt cttggcttca agcgacacga tgtaagtgac gaatatcact
    65641 acgagcaccg caatcaagtc aatgtatgta ccattttccg gattgtaccc gccagttaat
    65701 gcttgtggaa gttcggcccc taaacttttc aaaaaacctt gcatatagcc agaccatccg
    65761 gaagcaacag aggaaaccgc tagtaaaaat tccccgatca acaaccaccc tgtcagccag
    65821 gcagcaaatt caccaaatac aacatacaga taggcatatg gcccaccaat cactggcact
    65881 cgcgaagcaa attctgcgaa acttagtcca gacaaaatga caacgattgc agctaagaca
    65941 aatgaaagtg acagtgctgg accagcattt tgattggccg caacccctgt caccacaaat
    66001 attcccgtac cgatgatcgc accaattcca agcatgatca aatcagacgt ttttagttct
    66061 tttttcatct cactcgtatg attgagattg atctctttct tacgaaacaa atccattgaa
    66121 gttcctcccc attttaggtt ggaaaacagc gattaaactg ttttcatata ccctaaaagg
    66181 ataccaccta aaatgactaa aaggcaacca acaataacat aaatgagctc ttttttcgtt
    66241 tttctttcgc caaggatgaa aatcccacct aaagtagaga taatgatccc catttgtgaa
    66301 agtgagaagc caacagctaa accaagtgat ttgactgtta gaagcatgca gatgtttcct
    66361 aagccccata ataatccaca gatcatgttt ttccacacaa actgatcgac tttaacttta
    66421 cggaaagcaa agaagcttgc gcctaagatc attccgatac tttgaggtaa gataattgac
    66481 atcgcatcca aattcgccca gttgacgatg atggtatata caccataacc aatcgtagag
    66541 aagatcaatg ctctaaaacc cttaccaaaa tcaagcattt tattatctgt atctattttt
    66601 ccttcgtcat cttgtcgggc agtcaaatac gcaccgctta caagaagagc taaagcaata
    66661 ataccgtata cataatcttt cgtttgtgtc cattcatgga agaaaacggc tcccgcaatc
    66721 gtattcaaaa ttaattgaaa accagtagac aatggtagcc ctacagaaac acccatgtac
    66781 ttcattccat ggaactgtcc attttgtcca acactccaag ctaagccgga taaaaatccg
    66841 atcaagaaaa tccaaggggt gattacagga ctaacaacga aaaagacaac taaagaaaac
    66901 agaaatgcac cgatcgtcat tcctagtgtt tgttgattgg catcgccacc aattttacca
    66961 cttactaaac caatactacc ccatgccaac atagggacta atgctattaa aatttccata
    67021 accaatctcc ttttatttca catgataaga aacttatcag cgaaaacgtt aacaacacaa
    67081 gcactttttt tcgtttctaa cgattttcta acgtttttca ttataaaaat ttaagattgg
    67141 gaaaaataaa gtcattgttg tcccttttcc ttcagttgat tcagccgtca aatggatacc
    67201 taatttttcg gccagatttt ttgctaaata aagtcctaat cctgttgaat gtgttttgct
    67261 aagtcgacca tttctcccag taaatccctt atcaaagatc cgtttcaagt cttccgctgg
    67321 gataccgatc cctgaatctt taactgaaag gctgactcct tgcgcttcct tttctatgct
    67381 cacaatgatg tttccgtgat ccggcgtata tttgatggca ttactaagca attggttgaa
    67441 gataaaagcg atccatttag catcggtcaa aacagtatga tcctcaccaa cgatctcgta
    67501 gcgaatattt ttttggataa aataatttgc ctgactgcgt atcacaggct gaatgattcc
    67561 ttttagtcca tattcttgga tgaggtagtc ccgcgagaaa ctgtcgagtc ttgcataata
    67621 caaaacttgt tctacgtatt catcgatttt tgataattca ttttctagta atgtatactt
    67681 ttgatcgtca atatcgaact cgatcgaacg aactagcaat ttagaagcgg aaagtggcac
    67741 tttgatttca tggacccatg agtcaatata atctttttgg tcttgttgat tactgattgc
    67801 tgattgcatt acttcttggt gttcacggat cagctgattg atatattctt ctaccagttt
    67861 ttcttcttct gtcctcccac cactcaaata attttgcaaa ggggaagttt tttgtatgtc
    67921 ggctaatttt ccccaccatc ttctcttgct caagtaacca cccagcagat aaaaaatcag
    67981 aaagacgccc tcaatcaaag ctaaataagc aattgtgctc aaatcaactt tgatgtttgg
    68041 cgccagccac atcacaaaga tcgtcaatgc aataaaaaac agccatccca agatcaatgt
    68101 ccactgatct ttcaaatatt taaaaaaatt catcttaacc gctcatcctt tcagggaacg
    68161 atatatccct gtcctacttt tgtttcgata tatccttgga tacctgcctg ttcgattttt
    68221 cggcgtaacc gattgatgtt gactgtcaat gtattgtcat ctacaaatcg ttcgtcatcc
    68281 cacagtgctc gcagcaattt ttcccgactt aagatctttc cattgtgctt catcaaaata
    68341 aataatagac gatattcatt tttgctcaaa tcaatgatct ctccgttgat ttccatactt
    68401 ccgttgtcaa cattcaacgt aatgccattg tggctcatca tttcactaga taattctgtg
    68461 tagttgtaag aacggcgaag taatgcattg atttttgcaa tcagtacatc gatttggaaa
    68521 tgttttgtca caaaatcatc tgcccccatg ttcatagcca tgatcatatc catattcgta
    68581 ttcctgctgg agataaaaat gatcggtact ttcgatactt cacgtatttt ttgacaccaa
    68641 taatagccat ccaaaacggg aagattaata tctagtaata caagctgtgg ttcttctctt
    68701 tcaaagtctg agaacacttg attgaaatcg gtcgttccaa aggtttcaaa ttgccatttc
    68761 tcaagttcct ccatgatcaa ttgtcgaatg atctcttcgt cttcgactac catgattttt
    68821 gccataaaaa atccctccat ctttcttctt gctactacaa tatcaaagaa gcccttgtga
    68881 aacaagttgg cttacctgga aaatgtcatt ttagcaaacg ttaaaaaaaa ctggaaatat
    68941 gcgatttaat cgcgtttgtc tcttccaagc agcttaaatt tattatgtta ttcttaataa
    69001 ttggtctatt atctgttatt tttctttcgt tgtttttgtc ttttaaattt tcgataacac
    69061 caataaccga aaagcgttag cactagcaat atacctagaa ggagtataag taatcgataa
    69121 agatggtatt tttttgtctg ttctatcttt gaagagactt cttctgtaaa gggaactcgt
    69181 cttcctgtca ctagtaatcg gtgagtgttc acggtgtaag gtgtacaagt gataagtgtg
    69241 actagatcct gcttttctct aattgctaat gtatttgttt ttgttggaag gacaacaatt
    69301 ttctcaacga cttcataagc gagcatccga ccatacactt caagatagaa tcggtcatct
    69361 tgctccattt cttcaagatc cgtaaagagt tttttctcag caataccgct atgggcggta
    69421 atcacggaat gtgtactctc tcctccagtt ggaaaagagg tgccttgcag gactgtcgct
    69481 cctctatcta acaaaagatc attcgtttca tcaaataaag gcaagctaac attgattttc
    69541 ggaatataga tggctccgat catatgttgt tcgtaatatt cttttcctgg attttggaca
    69601 tttctaaccg cttgctcaaa aggatctttg acttgtccca ttcctgggat tactgatgta
    69661 tgagcaagcg tctgattttt cttttcatgc actgctaatt gttgctcatg tttttcttct
    69721 ttatcgcgtt caagctgctt ttgataattc tcgatccttc tttgatccaa ataattgctg
    69781 agagcatctg ctaaaaatgg atatgtaaaa actgcagctc cggcaagaaa catcactgcc
    69841 ataaataatt gtaataaaag actgatttgg gtttgaggtc tattacctat tttctttttc
    69901 attttcttca ccttcttatt taaaaaaact gcagcaacct ttataaaacc gattgctgca
    69961 gcttattttt gttgcttata cttcagactt cattttagat ttacggtacc agctgtacgc
    70021 tccaatcatc aaacttattc cgattagtaa gaatgccaag agcccgttcc caccagtagc
    70081 aggaagtgac ccgcgtttca tattcggtac tctttctggc cctggatttt ctactcctac
    70141 gatctgaatt tcttcattat agcttccata agagatgata aattcagtaa aggctgcctc
    70201 acctgttgga agtacataac cttctggcgc catggtctct ttcatttgat aggttccata
    70261 atctaaccct tgaacctcaa agtatccatt tccatctgcg acaaattctg ttgcttgtcc
    70321 gcttgttgcc cactcaattc tatctgctcc tgattcataa acagctaaag gcgactcccc
    70381 tttataaaat attgcgtatt cagaacggtc ttcattccac aattcgaatc ttgcatcttt
    70441 aagcaattca ctgcttgatg catcatattt ttcaaacttt cttccacctg ttgtgacttt
    70501 ctctggcggc tctactcctt cttcataatc aaattcatca tttcgtccga tttcaataac
    70561 cgctgtgttg ttatggaaat catccgcttc tagttctgtg gaaaccttca aattatacgt
    70621 gatcgttaaa tctcctccac gtgcatctgc taatctacct aaagtatcta ctttggctac
    70681 tccattttct tctgtcaaaa tcgtcacgac aaacccgttg cttactactt ctactatata
    70741 atcttgtcct tttgttaaaa tcgtctcgcc ggctcgcact tctatttcct gatcataata
    70801 agttagacca actgtaggcg tatctgtgat tttgtaattt ttgataacag cgcttccgtt
    70861 ttcaaggaca gaatcgatga aataaggaat aggtgctgtg atcgtgtaag aagccgtttt
    70921 tcctctttct agatcaatat aagaaatcgt ttcttgttct ccagcttcat taataatcgt
    70981 tacttgtcta aggtcgcttt cctctacatt catctgttta tctgcttctc tgatttcgtt
    71041 tttcggatac aaatgcacat ctgtattgta tgtgtctttc catgtagaac catcccacac
    71101 gccatccacc atatcaggca tcatcactgg catcataaca accattggag acgcgattct
    71161 ggaaatatga gctggcgaat aagtttctaa gaaaagatag actttatctc tagaagaagg
    71221 tgcttcttcc gtcacttgga cggtagagaa taccgcttct ccagcttcat tcgttgtttg
    71281 tttgtcaata cttgtcagtc gatattttaa aaaccaactt tctgtgtgcc gtttttgaat
    71341 ccattcaatc gcttcggcag aattaagacc gtcttctcgt tccggtgtta aaggattatc
    71401 tcgaatcaaa tcgtaatata cttccgttac gtcaaacaaa tcaaaatcga ctcctggaat
    71461 attttcttca ccaaaatccg tagaaaccaa tccgctattc ggtcgttctt ccggaacaga
    71521 tgagaaacct tttttgtgta atgtaatcgt cacttcactt ggtttttgtg cgacttcttc
    71581 ggctttgact agttttccgt tcccgaaaat ccctattccc gcagtaacga gtaacagtac
    71641 actcattccc gtgacaatca tttttttatt catttttttc tccccgttct ttttttatta
    71701 ataaaacagc acctaacaat aaaagaattc ctagtaaaga aatcaacgtt cttgcttcat
    71761 tcgtttgcgg gaatacggac cattttcctg attgacctgg attgcttgga ccactcggct
    71821 ctttcggttt gtccgttgtt tcttttacgg tctcgttata aacacgtggt gttgcggatt
    71881 cataggcaga gactggaact ttcccggatt ctaattcagc catctcctgt ccgttaacta
    71941 ctacatattg tggttggcct tttgcatcca cccaaaattc agggatgatg acctcgattc
    72001 tcttacttgc ttcatccatc tcgtaacctt ccacaccttt taattcttca aaataatagg
    72061 tgccagaagg caagaaacgt tgtcctgtcg taacaaggcc ctctttatcc gaaatgaatt
    72121 tgcttacatt tttgtcattc aaaggatcat tgtctgctgg tttgatccat tgatttttca
    72181 agtcattagc aggagccata tctaaataat atttcccccc ttctatcatc tgatatagag
    72241 caaaaacagc accttctaat ggttttcctt tttcagttgt tcctctttga cgtccatact
    72301 tgaagaagta tggatctctt agataaccga catttttagg atagatatga atctcttgca
    72361 gttcctcggt tgattctgtc gggtgataaa ttggcaaaat agcagcaatt gggatagctg
    72421 tctgatcgat atcaacatcc aatccaactt ctggatcaat cgattcttcg aaaatcaaat
    72481 aaactgcatc ccgatcttgg tttttcttag gtgctttgat acgtgcaatc ccgtctccta
    72541 atccgccaac cgtatctttc ccagttgtta ccgaagtccc tatttggaca agcctttctt
    72601 ctgtgattag ctgacggata ttgtttctgt tcgtttcagc gatttgctgg acgaattctt
    72661 taggagtcat gttttcagca gctttttttt catgataata atcggtcatg tcgtaaatgg
    72721 caaatgtcgc tccatttagt ggcaccgtct gtgaaatgat atctgctgtt tcccctgctt
    72781 cctcagagat agccaagcca tcattttcat ggtattcaaa ttgatcgtta taatcgatat
    72841 ctcgaatcat ccgtttatgc aacacgaatt ccacgacatc ttcccctgat tcttctgccg
    72901 acatcgcatg tggaagaagg actgctgcaa gcggtagtaa aacaagtaat tgaagcatca
    72961 aacacaacag ctttttcatt accttgctcc ctccttttta gattgtctga caaacaaacc
    73021 ataggctgct cctgcaagcg ccatgaagaa tgcagcaagc aggatataga ataatcgtcc
    73081 ggatcctcct gtagcaggca acggattttc aggatcgttc ccgacactaa gctgtaatct
    73141 gattcgattt gtctccaaaa gttcatattc taactcttgc tgtagatcag gcgtctctgc
    73201 ttcttcgttt ggataatacg aaatctcaac ttttagtgta cccgcttctt ttcctggaac
    73261 tacccgatca ttttctatgt caggttcttc tcgataacta atttctaaaa taaagtaacc
    73321 tggaagtttt ctatagctgt caggtgactt cacttccttg atccgataga ccccttccaa
    73381 caagtctgaa gcattgaata gggaagaatc gtttggatct ggtgccaagc ctccctcgat
    73441 gatttcatac tctcctgcac tattttgttt ctcaattgaa aattctgcgc cttcaagacg
    73501 tcggctattc atactgtcaa ttttcaaaag ttccaaatcg attggcgcta gttcatcttc
    73561 taaggttact tgtagtacac catcgatgat ttcatagcct tccggcaagg gagcagtttc
    73621 gtcttcgatg accgtatctt caatgataaa cttaccttct tcattcagtg caaactggaa
    73681 cacttgatca gatagccgat acccatttgg tgcgacagat tccgagacct catattcacc
    73741 aatagacaga tgcagaggtt ggtcgtaatt taaatcgaca tacttttcta ctcctacggc
    73801 acgagaatag aagtatccga tcccaggcaa acgtttcgat tcttctggtt ctaacggatt
    73861 accagtgtat gctcgataca gcgggaagga agaatccccc actttcctga tatcgaaacc
    73921 tgcaccatct aatgtatggc cttcatggtc taattttcta actcggatct cccgataatc
    73981 aaacgtattg taagcagtga atgctaccca taaacgatcc tcttcatctg ttgtatacgt
    74041 gagatattgc caattttctt cacctgtttg cttgagttgg atagtcccta tagcattatc
    74101 gtaaagtcgc aagatccatg tgtcattttc atcaggttct ttgaaacctt ctgggttctg
    74161 gctctcaatg attttgtatt ctgcatagtt ggtagtttct tcactatcct tataaacaaa
    74221 tgaatctggc tctccgattg gatgaataac tttctcacca tccacgatta catatttccc
    74281 gtcttcatct actgaataga acgtgagtct ccctttctct tcctctactt cgttcacacc
    74341 agaaagccct ttcgctactg gatatccgat ttccagtccg ttaccatctg tttcataaag
    74401 ttcaaactct gcgccattga ttggcatatt actgccttca attagtttat tgatattcat
    74461 gtggattggc ttgaattcat ttcgcatttc cagtttgaca tacaactcat catactctgt
    74521 gccttctatg ttaggctctt gtacaacaga aagcttgtga tattctcctt cataatagga
    74581 attcggatct ttaccttccg gtccgccgac tctcgaacca gatgtatatt catctacaag
    74641 ctcgtagtga cctaacatct catcttcgtt ggctgcatat tttttgattt ggaattgata
    74701 cgtctcatct actaactgat aacgtggtgg tccagcgatc tctctgatcc aaaatatgtc
    74761 gctgactgct ccagtttcat ctcctaaaat cggcatcttc gtttcaaaga tcgctattcc
    74821 gtccgtggta gttttacttg tttcgattgg ttcggcttcc ccactctctg gattttggtc
    74881 atataatgca aattcgactc cagccaacgg ctcgccattt tgacccttct tgctgacttg
    74941 gaaattacgg cctttatgtt cgtaacgaat ggaagaagat gggaaataca tccgtccagt
    75001 agtgatatca ttctcataat cctccaggtt ctgaatatag gccatattgt tcactgtgca
    75061 aaaatttccg tcttgagctc ccgcatcaag ttttacttgg tacttgatcc tgaccatttc
    75121 cccttcacct aaagaaatcg gagaaaattt ataagcttgg ttttcccgtc cgacatacgt
    75181 tgtcggagtc gccactactt ctggtggggc ttgtccatga cgttcttcat cccatatttc
    75241 tggctcttgg tacttcatgc cgttttctcc tggatctaga tggtaaaact gaatatctgc
    75301 cgatctgcca gctccaaatg gtgagacatt aaaaccagtt tcatcataaa gtgtggcttg
    75361 ctggatcgtt ctcttgaagg tagaagagat atcctccaag gctgtaacaa tgtcattctt
    75421 gttgttcgca ttgtaatatc gcggtgttac gccatcttct tctaaatcag caatattttt
    75481 caatacattt cgtccaatag catctagtcg ttgtctcccg ctaacgtttc catcgattcc
    75541 taaaccaatg gagaagatac ttggcgggtt ctcttgatac ttgtttttca gccaatgatg
    75601 ataagcaact gtgttgatcg cagatgactt ttcttgcgaa gtaggactgc cattcgtatt
    75661 gttattagaa gaaccatcac caacccagtg agtcgcttta ttatctcctt cttttacctc
    75721 tccataacga tagtgtacat ttacttcatc ttctggacgg ttaaagtcag atgcataggt
    75781 aactggatga gtaaaccctg cattagaagt attcccagaa aactcctcaa aatttctgaa
    75841 caaaacgtca ttatcttcag caatcttatc ttccatcaca gtccagttgc tccaagctcc
    75901 attagtgctc gtacgataac ttgactgaat cggtgcataa ctgaaggtcg gtgtcccatc
    75961 tcccacaacg attaggattt tttctggatt tctattttct ccgccattgt ctttatacaa
    76021 tgtttcatag ccatttttaa gccctagtgt aagcggagtt cctccgattg gtgtacgatt
    76081 taatgctgta ttctcacttc ccgtcaaacg attgatatca tttgtcaatg gaaagatgtc
    76141 cgaactgatt tgctcatggt tattgatagc tgtactatta tggtaaaaat tcaccatacc
    76201 gattcgaata tccagactcg ggtcagagag cagatcttta ctcatttcgt ttactgcctc
    76261 aatcaacgca gcatttttag tttgactatt ggtcccagcg gttaattcac tcatactcgc
    76321 tgacttatct agaacaaaaa cgatatcgat tggactgatt tcctttttct cgcccccgat
    76381 gacatctaga tagacattgt aaagggttgt tgcatcttca ggatgtagat cagatgctgt
    76441 gctgcttggc agaacaggtt ctacccattt tttgatgtac gccccgttat aatccaagta
    76501 actgttttca aaattccgtt catttcccca aagctgaacg gtttgagctg gaacgtttct
    76561 atcttcttcg cctgcagttg atccattatt agtagcatag tcgtaatttc gccagttcgc
    76621 tcccccgttt gtataatcac tatcatcgat caagttctct ccgtcatatg gcgagccttt
    76681 gtctccttga tagcgttcat tgctttgtgt ccaatttcct aacacttttg tatagtcatt
    76741 cgttgtaaac ttcgggtagc gatgctgttc gttttcaact tctccgctag gatagatata
    76801 ttcatagggg tcttgcgtag ctgttggccc aagacgctcc aaaataccgt tgaataactg
    76861 gcgttgaatg cgctggagtg cttgaccgct gggtacgatt ggttcgtcca gcttttccat
    76921 ctcattttct tcgctacgtt gaatttcagc ggaatcttct gtatcagttt cattttcttg
    76981 taattcttgg ttatctattc tttcatcaac caccacttga agaggtagtt acccttcgtt
    77041 cacatcgggg atcttttctg tttcaaaaat caatgtgccg gtttctgctt cttttgaata
    77101 aacttttccg acataccatt cttgaccatc gatcgtctcg acttttaggt cttctccatc
    77161 ttcatcatag gaggatagac ctgttccacg aacgtttttt acggtaccaa tcccggcggc
    77221 tgccgcatcg attgctaaac gtattctacc ttcattggca ctttcctttt tttcaaaagc
    77281 cagatgccat tcaagggttt cttctttttc aatatacttc ccttcaattt ttgcatagtc
    77341 ctcatctaag aatacctcat cctcctttgt ttctgttgac tcagcagcta catccagggt
    77401 cgtcatatga tagactgact ggaaatatgg tccaaatagc aaactgacag ttactaactg
    77461 caaaagcttc aattttaacc ctttcacatc cttatactcc tttcaaaaat atttgtcttc
    77521 tttcacaaca atcaacaaaa caatgcccat ctaattataa tttaatttaa ttttaatttt
    77581 aaatcaaatg atatcctttt tagttaaaaa acaccaatta tacaacattt attattaaaa
    77641 ttaaattata aaattttata acgttctcat ttaacaaaac ttaagttatt aagacaaatg
    77701 aataaacaac tacgctttcc tcgaaacaaa aaaataaagc acaaatgcgc atttacgcac
    77761 tcatgcttta ttcgtacaat taattcagat aacggcagcg cataggatgc caataacact
    77821 tcctaaaata gctcctccta aaatgtcagt aggataatgt aaaagtaaaa aaatcctcga
    77881 ataagcgatc aaacaagcaa ataaaaaggc taatattcct gcaactggac ttaattcgaa
    77941 caacgcagct actgataaaa aggctagcgc tgtatgtcct gaaggaaaag aagaagtctt
    78001 cggtttactt gtgtaaagga caagccgacg atttttttca taaggtcttt tccgtcttgt
    78061 cgtttttttg ataaaaagca aaccaacaaa aaaatagatc aaactgccga taagaatggc
    78121 tagaccatat tctctagtat caggtatcaa gactaaaaca gcagcaagga gcaaccaaat
    78181 aaaaccacca ttagagatat tactgataaa tttcaaaaaa ttgatttttc gactatccgt
    78241 tttccgttgc ttggcgaact tgttgataat actatcatcg attttagcaa tcaaacgcaa
    78301 catgttattc ctccttttta agaacctttt cttgcgtacg atggataaaa agcaggactt
    78361 gaaaataaaa caagaaactg aaacctaata aagcaaaata gattggtcct gcaaaccaga
    78421 atgcgacaag aaggatcaac gtgcctgcca aatagaaaag cgcgcttttg aaatcattaa
    78481 aaaacaagaa aaatgcagta atccaagaag cttctttttg ttccagttga agcaagattt
    78541 tgtaactaaa gagaagcgcg cttaatagaa gcaaaaacaa cgtagtatac atcaatgtat
    78601 agccaattcc cccaccccaa tagcggaaaa tctgataatc gatcaataga agaagaaaat
    78661 aaacacttgc taaactatct tgctttccat aaagagagaa gttctcacga aactttttcc
    78721 agaatagtga accgagcttt ttctcttcat tttttttgta atgataaatc atatacagaa
    78781 ctgttcgact tgcagttcct aatgtgaaaa caggcaagac gcacaggaac catagtagct
    78841 gtaaatggat aagacgtgga atccattcaa tgatttctaa gaaataatca ttggcttttt
    78901 taccaatcga tcgattcatc atccttttga acctcctgtc aaatccatcc cttcaatgaa
    78961 ataacgttgt gcaaaaaaga acagcaaaat cgtcgggatc aagacaagtg ttgctcctgc
    79021 catcagataa ttccattgtg tcgttgcttg gttctgaaaa acttgcaagc caatctgtaa
    79081 cgtgtatttt tcttgatctt ggatatataa cagaggacct aagaaatcat tccaagctgc
    79141 gttgaaggaa ttgatcgcaa tggtaatcaa ggcaggtttc gtcaatggaa gcatcaaatg
    79201 actccaaata tacaaatgat tcgctccgtc gatttcagca gcttcgatca attcattatt
    79261 gatcgataag taaaattgac gcatcagaaa tatattgaac gcattgccga agaacgatgg
    79321 aacgatcagg ggcaaataag tacctaccca gccgatcttg gagaataata catattgagg
    79381 gatcatcgtt acaaaccccg ggatcatcat cgtagaaaga accaaagcaa acatcagctt
    79441 tttcccagga aaatcaagct tcgcaaatcc ataagcaata aaagaatttg aaaggacatt
    79501 accgatcact actagcacag tgatgaataa tgtatttctt gcatagcgcc aaaaaggaaa
    79561 ggcggcaatc gtatccagat agttttccca tacgattttt tctgggaaaa aggtcggagg
    79621 ataacgaacg atttcttcca ttggtttcaa tgaagtaaac accatccaaa gcaatggaat
    79681 gatcaaaatg attcctatta ctgtcatgag gacataactt agtatttttt ttgtttgccg
    79741 attcacactg gtctttttga aataatccat catttgccgt cacctccaga ataatagacc
    79801 cacttaggtg caagcttcaa attgacaaac gtcagaacca acacgatcag aaacaggatc
    79861 attgacatag ccatcgcata acccatatca aaagctacga acgccttgtt ccacatatgc
    79921 agattataaa aaagcaaaga atttgcaggt ccgcctgttc catttttcgt catgacataa
    79981 gcttcttgaa aaatttggaa agaaccgatc gtagaggtga tcacatcgta aaaaataata
    80041 ggagtgatta atggcaaagt aatacttttg aactttcccc aaacgcctgc tccatcgatt
    80101 tctgctgatt catataaaga tctaggaaca ttttgtaatg tagctaagta aagtagcatt
    80161 gctcctccag aactccatat tttcatcaaa atcaacgcag gtttcgtcca ttgtggatca
    80221 aacagccaag ctggtccagg gatatggaac cagcccagaa atgtgttgat caatcctgca
    80281 gatggagaaa gcagctgcat ccataagatg tagactgcta ctcctgataa gactgccggt
    80341 aaatagaaag ctgtacggaa tacactgatt cctttgattt tttgattgag tactgtggct
    80401 aaaaacacac tgaaaatcgt cgtcagcggt acattgaaga tgacgaaata aacggtgttg
    80461 tataacgatt tccaaaataa atcatcgtga acgaacattc ttttgaaatt tgctagacca
    80521 atgaaattca tcttggatgt caaattataa tcggtgaaac taccaataac tgaaaaaagc
    80581 ataggcccta gcataaatac caagaacccg ataataaaag gcgagataaa taaataggcc
    80641 catcttgctt cttttttctt tcggatagat aaacgcttca aattttcttg cctcctctgt
    80701 acctagacag tcaaaaatgg attattgatt ttgcttgact aagttttcta ctgctttttg
    80761 tgcatctgcc aatccttctt ttggtgattt tgttcctaaa agaatctggt caatctgttc
    80821 attcactaat gtcgtgtaat ccggagcatc taaaggaact ggtgtgatca ccgtattttt
    80881 aaagttttcg tccgccattt gatagatcat ttttccttta tccgttaggt tgtcattatt
    80941 cactaaattc tcattggctg tcttgctcgc catgatatca aaactttttt cgccgaattt
    81001 ttcttgtact tctggagaag aaagatattt gatgaattca taagaggcct caggatcttt
    81061 tgctccgtat ggtacttcca agacgaatcc gccaccccac gaccaatggc ctgaaccttc
    81121 ttctttttct gggagctgca tcacgccaaa atcaaaatca tccggtgcat tttccatcaa
    81181 actagagtaa taattgatat tttgggcacg catggctact aatccggaaa taaatggatc
    81241 agatacacca gacccaaatt cggcttctaa tttattgatc gtatttttcc cataataatc
    81301 ttgccagtct tggatccact ccaaggcttc cactttattt ttagtatcaa tcttgacttt
    81361 ttcatctttg tcaaaccaac tagtcccgtt atctgcgttt agcgcccata catcagcccc
    81421 taaattccat aatggataaa aaccgatgcg tgtaaattct tttccttctt ttttatctag
    81481 tttacgtgct gtttcttcta attcatccca agttgtcggt agatcttgtt cactgattcc
    81541 agcttcttta aataactttt tattataaaa aatgacttgt gtatctgtat tgaatgggat
    81601 cgcataagga tcaccttcat attctactgt atcccaaagc tgcggataaa aatccttaga
    81661 agtgtctttt tctacatatt tggagagatt agttgcttgc tgtgcttctg ctctttgggc
    81721 aacggaattt atgtcctgta caataacatc gggtgcattt ccagctgtta ttgcagataa
    81781 agatttagtc cagatgtcac cccatggctg atacttataa tttacatgga tctcgttttg
    81841 tgattgattg aaatcctcaa tgatttcttc gatagcttct tttcgtgcac cggatcccca
    81901 aaaggaccag aaatcaatat tttttcttcc atcacttgtt ttttcagaag aatttgctgc
    81961 acttgaactg gcatcgcttg cattacttga tccgcatcct cctaataaaa acaatgctga
    82021 acttgccagc aaccctgtaa acaataattt tttcatattt tacctccaaa ttttaatgta
    82081 accgatgccg gttttaatat aacgatatca ttttgttctg aaaataacaa tttataaggt
    82141 atgattctaa aaaaattatt aatgatacca atactttata taattcgcga gcgctttctt
    82201 tgaatttttt aatctttcgt agcagaatga gaatgtatta aaaatagatt aggaggaatt
    82261 ttgatgttta gacaccagaa agaattgcag tttgaagcaa aaccagatcg tccgaatcca
    82321 ttaatcgcga aatatctgca ggagctgatc ggcggccaat atggcgagat gagtgtagct
    82381 atgcagtacc tgttccaagg ctggagctgc cgaggagaag aaaaatataa agatatgctg
    82441 atggacattg caacagaaga aatcggccac gtggaaatgt tggcgacaat ggttgctcgt
    82501 ttattagagg gtgcgcctgt tgaagatcaa gaagcagcga tgcaaaaaga tccaacaatc
    82561 ggtgccatta tctctggaat gaatccacag cacgcgatcg tagctggctt aggacctcgt
    82621 cctgctgaca gcgtgggcaa tccatggagc ggtgcctata tcattgcgag tggcaacttg
    82681 ttagcagact ttagagctaa tttaaatgcc gaatcacaag gaagacttca agtagcacgt
    82741 atttacgaaa tgatcgatga tcgtggcgta aaagatatgc tgtctgttct ccttgcaaga
    82801 gatagctatc atcaaaatct atgggaatgt gcagtgaaag aattagaaga aaaagaaggt
    82861 tcaatcttag tcccaagtac tttcccgcgt gacaaagaac gaaaagacat tgcttatgac
    82921 ttctataact tctcagaggg agaccaaagt agtgaaggtt cttgggctag tggcaaagca
    82981 ctggatggcg aaggcgaata tcaatggttg aaagaaccta agatcgaagg cgctgcacca
    83041 aaattagaac cagtaacacc aaaaatgtat gggacacctc cattcaagaa ataaatatct
    83101 acccgtagaa acacccgttt tttgttccac acgctttgtg agcaaaactg actaaagtca
    83161 ttaatcataa ccacccttca aaagggtggt tttctctaga gctataagct caaatcaccg
    83221 gccagcgcct aaagacgctg gctttcatat tttatgttca agccatattg cctttgccag
    83281 ttttgcccac ctcttaaaag gtttatgtac tactccttag cccttaaaag gatcgtctta
    83341 ctctcgtaca ctcagcttat ctaacgcact atcatgtttt tcttgttctt gaatgtactt
    83401 tttgatggtc gcttcatttt gtcctacttt tgtcacatag tatccttcca cccaaaagtg
    83461 tcgataccca aatttatatt ttagatttgc acaatctctt gatgatctcc tgaatattgg
    83521 ctcgatattg attataaatt atttttcttc tatactttgg tgtgaataca atgtggtatt
    83581 tacacatcta ctttgtacgg gctaaactat ttccctttat tgctccaccc gcatagcaag
    83641 tggttttgta tttcaatcgc tcggcgcgct caattaggtc taaagacaat aaatctaaaa
    83701 acccgctgct tcactgacag aaacaacggg ttttcagaaa aaaatgaaat gaaaaagatc
    83761 tcttacggca atctatttta tttttttgat tttttataaa tggaaaatgc ttcaagaagt
    83821 ccaagaaata aagccgtata aaaacaagaa cctatgaaat ctttatttat tagatattca
    83881 acagaaatcc cgataacact agccaacaat atatttatca gaagtgtaaa ataaggatgc
    83941 tttttataga atagaactag tgttgttttc atagactctc ctttcttcat atttccaatt
    84001 aatcacaaat tcacggcatt actagaaaaa ttaaaggggc gcagaagtgg aaaaatactc
    84061 ttcgactttc cctacaaacc aggccatctt gtgtttaata actataccaa atctaaggta
    84121 cctctaaatc taaattccat ttgtggcggt gacctccaat ttttaactct tctatctccc
    84181 atccagtata cataaccttg atacttcgac cacttatata tcgaacacac aaatacctat
    84241 ccattgcagg agtactacct aacttagttg ctacttgcat ctaaataaca gctgaaaaga
    84301 taggacttac tcttagtaaa gtatctgaac tattaatttt taaactatca tttttatcct
    84361 caactacatg cacatctgtt gcaacttcac tttctgtctc atccagataa atgattaagg
    84421 aatcgggaat tgcaatatct tcagctgacg ctggaatagt tgagctaaat tagtcatcat
    84481 atctttatta taaaataacc aacagcaaaa aatacaatga aaaacaaact tggaactaat
    84541 gtatcattaa taaatgttga aaaattcagc aactcattac tgtatgattt tagcagccca
    84601 accaacatat accctataaa agctaataag atggttagga atcctttaga atttttactc
    84661 attcatagac acttccttaa ataactttta ttatagaagg tattgtaaat aataatattg
    84721 acaaaaagtg actcaaaata aaaaaaacct tacattatac tggaatgaac tgtattgata
    84781 gtgtacctaa aagctctact gacataagat cgtgtaatcg gtaaagtaat tttattaatt
    84841 atacgggatg taatcaatta gagaataaac taatcataaa aggtactttt acattcataa
    84901 ttgtcgcttt gagattctac tttggttcac tatctgaccc aattgcacat tttcgatcat
    84961 tacaagtatt ggtgtcgtta gaacaactaa ataaaaacta gcggtagatt tttcagaatc
    85021 tatgctaatt tctgtatgga tgttccagtg atggcaaatt tctcttttca ttgtttttct
    85081 tgtcgcatga tatgcctttt tgtgttattc agttaaacta tagaaattct ttcctagaca
    85141 gatcttgatc ccaaatttta cgtttttgag catcgatata gtttaaaatg acattactca
    85201 tatctaaaga gtttagattt tttaggacta aaactgtcag ttgttctttt tcttctttct
    85261 gttaaagtat tgtcgcgact tttcgtatac gttaagatat gtcgtgaaaa aacaagtttt
    85321 gtgacacaaa aaaacgaatg acttgaggaa atcacctcaa tcattcgttt aaaatgctat
    85381 atattcttta gtttaagata cggaaattaa tgccatcgac cacactagta gaatgaacga
    85441 catttacttg gccttttttt aatttcgtta tgtttagcat ataaaaatat tatagagttt
    85501 acttacaatg cttaaaacat atactgtata atctgatcaa ttttagccat gtcttgcaat
    85561 ggtaagtttt ctattttttt gagttttcgt tccttaaaat caagagattt taattgtgta
    85621 ataattactt gtccttttat atctagctct tcaggtaatg agtaacgtgt cggtaaattc
    85681 tttatagtgg aagtaattgg acatatgacc gaaaacattg ttttacggtt aaattcataa
    85741 cgagagacga ctagtcctgg tcgtcttttt tgaatttctt ttcctacgga gggatcaaaa
    85801 tcaatccata caatatcacc ttttttagga atataaattc tttcttctga cactataaaa
    85861 tttctctccc ttcaggagtt aaatcttccc attcgtcttt ctcataatac tcggcctctt
    85921 ccccaccact aaatggatct tcaatttttg gaactaacgt aattgttcca tcatcagaat
    85981 acacaacgat atattcttgg ttttctgaag gtttctttcc gttatcagaa ggtaaagtta
    86041 ccactacaga acttccttgt aatctagatt ttgtaacaag cattatcatc actcccttaa
    86101 taaaagtata ctatataaca ctaagtaacg caaaattccc ctttgtaaac tatctagaaa
    86161 attgttttgt ttaaagtata tcttattgga tataaataga aataaattgt agccagttca
    86221 ttttttcttt aactaaaaaa ataatccaag aaacattgaa cctatggatc caaaagctac
    86281 ccaaatacta tagctaaccc cccgctacct tcaattttgc agataaaacg ctttgggaga
    86341 aaatttcaaa gacaacaggc catcctatca tgcccgatta taaacaaaaa gctggctatt
    86401 ccttttgctc tgacaaattt caattgggaa agttcacgaa actagcaggt gaagaagttt
    86461 caactgttcg gatcaaagaa tgcccgcttc aaatagaaac attggttcaa cgaatttcaa
    86521 ctagacaaga ctttgctatt gtagaacgtg agatcgtagc tatttttgta gaagaaggga
    86581 ttttacatga tccaactcat atcaatgtgg ataaatggca acctcttatc tataaattca
    86641 gagaatatac aactgccaac cagtcgttaa ctttgaattt tagattccaa gaattcaaag
    86701 agtcataatg ataaacatcg ttaggtataa ataaaaaaga ctcgcagcac gagtaaaaaa
    86761 caaatagaag ctatacatta gaaaggtcga ctgtgaccct atagatgcag tatatgcagc
    86821 ttatgagcat ttcttctgtt ctctttgttt ttgggatctg tgctgaagtc tttttcgttt
    86881 tttgccgctc tttctttgaa aaatcgatta tgttatacct tctccattac taattcaggc
    86941 atctgctgag taatgatttt tcgcgcaaaa gaaatatctg ttacccaagg ttcgatttgt
    87001 tcttcagtca agacaagcgg cattcggtca tggattggtg cgactgtgcg gttaggttca
    87061 gtagtcatta tgattgattc tgccattttt tcatcctgat ggctacgata aaaaccgcca
    87121 atatacacta ttttttcctt atttgaaaac ataaatttgt ctttttcttc attccactca
    87181 ttgggaaaac acaacgattt tgcaaaaatg gttgatgaaa ggtctttttt tcttctactg
    87241 tctctgcacg ggcattaatc atcaattgtc cttttttaaa tccggtaaat ccccacttca
    87301 tgatttccgg agtgaggatg ttttcttcct cttttcttaa cgtcacaaca agatttgacg
    87361 gaaaaacttc tccagctgct aattctgctg cctgcttcgg ttgtttcgtc tgggcttctc
    87421 gataataatt ctgaaggagc tctgactcta gatcaaaaaa ataacgacca cacatcctaa
    87481 tccctcccaa tctttttttc tatcatacac tgcaacaaga agttcgcacc aacaaaacgc
    87541 tttcaatttt tgtagaacta aaaaagttgt gacaagtgac aaactctcca gtgaatggta
    87601 ttctcctgcc aactcctcgg tcacaagtca caatattcaa caaacatgag aagctgcttt
    87661 ttgaaattgt tccttgtgac tcggagtgaa acggcaggct tacgacctct gggtaaacgg
    87721 tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgta gaaagctatt
    87781 ttcacaaaat ttttcttaat actcgaaact aagcgacttt ttcacaacct cttccttaaa
    87841 cggtgttcaa aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tatgagcagc
    87901 tatttttatt tggctgttct tattacttga tgcagggcag ctttttcaca acctctccac
    87961 taaacggtgt tcaatcagct aaccttcggt attagctcaa aaaacggcaa aatatgagga
    88021 actattttgc cgtttgtttc tctaatactc aggtcaaagc gctgatttca caacctctaa
    88081 tacacggtgt tccagaagta gcttcttcga aaaataagcc gaaatttcac aaaaatttga
    88141 gaagcaattt tcgtaaattc cttcttattt cttgaagctg accacttctg tcacaacctc
    88201 taattattaa agaacctttt gcgaagttaa caatctttct ttgatcaatt gaaaattctg
    88261 cctaagtagt gatagatcct gtgtgacttt caacaataag atacttccct ggatttcagc
    88321 aatcaacgct ttggcttgac ggtctgcttc ttcatcggac agtttttctt cagaaagtgc
    88381 caggatattt tgtttcgtat acttgaccca ttgattgact aattctagta gcaacagacg
    88441 gtattcttca tccactgtac tcaactcaat aatcaaatta cctacaggac agccatgata
    88501 agtgatctgt gtctcatgat cagcgaaaat ccagtccaac atttcttcta atgcttcttc
    88561 tggctgtttt ccagcattta agatgtcttc gaacaattct gtctgccata cgtccatatg
    88621 cgcatggatc accgctagac aaacttcttt ttttgaagaa aagtaataat aaaattgacc
    88681 ttttcctgta tcagaagctg ctagaatatc tcggattgac gtttcatgat agcctttttt
    88741 ataaataaga tctttggtcg cttccaagat cttttccttt gttttcaatg atattctcct
    88801 ttttcatttc tcatagtcct atattataca gtaaattcat cattttttct tcttaatcgt
    88861 ttaaaaaaga ctgtgccaaa ttatctgaca cagccctcac tataaaactg ttctcatata
    88921 gctagatgtt cattgattca agaactgcga ggacaaaagc aattcctatc ttatgatagt
    88981 tgctctaata cttcctctgt tgtcatcact tgatctgcaa taaagccaaa gttcgtcaac
    89041 gctgcatcca ttgcttcttg gccaggagca ccaattgcat ctgtcgctac cacaacattg
    89101 aatccactct ctaccaattc acgcatatgg gaatcgctac acaagtttcc gttcattcca
    89161 ccaagaatta ctgtgtcgat tccatttttt ctcaattgga gcgccaaatc attgctttct
    89221 ggtccaaaga ttttatgagg agagctgatg atcgtatttt catccaaata aggtttcaat
    89281 tcttcgataa aatcggctcc tgaaccttct tccactgatt catattgact ttttctagca
    89341 aacatctgct gctcaagcat catatgttct cctgcaccgc caaattgcca tttatggtca
    89401 tgtgggtaaa aataatgagg agaaataaag agtttgtatc ctttttcttt tgcttgtttt
    89461 accatttcaa tcatattttc gatcgtattg tatttttcta agatatcttt tgtcaaacca
    89521 aagccaccgc ctgctggttt caagaactcg acttgcgggt cagtgagaac tactgctgta
    89581 tttttattat tgaacatggt ggattctcca ttcgttattt attttaatac atcatttaga
    89641 gcttcactca ttgtcggatg agaatagatt tgatctctca ataacgtata aggaagtttt
    89701 ccattcatag ctagcgaaat caagttgatg acttcatgag aatcttccgc atagatactt
    89761 gcccctagaa tcaagtcagt ttcagggtcg actaaaactt tgaatacacc tttaggatct
    89821 tctaatactt gtgctttagg gacaccgctt gtcatatact tgaataattt gtaattgacg
    89881 ccttgtgctt tggcttgttt ttctgttaaa cctacattgg ataaagtcgg agtgataaat
    89941 acactgtaag gcacagcttt ccggttattc gttgttcgtt tattctcgcc cttcaactga
    90001 tccataatga ttcgataatc atctagagag atataagtga actgcaatcc gcctttgacg
    90061 tctccaatcg cccaaatgtt gtctgcatct gtacgaaggt attcatccac agcgattgct
    90121 ccgcgatctg ttagtttaac atctgtattt tctaatccaa gtgatgctgt acttggtttt
    90181 cttccagttg cagccaaaac ttttgacgct tggattgtta cttcttggcc atcttctgta
    90241 aaggtgacgg cagctgttga ttcttggtct gctacttgat ctacagatac acctagatgg
    90301 aattcgattc ccgcatttgt catgtcttct aaaatcattt gcgcgatatc ttcatcttca
    90361 cgtggaagaa attcagaatg ggcatcaaga acgacaactt tagatccgta ttcattgaac
    90421 attgatgcaa attccaagcc aatatatcca gccccgatga tcactaattt ttccggtaat
    90481 tgttcctgat ccatcgcttg cgtagaatca atcaagtagc gacttgtatt caatcctttg
    90541 attggtaaaa tgattggttc agaaccagta ttgatgaaaa tccgttcgcc ttcaacaatc
    90601 actttttcac cattattcgt cacttcgatt tgatggttag aaagaaaacg tgctgtaccg
    90661 tccatcactg tcccagttgc ctcatcgctg atcatatgat aatttttggc gcgaagcatg
    90721 cccgtcaatt tttctttccg agcaacagcc tctgtaaagt cgattcctct ttctccattg
    90781 aaaatcaatg atttagaagg aatacagccg atgttgatac atgttccgcc atacatacgt
    90841 gttgactttt caacgactaa aaccgattca ccttttgaag ctaacgcctt cgctaaagtc
    90901 ttaccgccct ttccaaaacc gatcacaata ttttgatatt tttccatcat ttttccctcg
    90961 cttctttttt acctaccgat tggtacaaaa atatgataac cgataattgt ctattctcca
    91021 aatcatctgc tttatttgtc aaaaaaaacc agacaaaaag cggtcctttc acgtttttag
    91081 tctggttcga tttcctttat tcttctaaac aatcgttact tctacatcga tatttcctct
    91141 agttgctttg gagtaagggc agaattcatg cgcatcttct gcaatttttt gggcttcttc
    91201 ttcgctgatg ccatcgatat gcacttctaa tactacaccg atctgatagc cgccatcatc
    91261 taaattataa agagagacac gtgcttttac tgtggactct gctgtcattc ctgcttcttt
    91321 gatcatatgt tgtaccgccc cattgaaaca agaagcataa cctgctgcaa ataattgttc
    91381 tggatttgtt ccttctgcat ggattcctgg aggagtgatt ttcatatgca tcgagccatt
    91441 tggtgcctcg acttctccat tgcgcccgcc atggttgatc attgctgttt cgtatgcttt
    91501 tttcattgta ctgctccttt cgattgacca tttgctactt ggctataatt atagtgtatg
    91561 acaagtaagg cgctttctac aaaaattctg cttattcgaa taccagaatg ccgtcttcta
    91621 ctatttttcc aaaaaacaaa aaaatactac tcgtgaacaa cagcgtcata tttgttccaa
    91681 aataaatagc aatcttttct acataatctt ttatatgatt gattttaaga tacatatata
    91741 ccagaaagtt gaccccataa accaatactg ttaaaaaaat aaccatattc gttaccattt
    91801 tttcctcctt ttgctggtct ccctaccagc actcgattta accataccac tttttttgcc
    91861 gtccaagcaa ctagcctttc aaaaagactg gtttattctg ctgttaatga ttcaagatca
    91921 gaaaaatgtc cgaataattt tgctaatttt actaacgcca acttgttctt tccgaattca
    91981 tcattttcta tctgtaatac tagtaacggc tcatgtaagc ttaaacggat caaaaaccag
    92041 ccgtttccgt atggctcttc tagatcatat cgaatacctt cttcattttc cgggtcgaag
    92101 ttcatccctt tttcttcttc caacagtcgc ttcatttctt ctaatatctt gtttccttgt
    92161 tcgcgtggtt catcgctgaa caattttaat cggatttctt gtacttctac gggctgtttc
    92221 aactctttga tttgttcatc taatgtgata ccttttcttt ttaattctgg caaaagcatc
    92281 aggatctttg cgatgacata tgcaccatca tccagaaaat agttttcctt gaatgcagcg
    92341 tgtccgcttg tttcgatggc tagctgtgta tctttcccaa gacggttaag ttctaatgct
    92401 ttattgatta catttcgata gccggaaata taacgaactt ggatgcctcc tttttcttca
    92461 atgaatcttt gtagatgaga agaagtaggg gaattcgtca cgattcttgt tcctggatgc
    92521 tcttttaata cgattgtact taatactgcg atcaaattat ttcgattgat cactgttcca
    92581 gaagcactga caactgcaga acgatccaca tctgtatcga aaatgatccc aagatctgct
    92641 tcatttgcta aaacagcctg cttgatactt tccatcgctt ctttattatc aggatttggg
    92701 atatgattag gaaatcggcc atctggttcc aaaaattggg aacctgttga atccgcacct
    92761 aagctattca atactttttc agcaaagaat ccaccagcac catttccggc atcaacaatg
    92821 attttccaac catttagtgg tttgctttct agtgttccaa tccccttttt aatttttgtg
    92881 actaaatctt gcgcataagg tgtcaaaagg tctgcttttt ctacgcttcc agtttgttcg
    92941 ctttttattt tttgctgctg tgataggata aaagcaatat cttctttttc tgctcctcct
    93001 tctgaggtaa agaattttat tccattataa taatagggaa gatggctagc agtcagcata
    93061 accgcagcat cgcacgagaa ctgttcaaat tgagtggaca taaacatagc aggcgtagta
    93121 gctaattcga aatcgatgac atgtatccct tgttctttca gactttggat caacgcctct
    93181 ttcagtgctg gtccgcttat cctactgtca tgaccaatcc caatcgtcca ttttttattt
    93241 ggatcggttg atttcttctt tttctttatc cagtttgcta gtccccagcc gatctttttt
    93301 accatgtctg tcgtcaagtt tacttcatat ccttcaactg gtaatgcgat tcctcgaata
    93361 tccgatccat tttgcagcgc tttcatatct ttcatataaa agtcctcctc atttattccc
    93421 tcattttttc cagcttttct gcaaatcgct gtgcttcttc ttctgagcgg caaataataa
    93481 tgaatgtatc tacaccggcc atcgttccga caacttcagg gtaagccact tcatctagcc
    93541 aattcgttac cacatcggca ccatttcgtt cagtcaatac gataaccatg aactgaacag
    93601 actggatacg caaaacctcg cgtctaattg ctgtacgcaa acgttcttca tttaaagaaa
    93661 cagatggctg gttaaataat gtatagcgta ctattttgtt ttcattttga ctttttacta
    93721 acttcatttc tcgaatgtct cgagaaatcg ttgcttgagt cacatcggcg cctgcttcat
    93781 gcagccgcgc aagcagctct tcctgtgtcc caataggttg ttctgtaatg atctggcgga
    93841 tcagtgcttg tcgctgtttc tttttcatat tagacacctc tcaatgttga ttatagcaaa
    93901 agataagtaa tatttcttca tattttggta ttttttactt ttattttttg ttttcattca
    93961 ggttgctaac ctttttctat tttaacacgc aaaatcgtct tcattttttc aggtgctgat
    94021 tttcttggat cgctgatgta aatctctttg tgttctttag aagctctttc atagccttct
    94081 tttgcgatga atgcttctaa tttctcaaac gttgctggtt cttcggcata gggcccgacg
    94141 tgtaagattt gggcacaaag accttcttcc atctttttga atactacttg ttctttcaag
    94201 tcttccggaa gtttgctaga acgctgaatg gcttcttgtg ctatcgcttc tgtaacaaag
    94261 tcaggctgtc ggatcatcaa ttgataagaa aaatgttctt ttttcatcac tggttcatgc
    94321 aaatactttt cttgcagtcc ccattgtcct tccagtggat agacagtata catctgataa
    94381 tcaggaatca gccaattttt tttaggcgac atgcgtattg catagctgac tgcatataga
    94441 caggctactc ttcgtttaaa gtcttcctga ttcgggtcgc cgatccctct gatgctaaag
    94501 aatgattttt taggaacctc tagtatttgc gggctttttt tcatactata gctcttgtct
    94561 ttacgccatt caattttttc catttttctt cctccgcgaa attccattta gttatttatt
    94621 atcatacctc tttttgagtg acttggctaa tcgtgttgac actatttttc agtttgtgct
    94681 agaataagtg aagtaaataa atcgtacaga taacacgttt cggcgtgtcg agagagaggc
    94741 ggtttctatt tttataatag aaatcactct ctttttttac gaaatttttt agaggtgatg
    94801 taaatgacaa aacaaaaaca gctgctttta gtacctgcag taattgcaac agggatgatg
    94861 tcttttgcgg gcgtattgat cgagacggcc atgaatgtaa ctttcccaac tcttatcaga
    94921 cagtttgatt taacgactgc acaagtccaa tgggtaacaa cgatttatct tttgatgatt
    94981 tcgatcattg ttccgctgtc tacttatttg aatcgcaatt ttagtctcaa aaaactcttt
    95041 ttagcttcaa atctgctttt cttggcaggt ataatgatcg atttcttctc tcctaccttc
    95101 atggtcctat tgtttggtcg attgctccaa ggtgcagcga caggtatcgc tcttccgttg
    95161 atgttccata ttatcttgac atttgccccc ctcaatcgac gaggcgcgat gatgggtgtc
    95221 ggtactttga caacggccat tgctccagca attggcccca cttatggagg cattatgact
    95281 tcacatttta catggaatca tatcttcctg tttcttgtgc ccgttttgtt tctttctttg
    95341 attatcggct ggtttgctat tcccgagatg gcagtacaaa aaagtggtta tttggattgg
    95401 ataagcgttt taggaatttg tcttttgttt agtggaagtc taacattttt gagtacgttg
    95461 ggaacagttt ccagctggat tgctttaatc atcggcggta ttggctggtt ccttttttac
    95521 tatcgaagta aaaaagtgga gcatccactg atccgactgt ctattctttc aaataaaaca
    95581 ttccgcttgt ttttgattgg cttcttagtt tatcagtttt tattacttgg tgtatctttt
    95641 gtcttgccga atttccttca gatcgttcaa ggaagtagtc cttttgtcgc tggattagcg
    95701 atgcttcccg gcgcagcggt tggtgctttg ctttctcctt tttccgggaa aatgctggat
    95761 caatatggtc cgaagaagcc aatttttgct gggctgattc tttctttgat tggttggcta
    95821 gcattattcc tactcatagg acacgcttca gtgggtgtat tgattgcttg tcatgtgttt
    95881 tatatgatcg gtatcggatt atcttacagc aatatgatga ccaccggaat gaatgcactg
    95941 aatgaagaac tacaaggaga cgggaacgca atgttcaata ccttgcagca gttttctggc
    96001 gctgtggcta cttcattagt agcggtcatt atcaattacg tccagcatca tacttcccat
    96061 aactatgaag tgtctactac attaggatca aaagcagcat taggcgtctt gttgctgttg
    96121 cttctcgtaa gctttgctcg attcgcctat tatctgttct ttgctaaaaa agcgtagatt
    96181 ccatatacgg caggtgttgc atctgccgtt tttttgtgtg aaaatggttg tttgtaaaag
    96241 gaggcttttt tatggaaaaa attgccatta tcggtggcgg gatcattggt atgaccctag
    96301 ccagttactt agatacatca aaattcaatg ttgctttatt tgatgaaggg acaggacagg
    96361 caactaaagc tagcgctggg attatctccc cttggttgtc gaaacgcaga aacaaacaat
    96421 ggtatcgtct ggctaaagac ggcgctgctt ttttccctaa acttataaaa gatttccaac
    96481 ttgatcaaac gatttacgca caatcaggga cacttttgct tcgacctgaa aaagatttag
    96541 ctgaattggc tgttcttgcc gagaaacgaa aagaagaagc gccagaaatt ggaaacatcg
    96601 aatggctttc acctgaacag acatctcaag cacttccgtt attgaaacca gcagtttcac
    96661 tgcgtatcag tggtggtggt cgtctggatg gaaaagcata tttagaacat cttggtcagc
    96721 gtttagcaca aaaacaaatg gagcagatcc aggcaaaagt cactttgcat aagaagagcg
    96781 attcttggct catcaaggga ccgtttggag aatacacagc tgatcgtgta attttgacac
    96841 ctggcccggc acttaagcct ttattacaag aattaggcta tgctgcagat atacgtccgc
    96901 aaaaagggca gctcttagca tttcagacat cttataagat gagtcaagac tggcctgttg
    96961 ctatgcttga cggagaagct gatttcattc ctttcatgga tggaaagatc cttttaggtg
    97021 ctacccatga aaacgatcaa ggctgggatt tggctcctac tagcgaagct tataagggat
    97081 tgactaagag tacagaacag ttcttgactg atccagatca gataaaaaac tggccatacg
    97141 agttccgtgt aggtacccgt gcttatacgt cagatttttc cccatttttc ggcgtactgc
    97201 cagatgatcc aagcttactg gctgctagcg gtctaggctc ttctggcttg accacaggtc
    97261 cttatatcgg ctatctatta gccaacttct taaatactgg tcattggcct acggaagatt
    97321 atcaaaagga catctccacc tatattacga aaaatccatc atagaaaaac agctttttca
    97381 agtaaggatc ccgagcgata ttgcgcatgg attacttctt gaaaaagctg ttattttagt
    97441 tcaatttctg aatcaaattc tccaaacttt cttttgcttc atctggcaag agatcttttc
    97501 ctatctgagc ttcaatgaat cgtaaacgaa tatcaagtcg ttgtttcacc agatttttat
    97561 aggacgtatc ctcaaaagaa acaggaaaat ctggtatagg taaatagtgg atgtcttcaa
    97621 atggaccaaa cgacttgaat tctgccgttt gttgcacgat tctttcaacg attgacaatg
    97681 tcgtttcagg tttgattttt ttatcatcga aatatccagt attcaggaca tagcaggctg
    97741 tttgctgttt caaaaacaac tctcgaaaag cttgatagtc ttccctaaga ggatagacac
    97801 ggaaaggatt agcaaatggt tcaatgacta gctcatctag ctgtcttttt gtagtgatat
    97861 tttccgcgtc tgatcgtttt gttgctaatg ttgcaccaaa agacgctgct aaaactgggt
    97921 cattgatctt gataattggc ggaagcgaat catctttcat gatccaaaaa acagcatcga
    97981 tcttttcgct aagatgatcg actcggtcgg gtgtcgcata acgtgatttg actgtccgcc
    98041 catttccgtt tcgtatatct cctgttacta ggactttttc tcctttactt gtacatgtca
    98101 cgcccacatt ctgacaagta aggaaagaag aaatggccgg atcatcagac ggatagtctt
    98161 gtgttttatc aaagtaagaa ggttccaagg cagtagcaaa accatttttt cgagaaataa
    98221 cgaaagcatc gtcatgcaag atcgaaacag agtgaccttc cgtatgtttt gctaaggtaa
    98281 tcgttgattt tccagaaccg gacaacccaa atacagccat cgtataggtc tggtcattac
    98341 tagcatattg tttcatccca ccgtggcagg caataaagcc attgcgattt cccaatgccc
    98401 aagcaagcgt caaagtcgct ttttttaatt ctccaaagta acgtaatcct agcacagccg
    98461 ctgtattatg gagagcatca aacaaaatga gtccatttgg aaatgtttca tgtgtccatt
    98521 cgggatcaca aaagatataa agatctccct catcaaagga aacagacttt tgataagtct
    98581 ctaagatctt cgaattcgct ggctgaaaat tcagcaaata agaatacaaa ttgttctcaa
    98641 atccttctgg aatcagcaaa tgactttgca cagaaaattc ttcagatagg ccaacgatta
    98701 cttttgtatg gtaaaactgg cgcttgcgac tttgatacac agcttctctt aaaattttct
    98761 cgtatttgct ttgttccttg tctaagtcct caaagatccg ccgagcactt gctgttcttc
    98821 ccacaatgct tccatcattg aatactagtg tcctaacatc agctggtaaa tctagttctt
    98881 cagcatgtga gattgttaaa tctgtgatga tcgttcctgg actccctttt gctagttgat
    98941 aagctgtctt cctatcaaaa acttcatgaa cattattacc gtaaaatgtc gtttctacaa
    99001 tcgatcgaat actggataac agtggatttc cacttgtgat ttcgtttaat tcgagactct
    99061 cttttgtact catggctcct cctcattccc taaacaaaaa aacgttttct ttattataca
    99121 ttattcgagt ttttatttgt actgctgcgc tgtgggaagc aaacgagtta tttttcacac
    99181 aaaaaaaccg agaacttgaa taaacaagtt tctcggtttc atcattttcc ttttatcggc
    99241 ttagtaccag ccgtttgcta accagaatgt tttagcagca tcccatgaac cataacgaga
    99301 tgttacatat tgttctgcta cacgttcttg attggcagct gaatagtcgc cgtttaagta
    99361 tgaagcatct aattgataac ggccgatgta acgtccgtta gtagctgtgt atgaaccgcc
    99421 tgattctttt tgtgcgatcc attcttttgc agagcttgaa gttggcgctg ttgcagcagc
    99481 tggggcagca ggagctactt caactgtttc aacaggtgca acgtatgtat gttcttgcgt
    99541 tgctgtttca gttgtagatg ctgtattttc tgttgttttg ttttctgttg ttgctgaaga
    99601 atcatttgaa gttgggattg ttaattgttc accaacataa atgcggttga tgtttgcgat
    99661 cgaatttttt tcagcaattg catcgatcat tgagttgtct cctgcaaatt tttgtgagat
    99721 cttagataat gaatcacctg attttactgt ataaacttca tcagcgtgag catttgtagt
    99781 tcctacaaac attgcagtag caccagcagc aaaagttgta cctaaaacaa ttttcttaaa
    99841 tgaattcata ttaaactcct ttttttctcc gttttttatt ctttcgacgc tattaacttt
    99901 atcatttaga aatatttcat aggtaaaaga aacatgacat ttaatgacaa aataacgaat
    99961 tatttaatat ttgtaacatt taaacaaata tttttttgat acaaaaccat aaaagccttg
   100021 ttgtataagc aaagtaatcg tttttctatg tttttttatt tttgaatgaa aaacgcagat
   100081 tctgtaacat tcactgcaat aatccataaa aaaaagcaaa aaaatttttg atttttatca
   100141 aattctctta aaaaaatgta aaaaatacaa aaaaaccagt aattgttaca acaattactg
   100201 gacaaaaact ttgaataatg ttaactattt ttttatttta actttctccg caataatttc
   100261 tgggcatgtt ccaattcgtt tataacgact tcttctgttt ctttagctaa tatttcatct
   100321 aatacatcaa gccatttttc cggttctttt gttcctagac gtccaatagc ccaagctgct
   100381 gttcctctga tgacagggcg gacatctgtt aaacattctg aaatctcagg caatgccgtt
   100441 cgatcaccta gattagctaa agcaatcaat gcgtttctct gcaaaggttt cttcccacgc
   100501 catgaaccag ctaaatgccc aaattgctgt ttgaagtctt tattagacat cgaaagcatt
   100561 ggctttaatt ttggatatat ttcgtctact tttggttcca tctcttcatg aaaatgaaaa
   100621 tcttttcctt gattgtaagg gcagactaac tggcagatat cacatccata aatgacattt
   100681 cgcatttttt tacgatattc ttccggcatc atcccttttg tctgagtttg ataagacaaa
   100741 catcgctggg cattcattct tccgtcacca agcaatgctt ttgtcggaca agcagtcacg
   100801 cagcgcatac agtcaccgca accaaattct cctggtttat caggctcaaa tacaatatta
   100861 gtaacgatct caccaagata gacaaatgaa ccgaactctt cagtgatcaa caatccgttt
   100921 cgtccaataa atcctaaacc agctcgctgt gctacagcga catcgatcag ttctccagta
   100981 tctacttgcg gagctagacg ccattcctct tctttttgcc atttttctgc tcttgtttgg
   101041 atgaattcga tcaatcggtt caaacggtct ctgagtatat catggtaatc gatcccccaa
   101101 gaagcacgag caaactgccc gcgtttttca tccctaggca cttcttcatg gatcctagta
   101161 ggatacgcaa gtgcaatgga aatgatcgat ttcggctgat caaatgtcat ttctggataa
   101221 agacgctcat cgatatttgg atgttcaaag ccagaagtat ggccagctgc tttttgttct
   101281 tccaacgatt cttttaatga atcaaaaggt tccgccgtgg tgaacccgat tttgtcaatt
   101341 cctaatcgtt tgctttcttg tatgatttct tcttttaatg tcatggtctt cctcgcttgc
   101401 tgttaacggc tgtataaccc ataatatagt ttttcttttt tcagctggac aaactggatc
   101461 tgctgatcgg caatcttctt ttcttccatc catttttttc ttgcagcaaa tacttcccaa
   101521 taatttgttg aaattaattt tcttttgtta tctaatgcat taaaaaaatt caatgaaact
   101581 ggttttgtac ttaacagttc atggagcctt acctcttccc atggcgaaaa ctcagacaga
   101641 tcgcgggaat acaatacttc ttcatagaga tttttttgct gtgtgtacgt gaatgtttgc
   101701 gggattttcc caggcctagc aatttctact agacgattat aaaacatatt cattaatttg
   101761 ctgttggcaa taaattgact tttataatag gccgactgga tctttttgat tactccttct
   101821 gctttgatga ctgaaaataa tgcaggccat gctttgacgg ttatttcgtc gttttgttta
   101881 actaatacgc caggtgtgaa gccgactgga gaaaggaaca caaaataacc gataccggta
   101941 ttttcatcta aaggctgaaa ttcatcaaac aaccatttgc ctatgtacag ctcttcatct
   102001 ggttctgttg tctcattttg atttgctatg aataatttag ctaattctgc ttcaagaaat
   102061 tgaaggtctt gatccttgtc ggtattttcc tgctggctga tcaatcgaaa gacttcttct
   102121 ttaatcgtat atttatcttt acgtgtaaaa ttcatagcca caccttcctt ccttactcta
   102181 actataacgg aatttcttca aaaaaggtat ctgtacgacg aaaaacagca taattttttt
   102241 tcatatctct tataaaaaat gcaaggtctg ctcctcaagc tagaccttgc acttttcagc
   102301 tttcttttgt ttgtgacaaa ccttcatgga tcgtttcaat attccatttc atcatctgat
   102361 agtaagaatc tccttgttct ccttcttttg ctatggaatc agtgaacagt ttatcataga
   102421 ttttcaaacc cgtttctttt gctacccgtt ccatgcttct tgagtctaca ctggtttcca
   102481 cgaataaaac cggtacttct tttgctctta tctgatcaat gatcgctttc atttgatcag
   102541 gcgtaccttg actttctgta ttgatctccc atatataagc tgctggcaaa tcatatgctc
   102601 gtgaaaaata cttgaatgcc ccttcacttg ttactaataa ttttttgttc tcttcgatag
   102661 aagcaaaact ttccttcgct tgtgtatcta attcttttag tttttccaca tatgcttctg
   102721 catttttttt atagagtgtc gcattttctg catctttttc agagaatata cgtgcgattt
   102781 cctccacata ttttattccg ttagataggt ctagccaagc atggggatct gcttttgtat
   102841 gttcttcacc gctagttaaa taaagaggtt ctacattttt gctaactgca aaataatctt
   102901 ttccttcttc ttttttagcc gtttccatca agttatcgaa ccagctgtta cctgtttcaa
   102961 gattcaaacc gttgtataaa ataacatctg catcgcttgc ctttttgatg tcttctggta
   103021 gtacttcata ttcatgcgga tctgttccga ctggtacgat actgtggata tctatttgat
   103081 ctgttccgac ctcttttgcc atgtccgcca agatcgaatt ggtagccacg actgacaact
   103141 tttctttact tccttcatcc gcttggtcag aagcctgctt tccgcaaccg gctaatacca
   103201 agaaactaac tgccaagatt aaaaagagtg atttttttgt tttcatctat ctgcttcctt
   103261 tctgaaataa aattcctttt gttggagaaa ataaaaaagc aaggataaaa aatgcggtac
   103321 atgctaacac gatcgtagct cctgatggcc aattgtaact ataactgaaa aacacaccga
   103381 caactgcact tagcataccg attcctgcag ctgtaatgat cattttcagt aaatggttcg
   103441 ttagcaagta agccgtggcg gctggtgtga tcaacatggc aatcaccaag attgttccta
   103501 ctgtctgtaa actgactaca gccactaatg tcaaaaagaa catcaaaaga taatggatca
   103561 gcgatgtgtt cagcccataa gcttttgcca ttgtcggatc gaatgatgtg atcttcaatt
   103621 ctttataaaa gaaaaagaca aatatcaaga cgattccact aacgagtgct gtcagcaaca
   103681 aatcgctttc cctaacagct aagacattcc caaataaaat atgatacaaa tctgtcgcac
   103741 tctgggcata tgaaatcaag ataatcccta atgcaaaaaa ggagctaaag acaattccaa
   103801 tcgctgtatc atttttcaat cggctccgct gagtcacgaa accaatcact gctgctgtta
   103861 gcatcccaaa agcagtggct ccaaagatgt aactaaaacc aaacatataa gaaatggcta
   103921 cacctggaag aactgcgtga gagatagcgt ctcccatcaa agacatccct cgtaaaataa
   103981 taaaagaacc gatgactcca gaagcaagtc ctacaagcat ggaagtgacc aaagcgtatt
   104041 gcaggaattg ataattcatt aatccatcaa taaaggattg gatcattttt tctctcctcc
   104101 ttttactaaa tgtctgatga tctcaccata ggccaattga aggttcttcg atgtaaagac
   104161 ttcttgtact ggaccggaag cgatcagctg tttatttaaa agaataacct catcgaaata
   104221 ttcttctact ttatgaagat catgatggac gatcaaaatc gtttttcctg aattcttcaa
   104281 ttcctgcaag atgtcaaaga tctttcgttc acttaacgca tcaatcccta cgaatggttc
   104341 atctaaaaag atccattctg ctccttgggc tagagctctt gcaataaaaa ctctctgaag
   104401 ctgtccaccc gatagttcgc tgatctgtct tttggcatat tcttccatcc ctactttttt
   104461 caaagcttgt cttgcacgtt ctttttcttt tttcccaggt ctttgtccaa ttcgtaaaga
   104521 tggatatgtt cctaaaagta caacgcctaa tacatcaatt ggaaaggaaa gatccaattc
   104581 acttcgctgt tccacgtagg ctattttttt acggactgag tttaccgact gtccagaaaa
   104641 ggtgacttta ccagtagtag ctggtatcaa ctctagcaaa gatttcataa atgttgattt
   104701 tcctgcaccg tttggtccga taataccggt aattttttgt ggatttatcg tcaagttgat
   104761 agttttcaaa acagttttcc cttgataagc ggctgaaagg tcttgaatta caatggccgt
   104821 acgttccaaa tcttacactc ctttttaggt ttacctaact ttttatttaa atatagttta
   104881 actaaaatgg aaagcatttt caagtagaat gatgaaaaag tttttttcga attttcctcg
   104941 cattttatga aaattttctg tagaatcaca tcaagagttc aataaggcta acctaataat
   105001 gaaaaacatg tgttgaaacg tttgattatt ttttcttgtt gactcaacaa cgaaaggagt
   105061 ttttgtatgg aagaagaaaa gttaactcga agtcttagtg cccgtcatat ccaaatgatc
   105121 gcactaggtg gaacgatcgg tgtcggtctg tttatgggtg cctcctcaac catacgttgg
   105181 acagggccct cagtgatggg agcctatgcg attgcaggat tctttttgta tttgattatg
   105241 cgtgctttag gcgaaatgct ttacgttgat ccttcgactg gttcttttgc aaattacgcg
   105301 agcgagtaca tccatcctgt ggctggctac ttgaccgctt ggagtaatat ttttcaatat
   105361 attgtcgtag gaataagtga agtgattgct gtaggatctt atatgaatta ttggtggcct
   105421 gatttgccgg caattattcc cggaatcatt gtcgtcttgt ttcttatgct ggcaaatctt
   105481 atttctgtca aggcgtttgg cgaattagaa ttttggtttt cgatcatcaa agtcataacg
   105541 atcattttga tgatcattgc aggtcttggg gtaatcttat ttggatttgg taatcatggt
   105601 caggcagtag ggatttcaaa tctttggaaa aatggtggat tcttcactgg aggcgtcaaa
   105661 ggatttttct ttgcattatc gatcgttgtt gcttcctatc aaggaatcga actgatcgga
   105721 atgactgctg gtgaagcaga gaatcctaaa aagacgatca ttgaagctgt ccagtccact
   105781 atcggtcgaa tcttgatttt ttatattggt gctattttta tcattgtgag tatctatccg
   105841 tggaatcaat tgagtgagat tggttcacct tttgtacaaa ctttttctaa agtcggcatt
   105901 acatttgctg caggactgat taattttgtc gtgattacag cggcattatc aggttgcaat
   105961 tcagggattt tcagcgcaag tcgtatggtc tatacacttg ccataaatgg aaagatgtct
   106021 aaaaaatttc tgaaactatc tcgtcacggt gcgccttttt atcctgtcgt agcaatctca
   106081 ggtggaatct taattggtct gatcttaaat tatcttctac caatgttcat caaccagtca
   106141 gaaaatattt tcgttttcgt atacagctca agtattttgc ctggtatggt tccttgggta
   106201 gtgattttga tcagcgagat tcgcttcaaa aagaagcacg cagataaaat gcatgatcat
   106261 ccttttaaaa tgccactatc tccttatacg aattatgtga cacttgcttt tttagctatc
   106321 gtattgattt tcatgtttat caatcctgaa acgagaatct cattgattat tggactcgtt
   106381 ttcttgcttt acatgacgat ccattacttt gtacgcgaaa aaagaaccgg aaaataaaaa
   106441 aagaacgaag cttcacctta gtggaagctt cgttcttttt tattgctttt atcaattcaa
   106501 ttttagcgtc tcaccgggag tcaggaaata attctccatg ctcatcccat tcagcgacaa
   106561 gatcgtttct actggtacgc cagttcgttc ggctatttga tttggacctt ctccttccaa
   106621 aactacggtt gtcgcagcct gtgaagtcgc gctgttggta ttagtttcag aggaatctgt
   106681 tgtgtcttgt gttgttcgag cttgcatttc agaagcttct accgactctg ctgtctcaga
   106741 atcagaagat gttgtgtctt gtgtgcttgt tgactctgct tgaagagagg cgctagtctg
   106801 caaataaata tcggaaatct tagcgacatg attcgtataa ttagccgata attgattgat
   106861 caaagtatct aagtctacac cgtctttatt ttctgctgcc tgatacgctg cacgtaattt
   106921 tctgatccct tcgtcggaga ttgcttgaag ctcacgtgct ttttggttag caactgctga
   106981 taaaccagct attccctctt gatttccctg aatttctgtc tggtattctt caatcaatgc
   107041 aggcgtcttt tcttcgatct ttttcgaata atcatttacg attgcttgaa gttgctctgg
   107101 caaaccattt gctgtttttt cttcagaagt ttgtgtctct tttgttttag ttgatgactc
   107161 acttgtttgt ttcgtctctg ttttctttgt cgttgtttcc gttatggtcg tacttttcgc
   107221 ttctgacgaa ttttttccat gaaaatatag acccgcaact cctcctgcta tgatcaaaaa
   107281 cacggcaact gctgccccaa tcatgatcat ccgcttacga gctgcctgtt tttgctgtct
   107341 tcttcgggtc atccgaacat tttctcccca ctcattttca tcatacattt ttttcaccac
   107401 caatttttat gtataatagc gttatcaaac gcttcatatt cttattgtag caaataattg
   107461 tcgctgtgca catttttatc tttgttattt ataagaaaat ttcaccagtt gagatgattc
   107521 caagattgtc cgtcgatttc tccttgcagc tgcattgttc gttcgtctat ctcagccatc
   107581 agtttcttta tttcatataa gagcgcacgg tcttgatatt ctgatttttc gcttaattca
   107641 tctaattgtt ggatcagcca atcatttgtc ataatgaagt tcctttcatt tcttgcagtg
   107701 taaaggtcaa gtcttcgatc tgctcttttg cctcagtcag tgcttctacg atatatgctt
   107761 gtttttcaga ttcttcttcc tgcattttct gattttcctg tactctttga ataaaccagt
   107821 caatccgctg agtcagcgat ggtttgcctt ccaatgagag atactgctga taagcaatta
   107881 gcttctccca acgtttttcc tgggataaat acataaattg tgctaaaacg aatggcggaa
   107941 gataggtcat atggaattta tttgcgattc gctgatacgg cctcaaaaat tcggaaatcg
   108001 tatattcttc ttttcctcca gcttggtatt ctttttccgc cacacctgtt gtcaatacga
   108061 ttcctagttc tttccctttt aatacatgtg ctgctcgttc caagacatta tcttgccaaa
   108121 tttttaaatg agcaggagaa ctataccagt aaaacggaaa ctggaaaatg atccgatcat
   108181 gctgggccaa gagctgtagt tcagtctcta tatctatttt tccgtctgga taacttgatt
   108241 ccaaatgatg ccaagtagct ggtaaaccag cagaagcttc tttgaaaaat tgctgattta
   108301 aagattcttc gatcgttgga tggctaatga tgataagtgt acgcatccct tttcctcctt
   108361 tttagtcttc gctttacagt gtagcataac cgccacaagt ttcttttgcc gatgcttgtc
   108421 attttaacca gactaatcag gttgtccaag aaactgcggt ttgtttttcc aactgttttt
   108481 tcaaggtatc caaagcaata ttcttaaaat tttcgttttt catacgttta cgatagttcg
   108541 tagccgtttc tccggtactc tttttgaaca ttcggctaaa tacgactaga ctattgaacc
   108601 ctacttgata ggcaatactt tccacggatt catccgtcag agaaagaaga aacgcccctc
   108661 gattgatccg taccccgatc aaatattcct tgatactggt acccatatga tttttgaata
   108721 ctcgcgacaa atggctccga ttgaccgcta aatgctgggc gatttcctca acagacaatt
   108781 tttcagcata atgtgcctcg atgtatttga ctgtttcaac agctaaagag gaatgaacct
   108841 tttgtacacc accgctgacc tttccgccat cttttaaaag gactgataaa aaacggtagg
   108901 ttaatgctgt taactgtaat tcattttcca aggtttcttc cgtatctttc atgcattcta
   108961 aaataatgtc gatatatttt tgtatgtcag aagagaccat cgtgtattgg tcttctctga
   109021 aaagcgactg ccgaatgatt tcttctgcag cactcccacc aaatgaaagc cagcaataca
   109081 tccacggatc ttctccatct gataagtaaa acgtcgagtc tcctggacga atcaagaaca
   109141 gatcaccttt tttcaattgg aattgttgat ttttcacatg ataagatcct ttgccttcca
   109201 tcacgacatg caggatgtaa tcattgcgaa tagcaggacc aaaagaatga aacggcatcg
   109261 ttttagagaa accacaaaaa tcaaaataca attctttttc tacttgttga tgttcctttt
   109321 ttaaaaaaat cgattgctcc acgtctatcc ctccttactc ctttagtata atgcaacaaa
   109381 aagttaaata aaagtcacag aaatatatta aaaaggaagc gatttcttgt taagtttaag
   109441 tcattaaaag atctttgtta ttcgttgtaa ccggtttact tagtattata tattgaacag
   109501 gagaggaata cagattatga aaagcaaaat gatccaacgt gtgtcctacg ctttaggcgc
   109561 ttttggacac gacacattct atgttacatt aagcacttat tttatggtat tcgtgacaag
   109621 ccagatgttc gcaggaacag ataaggcaac gaatgcaaaa atgattgcta cagttacaag
   109681 cttagttgta ggtatccgct tagttgaaat tatttttgat cctttgattg gtggcatcat
   109741 cgataatact cgtacaaaat acggtaaatt caaaccatgg ttagttatcg gcggcgttgt
   109801 tagttccgta ctcttggtag caatctttac caatttcttt ggcttagcta ctcataatac
   109861 gactttattt atcatattat ttgcaatcgt tttcatctta ttggatagtt tttattcatt
   109921 taaggatatc gctttttggt caatgattcc agctttgagt acggaaacaa aggaacgtga
   109981 aaaatttgct acgtttgctc gtttcggctc ttctctaggt gcaaatggta ctactctagt
   110041 cgttgtccct atcgttactt tctttaccta tcttgttact cataaacata ttgaaggcgc
   110101 ttcaggctgg ttctggttcg gtgtgattgc tgctgttatt tcaggcggta ctgcgattat
   110161 cactgccttg ggcacaaaag aagtcgatac tgcgatccgt cagcaaaatg aaaaagctgg
   110221 gatcaaagat gtgttcaaag cagttgctca aaatgatcag ttgatgtggc ttgcccttgc
   110281 ttatatcgct tatgcgattg ccaatgcagc aacaactgcc gtattattct acttcttcaa
   110341 atatgtactt ggccaaccaa ctgaattttg gatcgttggt ctagttgctg ccttacttgg
   110401 tttagtagct gttccactat tcccaatgct tacacgcgtc atctctcgtc gctacgttta
   110461 ccttggaggg atcgcaatga tgatttcttc ttactttttc tttacgatcg caggttcaag
   110521 tttgccaatc gttatcatcg ggctagtatt gttctacttc cctcaacaat tgattttctt
   110581 atccgctttg atgacgatca cagactctgt tgaatatggt caatggaaaa atggtatccg
   110641 taacgaagct gttactctat caattcgccc tttactagat aaaatcgctg gtgctttgtc
   110701 taacgggatc gtagggtttg tcgctatcgc ttctgggatg actggtaatg ctactgctgc
   110761 tgatatcact gctcatggcg taacgacttt caaagcttat gcattctatg ctcctgctgc
   110821 tttgatgatt ttctccgcta ttatttttgc ttggaagatt acattgacag agaaaaaaca
   110881 tgcacaaatc gttgagaaat tggaaaacaa attggctcca gctgatacaa tggaagatta
   110941 acttcacgat gcagtagttc cttcccatta agaaaggatc ttgaaaatga agattacaga
   111001 aaaagatttt ggccaaggtt atcacttgat aaccttggag aacaaaaaca agctagcact
   111061 ttctatctct gatttaggtg ctagaatcgt cagtttaaaa tcaaatgatc gagaattagt
   111121 tttgggattt gacaccgctg aagaatatat cgaaaaagat ccgtatatcg gtgcttctat
   111181 cggtcgcacc gcagggagaa tcgaaaatgg ccgcttttct ctcaatggaa aaacttacca
   111241 attagccaca gatccaaaaa ctggacataa tctgcatggt ggtgctcctg gatttgaatt
   111301 aaaaaaatgg tcttatgtca ttttgaatgg cgaaaatgaa gcttctgtca tttttactac
   111361 tacaagtccc gacggagaac atggttttcc aggtacaatg gatgtggaaa tccgctatac
   111421 tttgacaaaa gataatatct ggcgagtgac ctctcgcggc accagtgacc aagatacttt
   111481 attcaatccg acaaatcatg tttacttcaa cttgacggga gatgcttctc agtcaatcga
   111541 tcaacatgag ctttggctca atagcgaagc ttatgctcct ttgcgaacag atagtattcc
   111601 tataggggta aaagaaaatg ctgcaggaag tgctttcgat tttcaaatac ctaaaaaatt
   111661 agcgtccgtt tttgctagtg atttggatca aaaaaatctt gttgacggaa tcgatcatcc
   111721 atttttctta aaagaaaccg gcttgggtaa agaagccgct cgcttgacta gccccgataa
   111781 aagaatccaa gtagatattg ctacagatgc ttctagtgtg gttattttca ctgcaaattt
   111841 cggcacagaa acaccagaaa tgcgcaaccg aaaactggca catcacggtg gcatcacatt
   111901 tgagactcaa acagctccag gtgcagagcg cttctcagca tttggttcga ttcatttaaa
   111961 agccggatca gtatttgaaa cagtaacaga attcaaaatc aaaacaagaa aggaataact
   112021 catcatggaa atcaaaagaa gcttaaacac aaaatttgcc gaaacattcg gacctaaaaa
   112081 aactacacaa tacttctcac caggacgcat caatttgatt ggtgaacaca cagattacaa
   112141 tggaggccat gtcttccccg cttccatcac ttatggaacg caaggtgtag cagcacctcg
   112201 agacgataat aaaatattag tttattccac aaactttgac gatatcggtg tcattagttt
   112261 tactttagat gagctagaat atgataaaaa agcaaactgg gcaaattacg taaaaggaat
   112321 ggtccttaaa ttaaaagaag ctggacactc aatcgatcat gggtttgagt tattagtgga
   112381 aggaacaatc cctaatggtg caggactttc cagtagcgct tcattagaat tattagtagg
   112441 tgttgtatta gaagatctgt ttgatttaaa aacagatcgc ttggaactag tccaaacagg
   112501 taaaaaagta gaaaatgaat tcatcggtgt caattcaggt atcatggatc agtttgccat
   112561 cggcttcggt gagctagatc atgcaatctt attagataca aatacgctga aatacgaaat
   112621 ggttccagtg aaactagatg gttatgcaat cgtcatcatg aatacgaata agcggcggga
   112681 attggcagat tcaaaataca atgaacgccg tagcgaatgc gaagaagcct tggcacgttt
   112741 gcaaaaaact ttgcctatct cttctttagg agacttagat gaagaagaat ttgaatcaac
   112801 tattgaccaa atcggcgatg atacattgat acgcagagct cgccatgccg tttctgaaaa
   112861 tcagcggact ttgaaggcaa aagctgaatt agaagctggg aacttagaag catttggtca
   112921 actgttaaat gattctcacc actctcttcg ctatgattat gaagtaactg ggatcgaatt
   112981 agatacacta gtagatgctg ctcaaaaaca agaaggtgtc ttaggtgcac gaatgacagg
   113041 agctggattt ggtggctgtg cgattgctct tgtcaaagaa gaaaatatac ctgccttcaa
   113101 aaacaatgtc tatgatgaat acatgaaagt tgtcggctat gctccggaat tttatgttgc
   113161 acacattgga aatgggacaa caaagatcga tccagaagct gttcatgttt gataaaaaaa
   113221 tcaacgatct cagctaaaaa caaatagata aaaataacct ctcagcaatt tccaaatgtg
   113281 agccttttgc tcgtatttga aaattgctgt tttttattga cacggaaaga gaacgtgtgt
   113341 tctaattgtg ttgaagaggt gattgttatg tgggcgaatc aaaatccggt atttgtttat
   113401 gaaaaagaac cttcaagaga tattttatgt attgactgca aatcttttta cgcctccgta
   113461 gagtgcgttg aaaaggatct tgatcccctt acaactaaat tagtagtcat gtcctatccg
   113521 tccgattcga cagaaacacg gggtagcgga ttaatcttgg cttccagtcc tgcagcaaaa
   113581 aaagcttacg gcatcaccaa tatcagccgt gccagagatc ttcccttccc ctatccaagt
   113641 gatttatata ttgttgcccc aaggatggcc tattatatgg aaaagaacag agaaatcaat
   113701 tctatctata aaaaatatgc agacgaagcg aaccatcatg tctattccgt cgatgaaagc
   113761 ttccttgatg taacaaatag catggcactc tttggtaaaa caaatgcgta cgacatggct
   113821 aaactgatcc ataaagatgt gtttgagcag accggaatct acacgactat aggaattggc
   113881 gataacccgc tacttgctaa actagcctta gacaatggct caaaagacgg aaagcaaatg
   113941 tttgctgaat ggcgttatga agatgtacca gaaaagttat ggaaaatctc agatatcact
   114001 gacttttggg gaatcggcaa acgaacagca aaacgtctga aacaaatggg tatacattct
   114061 gtttatgatt tagctcacgc ggattattat cacttgaaaa gcaagctagg ggtcatcggt
   114121 actcagcttt atgcccatgc ttggggcatc gatcgaagtt ttttgggaca agaatataca
   114181 ccaaaatcaa aaagtatcgg aaatagtcaa atcctagata gagattatac aagacgagaa
   114241 gaaatcgaga tcgttatcaa agaaatggcc gaccaagtcg gcactcgctt gagacgatct
   114301 gcagcaaaaa cacaagtagt cagcttatgg gtaggatact ctttaggcta tcttgatcca
   114361 aatggcaaga ccgggtttca ccagcaaatg aaaatcgaag cgacaaatgc tagcagagat
   114421 cttgcagatg ctttattgac cattttccac cagcattacc actaccagga tattcggcgt
   114481 gtaggcgtga actgttccga cctcgtatac gcgacaggtt tacagcttaa cctttttgaa
   114541 gatcctgaaa agcagataaa tgaagcgaaa gttgattttg ttgtcgatac gattagaaaa
   114601 aaatacggct ttcaatcaat catccatgcg catagtctct tgcaaggagg acgcgccatc
   114661 gcacgtagtt ctctcgttgg cgggcatgca ggtggtatga gtggattaga aggtggaaaa
   114721 gatgagacgg acagcaaaaa aattcattga ctataacgag tatcgagatc ggccatttgg
   114781 attaaaatgg gggactgctt ttgcgatgga agaactagtc aacggtatca aaaaaatgaa
   114841 gaagaagcac gcaaacagcc tcttcctaaa caacaaatga cattgcaaga aatcgatagt
   114901 atactgacag aagccttttt atctcgtaaa gcagtaatca ttcagctcaa tttaaaagat
   114961 gaatttggaa gactcttgga tgaggtcgaa gggcacttca ttggtgaagc ctatgaagat
   115021 tactttatga ttgaccatca gccgatattg tgggaagacg tacggtatat tgagttaaag
   115081 gaaacaaaaa aatggtttgt gacatgagag gttgtgacag aagtgatcaa cttcaaaaaa
   115141 taagaaagga tttttcgaaa attgcttctt aaatttttgt ggaattttgg cttatttttc
   115201 gaagaagcaa cttctggaac aacgtatatt agatatcaga ggttgtgaaa aagtcgctta
   115261 gttttgagta acaagccaag gcgctgattt cacaacctct gtctatctat ccatctattc
   115321 ggtaagattc atgcatgacg tcttctttat ttagtatgta gagccctttt tcttctgacc
   115381 attcaacata aatcagctgt tttacatctg catagccttc tttcttcaag ttctccataa
   115441 gccatgcttc agtcaattga ttggactgaa gcactttatg ctgaatttgc ccttcatcta
   115501 caagcaggat cgataaagct ttgtcttcat ctgatttttt caatacactc atttgaccgg
   115561 cattctctag gataacatgt ttggcatttt caagaaaaaa gcattcttgc tgtcttaaga
   115621 ttgctcgcaa ctgctccatc tcgatatggt tatttgtcaa ctctgtcatg ttgatgacgc
   115681 cgtctttgat tagaacagat ggctcgcctt tgacccaacg attgaccttt tcattttttt
   115741 ggacgatacg ttcgatacca taaatcatta ctgcccaaag cgcaatggca aataggacat
   115801 gccctacatg gacattgtca tcataggttg attcttctaa gatcccacct aaaacaagcg
   115861 tatagactaa atcaaacggt gtgatttctg acatggattt cttcccaagc aaacgtacca
   115921 ctaataataa accgatcaac ccgaacacca gtttcattgt aattgaaaaa atcatttttt
   115981 ctccccctaa ctatctgtta attaaattat atatgctttc tcacgaacac gcatggaata
   116041 tacaaggaag aaatgtatcc ttttactaaa aaaaggactg tgacactgta gtgaccccca
   116101 aaagttagac ttttttggag tggagaaatc cactcctttt ttttatgctc taaaatgata
   116161 tttttacaca accgttacgg ttgttttacg aaattggacg
//
LOCUS       DAMEEU010000002       100706 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.002, whole genome shotgun sequence.
ACCESSION   DAMEEU010000002 DAMEEU010000000
VERSION     DAMEEU010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 100706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 100706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..100706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.002"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(554..2167)
                     /locus_tag="PB779_000113"
     CDS             complement(554..2167)
                     /locus_tag="PB779_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDE0737668.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2308..3216)
                     /locus_tag="PB779_000114"
     CDS             complement(2308..3216)
                     /locus_tag="PB779_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0737669.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3399..4523
                     /locus_tag="PB779_000115"
     CDS             3399..4523
                     /locus_tag="PB779_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDE0737670.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4750..5667
                     /locus_tag="PB779_000116"
     CDS             4750..5667
                     /locus_tag="PB779_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0737671.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5660..6493
                     /locus_tag="PB779_000117"
     CDS             5660..6493
                     /locus_tag="PB779_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0737672.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6576..7694
                     /locus_tag="PB779_000118"
     CDS             6576..7694
                     /locus_tag="PB779_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDE0737673.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7688..9586
                     /locus_tag="PB779_000119"
     CDS             7688..9586
                     /locus_tag="PB779_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HDE0737674.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9580..10803
                     /locus_tag="PB779_000120"
     CDS             9580..10803
                     /locus_tag="PB779_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDE0737675.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10889..12823)
                     /locus_tag="PB779_000121"
     CDS             complement(10889..12823)
                     /locus_tag="PB779_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDE0737676.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13049..13705
                     /locus_tag="PB779_000122"
     CDS             13049..13705
                     /locus_tag="PB779_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDE0737677.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13779..14132)
                     /locus_tag="PB779_000123"
     CDS             complement(13779..14132)
                     /locus_tag="PB779_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDE0737678.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14324..15253
                     /locus_tag="PB779_000124"
     CDS             14324..15253
                     /locus_tag="PB779_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HDE0737679.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15264..16100
                     /locus_tag="PB779_000125"
     CDS             15264..16100
                     /locus_tag="PB779_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HDE0737680.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16348..17124
                     /locus_tag="PB779_000126"
     CDS             16348..17124
                     /locus_tag="PB779_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0737681.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17300..18043
                     /locus_tag="PB779_000127"
     CDS             17300..18043
                     /locus_tag="PB779_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0737682.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18036..19616
                     /locus_tag="PB779_000128"
     CDS             18036..19616
                     /locus_tag="PB779_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HDE0737683.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19867..20346)
                     /locus_tag="PB779_000129"
     CDS             complement(19867..20346)
                     /locus_tag="PB779_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDE0737684.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20362..21114)
                     /locus_tag="PB779_000130"
     CDS             complement(20362..21114)
                     /locus_tag="PB779_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HDE0737685.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21231..21301
                     /locus_tag="PB779_000131"
     tRNA            21231..21301
                     /locus_tag="PB779_000131"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21263..21265,aa:Gly,seq:ccc)
     gene            21662..22387
                     /locus_tag="PB779_000132"
     CDS             21662..22387
                     /locus_tag="PB779_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HDE0737686.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22642..22908
                     /locus_tag="PB779_000133"
     CDS             22642..22908
                     /locus_tag="PB779_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HDE0737687.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPSYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22905..23336
                     /gene="ruvX"
                     /locus_tag="PB779_000134"
     CDS             22905..23336
                     /gene="ruvX"
                     /locus_tag="PB779_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HDE0737688.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23361..23666
                     /locus_tag="PB779_000135"
     CDS             23361..23666
                     /locus_tag="PB779_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HDE0737689.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23747..24892)
                     /locus_tag="PB779_000136"
     CDS             complement(23747..24892)
                     /locus_tag="PB779_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0737690.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24953..25600)
                     /locus_tag="PB779_000137"
     CDS             complement(24953..25600)
                     /locus_tag="PB779_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0737691.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25794..26087
                     /locus_tag="PB779_000138"
     CDS             25794..26087
                     /locus_tag="PB779_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737692.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26131..26442
                     /locus_tag="PB779_000139"
     CDS             26131..26442
                     /locus_tag="PB779_000139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737693.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26439..27063
                     /locus_tag="PB779_000140"
                     /pseudo
     CDS             26439..27063
                     /locus_tag="PB779_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27204..27362
                     /locus_tag="PB779_000141"
     CDS             27204..27362
                     /locus_tag="PB779_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737694.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27363..27725
                     /locus_tag="PB779_000142"
     CDS             27363..27725
                     /locus_tag="PB779_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737695.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27762..28610
                     /locus_tag="PB779_000143"
     CDS             27762..28610
                     /locus_tag="PB779_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HDE0737696.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28600..30075
                     /locus_tag="PB779_000144"
     CDS             28600..30075
                     /locus_tag="PB779_000144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HDE0737697.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30341..30748
                     /locus_tag="PB779_000145"
     CDS             30341..30748
                     /locus_tag="PB779_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HDE0737698.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30751..30966
                     /locus_tag="PB779_000146"
     CDS             30751..30966
                     /locus_tag="PB779_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737699.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30970..31350
                     /locus_tag="PB779_000147"
     CDS             30970..31350
                     /locus_tag="PB779_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDE0737700.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31484..31639
                     /locus_tag="PB779_000148"
     CDS             31484..31639
                     /locus_tag="PB779_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HDE0737701.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31708..32181
                     /locus_tag="PB779_000149"
     CDS             31708..32181
                     /locus_tag="PB779_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HDE0737702.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32178..33872
                     /locus_tag="PB779_000150"
     CDS             32178..33872
                     /locus_tag="PB779_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDE0737703.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33838..34023
                     /locus_tag="PB779_000151"
     CDS             33838..34023
                     /locus_tag="PB779_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737704.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34027..35202
                     /locus_tag="PB779_000152"
     CDS             34027..35202
                     /locus_tag="PB779_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDE0737705.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35195..36718
                     /locus_tag="PB779_000153"
     CDS             35195..36718
                     /locus_tag="PB779_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDE0737706.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36774..37058
                     /locus_tag="PB779_000154"
     CDS             36774..37058
                     /locus_tag="PB779_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDE0737707.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37045..37380
                     /locus_tag="PB779_000155"
     CDS             37045..37380
                     /locus_tag="PB779_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDE0737708.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37675..38301
                     /locus_tag="PB779_000156"
     CDS             37675..38301
                     /locus_tag="PB779_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737709.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39043..39879
                     /locus_tag="PB779_000157"
     CDS             39043..39879
                     /locus_tag="PB779_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDE0737710.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39943..40374
                     /locus_tag="PB779_000158"
     CDS             39943..40374
                     /locus_tag="PB779_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0737711.1"
                     /translation="MLREMRLGDAEALREINAEQLGYDVPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKHAEKRGIGKALMTGVEEA
                     KRRGISAIRLNSAEYRVEAHRFYERIGYHSDKMQKRFLKIL"
     gene            complement(40436..41758)
                     /locus_tag="PB779_000159"
     CDS             complement(40436..41758)
                     /locus_tag="PB779_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HDE0737712.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFLDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRNVKPSIPQLGVGLMVSL
                     TFFILGQICNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41912..43552)
                     /locus_tag="PB779_000160"
     CDS             complement(41912..43552)
                     /locus_tag="PB779_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HDE0737713.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAATILEKYEDKITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQTILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     KGLTPGQIPFARKRSEFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQKLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43885..44355
                     /locus_tag="PB779_000161"
     CDS             43885..44355
                     /locus_tag="PB779_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HDE0737714.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLGANKAIISELTV
                     GGLVDSLALAEGFIGEDIYEMFSEIRQLKKGENCIEVHHESPNVRFKRGDNEMIFNNH
                     VSDHTELYGIVNQILTELFGLGPYAFKEENGNPKLNEEWQETIEIQRNNPHLFQ"
     gene            44577..45680
                     /locus_tag="PB779_000162"
     CDS             44577..45680
                     /locus_tag="PB779_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDE0737715.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHQLIIPHVLKDVELPDTTTHFDKETLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDDGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            45964..46644
                     /locus_tag="PB779_000163"
     CDS             45964..46644
                     /locus_tag="PB779_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDE0737716.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGPLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            46734..47768
                     /locus_tag="PB779_000164"
     CDS             46734..47768
                     /locus_tag="PB779_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDE0737717.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTVPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNAFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            47782..48117
                     /locus_tag="PB779_000165"
     CDS             47782..48117
                     /locus_tag="PB779_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737718.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPIPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEQKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48101..50581
                     /locus_tag="PB779_000166"
     CDS             48101..50581
                     /locus_tag="PB779_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737719.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLTDIIAIITRGEFNVDDIPLQFDVTANVAKMTENGDK
                     YDTSPNKILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGG
                     NLNPGAYAFSASAEINTWNSYISPSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLT
                     MGLTEGRFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQ
                     GGLLSPVALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIH
                     YRLYSKGTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTN
                     MYPSFAYKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQ
                     ENVTFTLTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLS
                     KIGDTIHLTYNYQLNTVDTSLQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTIL
                     VPKQELTLVNVPDDFTFGNDLPKPLKTSYYESKGDFSFDVRDTRLPSTSPWQLTGTLT
                     SLFKNDQGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLL
                     EVNSSTNAQPGATYQGMVTWKLTAGPTS"
     gene            50637..52196
                     /locus_tag="PB779_000167"
     CDS             50637..52196
                     /locus_tag="PB779_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0737720.1"
                     /translation="MRRKLLLLKSEMLEGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     VSVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQIRYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFAITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52193..53557
                     /locus_tag="PB779_000168"
     CDS             52193..53557
                     /locus_tag="PB779_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDE0737721.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQTIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEYTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            53728..54798
                     /locus_tag="PB779_000169"
     CDS             53728..54798
                     /locus_tag="PB779_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0737722.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAIGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            54813..55481
                     /locus_tag="PB779_000170"
     CDS             54813..55481
                     /locus_tag="PB779_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0737723.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEANELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55501..56079
                     /locus_tag="PB779_000171"
     CDS             55501..56079
                     /locus_tag="PB779_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0737724.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56480..57391
                     /locus_tag="PB779_000172"
     CDS             56480..57391
                     /locus_tag="PB779_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDE0737725.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(57479..58396)
                     /locus_tag="PB779_000173"
     CDS             complement(57479..58396)
                     /locus_tag="PB779_000173"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HDE0737726.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            58598..59035
                     /gene="zapA"
                     /locus_tag="PB779_000174"
     CDS             58598..59035
                     /gene="zapA"
                     /locus_tag="PB779_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HDE0737727.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59094..59642
                     /locus_tag="PB779_000175"
     CDS             59094..59642
                     /locus_tag="PB779_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HDE0737728.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            59757..62117
                     /locus_tag="PB779_000176"
     CDS             59757..62117
                     /locus_tag="PB779_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HDE0737729.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEEQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLYDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62204..62518
                     /gene="trxA"
                     /locus_tag="PB779_000177"
     CDS             62204..62518
                     /gene="trxA"
                     /locus_tag="PB779_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HDE0737730.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            62700..64478
                     /gene="uvrC"
                     /locus_tag="PB779_000178"
     CDS             62700..64478
                     /gene="uvrC"
                     /locus_tag="PB779_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HDE0737731.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKNFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELASKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGTDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            64623..65522
                     /locus_tag="PB779_000179"
     CDS             64623..65522
                     /locus_tag="PB779_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0737732.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            65515..66777
                     /locus_tag="PB779_000180"
     CDS             65515..66777
                     /locus_tag="PB779_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0737733.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWYSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            66938..68836
                     /locus_tag="PB779_000181"
     CDS             66938..68836
                     /locus_tag="PB779_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HDE0737734.1"
                     /translation="MDRYLDLLSEKFPSTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETDISQFTIFTAYPEYALTTDWYKEQDKS
                     QLIHHLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFAP
                     KNSKNLSEREQEELEKIHQALSILQFKSEHQLLDRRPEFKMDDRKLLEKIDYEASTID
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTAKEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDTKEEGSAIINGHTPVKVKKGESPIKANGKVFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRDTTKGMELQQQITQLKR
                     LLDYRKDD"
     gene            complement(69166..69885)
                     /locus_tag="PB779_000182"
     CDS             complement(69166..69885)
                     /locus_tag="PB779_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HDE0737735.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIGQIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFTTHEVKIVSD
                     SLLSNLLPDPYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDDMHKILGVQWHP
                     ELTHRVHPSEQRLFDFFVNEF"
     gene            70222..70554
                     /locus_tag="PB779_000183"
     CDS             70222..70554
                     /locus_tag="PB779_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737736.1"
                     /translation="MKQVLEALEQIRKAEEENEKRAQTLRQQLKIYATEKEQELETIQ
                     TNYRQQLKQLVEEKEQFEIQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            70541..72544
                     /locus_tag="PB779_000184"
     CDS             70541..72544
                     /locus_tag="PB779_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HDE0737737.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFINKLKEVLDLKEKWEQLTEERDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAVIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKIKERFIHATYLIVLQGWVDAEEKQNLLHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLVEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLLVLPRGMKRFVKFFEILSIPSIIWGLIYSSFFGQSLPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALVGAMLIKNTAFVYLGAGLSIIAALCILIVPIIQTPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            72563..73033
                     /locus_tag="PB779_000185"
     CDS             72563..73033
                     /locus_tag="PB779_000185"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HDE0737738.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73054..73638
                     /locus_tag="PB779_000186"
     CDS             73054..73638
                     /locus_tag="PB779_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HDE0737739.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQVETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAVTEMENWDESEQ
                     IQFIKNALYSLPLTGKVAFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            73653..74639
                     /locus_tag="PB779_000187"
     CDS             73653..74639
                     /locus_tag="PB779_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HDE0737740.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNIDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFESETIRKRVRQVYDA"
     gene            74629..74940
                     /locus_tag="PB779_000188"
     CDS             74629..74940
                     /locus_tag="PB779_000188"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HDE0737741.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            74962..76743
                     /locus_tag="PB779_000189"
     CDS             74962..76743
                     /locus_tag="PB779_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HDE0737742.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            76736..78112
                     /locus_tag="PB779_000190"
     CDS             76736..78112
                     /locus_tag="PB779_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HDE0737743.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78119..78754
                     /locus_tag="PB779_000191"
     CDS             78119..78754
                     /locus_tag="PB779_000191"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HDE0737744.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            78784..80139
                     /locus_tag="PB779_000192"
     CDS             78784..80139
                     /locus_tag="PB779_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk family potassium uptake protein"
                     /protein_id="HDE0737745.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKLAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKMTIHSKIALTVTGTLLLGGFVVFFFTERNGATLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80331..81725)
                     /locus_tag="PB779_000193"
     CDS             complement(80331..81725)
                     /locus_tag="PB779_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDE0737746.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQNLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQSKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRTQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            81817..82788
                     /locus_tag="PB779_000194"
     CDS             81817..82788
                     /locus_tag="PB779_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDE0737747.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKGKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSAALTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            82785..83567
                     /locus_tag="PB779_000195"
     CDS             82785..83567
                     /locus_tag="PB779_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="HDE0737748.1"
                     /translation="MNLDYYVVDAFADEVFKGNPAAVYVLEEWLPEGTMQKIAIENNL
                     SETAFTVKKNQEFELRWFTPDREIDLCGHATLATAFVLFNYYKIPDETIKFSTQSGNL
                     FVTRIKDYYYMDFPSIMPKKVPILSEYEEAIGAKIKEAYLARDLFFVLEDEKTVAKLQ
                     PDFTAIKNFELGIGVIVTAESVQKDFVSRTFFPKLTINEDPVCGSAHSNLIPYWAERM
                     NKTKLSAYQMSSRGGDLECELKEDRVIIGGKAVLFSKGTSFI"
     gene            complement(83736..84107)
                     /locus_tag="PB779_000196"
     CDS             complement(83736..84107)
                     /locus_tag="PB779_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDE0737749.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TAPSYYFVIDPDGYKIEVIRG"
     gene            84241..84684
                     /locus_tag="PB779_000197"
     CDS             84241..84684
                     /locus_tag="PB779_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HDE0737750.1"
                     /translation="MDKPIFGEKKQFADYQTRYAAYIVIERDQQIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(84727..85536)
                     /gene="yidA"
                     /locus_tag="PB779_000198"
     CDS             complement(84727..85536)
                     /gene="yidA"
                     /locus_tag="PB779_000198"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HDE0737751.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(85555..86922)
                     /locus_tag="PB779_000199"
     CDS             complement(85555..86922)
                     /locus_tag="PB779_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDE0737752.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHQVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(86906..87736)
                     /locus_tag="PB779_000200"
     CDS             complement(86906..87736)
                     /locus_tag="PB779_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HDE0737753.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            87899..88336
                     /locus_tag="PB779_000201"
     CDS             87899..88336
                     /locus_tag="PB779_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HDE0737754.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88412..89032
                     /locus_tag="PB779_000202"
     CDS             88412..89032
                     /locus_tag="PB779_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HDE0737755.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     GKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89221..89727
                     /locus_tag="PB779_000203"
     CDS             89221..89727
                     /locus_tag="PB779_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HDE0737756.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            89744..90643
                     /locus_tag="PB779_000204"
     CDS             89744..90643
                     /locus_tag="PB779_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HDE0737757.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKAKR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            90730..91614
                     /locus_tag="PB779_000205"
     CDS             90730..91614
                     /locus_tag="PB779_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDE0737758.1"
                     /translation="MKRNYLVISIIALSVLLFFEITSVASLITEVKGQTHSSEHSSQS
                     FKQSEQSTIKSQSTETANVKEAIQESAEKVQSQSSQSTQDSTKTSRDPAVKSVAISFD
                     DGPGATTTPQLLRILKEKNVHATFFVLGENTAQHPEIVKQTAEAGHEIGNHTYDHQNL
                     ATLSAQSMTEEVTKADTEIKKVTGKTPTFVRPPYGSVTNVGATIIQRPIIEWSVDSED
                     WKTRNPDLILQKIQATVYDGAIILFHDIYPETIRAVPQVIDYLKEQGYRITTVGDLLG
                     HPTAVENYYGRNDHRPVQ"
     gene            complement(91806..91877)
                     /locus_tag="PB779_000206"
     tRNA            complement(91806..91877)
                     /locus_tag="PB779_000206"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(91842..91844),aa:Arg,seq:ccg)
     gene            91937..93271
                     /gene="rpoN"
                     /locus_tag="PB779_000207"
     CDS             91937..93271
                     /gene="rpoN"
                     /locus_tag="PB779_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HDE0737759.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            93420..94511
                     /locus_tag="PB779_000208"
     CDS             93420..94511
                     /locus_tag="PB779_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HDE0737760.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            94552..95553
                     /gene="gap"
                     /locus_tag="PB779_000209"
     CDS             94552..95553
                     /gene="gap"
                     /locus_tag="PB779_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDE0737761.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            95663..96853
                     /locus_tag="PB779_000210"
     CDS             95663..96853
                     /locus_tag="PB779_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HDE0737762.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            96957..97712
                     /locus_tag="PB779_000211"
     CDS             96957..97712
                     /locus_tag="PB779_000211"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HDE0737763.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            97828..99126
                     /gene="eno"
                     /locus_tag="PB779_000212"
     CDS             97828..99126
                     /gene="eno"
                     /locus_tag="PB779_000212"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HDE0737764.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            99525..100664
                     /locus_tag="PB779_000213"
     CDS             99525..100664
                     /locus_tag="PB779_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HDE0737765.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
BASE COUNT        33405 a        17204 c        20783 g        29314 t
ORIGIN      
        1 tgttaaataa ataggaacaa aaaaattaaa ttatttaata cacacattag ggatcattca
       61 ttgaaggatt agaagacaac gaggatggcg aaaaatatga ttacaataga aaagtcgttc
      121 taaaccaatc agttcctagt atcacacaac gcaagccagt cgatttggtg agattagagg
      181 agtgaaagca aactttatta tataagaaaa aatattcgaa agggatgcta gtttaggtac
      241 tagtgctgat agattaatat gatgcctcgt aatattaggc gtagttactc tagagacatc
      301 actatggact atgatttgtc tcagagtcac aacatgtttt tttatgaaaa gaaacagcta
      361 aaataattaa attgcgcaat gtttaaactt tcttaaacta taacctaata aatgtgaaga
      421 aataatgcac aatttcttca catttatctt ctattctata tacataccaa ccaacaaccc
      481 tatatacttt ttcattttta ctcctcaagt aaaaataact cctagaccgc ggctacccac
      541 cgcggtcgtt tttttattct tcaatcaaaa tcgctttgat acccaaacct gccaagattc
      601 gggcagaagt ataagtattc aatcctcttc tgaaagtaat gtaaactttt ttatcttttg
      661 ggatttcatt gattcgatct cgtaactcat tcattggaat attttttgtt gccgagatac
      721 tgccagaagg tgctttatta ggttcacgta tatctaaaaa gaacgcttct ttcaaatcgt
      781 tttcgggtat atcacttgct ttgatcgttt ctacgatatt cgtcatttga ttgattgcga
      841 cataaccagc tatattcaac gggtcacggg tagtagaata cggtggagag taaggcaact
      901 ccaaatcagg caaatcaaag actgtcaagt ttccggtgat tgctacagaa agttctccca
      961 tccgtttatc gacacctttt tctccaaatg cttgtccacc taaaatacga ccgctatctg
     1021 catcaaaaat cagctttaga tttaatcttg tagcttctgg atagaaatag gcatggtcaa
     1081 agggagtgat aaaaacagtt ttataatttg ttatgcctga tgcttttaat tcatgttctg
     1141 tcattcccgc ataacttgct gtatgatcaa agatttttgc gacacctgca ccaatatatc
     1201 cgcgatagcg cataggcgta ccatttaaaa tatctgccag catatgtcct tgacgattgg
     1261 ccgcactgga aagcatactt tggatcggct gaccagtcac tacactagtc gtttcgataa
     1321 tatcgccaat cgcatagatg tccggcagat tggtttgtaa ctggtcatca acaatgatct
     1381 gacctgtatc tgataattgt atgccggttg ctttcaccac ttcattcttc ggagaaacac
     1441 caacagcaaa aattagcata tcagcagaaa ggacggagcc atctgataat actatttctc
     1501 gacctttatc acggatctca gtaactcttg tttctaaatg aacggctaat ccttctttca
     1561 gcaatttgtc ataaactaaa ttagcaattt ctggatcata agggaaagcg acttgtggca
     1621 attgatcgat taaagtcacg tctaagccgc gatgcttgaa attctcagct aattccagac
     1681 ccataacacc tgcaccaaga atgacgacat gttgtggatt tttttcttca aggaacgatt
     1741 tgattcgatc cgcatccgtc acactacgga ggacaaagcc gttttctgct tcaaaaactc
     1801 cgggaatatc cggataatct ggtctagcac cagaagagat gatcaactta tcgtaatctg
     1861 tttttatttc ttcatttgtg gataggtctt taactgttaa tcgcttagta gaaggatcga
     1921 ttgctgttac ttcgtgttta gtaaagacat cgatgttgtt ttttgttttc aatatttctg
     1981 gtgtacgttc gatcagcgag tcacggtcag tgatcacacc tcctaaataa taaggcaaag
     2041 cacaacttgc ataagaaata ttttctccgc gttcatagat aatgatttcg tgcgcttcat
     2101 tcaatcgacg gaaacgagtg gcaaatgaag gaccgccagc tacaccgcca atgacaacaa
     2161 ctttcataaa aacatctcct tttctacgtt gatcgtacta tgttatggta aaaaacagca
     2221 aataattgtg ccggaaaatt attgtttatt ttgaatagac agaaaatata gagaaataat
     2281 ttgtggataa aacctaaaaa tttttttcta ttttaaggat agataatact ttgaagggga
     2341 taaccctgta tattttttaa aagctgaaga aaaatgatgg atcgaatgaa atcctaatat
     2401 atctgcaatt tctgtatagg ttaattcatt ttctagcacg agacgttttg ctttttccat
     2461 ttttagttct ttaaaatagc taataacact ttttccattc acttttctaa aatgtttttt
     2521 taagctggct ggactgataa aaaaaatttg ggctaattgt tcaagcaaaa aattttctga
     2581 aagatgttct tctaaatatc gtatgattgg atcaactaat tcatctgaat aaagaatatg
     2641 ctttttttta ggaatgactt tctcatttga aggtattgtc aataaagcaa gttcctgttg
     2701 ataatgcctt ggtaaggaag acaattgaat tttttgcaga caataagtaa ctaataagga
     2761 aagcaaatga atgctcatct gttggcatag tatgaaaaaa gaattgattt cctgatcata
     2821 ggaaatagct ggcttactat gttttagata atcaattttg aactgttcat ttttcagaaa
     2881 agtaatgata gatgttattt cttgatctat agaaaaagat tgtcccgtaa tatgtgctaa
     2941 taattgctca tcaaaataaa actggataat gataaaagtt tgtgtttcct tttgagtaga
     3001 aaagatttgg acttcttgct gtttatcaat gaataaaagg gaaggattat ctagttctat
     3061 agatttatgt gcaaattcag catataaatt agcgctttca tttattagta gtcgaaaata
     3121 gggagcagca gataaatgaa gatgggtatc tatggaatag gttagtgttt ttttgacaag
     3181 attggaggat tggttgtttg ttaacaaaag aaccactttc ctttctcttt ttatataaaa
     3241 agctttctat ttataattaa tgactattat aacaaaaatg aaaagccaaa acgacaagta
     3301 aaatattttt ttatataaat atttgtgtta ctaattccgt taatatacat aagtgaaagc
     3361 gttttatata agaacttgaa aagaaagaag ggatagacat gaaaaaaaga tacaaattgg
     3421 tgatagcttt gctaaacatt accctattat tcagcttaag tgcatgtgga aaaactaacg
     3481 aagaagtaac agcaaacatc gcagatccaa tgataaaaaa agccactaca ttagaagtat
     3541 atgtcgcaaa cggcaaactg acaaactatg ttgaaaatgc tgcaaaaatc tataaccgca
     3601 aaactggagc aaatattgac ttaaaaattg tgaatgtagc ttcgggaaca gcaacagtac
     3661 aaatgatcac cccaaaattg gtaacacacg aagatatgcc ggatattatc tccatggcag
     3721 acacttcagc agcaggtgtg ctggaaaaat ttcaagatgc tttttatagt gctgatgaat
     3781 atggatttta tgacaaatat ggcgatcagt tttatgatca aaaattgaat attttgcgtc
     3841 aacaaacgag taatgaaacg attattcctt gggctagtga ttttacccca gcactttgtt
     3901 attatcaacc aaaaaaattt gctgaaatag gtgtagattt tgaagaaatc agttcttggg
     3961 aagaatatat ccaggtggca aaagcattaa aagaaaaaac tggtagtttt ggaattgcct
     4021 tgccagaatc tggggaccaa gaattgttta tcaacatgct agcccagcag aatcaatctt
     4081 tgcttgatga agaaggaaat atccgtctga atactaaaga agcgaaacat gctgcaaagt
     4141 taatcaaaga aatgatcgac tcagatattg tacatttcta cggtgcacaa gatgctgaga
     4201 aagcatttca agaatctgca atgtttgttg ctggcggctg gtatgctacg aatatgtctt
     4261 tgaattttcc tgatgcatct gacaaatggc gcatggctcc actgattcct ttttcaaaag
     4321 aaaatccagg aaaaggtgca gtatcaggag gatcaagttt ttatgtccct aaagatgcaa
     4381 aaaatccaca agtggcacaa caatttctta catttatgct gacagatgaa gaatgcttag
     4441 ccaacgcact ggagctgggc gtggctacat ctaactcatt ggcctatcaa acagaagcag
     4501 ctgagaaaaa gtttgactac taaggaggac aaaaatacta tgaactattg aataaaatca
     4561 atgaaaatac atcaaatact gttttaccag ccacttattc agatgctacg tcttatttga
     4621 ctaccgctgc atataactat tggcaaacag gtgattttga aaattcatat ctaaaagaag
     4681 cagaaaattt tgctcataag tacggcgtaa aattaactgg tgattaaaaa atattaggag
     4741 gacttaacga tgatgcaatc ttcgttacca agcaagacaa taaagaacag caagaaaaaa
     4801 gcaacagata cgtctcataa aaaaagtgct tatggattgg tcacaccttt tgttattttc
     4861 tttattgtga cgattttgat tcccatcatt atctcgtttg cttttagttt tatgaaaatt
     4921 ggctactcat ttgaatttgt tggatttgac aattatctag ctatcttccg agatccattg
     4981 tttattaaat cttacacgaa tgttttgatt atcatggcag gatcaattcc aataacgatg
     5041 ctattagcta tttactttgc tgttttattg aattcagcac agttaaaagg aaaaggattt
     5101 tttagaactg tctattatat tccaaccatt acatcaacgg tggctgtagc ttccgtattc
     5161 atgacttttt tcaatccgac tgggttattc aatggatttt tgaatgcgct aggaattaac
     5221 ggtgtacagt ggttaacaaa tcctttttgg atacgaatat caatgatcat cacgatgatt
     5281 tggcttagtg taggatataa cactatttta tttttagctg gtcttcaagg gatttctaaa
     5341 gagatatacg aaagtgctga aatagatgga gcatcgaaat ttcggcaatt ctttttatta
     5401 acgatcccca tgctaaagcc aatcatttta atggccacag ttttagccac tatcaatggc
     5461 ttgggtaatt tcaatatccc aaatatattc tttgggactt ccaatggacc agaaaattca
     5521 gctttggtcg taggagtcaa tttatataaa acaagttttg aaatggttga ttttggaaaa
     5581 gcctctgcta ttgcctggac gatggtgttt gtatctgtta tattatcggc tattcaattt
     5641 aaattcggag gtgataaaaa tgactaaaca aaagatacaa agcagaattt ttacgtacgt
     5701 cattattgtg tttggtgcct taatattttt gatgccatat ttatatatga ttgtagcttc
     5761 aacgcaaagt aatcaagaaa ttttaagtgg cggaatcaat ttcaagtttg gggatatgct
     5821 attaaaaaac tggcaagcca tcatggcgag atataattat cccttgatta tttggaattc
     5881 gattgttatt gctgtaatca gtacagtttt agctacagcc agttctacaa tggcgggtta
     5941 tgcattagca aagtatcgtt ttatggggaa taaactgttg ttcaatacag ttatgctatc
     6001 taggatggtg ccttttttta ccacattgat tcctttattt tacattatga gtcgtttagg
     6061 attatcgaat acttatgcag gtgtgatcat cccttcgatt gccagtacaa cttcagtgtt
     6121 tatgatgcga caatatagca gtcaatttcc tacagcactg atggaggctg ccagaatcga
     6181 tggtgccaat gagtgggtga tttttacgaa aatcgctgta ccgattttat cacctacgat
     6241 tattactagt ggtttactta tctttatggg aagttggaat caatatctat ttccattagt
     6301 catgctttca gataaagata aatatacggt tcccttaatt atcaaaaata tgacggtttc
     6361 tagtacaggt gagccaatta attatggcgc aattatgcta attttagcaa cttcagtgat
     6421 cccaatggtc ttgatttatg tgtgggcgca gtctaaattt aaggagaatg acattggagc
     6481 tgcaaataag taaaaaaaat aacgaatgtt aaccatctag ttcgttctag gagcaactcc
     6541 acattcataa aaattaaaag aatggcggga tatccatgaa tgaacagacg aaggaatggt
     6601 caagaaaaat tttgaatgta gcttctgaaa agatagatgc ggaattagac agaatgggga
     6661 ataaaattcc atatatttct tacaacggaa aatatacaga cgtaataaag gacagaggaa
     6721 tcgactggtg gaccaatggt ttttggagtg gtattttatg gcagctcttt cacaagacaa
     6781 aacgagaaaa gttcaaagag gcagcaatac aacaagaaca attattagaa tctgccctgt
     6841 accatttttc agacgttcat catgatgtag gttttttatt cttaccatcg gctattgcac
     6901 attatcaaca gtctcaaaac aaacatagtc gacaactagg gttacatgca gctacggtac
     6961 ttgctggacg ctataatatt tcagggaact atttagtagc atggaatgac cataaacctg
     7021 gttggatgat tattgatagt atgatgaatt taccattact gtattgggct tcgagggaaa
     7081 ctggtgatcc gaggttctct aaaattgctc ggcagcatgc agatacaaca gctaagtatc
     7141 tagtgaggaa agatggatca accgggcata tcgcagaatt tgatgcagaa tcagggaaat
     7201 atattcggtt acttggcggg caaggataca atgagaattc ttgttggagc agaggaaatg
     7261 catgggcttt atatggattc gcgttaagtt atcgttacac aaaaaatccg tactatctag
     7321 ctatagcaga aaagatagca gtaaatttta ttcagaaaat cgaaaaaact ggttatattc
     7381 ctctcattga ttttgctgta aaagattcga atattgatac cagtgctgga gtatgcgctg
     7441 catgcggtct tctggaatta gcaggatatg tttcctctgt acgatcaaaa atgtatcatg
     7501 aagctgctat caatatactc caaaagacag aaaagcacta tgcaaattgg aatatggatg
     7561 aagatgggat cattggaggc ggagcagaag cataccatag agaactgact tataatgtgc
     7621 cactgatcta ttctgattat ttttttattg aaggcttact tcgattagaa cagtcggaat
     7681 tagctatttg gtagtaaaaa gaggagaaaa tacaatgaaa catccagtac cactattaag
     7741 gaccagacag gattactttg acttatttaa aaagataaat caaccactcc agccgtttta
     7801 tcgagcaagt ggcgcacaaa ttgattatat acatcaaggg gtaggatatg gaaataaaat
     7861 tgcaggaatg gaaggattct ctcgggtttt atggggagcg gggcccgcaa ttgaccaatt
     7921 agatgaacga tggttgaaat taattctatc aggaataaaa gctggaacag atccttccca
     7981 tcccgattat tggggagaaa tacatgaaag agaccagcgt atggtagaaa tgcccgcaat
     8041 gttattagcg ttatatcatc atgaacaatt attatggaaa aaattagata caggagaaaa
     8101 aagccagatt attcattggt tctcgcaaat ttttgaatat gaatgtgcag atggtaattg
     8161 gcaatttttt aagataattg tcggaacaat tatccaaaaa tttggttatc cagttaaaga
     8221 atcagcactg aaagaagcat ttgataatat agaaaattgt tatcttcaaa atggctggta
     8281 tcgagacagt tcaagaggtc gccaagatta ttataatcct tttgcatttc attattatgg
     8341 tttgatttat agcgtactag aaccagaaaa gcccattagc cagatatata agaaccgagc
     8401 tattgatttt tctagagact atattcattt ttttgcggaa gatggtgcaa atgtgccttt
     8461 tggtcgaagc atgatttatc gttttgcagt ttcaagcttt tggtcagcta tgttgtgggc
     8521 cgatcttttg ccttttaaat taggtgaaat caaggggtta gtcaatcgga atataagatg
     8581 gtggatgcaa aaagaaatat ttgatgaaaa aggtatcctg aatattggtt atacctaccc
     8641 tcaattgaca ttgactgaac cctataatag tacgttatct ccattatggc tgaataagat
     8701 ttttttattg ttggcgctac ctgaagacca tgagtattgg acggctaaag aaatgcctat
     8761 gcctattcgt gaaggaacta aacttctttc agaagccaat ttgctcatac aacatgataa
     8821 tggacataca ttttttttga atgcgggaca attagggcca aatttccata cattgaccaa
     8881 tgaaaaatat ttaaaatttg cttattctag tcaatttggt ttttcgatac cgcgagcgaa
     8941 tcaattgaaa gcagaaatgg caatggattc aatgctaggg attcagcgag cggacacata
     9001 tatcacgacc agttttaaga atgagagcat caaaacctat ggacagttca tcgttcgaaa
     9061 taatgtacga gacattgtat gtaagaaaga ggtacttgcc tctacatggg aacctacttt
     9121 acaggcaaaa atcagaactt ggcttattcc ttttgaaggc tggcagattc gcgtacacaa
     9181 agtagaatta gatacagaat atgttctata tgagacaggg tttgctattg aatgttctcc
     9241 tgagaaagaa ggaataatca tagaagaaga caaggaaaac tatagggtga gtgaagctgg
     9301 cttttcaggt attatctgtt taagtgacga tactattaaa cgaaaatcca cagctattat
     9361 gggtttgccc aatacaaact tgatgacatg ggaaaacact tttattcctg gattagaggg
     9421 tacatttgga aaaggaaccc attggctcgg aacaggagtg gttgctcatc aagatcggga
     9481 ttatagttta gaagtatgga acaatcgtcc caaaattgat tttgatggga caaccgggct
     9541 aactatccaa aataaaaaca ataaaaaaag actaaaatta tgctaaaggc tggtggggaa
     9601 atgcttgata aagtgatgtt tgaagagata atacatccag aaaaatggat aaatgaatgt
     9661 tataaagaat taatggaaaa agaatggaat aatgagatcg agcgttgtcg cagacacacg
     9721 gagaggttaa tcaaacgtat cagtaacagt cagtatcaat tcccaagcga gtgtcctata
     9781 aaaggacgtt atccattaag agacaatatt ggttggacag aaggattttg gacaggaatt
     9841 aattggttgt tatttgagaa gacgggtgat cctttatttc aacaaacagc tgaaaaagca
     9901 gatatagatt ttatccacag gattgactgt caaattatca ctaatcatca cgatcttggt
     9961 tttttgtatt ctttatcaac cgtagcagat tataaaataa cgggaaatcg aaaaatgaag
    10021 gaagcttcaa ttgatgctgc agaaacatta cttcagcgtt tttgggagaa ggcaggagtt
    10081 atacaagctt ggggagatcc tagtgatcct tcacaacaag gtagaatgat catggattgt
    10141 tgcatgaatc ttccattatt gtattgggcg agtgaagaaa ctggaaatca aaaatataaa
    10201 aaagctgctc aggctcatat tcaaaatgca gcagattatt tagtaagaga agatggttca
    10261 acttatcata cattttatat ggatgtcaaa gatggaaaac caagatatgg aagtacgcat
    10321 caaggttata gtgataattc ctgttgggct agaggccaag catgggggat ttacggtttt
    10381 gcattaagtt atcgttattt gaaagaacaa aaatattttg atttaagcaa aatattagcc
    10441 aattatttta tgaatcggtt gccagaagat accatttgtt attgggattt gatctttgat
    10501 gattctagca gagaagaaaa agatacatct agtatggtga tcatggtttg tggattatta
    10561 gaattaatag aatcaggtct attagacaaa acagaaaaga acttatacca gtctgctgtt
    10621 tggaaaatta tgcgacaatt gaaagaaaga tatgctacaa cggaagaaga agatggcttt
    10681 ttaacacagt ctgtttataa taagcccaaa aataatgggg taaatacacc ttgtatttgg
    10741 ggtgattact attatttaga agctttagtg agaatgacta gtaattggtc ttcttattgg
    10801 tgaaaaaggt aaatatggaa tttttgtttg ataaaataaa aaaagaaaaa ccaaaacagc
    10861 atgaatggtt tctgttttgg ttttttcgtt aattttcata ttcttctaat tccaagctta
    10921 gttcttccca ttccgtcaat tttgtttctt gatcttgtct agcagcttct aaatcttggt
    10981 tcagctcatt gagttttacg tgatcttcca ggttttctgg cgcgaccatt tcttgttcca
    11041 actgatcgat ccattcatcg atccgcgcca tttcttcttc aacctgagta atttttcgtt
    11101 gaaggctacg gataagcttt tgctgttctt tgctttggta ataatcagat ttgttcgtgg
    11161 gagcaggagc agattctggc tcatcttgtg ccaacaattc ggcgatttct tcttcttcct
    11221 gctttttctc taaataataa tcatagtctc ctagatagac tttgctgcca ttttcagaga
    11281 gttcgacgac ttttgtcgcg atccgattga tgaaatatcg gtcatgggaa acaaaaagca
    11341 gtgtgccgtc ataatcgatc aatgcatttt ctaatacttc tttgttgtca atatctaaat
    11401 ggtttgttgg ttcatccaaa atcaaaaaat tttctttgtt catcgctaac ttggctaaag
    11461 caacccgtgc tttttcaccg ccacttagca gagggattgg tttttctaca tcttcgccag
    11521 aaaataagaa agcacctaaa gcacttcgga tctctttttc tggagtggta ggatgctcat
    11581 cccacaattc tgctaggatc gtcttgtttg tatgcagatc agcttgacct tgatcgtaat
    11641 agccgatggt gacatttgtc cctagcgttt cttttccacg gataaaaggg atctggtgaa
    11701 tgattgattt cagcaacgtc gatttcccga taccattcgg acctactaga gcaatcgctt
    11761 cttgacgacg gatatctaga ttgattggtt cagataaggt gacattatca tatccgatag
    11821 cggcatcttc gatttgcaag actacatttc cagaaggctt ttctatactg aatagaaagt
    11881 ttgcttgttt ttcatcccct tgaggacgat ccagccggtc cattttttct aatgtctttc
    11941 tgcggctttg cgctcgtttt gtggtagagg cgcgaacaag gttccgagca acgaagtctt
    12001 ctaatttatg gatttctgtt tgctgctttt cataagcctt ccattcactt gctaactgtt
    12061 ctgctttcaa atctagatat ttcgaatagt tacctttgta atggcgcatt tttcttctgc
    12121 ttaattcata gacttcattg actactttat ctaaaaaata acggtcatgg gaaacaatca
    12181 ataatgcacc agtatagctt tgcagataat tctcaagcca ggaaagtgtc tcgatatcta
    12241 aatggttcgt tggttcatct agaatcaaaa tgtcagggtg ttgcaaaagc atgcgagcta
    12301 aagctaaacg tgtgcgctgt ccgcctgata aagtatcgat tttctgatca taaaatgaag
    12361 aatcgaattt aaacccatgc aatacggaac gaatttcatt ttcataacca tagccgtttc
    12421 gatctgaaaa atcgtgttgc agccggtcgt attcttttaa ataagaacta taagcaggtg
    12481 tgtctggcgt accttcgcta atgaaaatct ctagctcgcg catccgctct tccatttgtc
    12541 taacttgttc aaaagctttc agcatctcgt tccaaactgt ttcattggaa tcaagtcctg
    12601 tgtcctgagc gaggtatccg agagtcgctg ttttattttt agcgatcttt ccttcatcag
    12661 gtgcttcaat tccagcaatg atctttaata aagtcgattt tccagcgcca tttctgccaa
    12721 ctaaagcgac acgagcgcct gtactgattt ctaaatgtat gttttcaaat aagacttctg
    12781 caccaaaatg gcgagcaatc tgattggctt gtaataatat catggaatcc tcttttctac
    12841 tttgtgaatt ctcctcaaat aaaaaactat ttttcaatta gtagtctacc ataaattcca
    12901 ttatactgcg agatttgcag aaatgataaa taaatgaata aagaataaaa tttcacaata
    12961 tctgagcaat ggaattgatt ttttcctata aatactgcta tgatggagaa atcaaagatg
    13021 taattagaca atacgtggag gtcatttcgt gaaagatcat attattccaa aggcgacagc
    13081 taaaagactg cctttgtatt atcgctattt aaggatttta aataatgctg gaaagaaaaa
    13141 agtgtcttca actgaattaa gtgaagccgt tcaagtagat agtgcaacga tccgtcgaga
    13201 tttttcttat tttggcgaat taggaaaacg tgggtatggt tatgatgtag aagatcttat
    13261 gcactttttt gcaaagacat taaacgacga tcaattgaca aatgttgcgc tgatcggtgt
    13321 agggaacttg ggaagtgctt tactaaaata caaattccat caaagtaata gcatacgtat
    13381 cagttgtgct tttgatgtga atgaggaaat cgttgggcgc atcgtagacg gtatccccgt
    13441 ttatccaatg gaagatatgt cagaacaaat caagatccaa caaatcgaag tagcaatttt
    13501 aacgataccc gctgaaagag cacaagaagt agtcaatcag ttaacggaag caggaatcaa
    13561 aggaatcttg aactttaccg ctgctcgatt gaatgctccg tcagatgtat tgatccaaaa
    13621 tgttgatttg acgaatgaat tgcaaacctt gatctatttc ttgcattctg acgcaaatgc
    13681 gcattccgaa aatacagcag aataaaaata aaaagcgatt gaacaaatga aggcaaaact
    13741 ttcacttgtt caatcgcttt tttctgtttg gacaacgatt attttgttcg gaagatttct
    13801 tcataagaaa gggaatcatc ttctgctgtc agttcatcta gtagataacg gattttttta
    13861 aagtcgatga accgtgcttg ccgaaagact tcttttcctt gatgaaaaat caggacaact
    13921 ggcgcagtca gcacttcaaa tttactagct acttctggtg tttcaaatgc atccaaatga
    13981 agtgccggaa tatcataatg tgtgagaagt tcctctagtc gtggacgaac agcgtgacaa
    14041 acactgcaat taggcatcga aagataaatg acggcaacgg atgactgttg cagtatgtct
    14101 tgaacttcag tcaagttagt ggtttgtttc atttttattc tcccttttat gatagaagtg
    14161 atatgtatga gaccttaatt taatgggaat aacagaaaaa gtcaattgaa gtgctttggt
    14221 aaaaaataag agttgtgtaa aaatttacag agcaacttgt tttttttgaa taaaagcgta
    14281 tatttgcaaa gcgaatgaac tagaaataaa aaggaggaaa ctcatgtttt cttttattcc
    14341 aaattcggtt ttgcagatga gtacgatttt cttatcgatc gttattgaag cattaccttt
    14401 cgtattatta ggctgtctta tctcaggcgc cttacaagta tttttgaccc cagaacgtgt
    14461 gaagagatgg cttcctgaaa atcgtatctt ctctattttt actggttcga tcttaggatt
    14521 tttctttcct tcatgtgaat gcggcatcgt accgatcgtt catcaatttg ttaaaaaagg
    14581 cgtaccagtt cacacagcgt ttgcttttat gctgactgct ccgatcatca atccaatcgt
    14641 gattttttcc acttttatcg catttggcaa ttcttggcag atggcaagct ggcgggtgat
    14701 aggcagcttt tttgttgccc ttgtgattgg tgtctggctt gcctattttc aaaaagacgc
    14761 tgtattgaaa gaaaaaatca cgtctaaagt agcagaaaat caccatcatc atgtccatga
    14821 agaagaacaa agtgagaaga atgaaccaaa aaatcagctg atccatcaaa ctgggcatgt
    14881 gttgacacat tcaatcgacg aattttttga tacaggtcgt tatttgatca ttggcggatt
    14941 aatcgcagct gcgatgcaga cttatttacc aactagaatt atgctaacgc tcggctcaac
    15001 aaagatttta gccattatca tcatgctgtt attggccttt acgatgtctc tttgctcaga
    15061 agcagatgcg tttataggat cttctttgtt aagtctgttc ggcacagcac ctgtagctgc
    15121 ctttttggtc tttggcccaa tggtcgatat caaaaatcta ctgatgatga aacgatattt
    15181 tacaggacgc tttattttat cgctgatcgg actgattgcc cttagcgtta ttggattcac
    15241 attatttatt taggagggaa aatatgctgc ggtttttgat tttatctggg tatttcgaat
    15301 tgatgatgta cttgcaagtt tctggcaaac tcgatcaata tatcaatgtc cattatcgct
    15361 acttagctat tctttcaatg attttatctg ctcttttggc tttagttcag ctgtatttgt
    15421 gggtcaaaaa cggaaaagca gaagaaaagg cacacgagca cgatcatgac catgggttgt
    15481 caaaacctta tcaacgtgga atcgcttatg tactgctagc tttgccagta atcgtgggga
    15541 cgttgtttcc aacagttagt ctcgacacta cgatcgtaga agccaaagga tttaatttcc
    15601 cagtaagtaa agaatcagta ggggatccgg agatgcagac acaatactta aagccggata
    15661 ccagtattta tttcaacaaa tcagactact tagaccaaat gaatgagttg aaagaaaagt
    15721 atggggataa gcaaactatc aagatcacag atgaaaacta tttagaagtt atggagctaa
    15781 tttataatta ccctagcgaa ttcattggca aaaaaatcag ctatgaagga tttgtttacc
    15841 aaacaccgaa cgatagcaat acagatatct tcttgttccg attcggcatt atccattgtg
    15901 tggcagattc aggagtcttt ggtttgttga cgcatatgcc ggaaggagta acggttaaaa
    15961 atgatgaatg gtataaaata gaaggaacca tccaatcaga ctattatcaa ccattcaagc
    16021 gtgaaatccc atctgtagtt gttacaaacg ctgagaaagt ctctgctccg aaaaatcagt
    16081 atgtgtatcg ttctttttaa aagaacaaaa taaataaaca tagctcagac agctgacacg
    16141 caaggacgtc ggttgtctgg ctttttttgc atgatgtatt catttgtttg atatttattt
    16201 tagaagcagc atcctgaaag tatttgatat cggtttcaaa ggtgttggaa aagattgtga
    16261 agagaattac aatttattcc taacatgtat gttgaaaagt tgtatgaaat gattttgata
    16321 gtaaaatatc gagtggaggt actttttatg gtaacgcgta tatttatttt ggatgatagt
    16381 ttggtttttg aaaaaatgct agtagaaatt ttggaagaat ccagaatttt attaagtcct
    16441 tggaaatttg agatcgttca gggattgaac gttatacaat ttgttgaatt cattaaaaat
    16501 aatgaaatct attcctcaga tatttttttc ctagacatcg atttgaacgc ctattatagc
    16561 ggtatcgaac taggcgaaat gcttagagaa aagaatgaaa agtgtaaaat tgtttatcta
    16621 acgtctcatc cgaataaagc aataactgtt attaatcgaa agattacgcc tagtggttat
    16681 ttgataaaag aattcactta tgaaaaaaat aaaaaaagca tccaaagtta cttattgaaa
    16741 gaaaaagaaa actatcctgt tcaacatgct acgaaaaaaa ggtggacaac tgtccgttat
    16801 ggtaatagcg atcactatat ccattacgat gaaatccttt atctaatgag catgccaggt
    16861 tataaaaata aaataggcct agtattgaaa gatgaagaga ttctcgtaaa cggcacaatt
    16921 aaaaaatata aaaaatcact cgaatatgag tatttatgta aagatttaaa agcttatatc
    16981 attaatactg aaaacattac atctattagc agagtaaacg aaatagtaac atttgcaaat
    17041 ggagaacaac tagagatggg aaagagaagt attgataaac taaagaattt tatgcaagaa
    17101 aagatagaaa atgaatcatt ttaaagaaaa caaagactca tatcttacct gttagaagag
    17161 tgttttcctg tagaagagaa caacccaagt agcagcctag tcgtttctat ccttttttgt
    17221 tatgcactct ttttgacatt tactccacca ataacgaagg gtacaataaa aagtaataac
    17281 aaacaaaagg agtacagaaa tgattgaatt catcaatgta agtaaaagtt acgggaaaaa
    17341 acaagcatta aaagacttgt ctctctcgat aagacaaggg gaaatttttg gatttttagg
    17401 acataatggt gccggaaaat caactacgat taaaagttta gttagtatta ttgaaccatc
    17461 atcgggaacg attttagtag atggaatgaa attgacggaa aatcgattga gtatcaaaca
    17521 aaaaatcggt tatgtgcctg attccccaga tattttttta caattgacgg ctggagaata
    17581 ttgggacttg atttcagctg cctatgaatt agacacacaa aaaaaagaaa agcgtttagc
    17641 agaattgaca gcgctttttg atatgtatag tcatcaaaat gaaacaatcg caagtttttc
    17701 acatggaatg cgtcaaaaaa cgattttgat cggcacgttg ctgccagatc cagatatttg
    17761 ggtattggat gaacctttgc aaggacttga tcctcaagca gcatttgatt tgaaagaaat
    17821 gatgaaggct catgccgcaa aaggaaaaac agtcattttt tctacacatg tattggatac
    17881 cgcacaacag ttatgcgata aactggctat tttgaagaaa ggtgaattga tttatcaggg
    17941 ggcagttagt gaattattga atggctcacc tgatgaaacg ctagaaaaga tttatttgaa
    18001 aatggctgga aggcaagcga caggagatgg accgtatgta taagcgacaa ttattagaat
    18061 taattcgagt taatctttta tatgttaatc cacagctcac gaataaagca agagagaaag
    18121 gaaaaaaggg aaagcgatta actatctatc ttttgtctca aaatcttttt tcagggctga
    18181 tttttttact gatttacgga tttgctatgt ttgctatgaa ctttgttaaa ttgccaggtt
    18241 tctttactta ttacgtggca ctttttggta tgttaggttt aactcaaagt atatcagtca
    18301 tttataatat cttttttgaa ggaaatgacc tgcaagtatt tttgcctctg ccttttggac
    18361 aagaacaggt tttttcagca aagattttgg tagttgcttt gaccatcatt ccttttgttt
    18421 ttccgcttct agtcatgttt attttaaccg gatggcgagc tgatctaggg attttgctta
    18481 ctatcattat ctcaatcctt ttgttttctc tatttttgat tattcttttt tgtctggcta
    18541 gtttgattgt ttttggtttg gctcgaacag cagtgtttaa aaaacataga aaaacagttt
    18601 ctagtatctt gcttggcagc tcgatgctga tcgcatttgc tggaatcatg tggatgaatc
    18661 atcaaacggg gactattgaa aatgagttaa cagatcggca tccgatttcg atattattgc
    18721 cattctatga tgctgccagt cagccacttt ctcaacaagg tttattgggt tggggaatac
    18781 tagctatcac ggctctggga tttttccttg ctgtaaaaca gctgatagta ccaaagctta
    18841 cagagcaact gactgattca aacagtgagt tcaaaataaa aagaacccat aaaaagaacc
    18901 aaaatgtgca tcagctttta tttagttaca atgctcaatt agtaaaagaa cctaatttga
    18961 ttatgcaagt tctttcttct tccttgttaa ctccaatcat ttttattctt gcttttgccc
    19021 taggaggcga aataaaatta actgatttag ataataagtt aatcggtgtt gttttcctgg
    19081 tagggatcgc attggctttc ttaacagtta atcagacttc ttttatcagc aatcttattt
    19141 ctttggatca agaaaatttt ctgtttatcc gttctttgcc aatctctatg aaccaatatt
    19201 taaaagaaaa gttcagattc ggatggatat tgcagagttt tttaactggt gggatcgcat
    19261 tattaagcgg actgtctttt cagctgcctt tgttttttat ccctagcttg ctatttggtt
    19321 ctttattcgg ctgctactta ttgtcactac gttatttcgc tagagattat cggttgctgc
    19381 tgctgaactg gaccaatatt aaccaattat ttaacagagg ttcaggaagt ttgggtttag
    19441 tcgcaactat gatgggttca ttgatcatca gtattattct tatcgtctta tacggaatgt
    19501 tggctttgtt ttatccattt tggttagtga atattcctgt gatcggttta gttctaatac
    19561 tttccgctct atggatcgtt tattatcaac gaacgttttg gaaaaaattt gaataaagaa
    19621 gaggggccgt gacaaaaatc atgtcgcagc ccctttttta cagatagagg gtgttcaaaa
    19681 gtcagtttct cagtattaag tcaattttat gtaaaaatgt gagaagctat ttttacaaaa
    19741 ctttttttaa tactcataat tacttcttat tgctcctgcg gttacttgtc gcaatgtttg
    19801 tgagatattt tgtcatcgct caaggctgaa cgtctctttc acaacctttt ctttgttaca
    19861 cttcgtttat ttaaaaagcc gtttttttcg tttcatcatg attgcgtcac gctttacttt
    19921 gaaattacgg atgttatggt taaagacttc tgataataca agacctaaag cgattgctcc
    19981 agcaatcata attgcttgga ccgcataatg agccgcttct cgataggatt cagtaacgag
    20041 atttcgaacc gcttgataag ctaaaccacc agggactaga ggaaccatcc cgggaatatt
    20101 gaaaatcgtt acgggcattt tcaaacgttt agagaaaaga tcgctgatga atgctactcc
    20161 taaagaacca agcaatgaac caaaagcagc agatccgcct atttgaacac agatccagta
    20221 gatcatccag ccaaaagcac cagaaagacc acaacaaatc aatgaacgcc taggtacatt
    20281 tgtaataacg gcaaatgccg cagtcgctaa aaaactaaaa gaaaactgaa taaatatcgt
    20341 ccccatactt gtgttccttt cctaataaaa aagctggaaa ataaaagcaa tcgcaaaacc
    20401 gatcatcgta gcagtcatca tcgcttctgt tccgcgagaa actcctgaga cataatgtcc
    20461 agctagcaaa tcacggatag cgttcgtaat ttgaactcca ggaactaaag gcatcacaca
    20521 tccgataatg attagatcct gattgcttcc taagccaaaa cgtacgctgt agatagcggc
    20581 tatgccaatc aataaagaag ataaaaattc cgataaaaat ttgattctaa aaaatttcaa
    20641 actatataga taagctgcgt atcccaatcc tccaatgact aaagtcacag gtaaatcggt
    20701 catctttccg ccaaataaca ccataattgt tccactgatc actgccgcgc taacgatttg
    20761 caaccagaca ggaaagaaag aacggtctcg gtcgattgct tgcagttcgc agtaaagttc
    20821 ttctaatgtt agctctgaag caacatattt acgtgaaaga tcatttactt ttactacttt
    20881 ttctaaatta atcgaacggt tggtaatttg ttccattcgg atggtcgagg tacgatcaag
    20941 accaataaag agaccggttt gagtgacata gctgaccaaa cggaaatttc cagaagctaa
    21001 agcaattcga ctcatcgtat cttctacccg atacatctcc gcattgcttt ccatcatgat
    21061 tttcccagcg agtaaacaag tgtccagcaa cagatctaat tcttttcccg tcatagcatc
    21121 ttctccaata attgattgat tagttttatt ttactacaaa acataccaga agcgtaaaga
    21181 ataaaaaaac ttgaggaagg aataaaagag gcgtatactg tttttgtatt gcgggtgtag
    21241 tttagtggta aaatcccagc ttcccaagct gatgtcgcgg gttcgattcc cgtcacccgc
    21301 ttaaaatagg ttgtgaaaaa gctgctctgc aacaagtaat aagaacagcc aagcaaaaac
    21361 aacttcttat gtttttaact tggatggact tattaccgca gatgcaagct tttgcgcacc
    21421 gtttaccaag cggttgtgaa atcagtgtat tgtcttgagt atgaagaaaa tttttgaata
    21481 ataataaata ccttacagat agagtggtga ctgattagag acgaggaatc cgtctctttt
    21541 ttgtattttt aagccatctt aaaacaggtt ttattttttg ctgtttctat ttctttctag
    21601 tatttattta taggggaaca tatgttaaga tttagggagc tgttagtaaa ggagtaaaga
    21661 aatgagcaaa aaaacaacca aggcgatcgt ggggatcgtc gctgctgtga ttgcaggggc
    21721 attcggtgtt tccaccacac aaaaagattc agatatcttt cagcagatta caactatttt
    21781 tgattccaca ccacaagctt ctcaagtagc ggatgtgcca gaatatgatg gaaaacatca
    21841 agaaatagaa atcaatggga atcagccgga atttacaaaa gaggatctta gcctttccaa
    21901 aggaacatgg gaaagctatt caaatattga taaattgaac agagtaggac aagccaatgc
    21961 tatgcttgga aaagatttgt tccctactga aaagagagag cctttgtata ttgacccgac
    22021 aggttggaaa caaaagaaat taagtgacgg gcaatggtta tataatcgca gccatttaat
    22081 tggtttccag ctgactggtc aaaataacaa cattaaaaac ttgatgacag ggacacgttc
    22141 gttgaatgct ccatacatgc ttgctcacga aaatgatatt gcggcatata tcaaagaaac
    22201 aaatcatcat gtacgctacc gtgtcactcc tcattttgag gggaatgaac tggtagccag
    22261 gggagtgcaa ttggaagcag aaagcattga agacaaaaaa attgaattca atgtctttat
    22321 ctacaatgtt caagatggct acacgatcaa ttatgagaca ggacaagcaa caaaaacaaa
    22381 aaattagtag cagctattcg aattttttat gaatattatg aaaaaattgt gtaaaaacat
    22441 acattcaaag aaatatagcg tatactttat gaaaagagta cttttgataa agctacagaa
    22501 aaaaggaaaa aaacatacaa atagtgtttc ttaatttatt cggaagtttg gaatatttgt
    22561 ttgtagtttt ccctttcttc gagtaaaata aggttgtaga aggtaagctg gaattacctt
    22621 gcgggaaaga ggtgtagaat catgggtttt acagatgaaa ccgtacgttt tggttttgac
    22681 gatagtcgca aaaaagaagt gagcgaaaca ttagcgattg tttatcgggc tttggaagaa
    22741 aaaggctaca atccaatcaa tcagattgtc ggctacttgc tttctggaga cccgtcctac
    22801 attcctcgtt atcgtgatgc tcgaaatttg attcgccgtc acgaacgcga tgagatcatg
    22861 gaagtaattg tcaaggacta cctctcaaat catggagtga atttatgaga gtaatgggct
    22921 tggatgtcgg ttctaagaca gtaggtgttg ctatcagtga cccctttggc tggacagctc
    22981 aaggagtaga gatcattcgg atcaatgaag cagaagaaga gtttggcttt gatcggttga
    23041 aggaattagt agcacaatat gaagtagacc ggtttgtagt tggattacct aaaaatatga
    23101 acaattccat cggaccaagg gcagaagctt ccatgtcata cggagaaaag atcaaagaac
    23161 tattctcctt gccagttgat tatcaagatg aacgattaac cactgttcag gcagaacgta
    23221 tgctagtaga gcaggcaaat acttcaagag ccaaacgaaa aaaagtcatc gataaattag
    23281 cagctgtgat gatcttacaa aattatttag acggctcagg taagcaatta ttttaataat
    23341 aaaagaaaag aggtaatctt atgacagaac ataaccattc ccacgaccat gaaggacacg
    23401 aacacatcac attggtggat gaccaaggaa atgaaacatt atatgaaatc ctactaacag
    23461 ttgacggaca agaagaattt ggacgtaact atgttctttt atatcctgct ggtgtttcag
    23521 aagatgaaga tgtagaatta caagcttatg catacatcga aaacgaagat ggaacagaag
    23581 gcgagttaga acaaatcgaa acagacgcag aatgggacat gattgaagaa gtattcaata
    23641 cattcatggc ggaagaagaa gaatagacta taaagctagg agaaaccttg atatgatagg
    23701 gtttctcctt tttttatttt ttactgtatg ccatattgta tgccatctag tcaatattta
    23761 agtgttgtac taatttttca acagtctttt ctttcgtttc ttttgccaag tgaccgtaac
    23821 aatcgatcgt ctgactaatt tttgtatgcc gtaatctagt ttgaacttct accatagtag
    23881 ctccagcgtc caagagcatt gaagcatgag tgtgtcttgc tacatgcaca ccgagaaatg
    23941 gaaccatagc tttttcacaa atagtaatca atcttgcata aatagcgtgg tgtgtgatta
    24001 gttctttata gataccacaa aaaatcatag tcggatcagt tacaccaagt gtcagcatat
    24061 atttccgctg attaatctgc cattttttta atatagaaat tgttctttca tctagtggaa
    24121 gaaccccagc actacaatca gttttaggat cactgatttt atagccattt ttggattggc
    24181 ttagtgtttt attgatggtg accgtatttt cttgaaaatc aatgtctgac caattcaatg
    24241 caagggcttc actgatccta accccgctat aaaagagaaa gcgtagtaac gttttatcaa
    24301 agtcgtttcg ataagtttca ggtttgctgt ttaggtaatc aaacaaggtg atcagttgtt
    24361 ctttactgta aactttgacc ttttctttat gcttagtggt ggttctttta ggcattaata
    24421 cgttgtctag tggattagtc tcaataatcc caagattgat agcgtagcta aaaatacgct
    24481 tagaagttga atgaagtacc ttgtattggt cagtagtttc agcccagcta tttacaattt
    24541 gttgggcttt ttttaccgtg acttcattca cacgaagatt tccatatttt ggaagaatcc
    24601 actttctaaa cttgatttca gttttcatga aggtggcttc tcggacagtg gttttatatg
    24661 tttctagcca caagtcataa acttctttaa acgtttcgtt gttcgctttt ttaataccgt
    24721 ttttatcgta gtccacttgc aagcgtgaca aggcaagctg ggcttctttt tttgttttgt
    24781 aacctcgtct acgaacctta tcaggtttgc cagtcatttt gttcattcca agataggctt
    24841 catagagcca aaatttacct tttttagttt catattgctt gaatgttgcc ataatagttt
    24901 tccctccata gtgtagcaag ccgtgggggc ggttggagga ggcagtttat tattattttg
    24961 aatagtgttt atttagctca gtaacaagag ctgtgaactc ttttagaaga tcattttcat
    25021 aaaattcttg atactctttt ttctcatctg tatttttttc tgaatcatta attaatgagt
    25081 catatcgtaa aagcgtattt agaagagctg cgagataagc aattggggta ctcccgtcag
    25141 gaaattcaat tcgagatcct gttttaagat attttattgc gtttgttaaa taaatcttct
    25201 gtgagacagt caggttatct tcttcgatgt tattgatagc attagaaaga ttagaatcaa
    25261 ttatagagtt atttttttca atagtttttt tcaattgctt ttcaagcaca tttcgcttaa
    25321 tttcgggcat catatgcata tctcttaatg tataagatcc gtttaataga taggtagtgg
    25381 atacatctaa tacctttgaa agttgtttaa gcctggtgtt attgggaaga ttatagccat
    25441 tttcccaatt actaacggca cctttactgg ccggtgggga taatttacct ccaagttgtt
    25501 ccattgagag tcccttttca attctagcca gtctaattct ttgtcctgtc tccactgctt
    25561 cggggtattt ttttctagcc acattttcac caccattcat atattttctc tactatatca
    25621 cgatttaaat atgtgtgaaa cataaaagtt caaaaaagta tgttaaaatt cttgcaaatg
    25681 aaaaggtatg atggtatatt gagtttataa gaggtataga aatgtattca agagcctctt
    25741 gcattttttt aaaatctttg tatagaaatg tatgctaacg aggggggata aatatggaat
    25801 taaaaattga caaactcacg cttgatgatc cagcttttaa aattattgac gatcgagttg
    25861 ttcaacaagt agagcaaact caaggaacgt tactttcatt attagaaaaa aagtaccagt
    25921 ttccaaaata tatgaacaag gcacaagctg ctaagtatat gaacgtttca tacaatacta
    25981 tgatgcagaa atatgttcct aacggtttaa agttgattat agttgatgga gtcgtaagaa
    26041 tttcacaaga tgaatgtgat cgctttatgg aagaatacca aaaataaacg caagccgtgg
    26101 gggcaaaggg attaatagga ggaaataata atggaatcga cacaaaataa agcaatcgaa
    26161 aaagtattat caacaattct tacagaagac acagcggcag aattagcaaa cttggaaggc
    26221 aaagcgctag aagaaacgtt tgaatgtttg tacgaacaaa tggactatca aaaattgcta
    26281 ccacaagaac caacggtaag cggagtattg cgtggcttga acgatttagt acaagcagag
    26341 tttaaagaac gactttctat tgaagagtat caagaaattt tgtatcagca agttgagttg
    26401 ttagcgagct tgctagggct tgaactggag gacgttgaat gaaaactgaa atttggaacg
    26461 gacacattat aagatttgtc gatattaatg atgaatggtg ggcagtggcg aaagatgttg
    26521 cggaagcgtt aggtcttaaa caggttacta gagccattca ctctttgcct aaagatgggg
    26581 ttactactag taaggtcatc gattcattgg gcagaacaca agatgtaaac atcatcaacg
    26641 aaaaaaaata tttaccgcat ggcattcaaa agccgtaaaa aagaagccga ggcatttcaa
    26701 gactggattt tcgacatcat caaagaacta cgccagtcca caggacttga aggctttcaa
    26761 gtattccgca tgctagacaa agaacaccaa aaagaagcaa tgactaaatt aagccacgct
    26821 attactgaac caaaaccagt agactacatt aaagcgaatg tgatagccaa taaagctgta
    26881 tcaactattt atggtcattc caaaatggta aaaaagaaag atatgactcc tgaaatgttg
    26941 gttgatcgtg aacctatttt agatgagaca gtagaattaa tgactgttaa agaaaaatat
    27001 gggttgcagt tttcagtgag tgagaaaatt tataatcgtt ctgctgaatt gcagacaact
    27061 taggagcatt aacatgatcg agaacaaaga aaaagcctta tccataacag tcttggcgga
    27121 caggataaag gcaacttaat tgggataaaa cccgatattc tttgttccga ttataccata
    27181 ttaaaaaatc ggagggaacc attatgaaac gaaacttaat tataggaagc attttaatcg
    27241 gcggaatttt cggcttatta ccattaattg caaaaatagc tatctttgca ggattagcgt
    27301 tatatctctt cactgcttat gacgagtacg actatcaatt aagaactgga gggcataagt
    27361 agatgtacaa aacaaaacta ttaaaccaac tcgatagcct tgaattagag gaaattaatc
    27421 aagggatcgc tgaactagaa aataatatcg ggaaaaccta ctttggaaat tcattcaatg
    27481 aaaaactaac agttttgtat gtactcaaaa aacatgcaga acacaaaata atttgtcgag
    27541 aaatcaacga gctaaaaaat cagattttaa ccgcatggtt aaacattact gatatgcaag
    27601 aagcaagggt gaaaacattt aatacatggg taaagtatca gaatcaatta aaaggtgctg
    27661 aatttgttcg ggatgggttg aaatacgaac ttgagcagtt gaagctcatg gaggtgtctg
    27721 aatgatttat accagtattt tgaaaaagga ggagaggttt attggcaaat aattatcaag
    27781 cagcaacgga attacaaaag tcgggatggt caatttatcc cttatctcct ggaactaaaa
    27841 ttccaataaa aggctctagt ggttggaatg atgcaactaa cgattctaat caaattaatg
    27901 aatggtggac ggaagatgca actagaaata ttgggttaat gcttgaagat catcaaatgg
    27961 tggtagttga cctagatcaa cattctgaaa cacgaaacgg cgttgagaat tataaaaaac
    28021 ttgcttcaat gtatgatcca tttccttcta cttatacgga aatcacacca ggtaaaggaa
    28081 tccatttctt ctttaaaatt cctgatggtg taattatcca acaagaaaca ggtgcatttg
    28141 ctgatatctt cgggcgtgat gataaaggta aaagtttaag cgggattgat attatcacta
    28201 aaggagttcc aatagcgcca actatgatta tttcaagaag tgttgggaga gcatatgaac
    28261 ctattgaaaa cgtatctcta aataatattg caccagctcc cgattggcta gtgaacctac
    28321 tgctaaaaaa accgcaagaa ataaagactc aataccgacc cgtagcaaaa acagggacag
    28381 caaaaaaatt agatatgatt gttcaaggcg ctggcgaagg tagtagaaac gatcatttaa
    28441 ctaagttatg cggttggtta ctatggcacg gtgtagataa tcaaacttta gcagaattga
    28501 tttatacagc aaatgcgtac aatgaaccac cgctaaaaga taaagaagtg aatcaaatta
    28561 ttcgatcgat gattaaaaaa gatttgaggg ggaaagctca tggctcataa gcataaatta
    28621 gatagtattt tagactttcc cgaagccagc gagcgtgaag acaatatcat tgaattgaaa
    28681 acctggatgt cacgattaag atgcaataaa gacgatcaga ttaaaagtaa cagtgttgtg
    28741 aatgcagaat tgattttaac caatgatagc aatttagctg gaacaattgc ttataacgaa
    28801 tttagcggat acattcacct attaaaagat tctccttgga tcaatcgtac cgctggagaa
    28861 tgggaagaca gttttgagga tgccttaacg gcatatattg aagaaaacta caatgtagtt
    28921 tttgatgaca acaaaataca caaagcagta gtaaatgtgg ctagaaagaa tgttttcaac
    28981 ccagtaaaag aacgtatcga aaaagttaaa tgggatcaac agcctagact ggaaacactg
    29041 tttattgacc ttttaggggt agacgacaac ctttacacac gagaagtaac aaaacgttgg
    29101 atagtcggat cagtcgcacg tatctataaa ccaggaataa agtttgagat cgttccagtt
    29161 ttggatggac cgcaagggat tggtaagagt accgttccag cattacttta cacggatgat
    29221 tttttcaccg attcattaga ttcgctaggt gaaaagaaag atgattatat gcagcttcaa
    29281 ggcaatgtaa ttattgaact tggagaatta tcttcaatga acaaaactaa aattgaacag
    29341 ataaaaaact tcatcagtgc caagatcgat aaaattagac ctccttatgg tcggaatgtc
    29401 atagcttggg caaggcaatg tgtatttatt ggaacgtcga atgatgggca gtatttgaaa
    29461 gatgatacag gaaaccgccg tttttatcct ttgccttgta agaataagcc aaagatgaat
    29521 ccgtttaaaa caaaggatga atattttctt caagtgttag ctgaagcaaa ggtgcttttt
    29581 gataaaggac aacgaatcta ttttagtccc gatgaagata aagaagtctt agaaattgca
    29641 aaagactatc aagaggatgc caagatggag aatccaatta aagaagcaat cactaaatat
    29701 ttggaaatgg aaatcccgta taaatgggaa gaagctccag cgtgggcgag acgttcttat
    29761 tatcagaact atcctgacag taaatgtaat gagaaaaatt tacagcattt ctataatgga
    29821 gctactatgc aacaagagtt ttatttagtt gatagcgtac tcaccgctga tattttggaa
    29881 gctgtttttg ataaacaagc aaaggattta ttgaatggtc gatcagatgc agaaactaaa
    29941 aagattgcct tgattattag cagtattcct ggttgggaac ggaagcaact gccaaaaaga
    30001 aataaacgac gaggatttta caataagtca aatgcctatg aaaataaaaa tcgagctgga
    30061 aagtacaaaa agtaacgggt agtaacgggt cagtaacacc tagcccgtta ctagtttacc
    30121 cttactgccc caagggatac agcaatttgg taacggggta acaccttatt tccttaaaac
    30181 ttttgaaata gttagctaat atgctgggga ataatgttac tggattttac ccgttacctg
    30241 ttaccaaaac gctagaaccc ttgtccccgt tgggattgag tggtaacggg tacctgttac
    30301 gtaggtgtta ccacgtgtta cgaatcaagg aggaaagtaa atgctcaata ttatttcaac
    30361 aaacaaagca ccgaactttc aatatacaga tgaaatggat cggtttctaa tgaacacgct
    30421 ggcatttagt gtgggattgg taacagaaga ttattccaca tttgatccag aagtattaaa
    30481 gataatggaa gaagaacctg attggctgca ggagtcagta gcgtggtgtc aatcgctagt
    30541 agtgggatca ttggtagata gtggcaacta tgatgataca ggtgagctaa tggatgaatt
    30601 taattgtctg cttaacctat atgatcgagc gagacaacga gagcttacat cgaatgagga
    30661 taatttgttt ttaaacatcc atgataagtt cttggctttg ctactaacag atgatgaatt
    30721 gataactaat ttattggagg tagaataatt atgcatatgg aaagtattag atacttcgat
    30781 ggtgagaaac acattgagta ttcaaacact caagaagatg tagactttat tagttttgag
    30841 gaagataaaa tcactaaagt taattttaaa gacggaacgt gcttgaagat agtttcgcct
    30901 tatattgaat acaaatcaaa atgggaacaa gatgattctg acgaacgaga tcgctttggt
    30961 tggtaatcta tggcagttaa aaaacaatgt aatcatgctg gatgtaaaac attgattgat
    31021 tataggcaga agtattgtgg gaagcataaa gcaaagcaaa cggcaattaa gcgtgaagaa
    31081 agaaagcaaa gcgaaggtaa atattttcaa ttctatcaaa gtagaacatg gcgaaaggct
    31141 tcatacttgt atcggttaaa tcatccagta tgtgaggatt gcctagaaga aggcttgata
    31201 aggaaagctg atgttgtaga tcacaaaatt gaactaaaag atgattggaa tagacggtta
    31261 gatgaaacta attttcgttc tttatgccat gcacaccata attccaagac agccaatgaa
    31321 agacaaagac gagaaaagag taccctttga gttaaggggg catagtgtga aacttactga
    31381 caatcgatgc ctactcattt tggtacaaat aaccgttgtg aaaaggcata agggtaatta
    31441 caaataacga ttacacttgt aatcacaagt gaaaaagtat ataatgaaag taggagattt
    31501 attgaaaaat acaattgtta ttactgataa aacagggaaa cagcgcacca ttgagttacc
    31561 tcattttggt caagtgacca ttcaaatgca gaacggaaaa atcatttata tagataaatt
    31621 agataaagaa aaattctgat cgaaaaacga aggaatgtga gcttaattgc ttacgttcct
    31681 ttttcttttg tctgaaagga ggacaacatg ggacacccta aaatattaca cgatacaaaa
    31741 ggcaatatat caagtgaaga aaaagcaatc cgtgtggacg ctagagaaga attgttcaag
    31801 cagcaaccat taataaatat cacgccccct gactggatgg cagcgagcgc tagaagtgaa
    31861 tggaatcgta tcgtaccaac attaaaaaaa gattatccat tgagtgaagc agattatggt
    31921 tcattggtag cctattgttt agcctttgct cgaatgaaaa cagccgaagc cgagataaga
    31981 aaatcaggta cgtttatcac atgcgaaaac ggagtaaaga aagccaatcc agcggttcgg
    32041 gttcaatcac aagctatgag tgatttgaaa aaacaagcca cctcactagg tatgacctta
    32101 gaatcacgat caaaactagc tttgaacaag gttaaaaatg atgaacccga agacccgttc
    32161 aaagagttga tgaattcatg aatgattaca ttgagaaagt cctatcaggt aagctgattg
    32221 cacccaagaa aattatccaa gcgtgtgagc gtcatataag cgatttggag cgttctaagt
    32281 cagatagctt cccttatgtg ttcgatgaag aacaagccac caaagcgatt aaattcattg
    32341 agttgctacc atctacggac ggtaaagcaa tcaagatgtt aggatttcaa aaattcattc
    32401 taggcagtct ttatggctgg cgtactaaag aagggaatta caggcgattc aatcgagcgt
    32461 ttaccagtat gagccgtaag aatgggaaaa cgtatatcgc aagtggcatg gctgccaatg
    32521 cgttgattat ggaacaagaa ccagcagaag caaggcaagt attgtttgta agtaacgctt
    32581 tgaaacaagc taaattgggc tatgatatgc tgtctaattc acttagaaac gtggtcaagt
    32641 ctagtaagtt tttaagacca caactgaaaa ttatgaactc taagattcag cacttgccct
    32701 ctaattcgtt cgctatggca ctggctagtg aaaccagcac gctagatggg tttgcaccaa
    32761 caaccgcaat tcttgacgag tggcacgaag caaaaactcg taaaacgtac aacgtcatta
    32821 agtcaggaat gacccaacaa aagaacggct tattgtgtgt tattagtacc gctgggcttg
    32881 atttaaacgt tcctatgtac gaggaatact tattgttaga tcgtgtgcta aaaggcgaag
    32941 aacaagccga caggtacttt atagcgatat gggaattgga cgatcccgaa gaaattcacg
    33001 atcaagagaa atggatcaaa gccaatccga tttttgaaag tgaagaaatc aaaaaagtaa
    33061 tgattccaac cattcaagat gatgtgaacc ttgctttgaa acaaaataac cttaattctg
    33121 tattggtgaa aaacttcaat ttatggagac aagcgagtga ggacagctat atgattgctg
    33181 aagactggca ggcaaccgaa gtagaaccac aagatattac aggcaagccc gtttatatcg
    33241 gagtggattt atctaaaaca gatgatttaa ctagcgtttc atggatcgta ccgctagata
    33301 acggcgaact ttattgtgat tcacatagct ttgtagccac caaatatggg cttcaagaca
    33361 aagaaaagcg cgacggtttg ccttatcgag aactagaaaa agctggtgag tgttccatta
    33421 ctcaattaga aagtggaatc gtggactatg accaagtatt tcagtttatt caagatttga
    33481 ttcaagaaaa tgatttggaa tgtatgggga tttgttatga cccgtataac gctaattcgc
    33541 ttatcagtaa agctgaaaaa gccaactacc caatgttaga agtaagacaa ggaacgatta
    33601 ctctaaacgt tccgacccga acttttagag aacaagttta tgaaggcaac gttattcaca
    33661 ataaaaatac gattctcacc catgcagtga acaacgctat tttaaaaacg gataacaacg
    33721 gcattcagat taataaatca aagaacagta acaaaattga tccaatagct gcattaatca
    33781 atgcctatgt gtttgcaatg gattacttca ccacaacgga aggagcgaaa gcagacaatg
    33841 aattttatac aagtgaagaa ttttctttct aattacattc ataccgttct tttacttctt
    33901 ggattggtgt gtgtgttggt tgctatcacc ttactaacaa atgtctacta tggcttgtta
    33961 gcgctgggca tagtgcttat tggggtagcg gtcatgctaa atacagaaca gaagggaggt
    34021 taaaagatgg cattttttaa agcgagacaa aatacaacgg gagatccttt cctacaacat
    34081 gtggtatcaa tccaatcgga tgattacacc accagcttta caagcgttcg tgcattaaga
    34141 aatagtgatg tgtttgcagc cgttcgaatt attgctagtg atattgcttc aagtccgatt
    34201 caattggtca aaaacaatat gccacaagct gataatgaac tggtgaagtt actaaacgag
    34261 aaacctaatt cagaaatgga tggttggcat ttaaagtttg ctttggcggt caatatgttg
    34321 ctaaacggta atagctttgc agagattaaa cgcaacggtg aaaaggtaga agaaattcac
    34381 ttattaccta actcaagtgt aacggttact caattagata atggtacgtt gtcttatcag
    34441 attggtgata aaaaaagacg tgtgaagtct agcgatattt tgcacttcaa atatttcacc
    34501 caagatggtt taacaggatt accaccactt tatgcgttac gtgatgaact gaaaattcaa
    34561 caagctggca accgcacatt gcacaatttc tttactcgtg gtgtcagtgg gtcaggtatt
    34621 ttgaaggttc ataagtcaga tttagacgga tcagcaaaga acgcaattcg tgaaaagttt
    34681 gaagaagcca acggttcaag tagtggagat aatgctctta gaacgatcat tcttgatgaa
    34741 acaatggact acaaaacatt agaaataaac accgatgttt tgaagcttat caattccaat
    34801 gattggaaca caaaacaaat tgccaaggcg tttggtgtac cgattgagcg tttaggcgtt
    34861 gaaaatgaac attctagcac cgttcaaagt aatctccagt atatccaaag tacgctgatt
    34921 cattacttta atgtgtttgt gagtgaatta gatacgaaac ttgaaaccaa tatccgcttt
    34981 aattccgatc agttactaga gactgatcct gaaacaaaag taaaaaatgt attggatcag
    35041 gtcaaagggt cacttctcac gattaatgag gggcggtcga aaatggggct accccccatg
    35101 gatggtggcg atcgtttact agcaagtttg aactttacgt atttagatac gttggagaaa
    35161 tatcaattaa aagaacagga aggagttaca ccagttgaat aatgaagaag aaaaggaaaa
    35221 acggctgaca gaagaagctg agctaacagc cgattctccc aaagtagaga aagaaaatga
    35281 aaaacaacca acagacggca aaactatttc aggctatgcg ttgaaattcg ggcaaccgtc
    35341 aaaagattta ggcggctttg tagaagtgat tacacccgaa gcattaaaag aggtggattt
    35401 atcaaatgtg ttcttattat atggacacga ttattcaaag ccactagcta gtgtcaaagc
    35461 aggtacgttg aaattgaatg tcgatgatac aggattacat tttgaagcag agctaaccga
    35521 cacgacctat tcaaatgatg tgtatgagaa tatctcaaaa ggggttgttg attctatgtc
    35581 ctttgggttc gtgcttggat tagattcatt cgacaaaaaa gaagatggca caattgaacg
    35641 atcaatagat aaaatcaaag cacttaatga aattagtgtc gtgaccgttc ccgcttatga
    35701 ttcatcaaat gtccaagtaa ataagcgttc ttacgaatcg tttatgagta acaaccaagc
    35761 aaaacaaaca aacaatagct tagaatccac ttctaaagca caaaaggaga gtaataacat
    35821 ggaaaaaact ttaatcgata acgaaaaaac agaattgcgt gggtatgaag aatatatccg
    35881 ttcacaaggc gaagtgcgtg atggagtcac tactgtaaat gcagcggcag ttgttcccga
    35941 agaagtaatc ggtgaagtct ttgatttgaa acgttcaaat tataacttag ctcaatatgc
    36001 aacagtaaaa acagtatcaa atggacaagg taaatatcca gtagcaacta accaacaagc
    36061 agtgttagca acaaaagctg aacttgctga aattggtgat attgacgctg aaatgtttac
    36121 ttcagttgat tataaagtag aaactcgtgc tggtaagatt gccttatcaa atgaggttgt
    36181 ggaagattca gcagtgaata ttgtacaaga ggtcaaagat cagttagcga aattggtaga
    36241 aaacactgac aataagcata tcatggattt attaaaaaca ttcactaaga aaacggctgc
    36301 tacgttggac gatttgaaac aactatacaa tgtggcatta gacccagcat taaataaaat
    36361 ggtaattcta aaccaaagcg gatattacca cctagataca ttgaaagatt cagatggacg
    36421 ttacatttta caacccgatg tgacagcacc tagtggtaaa tcattattcg gtatgccagt
    36481 agtattgatt gcagatacat tgtttgccaa tcctaaagct ggaacattcc ctatgattat
    36541 gggggatatt gcacaatcta tctttgttgc tcgtagaaat caagtaacga ctcaatggga
    36601 aaaattcgat tactactcac aaggacttgc agtgatcgtt cgcaacgatt ataagaaaat
    36661 tgatcaaaat gcttcagtgt atattgagtt tacgccagtt gtaacaccaa aagtatagaa
    36721 aaatattggg cggcggttta tcccactgcc tttttttcat taggagagat aaaatggtaa
    36781 ttttggatag cataaaaaaa agtatgcgga tcgatcacac tattgatgat gactttattc
    36841 aacaattgat tgatacagca ggcgaatata taaaaagtgc tattgatagt agcgcaacgg
    36901 ataaagatat ggataattat cagcaatttg atttggcggt gtcattactt actcaacatt
    36961 ggtatttgaa ccgtcaagaa gccagcagcg aacggatacc agtaacggta caagcattag
    37021 tacaacaaat gagaggtgct tattatgcca atcattaaga atgtaaatga attgactgag
    37081 agagtcaagt ttaaaaagac aaaacgggta aaagatgaag atgggcagat ggtggatagt
    37141 gaagaaactg tatttgaatg ttgggctaat gtgcgttcac aaatgctaaa agacgtgctt
    37201 gctagtgtag gtaccattct tgaaggaacg ttgacgttta ttattcgata cgatcaagat
    37261 tatgaactaa caaacgatat gaaagtagct tggaaaaaca agagttataa aattatttca
    37321 atcaatgaag gaacggcgtt taaagattat acaacgatca tagctaaaca gatttcttag
    37381 aatgattaca cttgtaaacg ttgtgggtat ttagtataat taaggtagta aatgaagggt
    37441 tagctgcctg aattttgcaa gacttagcta gtcgaaatct attgttggac tgaaaattgt
    37501 aggtgtggtt gcaaacatgc tggactaaga aagatgatag atgatgaacg ttcaatttta
    37561 atacaggcat gctaggactg attggatggt tttggcaagc tgattgtgta gaaatcaaag
    37621 aacacgtctg ttgtggacgt gttttttttg ttataattca aaagaggtga tttaatggac
    37681 aaagcagagt ttacaaattt ttattggaag tattatctac atttagaaaa tgagtttatt
    37741 aataccacag attttgtgat gctcgatgag aataatttca aaacattctc tattgaatat
    37801 caaaaactac tactagcgat tggttcggag tgtgagatta ttttcaaaga actttgcgga
    37861 tttgatagca gtagcaataa aagcataact gattttaaag ctgttattaa atctagcgaa
    37921 ttaatgtgtt tggataatgg tgttagggtt atgaattctt taacattgac ttcactaaaa
    37981 ccttttggag atgggtggcc tgaagataca ccagattggt ggaaaatata taacagagta
    38041 aaacatggtc gttcttcaaa ttataaggaa gcaaatttgg aaaatgtgtt gtatgcttta
    38101 gcaagtctat atttattaga ggaatatttg cataagaaag taatactaga aggtgaagta
    38161 gactttataa gtccagagtc aaatctattt acgttatctt gggaaagaaa acattcgtcg
    38221 atgcaaaaag tgacgtttga aaaagtggat tcaaattatg tagctccact cattgatttt
    38281 aaagaacaag aagaaattta aaaaccccca cggcttattg aagtttttgt atgccatatt
    38341 gtatgccatt tggtttaaat cgcttgaaaa atagtgatag ataactctaa ttcatttagt
    38401 cataaacgct gttttgataa cctttatagt tctttgatat gggtttctca ttcatggcgg
    38461 aagaagaaga atagaacaaa agaatgaatt aataagatat aaaaaaaggg attgtgacaa
    38521 acgtcttgtc acaatccctt tttccaaata aacgatgttc aatcagctgc ccctcggcat
    38581 tcgctcgaaa aacggcgaaa tatgaagaac tattttgcca tttgtttctc taataatcag
    38641 gtcaaaacgt tgacttcaca gtctcttcct taaacggtgt tctcctgcca actcctcggt
    38701 cacaagtcac aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact
    38761 cggagctgaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
    38821 cggtaataag ttcaaccaaa cgaaaattat gaggagctat ttttgtttgg ctgttcttat
    38881 tacttgatgc aggacagctt tttcacaacc tcttttcgtt tagcactaaa tttccttaaa
    38941 aagtagaaaa gctttcgaag cctcgtttgt ttcttttact gtataataaa agaaaagagt
    39001 aacaatcgct aaaagatata aacaagagaa aggaaataca agatgattgg tctgatttat
    39061 tttgtggtga tcgttctggc gaacacagtt ggcgctattt ccgggatggg tggaggcgtg
    39121 ttgatcaaac cgattcttga tcttatcggc gcccattctg ttgcagggat ttctttttac
    39181 tcaacagttg cggtattcac gatgtccatt gtttcgactg tgcgacaagt atcaagcggg
    39241 aaatcactga attggcagat tgtcggttgg gtatctagtg gagctgttgt tggaggagta
    39301 gtcggcaaca ttgtattcga agttttttta cagttatttg aaaacgagaa gcatgtgcag
    39361 ctgatccaaa tttttttgac ggtattgacc ttggtttttg cgttcttcta caccaagcat
    39421 catcagccaa aatttcattt gacgtcatgg acttggtacc ttatatgtgg gggggttctg
    39481 ggctttttag ctagtttttt aggtattggt ggtggaccag tcaatgtttc tttgttgatg
    39541 ctgatgtttg cattgccaat aaaagaagca acactatatt ctctatctac gattttcttt
    39601 tctcaactgg caaaattggt aacgattgct ttaacaagta gctttatgcg ctttgattta
    39661 tctatgttgt tttatgttat ccccgctgct gttattggag gtttgtgggg agcaagattt
    39721 agcagggttt tgtctccaaa aaaagtgacc tttatttttc aagtaattgt cctcgtggtt
    39781 cttttggtca attgttacaa tgcctttgtc atcttacaaa cattaggaga atctagacta
    39841 acgcaagtca aaatcactga aacatattgt tctaaatgaa aaaaggagta tactgtgata
    39901 aaaaaattca tttaaaaaaa taaaaattgg ctggtgattt ggatgttgcg ggaaatgcgt
    39961 ttaggagatg cagaagcact acgagaaatc aatgcggaac aattaggata tgatgtacca
    40021 ttaaccgtta cggtgagaca aatgaagaaa ctgttgaagg agccagaaaa aaattttttc
    40081 ttggtctatg aagatcctac ttctaaaaaa gcagctggct atgtacaagc ggagtcctat
    40141 gaatcgattt tcagcgatcc gatgttcaat attatggcac ttgctgtgtc taaacatgct
    40201 gaaaaaagag gaatcggaaa ggccttgatg actggcgtag aagaagcgaa aagacgagga
    40261 atatcagcaa taagacttaa ttctgcagaa tacagagtag aagcacaccg attttatgaa
    40321 cgcatcggtt atcattccga taaaatgcaa aaaagatttt tgaaaatcct gtaaattttt
    40381 atcaaaaaat acctggtcat caagccgata cttgatgatc aggtattttt tttgactaag
    40441 aaagtaattg catcaagaaa cctgagatga tcaaaacgat ggcaccacca agccgattgc
    40501 ccatttgagc aaaagcaata agttccatcc gattagctgc agataagaca gctacatttc
    40561 ctgtaccacc catcgagttg ttgcataagc cagcagtaat agttgattcg attggatata
    40621 aaccaaacaa acgaccgaca aatcctgaaa ctactgaaat cgcgataaca cttgtcaaac
    40681 ataagacaac aaattgccat gtcaaagcag aagccaatac atttagattc aataacgcaa
    40741 taccgatacc ggcaagaaca gctgctgtca agtttttgac aatcaagttg ttgaacatga
    40801 tagctgcatc ttcgtaatat tctggtaata ggtttgcgat tttacagata acaacgataa
    40861 tgatcatgaa tgcgtaagca tggactttag gaacaaaata gttacagatt tgtcctaaga
    40921 tgaagaaagt caatgatacc atcaaaccga cacctaattg tggaatggaa ggttttacat
    40981 ttctaggttt tccatcgcca aggtcgcctt tttccattaa tttaccatta ccgttgaatt
    41041 ttggcattga ttgtcccgca cgagcaacta acgctgcacc aatgatagct aggacatttg
    41101 tcattgctgt cgcaggaatc aggcgggaaa tgatagaaga agcgtccgta cctaaaacat
    41161 ttgcataaat cgttgataaa ggtacagctc cggctccaac accaccagcc attgcgggca
    41221 atgagatata taaaacggaa tttgcaaaac catttccgat aagcatacct acgagtccta
    41281 cggcaaaaaa ggagacgacc attgaaataa gtgcaacggg aataaaacga acagaagctt
    41341 tcatcaatag attacggttc ataccaagga tgctaccagt aatcaaggca gcaatataaa
    41401 agtctaaaaa gcccatattg ctgacaaagt tttctgtgga ttttactaca tactcaggta
    41461 agatcccaaa tgtagcaatc gcggcagagg caaagatcgc aaaaacggag ccaccaccta
    41521 aataactttt gacgataggg atttttgttc cgataaaatg aaataaatta ccgaaaatga
    41581 ccaaaacagc gattgggcca atcatattcg tcggtaattt tcctaaagcc attgcaatga
    41641 tcaggacaag gaccatgatc aaataaaggg gcaaacttac gccggtaatt tttgttgacc
    41701 aaaacccttc ttttttcttt tcctcaactg cagttgcggt tgttgttttt tgtgccattt
    41761 ttacagatcc tttcttattc tgtatcgtat gaaaaaagcc aaagagaagc ggcaaaagag
    41821 cagtagttgg ctggctgctg ttttgccgca gtcgcttttt tctttttaga cgtcatacaa
    41881 agtttctgta tgttctttta ctataacaat cttaatcttc taaagattta tattcaggaa
    41941 cccatttagc agattcaaca gcttctttga tatccgtgat ttcttcacga ttcaattttt
    42001 gtgcaacaac tgattttgcg acagtttcag caatcgtttg agagaattca gtgatttttg
    42061 ctactggagg caagatagct gctcctggtt ttgttacatc aacgattccg cctaatgctc
    42121 gactagcttg agaaatgatt tcagcattta ctcgtgtagc tgttgaagca atcaaaccaa
    42181 gccctaaacc tgggtacatc aacgcattat ttgcttgacc gatttggtaa gttacaccgt
    42241 tatattccac atcagcagca gggatacctg ttccaactaa agcttttccg tccgtccatt
    42301 caatcaaatc ttttgctttt gcttctgcca attttgttgg attagacaaa ggcatgatga
    42361 ttggacgtgg ggtatgagcc gccatttctt tcacgatttc ttcagtgaat gctccaggtt
    42421 gggtagaagt accgatcatg atcgttggat ggattgcttt tacaactgct tctaagtttg
    42481 tcaattcatc agcattagtg aattctgagc gtttacgagc gaatgggatt tgaccaggag
    42541 tcaatccttt tgtatcttca aacaataaac cctgtttatc tacttgatag aaatgttggc
    42601 gtgcttcttc ttcaggtaca ccttgacgga tcatttcatc taaaaggatg tttgcgatac
    42661 ctacaccagc agtaccagca ccaaatgtca agatcgtttg atctttcaat tgctcacctg
    42721 atatattcaa tccacctaat acaccagcta gtacaacgat tcctgtgcct tggatatcat
    42781 cattgaaagt agtgatttta tcttcgtatt tttctaagat cgttgcagca tttcctcgtc
    42841 caaaatcttc ccaatgtaat aacaattctg ggaataattc agtagctgat tgaacgaatt
    42901 gatcaatgaa ttcgtagtaa gtttcgcctt ctacacgagc atgacgattc cctaagtata
    42961 atggattatt caataattct tcgttattag taccagcgtc gattgataca ggcaagactt
    43021 gtgcaggatt gataccagcc gcagcagtgt agaccatcaa tttaccgata gcgatgtcaa
    43081 caccgttcac accccagtca cccataccta agattccttc tgcatctgtc acaacgatca
    43141 aacgaatgtc gcgtccatct gctgcgtttt tcaaacttgc tttgatattt tctggttcgt
    43201 cgattgaaag aaatgcagca tcttgtggtt tcaagaaaat ttcgttgtat tgttcgattg
    43261 aatccgcaac gacaggatca taaacgacag gcatgaattc aactaaatgt tcgcccatca
    43321 atttataaaa caatgtccgg ttcgtattga atagattcat taagaagata cgtttttcca
    43381 aatcggtctg tttgcttaag tattgaccgt aagcttggac agattgttgt tccaatgttt
    43441 ggacagtact tggaagcata ccagtgattc cgtattttgc ccgttcttct tttgtaaaag
    43501 ctgttccttt atttagaaaa ggattattta ataagtttag ccctgtaagc atgaatgatt
    43561 cctcctaagt tttaatacaa acgaagtata ggagtcagat gaggatatag tcaaaaagag
    43621 caggtataat aaattttatt tatatgagta atagagtcaa aagaaatcaa aatagcggta
    43681 tttgttcttt ttatatcaac aatccttgct tgattactat gcgtatctct tatatgctaa
    43741 agaaagaaaa gtagaagaat aaaggatatg ttagatagat aaatagaatc tctgaagaat
    43801 aaatcacgtg atcgtgacga taaaatacac ttacgtcagg tgataaaaaa tacataagta
    43861 gaaaactaag aggaggaaca gaaaatgaaa gaagttcaat tgatcagaaa aagcgaacta
    43921 tcagaaggtg gttgcaatgc atgcggcgta gtagaagcaa caagctatac attaaagctt
    43981 ggtgccaaca aagcgataat ctctgagttg acagtaggcg gtcttgtgga cagtctggcg
    44041 cttgctgaag gttttattgg agaagatatt tatgagatgt tttcagaaat ccgtcagtta
    44101 aaaaaagggg aaaactgcat agaggttcat catgagagcc cgaatgtgag attcaaacgt
    44161 ggtgataatg agatgatctt caataatcat gtgtccgatc acaccgagct atatggaatc
    44221 gtgaatcaaa tactaactga gctttttgga ttgggacctt atgcgttcaa ggaagaaaac
    44281 ggtaatccaa aattaaacga agaatggcaa gaaacgattg aaatacaaag aaacaacccg
    44341 cacttatttc aataggcatc cacagtattt cgtaaaaggg actttgacac gacttttgtc
    44401 aaagtcccat cgttttttat ctatttgtgt tctaaacatt tctttcagag tagtaacaac
    44461 tggaatgact gaaatgtaaa cagattattt gcctgtatca atacggaaga gtaatataaa
    44521 gtgtgtaaac gctatcatat tattcattca attttttata gagggaaggc attgaaatgg
    44581 aaaaaacgta tcaagcaggt acaaatgaag gaatagtgga ttttatcaat atggaagatt
    44641 tagaaatagc cgcttcacaa gtgattccag ctggtggtta tggttacatc agcagtggtg
    44701 ctggcgactt atttacttat caagaaaatg aacgggcatt caatcatcag ctgattattc
    44761 ctcatgtatt aaaagatgta gaattacccg atacaactac acattttgac aaagaaacgc
    44821 tgactgcacc aatcatcatg gcaccagttg ctgctcatgg cttagctcat gtgaaggcgg
    44881 agaaagcttc tgcaaaaggt gtagcagatt ttgggacgat ctatacagca agttcttacg
    44941 cttcttgtac attagaagag ataagagaag caggcgggga gaaagcaccg caatggtttc
    45001 aattttatat gagcaaagat gatgggatca atttggatat tcttgaagtg gccaagcgta
    45061 atggagcaaa agcaatcgta ttgacagcgg atgcaacagt tggcggaaac cgtgaaacag
    45121 accgcagaaa tgggtttacc ttcccactgc caatgccgat cgttcaggct tatcaatcag
    45181 gagtaggcca aacgatggat gctgtgtaca aatcttccaa acagaagctt agtccaaaag
    45241 atgtagaatt tattgctgct cattctgatt tgccagtcta tgtgaaaggt gtccagtcag
    45301 aagaagatgt ctatcgttca ttagaatctg gtgctggcgg aatctgggta tctaatcatg
    45361 gtggccgtca actagatggt ggtccagcag cgtttgattc gttgcaatat gtggcagaag
    45421 cagtagataa acgtgtacca atcgtgtttg acagcggtgt acgacgcgga cagcatgttt
    45481 tcaaagcaat cgcatcaggt gcagatcttg ttgctattgg cagacccgtt atttatggat
    45541 tgtctttagg aggaagtaca ggagtccatc aagtgtttga tttctttaaa acagaattgg
    45601 aaatggtcat gcaattagct ggaacacaaa cagtagaaga tatcaaaaaa ataaaattgc
    45661 gtgagaatcg ttttatttaa gaaacaaatg acgaaaaaaa taggagtgcg gcagatgatg
    45721 ccgtactcct atttttatag ttcaaggatg tcactaatag aataatttga aacgaaaaaa
    45781 taaaattgaa atattttttc atacttaata aaaaaggaag aatattcatg taaacgattt
    45841 tattgttttt ttctctttta tacaaaaagg gtcataattt caagtaagcg gatgaattca
    45901 tgaggatttt ttgcatactg tctctactat acttaggtca ctaagaaaaa ggagtgattt
    45961 attatgaaaa agaacatgat tgggacatta ttactttcaa cacttcttct aggcggcttg
    46021 gcaacaccag cttttgctga gggtcaagcg acttcaaaag gagatattac ctttactgaa
    46081 ccaacaaata ccgtggagcc tcttaaccct actgatcctt caaaaccagt agagccagca
    46141 gatccggaaa atccagcaac tggccagaca ggtcctttaa cactggatgt agttcccgaa
    46201 ttgccatttg gtacacacga gattgaaagc ggaacaaaaa cgtatcaagt agacgcttca
    46261 aaaaacgata caccttatct ccaagtatca gatcgtcgag gtgtaggtgc agatggccaa
    46321 gcacaagggt ggaacgtgac agtttcggtt tcagattttg taaacggttc acaagttttg
    46381 caaggcgctg aattagattt tggaacatcc actgttaaaa gtacgtcaga taacgaatcc
    46441 actggaccaa ctagtcaaac tgtaactggg ttgagtaaag caagtgcagc gacaccaata
    46501 tttacagcag caaaagatca aggtctggga acatggcttt ctgtttatga tccagcaaat
    46561 atcacactga aagtgccgaa agcagcagct ggaacattca cggctgattt gacttggaac
    46621 ctcgtggctg gcccagtagc atagagtatg aaataaattc aacaaactgc ggtgaaaata
    46681 ctataggtga aggatttttt accgcagttt ttgttgaaag gatgtggtgg acaatgaatc
    46741 aaagtaaacg actgtttgtt tcgttttttt ctattttaag tctatttttc atttttccgt
    46801 caatcagcca agcaaaggat tcagcaggag actttggaat caaaccggta tttccagaga
    46861 accaaataga taaagcaatc ggttattttg atttattagt ggcaccggaa caaaatcaga
    46921 cactagaagt aattatcagc aattcttcag atgaagaacg aacatttgag gtctctgtca
    46981 atccggcggt aacgagtgat ggtggaacga tcgattatag tcaaaaaaac ccaacgttag
    47041 atgagacatt gccgtttgat gtccgtgacg ttttgctcat tgcgaaaaag gaaatcaatg
    47101 tatcagcaca tgcagaaaca actgtaccta tagaagtgaa aatcccagca aaaagcttta
    47161 agggacgtgt attagcgggt attcatgttt cacctaaaga agaagctgaa acagaaaatg
    47221 ctacagaagg agcacaaatc aaaaatcgta ttgcttataa tctcgcagtc gttttacaag
    47281 aaagtcaaga gacgatagaa ccggatctga aacttttatc aggagatttg gacgaggtca
    47341 acgcaaagcc aactgttcag cttcgtttcc aaaatcctca gcctaggatt atcagcaatt
    47401 tgatatttac gagcaagatc ttttatgaaa atcagcttta tattgaaaat acgtctaatg
    47461 catttttagt tgcaccaaat tcgaattttc acttgaatct tgatttagct ggtgataaag
    47521 caaaagccgg cgattaccgc gcagaaatca tagcaaaatc aggcgacagt aatgaatggc
    47581 gatttacaca aaactttacg atcaaaaaag aaaaagcaca aaaagtaaat gaaaattccg
    47641 tttttgcagt acaagaacaa tctttcccat ggctttatgc aggattggtt gctgcagttc
    47701 tagtgttatg gttgattttg ctgtttttgt gggtccacaa gaaaaagaaa aaaggagaaa
    47761 caacatgatg aggtgatttc gttgaaaaca tcgatcttat tgggagggat tattgcaagt
    47821 ttgctgttct tcagctggca agagccagtc caagcagata ccaaaagttc aggtacgatt
    47881 acattttatg atctaagtcc aattccgcat ccaagtggtt cagtcaatgg cgcatcaaaa
    47941 cagcagacac agctaccgat ttataaagaa tctaatcaac atggcgtatt cccggagacg
    48001 aatgaacaaa agatccgttt tctttatttg atcattggta tagaattatg gcttcttgcg
    48061 tggttgttgt tatggagaag aaaggaaaag gaggatgaac atgttgctac aaaataaatt
    48121 ttcatttttt cgctccttct tttttacttc gctttttgtt ttaagtatat ttatcttttc
    48181 accttcggca gaagctgttg gagcaacgcc tcctgccatt tcttatgatc catacacgta
    48241 tgaaaatatc gtacctccaa atggtggacg tagtgcagtc aatggcggga agcttgtcca
    48301 actaactggg gctaaccaat tgcctaaatt gactgctact tatttgaacg atggttcaaa
    48361 tgatccttgg aaaggtggca cggtccgttt tcattgggaa agccatgtga aactaacaaa
    48421 tgtacttgat ttggtgaata tcactgcaca aggatttgca tttgtggcga tcatcaattt
    48481 gccggaacat gtatcaagca gtgatgtatt aaaagcaatt gactggaaca acgcctactt
    48541 gtatattgcc ggtgccccca tcaaggttac tagcggaagt ttattatcag caggaagcca
    48601 taccttgcgt tttgggatgg ggtcgtggga tacaaatact ctattgacag atattattgc
    48661 tattattacg cgaggcgaat tcaacgtgga cgatatcccg cttcaatttg atgttacagc
    48721 taatgtcgcg aagatgacag aaaacggaga taaatatgat acgagtccaa acaaaatttt
    48781 gaccaagggt aaattacaac cttctatgtc taaaaaggcc gttttttctg ttgattttta
    48841 tgattcgaat aatattatcc aagatcgtat gttcaattcg attttagctc cagctgcagg
    48901 tagattttat cctaaattaa ctggcggaaa cttgaatcca ggagcatatg cattttctgc
    48961 aagtgcagag ataaatacgt ggaatagtta catctcacca agtgattcaa caggaaaata
    49021 taatacattt gctgatacca cagaatacgt ggatggaaat aaccagaacc ttccaggctc
    49081 taccaatagt cggacattga cgatggggct gactgaagga cgttttgatc agttgccatt
    49141 tagtcgcttt gatcgcgtag tcaactattt tacaggaaaa aacgttacac aaggagcaat
    49201 actgactcat actccagcaa gcacaagtgg attgaatcag acagccaata tcgtgtacag
    49261 tgggaaagat gcgcaaggcg gattgctttc tcctgttgct ttaaaggtat tggagcagta
    49321 caagctagac ggaacggttt taccaacaaa cttaacagcc gatagtcagt ggggaaagct
    49381 cctttcttct gcatcgtacc aagtcacggc caattggtca gcaactgaac taaaaaaggg
    49441 ttcgatccat tacaggcttt attcgaaagg aacccaaaaa ttagcgacag gatggacaga
    49501 tcaacttttc caaacgatcc aatcaaataa cgggggtgta aatacagcta cttctacact
    49561 acctgcattg gcttcagggc aatattattt tgattatcgc ttggtggacg atgtacttac
    49621 taacatgtat ccgtcttttg cgtacaaatg gcagtctgaa caagctggaa tcaccactct
    49681 tcctcaaata acagtggcta attttccatc tgtgagtgca gatagtcagc taaaaaacct
    49741 tagcagacaa cctgagacag gagatcccct gtctgctcta tcaggagata cgattcaaga
    49801 aaatgtgaca ttcacgttaa caaaatctgg ggatgcgata accgacaaaa aaatcacgat
    49861 ctcacttcct gaaaatacta cttatatcaa tggttcctta aaattaaatg gtacaactat
    49921 cgcagatacc ggcattcaac aaggagtttc tgtcccagca gatctattga gcaaaatagg
    49981 agataccatt catcttactt acaactatca attaaatact gtagatactt ctttacaatc
    50041 cgtcagcata ctgacaaagg cagctgtact ttccagcaat attacattag cagatggtgc
    50101 taagcttcct aacccagttg tccaaacatc tgctaaaaca attcttgtcc ccaaacaaga
    50161 attaacatta gttaatgtac cagatgattt tacatttggt aacgatctcc ccaaaccgtt
    50221 gaagacaagt tattatgaat caaaaggcga tttttctttt gatgtgcggg atactcggct
    50281 tccaagcacg tctccttggc aactgacagg tacattgact tctttattta agaatgatca
    50341 aggtcaagaa ttaagcggaa caaaattata cttcaatcat tctggatcaa agcaattgat
    50401 tcagcaaggt caaaacacgt tgatttatga gagtgatgga acagctaaag gagaggttct
    50461 cgttgacttt cccgataccg atggtttact cttagaggta aatagcagta cgaatgctca
    50521 acctggcgca acgtatcaag gcatggtcac atggaaactg acagctgggc caaccagcta
    50581 agtgattaga atttgtatgg atctgtgata actgtcacag atcctctttt tcaaggatga
    50641 gaaggaaact tctgctgtta aaatcagaaa tgcttgaagg agtggacttg gaacttttca
    50701 gtttgcttga aaaaaatgaa caacggcaaa tcaaactttt ccaactttta ttagaggaaa
    50761 aaggagaggt ttccgttaat aacgtactta cccgcttatc agttgatcgg gctaccttga
    50821 aagaagatct gttttattta caagctaact tggaaaatat caaacaattg gaaattgtta
    50881 tccaagaagg gaatatttta ttaatcagac atggaaatat agcagcagtc gatgtttatt
    50941 atcattgtta cttgcgctat tctacaaaat atcagatact tctttatctg ttggaaaatg
    51001 gctcatttga tcggcagaaa cttgtcatgg aacttaatat cagttcggct actttgtctc
    51061 gcagagtgaa ggaattaaat gattctttaa atgagtttca tctgaaaata aaaagcgggc
    51121 ggctgaccgg tccagaaagt caaattcgtt atttttattt ccaattattt tggtttggac
    51181 gtccctatct tgaaaacaaa aaagaataca gtgatttatc aggaaacact tttttagatc
    51241 tgctgcaaaa agagtttagt tttgctatta cagaagaagg acgattgaaa tttgaaatat
    51301 ggctttccat tatgaagaag cgaatgcgct gtacgaaaaa atccaaacca gattatagca
    51361 atcttcctgt tggattgttt caaacgacac aatttttatt ggacctccat acatttttga
    51421 cccgttactt ctttcaatat gcctttcctt ggaatcaaaa tgaaacgttg gttttttatc
    51481 ttttcatgat cagtaacttt acattagata cacataactc gcatgtccag gagtttttga
    51541 taagcgaaaa atacaaagac gacgtagtag ctcaattgaa tcgaacgttt aaacaatcga
    51601 tagaagaata tttctctttt tatgtttttc cagaagagat ttcgcaaaag attgcgttga
    51661 cagtgatgca aaatcacgct cattttgcct attttagagg atggatgaat atttttggcc
    51721 aagaaggatt aaaacagcgg ttaactgaag tagaagataa acaattcctg gttttatgtg
    51781 aaagattggt cagacaaaca tttgctattg ttgattttac tgaagtagac gaggaaaatg
    51841 cccgctttga attatttgct cgctatgcat ctattttacg gacgctgatc aagcagttag
    51901 aattacgtct gcaaattgct tatgatcttc cttatgaaag gctaatggcg gatatcgtga
    51961 aagaaatcat ccaggaacaa ttgctgaata cgatcaaata tgatttagtc gaatacgaga
    52021 aagaaaagca gtatgatatc attttgacta gccaattgaa agagtacccg tcacagaagt
    52081 ccgctaaagt ttttgtattc actagcaacg aatataatta tgatttcccc tatttgaacc
    52141 aatttttaaa agaatgttat ttagaaaaat tgaatttaag gatgaataaa acatgaaaat
    52201 cgtgatcatt ggtgcttccc atgcaggcat cacagctgcc ctaaatctaa gaaaacttca
    52261 accgaaagca gaagttttac tgatcgatga agatcataaa gatggactag gctatgtttc
    52321 aaatggaatc aacctttatt taaaaggaaa gatacgtagt ttagctgaag ttgcccataa
    52381 catgcggact cttcaagaaa gtggggcaaa actgatcacc gaatggagag taactgaact
    52441 tgatccagac aaacatcagc tcatcctcgc atccaaagaa ggaaaaaacg agaccataac
    52501 ctatgataaa ttaatcgtag cgacaggttc ctctcctgtc accttgtata aacaaattga
    52561 agctgaaaat gtctacacct ataaaaatct agtgcaatct aagcaagtac ttgccgcttt
    52621 aaaagaagca aaagaagtag tgatcttcgg tgctggttac attggattgg aattagcaga
    52681 tgctttgaga aataaaggat acattattca tctagttgat tatatgccga atgttttatc
    52741 aagatatttc gataaggata tgatcaacag ttttcaaaat cagctgcaaa ctaagcaaat
    52801 aaatttttat ccaaatgaat tcttgatcga ttggaaaaaa tcagaagaga aagtagtatc
    52861 cgtacaactt ctgtctcaaa caataaaggc agatatggtc attttttctg cccaaactcg
    52921 tcctaatacg acattgttaa aagaaaaagt ggctttgtat gaggatgaga ctgtgatagt
    52981 caatgaatat ctgcagacaa gtgatccgga catctatgcg attggagata tcgtcccagt
    53041 cagttttgac aaaaataaac ggcatctctt tttaccttta gttactcgag ctgtacatat
    53101 ggcaagagca gtagcgctaa ctttgagtgg tcagccaacc gcttacgacc tcagacaaaa
    53161 gataacagca gcagtcatta tagactactt tttaggaact gtagggctga cagaagatga
    53221 agcgccattc ttggaacaaa ataccggttc gtgttcagga gaatttgatc tatttccaca
    53281 atacgacgaa gaaaacaaaa cagtaaatgc aaagctgatc taccatccgg atacattaga
    53341 aataattggc ggacagctga taagccaaga attcttatta tcagatttga acctgcttgc
    53401 ggatatcgtg aaacacaaaa ctacgattcc acagctagca gttgaggatt ttggatttct
    53461 gtctgaatac acctctcgtt ttcactacct caatgagtta gcttttaaag tactagctaa
    53521 gagagcaaat agcaatagag tagataaaag actgtgagaa atatcacggt cttttattgt
    53581 gtggggatat aataaatatt aatcaatcga gaataaaaaa ttcatataat gaaatagcgg
    53641 aagaattttt tgagcataat attcgccaaa aatttatcaa gtgataaaat tgttgtataa
    53701 aatgattatt tcaggaggag gagttaaatg tttttagcat taaatgaaat tatgcattca
    53761 aagttacgtt atgcgttagt tgcaggggtg atgtttttga tcgcctacct ggtatttttt
    53821 ttgactgggt tagcttatgg cttagctcaa gataatcgaa cagcagtcga caagtgggag
    53881 gcagattcga ttgtgctttc gaaagatgca aattcaaatc tagggatgtc catgattact
    53941 aagaagatag cagaagaagt cgaaggtggg aaagtggcgt atcttgccca aacacctgga
    54001 gtcgtgacta gtaaagacag tacagaagaa ggaaaaatca atgttagctt cttcggtatc
    54061 gataaaaatc aattcatcat gcccaatctt gttgaaggaa aagcttttga taacgatgat
    54121 gaggcagtag gcgatattag tttgaaagaa gaatatggtc tagccatagg agatacagtt
    54181 aagttatctg gtagtgacaa gacgtttaaa ctaactggct ttacggatca tgccaaattc
    54241 aatgtctcac cagttctcta tacaaccatc aatgcttacc aagaaatccg cttcgaaaaa
    54301 gaagatacaa gtgaaaatgc acggattaac gcaatagttg tcagaggtaa aatcagtaat
    54361 ttacctgaag atttagaaca gatcaaaatt tctaaattca tcaatgaatt acctggatat
    54421 aatgcgcaag tattgacttt tggatttatg atcggatttt tgatcgttat tgcggctatt
    54481 gtgatcggga ttttcattta tgtactgacg atgcaaaaga ttaatatctt tggtgtaatg
    54541 aaagcacaag ggatcacagg aggatttatt gcgcgttctg tagtggcaca aacattcatt
    54601 ttatcatttg ttggtattct tcttggtcta ttaggaacag tgggaacatc ccttgttcta
    54661 cctgatgcgg ttccattcca aagcaattgg ctgttttttg gcgtcattag cttgttgatg
    54721 ttagtagtag ctgtgttagg cgcactattt tctgttcgga caatcgtaaa aatcgatccg
    54781 ttgaaggcaa ttggataaga aggaggaaga acatgaaagc aatagaattt aaagaagtag
    54841 aaaaaagttt ccaagatggc gaccaagtag ttaaagcatt gaaagaaaca accatgagta
    54901 tcgataaagg ggaatttgtt gcaatcatcg gtccttctgg ttcaggtaaa agtacttttt
    54961 tgactttggc aggcggattg cagacgccta gcagtggctc tgtatttatc aatgatcaag
    55021 aattcagtaa tcaaaaagaa agcgaacgcg ttaaactacg ttttaaagaa attggcttta
    55081 ttttgcaagc ttccaatctg gttccttttc tgacagtaaa aaagcagtta ttattagtag
    55141 ataagattaa acatgaacat cgtcaaaaag aagcaaacga attatttgag cagcttggcg
    55201 tggataagtt gatcaacaag tatccagaag aactatctgg tggagaacgg caaagggtcg
    55261 caatcgctcg tgcattgtac aatgatccgt ccattattct agcagatgaa ccaactgcta
    55321 gtttggattc agaaaaggca cgagaagtag tcgatatctt ggcaaaagaa tcaaaagaca
    55381 aaaataaagc aacgatcatg gttactcacg atacacggct gattgacaaa tgcgatagaa
    55441 tatttatgat ggaagatggt gtattgaaag aaaaagaata accaaaaagc aggtggaaaa
    55501 atggtccatc gatacaacaa agatacacag caaaaaattt tgaaagaagc gactgacttg
    55561 tttatgtcca agggatatct cggcacttca acaagagaaa tcgcacaaaa agttgggatc
    55621 acccagccca atctctatca ttatttcggt gataaagaaa aactatatac ggcagtttta
    55681 gaaaaccact taaaagatgt tggaaaagct ttgagagaaa tcgttcaaac aagcgaaacg
    55741 ggatttcaag taaccttgac aaaaatggcg cagtttttga ttgagacaca tctggtcgat
    55801 ttgtttctga tgcttcacga tcttgaaagc aatctttcaa aggaaacaag agatcatctt
    55861 ttctttctat ggaagaaaaa ttatcgtgaa ccttttgaag aaatcttttc agcaaaccaa
    55921 tctgtgctaa gaaatgggat ttcaaaagaa atcgcagcaa ggcatttttt cttagtgtta
    55981 gcaccttaca tcactcggtc gaaaagacct gtggaagaac cgctaaatgt ggcgcaattg
    56041 atcgatttat atttgaatgg tgtattagga gaagcgtaaa gctgttatat agggagaaaa
    56101 tagttaggtg aagaagcaag atatgacgaa gatcgttata tcttgcttct ttatataggt
    56161 agtttttcat aaagacaaat ttgttattct ctcatgatta tcagggtata tttttattta
    56221 ttatgtcggt gttccaggaa gtgttttaat ttaataacga agaaattaat tgtttgtaga
    56281 atgaaggaaa ctatttattg ggtagatgaa tcaccacgaa tagtcaaaag gagatttcag
    56341 gatatgccaa aaatgaaaaa aatcatttta gcagtaatgt tattttctac ggttatatct
    56401 tttacagccc cttttttgct tacttaagct gattttaagt tttggccctt agtctggatc
    56461 tacgaggtga gagtcaagaa tgaaaaaaat aattggagct tttgtatttg caatcattat
    56521 cattattatc tgttttcaaa tagatgtttt tggtcaaaaa aagatagttg gacaaacggt
    56581 cagcagtacg aacagtacgg ttacaaagac aaaggaatca tttgatgata cagaacaaga
    56641 gacattaatc aaaatcggaa aaaatgaccg tacactatat acagatgact cgctaactac
    56701 cccacttgca actataaacg gcggagagct ggcggagttt ctttctgaaa caaaaaatgc
    56761 ttatcagatc aagacaaatg atggctatac tggatattta gccctcgaag atggaaccaa
    56821 agtcacaaag aatatacaaa caaaaccgga agagctatct gatgcagtga ttgtattaga
    56881 tcctgggcat ggcggaaatg atactggggc attaagcaat gatgaacaaa cagaagaaaa
    56941 agatataaca ttaagtacag ccataaaagt aaaaaaggcg ctagaggatg ctggagcaac
    57001 ggtttatttg acccatacta cagatgaatt agtacagctt ggagatatat gcgactacag
    57061 tgaagaaaaa aaggcagatg tctttatcag tttacacgca gactctacgg aatatgcgaa
    57121 tgaagcaact ggaatcacga catattatta ctatggacaa gaggaaacat tagcacagac
    57181 aattgctgac tccttcactg atctgcctct ggattcaaga ggaatctcca ctgggaacta
    57241 tcaagttctt cgagaaaatc ttcaaccttc tattttaatc gagatgggtt atatgaataa
    57301 tgatagtgat ttaaaggaat tagtaacaga cagttatcag cagcagattg ctgcaagttt
    57361 gacacaagca ttgaccactt attttcagta ataaataagc ccagccaaac aaaaatagct
    57421 cctcatattt ttcgtttggc cgggcttatt atcgcagatg caagcttttg aacaccgttt
    57481 atttttttag tagcttcaaa gctttttctg tatttgcaaa gtgaagtttg gcatattttt
    57541 caagcatagg catgccgcct ttctccaata gttttgccgc tacttggtca gatttcgttc
    57601 cagctcctga tggaagggtg attccagctt cagctgatgc tttgtgtaac tcttccaaaa
    57661 agctggcacg actgatgata gaagcagcag caacagctaa atgatattgt tctcctttag
    57721 taacgaagta cagtttttct tgtaattgat ttttttctaa acgcgcatat tttttaaaat
    57781 ttgcttccgg cgtaaactga tcgatcaaaa tcgcttctgg tttttctggc tcgatttttt
    57841 ttagcagcaa atggatcgct tgattgtgca aagcgacttt catccgaacg gcattgtatt
    57901 ttggttggat ctcattgtat ttttctggag ataagacaag cagtttatag gggatggttt
    57961 tttttaagat gtcagcaagc tggatgattt ggctatcttt taactctttt gaatctctaa
    58021 caccaagttt acgtaattct gcaagctgat cacgtttcac ataagcagca catactgtta
    58081 gcggaccgaa atagctgcca tttccgacct catcactacc taaaacggat aattgactga
    58141 tattttttgg caaagaagag gctgtttttg ctggcttggc ttgtttatcc tgtgcctccc
    58201 cccatttatc agcttctatt gctgcattcg taccttgaaa catcactttt ccggatgtat
    58261 aagcggtaat ggtcgtcccg tctttttttg cagcaaagct agtataagga atctgtttat
    58321 ttaacaaata agagcgatag tatgctttca tttgactaag ttggtcgttt gttgctttga
    58381 taatgacgtt gctcataaaa ttctcctcgt ttttatacat aaaactatac cgcaactcac
    58441 gacttttcgt tttctaagag attgcgagac atagcatttt tttaaagttt atcatataat
    58501 agttaagtat gtgaaaaata tttgtggaga acggtgaaag aaccaacttc atggtacact
    58561 aaataaaact ttcatcaaat aggaggaaat gattcgtatg gcgcacgaaa aaacacgcta
    58621 caaagcggtg attgccaacc aaacatatac tattatcgga cgggaaacca agcatcatat
    58681 ggatatcgta acgaagctga tcaatgaaca gttagcagaa ttgaaacaat tatcaccaca
    58741 aatggataat gaacaagcag caatcttgat ggctgtcaat gcgctttcgg atcaattgaa
    58801 gaaacaagaa agaatcttgg agctggaaga agaaacagca gaattaaaga aaaaaatgat
    58861 caaatttaca gagcttgaaa atcgtgtgaa acgcattgaa gcaatcgaga acgaagctcg
    58921 ggaagtattg aaagaaaatg gtcaagcaga tcataccatt aaaaatcatg tggaagcaca
    58981 acagatttta aacgagaaac gaaaaggaca aattaaacaa aaatcttcta attaagatcc
    59041 ttttatcaaa ataagaaaaa tttaaaaaaa gttagaagag aaaggaacgt agcatgctga
    59101 gtttgctgat tttattttta ttgctaattg cgtttttttc tggagcacgt cgcgggtttg
    59161 ctttgcaaat catattcgcg attggatatg tattgtcatt tattgctgcc cagcattttt
    59221 acaaaccatt agcaagtcat ttggaattat acattccata cccagctgtc acgccaacat
    59281 caaagttagc attttttgat caggtatttg cctttcacct agatgaagct ttttatgcag
    59341 gaactgcttt tctgattatt ttgctaattg gctggctgct tacccgattt gtgggggttt
    59401 ttgtccatgg attgacgtat gtgccgatct tgagacaggt agactggatt gcaggaggca
    59461 tcctgtcact aatcatggct tacgttacta tatttttgat tttgcagtta cttgcctttg
    59521 ttccattaga tgtggtccaa aatcaattcg gcgagcatag tttcgctcgc tttatcgttg
    59581 agagaacgcc atttcttacc aacaagatgt atgagctttg ggtaacgaat attttgaatt
    59641 aaggaaaata gtgctggaaa atatttcgtt ttttgtacag agtagattat ttaagaaggc
    59701 tgcgtagcgt atgtccggca cagctctttt ttcatagtga aagataaggt gataaaatga
    59761 ataaccgaat ccttgaaaca ttggaatttg aaaaagtcaa acagatggtc agacaatttg
    59821 tagtgactgc acaaggaaaa gaagaactgg cagaattggt accagtgagc gaggaacaaa
    59881 cgatcacaaa ctggcttcaa gaaactgagg atggattgaa agtgcaacgt ctgcgaggcg
    59941 ggatccctat acctaaactt gaaaatatcc gtccccatat gaaacggatt gagatcggag
    60001 cagacttgaa tggagtggag cttgcacaag tttccagagt attgtctacg acaagcgaat
    60061 tgaatcgttt cattgatgat ctttatgaca gtgaaatcga atttgcacgt ttgtatatgt
    60121 gggcagatca gttagtcacg atccctgttt tgagccgccg tttaaaggaa gcaatcgatg
    60181 aagacggacg cgtgactgat gacgcttctc ctgagttaaa gagcataaga cagaacattc
    60241 ggcgaagtga acaagctgtt cgtgaacagt tagatgggat cgtccgtggg aaaaatgcaa
    60301 agtatttaag tgatgcgatc atcaccatgc gaaatgaccg ctacgttatc ccagtcaaac
    60361 aagaataccg cggtgtattt ggcggtgtag tccacgatca aagtgcttca ggacagactt
    60421 tatttattga accaaaacaa gtggtggatt tgaataatcg tttgcgtcaa taccaaatcg
    60481 ctgaacgaaa tgagattcaa cgtattttaa gtgaactttc tgctgaactt gttccccatc
    60541 gtcaagaaat catccacaat gcttatgtga ttggtaaaat ggatctgatg aatgcaaaag
    60601 cacgatttgg taaagaagta aaagctatcg tgccgggaat cagtgaagac aatcatgtcg
    60661 tcttgaaaca agcaagacat ccactgatcg atcaggaaaa agtagtttct aatgacatca
    60721 caatcggaaa agactatcaa gccatcgtca ttacaggacc taacacaggt gggaaaacga
    60781 tcacgttgaa gactttaggt ctgttacaac tgatggggca agcaggatta ccgattcctg
    60841 caggtgaaga aagtcaaatc ggtatttttg aggaagtatt tgcggatata ggagacgaac
    60901 agtcgattga gcaaagtcta tcgacctttt cttctcatat gacgaacact gtagatattt
    60961 tatcaaaagt caatgaaaaa agtctggtat tatttgacga gctcggtgca ggaacagatc
    61021 cgcaagaagg tgctgctcta gcaatcgcaa tcttagatga tcttggtaaa aagtctgctt
    61081 atgtgatggc aacaacgcat tatcctgaat tgaaagttta tggatataat cgggcaaata
    61141 cgattaatgc cagcatggag tttgatgtgg atacattaag tccaacgtat cgtttgctga
    61201 ttggcgttcc tggacgaagc aatgcgtttg aaatctctag ccgattaggt cttgatacag
    61261 aagttattga tgaagcgaag cagttgatga atgatgagag ccaagattta aacgaaatga
    61321 tcacagattt agagaatcgc cggaaaatgg cagagaccga atatctggaa atgcgtcatt
    61381 ttgtttctga ggcacaagaa cttcacgatg atttgaaaga agcttacagc tatttctttg
    61441 aagaacgtga aaaagaaatg gaaaaagcaa agaaaaaagc aaatgaagtc gtgtcagagg
    61501 cggaagaaaa agcagaaaaa atcattgctg atattcgtaa aatgcaacag cagattgggc
    61561 aaggaaatgt gaaagagcat cagttgatcg atgcaaagac ccaattagca aatctacatc
    61621 aagaagaaac tttgaagaaa aataaagtat tgaagaaggc gaaagaacaa aaaacgttga
    61681 aaccgggaga cgaagtgttg gttacgactt acggccaaag agggacgctt ttacgtaaaa
    61741 acgggaatca gtggcaagta gaaatcggta tattaaaaat gaatgtgtcc gaagacgagc
    61801 tgacgcctgt tgctcctcaa aaagagccga cacaacgagt tatccatgct gtacgatctg
    61861 aatctagtag tcacgtgccg aatcaattgg accttcgagg aaaacgatac gaagaagcgc
    61921 taagtgaggt agatcaatat ttggattctg ccattctagc tggttatcct caagtgacta
    61981 ttgtccacgg aaaaggaaca ggcgcacttc gcaagggaat tactgattat cttaaaaacc
    62041 atcggagcgt caaaagcttt gagtttgcac cggcaaacca aggcggaaat ggtgcgacaa
    62101 ttgttaaatt taagtaaagc ttactaaagg taagcagatg gttcgctatc caagtataga
    62161 aatgctatac tagtcataga ttttaaaaat ggaggtcttt gatatgtcac aagtaattac
    62221 agataagaca tttaatgaag aaacagataa aggacttgta ttgattgatt tttgggcaac
    62281 ttggtgtggt ccatgtcgta tgcaagcacc gattttggat cagttggaac aagaatatga
    62341 tgaagaagaa ttcagaattg ctaaaatgga tgtggatgaa aatccagaaa ctcctcaaca
    62401 attcggtatc atgagcattc caacattaat gttgaaaaaa gatggtcaag tagtagaaaa
    62461 agctgttggt gttcattcaa aagaacaact acgtcaaatg atcgatcaat atttataaaa
    62521 acttacagca aaaataagct gagggtggga ctgaatccag ttccgtcctc ggtttttttg
    62581 cggttgagtt aaggttattc aaattaatat tttttgagta taattacgtt gtcaggctgg
    62641 attgtttttt tgacagacat gctataataa ctttaattga atatgaaggg gagtaccaga
    62701 tgaacgaacg aatcaaaaac aaattagctt tacttcctga tcagcccggc tgttacttga
    62761 tgaaagataa aaatggaacg atcatttatg tcggcaaagc caaaatatta aaaaatcgtg
    62821 tccgctcata ttttactggt agccataata cgaaaacgga acggcttgtt agtgaaatcg
    62881 aagactttga atacatcgtt acagaatcga atatcgaagc attgctctta gagatcaatc
    62941 tgataaagaa aaatgatcct aaatacaaca ttatgttaaa ggatgataaa acctatcctt
    63001 tccttaagat aacgaatgaa aaatatcccc gtttggtgat tactcgtaag gtactaaaag
    63061 acaaagcact gtattttgga ccatatcccg atgtcggtgc ggcgaatgag acaaagaaga
    63121 tcctcgatcg attatttcct ctgagaaaat gcaaacctag tcagacgaag gagccttgtc
    63181 tttactatca tttgggacaa tgtctgtgtc cttattattt cgacgtagat ccgaaagtct
    63241 atacgaaaat cgttgatgaa gtgaaaaact ttttaaacgg aggacacgaa aaaatcgagt
    63301 cagagatcca tcagaaaatg gaaaaagctg ctgaaaacat ggagtttgaa aaagctgcag
    63361 aataccgaga ccagatccgt gccattgaga caatcatgac tcgccaaaaa atgacaaata
    63421 ctgatttact ggatcgagat gtatttggtt atgcgattga taaaggatgg atgtgtgtcc
    63481 aagtgttttt cgtaagacaa ggaaagctaa ttgaacgaga tgtttcaatg tttcctttct
    63541 ataacgaagc agaagaagat ttcttgactt acctcggtca gttttatcag gaaaatgagc
    63601 atttcattcc taaagaagtc ttgattcctg atacgatcga caagcccagt gtagaagctt
    63661 tgttagctac gaaagtgctg caaccaaaac gaggagaaaa gaaaaaatta gttgaattgg
    63721 cgagtaagaa tgcctcagtt gctttgaatg aacggtttga tctgattgcc agaaaacagg
    63781 aacggacgat cggagcagtt gaacgtttag gaaacgcgat gaatatcccg accccaatac
    63841 gtatcgagtc ttttgataac tctaatatca tggggacgaa tcctgtggct gcgatggtcg
    63901 tattcattga tggaaaaccg gcaagaaaag aatatcggaa atataaaata aaaacagtca
    63961 acggaccgga tgattatgca tcaatgagag aagtcatcta tcgcagatat tcgcgagtga
    64021 ttcgcgaagg gttgccttta cctgatttga tcttgatcga tggaggaaaa ggacaagtag
    64081 atgtggcaaa agatgtctta gaaaatcaat taggaatcga tattcctatt gctggcatgg
    64141 caaaaaacga taaacataaa acaaatgagt tgctattcgg tacagatttg gctgtagtac
    64201 cgcttgagcg aaattcacca gagtttttct tactccagcg aatccaagat gaagtccatc
    64261 gattcgcaat cactttccat cggcagctac gcagtaaaaa cagttttgct tcccgattag
    64321 atgaaattga agggttagga ccaaaacgaa aaaaaatgct gcttaaagag ttcaaatcgt
    64381 tgaaaaatat cacagcagcc acgacagaag aattacaaga aatcggactg ccgaaaaatg
    64441 tcgcacaaaa cgtatttgat aaattacatc aggaatgagg aaagggcact ttacaaagaa
    64501 agtaaagtgt cctatcattt tatgtacaac aaaaagagcg tttacgtttt gttggtaaat
    64561 aataaatcgc ttacgtctgg tgtctaagga tatatgtgat ttcttgaaga aggagtgaag
    64621 aaatgttaga agtcaaggat cttgttaaaa cttttgggaa ctacacagct gtcgatcatg
    64681 tctctttcca aatccccgat ggaaaaatca tggggctaat tggccaaaac ggggctggga
    64741 agacaacgac ttttcgtttg atcttggatt ttttgacaca agaccaagga gaagtgttat
    64801 ggaatggcca tcatcttggg gagaaagatt atgatgtcat cggttatctt ccggaggaac
    64861 ggggacttta tccgaaagta acgattcaag accaactgct ttattttgca gaacttagag
    64921 ggaaatcaag aaaagagatt gaaccaaaaa tcgacttttg gatggaaaaa tttcaggtaa
    64981 aagggaaaaa gacggataaa gtaaaatctt tgtctaaagg aaatcagcaa aaagtccagc
    65041 tgatcgccac gttaatccat gaacctaaat tgatcatttt ggatgagcca ttcagcgggt
    65101 tagatccggt aaatgctgaa ttgctaaaag atggaatatt ggaattgaaa aaacatggtt
    65161 catgtgtcat tttttctagc cacaatatgg ataatgtaga aaaaatctgc gatcatttga
    65221 tcatgttgcg aaacggaaaa atggttttga atggaaaagt acatgagatt cgtgaatcat
    65281 ttggccgtac gaagttattc ttggaatctg gtttaagcca acaggaagta gaagaaatcg
    65341 aaggcgtgaa aaaagtgatc cttcatgaag acaatacgtt agagattacc ttagaagatc
    65401 ctgaagctgg gaaagaaatc tttactcgtg cgactcagtt cggctacatt cctatgttta
    65461 accagcaacc gccaactttg gaagagattt tcaaattgaa agcaggtgaa atcgatgcgt
    65521 aagttttgga ttattaccaa agatgtctat ttaaaaaatg ttaagtcgat ttctttcttg
    65581 atcatgatat tagtcccttt tatcatgctg ggtatcattt atgtagcagg aaactttgct
    65641 caacaaaata gtgatgtcaa taaaatcggc gtattggctg ataatgagca aatcagtcag
    65701 caaatgagcc aagtcaaaac agatgatttt gagttcaaag cagttgattc tgaagaaaaa
    65761 gcacaaaaag agctttcgga agaaaaaatc gatgcgtatt tagtagtctc aactgagaat
    65821 gataagataa atgggatgct ttatagcgaa aattcattag gacaaagtac acaactactg
    65881 atacaacaac aactgactgg cttgcaatcg atgcttcgag cgagtcaatt aggcatttca
    65941 ccagaagaag tagctagctt gagccaacaa gcaagtttga ctcgacaaaa agtcaatttt
    66001 gattcaaaag gaaaaatgac agtcggagaa gataactcga cagtccaata cgtcgtaagt
    66061 tatgtagcaa cgattgtctt gttcattatt attttgacgt atgcgcagat cattgcacaa
    66121 gagatcgctt ctgaaaaagg cacgcggatc atggaagtga tcctgtccag tacgactgca
    66181 caaaagcatt tttacggaaa attaacaggt gttttacttg ttgcattaac gcaaatggca
    66241 ttatacggta ttatttttgg tataggatac agtcaattca aagatatgga aatggtcaaa
    66301 aatatattag acggtatctc attggataac ttgattggac cattcttgtg gtattctctt
    66361 ctattcatga tctttggcat tttgattttt tctgttttag cagctttatg tggctctttg
    66421 gtcaacaaag cagaagatac agcaaaagca attttgccag tgacttatct atctctaggc
    66481 ggatacatgc ttggattgat actaggagct tcagatccaa acaatatcgt tattcggatc
    66541 acttcgtata ttccattctt atcttcatat attatgccgg ttcgcttagc aaatgagaca
    66601 gtcggtatgg gtggagcatt gatttccttg ttggtacttg tagccgtaac attcttattg
    66661 atgatcttgt ctgcaaacat gtacaaatcg aatgtactcg tttatagcga aggcggatta
    66721 tggagttcat tgaaacaatc gatttcaatt atgaggaatg aacgaaaaaa agcataaaac
    66781 aatcctaaaa tacagaagga agctggacat ctattgttcc cagcttcttt ttgtatagac
    66841 ctattttatt tattttacta tattggatat atattcattg aaaatagtgt ataacaactt
    66901 tataatattg agtataccaa tttttggagg cgttttaatg gaccgttatt tagatttact
    66961 ttcagaaaaa ttcccctcaa cggaggatgt catcacggaa atcatcaatc tcgaagcaat
    67021 tttgcagctt ccaaaaggaa cagagttatt tttgagtgat atacatggcg aatttcctgc
    67081 ttttgatcat attctgcgta tcggttcagg aaatcttaaa gaaaagatca aagacctttt
    67141 ttctgaacaa atgacggaaa cggatatcag ccaattcact atttttacgg cttatccaga
    67201 atatgcatta acgactgatt ggtacaaaga acaagataaa tcgcagctga tccatcattt
    67261 gatcgatctt ttacggttta cgacagtcaa atatacccgg tcaaaagttc gaaaaggatt
    67321 gccgaaagaa tatagctata tcattgagga actcttgtat atcgatgacc gtatcaatgg
    67381 aaaaaaagac tatgtaaaaa aaatcattga acaacttgtt ttgatgaagg aagaagaaaa
    67441 atttttaacg aaacttgcac agacgatcca aaaatctgtc atcgatcatt tgcatatcgt
    67501 tggagatatt tttgaccgag gaactcaagc agccaaagtg atggatcgaa tcatggattt
    67561 ttcttctgta gatatccaat ggggaaatca tgatattttg tggattggtg cgtattgcgg
    67621 ctctgaggca tgtttactga cacttttacg gattgcagca cgctataatt atttatttga
    67681 attagagaaa gaatatgggt tgaatttacg tccattgttt tcttttgctc atcaaactta
    67741 tcagaagaat ccagtatttg cgcctaaaaa cagtaaaaat ctatccgaaa gagagcaaga
    67801 agaattagaa aaaatccatc aggcactttc tatccttcaa ttcaaatcag aacatcagtt
    67861 attggatcgt cgacctgaat ttaaaatgga cgatcgtaaa ttgctggaaa aaatcgacta
    67921 tgaagcatca acgattgatt tagaaggtca gctctatgag ttgaaaggaa cttgttttca
    67981 aacgatccag ccagatgatc caaaaaaatt cttggaagag gaacaaaaag tgattgatag
    68041 tttgatgtat tcattccagc actctttgag aatgcaaaaa catatgacgt ttttgatcga
    68101 aaaaggggga atgtatctca cgaacaatca gcatgtgctg tttcatggct gtatacctgt
    68161 agacgagaag ggacagctct tagcatttga attagaccaa tcttatcgcg gaaaagaact
    68221 gctgggcttt tttgaaaaac agataactga aagcgcaaaa gatctgactg caaaagaaga
    68281 tttagcaacc gatttgattt ggtatgcgtg gagtgggcca ttttcgcctt tattcggcaa
    68341 gagtaaaatg gcgacttttg aacgttattt tctcacagag cctcatacgc acgtcgagaa
    68401 aagcaatcct tattatcact tgcgagatga agagtggttc agtgaaaaaa ttttagcaga
    68461 attcgacaca aaagaagaag ggtcagcaat cattaatggg cacacgccag taaaagtaaa
    68521 aaaaggggag tcaccgatca aagcaaatgg aaaagtattt gtcattgacg gaggtttatc
    68581 caaagcttat caaaaaacga caggaattgc cggttattca ctattatgca attcttatgg
    68641 tttccaaatc gtgacacatt atccgttttt gcctattgaa caacaatttg caaaaaaatc
    68701 cgaccaaaca aatgtgaaaa aagtaatcga acagcaacta ccacgcaaac tcaatcgtga
    68761 tacaacaaaa ggtatggaac tgcagcagca gattacccag ctcaaaaggc tgttggacta
    68821 tcgaaaggac gattgagaag aattccagtg aacattgttc catagactgg agactgagac
    68881 aaaagtcgtg tcgcagtctc tttttccgga taaacggtgt tcttctgcca actcctcggt
    68941 cacaagtcac actattcaac aaacatgaaa agctgttttt tgaaattgct ccttgtgact
    69001 cagagttgaa cggcaggctc acgacctctt ggtataaacg gtgttcaaaa gccagtttct
    69061 cggtattaag ccaaatttat gcaaaaatgt gaaaagccat tttcacaaaa tttttcttaa
    69121 tactcgaaac taaacagctt tttcacaacc ccctcagaaa gtctattaaa attcattcac
    69181 aaagaaatcg aataagcgct gttcagatgg atgtacacgg tgggtaagtt ccggatgcca
    69241 ttgaacaccg aggattttat gcatatcatc tttgctttga accgcttcaa tgagtccatc
    69301 gttagaaaaa gcgatggctt ttaataaagg tgaaagatct ttgactgcct gatgatggta
    69361 agaattcaca aaatatggat cggggagaag gttgcttaac aaactgtctg aaacaatctt
    69421 gacttcgtga gtcgtaaatt gcggggcagt gggctgttgt tcatgtttta ctgaccactt
    69481 tggatataat gaaagatctt gataaagtgt accttccaaa acgacattca atagttggag
    69541 tccccggcag actgcaaaaa ttggttttct ttgtttcaat gcttccaaga tcagtgcctg
    69601 ttcaaattgg tctcgttgaa tatttgtttc cgttagcttt ggatgaggat cttccatgta
    69661 aagttgtgga ctgacatctt gaccacctgc aagaataagt ttgtcgattt gtccaatcag
    69721 ttgaggagct gaatctggag acatgactgg cagaataaga ggcaatcctt gagcatctaa
    69781 aactgcatcc acgaatcctt gcggtgtata gctcacttga tttccttgga aagtatctgt
    69841 tgctcgaatc agttgatttc cggcaatgcc gatgattggt ttcatttgta ttccccctaa
    69901 agtagactta ttgtaacaag gatttaaaaa aaattaaact atgtaagact tgcccctata
    69961 cttatctgtt cttgctgtgt tactatctgt aaagagaaat ttcgtgtgaa attcatgacg
    70021 atagttgaaa atattgctta atttgttata ataaaaagta agcagaaata aaaaggttgg
    70081 gcgtaagctt caaggatcta gttcttcaag gggtgagaag gacattttat tgaaggggcc
    70141 tgcctatact aagttatctt tagaggtaca tactttcaat gaaaaaagaa agcatgtacc
    70201 tcttttttaa atcgaaagga agtgaagcaa gtgttagaag ctttggaaca aatccgaaaa
    70261 gcagaagaag aaaatgaaaa gcgtgctcaa acactgcggc agcagctgaa gatctatgca
    70321 acagaaaaag agcaggaatt ggaaacgatc caaacaaact atcgacaaca actaaaacag
    70381 ttggtggaag aaaaagaaca atttgaaata caagaattag aaaaagaaaa aatgaaattg
    70441 aaagcagaag cagacaaggt gcaagcaact ttgaaagatc aatatcaaaa gcatcagagt
    70501 caagcgatcg gtgcgatcat tgaaagggtg aaagaaactt atggccgtca ctaagatgga
    70561 aaaagtgacc ctcatttcag ataaaagaaa tcaggagagg attttacaag cagtacaagg
    70621 aatccaaaac gttgaaatcc gggatctgta tcaaaataga acaaacaacc agtgggtgga
    70681 gaagtatttt ccagatacca cgattattga taaagaagca aaattaagcg ctttaggtaa
    70741 tcggttgaaa gacatccaag aagctatcca attcatacaa caccacggcg atagccgtca
    70801 aaagaaactc catttgaaac gtcaagaact ttccttacaa gatttggaag ccaattattc
    70861 cgaagaaaat ttcataaata aattgaaaga agtccttgat ttaaaagaaa agtgggaaca
    70921 actaactgaa gaacgtgatc gtttagaaga agaggaagaa tggcttcttc attggcaaca
    70981 gctggatatt gctccaagta tgtatgcaag taagacgacc atttttgaga tggggactgt
    71041 gagtgcagca aattttgaaa gtttcaagga agaactgagt aagcttgatg acgtttatat
    71101 ggaagaaata gattatacgc caaaacaagt ttatctttcg tatgttgctt taaaaaaatc
    71161 agttgctgtt atagaagaaa ttgctgggaa atacgggttc aataaagaaa cgtatcctta
    71221 tgaacaaaat cctaaagaaa aactgcaaga gaccaagcag caattatcca ttgttcacga
    71281 gcagcaaaag aagataacga cagcgttagg tcagtgcagt ggctatatcc aagaatttga
    71341 atgggtagaa gaagtcacac ttgccgttgc agaacgagaa aaaataaaag aacggtttat
    71401 ccatgcgact tatctgatcg ttttgcaagg ttgggtagat gcagaagaaa aacagaattt
    71461 gctgcatgtg ttaaacgaaa ccgtatcaga agaagatata tacgtcagtt tcgaaacacc
    71521 aaactcagaa gagattcagc aggaagtccc tactaaattg aaaaaccatc cgcttgtcga
    71581 accttttgaa ttgctgactg aaatgtacag tctgccaaaa tatgaagaag tagatccaac
    71641 accttggatg acaccatttt atcttgtctt cttcgggatg atggtcgcag atgttggtta
    71701 tggtttgctg atgctcattg ggacaatact agctcaaaaa ctacttgttc taccacgcgg
    71761 gatgaaacgt ttcgtaaaat tctttgagat tctctcgata ccatcgatca tctggggatt
    71821 gatctacagt tcatttttcg gacagtcatt accaaaagaa ctgtttggca tccgcttgcc
    71881 tttcccaatc ctatctacga cggatgacgt caatacgatt ttgattttat ccgtgatttt
    71941 cggtctgata cagattttgg ttggattatt tgtggcagca aaggaaaata tcaggagaaa
    72001 agattacttg agtgctgtca gtgatggatt tgcctggcaa gggatcctaa ttgggatcgt
    72061 tattgcgttg gttggtgcca tgttgataaa aaatacagca tttgtttacc ttggcgctgg
    72121 gctatcgatc attgctgcct tatgtatctt gatcgttccg attatccaaa cgccgtctaa
    72181 agtcaaaggt gctgccaaag gtgcgtataa tctttacgga ctgaccggct atatcggtga
    72241 tttagtcagt tatacacgtt tgatggcatt gggtatttca ggcggaagta ttggagcggc
    72301 attcaatatg ctagttgctt tcatgccgcc agctgctcga ttcagtgtag ggatcctttt
    72361 gatcatcgct ttacacgcac tgaatatgtt tttgacactg ctaagtgcct atgtccatgg
    72421 cgcacgattg cagtatgtcg aattttttgg gaagttttat acaggaggcg gacgtgcctt
    72481 tgatccgctg aaaacggcgg aaaaatacgt caacatcaat cacaagaaaa aaaacaataa
    72541 ataattggag gatttttata taatgatgga ttacttaatt agtcaaaatg gtggaatggt
    72601 atttgcggta ttagcgatgg caacagcgac gattttttca gggatcggtt cagctaaagg
    72661 tgttggaatg acaggtgagg cagcagcagc attgacaaca agtcaacccg aaaaattcgg
    72721 gcaggctctg attctgcaat tgcttccagg tacgcaaggt ttgtatggat tcgttattgc
    72781 ctttttgatt tttatcaact taggaaatga catgtcagtt gtacaaggac tgaactttct
    72841 aggtgcttct ctgccgattg cttttacagg cttgttttca ggtattgccc aaggaaaagt
    72901 cgcagcggca ggtattcaaa ttttagcgaa aaaacctgaa catgctacaa aaggaatcat
    72961 ttttgctgcg atggttgaaa catacgcgat tttaggtttc gttatttcct tcctattagt
    73021 gttgaatgcc taagcataaa ggaggaaaag cagatgaacg ccattgaaaa aatcatctct
    73081 cagatgaacg aagcagcaga gcaggaaaga gcggcgttag aacaagaaga gcgaatgaag
    73141 atcgatcaaa actttgaaca aaaacgtacg caagttgaaa cagaacatca aaaacaaaaa
    73201 gaaaaacaaa tcgaattact cgaaaaaaaa taccgtcagc taaggaatcg ccagcaagta
    73261 gaagtacgac aagaaaattt gaatgcgaag caggaatttt taagacgatt gtttgcagat
    73321 gcggtaactg aaatggaaaa ttgggatgaa tctgaacaaa tccagtttat caaaaatgca
    73381 ttgtattcat tacctttgac aggaaaagta gcattcattg ctggagaaaa atcagcagcc
    73441 tatctttctc agacgttgtt ggatgaatgg aacaatgaac ttccctttat gatggtttta
    73501 agtgatgaaa ctgttgctga tcaagcgggt tttctgataa acgatcaagg agttcagtat
    73561 aattttcttt tcagcagcct tgtacaagat atccaaggaa cgatgagttt tgagattgcc
    73621 aatcaattat tcgaataagg agggatcagt gtatggaata ccacgaacta aatcccttga
    73681 ttcgcggaag agagcttgaa cttttgtcca atgagacatt tgaacggatg attcaaacaa
    73741 attctgtcga agcacttggt gaaatattga aatccacgat ttacagtcca tatatttatg
    73801 acggatatga atatgacttc gaacagaatc ttttaaagga gcagagccgt ctatttcgct
    73861 ggttaaagga atcagcaccg gagcctgaaa tcgtttggat ctatacgatg cgttatactt
    73921 tccataatct gaaggttttg acaaaagctg agatgacaaa tcaaaatctg gaccatttgt
    73981 atatcgacga tggattttat tcattagaaa ccttgaagga tgccattcat acgcaagttt
    74041 caaatgaact tcctgaaagc attatggaca gtatacgaga agtacgtgat tattttgaag
    74101 agtctaccat tcttcaggga attgacgtga tttatgatcg acagtttttg acagagcagc
    74161 gacggcttgc cgataagcta ggatatcaag aattgctgac agaagtcatt gcttttattg
    74221 acttgaccaa tatcacaacg atggctcgag gaatattgca gaaaagaaca tatgggttca
    74281 tgacgacggt actttccagc tcgggaagta tcgaaaaaga agtatttttg aactttgtag
    74341 ataaagatat ggaagattac acgaattttc tattagagac agattatgct gattttctgc
    74401 gccctgtcat ccgtgaggga aatattgatc tcgtaaagct tgaacagttg aaagatgatt
    74461 atctaagttc attgtatcaa gaagcacaaa cccaggcttt cggaccactg ccactactag
    74521 cctttttgaa cgcaaaagag gtagaaagca aaaaccttcg tttactggtt atcggcaaaa
    74581 gaagccattt cgaatcagaa acaatcagaa agcgggtgag acaagtctat gacgcataag
    74641 atcggtgtag ttggcgacaa agattctgtt ttgccattca aattgtttgg ctttgatgtt
    74701 cgttatggta caaccaagca aaccgttcgt caggcaattg aagaaatggc aaagaatgag
    74761 tatggcgtga tttatgtcac agagcaatgt gcagcattga gcccagaaac gatcgaacgt
    74821 tacaaggaac aaatgatacc tgctatcgta ttgattccca atcatcaagg atcattaggg
    74881 atagggctgg aagaaattca aaaaaacgta gaaaaagcag taggtcaaaa tatcttatag
    74941 tatgaaaagg agatagaaat tttgcaaatt ggaaaaatca taaaagtctc cggacctctt
    75001 gtaatggctg agaacatgtc tgatgccagt atccaagaca tgtgtctagt gggagatcta
    75061 ggagttatcg gagaaattat cgagatgcgt ggcgatgtgg cgtctattca agtatatgaa
    75121 gagacttctg gaattggtcc aggcgaaccg gttcgctcta ctggtgaagc tttatctgtt
    75181 gaattaggac cagggatcat ttcacaaatg tttgacggaa tccaacggcc attagatacc
    75241 tttatggaaa tcacacaaag taatttctta gggcgcggag ttcaattgcc cgcattggac
    75301 catgagaaaa aatggtggtt cgaaccaaca gtagaagccg gagaaacggt gagtgctgga
    75361 gatgttatcg ggatcgtaga agaaacaaaa gttataaaac ataaaatcat ggtgccaaat
    75421 gggataaaag gaacgatcaa aacaatcgaa aaaggttcat tcactattga tgaaacagta
    75481 tgtgtcattg aaaccgaaaa tggtgacaaa aatttgacga tgcttcaaaa atggccagta
    75541 agacgtagtc ggccaatcaa agaaaaatta aacccggatg cacccatgat cactggacag
    75601 cgagtgattg atacattctt cccagtgaca aaaggaggag cagcagctgt acctggtcct
    75661 tttggtgcag ggaaaacagt cgttcagcat caaattgcaa aatgggccga tgtggacatg
    75721 gttgtctatg tgggatgtgg cgagcgtgga aatgagatga cggatgtttt aaatgaattc
    75781 cctgaattga ttgaccctaa tacaggagaa tcgttgatgg aacgtacggt attgattgct
    75841 aatacatcaa acatgccagt agcagctcga gaagcttcta tctatacggg aatcacaatt
    75901 gcggaatatt tccgtgacat gggttatgac gttgctatca tggcagactc cacttcacga
    75961 tgggcagaag cacttcgtga gatgagcgga cgtttggaag aaatgcctgg tgatgaaggt
    76021 tatccagctt atcttggttc acggcttgcg gaatactatg aacgatctgg aagagtcatt
    76081 gcattaggat cagaaggtcg cgaaggaagt ataaccgcaa tcagtgctgt atccccgtct
    76141 ggaggggata tttcggaacc agtcacacaa aatacattgc gggtcgtaaa agtattctgg
    76201 ggtcttgatt ccagtttagc ccaaaaaaga cattttcctt cgatcgattg gatacaaagc
    76261 tattctcttt attcaacaga agtagggaag tatatggatc atatccttca agctgactgg
    76321 gcatccatgg tcaccgaggg catgcgtatt ttgcaggaag aacagcagct gaatgaaatc
    76381 gtgcgtttgg tagggattga ttccctttca gataatgacc gtctgacatt agaagtggca
    76441 aaatccattc gtgaagatta tttgcagcaa aatgcttttg atgatgtcga tacattcact
    76501 tcaagagaga aacaattcaa aatgttgaag atgatcttga cctttggtga agaaggacgc
    76561 cgtgcgttgt cgttaggtgc ttatttaagt gagatcatgg acggtaccgt atcgattcgt
    76621 gaaaggatcg gacgaagcaa atatatcccg gaaacagaat tagaaaaact agatcaaatt
    76681 attggtgaaa tcaagcaaac gatgcaaacg atcgtttcag aaggaggcat gagcaatgat
    76741 taaagaatat cgtacgatcg gtgaagtcgt cggtccattg atggcggttg aaaaagttgc
    76801 tggtgtcaaa tatgaagaat taatcgaagt ccgtatgcaa aatggcgaga ttcgtcgtgg
    76861 acaagtattg gaagtccaag aagataaagc aatggtccaa atattcgaag gaacaagtgg
    76921 tatcaattta cgtgactctt ctgtacgatt tttaggccat cctttagaac taggtgtatc
    76981 ggaagacatg atcggtcgag tattcgatgg tttgggacga ccgaaagata acggaccaga
    77041 gatcctgcct gaaaagcatt tggatattaa cggagaagta atcaatccag tagctcggga
    77101 ttatccagat gagtttatcc aaacaggtat ctctgcaatc gatcatttga atacattagt
    77161 tcgtgggcaa aaattaccag tattttctgg ctctggtctt cctcataaag aattagctgc
    77221 tcagatcgcg cgacaagcaa cggtactcga ttcatcagat gatttcgccg tagtctttgc
    77281 tgctattgga atcacttttg aagaagctga atttttcatg gaagattttc gtcaaacggg
    77341 cgcaatcgac cgttctgtca tgtttatgaa tttagcaaac gaccctgcaa tcgaacgtat
    77401 cgctactcct cgtatggctt tgactgctgc agaatatctt gcttatgaaa agggaatgca
    77461 tgttttggtt atcatgacag acatgaccaa ctatgcagag gcattgcgag agatttctgc
    77521 agcacggcga gaagttccag gaagaagagg atatcctggg tatctttaca cgaacttagc
    77581 tactttattc gaacgagcag gaagaatccg cggactaaaa ggatcggtta ctcaaattcc
    77641 gattctaaca atgccagaag acgataaaac tcatccaatc cctgacttga ctggttatat
    77701 tacagaagga cagatcatct tgactagaga gctttacaag agtgggattc agccaccaat
    77761 tgatgtactc ccgtctcttt cgcggttaaa agataaggga actggacccg gaaagacaag
    77821 agaagaccat gcagctacga tgaatcagct ttttgcagcc tatgcacaag gaaaacaggc
    77881 aaaagaatta gccgtagttt taggtgaatc tgctttatct gatgtagaca agatctatgc
    77941 gaagtttgct gagcggtttg aaaaagaata tgtcaatcaa ggattctaca cgaaccgttc
    78001 gattactgaa acacttgatc tagggtggga actgctatcg atgttgccaa gaaccgaatt
    78061 aaaacgaatc aaagacgaca tgctggacaa atatctgcca gaagggaagt gagttctgat
    78121 ggcacgattg aatgtgaatc cgacccgcat ggaattgact cgattgaaaa aacagttgac
    78181 aactgccaca agagggcata aattattaaa agataagcaa gatgaactga tgcgtcaatt
    78241 catcctgttg attcgaaaga acaaccagct gcgtcaagaa atggaagagt ctatgacaga
    78301 agcaatgtct gattttgtat tggcaaatgc ttcgatcacg gaacctttca tcgaagaatt
    78361 atttgttttg ccggcggaaa acgttgattt gtctatcgta gacaaaaata tcatgagtgt
    78421 aaaagtacct gtgatgaatt ttgaatatga tgaacagctg acagacacac ctttggaata
    78481 cgggtatttg aattccagtg ccgaactgga tcggtcaatc gatcggttta ctaccctgct
    78541 tccaaaactt ttggaactga cagaaatcga aaaaacttgt caactgatgg cgagtgaaat
    78601 cgaaaagaca cgtcggcgag tcaatgcatt agaatatatg acgatccctc aattagaaga
    78661 aacgatctat tatattcgta tgaagctgga agaaaacgag cgcgcagaag taacaaggtt
    78721 gatcaaagta aaaaatatgg gtaccactga ctaagtggta tcttttttta aaagaggaaa
    78781 acgatgatta aacaaagcaa acaaataaag aaacgtttgc cggctgttca gcttctcgca
    78841 ttaggatttt ttctcctgat tttagttggc ggcggcctac ttaccctacc attttttagt
    78901 aatagtgggc atgggacaaa ttttatcgat gcgcttttca ctgcaacttc tgctgtctgt
    78961 gtaacgggat tgacaacatt gaatacagca gagcattgga acagtgctgg tcaatttttg
    79021 atcatgcttt tgattgagat cggcggtctt ggttttatga tggttccgat tctatgcttt
    79081 gcattgataa agaagaaagt cagtctcagc acacgtatta tattaaaaga agcgctgaat
    79141 ctagaagaag tatcaggtgt gatgaagctc atgctttaca tcctaaaatt ggcctttgtg
    79201 atccaattga ttggtacggt tgctttatct tttgtatttg tgcctgaatt tggctggttg
    79261 aaaggtatct ggtacagttt gttccatgca atctctagtt tttgtaatgc agggtttgat
    79321 ttgttaggag acagtttagc caatcaccag caaaatgttt atttgatcat ggtggtatct
    79381 gctttgatca tttctggtgg gttaggcttc atcgtatggc gtgatttact ggaatatcat
    79441 cagaaaaaga agatgacgat tcattcaaaa atcgcattaa ccgttacagg taccctttta
    79501 ttaggcggat tcgttgtgtt ctttttcaca gagcgcaatg gggcaacgct agtggaaggg
    79561 aatatgtttc aacgattggc aaacaccttt tttatgagtg tgacacctag aacggctgga
    79621 tattattcag ttgattacct ccatatgagc catgcaggtc tgattttaac gatgtttttg
    79681 atgtacatcg gcggaacatc tgggtcgacg gccggcggat tgaaaacaac tacgttaggt
    79741 gtgttgctga tccagatgcg ttcgatgttg aaaggacgta cgagagcgga agcatttggc
    79801 cgtaccatcc gacaaggcgc agtgttgcgg gcacttactt tattttttgt tacgttgacg
    79861 ttgtgtgtag tcgccatcat gattttatcg gtgactgaaa cgatacctaa aacttctggc
    79921 atcgaatata ttgcttttga ggtcttctct gcgtttggta cagtaggtct tacgatggga
    79981 ttgacgccag acttgactgc aatagggaaa ttgatcatta tagcgcttat gtacattgga
    80041 cgagttggtg tattgactgt ggtcttctct ctgatgacaa aagcacaaag aacacaatca
    80101 aaatacaaat atccagaaga aagtgtcatg attggataat ttcatcttct gacagaaacc
    80161 tagtgattta gtaaaataag aaaataaaat aatttttctt gcttcttgga tactttaagt
    80221 gcaaaatgtt cgtttatttt ttgaggcact acccgttgtt gaacctcggg tagtgcctct
    80281 tttttattga aaggaatcaa taagatttga ttcctttatt tatcaatagg ttataattca
    80341 tattttttta ttttttcttt tacgatactt agtccagaag ctaaaatttc aaggttatta
    80401 gaggataggg aaattcgaac gaatgcatct ggttgcgtac gtgtagtaaa gcgtctggaa
    80461 tgataaagtc ggataccgtt agcaagaaag tcattctcaa ttatcttagg gtcaatctca
    80521 ggatcaactg gaagaattcg atagtaaggg acacgattcg ttggtttttc tactttgaaa
    80581 agagaatcaa aaagctgatt ggctcttttt gtaagactta atttagtttc taagatccta
    80641 tttgcttcat ttgaatggag gatttgagtg atgacttcca catctaatcc agaagttttc
    80701 acatttatat taaaaattgc ttgttctatc ttgctttgga catgtactgg aactacaaga
    80761 taagcaactc gcaatccaga acaaataaat tttgtcattc cagctaagta gattgtttgg
    80821 ttaggtaata aattttggaa aggaggaatg atcgtatgtt gatagtaagt tgttaaaaat
    80881 gaatggatat catcttcaat aacccataga ccttcttttt caatcacttc ggctaattgc
    80941 tctcgtcttt tgtgagagat ttgaaaccct ataggattat tacaagaagg cataagaaag
    81001 acaccatgaa tcttcttttt tctacattcc tgaatcaata tatcaggtcg cattccttgc
    81061 tcgtcaaaat caattggaac gatctctaaa tgatataact gagccaattc aatgaaatta
    81121 gcgtatgtat atcggtctgt tgctattcta tcacctggag agaaaagtgc agaaagtgtg
    81181 atagccaatc cattttgaac accggaaaca atagatagag attctaagga cggaatgact
    81241 ccttgagttt ttaaccaatt tgctgcagta gtcaattgaa aatttgtgcc tttgggatct
    81301 tggtaattaa gcaaaccaac aagatttggg ttattactag ttgattgaat aaacgggaca
    81361 acgaatttat tacattcttc aaaagaacta accagaccaa aatcaatgat atgttcggtt
    81421 acttcattgg tagagatggt gatggactca aagacattgg gagaaataaa tgtgccactt
    81481 ccaatattcg tatacagcaa acctttctca attccatatt tataagcctt gccaacggta
    81541 gtaaaattta aatctaaata atcagctagc tctctttggg agggtaactg agtgtttttc
    81601 tgtaatttat tctttaaaat atcttgttct aattgttgaa tcaacgatcg ataataagga
    81661 cgcttcaatt tttgtttgtc tggtcgccaa gttaacgggt aattgtcata agaattaata
    81721 ggcattttct ccactcctta aaattgtata ccatacaatt ttaccattga ttgtattgat
    81781 tttagaagtt aatcttttgt gaggagggaa ttgtctatga aaattattaa ttttgaggaa
    81841 gtagtagctt cttttagttt tgaagaagcg attcaagtaa tgaaaaaatg tttttttgat
    81901 tatgaaagtg gtaaaatcag ccaaaatcct cgattggtgg aaattttacc tgacggaaaa
    81961 ggcaaaaata tgtttgcgat gatgcctgct tatttggggg agaacagata ttttggcaca
    82021 aaagtcatta ccgcttttcc ggataatcat cagtatcatt taccttctca tttaggagag
    82081 attttcttgt ttgatgctca aaacggacta cccaaagcat tgataaacgc aaatgcagtc
    82141 acctggattc gaacagctgc tgtatctgcg ctggcaacag attacttagc aaatccgcat
    82201 gcagaaacac ttgctttaat tggagctggt caacaagcat tgtcgcattt gactgcgatt
    82261 tctaccattc gtcccatcac tacagtgttt gtttacgata ttttagaaga aagacgaaat
    82321 acttttatcg ctaaagctaa aaaacagtat cctaaaataa cgtttataaa tgcaatatca
    82381 gtagaagatg cagtacgtcc agcggaaatc atttgtacgt tgacctctag taaagaggca
    82441 tttcttcaaa aagagtgggt aagggaagac gcacatatca atgctgtggg cacatttact
    82501 cctgatacaa gagagataag tacatcgttg atggaaactt ctcaaatcta tgtagatgat
    82561 tactcagctg ccttaacaga aagcggggac ctgcttatag ccatggcaga aggagattta
    82621 gaggaatctt gtattgttgg tacattaggc gaattagttt ctgagaaaaa aacattttat
    82681 aaaggagaat cgaggccgac gattttcgac gcagttggtc tagctattga agatctttgt
    82741 tgtgcagaat atatttataa caaattagag aaaggggctt taaaatgaac ttagattatt
    82801 acgtagttga tgcatttgca gatgaggtgt tcaaaggaaa tccagcagcg gtttatgtgc
    82861 tagaagaatg gctgccagaa ggtacgatgc aaaaaattgc cattgaaaac aatttatctg
    82921 aaacagcatt tacagtgaag aaaaaccaag aatttgagct tagatggttt acgccagatc
    82981 gagaaatcga tctttgtggt cacgcgacat tagcaacagc atttgtttta tttaactatt
    83041 acaaaatacc tgatgaaacg attaaatttt ctactcaaag cggtaatcta tttgtgacaa
    83101 gaattaaaga ttattattac atggattttc ctagtattat gccgaaaaaa gtgccgatat
    83161 tgtctgaata tgaagaagcg attggggcta agattaaaga agcctactta gcacgtgatt
    83221 tatttttcgt attagaagat gaaaaaacgg tggctaaatt gcagccagat tttacagcta
    83281 tcaaaaattt tgaattagga ataggagtca tcgtgacagc agaaagtgtg caaaaagact
    83341 ttgtttctag aaccttcttt ccaaaattaa caatcaatga agatccagta tgtggatcag
    83401 cacattctaa tcttattcct tattgggcag aaagaatgaa taaaacaaaa ttgtcagctt
    83461 atcaaatgtc atcaaggggc ggggatctag aatgtgaatt aaaagaagat cgtgtgataa
    83521 taggaggaaa agcagttttg ttttctaaag gtacctcgtt tatttgattt ctttcaaatg
    83581 aattaaaaat aaattggtgg agagtggcaa ccttatagct acaatggttg ttaaaaaaag
    83641 acgcaaactt tttcaattta atgaaaagtt tgcgtctcat tttaattatt ggtgtttgtt
    83701 ttttattcaa tcaagagtaa aatgccccat actaactatc ctcggatgac ttcgatttta
    83761 taaccatcag ggtcaatgac aaagtagtaa gaaggcgcag tgccaggtaa tccttttaag
    83821 tcagtaatct caagaccagc agctttatgt tgctcgtgta atttttctag atcatcagct
    83881 gctatagcga tatgaccata gccgtctcct agatcatacg caccatgatc atagttgtaa
    83941 gtcaactcta attcatagtc atccccagga agtgtcaaat aaacaagtgt aaatttgttt
    84001 tctggaaaat cacggcggcg gctttcttca aaaccaaatg ccttttgata aaattcgatt
    84061 gatgcttcaa gatctttcac tcgaacacat gtgtgagcca ttttcataga ttcatctctc
    84121 cttttccttt tactcaatca taacaaaaag aagtaaggaa atagttgatt tgtgcttgtt
    84181 catgagaaat ttctcatgta aaatggatag aaaataaaac tgttaaggtg gaaactattc
    84241 atggataaac caatttttgg tgaaaaaaag caatttgctg attatcaaac ccgttatgca
    84301 gcatatattg tcatagaaag agatcagcag attgcagtaa tcgaggctcc aaatggtgct
    84361 ttttttcttc ctggcgggga aattgaagga gaagagacga aagaagaagc gattgtccgt
    84421 gagctgatag aagaaatggg aattgtggca gaaatttctt cttatctggg agaagctgat
    84481 gagtattttt actcgaatta tcgtgcaact tattattata atccaggata tttctttgtt
    84541 gctgattctt ggaagcgtat aggagaacca actgaaaaga ccaataaaat ttggtgggtg
    84601 agccctcaag aagcgcttgt gaaattgaaa cgtggtagcc accgatgggc agtcgagaga
    84661 tggatcgaaa aaaataaaaa ctgaaagaaa gcgagtagat cagctttctc tcagtttttt
    84721 tatttattac agtacatatt ttttgattgc ttcagctaca ccgtgctcgt cgtttgatga
    84781 agtgatgaca tttgctgctt ctttgacaag agaaacggca tttcccattg ctactcctag
    84841 accagcatat tcaatcatgg ataagtcgtt ctcgttatct ccgatagcca tgatttcatc
    84901 ttgatcaata ccaaggtgct gtgcgagatt cgcaactgcc gcacctttac ttgcttcttt
    84961 atttagtact tcgaagtaat agggcgcact tttgaccgtt gtgtatttat cacggaaagt
    85021 ttgcggtaaa cgcgcaattg ctgcatctaa aatttctggt tcgtcgatca tcatcatttt
    85081 gacgatgttc atgtctggtg tcatttcttc aggtgttcga tattttagcg gcatcttgac
    85141 taaacttgct tcgtggatcg tataagcgct gatatctcga ttaggcgtgt agatcgcttt
    85201 gtcatcgatc gaatggagat gactgccgac acggcgtgcc atcacttcga tctctaggaa
    85261 atcttcatgt gtcagtccgt gacgggcgat gattttacct gatttcgttt gttgtacgag
    85321 tgccccgtta taagtaataa cgtaatcatt atcttgaaaa aggttcaact cgtttaactg
    85381 ttcctggaca cctggtaagg gacggccagt gcataaaacg atcgaaacac cttttgcaac
    85441 agcagcggca atcgcttctt ttacttcttt tgttacttct cttttctcat ttaataaagt
    85501 accatcgatg tcgatagcga ctagtttgat agacataatt tcctccaata tattttaatt
    85561 tatttcaatc aatgcgccat tacggatatg gctggcaaat tcttgataag tttcgtcaaa
    85621 taaatcataa tgatcacgca aggacggatc aaccatttct tttggaaaga aaaatcgctc
    85681 atctccttgt tcttgtcccg ctaatgcagc aacaagctga ctaacctgtg ataattctat
    85741 caaagttccg tcatttcgca aaatctcgat ttgtgtgcga tgtctgcctt gttctgggcg
    85801 ataaaaatca taaggtagat cgtagctaga attcacagca gtgtaataaa caggattata
    85861 tccgaccttt tctactaaca aagtgagttc ttggactaat tttgaatccc ggttgccaga
    85921 aaaagtagca gatttcagtg gtttacgatt caaaaaacgt ttagctaaat catttaaaat
    85981 aggatcagca gattcagacc attgagtaaa gtaagtgccc aagaccccat catcaagttt
    86041 gaggtattct tctaaagtaa agcttccgtc aagaaatggc agaagtaatt gagaatggag
    86101 ttcaaaactg ctggcatctt cttgatacaa ctcgtgtgcg cgatgaagca gatgctccaa
    86161 aattacttcc ataccacggg aaacaggatg gaagtacact tgcacataca tttgatatcg
    86221 gctaacgata taatcttcca ctgcatgcat gccactcatg gaaaaagcga tcccgccttc
    86281 ataaggacga atcacacgta atattcgggt aagatcaaat gttccatatt ctgttccagt
    86341 gaaataagca tcccgaagca aatagtccat tcgatctgca tcgatctgac tagaaatcat
    86401 ttggacaact tgtgggttgg ggtaagtttt ttggatcaca ctagctacct tttcaggaaa
    86461 accttcttct actcggttaa gaatctgata cacttctgtt tctggagaag tgatgatctc
    86521 tacagtgatg gcttcatgat tcgtatggaa gatatgttca aatgtatgag agtaaggacc
    86581 atgaccgaca tcatgcaaca gtgccgcaca taaagtcacc agccgttcct gatcatccca
    86641 gcctccgttg cctatttttt cttttgaaaa atttcgagaa aagatatcgc agattcgtct
    86701 tgaaatctca taaacgccta atgaatgagt aaaacggcta tgttctgctc cgtgaaaagt
    86761 gaaagaagaa gtgcctaatt gtttaatgcg tcgtagacgt tggacttctt tcgaattgat
    86821 caaatctaag attacttgat gctggacatg gatatagtta tggactggat cacgaaaaac
    86881 tttttccata ggcagcattt gatatttata aggggttgtc ataatgtagc tcctttatgt
    86941 tattacgttg ttccattctc tggatttggt tgttccattg ctccagctgg atttcttttt
    87001 ttagccagtc ggtagaatcc tgtaaatcac ttgcagaata cagcttttca aaagcttttg
    87061 caaatgcttc tttgacttct tttacaaaaa ggggttggtc aagcagttct tcaagtgttg
    87121 ccattgtagc aggatccact gcaggatagc catttgtacc aaagtcttct tttaaagcag
    87181 attgataaaa tcgcttcatg acttgcccgc gtttttcctg attaccgttg acacttaagt
    87241 acatcataac agaaatccca tttttgatcc gacgctgagc gataccggca aattttttgc
    87301 catggatgct taaatcataa gttccaggac aataagaatg ggtgatttcg aatgcttgta
    87361 tcggtgcctt tggaaaagcg tatttagtca ataggagcat ttgctcgtaa gcgtcatcta
    87421 tggttatttt ttttgtgtca ctttggggga aaatcaaaga aatattcaaa attccttcat
    87481 ctgatacgat ccctaatcca cctgaatttc tgatcactgg agcgtaacct gcatctttca
    87541 gtgtttggat cccgtcactt agaaaaggag ttcgaacatc cttcatacct aagatgactg
    87601 tgcagtcata ttgccagaaa tgtaaaaaga tttgctggtg ttctttagaa tattccgtta
    87661 atatatctgt taatgcaaaa ggggaaaagt cgtttttttg ataaatgtgc tgatctagtc
    87721 gaatcgcagg gttcattcaa ccggctcctt tgtataaatt catattttct acaatattat
    87781 actctaaaat caaagagttg ttttggaaaa aaggttttct gtaaaaatgg acaagttggt
    87841 tgacaaaaca aaagaaacta ggaacaatgt agctatgaga agtaaaggag aatgaataat
    87901 ggaattatca caaggaacac cgatttcaat caaattgcgt acaaaagtaa aacagcaagg
    87961 ggaagtgcaa gatttttatt ttgatttgaa agggcaaatg gtgacaattg gcgatacgct
    88021 gtacatacgt tataaagaga ttcaggagga gacgggcgat gagattcctg taacgatcaa
    88081 attagttcca gatggtcatg tacagctgat ccgtgcagga gaaatgcgga tgcgtttgaa
    88141 atttggctat aaagaacggt tagaaacatc ctatcgaaca ccatacggta tgatccagat
    88201 tgctactttt acgaaagaac tgcatgttag tttgaaagac cgtcccacag cagggaaggt
    88261 tcgaatcgat tatgatctgt tcatgggacc ggaaaaaatc ggcgaatatt atttgacctt
    88321 ggattttaca gcgtaaatat aaaagaaaag tttgattttt tgtgtctgat tttgtatgat
    88381 aaggagtaga ctgtgaaagg acgtgtcctg attggaaatt agtgtatttg aaggtgcaaa
    88441 caaaagcgaa ttatcaatga tcgaagtagc acacgcgatc ttagaacaac gtggcgatgt
    88501 catggatttt tctgatttag ctaaccagat ccaaaactat cttgggaaat cagacagtga
    88561 aattcgtgat tcactcgcac aattttatac tgacttgaat attgacggca gctttatctc
    88621 attaggggat aatcgttggg gcttgcgttc atggtatgct atcgattcga tcgatgaaga
    88681 agtaaaccat ggaatggacg aagaggatga agatactcca cgtcgccgta aacgcaagaa
    88741 agtcaacgcc tttatcaatg atgatgaaga cgcgatcgat tacaatgacg atgacccaga
    88801 agatacagat ctgacagaag aagatgacga tgatctgttt gatgacgatg atgatgaaga
    88861 tgaagaaatc gctgcttata attctgactt gcaagaaatc ggagcagatg acccgacaga
    88921 tgatgaagaa gacttgccag gaaatatcga agaagattta agtatcatag acgaagacga
    88981 tgatgatgaa gattatgaag aggaagaatt ttctgactct gaaaaagaat aaacattatt
    89041 ttcttacgag aggttgtgac agagacgatc agcctatcag aataaggagg tgtgacacga
    89101 tttttgtcac accttctttt ttgtatataa aaatcccaag taaatacata aaaaataaaa
    89161 aaattgaaac ttttagcgca ccttgtacgt catattaagt gaggcagaaa ggagtggaga
    89221 atgattttta ctggatataa gaaaaaacgg cagatcgaaa aataccgtca cctgctgaat
    89281 ggactcatcg aaactgatta tcaaaaaatg ttccgtatca cgatgaatta cgtacatgat
    89341 aaagaagagg ccttagatgt gatgcaagat agttttcata aagccctgaa ctattttgaa
    89401 aaagaaaaag agatcgagca ttttagtgca tggttttatc ggatattgat ccgcacggca
    89461 ttagatagtt ggcgcagaca aaaaaggacg cctgtggact tatttgaaat tcaagatatc
    89521 ccccaacagt tacctttaga aacttccgtt gcagagctcc atatgatttt agataaaata
    89581 gacagtccgg aaaaagagat tctgatcctc tacttttttg aaggatttcg tttgaaagaa
    89641 attgcgacta tcttggatat gaatgaaaac acagttaaaa cgaaaatgta ccgctcattg
    89701 aatgctttac gtcaaatcct agaatgaagg agagaagagt gccatgtatt cccaaaaaga
    89761 aaatttaaaa aaactaaaga aaacttataa agaacaagca attcccaaag ggcttaaaga
    89821 ggagatccgc cagcgtttta ttatcgaaga gcaatcattt ataaaagcaa agcggagaaa
    89881 gagacgtctc caagggttcg gagtatcttt ggctatcgta atgattacaa caagtagcct
    89941 tctttttaat agtcaagttc gaagctttgc agaagattta cccatcttag gatcagtcat
    90001 tgaattgatc ttaggcgaac gctttactga tcgatctgaa aaaatcgata ttcaggtacc
    90061 gaagatcaat acacaaaatg agaaagaaaa taaaacaatt catggattaa atcaaaaata
    90121 ctttcgcgaa ggacaagcag attttgaaaa agctgaaaaa gaatatggaa attttgaaac
    90181 ggatcattac caagttttgg gagattatca gaaaatcgta gacgataacc ggtttctcgt
    90241 gattgaaagg cagatcaccc aaacagcagc agatagccat gttgaaaaaa gatacgacac
    90301 aatcgacaag aaaaacagtg tccagctctc acttccactt ttattcaaag atgacaccta
    90361 tctatctgtt ttgacaaaag aagtcaaacg gcagatggcc gaacaagtca aggaagatcc
    90421 atctaagtac tattggactg agcaagatat tcaagaaggg acgatagaaa aaccaacact
    90481 tgttacgcct acacgaagtt tttatttgaa caaagagcat caattagttt tgactttttc
    90541 tcaatacgaa attgctcctg gttatatggg tacaccagaa tttgtcattc ctaagtccgt
    90601 gacaaaaacg attttggcat cggaagatta tttggatcat tagacgagaa gtagttgcga
    90661 ctagcagttt caattttcaa gtaagtacaa gtaaataata agaagagaaa aagagaaaga
    90721 agagatatag tgaaaagaaa ttatttagtt atcagtatta ttgctttatc cgtgcttttg
    90781 tttttcgaaa ttacttcggt ggcctccttg atcaccgaag taaaaggaca aacacactct
    90841 tcggagcatt cgtcacaatc tttcaaacaa tcagaacaat caaccattaa aagccaatca
    90901 actgaaacag ctaacgtcaa agaagccatt caagaatcag cggaaaaggt acaaagtcag
    90961 tcatcacaat caacacaaga cagtacaaaa acgagccgag atccggctgt caaaagcgtc
    91021 gcaatcagct ttgatgatgg accaggagcg accacaacac cgcagcttct gcgaatctta
    91081 aaagaaaaaa acgtgcatgc cacttttttc gtcttaggag aaaatacggc gcagcatcct
    91141 gaaatcgtga agcagacagc tgaagcaggg cacgagattg gcaatcacac atacgatcat
    91201 cagaatctgg ccactctttc tgcccagtcg atgacggagg aagtgacgaa agcagacact
    91261 gagatcaaaa aagtcactgg caaaaccccc acttttgttc gtccgcccta tggttctgtc
    91321 acgaatgtag gagcaacgat catccagcga ccgatcatcg aatggtctgt tgattcagaa
    91381 gattggaaga caagaaatcc tgatttgatt ttgcagaaga tccaagcaac agtatacgat
    91441 ggggcaatta ttttattcca tgatatctat cctgaaacga ttcgtgccgt tcctcaagtg
    91501 atcgattatc tgaaagagca agggtatcgc atcacgacag ttggggattt attagggcat
    91561 ccaacggctg tcgagaacta ttatggcaga aacgatcatc ggccagttca gtaagtgaga
    91621 caagtatctt taataaataa cacattttaa taagtagttg aacacataac taccttactt
    91681 gcaaaggctt aacaatatct atacaggtac aacaaaaaac tgtccaccaa ttttctttgg
    91741 cggacagttt tcacttaaaa ataaagaagc aactattcgt aaattatgct aaaatagcag
    91801 tagaacgcgt cctgagggaa tcgaaccccc gtctcaagaa ccggaatctt acgtgatatc
    91861 cactacacta aggacgcaag cactgggata attgtaacta aacagataaa aaattacaag
    91921 gggattggac aaaaaaatga aatttgagca aaatttttca caaaaacagc agcagacaca
    91981 gaaactagcc atgacgcaac agttgcaaca gtccatccaa gttttacaat ataacagtga
    92041 ggagctgttg gcattcgttg agaatcaagc aatggaaaat ccattggtgg aagttgttga
    92101 gccggaatgg cagccagatt acataaaagc ttcttcatct tcttatgaag gagaagagac
    92161 aaattaccta aatcagattc ctgatacaaa agggtcttta tttgattcat tgatcgaaca
    92221 agtccatttg aattaccgag atactttttt gaggaaaatc gttctttatc ttgtagaata
    92281 catcgatttg aacggatttt tgacgattag tttagaagaa gccggaaaag agattggagc
    92341 tacgcctatc caaatgctcg atgcgttgac tctgattcag caattagaac cagctggagt
    92401 aggtgcacgt agtttgcaag aatgtctcat gcttcaaaca gaacgagatg attatgcgcc
    92461 ggaattagct tatatcgtgt tggaagaatg ttttgaggaa ctggtggagc gaaaatggaa
    92521 agaaatcgca caacgttttt ctgttgatct acatgctgtt cagcagatat tcgactattt
    92581 acaaacgttg agtccaagcc ctggccggat tttcgaccgt agcagcgaat tgtacattat
    92641 tcctgatgtc cgggtattag tggacgacga taaaaatgta caagttatct caaaccgaaa
    92701 aaatcagcca aatatacgct ttcaagagag ttacttcaaa caaatgtcac aacaagcaga
    92761 taaagaaact gaaaattatt taaaagaacg gaaacaggaa ttcgaatggt tgaagaaaac
    92821 gatcctacaa cgtggggata caattttgcg ggttgctcaa gtcattgttt cccggcaaaa
    92881 agctttcttt atcgacaagg aacgtccaat caagcctctt acgttaaagg aagttgcaac
    92941 tgagatagat gtgcatgaat ccacggtcag tcgtgcagtc aacgggaaat atttggaaac
    93001 agacttcggt gtatttgaat taaaaaaatt tttcactaca cgaattccta cgaatagtac
    93061 agaacagaca gaagaccttt cagcagatac agcgaagaaa aagctgcagg aattagtcga
    93121 tcaagaagac aaaaacaagc cgttgtctga ccagaaattg gttgaattgc tgaaaaaaga
    93181 tgagatagcg atctcaagac gaacagtagc aaaatatcgt gatttattag gaatcccgag
    93241 ttcatcaaaa agaaaacgtt atgataacta atcagtcaaa agactagaaa aagtatttca
    93301 ctttttctag tctttttagt tgaaaaacga gagcaaaact gttagactta cagtcgtgag
    93361 gttgagattt ccctttattg atgtgaaatt cgaatagtta atttcttttt ttatcgtata
    93421 tgggtcgttt taagtctaca ttggacgtaa agtgtccaac taaggagatc gctatgctgg
    93481 atgaaataaa aatgattgaa tctgttgcac cagatattat cgaagtgttg caagaacgct
    93541 ataaaatttt acgaaatatc tattggatgc agccgattgg acgtcgaagt ttatcggaaa
    93601 gtatggggat cacagaacga gtattgcgaa cagaaacaga tcttttgaaa aatctgaatt
    93661 tgatcgacac ctcaaaaagc ggtatgacgc tgacaactaa gggcgaagaa gtttatcaaa
    93721 gccttgaaaa cttcatggat cagcttttag gtacgcatca aaccgaacaa cagttggcag
    93781 aatattttgg taaccaacgc tgtatcgttg tttcaggaaa cagcgaagag cagaccaaag
    93841 tggctgatgc attcggcgaa gcgctgagcg aagccctaga ccgactactt ccagaaggcg
    93901 agaatatcat cgctgtgatg ggaggaacta ctatggctgt ggtagccgaa caattgtcta
    93961 atctggaaaa taagaaacgg cataacctgt ttgtccctgc aagaggcggg attggtgaag
    94021 cgataactgt acaggcaaat tctgtcagtg caagaatggc tgctaaagca aacggtaacc
    94081 accgtgcact ttatgttccg gaacaattaa gtctggcaac ttacaattct ttactcaatg
    94141 agccatctat ccaagaagtc ttaaacttga ttagtgaagc gaattgtgtt attcatagta
    94201 ttgggcgtgc attacacatg gcagcacgtc gtaagatgac tgaaaaagaa ttagtcatgc
    94261 tgaaacaagc aaatgctgtt gcggaatctt ttggctactt tttcaatgaa aaaggtgaag
    94321 tcgtttataa ggtccctaga atcggcatag aattgcaaga tttggaaaaa gtcccgatca
    94381 tcatggcaat cgcgggcgga aaatcaaaag ctaaagcaat tcgagcttat atgaaaaatg
    94441 caccaaaaca aacgtggctc atcactgatg aagctgctgc aaatgagatt ttaaaagggg
    94501 taacccttta aaataaatat ttttttgatt ttcataagga ggaaatctta aatgacagtt
    94561 aaagtaggta ttaatggttt tggacgtatt ggacgtctag cattccgtcg tatccaagat
    94621 gtagatggaa tcgaagtagt agcaatcaac gacttgacag atgctaaaat gttggcacac
    94681 ttgttaaaat acgacacaac tcaaggacgt ttcaacggaa cagttgaagt tcatgaaggt
    94741 tcattcaacg taaacggaaa agaagttaaa gtattagcta accgcaaccc agaagaatta
    94801 ccatggggcg aactaggcgt agatatcgtt ctagaatgta ctggtttctt cacttctaaa
    94861 tcagcagctg aaaaacattt aacagctggt gctaaacgcg ttgttatctc tgctcctggc
    94921 ggaaacgatg ttccaacaat cgtttataac acaaaccacg aaacattaac tggtaaagaa
    94981 acagttatct caggtgcttc atgtactact aactgtttag ctcctatggc taaaacattg
    95041 aacgacaaat ttggtgttgt tgaaggatta atgacaacta tccacgctta cacaggtgac
    95101 caaatgactc tagacggacc tcatcctaaa ggtgacttcc gccgtgcacg cgctgctgct
    95161 gcaaacatcg ttcctaactc aacaggtgct gctaaagcta tcggtttagt aattcctgaa
    95221 ttgaacggta aattagacgg agctgctcaa cgtgttcctg taccaacagg ttcattaaca
    95281 gaattagtaa cagttcttga aaaagaagta actgttgacg aaatcaatgc agcaatgaaa
    95341 gaagcttcaa acgaatctta cggatacaac acagacgaaa tcgtttcttc agatatcgtt
    95401 ggtatgactt acggttcatt atttgatgct acacaaacta aagtaatgac agttggcgac
    95461 aaacaattag ttaaaactgt tgcttggtac gacaacgaaa tgtcatacac tgcacaatta
    95521 gtacgtactt tagaatactt cgctaactta taagatagac aaacgtacaa gtgtaaatta
    95581 tagacatgta catttaaaag cggggaagca atcgcgcttc ttccgctttt tttgataata
    95641 agtttattca ggaggaaata aaatggctaa gaaaacagtg aaagatatcg atttaaaaga
    95701 caaaaaagtt cttgtccgtg ttgacttcaa cgttcctttg aaagacggcg tgatcactga
    95761 cgacactcgt atcaaagcag cattgccaac aatcaactac gttctagaac aaggcggaaa
    95821 agcaatcctt ttctctcacc ttggacgtgt aaaaacagaa gaagataaag aaggaaaatc
    95881 tttagctcca gttgcaaaac gtctaggcga attattaggt aaagaagtaa cattcgtacc
    95941 tgaaactcgc ggagaacaat tagaagaagc aatccgcaac atgaatgacg gcgacgttgt
    96001 cgtattcgaa aatacacgat ttgaagatat tgacggtaaa aaagaaagca aaaatgatac
    96061 agaactaggt aaatactggg cttcattagg cgatgtattt gttaacgatg ctttcggtac
    96121 agctcaccgt gcacatgctt ctaacgtagg tatcgcttca actggtatcc caacagttgc
    96181 tggattcttg atggaaaaag aaatcaagtt catcggtgaa gcagtagaag aaccaaaacg
    96241 accaatgatt gcaatccttg gtggcgcaaa agtttctgat aaaatcggcg taatcgaaaa
    96301 cttgattcct aaagcagata aaatcttgat cggtggcgga atgacttaca cattctacga
    96361 agcaaaagga atcaagatcg gtaactctct agtagaagct gataaagtgg aactagcaaa
    96421 agaattaatc gaaaaagcag gcgacaaact tgtcttgcca atcgacaatg tctgtgcacc
    96481 agaattttca aatgatgttg aaacacaagt aatcgaagga gacattcctg atggtttgat
    96541 ggctttagac atcggcccag catcagtaaa attatttgct gatacattac aaggtgcaaa
    96601 aacagttgtt tggaacggac ctatgggtgt atttgaaatg agtaactttg ctaaaggtac
    96661 aatcggtgtt tgtgaagcaa tcgctaactt agaaggcgca acaacaatca tcggtggcgg
    96721 agactcagcc gcagcagcag aacaattagg atttgctgac aaattcacac acatctcaac
    96781 aggtggcggc gcaagcttgg aattgcttga aggtaaagaa ttaccaggac tagcagcaat
    96841 caacgataaa taaacgacca agtttgctca attctgacga gtaatcgaac aaaaggtgaa
    96901 gggagttttc atgactccct agccattttt caataaatta aggagtgtgt tcctcaatgc
    96961 gtaaacctat tatcgcaggt aactggaaaa tgaacaaaac tgcatcagaa gcaaaagaat
    97021 ttgctgaagc agtaaaaaac aaaatccctt caaatgacaa agttgattca gtcatcggat
    97081 ctcctgcatt attcttacaa gaattaatga catcagctga aggtacagaa ctaaaaatct
    97141 cagcacaaaa ctgctactgg gaaaactcag gtgcgttcac tggtgaaact tcaccagcag
    97201 ctcttgctga tctaggtgtt cattatgtga tcatcggaca ttcagaacgt cgtgaatatt
    97261 tccatgaaac agacgaagac atcaataaaa aagcgaaagc tatctttgca aatggtatga
    97321 caccaatcct atgctgtggc gaatctttag aaacctatga agcaggcaaa actgctgaat
    97381 ggatcgaagg acaaattaca gctggtttag ctgatctttc agctgaacag gtgtcaaaca
    97441 tggttattgc ttatgaacca atctgggcaa tcggtactgg taaatcagct gacgcacaaa
    97501 tcgctgacga aatttgtgga gttgtacgtc aaacagttga aaaactttat ggaaaagaag
    97561 tatcagaagc agttcgtatc caatacggcg gttctgtaaa accagaaaat attgctgaat
    97621 acatggcaaa agaaaatgtt gacggtgctt tagtcggtgg cgcaagcttg caagcagatt
    97681 cattcttgtc attgttagac gctgtaaaat aattgttgaa aatttgcgaa aaatgcaaga
    97741 aatgtttgca ctaatgagca aaattaacta aaatcgtata tgagggaaat cccttaggaa
    97801 aaaacaaact caaaggagag acaaaacatg tcaattatta ctgatgttta cgctcgcgag
    97861 atcttagact cacgtggtaa cccaacaatc gaagtagaag tatacacaga aagcggagct
    97921 tttggccgcg gaatggttcc ttcaggtgct tcaactggtg aatacgaagc agttgaatta
    97981 cgtgacggag acaaagctcg ttatggcggt aaaggtgtaa ctaaagctgt cgacaacgta
    98041 aacaacatca ttgctgaagc aatcattggc tacgatgttc gtgaccaaat ggctatcgac
    98101 aaagctatga tcgctttaga cggaactcct aacaaaggta aattaggtgc gaacgctatt
    98161 ttaggtgttt ctatcgctgt tgcacgtgca gctgctgact acctagaagt acctttatac
    98221 cactacctag gcggattcaa cacaaaagta ttgccaacac caatgatgaa catcatcaac
    98281 ggcggatcac atgctgataa ctcaatcgac ttccaagaat tcatgatcat gcctgttggc
    98341 gctccaacat tcaaagaagc tctacgtatg ggtgctgaag tattccacgc attagcttca
    98401 atcttgaaag ctcgcggatt agcaacttct gttggtgacg aaggtggatt tgctccaaac
    98461 cttggttcaa acgaagaagg ttttgaagta atcatcgaag caatcgaaaa agctggctat
    98521 gtacctggta aagacgttgt tcttgctatg gatgctgctt cttcagaatt ctacgacaaa
    98581 gaaaaaggtg tttacgtact agctgattca ggcgaaggcg aaaaaacaac tgacgaaatg
    98641 atcaaattct acgaagaatt agtttctaaa tatccaatca tctcaatcga agacggatta
    98701 gacgaaaacg actgggacgg attcaagaaa ttaactgacg tattaggcga caaagttcaa
    98761 ttagttggtg acgacttgtt cgtaacaaac actcaaaaat tatctgaagg tatcgaaaaa
    98821 ggaattgcta actcaatcct tatcaaagtg aaccaaatcg gtacattaac agaaactttc
    98881 gaagctatcg aaatggctaa agaagctggc tacacagcag ttgtatctca ccgttctggt
    98941 gaaacagaag attcaacaat ctctgatatc gctgttgcaa caaacgctgg ccaaatcaaa
    99001 actggttctc tatcacgtac tgaccgtatt gctaaataca accaattact acgtatcgaa
    99061 gaccaacttg gtgaagttgc agaatacaaa ggtttgaaat ctttctacaa cttaaaaaac
    99121 aaataattct tttctaatga agatacatga tcgactattg aaagatagtc gagtatgatc
    99181 acttagttaa gtaatcgaac tctctacttg ctgaaatatc agcaggtaga gagttttttt
    99241 gcaactagct tctgtatatg atgtttacaa agaatggtac aagaaaagat catccttgaa
    99301 aaaggaaagc taacaataac tagcatcata taagagcttt taaggataga acagtagaat
    99361 aggaatctat gagcaagtcc tctcgtataa ataaaatagg agggaagtag cagcatattt
    99421 ttcataaagt ggctctcttt cttcattttt actttggttg ctcctatttg aaaattcgag
    99481 cacactcaaa tacaataaaa agaaatggca agggagagga ttagatgaaa aaagaagaaa
    99541 aaatcgcgat tttacaagag atcatccgaa ttaaatcagt gaatggaaac gaaggtgaag
    99601 tagcagccta tttgaataag cttttggcaa agcatgacat aacaggagag attgtttctt
    99661 acagagatgg tagagataat ttgattgctc gttaccaaaa gggccaatca ggaaaagtgt
    99721 taggcctatc tgggcatatg gatgtcgtgg cggctggtga tgaatcgtct tggacctatg
    99781 caccctttgc agcagaaatc catgggaacc gtttgtacgg acgtggtgct acagatatga
    99841 agagtggctt ggcagcaatg gtgattgcca tgatcgaact gaaagagtca ggaaaaccat
    99901 ttaacggaac agtcaaatta ttagccactg tcggagaaga agtgggtgaa ctaggtgggg
    99961 aacagctcac gaaagcaggc tatgtagatg acttagatgc cttgatcatc ggagagccaa
   100021 ccaattacag tttgatgtat acgcacatgg gatcaatcaa ctatacagtc acctcgcacg
   100081 gaaaagaagc gcatagctct atgccagacc aaggttataa tgcaatcaat cacctaaatg
   100141 aattcattac gaaagcaaat gctgaaatga atcacctcgc tgaaacaatc gagaatcctg
   100201 tcctaggaaa aacaatccat aatgttacat tgatcagtgg cgggaatcaa gtcaacagca
   100261 tcccaagcca tgcgcagctc caagggaaca ttcgatcgat tccagaatac ccaaatgata
   100321 aaatcattgc attgctgcaa tcaatcgtca atgaattgaa tcaagagaca gactatcatt
   100381 tggaattgat gatcgattac aacaaaatac ctgtcaaagc tgatccagat tctcctttga
   100441 ttcattgcat tcagcaacaa ttcagccagc cattaccttt agttggagcg gcagcaacaa
   100501 cggatgcagc cgaatttacg aaagctaacc attccttcga ctttgtcgtc tttgggcctg
   100561 gtgtcgttac tttgcctcat caagtagatg agtatgttga aatcgataat tatttggata
   100621 tgatcgaaaa atatcaagga attattttat cctacttagc gtaagatttt tttaataaat
   100681 gaaaaaacag agccagatta gcatta
//
LOCUS       DAMEEU010000003        79830 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.003, whole genome shotgun sequence.
ACCESSION   DAMEEU010000003 DAMEEU010000000
VERSION     DAMEEU010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 79830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79830
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.003"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            42..674
                     /locus_tag="PB779_000214"
     CDS             42..674
                     /locus_tag="PB779_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737766.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(808..933)
                     /locus_tag="PB779_000215"
     CDS             complement(808..933)
                     /locus_tag="PB779_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0737767.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(1067..1960)
                     /locus_tag="PB779_000216"
     CDS             complement(1067..1960)
                     /locus_tag="PB779_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HDE0737768.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            complement(2142..3068)
                     /locus_tag="PB779_000217"
     CDS             complement(2142..3068)
                     /locus_tag="PB779_000217"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HDE0737769.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            complement(3153..3914)
                     /gene="pflA"
                     /locus_tag="PB779_000218"
     CDS             complement(3153..3914)
                     /gene="pflA"
                     /locus_tag="PB779_000218"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HDE0737770.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            complement(4158..6389)
                     /gene="pflB"
                     /locus_tag="PB779_000219"
     CDS             complement(4158..6389)
                     /gene="pflB"
                     /locus_tag="PB779_000219"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HDE0737771.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            complement(6666..9116)
                     /gene="parC"
                     /locus_tag="PB779_000220"
     CDS             complement(6666..9116)
                     /gene="parC"
                     /locus_tag="PB779_000220"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HDE0737772.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDISIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            complement(9128..11173)
                     /gene="parE"
                     /locus_tag="PB779_000221"
     CDS             complement(9128..11173)
                     /gene="parE"
                     /locus_tag="PB779_000221"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HDE0737773.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            complement(11339..11773)
                     /locus_tag="PB779_000222"
     CDS             complement(11339..11773)
                     /locus_tag="PB779_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HDE0737774.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            11900..12538
                     /gene="plsY"
                     /locus_tag="PB779_000223"
     CDS             11900..12538
                     /gene="plsY"
                     /locus_tag="PB779_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HDE0737775.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            complement(12670..13545)
                     /locus_tag="PB779_000224"
     CDS             complement(12670..13545)
                     /locus_tag="PB779_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HDE0737776.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
     gene            complement(13627..14418)
                     /gene="codY"
                     /locus_tag="PB779_000225"
     CDS             complement(13627..14418)
                     /gene="codY"
                     /locus_tag="PB779_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HDE0737777.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            complement(14436..15836)
                     /gene="hslU"
                     /locus_tag="PB779_000226"
     CDS             complement(14436..15836)
                     /gene="hslU"
                     /locus_tag="PB779_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HDE0737778.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            complement(15850..16398)
                     /gene="hslV"
                     /locus_tag="PB779_000227"
     CDS             complement(15850..16398)
                     /gene="hslV"
                     /locus_tag="PB779_000227"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HDE0737779.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            complement(16435..17340)
                     /gene="xerC"
                     /locus_tag="PB779_000228"
     CDS             complement(16435..17340)
                     /gene="xerC"
                     /locus_tag="PB779_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HDE0737780.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            complement(17538..18914)
                     /gene="trmFO"
                     /locus_tag="PB779_000229"
     CDS             complement(17538..18914)
                     /gene="trmFO"
                     /locus_tag="PB779_000229"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HDE0737781.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMAQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            complement(18883..20961)
                     /gene="topA"
                     /locus_tag="PB779_000230"
     CDS             complement(18883..20961)
                     /gene="topA"
                     /locus_tag="PB779_000230"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HDE0737782.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            complement(21083..21940)
                     /gene="dprA"
                     /locus_tag="PB779_000231"
     CDS             complement(21083..21940)
                     /gene="dprA"
                     /locus_tag="PB779_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HDE0737783.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            complement(21996..22763)
                     /locus_tag="PB779_000232"
     CDS             complement(21996..22763)
                     /locus_tag="PB779_000232"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HDE0737784.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            complement(22756..23616)
                     /gene="ylqF"
                     /locus_tag="PB779_000233"
     CDS             complement(22756..23616)
                     /gene="ylqF"
                     /locus_tag="PB779_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HDE0737785.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            23876..24274
                     /locus_tag="PB779_000234"
     CDS             23876..24274
                     /locus_tag="PB779_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDE0737786.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            24553..25053
                     /locus_tag="PB779_000235"
     CDS             24553..25053
                     /locus_tag="PB779_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDE0737787.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(25136..25687)
                     /gene="lepB"
                     /locus_tag="PB779_000236"
     CDS             complement(25136..25687)
                     /gene="lepB"
                     /locus_tag="PB779_000236"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDE0737788.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(25839..26066)
                     /locus_tag="PB779_000237"
     CDS             complement(25839..26066)
                     /locus_tag="PB779_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HDE0737789.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            complement(26063..26581)
                     /gene="msrA"
                     /locus_tag="PB779_000238"
     CDS             complement(26063..26581)
                     /gene="msrA"
                     /locus_tag="PB779_000238"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDE0737790.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            complement(26601..27314)
                     /locus_tag="PB779_000239"
     CDS             complement(26601..27314)
                     /locus_tag="PB779_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HDE0737791.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            complement(27317..28213)
                     /locus_tag="PB779_000240"
     CDS             complement(27317..28213)
                     /locus_tag="PB779_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDE0737792.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            complement(28371..29213)
                     /locus_tag="PB779_000241"
     CDS             complement(28371..29213)
                     /locus_tag="PB779_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDE0737793.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            29345..29998
                     /locus_tag="PB779_000242"
     CDS             29345..29998
                     /locus_tag="PB779_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HDE0737794.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            complement(30061..30588)
                     /locus_tag="PB779_000243"
     CDS             complement(30061..30588)
                     /locus_tag="PB779_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDE0737795.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(30608..31555)
                     /locus_tag="PB779_000244"
     CDS             complement(30608..31555)
                     /locus_tag="PB779_000244"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HDE0737796.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            complement(31567..33453)
                     /locus_tag="PB779_000245"
     CDS             complement(31567..33453)
                     /locus_tag="PB779_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDE0737797.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            complement(33613..35691)
                     /locus_tag="PB779_000246"
     CDS             complement(33613..35691)
                     /locus_tag="PB779_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HDE0737798.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            complement(35704..35979)
                     /locus_tag="PB779_000247"
     CDS             complement(35704..35979)
                     /locus_tag="PB779_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737799.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            complement(36341..36796)
                     /locus_tag="PB779_000248"
     CDS             complement(36341..36796)
                     /locus_tag="PB779_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737800.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(36950..38158)
                     /locus_tag="PB779_000249"
     CDS             complement(36950..38158)
                     /locus_tag="PB779_000249"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HDE0737801.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIKDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(38270..38602)
                     /locus_tag="PB779_000250"
     CDS             complement(38270..38602)
                     /locus_tag="PB779_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDE0737802.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            38750..39625
                     /locus_tag="PB779_000251"
     CDS             38750..39625
                     /locus_tag="PB779_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDE0737803.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(39707..40288)
                     /locus_tag="PB779_000252"
     CDS             complement(39707..40288)
                     /locus_tag="PB779_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HDE0737804.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(40294..41553)
                     /locus_tag="PB779_000253"
     CDS             complement(40294..41553)
                     /locus_tag="PB779_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDE0737805.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(41555..42601)
                     /locus_tag="PB779_000254"
     CDS             complement(41555..42601)
                     /locus_tag="PB779_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737806.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
     gene            complement(42836..43111)
                     /locus_tag="PB779_000255"
     CDS             complement(42836..43111)
                     /locus_tag="PB779_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HDE0737807.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(43354..44664)
                     /gene="der"
                     /locus_tag="PB779_000256"
     CDS             complement(43354..44664)
                     /gene="der"
                     /locus_tag="PB779_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HDE0737808.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(44846..46075)
                     /gene="rpsA"
                     /locus_tag="PB779_000257"
     CDS             complement(44846..46075)
                     /gene="rpsA"
                     /locus_tag="PB779_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HDE0737809.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(46210..46890)
                     /locus_tag="PB779_000258"
     CDS             complement(46210..46890)
                     /locus_tag="PB779_000258"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HDE0737810.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(46939..47574)
                     /locus_tag="PB779_000259"
     CDS             complement(46939..47574)
                     /locus_tag="PB779_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDE0737811.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(47640..49043)
                     /locus_tag="PB779_000260"
     CDS             complement(47640..49043)
                     /locus_tag="PB779_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HDE0737812.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATEQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWGTILLNLFKKNMEH"
     gene            complement(49030..50061)
                     /locus_tag="PB779_000261"
     CDS             complement(49030..50061)
                     /locus_tag="PB779_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0737813.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESAVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            50092..50313
                     /locus_tag="PB779_000262"
     CDS             50092..50313
                     /locus_tag="PB779_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HDE0737814.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(50478..51215)
                     /locus_tag="PB779_000263"
     CDS             complement(50478..51215)
                     /locus_tag="PB779_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HDE0737815.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(51368..52708)
                     /locus_tag="PB779_000264"
     CDS             complement(51368..52708)
                     /locus_tag="PB779_000264"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HDE0737816.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(52945..54468)
                     /locus_tag="PB779_000265"
     CDS             complement(52945..54468)
                     /locus_tag="PB779_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HDE0737817.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(54846..55457)
                     /locus_tag="PB779_000266"
     CDS             complement(54846..55457)
                     /locus_tag="PB779_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDE0737818.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(55580..55705)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(55787..56503)
                     /locus_tag="PB779_000267"
     CDS             complement(55787..56503)
                     /locus_tag="PB779_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDE0737819.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(56509..57078)
                     /gene="scpB"
                     /locus_tag="PB779_000268"
     CDS             complement(56509..57078)
                     /gene="scpB"
                     /locus_tag="PB779_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HDE0737820.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(57062..57859)
                     /locus_tag="PB779_000269"
     CDS             complement(57062..57859)
                     /locus_tag="PB779_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HDE0737821.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFVTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(57829..58200)
                     /locus_tag="PB779_000270"
     CDS             complement(57829..58200)
                     /locus_tag="PB779_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDE0737822.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(58219..59106)
                     /gene="xerD"
                     /locus_tag="PB779_000271"
     CDS             complement(58219..59106)
                     /gene="xerD"
                     /locus_tag="PB779_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HDE0737823.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
     gene            complement(59202..59675)
                     /locus_tag="PB779_000272"
     CDS             complement(59202..59675)
                     /locus_tag="PB779_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDE0737824.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKEKRNQSV"
     gene            complement(59780..60643)
                     /locus_tag="PB779_000273"
     CDS             complement(59780..60643)
                     /locus_tag="PB779_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDE0737825.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            complement(60839..62938)
                     /locus_tag="PB779_000274"
     CDS             complement(60839..62938)
                     /locus_tag="PB779_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDE0737826.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            complement(63158..64267)
                     /gene="rpoD"
                     /locus_tag="PB779_000275"
     CDS             complement(63158..64267)
                     /gene="rpoD"
                     /locus_tag="PB779_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HDE0737827.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVALLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            complement(64291..66132)
                     /locus_tag="PB779_000276"
     CDS             complement(64291..66132)
                     /locus_tag="PB779_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HDE0737828.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            complement(66314..68629)
                     /locus_tag="PB779_000277"
     CDS             complement(66314..68629)
                     /locus_tag="PB779_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDE0737829.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            complement(68814..69674)
                     /locus_tag="PB779_000278"
     CDS             complement(68814..69674)
                     /locus_tag="PB779_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HDE0737830.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            complement(69733..70254)
                     /locus_tag="PB779_000279"
     CDS             complement(69733..70254)
                     /locus_tag="PB779_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HDE0737831.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            70532..71293
                     /locus_tag="PB779_000280"
     CDS             70532..71293
                     /locus_tag="PB779_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0737832.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            71319..73910
                     /gene="mprF"
                     /locus_tag="PB779_000281"
     CDS             71319..73910
                     /gene="mprF"
                     /locus_tag="PB779_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDE0737833.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(74098..75285)
                     /gene="tuf"
                     /locus_tag="PB779_000282"
     CDS             complement(74098..75285)
                     /gene="tuf"
                     /locus_tag="PB779_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDE0737834.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            75653..76009
                     /locus_tag="PB779_000283"
     CDS             75653..76009
                     /locus_tag="PB779_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDE0737835.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            complement(76250..77254)
                     /locus_tag="PB779_000284"
     CDS             complement(76250..77254)
                     /locus_tag="PB779_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HDE0737836.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            77420..78271
                     /locus_tag="PB779_000285"
     CDS             77420..78271
                     /locus_tag="PB779_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDE0737837.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            78288..78533
                     /locus_tag="PB779_000286"
     CDS             78288..78533
                     /locus_tag="PB779_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737838.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            78720..79424
                     /locus_tag="PB779_000287"
     CDS             78720..79424
                     /locus_tag="PB779_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737839.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
BASE COUNT        21981 a        16759 c        13705 g        27385 t
ORIGIN      
        1 tattatactt tatatactta tcaatttaat ttggagatat tatggaaatt caacgtagaa
       61 ccactaattt tttacattta ggctcttttt ttgcaacttt gacgatctta ttttttctat
      121 gttattcata ccttaagacc tcacatgcgc cttctagtgc attaggctgg ttgcttttgg
      181 atcattctga tatcacagaa gccgaagaaa atccgttttt tttgattttg tcttctcttt
      241 gcggcttact gttttctgtt tatttcggtg cctatttttt tcatcgacat cctggtacgt
      301 taaacgaagc ttcaagcgta ttgattgcat ttaaaacgtt ttctttttta gcaattcttt
      361 tttattcgtt taatcacaat acgcttttct tctttatcat gaatggttta gtcgtgattt
      421 tatccatttt tacttatttt attttttcac tcatttttag ccaattgaaa tgtccgctct
      481 tctttcgatt agttcctgtc acctgtttta tttacagctt gttttccttt tttgtccttg
      541 ctttaatgcc actgaccaac ccttcgacga tccaagtcgc aggaaatctg ttggatatgc
      601 tcttcatcgt cagtctaggt gtatttatgt ggcaaagaaa aaacaaacaa aataaaaagc
      661 attttgaagc ctgactatta cgacttcata aatgcttttt tagttttaaa cacttcaatc
      721 taaaagaata acccaagatt ggataaatta ttaatgactc gccattcgtt tcttagtgat
      781 tctggattat caaatggact tcctaatcta atcagctagt tcttcccata aaatgccata
      841 cttgactgaa tcataatatt gattatttaa aaatctaact tttcttatca ctacttcctt
      901 tgtcattcca catttctcac catttttttg cattcctttg tttccagacc atgtagtgaa
      961 tctaataggt ggtagatagg caaaatactc aaataattct tttaaccata aaggaagaga
     1021 aaggctcctc ctgcaagagt cagtataatt tttgcttact gctctcttag gttttactca
     1081 ctaaaactgt tccatattct ttgatataag aaaatgcatg cggtataaat ttcttgctca
     1141 gctcagaaaa gatttgtcgt ttaagaaagg ccatttcctc cattgtcaat gaaggatcca
     1201 atgttggtaa ttcaatctca aaattgtttt tttcgacaat aggtaattct aatgtgaatg
     1261 attcttcttc ctttatagta ttcgtcacaa gtagagactg atggaaaata ctaggccggc
     1321 gatttttata tttattctta cgtatcctgt caacgataac ttctatttga tcaaaaaagt
     1381 acgattcatt tacgtctcca ataagttcgg ctaattcttt gaatgccttc gttacaggaa
     1441 gctgattctt ctgtacaaaa aagtaattag ccaaagtaag cgggaagtgt tctatagagg
     1501 aaagtgtgat aaaacggtac ttctcatttc ctgcagttgt cctcagcaat tctgtctctc
     1561 ggctgtttct tactccataa aaatacgctt ctttccgttc atcttcgaaa caatacgccc
     1621 aaataacttc tcccatcgct aatttttgtt catcaacaga gagtctcttc aattgttcag
     1681 ctatggtttc agcagccgaa gtggcttgtt gcaagtaatc tttaggatca aatattggaa
     1741 agttcaaatg atatcttcgt tcttccctct tgattaatcc tgcatcgatc aataaatcaa
     1801 gaaaatggga aaatttattt tgcgaaaatt cttttttcaa ttctcttaga atcgtttctt
     1861 gttctcgatg ttcatataga taatcggtca atgaagaaaa aagcggatca tcggtcagtt
     1921 tttgataaaa gttttcctta ttttttgaat aatagttcat atatgttctc ttttctatcc
     1981 gttttatttt acttaaaagg cttttacgta aaaaggagga agaacaagag tcataattga
     2041 ctgttattct cctccatttc ttcggccttt agtatgttct atgtttcttt ttatatcaat
     2101 cgcttatcca ttcattttga atgcttcata ctaccatttg attagctaaa tacagccgtc
     2161 aattgaggta cgacttgttt tttacgtgaa acgacacctt taagcaaagc acggttgttg
     2221 gtcaaagttg tttggaaagc ttcttctact ttttcttttc ctttaccagc aacaagtaat
     2281 tctgaatcac tgtctaagat gtttgtgaca actaatacga acagatcgta gccatttgct
     2341 ttcatttcat cttccattgc tgcttctagc tctgcttgtc gatccatcac ttcattaagg
     2401 tccactgtat tgacttgagc gatacgaacg ttggaactgc ccattgggaa actttttgca
     2461 tccaaatcaa gaagaaccgc agctgattta tcacttagat ttgttcctgc tttcaacatt
     2521 tcaagtccat aagtgtttag atcgacttca gcgattgctg caagttcttt tgcagctgct
     2581 tcatcttcag gcgtacatgt tggtgatttg aacaacaatg tatctgaaat gatagctgag
     2641 agcatgattc ctgcgatttc tttaggaatt gttacttggt tttctttata tagttttaaa
     2701 ataatcgtac ttgtacatcc aactggttct gcacgatagt acaatggatt agctgtttca
     2761 aagtttgcaa tacgatggtg gtctactaca gctaaaatat ttacttcgct gatatctgaa
     2821 atactttgtt ggaattcatt atgatccaca agcatgacat ctgcattttc tgctttagct
     2881 gactctacta ctcgtggtgc agatagctga aagtggtcta atgcgtattg tgtttcttca
     2941 ttaggtgtac ctagagcaac tgcttctgtt tctttaccta attcattttg caagtgtgaa
     3001 aacgcaatgg ctgccccgat tgcatctgta tctggatttt ggtgaccaaa aactaaaatt
     3061 tttgacatgt cattcgctcc tttgtgattt ctcctattta ataatagcaa aaaaacggaa
     3121 agaagcaata cttatcttct ttccgatgcg acctatcgcg ttaaatattt tgtatactct
     3181 tctgtatgaa gcaatcgttt agcattttcg acacgttctt ttgtaggtgg ttcgatccct
     3241 tctaatggat atttcaaacc aagtgtttcc cacttgtatt ttcccatcgt atgataagga
     3301 agaatctcta ctctgtctac atttgacaag gtttgaataa agttgtctag tcggatcaaa
     3361 tattcatcat aatcacttcg ctcaggaact agtacatggc gaatccaaac cggtttgttg
     3421 atttttgaca aatattgagc catttctaaa atattttcat tgtcccaatg cgttagtttt
     3481 ttatgctctt cattatcgat gtgtttgatg tcaaataaca gtaaatctgt atacttcatc
     3541 aattcttgaa aacgtgaaaa gaaaggttct tcatacgtaa aaggttttcc gcatgtatcc
     3601 aatgtagtat gcatcttccg ctcttttgct tttttaaata gttcgatcaa aaaatcgatc
     3661 tgcaatagag gttctccacc actaacagta ataccacctt tatctcccca gtaaggtctg
     3721 aagcgttctg ctttatctaa aagttcatct gctgtgtatt ctttccctcc gccaatattc
     3781 caagtatctg gattgtgaca aaattggcaa cgcatgcggc atccttgcat aaacacgaca
     3841 aagcgcagtc caggtccgtc tactgaaccg aaagtttcga tagaatgaac atagccgatt
     3901 gttttttctt ccatttaagt tcacatcttt tctttgattt cattttaagt acaagttagc
     3961 tgtcgaagcg aagctttctg aacaaaattt ttcgcaattg ccgcttcgtt atgtgtaaaa
     4021 tttacaggga cggaacatac aagtcctgcc cctgtaaatc gtttctttca aataagcata
     4081 ctgattattc gattttgatg cgatggctat tcaacgtcct ttcgacgcta agtcgaaaaa
     4141 cttttttcac gaacttttta cattctgtcg tgtgaagttc tcatcaagac atctaattgt
     4201 tgttctcttg tcaagtcacg gaatttaact gcataaccag atacccggat cgtcaagttc
     4261 ggatatttca ttggattttc cattgcatca cgcaataaat cattactgaa tacattgaca
     4321 ttcaaatgat aagctccttt tgagaagtat ccatctaaga cattacgcaa gttttcgatt
     4381 cttgtatctt gttcttttcc aagacctgaa ggattgattg tttgggtatt tgaaattcca
     4441 tccaatgcac agccgtaatt cattttagct gttgagttca ggctagctaa taacccactt
     4501 tgttccgcat tgtaacttgg atttgctcct ggcgcaagtg gttttccagc ttcacggcca
     4561 tcaggagtat ttcctgtatt tttaccgtaa acaacatttg aagtaatcgt caataatgaa
     4621 gttgttggtt ttgagttgcg gtaagtttta tgacgtttga tttgtcccat gaagtattcc
     4681 aagatccatg aaactaattc atctgcacgg tcatcatcat ttccgtattt agggaagtcg
     4741 ccatccactt caaaatcaac tgctattcct ttttcattac ggattgcttt tacttttgca
     4801 tatttgatcg ctgacaagct gtctgccgca tgagagatcc cagcaatacc tgtagcaaat
     4861 gtgcgttgca agtcagaatc catcaaagcc agctgagctg cttcataaga atatttatca
     4921 tgcatataat gaatgatgtt caacgtattg acatatagtt ctgctaacca atccatcata
     4981 ttcatgaagt tatgtttcac ttcttcaaag tctagtattt ctgatgtgat tggacgatat
     5041 tctggtccaa cttgggcgcc agtcacttca tcgactccgc cattgatggc atataatagt
     5101 gttttagcca agttagcacg agcgccaaag aattgcatgt cttttccgac aactgttcct
     5161 gatacacagc aagcaatcgc acaatcatca gaaccccatt gttcacgaag ctgattatca
     5221 ttttcgaatt gaatcgaaga actttcgata gcgattctgc tagcatatgt tctgaatcct
     5281 tctggaaggt gttcagaata caaaacagtc aagtttggtt ctggtgaagg tcccatattt
     5341 gttaatgtat gaagcagacg gaaatcattc tttgtaacta atgaacgacc atctaatccc
     5401 atacctgcaa tggataaagt agcccagata gggaatcctg agaataattg gttatattca
     5461 ggtgtacgcg cgaatttgac catacgtaat ttcattacta agtggtcgat caattcttgt
     5521 gcttcttttt ctgtgattac tccattatcc aaatcacgtt ggatatagat atcaaggaat
     5581 gctgagatac gtccgattga catcgcagca ccattttgtg atttgattgc tgctaaatat
     5641 ccgaagtata gccattggac agcttctttt gcatttgcag ctggtttaga aatatcatag
     5701 ccatatttcg cagccatttc tttcatttgc gctaatgcac gatattgttc agtgatttct
     5761 tcacgtaaac gaatcacttc ttcactcatt gtatgataac cagtcatatc atgatctttt
     5821 ttcttttgtt ccatcaaata gtcgattcca tacaatgcca cacgacgata gtcaccgatg
     5881 atacgtccgc gaccgtaagc gtctggaagc cctgtaatga ttttgttttt acgagcagca
     5941 cgcatttcag cagtataagc gtcaaataca ccttgattat gtgttttgcg ccagtcagtg
     6001 aaaatatgtg tcaattcatc gtttggtgta tagccattgc tttttagcgc attgttagcc
     6061 atattgattc cgccgaacgg catgaatgct tgtttcaaag gtttgtctgt ctgtagaccg
     6121 acgatttttt ccaaatcttt atccaaatag cctgcatcgt gtgaagtaat agttgatacg
     6181 atttctgtgt ccatatcata gacaccgtta cgctcgaatt ggatatcatt taacttttgc
     6241 aattcatccc ataatttttc tgttgcttct gttgggcctt ccaaaaagct gtcatcaccg
     6301 cgatattcag tgtagttatt ttgaataaag tctctagtgt ctacgccttc tttccatttg
     6361 gtacctttaa atccattcca ttgctccatt gtatggacct cctaaatttc tgttttatgt
     6421 aacagttttt acgtgattag tataacacag caccctatct ttgcaagggt tttcttgttt
     6481 tttatttaac aatttttatg ttttatttac atatatttaa atcaacgttg acataccaac
     6541 atttaagcat tgtgaacact ttcatctttt tttgcaaacg tataaggatt tattaaaaat
     6601 gaatgaaaaa gagacgccac ctgtattaat acagatggcg tctcttcatt aaaatactac
     6661 aacagttacg actcgatgaa aatctcagga gcatcgataa cttcgatgac ttctccacct
     6721 tttttctcat ccatcgcaaa tgatccattc gatgttcgat cacctatagg gaaatcagtt
     6781 gggtcaatcg ttaactgctg ccctttttga ttcatcaagg ttatttcttt tgatcttcct
     6841 tccgacatat agataatacg gtgcggattt tttttcagct cacgcatgac cgtcactccc
     6901 cgcttcgcac gtgaagtttg gctgatttct tgagcaagca tgcgtttaac agctcctcgc
     6961 tgagtaacga ttacgatcgg cgtatcacct tctgctaaca caagcagccc gttgataatc
     7021 ctatctccat ctttcaaatt catagacttc actccagctg cctttgctcc aacaacggga
     7081 acatctgtta aaggatagcg caaacccatt ccttgatgcg ttactaagaa aacatctaag
     7141 cctggctgat cttctttcag atacacagca atcagttcat cttcttccgc ctttagcttc
     7201 atacagctga gcggacggct cttataggtg cgccatggtt cgaactctgt cattcgtgtt
     7261 tgcttgatca atccattctt gctgatgaat acaaatgttt tctctgcttg aattttttga
     7321 tatgggaaaa cagctaaaat cgattcgtct acagacagat tggagattgt ttgagaaatg
     7381 tgctcaccag catctttcca tttcaaatcg ggtagttcat ggacagggcg gtagatcaca
     7441 tttgctttat ttgtgatcag aagaacatgg tccaatgtac tcaattcacc tgagtatagc
     7501 aagtagtcgc cttctcgcat cccgatttct tctggtttgg aagcactata agaacgaagg
     7561 cttgttcgct tcacatagcc ttctcgcgtc acactgacaa ttacgtcttc ttgtgccact
     7621 aagacttgcg tatcaatttt gatttcttcg atttcgtctt cgattgtcgt tagacgagcg
     7681 gaagaataat tttttttcac ttctcgcaat tcttttttca taacagagaa aagctctttg
     7741 tcatttgaaa ggattttatt caactctgtg atttgcgcaa tcaagctttc ggattccttt
     7801 tgaagctctg tgatatccgt gttcgtcaaa cggtataatt gcaatgtgac aattgcttct
     7861 gcttgttctt ctgtaaattg aaagacgtcg actaaattct ttttggcgtc ttttttgtct
     7921 ttactttcac gaatcgttgc gattacttca tccagaatcg ataaagcttt catcaatcct
     7981 tctacgatat gctgtctttt ttgagctttg gctaaatcga attgactacg ttttgttatg
     8041 acttgctttc gatgctcgat ataacttctt aaaatgtctt tcagtccaac ttgatgcgga
     8101 gtcatatggt cgatagcgac catattgaaa ttgtaattga tctgtagctc agtgtttttg
     8161 aacaaataat tcaaaattcc ttgagcattg gcgtcttttt tcaattcgac gacaatttgc
     8221 agacctgttc tatcactttc atctcgtact tcagctattc catcgatttt cttattcaaa
     8281 cggatctcat ccattttttt caccaaggtc gctttattta cttcatatgg gatttctgtg
     8341 atcacgattt gctgtttatt acccttcatt gcctctatct ttgttttcga acgaagaata
     8401 acttttcctc gtcctgtttc ataagctttt ttgatttcat cttttccttg caagatccct
     8461 cctgttggaa agtcaggtcc aggaatatat tccatcaatt tttcaaggct cgcttgtgga
     8521 tgatcgatca tatagattgt gccatcgatc acttcagcta agttatgagt cgggatttct
     8581 gttgcatatc cagcagatat acctgtcgat ccattgacga gaaggtttgg gtatcgagct
     8641 ggaaggactg ttggttcttt ttctgtatca tcaaaattcc acacgagatc gactgtttct
     8701 ttctcgatat ctgctagcat ctctccactt aacttggata atctggcttc agtataacgc
     8761 atcgcagcag gtggatcacc gtccatactc ccgttattcc cgtgcatttc gatcagtact
     8821 tcccgcaact tccagtcttg gctcatgcgg accatcgctt cataaatact gatgtcacca
     8881 tgaggatgat aattccccat gatatttccg acagattttg ctgatttacg gaatcctttg
     8941 tcatacgtat tgccatcttt gttcatggca aataatatcc ggcgttgcac tggcttcaat
     9001 ccatcacgga tatcaggcag tgcacgttct tggataatat atttggaata acgtccgaag
     9061 cggtcaccca tcacttcttc taaagttaat tcttgtactt cttgtcgatt ttccatcagg
     9121 tgacctccta ttctacttca aataactgat tgttttcatt tttatctgct cgttcttcat
     9181 ctaataaatc attagaaact gaaggagaga tttcagtatc ctctttttta tctaagatac
     9241 tgccatcttc ttcgagcgta aattgcacgt gattttcgat ccattttctt cgaggttcta
     9301 ctttgtcacc catcagtgtg gttactcgac gttcagcttg cgcagcatca tcgatacgga
     9361 cgcggatcaa cgtacgggaa gtcggatcca tcgttgtttc ccacaattgt tccgcattca
     9421 tctctccaag tcctttatat cgctgcagca tatatccttt gccgactttt ttaatcattg
     9481 ctgccaattc gtcatctgtc cacgcatatt caatgacttg cttctttcct tgtcctttgg
     9541 atactttata taaaggcggt aacgcgatat atactttccc agcttcaatc agcggtttca
     9601 tataacgata aaagaaagta agcagtaata cttgaatatg ggcgccgtct gtatccgcat
     9661 cggtcatgat gattactttg tcgtaattac agtcttcgat agaaaactca ggaccgactc
     9721 ctgcaccaat cgtatagatc atcgtattga tttcttcatt tttcaagata tcttgcattt
     9781 tagctttttc ggtattgatg acttttcctc gtaaaggtag aattgcttgg aactttctgt
     9841 ctcttccttg tttagcagat ccgccagcag aatccccttc gactaaatac aattcatttt
     9901 tcttagggtt tcgggattgt gcgggtgtca attttcctga aagaagagat tcgccttttt
     9961 tacgcttctt cccatttcgg ctttcttctc tggctttacg tgctgcttct ctcgcttctc
    10021 tggctttgat tgctttacgg accaacatct ggctcatttc gctattttcc tgcaaataaa
    10081 agcccatttg ttcactgatg acgttatcta ctacggtacg agcaactggc gtaccaagtt
    10141 tttcttttgt ttgcccttca aattgcagaa gattttcagg tacacggata gaaagtacag
    10201 cagctaaccc ttctctgaaa tcactacctt ccagattctt gtcccgttct ttcagcaaac
    10261 caacttttct cgcatattca ttataagatt tcgtcatcgc cgctttcata ccagcttcat
    10321 gggttccccc atcttttgtc cgaacgttat tgacaaaaga taaaacattt tctgaataac
    10381 cgtcattgta ttgataagcg acctctactt cgataccttc tttttctcct gaaaaataaa
    10441 caactggtgt caatgtatct ttttcttcat tcagataatc aacaaattct ttgattcctt
    10501 cttcgtaatg aaaaatttcc ttgactggtt cttctccacg aagatcagaa agagagattt
    10561 taacgccttt tagaagaaag gcagattctc ttaaccgttc ggctaaaatt tcatatgaaa
    10621 atttcgttgt actgaatatt gtatcatctg gtaaaaaatg gacagtcgtc ccgtttgctt
    10681 tttttgtttt tcctatcttt ttcaaagtac cgtcaggttt accgccgttt ttaaatttct
    10741 gctgatactc tacgccatct ctaacgatcg ttacaattag ccatttcgat aaggcattta
    10801 ccacactggc tcctacaccg tgcagtccac cagaagtttt gtaccctcct tgaccaaact
    10861 ttccgccagc atgcagcaca gtaaaaatca cttcaactgt tggtattccg gaagcatgca
    10921 ttcctacagg catcccacgt ccgctatctg caacagttat actattgtct tcatggatgg
    10981 tcacatcaat ctcactgcca taacctgata atgcttcgtc aactgcatta tcgacgattt
    11041 catagactaa atgatgcaag cctcggctgt cagtggatcc aatgtacatc cctggtcttt
    11101 ttctaactgc ctctaatcct tccaatactt ggatggacga gtcattgtat tcgttgttta
    11161 ctttttttgc caaggcaaac gctccttcaa taatactttg cggcaaaacc gcaccacgat
    11221 tatcatacta gaaaaggtcg tgaaaaaaaa gagggtagac gagaaatcaa ttttaattat
    11281 ctcctaaccg ctttttcgac attcccctct atcgatcatc tcttctttgt ggtcattttt
    11341 atttttggtt ttctttcaac ttaccaagtt caatcttaat acaacgatcc attacgatat
    11401 ctgtacgtcc tgcttttctt agcatctcag ctgcttcttt gttttcaatc cctaattgtg
    11461 cccagaacac tttagcatca gttttcaaaa aatcacctgc tatttcaggt aaaaattcac
    11521 tccgtctaaa tacatctacg atatcgattg gatcatcgat ttctgtcaaa ttcgcataga
    11581 ctttctcgcc tagaatttct tcaccagcca ataatggatt tactggtatg attttatatc
    11641 cattgtcttg caatacctgt gcaaccatgt aacttgttcg ttctggttta ttgctcaagc
    11701 ctacgacggc aatatttttt gcttcttcca aatagttgaa aatcgtttct tgtgttggat
    11761 tttttacaga catttctgcc accccttgct tttcttttta ttccatctat tatacttgta
    11821 tctttcattt tttcaattgt tcctgttacc tattcatgct aaaataaagg atagttttca
    11881 acttgaaaga gggtaaaaaa tgaaattgat cttattactt attttagcat atcttttagg
    11941 ttctattcct tccggtgtct ggattggcaa attgtttttc aaaaaagata tccgacaaca
    12001 cgggagcggt aatactggaa cgaccaatac atttcgtgta ttaggcaaaa cagccgggat
    12061 tgttgtcctg cttatggata ttttaaaagg tacattggct acttgtttgc cgatgatctt
    12121 ccacctttct gggattaacc ctctttggtt tggggtatgc gccattcttg gccatacatt
    12181 tccgattttt gctgggttca aaggaggaaa agctgttgcg acaagtgcag gaatgctttt
    12241 aggatttaat cctgtatttt ttgtttattc ttgtatcatc tttatcgtta gtttattttg
    12301 tacaagtatg gtgagtttga gcagtatgat cagtgcagta ttgatcactt tatctacgat
    12361 cgtccttcct tatgtagctc ctgtgatttt ggctaagccc aattggttac tgacgatcat
    12421 tgccttttta gtttcttcct ttatctttta tcggcataaa gacaatatca agcgtatcag
    12481 aaaccatact gaaagtcgaa tcccgtttgg tttgaatagc agcaagaaaa aatcctgata
    12541 ctttttcatt ccaaagagat aaaacgggag tgtgacaaat cgatgtcaca ctcccttatt
    12601 acttacagga tagctttttt acacaccttg gtaaacggtg ttccctgcta acttctcggt
    12661 cacaacctct tacttcactg tgatggaata ttttgtcttg aagatttcat gggcacctag
    12721 ttgattgatc cctacttttt ccatcaagtt tccactactg ttcaccgtgt cagcgattcc
    12781 gcaccacggt tcgatacaaa cgaaaggcgc ttcttttgga taaggagacc agatccctac
    12841 ataaggcata tctttatagc ttaaagttac gctatgggaa gatttttcac ttcgaatggc
    12901 gtacgcattt agaccccttg tttcaaaaac caaggcatct tgctcaaaaa gttcacgatt
    12961 caaagccaga ttcgtatttg tctgacctaa cgtcttttga tccatatcga tgaatgggcc
    13021 tttcaatggt aggcgtaatc ttgatttcaa tggagaaaat gccagataga aatcttcaaa
    13081 tgacaatcct tcttcaagag gtacattgaa agcaggatgt ccaccgatag aaaagaacat
    13141 ttctttttca ccggtatttg ccacttgata atgaaccgtg atgccgtctc ctcctaattc
    13201 atagctgatc actaattcaa aatcaaatgg atacttttct aatgtctccg gcgtactcct
    13261 taagatgaaa ctagccattt cttgtccatg ttcaatgact tcaaaatcca tatcccgagc
    13321 aaatccgtgt tgccccattt gatatgtttt cccttgataa acatactgat catcttttaa
    13381 acgtccaaca aaagggaata aaaccggtgc atgtctgccc caatacgctg gatcaccttg
    13441 ccagatatac tctaaaccat gttcttttga tttcagactg atcaattccg caccgtgttc
    13501 agcgatttcg gcgatcagct ggtcattttg aataataaca gtcattgcca ttcctccaac
    13561 ttcgacttac tttttaaaat gggaaggctg gaacaaacat ttctatctgc cccagtcccc
    13621 ttacttctaa taactgtgtt ttgctaactc gtctttaaaa cgggaattca atacttttaa
    13681 ataagttccc ttcatgccta acgaacgaga ttcaatgatt ccagctgatt ccaattttcg
    13741 taaagcattg acgatcacag aacgagtgat gccgatacta tcggcaatat tagaagcagt
    13801 cagacgacct tcatctccat ccaatgcttc aaagatagct tgtacagcct tcaattcgct
    13861 ataagataat gtgttgattg ccatttggac agccgttgca ctccgtacat ctgcttcgat
    13921 gcttcgagac ttctgataaa ggatctgcat accgacaacc gtagctccat attctgctaa
    13981 gactagatcg tcatctgcaa acgattgttc catacgagat aagataatcg tacccaaacg
    14041 ttcgccagct ccaaagatcg gaacgacagt cgtcagacca aatggatatt tctctcttga
    14101 ctctaccgga aatgcagtaa tatcactagt aattgggata ttagcttcag ttttcatcaa
    14161 ctgtgccact gtatcagtat aagattcagg aaattgtttc tcaacaaaca ttgttttgat
    14221 tcgttcattg ttcacatcgt gacgttcatt ataacctagt aatactccgt cacttcctat
    14281 gatataggtg ttgctgtcaa gaataccacc tagtgtgaca gccattttat cgtaaggcaa
    14341 atctgcttgc atgtcaaaag tattcttttg ctgcaaaagt gtgtttatct tgcgggtttt
    14401 cgttagcaag tctgtcattg tcgtcctccg attttttata aaatatagcg acttaaatct
    14461 tcatttgccg caattgagcc aagtttgtca tccacatatg cttctgtgat cgttatttct
    14521 cccatttgca tatctggtgc ttcaaataat agatcttcta gtagtttttc caaaatggta
    14581 tgcagtctgc gtgcgccgat attatctgtg tcacggttga catcgaaagc gatttgagcg
    14641 atccgttcaa ttgcttcttt tgtaaacgta actgacacat tttctgtacc gatcaacgcg
    14701 acgtattgtt ttactaaagc attatttggt tcggtcagaa tcttcacaaa atcttcagct
    14761 gtcaaatcat ctaattctac ccgtatcggg aagcgtcctt gaagttctgg aattagatca
    14821 cttggtttag acaaatggaa agctcctgaa gcaatgaata ggacgtgatc tgtttggatg
    14881 atcccgtatt ttgtgtttac ttgtgaacct tcgacaattg gcaatatgtc tctttggacg
    14941 ccttctctgg atacttctcc agattgctgt gatttagaag tgatcttatc gatttcatcg
    15001 ataaaaataa ttccactttc ttccgctaat ttgattgcct cactatggat atcagcatcc
    15061 ttgactaatt ttgctgattc ttccttgatc aataactcta aagcttcttt gactgttacc
    15121 gtccgttcca cttttttctt cggtgtcaaa gcacctagag tttcatttag gtcgatcccc
    15181 atttgctcca atccattgtt catcattggt gcaggtttct tttggtcttc aacttcaatg
    15241 gttacttcac gactatccag taaacccttt tgtagttgtt ccaagactgt acggcgattg
    15301 attcgaatat cttctgtcac ttcttcttgc ggttcagcgg tattttgctg actagcatta
    15361 aaaagattca tcatttgttc aaattgatta gtggattgtt tctgttcttt tttgatacca
    15421 ggtaccaaga tttttaccaa acgtttttct gcattttttt tagcacttgt gtatacacgg
    15481 ctgtactgct ctttttctac gatttggatc gcattttcta ctaaatcccg aaccattgat
    15541 tctacatctc ttccgacata accgacttca gtaaattttg ttgcttcgac tttgacaaat
    15601 ggtgcattga cgatttttgc caaacgtcgt gcgatttctg ttttaccgac ccctgtaggt
    15661 ccgatcatca gcatattttt tggtgtaata tcttgttgca ttttttcatc taactgcaaa
    15721 cggcgatagc ggttacgcaa agcaacggca acagattttt ttgctgcgtg ctgtcctacg
    15781 atatattcat ctaattcact tacgatttgt cttggtgttt gttttaattc atacatatct
    15841 actcacctct tacagttctt ctacgataat attatgatta gtaaagatac agatatctgc
    15901 ggcaatattt aacgcatttt ctgcaatttc tttcgcactc atgtcgtttt gagcatagtt
    15961 tttcattgct cgggctgcag ccaacgcaaa attccctcct gatccgatag ctaagatacc
    16021 atcatctggt gtgataactt ctcctgtacc tgaaacaaga agcatttctt tatcattcat
    16081 tacgatcagc atcgcttcaa gtttttgcat agattgctgt gtccgccatt cttgagctaa
    16141 ttcgacagct gcgcgttgta gattcccgtt atattcgttt agtttgcctt caaatttttc
    16201 ttctaaagta aacgcatctg caacacttcc ggcgaaacct acaacaactt ctccattgta
    16261 gatacgtcgt actttctttg cagtgccttt catgacaaca gattcaccca ttgttacttg
    16321 gccatctcca gccatagcaa atttcccgtc tttttcgacg gcacagatag tggttgaatg
    16381 aaatggtgat tcgaccatgt ttgtttcctc ctaaatttgt tcttttcctt atttttacgc
    16441 tcttggatgg aaagaacgat agtttttttg taaactttct tttgttacat gggcatagat
    16501 ctgggtagtc gataaattgg catgtcctag caattcttgg actgtccgca aatctgcccc
    16561 attatttaat aaatgagtag caaatgtatg gcgcagcatg tgaggatgga tatcactatc
    16621 caaactgctt tttttgatca tttgattcaa gacatattca attccagtag gcgtgattgg
    16681 ttttccatga tgattcacaa aaacgatatc atgctcttcg tgatattttg tcatcaatac
    16741 ctggcggcct tccctgaaat attcttgcag agcatcttga gcaaaagaac ctagaggagc
    16801 atatctctct ttgttccctt taccatggat caacatgacc tctgaatcaa aatcaatgtc
    16861 tgataccgac aaactgctac actcacttaa acggatgcct gacccgtaaa ggacttccag
    16921 taaagcgcgg ttcctcaaat ccaaaggact atctcctgct acgctgtcaa aaagtgcttg
    16981 catttcattt tcataaaaaa aacgtggcag tctcaaattt ttctttttga gatgaacgta
    17041 agaaaatgga ttttctttta tcacttcttc tttgagaaga tactgataaa acgaacgtag
    17101 gctggctatc ttgcgactga tagaatttct gctatagcta ggacgatgat cagctaatgc
    17161 actcaaatag acacgaaccg taaaatattc cgccttcagc agatcagcgt ctccagattc
    17221 ctccaaaaaa tgtttgaaat ggagaatgtc ttcttcatat gcttctttcg ttttttctga
    17281 atatcctctt tcgacaatca aataacgcaa aaatttttgt tcccacgtgg cttctgtcat
    17341 tttctcacct tccttttgtc ccagagaata atttagcaca gcgtttataa aaagacaaat
    17401 aaattgtcag aatttaacca atatttctaa gtttgttcac aattggcgca attcctcaca
    17461 ttttgtttga gaaattctta agaaaaacgc aagaaaaaga gcgagactat ccgtctcacc
    17521 ctcttcatgg agtttcctta ctcatttggg attgcagttt tttctaattc tgtttttatt
    17581 gcctcattag cttttaaagc tcgttgtgca attgcttcat atcttgcttt tttgtctcga
    17641 atgcgctctg gcagttcagg aaacagacca tagttggcat tcatcggttg gaaatgtttt
    17701 ccttccgcat gagtaatgta gtaagccata cttccaatag ctgtttcttg tggaaactcg
    17761 actggttcca tttcttttgc taagcgtgcg gcgttgattc cagcaagtag tccgctcgct
    17821 gcactttcaa catagccttc tacaccagtc atctgacctg caaagaacag atcttcgcgt
    17881 ttcgttgatt ggtaagtcgg tttcagcaat tctggcgaat tcataaagct gtttcggtgc
    17941 atcacaccat agcgaacgaa ttcagcattt tctaacccag gaatcatccg gaaaacacgt
    18001 ttttgctcgc cccatttcaa gtgagtctga aagcccacga tgttgtataa agaagctgca
    18061 gcattgtctt gacgcagctg gataacagca taaggacgtt tgccagtttt aggatcttcc
    18121 aatccaactg gtttcatagg tccgaaaagc atcgttttga atcctcgctg tgccattact
    18181 tcaattggca tacatccttc aaaatatttt tctttctcaa aagatttaag ttctgccact
    18241 tcggcattga ttagtgcctc atggaaagct ttgaattcct cttctgtcat cggacagttc
    18301 aagtaagctg cttctccttt gtcatagcgg gacttcaaat atactttatc catatcgatc
    18361 gtagctttgt ctacgattgg tgcagctgca tcatagaaat aaaaaccatc tgaaccattg
    18421 aatgctttga tgctttctgc taatggatga gaagtcaaag gtcctgttgc tactacggtg
    18481 attccttccg gtatttcagt aatttcttcg tttatcactg ttactaatgg atgctctttg
    18541 acttttcggg taattgtttc agaaaaagaa tcgcggtcaa cagctaaggc accaccagct
    18601 ggcactgctg tttcatctgc cgaagtgatt actaccgaat tcaatcggcg catttcttct
    18661 ttcaataacc ctactgcatt agccaaactg tttcctctta atgaattgga acatactagt
    18721 tcagcaaaat tacttgtgtg atgcgcctca gtcgatttga ctggacgcat ttcatataaa
    18781 cggacaggga ctcctgcttg tgcgatctgc caagcagctt cacttccggc aagccctgct
    18841 ccaacaacat ttaccatttt caatgaaaga acctcttttc tattattttt ggatgtcttc
    18901 ttcgtaatct ccatttacac agactacttg tttaccgcct ttgactttct tctcgaccag
    18961 atatccgtca cattttggac aatttctgcc cactggttta tcccaagaag tgaattcaca
    19021 ttctgggaaa cgggaacaac catagaatag tctgtttttc ttagattttc gttcaatgac
    19081 ttgtccttca tgacatactg ggcaagtcac accgatttct tttacgattg gtttcgtatt
    19141 ccgacaatca ggaaaattac tgcaagcata aaacttccca tatttcccta attttatcac
    19201 catcggatgt ccacagacat cacaatcgaa tcctgctggt tcatctttga tttgaatttt
    19261 ttcgattttt tcttccgcat tcgtcagttc tttttcaaac ggtttataga aacgatcaac
    19321 cactttgacc cacgcttccg tgccttcttc aattttatcc aaatctcctt ccatttctgc
    19381 tgtgaaatgg atatcgacga tttgagggaa gaattcacag attaatgaat tgacaatttc
    19441 tcctagttca gtcggctcaa atcttttttg tgtcaatttt acatagtagc gtctttggat
    19501 cgtatcaagt gttggtgcat aagtggaagg tcgccctacc ccgttttctt ctagtgcacg
    19561 aatcaacgta gcctcactaa aacgtgctgg tggttgagta aaatgttgtt ttggttcaat
    19621 atcaacagat tggactacat cgccttcttc aagttctgga agaatatttt ctttctcttc
    19681 tttgccgtca tctctacctt ccacatacac ttgcatgaat cctttgaatt tgatttttga
    19741 accgttcgca atgaagatga caccattttg ttctaatgtc actttcattg tatctaaaat
    19801 agctggtgtc atctgactag ccacaaaacg tgaccagatc aatgtataaa gtttcaattg
    19861 atctttatct aaatattgtt tgagttcatc tggtgtacga agcacactcg ttggacgcac
    19921 agcttcatgg gcatcttgtg cgccttgagc atttttgatc tttcggtgat catgtctaga
    19981 aaattctttt ccatacgtat cttcaataaa tgctgcggcc tctgcttttg ctgtatcggc
    20041 aatccgggta gaatcagtac gcatgtatgt aatcaagccg actgttcctt gtttacccaa
    20101 agtgattcct tcatataatt gctgtgctac catcatggtt tttcttgttc gaaagtttaa
    20161 cttacgggca gcttcttgtt gcaggctact tgtagtgaaa ggattcgcag ggtttctttt
    20221 gcgctctttc ttttctactt ttttaacttc gaagtctgtt ccatcaattc tagcagtgac
    20281 ttcttttaca ctttgtgcat ctggtaattt ctttttctta ccgtcgattc cccagaaatt
    20341 tgctttgaat ttcttgcgag cttttttaaa attaccgtcg atgctccaat attcttctgg
    20401 aacaaattct cggatctctt tttcacggtc aataataatt tttaaagcga cagattggac
    20461 acgtcctgca cttaaccctt tcttgacctt acgccagaga ataggactga tcgaataacc
    20521 aacgattctg tctaaggtac gacgagcttg ctgtgcatct actaaatcta catcgatcgt
    20581 tcttggttcc ttaaaagctg ctttgactgc gtcttttgtg atttcattga agaccacccg
    20641 atttttttct ttcagatcca acccaagtag gtacgctaaa tgccaagcaa tcgcttctcc
    20701 ttctctatcc gggtcacttg ccaagtaaac tttttgagct ttttttgctg cggctttcag
    20761 gcttttgatg acatcgcctt ttccgcgtat agaaatataa tggggttcat aattgttttc
    20821 aaaatcgata cccattttac ttttcggtaa atctcttata tggccaacac tggccattac
    20881 tttatagttt cgtccaagat atttctcaat tgtcttggct tttgcaggtg attctacaat
    20941 cactaaatat ttatacgcca ttactgaatg gactcctttc cattgtcgtg ttcctactat
    21001 taaaagagga ttcatacaaa tcgtagctaa tcatatccat tcagaaaacg tttgtcaaga
    21061 aaagcaaatg aaaagtatgg tgttattctt taaattctgc caagatatct tcacccgaaa
    21121 ccgtgcaaac tgcaccgtct tggatcaaat gatgacatcc ggtagaatgt tctgttaaaa
    21181 tatttcctgg aacagaaaaa actgttcttc caagatccaa tgcttgctgt gctgttatca
    21241 gagagccgct ttttttcttg gcttcaaaga cacatgttcc tttagacaaa gctgcgataa
    21301 tccgatttct cattggaaaa caatgctttt tcgggccgga ttgaggagga tattcactca
    21361 aaagaagatg atcatttgca atcacctctt gcaagtcacg attttcagca ggatagactt
    21421 gctctatccc tgttccaatg actgcgattg tccgtccacc atgagagatt gctgcttggt
    21481 gaccgtatgt atctatccct ttcgcgcagc cactgacgat cacatatcca gcttctatca
    21541 ctggttttag taaataataa actgtttttt tggctaaagc agaagtgtgt cttccaccaa
    21601 caacgcttaa catgttacaa gaaagtaaag atagatcacc attataaaac agtacaattg
    21661 gcggataggt caagtgaagc agctgagggg gatatttggg atcaaagcaa gtgataaacg
    21721 actgtttcga ttggattttg ccccagttag cgtgaatttc ctgccaactt ttgcgaaaca
    21781 gctcccggtg tttggttatt ttacctatct taatgatgtc ttcaaatccg atttctttat
    21841 aaggatactg catcatccag ttagcaagtg cccattttcc ttgactactg attccttttg
    21901 tataagcaag tttcaataaa ttttcttcta tttgatacat cataaaaccg cctttcgtct
    21961 ctctttctaa taagatacgt aaaagcggct gttttttatt gtaaatattt ttttacaggt
    22021 gcaaaacttt tacgatggat tggcgtaatt ccttgtcgtt caagtccttc taagtgttcc
    22081 tttgttccat aacctgcatt atgcgagaaa ccatatccag gataaagcac gtcatattct
    22141 ttcatcaatt ggtctcgata tactttagca atgatacttg cagcagcaat cgacacagat
    22201 cgtgcatccc ctttgattat tttttcctgc tgaataggca aatccaaggt catcgcatcg
    22261 atcaacaaat agcttggtac aatggacaat ttttctactg cttggatcat cgctaattta
    22321 cttgcttcat aaatattcac atcatcgatt gtctgctgat caacgatccc gatcccgatt
    22381 gccagggctt tttcttgaac ttgttgataa agaagttctc gctttttctc tgataattgt
    22441 ttggagtcat tcagccctaa tatgatctca tttttcggca agataactgc agctgccacg
    22501 acaggtccag ctaatggtcc tcttcctact tcatcaatgc cggcaatcca ttggtgacct
    22561 tgtgcgtacc cttgcttttc aaagcaaaac atttcttcat atttttcctt aattaatgct
    22621 tcctttttca atcgtcgttc aaaagaagcc agtgcttgct gcacgccttt gcgtggatca
    22681 tttcttaatg attctagtgt aggatcatct attctctgta tgcttttcaa tcgttctttg
    22741 atactttgga tggattcagt catcactttt ttgctccatt tcttcgcaac gatccagtgt
    22801 gtatcgtcca agttttcctt gacgaatatc atgcacgact aattcgctgc cacgatcata
    22861 gtcttcttta tacccacgtt ttgctgtaat atccatcagt aattccggtg ccaatttttc
    22921 ttcttgctcg attgataaac cataacgatc gctgattctt cctgaataat atcgggcaaa
    22981 aaagtctaat ccgtaaatcg ctaaatcatc taaatggaca agctggtctt tgatcgcgcc
    23041 tgtcagcgct agttttttgc cgatttcttc atcttcaaat ttgggccata aaatccctgg
    23101 tgtgtctaac aattccaact cattacctaa acgaagccac tgctgacctt ttgttacgcc
    23161 aggcttattt cctgtctgtg caattttctt gcctactagt cgattcatca acgtagattt
    23221 cccaacattt ggaataccta agaccattgc ccgaatagcg cgaggcttga tcccccgagc
    23281 agcatctctt gcccgttttt ctttcaatgc ttctttagcc gcaggtacta gacctttaat
    23341 tcctttactt tcttgtgccg tgatagctaa tgcaagatgg ccttgtttac gaaaatattc
    23401 ttgccacagc tttgtctgtt gtggatctgc cagatccgct ttattcaata aaacaaggcg
    23461 aggtttttgc tgaatgatct gatctagcat tggattacga gaagataaag gtaatcgtgc
    23521 gtctaccaat tcaaatacga tgtccacata tttcattttt tcagaaactt ctcgtcgggc
    23581 ttttgccata tgtcccggaa accattggat ggtcattgtt ctctccattc ctttcatacc
    23641 ggaatattcc ccggctttac ttgttttttt ctttttcaat ataaattcac ttttttatta
    23701 taaagaaatt ccatctatta gttaagtgaa agtgaaccag tcctcattct atcacatctt
    23761 cacttttttg atgatgcaaa tttttatttt ggtttctata tatgaatcta aatttttgac
    23821 agcgtttcct aaataagaga tgatagacga acaaaacaga aaggagacga aacaaatgaa
    23881 tagtatggtt tttgttaatt ttcctgttgc tgatgtcaat cgttccgttg ctttttatga
    23941 aaagctgggt tttaaaaaaa atgaagaatt ttctactgaa gaagctggtt caatggtatg
    24001 ggatgacact ttttggataa tgcttctctc tcatgatttt tataaaaaat ttataaaaga
    24061 taaagaaata gctgataata aaaaaacaag tggtgctttg atttcgttta gtgttgaaaa
    24121 tgcggatgaa gtaaaaaaat ttgctcaaat tgcaaaagaa aatggtggta ctttccacga
    24181 agtagatatg ggaatgcctg aagaagaaat gttttcatta gaagtccaag atctagacgg
    24241 aaatacatta gaacccgtat ggatgaagat gtaagcagat aactaatctg acgtttttta
    24301 taacaaaaaa acaaaggcgg atgatacgat aagtattctc cgcctctatt ttttttattc
    24361 gtacaatctc ttttttacag tttataaaag cagtcttctc accctttttt taattgttag
    24421 atgccagtgt atgtaaatca ccaatgtgtc atgacacatt ggtgatttta tggtatcctt
    24481 ttattattaa ctgacaaagg agagaatatt ttgaacactt tgattgcaaa agacgttttt
    24541 agattgcccg aaatgaatgc aagattgttg tcgacctctg ctcttttatt agcccttgat
    24601 gtcatcttat acaagatagc gattggtcct gcttattttc aaatcacatt cggattttta
    24661 agtatggcgc ttatgggtta tctatatgga ccgatctggg ctggtttgct tgaaatgttg
    24721 tcgaacactt taaatttcac gatatttggt tcaggaacgt ttcaagctgc ttttcttatc
    24781 acggctttcc ttggtggatt tattaatggc ttatttttat atcataaaaa gataaacctg
    24841 ccttccgtca tcgctgccca attattgatt atgatcccag tcagcctttt tatcaattct
    24901 tggctgatgt ctgttttgtt tggtgcagat ttcaaagtaa tttttctagg tagattcatc
    24961 aggaatatga tccaaatccc tattcaaata atggttgttt attcatttat caaaacttta
    25021 gaggctagaa aagtgtttaa acgagctgtt tgattttacg tactaaggta gtaaactgat
    25081 tttggattaa acaataaagc gtgcagtctc aacagactgc acgctttatt gtttctcact
    25141 ggatccattt tatttcatca agtggataat agacaaatct tgctttacct agaatatcag
    25201 ttttattgat cgtgccaaac gaacgactat cttttgaaac tcttcgatta tctccaagta
    25261 caaaataatt atcttccgga agcttggatt gtcccgttag ctcttgtagt gtaaagtccg
    25321 tcgtatagga tgcatttgca tgatctgatt tcaggttttt agttagataa ggttccttaa
    25381 ctactttccc attgatcttc aattgatcat tttggtagct gacattttct cctggaagac
    25441 cgattactcg tttgatataa atcgtgccat ctgctaattg aaaaacaaca atatcaaatc
    25501 gtctgatctc cgaaaatttt tccatcacaa ccatatcacc ttgcttcaac acgttttcca
    25561 ttgaattgcc ttccactggt accgggatga ataaaaatcc ccgcaacatg aacgcaagga
    25621 atacagaaac aagtaagtat ttgaatacaa gccagaagcg attaatatag cgttgttttt
    25681 ttgtcaatct ctatcaatcc atccctcttt ttttcattct ttctttatta taagaaaaat
    25741 atcaaaaaaa tgcgactaga tagctgaaat aaaaataatt ctttcaatta ggctattgga
    25801 caaaaaactt ttttgatcat aaagtacaaa actatctctt atatgtcatg attattttct
    25861 aaatattttt cccatgcttc gtcaaagata tccatggacg gcaaatagtc gacattcagt
    25921 tccagataat tagaaatttc ttcgtagcta gagctgtgct taggaaattg gatgtcttta
    25981 ccggcttctg tagcgaaaac agataaagca tcatgtgtgc caccgcctcg cagtgtcatt
    26041 aaataatgaa aaaagcttcg attcaccctt cgttcctcca attttcttcg ataaaggcag
    26101 cccggcgtgc atggtttctt ttaaaatttt caggatgctt tttataatac tcttgatggt
    26161 cttcttctgc tagataaaat ggttgggctg gttcgatttt tgtaacgatt ggctgttcga
    26221 aacgtccact ttcagctaac tgtttcttac ttttttcagc aatgatccgc tgttcttctg
    26281 tcaaataaaa gatcaccggg cgataattgt caccgcgatc ctcgaattgt ccgaaagcgt
    26341 cagttggatc agtttgctgc cagtaaagtt ctactaattg ttcatatgaa atcaatgttg
    26401 gatcatagat aatctccact gcttctgtat gtccagtcgt ttggcttttt acttgttcat
    26461 aagtcggatc tggtacatgc cctccagtat atcctgacat cactgtatgg ataccaggaa
    26521 gcgtgtcgaa aggctggatc atacaccaga agcagcctcc tgcaaatatt gctcgttcca
    26581 ttatgattcc ccctctaata ctactcatcc gatgattttt tattttcttt tgtcttgctt
    26641 tcagtactgc tggtgctagt tttgttggta tttgagttgt ttgaagcatc agaggtatct
    26701 tttggcaaat atagactaaa ccgaatgtca tcatttacta agtcgatttt atctgcttta
    26761 atatacatcc cgttttgcat tcggaattga tccaacctaa gcatgatagt cagatcatct
    26821 gtattgactt cgatccaatc tggtaattta tagtttctct tgatcatatt catcacatct
    26881 ttgattggca aactcaatgt tccgatagaa agacttctag cttttagttg gacatttccg
    26941 ttttccatca catacggatc aaaatataaa tagaaatcga taggaaaacc tagtacttcg
    27001 aaagtaccat tgagtagtgc ttcattttcc aaataaaatt tatattcaat atcactatct
    27061 ttttgatact cactaaggaa aaagctgatg atttgattga ctttttcttt atttgaattg
    27121 atcgttaaga caggatctcc ttgtctttcc gtaagagctg gtatttctgg gagttctggt
    27181 tcccgattag caaaaatacg gctgcctaaa aatacggtcg aaccaagtac taccccaaga
    27241 aggataagga aggcgaattt ccagtaattt gttttctttg ttttgtttga agatacgtca
    27301 gatcttgttt tcatgtttat tgatcatcct ccttctctaa ccattggttt tgtgtctcga
    27361 tcagctgatc tctcactgca tttgccatca attgataacc taaattattt ggatggaaat
    27421 gatcttcttc atagagcaca ttatttttga tgccatttag attttctgtc gtgctagttg
    27481 tttgatctgt tccttcttct gtgacaccta cttcctgatt caatccttga taaagcaaat
    27541 cattgattgg gataaagtag cagttcggca ttttttttgt caccgtttct gttcctttgt
    27601 tccaattgtt aacaattgtc tgcatgtcag tgatctcagg aaagttcaaa taaaatggat
    27661 tgtagatgcc taaaatgtaa ataggtgcgg ttttattgag ggatcgaaat tcttccaata
    27721 gttctgtgac attttcctga tagtttttca gtggcttttt aaaggaattg accgttaacc
    27781 cgaataaatt attttggata actttcatca aatcattacc gccaacagtc agtgtgataa
    27841 aatcagctgt tttgatattg tttcgaattt cttcttttgt ttttactcgc tttaagatct
    27901 ggtcacttcg ttcaccattt acaccatagt tttctgtttc aaccgcggtc aaattataac
    27961 ggtcttttag atcatttgcg acaaggggaa cgaatcctcc ttgcttggtt tgatctccta
    28021 ctccttcagt cagcgaatct ccgatagcta tgtagtgaag tttttctttt ttatttggat
    28081 cttctctcac agtagttact ggtttcatta gtgggccagc tttcggtata gaagcagcta
    28141 aacctgcata gatgatgatc gcaattaata atgggaacaa aacgaggatc aaatgtcgtt
    28201 tcgttaattt cattttttca cctcttgtat tcgattggtt ctaatgttat caaaaatttt
    28261 atcaaaaagg tagtctttat gaaaaaagaa aacaattatt ttcctaattt tataaagaaa
    28321 aagagaataa gctgcaagcc tttcaggctg agggcttatc ctcttttcga ctaatctaca
    28381 taatacatga ttgcaaacgc gtctttacca gtatgcgtag cgataaccgg attcgtatgc
    28441 agtacaggga tatgcatgtc cgggaataat tcttgcaaac cctctttgaa ttcttgcgcc
    28501 aattcttttg catccgcatg tgaaataccg atttgtcgca catttggcaa ttctttcagt
    28561 tcatttttca aattattaaa ccatttatcg aacgttttct ttcctcgccc cttagttaca
    28621 gggattaatt cagaatgggc gaaattcatc accacgcgta tgttcaaaac actagacagc
    28681 aaaccagttg ttcggctgat tcttccacct tttaccaagt tatctagtgt ggatattccg
    28741 atgtataatt ttgtattgtc ttgtactttt ttgacttctt caaggatttt ctctactgtt
    28801 ttaccttctt ttgctaattc agctgctcga attacctgaa aagataatcc ttggtcagtg
    28861 gtatcactgt cgataaccgt tactttcgtt tttgttagat tactggcttg tcttgctgct
    28921 tctactgttc cactcaagcc ttttgtcata tggatcgaaa tcacttcact gccgtcttct
    28981 cctagctcat catacatcga gatgaattct ccaattggtg gttggcttgt tttgggcaga
    29041 ttttttgctt tcgccatcat ttccataaat ctttcgccgt ctagttggtc atcatcggga
    29101 tatactgttc cgtcgatcat gatggatagc ggcatgacac gaatgcctaa agcatcgcgt
    29161 acattttttt ccatcgtaca tgaagaatct gttacgattt ttacatttgt cattattttc
    29221 tctctctctt tctttaacaa gatgccttat tcatgttaaa ctacatgtaa gacaatttct
    29281 atttttagta taacagacaa ataatgattt ttcattaatt acacctagta aaggagccgt
    29341 tttcatggaa aaaacgaaat ttaatcgaac gtatgaaata ttaaatgaag tgtttaatgc
    29401 agtcacccat ggaattggga ctggattgag tatcgcggga ctagtggttc ttttagtaaa
    29461 aggtgcccac ttgcattcct ccctccatat tgtctcttat gctatctatg gatcgatgat
    29521 gattctttta tttttaacgt ctactttgtt tcattcattg atttttacaa aagcaaaaaa
    29581 ggtgttccaa gtattcgatc atagttcgat ttttcttttg attgcaggaa gttatactcc
    29641 tttttgtttg ctgagtatcc gaggatggct aggttggact ttatttgtat taatctggtt
    29701 gtttgcgatt cttggcatta tatataaagc gttgacgttg cataaacggg agagagtatc
    29761 aaaagtatct acgatcatct atatttttat ggggtggctc tgtgtcgtgg ctgctgttcc
    29821 tctttatcac tctcttggaa tgactggtgt tattttgatg gtagcaggcg ggctttctta
    29881 cacgataggc gcattctttt atagcttgaa ttctatccgc tatatgcatg ttgtttggca
    29941 tttgtttgtt atgttaggtg caggttttat gtacttctct gttttattct ttacttaata
    30001 aaaaaaataa agctatggat gggacagctc taaataacag ctagtctatc catagctttt
    30061 ttatatcgtc aattcgcctg tcccgctttt tacaggattc tcattacgct gatacgtttc
    30121 aaattgatgc ggataacgat ttttttcatc catttctcct tgactagtat tgatcagtga
    30181 ccaatcagac cagtcaacag gtggaaaata agcatctcca tcgaatacat gatggatgac
    30241 tgtacggtat aatatcgtac aaaatggcag aaattcttga taaacagctg accctccagc
    30301 gatgaaaaag ataccgtctg tttctttttc cagagcaagc acgtcttcca cactatgcat
    30361 gacatgcacg ccttctgctt tataggaaga atctctcgtc aaaacaatcg tctgacgatt
    30421 cggcaacgga cggctaccca tcccttcgaa tgtttttcgt cccatcacta gtgtatttgc
    30481 ttctgtcatt tgtttgaaga atttcagatc atttggcaaa cgccaaggaa gacggtcttc
    30541 ttttccaatc aatccgtttt catcctgtgc ccaaattgca gctaacattt tctcatcctt
    30601 tctgattcta aacagcgata ggagctttga tcgccggatg tgggtcatat ccttctaatt
    30661 ggatatcttc catctcaaaa tcaaatactg actgcttttc ctgattcaaa actaaagtcg
    30721 gaaatgcgcg tatttctcgg ctcaattgtt ctttcatttg ttcgatatga ttgatataaa
    30781 gatgagcatc tcctaatgtg tgaacaaatt cgccaaccgc taaacctgtt tcatgtgcaa
    30841 ttaggtgagt cagcaacgca taacttgcaa tgttgaacgg aacgcctaga aacacatccc
    30901 cactgcgttg atacaattgg cagcttagcc gtccctcttg aacataaaat tgaaacatcg
    30961 tatgacaagg aggcaaagcc atgctaggaa catcttccgg attccatgca gaaacgatca
    31021 atcttctaga atcaggagtc tttttgattg cttcgatcac ttgtttgatt tgatcgataa
    31081 agccaccgtc ttttgtttcc cagtgacgcc attgatagcc gtagatgtgt ccaagatcgc
    31141 cgtatgtttc agcaaaggaa tcatcggtta ggatcttctc gcaaaaaagc ttgctctgct
    31201 ttttatattc ttcattgaat tcaggatctg tcaaacatct atggccaaaa tcagtcatat
    31261 ctggtccatt atagtctgga cttttgatgt agcgttcaaa tgcccattca tcccaaatat
    31321 ggtttttatt ttgtaataga tagcggatat tcgtatctcc ttttaaaaac caaagcaatt
    31381 cgcttttgat caatccaaaa ggtactcgtt tcgttgttaa caaaggaaac cctttttgca
    31441 gatcaaaccg catttggtat ccgaataagc ttaatgtgcc tgtgcctgtt ctgtcttctt
    31501 tacgatgccc ttcttccaac aattttcttc ctaagtcaag atacgcttgt tccatccttt
    31561 ttcctcctaa tcttctaccc attcactcaa gtattcccac cgtgccattt tttcttcaag
    31621 ttgtgcttct gtttcagata cgtcgttttg caattcttgt aatcgagtga aattatctcc
    31681 ttgatgattc atctcttctt ggagcaatga gattttttct tcaagttctg caatctcatc
    31741 ttcaatcgtt tcccattctt tttgttccat gtaagataat ttcttctttt cagcaggttc
    31801 cttgctctgt atttttggtt tcgctttttc agcaggctgc tgggtctctt tttgcttcag
    31861 taaataactg gacatgtttc cgtaataaag ttcttgtttt ccgtttcctt ggaatactaa
    31921 taacttatct gctaccttgt ccaagaaata acggtcatgg gaaacagtga tcacagcacc
    31981 tggaaaactt ctaaaataat cttccaaaat cgtcaatgtt gctatgtcca aatcattggt
    32041 cggttcatcc aataataaaa cattaggttg ctgaatcagc agtttcaaca aaaataaccg
    32101 gcgtttttct ccgcctgaaa gtttgcctat cagtgtccca tgcataaatc ttggaaataa
    32161 aaatcgttca agtaattctg ctactccgat ttgactgcca tctgctgttt ttgcttcttc
    32221 agcagcttct tgtaagtaag caatcatccg tttatctggt gccatttctt cattttcttg
    32281 tgtataatac gcaagatgaa ccgtttcacc gatagacatt gtaccgctat ccaggggaat
    32341 tctgccagct agaatattaa gcaatgtcga ttttcccgca ccatttttac cagtaatacc
    32401 tagtctttcc cgagattgaa tcaataaatc taaatgttct agcagtgttt ggtcatttat
    32461 acggtaactg ccatctttga tttccagtac ttttttccct aaacgttgtg tcgctaggtt
    32521 cagctctaaa tcatcttctt ggtttacttg gtacaagttc tcctttagat cttcgaaacg
    32581 gttgatccgt gcttgctgct tggtgccacg tgcctgtacg ccagccctca tccaagctaa
    32641 ttcctgttta taaagccgct tgcgcttttc ttcttgttct acttctacac gatcacgttc
    32701 tgctttttct aagacgtaag cttcataatt tcctttatac tcgtataatt ttccaaatga
    32761 aagttcgaag attcggtttg ctactctatc tagaaaataa cgatcgtggg taaccatcaa
    32821 tagtgcgcca cggtattgtt tcaaatagtt ttccaaccac tcgatcgctt cataatctaa
    32881 atggtttgtt ggttcgtcta gtaatagtaa atcgggttca tcaatcaaca cttgcgccag
    32941 actaactcgt tttttctgac cacctgataa agtactgatt tttttatcta attcactgat
    33001 tcctaatttt tgcaaaataa tctttgcgtt ggtatctgta gtccaagcat cttctttatt
    33061 catttgttct tctgctttag cataacgttt ttgcacatca gggtcttctc cgttttcccc
    33121 tagttcgatc aatgcttcct catatgctcg aacagtttgg atcaaggggc tgtttccttg
    33181 aaagactgct tggagaacag ttaattcatc ggaaaattca gctgcttgag aaagataacc
    33241 aatacggtaa tcagttggat aaaacactgt ttgccgatca ccgtcgctgc tatcgatacc
    33301 ggcaataata tttaagagac ttgttttacc cgtcccgttc gtcccaatca acccgatacg
    33361 gtctttttcg tggaccaaaa aagaaatctg gtcaaacaaa tctttttcac cataagtttt
    33421 tttgaggtca gttactttta attctttcaa catgttccct ccttatcttg gatattgtat
    33481 cataaaaata gtgaacttca ggaaaatttt tttggtattt gttctttttg tgttctcaaa
    33541 aaaagaacag gaccgattcg atcctgttct gatatgtttt gttttttata aaacttgaaa
    33601 atttttacct ttttatttta ttggactcgt tttttttgac tttgctcgaa acgcaaatcg
    33661 gaaagaaaag ttatcagatg gtttgttcat cgtataagat tctaacaaat tgatattcct
    33721 gcgatagctg ttcgcagaaa acgtcgtgat tttttcagca acttcgtatt catcaatgat
    33781 ttttctttca agataataac ctcttagcat ttttttcgta aacagactat cttgctggat
    33841 catccacgaa gaaatcaaat tccccgagtt catttttatt ccttcaagtt tgcgttgctg
    33901 gataaaaaat tgaaccatcg tttcatcata aatatcagtc aagttatcta aactttcaat
    33961 aatcaactga gtattttttt gatatgtctc tctgatttct tggatatctt catcactaat
    34021 aaatgtctga cgatcagcat atcttctttg ccaaaacatt ttcggatgga gaacgattcg
    34081 cattaaccta cggacaacaa tgaaccaaaa gccgataaaa gacaaaatct ggcttgtgat
    34141 agaatgttcg aatcgagaaa gaaaacggga gtaaaaacga taaccattag aagaaagctt
    34201 gcccgaacga taactttcat ccaatccatc ccgttcgatc gacaaaatca gtgcttgtat
    34261 ttcttgtact tcttgctttt catcatcggt taaatcttcc aagtacagat cacgtatccg
    34321 ttcttgataa ttttctatca ctgcttcagt ggctaaaaat tcttttgtat tacgatcaat
    34381 ttcctttatt tcttttcgca aaacttcaac gacctcttct aaaatcatca aagcattcaa
    34441 atccgtgctt ttcgcttcct ctgtttccgt cagcataggc aagacaatga tccctatgac
    34501 caaagtcact aagatgacac ccgccgtcag aaacaaaagc aaagaccgct ggtaaaacat
    34561 catattattg attgaaaatg gcaaaataaa aatcgtagcc aaactgactg ttccctttac
    34621 accgccaaat gttaagatca agatctcgtt caactgtttt ttgaactttt tactgccatc
    34681 tttgaataca taaaaaagac tgatagaaat gaatctgatc acaaaaagca tgacagagat
    34741 taatacgata atcgctaata aaagaccgtt tggatataaa ccgtctcccc atactggcga
    34801 gaacacttgc gtcaattcga ttcctaaaaa tataaatact aatgcattca gtgtaaaagc
    34861 aatagttgtc catgtactgt gggacaagct cgacaattct gcatcaaaca cagagatttt
    34921 cctaaaacca gaagcttgga gaatacctgc tgccactgca gcaatgattc cagatacatc
    34981 aaatgcctct gccaatacat aggctagaaa aggaagcaaa agttcgatca gcagataccc
    35041 tgtgacatct tgtgctgatg ctttttcgat caaatgaatt attttttgtt tgaaccagac
    35101 aagcaaaaag ccgatcaaag ctcccccaat actagaaact actagactca tccccgcgtt
    35161 tactgctgaa aaagatccgg tgatcagcgc accaagagca aactggaagg cagtaacacc
    35221 agatgcatca ttcaaaagac cttctccttc caaaatatgc atcgcctttt tagggatatt
    35281 cactcgtcca gaaagagaac tgactgctac cgcatctgtc ggacctaacg ctgctccaaa
    35341 agcaaagcag gcagcaagtg ggacacttgg caacaggaat gataacgtcg cacctacccc
    35401 gacaagggtc aaaatgactc ctccaaatgc caagaacaaa attgtcccga aatttttgag
    35461 aatcgaagaa atatctgctt tttctccttc tctaaataac aatggtgcaa taatcataac
    35521 taagaacaat tcaggttcaa aatcgattga ttgtccccac tctgtcagac ctaataccac
    35581 tccaaggaaa atttggatca gtggagctgg aatcattggc aaaatgcggc tagctatgtt
    35641 cgataaggtg atcgttactg caaatacaat aactaactca gcaaattcca tcgtccatcc
    35701 cctttatttt ttattttgtg taagcatttt taaaaattgt tcttttttct ttaaaatttt
    35761 ggtttcgact acttcaacct gtgtttggtt cccctctaat tcacactgta cacgttttga
    35821 ctccaaacga agcagatcat gtttcagacg ttccaactga cgatacatca atatatttct
    35881 tttacgcaac ttacaaagta tttgacggcg gtcatccatc gaaagggcgc catagcgatc
    35941 atgcaacagt tttttttgtt gttcaaaact ctctctcatt ttccagatct cctatacaca
    36001 aacttccatc attatagcaa agttcttttt ggatgaaaaa tatttcattg tttcatcgtt
    36061 tattgctagt tagaaatttc cataaatttt tcaacgcctc attctattcc aaatagtatc
    36121 agatatcaag taaaacttaa gaaagataaa agtttctgac aaaaggatgt ttactttccc
    36181 attcctgcct ttcttgttct tttatcacaa caaaaaaatg gggctgcgac aaaaatcttg
    36241 tcacagtccc ttattctgaa taaacggtgt ggaagagaca gcctatcagt agtaataaga
    36301 cacatctctt tcacagcctc atttttgcgt aaaaatcgat ttattcgaaa aattccccgt
    36361 atacatcttc tacacgttga tctggattga tcacgatata caagttacct gttttttcgc
    36421 tgatttttgt tgattgatat tgattgtcta atccttctgt tcctttatct agatatggga
    36481 agtacacaag atcaggtgtg ccatttcggt aaaggatttc cattcgctcg atatcttcgt
    36541 atttcaatgc gcgattaaac atgcccattt ccagtccgcc taggttgata tcatgtgtcg
    36601 caactgcgtc cccttcatgg aagatttcga ttttaaatcc agcacacgga tggatttcaa
    36661 caaattcact gccattgatt cgtccaaaac ttgttgtgat ttgtttgatc caaagatcgc
    36721 cgatatgacg gcggttgatc gtccaggttt ctccatttct aaaataaaat tttagcgctg
    36781 tcatttcttt actcattaaa aagactcctt tatgatgtaa tttattcttg tactacctca
    36841 gtttagcaca aatttatgta agtggtcaca tcttatgttt tttcttctaa tgacgtatct
    36901 gcccacttta agtagccaac aaagctgagc agatacagtc tagtgttttt taaatcaatt
    36961 tttctttcga taaaaaatcc aaaacctgtt ttttatcatt ttttattctt tgttctacga
    37021 cggctttttc agctaattgc aaagcttcac taacccactt accaggtttt tttccagttt
    37081 cttctagcaa gattttacca tctactgcta attcgcttaa tgacttgata ggtaaacgat
    37141 cataggattc tcctacggca tccatctgag gtgtttcgtc aaaatagatc atcaattctt
    37201 ctacttgcag tgcatgtttt ttgcctaaga agtacaattc gaatggttcc aaagctccag
    37261 tttctcgttg tcgtagtcct tggacaagtg cttgaacgtc tttaatcatt tggttagaac
    37321 acttccacga tttcaaaaag gaacgaatct cattttcttt tagatccagt tggctgatca
    37381 ataatgccca tgcttggctc tcttctttca atgggacgga tggtaattca gcaaaacgta
    37441 aaagtgcttc gccttcttct ttcaaaccgg gacagcaaat gtagcactct gtttcaataa
    37501 atgcatggat tcccgcggcc cgttcatttc ccaagagcat cttgatgaat tccacattta
    37561 tacgttctac agatatttta cctaatagct cgtggttttc tttgatggcg tagaaggttt
    37621 cttcctctaa tttgaaccct agttgactga caaaacgcaa cccgcgcatc attcgtaagg
    37681 catcttcatg gaaccgctca tgaggattgc ctacagctcg caagatctgt tcttctagat
    37741 cttgcagacc atcgaacaaa tcgatgattt ctccatcttc tttcaaagca aacgcattga
    37801 tcgtaaaatc tcttcttttc aaatcttctg ccaacgaacg aacgaattcg acatgatctg
    37861 gtctacggta gtcctgataa gttgattccg tccgaaatgt ggtgatctca tattgttcat
    37921 cattttctaa taccaacaca gttccatgtt cgatcccaat atctatcgtt tttggaaaaa
    37981 gctgtttgat ttcttctgga aatgcgcttg ttgcgatatc cacatcatgg attggctggt
    38041 tcagcaagat atcacgaaca cttccaccta caaaataagc ttcatatcct gcattctcta
    38101 attttttcag aactggaatt gccttttggt attccagagg taattgtttt aatttcattt
    38161 ttccaacctt tcctgcgtgt ttcttgtcct gagataaaga ctcagttgca tggtgactgt
    38221 ttgacaagtc cgtttcagag tcttcaaggc caggaccact tcatcttgtt tactcgtcct
    38281 tacgctcaaa gcgattatgg tctctttgat tgaatttttc catgtttttt tcaaaaactt
    38341 cagttaagtc gatattcaat gaattagcca tgatcatcgt aacgaataaa acatcaccaa
    38401 gttcttctgc taccgagtta actggttcag aagccttttt gcttttttct ccataagtgt
    38461 ggttgacttc tcttgccaat tcacctactt cttcagttaa tcgagccatc tgagctaatg
    38521 gagagaaata ccccaccttg aattgctgga tatattcatc cacttcctgc tgcatactgt
    38581 ataaagaacg ctttttatcc atctttttcc ctccaaaact atcttaccaa aactttaacg
    38641 caaatcctag ataagagcaa ttgagaaaat cgaatttcca tgctacattt aggaaggaat
    38701 ttctaaatgg aaattctgtg aaaatacata attgaaagct ggaattcata tggtcaaacg
    38761 aaaaacagta aaagaagttc tttttatcat tataggaaca agtatttatg catttggtct
    38821 tgtttacttg aacatcgcta atcatttagc agaaggggga gtctcaggga tcaccttgat
    38881 cttaagagct ttatttggta ttgatccagc ttatacgact ttattaatca acatcccatt
    38941 gattttacta ggaggaaaga tcctcggtaa acgttccttg gcctatactg ttctaggtac
    39001 actttctttg tcattctttt tatggatctg gcaaagggtt ccactagaaa tcaatttaca
    39061 gcatgatcta ctgatcgttt ctctacttgc gggtttagtt gcaggtgtag gaagcgggat
    39121 cgtctaccgc atgggtggaa caacaggcgg cagtgatatt atcgctcgga ttttagaaca
    39181 aaattacggc atcactatgg ggcgttccct attggcattt gatatcatcg tcttacttgc
    39241 ttcattaacc tatatcgact tgaaacgtat gatgtatacg ttgattgttt cgtatgtttt
    39301 cagtcgtgtg attgattcga tcttagatgg cggatattct gcaaaaggtc tacttgtcgt
    39361 ctccaacaaa agcgaagaga ttgcaccact actgatgacc ggtctgcaaa gaggtgtgac
    39421 tttcctttct ggagaaggcg cattctctgg taattcaaaa aaaatcatct atatggtcgt
    39481 tagctctagt gaattaactg aagctaagag gatcgtccac gagattgacg aaaaagcttt
    39541 cctttcaatc atcaatgtgc atgaagtgga agggcaaggc tttacttatt tgaagccaca
    39601 gacaagatta ctgaaaaaac tataagaaaa aagacaaaga taggctatga ggaaagattc
    39661 cacatccagc tgacctttgt cttttttagt actatactat ttttaactaa ttgttatgtt
    39721 cacttacccg gttacttttc ttttgtgtct gcaaaaggat ctttcggtta acttcatcag
    39781 ataatttcaa aaaagcatcc ctatctccat cttctagtgc ttgatcgatt tgagcataaa
    39841 gcatttttag ttttgcctct tcttcttttt cttgaaaata tcgttcaatt aattcagtat
    39901 cttcttcact gactgaagaa tcccaagaag aaaatggatt gtcttctaag atagatagat
    39961 attctcttgt ctgccaagca ttttcgaata tacattccac atataaaggc tttttccaat
    40021 tcaaacggat ttcatgaaaa atctggtctg tgtccgtaaa ttcttttccc tgcaaaaaca
    40081 atttcatggg ttccccttca acagatagat cactgatctg cagtcctcga tccgcaaaat
    40141 tcgccccttc aacaaagtgg acattgctta aaatcgcttc atgattggca agataattca
    40201 agatccaaaa aacttctctt cggctaaaag atacatgatt gaccatccac gttaaaaaat
    40261 tcttcttttc ccgtacatca attagcattt ttctcacctc tctgttaggt catctaataa
    40321 tgacagtgcc tccatatctc ctggttcaag tgttaaataa taagtcaata attcttgcgc
    40381 tcttttcagc tgcccttctt ctcttaagaa aaaggcatac tctttcaaga aatctggttc
    40441 atgtgatagt tcatgataag cctgttcata gtgtacagct gcaacggtaa agtcttctaa
    40501 ttcattataa gcatgggcta ggttccattc tgcataagga ttagcagttt cttccatctg
    40561 attgatcact tgtatcacat cttcatatct ttcatcatcc aagtaaagat tacttaaagt
    40621 aagtaatgtt tcatcttgtt tgtctcctac ttctaaagct ttcagtaaaa gttcttctgc
    40681 tcgctgtcta tcatgcagac ggaaagcatt ttccgaggcc aggtgataaa gttcgacttg
    40741 gtaaggattt tctttgattc cttcttctaa cactgtttgt gcttcttcaa tcatttcttc
    40801 ttcttgaaga gcttgtccta gatatagata taacgattga taatgcggat taacttctcg
    40861 aagttcttcc agatagttga ttgcctgctg attttctttc aattgaagat tcgtaaaagc
    40921 tagctggaac agtcgatcat ctgtcctttc ttctttcagt gcttcttcta aaggtacgat
    40981 agctgcttcg aattctcctt gcatacttaa ggattgtcct aaacgttcct gcatcgagat
    41041 tcctgaaatt tcatttatcc cgcttgccaa caatgtttca taaaccactg ctgcctcttt
    41101 gaaacgatca actgaaaaat acaattcagc tagcgcaaac tggatcaatg gttcatcagg
    41161 aagcaaccca gctgcttctt tcaattttgc ttcactcact tcagggattc cgataacttg
    41221 gtacaaatca gctatcgcca ataagctttg cggatagtaa tcactttgct tatccacttt
    41281 ttccaggtat tcaaaagcta agtcgatctc attatcttcg attgcaattt ctgctaacgg
    41341 gatgttcagt ccgtcatttt ctgggtattg gttgatcagt tgttcaaaaa tctgttttgc
    41401 ttcgatcaaa aagccaatag ccagcaattc ttcgcctagt tcagctaata tatctgctgg
    41461 gtcttctttt aatgcttttt ctaaaaagat ttgtgcttgt gacaagtctt catctgataa
    41521 agcttgcaac attttttcgc tatttgtatt catttcaatt ccctcttatc tcactgacga
    41581 tttgttgaaa taccgtcatt gttctcaata attctttttc gtttggatgt tggtatccgt
    41641 ctattatacc tattttttct aaaacaagta tttttttgct tttttctgcc aaaaaaagaa
    41701 ctttttccaa atactccatc tttgaaatct gttccagcca gtggattgga tagccaagca
    41761 agtccagcca cacaaaaaag ttttttagtt ggaaatcaaa aggatatgct tggagattcc
    41821 acacgaaatg aaacatcatt cctaaaaatt ttttcatact agcagaaagt agatggccat
    41881 tttcggtcag ataaaaagct tgttcaaaca gtttaccata atttgacagg ttttctgcct
    41941 ctaattgata aaaatagatc atttcttcga tcatcccggc aaacggccga gtcgttaatt
    42001 gctttttatt tggatagttt ttatacagat tttgcaaaaa acgatgatca caaatcattc
    42061 cgcaacagat aaaagtcaaa aagtcaatct gctttccgtc cacctgccgc tcgctgattg
    42121 tttgatcata aacgatgcgt tctggcagat tgatggtttg cagcactaca cgatttggta
    42181 gctgcaaaat cgtccgctgc ggtgttaatg ctcggcttag agaacggatc gatacaggga
    42241 tcatccatag tgatgaatca agggttgtat gtttttgaaa aaaacctgcc agatccatga
    42301 tcccttcatt tccaaatccg atgataaaca tggattgatt ttcgggatag cgtttgacga
    42361 aatcaagcag gttctttaat tctgttaaat gattgcattg agtgttggca caaatatacc
    42421 agtcattgtt tgcttgattt gcaaataacg ggttgatctt atctgcaaac aaatcataat
    42481 agcgctgatt cgttaaaaat aagattggct gatcaatgga aagttctctt agctgactga
    42541 ctagcgtttc tccgtaaaac actttcgtca acgcatcttc tacttgataa tcaagttcca
    42601 tacgcatccc tcctcttctt atttttattt taccattagt aagcaaattc tagaaaagat
    42661 aagagcaaag ctcacctcat aacttgcaaa taaataaaaa ttaaataaaa tacatgtgtt
    42721 ttctatgtat gacatacgga ttcggaatct ctgtctctta tttattcctt ttctgctagg
    42781 aaataaaaag aaaagcactt gtagccctag agccacaagc gctttttcaa ctgtcttatt
    42841 taacagcgtc ttttaatgct ttacctggtt tgaatgcagg tactttgcta gctggaattt
    42901 cgatttcttc accagtttgt gggttacgac ctttgcgagc tgcgcgttcg cgaacttcaa
    42961 agttaccaaa accgattaat tgaacttttt cgccgttagc taaagcatct tgaatagttg
    43021 aaaatacagc atctactgct gcagttgcat cttttttagt taaatcagta gctgaagcaa
    43081 ctttttcgat taattctgct ttgtttgcca tggatagatt cacctcctcc acaagagata
    43141 tgatagaaat atcatttagt taaaactttc tgagtggtcc agaagtttaa aaagaaatat
    43201 tgattaactt caatattctg ttatcacgat atcatatgaa ccgcttaata gcaaggtttt
    43261 taccaatttt cacatgcttt ttttagtcat agaaacgtaa caaacgaaac tgtctttttc
    43321 ttttgaaaaa aaaacgtcga tatggtaaaa tgcctatttt ctcctacgag ggataattcg
    43381 gatggacgtc ccttcaaaag taaatgcttt tctgatttga ttttctaaga aacgttcata
    43441 agaaaaatgc atcaattcct cttcattgac aaaaacgaca aatgtaggtg gtttgacagc
    43501 gacttgtgta gcataaaaaa tcttcaggcg ttttccttta tctgttggtg ttggattgat
    43561 tgctacagca tccataatga tatcattcaa cacagccgaa gagatacgaa gattctggtt
    43621 catacttact tgttcgatca tttcaggcag acgttccaac cgttgtttag tcactgcaga
    43681 aacaaaaacg attggagcgt aatcaagata ccggaattca tcacgaatct cttgttcgaa
    43741 atcacgcatt gtattggttt ctttctttac aagatcccat ttattcacga cgataataat
    43801 tccacgacca gcttcatggg cgtaacccgc tactcgcttg tcttgttccc gaatcccttc
    43861 ttcagcattc agtaccatca aaacgatatc agaacggtca atggcacgca ttgcacgcat
    43921 cacgctgtat ttttcagtat tttcgtatac ttttccgcgt ttacgcatac cagctgtatc
    43981 tatcattaag aatttctgac cactttcaga aacgaagtgg gtgtcgattg cgtctcgggt
    44041 cgttccttca atatccgaaa caattacacg ttcttctcct aaaatcgcat tgatcaaaga
    44101 ggatttacca acatttgggc gaccaatcaa actaaactta atcgtgtcgt cgtcctcttc
    44161 ttcagtctct tcagagaaat acttcactgc ttcatctaaa atatcaccaa tccctagtcc
    44221 atggcttcct gaaacaggat aaggatcgcc tagccctaag gaataaaatt catagatatc
    44281 gtttctcatt tctggattat ctactttatt gactgctaaa atcactggtt tattacttct
    44341 gtataaaatt ttcgcaacca tctcatctgc gtctgtcacg ccttcgcgtc cgctgactac
    44401 acaaatgatt acatctgctt cttcaatcgc gatttctgct tgatgcttga tctgatccat
    44461 aaaaggttca tcgccaagat caattccgcc tgtgtcgatc acgctgaatt ctcgacctaa
    44521 ccattcacct tttgcataaa tacgatcacg agttactcca ggagtatctt cgacaatcga
    44581 gatacgctca ccagcgatgc ggttaaaaat cgtagactta ccgacgttcg ggcggccaac
    44641 gattgcaatt gttggatttg ccatattatt tcctcctcac aagtttccaa tctcacttag
    44701 tttaacgaat gcattgccaa ctttcaagca tagattgtca attaaacgaa gtatttttat
    44761 tccttattga aatactaatc gcttttcaaa agaaaaactg agacaaaagc agctgctttc
    44821 atctcagtca cagatacaaa atcaattatt tttcagaatc atcggttgct ttttcttcta
    44881 cttcttcttt caacgcatca cctaaaatgt ctcccatagt aaatccagta ttttcttctg
    44941 gtaattcata agactcaaca ttttttggtt cttcttctga agctggtttt tcttctaaag
    45001 ctttgatact caatgcaata cgatgttctt ctggatggat ctctaatact ttcactttca
    45061 cttcgtcacc ttcatgaagc acttcatgtg gtgtcgcaat atgtttatgt gaaatttgag
    45121 agatatggac tagcccttct actccaggga acacttcaac aaaggcaccg aagcttgtca
    45181 aacgtttaac tgttccgtct aatactgtgc caactggagc ttttgtatcg atttctgacc
    45241 aaggtccagg ctgtgtgtct ttgattgaca aggaaacacg ttcttgttca ggattgatag
    45301 acaacacttt gacatttaca tcatcattga cagccaatac atcacttggt tttgctacat
    45361 gactatgtga aatctctgag acatggacta gaccgtcaat tccgcctagg tcgacaaatg
    45421 cgccaaaatc agtaagacgt gcaacacgtc cactgagaac atctccctca tggatagttg
    45481 aaagaatttc ttttttcttt tcttctcttt cgttttccac taccgcttta tgcgataaga
    45541 tcaaacgatt ttctgatggt tcgatttcga tgattttaaa gctcaatgtt ttgcctttat
    45601 agtctgaaaa gtctgcaaca aaatgatctt ccaccattga tgcagggaca aaaccacgta
    45661 caccgacgtc aacgactaaa ccgcctttga caacatttgt aacaggtgct tcgatgacct
    45721 tgccctcttg gaaatctctt tcgatatctt cccaaacttt tttagcatct aaacggcgtt
    45781 ttgaaagtag atagctgccg ttttctttat ctttgccgat cgtactgata acgactaaat
    45841 ctaatacatc accgactttt actacttcgc tgatatcttc taccggcaaa gttgataatt
    45901 cttttgccgg aacgactcct tcaactccag ccccttcgat tccgacaatc acttgtttgt
    45961 cttcaatgac taaaacttcg cccttaacaa catcgccaac ttttacttct tgtacgcttt
    46021 tcattgcgtc ttccattgac tggttgttct cttgattttg atcaaattct gtcataacac
    46081 ttgtcctcct aaccaacatt ctgccgtaag tacggtactg tttttagttt aattgattat
    46141 tcaaaaaaaa taaagcgatt tcgttcgttt tccttgaaaa aacaattgtt tttcattttt
    46201 tttcttaatt taaaaaagaa gataaccttt tttcaaaaca acagctttta ttgctgcaac
    46261 gacttctgga atcgatttgc cagtcgtatc gatacgaaca gcatcctctg cttgcttcag
    46321 cggagagacg tcccttgttg aatcataatg gtctctttcc tgtatctctt tcgtcagtgt
    46381 ttcaagatca gtcggaattc ctttttcttg gttctctttg aaacgtcttt ctgcacgctc
    46441 acttacgctt gctactaaaa agattttcac ttctgcattc ggtaatacag ctgtcccgat
    46501 gtctcttccg tccatgacaa cgccaccgcg ttcccctatt tttcgttgga cagcaactaa
    46561 ttcttctctg acttttccat gtgcagagac ttcagaaaca gcttttgtga catctggttg
    46621 acggatttct aaagtcacat cttttgatgc tatgaataca tgctgtccat cttcttgttg
    46681 cgaaaaagag ataggatact ttttgatcag cgaaactagc ccttcttcat ctgaaaaaga
    46741 tacattgttc gtaatagcta aataagttac tgcgcgatac atggcaccgg tatctgtata
    46801 aatataattc aattcttttg ctaatatctt ggcaacggta cttttcccag atgaagcagg
    46861 cccgtcgatt gcaatactga tttgtgtcat gatataactc ctttttctca gaaaaaaagc
    46921 cgcaaagcgc ggctattatt atttaattct taattcttga ccagggtaaa gcataaagtt
    46981 gtttggatct aagccattca attcaaacaa ttgatcagtg gtgatccctg cacgctcagc
    47041 cacttgtttt ggaccttcgc ctgcttgaac agtcgttgtt gaaccggctg cagctgatga
    47101 agaaggtgtt gtttctgctg cattgctgct tgaatcccct gcttgataag ttgcctcact
    47161 tgaggaagtc ggtgttgtct ctgctgcaat actgctttct gacgttacac ctgtatcttg
    47221 agacacagta gattcttccg cgattgtact agattctact gttgaagtct cagttgactc
    47281 ctcttttgtt gtacttgtag aactttctac tactgatgtc gaagtttcag aagaagttgc
    47341 tgctgttgca ttgttgcttg atccatttct gatccagaaa taagcacctg ctggaatagc
    47401 gatacataag accagtaaaa tcaaaaatag cgaaagaaat aatgtatttc ctttcttttg
    47461 ttgtctctga gaacttcttg atgaaacttc atcatctgta tcgtagattg gttgttccca
    47521 tggttcttgt gtttcgttat tttctgtaga ttgatgtcta tcttttctgc tcactgtttt
    47581 acctcctaaa ctctatcgtg tgtattatac cataggaaaa agtgtcttgt cctaaaaaat
    47641 caatgttcca tgtttttttt aaataaattt agtaaaatcg ttccccaatg aagttgttca
    47701 gtcttagaaa aaagcttcct ctttggcaga agttctgctt ttgctccatc aatatcacaa
    47761 caattctgcg gcttttcgga gagtttttcg ccaaaataag ctaagatgaa ttttctgcgg
    47821 cagttttctt cattaatata gcgaagcatc tgctgcaggc ggaattcttt ttctttttcc
    47881 tgacgtttga gccgttccac ccaattttct ggtttttcag actgctggat cagctccatc
    47941 catttttttt gcagctcatc aaagggagct tgctctgtgg catattccaa ataaagctca
    48001 aaactttgtc gctgttctct agaaagttga ttaaagaaat aatggatacg ttcatcccca
    48061 ctttgataaa aaagaattgc tgcactttct tcctgatctc tgcctgctcg accgatttct
    48121 tgtacatagt tttctagact gtctggcaaa tcataatgga ccacataacg gatatcagat
    48181 ttatcgatcc ccataccaaa tgcattcgta gcaatgagaa actgcagctg attttttaca
    48241 aactgctgtt gaagttgtct tctttgagct gcatcaagac caccgtgata gtatccaact
    48301 gtaaaacgtt ccctgaataa atgatacaat cgttcgactt ctttttttgt tgcacaataa
    48361 atgattgccg ctccttgtgc tctttccatg aagtgttcaa gttcttgttc tttttgctgc
    48421 gttttccgaa caaaaagcga gatattttgc cgattgactg attgtctgat ctcttttggt
    48481 ggtcgatcaa atagtacatg acgtatatct cttgctacta aatctgttgc tgtcgccgtt
    48541 agtgccagtg tgaccgggtt tcctaaaagc tttcggattt ttcctaactg ttgatattct
    48601 ggacggaaat caactcccca ttgagacacg caatgagcct catctactac atataacgca
    48661 atattttgtt ttttcagatg ctctaaaaga gaaggattag tcaacatttc gggactcaaa
    48721 aacaaaaatt tatattgcga tagatgacgg aggacgtatc ttctttcaga ttgcgaaagt
    48781 aaactattga aagcagctac tcgtttctcc cctcgttttt gtaattgcgt cacttgatct
    48841 tccattagag aaagcagcgg tgacacgatg atgaccagac cttccattaa ataccccgtc
    48901 aattgatagc aaaggctttt tcccgttcct gtaggcaaaa tagcgagagt atcttctcca
    48961 tcaagcaacg cctgaataat ttcttcttgg ccgggacgaa atgaatcaaa tccaaaatat
    49021 ttttttaatt catttattaa cattctgtat cgcttccttt ctcaatagat agatttgata
    49081 caaacgaaat tctccataat ctaattgtcc atctacattc cattcgctaa agcgccactc
    49141 tcgcacggaa tccttatttg gttccaaacg ttcgattgtt tctgcagaga gaatccactc
    49201 gtatggaaaa tcatcaaaaa acaaggccca ctcaataaga tgatctgtta ctgttcctct
    49261 ttttaaatga cggattgcca tgatctggtc aattgtctga ccattcataa acatctgctt
    49321 ggtgatcatc atgctttgat tgaaattttg ctgtaataat gaatcgatca aagcgtgcca
    49381 aagcgaatct ggccgttttt cgatttgtgc taacaaaagg tggatacatc tgctttgttg
    49441 cagataaacc gctgactcat cattgttttt tgccagctga taaggaagca gccctgttcg
    49501 ctcatttcca gataattggt tagctaaaaa atctgctgct tcttctggta tctccgaaaa
    49561 cagctgcacc aaactctcat acgcagtatc aatcaaaatt tcacgtggca attggctttc
    49621 actaagccat ttttttagtt ggaaagtata aaaaggactt gtctctgctg gaagatagtc
    49681 ttgaataccc gttgccagat tagaaattac ttgaacagca aatttaatga gccgccaact
    49741 agtttcccct gttctgccat agcggtcaaa acgcaaacca gtatgttcta tttgatgttc
    49801 ggacaacata tcagcccctg caggcgttag ctttgcttca ttttcattta tttcgatcca
    49861 accttgctgc gcaatttttt gcaaaatttg ataaaactta tcctgcttca attctggaaa
    49921 actgttatgg ataaacaaaa gttcgtgggt aaatccataa ataagtactg aagtcgttcg
    49981 ttttcccaca aggagttggt aaagagaact aatccgcagc ttgtgtcctg atgaaaatag
    50041 cgataaaata aaaacaatca tattattctc cttaagttag gatggttaga aatgtcacta
    50101 ctatgtaaac ttgtacctga acgctgtatt gcatgcggtc tttgtcaaat cgaagcgcca
    50161 gatattttcg attatgatga agaaggaatc gttttatttg cccaagaacc agaggctcat
    50221 caacagttcg tgatgccgga agaagaaaca tatgtaaaaa aagcgtatca aaaatgtcca
    50281 gttcgagcga ttttattaga aaataaaata taaatataaa cgaaacttta aaaacgtaca
    50341 ctaagttctc taaacttgaa aataagccgg gatctgtttc tcttgttccg tgaaatcccg
    50401 acttattttg aaagattcat ttgctatcta tagttaattg actagttttt tcacggaccc
    50461 tataggaccc atttatatta tttcaacttt ttcagccagt tttccaatgt attgacgatc
    50521 acagtttgct ggtctgcgtt agaaatttct gcctctccat ctcctttttg ctcaccatag
    50581 ctgccaaaac ctccatgatt tccgccattg attgatacat actctgttct ttccggtaaa
    50641 tactgcttag cttcttgata agcttcctga ttcaatactt tatcttttgt cgccgtgatc
    50701 gataaaacag gaacagctga ttctgtcaat gttccttttt tgtcgggata acttgccatg
    50761 aagaataccc cttttaaatg tttgtctgaa tgattcttat tgacataacg acttgccatt
    50821 acgccaccta atgaatggcc accgatcaca taatcggaat ttggaaaatc ttctttgacc
    50881 ttatccgctt tgtttccgcc catcactgct agatcaagtg gcattttgac aatagcgact
    50941 gaaaagccgt tttttgctaa atcttgcgcc caaatactat aactttctgg ctctacgaga
    51001 gcaccaggat aaaaaataag taatggagac tttccatgat tctttttctc tccttcaaaa
    51061 aataagtaat cttctttgtt ttttccttct tttaccaaca cttgcgcttc tgacgatggt
    51121 tcgtacgtat tttgctgtat atagtaataa ccggctccac cgagtaatcc taaaatgatg
    51181 actaagccaa ttagtattcg tctaaatatt ttcactttct cccacctttt ctatctgagt
    51241 gacccctttt tcttaatcaa gtatgattat accttaaaaa aataagagag aaatgcaaac
    51301 tttccagcat caaataaaaa aagacggaat atccatttga atatccgccc tttttgtatg
    51361 tttattttta tttagcacat aaacgataca cagcttctgc ataaatttcc attgctttat
    51421 acatactact taattcccat cgttcattcg cctggtgcat aaagtcagga gtatcaggga
    51481 acatcgcacc gaatgccaca cactggttca tcgtacgagc aaaagtagcg ccgcctgata
    51541 caaacggttc agtcatgtct ccagtaatat cgcgatatgt ccccaataga tttttcacta
    51601 actcactgtc tagtggcacg tataatgaat caaggaagtc aaattcttca taagtcaacc
    51661 catatttttc tgctgtttta gttaatttag ctactaaatc atctttcttg aatgtaacag
    51721 ggattctcat atctacaccg atttttgttt gttctggtgt gatttccaaa cttgcaaagt
    51781 tcatcgttag ctcgccggat tgttcatctt ctgttttgcc cacgacagct tcaccagttg
    51841 cattttcttg aactaatttt cctaagaaat tgattgggcc aaaatcaaat acttctgaaa
    51901 gagcaattgc cagacgagaa atagcattca ctccttgtgc tgcatctttc gcgtggatac
    51961 ttttaccaag aacgacgatg ccttcacctt gttcttcgaa atcgaattcg tgttttttca
    52021 atgcttcttt tacttcagaa agcttttctc cagagtaagg agctgcatca ggaacaacat
    52081 tcaacgctcc tccagctttt acagaaaact cgttcgttcc tggtcctgtc aagtaagctt
    52141 gcaataagcc tttttctgca taaattaaag gaaattcagc atctggcgca aatccttgcg
    52201 taattccttc ttctttttcg ttatattttt ctaaacaacg ccataaattt tcttcatctg
    52261 taccaaagat aaaacgaata cgtgtcttga attccacgcc agcatcaatc aaagctttga
    52321 cggcatacat tgccgcaata gaaggacctt tgtcatcttg ggatccgcga ccaactaacc
    52381 agccgtcttt tatagttgga tcgaatggtt ttgtttccca attattttcg tcccctgctg
    52441 gaacaacgtc catatgacac aagataccga ataattcatc tccagagcca atctctgaat
    52501 aaccgtaata gccttctgga tctttaaatg ttctaaatcc tagcttttca ctgatttcca
    52561 atactttatc caaagcttca atcacttttt taccgaaggg atgtccttgt cctgaatctg
    52621 cttcatctag tacggaagga attcggatca attcgctcaa tgattctaat gcttgttcat
    52681 gatgttgttc tgtcacaaat tttttcatga tattatcctc ctaatatgtt aaaaagggtc
    52741 atgtcaaatt cctccgacac aacctcttct tctcaaataa tgacgtttta agcctgctcc
    52801 atcagcaagc agaatgttct taacaaatga tgaaagaaaa aacactcact gaatggagct
    52861 attgacttat ccacgtgctt atcgatagcc gtttatcggt ttcttcattc ttatgataga
    52921 ccttgtacct gtatttgtct aggtttagaa cattgctgct acacctagga tcacacagat
    52981 ggctacaaat aatatcgcaa ttaatttacc ggtaaatttc caccacactg aaacatcgaa
    53041 acgagcaatt gctacagcac ccattacgat agcagatgtt ggtgtaatta agtttactaa
    53101 accagatgca gattgataag cagtgattac taaatcctta ccgacgccgg caaattcacc
    53161 cataggtccc atgattccca ttgttgcagc agctaagccg gaagttgaag gaatcaagaa
    53221 tgacataggg atatagaaaa taaatgtaat aatgatgaat acacttgaag ataatgaact
    53281 taatccttgt tcgccccaat gtaagatggt gtctgtgatt aatccattgt tcataaccac
    53341 ttggatacca cgagcaacag ctactacgat tgctacaccg atcaaatcag aagcaccagc
    53401 taaaaattca gagacaaatt cagactcttt catgccataa gtgattgcta ctacgatgga
    53461 cattactaag aataacatag taatttctgg gaagtaccag tcacctaatg gaagcatgct
    53521 tttacctaga accgtaccta gtaccggaag gtttgttaac cagtttgtca atgattcaaa
    53581 aatcgtgaaa ttcgcattca aggttgtcca aggaatcaaa ctgatgatca tgataccaaa
    53641 agtaataaag aacaatacat taacatgttt ttgttttttc gtgattactt cttgacgacc
    53701 gattgcttca atatcgaaat gcttcatatc ttctttacgt tggttgtata ctaatgattt
    53761 tgttggatct ttttcgatct ttgatgcata acgatacaca tatacaatag aaatagctaa
    53821 caaaataacg aacatcaaga atcgaagacc aataccttca cccatcgaaa tcccaacagc
    53881 ttgtgaagct acgcctgttg caaaaggatt taccgttgaa gctagacagc ctacttgaga
    53941 ccctactaat acgattgcta cagctactac tgtatcaaag cctacagcca tcatgactgg
    54001 gatcagtaaa gcatagaatg gaatcgtttc ttctgccatt ccgtaagtag agccgcctaa
    54061 tgcaaataac agcatcaata ctggaataag cattttttct tttcctttga atttcttcac
    54121 aactgaagca atcccggcat ctagtgcccc tgttttgttg ataataccta aaaatccacc
    54181 aacaaccaaa atgaagaaag agattgggat tgcagcaggt gtttctttag ttagctcccc
    54241 cgctggtaca cctagcatcc cattgattgg cgccatgaaa atatcccaca gcccttgagg
    54301 attttgttgt actcgttcat atgatccagc gacgatgttg cctgcatcgt ctacactata
    54361 gtgcccagct ggtataaacc aagtaagtac agcgattact gcaataataa taaataagac
    54421 cgtatacgct gaaggcattt gaaatttttt cttttttgtt tgttccatct tcttcttcct
    54481 ttcttttccg ttagagacaa caattttggc tctaatgtta ttttatcaaa aagagtatca
    54541 gaacaaaaat aataacacgc attttgtaaa acttttgttc aaaaagttcg tttttcccta
    54601 ttccctcctc ttttttcagg tttttaaagc tttcttcttt ttcattgtag cgtttccttt
    54661 tttttataaa caaacatttt cgtcttttaa aaggagaaga atttcacatt tgcaaagaat
    54721 tgattgattt ttatgcataa atcaaaaaaa tactcaaaac aaacaaataa aacgtttaca
    54781 ttattgcatg tcttgtattt ttttccaaaa aaaaagacca agaaatttct tgatcttttt
    54841 gatatttatt tgactgctgt atgacgttgt tcgaactgat gttgttttcg acttaaccat
    54901 ggaagaagtt gcgcatgcag cactaaaaag acagcactca cgatgaatcc tttgatcaag
    54961 ttgaaaggaa cgatcccaat cagtacatag tttgctaaag acatgcccag catctgtgtt
    55021 gcgttcagcc ctaaaaacat taagtaaaga ggcgtaataa cgaaataatt tgcgatactc
    55081 ataaaaatag ttagagcgat ggttcctgta atgacaccta aaaatttgtt tcttccttta
    55141 tgctgtttct ttacactaaa gaaataataa atcgggaatg taaagatcgt tgttgataag
    55201 aaactagcag tgtctcctac caaattatcc ggagaaaaac ctgtagtcag cagatgtaat
    55261 actgaacgca agaacgctgt tgcaactccg gccgctggac cgaataagaa catgctgatc
    55321 aataccgaga tatcactaaa atcgatcttc aaaaaactaa aagccggcat gatcggaaaa
    55381 gcaaaatact gtaaaactaa tgcgatcgca gcaaacatcg ctactgcaac cattttctgt
    55441 acacgggtgt tcttcatttg aaatcctcct gttaggactc ctcttcagcg aactttttga
    55501 cgtttctctc caaatgaaaa aactctattt tccagggaaa atagagttag agttatttga
    55561 tcaagcgtcg tcaaataagc tctatcttct ttatccagac tatactgtcg gtatcggaat
    55621 ttcaccgatt cagctatttt tttgcaaaat aggtcgtgga ctataaccac cggtcgggaa
    55681 tttcaccctg cccctgaaga cgaaccttat ataatttttg tttacatatt cattatacat
    55741 atctattcaa aaaacgcaac atctaacact tataaaaagt aagtgttcat tttgagtggt
    55801 tcagcaaact gctgacttct tttttgttca gttcacggta atccccagga cgtaggcctt
    55861 gtaaagtcag atctccgtat ttttcacgtt ttagtttttg cacaggaaga ccaactgctt
    55921 gaagcatatt tttcacttga tgattacgtc cttcgtggat cgtcaattcc acgatactgt
    55981 ggtttgtctt aggatccact gataaaattt ggaatttagc tggagatgtt tttcgtcctt
    56041 cgatctttat tccttttgtc aaaggtgcaa gcatcgattt tgtagcgatc ccttttacct
    56101 ttgcaacgta aactttatcc acttcatgtt ttggatgtgt caggcgctga gcaaaatctc
    56161 catcatttgt cagtagcaag atccccgaag tatcgtaatc cagtcgacct acaggataga
    56221 tacgttcttt taccatcggc aaaagatccg taacaacttt tcttcctttg tcatctgcaa
    56281 cagcagaaat aactccttta ggtttgtaca ataaatagta accgtattct tcttgataaa
    56341 ttgggacttc atccacttcc acagtgtcat gtttcccaac ttttatccct aattccctta
    56401 caacttgtcc gtttactttt acacgtcctg caaggatgaa ttcttctgct tttcgacgag
    56461 aagtgatgcc agcgtgggca attactttct gcaatctctc cattacaatt attctccttt
    56521 attcattcca tcaaagaata gatctggtga cacgtcttct tcaagtgaaa tttccatttc
    56581 ttgtgtatca ggcagttctt ctaatgattt caaaccaaaa taatctaaga agtagccagt
    56641 tgttccatat aatatcggcc gacctggtcc ttctactcta cctttttctt caatcagttt
    56701 atgggcagct agacgctgta ccgctcctga aacctgaact cctcgaatct gctcgatttc
    56761 agctcttgtg attggctgtt tataagcgat gattgctaag gtttcgacgg cggcttgaga
    56821 taatgtgttt gatgtccctt gcgcatatcg cttaagtaag ggagccagct cttttttagt
    56881 cgttaataca taatggcttt ccgtttcaaa aatatgcaaa gctgagtgcg agttttgagt
    56941 gtaagattct tttaattctt tcactaaact tgtgacttct gcttcgctga gatttaacag
    57001 tccgcttaat tcttcattac tgatcccttc ctcgccaaca ataaaaagaa gggcttcaag
    57061 ttcacttaat ttcgtcatgt tcggtatctc ctactgctgg ataaagcata attgattcat
    57121 agttttcttt ttgttgcgca atgatctgcc cttttttcat caattctagc aaagccataa
    57181 aagtagtgac aacttcactt ttagaaggtg actcaaaaaa agaatcgaaa gtacagccat
    57241 gcgcatttct ttttatacgc tcttcgataa ataccattcg ttcttcgatc gttgtgtcat
    57301 cgggcgtgat cgttttttcc actttttgag aaaatttctt acgttctaag attttctgca
    57361 tggcacggat caaatcgatt tttttgactt gtcctcgctt caacggcttt tcagcatccg
    57421 ctaacccatc gatgttcata ggttcttttg tgtaataaag acttcgttcc tctgcttttt
    57481 ctgtcagtct ttcagctgca tatttatatt tacggtattc taaaagctga gtgaccaatt
    57541 cttctcgagg atcttcttcc cataattctt catcgtctgt gacgaattct tggacaggaa
    57601 gcaatgtctt gcttttgatt gccatcaatg tagcagccat cactaagtat tctcctgcaa
    57661 cagctagctc gagtgttttc attgtatgga tataattcat atattgctcc gtgatcgtag
    57721 cgatcggtat atcatatata tcgatttcca tttgctgaat cagatgaagc agcagatcga
    57781 gaggaccctc gaatacatct aatttaatat tgatctccgt caactcattc actctttctt
    57841 ctttttcttt gctagccatt ttccaatgta aggctctgtg atttcagttg cacggatgga
    57901 gacatccggg tacttttcct gtaattcatc taacatttga aagcccatat tctcaccgcg
    57961 ataagacgga ttcaaagaaa tgtcatggat gatcagctga tcgttcgttg cccagtaaat
    58021 accaataatc ccttgaatgt tggttgaacc ttctggcgta aagaaaaaaa gttcataatc
    58081 gtcttcagat tcgtacgtat caatctcctt caacaaagaa gttttacctg tcagtttctt
    58141 atggaaactc aatagtccca tagcaatttt acggttttct ttccggtaat gtgttaacat
    58201 cttctcacct tcctatgact aagcccttgg aaaatgctgc ttataaacat ccgtcattct
    58261 tttcttcgtg atatgtgtat aaatctgagt cgtagagata tccgcgtgac ctaacaattc
    58321 ctgtactgtc cgcaaatcag ctccattttc tagcagatgt gtggcaaagc tatgccgcag
    58381 cgtatgtggt gttacttctt tgtaaatccc agcctctcgt actaactgct tcagattttt
    58441 ccagattcct tgccgagaaa gacctttccc atgattattg acaaatacat gcatttcaga
    58501 tgcgtccttt acaagtaatg gacgtgcttc gtctaagtag cgttccagcc attggatcgc
    58561 ataatcacct aaaggaatga tccgctcttt atctcctttt ccaactgtct gtaccagtcc
    58621 aagagaaaga tgaagatctc ccaatttcaa tccaatcaat tcactgacgc gcatcccagt
    58681 agcatacatg acttccaaga ttgcacgatc tcttatccct aacgtttttg tcgtatcagg
    58741 tgcttcaatc agcttttcta cttctgtcag agtcaatgta cttggtaatt tctgtgcttt
    58801 cttcggcgta tcgatatgtt gcatcggatc atgatcagtg atacgctctt gccgtaaaaa
    58861 ctgatggaat cttctgagac ttgagatcat ccgagtaaca gttgctgtcg cttttttttc
    58921 ttcatgcaac ttctccagaa aacggatgac taaaaagcga tcgacatcct gccatgaagc
    58981 aattttctgc tcctgtagaa aatgcaagta ctgttccaaa tcacgttcat agctttgtcg
    59041 tgtattggcg gacaatcccc gttcaatatt caagtagtgg agataatcgt tgatttgctc
    59101 tttcataata atccccctca tgcctctcta tcatatcaga taccgcttca ttctgatagt
    59161 ctttttccat aatctgagca aagaaaaagc cgtctagaca ctcagacgga ctggtttctt
    59221 ttttcttttt catagcattc ctgacagatt ccatggaacg ttagccgatg atcttttact
    59281 aaaaaatgat aacgttcttc tactacttgc tccacttcaa gtaaaagatc ctcttctact
    59341 tcctcgatcg tgccgcagtt caagcatagt aaatgatgat ggaaatgttt ggcgccttct
    59401 tttctcaaat cataacgggc taatccatca ttaaaactta ctttatcgac aattttcaat
    59461 tctgtcaaga tttcaagggt tcgataaaca gtagcaagtc caatttccgg actctttttt
    59521 ttcactaaaa agaagatttc ttctgcagat aaatgctctt tctcattttc caaaagcaca
    59581 agcagagtag cttctctttg cggtgtcagc ttaaaccccg cttcatgtag ctgctgtttt
    59641 gtttttttca tcgccgaaat agcattcatg accatttact caaccccaac aatttataat
    59701 aattacaaat aaaaaaagat ataacactat gttaattaaa attattataa gctagttaag
    59761 aaaaacatgc aagggattct caattagatt ttttgactag ttttgtcaca ccgttttctt
    59821 gtgtaatcaa tccttgtttc aaaagattac ctaatgcgcg cttaaatgct cctttgctga
    59881 taccaaaagc tttcatgatt tcttctggat ccgatttatc tgtaaagttg atttgctgat
    59941 ctgcagaacg ttctaaaatg gttaaaatca tttgtgcatc atctgatata gcttcatatg
    60001 ctcttggctt caatgaaaga ttcagtacac cgtctggtcg gacaccaatc actcgacctt
    60061 ttatctgctc gcctagacga ggttcattat atcgttcaga aggatggata aacccaagat
    60121 agaaatcttc cgttaaaacg tacgtacctg ttaatttcaa gcggtatgct gttcctatca
    60181 catctttgtt tttcatttct tctgttccat atttgcttaa agatttgaat attttttcat
    60241 ctgctaaact gccccaaata cggtcttttg catcaactct aagggaaatc atcaagcgat
    60301 cccctttttt aggccatagc tctgtcattg tcggcaattc atcaagagat acgacaaagt
    60361 ctttatctgg aagaccgata tcgacaaacg cacctaaatc ttttcgtgta gcagtaacga
    60421 ttccaaaagc gtaatgaccg atacggcttt taggaatttg tgtagtgatc cgattttcat
    60481 gtttttgatt ttggtaaccg aatccttcaa ctgcttcacc gattttgtgt tcaccttctg
    60541 atttgcttaa gccaaaggtt tgtccgtttt tttggacaaa gtagtttttt tcattttcat
    60601 caataataat acctgtaaat atagttgcta ataaatcgtt catttttttc tccctctata
    60661 gtgaaaggtt ttcttaatac atttctttgc tatcataaca taatgttatc tacttgaata
    60721 gctgagcctt ggtttggaaa ggtgaaaaaa ggagtatgac aacagttgtg tcatactccc
    60781 ctttttcgaa taaacggtgt taaacggcag gctcacagcc tctttcattt gcctaaaatt
    60841 aattgctccc atttcctccg aaccatccag ttttacagtt gatggttacg atgtaaaatg
    60901 gcaaagcact ttctccaatg cctttcatca atgcagattt tgttgaagtg gcatatagat
    60961 tataatagcc ttccccattt tcgattctgg ctttttctaa tctgtaacct ccttcaacga
    61021 tatatccacg ttggatacat gtagcaatca ctttgctttg gacacctggt gcccacgtcc
    61081 atgctggatt agatgcatcg gcaatatcac ttgctctggc agatttgatt ggctgattcg
    61141 ctgagtttga agaggaaggg gtcgaggatg ccgcttcttg ctgtgctgct tgtgcgaccg
    61201 cagcttgttg agcggcttga gctgcagctg ctgcttgagc ggcttgtttt gcttgttctt
    61261 cagctgcttt tttcgcttct tctgcttttt tcttttcctc ttcttctttt ttctctttat
    61321 cagtgagcat cttatctact tgtttcaatt gttcattcaa ctgagcagat agatctgtat
    61381 ttttcacttt ttctactgct tcttttgccg tcttgtattg gtcgcgtgtt gctgaatcca
    61441 ctacttttcc gtctttaaag actatagctg ttttttcttt agctgtttgc aattcagcat
    61501 attgattttt agcttctgtt tgtgcttgtt gaatcaattt tccaaaatct gtgttatccg
    61561 tttcgattgc ttggatctct ttatctgctt tcaacttgat gtcatctgct agatgatcat
    61621 cgacgatggc aggtgctatg aaccactcat tcactttttg gatatctcgg atcttagatt
    61681 ggatatcttg gtaagttgtt tctaactctg aatatccttt ttcattctta agactggata
    61741 aatcattttt tagttttgat aaatcttgat gaatcatatc tgcacgaata aattgatggt
    61801 gatcatctgt ataaaaggca gcaagtttct catgaagttc ttccatttgt tgctgtcttt
    61861 ttgcttctgc tgctacttcg gcttctactt tttgatgatg gtcataataa gcccagcttc
    61921 ctccaccgag tagaagtact gctgctaaaa cgagataagg tacttttttt gattttttct
    61981 tttgcgcttt atctggatct gttttttcta agtttgattc ttgatgtgtt ttttcagtat
    62041 ctggcacgat tgttattgat ttcgcttctg cttcaaacag cttaggctgg ttctcttctt
    62101 tttctatttt tgcttcaaga tcagtaccct ctttgcttac agattgattt tcagcatcgg
    62161 attcactatt tatttcatcg ggctctgttg actttttgtc tgtgttttcg agtatttctt
    62221 ttttctctgc ttccggcagt ttattcgttt tttccttttc taattgtttt tcagtaaata
    62281 cttcagtttt ttctgtgata tccgttttta cgtcttttat ttttactgtt tctttacctg
    62341 tggcgttttc tctatcagag tctttttcag tttcttgttc cttttctggc tctactttgt
    62401 tttcctgtgc aattttttca ctgatcattt tgagcagctc tttcgcgtgc tcttcttttg
    62461 tatcttcacg atgtgctttg atataagcgg atagtatcga attttcttcc tcattatcga
    62521 cgatttcttt cagttcagct actcttcttt tttgttttga ttcaagcgtt tcttcttgat
    62581 tctttcctga ttcttccgaa gtctcatgaa cagttgcttt cttctgttca tttttctcta
    62641 tattagttac ttgatcgtga gcaggtggtt cttcgtcttc tggttctgct ttttcgaata
    62701 attccattac agattctaga ggtaaatctt tcaattccga ccattcgatt ggatcgttta
    62761 attctgtatc aggaaagact gcatcttcag ttgatttatc ctgcatagct gcatctgtat
    62821 ttgtttcttc aattgattct tttatttgct gatcttctgc agttatttga tgaccgcagt
    62881 ctggacagat agtattctgc tccatttttt tcgatccgca atttggacat tttttcatca
    62941 cttagcgatc ggctccttta ctaggtttac gctaccattt aatctatcat attctatacg
    63001 tcacgccaat agcttatttt taggatttac ttaaaaataa tgaatgaatt tccttcctat
    63061 agaaaaaaaa gcttgagact gcgtagtctc aagctttttt tcttttaaaa taaaccaaac
    63121 agttttactg atttctcttc tggtcaatag tccacgctta ttctaagaaa tcttttaatt
    63181 gttttgaacg agaaggatgg cgcaattttc ttaatgcttt agcctcgatc tgacgaatac
    63241 gttcccgagt aacaccaaat actttcccta cttcttccaa tgttctcgtc cggccatcat
    63301 ctaaaccaaa acgtaagcga aggacattct cttcccgatc agtcaatgta tctagtacat
    63361 cttccaattg ttcttttagt aactcataag ctgcgtgttc tgctggactt gttgcttcct
    63421 ggtcttctat gaaatcacct aagtgagagt catcttcttc accgattggc gtttcaaggg
    63481 aaacaggttc ttgcgcgatt ttcaagattt ctcggacttt ttctgttgga agatccattt
    63541 ccgcaccgat ttcttctggc gtaggttctc ttccaaggtc ttgcagcaat tgacgttgga
    63601 tacgtatcaa tttattaatt gtttcaacca tatgaactgg aatacggatc gtacgtgctt
    63661 ggtcagcgat tgctcgagtg atggcttgac gaatccacca tgtagcatag gttgaaaact
    63721 taaatccttt gcggtagtca aatttttcaa ctgccttcat cagtcccatg tttccttctt
    63781 ggatcaagtc aaggaactgc atgcctcgtc ctacataacg tttagcgata cttactacta
    63841 aacgaaggtt tgcttctgcc agacgctgtt tcgcttcttg gtcgccttct tcgattttca
    63901 atgctaacgc tacttcttct tccgcagtta aaagggcgac acggccaatt tctttcagat
    63961 acatacgaac cgggtcattg atttttacac cggttggcgc agaaagatct tctgtttttg
    64021 cttgttcagc ttttttctca gcactcttca agctgtgaat tgatggatca ccattttcat
    64081 ccaccacact gatacctgcg tcttcaatct tttggatcaa tttgtccatt tcatctgcat
    64141 tcaaagtgaa tggtgtagca agctgattgg ataaatcatc atatacaact tgtcgtttgg
    64201 gtttgttttc tttgatgaaa gctgctactg ctgcttcata cgttttttta tctgttccat
    64261 ttgccataaa agaaggcccc ccttgagtag ctatttggct tgttttaact gtttcgttaa
    64321 attgatgatt tcaatcgtca attcaagctc aagctgtttg tttccagttc gtctggcttc
    64381 ttgctgcatt tgttttttta atgttatttc atcagctaag ccagatttgc tgatcacatc
    64441 tagcaagtct tggatttctc gtggcgaact ttcttctgcc accggtaaat attcgatttc
    64501 caccaccaac cgccttaaat tttcatcttg caaaaagtct aaaaactctg caaggttgaa
    64561 ttcataatgt tgtgagacat atgcatcgaa taaaaaataa acttctgcat atgcatcatg
    64621 aataaactga aattctcgtt cttttaaaat attacggaca gaaacttctt taaatgcacg
    64681 atataataga atctgctctg ccttttctac ttgcgtcaaa ggtctctttt tccgtgcagt
    64741 ttcttgtctc gtaacctgag tgtgttgact ttcctgaggt tcttgacgat tttgctgatt
    64801 tgtccttcga agatcgcgca gttgtttttg tatcgtctct ctgccgatct gaaactctgt
    64861 tgacagttga gatagataca tatcttgttc gattggtgaa acaactcggc taagttcaac
    64921 tagtaattct tcgaggtatt cgatcttgtc tttttcatta tctaaatttt tcccttgttt
    64981 taaataacgt gatttaaaag taaagactgt ttcgcgccca tgagccacta attcttggaa
    65041 agatgcttct ccatacttac ggagatattc atcaggatca agcttttctg gaacgactac
    65101 gacagaaagt gctaatcgac tgttttgccg aagcaattca atccctcgat tggttgcttc
    65161 aaaacctgcg ttgtctccgt catagcaaaa gaccaattct ttcgtcagct tttccatttg
    65221 ttggatctgt tgagctgtta gacttgtccc catagaagct aatccagttt tgataccagc
    65281 ctgccatgca gcaatcacat ccataaaccc ttcgaacaac aaaatttctc cgtttttccg
    65341 gatatcgctt cttgctttat caagattaaa taaaacttgt cttttattga acagttctgt
    65401 ttctggacta ttcaagtatt tgggctgatc tttttcctgc cctttttcag gtgcaagcca
    65461 gcgtcctgaa aaaccgatcg tctggccttg agaattacga agtggaaaca tcactctttg
    65521 ataaaaacga tcagacatac ggccatcatc atgcgtgaca aacaatccag agcgttctaa
    65581 caattcattt gaaattgatt cattcttgaa tacttgctga agaaaagaac gctcattagg
    65641 tgcaaaacct atgttgaatt cttcaattaa ttctaaagac aacccacgac tttgcaaata
    65701 ttctaaagct ggctgtccag cttttgtatg caatagcatg tgatgataga tttccgctgc
    65761 tttttcatga gcagcaatca gtttccccgt agcagattca ggattttgga cagctatagt
    65821 acgctgacgc cattgatctt ctaacggtat ctgttcgaag tctgccactt ttaccactgc
    65881 ttctggaaaa cttagacctt ctagttcttg aagaaaagta aacacgtttc cgcctttacc
    65941 acaaccaaag caatgaaaaa tctgcttgtc ttctgcaaca gaaaaagacg gtgtacgttc
    66001 ttcatgaaaa ggacacagcc ccaagtaatt tttaccagac tttttcaact ggacatattg
    66061 tccaatcacc tcaacgatat tcgtttgact gcgtactgtt tcgataacct cttgaggaat
    66121 ccgttgagcc attttttcac cccctgctct attgatatct tttgggttta acagaagata
    66181 tttcaggaga ataaccggta aaaaatcgca ctaactgaaa tcagtgcgat tttaaaggac
    66241 acaattatac atgtttgatt gtatcatatt tcattgcttt ttcaagtata acacatttct
    66301 atctcattaa gcatcaattt gctactcttt tcagtaactg attttgaata tcagccttcc
    66361 agtacaatac tcgaagaaca atatttacga gcatgaatac aaagaagtat cctacgctct
    66421 ctcccaaccc taagtttact tccaaaattc catggaacag cattgcagct acatatatcc
    66481 ctacgatcgt cgttactgct aggaagatgc gcaatgggtt gaagggataa caagctttta
    66541 caactgccat gcaactgatc ccaatcagca agtaatacat caaagtagta gtttcagcat
    66601 ttccccatgc gaatgttttt ccaagtagat acaccgcaat gatattcact actacaagca
    66661 aggcatttgg taaagcatta ataagtgctg taggcaaata acggtaagtg atttttcttt
    66721 tatcttgttc aaaagataaa aagaaggaag gatacccttc aatcgctaaa tcaatcagcg
    66781 tgatttggat agggataaac ggaaatccaa ttgctgtaac ggcacatata atcgataaaa
    66841 taaatgaata aatcgttttg ataaaaaaga tgcctgagac tttcgtcaca ttgttgacca
    66901 ctcggcgtcc ttcaaacagg acttctggca atgtagtaaa atcagagtcc aacaatacca
    66961 gattcgcaat ctgacgtgtt gctccatcac cttctgccat agcaatgctg caatctgctt
    67021 ctcttaacgc caaaacatca ttcacaccgt cgcctgtcat tgcaaccgtt ctgccgcttt
    67081 ctttcaattc atttaccagc aatttctttt gctgcggact cactcgtcca aaaaccgtat
    67141 agcgatgagc agcttctcgc acttccattt cttcagtaat ttgagaaaga tcgacatacg
    67201 catcataatt cggtaatcct gcacgtctag cgatattgga gacagtaaaa ggattgtctc
    67261 cagaaatcac tttcagatcc acaccttcct catgaagata agctagtgtt tcttgagcgt
    67321 tttttcggat tggatcatcg atttcaaaca gagcaaccgg ctcaacaaat gctggttttt
    67381 cttcgttcaa ttgctgattt ggagcgatcc ccaacataag tacgcgatag ccattcgctt
    67441 gggctgtttt tagactgtcc ggaagccgat cttcttccac caaacgttca ggcgctccta
    67501 cgtacacgac tcccagttct ggaaattcca tcgcgcccca tttgcgatca gaagaaaatg
    67561 cgactttgtt tgtcacatca taccgattag aaagctcaaa ataatctctc atagcccgca
    67621 tagtgatgtt gttatcactg ctttctgcca gatacgtccc cataatttct gggatggctt
    67681 tctcgtacag cggatgtagt gcttctaccc gctggatact cattttccct tcagtaatgg
    67741 tccctgtttt atccaagcat aatgtatcga catgggccag cgtttcaatt gaatacatgt
    67801 cttgaacaag gattcgtttt tttgccagtt tggttacccc tgtcgttaat gcaatactta
    67861 ttagcaatac caaacccttt ggaagcatgc ctaacaaagc tgctgcagat gcaataacag
    67921 aaattttgat agaagcatcg cggatgaaca gtgcttccaa aaatagtatg atccccaaag
    67981 gaataatcac gaaactagtg aatttggata ctttgcgaat cgaatctaca agttcagaac
    68041 gaatagcttt gtgagtcttt gcctcgctag tcaagcggac agcataatta tctgcaccta
    68101 ctcggataac ttcagccatg acagaaccgc ttgtcaaaaa gcttccagaa agcaattcag
    68161 ctccagtttc tttgacaatc aaatcagatt cgcctgtcaa aagagcttca tttgcttctg
    68221 cccgtccaga tataacctgt aaatcggctg gtatctgttc tcctgctccg atttttacca
    68281 aatctcctaa taccagctct ttagtagaaa tcgattgttc tttaccgtcc cggatcacta
    68341 gtacttctga ttgggaaaca atcgataatt tccgtacaag atttcttgca tgtatttctt
    68401 gataaattcc aataacgata ttgacgacaa taattgctaa atacgccatg ttggaatacg
    68461 cacctacaaa taacagacaa atcccaatac caaagttcag aaaattgaat aacgtcaata
    68521 tattatcgct gaatatttgt tttgtacttt ttgatgcatc ttcctggtag tcattttgct
    68581 ggccagaagc cattttctga actacctctt gctgtgtaag tccattcatt ttctttttct
    68641 ccattttccg ccaactttca aaaataatca cgtgtttaag tctagcgtgt tccaagatta
    68701 aaaacaactt gtttttataa aatttataga aaaacacacg aatgatttta caaaaaagat
    68761 gccaaccttt ttgtttgaat cacccgtgtg ctgtttttat tatcaatcta tctttactta
    68821 tattgttcct ccaaacggct catccaccaa cctagtgctg taccggctat aaaaagaaca
    68881 ggacaagcta gtaccccagc aactcccaat cccgcgtaat cggtaggaat gatcataatc
    68941 gttgaagcaa aaactacacc taaaatgaaa tggaatagct tgctatatgc ctttgagaaa
    69001 atgtaatcca tgatttttga caatccaaga acacaaagaa tcccaccaat tccgatcggc
    69061 acaatcactt caagtcgtac ttctttaaat ccgtcagcca tcgctttata caatcccata
    69121 tacaccaaaa aattagaagg gctcaatcct gggacgatca tacccaaacc aatcaatccg
    69181 ccggcaatca gccatgttcc aaaattctga tcgacttgcc cgtcaaataa ttgagcgccg
    69241 tataataaaa acaaataagc cagaacaaaa gtaacaacca tgatgatcac atcagaagta
    69301 tctcttcctt ttttccctgc ttctttccat aacgcaggaa cagttccagc gatacatccg
    69361 acaaaaaacc ataatatcgt tgtttcatac gcacctaata aaaaactgac taaaaaagaa
    69421 agtagaaaga tgcctgtcac tccgcctaga ccaacaggca gaaaaaacaa aacattttct
    69481 ttgaaatttt ttgtaaggtg ggctaaaaaa gaaatcagcc gctcatacat gccaaagaca
    69541 gctgctaatg caccaccgct gactcctggc aagataaatc ctgaaccgat aaacattccc
    69601 ttcacaaacc gtaacatcca gtctttggtt gtgtacccca cttcttgatt ttccattttt
    69661 tgcctttttt ccactatttg cgtactcctt ctttcattta attttattca tgattgaaca
    69721 tttcctgcta ttttacttaa agactttttc ataggtctct attatttttt cattcatttt
    69781 gacaatatca ggataaaaca tgttacctcc attatgatag agatagccgc cattgtaaag
    69841 caaggactgg atccgccaat atcggtattg tttcccttcc tcatttccta aaagtgggct
    69901 cagcacatct ttagaatacg cttctgctaa ttctactgtg ttttctccgc catgattttt
    69961 tacataggca atataatctt tcccaaaatt atatgcttgg acagctgtcc ataaatcgca
    70021 tccttgtttc tttgcttcta ctatcatttc cgccaaatat ttgacacctt gatcaatact
    70081 gtcagctgga ttatcaatga tctcagcttc tccatgcaga ctttccgagc tctgcatgag
    70141 atctgtccct tttccttttg attcggtcaa tattatcgcc ttgatcaaat tctcgtagtt
    70201 ttccatatga taattttttg cagctgttgt tatttctatt tgatagcttt ccactcgttt
    70261 taccgaacga taagttcttc ctcataaaaa caacaccgca ccaataaccg tcagaatgat
    70321 catgtaaaaa agaatacgga taatagataa tcgttttcgc ttcatttcat cacctagtta
    70381 ttttgacatc tttttttatc ttactatttc tttatcttct tggctatttc ttccttgatt
    70441 tctgtgtacg ccttaagaaa aaatgaattt tcctgtattt tttgacatct tacgaaaatg
    70501 atcgttgttt ttcagtaaaa acaattgccc aatgactgat ataatcgtta tactttacac
    70561 agtaggtgat tatgtgaaaa aagaaaagaa atatgcaaaa atgccagatg ggagcgaaat
    70621 ttactatgaa aagagcggtc aaggcttccc tctcttttta ctgcatggca atgacggcag
    70681 cggccgcttt ttttcagaac aggtccctgt actcgaacgc tactataccg tgtatctagt
    70741 agatagccga ggacatggtc gttcgacaaa cgaagcatct atgttgaatt ttcagttaat
    70801 ggccgaggat ctgaatacga tcatgttgct ggaaaaaatc gatcaggcag attttcttgg
    70861 atttagtgat ggagcaaatc tagcactggt atttgccagc agcttcccta aaaaagttca
    70921 tcgattgatt ttaaattctg gaaacacgct tgttaaaggc gttcgttttt ctgccagagt
    70981 catcagtaat attcattatg catgggtatg gttactctct ttatttcgcc caagtcttcg
    71041 caaaaatctt ttagttatca aacttttgct gcatgacatc gggcttacag aaaatgattt
    71101 aaaaaaaatc aactccccca ctttgatcat cgtgggaaaa aaagatgtaa tcaagctaaa
    71161 acattctttg tatatagcta aaactatacc aaaagcttcc tttgtgcttg tgaaagaaca
    71221 aggacatgaa ttagctagaa aagatcctga acgcttcaat cgagaagttc ttcaatttct
    71281 ttctgaaaca taactattag gaatagaagg tgatttattt gttaaaaaat accatacaat
    71341 ggctgaaaaa ccacctagga ctgttcaaaa caatcttttt gatttctgtc attgtcatta
    71401 ttgtcggtga attgatgtcc atcggtaaaa ctctatctat ccagcaatta ggagaaacgt
    71461 ttgccactat acctgtatgg aaaagcggac taatgctatt gattggtctt atctctgtgt
    71521 tacctatggt tggttatgat attattttga atcggatgct tgaacaaaag cagaatcctc
    71581 gttacctgtt tgagacaagc tggctgatca atacgatcaa caatattgcc ggtttcggcg
    71641 ggtttgttag tgtggggctt cgctctgaac tatatggaca aaagaaagag agcagaaacg
    71701 tgatccaagc attatcgaaa gttttcttgt ttttgatggc tggactttct atttacagtc
    71761 tgctttcttt tttacttgta gtcttcacgc cagttgctcc ttttttgaag caatattgga
    71821 tatggttgat cggcggcggt ctatattttc ctgtcgtctt tttatttact actttcaaaa
    71881 agaaaggatt ccttggtggt acctcactta aaactcaagg acagctattg ctagtttcat
    71941 tgttggaatg gaccggtgtc ctgtttagtt tcctttctgt tggttattta atggaaatcc
    72001 ggattgatct gtggcaaaca attccattat tcattgctgc ttcagtgata ggaatcgtgt
    72061 ctatgattcc aggagaaatt gggagtttcg atgtaatgat gattatcggg ttgtccgcta
    72121 ttggtgtgcc aagagaaata gtcgttgtgt ggatcttgct ctatcgcctg ttctactaca
    72181 tcattccgtt tttgattgga atcgtctttt tcttcaaaaa tatcggttcc acttttgatc
    72241 agcgttattc tggtatccct aaacaattag caacagaaat tgcgcataaa atcgtggttg
    72301 tcttattata cttttctgga atcatgctag tactttctgc cactatcccg caagctttta
    72361 cagagtttcg ctggcttcat agtttgaacc cattgaaatt tcattttatt atccaatttc
    72421 ctagtatact attgggattt cttttaatca ttatgggcag agggatcgca gcacgtgtga
    72481 aacgagcata tttgcctaca atcttcttga ttgttctagc tttactttat gttttattaa
    72541 gtgattttag tttcacaccg gtggttttct tgtctattct gcttctgatc attcttgctt
    72601 ctaaaaacga attatttcgg gaacaattga tctattcatg ggagtggcgt acgatcgatg
    72661 gaatcattat tggtgcactg tccttgcttt acatcgttat tggggtatac aatctgccgg
    72721 atttccctca tcggcgtcac cattttattt cctttttctt atttccttct gaaaagattt
    72781 ggttttcggg attgttggcc atcatcgctg ttagtttcat gatcgttcta tttgttcatt
    72841 tccttcaagg agaaaagaaa cagattggcg aagcctttaa tgaagaaaag gccctgaaga
    72901 tccttacaac ttatggagga aactccgata gtcaattgat cttcttaaaa gataagcgga
    72961 tgtttgccta tgaaaaagac ggtgaaccaa ctgttcttct ccaattcgct tgcttcaata
    73021 ataaatgtat tgtaatgggt gatccttctg gtaagaaaga agattttcca gaagcaatcg
    73081 aagcttttat cgaagaaaca gatcgactat gctatttacc agttttctac gaaacaagcg
    73141 aagagattgt tatgattttg catgaattcg gctacgattt cattaagatg ggggaagaag
    73201 cttatgtaga cctgaatagt tttacaactt cagggaaaaa aatgaagggc actcgtgctg
    73261 tcttgaatcg gatcgaacga gaaggattta catttgatgt cttacaacca ccattttcta
    73321 ctgagcaaat gagtactttc aaaaatatct ctgataattg gttgggttca cgaaaggaaa
    73381 aagggttttc tttaggcttt ttctctgaag attatctaca aagagcgcct attgcagttg
    73441 tcaaaaatac ccaagaagaa attgtcgctt ttgcaacgat catgcctact tacacgaaca
    73501 ataaagtagg aacgattgat ctgatgcgat atgattctaa aaaagcacct tctggcagta
    73561 tggatttctt gttcttgcat ttgtttgcct atatgaaaga agaacatatc caatggttca
    73621 atttagggat ggcccctctt tcaaatgtcg gaacttccag aaagagtttt ttacaggaaa
    73681 ggattgcata cttggtttac gagtttggtt ctcattttta ttctttccat ggattaagag
    73741 aatataaaag caagtacgct acaaactggg tctcacgtta tactctatat tctagagata
    73801 gttggattgc atatgttatg attgctttgc tgattattga taatgcgcca gttgagcaga
    73861 cacaaggtag aataagtggt ttgaaaaaat ggatacgaag aaagtattaa aaactgcata
    73921 ccgatagatg aacactctca tgatgaataa aagagactga agtaaaacga aagttcatgc
    73981 ttctacaatc tcttcttata caattgaaga acaaagagcg gtccaaacag aaatcctgtt
    74041 tggaccgctc ttttatttta aacatttttc attaccaaaa tattcgagtc gcgtttctta
    74101 tgcttcgatc tctgtaacga tacctgaacc tactgtccgt ccgccttcac gaattgagaa
    74161 tgtcgttccg ttttcaacag cgattggatg gatcaagtca acatcaatcg tcacgttgtc
    74221 accaggcatg accatttctg tatcttctgg caatgtgatt gttcctgtaa catcagttgt
    74281 gcggaagtag aactgtggac gatagttgtt gaagaatgga gtatgacgtc caccttcttc
    74341 ttttgtcaac acgtacactt ctgctttgaa ttttgtatgt ggagtaatgg aacctggttt
    74401 agcaagtact tgtccacgtt cgatatcgtc acgttggatc ccccgtaaca acacgcctac
    74461 gttatcccca gcttccccgt aatctaacgt tttacggaac atttctacac ctgttacaac
    74521 tgctttttgt gtttcaggtt tgatccctac gatctctacc tcatcaccga cacgaacagc
    74581 accacgatca atacgacctg aggcaacagt tcctcgacct gtaattgaga agacgtcttc
    74641 cactggcaat agtaatggtt tatctgtatc acgttctggt gttgggatat attcatctac
    74701 tgtatccatc aattccataa tagcagcttc agcatctgga tcgccttgca atgcttttaa
    74761 tgcggaacct ttgatcacag gagtgtcatc gcctgggaaa ccatattcgc tcaataactc
    74821 gcgaacttcc atttctacca aatcgatcaa ttcttcatca tcgactaaat caactttgtt
    74881 caagaaaaca atcaggtatt ttacaccaac ttggcgtgac aataaaatgt gttcacgtgt
    74941 ttgaggcatc ggaccgtcag ttgcagaaac aactaagatt gcaccatcca tttgtgctgc
    75001 ccctgtaatc atgtttttca catagtccgc gtgtcctggt gcatcaatat gcgcgtagtg
    75061 gcgtttttct gtttcatatt ctacgtgtgc ggtattgatc gtaatcccac gttcacgttc
    75121 ttctggagct gcatcaatac tagcatagtc ttgaggattt gctaggcctt ttttgcctaa
    75181 tactgtagtg atcgcagcag ttaaagtagt tttcccatgg tcaacgtgtc caatcgtacc
    75241 aatgttaacg tgtggtttac ttctgtcata atgttctttt gccataattt acaaacctcc
    75301 taaataatat agatcactga aaaatttcag ctctcacctt tttattatag tctttttttg
    75361 actaaatcaa aaagaatacg tccgacttac tttttgtaag attcgaacta agcttattat
    75421 acgtcaatat tggtcaaagt caactaagag cactcgtctg tcttatacgc gaaaaaagta
    75481 ccttttataa ataaaaaaat gtgttttttg agaaaaactt caagatagtc cttaactttc
    75541 ttttgaagca ataagaacaa aatgaggaaa agtttaaaat tcagctgttg ccaacaactt
    75601 tcaatagacg aaatcttcta tttcgttaat aataaggaaa gaggtgaagt acatgaaaaa
    75661 attaattggc gtacttgtcg ttttaggcat atttctcggc ggaagttttg cagcttatca
    75721 ttatttttac ggcggcgaag cttattatac aaaaatcacg acgaatggcg aaatgtcagc
    75781 tacccaagca gataacggag agaaattcac gacttatacc tacaagcaag cggcttataa
    75841 taaagatggt gaaaaaaaac aggtgacgct tcgcgaagaa agagaacatc cattaaagat
    75901 gaatgcgtat cttaaactca aagtcaatcc tcgtaaaggt gtattaagct gggaagaaat
    75961 aaaggcttct gaagtgccta aaaatgcggc agaaaaaatc gataattagt aaatggtctt
    76021 aaaattttat tagataaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    76081 gagttgcttc tgcttccgcc gtttatacgt gtttagagcg tgagacaaaa gtgttcttta
    76141 cttttgtctc acgctctttt tttgttatat tcgtcttttc cgatccttct cttgacacaa
    76201 ttcatttaac tgatcactgg tacttgaaca cctaatattc tagtcatttt tataaacgat
    76261 tcaatacttc atccacattt ttgatcatca cggatatcgt accatccgga ttattcacaa
    76321 attcaatcaa atctgggttg cgatatacat ctactggtac gatcagttcg atcccgtttg
    76381 atagcttgaa tttttgtttt ccaaattttt tctcagaaat ttcttgtact tcttttacag
    76441 gaggtgcttc tgggacaaat ccttgctctt gtacttcttc tttaaaagcc atttttgccg
    76501 tgatgttttc cttgaagact ttttccgcaa tcatctcatg atccaaccga cctttttctt
    76561 ctatcgtatc atagacagct tctttcaaat cagccatgat atcaaattct tctgtctcaa
    76621 atttttttcc aagatgcttg gctacttttt ggatcacttt tacattttct tctaaagaag
    76681 gtgcaggaac actttcgatc actcttccag aaaaataaag ctcttttttg ccagaaaact
    76741 catatttttt ttcaattaat tcgtaggtcc aatcagtcaa attcacagcg aatgcttcat
    76801 ctgctttttg tgttttcgcc cctagaattg ctcgattcaa aatcaagcgg ttgtcgatcc
    76861 ctgcttcgtc tgcttcaaca aagtgagtgt aagcctcacg ataattgact ttcaataaag
    76921 ataagtacat cactgtatct aattcataca agacaacaaa tacatctgca ctaggtgctt
    76981 cttcactttc ttggtagata tcgaaccacc gctgaacgat tgcttcactt gcttccacaa
    77041 aattttcttg agcgatttta agtgattcaa cgatcatgct ttcttctgct agttgtccag
    77101 tttttgtttg agcagaagag attttttgga tcttcttttg aagaaaatca cgaatatatt
    77161 cttttgtcag atccagctct ttttgtgaaa agactggaga accagtttct ctgtcaataa
    77221 tatgcagaat tgcttttttt aaatagatat ccattttctc attcccttct gtcttagttt
    77281 acggaaaaaa aatcaaaaat accagaatca aaatcatttt cttttaaaca aaaatttcaa
    77341 gagtagaaac aaaatggatt ctttttttcg aaaaatgcgc tacacttata gttgaacgaa
    77401 taaaaaagga gctgaaagta tgaattcatt aacaagcact tatcgtctat caaatggtta
    77461 cgaaatcccg gtagtaggat tcggcacatg gcaaacacct gatggggatg tcgctgtttc
    77521 ctctgttaaa gaagcgctgg ctgcaggtta tcgccatatc gatactgccc aaggatacaa
    77581 gaatgaagaa agcgtcggcc aagcgattaa ggaaagtgga attcctagag aagagatatt
    77641 cttgacaaca aaattatgga atgcaaacca cagctatgaa cttgtgatgt cttcttttga
    77701 agaatcattg aagaagctcc aaacagatta tttagatctg tttttgatcc actggccaaa
    77761 ccctgttgct tttcgtgata attgggaaca agcaaatgca gatacatggc gagcatttga
    77821 agaactgtat gaagcaggta aaatcaaagc aatcggtgtg agcaatttct taccccacca
    77881 tctagataca ctagcaaaaa cagcaaaaat tatgccgatg gtcaatcaag ttttccttgc
    77941 accaggcgaa ttacagacaa ctgtagttga gtatgcaaaa aaacatgata tgatcctcga
    78001 agcatatagt ccattaggca ctggtaaaat cttcgatgtg cctgaaatga aacaaatcgc
    78061 tgaagcacat gacaagacga ttgcacaagt tgctttgcgt tggtcgctgc aacacgaatt
    78121 ccttcctctt cctaagtcag tgacaccaag cagaatcaaa gaaaatactg aattatttga
    78181 ttttgaatta acagaagaag aaatgaaaca aatcgatcag ttagatggtg tagtcggcaa
    78241 agcaaaagac ccagatacta cccaatttta agtcgaaagg tgattttatg gatccaatcg
    78301 aacgcttgaa ttctctctcg gaagaagtta cccagacttt tcattccgat tttgtctttt
    78361 tgatcgatgc agagaaaatc caacattttc ctgcaagaaa ctggacacat gatcaaatca
    78421 tcgaagaact gaaaaaacgg ttcgatcatt cgctaatggt caaaccctgg cacgaacatg
    78481 aagtcattta ttcacctgaa ctacctgttt ttgccttgat accgaaaaaa tagaaagaat
    78541 ggaacggatt atgtatatat acataatccg ttccattttt tatttttctt tcaaaaaacg
    78601 ggaaaatacg caaatttttc tgttgtaatt tgcgtatacg caagtttttt tgcattactc
    78661 cttttcattt ggctgttttt ttcttataat cgaaagggta tgagcgaagg agagaacata
    78721 tgaagaaaaa acagaaacaa aaattattaa atcaattccg tccttcattg gatggtgtaa
    78781 gaggacaatt attccgttct ctagaagaag agagcttgcg acgttatggt ttgccgttac
    78841 aagtcatgct tgatcccaaa aaccgtcaaa tcttaacgat cggattagct gggaaaacaa
    78901 atgaagatac acggatcaac gtgccaatcg atgacaactt caatactgta ttaaagagaa
    78961 ttcgttcagg agaaaacggg attttcgaac gattccgtga caatcttctt attgaaatcg
    79021 tgtcttactg gaatgatcaa cgattgaaaa acgatgaacc aactgcgcaa gctgttgcga
    79081 caccagttac agaagaaaca gtcagtgtgc cagaagaaaa aacggaaaaa ccaaaagcgg
    79141 acacaactga aaatacacgc tcaactgata cgaatgccgc tttaagtttt gctgattttt
    79201 caaaagccgt tgctgagtat cctaaatttt acacagaaca aaatgaacat gaagtagtta
    79261 ttaatgaaaa aaatgctgat gaacctcgta aattagcaac tatttctatg actactgaaa
    79321 atgagttcgt tatcgaaaaa gcactcgaac ggaaatacaa agtcaaattg actttgattc
    79381 ctttgatcga acaatttgca gcgacagcga ttactgatcg ataaaaattc tatttgtcat
    79441 aaaaggctgg gatttaaaat cccagccttt ttagtcatat aataatttct acagcaagta
    79501 aaaagaaatt ccttctaaca tcaggctcaa atatcagctt gacctgtcca acaaatcacc
    79561 tatgatccta caatgttagg cgacttctct tctacctgaa gatatcttgg agttgcctga
    79621 tttcttaaga tgcctaacct taactataaa aaattctaat aataaacata ttttctgata
    79681 gagaaaaaag cggttctata atattttgtg ttggtggaaa atcgaaagcg attttctact
    79741 aacacttttt tcttcgtttc aactcaaaaa gagactcact tttggtaaaa tttagtcgac
    79801 caaaacgtca ccctaccaaa ggagtctctc
//
LOCUS       DAMEEU010000004        76271 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.004, whole genome shotgun sequence.
ACCESSION   DAMEEU010000004 DAMEEU010000000
VERSION     DAMEEU010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 76271)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 76271)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..76271
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.004"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(71..1492)
                     /locus_tag="PB779_000288"
     CDS             complement(71..1492)
                     /locus_tag="PB779_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0737840.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="PB779_000289"
     CDS             complement(1735..3612)
                     /gene="tdc"
                     /locus_tag="PB779_000289"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDE0737841.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(3903..5159)
                     /locus_tag="PB779_000290"
     CDS             complement(3903..5159)
                     /locus_tag="PB779_000290"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HDE0737842.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(5271..5476)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5739..7040
                     /locus_tag="PB779_000291"
     CDS             5739..7040
                     /locus_tag="PB779_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HDE0737843.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(7109..7708)
                     /locus_tag="PB779_000292"
     CDS             complement(7109..7708)
                     /locus_tag="PB779_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0737844.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            7963..8844
                     /locus_tag="PB779_000293"
     CDS             7963..8844
                     /locus_tag="PB779_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0737845.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            8857..10467
                     /locus_tag="PB779_000294"
     CDS             8857..10467
                     /locus_tag="PB779_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HDE0737846.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(10544..11203)
                     /locus_tag="PB779_000295"
     CDS             complement(10544..11203)
                     /locus_tag="PB779_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDE0737847.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(11486..12151)
                     /locus_tag="PB779_000296"
     CDS             complement(11486..12151)
                     /locus_tag="PB779_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HDE0737848.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(12298..12903)
                     /gene="dhaL"
                     /locus_tag="PB779_000297"
     CDS             complement(12298..12903)
                     /gene="dhaL"
                     /locus_tag="PB779_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HDE0737849.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(12931..13941)
                     /gene="dhaK"
                     /locus_tag="PB779_000298"
     CDS             complement(12931..13941)
                     /gene="dhaK"
                     /locus_tag="PB779_000298"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HDE0737850.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(13916..14362)
                     /gene="dhaM"
                     /locus_tag="PB779_000299"
     CDS             complement(13916..14362)
                     /gene="dhaM"
                     /locus_tag="PB779_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HDE0737851.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            14465..14785
                     /locus_tag="PB779_000300"
     CDS             14465..14785
                     /locus_tag="PB779_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HDE0737852.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(14897..15766)
                     /locus_tag="PB779_000301"
     CDS             complement(14897..15766)
                     /locus_tag="PB779_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDE0737853.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(15862..17166)
                     /locus_tag="PB779_000302"
     CDS             complement(15862..17166)
                     /locus_tag="PB779_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDE0737854.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(17163..17672)
                     /locus_tag="PB779_000303"
     CDS             complement(17163..17672)
                     /locus_tag="PB779_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737855.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(17847..19982)
                     /locus_tag="PB779_000304"
     CDS             complement(17847..19982)
                     /locus_tag="PB779_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0737856.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(20065..21720)
                     /locus_tag="PB779_000305"
     CDS             complement(20065..21720)
                     /locus_tag="PB779_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDE0737857.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKGPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(21722..22036)
                     /locus_tag="PB779_000306"
     CDS             complement(21722..22036)
                     /locus_tag="PB779_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDE0737858.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            22206..22466
                     /locus_tag="PB779_000307"
     CDS             22206..22466
                     /locus_tag="PB779_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HDE0737859.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            22480..22794
                     /locus_tag="PB779_000308"
     CDS             22480..22794
                     /locus_tag="PB779_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HDE0737860.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(23524..24078)
                     /locus_tag="PB779_000309"
     CDS             complement(23524..24078)
                     /locus_tag="PB779_000309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HDE0737861.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(24204..26133)
                     /locus_tag="PB779_000310"
                     /pseudo
     CDS             complement(24204..26133)
                     /locus_tag="PB779_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(26439..27155)
                     /locus_tag="PB779_000311"
     CDS             complement(26439..27155)
                     /locus_tag="PB779_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDE0737862.1"
                     /translation="MNSDMTQIMGEFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMTGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(27156..28979)
                     /gene="glpO"
                     /locus_tag="PB779_000312"
     CDS             complement(27156..28979)
                     /gene="glpO"
                     /locus_tag="PB779_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HDE0737863.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(28993..30489)
                     /gene="glpK"
                     /locus_tag="PB779_000313"
     CDS             complement(28993..30489)
                     /gene="glpK"
                     /locus_tag="PB779_000313"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HDE0737864.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(30625..32085)
                     /locus_tag="PB779_000314"
     CDS             complement(30625..32085)
                     /locus_tag="PB779_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0737865.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(32075..33370)
                     /locus_tag="PB779_000315"
     CDS             complement(32075..33370)
                     /locus_tag="PB779_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDE0737866.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(33702..34379)
                     /locus_tag="PB779_000316"
     CDS             complement(33702..34379)
                     /locus_tag="PB779_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HDE0737867.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(34409..35500)
                     /locus_tag="PB779_000317"
     CDS             complement(34409..35500)
                     /locus_tag="PB779_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HDE0737868.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(35601..36035)
                     /locus_tag="PB779_000318"
     CDS             complement(35601..36035)
                     /locus_tag="PB779_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDE0737869.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(36619..38076)
                     /gene="ascB"
                     /locus_tag="PB779_000319"
     CDS             complement(36619..38076)
                     /gene="ascB"
                     /locus_tag="PB779_000319"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDE0737870.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(38073..39968)
                     /locus_tag="PB779_000320"
     CDS             complement(38073..39968)
                     /locus_tag="PB779_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0737871.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(40026..41801)
                     /locus_tag="PB779_000321"
     CDS             complement(40026..41801)
                     /locus_tag="PB779_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDE0737872.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARFPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(41851..43347)
                     /locus_tag="PB779_000322"
     CDS             complement(41851..43347)
                     /locus_tag="PB779_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0737873.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(43541..45163)
                     /locus_tag="PB779_000323"
     CDS             complement(43541..45163)
                     /locus_tag="PB779_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDE0737874.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(45491..46804)
                     /locus_tag="PB779_000324"
     CDS             complement(45491..46804)
                     /locus_tag="PB779_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDE0737875.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(47049..47273)
                     /locus_tag="PB779_000325"
     CDS             complement(47049..47273)
                     /locus_tag="PB779_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737876.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(47293..47715)
                     /locus_tag="PB779_000326"
     CDS             complement(47293..47715)
                     /locus_tag="PB779_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HDE0737877.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(47857..48567)
                     /locus_tag="PB779_000327"
     CDS             complement(47857..48567)
                     /locus_tag="PB779_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737878.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(48585..49082)
                     /locus_tag="PB779_000328"
     CDS             complement(48585..49082)
                     /locus_tag="PB779_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0737879.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(49119..49571)
                     /locus_tag="PB779_000329"
     CDS             complement(49119..49571)
                     /locus_tag="PB779_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDE0737880.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(49706..50311)
                     /locus_tag="PB779_000330"
     CDS             complement(49706..50311)
                     /locus_tag="PB779_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDE0737881.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(50761..51381)
                     /locus_tag="PB779_000331"
     CDS             complement(50761..51381)
                     /locus_tag="PB779_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HDE0737882.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(51383..52252)
                     /locus_tag="PB779_000332"
     CDS             complement(51383..52252)
                     /locus_tag="PB779_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HDE0737883.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(52275..52682)
                     /locus_tag="PB779_000333"
     CDS             complement(52275..52682)
                     /locus_tag="PB779_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HDE0737884.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(52701..53990)
                     /locus_tag="PB779_000334"
     CDS             complement(52701..53990)
                     /locus_tag="PB779_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0737885.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGGFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFNNATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(54017..54319)
                     /locus_tag="PB779_000335"
     CDS             complement(54017..54319)
                     /locus_tag="PB779_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0737886.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(54344..56437)
                     /locus_tag="PB779_000336"
     CDS             complement(54344..56437)
                     /locus_tag="PB779_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDE0737887.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(56926..57690)
                     /locus_tag="PB779_000337"
     CDS             complement(56926..57690)
                     /locus_tag="PB779_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HDE0737888.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(57801..58670)
                     /gene="mdcB"
                     /locus_tag="PB779_000338"
     CDS             complement(57801..58670)
                     /gene="mdcB"
                     /locus_tag="PB779_000338"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HDE0737889.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(58695..59771)
                     /locus_tag="PB779_000339"
     CDS             complement(58695..59771)
                     /locus_tag="PB779_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HDE0737890.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(59795..60388)
                     /locus_tag="PB779_000340"
     CDS             complement(59795..60388)
                     /locus_tag="PB779_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HDE0737891.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(60392..62068)
                     /gene="mdcD"
                     /locus_tag="PB779_000341"
     CDS             complement(60392..62068)
                     /gene="mdcD"
                     /locus_tag="PB779_000341"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HDE0737892.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(62058..62357)
                     /locus_tag="PB779_000342"
     CDS             complement(62058..62357)
                     /locus_tag="PB779_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HDE0737893.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(62459..64105)
                     /gene="mdcA"
                     /locus_tag="PB779_000343"
     CDS             complement(62459..64105)
                     /gene="mdcA"
                     /locus_tag="PB779_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HDE0737894.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(64112..65023)
                     /locus_tag="PB779_000344"
     CDS             complement(64112..65023)
                     /locus_tag="PB779_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDE0737895.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            65143..66000
                     /locus_tag="PB779_000345"
     CDS             65143..66000
                     /locus_tag="PB779_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0737896.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(66187..66549)
                     /locus_tag="PB779_000346"
     CDS             complement(66187..66549)
                     /locus_tag="PB779_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HDE0737897.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            66895..68334
                     /locus_tag="PB779_000347"
     CDS             66895..68334
                     /locus_tag="PB779_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0737898.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(68341..70893)
                     /locus_tag="PB779_000348"
     CDS             complement(68341..70893)
                     /locus_tag="PB779_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HDE0737899.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(71007..72338)
                     /locus_tag="PB779_000349"
     CDS             complement(71007..72338)
                     /locus_tag="PB779_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0737900.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(72304..73782)
                     /locus_tag="PB779_000350"
     CDS             complement(72304..73782)
                     /locus_tag="PB779_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0737901.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(74087..75922)
                     /gene="tdc"
                     /locus_tag="PB779_000351"
     CDS             complement(74087..75922)
                     /gene="tdc"
                     /locus_tag="PB779_000351"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HDE0737902.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
BASE COUNT        21819 a        16178 c        13059 g        25215 t
ORIGIN      
        1 aaaaaactat tcacttggca ggacctccta ctaaatcagc gacaaaacgt cggctgaaag
       61 acttattttt ttatttttct tctaaacttt tttctacctc aatcccccaa gaatctttct
      121 tgaagtgatt gatgatcaat ggaataacga acatgaccac tgtgatagct gctactaata
      181 atgcatcact caatgtcgct gtacctaatg tagcaaatac gacaacgatg atagagaaga
      241 tcagcatgca gctgactacc caagctaatc cgtttccgtt tttaccaatt cggtaaggac
      301 gttcgaattc tggatgtttc ttacgcattt taagcaatga aacagcaatc aaaatgtaca
      361 cgatacaata aataacagtt gtagcatttg taagtgtcaa gaatacagca cttacgtcat
      421 ccattacacc ataaagcaaa gcaaataatg aaataacgat tgattgtgtt agaacgacat
      481 ttctagatac gccgtatttg ttttctttat ggaatccgaa ttttggtgga aggaatcctt
      541 cacgagctac ttggatgatt gtttttgatg gtccagtaac ccaagctgat aattgtaaaa
      601 gcacaccaat aaataccatg aagctgaaga tatttccgat cacttctggt aagcctagga
      661 tttgacagtc aatcaagata ggctgcgtga tatttgctaa ttccattttt ccatctggta
      721 cgacatttgc tacaagcatc gcattgatga cattcaataa aactaatccg atcaaagcga
      781 taaatacgcc ttttgtataa ttttttgttg cgtctttcaa acgaggcatg taaacagaac
      841 tcatttcgat cccaacaaaa ataaatgtga taccagctaa gtatttcaat gaatcaatat
      901 gttccaagtc agggaaagct tttgaccatg aaaagtcacc tagatagccg tttgagacta
      961 gtccgacttt gaaggctgcc aaaacaccta aaacgaacat gatgactact gggatatata
     1021 cccctagcca tacaccgatg ttcccgccga cttttgccat atcgaatttc aagttcaaga
     1081 tcgtgatgat ccagtagata actaaaatac aacctaaaac gaaccagtga ttattgccaa
     1141 gttctacatt accaaatgtg tttcctaaca atggtcctaa agtagaagcg accattacca
     1201 tacctgggaa catttgcacc cataatagcc atgcaacgac aaatccccat ttgctgccca
     1261 gtgctgtttt tacccataac tgaggaccgc cttcttgagg aagcatcgtg gaaagctcac
     1321 cggaaaccat tgatatcgga ccggcaaaaa acaaaactgc aaaaattgaa taaaaaatca
     1381 atgtccaacc gactgcggct aacgtaggaa tactccgaac cgttgcacac agtgccattg
     1441 tcagaccgat aaaggtccca agacccattt tacttacttc agatttactc accgttgaca
     1501 ctctccttga ttttttggat aaaataacgg tgtctttgaa gtagtttcag caataaacga
     1561 aacaattcag cgaatatttg aggggattct ttgagtttat tgcttgaagg gtttcttcaa
     1621 agacaacctc aaaacaaagg gatcgaagag cttaggtctc cccttgctct tcagatccaa
     1681 acatgcgtca gaaacagtta gtattcaagc tgttttctaa catgattacc ttgcttattt
     1741 tgcttcgctt gccaataatt ggtctgcgta gattttttcc aatttttctt gaagagctgc
     1801 tttgattttt tcagcatatt cttcaaagtg ttcttctttg ttcatgtatg gtgtcattac
     1861 gctggcacgc aatacagtta cttttccggc acggttccat tcttcatctg agaatcctag
     1921 ttggttcaca aattgtaatg ggctgttgcc atagtctggg atagcaaagt cagtatgtga
     1981 agttaagaac tcattaccgt aaatgcttcc tttcacgtat gaagaataat catatacgtc
     2041 atggttcaat ttattcattg caactaagtc atcgttgcct ttttctttga atacatagtc
     2101 taccatattg aaatctggat aagttaatgg atgaacttcg atttctttgt ctcctacttt
     2161 aaatgacaag tcattcaaga agttgtagaa acgatgtgca ccttcgattg atgcacccat
     2221 taatttacca tatcctgtga cattcaaagg taagacatgg tgtgctgccc aaacgctggc
     2281 tgctgttgcc cctgcttttg aaccttccaa gatataagcc ccaagtaatg ctgggatatc
     2341 tgcgcctttt tcaaatacat atgtcgcaaa gtaagagata acgtctctca tgcggatatc
     2401 tttgatgacg ataccaccgg cagaatatgg aacatagccc attttatgtg ggtcaatcgt
     2461 tacagattct gcttcttcga ttgctttata tgcactgtgt acttcttcta agatataatc
     2521 tttgttttct gtaaagacat tgtatttgta atgaacatct tttaaatctt caaatggaat
     2581 gaagttgttg tcttcgtcta agaaaatcgc acggccgtat ccgccataag cagcatctac
     2641 gtgtaagtag aagtaaatac cgtctttttc taatacgcga cgcaatgcaa cgattttatc
     2701 gataccgtcg attgctcctt cttctgttga tcctacaaca ccgactacac ctaggattgg
     2761 tgttttttca gctgctagac cacgaacgat tttttcaagt tcgttgatgt ccatgcgata
     2821 gttgtggtca actggcactg gaatcacttg gtctaaaccg ataccgatga tgtcggcagc
     2881 ttttagccat gaatagtgtt tagtttgtgg aaccaaccat tttcctaatt tttctaaatg
     2941 ttttccgcta cgtgctgagt gagctttgat ttcgtcgatt ttttctggga cgctgtctaa
     3001 cagattcatg atttcttctg ttgacaagtt cattaattcc caatcgcttt ttccagcaac
     3061 tagttcaggt gtcacttctt tcattgcaag cggcaatgat ttgatgttgc gggcatacca
     3121 aagtccttct aagtttgcta aagaaccatc agcaacgatg tggccccagc catctttata
     3181 gctcattaat tttgcaaatt ccattcctac ttcttcttcc atttggcttg ttgcaggaga
     3241 agattcatag gcaacgttat taccattcca tagcatagca aaattgtacg ctagtaaaga
     3301 tggcatcaat gtttcagagt tcatatgacc ccagtaacgt ccggcattat gccaaggaac
     3361 ggaatgggta cgcatccgcg ctgaaatttc tgatagaaca tcctttgttt tattcacagt
     3421 gtgttcaaaa ctagcactgc ttttttcttc tggcgtaata ataggcatgt cttgaggcat
     3481 gtagttttga cgccagccta aatgttcatc caccaattca ttcaacaaag ctttatagat
     3541 ttggccgttc tcagctttgt ccccaatgaa tagggcattt aggtttagat ctttcgacaa
     3601 tgattcactc atagtgaaac cctcctaaaa aaatatttaa attttgtcga gccctacatt
     3661 acacctgttc ttctattctg taaactaagt tttggcctga tttttaatca tattttaata
     3721 tgtatcaatt atccgaattg ttcacacttt tgaaataatt aaaaaaaacg agggaattta
     3781 caaatgtaaa ctccctcgca aagattgtat taacgacaac cagcgttcta ttttaggatg
     3841 ggtttcaaaa ttggaatgtt gtaatagtat ttcccttttt caaggtaaaa acttactaaa
     3901 ttctaatcaa ttactttggc caaaaagtaa tttttcttac cttttcgaat aaccacaaac
     3961 ttaccatcga attcatcgga tggatttatg acaaaattta aatcggtaac gcggtcaccg
     4021 ttaatactta tagctccgtt tgaaacatct tcacgtgctt gacgtttaga tggttcaatt
     4081 tttgtggaaa caagcagttc cacgatattt tcaggtgtgc ttgaaatttc aacgttcggc
     4141 attttaccga atccttgcgc gatttcttcc gcatttagtt ctttaatatt tccagagaac
     4201 aatgcttgcg ttattttttg cgcttctttc aagtcttctt cactatgcac aaatcttgta
     4261 acttcttctg ccaaacggcg ttgtgcttca cgtttctcag gttctgtctc tacttttttc
     4321 gctaagtctt cgatttcttc ttgagacaag aaagtaaaga atttcaagta tttcactaca
     4381 tcgcgatcat cttgattcaa ccagaattgg tagaactcaa atggtgaagt tttcttcgga
     4441 tcaagccaaa cggcaccgcc tgcagttttt ccgaatttcg ttccgtcagc cttcagcatc
     4501 aatgggatcg ttaaaccgaa cgcttctgct tctggtcctt ctaattttcg gattaggtct
     4561 aatccagctg tgatatttcc ccattggtct gctccaccga tttgcaattg cacatcgtat
     4621 gttttatgca gatgcaaaaa gtcgatagat tgcaggattt ggtaagtaaa ctctgtaaat
     4681 gagattccta cttccaaacg gctggcaacg atatcttttg ctaacatcgt gttgatgttg
     4741 aagtttttac cgtagtctct caaaaattca agtaaagaga tttttgacaa ccagtcgtag
     4801 ttgttcacaa atgtgatatt tgcatcttta ccaaacaatt ttctcatttg attggaaagt
     4861 gcgtccacgt tatgttgcac ttgttccatc gtttgcaaca cacgttctgt tttgcggccg
     4921 cttgggtcgc cgatcgttcc tgttccgccg ccaatcagaa tatatggatg atggcctgcc
     4981 aattggaatc ttttcatcat cataaatgga atcaaatgtc cgatatgcat cgaatcacca
     5041 gttggatcaa cgccgcaata aagtgaaatg ctcttttctt caacgagctc gcgaagtctt
     5101 tcttcgtttg tttgctgatt aatggcgtcg cgccaagtta attcatcaat aatattcatt
     5161 ttactgacct ccgtgtagtt tttttatgaa agcaggaacc tgctagcatg tgtaattaat
     5221 tatttcttca ggataggata ggaaataaaa aaagtccctt ggcatataag ccaagggacg
     5281 aaatctcgcg gtaccaccca atttgtatgt ctagatatcc aacatacctc tcgaacattt
     5341 aacgctgtcg cgtggcaatc actgccaaag actcctgaaa tgtaattcgc tttaaagcat
     5401 gtactggttt gcagcgacca ccagctttct gaaacattgg ctttaacaac tacttcgttt
     5461 cgatcttcgt cttgttatta ttaatatgtg tctatcatag agcgcaactt tttctttgtc
     5521 aacagaaaaa ggatattttt tttaaattcc tcattttttc ttttttgaat ccgctctaat
     5581 tccgaacatt ttattttcaa ttattgttaa aagaaataac tttttctgta ttttttctgc
     5641 aatttatcga gaagtcactt tactttgcct cttattcttt cttcgttaca ataaggaatg
     5701 ggacaagtaa aaaaatgaaa aagcaaggga cgaggtatat ggaaaaaaag caaaaaatta
     5761 ttttaggagc cacttctgct ttaactatcg ttattttaat tctaagtttg ttttttgtca
     5821 tccgatcatc tacaaaaaaa gaaccaatca ttcctgaaaa aaaaataaca gaaaaagcaa
     5881 aagaaccgac agatgataag caacaactag ttactcaagc aaaaaatctg gctcaaagct
     5941 acgattatga ccaagcgatt gcgttattgg aaaaagatag taagaacgga tctactgaaa
     6001 cacaacagct tcttcaaaca ctaaaaaagg agaaagaaca actgatcgac tggtctgatc
     6061 ctactcagat ctctcatgtc tttttccaca gcttgatcgt ggacccgcaa aaagccttcc
     6121 actctcaaca ggcacaagga tacaaagatt atatggtgac tgttgaagaa ttcaaccgtt
     6181 cgatcgaaca actttatcaa aatgattttg ttttagttaa tttgaatgat ttgatccaaa
     6241 aagacgaaca aggaaatctt tcctttaacg ggcttgcgct acctgaagga aaaaaaccat
     6301 tggttctttc acaagatgat gtcagctatt atgaatatat ggataattcc ggttttccta
     6361 gccgattggt cgtatcaaat aacaatgaaa tcaaaaatgt ctataaagag aaagataaag
     6421 aagaaatcgg tgactttgac atggttcctc tgatcgatgc ctttgtcaag aaacatcctg
     6481 atttttctta tcgaggcgca aaaggtacct tggccctgac aggttacaac ggagttttag
     6541 gttatcgaac atcaaaatct caatatggag acaatgaaaa aacaaaaaaa gagattaaag
     6601 aagctaaaaa agtggcggaa cagttgaaga aagacggctg gagctttgct tcccatacat
     6661 ggggtcactt gaatatgact caagcttcac tagaagatgt aaaaaaagac aatgaattgt
     6721 ggcagcaaga agttgcacct atcctaggaa aaacaaatat tctgatttat ccatttggtg
     6781 cagacatcag cgactggcag ccttattcag cagaaaatca aaaatttgct tacttgaaga
     6841 gtcaaggttt cgatattttc tgtaatgtcg atgcttctac accagcttgg ggacaattag
     6901 gtacggattt ctatcgaaat gctcggatca atatcgatgg cattcgtttt caatctgatt
     6961 tagacggaaa aaatcctatt cttgatccat tcatcaatgt ccatgatgtc tatgacaaag
     7021 aagcacgcga atctgcttga ttttacgtca tttatgaacc aaaaaagccg aactgacatt
     7081 ttatcgtcag tttcggcttt tttatgcttt atttcttctt cggtgcgatt cccttgatca
     7141 ggacttctgt ccattctgct gtatatggaa gcagttttgc gtatatctcc ggcttagaaa
     7201 ttccttctac cattgcttga aaatagagga tcaagaactc atccgaatat ttcaaatcca
     7261 cttttccttc tttccgccct cgatggaaaa gatcaagcat gatactgaaa ctttcttgcg
     7321 tatacgcatc catcgcgtca gaaaattctt ttttttcttt ttttgtatag tatgtcatca
     7381 aatcgatata aaattgtttg ttcactcgat tgagataacg gattttgttt tcactcatgg
     7441 caatcagtgt ttcttcaaat ggaagatttt ccgcaatcaa cgctttcgct tcttgcccta
     7501 aatcattcat aaatgcaaaa aatacttcat aaatcagccc ttccttgctg ccaaaatatt
     7561 taaaaatcgt cgctttactt acctgagcgt tctcagctac cttatccatt gtcactccag
     7621 cggttcctat gtctgtgttc atcaagtcaa aagctgcttg taaaatctct ttctttttct
     7681 cttgtgctct cttttcaaaa ccgttcattt gtagagcctc ccgtaatttt aaacttttat
     7741 aatatatata gttcaaattt attctgaggt ttattataac tatctattga gaaagtatca
     7801 agctagcaat tccttgttta tgaattcatt gacagaaatt tataaaaaga atattatgta
     7861 ctaaaataat aaaaaaaagt tttataaaaa ggtataaaac ctttttatta aactatttaa
     7921 tcttgtttag tatatatttt tagaaaaagg agtggggttt ttatggcaga aatcgtcaaa
     7981 gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt taaaagatgt ctctttcacc
     8041 gtacattcag gtgaagtcgt tggatttatc ggaccaaatg gttctggaaa atccacgacg
     8101 attcggacac ttttagggat tataaaaaaa gacggcggaa cggcaacgat ttttgggcaa
     8161 gatgtatggg aagatagttt atctatccat gaacgtcttt cttatgttcc aggcgatatc
     8221 tctttgtggg gaaatttgac tggaggagcg atcatcgatc tcttcatgaa gcttcatgga
     8281 aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt tctctcttga tcctaagaaa
     8341 aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg gcttgattgc tgctttggct
     8401 gttgattcgg atctctattt atttgatgag cctacttctg gtttagatcc tttgatggaa
     8461 acgattttcc aagaagaagt tgaaaaattg aaagaacagg gcaaatccat cctactttct
     8521 tctcatattc tcagtgaagt cgagcgacta gcggataaag tcgtgatcat acgcgaagga
     8581 acactcgatg aagaaggaac actcgatgaa ttgcgtcatt tgactcgttc gaccatcact
     8641 atagaaacag aagcagagaa tagtcactta gcacaattga acggtgtcca tgactttgtg
     8701 caaaaaggtc acctcgctca atttgctgct gataacgaag ctttcgatgt gattttagct
     8761 gaagcgtcca aattaggtgt gaaaaaattt gaatctattc caccgactct tgaggattta
     8821 ttcatgagac attatgaagg atgaggagga agcgaaatga ctgataaatt ttcacgctgg
     8881 tccacccttt tttctcaaaa ccttagccgt gactggaaaa agatcctgat atggctagtc
     8941 ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg aagaattgac ttccggacaa
     9001 ggattagctg gattatacga aaccttgcaa aacccggcaa tgattgcaat ggtcggacca
     9061 actccagctt cgaatgctgc tgagtatact ttaggagcga tgtatgcaaa tgaaatgttg
     9121 cttttttgca gtttgtttgc tgctgtgatc tctgttttac acgtggtgag ccaaacgaga
     9181 aaaaaagaag aacttggtct gattgaactt attcgttcct ttcgagtcgg acgtcaagca
     9241 aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt tgcttttagc aatatcgatc
     9301 agctgtacga tgattttttt ccaagcggat tcgatcactg cagaaggtgc ttggcttttt
     9361 gggctatctg taggtagtat ggggattttg gggagtgccg ttgcactgtt tgctgcacaa
     9421 ctgatgccaa gttcagccag ttcgaatggt ctgtctttag cgtttttagg tggactttac
     9481 cttctacgag caataacaga tgtagctgat tcctcccttt cgatgtggaa tcctttaggc
     9541 tggtcttatt tgacctatcc atttacaact aacaactgga ttcctttgct ttatttgttt
     9601 ttgttcagtc taatcttgat aatcagttca tttgttttag aggaacatcg agatttgaac
     9661 accggctata tccccgaacg tgaaggaaaa ccgtatgcta aacgttctct tttatccttg
     9721 cgtggtttat tattctatct aaataaaggg atgacaatca gttggcttat cacttttggt
     9781 ttgatggggg cggcatacgg ctctatctac gggaatatgc aacagttttt agaaagtaac
     9841 gacttaatga aacagatgtt tatccaatct ggcgtctcaa ttgaaaaaaa ctttacaagc
     9901 acgatcatgg tagtcttgat ttgtctagct gctattttac caattgctag catcaatcgt
     9961 ttatttacag aagaaaccca cggacgtatg aatcagctgt tcgcaacaaa aatttctagg
    10021 aaccaacttt attggaccaa tatgttacta gctattctat ttgctatatt ggcaatcctg
    10081 attagttctg gtgcactagg gctttctgct ttggcttcga tgaaggatgc gaaagacatg
    10141 gatctattga tgtttcttaa agccgggttc aatttcctgc ctgccgtttt agtgtttatc
    10201 ggaattagtg gctttctatt cggatggctt cctcgaatcg gtaaacttgc ttatatctac
    10261 ttagcttact cctttgcact caattacttt ggcggaattt tggatttacc agaatggttt
    10321 tccaaaacag ctgtccctag ctgggttcca cggatgccaa acgattcttt tgatctttcc
    10381 gtgttcctta cgttatcatg tatcagcctt gcactgttcg tccttggttc tattggttat
    10441 aggcgaagag acttactaga aggataataa aaaagcatgt acaatttcat gctagcctcc
    10501 aaatctgggt caaaaatcca acatttggag gtcatttttt tatttacaag tcttctaact
    10561 gctctttatc aatgatccag acttctcgat tctttctttt tacataacca ttctcctcta
    10621 ataatttaaa ttttctagat aaagtttcgg gggtcgtacc gataaatgca gcaagttctt
    10681 tcattttcat tggcaggaaa aagtgatcct tccctgtcgc tttagctaag tcaagcagat
    10741 agacagcgac tcgttcttct actttttcca tcatcaaaaa agttgtctgc tgctgtactt
    10801 ttgttaattt ctcaacgttg attgctaaaa gtttcagact aagggcggga taatgcagta
    10861 agagttccga gaaatctttt tgtctcaata tgcaaatttc cgttttttct agtgcttcgc
    10921 caaataaaga ctcatttgga acgcctagca actggctctc tccctcatat ccgcccggct
    10981 ctattactcg taaaagctgt tcctttccgc tagcagataa ttgatacact ttcatactgc
    11041 cggaggccac gatcactaat tgaggttctc cattcggcgc aagaatctgt tctccttttt
    11101 ccacatagtg atgtttgaca agtgcgtgta ctttttcttg atcttgctgt actaagtgat
    11161 tgaacaaagg aacaaatgaa acacataaat gatcatgact cataatctct cctccttcta
    11221 aacagctatt tctaataaag aaacataact tcccttattc caactgataa ttttctttta
    11281 tcatagcata aacgtcaagc gaaccagata ccagcaaata gagtggattt ctttttgtcc
    11341 cttgctttat tttccttctt ttgagacctt aagtaattga ttcctatcaa ttttttaaat
    11401 atttactttt tgaataatca aaaacaaacc ttcactcgca agccgagagt aaggtttgtt
    11461 tttcgcattg cttatttcgt gttgtctatt gaaatttttc cgcacctagc ttttgatata
    11521 gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc aacgtgttcg atttcttgcg
    11581 gatagaagaa tagtttaccc atttgaaagg ttcggtctct catcgctttt ttcaactctt
    11641 cttgtttctt tgtatcggac aaatagtcag acaaagctaa gtggtcgtca agttcatgtt
    11701 ctggttgcgg ccatatgtaa taatccttga tatcgactgt tttgctccac tctttcagta
    11761 tcgcaagcaa ctggttatac gctgcaatgc taccatatcg ttcttcgctt ttataatgtt
    11821 ggtacatcaa atagatttgg tattgttttt gattcaacaa aactgctaga caggcattct
    11881 cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg actgcgtaaa ttccagccat
    11941 tcgtccagct ttcgatttta ggtttgctca tgccgtacat atcaggcaaa agtgcagctg
    12001 tctggagctg aatctctttc catttttgcc agtgttcttt atattctttc ttgatttgtt
    12061 caatcttatc tgttggatgg ctctctttga gctgtttgaa tgcgtagatt ggtcgatcaa
    12121 acaactgata atctgatttt ccaagttcca ttgtttcgcc tctttccgtt atcttttgta
    12181 ttctacctga attttgcgat atggacaaat agaggttgtg aaaaagctgt tctgcatcaa
    12241 gtcataagaa cagccaaaca aaaaactgcg atgagcatca ccgcagtttt attgaactta
    12301 aggttgattg atcacatcta aaagcgttga aaataaaatg gcactagaag cagctcctgg
    12361 gtcgatatgt ccgattgcac gctctcctag ataggaagct cgtccttttt tagctaccaa
    12421 gactttggtg tgttcttttg cctggtcaat gatttctttt gttaaattcc ctgccttcaa
    12481 tgcctctgtg actggcagcc aaacatctaa catcgtttta tcgtcagctt ctgcctttcc
    12541 tcggctttga atacccgctg ttccctgctc gatcacttcg cctaattttt cttgagaatc
    12601 aatagaatcg acctcttttg tcgctttcat catgttcatg aatgcagatc cgtataacgg
    12661 accagaagcc ccaccgactt tcgatatcat cgccatagag aatactttga atgtatcgct
    12721 gattgtttca ggatgatcgg cttgaaaagc ttcttcataa gctgaaaccc ctcttcccat
    12781 gttatttcca tggtctccat cgccaatcgg ggtatctaga tcactgagat attgtttgtt
    12841 ctgattgatt gcctctgcaa attgcgtgag ccattcttgg atttcttgaa cggttagttt
    12901 catattatca cccttttatc ttgagatttt ttaccatgaa atcgtctgta cattgctttc
    12961 taaagaatct ttccattgtg tctccgtcaa gtcgatcagt gttagagaaa gaccttgcat
    13021 atctagtgag gtcataaaat taccgacttt tcggaaaact acattgacgc ctctttcttc
    13081 caacagagct aaaacatcat tcatgaacac gaactgttcc atcaaaggcg tcccgcccat
    13141 tccgttgact agtacacctg cttcttttgg taaattcgag taatcatcta aaatcttagt
    13201 aacaagttcc tttgccagta ctttagaagg ctgcatcttt tctcgacgat agcctggctc
    13261 accgtggata ccaacaccat actcgatctc atcttctcct agttcgaatc ctggtttccc
    13321 tacttctggt acagttgctg ctcgaagcgc tagaccgatc gtcttagttg cctgtacgac
    13381 cttttctccc agttctttca actcagctag ggaagcaccg tttcttgctg catcgcccac
    13441 gattttgtgt acaaggacag tacctgcaac tccgcgtttt ccagcagtat acgtactatt
    13501 ttcaacggcg atatcatcat ctacgatcac actttctact tcaatatcgt ccatagcagc
    13561 taattccttt gccatatcga agttcaatgc atcccctgta taattcttaa cgatcagcaa
    13621 aactcctttt ccactatcgg cttccttaat agccgtctga atctgatctg gagttggaga
    13681 agtaaacaca tcaccaagca ccgctgcact taacatccct tcccctacaa acccggcatg
    13741 ggatggttca tgtccgcttc ctccaccaga aaccaaacca acttgttccg ctttctgatt
    13801 cttggctaca acacgggaag attctacacg atgaacaagt tctggatagc tttttactaa
    13861 tccttccagc atttcttcga caatattgct tggatcattc atgatttttt tcaatttatt
    13921 cccatccttt ctttccggca ttttgtgctt ctgttaagat ttgctgagta tcatctgtta
    13981 taccggcagt gatggctgct gcaaaagctc cttccactaa aggcgcatcc accagatgat
    14041 aacgttgctg ctgctcttct tccaacatgt cttttgccag ttccgagttc aataccgcgc
    14101 taccgatatc cgcaaaaaca aaataactag ctgcatcgct tgattcattg actgcttcta
    14161 cgattttcat cgggtctgat ccgatctcgc catttattcc gccgagagaa aaaatttgca
    14221 cctcttcgga tttttgcatc tgctcaatca tttctttaat accatctgtt actttttgac
    14281 tatgagaaat aagcaaaata ctttttttca caagaatctt cctttctttt acatagttgc
    14341 taacgattgg tttcgctttc attaatgaac aattcaagta tataataaat ttctaatttt
    14401 gggaaaatat gtgtagtgct tcttgaagtt tgttatactt taattaaaag agaggagtga
    14461 tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa gccgtagtag cttataaagg
    14521 gatcgttttt ggtgaggtca ttactgggat ccatgcattt aaagacttgg aggcggggtt
    14581 gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac gaactaatgg gtgcaagaga
    14641 agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta ggagctgatg cgatcattgg
    14701 cgtaaaaatg gactatgaag tattaggcag cgacaatggc atgctgatgg tcacatgtag
    14761 tggaacagct gtctccacga gataagtagg ggacatctgt tttaataact aaagagagat
    14821 gggacatgta gtggcactca agaattagat ttttcagtct aacttcgagg tactctacct
    14881 tcccatcctc tcttttttat ttctttttgc ggatgattcc gtaagctgct gcgactaaca
    14941 cacccgcccc tgctaaggaa taactgacag aagctgtttt ttcatttgtt tttggcaaag
    15001 tctgacttgt tgatttggat ggctctgtcg tttgctgaac tgtttctgtc gtgcttccag
    15061 aggtcactga tttttctcct gccgaatgca aaatatcttt tattcgttgg aaactagctg
    15121 ctaagtcagc tttttttgct tcaaaatcat tagcaactgt ttgtgcttcg ctgatctttc
    15181 cgtggattgc ttgactggcc gctgtgatat ccgcttgagt ttgacttagc tttccagaag
    15241 ctgtttgagc aacctgattt aattgctgat tgaattcttt tgcttgttgg atcttcccgt
    15301 caagatctgt ttggacagct tccgcttttg ctttcgcttc ggcaagcttt ttctcaagtt
    15361 gtgcacggtc atttcccact ttatttttaa gatcagctaa atcttgatcg attgctgctt
    15421 ggtcttcttt caatttgttt tttgcagctt ctaatgcttc ttcgagttct tttcttttat
    15481 tttccaagtc ttgcaaatga tcgatttggt cagaagaggt agaactattt attgatgtat
    15541 cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg tacattggaa gtcatttctg
    15601 tttccgaggc accgttttca gcaccagaag agcttatggt tgttgaaggt tctgtttgag
    15661 caggttcaga agtttccgca aaagctgtct gtcccaataa gaaaatactg gaaacagcaa
    15721 ttggccagat taacggcttc attctttttt tcatcacttt tcccatcctt actacttttt
    15781 aactaatttc ttattataag caaaaatgtt tggaagaacc ataaacacaa caggctgttt
    15841 gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc gggcttttcc atgtcccgct
    15901 tccataacct aaaatcgttt tgactgctgg aatgaaagtc gtcacgatcg ttatcgcgtt
    15961 cactatccag aacaaaagca tatatagtgg tgcgaaaaga aggtatttca attttcttcg
    16021 tcgatcatct acaatcagcg aagctagcaa ctggaaaaat cctgcgacca tttcaaagca
    16081 gatgaacaca aaactgaatg taaaagtaat ataaatctgt tcgtagtttc cttgatatac
    16141 ataatgcccg attaatccag caaaaagaac tacggaaata caaaagaata ttgaccagac
    16201 aatactcaat gtttgatcaa tgaagatgat cgttcttcca atatgtttaa aaggatggag
    16261 catcactttt ttgaaattcg tcagccagac ttctgttcca ccttttgccc aacgttttct
    16321 gtgtcgatat agcatcttca acgtcacagg tacttccatg aaaaagataa tctcaggagc
    16381 aaaaacagat aaccagtcat ttaactgatg atcccaagca atactgatgt cttctgtcgc
    16441 tcgatcttgt ctgaatccgc ccacatcgat caaggcttct tttcgataca tcgtatttgc
    16501 tccactgtac gcataaagac caccgaaaac agctgactgt gttcgtttaa tgatgcccac
    16561 gatacttgag aattcaaccg tttgagattt tgcaatcaat ttggtacgat tttggacatc
    16621 catatttgca gtgaccgcag caatatgtct tgcaccaggg cgaatgaaat aattcacata
    16681 cctaatcagt gcatctggct ccggtaccgt gtctgcatca ttgcttaaaa tcaatttccc
    16741 ttttgcaaag gcaagtccga tattaaacgc gtgggctttt cctttatttt tttcgatccg
    16801 aaccacacga agattagcgt attttttcat cagtctagct aatatttctg gtgtttggtc
    16861 cgttgaacca tcgtctgtca ctaatacctc atagttgtga taattcaatt tcgtcatcaa
    16921 atactcgatt gtatattcga tcacaatttc ttcattatgg gctggcacca tgatcgtgat
    16981 gaacggttcg acactcaagg gaacatctac ccattctttt tgcttatgtt tgtataaaaa
    17041 cacataacac cagacaccaa taaaccatac aaatccgcct aaaatcggat aagaaacgag
    17101 aaaaaaatac ataatagaca aacaagtatc taagaataaa ttacctgtat gggtgattga
    17161 gatcatttca gttccacccc attttcttta tacaaatctg caatgaatgt cgtatctaga
    17221 tttttctctt cggagacaga ataaaaacgg accgtttctc tctcttcttt tgttccaaaa
    17281 cgttccgtat acacttcttc aagtaattct tgtctttttt tcaatttttc atcttcatat
    17341 tcaaaagatt tatttacttt tttgtataga tttcgattgt tccacctagt caatacaaat
    17401 gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc cgattaagaa atacagcatt
    17461 ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg ctctttctgg tctcgttaat
    17521 gggaaaaaga cccatataaa aggaagaaca acgatcatcc atcctaaaag agccactaac
    17581 gtttgccaaa tctttaacca gtaattacct tttgaaaaat acttatcttt caccaaaatt
    17641 gatgcaactt cttctcttgt tacttttttc atatcctcac ctcacgtttt tttgttacga
    17701 cgtaggagtt taccatacat ttcatttctt ttcacataaa gtgttcctaa atttttccta
    17761 agaaaaagaa caaaacattt ctcatcagca aatgaaaaat attttgttct ttttatcagt
    17821 tgttcttttt attttttatc tcttaattat gttgctcttt ccaatacgac aatgcttttc
    17881 attcctctag atatcgccgt gtacatttgt ctgcgtcttc tttgctcatc tccatcgttt
    17941 tcaaatggat ataagattac atgatcaaat tccagtcctt ttgctagact caaaggaatg
    18001 atttggcagt tttctaatcc atatgaattt tttttaatcg attcttgtag cgtttgggtt
    18061 tcctcttctg tttgggtgat aactgccgct ttttctcctt ttagagaaac caaaatctca
    18121 gctagtattt tcaacaattc ttcagaggat cgaaaagagc ggtattcggg ttcttttcct
    18181 tgcggtcgga tcgatacgat gtcgatcttc tcttgatcca cagcataggt tttgaaaagc
    18241 tctgtgattg ctccgctaga acggtaacta tttctaagat cataccgatg gatcggcaga
    18301 tggtagtcgt cgaaacaacg cataatatca gcaaaagtag tggaagaatt aaagattgcc
    18361 tgattctcgt cacctactaa agtaaagtga gtttttggaa ataattcgat caatagacct
    18421 aattgtgcca gggtataatc ttgtacttca tcaatcaata gatagcgaaa tgctggtaca
    18481 tttacctttt caacaagtaa atgacgaata gctaatataa tgactgcttc atcaacagta
    18541 cgtgtgggtt gccaagcata agctgagcca tatcgttttt cataaattct ttcaaacaac
    18601 tgatgctcat ccacccatgc catttcttcg atttgtctgg ttatttttcg atattttttt
    18661 tgtaaaagtt tccttgcata agctacaata ctttgttccg aatcatcaga aatcaattta
    18721 ccgaataatt ccaactgcct atcttctgtc aacgagagta cctgattctg cacagcagga
    18781 ctttttgctt gtttcaaaag atgattcttc cattcgctca tcagtgcctt tttcgttgct
    18841 tgaagcctat cgatcaattt aggatgagca ggaactttct catatatttt ttcgatcgtt
    18901 tttttagaaa ggactgtttt tccattttta gtaagtccac ggataaaatt cggatgatct
    18961 aaaaacaaag gatctgattg ttttagatta tcgataaact ttttgctacg caaacgttct
    19021 gtctgctccg atacattttc tcccgtgata cgtttgaaat aagcctcttc accttctatt
    19081 tcctctgctg aaagctgtga aaccagctgt atgatggtta gattcagtgg atttctttca
    19141 cctaatgatg gtaggacatt cgaaatatag tcgataaacc gatgattagg tgatagaatc
    19201 agcaagtcat cggatgtcat cgtatctcga tataaataga gcagatacgc aatacgctgc
    19261 atgatagcag aggttttacc acttcctgct acgccattta ccaagatatt ttgacttttc
    19321 acatcccgaa tgattgtgtt ttgttccgat tggatcgtag cagtgatagc cttcatttca
    19381 ttggtctcat cttggcctaa gacttctaat aatacgtcat cttgaatagc tacagacgta
    19441 tcaaaaaact tgaccaaacg atctctttcc aaaagaaatt gtcgtctttc tttaataacc
    19501 gtatcgattt tattttgacg aaccgtataa gaagatggac caatcatgtt attgtaaaaa
    19561 agttcggcaa ttggtgaacg ccaatcataa acaagatttt catctgcatc atctgtgaaa
    19621 tttgctgtac cgatataaaa ggattctttt ggctcattat ccagaaagtc tacaacgact
    19681 tttccaaagt agggactttt caataaacgt tcgatctttg ctagctgatt ttctgcgttt
    19741 ttctgtttga tattcatctg atcgatttct ctatttttca tttcaatcat cgaaaaagta
    19801 tccaggttat ctaagtaact gtcaaaattc aatcgaagct cgccagccat ttctttcaac
    19861 gactggtttc cttctatttt tgccgtatcc atcgattccc gcagttcgtt ttttttatca
    19921 attagctttt gatacacgtt cttcagatat gcttcttcta actgtttttg tgtgttgacc
    19981 atacacattc tcctcttttt ttaaagtggt ggaaccgatt agtttacctc ttttaagagt
    20041 cgaatgcaag ctttttaacg agtatcattt gttaggatat atcagttctt caggtcggac
    20101 agtttgatat aaagaaaatg caccatcaag gttttttacg tggtagccag actgcttcaa
    20161 gattctttcc gctagatagc tacgtaatcc gctatgacag ctgacgatat attcttgttg
    20221 gctgtctaat tcatttaatc ggtcccgaag ttcattcaaa gggatatgtt tggcttcctt
    20281 gaatttgccc ttttccaatt cttctgctgt tcgcacatct aataaaattt ttccttttgc
    20341 tagttctgtc ggcaattcat gccattgtac ggtttcacta agcccttctg caatgttcat
    20401 tgctgcatat cctagcatgt ttactggatc tttggctgag ccaaatggcg gtgcatacgt
    20461 caattctaat tccggtaaat cgaagatcgt caaatgccct ttgattgctg ttgctaaaat
    20521 atcgatccgt ttatccacac cttttgcccc aacaccttgt gcaccataaa tctcgccagt
    20581 ctctggatgg aagatcaact tcagtaaaat atctgttgct tctggataat agcttgcatg
    20641 atcttttcct gatacatgaa tgacttcaaa agacagttcg ttttctttgg ctgttctttc
    20701 acttaaaccg gtggatgcgg cagtcattcc aaacgttcgt ataattgctg ttccaatacc
    20761 gccttgattt cttcgagaaa ttccggaaat cgtgtccgca acttgtctac cttgacgatt
    20821 ggctggtgaa gcaagagaaa taagtgcatc ttttccagtg atttgctgtt ttacaacgat
    20881 agcatccccc accgcataaa tatcaggaat attcgtttga taacgttcgt ctactaggat
    20941 acccccgcgt atgcctaatt cgattccagc ggtcactgct agctggttat caggacgaac
    21001 accaatggat aaaataacta aatcagcagg gatggtacgc ccatcatcca gtcgcaatcg
    21061 tttcccgtgg tcttcaaatc cagcgacagc atgagaagta atcacttcta ctccttgatg
    21121 agacaattct ttttctataa aagctgccat ttcttcatcc agtgttggaa gaatatgtgg
    21181 tgcttgttcg atcaccatga cttctaaacc tcttcttttt aggttttctg ccatttccaa
    21241 tccgatgaat cctgcaccaa cgatcacggc acgctttggc tgtttttcta atgcatgcat
    21301 cactttatcg atatctggta catttctaat agaaaaaaca ttgtcggctt ctgttatccc
    21361 tggaatcgat ggaacaactg gttttgcacc aggagataaa accaatgcat cgtactgttc
    21421 aatgtgtttt tgaccctcat gtacgacttc taccgttttg ttttcgggaa agatggctgt
    21481 cacttcatga tttggacgca catctaaaca aaaacgagcg gataatgatt ctggcgtttg
    21541 gacaagaaga ttttcccgtt cactgatttc tcccgaaaga taataaggca agccgcaatt
    21601 tgcaaaagaa acatacggtc ctttttcaaa aacaacgatt tctgcatctt ccattaatcg
    21661 gcgaagccgt gtagcagcag acattccacc tgctacacct ccgacaataa cgattttcat
    21721 cttatttccc tcctactgtt cgatcaaacc attgattcat gccaccacgt acattcacta
    21781 catcataacc agatttcttt aattctttag ctgcttgttt actcctcatc cctgattgac
    21841 aaatcacata gacggtcttt tctttgtctc catcatatct gtttatactt tgtaatggaa
    21901 catttttagc tccttttata tgcccgcccc ggtattctgc aggtgttcta acatcaagta
    21961 acgctggatt ttccaaaagc ttttccttta attctgggac tgttatcgat tttattgatt
    22021 gaaatagcaa attcattttc tgcacctcat ttacattttt ataaatacct catggggtat
    22081 attaaacagg agctttatta atatgtcaac cagaatgact cttcattttt ttcactactt
    22141 tttatatttg cataaaatac cgataagggg tattatctaa ttataaaaat agaggagaat
    22201 gtgttatgga gattgataat aaaaatatcc tgaaccgttt gaaacgtaca gagggacaaa
    22261 ttcgtggtat ccaaaaaatg atcgaagacg aaaaagaatg tatggatgtc atcactcaat
    22321 taagcgctgt tcgttctagt attgatcgcg taatgggcat gatcgttgca gataatctga
    22381 aaaattgctt tgagaaacct gatagtaatc cagaagaaca agcggctaaa ctagaacaag
    22441 cgatcaagat gattattaaa aagtaaagga atgatttcaa tgaaagtcgt tttccatatt
    22501 gatgaattag aaaaatggtc agaaacaggg aaaaacgtaa aaaacctgat aaaagcttct
    22561 ccagaaacga cgattgtcgt atctgtaaat ggcatcgcga ttaccggtta tctagactct
    22621 gccaatgcag aattcttaga tttgcaagga gtcgtttttc acgcttgcgc caatgctatg
    22681 cgtgctaatc atatttcaga aagttcttta cctgaacaag taatcgttgt accagcaggt
    22741 gtccttgatt tagttgaact gcaatcccaa ggttatgctt atatcaagcc ttagtcagta
    22801 gaggttgcga cagaagtgat cagcttcaag aaatttcggc ttatttttcg aagaagctac
    22861 ttctggaaaa ccgtgaatca aaggttgtga aaacgctgtc ctgcatcaag taataagaac
    22921 agccaaacaa aaatagcttc tcatattttt cgtttggttg ggcttattac cgcagatgca
    22981 agcttttgaa caccgtttaa ggaagaggtt gtgaaatcag cggtttgacc taagtattag
    23041 agaaaaaaac gggaaaatag ctcctcatat tttgccgttt tttgagctaa taccgaaggt
    23101 cagctgattg aacaccgttt aaggaagaga ttgtgaaaaa gtcgcttagt ttcgagtatt
    23161 aagaaaaatt ttgtgaaaat ggatttctac atttttgcat aaatttggct taataccgag
    23221 aaactggctt ttgaataccg tttaaggaag aggttgtaaa atcagcggtt tgacctgagt
    23281 attagagaaa caaacggaaa aatagctgct catattttgc cgttttttga gctaataccg
    23341 aaggtcagct gattgaacac cgtttaccaa gaggttgtga gcctaccatt taactccgaa
    23401 tcacaagaaa taatttcaaa aacaacttct cctgtttttg gttcggttgg cttattatcg
    23461 agaagtagct actgggagtc tatttatcaa aaaaaggaat gcgacatagg tcacacccct
    23521 tttttatttt ctttgaaaca tctttcggta ctcgacagca tacaagacaa aagattgtaa
    23581 aagaccgtaa gtgatgacgg caaaaatgac tctcacccac agcgttggta attctgggaa
    23641 aagcagcaaa aggatcatgc caacatagat gacagcagtc gctactttgc cataccactt
    23701 cgctccactt aatttgatat ttttagatag cccgattaat ccagctacaa acataaagcc
    23761 ttcttttatc aagaatagac caaacaacag ccaaagccac ggtcgatacc atgccataga
    23821 caaaatcaga aaaagttgtg tcaatttatc tgcaaacgga tcaagcacct tccctaagtc
    23881 tgttacctga ttatatctcc gagcaatgac cccgtctaga taatcagaca aacctgagac
    23941 aacaatgacc gctcctgcta tataaaatga ctgtctcagc acaaaataaa gataaatcgg
    24001 cagcaaaaaa atacggaata tcgataaaag attcggaatc gtttgtattt ctttacgcca
    24061 gtctgtgctt aatttcattt tatcgcccta cctcctcagc actcttttct ttttatttta
    24121 gcttacacgg ggaataaaac caatgatttc actgttttta tttttcttta cagacactga
    24181 tattatgagc taatttgaga taatcacttg ctgttttcat cgtttactct tctttcttcc
    24241 tgtcgtttgc gcatttcttt tactagtact ttatgagctt tttttgatcc tcgctctagg
    24301 tcacgctgcc gtttacgtgt tttataatcg ataaacagac tgtctaaatc gtaacctgtc
    24361 gggtacagat cttctgctga acgcaccaga cgaacacgct gacgaggcac gtggattatt
    24421 tttttgtcta aatatacatc aatcgtatct tcacctatat cttcataaac taacgcttct
    24481 ttttggtatt cattgacaaa tatccgatca ccttttgcaa agagctgacg ttctttttta
    24541 ttctccttcc tatttgtaac tgctgtctta ggaagaaatt cttttttctg tgtccgatag
    24601 gctttttccg ccaagtaacg ctctgcttga tggatcaatt tcatcgacat atccatttta
    24661 tgagcaatcc acaaagcttg gctttctcct gtttcttcca acccgcaact gatatttagg
    24721 acgaagtgct tcccgatcga aagccatagc agccggcaca aaatcttcat gatctccggc
    24781 gaatttcttg atttctccat aatgggtcgt ggcaatgatc aatgcccctt gctcatacat
    24841 agattccatg attgcgatcg ctagtgcagc cccttcattt ggctctgttc cactgccaat
    24901 ctcatctaaa agtaccaacg tattcctttt tatctttttc aaaatagcag cgatgttttg
    24961 catatgacca gaaaatgtac tcaacgcatt ttctaaattt tggtggtcac cgacatcgac
    25021 gaaaatctca tcaaagacag caagctctgt cccttctttt gccggaactt gcataccgaa
    25081 catcgccatc aaagtcaata aaccgactgt cttcaacacg actgttttgc ctccggcatt
    25141 tgctccggtg ataatcaagc ctcgatagtc tttaccgatt tcaacatcca atggtaccgc
    25201 atgctcaggt aaaaatggat gtctgccttg cttgataatg atatgttccg atttattgat
    25261 tctaggtgtg cttccattga tttctcggct aaattttgcc cgagcaaaga tgatatctaa
    25321 caccgtgatc gtttcgatca ataaatcgat cacttcttcg ttttctgcga tagcaccagt
    25381 caatgccgcc aggacttgat attcttcact gatttcttca gcttttaaca actgatagtg
    25441 ttcattcaat ttagaaatca cagttggttc aataaaaacc gtcgttcttt tatttgattc
    25501 atcgataatc gttccatcta ttttattttt atagctggct ttgataggaa tcgtatagta
    25561 ttcgcctttt tgaacaatca ttgcttcttg gatcatttct ttgtttttcg gatgacgcaa
    25621 gaatttcagt aattttgact ggatttcttt ttcgattagt tgtaattgtt tgcgtacttt
    25681 acgcaaatta cgtgacgcgt cgtcactgac tttattattt tttattttct ggtcaatcaa
    25741 ctcttctaca tttatcaaat caggaagatg tttgctataa gcaaacaaca agggtgtctg
    25801 gtattgattc ttatcaaaaa actttgtgat catccgactg cttctaagaa aatccgcata
    25861 ttcgatcaaa tcggttggct gcagaatcaa cccttttttg acttgttctg tcagtgcatc
    25921 gatcctcggc aaccccataa atggaacatg ctgactgctt tctaagatca agcgtgcttc
    25981 tcttgtttct tcttgacgat ccaagacagt ttgtaggttt gtcgagaccg tcatatcgct
    26041 gattcgtttt ttgctatagt ttccaattgc tcttgcttgg atttcctttt tgatccgatc
    26101 aaattgtaat tgactaatca tttcgttgtc catattctct ccttttcttg aagagatacc
    26161 tgtcccaaaa taaataaggg cctagagata aataaaagga tagaacacag cttaaaaaag
    26221 tcatgtccta tccttattag aatacaaaga tattgttttc ctgacaggta ccgtttcata
    26281 agcacaccaa ataaactttg tttattggct attcgactta ctgattagat accagctaca
    26341 ctcacaaaac ataccccatt cttctaggtc ttatttattt tccacttaac tatagcaaga
    26401 cacattttgg ttgtcaaact ttagtatgtt ttatagattt acaccattaa tgaatagaca
    26461 cctaccgcga taattgctcc gatcattgga cctgcgattg gtacccatga atatgcccaa
    26521 tctgaagttc ctttattagc tattggcaat accgcatgtg ctaatcgagg accaaagtcc
    26581 cgagcagggt tgattgcata tcctgttggc cctcctaatg aaagaccgat ggctaagatc
    26641 aatccaccta cagcgaatac gttcgttcca ggtgcaaatt cgttttgtcc aaaagctagc
    26701 aacccaagaa ctaatacaaa tgtaccaatt aattctgtga tcacatttgc tggataattc
    26761 cgtatagcag gacctgttgc aaacgttcct aaaatcgcgc tttcatcttt cgttgcattc
    26821 caatgtggca aataagaaag ccaaacaaga atggcccctg caaaagctcc taaaacttgc
    26881 gcaatgatga aaggaacgac aagattccaa ctaattgccc ctgtcatcgc catagctaga
    26941 gagactgcag gattcaaatg agctgggccc atgaatccag aaatatagac agccattgtt
    27001 acagcgagtc cccaaccaaa tgcgatgaca atccagccag aagcctgtgc tttacttttg
    27061 tttaaattca cagccgcaca cacaccatct ccaagcaaaa ctaggatcag tgtcccaata
    27121 aactccccca tgatttgagt catatcactg ttcatttatt tctccccctt tagttcccgc
    27181 agatctgatt ctgcaatcaa tgcttctaaa cgtttagtct gttgcgcctt ctcctcttct
    27241 gtccattcaa aatatccagc aattgcatcg atcacaggtt gcttgatctc atcaagctga
    27301 tctcgttcaa acaacagatg atttgtacga cgaatgagat aatcgcctgg ggccaaaacc
    27361 atttcttctt ctaaaccata acgtaaccga gctgactcag cgagactcaa accaggataa
    27421 ggtgccattt cttttgctaa ttcaaagata cgtcgggcat tagtcccgta aaaatcagcg
    27481 atataagtag catcttcttc ctctaaaccg gctgctactc cttcttttgc taattctgtc
    27541 actgtttctt ctaatttagt tggatcgaag tttccacctg aaatctgata ttttttagag
    27601 tcgatttctt tcgtctctat tccgtattct tcttttaata attggcgtat caatcgcaaa
    27661 gctccttctg ccatcttacg gtaatcggtg attttcccac cagataaagt cagcaaacca
    27721 tctggttctc tttctaaaga actacctctg gaaatcgtag aaggtgcttt ttcatcacgg
    27781 ctgttttcca aatggttcaa cacgtcttct acttcagcac gagaaacttt gttttcctta
    27841 tattcactta ctgtatcgac aactttattg aagctcttgt ctgaaatcga tccattatct
    27901 ccaccattgt aatcagaacc agaattacca atcaacagtg gacgaagtcc tgcccagctt
    27961 gcttcgatat cattcaatgt gatatttgct tctggatagc gatgattgat cacatccaat
    28021 agataatcta catcttcttg tgtgactttc ggatccgtaa aatctccttg gtaatccgta
    28081 tctgtcgtac caaagtaagt cttgttttct cttggaatag caaaaaccat ccgcccatct
    28141 tgctttcctg tatcgaagta tgtgggttgc ggtacaggca gttttttcgc atctacaact
    28201 aaatggatcc ctttagttgg acgcatttta ggagagactg gacgcgtaaa attcaagttt
    28261 cgtactttat ctacccaagg accactcgta ttgatcacta attttgcttt gatttcgatc
    28321 acttcatctg tcagcaggtc acgagctttg acgccaacga tttgatcgcc atcatataaa
    28381 aagccaaccg ctttcatttt acttactaga taagccccat cttcggcagc ctttttgata
    28441 ttatcaatca ctaaacgggc atcattgttg cggaaatcta gatagacacc cgcgcctttt
    28501 agcccttctt ttttcaaaaa cggttctctt tccaatactt cttctggtgt cagcgtataa
    28561 ttctcatatt tggttcctgt cacatttgcc agtttgtcat aaaggtccat tgctactttg
    28621 accgagaaca tattgaaggt tgttgctcct tcgccctcat agattggcaa aagcattgga
    28681 tctggttttg ggatgtgtgg ggcaatactt tgtacgactg cacgttcacc aactgtgtca
    28741 gctactactt ccacatcaaa tgtcttcaga taacgaatac cgccatgaac aagtttggtc
    28801 gagcgagagg aagtcccttc tgcaaaatcc tgcatttcga tcaatcctgt tttgattcct
    28861 gatgctgctg actggactgc cacaccggca ccagtgattc cgccaccgat gatcaacaga
    28921 tccaattctt cttgctgcat tttttgaatg ctatcttgtc ttgtcttgtt tgaaaacata
    28981 tggatttcct ccttattcaa atgcttgggt agcttttact gcttttttcc aaccgttgta
    29041 aagtttttct cggcgctctt cctccatttg aacttcaaat agcttgccag cttcataaaa
    29101 ttcgcggatc tcgtctgtat ctttccaata accgacagct aatcctgcta aaaatgctgc
    29161 ccctagcgcc gttgtttcca agttttctgc tcgttggatc ggtacattca agatatctgt
    29221 ttggaattgc atcagatatt cattgtttgc tgcaccgcca tctactttca atacaggaat
    29281 cttgattcca gtgtcatctt gcatcgtatc gatgatatct ctcacttgat aagcaatcga
    29341 ctgtaaagta gctttaatga tatcttcttt tgtcgtacca cgtgtcaagc caaacatagc
    29401 ccctcgtgct gcctgatccc aataaggagc acctagccca acgaatgcag gaacaacata
    29461 aacctcatct tcgcttgtag agcgtttcgc tgcgtcttct gaatcgctag ctttttgcaa
    29521 catttgaagt ccatctctca gccattgaat cgaagaacca gccacaaaaa tacttccttc
    29581 taaagcatag taaacctttc catttatgcc gtaaccaatt gtcgtcaata aattattttt
    29641 ggataattgc ggtttttcac cggtattcat gacaataaat gaacctgtac cataagtatt
    29701 cttgaccatg cctggttcga atgccatttg tccgaataat gcggcttgct ggtctcctgc
    29761 catccctgaa attggtgctt cgcttccata aaaatgataa ccttgcgtat aaccataaac
    29821 ttctgagtta gaagtgactt ttggtaacat cactcgagga atatttagta aatctaaaat
    29881 ctcctgatcc caatctagct gatggatatt gaacaacatc gtccgactgg cattcgagta
    29941 atcagtaaca tgtgcttgtc catcggtcag tttccatact aaccaagaat cgatcgttcc
    30001 aaacatcaat tcgccttttt cagctcgttc ttgcgcgcct tctacatgat caagaatcca
    30061 gcgtatcttc gttgctgaga aataggcatc gatcactaac cctgtttttt cgtggaaaaa
    30121 ttcttgatag ccttcatttt ttaagttatc tgcaattcca gctgactgtc tggattgcca
    30181 aacaactgca tgatagattg gacgtcctgt atctttttcc catattactg ttgtttcacg
    30241 ctggttcgtt atgccaatcc cagcaatctg atttggtttg atccctgatt cgatgaacgc
    30301 tccggcaata actgactgta cagaattcca gatttcattt gcatcatgtt ccacccaact
    30361 ttcttgcggg aaatattgcg tgaactcttt ttgagaactg ccgatgtgtc ttcctttctt
    30421 gtcaaagata attgctcgtg agctagttgt accttggtca atcgccatga tatacgttga
    30481 ttctgtcatt gtgattccct ccattatatg caaacgcttt ctttaactac tcttatcata
    30541 ctactgtttt aaaaaaagaa actgtcaaaa ttttattctt tttttctttt tttgacagtt
    30601 ttttattatg aagctatttt ttaatcaatt cttttctttt ttcagcgtct ctattcttct
    30661 tttcaatcga ataatgtcgt aaggtgacgc aaattctgac agataatatt cacactgttt
    30721 tttgtttctc tggcaaaatg tgatcaccaa atcatattct ttaccttctt cataacttcc
    30781 aatctcaata ccgccgattc ccctcagttc tctgatcaga tattgttgaa aagcaatacg
    30841 ataaatcggc agactttcta aatcgattcc aatcactact ggttttgcaa tataaaaatc
    30901 gatcatcaaa agaacattgg catactggat catcaggtaa ctaagctcac tatcttcagc
    30961 tcttttcctc ggcaattgct gcaccgctgt ttcctgtaat ttcgccagta actgtgttaa
    31021 ggaatgcccg agcattttct gctgctgttc caaaagccga tcacgctcat agacttcgat
    31081 ctttccaaca aagaaaaacc attcattgtt gatctgggaa atttggtagc ctactgcctt
    31141 ttcttctttg attttcaaac gacgaggacg ataatgccat aacatcgttt cccgaatgta
    31201 agtatctaaa acagcggttg gtaacttttt gctccgtgtc aaatcatact gataaaatat
    31261 ttcttcgtct actatcgaaa aagaaacaaa aaagctgtaa aacatcattg tttcgtatac
    31321 attcagttct gctgctgttc gactaagatg catcacgatg attggatcga ttgcttgata
    31381 aagccggtcc gactgataga gtaatttctt ttctttcaaa gttgcgtacg tacttttttc
    31441 attcaatagt ctttttttcg taatcccgag ccagcaagca atctgtgctt ctgctgatgc
    31501 cgtaaacgtt gtttctaata cacggtccaa tcctagaatg aacggtcttt tttctggtgt
    31561 attttgcaaa aaaagcggtc gctgatcttc cgggatatat tggaatagtt cataataaaa
    31621 atatcgtatc tgtagctctt ctccgtataa ttgaccgttt ttgatttgta atccaaattc
    31681 ctctaagagc tggttcaatt ctttgatctt tcgaaaaaca gaagactcac tgatattaaa
    31741 cgctgtcgct aatcgaacga tggatacttg ctgatgttct aataaataga cgagcatctt
    31801 aaacttcaag ctttcctgca ataaaaacaa tagaattttt tccaaactta catcttcgtc
    31861 caacacaagc agcgcctgat actcatttcg ctgtacttct actttttttt ccatcattcg
    31921 gccaatcaat tcaatatctt ccaaatattg atcaaacgag gcttttgaca gttggacatg
    31981 ctctctcaaa ccattgatag aggctgttcc cccttgcaga acaaggtttc gcaaaatcag
    32041 gatctgtaac tgctcttttc tttctaataa tgcttcaatc ttcataggca gtattcgcca
    32101 cctttgacca caccatatct ggcacacggt attctggctg gaaaaatagc tcatgttctt
    32161 ctaactgttc aaacgtccat ccttcttcta ctgcaattgt cagttggtca agaaggtgga
    32221 acatctcttt tttgctttgg agctgtgctc caagaatctt tttttcagaa tcaaatagaa
    32281 atttgagttt aactttgctt tgatttattg ctgtaagctt gtagtctacg tatcctgttt
    32341 caattttttg gggataaaaa atgctctctt cttctgtcaa acctacgctt cctaagaaat
    32401 agccaaacca ctgattgccg actggacgat aggttccctg atcctttgtc tgtgagccac
    32461 taattgtctt gctgacattt cgtgctgtac ggacagcgtt atttactaga gaaacataca
    32521 ttttttcatt tgttggacga aaagttactt ggatcgcatc gccaatcgca taaacgtctt
    32581 tttgagacgt ttgcaagtag tcatctaccc agatcgttcc atcatcattc aatgttaatt
    32641 gttcttccca catctgattg tcgggacgag aatgattagc cagcaaaaca agatcatagt
    32701 tctcctttct tttttccgtc tctacaatag cggtttcatt ttcggtcaaa gacacaactt
    32761 gttcttctaa aaaaagtgaa agcccttgat ttttcatttc ctttactaac ggttctgtca
    32821 tttcaggatc tagataacga aaaagaattg actttcggct ttcgtaaaga tggatttgtt
    32881 tttttcttga tgccaaccct tcagctattt cgattcctgc ttgtcctgca ccaataattg
    32941 caattttctt tgcattcatg atcttttgct gaagagccgt tacgttttgt atctttttaa
    33001 ctgggtgaat aagcgttgat tctgcagaaa tatttcgaaa cttttgattt gaaccagtcg
    33061 ctagaatcaa acgatcaaaa tccaattttt ttcctcctgc taaaacgact tttttttctt
    33121 tcaatcctat tactgtcttt tctgtgtaaa catggattcg atagcggtca gtcagttctt
    33181 ctttcgtgat ccaagaaagt tgtttttcac tggtaacctt tccttttaat atcaaattga
    33241 acccgctggg aatccatcct aacttcgatt gcttttcaat caaatatatt tcacttgttg
    33301 gcatcaattg gcgaagataa atagccgcat gaatccctgc aaacgacccg ccgacaatta
    33361 caatgttcat ctgcattcct ctttcttata aggtgttcta ctgctaactt ctcaatcaga
    33421 aaacacagta ttcataactc gctttcaacc ttatgataca tagcgatgca gcagaatcaa
    33481 ccctctccat cataccgtgt tctaggtctg cttctcaata atgtactagt ggacctaatt
    33541 gaagagtatc atttctgaag agatgtttca aaaaatgtac tcttataaaa gaaaaaaact
    33601 cgccttttac gtacctctgt ccaaatagga aacagaaaag aacgaaaaga cgagttttag
    33661 cgtgtgtaat gtaatagtta gaatagacac atcatttatt tttaattctt taatgcttca
    33721 acaactgctt cgcctaattg atgagcagat tgaggatttt gccctgtaag aagccgccca
    33781 tcaatttgaa ccacttctga aaaagctgct ccagactgat agtttgctcc tttttctttc
    33841 aaagcatctt ctgctaagaa tggtacttca ttcgttgtac catttgcttc ctcttcttca
    33901 ttactgaacc cagtcactgt acgtccagct aaaatagatt ttccagactc atctgtaact
    33961 ggcaacaatc ctacaacacc gtgacaaaca gctgagacca gcccttcatt tcgatagatt
    34021 tgtgaagcga ctttcccaag atctattgct tctggaaaat cccacattgt tccgtggcca
    34081 ccagcataat aaaccgctgc ataatcattt gcatccacat catcaggacg taaggtattt
    34141 cccaaggccc gatttctgaa atcttcatct tcataatagg cccaatcgat ttcatccata
    34201 ttcaaaacac tttgcggttc taaaggtaca tatccgcctt taggactgac aaaatctgca
    34261 tcgatcccat tttttactaa tacatcataa aaatgagtca gttcacttaa ccacaaacct
    34321 gtaggacgct cgatcttttc gtacttttct acatttgtta atacgatcaa tactttcatt
    34381 ttcccatcct ctttctataa aaattgcgtt attgataacg tgctttcaag aaattatata
    34441 atgggcttgg caaataaagc tctttatatg cttcttcaaa aggtttcgtt acaaattcat
    34501 cctcacggtt ttccaataat ttctctgccc agtcaggatc gacgatcatt tgctgtccaa
    34561 ttgctgcaag ttctgcatat ttcaatacct gctctacatc ttcgcgattg cggatcccac
    34621 cgacaccaac taaagggatc tttccttgaa tcgtgttatg gaccacttca agaatcgatt
    34681 tatcgttgta tttatcagaa cgagctattc gatcatacat atttaatgaa acatgcagat
    34741 aatctagttt tgactcacgt aatcgttcaa gaagccagat cgtgtcttca aaacggatac
    34801 ctggtgtttc atattcttct ggtgagaaac gataccctac gatgaatggt tttttagcat
    34861 attgttcaac cgctgagaaa accgttgtta ataattcttc aataaaacga taacgatttt
    34921 ccaagctacc gccccattga tcctctcgtc tattcgaatg cggagagaaa aattgttgga
    34981 tcaaatacgt atttgctcca tgcaactcga ttccatcaaa tcctgattca atcgctctac
    35041 gtgtggcttt gccaaatgct tggattgttt caacgatttc ttcttcactc attgctcgtg
    35101 gtgtttccgc atcaggacgt tttgctgcaa ctgcacttgc agatacaggc tgttctccag
    35161 ataaagttgc tcgacttgtc attcgtccac cgtggaaaat ctgaataatc gcttttgcgc
    35221 cttctccttg gattgctttc gctagctcac ttaatcgagg aatcatttca tcatgagcga
    35281 tgctgagttc acctggccag ccttttccga tatcttggac atttgcagca ccagtaataa
    35341 cagcaccaag acctttagaa cgttgtttat aataagtgat ctcatcttcg gtgatcactc
    35401 cattgaaaaa gctgagttgt gtcgtcatag gcgacagcat caatcggttc ttcaattgaa
    35461 ctcctgaagg taaagtaatt gattgatcaa attgtgacat tgtcattcct cccataattc
    35521 gctctgatta acctatcgag aatcatctat cattaaacca ctcgattagt tgtacatgca
    35581 actaatttgc ttaaaaaatt ttattttttt tgtaacttat ctgttgcatc attcattgtc
    35641 tgggctaatt ctttacttgc ttcatttccc aaaactgctt tgtatgactg atgaagttct
    35701 tcccagctac catcgacttc cttagcaaat tggcgtcctt gttctgtaag ataaactaat
    35761 gacaagcgac cttcgctaac tgttttgacg tatcctttat attctaattt ttcaacaaaa
    35821 cgagcaatcg ttgatggggc ggaatagagc atttgtgcaa tatctttttg tggtattcca
    35881 tctttttctt ttaatatcaa taaaataaaa ccataagttg gtgccagacc tgtccttcta
    35941 aacgcttcat cagctaattt attcaacatg cgatctagct ttttcacgct aaagaaaaga
    36001 cattcatcta acgctttttc aattggcttt tccatttcat cccctccatt ggcgtacata
    36061 tcatagtatg atttttattt tttgtcaaaa aacacggaat aatgtccgcc tcctctgtct
    36121 agatttgaaa aaaagaagta gccatcttca aagaatttcg gcttgttttc gacaaaactc
    36181 cttctggaac accgtgaatc agaggttgtg aaaaagtcgt ttagttttga gtatgaagaa
    36241 aaattttgtg aaaatggctt tccacatttt tgcataaatt tggcttaata ccgaaaaact
    36301 ggcttttgaa caccgtttat atcagaggtt gtgaaaaagc cgtcctgcat caagtaataa
    36361 gaacagccaa acaaaaatag ttcctcatat tttgtcgttt tttgagctaa tgccgatggt
    36421 cagctgattg tacaccgttt attgagaggt cgtgagcctg ccgttgaact ccgagtcaca
    36481 aggagcaatt tcaaaaaaca gcttctcatg ttttatgact atggtgactt gtgatcgagg
    36541 agttggcagg agaatactgt ttattcgtaa agaaggggct gtgacaagac ttttgtcaca
    36601 gtcccttatt tccttttatt ataggatttc gccatttgat tggatgactt gtctgtacca
    36661 atcaaatgat tttttcttta accgtttctt tgtgccattc ccttcgtcat cttgatcaac
    36721 atagatatat ccataacgtt ttgacatttg tgaagtagaa gcgctgacga tatcaatgca
    36781 gccccacgac gtataaccaa ataaatctac tccatctttg atagcttcct tcatctgctc
    36841 aatatgctgc ttcaaatagt caatgcggta atcgtcttga acggttccat cttcttctac
    36901 tttgtctata gctccgagtc cgttttcagc tatgaacagt ggtttttgat acctatcata
    36961 taattgattc aaagcaattc tcaaaccctt aggatcaatc tgccagcccc attcacttga
    37021 tggaagatac ggatttttaa ttcctccagt tattaagttt ccttggaccc cttcccaatt
    37081 ttctggatga gcactgactg cactagacat gtagtagcta aaagaaacaa aatcaacagg
    37141 gtaggctgct aagatttctt catcacctac ttctattttt aagttgacac ctttttcttc
    37201 aaacattcgt tgcgtatacg ctggataata tcctcttgct tgaacatcac taaagaacaa
    37261 agaagttctt tgctgctcaa ttgttttttg aatatcatcc ggatcacaag aatacggaac
    37321 aagaagctga tagctgatca tacaaccgac ttgtgaacct ttgataattt catgacaagc
    37381 ttttgtagct aaagcacttg ctataaactg atggtgtgca ccttggtatt tcgcttgttc
    37441 caaatgggga tggttttctt caattactcc tacgctaaca aaagggtgat gttttacaca
    37501 gttgatctca ttgaaagtca tccaatattt tactttattt ttatagcgtt tgaatactgt
    37561 ttcagcgaaa cgaacgtaaa actgaataag ctttcgatta ggccatccac catattctgt
    37621 aaccaaatat aacggcattt cataatggga aagagaaacg actggctcaa tcccatattt
    37681 tagacattcg tcaaacactt gatcataaaa aaataatccc gcttcattgg gtgtttcttc
    37741 atcaccatga ggaaaaattc ttgtccatgc gatagacatc cgatagcatt taaaacccat
    37801 ttcagcaaat aaacggatgt cttctttaaa gtgatgatag aaatcatttc cgtgtctttt
    37861 aggataataa tacttgctgt tgggatcctg cgccgctttt acttgctgat gcgtcatcat
    37921 atgccattga tctgtccatt tttctttagg taaatcgctg tcgaatgtat acacatcaga
    37981 cacagataat cctttttcat ctacatccca tgcaccttca cattgattgg ccgctgtcgc
    38041 tccgccccat aaaaatcctt ctggaaattt tttcatatcg atccccctaa acttgctagt
    38101 tttcttgttt gattattttt cttatgacta gtaatgatat ttttgaatct actactattt
    38161 gtaacaataa ccattgtggt cggatcatat ccctctttga ttaattcttg caaatctact
    38221 tccatcaata aatcgccttt acgtactttt tttccatcag atactgcact ttgaaagtat
    38281 ttgccattta aattcactgt atcaataccg atatggatca gtatctctgc tccttcttca
    38341 ctgactaccc caattgcatg tttcgttgga aaaactgttg aaacttcccc gtttacagaa
    38401 ctgtagattt ttccgtccgt tggaatgatc gcaaaccctt ctcctaaaga tccactagca
    38461 aatgttggat cgtttacttc agataaatca attatttcac ctgctgcagg agtacttaac
    38521 actatatcct ttgaggattc ttcttcgatt tcatccttgt agccgaaaag aaaagttagc
    38581 atacaggaac tgatcatcgc taagaaataa ctagcaacta gccaaacaaa tccttcacca
    38641 atataaatcg ggaaagacaa aatacttctt gtagcaactg ccaaagcacc ggctcctgcg
    38701 gcaccagcta ctccaccaaa tatagctcca catatacaag caatgtaaaa tggtcgttta
    38761 tatttaagag tcacaccata aacagcaggt tcagtgattc caaataatgc tgtgataaat
    38821 gcagataaag ataaactttt tactttctta tttttcgttt tcaaaaatac cccaagtact
    38881 gctcctgctt gcgcagctac ggcagtcata catgctggac ctagcgtatc acgaccgtag
    38941 aaagaaagat tgttggtcat tactggtaca agtccccaat gtaacccaaa aatcactaac
    39001 acttgccaaa atccgccgat aacagcacca gataaaacag ggctaaagtt ataaacagct
    39061 aaatatccag ctgcaatcag ctgacttgca taatctgcaa ttggacctac aactaataaa
    39121 ataattggga ccatcacgat gatacaaatg aatggtgtca ataaatttcg aatactttcg
    39181 tgcaagcttt tgcgaatctt aggctcaata taagaaagaa cccatacagc taaaattgct
    39241 ggaataaccg tacttgtata ccttgctaga atcacgggca tccctagaaa tcgcaaggtt
    39301 atgctatcac tatatgcact gacaatcgta ggataaacga gagctgctgc aataaccata
    39361 gcgatgaaac gatctgtatt gaactttttt gcagcagtat atgccaaaaa tataggcaag
    39421 aaatagaaaa atgcatcagc tgctgcattc aaaatgatat aagttcctga ttcagtagtt
    39481 aataaattca aactcgtaca taaggcgagt actcctttga tcaaaccact tcctgccaag
    39541 acgcctaaag tcggggcaaa aacagcggcg atcatgtcta taaaagagtt taaaatgcct
    39601 tttttctcag ttcctctctt tccactagat gcatcatctt ctagtttcat ttgtttggat
    39661 aatacgtcat acacttcatt tactgcattt cctactacga cttgaaacat tcctccagct
    39721 tcgactacag tgatcacacc ttctagttgc tctaccttct ccttatctgc cttcttatta
    39781 tcttttaggg taaagcgtaa ccttgttgca caatggtaaa cattgctgac attttcttcg
    39841 cctccgacaa atcggacaat atctttcgct aattgtgaat agtccatttt tacttccccc
    39901 ttgttaatta atgccgtagc aatccttctt acaagataag tatagttctt agaaaacggt
    39961 ttctccattc aattagtacc ccttctaata gcgaacgaaa ctgtacaata gtgtgtatgg
    40021 tttacttagc cgagcaaatc actcactgct tgaaagaaaa caagtatatc gtttctctta
    40081 tagtcaaagg agacaaaaaa aacacgcttg atcttccttt gctgatgtat aagtggtatc
    40141 tcaagctgat actctgtgat ttttgtttct acttggcttt tgataagaca gcacaacaaa
    40201 gtctcggcat ttaacggaag cataactagg tcagaactag gagagattag ttgctgaatg
    40261 gaatctatct ttttatggat ttttatttga ttttcttctt tgtagtaatg atcaagcagt
    40321 tttgttttct ttttttcttc aactatggtc agcttttcac gcaaaatctg ataaatctcc
    40381 caagattcaa actcatctag aacactaggt agataaatca aatcatccca ctcaaaaata
    40441 agctcttgct cagtagtcaa aattgcatca tattccgtta ttttgtttga ttgatttttg
    40501 aaaagataca ctggttctat ccggcattct ttgatccaca tgttcatact ttgttgaatc
    40561 tgttttttta gtgtattcaa aatactaatt ggctggttac taacaatcag tatctcccct
    40621 tgttttcgaa aaggattcaa cgcttcggca agatacaaaa caaaataagc gctttcagct
    40681 aaattgggac gtaattgaaa atgtattggg aagaaacgcc gaattaaata aatttctaaa
    40741 ggataacggg agatgatctt ttgtacaaaa tgattcatgg tattatgtcc ggcatccatc
    40801 ctcgttttca tttgtttgat atgggttagc aaaaattctg tttcatggaa caataacgaa
    40861 acaggaagat ctaaaaaacg aataatcgtt tgctcaaatg ctcttagatt cttctctatt
    40921 tctttgtttt tttcatcatt aatcatcaaa taatttaact ctaatagtcg attttcaatt
    40981 gcttgttttt cttgattgga aaaagaatag ggtagttctg atgataactt ttttgtgagg
    41041 gtctctacca tcggaataaa taatgtatac ctgtttgttt tttctaaaag ttcttctctt
    41101 cgaagaatgg tcaaaacgag ataccgagaa aatcgtatga agtcctctcc tgaaacaata
    41161 taattatatg atataagaac ctcttttaat gtcttttgga cagtcggcat gatattggaa
    41221 aaaattgtac tgatttgttg aggaaacctt gcgtgttgga tcaccgtttc tgttccaaca
    41281 agagataaga aaattctttt tgaattttct tcagcaatga tttttagtcc ttttgtcgac
    41341 gaaacttcca gttctaattt aggattgcgc tcgatccaac gcaaaatcgt ttttatttgt
    41401 aatgatacgg ctgtttttga aagaaagaaa atgtctgcta tcttttgcat actgacatac
    41461 cctttttgaa acaataagta cgtcacaata gttgaagctc ggaaatccat gctggaatag
    41521 attttatgtt tcgtcacctc ttgtatgatt tgctgtttag tttcagattc aattgattct
    41581 aaaaaataac ctgaacgttt atttgactgg ataatgattt tcttctcgta gatagcaagc
    41641 atatttttga tttcagtttg gatcgttttc ttgttggtac ctaaagcttc agctaattct
    41701 tcgcttgtta tccaatgatt cttatttctt aatactacaa gaatttggag ttgtcgttta
    41761 tttaagtcca tttgcttaca cctcctcttt gttataaaca tacaggaaaa acctctcaaa
    41821 tgacaatagt cacttgcaga ggtttaaaaa tcatttgaag aaagatctat attcaaggtt
    41881 tttaccatta gactggataa tttgtttata atattcaaaa ctatcttttt tcaatctcct
    41941 aaagcttccg ctcccatcat tttgtctatc cacataaata aagccatatc gcttcctcat
    42001 ttcccctgtt cctgccgata cgatatcgat tggtccccac cataagtaac caatgatttg
    42061 gcaaccatct tttattgcct cagcaatttc ctgaagatgt atttttagat actcacaacg
    42121 ttttggatcg tggattcgat tcaattcatc tggtgcttca tctagtccaa tgccattttc
    42181 aactatgaat aatggtaatt cataacggtc tgtcaattca ttcatgacat aacgaaaccc
    42241 tagaggatca attggccaac tccaaggttc gggagatttt tccttcaaaa agggattatc
    42301 gaaaccattt gctccgccag tatctacgcg catttctgct tcttttttat agacagcgct
    42361 acgataataa ctaaatgcaa tataatctgc cgtgttagct tgcaagcact gttcgtctcc
    42421 atctaacatt actggtgcac agtcttcttc cttccatgtc ctgtaaatat aagctggata
    42481 atgccctcgg cacatgacat cggagaaaaa ccatgaattg cgtttaaatt gcagtgaacc
    42541 aaatacattc tctggatcac agtcatatgc ataagtcgct aatgcagaaa agctacacat
    42601 aatacccatc ttagcatttg gatcgatttt ctttaataat tgagtagcac gggcgttcgc
    42661 tagaaacata tgatgacagg cttgataaat cacttttttt gttagtgtag caatgggttc
    42721 aagtttatct ctagcaggga atgtaaccaa tccagcagct gcataaggca tacgaaaagc
    42781 attattgatc tcattaaagg tcatccaata tttcactttc ccttggtagc gttcaaagac
    42841 ggtctgcgca taaaattcaa aaaagtcgat taattttcga ttttgccacc ccccatactc
    42901 tcctaccaat gctaaggggg tttcataatg actaagagta attactggct cgatatcata
    42961 tcgatttaat gtattgatta gtctgtcata aaatacgaga ccagcctcat ttggcttctg
    43021 ttcgtctcct cttggaaata ttcgtgccca tgagatgctt gttcgaaaag cttttaaacc
    43081 taactccttc agtaaacgaa tatcctcttc aaatcgatga taaaaatcaa tcgcttcatg
    43141 agaaagataa tggagtgatt cgtctaaagc aatctcccaa atcttttttt cttcattcca
    43201 ctgaatacta ggatgctggt tcatgatccc gataagcgta tctgtcacat taggtaattt
    43261 gccgtcttcc aaccatgcac cttcacattg attagcagct actgctccgc cccataaaaa
    43321 attttctgga aatatttcct gatccataac tatctctcct cgctatcaac aatttcttac
    43381 ttgaagtata gctcgattca tcaaaacaag atattctaac tatttcggca gaagagaaga
    43441 aaaaaattga atgctactct tcatttttaa tatttatata taacaaatac ataagacgat
    43501 ccccgaaaga aaacactcgt taaccatcta agcaaacgat ttattttact tccaacacaa
    43561 atgcttcata aggtcgtaaa tcaactttgc cgtctggtaa ctgtttcaga ggataatttg
    43621 acacaataac ccttaaagct tcacgtggaa tagtgaacgt ctgcttttca ctggacatat
    43681 tacaaataac gagccattgc tggtcttcat atatgcgaga ataggcaaag acatgctcag
    43741 gcgtcttttc cactaattca tagtctcccc agacgatgat gtcatgtttt ctacgcaaat
    43801 cgatcaattt cttgtacata taaaaaacag aatcttgatc tgctaacgct tcttctgcat
    43861 tgatttcttt ataatttgga ttgactcgaa gccatggaat tccagtagta aacccagcat
    43921 gttcacgggc gttccattgc ataggcgtcc tagcattgtc tcttcctttc gccttgattg
    43981 attccaagat ttcctctttt gtaaatccag aagaaatcct ttcgttatac atattgattg
    44041 tctcaatatc ttttgcttcc gcgatatcat cgattgggca attcgtcatg cctaactctt
    44101 ctccttgata gatataaggg gtgcctttca tcatatggag caagatagca aacatcttgg
    44161 cactttcttt tcgatacaca tcgtcatttc cccaacgaga aacaattcgc ggaagatcgt
    44221 gattattcca aaataaacta ttccatcctt catcacctaa agatgtttgc catttggata
    44281 atactttttt cagttcagag atactcaagg gtttcaaatc ccatttgtct ttgccttctt
    44341 gctgatctaa tcctatgtgt tcgaattgga agaccatgga taattcattt cttttaggat
    44401 tggaataaag tttagcgatt tcggtagttg ctccccatgt ttcgccaaca gtcatcagat
    44461 ttttgtcacc aaaagttgct tgattcattt cctgaagata ctcatgcagt ttaggtccat
    44521 tacttgtgat ttctttatcc ggttctttgc caatcatatc gatcacgtcc atacgaaagc
    44581 ccccaatacc tttatcgatc cagaaattca tcatttgata aatctcttgg cgaacctgtt
    44641 tatttttcca attcaaatca ggttgacgct tgctatacaa gtgcagaaaa tattgccccg
    44701 ttttttcatc caactgccaa gcagaaccac tgaatattga gcgcaatcta ttaggctctt
    44761 ttccattgac cggatcacgc caaatataat agtcccgata aggattttct ttatttttac
    44821 gggcctcaat gaaccacgga tgttcatcag aagtatgatt caccaccaga tccatgatga
    44881 tacggatatt tcttttcttt gcttcttcaa tcagttcttc catttcttcc atcgtaccga
    44941 attctgccat gattgcttga taattactga tatcataccc attgtcatca ttcggagact
    45001 cgtatactgg agaaagccaa attgcatcaa tacctaaata cgccagataa tccaacctgg
    45061 aaataatccc ccgcaaatct ccaataccat cttgatttga atcttgaaaa cttcttggat
    45121 agatttgata aacaactgaa tggtgccacc atttttgttc catgattttc ctcctataaa
    45181 tggatgtttc tattttttgc ttaatcattt attttagtct ctctcactaa aaattgtaac
    45241 gctttcaaat agctattgca ccttgttatc ggtaacagaa taaaacaaaa aaacagctga
    45301 ggaaattccc tcaactgttt tttgaaagga ttgatttatg cagggaagaa tgctgatttc
    45361 acaacttctt tataaacggt gttcactcag ctgtcccttg gtattagctc aaaaaacggc
    45421 aaaatataag aaactatttt ttcgtttttt tctctaatac tcaggccaga acgctgattt
    45481 cacaacctct ttatttcaca ttcaatatcc acatgaatcc cacaaataca aagaacagac
    45541 catacatgat tggagatact tcttttcctc ttttagctgc taacatggta attggataga
    45601 agataaaacc taatgcaatc ccatctgaaa tactataagt caaaggcatg ccgatcaaga
    45661 tcaagaatga agggatcgca atctctaagt ttccccattc gatttgtcgc aaagattgtg
    45721 ccatcaatac tcctaccata atcaatgctg gtgcagttac ttgtgaagta acaactgata
    45781 gtaatggaga aaagaacaag cctaacaaga agaaaatccc tgtagtaata gctgtgatac
    45841 ctgaacgtcc tccaacggcg ataccagctg atgattctac aaatgcacca acaggagaag
    45901 taccaaataa ggaacccgca agcatagctg ttgaatcaga agctaaagct ttccctacac
    45961 gaggcatctt gttgtctttc atgaaacctg cttggtttgc taatccaact aaagttcctg
    46021 ctgtatcaaa gaaagtcaca agcaagaatg tcagcactac gacccacatt tgaagagaat
    46081 tgatgtcccc tacatgtttt aatgcaacta aaaatgttgg tttcaaactt ggtgctgcgg
    46141 caacaatttc agaaggcatt ggaatcaaac ctgtgaccag acctaaaatc gttgtagctg
    46201 ccatcccgat gaagatgcca cctggtacac gccgaacaag caagatagca gttacgacta
    46261 atccaaaaat cgtcaaccaa gtagaaccaa cgttgagtga tcctaatcct actaatgtag
    46321 attcattcga aacgatgatc ccaccttcgc tcagaccaag gaaagcgata aatagaccga
    46381 taccgccaga aatcgcatat ttcaaatctg ctgggatcgc atcaatgatc atttcccgca
    46441 gcttgaagat tgtgatcaaa ataaaaatca aagaagcaac gaatacgccg gctaatgctg
    46501 tttcccatgg aatccccatt cctaaacaaa cagaataagc aaaaaaagca ttgatcccaa
    46561 gagcaggtgc cgttccaatt ggataacggg ctaatacccc cattaaaaca cagccgatcg
    46621 cactggctaa tgcagtcgca gtaaacactg ctccttcatc cattccagaa gcacctaata
    46681 cagttggatt tacaaataag atataagcca ttgagataaa tgttgtaaat cctgccagta
    46741 cctcacgttt taccgtggtg ttcaattttt ctatttcgaa gtaggaaagt attttttcct
    46801 tcatcttcca tccccctaaa tccgaacatt ataaataaag tccgttaaaa tttcgattta
    46861 ttaataaaac aacgtgtttt atcatatact aaaacaaaac ataagtaaac aaaaaattcg
    46921 gattttaagc aaaatccgaa cgttccatct gattaaatcc ctttatctca aagttcatga
    46981 acattcactt tggattacaa gaatttcttt attgtgttaa taaagtttct tcattctagt
    47041 ctcaaaaatc aatagtgtga tttgatttta ccatttcgtt tctgttcttc tttgatgaat
    47101 tcttttgtat cgacaggatt cagattattt agtccgccaa aacctgtatc gaccattttt
    47161 ccccagcctt ttgtcttctt ttttcctgat ttgagattct ttgctcgaag cttctcacta
    47221 tgttttgctc gccgatactt caaataacct tctaatcttc ccattagatc cactgttttt
    47281 cctccttttt attcaatcag acgactcagc ttttcctata acaaaataat tgccttcagg
    47341 gtcagaaaaa ttgaaagtca agatgccatt gttatctgtg atttctcctg gttcttccat
    47401 gttctcgtag atagtttcaa attcatccgt aaaaaatact aaagaaggcg gtggtcctaa
    47461 tacctctggt gaaaacttct gcacaaatac ttttgggaat acgcctaatt ctaattcttt
    47521 tgagatgctg agtacaatac tcttaaattc ttctggcaat tcgattgttt cagaaatttc
    47581 tgcaccaatt ttttctacaa agaatcggca aatcatctct acgtcattga cataaagcat
    47641 cacacgtgtt ttttgtatca tcatttgacc cttctttcta tttgattttc tttcctgtct
    47701 ataaactgat tccattatat cacgaaagcg caaacacctt gtgtttgata ctattcaaga
    47761 aaaataaagc aatagtttct aggattgctt tcctccacaa acttttttta caaaaaaaaa
    47821 acggcaatga atgccgctct tcttatttcg attcttttat aattctgctt ctgattcatc
    47881 tttggttagt gtgtgtctaa cactagttac gccaaatgtt tgatcgattt tttccttcaa
    47941 cgcttcgatt gcctgtgcgc cacgtgccgc ttgttcagca ttgatggatt caatgaccag
    48001 caccgctgct tgtgtttctt ccgtcagcat cgttctttgg gcttcacgcc agttgagaca
    48061 gcgacagatc gctccttgtt catcatagta gatgatttct tccggaagtg ccggagcatc
    48121 ggaatctgca cctaaaggca ggaatgattc gccaccttgg gcttttccta aatgcagatt
    48181 tcctgcgatc ttttcgatat cttctccgcc gcaaggtacg ccaaaagaca aggaaatact
    48241 attatagata tctacaagcg gattgattgg gaaaaattcc cgttcttgat ttgcacgttt
    48301 cagtaaagct tcaatagaag aacgtgcacc ttttttagtc ttgaatgtgg taaatgcctg
    48361 acgccactga gcaatgactt cgttttggct gaatgtttct tctgtaaggt aatttcttgc
    48421 ttcttttgct gcctcattca ataattgatg atacgtttct tcactttctt ttgttacgtg
    48481 gttatcgata ccatttacgg ataagatttc gatggttgct tcaggaaata cttcccagaa
    48541 attggtatcc actattactt ttttcatctg ttcacacctc ttgattagaa taattgcttg
    48601 atgaatagat agtctgtttg gggatcatct cccatataaa aaacatgttc gctgtatttg
    48661 ataaatcctt ttttacgata aaaagcgagc gcaacatcgt tgtgttccca aacaccgagc
    48721 caaatggctg ttttttgctt ttcttttgct ttttcaatag ctgtatctag taaaaatgta
    48781 ccgatacctt gatgtttaaa tttttttcgt acatagattc gctcgatttc taaaaaatga
    48841 tcagccattt cctcagattg actcgttcct gtatttagtt tcaggtaacc cgcaggctct
    48901 tgatcgatac tcactaggaa aaaatcggtt tctttatctt ttagctcttc tgtaagtttt
    48961 tctagtgcat aagcttgtgt caagtaatca gctaaatgct ccggtgaatt atcttttcca
    49021 aatgtatctg taaatgtttc gatactaatt tgttgtagta agtctacatc tgaaggcgtc
    49081 atttttcgaa tttcgtattt attcacggct tcttcctttc aatagatcct tttattgcct
    49141 tttttgacaa aattccaatc ttcgctaaca ttcttgcata ctttatttaa aagatattcc
    49201 aattgttttg cttcttcgtc agaaagacca tttaatgcga ctgcattgga gtagttgttt
    49261 tctcgaatga tgaaaggata gatttctgct ccttttttag tcggatagag tttcttgatt
    49321 tttttatttt ctttatcttc caaacgttcg atcatcccat tggattctaa tttcttgatt
    49381 gctcgggcag tcgttgtacg atctactttg atcatttctg ctagtttttc ttggatgatt
    49441 ccaggatttt cgcaaatacg tactaaataa agatactgtc ctcttgttaa atcgacttct
    49501 ttgaattcga tattgctaat agaatctagc gctcgggcaa tcattccgat gtctcgaagg
    49561 atttcagcca tttcatccca cctttatttt gtttgtaaga ctagttcacc tctttttgtt
    49621 gcaaatgcaa ctattttcaa taaaaaaatc aagttctttt ttaataacta gtaaagtata
    49681 ttcttttctt cttttacgaa aaagctcaat cacaatagat ctggtttttg ttttctaaaa
    49741 taagtaactg tttcttcgtt gttcgctttt ctgatagctt tggcaactct tctatactaa
    49801 aaaatcccat gttggaagtt tcattattct caataaactt ggcctcttca ccgtggatcg
    49861 cacaagcaaa aacaagttta taatactgaa aaagctgtgg aatatctttt tgtttattcg
    49921 tatcaaaaac tgctcgcaac tgagtagttt ctactgttaa tcctgtttct tcatagactt
    49981 ctttacgcac attttcttca ggagacaatc ctatttcagc aaatccacca ggaagtgacc
    50041 attctttcgt ccgtttatct tcgattagta ggaccttgcc atcttttttg atataggcac
    50101 gaacatctac ttttggtgtt ggatgtcctt ctccaatcgt tgtgagcgct tttatttctt
    50161 cgaaagtttc ttttcctatt tcactgatca gttccaatga aatcgtccgg atctcctcaa
    50221 aacgctcttt atcaaataca tcttttccat aatatagacc agcttgagaa agtgcgagta
    50281 gtcttttgta ttgagccaac ttcttgttca ttctcttccc ttctttttta gcaaatgtat
    50341 gactatgtaa tcaagtatag aagactggtt taattacggc aaataaatat aatgaaatct
    50401 gcaataaata aaagaatgtt aaaaaactcg agaacaaaag acattcgact tctctggggc
    50461 tgtgaataaa tggcgttcaa aagcttgcat ctgcggtaat aagccccacc aaacgaaaaa
    50521 tatgacgagc tattcttgtc tggctgttct tattaattga ggcaggacag ctttttcaca
    50581 acctccccac taaacggtgt tctcctacca actcctcggt cacaagtcac aatattcatc
    50641 aaacatgaga agctgttttt ttgaaattgc tccttgtgac tcggagctga acgacaggct
    50701 cacgacctct cggtaaacag cgttcaaaag ccaatttttc gatattaagc catttctttg
    50761 ttacttattg tcattgattt ctttttctaa tttatccaat agtggagtgt aatccacttg
    50821 agtatagtct gttacatcaa attcatatag tgttcctaac tggaatttgt catattttcg
    50881 gtcggcgatg atctttttga atgcttcttt cgtaatatga ttggtccctt tcgttcgatc
    50941 ttccaatacg tcaccatagt gataatgatc catgatatag ctcaaatgac gatctgattc
    51001 acgatcacgt ttgtaccgac gttgccataa cacttcaaag tctgctgtta ggcgaatcgt
    51061 gatcacctga tatccgtatc tatctgctaa ttcttggagt cgtgcttttt gcttatcact
    51121 aaaaggatac tcggacacaa tcactttctt tcctgcttcc atatacaaat caagtgcttt
    51181 gtaatagaaa ggataaactt tcgtcctttc ttgttccgcc cgttcttcca aattgttaaa
    51241 cccgatggat tctgcatagt attccttgat ttcatcgagc gtgatggcat acatatctgg
    51301 aaatcgttcc cgtagtttat tcataagata tgtttttcct gtaccaggac taccagccag
    51361 aagaatgaaa tactttttca tctcatttat ttcctaagtt aattggactt tccaagttca
    51421 taaacagtcc aatcttatgc ttgacaattt cttttactgc ttcatttgct ggaatcacat
    51481 tatggcgaag agacttgttg atttctgttt cactaaaggt ttctttagct actttcgtcc
    51541 agttgactaa aagctccgtt ccaacattga atttgcggat cccgttattg atcaattcag
    51601 gataatcttc ttctttcaca cctgttcctc catggataac tagggggaca tcaactactg
    51661 catcgatttc tttcagcaag ggaatgttta cttctgtttt tgatttgaat tgtccatgat
    51721 tcgtaccgat agcaatagct aatgcatcca cgcctgtagc ttctacaaat ttcactgcgt
    51781 cttccggtct tgtatatacc ttgtcatttt cagcgacatg gattccttct tctgtaccgc
    51841 cgattgttcc aagttctcct tctacggaaa caccgtgcgc atgggcatat tctactactg
    51901 cttttgtctt caggatattt tctttgaaag gcagatggga cccatcatac atgacagaag
    51961 tatatccgct gtcgattgct tctttgatat catcaaagtc tcgggcgtgg tctaagtgca
    52021 agactgcatc aaccatttct tcttctgcaa tagctgtcat tacattgact aacacatgca
    52081 tgccgatata tttagcggta tcgacacttg tttgaataat gatcggcgaa cccatttctt
    52141 ttgctgcgcc tagcatagca ggaagcattt ctaggttatg cgtattaaaa gctccaactg
    52201 taaaattcaa ctcttctgct gtttttgtta cttctttcaa tgttgtatac atcttttatt
    52261 gccaccttat ctttttattt gtttcctttg atcgttactt gttttgcaat ttgtcgcatc
    52321 tcatccattt tgcccatgta gtaatcgatc ccttgatcat caccagcacg agcagcatct
    52381 gcacgcttct ggttatagag gctcatcagt tttttatacc catctccgat cgtctgttta
    52441 ttttccaaac tcttttctaa atattggatg gcttgatcgt tcacatacaa ttcagaaaat
    52501 ttaagtccaa cttgttcata aagtttcgct aatttatgct tatcttgggt agtggaaatc
    52561 tcttgtttca attgtgtaat ctctgattga atcttttcgg tcgcttctgg cgatagggct
    52621 ttttcttctt ttgccagaac ttttttcggt tctttttctt ttttcttaaa aaatccaaac
    52681 atcattttcc ctactttcaa ttaaaatgct ttcaaaactg ggcttaagat ccaggcatat
    52741 aagagtgctg cggctactgt atctacatcg gttgctgtag cattgttgaa tcccatcgaa
    52801 ttaaagatcg ttactagcaa agcgggcaat aatgtaataa agaaaccatg agcaataccg
    52861 ccaatgatcg ctcctcggcg tccgccaact gcgttgccaa atatccctgc tgtccctccg
    52921 gcaaagaaat tggttagcat accaggtaaa atcatcgcta agccgaacat gggcaaagta
    52981 aacatggcaa taatcgtacc aatcgttgtc gtaatgaaac ctaaaatgac agcatttggg
    53041 ctataaggaa agaaaactgg acaatctaag gcagggatcg catcaggaac taatttcata
    53101 gctatccctc gaaatgccgg cacgatttca cctaacagta gacgtacacc agctagcaat
    53161 acatacacac ccactacgaa ttggatggct tgtaaaaagg caaacatgat atagttttga
    53221 tctcctgata attcagaagc gaatggttcg cctgcaaata aaacagtgat gatatatagc
    53281 gggaccatca cgaccatgac agacaaataa gtatcttgca gaaattcgaa atgtgtcggc
    53341 aacttgatat cttcgatcga ctttttattt tcgcctttct caccaaaaag cttagcaaca
    53401 ccggcttcaa ataagtaccc gatcgtacaa aaatgaccta aagcaatatc atttgatcca
    53461 gtgattttac gaatgatcgg ttgcgctact gccggcatag caatggcgaa acaagctccg
    53521 ataaaaccac cgaccaagat caatacgatc cctcgcagac cggcaaaata gccaaagact
    53581 gtcgtcatcg ttgccatcca taaaattgct tgaccagtta aaaaaatgta cttccatttt
    53641 gtgaaacgag ccaaaataat attgaataca aaaatggcta agaacgtcag tgcaatatct
    53701 ctacctaaac ccaaatcatt cattgcttga ccattgatag attcaataga agggatgatc
    53761 ccttgcatat gaaatccttc agtaaagatt ttcccgaaat aagttaaact tccaacgatg
    53821 atgctcgaac cggcactcaa cacttgaaat cctaggagtg tctttaacgt gccagagatg
    53881 acttgtcctg ctgatttctt ctgcagtagt agacccaaca tagcaatcaa tgcaatggtg
    53941 atcgatgcct gagtcaaaat attttcgatg ataaaattga taacgcccat gtttttaccc
    54001 tcttttcttt ttgtatttag ataactccct tatcttgcag aactggggtg attttttctt
    54061 caatttcatt ttttgaaaca atatttttca aatagatcat cgccgtttta ggatcaactg
    54121 cgaacttttc gaactgcgaa cgaaaatttt ctgctgtgat gatcacatct ggtttcatgg
    54181 aaactgcgga agaaatatca caatggtcca gtttggcttc tactcctaat ttgttcaaaa
    54241 catcctcagc agacatctgt gctgcaaaac tacttcctaa acctgcaccg catacgaata
    54301 aaatgttcaa tttgttcatc tttgttctcc cccgtatcat ttattatttc tcaactactg
    54361 aaaaaagcag ttgtttgaaa tcttcgatat ttgtgcattc aatcaatcga tccaacttct
    54421 cttcgttgtt gatcaattca attagttctt tcatgatgtt cagatgcgag taggagtcta
    54481 ctgctgccaa acaaaaaata atctttactg gatccatttc aggattaccg aaatcgattg
    54541 gttgctcaat cgtagctacg ctgactccta atttattgac cccatcttct ggtcgggcat
    54601 gggctagtgc catgtgtttg ccaatcacga tatacggtcc gtaatcattc actgcacgaa
    54661 tcatcgcttc gacatagcgc tcttcgacaa tgttttcttt aaccaatggt ctagcagcta
    54721 gttcaatcga ttcctcccaa gtagtggctt tttctttgat catgatattg ctgtccgtca
    54781 aaatatcttt taacataggc tggatctccc ttttgttgat ttctaaattg tttgtttcga
    54841 ataatttttc taacttgcca tagatgattc gatctactcg gccaccactt tctttcatga
    54901 catctattat ttgagtgaat aactccgtcg attcatgact gttaggctct aaccgctgta
    54961 gttcttcatt tcttttcaaa aagtcttcta taaccaagat attcgtctca gttaaaatcg
    55021 gatcgacaac taaaagcggc ttatttcgat aattcaattg aaaggtgctg aaaaccagat
    55081 tgacatccaa tttatctact aattcgattt cttttgaact taaaactgca gtaatctcga
    55141 tctgaggaaa cttttctttc agattctctg ctaacagatt tccagtagcc atcccatggt
    55201 tacagacaac gactgattta taaacataat tcaagtctcg cttgattaca ctggcgatcg
    55261 tcgaaaagtg gatgacaaga aaagctatct cgtcctccag tatcttgcca ccaattactt
    55321 cttcgatcgt aggaacaaaa tgagtgactg cgcggtagat tgggaaataa tttgttcgga
    55381 tgttttcttt caatggattc atgacttgga tatgattctt gattcttaca atcagtgcag
    55441 ccatgtgctt atagagattt tcgaataaag cttcttcctt tagatggaaa ggtacgtgtg
    55501 tctcgttctc tacaaattgg atcaattgga tcgttagtaa ttgagcttgt acccactcga
    55561 ttgaattgga gatatctcta gcattgaacg tctcaatagt gaaacgaaga taatttcttt
    55621 ctacttgcgg gacattgtcc aattgaaatt cctcgatcat gtggtcaata aatgcagaaa
    55681 agctactgtc ttttatttct gtatttttcc aattaatggc agagataaat tcatgtttcc
    55741 tgattcgctg gatccagatc aatgtaaaaa gcaggatttg ttttttataa atatcatctt
    55801 cttgtttcaa caacttattg gaatagatct cctgtatttt tttgatttcc accaaaggaa
    55861 aataatggag aaagattttt tgagccggtg ttaattgtgc atcttgattc ataaagaagt
    55921 cggtcattcc cagattctga ttgataaaat catagatcat cgtacggata gatcgttctg
    55981 aacctttata aaccagtcct tgctttccat aactgacgat ctctatccca taactgacca
    56041 gtgttgctcg taaccgtctc atatcttcat ctaatgtact tttagagatt tgaaattctt
    56101 cttctttttt gtttagatgg atcgggattc ggctgtaagc aacggctaaa actagatcaa
    56161 aaatacgttc gcgccgattc aaaaagccgt ctttcacatc ttttatttca gtttctaatc
    56221 gagcttgctt ttccttttcc agcttcaaca aaaaaccttt gttgcgaatt gtacggatct
    56281 ccggaagctt tttactgctc aaccagatat tcgcttcaag aacttcctga cggatcgtcc
    56341 gctgactgac attgaactca cttgctagat gttttgcttt tactggatat tgggctgtca
    56401 tgattctgtg aagtatttca attgttcttg ttttcataga aatgatctcc ttctgatttc
    56461 aagtatatgg ttccgcttac ataataaaaa gtagatattt ctgccacttg aagtggaaag
    56521 aaagtaagca aagcaaacaa aaaataagcc atatgctttt tcatctcctc aacgaaaaag
    56581 acatacgcct attattacaa aaattttgcc catctataca aaaaagaggt tgtgaaaaag
    56641 ctgtcctgca tcaagtaata agaacaacta aactaaaata gtgcttccta tttttcgttt
    56701 ggttgttctt attatcgcag atgcaagctt ttaaacacca tttagtggag aggttgtgac
    56761 agagatgttc agccttgagc gataagaagc gattttgaaa aatcgcttcc catattttac
    56821 aaaatcgtgc cttattgccg ataggctatc tctggcacac cgtttattca gaaaaaggag
    56881 ctgcgacaag gcttttgtca caactccgtt cataaatatt tcctgtcaat ccagcataat
    56941 tggctgaata aaatcggctt gccatctttt ttctttctca gaaaaatcaa aataccatat
    57001 ctgagaaaaa tactgtcgtt gtgtcttact tcctgagatc aatcgcccat cttttcgatc
    57061 gactgaataa tcacagcatc tgaaatcaat tcggatggca aaactatttt cgtggatctg
    57121 tcgataattt cctacttcct gaatagttat ttttttagta tgatttctta caccgtctgc
    57181 tttgtttttt tgcagaactt tctgatgttc ggcaaacagc ttgtctgtat aacagcttct
    57241 ggctttttca ggagtttctt cttcccaagc ggattggatc ttcatgaata tcttttggat
    57301 ttccagaaac tgtgctttct tttctttagc cgttcctgac atgcgggaca atatctccgc
    57361 tttcagcctt ttcttttgtc ttttattctt gacgatagaa aaagcagaaa cccctcctac
    57421 tgacaaaaca gctaatgcaa gaaatcccgt ttgctcataa ctagaaggac ctgtacctgg
    57481 accataatac ccataagaat ctctgccgta agaacgactg ccaaaataac tgcccccata
    57541 tgaacgacca ccaaatgaac ctctgcccga acttcgaccg ctagatgtac ctccaccatg
    57601 accacccgcg acagcgaatc cttgggtcgg cagagcaaac aaacataggc ccactaacaa
    57661 aatgattgct aaataattga tttttttcat tgtcttcctc gttatctttt attacaaaaa
    57721 actattttta tgatagcctt gctaaaagga agagtcaata accagatgca taaactgttt
    57781 ttttagcaat tttgtcttat ttagtcattg agtaacatcg gacaaatgta tgtgtcggca
    57841 gtccataatt cctctatctt cagcatgaac aagcttgcag acaagagatc tgcgcttcct
    57901 ccaggagaga tttggttttc ctgacaaaag tgcaacagtg ctgtaaatgg acgatttggt
    57961 aaagcacttt gactagcagc atgagcaagt ttttgcattt ccactaacgt tttctgatca
    58021 ctgcgatgca atacgcatgt gtcatctagc gaactcatca aaactaacaa catatgcatt
    58081 tgtttctgta catatgaatc attatctagc tccttagctg cttgaattgc aagcctgata
    58141 tgcggatacc ctaatatcgc ttcttcatat gcaccattta cgccatattt ttgcttcacc
    58201 ctatgaccat gagtggtttt tttatgacga tattttgtat caggaaaagc agcaagcttg
    58261 ctgacatcat caagtatttt cgataaagaa aaaggctgtt ccatactgat tttttgtgca
    58321 atgacactga tcaatagccc cattgcccaa atcgctcctt tatgggtatt gatgccattt
    58381 gtagcaatca gcattgcctt ttccgctttt cgcccaatct cagcaattct ttctcttaac
    58441 tcctgatcaa tagcatgatg ccatgctatt tgagccattt cttcaaaaaa aggagttagc
    58501 gtcttagcag acttaagaaa taaagcatag tccatatcgg aatgtgcacc cgcatccagt
    58561 gcatccacta atccaggttt tggacttaat gttacttctg cgatcaatgc ttcctctacc
    58621 aacgcagcga gttgctgagt cactgctttt tttcgttcgt catttatcat gacactcact
    58681 ccttcttcct actattactt gctgaaacct tttttgatag ctacccaaat gatatgaagt
    58741 aaccagctta aagcaaatgc acaacttgcc gtcattagat aagctacaag aatcatgact
    58801 cctgaaggta actgcagcca actatcttta aacaataata acagtacttg gaaaacaaat
    58861 acattggcta aatacgtacg ataagcataa acagacaacc atttgaacaa tggcaatttt
    58921 ggcgaatcgt ttacaatcat tttggaagcg cctatgaaga cagcaaagat gatgactaaa
    58981 ctgtataaac tttggatcgt attcaagtaa ggtgcattcg caaagctcaa gtctcctgga
    59041 tgtgcgagca atgaacggac agaaaagaac gcgataacta aggcaacagg taagaaaaga
    59101 taacgtactc tgtccaaata ttgatagact ttttcgtgat aaacaaatgc ggctacccca
    59161 taaatcatga aactagcaac aaaccgatct aataagtacc agctgtcatg ataaggccca
    59221 gtcaatactt gtgtttgata gaacagatac catgcgacat ataaaatcgt tgaaccaatc
    59281 aatactggcc atacatattt tttattagca aatactttgt aaccgagcca aacaaaaaac
    59341 ggcatgaaca attggatctg cagcatcata acggtatacc ataaatgagg cgctccatca
    59401 cctgtgacat atttcagtaa aaagcttgca gtatccgtat acggagtttg ttgttggact
    59461 gctggaaata gccaaagata agccgtcgtc catagaagat acggaacgac tagttcaaaa
    59521 aacttttctt tcaaaaattc ccaataagac aaatgctgac ttgtttttac catattataa
    59581 acaattgcaa aaataaacat tggtgctgtg tatttaacga tgacgtaaaa ggtaccaaga
    59641 aaagctgtat ttgttgcgct gtggctgttt gccaaagcaa agctcaatat cgtttgcatc
    59701 ataacagccg ttacagctga tactttctgg aagtcactta cgttgatttt gatttttttg
    59761 ttttcaaaca tctctttctc tctctttttc tttattacca aagttctttg gttaatttag
    59821 gtccttcgac tgttttcaat agaatttttt tctctggctc tctcaaatac tcttttagtg
    59881 aaaaaccgcc ttgccgagtc actacttggg tatcgaattg ctcaaaaaaa gcaggatgcg
    59941 attgaattac ctgaattggc aattcaatcg gtgaatttgc gtacagcagc aaatcaaaat
    60001 cactggtttc ttttactgcc ggaatcccag tcgataattc aaatcctaag ctgccgccga
    60061 ttccccattt acatcctgat aatatgtttc tagcagcatg aaattgctga taaacaggat
    60121 aatccatgat tttctcttgt ctatacgatt cttgttcgat gatgtcccac ggatgaatga
    60181 cttgtttgac ggcatgtttt gagatttctg ttgaccatct ctgattgcgg gcaggtccac
    60241 gtaaaccaat cggtagtatt tctgcgtgat ccgtcgacgc acgacgaact gttccgaaca
    60301 tcttttcagt tagaacgacc cattcaggca aggtgaaccc ttctatttca tgtttatcaa
    60361 aaaggacaat atcatgtgct tgaatcattt tttatgcatc ccattcttcg tccattttgg
    60421 cacggacttt atttgtttcg acacgtccga atgttttggc tgtttcgttt gtgtatcgat
    60481 ttgtcagcat cgtgtcattt gtattgcgga catcttgaat ggcttcattg attgcttcga
    60541 tgactttgct gacattttgt tctgaagcag cttggtcggt gatatcttct aggaaatgat
    60601 agatcgctcc tagttttgta taattattga tatcgtaagc gatagctgga actttttcag
    60661 cagctgcttc gatttcagca accgaacgtt ttgtcacacg tgcagcactt tctttagaca
    60721 tcgcttggac ggtaatttct ttattgttta aagcaatcaa gcggcttgat tgtaatccat
    60781 gtgctaaaaa tgcacctgaa atagcatttc ctgcaatcaa tccaataact ggatgtccag
    60841 cttgacggag ttttgcataa gcagcagcac tattagccaa agccacatgg ataccgatca
    60901 attcttcgtt atagccgtat gcttggcttg gtacatcgat cacaacgatg attggccgtt
    60961 tcactttttt gtctttatct tcttcgtaaa cgtgatccaa aatttgtccc atgcggaaac
    61021 cttcaactaa accaacttca ccgtttcgta cacggtacat cgggttttta ggatcaggta
    61081 cgattgatgt cacgatggct tcttctatga atttacttga tttaccataa tacacagtac
    61141 taatagaaga agttggattt ttcatgccag ttagtgccgc aaaccaatcg taaccaacac
    61201 ttgctgcagc tggttcattt ccttctgcta cttctggtaa gtcaattgat tttgcttgat
    61261 ggttagcaat tgcttcattg taatcgtcaa tggccattgg ttttgaaaga tctaaagaat
    61321 caagtaatga taaataaaat gctgagcttt cactgcgatg cgtgtctttt cgttcgtcca
    61381 ttgctgcgat gacagcagct ttgattgctt ctacactatc agtcactaat tcatcaatga
    61441 tttttgattc tacccgttga cgagatccta atgtattcca aatcaagtct ttgtcactag
    61501 aatcaaattc tcgaacgcct gcttcttgtt caataacttc tggtccattc aaaccgactc
    61561 tcgctttttt tgttgcgatt aaataactca ttaatgctga agtaatcgac ataccgccaa
    61621 atgatcctac acgtcctgga atcaaaccga tgactggtac atattgtttt agagcaatga
    61681 ttacatttcc gatttctgaa atagataaca gtccgtagtt tgcttcttgc aaacgaacac
    61741 cacctgtatc tagtacaatg actggaaaga tctcatttcc ttttttattt tcttctaaca
    61801 catgttcaag tgcagcaacg atttttgcac cggaaacttc accgataccg ccaccttgga
    61861 attttccttc catagcgatt actactgctt gtttgccatt gatcgtgcca cggctgacaa
    61921 cgatcccgtc atcactttca gggacgattc cttgtgctgg taaacttggc gcgatgattt
    61981 gatcgaatgg atcaatcaat tcacgtccat tgtcaagtag agcgttcact cgttctctgg
    62041 cgtttaattc tacaaaacta tttttcatct gaaagttcct ccattgcttg cgtcaatcgt
    62101 aggtacacaa ctcctggtgt agcaccgaag tcattgatca cgatatctgc tgaaattgga
    62161 taacgatcaa aaaatctcgt taatacattg ttccatactt cgccgaagcc atcgcttcct
    62221 gtacaaattt ttacagtaga ttctgttttt tctgttggaa acatcaagat ttccaaatct
    62281 cctgaaccga ccactcctac atggattttc ttattgatcg gctgtttcgt tggatattta
    62341 taagctaatt gttccatgga tctctcccct ttttgtaaaa cagagcatac acgttctgct
    62401 tattcgtctt tcttcttcca tctgggtaaa tggcgacaaa aggtttttct cgccaatttt
    62461 atgaccaagt tctgaatttc attggtggtt catacaggcc atctgaccat tcgatcaaat
    62521 catcgatggt ttgtgcagct aataatgaac gtttcgcttc actacgtttg atgcctagat
    62581 cttctggtaa tttcacgatg ccggctgcac gcaagctatc tagtgattct ttcgtgctag
    62641 tcattccaag aggtgtaaca ccgccaattg ctgcaattgc tgcttgtcgt tcttcttttg
    62701 tttttgcttt gtacaaataa gcaattcctt cttctgtcac gatatgtgta gtatcttcgc
    62761 tataaatcat cactggtgca ttggctaagc ctgcttgttt ttgaacagct agtgcatcta
    62821 attcttcgac aaagactggt tttttatttg aaccatatgt ttcaaccatt tgaacaacta
    62881 atttttggcc tttccctaat ggatcatcat tgtcgcgaag tgattgccat gctggtgtag
    62941 aatgacgacg accgccagga ttatgtccca tgttaggcgc accgccaaaa ccagataaac
    63001 gtccttttgt tacggtagaa gagtttcctt cgtaatctaa ttgcaaggtt gaaccgataa
    63061 acatatcgat ggcatattgt cctgcagctt gtgataatgt tcggttactg cgcatcgtgc
    63121 cgtctttacc gacaaaaaag acatctgggc gagcagcaat atatttttcc ataccaactt
    63181 cgccaccaaa actatggatg ctttcaaccc aacctgattc gatggctgga atcatcgttg
    63241 gatgtgggtt caatacccag ttcttcgcga ttttcccttt taaccctagt gattcaccat
    63301 aagttggcag taacaattcg atagctgctg tattgaatcc aataccgtga ttcaaagatt
    63361 gtacgccgtg ttctgcgtag attcctttga ttgccatcat tgccattaga atttgcaatt
    63421 ctgtgatgtt ttgaggatct cgtgtgaata aagcttctaa ttgataaggt ttatctgctt
    63481 tcacgacaac gtctacccag tcaccaggga tatctacacg tggtaaagaa tcgacaactt
    63541 cgttaacttg aacgatcacg ataccatctt tgaaagctgc agcttcgatg attgttggtg
    63601 tttcttccgt attgaaacct gtgtacaagt tgccgtcttt atctgcttta tctgcagcta
    63661 ctaaaacaac atttggaatc aaatcgatga ataagcgtcc ataaagttcc aaataagtat
    63721 ggatatcacc taatttcatt gtgccgtctt caatcatttg ggcgacacgc aagctttgtg
    63781 caccagcata agagaaatcg atcttgcttg cgattccttt ttcaaaaata ttcaaatgtt
    63841 ctggtcgtga gatactagac atgatcaaat gcagatcatt cactttttct gcatctactt
    63901 tttcaagact ttctgaaaga aaacttgctt gtttttgatt gtcgccttct aatacaactt
    63961 tgtcgccggg agcaatcagt ttttccatta cttctacgat tttttcagtt tctacatact
    64021 tgccattgag caagttgctg attttttcca atcgctgcgc ttttttttcg cgtttagaag
    64081 cccagttgcg gtttggtttt tccataatta gtcatctcca tttttgatat agaaacgtgg
    64141 cgtcatcaat accatgttgg tctagattga tcgtacggat ccctttatct acaccaaatt
    64201 ttgtatgaat cagctttgtc aaagtattgc cggggggaaa ttcaatcgtc agatccattc
    64261 ctaattcttt tgccaagtcc atcatttggt tccactgcac agggaaagct aggttttcca
    64321 acaaatcttt acgaatctct tctgcgtcct gagtggctct tccatccgta ttttttatat
    64381 acaaacatct agcatcagat agatggacag actgcatata cggcttgaat ttcttgaccg
    64441 tatcattcat caagagacag tgagatggca cagggacttt cagcagcttc gctgtttgcg
    64501 cttggtgccg tttggcttct gccaacgtaa cggataaacc ttcgatactc ccagataacg
    64561 tatgttgcat cggacaattt tcatttgaca gataaactgg atggtcagga tcaaatgttt
    64621 ttgctacaat ttcctcagct tcgcttctcg tcacacctac tactacgccc attgcataac
    64681 cgcttggata agcttctttc attaagactg cgcggtgata gactagttcc gctgcattct
    64741 caaatctcaa agatcgacaa gcaacagctg cacaaaaagc accaatcgaa tgtcctgctg
    64801 caatatcagg ctgaataccg tttttttcca tttcatctaa ataaaatact gcttttgtca
    64861 gtaatgctag ctggataaaa accgtatctt gatagttttc ttctttatca actaaccgat
    64921 accccgtcac attttctaaa cgttccatgt acatttcagg gatatccgct aacatcccta
    64981 acttctgact gccttgtcca ggaaataaga aacctgtact catgagcctc gcctcctcag
    65041 cacttacttt ttccactgct atcttagtca atttctgcta taataaaaaa tgccaaaaaa
    65101 agaaaaaacc ataacaaaaa ggtatggatg ggatggataa ttatgaaatt gcttcatctg
    65161 cagtatttta aaaaagtatt cgaaacaaaa aatgttaccc aagcagccaa agaattattt
    65221 atttctcaac ctgccttgag ccgtgcgatc aaacatttgg aaaacgaatt aggtgtccct
    65281 ttgttttacc atagcggcag aaacattgag acgaccgttt atgcagaaga attttatcca
    65341 tatgcagtca agacattaga cacattagaa gaaggaatca aattattgtc ttcggtcaat
    65401 gagaagatcg ttacttccgt catattgtat ttagaggtag cctctgtttc tattccgaac
    65461 ttggtccgaa tttttatgga aaagcatcct gatatccaat taacgatcat gcaacatcat
    65521 ttaccagatg atattaccga tcctgtactg tacatcactt cggagatgaa gcctggcatg
    65581 accaatattc ctatcatgaa agaacctgtt tatgtcgcca ttcctaagaa acatcctctt
    65641 gctaaaaaag aacatctgca attagaagat atccaacgca cccccatctt gatgctgtca
    65701 aagagcaacg ccttccgtca tacactggat gcagcacttg aagcgaaaag tatcgaattg
    65761 acgatcagtt cgacgacaga tgatcctgcg acattacgtt ctattgtcaa gcaaggatta
    65821 gctgttagct ttttcccaaa agtttcttgg tcttacgata aaaatgatcc tttcgtcttg
    65881 cgggaaatca aagatttgcc cttgacacga acaatttatt tatcttctag cttcacagaa
    65941 gatcatcctt tgatcaaaat gattgcaaaa acgatgcggg aattttattt aggaaaataa
    66001 aaaaaaaaga gctgggacaa aattcttgtc gcagctcttt tttcgaacaa acggtgttcc
    66061 agaagtaatt tcttagaaaa taagccgaaa tttcccaaaa atttgagaag caattttcgt
    66121 aaattccttc ttatttcttg aagctaaaca tttctgtcac aacctcttct ctattgtcct
    66181 agacattcat tgcgttgatt taaaacttcc atcaatcaaa tctgctagtt catctagctt
    66241 ttctatttta cgtagatcaa tagagatcca atgttcttta ttcatgtgat aggctggaaa
    66301 atacccctct tttcctcgca aaattccgcc aagttcagga tcgaccttca aatcaagaat
    66361 attgatgatc ctatggtcac ttgcatcatc atagattttt tcttctggaa cagacatcag
    66421 gaccccaaac cattttttgc ttttttgatg tctgaatacg caataatcag gaaatttttt
    66481 aaaaatatat tctggagaca aattgtatgt ttcattgatg tgatcgatta gttctttttt
    66541 cgttagcatc tgcttccatc tctttcttat tgattcgctt tattcaaaga taccacgtaa
    66601 gaatagaaaa atgaatacaa gtagttgcta atcaaatact tcgatatttt tcttttttat
    66661 caactcttaa atgttcaatc cgcctgtgtt ggtcttgcta ccatctacta ttaaaatgtt
    66721 tattattgtt tgcccaccta ttttttgatt ttagtggtat catttttcaa gttcatgatg
    66781 aaattcttat catcagtaaa tgctccagaa aaataaacaa tgattgaaaa atcagttgaa
    66841 acttgaccac cgtttatttt ctccgtattc ttagaataga agggagtctg attgatgtat
    66901 tcactaatga aaaaaatcat taccgaaaaa gatattcgac gtcatgtttc tttagtagaa
    66961 caattgctga atcatacaaa gataaccgta aatgaattag ctgaaatcat agggacaacc
    67021 gaacgaacga ttttttctga ccttcaatct attcgctctc agctgcccga aggctgggac
    67081 atcatcagcg atcaagcagg aatcagtttg caaaaccagc aaaatttatt aacaaatgac
    67141 ctttgggaga tttttttcaa acaatcagtc agtgtcgaac tgctgaaaaa tctgcttttt
    67201 acaaaaaaag ttgctgtccc tgattttcta gccgaccatg ggctttctta tgggacattg
    67261 aaaagacatg tgactaaaat caatcagcgt ttagcaagtt acgacttgca gatcgatttg
    67321 acgaaatata cagcttgtat tcttggaaaa gagcgtgcga ttcgtacttt ttatcatcga
    67381 ttgctgattc ctttcactca taacaactat tttttcgagg attattcgat ccatgaatcc
    67441 cattattttc aatttttaag aaacctcagt caaactgaac tagcggttga aacagaagag
    67501 attttcggaa catgttggtt ctttatcaat acgatccgta taaaagcgaa ttgccgatta
    67561 gattcttcta tccataccaa cagcacactc tcctccctgt atgactctgc attgaaaaaa
    67621 ttgtatttaa cggaaggtat ttatcttaaa gacactgagc tttcttttgc ttctttctgc
    67681 tttctggaaa gttggaatta caacaataac tatggacaag aaaccgctcg ctgcctgcat
    67741 cattctccat ttttagaggt cctcgaaacg tttgtagagg aactagcttc agagctgtct
    67801 cttgatcaac taaaaaaaac atctctgact gataacttgg ctctcctcat attaaaatat
    67861 catgaatcgc cgatattgat tgaagcattg gaccgtcaat accatcgttt tttagaaaca
    67921 tatgatcagc aatatgcaca cttgtatcaa cagaaagaga atttactgaa cgatctaaaa
    67981 aaagaaatag aaatcaatga accaaattac tttctccaac tcttgtctct actgatccaa
    68041 caaacgattt tttctatcaa accgaatttg ttcaatgtct attttatttt ccaaggagaa
    68101 ccttcatgga aggcgttctt gcagcaggaa ttaaaagatt acttaggaaa acgtgtctgc
    68161 ttcttaccta tcgaactaac cgatctttcc actatttctt ttgaaaaaac agatatcttg
    68221 atttccaatt tccctctaga ttctctagat atccctattg tatacatttc ttctattcca
    68281 acgaaaaatg agctcaatcg tttgactgaa ctcactttca aaactttttt atagtaacgg
    68341 ctagcgactg tattctctag ctgttttttc ttttttgcga aacagtttgt tcatgatccc
    68401 tttttctatt tctacaacta agaatagaag aatcacattt gctccaatca ataactgttg
    68461 tgtcatcgtt aaacttactg taccgatcag ctgctggccg actggtagaa aaataaccat
    68521 cccttgcaat aaagcaagga tacctaatga aagaaaaagc gctttgtttt gcaaaagacc
    68581 ttggttcaat gacggcttgg acaactctct gcaattgatc atgtaaacag cttgagctaa
    68641 gacgatattt tgcagaagaa tggtttgctg taagctttgc ccttcaaact gcatagccaa
    68701 taaataggca ggaaccatga tcagtaggga gacatagatg atccgaaaca aatgataacc
    68761 agataggatt ccttgctttg gatctcttgg tgggcgcttc atgatttctg gatctggcga
    68821 ctcgaaccct agtgcataag ataaagtgat tgtcgttacc atattgaccc ataaaatctg
    68881 tactggggac aaaggtagcg ggcgattcag cataagtgcc caaatcaaga tcaatccttg
    68941 agctaatgca gttggcaaga agaaattgat ggttttttgc aaattatcca aaatccgccg
    69001 gccctctttt acggcttttg caatcgtatg gaaattatca tctcctaaaa ccatatcagc
    69061 tgcctgtttg cttacttcac tacctttgat tcccatagca attcctacat cggatctttt
    69121 caaagcaggt gcatcattta cgccgtctcc ggtcattccg acgatttctc catttttctg
    69181 caaagcttta acaattcgca gtttatgttc tggtgtcgtt cgagcaaaga catcgactat
    69241 tggcacttgc tgaatcaact cttcatcaga cataagatcc aaatcgatcc cttctaaaac
    69301 tttggcagta tgttttaagc caatttgttc cgcaatcgct tttgctgtgt ctttgtgatc
    69361 ccctgtaatc attttcactg agatccctgc ttgttggcat tcctttacag ctttgactgc
    69421 actttctttt ggcggatcga tcaatccggc gatccctgca aaagttaatt gggttaaagt
    69481 ctcatgcgtg agttcctgtt tcgaatctac ttttttataa gcaaatccta aaacacgctg
    69541 accttttctc gcaaattctg cagctgtctg actccatgct tcttgttctg cagaagaaag
    69601 agttgattta gcaaataata cttctggtgc acctttgacg taaatcaccg ctcctttttc
    69661 ctccgcatgc atcgttgcca tatatttgta ttcagaactg aacggaatct ttgcttctat
    69721 ttttttcaaa ggtagattgg ctgtttctgt gtgtcgaatc agcgcaactt ctgtcggatt
    69781 gccacttaaa ttttctgttt tctgttcttc ttttgttttt aattcctgac agtttttcat
    69841 aatggacaac acgcaggctt cttcttttgc agctacatcc acaactgtca tttcattttt
    69901 tgtcaatgtt cctgtcttat ctgaacagat cactgtcata gaacctaatg tttctaccga
    69961 aggaagtcct ttgatgatcg ccttttcttt tgccatttca tgtactccaa cggatagaat
    70021 catggtcaaa acagctggca atccttcggg taccattgac accaccaaag caatcgtagc
    70081 cgaaagaaga atatgccaat ccataccata tcgaaatgtc gtaaaaataa ctaagaatag
    70141 gctcaaacaa agaatgcctt gaaaaatttg tttgtttaat cggttgattt ttttaatcag
    70201 aggcgtcgtt tgttgttcga ccgattgcaa tgcttgattg attttaccga tttctgtcgt
    70261 gtttcctgtt tctacaacga caccgactgc agaaccagat tgtacaagcg ttcctgaaaa
    70321 acccatattt ttctggtcgc cgatcgattc ttcttctgtc aaaacggcat gacttttttc
    70381 agatgcttct gattctcccg tcaaaatcga ttcttccact aataaatcat gtgcttcgat
    70441 taatcggata tctgctggaa cgacatctcc ggcacgtaag acaatgacat ctccttttac
    70501 cagttctttc gcagggattt tttcttgcat cccgtttgat agtactatcg cttcttgtcc
    70561 catcagctgc ttcaaaccat tcaatgattc ttccgctttt ctttcttgcc agtaactaac
    70621 gagtccattg acgatcacta cgaataaaat aatacttcct tcaatatatt cactagaagc
    70681 aaatttcaaa aaagaggcaa tgatcaacac gatcatcagc agatcagtaa aatgctttgc
    70741 tatttttttc catcgttttg tctgctgcct tgcttttatt tcattatatc cttgatcagt
    70801 caggcgtttc tgtcgttctt cttgcgacaa gccttctgtt gatgtttgat agtttttcaa
    70861 tacatcttct accgtcaatc tgtaccagtt catcctatcc cctcctgttt aattgatact
    70921 gttattatac gcagggaagt tttttcaggc gtatcgatta tttcaggggg gtctgaaata
    70981 attcgttttg caaaatgtat ctgggcctaa ctgatatttc tattgcttat tcttttatat
    71041 acaaaattta agaatacaaa ccagataacc aataaaaaag gaataaagcg tgtcgtgctt
    71101 tcgaataaca agctgaaagc aattgaagta aaaaacacca acaaagcaag atctttatat
    71161 ctttgtgtag tgttccgttt cttttcttta ataaattgaa catgtgcaca caagatcgaa
    71221 gaccacacaa atagaaaaca actcgttgtc atgcctgcca aaagctgaaa aaacaatcga
    71281 ctatcagcta caaaaaaatg tagacaaaga ccggcaaaaa ataacattcc tgtaattaaa
    71341 ataccgtgta aaggtacgcc tttcttagaa agcgcacaaa accaatgggg caaacttttt
    71401 tcttttgctg tttgatataa aatcctgcta gtactgtaga ctgcactatt tgctgaggac
    71461 aaagaagcaa ccaaaatcat tagattgaca attgctgctc cgccttggca atggatcact
    71521 tgcagcatag tcactaaagg actttctttt aaatctaaac aatgccatgg aacaacaaat
    71581 aaaatcgaca aaatcgttcc tatatagaaa aagagaatac gccaaggcag acagttgatt
    71641 gcttttttca aattcttttg cggatcactt gtctcgccaa cggttaagcc gatcatttca
    71701 attccagcaa aactgaataa aaccatagga aatgagacta ccattccagc aaagccaaac
    71761 ggtagtaatt catcgatctg tccaaaattt tctttgattc cgatagactg ggtatgaaaa
    71821 tctgagacac tcaatcctat acccaataag ataaaaagga aaatccccaa gatcttgatg
    71881 attgagaaaa aagattccaa ttcaccaaac cacttgactg caacaaggtt gactgccatt
    71941 aagatcatta gtgcgctacc tccgcttatc aaagctggta catgtacaaa ccagaaatgg
    72001 atatacaatc ctattgctgt taattccgca agtccagctc caagccagca aagccaataa
    72061 gtccaattga caaaaaatgc ccactttttg cctaaataat agtcaacgaa atcactgata
    72121 gagttaaatg tactatttgc taaaaataaa tcacccatgg cccgcatcaa accataaata
    72181 gccaaaccgc atatcaaata aacgagaata acagctggcc ctgctgatgc aattgccttt
    72241 gctgaaccta aaaataatcc tgttccaatt gcgccaccta atgcgattaa ctggatattt
    72301 cgattagtta gagtccgttt cattgccggt ttttccatca agttcacctt tttctttttc
    72361 aagcagcatg gcgacttcct gttcccaaga aggtttcttt attttttcaa tacagagtgg
    72421 tactacaaac aaaatgacac tgatggctgt gactgcaatt agattgatcc atgttccagc
    72481 tttcatcgtc agtccgacag aaaatccgat tgccgcaaat aaaacaataa cgacagtcca
    72541 aactccaaga ttgctctttt tctctttttt tccaattcta aatggtcgat tcaactttgc
    72601 atgtgtataa cgcaatctca aaactgcgat ccccatgatg acatagacga tacagtagat
    72661 aacagtagtt gaatttacga gcatcaaaaa tgcttgattg acgccaggaa tcagcaaata
    72721 aaaaagtgca aagattgaga taatgacaga ctgagtcaaa ataacggatt tggatacgtc
    72781 aaattgattc gtcttccaaa aattgaattt tggtggatac gcaccttttc tagcactttc
    72841 tgtcactgtc tttgctggtc ctgaggccca agcagataat tggactgcta caccaatgaa
    72901 gacaagtaaa ctaaacagat tcacaataag atgtggcaaa ccaagaattt ggcaataaat
    72961 cgaaatagat tgcgcgatat tattcaattc catttgtcct tttggtacga catttgctac
    73021 aactaaagca ttcaaaatat tgacgaaaaa tataaaaatt aacgcggcaa atactccgcg
    73081 aatatacgtt ttaactggat tttccaatcg agtgatatac acagaggaca tttcgatacc
    73141 agtaaaaata aacatgatcg gcgcaaaata aacaaatgag gatgcagtcg tagtatctgg
    73201 tattaatttg tcccatgaaa aactgcctaa tgttccggtt ggtacgatcc caactttgat
    73261 ccacgcagca aaccctaata agagcatcat cgtcaaaggc acgtacaatc ctaaccaaac
    73321 accgactttt ccgccgattt ttgccatatc aaatttcaaa ttcaaaaaag tgatgatcca
    73381 ataaacgact aaaatgacaa ctaatgtaaa tttgctgttc aaaccaagcg gcacattatc
    73441 gataatatta ccaaacaacg gagcgagtgc tgaagcgacc atcaccatcc caggaaacat
    73501 ttggacccat aacagccatg agacaacgaa cccccatttt tttcctagag cattcgatac
    73561 ccaaagttct ggaccacctt tttggggaaa cattccagca aattcaccag agatcaatga
    73621 gattggaaaa gcgtacaata atactgcaac cagcatgtaa aaaatcatcg tccagctcgt
    73681 tgctgctaca tctggaatat ttcgtacact tgctacaagg gcgcaggtca ttccgataaa
    73741 ggtcatggtc gtgatttgct ttgatgaacc agtatctttc atctttattc cttctttcaa
    73801 tagcgacata tgtttttgtt ttcttttatt tttgttcaag aacagaaatg acaaggtttc
    73861 atcgattcag tacaaaaccc agtatcaccg aaacatccat tgaacgatct tagtgaactg
    73921 ggtttgatac atgaaacgaa cgatccaact tatagaacgt tttataaaaa agaatatctt
    73981 ggcgaggaat atatgaaaaa cagggggaaa tacaattgtt ttgatgaagc aaataattgt
    74041 ctgttctcca tatgtctctt gttattcttt cacacaaaaa tcagttctat tggatgattt
    74101 cgtttagttt cttttccatt gctttggcga ttttttttgt ataaaaattg aaaattcgat
    74161 catcattcaa ataaggagtc atgatagccg cacgtagcag agtgattttc tgttcttttt
    74221 tccattcttc tttcgttaga cccattcttt caacaaaacg aatcggagaa tcaccgtaat
    74281 cttcttgtgt aaatgtagta tgagaagtaa taaaccgttc accataaaca tcgccatcca
    74341 tataagaaga ccgatcgaac attttttcat ttaattcatt gatagcgttc aaatctgtac
    74401 agccttgttc tttgaatacc caattgacca tattaaaatc aggatgattc aatggataga
    74461 cttcgattgt ttttccttta acagtaaaag tcagatgatc gagaaattct ctgaatcttt
    74521 gagctgcctc gattgaagcc ccaatcaatt gaccatatcc ggtcacattc aatggcaata
    74581 cacgatgtgc tgtccagact gcggcggcgg ttgctccagc ttttgatcct tccaaaatat
    74641 aagctcctaa catatctgga gcctttactg atttttcaaa cacatatggc gcgaaataag
    74701 aaatgatatt tctcatattt ttatgtttga ttacgattcc tccagcagca taagggacat
    74761 agcccatctt atgaggatct atcgtgacag aatccgcttc tgaaatagct ctgaaccctt
    74821 catatacctc tttgtcaatc gttacgcagt ggtggaaaac atgatgttct tcaaagaatt
    74881 cagctaagga agcatacggc acaaattctc ctgcttcgtt tagaaacagt gaacgcgcat
    74941 agccgccata tgcggcatca acatgtaaat agaaatagat cccttcatct tttaaccttt
    75001 ctcttaattg gacgatttta tctacactgt ctacttgacc ttcttctgtc gttcctacga
    75061 cagcaaccac acctagaatt gggatttttt gtccagctaa ttcacgaatt gttttttcca
    75121 aagcattaat atccattcga taatcctctt gaactgggat agcaaccatc tgatctaagc
    75181 cgactccgca aatatctaac gccttcatcc aagaatagtg ttttgtttga gggaccagcc
    75241 atttccctaa tctttggata ttttttccgc tacgggaaga agctgctttg acctcatcca
    75301 tttcttcgtc cgtaaagctt tcggtcattt ccaaaatttc ttcaacagat aaattcaaaa
    75361 gttcccactc agacattttt ttcacttttt caggcagcac ttccttgaca gctaaaggaa
    75421 tcgatttgat gcaacgggcg taccataatc cttcaagatt agcaatagaa ccatctgctg
    75481 caatgtgtcc ccatccgtct gtcatattga ataatgaagc aaaatcctgt cctacttctg
    75541 cttccatttg cgaagttgcc atagaagatt ccaatgcaac attatttggg ttccacagca
    75601 tcgcatagtt gtaagctaat aaagcaggca tcaatgtttc agcattcatt tgtccccagt
    75661 aacggcctgc tgaatgccat gggatcgatc ctgcgcgtaa tcgctgactg acttcatcca
    75721 agacctctat catatggtcg cgggtggcta gataatctgg agtgagctta tctccttcgc
    75781 taattgcagg catatctgaa ggaatataat tttctctcca tccaagatgt tcatctacca
    75841 tcttgttcaa caacatttta taaactggtc cattttcagc tttgtcgcct ataaagacgg
    75901 ccttgatatc catatctttc atttttcttc cctccatatt ttgttggtca atgtcttgca
    75961 gatacatgtg tttatctgta acacctcttc actatagcgc caaaaatgag aatttttttt
    76021 ttataacatc aaatccacgt agatttttac aaacaaaaat aaataaagtc ggatttttct
    76081 gataattcaa cgcaaaaaag cgaacaattt ttcaataaat cagtcttcta aaatagataa
    76141 cctaaaaaaa gcgaacaaac aaataaaatg actgtccttc attcactaaa catattttta
    76201 tttttttata ttgttaaaaa ttcgcaattt attttttaat agaattatct gttttccaaa
    76261 ttttataaca t
//
LOCUS       DAMEEU010000005        61534 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.005, whole genome shotgun sequence.
ACCESSION   DAMEEU010000005 DAMEEU010000000
VERSION     DAMEEU010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 61534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.005"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(59..187)
                     /locus_tag="PB779_000352"
     CDS             complement(59..187)
                     /locus_tag="PB779_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDE0737903.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="PB779_000353"
     CDS             complement(190..1563)
                     /gene="rlmD"
                     /locus_tag="PB779_000353"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDE0737904.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(1674..2729)
                     /locus_tag="PB779_000354"
     CDS             complement(1674..2729)
                     /locus_tag="PB779_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDE0737905.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="PB779_000355"
     CDS             complement(2739..4169)
                     /gene="gatB"
                     /locus_tag="PB779_000355"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HDE0737906.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="PB779_000356"
     CDS             complement(4166..5638)
                     /gene="gatA"
                     /locus_tag="PB779_000356"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HDE0737907.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKATFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="PB779_000357"
     CDS             complement(5638..5943)
                     /gene="gatC"
                     /locus_tag="PB779_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HDE0737908.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="PB779_000358"
     CDS             complement(6049..8085)
                     /gene="ligA"
                     /locus_tag="PB779_000358"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HDE0737909.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTVKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="PB779_000359"
     CDS             complement(8102..10336)
                     /gene="pcrA"
                     /locus_tag="PB779_000359"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HDE0737910.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLANPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            10491..12050
                     /locus_tag="PB779_000360"
     CDS             10491..12050
                     /locus_tag="PB779_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HDE0737911.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVEGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQKVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
     gene            complement(12161..14092)
                     /locus_tag="PB779_000361"
     CDS             complement(12161..14092)
                     /locus_tag="PB779_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0737912.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAAAEA"
     gene            complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="PB779_000362"
     CDS             complement(14110..15024)
                     /gene="pfkB"
                     /locus_tag="PB779_000362"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDE0737913.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(15021..15773)
                     /locus_tag="PB779_000363"
     CDS             complement(15021..15773)
                     /locus_tag="PB779_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDE0737914.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLFNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(15932..16141)
                     /locus_tag="PB779_000364"
     CDS             complement(15932..16141)
                     /locus_tag="PB779_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737915.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(16152..17480)
                     /locus_tag="PB779_000365"
     CDS             complement(16152..17480)
                     /locus_tag="PB779_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737916.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            17616..17771
                     /locus_tag="PB779_000366"
     CDS             17616..17771
                     /locus_tag="PB779_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737917.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(17845..18432)
                     /locus_tag="PB779_000367"
     CDS             complement(17845..18432)
                     /locus_tag="PB779_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HDE0737918.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="PB779_000368"
     CDS             complement(18515..19765)
                     /gene="clpX"
                     /locus_tag="PB779_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HDE0737919.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVERAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(20012..21301)
                     /locus_tag="PB779_000369"
     CDS             complement(20012..21301)
                     /locus_tag="PB779_000369"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HDE0737920.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(21455..22387)
                     /locus_tag="PB779_000370"
     CDS             complement(21455..22387)
                     /locus_tag="PB779_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737921.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLNEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(22544..23203)
                     /locus_tag="PB779_000371"
     CDS             complement(22544..23203)
                     /locus_tag="PB779_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDE0737922.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSIYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAIFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="PB779_000372"
     CDS             complement(23206..24231)
                     /gene="sppA"
                     /locus_tag="PB779_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HDE0737923.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELASNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAMR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(24244..24534)
                     /locus_tag="PB779_000373"
     CDS             complement(24244..24534)
                     /locus_tag="PB779_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737924.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAEAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            24944..26749
                     /gene="glmS"
                     /locus_tag="PB779_000374"
     CDS             24944..26749
                     /gene="glmS"
                     /locus_tag="PB779_000374"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HDE0737925.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDSSDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(26821..28176)
                     /locus_tag="PB779_000375"
     CDS             complement(26821..28176)
                     /locus_tag="PB779_000375"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HDE0737926.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(28200..29369)
                     /locus_tag="PB779_000376"
     CDS             complement(28200..29369)
                     /locus_tag="PB779_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737927.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(29366..30253)
                     /locus_tag="PB779_000377"
     CDS             complement(29366..30253)
                     /locus_tag="PB779_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HDE0737928.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="PB779_000378"
     CDS             complement(30442..34122)
                     /gene="nifJ"
                     /locus_tag="PB779_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HDE0737929.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIVPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPAMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLENANPN
                     LAKALFEKTIQDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARAERRKKMEQATKEKKEK"
     gene            34320..34841
                     /locus_tag="PB779_000379"
     CDS             34320..34841
                     /locus_tag="PB779_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDE0737930.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLSCPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
     gene            complement(35540..36105)
                     /locus_tag="PB779_000380"
                     /pseudo
     CDS             complement(35540..36105)
                     /locus_tag="PB779_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(36284..36940)
                     /locus_tag="PB779_000381"
     CDS             complement(36284..36940)
                     /locus_tag="PB779_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737931.1"
                     /translation="MRFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLRAGLITFIS
                     IVGFFLFTVIVFIWRTPAPPLPEITYGEFPFRLEYELNEELHVIEDTLIVEFDGFGMN
                     EGIGRYRRWTSRLASGEDLVLLLEVSDNKQIFYFPGPANYYMGDRLNGYNHTFPSASF
                     IERERGITRRDILHDKELLEQFGPLDQNTINEEELLNQYNIRLVNWEISEPIVNNFGD
                     "
     gene            complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="PB779_000382"
     CDS             complement(37508..38443)
                     /gene="whiA"
                     /locus_tag="PB779_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HDE0737932.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            complement(38477..39475)
                     /locus_tag="PB779_000383"
     CDS             complement(38477..39475)
                     /locus_tag="PB779_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HDE0737933.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAIDR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="PB779_000384"
     CDS             complement(39472..40356)
                     /gene="rapZ"
                     /locus_tag="PB779_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HDE0737934.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            complement(40491..41222)
                     /locus_tag="PB779_000385"
     CDS             complement(40491..41222)
                     /locus_tag="PB779_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HDE0737935.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLQPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTVLQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSKALDTASEK"
     gene            complement(41226..42491)
                     /locus_tag="PB779_000386"
     CDS             complement(41226..42491)
                     /locus_tag="PB779_000386"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HDE0737936.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="PB779_000387"
     CDS             complement(42754..45570)
                     /gene="uvrA"
                     /locus_tag="PB779_000387"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HDE0737937.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQDIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="PB779_000388"
     CDS             complement(45580..47574)
                     /gene="uvrB"
                     /locus_tag="PB779_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HDE0737938.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKAELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQVRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKNAAKALDFETAANVRDMILELKASK"
     gene            47833..49335
                     /locus_tag="PB779_000389"
     CDS             47833..49335
                     /locus_tag="PB779_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HDE0737939.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            49337..50074
                     /locus_tag="PB779_000390"
     CDS             49337..50074
                     /locus_tag="PB779_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDE0737940.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="PB779_000391"
     CDS             complement(50442..51608)
                     /gene="dnaJ"
                     /locus_tag="PB779_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HDE0737941.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="PB779_000392"
     CDS             complement(51759..53588)
                     /gene="dnaK"
                     /locus_tag="PB779_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HDE0737942.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="PB779_000393"
     CDS             complement(53639..54202)
                     /gene="grpE"
                     /locus_tag="PB779_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HDE0737943.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="PB779_000394"
     CDS             complement(54296..55339)
                     /gene="hrcA"
                     /locus_tag="PB779_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HDE0737944.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEEKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            complement(55574..56740)
                     /locus_tag="PB779_000395"
     CDS             complement(55574..56740)
                     /locus_tag="PB779_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HDE0737945.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMRLMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYRDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            complement(56756..56983)
                     /locus_tag="PB779_000396"
     CDS             complement(56756..56983)
                     /locus_tag="PB779_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HDE0737946.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            complement(57370..57626)
                     /locus_tag="PB779_000397"
                     /pseudo
     CDS             complement(57370..57626)
                     /locus_tag="PB779_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320124.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
     gene            complement(57969..58992)
                     /locus_tag="PB779_000398"
                     /pseudo
     CDS             complement(57969..58992)
                     /locus_tag="PB779_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325763.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
     gene            complement(59476..59637)
                     /locus_tag="PB779_000399"
     CDS             complement(59476..59637)
                     /locus_tag="PB779_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737947.1"
                     /translation="MTEKEQVQQIVKKYNKSIADLSENASAKEFKTVMNYVADEANRK
                     QRKLVGLDK"
     gene            complement(59630..60304)
                     /locus_tag="PB779_000400"
                     /pseudo
     CDS             complement(59630..60304)
                     /locus_tag="PB779_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
     gene            60827..61417
                     /locus_tag="PB779_000401"
     CDS             60827..61417
                     /locus_tag="PB779_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HDE0737948.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQKEGWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKKIRLYKLGFYDYYKKYGDPFS"
BASE COUNT        17079 a        13211 c        10646 g        20598 t
ORIGIN      
        1 taaaaagact aagaaacaat aacaaaagtt aacacttctt agtctttctt tagcacgtct
       61 atttattaaa gattttaggg ccttttctca tgtttttacg atcattctta ggtgtttcca
      121 tttgtttgga tcggcctcca ccttgtttct ttttgatcaa ttctttcatt ttttcttttt
      181 ggtccatttt tattctcctt taacgaatga agcgactaat tcgatatgat gggtttgcgg
      241 gaaaagatct acaggctgaa ctttcttcac ggcataacct gcttctgcaa ataacttagc
      301 atctcttgca aaagttgccg gattacatga gatatagacg attcgttctg gtgacatttc
      361 gattgctgat tcaataaaat gatgatctaa tccttttcgt ggagggtcaa ctacgatcac
      421 agatggtttg atcccttttt cttgccattt tttcataact ttttctgctt ttccgacttc
      481 ataatgaaca ttttcgattt tattatttaa agcattgaac tgtgcatctt caattgcttc
      541 tggaataact tccatcccat acaccttatc cactctgtct gctaaagaca agccaatcgt
      601 acctattcct gaataagcgt cgatcacaat gtctttttta tctaactcgg caaactcgat
      661 ggctgtttgg tacagatact ctgcttgttg agtatttact tgataaaatg actttgctga
      721 gattcgatag gtttttccta atagctgatc ttcgatatag tctctgccat ataaaacttt
      781 ttctttgtct cctaaaatca catttgtttt ttcttcattg atattttgga tgaccgaaac
      841 cacttctggc aattcttcat gaatagcttc agcaatttcc ttggatttaa agaatttttc
      901 tttacgagta actaaaacga ccatcatttc atgggaataa tgaccacgac ggataatgat
      961 gtgacgaagc tgtccttcat ttttttcttc attatatcct cgtacttgga accgttgcaa
     1021 gatatctctg actactttga ttgcttgatc gatgacagga tcttggatat aaaaatcttc
     1081 gatagggact agatcatggc tattcttttt gtaaaaaccg gtggctaact gtccatcgat
     1141 acggcgaaca gggatctgtg ctttattacg gtagccgaat ggttctgcca ttccgaccgt
     1201 tggaagtaca ggaacttctg gcatcttagc aatcttcgcc attacatgct ctacttgttt
     1261 ttgtttgaag acaagctgtt gttcatactt caaatgggct aaaggtgcga tacctatgcg
     1321 aagtaatgca ttgttttcta caggctgacg atcaggtgat tgtgtaataa atgtttcgac
     1381 ttttccatat ccaaacttat tgcctgcttt tactactagt atttctactt cttctccagg
     1441 gagtgcattt tcgataaata atggataacc atcgattttt gctaccccca ttccttcata
     1501 actcaagtcg acgatttcga ctgtatatcg ttcgtttttc tttactattt gctgttctgt
     1561 catattttgc tcctttaagc ctatttttca atcctactga actctactat aaatcagcta
     1621 attacacaac taaaaccggc actgacctta ctacgttcag caccggcttt tgattaattc
     1681 ttttgattag gtgtttcgtc tgctattttt ccgtcaccgt cgatatcttc atccgttaaa
     1741 cgttcgactt cttttacgaa ttctttgctg acaacctcta attcttcttc atctgtacct
     1801 gtgattgctt catcaggaat ctgatcggta ttggcaaaga actcaatgtg ttgatgaaga
     1861 ttttggaaat gcatcggtgc ttccccgccg tattcaccat ctaagttgat cattactggt
     1921 cgattgatat catcttctgt ttcaacgaac aaactgcttg ttttggtata gattattctt
     1981 ggatcatcga catgtcgacc gccattcagc atgagtgctg caatatgcaa gatctcaaag
     2041 atatttgctg tcttcacaat gattaaagaa aacttcccat catccaattt ggcatctggc
     2101 gcgatctgtt cgaatcctcc aacagagttc gtcagcccta ggaaaaacat cgaagcattt
     2161 ccgatatatt ccccttcatc atacttcaag cgcattttga ttggctttac tcgagggagc
     2221 atctctgctc ctttcgcaag ataagcaaga taaccaaaaa tactctttag ttctgatgga
     2281 acttcataag tcaattctgt caaatagcca cctgcagcga tattgatgaa gtaactgtta
     2341 tcagaaaggc cgatgtccat ttttacggtt tggtgttttt ttatcacttc tgctgctgct
     2401 ttaatattat ctctaggaat ttttaatgct cgagcatagt cgttcgttgt accagctggg
     2461 atgatggcca ttttaggacg gtgttcaagc ggagcgattc cattaaccac ttcgttgatt
     2521 gtgccatcgc caccagctgc cactactaga tcaaaaccta gttctgcgac tctacatgct
     2581 tcattcttgg ctgaatctgg ttctggtgta gttgcatagg cgctggcttc aaatcctgct
     2641 tcttctaatg cctgtaggat atccgccaaa ttttttttca ataattcttt tcccgaggtg
     2701 gggttataaa ttacgcgtgc ttttttcatt ttcagcctct atcgtttcgc taattcatct
     2761 ttaagtagct tattcacgac accaggattt gcttgtcctt tagttgcttt catgatttga
     2821 ccgactagga agccaaccgc acgatctttt ccatttttga aatcatcgac agattgttgg
     2881 ttgttatcca aaatttcatt aatgattggc agtagtttgt tcggatcaga taattgcacc
     2941 caaccatttt tttcaactac ttcttgggct tctccgccat ttgtgatcaa ttcacggaag
     3001 acttttttgg cgatttttga gctgatcgtt ccatcggcga tcaaacgaat cattcctgct
     3061 aagttctcag gtgtcaattt tgtctcagct aattccagtt tctcactgtt caagtaagca
     3121 gaaacttcac ccatcaacca gttagatgct tgcttggcat ctgcaccatt ttccaaaaca
     3181 gcttcaaaaa aatcagacat ttcttttgta agtgtcaata ccattgcgtc atactctgga
     3241 agtccaaact cacggatata gcgttcgcga cgagaagctg gcatctcagg caaactagct
     3301 tttacttttt gaatccattc gtcatcgatc acgaatttcg ggatatcagg ctctgggaag
     3361 taacgataat cactagaccc ttctttgaca cgcatcaaaa ctgttttatt cgttgtttcg
     3421 tcaaaacggc gtgtttcttg ttggatttct cctcctgaaa gaagaacttt tgcttgacgt
     3481 ttttcttcaa aagctaaacc ttttttcacg aaagataaag agttcaagtt tttcaattct
     3541 gctttcgtac cgaactcttc ttgtccataa gggcgaagag aaatattggc atcacagcgc
     3601 atagagcctt cttccatttt cacatcgctg acttctgtaa attggataat tgatcgcaat
     3661 gcttctagat aagcgtatgc ttcttctggt gaacgcatat cagcttcaga aacgatttcg
     3721 atcaaaggcg tgccttgtcg gttcaaatca acgtaagaat aaccgccaat accatgcatg
     3781 ttttttccag catcttcttc taaatggaca cgttcgatcc ggattttttt ctttttacct
     3841 tctacttcga tttcgatcca tccgtcatga ccgattggtt gatcaaattg ggaaatttga
     3901 tatgcttttg gattatctgg gtaaaagtaa tttttccggt caaaatgagt atctttagag
     3961 atttcacagt ttaatgccaa agctgctttc atcccgaatt ccagcgcagc tttattcatt
     4021 actggcagca cgcctggata accccagtcg atcacgtttg tattgctgtt tggttctgca
     4081 ccaaaatgag ctggcgctgg agagaaaatt tttgagttgg tttttaactc gacgtggact
     4141 tctagtccaa tgactgtttc aaaattcatt cgtctttccc tcctaaaata gctggttgtt
     4201 gtttatggaa ttctgttgct tgttcaaacg catatgccgc ttgatacatc gttttttcat
     4261 caaaataatt accgatgatc tgcaatccaa ctggtaatcc ttctgataaa cctgccggta
     4321 cagacatacc tggaagtcca gccaagttga cagggatcgt taagatgtca ctcatgtaca
     4381 ttgtgattgg atcgttaatg ttctcaccga ttccgaatgc aactgttggt gaagatggcc
     4441 cgatgatcaa gtcataatct gcaaagactt tttcaaaatc tcgtttgatc aatgtacgga
     4501 cttgtcccgc ttttttgaag taagcgtcat aataaccagc acttaaggag aatgtaccta
     4561 acatgatacg gcgttttact tcttcaccga atccttctga acgtgagttg acatatacat
     4621 catctaatga tttcacattt tctgagcgat aaccgtagcg gataccatcg aatcgttgca
     4681 agttggaact tgcttctgat gaggcaatga tataataaac agccacaccg tattttgaat
     4741 gaggcaagct gacttcttcc acaacagcac ctaatgaacg gaatgtttct gctgctttca
     4801 atacagcttc ttttacgcca ggggccacac cttcgcctaa gtattcttta ggtaaagcaa
     4861 tcttcattcc tttgatgtcg cctgtcagtc cctctgcaaa atcaggaact gaaacgcctg
     4921 aagaagtacc gtctttttcg tcataaccgc tgatagctgt caatgctaat gcattatctt
     4981 tcaccgtacg ggtcattggt ccgatttggt caagagatga agcaaaggca atcaaaccaa
     5041 aacgtgagac acggccataa gtaggtttca tccctacgat gccgttaaaa gctgctggtt
     5101 ggcggatact tcccccagta tcactaccta aagaaactgg aatttgtcca gctgcaactg
     5161 ctgctgcaga accaccagaa gagccaccag gtacttttgt tgggtcccaa gcattttttg
     5221 ttttcttgaa ataagaagtt tctgtacttc cacccatagc aaattcatcc atgtttagct
     5281 taccaacagg gatcatatct gcttgataga ttttatccat gaccgttgca tcataaattg
     5341 gttcaaaatt gtaaaggatc ttagatgcag cggttgtcaa gatatctttt gttacgatat
     5401 tatccttgat accaattgga ataccagcaa ggacgttgct ttcatcaatc cctttttcat
     5461 ctaaagcttt tgcctgttcc aatgcttttt cttcgttcaa tgtaatgaat gcttcgacct
     5521 caggctctgt ttctttgatt cgttcaaatg ttgcttttgt caaatcttgt acagtgattt
     5581 ctttcgatac aagcatatga tgcagttctt ctagagaacg attgtgtaat tctgtcatta
     5641 tgcgccagcc tccccattat cgatgattgc gggtactttg ataaagccgt cttctgtttc
     5701 cggcacattt ttcaataatt catcgcggtt ccatccagct tgcgcccgat cttgtcgcat
     5761 cacgtttact gtttcaacca cattcgacgt aaatggaaca ccttctgtat ctacttcttc
     5821 cagcatttca accatatcga tgattttacc taattggtcg gtaaaacttg caagttcttc
     5881 atctgcgaac gcaagttttg ctaatttggc aacgtgtttc acttgttctt cactaatcgc
     5941 catactaccc cttctttcta aacgagttaa aaactttgct ctctatttta acacaagagt
     6001 gccgtgtctg aaattgttta ttgaaatttg tctgaaaaaa ctcatttttc attcttctac
     6061 tgagcgactt ttagccaatg catctgccat ttgatcttct gtccaaactt cgattcctaa
     6121 ttcttgtgct ttggtcagct tgctgccagc atcttctcct gctaccacga tatccgtttt
     6181 tttcgatacg ctaccagtca ctttcccgcc aagattttcg atcgtctctt ttgcttcttc
     6241 acgagtaaat cgtgttagtt taccagtaag gactactgtt ttttctttaa aaggagactc
     6301 gacttcttgc aattgggcat ttcgaagccc tttgtattcg aaattgacgc ctgcttgttt
     6361 taattcattc atcaattcat ggacttcttc gttactgaaa taagtgacta cactgtcggc
     6421 aatgatatca ccgatcgtat caagcgcaat aatcgactca tagtcacttt tactcaatgt
     6481 ttctagatca ccgaaatgtt ctgctaaaat ttttgctgct ttcgctccga catgtcggat
     6541 tcctaacccg aaaatcaacc gctcgaccga attatctttg ctgttgtcga ttgctgtcaa
     6601 aatattattt gctgattttt cttttatttt gtccaacgtc aataactctt cttctgtcaa
     6661 tttgtaaaga tcagcaacat ctgctactag ttttttatca tacatctgtt ctagtacgcg
     6721 cggccccaac ccatcgatat tcatcgcatt tcttgaaaca aagtggttca aaccttcttt
     6781 catttgagca gggcatttag gattgatgca ccgtaaggct acttcttcat ccaaatggac
     6841 aagttcactt ccacaaactg gacaatgtgt aggcaattgg tattcttcgc tgtctttagg
     6901 tcgtttatct aacacgactt gcgaaacttc tgggatgatg tctcccgctt tataaatcag
     6961 aactgtatct ttcaagcgga tatccttcaa cttaatataa tcaccgttat gcaggctggc
     7021 acggcttact gtcgttcctg ctactcggac tggtgtcatg atagctgttg gcgttactac
     7081 ccctgttcga ccgactgtcc attcgatgtt ttcgattagc gtttcaactt cttctggcgg
     7141 aaacttgtaa gctgctgccc atctcggtgc tttgacagta aaaccaagtt gatcttgtag
     7201 cgagaattca ttcactttga tgacgattcc atcgatttca tagggcaaat ccacacgttt
     7261 gtcatgatat tcttcaatgt atgaccacac ttcatcaatc gaatgacata gacgtttttc
     7321 ccgattcgtg tggaatccaa ttttttctag ctcttctagc gcatcatact gggtttttgc
     7381 ttgcatagga ccgaaatcag ctactgtgta taaaaaagtg tccagatttc ttttcgctgt
     7441 gattttagaa tctaactgac gcaaagaacc agctgcggcg ttccgaggat tcgcaaagat
     7501 atcttttccc tctgcttctc tgtcttggtt caattggaca aatgaccgtt ttggcatgaa
     7561 acattcgcct cttacttcga tgttcattgg ttcttttaat ttgattggga ccgaccggac
     7621 agtttttagg ttttcagtga tgttttctcc tacagttcca tccccgcgag tcgcacctct
     7681 cacgaaattt ccatcttcat aacgcaaaga aacggaaagt ccatctattt ttagttcaca
     7741 gcaatagtca actacacgtc ccactgcttt ttgtacacgt tgatcaaaag ctatcagctc
     7801 ttctttgctg aaaacgtcgt tcaaactgta aagcggaata tcatgagtga ctttttcaaa
     7861 accttctaat acttttccgc ctactcgttg agtgggagaa tcagacgtga tcaaatcagg
     7921 atattgttcc tcaattgcta ctaattctgc gtattcttta tcataaacat agtcttccac
     7981 tgttggttta tcttctacgt agtattcgcg agaccattgg ttcagtcttg tacgaagttc
     8041 ttctgctcgt ttagcagctt cgtcaatcgt catttcatgt tccatcattt accctccact
     8101 actaagcttt ttcaattggc gcaaaggcag ccaaaagacg ttttactcct tgacttggga
     8161 aagccacatc tagttctaga tccttcgacg tcccgcttac tcggacgact gttcctagac
     8221 cccatttttt gtgtttgact ttatctccag gtttccagct gttattttcc cctccagtag
     8281 cacttttaga gggaacaacc gctgtctctg gctgtttata gctatatgct gtttttttag
     8341 cgaatacagg tgttttttta ggcgtaggac gcatgccttc gatttccagt aactcctgat
     8401 cgatttcttc tacaaaacga gaaggtcggt tatattgcgt ccgtccatat aatgttctgg
     8461 agaaagcatt tgttaaatac aacgcttctt ctgctcgcgt gatccccaca tatgcgagac
     8521 ggcgttcttc ttccagttcg ctttcttcca tcaatgctcg agataaagga aaaaccccct
     8581 cttctagacc aatcaggaat acaactggga attctaatcc tttggctgca tgcaaagtca
     8641 tcaatgtcac ttgggaagca tcttcttcta aattgtcaat atcggaaaca agtgccagat
     8701 catttaagaa gaccgttagt ttttcttctg gtgcatcagc gtcttcttca ttttgctgtt
     8761 cgaattgttt gtcgaattct tgtgtgaccg ttaaaaattc ctccaagttt tcgatgcgtg
     8821 cttgtgcttc taatgtattt tggattttta agtcttctag atatccgcta cgatccaaaa
     8881 cctctttcgt caattctgtc actgtcaagt atgggatcat ctgagtgact tcttggatca
     8941 tctctccaaa tgcacctaat tgctgtcctg cttttccacc gatatttgcc agatccacat
     9001 tttgcgctgc ttcaagcagt ggccattcat gaagagaagc aaaactgcgt agtttttcga
     9061 tagatcctgg tccgatgcct cgtttgggcg aattaacgat acgctcaaaa ctgattgaat
     9121 cttgaggatt tgccagcaca ttcaaatacg ctaaaatatc tttgatttct ttacgatcgt
     9181 agaacttgtg ccctccaacc attttataag gaatatttgc tttcaacaga gtttcttcca
     9241 ttacacgaga ttgtgcgttc gtccggtaca agatggcaaa gtcgccgtaa ttccgatgat
     9301 tgcttcgaat ctcttcttgc atccgatcta cgataaaacg ggtttcgtct cgttcattat
     9361 ctgcacggta gtaagtgatc ttgtttcctt ctttgttttc tgtccacaag ttttttggtt
     9421 ttcgattgct attgttttca atgacttggt ttgctgcgct aaggatgttt ttcgtggagc
     9481 gatagttttg ttctagcaaa attactgcag catctggata atctttttca aaatccaaga
     9541 tgttctgcat atctgcaccg cgccagccgt aaatactttg atctgcatct cccacgacgc
     9601 acaggttcct aaatctacct gccaataaat tgactagcgt atactgtgcg tgatttgtat
     9661 cttggtactc atctacatga atataatgga atttgttttg ataatatgtg agtgaatcag
     9721 gatgttcttc aaataatcga atcgtattca tgatcaggtc gtcaaagtcc atacattgat
     9781 tatattgaag ctctttttgg taagcagcat aacattttgc cgcaatctct tcgtaataac
     9841 tgccttgcat ttttgcaaaa tcctgagggg tctgcaggct gttttttgct tgagagattg
     9901 ttcctaatat acttcgagga tcatattttt tcggatcaat gttcagttct tttagtatcc
     9961 gtttcatcaa ggtcagctgt tcagaagaat cgatgattgt aaagttccgg ttatacccga
    10021 taaaatcaac atctcttctt aaaatacgca cacacatcga gtgaaaagtc gatacccaga
    10081 catcttcgcc tccagatgcg agaatcgcat tgacacgttc tttcatttct tttgcagcct
    10141 tattggtaaa agtaatcgct aggatgttcc aaggattgac ttctttttcc tcaatcaaat
    10201 aggcaatgcg gtgtgtcagc actctcgtct ttccacttcc tgcacctgcc attagcagta
    10261 atggtccgtc agtgtgaaga acagcttctt tctgacgggg gttcatcccg tttaataatt
    10321 cagctttgga tgacattaac aacatccttt cttttatcaa tcttgttaat tatagcattt
    10381 tcttggcttt cattaaacta gctagttcaa aatcatttgt ttctttttat ggatttttcc
    10441 ttgtcaattc gttgatttcg cgctaaatta aaagaaagcg aggcgtttga atggaaaaaa
    10501 aaggaaaaat caagaaatta gataagactc agatatattt tattctaaaa ggaatatttg
    10561 ttggactgct gacaggaatc gtcgttagcc tgtttcgatt atctatcgaa aagctaagcg
    10621 atttagttcg aagtatctat gaaatgagtc gggaacagcc gatttactta attggcctag
    10681 ctatttgctg catccttgca gcatttttcg tgggttatct ggtcaaaaat gaaccggata
    10741 tcaagggaag cgggattcca caagtagagg gacagcttcg cggggaatta tcaatgaact
    10801 ggttctctgt tttatggaaa aagttcattg gcggtgtact ttcagttggt gcgggccttt
    10861 ttctaggtag agaaggacct tctatacagc ttggcgcatc cattggacaa ggagctggac
    10921 aattgtttcg gagtccatct tcagaagaaa agattttaat ttctagcggt gcaagtagcg
    10981 gacttgcagc agcattcaat gctcctatcg caggattact ctttgtttta gaagaaatcc
    11041 atcactcctt ttctccactt gtttggctga catcatttgc ttcagcaatc actgctaact
    11101 tcgtctctct ttactttttc ggcttgagac ctgttttata tctaggtgac cttccttctt
    11161 tgccgttgaa atattatggt tccttagtga tcttaggagt acttctaggc atcttaggtt
    11221 ttatttatca gaaggtcttg ctggctttgc caaaatttta caaccgattg cctttaccag
    11281 cttattttca cgggttcgtt cctttcttgc tgattttgcc aattggttat ttatggccta
    11341 gtactctagg cggaggcaat caaatcgttt tagcttttgg acatgcttcc ttgccaatca
    11401 ttatgattat cggtttgttt gttcttcgat tcgttttttc catgatttct tacggtggtg
    11461 gtcttccagg ggggattttc cttccgatat tgacattggg ggctttaatc ggtagctttt
    11521 atggaaacat tatggttgat ttcgggatgg atccaatcta catcaaggat tttgtcgtta
    11581 ttgccatggc tggttatttc acagcgattg gaaaagcacc gctgacagca attattttag
    11641 tgacagaaat ggttggctct cttaatcatc tgatgccttt aggattggct gctcttgttg
    11701 cttatatcgt caatgacctt ctcggcggta atccaattta cgaatcatta ttggaacgtc
    11761 tacttggaaa tactcagacc gcctcactaa aaggtgcaag gacaactttt gattttccag
    11821 taacggcaga gagttcttta gacggattaa tggtacgaga cttcaattgg cctaaaaata
    11881 tgctgctaat ctctatacgc agaggaaatc aggaaatctt gactcacggt gatacgatca
    11941 tgaatgtagg agatattttg gttatcttga ctgatgaagc aaacttgcca agaatcaagc
    12001 aggaaatcga ggctaaatct tctatcacaa atttgaagca atcattttaa cgaacatgga
    12061 aaaactattt tacaacaact attcatctac actacttgat tctatatgat tctataaaaa
    12121 aagaagagac tgggaaaaac cagcctcttc ttttttattt ctatgcttct gctgctgcag
    12181 gagcttttct caataaacca taaatcacac cagatacgac tgctccgata gcaataaaca
    12241 ccaaatacat gaccgggtga ctcagtaaga atacaacgaa aatcccgcca tgaggagcca
    12301 gtaatttgat cccgaaagct ccgactaatc cgccagttaa agcagaacca ataataaaac
    12361 ttggaatggc acgaatcggg tcagctgctg caaatggaat cgatccttcc gtgacaaacg
    12421 atagtcccat cacgatgttc gtcaaaccag catcttgatc tgttttgctg aatttattct
    12481 taaacaaacg tgtagcaacg aaaattgcca atggaggtac cattcctcca gccataacag
    12541 aagccatcac gacacttccg ccagttgcaa cagtcgtagc taaagttgct gtaccaaaca
    12601 cataagcggc tttgttgatt ggaccgccta aatctgccgc catcattcca gctaataatg
    12661 caccaagtaa agcagcattc gaaccactca tacttgtcaa gaaaccgttc aatgcatcat
    12721 tgattgcttt catagggaca ttgaccagca acatcaagaa accagtaatc agtaagccaa
    12781 acactggata aaagaggatc gttttaattc catccaatga ttttggtaag ttcttgaata
    12841 atttacgtaa aaatacgatg acataaccag ctaagaatcc accaatcagt gcacctaaga
    12901 atcctgcacc gcctgtatta gctaatgcac cagcagcaaa tccaacgatc aaaccagggc
    12961 ggtcaccgat acttgaagca ataaatcctg ctaataccgg cagcatgaaa ccaaatgcag
    13021 cttgtccgat ttggttgaac cagctagcag cttgattgta attccctaga tttgataatt
    13081 gatcatgtgg cacgccaata aattggtcga tcatgaaaga aagcgcaata gcgattcctc
    13141 caccaataac gaaaggtaac atgtgtgata cgccgttcat caaatctttg taaattcttt
    13201 gtccgatagt accatccgca tttccttctt ctgaactgct ttcttttcca tcaccatgga
    13261 atactggtgc agtaccacta agggctagat tgatcagctc ttctggttta cggataccat
    13321 cactgacagg acgattgatc agttcttttc cgtcaaagcg attcatctct acttttttgt
    13381 ctgctgcaac gattacacct tctgcacggg cgatgtcttc agcagtcaat cggtttttga
    13441 ttccttctga accgttcgtt tcgactttga tctccacacc catttctttc gcttttttct
    13501 tcagagcatc ttctgccatg taagtgtgag cgatccctgt tggacaagct gtaacggcaa
    13561 caacgaattt tctttctgga tgagcagaag cttctgcagc ttgtgtttct tgttctgctt
    13621 tttcttctgc ttctttttgc tcttcagctg tttggaacaa gtcttggact tcttctggtg
    13681 tatttgcttc ttttaatttt cctacgaaat ctgcatcaat cagcaatcga gatagtgctg
    13741 ctaatgcttg caaatgtgtg tcgtttgcgc cttctggagc tgcgatcatg aaaaacagat
    13801 aagttggctg tccgtctaag gcttcataat ctactccttt ttggcttttt gcgaataaaa
    13861 ctgttgcttc tttaactgca ctgtttttcg cgtgaggcat ggcgattcca tcaccaagac
    13921 ctgtagaagt ttgtgcttcg cgggctagaa ttccttcttt atatgtttcg atatcggaaa
    13981 tccggccggc atcaaacatt ttttggacca tttcatcgat tgcgcctttt ttatcagtcg
    14041 cttgcaaatc catgatcatc gcttctttga ccattaaatc cttgatattc atgattatcc
    14101 tccttgaaac taatcaattt ttgtgatttc aacttctggc agcaactcat caatcaattc
    14161 gcgagctgcc aagtcatcag aaaaagctgt tgcgcttccg caagcaactc cccatttaaa
    14221 ggcttcgatt ggatctttcg tacggctgta agccccaata aagccggcaa tcattgaatc
    14281 ccctgcacct actgaatttt tcaatgggcg aactaataca ttcgttttat aagttccttg
    14341 ttccgtgaag agcaaagcac cgtctccagc cattgagatc agcacattct gtgccccttc
    14401 agctagcaat tttttaccat acggaatgat ttcttctaca gattggaagg ttgtattgta
    14461 aagctcagct aattcgtgat tgtttggttt gatcaacaat ggtttcttaa caagtgcatt
    14521 ttttaggtca tcacctgttg tatcaatcac gaaatctgca cctttttctc gaatgatatc
    14581 aatcagttct tgataaaatc cttttcgcag gctagccggc gcgcttcctg acaatacgac
    14641 gatatctcct tgtcctactg ttcctaatgc ttgcttcaac tcatcgattt cttcatctga
    14701 aatagatggg cccaaaccgt taatttcagt ttcagtatct gattttagtt tgatattgat
    14761 tcttgtatct tcttttacgg ttgtgaacaa agactggatt tgttcttttt caagccactt
    14821 cgaaataaat tcgccagtga accctcctaa aaaccctagt gctgtagatt gagaatcgat
    14881 ccgtttcaaa atacgggaaa cattgatccc ttttcctcca ggtaacttga agtcttcctt
    14941 cattcggttc aaatcgccta gttttaaccc atctacgcgt acgatataat caattgatgg
    15001 attaagtgtt actgtgtaaa tcattgtatt gcctccttaa ttgttgtctt ttcacggaat
    15061 tcattaacga attctaatgg acaacgctcg gttatgatcg tggctgcttc caaaggtgca
    15121 acagaggtga aggacaactg gttgaatttg gtatgatcaa tcaatacaaa tgtctcttcg
    15181 gaatttttca tggctaaacg tttaacagct gcctcttctg ggtccggagt cgtgaatcct
    15241 tgttcaagat gggcaccgtt cattcccata aatgctttat taaaatgaaa attttttagt
    15301 tgttctatcg cattagatcc taaaacagca ttagttgcca gctttatcgt tccacctaaa
    15361 ataatggtag caagctccaa atcaactaaa tttgccgcat gttgaacgga atttgtcact
    15421 actgtgatct gttttccttg cagaaaagga atcatttcta acgtagtaga gccagcgtct
    15481 aaataaatga catcttcgtc attaatggtt tcagctgccg atttggcgat ttgctgtttt
    15541 tcgtgaacgt ttttgagtga tttttcactc atattctgct caaaattcaa taattgctct
    15601 ttcttagctc cgccatgaac tctttctaga aacccactat tctccagctc ttgtaaatca
    15661 cgtcttatcg ttgattcaga agcattaaaa aggtttacaa gatcttgtga tttcacgatt
    15721 ttctgctgtt caagcaagtc taggattttt tgtctacgtt cctctgtaag cattttcacg
    15781 atcacctcaa tacaaataat agcatatttt ttttctactc gcaatataaa tcagtcaaaa
    15841 acgttcataa aaattataaa tcagtcaaaa aaaaataaaa aaccagtcaa aaagactggt
    15901 tttttatttt tttgtctatc atcaagccgt tttatcgttt tttattttcg cttcttgttt
    15961 ttttcatata aacagaagca ggttttcttt ccttatgaag aagataataa taaagtccca
    16021 tcccgccaaa catgaccaaa aaaccgatga ctgatcgaat aggaaaatta ggaacaaaaa
    16081 agagacagac ggataataat gatgccggaa ccattattcg ataatagagt tgtttatcca
    16141 ttttcttcac ctcatatttt ttgtaaagta atcaattgtt ctaattctcg gtaatctaaa
    16201 aattgcacac gcagatgctg ctcacctttc ttgacatcga attggatact tcgccgcttt
    16261 ttctttattc gtttgaaggt aacatcagag agtctatgtt tgatttcctt taacggtaat
    16321 tctgacaggg attctgaagg aacatagatt cttaaggata aaagatactc ttgatatttt
    16381 tcatctgtta cctctacttc tagatattcc ctaatataat aacaataagc ttcgattcca
    16441 ttatccaaag caacagtcgg atcgataact ttatagcaca tcatgcgcga gcgattctcg
    16501 tcaacccaag gaaaatacgc ctgagcattt agtgttccgc gaacacgcct ttctttataa
    16561 tctccttgtt gaatatcata actttttgtt acaaaaaatg aagcattctt tttaggaaca
    16621 ggttgcattt gtgcattctg atactggaca gattggatcg tatggtcagt gtaaatgtat
    16681 tcaacgaatg gcggtttcaa taaaccgaca ccattgtccc aagcaagatg atcaaaccca
    16741 agctggtccc taaaatagga ttgaaacatt tgattgtttg gcttttgcca gttaaagggg
    16801 tctcgataaa gctggataca tatgacttcg ttttctaatt ccttcacttt ttctacttgt
    16861 tggatgtcga gaaaaatcgg tttagggatg atttgatgat aatagcgact ataatacatt
    16921 tcccaacacg aagtgaaaca taaaccttgg taaaaaagat cgtatcctgg aaattggttg
    16981 caatcgacta ctacttcccc gttttgttgt ttcattttag gtaaatgttc gatttcatcc
    17041 tttttctcaa acaatagccg ttgagagatc tgttttgtat tgtgatagat aaactcgcta
    17101 taagctcgca tataggcgaa caccccatga gcaatcattt ttttctgaat gaagtctcga
    17161 atcaaaaatt gcttttcttt gaaaacagag atagacaata cattttttat caataattga
    17221 ttatcttcca agcgaaaact acattcgttc tcgtcatttc ctacaactaa ccaactttcg
    17281 tctcttaccg atgctagcat tattttttct tgaagctttc gaagatcata cggatccgct
    17341 tgttgtgtga aagagcggat aaatgttggc tggatcaaca gacgtgtcaa aatagcccaa
    17401 tcgcttattt cctgtttttt ttcttcttca tttaagtctg tgagctggat agtcatcaat
    17461 aatttatctt cgccaatcat tttctcacct ctttaaaatc tttttataat ttaattataa
    17521 ccaacgataa agaaaaacta aaactttatg tcttagaaac caatttggac gattacatga
    17581 tagactaagt aaaaagaaac aaagaggtgt ttacaatggg gttgaaattt gaacgtacag
    17641 ataatttaga taaacttttc gaatcatttg ctgtcgatcc ggaaaaaaca gttgcaccaa
    17701 aagaagagat cgatcgattt ctaaaaccac agccacaaaa tgaaaagaaa aaagacaaga
    17761 aacaaaagta agttaagctc aaaaaaagac ttaccagcca aacttttatg aaagagtttg
    17821 actggtaagt cttttttatt ctttttatga ttcaattgct tgttcgattg ctgcccacgc
    17881 ttcttctttt ccctgttttg taacggaaga aaagagaata aacgtgtcat tgcgatcaaa
    17941 atccaacgct tttttgattt cgctctcatg cttgttccat ttaccacgag ggatcttatc
    18001 tgccttagtg gcaacaacaa ttacagggat atcataatac ttcaaaaatt gatacatctg
    18061 gatatcttct tgagaaggct tatgacgcaa atctactaaa gaaacgaccg cacgtagctg
    18121 gtctctagtc gttaaatatg tctcgatcat ctttccccat tttgctcgct cagttttgga
    18181 tacttttgca tacccatatc ccggaacatc gacaaaatgt aatgcgttct cgatcaaata
    18241 aaaattcaat gtctgggtct ttcctggctt accggaagta cgggctaaat tctttcgatc
    18301 aatcaatgtg ttgataaaag aagatttccc tacatttgat cgtcctgcca gagctatttc
    18361 tggcaattgt gtatctggat attgttttgg tgccactgca cttatgataa tttcagcttg
    18421 atggactttc atggtctctc tccttaacaa ggtgatgaat aaagcaagcg gctgtcgcaa
    18481 aagccaaaat gacttttacg gcagcctctt ttcatcaacc cgcttttttc tctgaatctt
    18541 tatagattac tgttggctca ccagacaatt cagctgcttc ttttgtgata atcacttttt
    18601 cgatgttttc atttgaaggg atatcaaaca tcacatccat catgatttct tcaatgatgg
    18661 aacgaagtcc tcgagcaccg gtattgcgtt cgattgcttt tttcgcaatg gctctcaacg
    18721 cttcaggttc gaattcaagt tcggtattat ctagagaaag aagtttttga tattgtttga
    18781 ctagcgcatt tttcggctca gtcaagatcc gtaccagatc atctgttgtc aatttctcta
    18841 aagctgccat aacaggtaat cgtccgataa actcagggat caatccgaat tttagtaaat
    18901 cttcaggaat gatatgctgc atgacacttt cgtcttcaga aagtttttgg ttttgtgtac
    18961 caaatccaat cgtcttttcg cccatacgat tcttcacaat cgtttcgatg ccatcaaatg
    19021 caccacctac gatgaacaat atgttcgtcg tatcaatctg aataaattct tgatgtggat
    19081 gtttacgtcc tccctgaggt ggcacgcttg caacagttcc ttctagaatt ttcagcaagg
    19141 cttgttggac accttcgccg gaaacgtcac gagtaataga tacattttcg cttttacgcg
    19201 caattttatc gatctcatca atatagatga tccctttttc tgcacgttcc acattgtaat
    19261 cagcagattg aagcaattta agcaaaatgt tttctacatc ttcccccaca taaccagctt
    19321 ctgtcaaact tgtcgcatct gcgattgcaa aaggtacatt caatgttttt gctaatgttt
    19381 gtgctaaaaa tgttttacca gaccctgtag gtccgatcaa gcagatattg cttttttgca
    19441 gttcaacatc atctgtgttt tcttgtgctt gctgattgac acgtttatag tgattgtata
    19501 cggcaacagc taacgagcgt tttgcgcgat cttgtccaat cacgtagtta ttcaatactt
    19561 caagaatttc tagtggttta gggacttcag tgaattcgcg tacagcttct tcataaaatt
    19621 cttcatcaat gatttcttta cataggtcga tacattcatt acagatgtag acccctggac
    19681 cagctacgat ctttttcact tcttcttggg ttttcccgca aaaagaacag cgtacggtct
    19741 cattgctact tggattgtca tacatggtct tcacccctta acttgcaaaa agtatgcaag
    19801 aaactatcaa agactttaca gtcttttact atcataacat agtttagtaa aaagaaaaag
    19861 tgtttaacaa aggatcaact gacctatacc tttgcatttt ttactcttaa caaaaaataa
    19921 ggaactgtga caaaatcgtg tcacagtccc ttatttcgaa taaacaattt tctagaagta
    19981 gcttcttcag aaatgattta ttacttgatt tctattcttt cgcttctgtc gctgtacctg
    20041 tgatcaattc gattgctttt ttcattgtca catcatgttc cagcatatct tctgtcaaca
    20101 cgcgtttgat ttgttcgatt ggcatgttgt atgtttctga taattcttgg atttctgcat
    20161 tgatttcttc ttctgttgct tgaagatttt cagcagctgc aattgcttcg atcacaagat
    20221 ttgttcttgt gcgcatttct gcttcacctt cgaattgttt atgcaagtct tcttctgtag
    20281 aaccagttaa ttgatagtac atttcaggag agataccttg acgttgcatg ttgttcaaga
    20341 attcgtccat tgaacgatgt acttcatcat gaaccatcac gtgtggcaat tcaacgattt
    20401 ctgcgttttc aacagccata cggatcgctg cttcatcttt tgcatcgtcc gctgcttttt
    20461 cttttgtttc tactaattct ttgcgatatt tttctttcaa ttcgtctaat gttgatactt
    20521 cgtcatcaac atcttttgcg aattcgtcat ctaattcagg cacttctttt gcttttactt
    20581 catggattgt cactttgaag actgcttctt ttccagcaag atcttctgct tgataatctt
    20641 ctgggaaagt tacatttaca tctagacttt cacctgattt atgaccaact aattgatctt
    20701 caaaacctgg aatgaatgag cctgaaccta attcaagtga gtaattttcg ccttttccgc
    20761 catcaaacgc ttcgccatct acaaagcctt cgaagtcgat tactactgta tcgccatttt
    20821 cagctgcagc atcttctttg ataactaatt cagcttgtgc ttcttgttca cgtttgatac
    20881 gtgcatccac gtcagcatct gttacttcac ggtcttgttt ttcaacaact agatctttat
    20941 attgtcctaa ttttacttct ggtttcactg ttacttcagc agtgattacc cagtcttgac
    21001 ctttttccat gctttcaaca tcgatttttg gttgagaaac aggatcgatg ccagcttctt
    21061 tgacagcagc ttcataagct tctggtaata cagcattcaa tgcatcttca tataaagctt
    21121 cttcaccgta catacggttg aatacttgac gagaaacttt ccctttacgg aatccaggta
    21181 cgttcaagct ttttttcact ttattaaacg cagttgttaa tcctttttgg atttcgtctt
    21241 gcgcaatcgt aaattttaaa acaccatcat tcgtgccttt tttttcaaat gttgcagtca
    21301 tttaattccc tccgagttta gaaattcatt ttatacatca aaaacgtttc atgcatacct
    21361 ttaaatagta cactaaccct ttcaaattgt aaacatattg aatggataga atccttgttt
    21421 ttcataacat ttttatcttt ttcactgata aaatctaatg gaagaagatc atttgctgca
    21481 aaattttttc tctttttttt aaaaaatctt gtttttcatc ttctgtacct tcatacatcg
    21541 tttttcctgt acacgcctct acagtcagtt gaaaccagcg cttcgggtct tcgatgtatg
    21601 tatcatagac aggataaaca attgcagatt gcaacgtgaa ttcttcattt aacacggaac
    21661 taagcagcgc atcttcatta ccgtaacgat ctgaaaatac acataattgc tggtaacttg
    21721 cctgctgctg cggctttggc agatcttttg gtatgacttt gactaacttt tcttcaatcg
    21781 tcaaatagaa aacaggatgg cattcgttca attgcctaag tgtctccagt aattttgccc
    21841 ttgctaaaat atggacctct ggcgatacaa taagtttact cgctgtttgg ataaactcat
    21901 gataaggaag ctgttcgatc tcatcaatag acgcaagctg acgtgcaggt tccaacgaag
    21961 gaagttcctc cgatttattg tggagtgcct tgatcttctg cctctccatt tgtccggata
    22021 attcttctgc aaattggatt ttttcaatga cccgctgctc gaaagcttca taaaaatctg
    22081 tacttgctat caattttcta gcatataaaa aatcttgtgt actgattaac aagtcaaaat
    22141 aaaattcagc aaactcctca ttttgaagat actgtttttc atgcaagagt gcttgcttca
    22201 atgcttcttt tttctcgtcc aactcgtaaa gacaaaaaac aagcaggcta ttagcctcaa
    22261 agctttcttt caactcgtaa gctcgttgaa ataattcttt tgcctgctga tattgctggt
    22321 ttgctagtgc ttgttgtgct actcgcatta aattctcata tttttctgga aaatcaatcg
    22381 gcttcacgca gtgtcctcct cttgctcatg ttcagctcat gttcaatagt agcaaaacaa
    22441 aaaaagcatg acaattaaaa ataactgaag caccctctaa aagctagatt ttagatctga
    22501 cttttagaag gtgctttcaa ctgttactgc tttttattgc tcatcagctg ttgacttcct
    22561 ggttgaatgc tttgatcaga ttgatcgtaa caacacttgt attagtgaaa aaatcgccta
    22621 gatgttgctt tttctgatta aagattgctg gaagataccc taacatcagc aaaggaaatt
    22681 ttagaatgaa ccggcaagca ccttctctaa ctaaaacggt tgaccagcta agttcttctt
    22741 catcaaagct gatgactcga ataccaaaga tcattttccc aatcgtttga ccatgattga
    22801 atttcgtcaa taaaataaaa tacgctagat aaataagtaa ggctgtgaat ccgtagatac
    22861 tcagataaga atctgaaaaa ttaagccaac ctagattttt ggcaatacca agtgttaaac
    22921 gcgtaatagc tccgatacac aaaagatcga ccaagaaagc aaacattcgg ataaaaaaac
    22981 ctgcatagaa atacttagga aaatcatttg cttttggcgg ttcatttctt gtgtccgtat
    23041 actttttcca tttacgttgt ttctttttga tttcttcggg cgtcaaaggc tctctttcaa
    23101 aagagctcag taccttttgg gaaaagttgg agtcaggtcc tacagcaggc tgctgttgct
    23161 tatctttttc ttgttcctta ttttcatttg aaagctctga catgcttact cacctccgta
    23221 ataatacatt gcttttggtg attccgctgt ccctagattc tcaagaacgg ataagatctg
    23281 actagtctca gaaggcttca atccctggaa ttctgctagt ttacttccta accatgtact
    23341 agcaaaccca gatggcgtgg aagaatattc tactagttcc gcatcttcaa gctgttgttc
    23401 ctttcgcata gcttttaaag catcttcagg aaatcccaat tcatcgacta aacctacttc
    23461 ttttgcttgg acaccatcat aaatccttcc atcagcaatt tttttgactt cttcttcaga
    23521 tttattccgt ccctcgctga cgattgctac aaaacgacta tatgcgctgt cgatatatgc
    23581 ttgaagcacc gcttcttctt cttttgtctc tggtcgcgtt cctgaaccca tatctttcaa
    23641 cgctccgctt ttaactgttg tatcttccac acccagtttt tctagaagtc ctgaataatt
    23701 caatcctgac atgatcacac caattgagcc ggtcactgtt tcttctgttg caaagatttt
    23761 atctgcttga gcagaaatat agtagccacc gctagctgcc atgtttttca tgctgacata
    23821 cattgggata tcatgttctt tacgaatcgt atccaatttc ttagcgattt ccgcactttc
    23881 gtagacaccg ccaccaggag aatttacttc taaaaagata cctttgactg ttggatcttc
    23941 ttcaatcgcc ttcagttgtt ccataaaatt tttatgattg taaccttcag aagcaaataa
    24001 acctgaagac cctcccgcag caatcgttcc atctactgat aattttacga ttttttgcgt
    24061 actgtctccc tcttccaaca catttgaagc tagttcttca tccccatata accaactgtt
    24121 caatccctca atttgatcgt tttcctgagg cttagtcaaa ctagctgaaa ctaacgaaac
    24181 cacaaataat cctgcagcaa tcagaactgc tgcccaacgt ctcttattca ttctttctcc
    24241 tttctaatac aagtttttta tgacgatcac agtttctgac tgctcagaag tgtcgaaccg
    24301 ctctgctttt tcttcccgcg catacccgga aaacgactct tttgtcaatt catcttctac
    24361 cgtaaactca cgagcttcag caacttccaa ggcatcaggt gcgatttctt ggatgctatc
    24421 ccagccagta tctaaaaata ttttcgtatc atctgataca ccagctgatg cttcgaattt
    24481 ggacaattgt ttttttaaca ttcccagtgt catgatctca atttttgaat ccatttttac
    24541 tcctcctcta tccgattact ttctattgta ccgaactcct gaaaaagatg atagataaaa
    24601 acccattatt ttttgacata aaaagagcat ttgacaaagc atttgatata taccaattta
    24661 ttttttattc tttttttgtt gacaagaaca ttcgcaaaag gttatgattt taaatgtttc
    24721 cagataaaaa acaaaagagg aggatagtta taccttttag gatagcgcca ggtctgtgta
    24781 aacagatgac gaggagaggg tttatcgaaa gattcggcgg atggccctag ggactgcact
    24841 ctacagaaaa tccacaaaaa atatctgcaa agataaaaca aaaggatttt cctgcagctg
    24901 gaagcattca tacgaattca ttatagaaag taggatgttt tttatgtgcg gaattgttgg
    24961 aatgattgga ttaaaaaatg taacaccagg attgattgac ggtctagaaa aattagaata
    25021 ccgtggttat gattcagctg gtatctttgt ctcagatggc acaactgatt atctggtcaa
    25081 agcacaaggc agaattcaaa atttgaaaaa caaaataaat attgatacta caggaaatat
    25141 aggtattggt catacacgct gggcaactca cgggcaacct tctgaagaaa acgcccatcc
    25201 acatacttcc caaagtggac gcttcgtgct cgttcacaat ggcgtaatcg aaaactttga
    25261 agaacttaaa attgcttatt tagcaaatga ccactttatt ggtgagaccg atactgagat
    25321 tatcgctcat ctaattgaaa ctttcgcgaa ggatactaca acgcaagagg cgtttttaaa
    25381 agctttgcgg gtcatcaaag gttcttacgc tttcgctttg attgatcgga cagcacctga
    25441 tgttatttac gtcgctaaaa ataaaagtcc actattaatc ggactcggcg atggattcaa
    25501 tgtgattgcc agcgatgcaa tggctatgct tgctcatacg aaggaattcg ttgagattga
    25561 agatgaagag atggttaccg tcacatcaga aaaagttatt attcaaaatt ttgcaggtga
    25621 catcgtagaa cgttcttcat tcgaagcaca agtagattct tcagatatcg agaaaggtac
    25681 ctatcctttt tatatgctga aagaaatcga cgaacagcct attatcatgc gtcgtatcgc
    25741 tcaaaaatac gtaacagaag acaatcgtgt ctctcttgat caaaagctgg tcgatacatt
    25801 gtctgatagc gatcgaatct atatcgttgc ttgcggaact agttaccatg cggggttagc
    25861 aggtaaacag actctggaaa aattgacaca gatccctgtt gaggttcatt tagccagtga
    25921 atttggctat aacacacctc ttctttcaaa aaaaccattc tttattttct tgagtcaaag
    25981 tggcgaaaca gcagatagcc gccaagttct ggtaaaaatc aaccgtctcg gctacccttc
    26041 acttacgatt acaaatgttg ctggttctac tctttcgcgg gaagcatcct ttacactgct
    26101 attgcatgct ggacccgaaa tcgcagtagc atcaacgaaa gcttatactg cacaaatagc
    26161 tgtactaact ttattagcca aagctatcgg tgataaaaaa gaatttgaaa cttctcttgt
    26221 attcgatatc actcatgaat tgagtttagt tgctaatgcg atggaatcgg tcatcgccca
    26281 aaaagattat ttagaagagt tggcagaagt atatctcagc gatacaagaa atgcctttta
    26341 cattggacgt ggcgctgact acaacgtttc tcttgaagct gctttgaaat tgaaagaaat
    26401 cagttatatc caggcagaag gttttgccgc tggcgaattg aaacatggaa cgattgcttt
    26461 gatcgaagaa ggaacaccag tgattggaat catcagtgaa gaagtgactg gtgcgcatac
    26521 tcgaggaaac ctgaaagaag tcgaaagccg tggcgctaaa acactagtta ttgtctcaga
    26581 gggattagaa aaggaaagtg accagctggt gctaccaact gtccaccctt atctaactac
    26641 tctaaccaca gtcgtaccga ctcaattact tgcatattac gcaacgctat tacggggatt
    26701 cgacgttgac aaaccacgta atttagcgaa atcagtgaca gtagaataat aaaagaacaa
    26761 ggaccagtgt cagacatctg acactggtcc ttgttctttt attttttatg aaaatatctc
    26821 ttaatccagt ccgatttctt ctttgactac tgccgcgatt ttatcgacat agtaattaac
    26881 tttctcatca gtaggcgctt ctgccatcac tcgaagtaat ggttctgtac cggaaggacg
    26941 aactaggatt cttccttctg atcccatttc agcttctgcc tcttcaatca cttttttgat
    27001 tgccggaaca tccatcgcac cgtttttatc acttactcgg atattcacta atttttgcgg
    27061 atagattgtt acctctgctg caagctctga taatttctta cctgtctgtt tcatgatatt
    27121 cagtaactga attcctgaaa gcatcccatc tccagttgtg ttaaaatcta agaaaatcat
    27181 gtgcccagac tgctcgccgc caaagttata atcgtttttg cgcatttctt ctacaacgta
    27241 acgatcacca acttgtgtaa cgacatcttt caaaccgatt ccttccaccg ctttgtggaa
    27301 tcctaagtta ctcatgacag tcgtaacgat cgtatctttt ttcaatcgat ttttttctgc
    27361 caagtattta gcacagataa acatgatttt atcaccgtcg acaatgtttc caagttcatc
    27421 caccgcaata atacgatcgc catcgccatc gaaagctagt ccagcatctg ctcctttttc
    27481 aacgaccatc tcagctaaac gttctggatg ggtagagcct acgccatcat tgatatttaa
    27541 cccgtctgga tttgtgccca tggtataaaa atctgtttca agatcggcaa acaaacgatt
    27601 aacacttgtt gaagttgctc cgtttgctgc atcgacacaa atggtcaaac cggaaaggtc
    27661 accgttgatc gtttgtacaa ggaattgaga atatttcaat aagccttctg gaaattcttc
    27721 tacagttccc aatccttcag ctgatggacg aggcaattca tccacttcag catctaataa
    27781 tgcttcaatt tctagctctt ggtcatctac tagtttaaaa ccatctgcac cgaaaaattt
    27841 gattccatta tcttgtgctg gattatgaga agcagaaatc atgacccctg cgcttgcttt
    27901 ttgcaaacgt gtcagataag caacacctgg tgtagagatc acacctagct ggaacacttc
    27961 gatacccacc gataaaagtc ctgaaatcag cgcttcttct aacatttgac ctgagattct
    28021 tgtatcccgc cctactaaca cgcgtgggcg ttttccttct tcttcatgct ggcttaggac
    28081 ataacctccg caccgtccca gcttaaatgc aagttctggc gtaagttcct tgttggcttc
    28141 accgcgtacg ccgtctgttc caaaatattt acccatagtt gtaaaattac tcctttaact
    28201 taattttctg aggaatttgt tctgctcatt tgtgttgatt cgcttgtttc tgatgtttct
    28261 tctgtacttg tggtcgagct gcttgtccca gattccgaac tggaagaaat ggttgttgtc
    28321 gatggttccg ttcctgaatc agcagatgaa atacttctac tcgtacttgt attttcttgt
    28381 gtccgactgc tcgtcgaagc agagctactg cttgacgttt gcaacacggg tgtaatctcc
    28441 acactaactg attcgggctt gatacttaac ccctcttcta ctggtatttc aattttacga
    28501 gttgttcgat gattgatacc tgagacattg atcggtacag caatactgtc accgatcgat
    28561 gcaagcaaat cgctagagcc gcttacttct gcttccagtt ttgaaaaact gaaatcatag
    28621 ctttctaccc cggcagctgg tgttccttgc tgtatcccat aaagtcgtac cgacttgctt
    28681 ggcttgatcg aatcagctct cactgttact tgcactggat cagagacgat acttaatact
    28741 tcccctgctg cattcagcgc ctgtattggg acctcactat taatcccatc atctgtgacc
    28801 atcgaagcgt ccacatcagc tactactcgt ttgatttctg ccaatgtttt gtcacctgta
    28861 gtgatagaga cttttttagg actaacggaa gtatcatcaa gttcatatcc agatggtgtg
    28921 aacgttgaag gaatcaacgt ttccacatcg aaatctttta ttaccttttt ctcaaccgtt
    28981 actgtaatag tcgatggttc gatctttgct gtgacagcac tgctcaaatt ttgaattttt
    29041 agcggaacct catgtgttcc ttcgcccagc ttagtgatat ctgctgtgac gcggaacatc
    29101 cgtgtatctt cgtttgcctc tgcattcaac tgaactcggt ttgcactgga aagtttgaca
    29161 gtcactgcat tttcatatcc atggatatag tagcgctttg aatcataaga aatcttgatt
    29221 ggcaccccag taactgtttg attatacgct tcatttccag aaagcgtatt tggaacggac
    29281 tggccatttg cattgaagta cagcgcaata ctgaacagca atgcaataaa actgtaaaga
    29341 atgcttgtcc gtttctcttt tgagatcatt tgcgatcccc tcccttagtc ataccgtcta
    29401 ggaaagattg aatcacgttt ttcttgtttt ttgttttctc ttcagcaatc agttctctac
    29461 gcaaaattgc caaatattct tgctgggata agccagccat cagttcatta tctaatgtaa
    29521 tgctgacatc cccagtttct tcagagacaa cgatggtaat cgcgtcgctg acttcgctta
    29581 taccgacagc tgcccggtgt cgagtcccga attcttttgg aatcaacata ctttctgata
    29641 gaggaagata ggcgcttgct actgcgatct ttccttcttt tacaataact gcaccgtcat
    29701 gcagcggtgt attaggaata aagatattga tcagcagctc tccagtgata tctgcatcta
    29761 atgcaattcc tgtctcaata tactcatcta atccagtatg ccgttcgata gtaattagcg
    29821 caccgatttt tcgcttggac atatattgga tggctttgtc aaaagacaag atcatcttct
    29881 catcttcctg ctgttcgctt tttgattgtt tgaaaagcga actgcgtcca agatgttcca
    29941 gtcctctccg gatttccggc tgaaaaatca cgatagcagc tatcaccccg tacgtaatga
    30001 cttggttcat cagccaagac aaggtgtgca gaccaatgat ttccgctacg attcggataa
    30061 caataaaaat agctacacct ttcagaagct gaatcgcttt tgtgcctcgc agcagttgga
    30121 tcagtttgta tacaagatac cagacaacca gaatatcaag tatgttcacc aaaaaattca
    30181 gagagaacaa gtcaccggaa aacatttgct gccaatagtc caaattaaaa agttccccga
    30241 tttgaaatga cataaaaagc ctctcttctc ttttgagatt tcctctctag tatatcatat
    30301 gttttaattt tagaggctga tctgctcgta tttttcttga gaaaaacgca taattttcag
    30361 gaaaattgca agtatgcgtt ttatttttct ctgcaataaa tatttttaaa cttcagagaa
    30421 ttattcatta tattttttct gttatttttc ctttttttct tttgtagctt gttccatttt
    30481 tttacgtcgt tctgctctgg cagctcttct ttcttctgct tcaaggtccg tcgttttttc
    30541 ttttctagtc ttaacgggta catcgataga ttcctctggt tcaagtcgtt tcttgatttt
    30601 ttctaattct cccgtcagtg cagcatagtt gtaaaaacgt gttttagcgt cttggatagt
    30661 cttttcaaat aaagcttttg caagatttgg atttgcgttc tctagcgagg aaaagcgaac
    30721 ttgtttcctc atgaaatcag gcatagcaga gaaatcaggt tttttgtagt ccaaagtcat
    30781 tgggttcttg tttttttcga ccattgcagg gttatatcga tataatgacc aatagccaga
    30841 agaaacagct tcttttgctt ctttaagcga ttctttcatt ccaccaagca aaccatgtgt
    30901 gatacaaggc gtataggcaa tgattaaaga aggtccagga tacttttctg cttcttcaaa
    30961 agcctttatc gtctgcattt gattggcacc tgaagcaatt tgcgccacat aaacatttcc
    31021 atatgtcatc gccatcattc ctagatcttt ctttgaagca tactttccac tagccgaaaa
    31081 tttagcgatt gccgaagctg gtgttgcttt tgaggtttga ccgccagtat tggaatagac
    31141 ttcgttatcc aaaacaagaa tattcacgtc tgctccgctg gcaagtacat gatcgatccc
    31201 gccaaaacca atgtcgtaag cccatccgtc tccaccaatc atccattggc tgttttttac
    31261 gaatagatcc tttctcttgt atatatcctc cagttcaggg acaattgatc gttcgctttc
    31321 gatcgcagct tgcagttttg ctgctctttg ctgcgttcct tcgctctcaa acatgtgtac
    31381 caaccagtct tccatcaatt ctcgtagttc ttctgatact tttggcaata cttctttgat
    31441 tgaacttgcc aaagcctcgc gacgagtctg tgccgctaga agcataccat aaccaaattc
    31501 agcattatct tccaataaag aatttgacca tgcaggccct tgaccacatt cattggtcgt
    31561 ataaggagaa gcaggagaag caccgcccca aatagaagaa cagcctgtcg cattcgcgat
    31621 catcattcga tcaccgaaca tttgtgtcaa taattttaca taaggtgttt cgccacagcc
    31681 tgagcaagcg cccgagaatt caagaagcgg ttgattgaat tgtgtagaca agacagtatt
    31741 ctttcctttg actggatttg ctttttgtct taatgtcatt gcaaaagccc aattcacagc
    31801 ttgttctttc tgttcttcat aaggcttcat cactaaagct ttttcttttg cgggacaagc
    31861 ctctacacac agaccacaac ctgtacagtc ttccactgaa acttggatac ggtattttac
    31921 gccgtctgcg cctcgcattt ctctcacgat aaatccttct ggcgcttctt ccatttcctc
    31981 ttcatctgct aaaaatggac ggatggcagc atgaggacaa acaaaggcac attcattaca
    32041 catcgtacag cgatcactaa tccactcagg tacttctaaa gcgacgcccc gcttttccat
    32101 agaagccgtt cctaaaggca tttcgccagt tgtcattcca tttgctacaa gtgtaccaac
    32161 agagagttga tttccttcct gtgcattcac tggttcaagt atttcttgta tataaccagt
    32221 gttcctttta ttgatttttt caggcatctc caacgttctc caatggtctg ggatcgcgac
    32281 ttgatgaagc agttcggtcg tccgatcgat tgcttgtatg tttttttcta cgatagccat
    32341 tgatttatgt ccatagcttt tcagggcttc ttcttttagc agcggaagca cctcatcaaa
    32401 aggaatgatg tcagctaatt taaaaaaagc cgtttccatt gccgtattga tccggcgtcc
    32461 caaaccgact tcttgggcca atctcatggc attgatcgta tagaatctaa tgttattttc
    32521 agccaagtaa cgttttaatt ttaagggcag atgcgtttct aattgttcgt cgctccaaag
    32581 agtattcaat aaaaaaatgc cacctggctt caatcctttg accaagtcat agctatgcag
    32641 gtaagctggt gtgtgacagg caacaaggtc cgcatgctcg acaagatacg ctgaacgtat
    32701 cggcgtatct ccaaaacgaa gatgagagac agtcagaccg ccagattttt tcgaatcata
    32761 ataaaaatag ccttgcgcat atttatcggt gtgatctcca ataatcttga tagctgattt
    32821 atttgctcca actgttccgt cagatccaaa tccccaaaac ttggcctgga atgtttgcgg
    32881 ttctgtcaaa tccagacttt cctttggttc caaagattga taagtcacat catccacgat
    32941 ccctatggta aaccgttttt tgcgtatgct tgggtctttt ttcaattcat caaaaactgc
    33001 tgagatttgg tcgggagtca catctttaga ccccaatccg tagcgaccac caataacagc
    33061 cgggcgaagt tcagaatcat ataacgcact ttgaacgtct aataagagag gttctccacc
    33121 tgcccctggt tctttacttc gatcaagaac agcaattgtt tttactgtat gaggcaactt
    33181 ttgcacgaat gtttccactg gaaaaggacg ataaagatgg atattcaaaa aacctgtttt
    33241 ccgtccgttt gcattcaagt aatcaatcgt ttgttcaatc gtctgtgcaa ctgatcccat
    33301 agaaacaatg acttcttccg catcgtctgc tccgtaataa gtcaccaagt cataagaagt
    33361 tcctcgtaat cggttgatct ctttcatata tttttgaacg atttcaggta atttatcata
    33421 ataggggttg atcgtttccc gttgttgaaa atggatgtct ggattctggt tcgtaccact
    33481 aacagtcgga tgattgggat tcatccctcg tttacgaaat gaagctaatt tctcctgatt
    33541 gatcagagga gctaattctt catattccaa aacttcgatt ttttgaatct cgtgactcgt
    33601 acggaatcca tcaaagaaat tcaaaaaagg tacttctcct tcaatagaag caagatgggc
    33661 aacaggtgct aaatccatca cttcttgtac actgctttca gctaacatag caaatcctgt
    33721 ttgtcttgca gccatcacgt ctccgtgatc tccgaaaata ttcaacgcat ttgtcgtcac
    33781 tgcccgacta gcaacatgga aaacacttgg cagtagttcc ccagcaatct tgtacatatt
    33841 cggtatcatc aaaagcagcc cttgagaagc ggtatatgta gttgtcagtg caccagtttt
    33901 caatgatcca tggaccacac cagctgctcc tgcttcggat tgcatttcta ctacttttac
    33961 tggttgaccg aatacatttt cttttcctgc tgctgaccat tgatctacta attcagccat
    34021 ggtcgaactg ggtgttattg gatatattgc agcaatctcg gtaaatgcat aagaaatata
    34081 tgcggctgcc gtattgccat ccattgtttt catttttcgc atgattcatc atccttgttc
    34141 atattctctc ttattatctg ttccattata acgtaaaaca ttccattttt tcttttattt
    34201 ataaaaatat ttcacatatg tctatttgaa ttggtcatct aatttttaga caaacagtct
    34261 aaatcgttgc ctttttttgt cagacatgta taaactataa gcgaaagagg tgttttaaca
    34321 tggatatatc agtgattgat gcaacgaaaa caaatacaca aaaaggaatc ctttatggtt
    34381 catcgaatgc tcctaaaaaa atggtcgaat tcatcaacct atcttgtccg tattgccgac
    34441 aatggtttga agaatcttat gagctattag aagaagcagt ccaaagcggg caattgcagc
    34501 gagtgatcaa attgttcgat aaagaaaaag aaagcttgca gcgaggaaac gtgatgcacc
    34561 ggtatctcac aatcagcgat ggtcaaaaag cgatcaaaga gatcaaacaa atattcgata
    34621 ctcaagacga gtggaaacat ctttctctcc aagaagtagc ggattttgca gtagataaac
    34681 taaagctgac agaacaaaaa gacgaacagc tgagccaagc tgtcatcaac gaagctgagc
    34741 aagcacatat tcgatttgtt ccgactgtca tcttgggtaa agaaatcttt gatgaatcta
    34801 tttcaataga ggaattaaaa gaattgatcc aaacaaaata aaaaaataag gagcgtagga
    34861 caaaagtaaa gaacactttt gtctcacgct ctaaacacct ataaacggcg gaagcagaag
    34921 caactccttc ttatttcttg gagttaaacg cttctgtccc agcctcctta ttccgaataa
    34981 atggtgtcca aaagcttgca tctgccagat tatctcattt cttatgacaa gctgagcaaa
    35041 ttatctccac caaataattt attcatattt ttgacttgcg catactaact aattcttaaa
    35101 ttttcataca aaatttctca aattccctta acgagtaata tttatgtacg gtgattcaca
    35161 ctagtatccc aatcactttt taagttatcc cgatttcaat tctacttcaa aaatagttgc
    35221 ttttatgtat gctgttagtt gattagatgg tcgtttgttg agctaggtcg tttattttaa
    35281 acaagttgtt tctttagctt atacctatct cgtctaccaa acgcaagatg gcaaacacaa
    35341 atgcatacgc atctgtattt gccactttga ttcgtataaa gctaacaact cctaactcct
    35401 ctcatttaat agttgctctc ttttttattc agatacattt ttgctgatca cagcctagta
    35461 tttcaatggt tttgaacact aaaccaaatt gttccattac aacattcact ggctgatgaa
    35521 atggattaat agatttcgat tattcaaagc gattttctat tggtggattg tgttcccaac
    35581 taacaagacg gattccaaag tcattatata actcttcaag agttaaccct ttcctgttcc
    35641 caatagatgt atctctccca cgctcgatat aaaatatgga gtttcgaatg ccaagacctg
    35701 gcaaatcttt ccttgttaca gttacactgc tactaacttc cccatataaa atccagctcc
    35761 tccaaaatga taatatattt ttcgaccatc atctaactca tgtaacaata attgttgtgc
    35821 cctcttgtca ctcgccaaat gcaaacgcca cgtgcgatac catgccatgc tacctgcatc
    35881 tgcagaaaat ccatcaaata atgcaacaat tgtatcttct atcacaatcc tttccccatc
    35941 tacttcatat tctaatctaa aatcaaactc ccctcgggta atcgcaggtc ttggtggctt
    36001 aggacccaat attattctac ttaaaaccgc attcgttccc agatgaaaca cagctataac
    36061 aacaataatg attaatattt tgtttctatt tgataaattt ctcattattc gcaaatcacc
    36121 tctacattct cacatactag ttcgtaatac tcctttaata tcaaaatatc tactgatcgt
    36181 aataatattc gctatgaatt cctactactc gtataagaaa ggccaaatca tcagctttta
    36241 cttgctgatg atttggcttg tttctattta tcgtaattgt tttctaatca ccaaaattgt
    36301 taacaatcgg ttcagatatt tcccaattca ctagccttat attatattga tttaacaatt
    36361 cttcttcatt tattgtattt tgatcaagcg gaccaaattg ttctaataat tctttgtcat
    36421 gtaaaatatc ccttctagta atgcctcttt ccctttcaat gaaagaagca ctaggaaaag
    36481 tatgattata accattcaac ctatctccca tgtaataatt agcaggtcct ggaaaataaa
    36541 atatttgctt attatcacta acttctaaca gcaacactaa atcttctccg ctggctaaac
    36601 gacttgtcca tctacgatat ctccctatgc cttcgttcat tccaaatcca tcaaattcaa
    36661 ctattaacgt gtcttctatc acatgtaatt cttcattcaa ttcatactca agtctaaaag
    36721 gaaattctcc atatgtaatc tctggcaatg gtggtgctgg agttctccaa ataaatacaa
    36781 taactgtgaa tagaaaaaat ccaacgatcg atataaatgt tatgagacct gctcgaagta
    36841 aaacccgata taataaaaat gctgtatttc gctttgctat atctagaaaa ataaaaagta
    36901 ctgcaatcat aatgatagta aaagttgtaa aaaaacgcat ttttgccctc cctttataaa
    36961 catcgattct caaattctaa accaaatctt ggtagttcaa gttcaggtat aacgtattcc
    37021 aaccatacat ctcaattact atttatgaac ttatgattat cactgaataa atcactccat
    37081 ccccttgtta aaacttctac attaattaca cctggttgtt ttcgactagc taatccaatg
    37141 aacttatcaa ccatccttat ccaccaacca cgagaatctt gaccagaagt aagaagagca
    37201 gttctcaagg atgatcgagc agttccttcc agttttttaa ttaatcaggc cagttataga
    37261 taaatacttg atcttatcta tatcaggact tctatattaa gcaaaaattt atgtacaaaa
    37321 ctaaaatctt cattcagttg tctccccgct ttttatacga ttgtattaaa aacaatagaa
    37381 gcctttccaa attatgttac tccagtaaag atggaattat agtttgacgg aagaaaagca
    37441 agtataactt ttaaaaaaaa ctgatacatt cgcatctcct gcttcatgta tcagtttttt
    37501 ctttggatta aactgcttct tcacgcagtt tttccgcaaa ttcatttatt ttgcgaattc
    37561 ggtgattaat tcccgatttt gatatcgcac ctgagggaat catttcccct aattctttca
    37621 agctgacctc tggatgttga agccgaagtt ctgcgatttc ctgaagtttt tcaggaaggg
    37681 catgtagacc gacctttgct tcgatcaatt cgatgttttc gatttgttta gaagccgcat
    37741 caatcgtctt gttcagattt gctgtctcac aattgactag acgattgacc gaatttctca
    37801 tatcccgtac gattcgaaca tcttcaaatc ggagcattga gttggttgca ccaatcaatg
    37861 ttaagaaatc agcaattttt tctgctcctt ttaaataaga aatatagcca ttgcgccgtt
    37921 caagcgttcg agcatgtaga ccgtaataat ttaacatatc gcaaatgtct tggttatgct
    37981 gttcataaat agaaaatatt tccaaatgat aacggctcgt ttccggatta ttgactgaac
    38041 ctgaggccat aaaagcacca cgtaagtaag aacgcatttt ttgcgaattt cccataatct
    38101 cgtccgaaac gtgtccattg aacatcatac catccatgat atcaagatcc atcaacacat
    38161 cttttgtgcc ttgcttcaac cggacgatat agacattgtt cttttttaat ttcatttttt
    38221 tacgaacgag tagctcactt cgtacctgat aatgatcttt caaaagagaa tagatacgtc
    38281 tggcaattgc agcattttct gtttggacgt tcaaaataaa ctgctggttc acaataccta
    38341 aagagccgtt cattcgcagc aaagcagcta attccgcttt cgcatgttct cgatgaactt
    38401 ccaaaccagt tagttctttc ttcacatctg cagcaaatga catcctattc tcctcctttc
    38461 tccaacaata aattgcttaa tattttgaac cgaaaactaa acggaacaat tcttctacta
    38521 ctttgtctcc atcgtggaag acaccaccat ctttcaattc caaaaagtcg gtggaaatca
    38581 ctcgacatcc ttcatttctc aatccgttga agtcgtgtgc gacttgtact agatactcat
    38641 catagatctc tgggtccata taatcttcag gcactttttc cgtattgacc aatactgtat
    38701 cgataaaagg ctgattcaaa tgcttgtgta aaacacgtat atgatcggca tctgtgaaat
    38761 gttccgtttc ccctttttgg gtcatgatat tacagatata gacggtttca gcagttgtct
    38821 tgagcattgc ttcgccgatt tctggtatca ctaaatttgg aaggatactg gtgaataaac
    38881 ttccgggtcc caaaacgacc atgtcggcgt ccataattgc tgaaacgact tttcgagccg
    38941 ctttggcttc acttttatca tttgtgttgc agacatacac acggtcaatg gttttacggt
    39001 cgatcgcgat tttagattct cctactgcag tcgttccgtc tttaaagaca gcatgcaagg
    39061 tcaaaggagt ttctgaagaa ggataaacat gtccatctac atgcatcatt tttgctaata
    39121 attgaatcgc ctcataagtg cttccccgca tctcggaaac tgcggcaatg atcagattac
    39181 cgatcgtatg attggctaaa aactgatctt cctttttgaa acggtattgg aaaatatctt
    39241 catagaattg tggcatatcc gataacgcca ctaagacatt tctcaagtca ccaggaggag
    39301 ccatagcgat cgattctctg attgcaccgc tgcttccccc atcatctgca acagtcacta
    39361 ctgctgtgat atctgctcct tgatttcgca aacttttcag gataactggc agaccagtgc
    39421 caccgccgac cactacgatc tttggttttc ttatccggta ggttttcatt ttcacgaccg
    39481 gttcaccgtc tctttccttt tatccttgtc ccgatgtgtc acattgactt tatagttttt
    39541 ccctaaagca tttgccaaac gttcagtcaa tgccacagaa cggtgttgac cgcctgtaca
    39601 gccgattgca actgtcaagc tgctttttcc ttctttaatg tatccaggca atacagtttc
    39661 cagaagatcc aaaaatttat ggtagaatga ttgcgtttca tcaaaggaca tcacataatc
    39721 atagactggc tgatcttttc cggtcaatgg tcttagttcc gggatataat gagggttggg
    39781 caaaaaacgc acatccatca caatatccga atcgatcggc aacccgtatt taaaaccaaa
    39841 tgatacaaat tcgatccgaa atccttggtc tccctttgat ttgaatgact cattgatttt
    39901 ttcacgtaat tgtcgtggtg tcaatgtcgt cgtatcaatg atcacggaag cttgggcttt
    39961 caagtcgtct agtatcgccc gttctttacg tatcccttca gtgatcaaac cgtccatcgc
    40021 cattggatgt gctcgtcttg tttctttgta gcgagccact agttcttcgt ctgaagcatc
    40081 taaaaataag atagaagtgt cgatgaagtt cgtattttcg atttcgatca gcatgttttg
    40141 gatttcttca aagaaggaac gagaacgtaa atccactcct aaagccattt ttgtgacttt
    40201 gcctgattct ttgattaatt cccagaattt tggaatcaat cgaggcggca tattatcgat
    40261 acaaaaatag cccatatctt caaaactttg gatagctact gttttccctg caccgctcat
    40321 acctgttatg atgactaatt gcaaattatc tgtcataatt acgaactcct ctcacattgt
    40381 gcatagtaaa attatatcat tccgggcgta tcattaccag ttttcttttt cttttacaaa
    40441 aagatttgga ccaaatatct tttaggatat ttgccccaaa tccaattttt ttacttttcc
    40501 gatgctgtat ccaatgcctt gcttctttca gctagcgctc gttcaatcgt ccgatctgct
    40561 aaaatagatt gggcatcgat cactggataa tggttatctt cagcaaattc atgcatcaat
    40621 gacaattctg tgcaacctaa gataactttt tcacagttta ggcgctctac cgcttcttct
    40681 aagatttcgt aatatagctc ttgattcaaa taatccgatt ccttgatctc atgatagatc
    40741 agataattga ttttttcttg aagaacagta tcaggaatca ctgtttcgaa tccaagattt
    40801 ttgacttcgc gttcatagat tccagctttc atacttcctt ctgttcctag aatcgctact
    40861 ctccctgtcg tatgctgacg gacaagttca tttgctgctt ctcttggcat atgaaggata
    40921 ggaatatccg ttgccgcttg taattcttca aaaaagtagt gtgcggtgtt acaagtcaac
    40981 acaatgaagt tcggctgcaa taaattttgt ttctcaatat catccagcag aaacggcatt
    41041 ggattttctt ctgatcgatc taaaatataa gctgtacgat caggaactgt tgcatgattg
    41101 aataagacat aattcaaata ttcttgatct tttgtagctt tcgttcggtg gttgatcaag
    41161 cgaacaaaac tttctgtcgc catcgtgccc attccgccta aaatactgaa aaaattctcc
    41221 atgaactagc cttctttcac atgaaaatac tttttgaatc ttggaatata gttatggaac
    41281 atatatttca tcaacaacca gcgcttgatt gaccggtctt tttcataaaa cacagtagta
    41341 ccgtaacgat tttctttgat catttgctca gctagttttt tgtcttcatt ttcccgagca
    41401 tattctaaaa agattttttt gggcacaccc atccataatc ttgctttatc tgattgattc
    41461 gttccatagg tcgtttcaac aaagggtttg ttaaacactc gatcttctgt gacgaaacga
    41521 gccagattca agccgttcaa tgtcacaaag aaactgctac gaccttgtct caaattgatt
    41581 tcaaataatt tatattctcc atctctagga tcatacttca tatcgaaatt ggcaaagcct
    41641 gtatattcga ttttttccaa aaatgcctta atggtttgat agattttttc gttataatct
    41701 ggcatgatca caacgtaatt accaatcgat gctggtgtag gatcttctaa cagtggatga
    41761 ccaagacaca tcatccgaac ttgatgatct tcatctacat acgcatttag cacacgcata
    41821 ttactatcat cacccgggat aaaatcttgt acaatcattt cacttttata accggcttcg
    41881 tatatccggc ctaaaattaa atcgaactct tctctagtct ctaaaataaa agcttttttt
    41941 cttccttcaa attggacaga aagatactcc acactgtttg caggtttcaa agcaactggg
    42001 aattcaaaag gcaattcctg ttccaaatgt ccatttacta acatttcttc tctgacgatc
    42061 aatgttttag gatacggaag atcatattct tcacaaactt cataaaagct tactttattg
    42121 atcagtcttt caaataaaga ataatcaata tatggacaga taaaatattc tgacagctct
    42181 tgtttatgtt gggagatcaa ttctgcatat ccatcaccac aagcaatcaa aagatatttt
    42241 ttactcttat cagaatatct ttcttttgcc aaacgaagca tcgtctcgat aaacacaggg
    42301 tctttatcaa atcctggaat aacttctaca ttgacaattt tactgtagcg ggtaggggct
    42361 aactgatccg aagcatatgc ttggcagatt ttgccgtatg cttcattaaa agaacgtgcc
    42421 ataccataaa cgttcatgtc gcttcctaat aatataggga taaattcttc attttcaata
    42481 ctgttcatca ttatctctca cttactcata atctcttgtt tttcttttcc aactacacaa
    42541 ggaatatcat accataaaga aaaaagcaat caaaggaaac tcctccgatt gctcaattct
    42601 tttttgaacg gattgaactt ataggaagtt tttgtctata ccaatcagtg tagaaagaac
    42661 taccatgtaa tgattctaga acactgatat taataaaaca agcaaaaatt cattttttta
    42721 tgttttttta actatctcag ctatctatcc tctttatacc attatttttt tcaaatagtg
    42781 acctgtataa ctttctttta cgttaatgat ttcttctggt gttccagtcg caaggatcgt
    42841 tcctccacct tctccacctt ctggtcctaa atcaatgata taatctgctg ttttgattac
    42901 atctagattg tgttcaatca ctaaaactgt gttaccagca tctactaatc tttgtaatac
    42961 atgcaacaag cgggcgatgt catcgctatg aagtcctgtc gttggttcat ctagtatata
    43021 gaaattcttt ccattagaga ttttgtgcaa ttcactggca agtttcatcc gttgtgcctc
    43081 accaccggac aatgtcgttg ctggttgccc catcgtcaca taacctaagc caacatcaac
    43141 aatcgtttgc agtttgcgat gaatctttgg aatgtgcttg aagaattcta cagcatcttc
    43201 tactgtcatt tccaaaatat cagcaatgct ttttcctttg taatgcactt ctaatgtttc
    43261 agagttatat cgtttgccat gacatacttc acaaggaaca tagacatcag gcaaaaagtg
    43321 catttcgatc ttaataattc catccccgcg acaagcttca caacgaccgc cttttacgtt
    43381 gaaactaaaa cgccctttct tataaccccg catttttgcc tcgttcgttt gagcaaataa
    43441 cccacggata tcatcaaata cacttgtata agtcgctgga ttacttctcg gcgtccggcc
    43501 gattgggctt tgatcgatat cgatgatctt ttcgatactt tcgtagccgg aaattgtctt
    43561 gaatttacct ggcttagcag aattcttatt taatttttgc gctaacgatt tctttaagat
    43621 actattgacc aatgtactct ttccagaacc agacacacct gtgactgcta caaattctcc
    43681 taatggaaat tcaacactaa tatttttcag attgttttct gaagcaccag tgatcttgat
    43741 tgctttccca ttacctttac ggcgttcttt tggtacaggg attgattttt tccctgaaag
    43801 atatttccct gtcaaagaat tttcatcatt agctacttct tcaggagtgc ctgcagccac
    43861 gatttgtccg ccttgttctc cggccccagg tccgacgtca atcagataat ctgctgccca
    43921 catcgtatct tcatcatgtt cgactacaac gagggtgttg ccaagatcac gcattttctt
    43981 taatgagcca atcagtcgat cgttgtcgcg ttgatgcaat ccgatcgatg gttcatctaa
    44041 aatatacaaa actccagaaa gattcgatcc aatttgtgta gccaatctga ttcgctgcgc
    44101 ttctccccca gataatgttc cggaagcgcg actcaaagtt agatagtcta gtcccacatt
    44161 ttccaagaat gaaagtctgt catttacttc ttttaaaatc ggtttggcaa ttactttctc
    44221 ttgttcagat aacgttaagt ttgagaagaa atctactgct ttttgaatag acaactcatt
    44281 tgtttgcccg atattcgttc cattgatttg aacagataga gcttggggat tcaatcgata
    44341 acctttacat gtctgacaag ttaattctgt catataaaga cgcatttgct cacgcgtgaa
    44401 atcactgttc gtatcatgat aacgacgctc gatattcttc aatacccctt cgaaagtcgt
    44461 ttctacatcg cgaacgccac caaaatcatt ttcataatgg aaatggaaaa gatcatctgt
    44521 cccattcaag atgatatcct gatgctcttc cggtaattct tcgaatggtg tatctaaatc
    44581 gataccgaaa ctttcacaag cctgcgctaa catttgagga taatactgag agctgattgg
    44641 attccatgga acgatagcac cttgactaag tgtcttcgtt ctatctggaa tcactaaatc
    44701 ttgatcgact tctaatttga cacctaaacc atcacagtct ggacaagctc caaaaggcgc
    44761 attgaatgag aacagtcttg gttctagttc gccaacagta aatccgcaat aaggacaggc
    44821 atagtgttcg ctaaacaaca tttcttcttc accgatcacg tcaaccagag catagccgtc
    44881 tgccaatcgc agagccgcct ctaaagaatc aaatagacga gaacgaatcc cttctttcac
    44941 aatgatccgg tcgatgacga tcgcgatatc atgttttttg tttttctcca gctcaggcac
    45001 ttcacttaaa tcatagatct caccatcgac tcgaacgcgg acgtatccct ctttttggat
    45061 tcgttcgaat atttttttat gttgtccttt tttctttacc acgatcggtg ccaacacttg
    45121 gatctttgtg cgctcaggca aagccattac ttgatctgcc atttgatcta ctgattgact
    45181 ggtaatctcg atatgatcgt tgggacaaat cggatgtcct acacgtgcaa acaacaagcg
    45241 taaatagtca ttgatttccg tcacagtacc tactgtcgac cgaggatttt tacttgttgt
    45301 tttctgatca atagaaatcg ccggactcaa tccgtcgatg ctatctacgt ccggcttatc
    45361 catttgtcct aaaaactgac gagcataagc agaaaggctc tctacgtatc tccgctgccc
    45421 ttcagcgtac agcgtatcaa atgctaggga actttttcca gaaccggaca aacctgtaac
    45481 gaccacgaat ttatctcgtg gaatcgttac atctatattt ttcaagttat gggcacgtgc
    45541 accgtgaatc gtaattttat cgttagccat gttgtcctcc tactttgaag cttttaattc
    45601 taaaatcata tctcgcacat tagcggctgt ttcaaaatcc aatgctttcg ccgcattttt
    45661 catttctttt tctaatttca tcaataacgt atctttttct tctttcgtca tttcttcata
    45721 cgagacttgt accgcttctt ttgtatcatc ttccgattct ttcgtaatag aaatcaaatc
    45781 tcggatttct ttaatgatcg tttttggaac gatcccatgt tcttcattgt acttctgctg
    45841 aatcgtacgg cgtcttgatg tttcatccat cgctagacgc atagaatctg ttactttgtc
    45901 tgcgtacatg attactttac cttcttcatt ccgagcagct cgtccaatcg tttggactaa
    45961 ggaacgttca ctacgtaaaa agccttcttt atccgcatcc aagatagcaa caagggaaac
    46021 ttcaggtacg tctaatcctt cacgaagcaa attgattcca actaacacat caaattcacc
    46081 taatcgaaga tctcgaatga tttctgttcg ttccagcgtt ttgatatcac tatgcaaata
    46141 tttgactttg atccctaatt ctttgaaata atctgtgagg tcttctgcca tttttttcgt
    46201 caatgtcgtt acaaacaccc gctggtcttt ttcgactcgt tcatttattt cgcctactag
    46261 atcatcgatt tgtcccatga ttggacgaac ttcgatcact gggtcaagca gccctgtcgg
    46321 acggatgatt tgttggataa cggtatctgt ttgttcatgt tcatatggtc ctggcgtcgc
    46381 agagacataa atgatctgat tgacatgttt ttcaaactct tctaaccgaa gtggccgatt
    46441 gtctaaagca gatggcaaac ggaaaccgta atctactagc atctgttttc tcgctcggtc
    46501 accattatac attcctctga cttgaggcat ggttacgtgc gattcgtccg ccacgatcaa
    46561 aaaatcttca ggaaagaaat ccaatagcgt ataaggcggt tcaccttctt tacgtccgtc
    46621 catatgccga gaataatttt caattcccga cgtgtagccc atttctaaca tcatttcaat
    46681 atcgtaattg gttcgctgtt ctaaacgttg agcttccaga agtttgtttt catttcgcaa
    46741 gacagttaaa cgctgttcta attccgcttt gatattcgct acggcatgct ccatatgttc
    46801 atcattcgtc acaaagtgag tcgccgggaa gattgccacg tgttccgttt ctcctaaaac
    46861 ttcacctgtc agtgcattga cttctcggat acgttcgacc tcatctccaa aaaactccac
    46921 acgtaaggca cgttcatctc ttgaagccgg aaaaatctcc acgacatcac cgcgcactcg
    46981 aaaacgaccg cgctgaaaat ctatatcatt tctttcgaat tggatactga ctaagtcacg
    47041 aatcaactga ttgcgatcta gttctgctcc ctgtcgaatc gaaactactt gtttttggta
    47101 ctcaaaaggc gaacctaatc caaaaataca tgaaacggat gcaatgacga tcacatcatt
    47161 tctttctaat aatgaactag tagccgaatg tcgtaatttg tcgatctcat catttacact
    47221 tgaatctttt tcgatatacg tatcgcttga aggcacataa gcttcaggct gataataatc
    47281 ataataagaa acaaaatatt caacagcatt gttagggaaa aattccttga attccccgta
    47341 cagctgacca gccaatgttt tgttatgggc aataattagt gttggtttat tcactttctc
    47401 aataagattg gaaatcgtat atgttttccc tgttccagtc gcacctaata agatttgtgc
    47461 ttttttcccg ccgactacgc catccactaa ttggttaatc gcttcaggct gatcaccagc
    47521 cggttggtat ttcgagacaa gctcaaagtg tcgggaggta tctctctcaa tcattcttcg
    47581 tcctcctttt cattcattcc ttttcatttt acgaccaata aaaagaaaag gaaagcaaag
    47641 gcattcctta ctaaaaaatt ataccaaacc gaacatactt tcgccacttt tttatcttat
    47701 tatgcatgtt acgttttata acataaaatg ttagaaactc gcattttttt cattttttcg
    47761 agcttacagt cttgtctgat tcagcacttt tcgcctataa taataaaata ttggaaattt
    47821 aggaggttga ttatgaaaag aaagcattta tttcactcat ttgttttctt aatgacagga
    47881 cttgtgacac ttgcgtttgg acatgttgca caagctgaca acactacaac ggcagagtca
    47941 agcacaagcg agacaatgca aaaaatagag cccaaaaaag acgtatacgt aattgccagt
    48001 gactctgctt ttgctccatt tgaatttcaa aacgcaaagg gcgagtacga aggcatcgat
    48061 gtaaaattga tggaaaacat cgccaaactg caaggattta acatccgaat ggactaccgt
    48121 ggtttctctg ctgctttgca agctttggaa tcaggacaag cagacggaat gattgccgga
    48181 atgactgtaa cagatgaacg aaagaaaagc tatgattttt ctgattctta ctttgatagc
    48241 gggatccaat tagctgtcaa aaaaggagat acttcgatca agtcttatga agatttgaaa
    48301 ggaaaaacag tcggagcaaa agttggtacc gaaagtgctg aatttttaag cgaccatgaa
    48361 tctgaatatg gctattctat caaatatttt gatgctgctg atcaattgta cgacgggtta
    48421 aaagttggcg caatcgatgc aatgatggat gattatccgg taatcggtta tgcgatcaaa
    48481 caaggacaag aattggaaac accgatcaaa aaagaatctg gcggaaaata tgcatttgcc
    48541 gttaaaaaag gacaaaatcc tgagcttctt aatatgttca atgaaggatt gaaagaatta
    48601 aaaagaacag gcgaatacga taagattatt aaagaatatg tagcggatgg ttcagaaact
    48661 tccagtgagt cttccactgc tgatgaatca acatttcttg gacttatcca aaacaactat
    48721 caagcattgt tgaaaggact ttggagaaca attctcctaa ctttgatctc ctttgctttg
    48781 gctatagtaa tcggtgtgat ttttggatta ttcagtgtag caccaatacg cgctcttcgc
    48841 acaattgcta gtatttatgt cgatatcatc cgaggaattc caatgatggt tcttgcgttc
    48901 tttattttct ttgggttgcc tggtatcgtt ggatttacga ttcctgactt ccttgctggt
    48961 gttatcacct tgactcttaa cgcaagtgct tatatcgcag agattgttcg aggcgggatc
    49021 aacgccgttc ctgtcggaca aatggaagct tccagaagtt taggtctttc ttataatcgg
    49081 acaatgcaaa aaatcatttt gccgcaagcg atacgcatca tgatcccatc attcgtcaat
    49141 cagttcgtta tctcattaaa agacacaacg atcatttccg caatcggtgt agtcgaattg
    49201 ctgcaaactg gtaagatcat tgttgcacgt acaacacaaa gtacgtatgt ttacttgatc
    49261 attgcgatca tgtacttgat tttgatcaca gcattgacaa aattagcaaa agttttagaa
    49321 aagaaggtga agtaagatgg cagaaaaaat cttagttgag catttagtca aaaaatacgg
    49381 cgataacaca gtattaaacg acatcaatgt gtccatcaac gaaggagatg tcgtctgtat
    49441 cattggccct tcaggttcag gaaaaagtac atttttgcgt tgcttgaatc gtttagaaga
    49501 accttctgac ggtgaaatta ttattgacgg cgcccacttg atggataaaa gcacagatat
    49561 caacttggtg agacaacata tcggaatggt attccagcac tttaacctat tccctcatct
    49621 ttctattttg gaaaacatca ttttagcacc gatggacctg aagaaagaat ctagagaaga
    49681 agcagagaaa aaagcaatca aattgctgca gacagttggt ctagaagata aaaaagatat
    49741 gtatcctgaa atgctttccg gtggacaaaa gcagcgtgtg gctattgctc gtgctctagc
    49801 gatgaaccct gacatcatgc tttttgatga gcctacatct gcactcgacc ccgaaatggt
    49861 cggtgatgtc ttgaacgtca tgaaaaagtt agcagaacaa ggtatgacga tggttatcgt
    49921 tacgcacgaa atgggcttcg ctaaagaagt ggccaatcgt gtcatgttca ttgacgacgg
    49981 aaacttttta gaagacggaa cgcctcaaca aatctttgaa aatccgcaaa atgaacggac
    50041 aaaagatttc ttgaataaag tattaaatat ttaataaaaa ccaaaaatgc ccggtcgctt
    50101 catgacgacc gggcattttt agtttcttgt tttttcactt aactgtacca gccgcatcgc
    50161 ttgttctcct gcacaaacaa gcaatcgctc tacctgttcc atcgcataag aaagtaccat
    50221 cggttcattg acgatatcaa gtacatagtc gataccacct tcagaaacta tgatgattat
    50281 cttattctaa agctggcttt tttgttggta caaacatgac aactacaaaa aaaccaggcg
    50341 aacgtatgat tgttcgtctg gtttttaatt attaatgact tagcgttttt actagaaata
    50401 gaaaatttgg gcaagtctac tttatatttt tactagaaaa actacttccg ctttttcccg
    50461 ccaaaagcat ctttaaactt atcgaagaaa ccgtcttctt gctgttcttc aactttgatg
    50521 ccgccagctt cagcgaatgc acgtaatgct tctctttgtt gttcatttag atttttcggt
    50581 gtgatcagtt ttactttgac atgttggtcg cctgttgcac caccacgtaa cttcggagcg
    50641 ccttttccac gtaaacggaa gttcgtacct gtctgtgttc cagcagggat cttcaatttc
    50701 acatctccat ggacagttgg tacttggact tcatccccca aagctgcttg tacaaaactt
    50761 aaaggcaatt catagtaaat ttcagaacct tcacgatcaa agatatcact ttcttctaca
    50821 cgaaaaacca catacaaatc accaaatggt ccgccgtttt ctccagcttc tccttgacca
    50881 gctaaacgca tttgttgtcc ttcttctaca ccagctggta cattcacttt aactgaatgt
    50941 gctttcttct catgtcctga gccatgacag gttggacaag gttctttgat ttctttccct
    51001 gtgccatgac aaacatcaca agtttgacgg ctcatcactc gtccaagtgg cgtttggcgt
    51061 tctacattga tcgtacctgc accatgacat ttatgacaag tagttggttg tgtgcctggt
    51121 tttgcaccgt ttccaccaca agtatgacag atttcttccc gattatactt gatttctttt
    51181 tctacaccaa aaatcgcttc ttcaaaagac aagtcgaccg tatattgcaa atcagcacct
    51241 tgacgaggcg catttggatc gactgaccga ccgcctcctc caaagaaaga gtcgaagata
    51301 tcttcaaaac caccgaagcc gccaccagag aagccgccga atccaccaaa tccgccacca
    51361 gctccaccag caccgtaatt tggatctgtg cctgcatgcc cgtattggtc gtatgcagcg
    51421 cgtttttgcg ggtcacttaa aatctcatat gcttctgata cttctttgaa tttttcttcc
    51481 gcatcaggtt ctttattgat gtcaggatgg tattttttcg aaagcttacg ataagctttc
    51541 tttatttcat cttctgatgc tccttttgag agccctaaga cttcataata atcacgtttt
    51601 gttgccatag gctttcctcc tattggttct catcattttc acgtcgcttg ttatcatatc
    51661 atattttgtt tgaaacaaaa accgatactt caaactattt ttcaaaagaa aaagccaaag
    51721 tagcaacttt ggccttctct cgaaattcag tgaactgatt atttatcgtc gccatcgact
    51781 tcttcaaaat cagcatcaac gacatcatct gctccgcctt gagctgcttc tggattttct
    51841 tgagcttgtt gttgtgcagc ttgttcgtat agtttaacag tcaagttttg aacgatttcg
    51901 ttcaatgcat cgcgtttagt tttcatttcc tcgatgttgt ttgcttcaac agcggctttt
    51961 aattcgtcac gagctgtttc tgcttttttc acttcttctt cgtccacttt gccttctaat
    52021 tctttcaatg ttttgtccac agagaatagc aatgcgtcta catcattacg taggtcaact
    52081 tcctctttac gagctttatc tgcttcagcg tttgcttctg catctttcac catacgttcg
    52141 atttcttcgt ctgttagacc tgaagaagat ttgatcgtga ttttttgttc tttttgtgta
    52201 cctagatctt tcgcagatac atttacaatc ccgtttttat caatatcgaa tgttacttcg
    52261 atttgtggaa taccacgagg agctgctgga atatctgtca attggaatct tcctagagtt
    52321 ttgttgtcag cagccattgg gcgttcacct tgtaatacat ggatgtctac tgctggttga
    52381 ttatctgccg cagttgagaa tacttgtgat ttacttgttg gaatcgttgt attgcggtca
    52441 atcaatttag tgaacactcc acccattgtt tcgataccta atgacaatgg tgtaacgtca
    52501 agtaaaacaa catctttcac atcaccagtg atcacgccac cttggatagc agcacccata
    52561 gcaactactt catcagggtt aactgatttg tttggttctt ttcctgtttc tttacgtact
    52621 gcttctacaa ctgcagggat acgagtagat ccaccgacta aaataacttc gtcgatttct
    52681 gattgtgaca gacctgcatc ttttaacgct tgacgtactg gtacttttgt acgttctact
    52741 aagtcagctg ttaattcatc aaattttgca cgtgtcaatg tcatttccaa atgcaatggt
    52801 ccagattctc ctgctgtgat aaatggcaag ctgatttgtg tgcttgatac gccagataaa
    52861 tcttttttcg ctttttcagc agcgtctttc aagcgttgta aagccatttt gtcttgagac
    52921 aagtcaatgc tgttttcttt tttgaattct gctaccatgt agtcgatgat tttgttatca
    52981 aagtcgtccc cacctagatg gttgtcgcca gctgttgaca atacatcaaa gacaccgtct
    53041 cctagttcaa ggatagatac gtcaaaagta ccgccaccaa ggtcgaatac taagattttt
    53101 tcgtcgcgat ctgttttatc taaaccatag gcaagagcag ctgcagttgg ttcattgacg
    53161 atacgttcta cttctagacc agcgatctta ccagcatctt ttgttgcttg acgttgtgca
    53221 tcattaaagt aagctggcac agtgataact gctttttcga ctttttcacc taaatagtct
    53281 tctgcgaatc ctttgatata ttgaaggatc attgctgaga tttcttgtgg tgtatatgat
    53341 ttaccttcta catctacttt gtaacctgct tcaccgatat ggcgtttgat tgatgaaatc
    53401 gtatttgggt ttgtcacagc ttgacgtttt gcaacttccc ctacttggat ttctccattt
    53461 ttgaatgata caacagaagg tgttgtacgg tttccttctg ggttagcgat gatttttgct
    53521 tcgtttcctt ccaatactgc tactgcagag ttagtcgtac ctaagtcaat accgataatt
    53581 ttactcataa ttaacgtctc cttctttaat tgaaagtgta agttttatat ccgcacaatt
    53641 attgtgcaac aatgaccata gttggtctta acacgcgatc atgtaatttg tagccttctt
    53701 gtagtacttc tacaatcgta tcggctggtg tatcttcagt cgctggaaca gtttgtactg
    53761 cttgatgaag attaggatca aaggcttctc ctttagcagg gattttttca attccttctt
    53821 cttccagtgc gttacgcaaa ctttccaaga ccatttccac gccttttttc aaacctgccc
    53881 cttgatcatc tgacacttct gtggctaatg cacgttccag gttgtcaatt gatggaagta
    53941 attttttggc taaatcttgt gaacggtatt tttgtaattg ctcacgctca ttttttcctc
    54001 gatttgccat atttgcgatt tcagcacgag cccgcaagta tttatcttcc atttcttcta
    54061 actcagcttt taatttcgct gtttcgaatt cttccgcttc agcttctgaa atacccgaat
    54121 cttctgcagc ttcgacatcg atttccggtt ctggctgagc atctgtcatt tctttatcta
    54181 gttcttcttg attttctttc acgatacagt cttcctttca ttattcagtc agctgtttga
    54241 ttgctcttac taagaaagag agaacgatca gctgcaaata gcttcgttat tcacattacg
    54301 agtttgacaa gtcaagcgag cggtagtaat cagcaagttt agctgctagt tctcttcgat
    54361 aaacatcgac tagaccgaac atccgagaat aaggcatact agtaggccct aacaaggcta
    54421 ttgtacctct tccatgacca tctatctcgt aacttgcttg aatcatactc atattctgca
    54481 ataaatcatt gcctaattca gcaccaatct tgatatgaat attgctatcc atcggagtga
    54541 tcatttgtgt aagtccgtct gagtctttca taaaagaaaa catcgatttg aactgatcaa
    54601 gatcttgacg gggctcataa tccaagagat tcatttgtcc actgacataa accttttctt
    54661 caaaaacatg accaagaacg gtgtcaaata actgagacat cccttctgtc gtctggaaat
    54721 atttatgaag aatcatcgga atctccgtac gaagtttatg gtacaccgtc atcagaggat
    54781 ctccgactag acggtcgttt acaatctgta ccattttttc tagttcctga cttcccatat
    54841 attcgggaag agtgaacact tggctttcta cattccccat atctgttacg acgatagcaa
    54901 taatctgtcg attattcaag ggtacgatac gaaagccagt cagtcggcgg tcttttattt
    54961 caggtcccaa tgaaaaagtc gtatagcttg tcagctcaga taatatctca gcagattgct
    55021 taataatctc attgatttca tgaaattctc tgcctagaga ctgacgaatc agcagcaaat
    55081 catcttctgc tacgcgagca ggttttaaca aatgatccac gtaataacga tagcctaaag
    55141 cagatggaat ccgcccagaa gaagagtgag tcttcaacag caatccttca tcttctaatg
    55201 ctttcatatc attgcgaatc gttgctgagc tggccttgac tccctcagac attaatgttt
    55261 tggaaccaac gggcacgcca ctactcgtat agtgttggat gatcagacgt aaaatgtcgt
    55321 tttgtcgctt tgttaacatc ttcctcacct ctcattagca ctcatatatt ctaagtgcta
    55381 attcacttat aaatatagca agaagccctt ctcctgtcaa gagaaagact ccatttttta
    55441 gcactctaaa cacaagagtg ctaattctaa ataattgatg taaatccagt tatatcaata
    55501 cttcaatacc tcattgtcaa actttctaaa ctttttcttt tcaagtttcg ataaaaaaca
    55561 aatattcttc aaactatttt tcaaataaaa agcgctcaaa cacattgttc cccaaaaaag
    55621 tccctcttgg tgtcaaataa acacggtctt cttcattaac aagtaaccct tcttgctcta
    55681 attcccttag cacatcaccg tacaccgatt caattgtttt ttgatagcga tcatagaaat
    55741 gttttttagt aatccctgtt ttttttctta gtcctaagaa catttcttct tctatttgat
    55801 tttttcgtgt caatttttct tcttccaata ccgggcgttc atttgctcgt aatgggcgta
    55861 aatagtgttg gattggtcct ttgttgcggt aacgaatatc tccaagataa ccgctagcac
    55921 cagctccaaa cccaaaatag tggtcattgt tccagtacat gaggttatgt tgagattcat
    55981 gtccggagag cccaaagtta cttatttcat attggtgacg tccatgcttt tccattgctt
    56041 caatcgtctc ttcaaacatt ctggtttccg tttcctgatc aggcagttcg agtcttcctt
    56101 gtcgtaccca gttcatgaac attgttttgt tttcgaggat caatgagtac aaagaatagt
    56161 gaggcagatc caaagccaaa gctttttcca aagtatcccg atatccttct agtgtttgtc
    56221 ccggtaatgc ataaatcaaa tcgatgctta cattggtaaa attttctgct tctaaaaatt
    56281 gcattgtttg atacacatct tctgcagtat gtttacgtcc aatttttttc aataagcgat
    56341 tgtcaaatgt ctgcactccc atggataaac gattgacgcc atagtttttc atcacttgaa
    56401 gtttttcacg ggtcaaatca ccaggattcg cttctacagt aaactcatta ccattttgaa
    56461 aaggcaggat ctctctagca cctgataata gtcgatcaag ttgtttagca gataaagaag
    56521 ttggtgttcc gcctcctaca taaagtgttt ccaaattcgc tgtaggatga ctttccagca
    56581 ttaatctcat ttcattcagc agcatttcca catactcatc tactggctgc ccttctaaaa
    56641 aaactttatt aaagtcacag taatagcaga tatgctcgca aaatgggata tgaatgtacg
    56701 cagaaacctt gttttctgcg ggatttattg tttctatcat tgaaattctt tctccttacg
    56761 tcgaaaagtc gtgcctgttt tcgaccttct taaaatcgcg ttcaagcacc aactcattga
    56821 aataagccgc atatttagaa tcaaggaaac ctagctctaa aaatgcttgc ttattgtcat
    56881 cggagctaca cggtgctttt acagcctctc gataaacggt aatcgcaaag ctgaccttcg
    56941 gcattaagtc aaaatctgca aaaatatgaa aagctatttt cacagattcc tccttaagtg
    57001 ctcagaccac aacgctttgc ttacaacctc tcatatacgc atactaaacg tatttggcga
    57061 acaaatccac taaaaaatcc aagaatcgac ttcttggatg atttttttac actcatgatt
    57121 cttcctaaac aattttgtcc ttattttatt cataaaaaaa tctagtcaaa tctctcactt
    57181 caagagtttt aactagattc caattattat ttttttgtaa aaataaacag tctcttaatc
    57241 atagacattt cttcggtgcc ctacttgaat agcgataaca acgaattgat tatcttctat
    57301 ctctaccaat acacgtattt gccaatcaga gctgcttctg aatttcgggc gtgaatttta
    57361 aacggcaggt cattccagcc caccaaattc attaaggatt cttccatgaa tactgttgtt
    57421 ttcccacttc ttatccaatg tttatgggca atttcagccg tttgacgatt gtattcatct
    57481 tctagttgtt ccatcgaata gttttttaga agttcagata aagtaatccc ataaaattca
    57541 gccatataag aaagccattc ttttttggcg tcacttacac gaaccgtaat catagcccta
    57601 taattgcctc tcttaaagaa tctcatgcat ttcctgatgt gattttagaa aaatttactt
    57661 gctaaaaaac tgtgaaaatg taggagctag catccttgta gtaaatgatc gagctcttta
    57721 ttatacatta aaaaagttca gaaattttga tgaagtagcc aactactttt tcatgagtaa
    57781 agcaacacta gaaaaagaat cctccagtac ttagaattta ctggaggatg tacttttgaa
    57841 gaagcctata ggttatttaa aaaatattac tacaggaagg aacgagaatt acttcgttac
    57901 ttataataga acttagtctt atatagaagg catagctcac attagcttat ttgtcctata
    57961 aaaataaatt acggtatttt agaaaagcta ttttctcttt tttcaacgat cttcagcaat
    58021 ttttctttat cgtcaggtaa ctcaagttca tgaattctag catgacaatt gggacataac
    58081 gcgatacagt tttcaatcac atcttttcca ccttgcgaca aatattctat atgatgacaa
    58141 tgtaaataag gtacaccgtc ttttataaat ggcccttttt cttggcaaag ttgacaaata
    58201 ccttttgcaa gtcgtttaac atattcagat acgaagggat tacgtttata tatttttgtt
    58261 tttgagaagc aaaactcctc ttcgttaaca tattttgcag ccattttttt attataatta
    58321 ctaacttttc ttgcttcttc ctctaattta gcattagata aattacgaat atgtctagtt
    58381 tgattttctt cctggttata tatctttatc ttcaatcaat tgctcttgat ttattaaagc
    58441 taatggaaat ttatatactt ttctgctgtt gcccgaacta tctttttcat taacagtata
    58501 tatttgtcct gctaaatata cttctcccag atatgtgtgt tcttttggtt taaatgtttc
    58561 aaataaatga atctttacaa aattactttt tgaattggct aaaactttat tttgattctt
    58621 atccaatact tgatcccctt ttagccccat accggtatat tgtaaaatac catttaacca
    58681 cttatcttta taaacattac ttcctgtttg atcactaaac agtacaagag tattagtttg
    58741 atgagatctt ctcattccac cctgtttgga acatttaaac ttctctgaaa tttctttgtt
    58801 agtatatact ctaccaactt ctaactcacc taatatgttt ttagaccaat tttctcgcca
    58861 tgtaataatc ttatcaagat taaacatttc tccctctttt ggcatgccat ttctaattaa
    58921 attagctaat acaccagtag aaatatctaa tttttttagt aattctttct tagtaatcaa
    58981 tgttggattc ataacaatgc agctcctaat gatatcaata taattgcatt agataacttg
    59041 aaaaatcgaa aaaaactcat tttgtgtcaa gttatctgta atatataaaa atatcattat
    59101 tatacctcat ctatgtgaat ttttactatt cttaccttag catattcttt ataggtatat
    59161 cagagctaat caaactaaaa aatacccgaa gtcttcttat gtaaaaacac cggttattac
    59221 ttaaatatga cttaggtaaa acaatgagtg atccaattat aaaattttat ggcgaataat
    59281 ttagtaagcg ctacatattg aatgatttag aaattttgaa aaagtagcta gttcctttta
    59341 taccagaaaa gtaaacctaa taaaaaacac aactaatttt tagctgtgtt ttttaagtta
    59401 caataattat ctatttaata gtcttaattc attaaaataa aaaactcaac tttacaagga
    59461 tatggtttaa aaaatttatt tatccaaccc aactagtttt cgctgcttac gatttgcttc
    59521 atctgctacg taattcatta ctgttttaaa ttctttcgct gaggcgtttt ctgataaatc
    59581 agcgatactt ttattatact tcttcacgat ttgttgtact tgttctttct cagtcatgta
    59641 attcctcctc caactctttt gaagtatatt gtattggtag tactaattga atattatctg
    59701 ctgcataatg cacttcagaa atgtcgtttt gataatcctt aatcattatg tgaaggacta
    59761 cttcaggatg tctatttttg actttttcaa tattctctct ggacttaaaa aacgcattga
    59821 taaacatttc ttttggcaca tgacgtcctt cagctagttc acgttttcga gtgaaatccc
    59881 aggcaacttt gggatcttgg taaacataga aaatcgtaac gcgaaagtta tttttaaggg
    59941 ctcgaataat atttttctct gcactaagga tagcaaaagt atcctctagt atgaaagaat
    60001 agccatgttc cagtacatat tttaatgatt gttcaactaa ccaagaagaa gctttctgaa
    60061 aaacacttga gttctttcca ttgtattctg gaaattgtgc tctaaaatag tccgcatcaa
    60121 tcacaacatg gttgtcataa ttttaagcta aacctagtgc aacctctgtt ttacctgctc
    60181 ctgggcttcc agccatgaat accgcatctt tttcatcatc agggattttt cccttgatga
    60241 ttgtttcaat aaatttatct ttattgaccc tagcgtaatc taaatacttg tctttaggtt
    60301 ccaagattgc accttctttc cttcttctat attcatacta attatacgat atttatataa
    60361 aaaatataac ggtcatttta accatattaa catttagtca cagtaatagc agatatgctc
    60421 gcaaaatgag atatgaatgt acgcagaatc cttgttttct acggcattcg cttttttttc
    60481 attggactag ttatatattt ctagggttgt tttcatgtct gagtgcccga tatgatttat
    60541 ttttcgtttc tataattact ttttgccttc cagtttcttt taagattgta ctcaagcaag
    60601 tgggaattgg ttcttttgtc atccatgtat gcaaaatgtt ataatgctgg taaacaaaaa
    60661 tgattacctg tcatttttat ttagttcgta tttaattaag ttgactgtct gtatactctg
    60721 tctaaaactt aagaattgtt gttttcgctg tcgctatcca aatttaatga atgtctgtat
    60781 gttaaaactg ttgtccttgt catagatagt aaaggagagc ttgaaaatga aaactgcgat
    60841 tacgtttcta ttagaggaat atgccgattg ggaaggtgct tatattacta gcacactaaa
    60901 ccaaaaagag ggatggcaaa acaaaactgc ttctatccaa tcagaggtca cttccattgg
    60961 aggattaaaa acaaaaatcg attacttaat cgaacaaata cctgaaaaag ttgacctttt
    61021 tattatgatc ggtggcaatt catgggacat aaaaaatcat catttatatc aaataatcga
    61081 taaattgtta aaaacagacg taccagtagc tgctatttgt ggggcagttg attatttagc
    61141 tcagagcgga ttattgcaag gttacaaaca caccggaaat gcgcaatttc cttggttaga
    61201 atcggaaaat tatcagaata aagaagattt tatagaacaa caagctgtga aagatcgtaa
    61261 tttgattact gcgaatggaa cagctcctat agaattcaca gacttgattc ttcaagcagt
    61321 ccattttgaa acagaagaaa taagagaaaa aaagattcgt ctatacaaac ttggattcta
    61381 tgattactat aaaaagtacg gagatccttt ctcctaatca ttctcttcaa ttaaatactc
    61441 catatcaata gtatgacaag taattttact gatggttatt tgtcacactt tttctgacat
    61501 ttatcaaaga agatacactc tatttatatt cata
//
LOCUS       DAMEEU010000006        60916 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.006, whole genome shotgun sequence.
ACCESSION   DAMEEU010000006 DAMEEU010000000
VERSION     DAMEEU010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 60916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60916
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.006"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(151..2304)
                     /locus_tag="PB779_000402"
     CDS             complement(151..2304)
                     /locus_tag="PB779_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HDE0737949.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
     gene            complement(2598..3446)
                     /locus_tag="PB779_000403"
     CDS             complement(2598..3446)
                     /locus_tag="PB779_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDE0737950.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="PB779_000404"
     CDS             complement(3670..5610)
                     /gene="thrS"
                     /locus_tag="PB779_000404"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HDE0737951.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            complement(5947..6126)
                     /locus_tag="PB779_000405"
     CDS             complement(5947..6126)
                     /locus_tag="PB779_000405"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HDE0737952.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="PB779_000406"
     CDS             complement(6173..7996)
                     /gene="cadA"
                     /locus_tag="PB779_000406"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDE0737953.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            8274..10553
                     /locus_tag="PB779_000407"
     CDS             8274..10553
                     /locus_tag="PB779_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0737954.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            complement(10646..11293)
                     /locus_tag="PB779_000408"
     CDS             complement(10646..11293)
                     /locus_tag="PB779_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0737955.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(11472..12191)
                     /locus_tag="PB779_000409"
     CDS             complement(11472..12191)
                     /locus_tag="PB779_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0737956.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(12322..13473)
                     /locus_tag="PB779_000410"
     CDS             complement(12322..13473)
                     /locus_tag="PB779_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HDE0737957.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(13690..14430)
                     /locus_tag="PB779_000411"
     CDS             complement(13690..14430)
                     /locus_tag="PB779_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDE0737958.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="PB779_000412"
     CDS             complement(14434..14757)
                     /gene="rsfS"
                     /locus_tag="PB779_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HDE0737959.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="PB779_000413"
     CDS             complement(14814..15407)
                     /gene="yqeK"
                     /locus_tag="PB779_000413"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HDE0737960.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(15391..16041)
                     /locus_tag="PB779_000414"
     CDS             complement(15391..16041)
                     /locus_tag="PB779_000414"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HDE0737961.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="PB779_000415"
     CDS             complement(16051..16362)
                     /gene="yhbY"
                     /locus_tag="PB779_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HDE0737962.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="PB779_000416"
     CDS             complement(16378..17487)
                     /gene="yqeH"
                     /locus_tag="PB779_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HDE0737963.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(17484..18011)
                     /locus_tag="PB779_000417"
     CDS             complement(17484..18011)
                     /locus_tag="PB779_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HDE0737964.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(18191..18976)
                     /locus_tag="PB779_000418"
     CDS             complement(18191..18976)
                     /locus_tag="PB779_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HDE0737965.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(18969..19838)
                     /locus_tag="PB779_000419"
     CDS             complement(18969..19838)
                     /locus_tag="PB779_000419"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HDE0737966.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(19839..21218)
                     /locus_tag="PB779_000420"
     CDS             complement(19839..21218)
                     /locus_tag="PB779_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HDE0737967.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="PB779_000421"
     CDS             complement(21226..21645)
                     /gene="fabZ"
                     /locus_tag="PB779_000421"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDE0737968.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(21670..22146)
                     /gene="accB"
                     /locus_tag="PB779_000422"
     CDS             complement(21670..22146)
                     /gene="accB"
                     /locus_tag="PB779_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HDE0737969.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="PB779_000423"
     CDS             complement(22149..23384)
                     /gene="fabF"
                     /locus_tag="PB779_000423"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HDE0737970.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="PB779_000424"
     CDS             complement(23403..24140)
                     /gene="fabG"
                     /locus_tag="PB779_000424"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HDE0737971.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="PB779_000425"
     CDS             complement(24152..25069)
                     /gene="fabD"
                     /locus_tag="PB779_000425"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HDE0737972.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(25176..25400)
                     /locus_tag="PB779_000426"
     CDS             complement(25176..25400)
                     /locus_tag="PB779_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDE0737973.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(25453..26415)
                     /locus_tag="PB779_000427"
     CDS             complement(25453..26415)
                     /locus_tag="PB779_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HDE0737974.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(26425..26865)
                     /locus_tag="PB779_000428"
     CDS             complement(26425..26865)
                     /locus_tag="PB779_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDE0737975.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            27171..28136
                     /locus_tag="PB779_000429"
     CDS             27171..28136
                     /locus_tag="PB779_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDE0737976.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(28193..28423)
                     /locus_tag="PB779_000430"
     CDS             complement(28193..28423)
                     /locus_tag="PB779_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HDE0737977.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(28509..29396)
                     /locus_tag="PB779_000431"
     CDS             complement(28509..29396)
                     /locus_tag="PB779_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HDE0737978.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(29485..30708)
                     /locus_tag="PB779_000432"
     CDS             complement(29485..30708)
                     /locus_tag="PB779_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDE0737979.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(30725..31771)
                     /locus_tag="PB779_000433"
     CDS             complement(30725..31771)
                     /locus_tag="PB779_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDE0737980.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIRSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
     gene            complement(31935..33662)
                     /gene="ptsP"
                     /locus_tag="PB779_000434"
     CDS             complement(31935..33662)
                     /gene="ptsP"
                     /locus_tag="PB779_000434"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HDE0737981.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDMMEEV
                     VELVHEYVK"
     gene            complement(33662..33928)
                     /locus_tag="PB779_000435"
     CDS             complement(33662..33928)
                     /locus_tag="PB779_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HDE0737982.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            34407..36641
                     /locus_tag="PB779_000436"
     CDS             34407..36641
                     /locus_tag="PB779_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0737983.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQEAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            36789..37109
                     /locus_tag="PB779_000437"
     CDS             36789..37109
                     /locus_tag="PB779_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDE0737984.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(37314..37538)
                     /locus_tag="PB779_000438"
     CDS             complement(37314..37538)
                     /locus_tag="PB779_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HDE0737985.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(37736..39316)
                     /locus_tag="PB779_000439"
     CDS             complement(37736..39316)
                     /locus_tag="PB779_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HDE0737986.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(39717..41093)
                     /locus_tag="PB779_000440"
     CDS             complement(39717..41093)
                     /locus_tag="PB779_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDE0737987.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(41221..42339)
                     /locus_tag="PB779_000441"
     CDS             complement(41221..42339)
                     /locus_tag="PB779_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDE0737988.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            42481..42915
                     /locus_tag="PB779_000442"
     CDS             42481..42915
                     /locus_tag="PB779_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0737989.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(42993..43526)
                     /locus_tag="PB779_000443"
     CDS             complement(42993..43526)
                     /locus_tag="PB779_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HDE0737990.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(43620..44798)
                     /gene="mutY"
                     /locus_tag="PB779_000444"
     CDS             complement(43620..44798)
                     /gene="mutY"
                     /locus_tag="PB779_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HDE0737991.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(44791..45588)
                     /gene="recX"
                     /locus_tag="PB779_000445"
     CDS             complement(44791..45588)
                     /gene="recX"
                     /locus_tag="PB779_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HDE0737992.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            45695..47077
                     /gene="rlmD"
                     /locus_tag="PB779_000446"
     CDS             45695..47077
                     /gene="rlmD"
                     /locus_tag="PB779_000446"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HDE0737993.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(47251..47829)
                     /locus_tag="PB779_000447"
     CDS             complement(47251..47829)
                     /locus_tag="PB779_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HDE0737994.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            48151..48621
                     /locus_tag="PB779_000448"
     CDS             48151..48621
                     /locus_tag="PB779_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HDE0737995.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(48729..49955)
                     /locus_tag="PB779_000449"
     CDS             complement(48729..49955)
                     /locus_tag="PB779_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDE0737996.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
     gene            complement(50709..50909)
                     /locus_tag="PB779_000450"
     CDS             complement(50709..50909)
                     /locus_tag="PB779_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDE0737997.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
     gene            complement(51043..51651)
                     /locus_tag="PB779_000451"
     CDS             complement(51043..51651)
                     /locus_tag="PB779_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HDE0737998.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            complement(51736..52206)
                     /locus_tag="PB779_000452"
     CDS             complement(51736..52206)
                     /locus_tag="PB779_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HDE0737999.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            complement(52254..53168)
                     /locus_tag="PB779_000453"
     CDS             complement(52254..53168)
                     /locus_tag="PB779_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDE0738000.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            53314..54117
                     /locus_tag="PB779_000454"
     CDS             53314..54117
                     /locus_tag="PB779_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HDE0738001.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            54295..55242
                     /locus_tag="PB779_000455"
     CDS             54295..55242
                     /locus_tag="PB779_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HDE0738002.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(55310..55603)
                     /locus_tag="PB779_000456"
     CDS             complement(55310..55603)
                     /locus_tag="PB779_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HDE0738003.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(55631..56296)
                     /locus_tag="PB779_000457"
     CDS             complement(55631..56296)
                     /locus_tag="PB779_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HDE0738004.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(56436..57068)
                     /locus_tag="PB779_000458"
     CDS             complement(56436..57068)
                     /locus_tag="PB779_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0738005.1"
                     /translation="MIKVLLVDDHEMVRLGVSFYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(57075..58142)
                     /locus_tag="PB779_000459"
     CDS             complement(57075..58142)
                     /locus_tag="PB779_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDE0738006.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(58139..58870)
                     /locus_tag="PB779_000460"
     CDS             complement(58139..58870)
                     /locus_tag="PB779_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HDE0738007.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(59039..59518)
                     /gene="greA"
                     /locus_tag="PB779_000461"
     CDS             complement(59039..59518)
                     /gene="greA"
                     /locus_tag="PB779_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HDE0738008.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(59654..60829)
                     /gene="mltG"
                     /locus_tag="PB779_000462"
     CDS             complement(59654..60829)
                     /gene="mltG"
                     /locus_tag="PB779_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HDE0738009.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
BASE COUNT        17496 a        12866 c        10304 g        20250 t
ORIGIN      
        1 aatttttgtc acaacctttt ttgccgagta aacggtgttc aaaagccagt ttctcggtat
       61 gaagtcaaat ttaagcaaaa atgtgagaag ctattttcac aaaatttttc ttcatactcg
      121 aaactaagcg gctttttcac gacctctttt ttattttgcc atgaacatat cataatacgc
      181 gtccattatt tctttagcaa tcgtcaagtt tatgtggtct tgttcgtcta ataagttcgg
      241 caagacaaca ctgatggcaa tttccggatt gtctgttggt ccgtatgcca cgatattact
      301 attgactgtc gcaatatctg gatgaccttc cgcaaccgtt tctgcagtcc ctgtttttgc
      361 ggaaaggtcc attttcgcac tggctaatgg tttggctgtt gtgtaaggat cggtaccatg
      421 gacaacttgg tggaatcctt cacggaggat cgccatattt tctgcagaaa tattgaccgt
      481 attttctact gttgtgccaa tttctttctt cacttcaccc aagtttccat tttcgtcatt
      541 gccatagatc gctttgacta ggtgcggctg tactcgtttc ccgccattag cgactgttga
      601 agcatattga gctaattgga ttggtgtata tgtgtcaaac tgtccaaatg ccaaatcggt
      661 aaagttacct ggagcatacc attctttgcc attatccgca ttgaacttct tcatataatc
      721 aacagaacgt gagatcccag gagattcatt cggcaaatcg atcccagtcg ttgtaccaag
      781 accaaactct ttgaaagagt ctctcaattg ctgataagct ttagcttctt catctaaact
      841 aggtagtccc attccaggtg tatagtctag tcctaacatc tttaacgcca ctttgatcat
      901 atacgtatta gaagacaatt ccgatgcttt gactgcatca agagcaactt gtccgcttcg
      961 attaaagaca gagctttttt ctgaagcacc ttgcagacga atcggctcat caatcaaaac
     1021 ttgatttccg ctgatcgcgt tacttgccca gcctgctgtc aaagtaccag ccttgactac
     1081 agaccctgga tcaaaggcgc tagtaatcgt gcctaaagca ttctcggtga tttctttgga
     1141 accttgttca tgactgaaac cagtcattgc tagcacttct cctgtctgag gattcatagc
     1201 cactgcataa gcaccaggcg aatactgtgc tttgccgttg ttgatcaatg tttgataatt
     1261 ccttttcaaa atttcttcta cttttgattg gaattctgca ttcatagata acattaaatt
     1321 agaacctttt tccccagaga agatttcttt ttgattcgaa acatttcctt cattatcaag
     1381 ggaaacttca tattgggttt tggttccttg caggacatct tcatattgtt tttccaaata
     1441 actttgtcct acacggtcat tccgagaata accttttgct aggtatttct ctgcttcatc
     1501 tgctggaagt ccttgctttt cagtcgtcac actgccaaga atacttttca gtgaacttgc
     1561 tgcattatat tctcgtgtcc agtctgtgcc agtcgaaact cctggaagtt cagaagcgcg
     1621 ttctgccaca acagctaact cttgatcagt aacaccagag tttttgatat agacagtgtt
     1681 taattcatat gcactattca tccgtttaaa gatggtagca atttttaatt gctcctcgtt
     1741 taaattaatc tcatcagctg tgactttatt gaccatcgca ctatattgtt cgctgttccc
     1801 taattgcttt tcttttgccg aaagtctttt tgtggcttct ttcaaatgtt tgggatcagc
     1861 cagccaaaaa tcttttttat ctctatctgt cagattttca tctaccggaa catcgatcag
     1921 cgagttcagc ttcgttgcga tttcaagcaa atctttagcc gtaacttgtg ttcctctcgt
     1981 atatgtgatg gcctgattcg ctttattcgt aactaaagct tttcctgtgg agtcgtagat
     2041 cattccgcga ggagtacttt cttggaccgt aatcgtagaa gtagacttca ctcgcgcctc
     2101 catctcttcg ccgttcacga tctgcaaata acccaatcta gcaatcaacg caacaaataa
     2161 cgtaaatata atgaaaaaaa gaaaatttaa gcgaaaagga acatgggacc ggcgaaacgt
     2221 tttgttctta ggttcttgtg caccttttct tattttttct aaccaagaag tatttaatat
     2281 ttttttcata aaatctttca tcatttccta tccttccgcc tatttacatt catgcttcat
     2341 tgtacccaaa aacttcttaa taaaaaagaa aaaatgggcg gagcaagaaa ttctttacct
     2401 aatttcaaga taaaatcaac tttttgtttc acagcaatca cttaaagtta catatccaac
     2461 tatttttttc attaaaaaat aaacttattt ttgaaaatta tgttttctta agtcgtgaaa
     2521 cactttgatg gatcatttat ttgtggaaaa ctacgttttg ttattctaaa aaacttatat
     2581 aaaaaatagt aaggttttta tttcgaatcc ataaaatatt cttggattgc ttctcgtgtt
     2641 tttttcactt tttcgctaag cttttcgttt ttagccatat agaaataaaa aatgatatcg
     2701 atcgtagcaa attgggccaa aagtgaatta gttgccgcac ttcgattcgt gatttctttt
     2761 ggtctagatg tttgtacgag tacatcggct atcttgctaa gcgggttatt tccaaattgc
     2821 gtcaacgcaa tgatttcgat attcatgctt ttcgccagct cggctaatgc gactacatct
     2881 gcacttctac ctgagtttga aacaagccaa agcactttct ttttctcatt gctgacaagt
     2941 tgcgggagca agacgtggat atctttttca aaaatgattg gcttaccgac acgagaccat
     3001 ttttgcagaa tatcttctac tactaaagaa gaggcgccaa ccccatataa aaaaacagtc
     3061 tctgccgatt ccaaacactc tacgactttt tggatcgttt cttcttctag aatatctact
     3121 gtttctttta tcgctacttg tgcattgtta ccaagtttgt ttttgataga gtaaaaggac
     3181 tcatttgctt ctatatcact aaaaccttca tcgattccag tctgtagttc tgttgaaatc
     3241 gtgattttga agtccgtcag actttgaaaa ccgatttttt tggaaaaacg tacaactgtc
     3301 ggcgcactca acccggaagc ttctgctaat tcattagctg tcattgtagg gaccttctca
     3361 atattaccga taatgtagtt ggccaacttt ttttctgctg aagaataatc ttccatcata
     3421 ctttcaatac gactaattac gctcataagt tcctccaccc ttttaatgat agtctatgta
     3481 agtataccat atcagaccct tattcacggt cgtatactgg ataaaaaaca aaaaaacaat
     3541 ccgcccaaca gaatatctta tcccatcaat cccacagatt ctattgagca tctgtgtctt
     3601 tgaggaatac ctgttatcta ttgttcggat tgctttctat ctactacttt tttacaggaa
     3661 atttacctat tagttttctc tgctgtaatt tttgacttct gcttccatag catcaataaa
     3721 gatattcaaa tcttctacag ctgtttcttt acttccataa cgacgtacgt tcactgttgc
     3781 atcttccaat tccttgtctc caacaactaa ttggtaaggg atcttttgtg tttgagaggc
     3841 acgtatctta tagcccattt tttcattacg atcatcaact tctacacgca accccttcat
     3901 ttgcaaacgt tctttgattt cataagcata atcgccatgt gcatcaacag aaacagggat
     3961 gattgttgct tgtataggtg ccaaccatgt tggaaaagcg cctttgtata cttctgttaa
     4021 ataagcgaca aaacgttcca ttgtagaaac aattccgcgg tggataacta ctggacgatg
     4081 cgtattttcc ccgtcttctc caacatatgt caaatcaaag cgctctggca ataagaagtc
     4141 taattgtata gttgataatg tttcttctgt accaagagct gttttgactt gaacatctag
     4201 ttttggtccg taaaaggctg cctcgccttc tgcttcaaag taatctagtt ctaattcatc
     4261 catagcggct ttcagcattg cttgggcttt ttcccacatt gcgtcatcat caaaatattt
     4321 atctgtattg tttggatcgc gatagctcaa gcggaaacga taatctgtaa tattgaagtc
     4381 agcatatact gccaccatca attcaagcgt acgtttaaat tcatctttga tttgatcagg
     4441 acgaacaaat gtatgaccat cattcaacgt catttctcgt acacgttgta aacctgacaa
     4501 agcacctgat ttttcatagc gatgcatcat tcctaattca gcgatacgaa ttggtaattc
     4561 acgataagaa tggatcgtgt ttttgtagac catcatgtga tgagggcagt tcattgggcg
     4621 aagaacaagc atttcgccat ctcccatatc cattggcggg aacatgtctt cttgataatg
     4681 atcccagtgt ccagatgttt tgtacaactc aacatctccc attattggtg tatatacatg
     4741 ttggtaacct agactaactt ctttgtctac gatataacgt tcgatcgtgc gtcggattgt
     4801 tgcccctttt ggaagccaga atggcaaacc agaacctact tctggggaaa ccatgaacaa
     4861 gtcaagttct tttcctagtt tacgatggtc tctttctttt gcttcttcac ggagacggat
     4921 atattctttc aaagctttct tgtcaaaaaa ggctgtcccg tatacacgtt gcatcatttg
     4981 attgtttgag tttccacgcc aataagcacc tgccactgat aataatttaa atacttgtat
     5041 acggccagtg gatggaacat gtggtccacg acacaaatcg atgaattcgc cttgttgata
     5101 agcagtaatc acttcttctt ctggcaattc actaatcagt tctactttgt acggatcact
     5161 tgcaaaaatt tctaatgctt cctgttttga aagaacacgg cgttcgatcg gcagattttc
     5221 tttgacgatt ttcatcattt ctgcttcgat tgccggcaaa tcttctgcag ttacttggtt
     5281 ttgtccatta tctgtatcgt agtaaaaccc tgaatcgata gctggtccaa cgccaaagtg
     5341 gatatttgga tagaggcgac gcatggcttg ggccatcaaa tgagctgctg aatgacggac
     5401 taagccaagt gcatcttcat ggtctggtgt gatgatctca atacttgcat cttcctcgat
     5461 tggacgagtc aaatcaacga gttttccgtt cactttacca gctaaagctt tttttgctaa
     5521 gctttttgaa atgctttcag caattgccaa tgttgttgtt ccagactcaa attctttgac
     5581 tgcaccatct ggaaaagtaa tttttatcat aatagtttcc tccttgaaat gttttgattg
     5641 atcagatcat caagctgaaa aacaaaaaaa tcctagcatc tcttgaaaag agatactagg
     5701 acgaaaagtt cgtggttcca cctaatgttc aaacgcaaat gcgttcctca agcgttgtaa
     5761 cggtccgacc gcccttgctt caacaagggt ttcgaaagtg gtcatccttt ggttttctcc
     5821 tggaaaagtt tcagcctagc ttttcctctc ttatcgaaga ctctcaaatt cagttggctt
     5881 tctcatcaat caattatgtg tttatttaac cactaataaa tagaaaaatc aagtgggaaa
     5941 ctaaacttat tttttccatt ccccatttac accgtatgtt ccttttttca tctcattgat
     6001 gatgacatgg atgtgttctt ttggtgcctg cgtgttttta tgaacagctt ccgtgatatc
     6061 tttcatcata ttttctaatt gttccggact gcgaccttct actaattcga catgtacgaa
     6121 tggcataatg ctctctcctc tttctgatcg ttcttttttc aactcgattc tatcatacta
     6181 tgtttgtctt gggtactgaa tcaggaaaaa tggctggatc tttttttgct ctcaaggcac
     6241 tcaaaataga gaccgtatcc acgacttctt gcaaaacagc tccgaataat gcggggatta
     6301 gtcccgtact tgcaattaac atcaaaaaaa tacaaataaa gatgccaatc agtacagact
     6361 gtttcgctat tctcatcgta tctcttgaaa tcactactgc ttttgctaca cgcaagagat
     6421 catctttcaa gatgaccgca tctgcacttt cactagcagc tgtagaacca tgagccccca
     6481 ttgcaatacc gatatctgca gcagcaagtg ctggtgcgtc attcacgccg tctcctacca
     6541 tcgcaacagg tctttgatct ttagggatac tttctaaaat ggtcagttta tcttgaggca
     6601 agctacgggc atgtacagaa tctaattgga ctttttctgc aatcgtttga gcaatggcag
     6661 atccatcccc ggtgatcatc atcaaatttt tcacatcaag ttttcttagc tccttgattg
     6721 tctttgctgc ttctgggcga atctgatccg aaaataggat cgttcctgca aaagatcgat
     6781 caattgttac atagattgct gtattggacg tttctatttc ttcagctgaa acaaaagagg
     6841 cacgtccaat ctttacttca tgattattga ctactgcttg gattccttga ccggtcactt
     6901 ctttcagttg actaacagga tacagttggc tgtttttcac gttgttcact aacgaacgag
     6961 ctaagatatg gctagattcc tgttctgcac tagctgcata cagaagtagc tcttcttttt
     7021 ttattccatt gactggctga atcgcctcta cttccaatat ccctttggta agcgttcctg
     7081 ttttatcaaa agcaatcgtt tttgtacgtg cgagcttttc aatcgttgtt ccagttttta
     7141 caacgatccc gtttttactt gaacggctca ttcctgcaac taaagcaatg ggcgcagcta
     7201 gaatcagtgg acaaggtgat gccactacca gtacctcagc aaatcgtaaa gggtcttttg
     7261 agaaccacca agaaatacca ccgatcaaat aagcaatcaa cgtgaaaggg actgcataac
     7321 gatcagctaa acggacaaat cgggcaggct tttcttttga ttcttcgact agtttaataa
     7381 tcatttgata ctggctgtct gcggcacgtt tttcagcgat catttggatc gatccgtctc
     7441 catttaaaga ccctgacata atctgatctc caggtttctt ggtttccggg cgggactcac
     7501 ctgtcaaaga agattcatcg accgaagatt ctcctttggt cactcgacca tctgcgggta
     7561 caagttcgcc aggcttgact agtaactggt catcaatatt tatttcatcg attactatat
     7621 cctgcaattt tccttctttg aatcgatggg caattcttgg ggtgttatct aacaaagact
     7681 gcagttcttt acccgctcgt ttattcgcgt aatcctctag actatctccg cccgtaagca
     7741 tgatcaatat catcaaacta gcccagtatt ctttgacggc taatgttgca aggattgcgg
     7801 taatcgctaa tacatctacg ccatatcttc ctgaacgtaa cgtcttgatc atttccaaaa
     7861 acatcaagaa ggcgagaatc cctccagtaa atgcgacaat cgcaaatgca agggccggct
     7921 ggtgaaaaac aaattcactt aataaagcta tcccaccaat aagcaaagta agtaaaaatt
     7981 ttttgaaatg tgtcattgtt ttttctcctc ttttatgtga cttagagagg ttagtaataa
     8041 atttccagct gcctctttca tcttaagcat agtccttgac tagcactttt taaaacaata
     8101 ggccttaatt gaaaacaact atcactatca gcgtttccaa aattcatcag ttctacaaac
     8161 aaaaatattc agcaaggatt actttttcga ttcatcagtt aaaaagtacc ttttttcgaa
     8221 aaactatgct atacttttaa ttcgttattt acggcggaag gagcaaacat gcgatgaatg
     8281 agaaacaact agaacaaacg cacgtggatg aaacgatcga actaatccag atcgaacaaa
     8341 atatgctgga tacaaaacaa caagaattga ctcaggaaat gaatcattcg acaaaagaca
     8401 cagctaatca caagattcga gctggttcca atgaagcttt ttatgaatct gctgttgaat
     8461 atcgccaaca tgagcaggaa ttgcttttga aataccatac tcttgaagca cagcaaaaac
     8521 gcctgcaaac gttgtctgtc atgaaagata gtccttattt tgcccgtatc gactttaaag
     8581 aagaccgtga aacagaaaca ttatatctag gtatcgcttc tttaagagat ctggcagaag
     8641 aaacaatcgt tattgactgg cgcgcaccaa ttgccaatct ttattatgaa ggtgagattg
     8701 gtcccgcatt ttatgaaact gaaacagata gaatagatgt cgatctgcag ttgaaacgac
     8761 aatttaaaat ccaagaagga cgtattttat ctatggtaga tacgtcggaa gtaatcaatg
     8821 atgacttttt gctagagata ttggatgaat catcaagcaa ccatatgaaa aacatcgtct
     8881 ctacgataca aaaagcacaa aatgcaatca ttcgggacac aacaagtaaa gtaatgctga
     8941 ttgaaggaat cgccggaagt ggaaagacat ccgctttgct tcaacgtatt gcttttctgt
     9001 tgtatcataa tcgcaagtgg ctcgaggctg aaaacgttct tctattttca cccaaccatt
     9061 tgttttctga ttacatctcg actgtattgc cttcattagg tgaaagcggc gtgcctacac
     9121 agacattcaa aaattatttg gtgcagctgc tgccagagtt ttctttacta gatgaacagc
     9181 aacaagaaag tggttttttg ctaggggaaa aagatccgat acaagtgatg aaaagcggat
     9241 tgaccttagt cgatcagatt gatcgctata tccaaggcat cacaaactac ggtcccttgt
     9301 tccgtgatat gaaaataaat ggccgtacga tcctatcaaa ggaatcgatt cgccaatggt
     9361 ataaagaaac aaatgaacaa ttacctttac atcatagact ttctctatta caaacgaagc
     9421 tcctgaaaaa attaggcggt ctgcaaaaag acgaaacacg tcagcaatgg gtcaaagatc
     9481 tggcggaaga acagctccaa gaactatacg caacagatcc aaatcttgaa tatacagaac
     9541 aaaaggagcg ttcattacgt aaaaaactgg ccaaccaaat cgtacgtaaa agattccgtc
     9601 gaatccatcg agggatcatg aattatcaat ttgtcaatat aacgaaacaa tatctccact
     9661 ttctacaaac tgtgccactt tctcttctaa cacgacataa aatcagcgag accaggtggc
     9721 aggaacattt gacaactgtt cgtacacact tgcgtcaaag agaattgcgt caagaggatg
     9781 ctgtactatt ctttttactg atgcgccgaa catatccagt gacggttaca cacaaagctc
     9841 gctatatctt tattgatgaa atgcaggatt tcgcaccatc acaagtggca ttgctgcaag
     9901 ccttgttccc aaaagcaaat ttgactttct gtggagatct aaatcaaaat gtctttggaa
     9961 atgaaacgat cgttggatca ttggaagacc ttttcgtgga ccgtgaagtc actcgtttcc
    10021 aattaacgac aagctatcgc tccacaaaag aaatcactga ttttgctaat cattttattg
    10081 tgaaagaaca tcaagtagaa acaacagcaa gaaaaggaga ccttcctttg ctcatccaag
    10141 gaacaacaga tgatatcaaa ttgaattggt tagcagatac cattcgaacg actcagggaa
    10201 aagcccggta ttggcgtaca gcaatcatag ctaaaacaca agaagaatgc gaagctcttt
    10261 atgctcaact gccagacgag ttgaaacaac aagtccagct gattttaaat gagagtgact
    10321 ttatgaagcg ttccattatt ttacttccag cctttttagc aaaaggtctg gagtttgacc
    10381 gagttttctt gtgggatgta gatgcagaac atttttcttc tcagcaagac aaattgatcc
    10441 tttacaccat gtgtacacgt gcgatgcatg aattgaccct ttttacctcc aataatgaaa
    10501 gtcctttgtt aaacaatatg gatatttcat cttatgagaa aaaagtactg taagtaaaaa
    10561 gacaactgct atcattaatg ttagcagttg tctttttatt tacaataata attgcagaaa
    10621 aagtaattca atcatttaag gtcatttatt ctatatataa atccaaatct gtttcaggat
    10681 attttaattt gacaagcgaa ataatcattt tcagttcttc catgttttct ggatattctg
    10741 ggtcaaatac cttgctatga cggccaatcc cgccattgtc gatcaatcgg taaattcgat
    10801 tccattcaat gaattggtca attgattgga aattgctgat tggatagccg ccacaatcca
    10861 aaatctctga tacacgaaat gctaggtatg cactatcgat cactttattt tttttcgtgt
    10921 ctatcttctc atttctttcg ataagaattt tttcaggacg atgtttcaag ctccactcta
    10981 atagtagaaa gaaagcctcc atccgatact cttcttcaaa taaccgaaag gctgaatcag
    11041 aacgacgaaa aagcagcgga atcagataat tttgtctata aatcagcatt ggtgcgcggt
    11101 ccaccataca ctctaaataa cggttcagat accctgtacc gacatagttt cctaatcgat
    11161 agccttcaac gccgaatctt gcgtattttt gcgctaattt tgaacaatca gttacgttca
    11221 cagctaactc ttctactttg cggtaaccgc ttaagatacg ttcaaaaggt tctaaagtga
    11281 tttttgcttc catattcttc cccgtccatc ttccacatac ttcatatcat ttcacatgat
    11341 acttatgctc tcatcatacc acaggttgaa ttagaaaaga aaataaatca cacaaaaaag
    11401 caagacaatc tgttagtgag attgtcttgc ttttcgaaaa agactgaata cttttcgtta
    11461 aaactggttg cttagtcttc taatgccaca ttatggaaca catgctgtac atcttctaga
    11521 tcttccagtg catcaatcat tttttcaaat gtttcttgat cttctggaga tagtgttacc
    11581 tcgttttgag ggatcatttg gatctcagcg attgaaaaat cagtgattcc tttttctttt
    11641 aatgcttctt gtatactatg gaaatccgct acttcaccgt aaacgatgat ttgtccttct
    11701 tcttccatta catcgcgaac atcgatgtct ttttccatta ggtattcaag gatctcgtca
    11761 gcgtcttctc ctgcaaaagc aaagattgct gtattgtcaa acatgtaaga aaccgctccg
    11821 gaaacaccca tgttcccgcc atttttccca aatgctgccc gtacgtctgc tgctgttcga
    11881 ttcacattgt tcgtcaatgt atcaacaatc accattgagc cgcttggtcc aaatccttca
    11941 tagcgcaatt cagagtatgt ttcatctcct gcaccttttg ctttttcgat tgctcggtca
    12001 ataatatgtt ttggtacatt ataagtttta gcgcgatcaa tgacgaaacg tagtttttgg
    12061 tttgcatgcg gatcaggatc acctgatttt gctgccgcgt agatttcaat cccaaatttt
    12121 gcataaatcc ggctattatt agcatcttta gcagttttct ttgctacgat atttgcccat
    12181 ttacgtccca tattttcact tcgctttctg atttgatagt ttcataacgc aaaaacgtcc
    12241 tgttccatta tacttgtgaa tcacgattct gtgaagcttt ttttctttct tccttcattc
    12301 ttctcatttt tagtcaatta tctatactcg gattgggatt tgcccgaaat tctgttccgg
    12361 aatattgcct cccaattgat agatttgatc acttctaact aacagttccg cttcttgtgc
    12421 ctcttttttt ccgattcggg aataaataga aatctctttt ttttctttta agaatcttct
    12481 tccagcatcg gtaaatccaa gtagtcgaag ataattttta ttttgttgga caggaatctc
    12541 ttgctttttg atattcagca agacataaca agataatcgt tggatccgtg tccatgtata
    12601 tctttttgtt tttacctttg acacaaaatc ctcaaaacta tcagcagttg cagctgctgt
    12661 tttcatgcgc gattctattc cttcggtcat ctgatagata tctgtcagtt ccagcaaagt
    12721 agaagataac aaccgataac gcaaatacgg ccaataagat tcccaagtct gcagcgaaca
    12781 agttgaaaga tcttcttctg tctgaggcgg cacaagtcca gctattcttt ttccttcttc
    12841 taacgcatgg cgaatggctg ttgcactggc tatcctctga tctgtgatga ttttttcatg
    12901 atagcctgca cttttacgtc ggatcggatg taattccata gggtggacat acttggcatt
    12961 ttcctttgca taacttaatc ccaagatatg atttggcgaa gaaaaatcaa gcgtaatatc
    13021 gggatacaga ctgcgaaaaa cctcagtcat tttttgcgga taactatacg tttgatcaga
    13081 cagttcttga aatgcctctt ctatcctatc ttgattctct tggacaaagc gtccgaaact
    13141 gctgtaatca aacgaagtct cttcttctgt tccaaaacac aaactgtcac agtccagtgt
    13201 ttgcaagatt tttactgcac ctttagcaaa atagtcagct gactgaaccg cccattcgac
    13261 gggaagctcc actactaaat ccacaccatt ttgtaaagct tcattcgcgc gatgccattt
    13321 atcgatgata gccggttcgc ctctttgcaa aaaattcccg ctcattacag caatgacgac
    13381 ctctgctcct gttatttttc gtgccatttc cacatgatag cgatgtccat tgtgaaaagg
    13441 attgtactct acgataatcc cgcagctttt catgcgcatc ctccttcata gttatcgata
    13501 aaaaagaaat agagacaagt aaaaaaaggc aaaaatcgga aaaaataccc gaactatata
    13561 aactattctc gcaaacacaa tacttctgcg acgaaaagct gcactgcaag agcaatgcct
    13621 atatcgttcg gatatataat ttatgttgaa gatttattct tttcttgtta actcgagcag
    13681 gcaaaaccgc tagtctttgt atgctacaaa gaaccagcgc tttgatttct ctgatgctgc
    13741 ttcgtctgta aaatcagaaa atgcttcgac tttcgaaaag ccgctgtttt ccagcattct
    13801 taaataactt tccaatggat aggtacgctc ttgatgtagt tcatcttcac gaataaatcg
    13861 accagaccct tcttgttctt caacgaaaaa ggtaagaaaa tgttcgatgc tgtgtttctc
    13921 gcttcctgga taactatccc acaaaaaagc aaaattatcc ccttgataat gatagctata
    13981 ttctggaaaa acctcatcta cttgataggt ggagtgtacg tcaaataaaa atcggccatt
    14041 ttcttctaac gcttgataga cttcatcaaa cacttgctgt acctcttgtc tatttttcat
    14101 atagcacagc gaatcagaaa aacaggtaat tgcctgatat tgtccgattt ctgataaatc
    14161 gagcatattg ccttccacaa attggatcga tgcgtcttct tcatatgctc gctggctggc
    14221 aatcatcaac atctcttctg aaaggtctaa ccctgtcact ttatatccat cttttgcaaa
    14281 ggcaaccgct aatgctccag taccgcatgc cagttccaaa atattttttg tgtcttcttg
    14341 taaatgacgt ttcgaaaaag ctaaccattg ctgataaagt gtttcgtcca tcacttcatc
    14401 gtaaatgaaa gcaaatgttt cataagccat atgttaatcc aaccattcac taagatcgac
    14461 tagcggagca tctgaccata gtttttccag attatagaaa tttcgttctg gcgcatggaa
    14521 aacatgtacg atcacatctc caagatcgat caatacccat tttccgcctt cttttccttc
    14581 aatacgtttt acttcatatt tgttttcttc ttctttatca atgatttctt ctgtaattgc
    14641 gttgatttga cgttcgctat ttgctgaaca gatcatgaaa taatctgcca acaaggaaac
    14701 atttcgaacg tctaaagcga taatgtcttc tgcccgtttt gaatctgctg cttcaatcgc
    14761 aatttttaat tgttctttac tatctatgat gatttcctcc taatatgagc agcttatttt
    14821 tttgctaccc agtaattata tgtttcgatt gtttttggat aaatctgttg ttcttgcgca
    14881 agcaaatggg ccaatgtatg ttttgtttca aatgctacag cttcgtctag atcagcccat
    14941 gcaatggctc gtgcatcttg taccccagga aaatctcgac ctggttcaat atagtctgct
    15001 acataaatga ttttgtcaag gagactcatc ttagcagccc cagtcgtatg cacccggatt
    15061 gcatgaagaa tctctgcatc ggtgattcct aattcccgct ctacaaacga agcgccaaca
    15121 agaccatgcc agattgcatt attataattc aataactccg gatcaaaacc gtctcttacg
    15181 attaccattt tgaactcctc atctggtcgt tcttttgcat aatcatgtgt caatgcagca
    15241 atactagctt tttcaggaga agcaccgtat tttttggcaa gagccacggc tgtttcttct
    15301 actccaagca catgcttgaa gcgttgttcg ctcattctca tctgtatttt ttgcatcagg
    15361 ttttctctag aataagcagt atattcatta ctatagtcca tattcataca acccttcatt
    15421 ttgaatataa tcaattactt tatctggaac aaggtagcgg atagaacagc cttctttgat
    15481 cttttgacgt attttcgtgg aactgatgtc gatctcaggt acatctaccc aaattacagg
    15541 atatggagta tccgttgtgt atcctggtcg acgtataccc acaaagttga ccatagaagt
    15601 cagctcatcg attttatacc attttggcaa atattctacc atatccccac cgataataaa
    15661 gtaataatct gtatccggat tgttttgcgt caattccttc atagtatcat aggtgtaact
    15721 tttcccacca cgagctaatt caatcgtttc aatctgcaaa aaaggattgt cttccaccgc
    15781 taattccaac atgttgagtc gatgttttgc atcaatcgtc tgtttctcat caacatgagg
    15841 tggctgataa gaaggcatca aaaatacgcg gtcaagacct aaattccggc cagcttgttc
    15901 agccatcact aaatgtgcaa ggtgaacggg attgaatgtt ccgcccaaga tccctacttg
    15961 ctttttcttc tctaagaatt gaggcatttc ttcaggaaat aattgtgaac gaacaaatgt
    16021 cttagcttgc gtattcatca tggtcactcc ttatattgct tttacttctt ttgatagcct
    16081 ttgatacttt tcttttgtgg aaggtttgta taatacaata acacgtccaa tgatttggac
    16141 gatttcgcaa tctatttctt tttctaatac ttgagctgct tcttctgcaa tctcatctgt
    16201 attttgaagt aacgatactt tgatcagttc tcttttttct aaagcttctt caatttgaac
    16261 gatcattgct gaattgatcc caccttttcc gatttgaaaa atcggctgaa gatgatgcgc
    16321 tttgctacgt aaaaaacgct tttgttttcc tcttaaactc ataattttcc ttcttcctta
    16381 aatcaatgct ttgcgtttca atacatctac accctttggc gcccagcccg caattactac
    16441 tggcgctgtt acagtgatcc agcctagacc ggcaaaaacg atgtctgttt tttctttcac
    16501 agaaaactca aaacgaacaa gctccggaaa tgcctcgact tcatcaggac gaggaggctg
    16561 taataatcca cctacatgtt tttgataaaa ttcgtctgct ttttccagtt tcgttcgatg
    16621 aatatttaca tcatttgaca cataagcaat aaatgaagca cgattgccgc tgataaaatc
    16681 aaatcttgca agtccgccca agaaaagtgt ttgcccttca ttcagctgat aaactttagg
    16741 tttgatttct tttaacggtg caatgatccg caaatctttt ttacctaagt agtgcgccat
    16801 ttgatggcga tggataattc ccggtgtatc aatcaaaaaa tgcccgtcat ctaaaggaat
    16861 ctcgatttta tccaaggtcg ttcctggaaa ctgcgaagtt gtgattacat cttgtactcc
    16921 cgctgtattt ttgatgattt gattgataag cgtcgatttt ccgacatttg ttactccgac
    16981 gatatagaca tcccgtccat cgcggtattc ttcgattttt tctaatagtt ccgtcatctc
    17041 atgagatttc ttagcactag ttaataatac atctactgga cgaattcctg cttcgtaagc
    17101 acgttccttc atccattgtg ttaatttagt ttttttcaat gatttaggta atatatccac
    17161 tttgttccca actaaaagta ctggattgtc accgacaaaa cggtgtagtc ctgggattag
    17221 tgaaccattg aagtcaaaaa tatccaccac attgacgatc aatgcatctt tttgccctaa
    17281 ttcattcagt aagcgcaaaa agtcgtcatc cgtcaatgag acatcttggg tctcattata
    17341 atggcgtaat ctgaaacaac gctgacaata gacttccccg gaagctaaac ctttttccaa
    17401 agccgtttgc ggcgtgtatc ctaattcacc gggtttgttt gtttgtataa cggcaccaca
    17461 gccgatacat tgtaattctt ctgtcattcg attccacctc gccagcccat atcagggtgt
    17521 tttgctaata gataggccat aattcttttt tcccaaaaac gattaaattg tgtcttccaa
    17581 ctatctgttg cgataatggg ttttacaagg atgctacgta tccctgcacg attggctcca
    17641 cgtatatcag tcataatctg atcgcctacc attactatct catcatctgc taaatccaat
    17701 tgtttctttg ctatgttgat ccctcttgct aaaggtttca ttgctcgtgc aacatacaaa
    17761 agatcaaatt tttcaatcgc tcgcgcgaca cgttttgaat tattgtttga aacaacaaca
    17821 acagggattc ctgcattttt catttctaaa atccaagtaa gcaactcttc tgttccatct
    17881 ggattattcc atgcaatcaa cgtattgtct aaatcggtca atactgcttt gatgcctaga
    17941 ttctttaatt gggcaggtgt aatctgatag atggcttcta ccatccatgt tggtttgtaa
    18001 tttgaaaaca tgctgtctcc tcatctgcaa aaaatgaagg agcacataaa gtactcctca
    18061 accccgtatt atactgcata tcagcaaaaa aaactacctc tatactcgtt cgtctttcag
    18121 aaaaagcatt tctttacaaa atgaccaaaa ataaagattg atcacagaaa aatttagaaa
    18181 caaaaaacaa ctaatattgg cggaacctct tgtatcgttt ttccagtaat ttatgctgat
    18241 ctaatcgaac aagttccgtc aatctttcaa tcaacgcttt tttcataatg tgtgcgactt
    18301 tatatcgtgg caactgctcg ccgttgaacg tttcaggaat aactcgatca acgattccta
    18361 actcgcgtag ttctggcgca gtaattttca tcaactcagc tgcttctgcg gcgcgactac
    18421 cgtctttcca caaaatcgac gcaaatcctt ctggagaaag cacagcataa atcgtttctt
    18481 ccagcatcca gacttcatcc gctaaaccta gagcaagggc accgccactt ccaccttcac
    18541 caatgatgat ggcgatgatc ggtaccttta aatcagacat ttcgagcaga tttctggcaa
    18601 tagcctctcc ttcgccgcgc tcttctgctc ctacaccgca atatgcacct gctgtattga
    18661 tcaaggtaat caccggtcta ttgaactttt ccgcttgttt catcagtcgt aaagcttttc
    18721 gatagccttc aggatgggga gaaccaaaat ttctgcggat attttcctgc agatcccgtc
    18781 ctttttgaat accgatcact gttaccggtt tgccatctaa tcgagcgatt ccaccaacaa
    18841 tcgcttcgtc atctgcaaat aaacgatcac catggcattc ctcgaaagaa tcgaagatct
    18901 cttcaaaaaa atccaagctt gtccatcgtt ctttagctct tgctaactga acgacatcat
    18961 gtgctgtctt atccacgatc tatccatcct ttctgtgtat gcaattcaag aagcgtatgg
    19021 attttctgtt tcaattccat gcggggaaca atctgatcga caaaaccatg agataataag
    19081 aattcagcct tttggaaatc ttctggaagt tcctgcttga tcgtctgttc gatgacgcgt
    19141 cttccagcaa aaccgatcaa gctttggggt tctgctagaa taatatcgcc ttccattgca
    19201 aaactggcag ttactcctcc ggtcgtcggg tccgttaaaa cagttagata aaaaagacct
    19261 tcattgctat gccgtttgac agcagcagag atttttgcca tctgcattag agaaaagatt
    19321 ccttcttgca tccgtgcgcc acctgaagct gtgaacaaga cgactggaag actttccttt
    19381 gttgctcgtt cgaataatct ggtgatcttt tctccgacaa tcgttcccat acttcccatg
    19441 ataaaattag gatccatcac tccaataatg aagggaatcc cctgaatggt tgctttacca
    19501 gtgaggactg cttcatgaag tcctgtttta tcttgcattt ttttaatttt ttccgtatat
    19561 tcgggaaatg ctagcggatc tttggttaca agatccgtat cccattcttc aaaacttttt
    19621 tcatcaataa tcaaagctag acgctgccat gcaccgattc gaaaagcgta tccgcaatga
    19681 gggcatactt tttcttcacc gatgtctttc gtataaagga tatgtttgca atttggacac
    19741 tttgcccaca tgttatcagg aacagatggc gagttagcag gtttgctctc tctattagga
    19801 ttgatccgaa tatatttctt tttcttaaac agagccatct atgcgcctcc tatctccgtt
    19861 tctggtgtcc aattcggtaa aaattcttct tgtaaaaatg ctgtgctgta atcacctgct
    19921 atgactgcag gatgactaat caaatccatc tgaaattctg cgttcgtgat gattccttct
    19981 gtgataaatt cacttaaggc tcgctgcatc ttcattaatg cttcaaaacg cgtatttcca
    20041 tggacgatta tttttgcaat cattgaatca taatatggcg ggatcgtata tcccgggtaa
    20101 actgcactgt ctactcgcag tcccatccca cctgctggaa gcagtaagtt ttggatcttc
    20161 cctggagaag gagcaaaatg gaaagcagga ttttctgcat taatccggca ttcgattgcg
    20221 tgtccttgga atactacttc ttcttgacac acattcaaag gctcaccggc tgctatctcc
    20281 acctgttttt ttactaaatc gattcctgtg accatttctg ttactggatg ttccacttgg
    20341 attcgagtat tcatttccat gaaataaaaa tcgccttctt catccatcag aaactcgatc
    20401 gttccggcat tttcataatt gactgcttta gctgctcgaa cagcagcgtc tcctagtgct
    20461 tctctttttg tttgtgagat cactacagaa ggagattctt ccagtacttt ttgattgttg
    20521 cgttgtaaag aacaatctcg ctcgcctaaa tgaatgacat gaccaaatcg atcacctaag
    20581 atctgaactt ctatatggcg agcaggataa atgatttttt ccaaatacat atcatcattt
    20641 ccaaatgccg ctgctgcttc ttgctgagct gaagaaaaat gctgtgggag ctcttctttt
    20701 gattgaactt tccgaatgcc tttcccgcca ccacctgcag ctgctttcag catcactgga
    20761 taaccaattc tgtctgctat ttccaatgct tcttctactg tagataatac accagtactt
    20821 cctggaatga ctgggacatt tgcttcttgc atcaattgac gcgcattgat cttatttccc
    20881 attgcatcga tcgttgcact tttaggacca ataaatgtga tattgcactc ttcacacatg
    20941 gaggcaaatc ggctattttc agataaaaaa ccaaatcctg gatgaattgc ttcggctttt
    21001 gtcacgattg cagcgctcag tacttcctga acattcagat atgaatcaac ggcttttgcc
    21061 gggccaatgc agattgcttc atctgctaac tgtgtatgaa gtgcttcggc atctgcttct
    21121 gaatatatcg ctacggtttg gatccctagt tcgcggcatg cacgaatgat acgtacagcg
    21181 atttcaccgc ggttagctat caatacttta gaaaacatat ttcacctatc caatcataaa
    21241 ggttaattcc gcttcggcta cttttttacc gtctacttta gcgattcctt tgcctattcc
    21301 ggctgaagct ttcactttca atatctcaac ttcaaggtat aaggtatctc ccggtgtaac
    21361 tttcttacgg aattttgctt tgtccaatcc gccgaaataa gccgtctttc ccttgaattg
    21421 ttcaagagaa agtaatgcaa ctgctcctgc ttgagccatt gcttcaacaa tcaatacccc
    21481 tggcataaca ggttcttctg gaaaatgtcc ttgaaaaaag ggctcattga tcgttacatt
    21541 tttcttagca acgatccgtt ctccttcaac catttcttcc actcgatcaa tcaaaagcat
    21601 tggataacga tgtggaatga tttcttttat ttcttgtatg ttcattgttt tccctctttc
    21661 ctgctttgct tatttttgct gaatcctaaa gagtggctgt ccatattcga caactgactc
    21721 gttttctaca aggatttctg tgatcactcc gtcggcctca ctagttatct cattcatcag
    21781 tttcatcgct tcaataatgc agataacttc tcctttggca acttgatcac ctactttttt
    21841 gaaagctggt ttgtcgggcg ctggttgcag ataaacgatt cccacgattg gcgaaacaac
    21901 ctcgattcca tcaaatactg ccgattcttt ttctttcatt atttctggag cagttgttgc
    21961 ttgttcaggt atgacattga ctggctccga aactggcaac gtttcgtttg tttgaaccat
    22021 attcatgcct cgacttgttt tatttttatt catatacaat tcaaattgac cttcacgcaa
    22081 atcgaattcc gttagcgagg attgatcaaa ttgactgact aattctctga tttcattgat
    22141 atccaaaatt attcctccca gcgtttcatg cacagaaccg cattatgtcc gccaaaccct
    22201 aatgaattac tcattgcata agtaaaactt gcaggtttgc tttcgttttt gacaactgtc
    22261 aagtcaatct caggatcttg tttttctaca ttgatcgtag gtgggataaa ttgatgttct
    22321 aatgccagca aagttgccaa ggcttcgatc ccgccggctg ctcccaataa atgtccagtc
    22381 atcgatttcg tgctgctgac gtaagtatct ctgaaatttt cacctaatgc gatttggatt
    22441 gcttttgctt ctgcctggtc attggctggt gtacttgttc cgtgagcatt gatatatccg
    22501 acttgttccg gctgtacacc agcttcttcc atcgcaagct tcattgcttt agatgcacca
    22561 gaaccatctg gagtaggagc tgtcatatgg taagcgtcac agtttgcacc gtatccaacg
    22621 atttctccat agattttggc accgcgagct tgtgcatgtt ctaaagattc aagaactaga
    22681 acgcctgctc cttcacccat cacaaaacca ttccgatttt cgtcaaacgg aatcgaacca
    22741 cgattaggat cagttgattc tgagagtgct gttaaagctg caaatccagc aatccccatc
    22801 tcacaaatcg ttgcttctgt tcctccagca agaatgacat cagaatagcc atgtttgatg
    22861 ttacggaatg cttccccaat tgaattcgtt ccgctagcac aagctgttac gatagctgta
    22921 caaatacctt ttgcacctac acgcaaagca atatttccag ctgccatgtt ggcaatcgcc
    22981 attggtacga acattggaga aactcgtttt gcaccttttt catgtagacg aataacttgg
    23041 ttttcgattg ttggaagacc accgatccca gatccgatga tgacgccaaa ccggtcttga
    23101 ttcatttttt ctttatctaa accgctcatc tccattgctt ctaaagcagc gtagattcca
    23161 tagatcgaaa acatatccat tcgtttgcta tcttttttaa taaaatattt atcgtaaggg
    23221 aaatctttga cttcacccgc taaggtaatc cctgtttctg aagcatcaaa tttagtgatc
    23281 ggtgcgatgc cattcgtccc ctcttttaag ctattcaaaa agctgtctgc gtcatttcca
    23341 ataggtgaag tgactccata gccagtaatt accactcgat tcatttgttt gctctccttt
    23401 tcttatccgt gcatgaccaa tccgccatcg acattgatga cttgtccggt gatatatgga
    23461 ttttgtgcta agaaaactgc tgtttgtgca atatcttcta cttgtccgaa acgctgcatc
    23521 ggaatttgct tttccgcttg ttccttgact ttgtctgcta aaacttccgt catatcagtt
    23581 gtgatgaatc ctggcgcaat ggcattacat gtaatgcctc tagttgcagc ttctcgtgcc
    23641 acagattttg ttaatcctac tacgccagct ttactagctg cataatttgc ttgaccaata
    23701 tttccaatca acccagatac actagagaga ttaatgatgg ccccttctcg ctgcttcatc
    23761 atttttttca atacgtgctg cgtcatattg aaggttccaa tcaaattgat atccagacat
    23821 tttttgaaat cttctgcatc cattcgcatc acaagtttgt catttgtgat tccggcattg
    23881 tttactaaca catggatcga tccaagcttt tcttctgctt ctttgatcat ttgtcccgct
    23941 ttctcataat cagagatgtc accggaaact cctacgcatt ttacaccgaa tgcttcgatt
    24001 tcttctatct tttcttttgg aatctctccg cgaccattca aaatgatatt tgctccagct
    24061 tttgcaaaag ctaaggccat cgctttgccg attcctcttg tactacctgt gataaataca
    24121 ttttttcctt ttacatccat aacgttcctc cttatagtat tgctattgtt tcatcaaatg
    24181 tctgcttatt ctcaacacgc agaactggta ttgttttatc gatttttttc ataaatccgc
    24241 ttaatacttt tccggggccg acttcgatga cttgttcgat gccgattgtt tttaacttat
    24301 ggatactctc atagaaacga acaggttgca tgacttgctg ttcaagtagt cccgcgattg
    24361 tttctttctt cattatttcc gttgttgtgt tgcttatgat aggaaaagaa ggttcagaga
    24421 attgaatctg acttaggtcc ttcgccagtt tttttgctgc cggttctaaa atagctgtat
    24481 gaaaaggccc gctgacattt agagggatca ttcttttgaa ccctttttct tttaatagta
    24541 aaacagcttc gtctactgct ttttcttcgc caccaatcac gatctgctga ggtgtattat
    24601 aatttgcagg agatacgatg ccgtacttgc tagcttcatg acagctttcc tcgatcgttt
    24661 caatcggcgc attcatcact gcaaccattt tcccgcttcc agctggggca gcttctgtca
    24721 tataagcgcc tctttttgct actaacgcaa ctgcttcagt gaaggatagc gcattactag
    24781 ctactaatgc cgaatattct cctaaactca gtcctaaagc tgcatctggg atgattccat
    24841 gctccttcaa taagcgataa tacgcgatgc tgactgttag aatagctggc tgtgtatatt
    24901 gcgtctgatc caaacgttca ttttctgtaa agcaaagttc agccatatcg tagccgagaa
    24961 tctcacttgc ttcatcaaat gtctgcttta caacggcttc ttcatataaa tcttttccca
    25021 taccttgata ttgtgcacct tggccactaa ataagaatgc tgttttcatg tttttctcca
    25081 atatatccag aatatatgtt tgattcttcc tattcaaaaa ggccgagaca ttcctatttc
    25141 aggaaatgtc ccagccccca acctaatttt aatgattatg cagtttgttt ttctacgtaa
    25201 gtcactaaat cttgaaccgt tttgattccg tcttctgttt cgattttcac gtcaaattca
    25261 tcttcaattt cattgatgat ttggaataaa tccaagctgt cagcttctaa gtcttcttgg
    25321 atgtcagtag tcaatttgat ttcttcagtt tcttttccta attcttctgc gatgatttct
    25381 tgaatttttt cgaataccat aataatatat tcctccgata ttgtttgctt tttattttta
    25441 taatttaaca gtctacaact ccatgagaat acttccccat gttaaacctc cgccatagcc
    25501 tgtaaatatt actttctgct gttttcctaa ggtgatcttt ccactagaaa ctgcttcatc
    25561 caataagata gggatgcttg cagcagatgt attcccatat ttatccatat tggtcaggaa
    25621 cttttcttgc ggcatcttta cttttcgggc aattttctca ataattctga ggtttgcctg
    25681 atgcaaaagc agataatcaa ctggtttgtc tttcatgact tcttggatat tgtttgcaac
    25741 gtctcgtacg gcaaaatcaa aaatatctct gccagtcatt tgcaaataat acgaaccttc
    25801 tgaatcttct gaatagaacg gatttttatt ttgctggtag ccagcggtca atgagctact
    25861 tctggtaccg tcagctgcta atttttcttt cagcaatttt ttctgtggat tcgcttctaa
    25921 gagaatccca cctgctccat cgccaaacaa cacagcagtc gtacgatcag accaatcgat
    25981 tagcttagat agtgtttcac caccaatcac cagtccctta gttgagccgc agcggatcat
    26041 tttttcagcc atgcttaacg cataaacaaa tcctgagcac gcagcactga tatcaaaagc
    26101 gatagcatga gttgctccca atttcccttg tacttgtgct gctacagatg gtgtcgtgta
    26161 atcgggcgac attgttgcta ctaaaataaa atccaaatct ttagggttta gatttttctg
    26221 ttttatcaat ttttccgcca ctaaaatgca taaatcagaa gtctcctgat ttgttacaca
    26281 tcttcgttca cgaatacccg tccttgacga aatccattca tcagaggtat ccatcatctt
    26341 ggaaagatca ttattagtaa taatcttttc aggaaggacg ctggctgttg cagtaatcat
    26401 tccaaattgt tccattaaat atcctcactt atagtcttgc aagaagtcgt gcaagttttt
    26461 cagtgcatcc agcaaggcat gctgttcctc cgtagccatt ccgtctaaga tgttcttgac
    26521 catttcacga tgaaaatgct gatggacccg aaatagtaac tttccttttt tcgttagtcc
    26581 caactttaca acgcggcggt catcttcact gcggatacgt tcgacatagc ctttttttac
    26641 taacttgtta atagcagtgg tcaaggtccc aacagtaatt gatagttctt tggctacttc
    26701 tgaagttgtt tttttcttgt acatcccgat tgcctcgatc gtgtgcatct ctgtgattga
    26761 cagatctttg aattgagatt ttttcagctc agactcttcg attgtcaaaa tatcattgaa
    26821 gacactaaca agataatcat ttactgtttt taaatctggt tccatgttcc accgtccact
    26881 aattagtttg attatcaaat cttttgatgt tcaaactata tcttaacttt tttcaaaatg
    26941 caaccttaaa agatcatttt tttactatat gagctttttt taagatttta ctcatttaaa
    27001 acaactgata aatcagcatt tataatttct tttattagaa aaatcatcta tctcacatat
    27061 tttgattatc aaagtatttt ctgtgaacag aactatagaa ttccctaaaa cttgtccatt
    27121 atttcaaaat ttgttatagt ctttttattc aaagcgtaaa aggagatcct atgttaaaag
    27181 aaaaaatgaa aactctcccc atgctgccgg gtgtctatct tatgaaagac cgagatggta
    27241 aggtcatcta tgttggtaaa gcaaaacggc tcaaaaatag agtaagcagc tattttcatc
    27301 agaataaaca gcattcaaaa aaagtattac gtatgattca tcatataaca gattttgatt
    27361 tcgtcgtagt agacacggaa ttagatgctt tattgctcga gtgtcaattg atccaacatt
    27421 accgtccttt ttataaccga caaatgaatt atttcagtaa ttataattat gtacatatta
    27481 ccaataaggg atttgtatta acagatactc ctacggctcg aacatacggg ccttttcgtc
    27541 tctataaaaa aatgccgtct attttgcgta taatggaaga aacttatcaa atgccttggt
    27601 tgtctgaaat tagtttgtta gctttgcgag tccagcttcc tgacctacag gaaatgactt
    27661 ttgaacagaa aaaaaaggaa ctccaagggc tgtttcaagg ccgaaataaa aagctactga
    27721 cttacttgaa aaaaagacaa caacatttca tctatcagtt gaatttcgaa aaagccggta
    27781 tgcttcaaaa agatatcgaa ttagttactt attttattag acggatccag gaacaaaagc
    27841 agtttttaag aacaccatcg ctcaccttca gcatgccatt agcagcagat gagagtcaga
    27901 aaaagcacta cctcgtttgt tatggtcaac ttgcagaaac aatgattacc tctggtgacg
    27961 tttctcctga cttctattat gaaaagaaag aagctcattt atctttgaaa cgtcaattgt
    28021 caaaagaaga aatcgatcct gtacaaatct tgatcagtta ccgcaaaaaa ttagaaaaag
    28081 aacagtttga aattgaactg ttaaacaaaa aagaagctga aaagcaacta aattagttgc
    28141 ttctcggctt cttttaggca tcttcaactt caaatgtcaa ttatcctaaa atttattgga
    28201 ttaagtcata gatttccatc gctacgatat cgatattatc aaattcgtat tgctgatgag
    28261 tatctgtttc agttaattca aatgtatcgg tcgctttatc ataagttact gtacacttct
    28321 ctacgccttc tttttcaaaa cggcgaactt gcagttcatt atctgctgac tcgaccatag
    28381 cctccagtcg ttttatgatt gcgactaatt gtgaatgtgt catcggaggt cctccttttc
    28441 ttatttctgt tatattgtat caaaagcata gcctacttgc attgattttc tctaaaaaaa
    28501 ctcgtttttt atgatttttt ttctggtatt tttccttcag gccaccaaag tttgatcaaa
    28561 gcttgggttc cgtcattctc aaaaccttta tctgccaact cttcatatag tttcaatgct
    28621 tgggtagttg ctggcaatac aagatccatt ttttctgctt cttctaatgc aatctttaaa
    28681 tctttgataa aatgtttgac aaaaaaacca ggtgtgtaat cttcttttaa aatacgagga
    28741 gaataattgc ttaaagacca gttagctgca cttccacctg aaagcgtctc aatcactttc
    28801 tttaaatcaa gtccgttttt ttgtgcatag acaagcattt ccgtcattcc tgtcatcgta
    28861 cctgcaatca tgatctgatt agccattttt gtatgctgac ctttcccagc agaaccatgc
    28921 aatgtaaatg tcgtaccaaa ttctttgaat aaaggcagta cttgatcata aacggcttct
    28981 tctccaccga ccatgatcgt cagtgtacca ttctttgctc ctaagtcacc accggatacc
    29041 ggtgcatcta acgcatctgc gcctttttct tttgctgttt ttgcaatttt ttctgccagg
    29101 cttggtgtac ttgtagtcaa atcaactaaa atatgtcctg agatatctgc agaaaaaatc
    29161 cccgactgtc catagtagat ttcttctaca tctttggggt aacctaccat tgtaaagaga
    29221 atattacttt gttctgctac cgcttttggt gtatctgccc agatagctcc ttctgttact
    29281 aaaggatcag cttttgcttt tgtccgatta tagacagcta cttcgtgtcc tgcttctagt
    29341 agatggcgtg cgacagcact tcccatgacg cctgttccga taaaaccaag tttcattttt
    29401 tcgacctcct aaaaatcaaa aatccttgct tctatgctag tatacgctag aaacaaggat
    29461 tttttcataa aaaatgtttg aattttatct tttaaatgaa tttaatttta ttttgattcg
    29521 ttcaatcgag tcttcttctt cttttcttcg catctcttct tcatgataaa caaccatgtc
    29581 ttgataaaat tcgatcatag cttcgccgaa atgtgtagat gaaatatcat aaagtttagc
    29641 ttctaaaact tttggatctt taggaacttc actggaaata taatcaataa gtgctggtgc
    29701 aaagtcttcg tcggtttcaa aagttttccc taatgaagga tgatcgaaca atcggttcaa
    29761 ataagcattt ccttccacga cacaaggtgt tccggctgcc atcgcttctg tataagtaag
    29821 cccttgtgtt tctgaagtag aagcactgac aaaataatct gccgctttat aataaagtgc
    29881 tacatcattg ttgtccactt ctcctgtgaa ctgcacaaat tcttctaact gcagttctga
    29941 gatcaattcc tctaactctt ctacataagg tccttttcct acgataacta atctggcgtt
    30001 aggataagcg gagatgacct gaggaaaccc attaatcaag gcttggatat ttttctcata
    30061 agaaatcctg cttaaagaaa gaatcatcaa atggttttcc tgaagaccta gtgactccct
    30121 taatttgctg atatcctgct gagtgatatc agaacgtttg aatttttcaa tgtcgatacc
    30181 agtaggaatc acgcgaagcg gtgctattac accatagctg cgtaatgtat caataacacg
    30241 ttcacttgga caaactacac ctgtcgtatg atttgcaaat aatctagaca agtattttac
    30301 atgggattgc ctgatcactt ttcctttacc gatataatga aggtagtctt catacatcgt
    30361 atggtaagta tggatcagag gtattttcaa cttcttagct accatcttcc caagtatccc
    30421 tgctccgaat tctgtatggg tatgaataag atctagttct agttctttgg caaccaaata
    30481 agcataccac atgcctctaa caacaactct tcgatccttg aaagaaataa atggtacact
    30541 tggcattcga atcacatctt tttccaactt atccgcatta ggatcggtcg ttgtaaaaat
    30601 atagacttca tgcccatgtc tttctaattc ttgttttaat gttttgatcg atgtagcaac
    30661 tccgctgact tgcggaaagt aggtatcggt aaaaaagccg attttcatgt ttttcgcctc
    30721 caaactagtc cttgacctga tttacttttt ttaatttgct agagactttt tcattcagta
    30781 cactttcgta tacattttta agttcttcac cgattttatt gatacttcgc tcttttgctg
    30841 tttgataacc ggcttgtgtc gtactcggta gttcttgatt ggtaatctgt tggatcagtc
    30901 ggataaattc ttcgtttgtc ttccccatat agcagttctt gctatcttct aaccagccat
    30961 tatacactgg aatatctcga acaagtacgt tttgtttgct tgctaaagct tctaaaacaa
    31021 cgatcccttc tgtctcttca taagaaggga aaaagaatag atctgcacct gaatacgcac
    31081 cttctatgat ctctccacga atgtaaccag gaaacaggac attttcagga tgatcttctt
    31141 ttacaatttt ccggatgttc cgaggaatcg agtacatggg aacatgacca aaccaaataa
    31201 atgtgtattc gggcatcttc ttagcaattt ctacgaaatc aatgattcct ttacgttcga
    31261 aaaacaaacc gacacaaatg attacttttt gatccggaga cagtttgaaa tattctctga
    31321 acttttgttc tttcattgga tcagggtgat atttctctaa gtcgatccca ttggaaatag
    31381 cttgaatcgg cacacggata ccatagcttt ccaacaactg ttttgaataa ggtgttggcg
    31441 tgatcagata gtccgctttt tggtacaatc ctaccagata tttttttacg ataggagaaa
    31501 gctggttcga tctgataaag gaatttcgga aatcttcctc tgtagaatgc gcatgataga
    31561 caactttttt tccttctctt ctggctttat tgaccatatt atgactattg attccgtatg
    31621 tattgatgtg caggatgtca taatcttctt tttcatctag tgtataagag ataccgactt
    31681 ccgtcagagc acgtttttga tgatcaagcg cacgcccgat tccagatttt gcaagcatct
    31741 tttcactttc aaaatataat aataccttca ccttacgtcc cccttcactt atatagtata
    31801 acatagccta caaactgtca ctcaaactta agccctattt ttgtctattc ttactgacaa
    31861 aaacgttttc ttaaaaaaga acaaaaaaac tggcgtagct cttttacaag ccacaccagc
    31921 ttttgatacg ttgtttattt tacatattca tgaacaagtt caacgacttc ttccatcata
    31981 tcgcattctt tcaatgcacg atcagcaagt tcagccattt tcgctgtgtc caagcgtttc
    32041 attaaactac gcgttttaag aatagatgtc gcactcattg agaactcatc tagacccata
    32101 cctactagca atggaacagc tgtttgatct ccagccattt ctccacacat acctgcccat
    32161 tttccttcag cgtgtgctgc atcaattaca tttttgatca aacgtaaaat tgatgggtta
    32221 tatggttggt acaagtaaga aacgcgttcg ttcatacggt ctgctgccat tgtgtattga
    32281 atcaaatcgt tcgtacctac agagaagaaa tctacttctt ttgcaaactt gtctgctaag
    32341 actgctgctg ctggaatctc gatcatgatg ccgacttgga tcgtatcaga tacttccttg
    32401 ccttcactta tcaatttttg tttttcttct tcaaagatcg cttttgctgc gcggaattct
    32461 ttgagtgtag ctaccatagg gaacatgata cgtaaattac catgaacaga tgcacgaagc
    32521 aatgcacgca tttgtgtacg gaacatttcg tcgccttgtt cagataaact gatacgcaat
    32581 gcacgatatc ctaagaatgg attcatttca tgaggtaatt gcagatatgg tagttcttta
    32641 tctccaccga tgtccattgt acgaacaact acaggttttc cttccatacc ttctaataca
    32701 gctttgtaag cttcatattg gtcatcttct gttgggaagt ctggagaatc catatacagg
    32761 aattcagtac ggtacagacc aactgcttct ccaccattat tatggacacc aactagatct
    32821 tttggtgttc cgatgtttgc agctaattca aaatgcttgc cgtcagctgt gacagtttct
    32881 gcatttttta atttttccca ttctgctttt tgtgctgcgt aatctgcacc tgctttttca
    32941 aattcagctt tttgttcatc tgtaggatcg atgattacat cgccttcgat cccgttgaca
    33001 gccaaaatat cgccttcttt gactttagca gtaatttctt ttgtcccaac gattgctgga
    33061 atttctaaag aacgtgccat gatagcagaa tgtgaagtac gtccaccaat gtctgttaca
    33121 aacgctttta caaaattgcg atctaattgt gctgtatcac ttggagtcaa gtcatgtgca
    33181 acaacgacca cttcttcgtt gatcattgat ggatttggta aagtaacgcc taataagtgc
    33241 gctaaaatac gtttagcaac gtcacgaata tctgcagcac gctcttgcat ataagcatta
    33301 tcttccattg cttcgaacat accgatatac atatccgtta cttcttttag cgctgattca
    33361 gcatttacgc tgttgtcttt aatattttgc ttgatttgac ctaccatttc tggatctgaa
    33421 agaaccatca aatgggcatc aaatacttgc gcttctgctt cacctaagct ttgcgctgct
    33481 ttttcacgaa tttgctgcaa ttcttcagta gatttagcta atgcagcatc caaacgagct
    33541 tcttcagccg cagtatcttc tactgttgcc ttactgaatg ttaaatccgg ttgaactagc
    33601 aggtaagctt ttgcaacggc tacaccgtca ctagcggcaa tcccttttag catttcaacc
    33661 attattcaga taagccttct ttcttcattg tttcaacgat tgctgccatt gcatcagctt
    33721 cgtcagcacc ttctgcagta atagtaacat cagaaccttg acctacacct aaagacataa
    33781 cgcccatgat tgatttcaag tttactgatt tacctttata ctctaagttt acatcagagt
    33841 taaatttgct tgctgtttgt actaatagtg tagctggacg agcgtggatc ccagtttctg
    33901 ctactacgtg aaattctttc ttttccatat taatcggtct cctttaagtg agtgttgttt
    33961 ttatgtgagg gttttctttt ttagtaattc agagaatcct aacaaatgcc accctttcat
    34021 ctgtaaagat taacattttt tttcgttaga tacaacagtt ttcattcaat ttcagataaa
    34081 agtattcaaa ttattccgga ttctttttca tccttttctt cacattttat aacaaacgtg
    34141 tttatttcct ttttcttgtc gctttctctt ctcctgacgt ttatcattct ttcctttgac
    34201 cctctttgtt ttcatatgaa acgaattact tgcttccctt tttattttta gtataataag
    34261 agtcaaaggt caggaatggt caatagagat ttcacctttt ctacctcata aatctcttaa
    34321 aaaactaggg gttattcttt tacctcatga aaaacgagat gtaaaatatg gatgtaccca
    34381 tttttgtgaa aggacgtgaa tgattcatgc tttgtcaaaa ctgcggcaag aatgaggcaa
    34441 cgattcactt gtatgccact gtcaatggtc agcggacaca actcgattac tgtcagagct
    34501 gttatcaaaa aatcaaaaat caacaaaatg gaggtctgac taatatggcc caaaatgatc
    34561 catttggatt tggcagtttg gacgatcttt tccgttccat gtctcgccaa atgcaacagc
    34621 aaggaaatta tgagcaaaca ccaccaacac aatttggcgg aaacaacaac ttcaatggtg
    34681 gtcagccacc tcaaggcaat acagaaggtt tattgggaga atacggaatc aatatcacag
    34741 aacaagcacg acaaggtgat atcgatcctg tgatcggacg cgatgacgaa atcaaacgag
    34801 tcattgaaat tttaaatcgc cgaaccaaga acaatcctgt cttgattgga gaaccaggtg
    34861 ttggtaaaac agcagttgtt gaaggtttag cacaaaaaat cgtagatggt gatgtaccgc
    34921 aaaaattaat ggacaaagaa gtcattcgtt tagatgtcgt atctttagtc caaggtactg
    34981 gtatacgagg acaatttgaa gaacgtatgc aaaaattgat tgaagagatc cgtcaagcag
    35041 aaaatgtgat cctattcata gatgaagttc acgaaatcgt cggtgctggt tctgctggtg
    35101 atggaaatat ggatgctggt aatattttaa aaccagcttt agctcgagga gaattgcaaa
    35161 tggttggtgc tactacctta aatgagtacc gcatcatcga aaaagacgct gctttagaac
    35221 gtcgtatgca acctgtacgg gtagatgaac caactgtcga agaaacgatc agtattttga
    35281 aaggtttgca aaaacgttat gaagactatc atcatgtaaa atatactgat gaggccatcg
    35341 aagcagccgc aactttatcc aatcgttacg tccaagatcg cttcttgccg gataaagcca
    35401 tcgatttgct agatgaaaca ggttctaaga aaaacttgac gatccaaatc gttgatccta
    35461 aaacaatcga gaaaaaactg caagaagcag aagaacaaaa agttttagct tctcgagaag
    35521 aagatttcga aaaagcagct tattatcgcg atcagatcaa taaacttcaa aaaatgaaag
    35581 aacgtcagct cactgaagag gaaacacctg tgattaccga aaaagatatg gaaaaaatcg
    35641 ttgaacaacg gacaggtatt ccagtgggtg aattaaaaga aaaagaacag acacaactga
    35701 aaaacttagc agatgacttg aaagctcatg tcatcggaca agataacgct gtagatcgag
    35761 tagcgaaagc gattcgccga aaccgtgttg gattaaacaa acagaatcgt ccaatcggct
    35821 ccttcttatt tgttggacca actggtgtag gtaaaacaga gcttgcgaaa caacttgcct
    35881 acgaactatt cggttcacaa gattcaatga ttcgtttcga tatgtctgaa tatatggaaa
    35941 aacatagtgt ctctaaattg attggttctc ctccaggtta tgtcggatac gaagaagctg
    36001 gtcaattaac agaaaaagta cggagaaatc cttacagtct tgtcttgtta gatgaagtag
    36061 aaaaagctca tccagatgtt ttgcatatgt tcttgcaaat cttagatgat ggtcgattga
    36121 cagatgcaca aggaagaacg gtcagcttta aagatacgat catcattatg acaagtaatg
    36181 ccggaactgg taaagtagaa gcaaacgttg gttttggtgc ggcacgcgaa ggtgttactc
    36241 gttctgtatt gaaccaatta aacaactact ttacaccaga atttctgaac cgttttgacg
    36301 ggatcatcga attcagtgca ttatcaaaag aaaacttgat gacaatcgtc acactaatgc
    36361 tagacgatgt caaccaaatg ctggcagcac agcaacttca catcgaagtt cctacgaatg
    36421 tcaaagaaaa attagttgac ttaggctatg atccatctat gggtgctcgt cctcttcgac
    36481 gcacgatcca agaacaaatc gaagatggta tcgctgaatt ttatcttgat cacccttcta
    36541 tccatgagtt gaaagcaaaa ctggataaag atggaaaaat catcgttact tctaaaccag
    36601 aacgtttggc taaagaatca gccgaagaaa cggctgaata aatccagttt tatagcgtga
    36661 gacggtattt ctttgagaaa tgccgtctca ttcttttttc agaaaagtca aaatactgtt
    36721 cattttataa aaaagaaatt ataataagag aaacaagcaa ttaaaaatac ataaaagagg
    36781 tgagcgccat gaaattggta aatgtaacaa acagccattc ccgtcttgta ttaaaccagc
    36841 ttgaaaacac tgatgcccat ctagtcaagg tctacacagc cggaaatacc actattgtct
    36901 acactgaagc ccctgaacat aatgaaattc tgctgatcaa tgacaaacgt aaaatccagc
    36961 cgaaagaaat cgaagatgct aaaaattatt tcttagataa aatcaaagac gccgtttacc
    37021 acgaggatga aatcaaagta atcgaattgg caggccttgt tgaaatctcg attccaaaac
    37081 atgaattagg cgctacatta gccgtgtaaa caaattttga acataataat taaagagcgt
    37141 gggacaaaag taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca
    37201 gaagcaactc cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga
    37261 attccagctt atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt
    37321 tttgattttt ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct
    37381 ttatttttaa ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg
    37441 tttttgtccc agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc
    37501 tgtttttttc tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta
    37561 atcatatgta cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat
    37621 atagtaaaaa gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg
    37681 tttttgtttg gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca
    37741 tcaaactttt taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt
    37801 tctcgaataa gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac
    37861 tcatcttctc atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag
    37921 acatgattac ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta
    37981 gctgaccaac agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg
    38041 ctccttcttg aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt
    38101 ttgcagtcac tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt
    38161 ttagttttcc ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga
    38221 tgatatcgcc tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga
    38281 cattgcttaa tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga
    38341 atgttccaga acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg
    38401 cttggatctt gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat
    38461 cttgtgtttt gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct
    38521 gtacaccgaa gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa
    38581 ttttttcttg attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt
    38641 gttcatataa ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca
    38701 attctactaa tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt
    38761 agatatcata aagaccttct agccctttac ccataccgat tggccaattc atcggataag
    38821 attcgatatc taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac
    38881 gatctagttt gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata
    38941 atttctttgt ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca
    39001 cggccatcaa agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga
    39061 tatttactcg tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac
    39121 gttgtttctc gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta
    39181 cggtcccggc ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt
    39241 tcccagcatc cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta
    39301 attttggatt attcataacc taactccatt tcttccattc aattatttat attttctcta
    39361 ggcacagatt gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc
    39421 gtgtagcagt ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc
    39481 ccacccaagc caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca
    39541 ggatagcttt ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca
    39601 gcgaatgaaa aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag
    39661 aaaagacgtg ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat
    39721 cttcttggct cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc
    39781 gcttctgttt cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc
    39841 atttcttcag aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc
    39901 ggaatcatgc ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc
    39961 agatcactgt caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat
    40021 tcgtgttcat cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct
    40081 ccgacgattt cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca
    40141 tctaataaaa tagccatctg attctgcgtc tttttcattt catataacag atcatcaata
    40201 aagaccgttt caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca
    40261 aagccgaatt tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta
    40321 tctttgtctt cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca
    40381 ttttcttcca cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact
    40441 tctcgggcaa ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta
    40501 ttcaatacgc cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct
    40561 tcatcatcaa aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc
    40621 cagacgaagg gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg
    40681 acttcttctg atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat
    40741 acataggtca aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca
    40801 cctaataccg gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg
    40861 ttgaccaaag tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt
    40921 tttaaaagct tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta
    40981 ttgatcgaaa caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg
    41041 atcaataata aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca
    41101 ttctctcctt ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca
    41161 cgttaaaatg gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac
    41221 ctacgaggtc gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt
    41281 gattatatag gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc
    41341 aagcaatccg gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat
    41401 tttcagtgat ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat
    41461 tagcacaacc acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa
    41521 tgcaggtgct agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat
    41581 gaccccaaat aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt
    41641 accaacgaat aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag
    41701 ttgccccaat aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt
    41761 tggcactagt ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat
    41821 tactacggtt gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact
    41881 aaggaattgc tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat
    41941 atctacttcc ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt
    42001 gatgaaatca ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac
    42061 actaagtaaa atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca
    42121 tattcttttg atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag
    42181 aaagcctgca atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa
    42241 aataaagttt atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga
    42301 ccaaaacatt agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct
    42361 tactagtata tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt
    42421 gccatacttt ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc
    42481 atgaaagttg tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc
    42541 aggcatcaag tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat
    42601 gaagcccatt gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta
    42661 cgtcttttgc ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa
    42721 tacagacacc aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat
    42781 caaggctata atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa
    42841 ctaggatata cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg
    42901 aaaaagactt tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa
    42961 atctctcact ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg
    43021 ttataccaaa tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca
    43081 accagaatct tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt
    43141 ttgctgtgca tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc
    43201 ttgatatcca agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa
    43261 gctagattac aataatagga aacccccttt tctctgatca ttgctattac attgaaccag
    43321 tattttttat gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat
    43381 tcagtgacta atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc
    43441 atggtatctc gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca
    43501 aactctcctt cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg
    43561 tgtttgggtg ttcattacac cgacatcata attattatat caataaaaat gagctttgcc
    43621 tagaaaggat tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc
    43681 ttaggaaaaa cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg
    43741 gtaaattctt gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc
    43801 agatgactaa aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc
    43861 tgcttttcaa atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt
    43921 tctggctttg tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc
    43981 attggaaatg tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac
    44041 gctccagaat gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt
    44101 tttgttttta caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg
    44161 atcggacaag tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc
    44221 attgcttggt tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca
    44281 aagattttcc tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact
    44341 actcgcatca cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc
    44401 gcgcctgtcg tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc
    44461 atttccccat caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt
    44521 gagtaataac caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc
    44581 tcttcaattg taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact
    44641 ctggtttgct gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc
    44701 caaggcaggt ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt
    44761 gtttctttat ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat
    44821 gaatcgctgg atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag
    44881 atttcttttt ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac
    44941 taaataatca tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg
    45001 gatcacttct tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc
    45061 tttttggctt tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg
    45121 aacttggtct tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc
    45181 tttttgctgc atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt
    45241 gcgcacataa ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc
    45301 tacgatttta tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc
    45361 tttttccgat cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc
    45421 tccgctactc ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa
    45481 tcgatagcgt actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac
    45541 gcgatagaaa gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct
    45601 cgaacatata ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga
    45661 ataaaccaca gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg
    45721 acaaacggtt cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt
    45781 caaacggttg atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat
    45841 cacgaaagca actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa
    45901 agatcgcgta gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca
    45961 cttagcttat caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa
    46021 attcaaacca gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc
    46081 ttggcattat agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat
    46141 tgaagctggt ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt
    46201 tcaagaacct cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga
    46261 tgcacccatc tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat
    46321 cggtgttaaa actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca
    46381 aaaaaacgca atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca
    46441 aaatgtccag gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg
    46501 aaaagaagcc attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt
    46561 ctttcaactc aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga
    46621 tgtccagcct aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag
    46681 tgtagcaaaa caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga
    46741 tgcaaaaaaa aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc
    46801 agagcaagtt ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga
    46861 tccaccacgt acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa
    46921 aaaacttgtt tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag
    46981 taaaaagttc aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg
    47041 tgaagttgtc gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc
    47101 tgccctgtat caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata
    47161 ctgtacttgt gaccgaagag ttaacaggag gacactattt atttaaaaaa agggttgtga
    47221 catagttttt gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata
    47281 aaatgcattt gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg
    47341 atcctgcgga agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc
    47401 tatttttgtg atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg
    47461 tttggtaatg tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat
    47521 atttaatgtt cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa
    47581 aggctcaaag ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt
    47641 agcttcgata ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc
    47701 tgctgatgtt cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc
    47761 tggaatgcta aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat
    47821 ctttttcatg tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta
    47881 acacaaacat tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat
    47941 gcagattata acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat
    48001 atgatctttt tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa
    48061 ttatcaattt ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt
    48121 aaactaatat tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg
    48181 gtttgtgtta taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc
    48241 ggaaaatatt actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg
    48301 ccgatgtgga ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac
    48361 aacaacaaaa aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat
    48421 tttatatggt ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt
    48481 acacttttag ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg
    48541 gcaatgtggc tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat
    48601 tcaatttatt ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa
    48661 aagtgccacc taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact
    48721 atttttttct agtacccact tgttgttcca tactcattat tctggtcata accataacca
    48781 ttttgttcct gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac
    48841 tgacttgtat cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg
    48901 ttttctgaat aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc
    48961 gaatcgccat cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta
    49021 ggtaatgtat cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga
    49081 agatcatttt ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc
    49141 aactggtctt gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg
    49201 tcatcccaat ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa
    49261 ttgcttacgc catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga
    49321 cgacgttgtc gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa
    49381 cctttttctc cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag
    49441 tcaattttat tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc
    49501 aaattgatcg ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg
    49561 gccatttcga caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct
    49621 acgatattcg tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga
    49681 ttaactgtta ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg
    49741 gtatctaaac ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca
    49801 gaacgtttgg aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct
    49861 tctcccataa atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct
    49921 aacaaggtta atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct
    49981 aaaatattgt ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact
    50041 ttaaaaaaca tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta
    50101 tcataccata ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat
    50161 ctttttttat gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg
    50221 cagtaaaatg atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga
    50281 ttatcattcg atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt
    50341 ctattcgttt tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc
    50401 attaccatca tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt
    50461 aaagtaatag aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt
    50521 tattcaacat ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc
    50581 ttgcttgata attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaaat
    50641 ctaaaaactt cataaataga caaaaagaca cgactctcta agaagtcgtg tctttattca
    50701 acaaattatt ataatttagt cacttcagca gcttgaggtc cgcgtgcacc ttcaacaatc
    50761 gtgaattcta cttcttgacc ttcttctagg ctcttgaagc cgtctccttg aattgctgag
    50821 aaatgaacaa atacgtcatc tccgccgtct actgtaataa acccaaatcc tttttcattg
    50881 ttgaaccatt taaccgttcc gtgttccata aatgtatatc ctccaaaaaa gttcttgcaa
    50941 gtaaccttgc aagaacatta tacccaattt agaaaacgct agcaagcttt cgctctttta
    51001 ttttccaaat tatttttaag actgatatga cggaggaaat ggttattttg ctgcttcgaa
    51061 acgtttgttt acttcatccc aattaataac attccagaat gctgcaatat aatctggtcg
    51121 gacattttta tatttcaaat aataagcatg ttcccaaacg tccaaaccta gaattggtgt
    51181 ctttccttcc atcaatggag aatcttgatt tgcagtagag gtaatagcta attttccatt
    51241 ttccattaca agccaagccc atccagaacc aaatcgtcca gcggctgctt ttttgaattc
    51301 ttctttaaaa gaagaaaaat caccaaaagc ttcattaatc gcttctttta tttctcctgt
    51361 aggttcgcca ccagcatttg gtgccatgat ttcccagaaa aatgaatggt tagcatgtcc
    51421 gccaccattg ttacgtacag ctgtcttgat atctgttgga atagcgtcca tatcagataa
    51481 taattcttct attgtttttt cgcctaattc tgggtatttc tcaattgctg aatttaaatt
    51541 cgtcacataa gtattgtgat gcttatcatg atgcagatgc atcgtttctt cgtcaatata
    51601 aggttccaat gcgtcatatg cataaggtag atctggtaat gtgtaagtca taaaaaaatt
    51661 cctcctcaat gttttcttaa taatgtctac attacaaaga gtaacaaaga gaaggaaatt
    51721 cttcaattgt tatgcctagt cgtctttttc actttgacct acttcttctt caaaaacctc
    51781 agtttcttta aaaataaaca acttgctgaa aatatagttc gcaaggataa caataatttg
    51841 agtgatgatt ttcgccacat actcattgct gttcataaca ttgatcaaca ataccattgc
    51901 ccccatgtcc aatccgtaag aaaggatacg gtagaagaag aacttaccgc attcaataag
    51961 tgcatgtgta aaattcggtg attttgaatg gaatacccaa agtttgttcg ttacaaaagc
    52021 aaacaataca gaacaaaacc acgaaataga attggataag gccatactta aatcaaaata
    52081 ttggcgtgcg agagcaaaac taacaaaatt tacaatcgta gccaaaccac caaaaaagag
    52141 atagactagt atctcccaat atccttttgc ttctaaatat ccttttaact gtcgatactg
    52201 cttcatgagc caacctacct tattaaaaat tcttatttat catactctat atttcaataa
    52261 ctttcatctt tatttaaaaa aattaatttt ttttgatcct ttgcctttgt ctctgcttgg
    52321 atcgtcacat gtgtaatacc atattttaat tttaataaag aaattatacg aggatatatc
    52381 ttttcaatct cgcttagtag ctgatcttca aaatcaatat gtccgtcgaa aataattatc
    52441 ttttcgctat actgccaaat atggacatga tgaacatcct ttaccccatc gattgcttca
    52501 atttcttgtt ccattttttc atagtcgata gcaggtgcac tttgtatcaa aatagcggca
    52561 gcttttttga tcaccattat cgcttctatc aatatatata tcgaaatgat cagtgtaata
    52621 actggatcga tccagtagat atcgaaaaaa cggatcaaaa ttgctccgat aatcacactt
    52681 accgaagaca gtgtatcact taacaaatgc aaataactag attttatatt caaactttca
    52741 tctgcttctt gtcgtaataa taatactgag aacaaattcg cgagcaatcc aataactgct
    52801 actgttagca tcaaatgact atttatcttt tctggtgaag tgaaccgctt gaatgcttca
    52861 acggttaaaa acaaggataa tatgatcaat atgaatgagt tgatgaaagc actcaatatt
    52921 tctaaacgct ggtagccata cgtacgtttt ttatttgctt cttttcgggc cattttttgt
    52981 gccccgtaag aaaaaataat tgccaatgta tcactaaggt tatggaaagc atctgaaaca
    53041 agagacaaac tccctgacat aatccctcca ataaattctg ataaagtgat caccgcattc
    53101 aaaaccacta ctccaaatag tttttttgat gatctctgtg gctgtgtagg cactattcct
    53161 tcctccattt tatttatatt ggatagtctt tagacaagaa taacattttt ttgatatttc
    53221 accaatcatt cagctgtttc cttaaagcac ttgtatttca cttgatactt cgctagaatt
    53281 gcaagtgatg acactactag atgaggagta cttatgacaa caaaacaatt aattatcagt
    53341 tcctttatac gattcaaaga cctaaaggag gcgagaaatg tcccattttg gaaagccatt
    53401 gtctatcttt tagttttgag tataattatg gctttgccaa tctcttttca agtttttcaa
    53461 gtcttaaaca acattcaatt ggatgggcaa aagattgcta ctcgcattcc tgattttaca
    53521 atccaaaacg ggcagcttca aaccgaagaa aaagaaggat tcatttacca aacaaactcc
    53581 attatcttca catttgatcc agagggaaaa cgaacagaac aggacatctc tactgatttg
    53641 atggggaatt ttgttagtgt cgggatgtta aaaaacaaac ttatcatagc tcttcctaat
    53701 acaggcacga cttctgcttt gttgaacaat aaccaattag aacttcccta caccaatgaa
    53761 tctttaaaaa acttaacagg taagcagctc cgttcttttt taagtgaagc atctatacca
    53821 ctttggataa aagtcctgac atttatattt tctatttatc ctagttttct gaatctgctg
    53881 atcactttgc tatttaccaa cattgctgct tttctctatg cacgctttcg actaacaaaa
    53941 gctacttttc ttgattgttt aaaaacattg atctattcaa tttcattgcc tactataatt
    54001 gcaacaatct tgatggtctt tcttccttct tttgacacta gcgccttcat tgcttttgca
    54061 ggaatcttta tttttgctca agctgtcaaa ggatgggcaa aaatatcgat caattaagaa
    54121 ataaagacaa ctcgttattt ctacttcaat agaccctttt agaggttgtg acattttttt
    54181 gtcacagccc cttttttatt tgaaaaatat ttctttctca aaaaacaagc aaggcgcttc
    54241 aaagttcttc ttgtatgcgc tacacttaga gtaaagaaag gcgggaaatt aactatgtca
    54301 gaaagaatca tttatgcaga tcgtccattt cgtgatgaat ttatcgaaga aatccatact
    54361 atagcgcctg gttatatctt taaaacagaa ttacaaccag aggatctaca aaatgtagag
    54421 atcagtttgg gctggaactc agactaccaa gaaaaactat tagcctcttc taccttgaaa
    54481 tgggtccaat ctatctcagc tggtgttgat cagctacccc ttgagacttt ttcaaagaaa
    54541 catattttac tttcaaatgg tagtggcatc cacagtgaat cgattacgga gcatgtctta
    54601 ggaatcatcc ttgggtattc tcgtggtctt tttcaagcac aaaaggcaca gagtgacatg
    54661 aaatggttag gttcatcggt ccattaccaa tctatccaag ggaaaaaaat actaatcatt
    54721 ggaactggcc atattggaaa aatgattgca aaaaaatgca aagcattaga catgaactgc
    54781 tatggaatca atacatccgg tcatccagca gaaggaatgg aaaagacttt ttctttaaat
    54841 caactaaagg aagttcttcc tgaagtagat ttcgtagtca atatcttacc tctaacggag
    54901 gaaacaactg ggctctttga tcagcatatg tttgaacact ttgatccaaa atctgtattc
    54961 atcaatgttg gccgtggtgc ttctgttaag acacaagatc tggtgcaggc tttaaataac
    55021 cagcaacttt cctttgcagc attagacgtt tttgaggaag agcctcttcc acaagatcat
    55081 cctctttgga aaatggacaa tgtactgatt acttcccaca ttgcaggttt gacacctgat
    55141 tttcaaaaga aattaatggc tattttttta accaatctga aaagctactt tgccacccat
    55201 gagcttcaaa ccaatcaagt aaaattgtct gcaggatatt aatagctgaa aacaatattt
    55261 tcaaaagaaa aaagagaagg tgacaaaaat tgtgtcaccc tctctttttt tattgttttt
    55321 taaagtgata ggttggctcc tccaggttgg gatcataatc aacaagtaaa tcatatcctt
    55381 taaagaacca ttcatctgct tcctcgataa aaaaaagtgt cccatcaatt tccactttct
    55441 ttacaggatg ttctggctgt tcaactgaca ttccaatcga aaaaccatca tgaacctctg
    55501 ttttgccgta gacttttcca aaaaaacgta ttccgtaagt ttctggcaga tcaatttctg
    55561 agtcaaacca cttttgtgct tttggcgtta ccgttaattt catcccaaca acctactttc
    55621 tcttttcttt ctattgattc atcttatcgt ctagaatatc cacatcgcct gtctctccaa
    55681 taaccagtag attatcattt tcacgaacat attcatctgc tgcaggagaa gcgataaccg
    55741 tttgatctac tcttcgtatg gcgactactg ttaagtcaaa acgttgcctg aaatttaatt
    55801 cagctaatgt tttgttgaaa aatttaggat tggagactcg gatttctgct aaagaatatt
    55861 tatctgacaa ctctaggtaa tctaaaatat tctttgacac taaattatgc gcaatcctta
    55921 ttcccatgtc tcgctcggga tggacgacgc gatcagctcc gatcttttca agtactctgg
    55981 catgatactc attttgggct tttgctaaaa tatttggtac gcccatttcc tttaccatca
    56041 gagtaactaa gatactggct tgaatatctt ctccaatagc gacaattaca tgatcgaaat
    56101 ttcttatgcc taatgatcga agtgtcattt catcctgtgc atttgccaca acagcatgag
    56161 tggctatatt catatattca ttgacccgat cttcattact atcaatagcc agtacttctt
    56221 gaccagcttc gatcagtgtt cggcagatac ttccgccaaa tcgtccaaga cctacaattg
    56281 caaaattttg tttcaccgtt ttcctccttt agtatcttct tttctcagta taacaaagcc
    56341 tttacaaaaa caaaagcaag catcattatt gtaaaaaagc caagaaaaat aatagttatt
    56401 ttctcagctt ttgattatcc tctttatcat cgtttttatt tcaccaaacc atgtttgaat
    56461 gcatagatag cggcttgtgt acggtcttcc acttctagct tagccaatat attggaaaca
    56521 tgtgttttta ctgttttcag tgtaataaac aattcgtccg ctatttcctg attacttttt
    56581 ccttcagaaa tcagcattaa aatttcattt tcccgattcg ttagttcttc atgtaataca
    56641 ggctcatttc gccgactcat tttttccatc atttttgttg tcacttctgg ttctaatact
    56701 cgctcgccac gttgcgttgc ccttatagca tcagcaattt catgtgcggt agaggtcttc
    56761 aacaaatacc ctgctgcacc tgcttcaatg gcaggataaa ctttttcgtc atcaataaaa
    56821 ctggttacga taatgatttt agcttctggc caatctttta agattgcttt tgttgattcg
    56881 ataccatcca tttcttccat gactaagtcc attaaaatga cgtccggtcg aagtgtcatc
    56941 gccttctcat agccttgtcg tccattttca gcttctccaa ttacttcaat gtcttcttga
    57001 atagataaat aaaaagagac gcctaagcgc accatttcat ggtcatctac taataaaact
    57061 tttatcatcc ttatctatgc ctccttcatc aaagggacct tgatttctac acttgtacct
    57121 tgacctttaa aactaatgat ttttactgtt ccaccaatac cagctactcg ttctttgata
    57181 ttgttcaatc cataacttcc cgttttcgtt tcattcatat taaaccctgt tccgtcgtca
    57241 ataatacgta acaaaagatt attgtctatt ttgtgcaaat atacctctaa ttcattggct
    57301 ttagcatgtc ttaatgtatt tgataacaat tcttgaacga ttcggaacaa gtgatcctca
    57361 atggaactag atagttttac atcttctaca tcccatttca gcgaaatctg gattttattt
    57421 tgcaattcct tcaataactg ctcgatacct tgctttaaac ttttctcttc taaattgact
    57481 ggacgtagat gaagaagcag cgcacgcatc tcagactggg aagcgttgat gatctctgct
    57541 accattttca actgcttgcg aaacatttct ggtgtctcgc ttttttctgc ttgctccgtc
    57601 aatgccgaca tcatcatcat tgctgcaaac aattgttgcg aaactgaatc atgcagctca
    57661 cgggctaatc gatgtctttc taattctaaa atttcttctt tggtttgtcc atctacatat
    57721 tggggacggc tcgttacaat ttgtaattca ctagatactt caatcatttt ttcttttatc
    57781 ttagtgattt ccttatcaat atctttgatg tataaatcgt ccgatgcact tgggatcgga
    57841 agaagcaaca atttggattc ataattgcca gaagaaagtg cacgcagctt ttcttcgatt
    57901 ttcccgtatt ttgtcttttg aataagtgat aataatagaa agacaattaa tcctacacct
    57961 aaggaaatgg ctaacaaatg gaagataagc ggaacatata ataaacgtgc acgcagtaat
    58021 tctccccacc aatgactttg attgctggca taaaaataag tgaaaagtga aaatagaata
    58081 ataaggaaag ccgcaatccc cgaataaaca gctagcatcg ctctggatat ttttcccatc
    58141 atattcgtat cacctcgaca tctccaatca aggtattagt aataatcttc aatctacgag
    58201 ggttttcatc ataatcactg ctgtagattt tgatttgttc atttttcaaa gaaaattgct
    58261 cttcttcaaa caagacattt cctactaatg tcgcatgctc taatcggatg gctacgccca
    58321 aaggtactaa gatccgtgtt ctgcctatcc cttttcttac aatcacaata ttatcatctt
    58381 ttggcaaaag cgtattgccc aaatctatga tagtatcacc agaaatgacg gcgatgttga
    58441 tatcgtccca ttcatagacg tcgtttccaa tacgttggtt accgaataat tgctgtcttt
    58501 tccgctcatt attatgtgtt tttaattgct ctgtttggat catcatgatc tgtttctttc
    58561 gccaaaaagc atttttggtt aaatctatcc ctgaaatctc tacacctttc agaccaataa
    58621 ataaaacggc aaatacagcc atcatccata aagcaggact gttgactaag ctaaaaaaaa
    58681 tgaccaaact tcctaatatc aattgaaaat tttgaaattt agtacgagga tgtttgcgca
    58741 tagctagata tatattgaaa ataccgaata tcactaaaag caaaagtcca gtattgttta
    58801 cgatttgcca aacagcaaat aacagcagta gtgcttcaac taccacaaaa aaacgccaag
    58861 aactattcat cgctctttct ccctcctgac acattctcat ttcatcatac ctattttttt
    58921 aactgttggc tataggactt tagatgtaag atcgtttgtt gaaatctaaa atacacaaag
    58981 agaaaaagat ctagagtgta tcatcagtaa gatgaactct ctagatcttt cagtcagact
    59041 acgcttgttc tactttgacg attttaacta acatatcgcc acctggagta gcaatagtta
    59101 cttcatcatt tttacgtttg ccaatcaatg cttgcgcaat aggagaatca ttggaaattt
    59161 tgccagaaaa cggatctgct tcagcgcttc cgacaatcgt gtactcttct tcttctccat
    59221 ctggtagttc gatgaatgta actgttttac caattgatac ctcatctgca tctacaccgt
    59281 cgttatcgat gatttgagca aaacgaatca tattttcaat tgttgtgatt cttccttcaa
    59341 caaatgcttg ttcatctttc gctgattcat attcagagtt ttcggaaaga tctccgaaac
    59401 cgcgggcaat tttgattcgt tcaatgattt ctccgcgttt gactgttttt agttcttcta
    59461 attctttttc taatttttct ttaccttcta gagtcattgg ataaactttc tctaccatgt
    59521 gtaacgtctc cttttttcga taaaataccg caaaaggtaa tcttttgagg aatatagtcc
    59581 aaaaaagatt accacgcttt tcttcaaatg taaatgtttt tctaaaaatg atcaatgtct
    59641 agagcctgtt tttctaagaa ttatttacat atttttccac taattccata tgttcttcat
    59701 aagttttagc gaaataaaca tttccagtgc tcgtatctgc tacgaaataa taatagtcat
    59761 tttctgctgg ttctaatact gccttgattg cctcttcgct tggattgtca aaaggtccag
    59821 gtccatagcc ggtattggta tacaaattat atggtgaatc tacagctgta tcttcatacg
    59881 tcactaattc tttgtgttca cctaatgcgt ataaaacaga gatatctgac tgaagtggca
    59941 tatttgcttt gattcggtta aagaagactt gtgcaatgtt tttacgatca ttttctttta
    60001 cgccttcttt ttcaactaga gaagctagag ttaaaacttc ttgtacagtc aaatttttct
    60061 gcttgatagc tgaataatag ttttgcatga ccgtattcgt cttgttcacc atttcaatca
    60121 ctagatcctt aagcgaagta ctcgtgtaat aatcatatgt ggctgggaat aagtaacctt
    60181 ccaaacggta ttttgtgttc tcagctttag atgcactttc caacagttct gggaattttt
    60241 ggtgcaactc gttaaagaaa gtctcatcat tcactaaatc taaaaattct ttcttgtctt
    60301 taccagttac cttcgctacc cgttcagcaa tctgatcgat atcgtaccct tctggaatgg
    60361 caattttccc atctgcaact tttgttggct cagaagtacc gccttcttgc aactgtttgc
    60421 caatctcgtc aagagtcata ttaggcgcta actgataata gccagcttga aagccagtta
    60481 aatttttaaa ttttgtataa taattgaaaa caatcccgct tttaataata ttgtccttct
    60541 ccaaaatctc accaatctgc ttgttagaag agccactcgg gatctcgact tggactaatt
    60601 ggtcatctga tttatctaaa ggcttcaacc cgctatctac ataacgatac acggtaaatc
    60661 caagaaatcc gccaataatc aataatgtaa gagcaatcac taaaatgatc ttcctcacaa
    60721 tcttatcttc ttttttacgc agatttctcc gcttgtcgat tatatctgct gtagctgcct
    60781 tactggcttc ttttttatct ttacttgggt gttgtttgtt tcctgacaaa acaactcctc
    60841 cttactatca agttcgtaac tttattcatt atacatgata tttgaattgg cgtgaatgat
    60901 tttatttaaa tattct
//
LOCUS       DAMEEU010000007        56348 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.007, whole genome shotgun sequence.
ACCESSION   DAMEEU010000007 DAMEEU010000000
VERSION     DAMEEU010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 56348)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56348)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56348
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.007"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            96..269
                     /locus_tag="PB779_000463"
     CDS             96..269
                     /locus_tag="PB779_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738010.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
     gene            complement(335..943)
                     /locus_tag="PB779_000464"
     CDS             complement(335..943)
                     /locus_tag="PB779_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HDE0738011.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(949..1977)
                     /gene="vanB"
                     /locus_tag="PB779_000465"
     CDS             complement(949..1977)
                     /gene="vanB"
                     /locus_tag="PB779_000465"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HDE0738012.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAVCMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYLRMVAAAGITLPALIDS
                     LITLALKR"
     gene            complement(1970..2941)
                     /locus_tag="PB779_000466"
     CDS             complement(1970..2941)
                     /locus_tag="PB779_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HDE0738013.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            complement(2938..3765)
                     /gene="vanW"
                     /locus_tag="PB779_000467"
     CDS             complement(2938..3765)
                     /gene="vanW"
                     /locus_tag="PB779_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HDE0738014.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            complement(3783..4589)
                     /locus_tag="PB779_000468"
     CDS             complement(3783..4589)
                     /locus_tag="PB779_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HDE0738015.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            complement(4760..6103)
                     /gene="vanS"
                     /locus_tag="PB779_000469"
     CDS             complement(4760..6103)
                     /gene="vanS"
                     /locus_tag="PB779_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HDE0738016.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            complement(6106..6765)
                     /gene="vanR"
                     /locus_tag="PB779_000470"
     CDS             complement(6106..6765)
                     /gene="vanR"
                     /locus_tag="PB779_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HDE0738017.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            complement(7383..7550)
                     /locus_tag="PB779_000471"
     CDS             complement(7383..7550)
                     /locus_tag="PB779_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738018.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            complement(7708..7893)
                     /locus_tag="PB779_000472"
     CDS             complement(7708..7893)
                     /locus_tag="PB779_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDE0738019.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            8038..8409
                     /locus_tag="PB779_000473"
     CDS             8038..8409
                     /locus_tag="PB779_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0738020.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            8667..8996
                     /gene="mobC"
                     /locus_tag="PB779_000474"
     CDS             8667..8996
                     /gene="mobC"
                     /locus_tag="PB779_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDE0738021.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            8957..10285
                     /locus_tag="PB779_000475"
     CDS             8957..10285
                     /locus_tag="PB779_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDE0738022.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            10267..10653
                     /locus_tag="PB779_000476"
     CDS             10267..10653
                     /locus_tag="PB779_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDE0738023.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            10836..11072
                     /locus_tag="PB779_000477"
     CDS             10836..11072
                     /locus_tag="PB779_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738024.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(11372..11575)
                     /locus_tag="PB779_000478"
     CDS             complement(11372..11575)
                     /locus_tag="PB779_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HDE0738025.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(11579..12523)
                     /locus_tag="PB779_000479"
     CDS             complement(11579..12523)
                     /locus_tag="PB779_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738026.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            complement(12524..16444)
                     /locus_tag="PB779_000480"
     CDS             complement(12524..16444)
                     /locus_tag="PB779_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HDE0738027.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            complement(16593..18674)
                     /locus_tag="PB779_000481"
     CDS             complement(16593..18674)
                     /locus_tag="PB779_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDE0738028.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            complement(18671..19900)
                     /locus_tag="PB779_000482"
     CDS             complement(18671..19900)
                     /locus_tag="PB779_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDE0738029.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            complement(19890..20141)
                     /locus_tag="PB779_000483"
     CDS             complement(19890..20141)
                     /locus_tag="PB779_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDE0738030.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            complement(20164..22155)
                     /locus_tag="PB779_000484"
     CDS             complement(20164..22155)
                     /locus_tag="PB779_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDE0738031.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            complement(22187..24586)
                     /locus_tag="PB779_000485"
     CDS             complement(22187..24586)
                     /locus_tag="PB779_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDE0738032.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            complement(24516..24938)
                     /locus_tag="PB779_000486"
     CDS             complement(24516..24938)
                     /locus_tag="PB779_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDE0738033.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            complement(24952..25488)
                     /locus_tag="PB779_000487"
     CDS             complement(24952..25488)
                     /locus_tag="PB779_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HDE0738034.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            complement(25525..26388)
                     /locus_tag="PB779_000488"
     CDS             complement(25525..26388)
                     /locus_tag="PB779_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738035.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            complement(26480..26695)
                     /locus_tag="PB779_000489"
     CDS             complement(26480..26695)
                     /locus_tag="PB779_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDE0738036.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            complement(26772..28580)
                     /locus_tag="PB779_000490"
     CDS             complement(26772..28580)
                     /locus_tag="PB779_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDE0738037.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            complement(28577..29053)
                     /locus_tag="PB779_000491"
     CDS             complement(28577..29053)
                     /locus_tag="PB779_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDE0738038.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            complement(29128..29340)
                     /locus_tag="PB779_000492"
     CDS             complement(29128..29340)
                     /locus_tag="PB779_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDE0738039.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            complement(29362..30327)
                     /locus_tag="PB779_000493"
     CDS             complement(29362..30327)
                     /locus_tag="PB779_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738040.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            complement(30373..30561)
                     /locus_tag="PB779_000494"
                     /pseudo
     CDS             complement(30373..30561)
                     /locus_tag="PB779_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(30757..31239)
                     /locus_tag="PB779_000495"
     CDS             complement(30757..31239)
                     /locus_tag="PB779_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738041.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLYPENFRLSLKAPEIRAFRRI
                     "
     gene            complement(31349..33208)
                     /locus_tag="PB779_000496"
     CDS             complement(31349..33208)
                     /locus_tag="PB779_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDE0738042.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(33326..34486)
                     /locus_tag="PB779_000497"
     CDS             complement(33326..34486)
                     /locus_tag="PB779_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDE0738043.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            complement(34793..36217)
                     /gene="araA"
                     /locus_tag="PB779_000498"
     CDS             complement(34793..36217)
                     /gene="araA"
                     /locus_tag="PB779_000498"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDE0738044.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(36233..36931)
                     /locus_tag="PB779_000499"
     CDS             complement(36233..36931)
                     /locus_tag="PB779_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDE0738045.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(36888..38549)
                     /locus_tag="PB779_000500"
     CDS             complement(36888..38549)
                     /locus_tag="PB779_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDE0738046.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            38767..40167
                     /locus_tag="PB779_000501"
     CDS             38767..40167
                     /locus_tag="PB779_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HDE0738047.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(40419..41498)
                     /locus_tag="PB779_000502"
     CDS             complement(40419..41498)
                     /locus_tag="PB779_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0738048.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(41584..42543)
                     /locus_tag="PB779_000503"
     CDS             complement(41584..42543)
                     /locus_tag="PB779_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDE0738049.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(42555..44066)
                     /locus_tag="PB779_000504"
     CDS             complement(42555..44066)
                     /locus_tag="PB779_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDE0738050.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(44088..44652)
                     /locus_tag="PB779_000505"
                     /pseudo
     CDS             complement(44088..44652)
                     /locus_tag="PB779_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
     gene            complement(44658..45521)
                     /locus_tag="PB779_000506"
     CDS             complement(44658..45521)
                     /locus_tag="PB779_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0738051.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(45535..46431)
                     /locus_tag="PB779_000507"
     CDS             complement(45535..46431)
                     /locus_tag="PB779_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738052.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(46606..47895)
                     /locus_tag="PB779_000508"
     CDS             complement(46606..47895)
                     /locus_tag="PB779_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0738053.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(47867..49384)
                     /locus_tag="PB779_000509"
     CDS             complement(47867..49384)
                     /locus_tag="PB779_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HDE0738054.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            49582..50472
                     /locus_tag="PB779_000510"
     CDS             49582..50472
                     /locus_tag="PB779_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HDE0738055.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(50545..51369)
                     /gene="nadE"
                     /locus_tag="PB779_000511"
     CDS             complement(50545..51369)
                     /gene="nadE"
                     /locus_tag="PB779_000511"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HDE0738056.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(51381..52853)
                     /locus_tag="PB779_000512"
     CDS             complement(51381..52853)
                     /locus_tag="PB779_000512"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HDE0738057.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(53490..53852)
                     /locus_tag="PB779_000513"
     CDS             complement(53490..53852)
                     /locus_tag="PB779_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HDE0738058.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            54075..54827
                     /locus_tag="PB779_000514"
     CDS             54075..54827
                     /locus_tag="PB779_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDE0738059.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(54967..55890)
                     /locus_tag="PB779_000515"
     CDS             complement(54967..55890)
                     /locus_tag="PB779_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0738060.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(55905..56177)
                     /locus_tag="PB779_000516"
     CDS             complement(55905..56177)
                     /locus_tag="PB779_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738061.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT        14153 a        13775 c        12265 g        16155 t
ORIGIN      
        1 ggaggggcaa ggcttttttt gagtggtgga agtggattag agcatggcaa tagcaaaaca
       61 gcatagcggc atcctcctat gggccgccac accttttgct gccagaaaag aacggcggcc
      121 ttgatttctc aaaaccgccg ccagcaaaat acaaaatggg cgtgggaaag gtctgcccaa
      181 cagcggtttt tttcttttct gccgctgggc agattgaata ctataatttg caatgtatta
      241 caaaagatgc tttaaccact ttccagtaaa agattgtcca tgaccagcat agattttatc
      301 aaatccaaaa tctgatacaa aaccaatact ttcattatga aacggcaaaa ttaaaatagg
      361 tatcggggta tggctcatca atcaacttat agtgccacca ttcaaagcga taagactgaa
      421 atccgctgct ttccatgatt ttacgcaagc atcttcgatt ttgtgcctct gcatccccta
      481 tcccttttgc tgtatgatgc gaccgttcgt ccataaaatc gaagttactt cccattgaaa
      541 caagttcccc tgtatccagg tggtagagcg taagatcaat tgcgcttcca cggctatggc
      601 tggattgtga ggccacataa ccctttgtaa tcaactcggc tcgctctata ttggggtaaa
      661 atttttcttt tgtgaggttg tcctccggtt gcgctgccca acgcaggaag cagtccaccg
      721 cagttcttgg ccgatatcca tcccataaaa gcaagccata gccaagcgca gccgcatgga
      781 tttgtgcctc gcgcagagca aacgccacgg cctttgtgcc gatgatgcga ttcacctcat
      841 acccatccac cggttttcct gtgaagttat cccatgtggc gtacttggca tcccaacgga
      901 cgccatgcaa catttcatct aaaaacaaaa aaccattttc catacttatc acctctttaa
      961 cgccaatgta atcaggctgt caatcagtgc aggaagcgtg attcctgcgg cggccaccat
     1021 acgtaggtag cggctgtacg atgtaaaacc gggcagggta ttgacctcat ttagaacgat
     1081 gccgccatcc tcctgcaaaa aaagatcaac acgggcaagc cctctgcatc caagcacccg
     1141 atatactttc tttgccgttt cctgcacccg atttcgttcc tcgaccggaa tgtctgcggg
     1201 aactgtaatc atcgcatttt ctgagccttt ttccggctcg ttttcctgat ggatgcggaa
     1261 gataccgtgg ctcagccgga tttgatccac ttcgccgaca atcaaatcat cctcgttccc
     1321 catgaccgca cacccgacct cacagcccga aatcgcttgc tcaattaaga tttttccatc
     1381 atattgtcct gccgcttcta tcgcagcgtt aagttcttcc gtaccgttta ctttggttac
     1441 gccaaaggac gaacctgacc gtgccggctt cacaaagaca gggtaggtaa gcgcacccgc
     1501 ctccggcttg tcacctttat caatcatttg aaattcggga acggcgatgc ccgcattttt
     1561 tgtaagaatg taggccagtg atttgtccat gcaaactgcg gagctttgaa tatcacagcc
     1621 cacatagggg ataccagaca atacaaacag cccctgtatc gcaccatcct ccccgcattt
     1681 gccatgcaaa accgggaaag ccacatcaat acgccgtgtt tcgtattcgc tttctttcat
     1741 gacaagcagc ccatgcgttt tcctatccgg ggagagtatg gcggggagac tgtcggcttc
     1801 ccattccgta catggcttct tgcatagctt ccatacaccg ttttttgtaa ttccgatgta
     1861 gtgcggatcg aatttttccg tatcaatgtt cgcagcaatt tctattgcgg attttaccga
     1921 cacatcatgt tcctccgagc aaccgccgaa gatgattgcg acttttattc tattcatgct
     1981 gtaaactcct ttcaaaattg agacaattcc tgattgtttt ttctgtagta tcctgcagca
     2041 cacgctcagt gtagtacgcc gtatggggtg tgatgatcac attcggcatc cttaaaagct
     2101 gcgacaaaaa gggatggtca agcactttct gcgagcaatc ggtataaaca aactgatcct
     2161 cgccctccaa cacatccagt gccgcaccac ccagctttcc gctttccaac gcctccacca
     2221 gcgccccggt atcgacaagc gctccgcgcc cggtgttgat taaaaatgcg ccttgcttca
     2281 tctctccaat ttgcttctga ccgatcagat ggcgggtatc cgcacaaagc ggcacatgga
     2341 gcgtaacaat atcgctgttt tttagaagct catcaagctg gacataatct gcatccattt
     2401 ttcggctgtt atcataggcc agcacatggc atccaaatcc ccgcagcctt ttgacgaccg
     2461 cttgcccgat atggccggtt ccaataactc ccacagtcat atcccccagt tctttccccc
     2521 ggatacgatc caatctgaaa tcttgttgcg ccacggcgtg catggtgggt tttgcacccc
     2581 gtatggccat cagcatcagc atcaaagcat aatccgcaac gctgtccggc gaatacgcaa
     2641 ccgtgccaac cgagattccc attctctcgg cggcagtcgt atcaatgtga tcgcagccga
     2701 tgctgcgggt agaaatgtat tttaccccga cctttctcag cgcaagaatt gtcgcctcgg
     2761 aaacctcgga cttatggcct acgctaacgc attgattgcc agcggccaat tttgcgttgt
     2821 ctgccgatat cgcatcgcta atcagcgtag ggataatatg aaaatccggc gataaagcgc
     2881 ggaaagcatt tgcctcatcc tgttcgcatc caaaaacagt aatgcccaca ctttttctca
     2941 ttggttctcc tcctgaatat ccacactttc cgggagggga taacagattt tgcatttgtt
     3001 tgtataaagc agcttgcaat ctattatttc cccggtacct aaggcaactt gcatccgttt
     3061 aacctgggca tattcataaa tcccgccact ttcacggaca tactggatac tgccatttgt
     3121 aattttgtat aatgcttggg gctctttgtc ggcggacacc tgaccgatga ttttctcatc
     3181 atctaaggtc acccatattt ggtaggtgca gtcggtatcg tttcgcactt ttaaatcaat
     3241 ccagccctct gaaatggttg catccacccc tttaatctcg tcactgtttg gctctggaaa
     3301 ctcctttact tcgtgacctc tgcgctggat aattgtcaat ggcgtatgca ggaacatcca
     3361 aaatagtaaa ttgctcatct ggcacatacc gccgcccgac atggtggtga gtttaccatt
     3421 ggtcaccgta aggccgtctt tatagggggt atctttgtcc gcatggcgta ccagccacca
     3481 gaaagaaaag gtttcccccg gtcttatcaa taagccgttt aaggtctttg ctgccagctt
     3541 taagttgaac accttgtttt cctggtatat catgtcaaat ccggtattgt ggttgtataa
     3601 tgcgcaatcc gtttcaaaga gcaaatggga aagcgatttt tcccctatcg tctgcgcata
     3661 gcgacagccg tcaaatctca ttcccgcata aaagcacatt tttctctgcg cccgtctcat
     3721 tggaagcagg aacgggaaac gctgtgtcaa tctttttctg tccataacat aacatccttt
     3781 tctcattttt ctggttttaa atattcctca aggcaaaccc cttggttgta catctctgtg
     3841 gcagcttcga tgccaacata tcggtaatgc cacggctcgt tgctcacacc ggttatctct
     3901 gtcttgtctg gtgggtagcg acgaataaaa ccaaaacgat agctgttttc atccagccat
     3961 ctataaacct cgttgcctgt tgaatgaatt ccgtccgcat tgatatccac agcaagacca
     4021 agctgatgct cgctcgttcc cggcacggcc acccaagttt ctgcttccgc tttagcctgt
     4081 gcagaggtgt agcctttcgc cttatattcg gcaatttttt catccataat ttcttgctgt
     4141 ttttctgttg ttcggtatcc ggatgcgaca atcgggtaaa ctccatcagt tcttgcggca
     4201 tcaaacaaat cttgaagata gggagaaatc cgaatatcta tccgctcacc atttgatagt
     4261 tgctcaagct ccacatcgta ctgtgcgggg atggggttct gcctgttcac taaaatcagg
     4321 ctccattcct gttcatctcc ctgttctttg gcggtggcaa gagcgttttc ctccaaattc
     4381 tccactacgt cagtgctgct gcctgtatga gttgcaggga tgggcggtat ctgtgttgcc
     4441 tccaatacgg aagccagtct ccaccccaaa aacagcgtgc agactgtgaa cgaaataatg
     4501 aacgcacata gaaaagcccg cttttccacg gattgtttca tatgccgttt gtgatgatcc
     4561 gcattggaat gatagttgct tttttccatt tgatcgaatg cctcctttgc aataaaacta
     4621 cgatttgtgg ctggtacgat tgttattatg gcaagcgcat ctgtactttc cctgtagcca
     4681 gtctgtagtt ttcctgtagc agcaaaaaaa gaccggcagg gttatacctg tcggtcaaaa
     4741 tcatttaagt tttaaatatt tacaatgttg atgtgagcgg taaatccagc cagaacaaaa
     4801 cgccatccga ggtgttttcc agcgcatact ggaggctcat ggcatccagc gttttttgta
     4861 cgatggcaag tcctaaaccg cttcgcccac tttttctgct tcgcgcctga tcaatgcgat
     4921 agaatggggt gaacagcctt ggaagcgcag tatcatcaat gtgaacgccc atgttcaaaa
     4981 caaaaaggcg gcatttttca gcaccaggct cactccatat ccgtacctcg cctccctgcg
     5041 gcgtgttctg aactgcattc aatatgacat tggatagtgc cttttggagc agcctcggat
     5101 cggacaggac aatttgcccg gctggaatat ctgtgacgaa ccgctggttg tttgcctctg
     5161 ccaaggtttg aaaatcgggc agcaactcgg caaccgtgcg ccctatgtcc aacggttcag
     5221 ctatgggtac gattctccca tcattcaggc tgacaagctc cagtatttcg gaaatgattt
     5281 tgccctgcct atccatcatt ttgatgcatt cgcgcagata cttagaatga tctttgtagt
     5341 caccgatatt ttcaagcatt ccctccaaca gaacgcttgt agccgcgatg ggcgttttta
     5401 gctcatgaga agctgccgca aagaaatatc gctgtgtttc ctccaactca tgttcccttg
     5461 cgatttcatc ctccagcctt gcgatggttt ctttcagcct gacatacatg gaatgcatat
     5521 catgagccag tgcgccaagc tcatcctttc gctccagcgg cggcggtaca tctttcaggt
     5581 ttgccatttt attcgcactg tccgctaagg ctttgatcgg cgttgtcatt tgccgcgcaa
     5641 agatatacgc gcataaaagg ctgaatacaa ccattatcgc aatcataaca attccccgaa
     5701 ttgtcagccc ttgataaagc aatcccacac ctgccttgct ttgagcaaca atcgaaatat
     5761 tatcatctct atgtaccaca taaagaaagt cgggtctaaa actatttgat gtattggcat
     5821 ttggtgtggc atagagtacg cttccctctt tatcttcaat ataaaactca aaggattggt
     5881 tattgtagtg aaacagccct gccacctctt gaatatcaag cctatcgcta ttctgaatca
     5941 gttccaccaa tggctgatag gattttactg tttgctgtaa ttccatcact ctgaaataag
     6001 acacaaattg ctgtgcaaac agtgttgctg ttacaccgac aagcagtagc aggacaatga
     6061 tcgtatagga aaaaacctta atgaaaatcc cttttctttc cattattatg attcctccaa
     6121 tcggtatcct acaccgcgaa tggttttgat gatattttcc ggcagcttgg cccgcaaatt
     6181 tttgatatga gtgtggactg tgctgccatc accctcaaag tcatatcccc atatacgtga
     6241 caaaatgatt tcatgcgtta aggttctgcc tttgttctgc accagcagca aaaggatttc
     6301 aaattctttt cgtgtcaggg gcagctctgt accgtcacaa agtaccgtga aatcctccgg
     6361 cagaagtgtc agcctgccga cacggatttc ctttgccagc gcaccgctgc gccgcagcag
     6421 ggcttccacc cgctttagta aaatctgcat cttgaatggc tttgttacat agtcgtctgc
     6481 ctctgcatca aacgcccgga tttggttttc gtcatccgac agggctgtca tcatcagaat
     6541 gggagtatca tttttcgcac gaaattcacg caaaagttca tgcccgttca taccgggcag
     6601 cataatatca agaataacca gttgataagt gttttcgtaa aacttggtgt atgcctcatt
     6661 tccatctgtg caggcatcca cctgatatcc tgcctcagcc agaaacgccc ttactgtatt
     6721 acagatatga tcatcatcct cgacaagtag aattcgtatc gacataaaaa tccctccatt
     6781 ttaagaagat aacataacag tctgtagttt ccctgtagtt tcaaagcgat ttcttttcgg
     6841 attttaatca tccgtcattg ggatactcgc ttcttttcat ggtgtatgta tctatattat
     6901 tggtttaaac gaattaaatc aagataataa taattaacac cttcttaatg tttgggatgt
     6961 ttcgattaca gcggttgtca aaacatcccg ataatactgg caagcaatgg atcagaatat
     7021 cctttacgga tattctgatc caccacttgc ccgcctgcgg cgttctcgtt ttgcttgttg
     7081 gggacacccc aagcctcagc aaaatgcgcg gcctcttttt tgcgaatgca ccttgcggta
     7141 tggcttttca cacaggcagg gcctgtgtgt actccctccg gtcgctcttg ccgcactccg
     7201 cgcagcagat tcagtcctaa taccgttcaa gacagtagaa aatcagcaag tctatattcc
     7261 tcatatcttc atcatccgtg tccttgcagt tacaggaaat gtaataatcg ccaaatgtaa
     7321 atcccagaat attttcctca aaaagccgta cctccccggt attaaaatca atcaccccat
     7381 actcaaaggc gcattagacc agcagttatc caatgtctgg agacttcacc ataaagaatc
     7441 cagatgccgg ccttttcaat tctaccatat acggctgata cagcagcagc ttcctcgtct
     7501 ttgtttcggg cattttccat ttctgtcatg ataaagtttc gcttcttcat acatccatgt
     7561 gtaaatcttt tctttctgtt tcagatgaga atacttttta tcggtctgga gcagcctgcc
     7621 atctatcatc ttatagtttt tccgtgacaa aataccatgc tttctctctc ttcaaaacca
     7681 tatccaaaat gcgccggttt cattatacta ttcagtaacc gcctttcctt tctttgtacg
     7741 cctgtcaatc ggcttttccg cagttttggg aatgagccag atcgtcgcca tctttacagc
     7801 gccggggatg cgtcccgcag cacaatagta gtttatccat cgtgggggca caccccattt
     7861 ctcgcctgcc tctttcaacg tcatgtagtc catagtacac ctccacaggg tacattataa
     7921 ttcttttgct cgaagaataa aagaaacaaa atgtgaaata taaactttaa gaaaggtgca
     7981 tataccaaca ttccacgggc agagtatgaa atatacaatg taagtgggag gtgcgatatg
     8041 gcgaatattg aagattgtcc cggctttgaa actttcggcg cggatgtgaa agcggcccgg
     8101 caagcaaagc gcgtttcgcg caaagcaatg gcagagaaaa taaatattga ctggcgctat
     8161 cttgccaaca tcgaaaacga cggggccatt cccagtctgc cggttgtcat acagcttatt
     8221 aaagcctgcg ggcttcctgt ggaacgctac tttaacccgg agatcatgcg ggaggaaagc
     8281 gaactgcggc aaagggtcag ccacaagctg aaactctgcc ccgaagaata cctgccgatc
     8341 atcgagggcg cgattgacag cgccatacta attgaaaagc cgaagaagaa tgaaacggag
     8401 gatgtgtaac tggcatcctc tgttttactt ttagcgggag ctgcacagcg tagcttctat
     8461 ttttttgcac ttttttcttt ccagagggct attttgcggg tagtttgggg ctttggaaac
     8521 gtcttgttag tggagaaaca gtaacgtagc aagcataggg agtgtagcca ctcccggaaa
     8581 aacggcctgc cccgtccctg ccgggccgcg tccgttttgc ttgttgggga aatccccaaa
     8641 cccctgaatg gaaaggacgg tgaagcatgg caaacagaaa gcgaaaaatc gtgctgcgcg
     8701 tccctgtgac gccggaggaa cgggctatga ttgaacagaa aatggcgctg ctgcatacga
     8761 agaacttttc agcctacgcc cggaagatgc tcattgacgg ctatatcgtc aacatggaca
     8821 ccagcgacat ccgggcgcag accgccgaga tacagaagat cggcgtcaac gtcaatcaga
     8881 ttgcaaagag gctgaacggt atggggccgg tgtacgcaca ggacatcgag gatataaagg
     8941 gggcgctggc gcagatatgg cagttacaaa gatacatcct atcaagtcaa cgctgaaaaa
     9001 agcccttgac tacatcgaga acccggacaa aactgacggc aagctgctgg tggcctcctt
     9061 tgcctgctct tatgaaacag cggacattga atttgaaatg ctgctggcgc aggcatacca
     9121 aaagggcaat aatctgggcc accacctgat acaatccttt gcccccggcg aagccacgcc
     9181 ggaacaggcc catgagatcg ggaagcagct tgccgaggaa gtgctgcaag ggaaatatcc
     9241 ctatgtgctg actacccata ttgataaggg ccacgtccac aatcacatta ttttctgtgc
     9301 cgtggatatg gtaaatcagc gcaagtacat ttccaacaaa cagagctatg cctatatccg
     9361 gcgcaccagc gacaggctgt gcaaggaaaa cggattgtcc gtggtgaagc ccggccagag
     9421 taagggcaag agctatgccg agtgggacgc ccagcggaaa gggacgagct ggaaagcgaa
     9481 gctcaaagca gccattgacg ccgctatccc gcaggcaaaa gattttgatg atttcctgcg
     9541 gctcatgcag gcgcagggct atgagatcaa gccgggaaag tttatttctt tccgcgctcc
     9601 cggacaggaa cgctttaccc gctgcaagac attgggggaa gcctacaccg aggaagccat
     9661 caaagagcgt atcaaaggcc gcgttatcac cagagcgccc aaagagcgca aggggatttc
     9721 tttgcggatt gatctggaaa acaacattaa ggcccagcag tcggcaggct atgagaggtg
     9781 ggcgaagctc cacaatttga agcaggccgc aaagactttg aatttcctga ctgaacatgg
     9841 gatagacacc tacccggatt tggaaagcaa agtggccgag atcaccgccg ccagcgacga
     9901 ggccgccgct accctcaaag ctatggaaca ccggcttgcg gatatggcgg tgctgataaa
     9961 gaatatttct acctacaagc agctctggcc cgtggctatg gaataccgca atgcagcgga
    10021 taaggcaaaa ttccggcgtg agcatgaaag cacgttgatt ttgtatgaag ctgcggcaaa
    10081 ggccctaaag ggacagggtg tgaaaaagct ccccgatctg tacgccctga aagccgagta
    10141 caagcgattg gccgaggaaa aggaacggct gtatgagaag tacggcgaag cgaaaaagca
    10201 gatgcaggaa tacggcatca tcaagcagaa tgtggacggc attttgcgta tgacgccggg
    10261 aaaggaatgg acgcaagagc tatgagtatt ccacgaatga attaccctca atatcgcaag
    10321 gcccggaagc tgacgcatga gtgctgcaac tattgtgacg gcaactgcct gttgctggac
    10381 gacggcgaag aatgtatttg cgtacagagc atttcctatt cgcttctgtg ccgctggttt
    10441 aaggccgctg tcctcccgct ggatgcggcc ctgtatgccg agatcaccaa agaccgggac
    10501 gaagtgaaac gctgctgtga gtgcggggcc acgttcacgc cgaagtctaa ccgggccaaa
    10561 tactgcgcgg cctgctccaa acggatgcgc cgccgcaaag aggccgagcg ccagcggaaa
    10621 agatactgga aacctacgca cttagagctg taaaagccct tatatttcaa ggcttttccg
    10681 gcatggtcag cggggtatgt gggtgtttta tcctatcccc gccgaagtgc tgttctaaat
    10741 gcgtagaatt taccagcaga aaagcgccgt tttctctggt tccatgcttc cgaatatggt
    10801 atcatagaaa aaatcagtct gacgggggta tcaggatgga cggacaagaa aagctgctgg
    10861 actatgaaac gatcaaagcc gccgttgccg gtgagaggtg ggccacggaa aaagtgttgg
    10921 cccattatgc tgactacatc aacgagcttt ccacggtgga gatcagacag gcaaacggca
    10981 aaaagaagaa agtcattgac gaagatatac ggcagcgcat ttccctgaaa ctgctggaag
    11041 cattgccgag cttcccgctg gaacagagat agacggcaag agggctgcac cctcttacgc
    11101 cgctttgcgg ctatcacctg cacacccctg aaacagatac acccgctgcg cggctatatc
    11161 tgtttcaggg gtctaattat agctgcaacc tacgcattta agggattgaa aaccgcccgc
    11221 tgcaaggctt ctcccgcatg tttgcagggg caagcgaata cttcatccta tccccgacaa
    11281 taccgggttc taaatgcgta ggaataggca aaaagaaaag acgccggacg caagcgacca
    11341 catggccgcc gcgcccggcg tctgctgttc gttattcgtc tgtgaagtgg aacttctggc
    11401 cgtcatagtc ggcatccgtc atgcgttcca gcttggaaag ggtctgctgg gcctgcgccc
    11461 gcatatcccc atccataacc ggcatgacgg cggtgagcct gtttatcgtt ctgcgccggt
    11521 ctgcattgtg gtacatacag atcaggtttt cttcctccac ggtaaagtgc atcattcctt
    11581 atacctccaa ttcattcttt ttggttctgg ccgccgcctt ttttgggctg gcggcctgtt
    11641 tgctgtcgga tagctgcttg cggatagagg gccggggcct gcgaatactc acatcccggc
    11701 gctcgtcccg gttaatcacg gcatacacgc catgcctgcc tttcatcccg gtaaaacaca
    11761 gggatttata gggcagcatg gcaaagagcc ggtcattatc cttggtggaa gcaatcgccg
    11821 caaagtgcgg ggagatctcc accatgaaat gcgttttatt ggggctgtta ggcgcggaca
    11881 gatctttcag gctgtccaca atacgccggg cctcggtttc aatccggctg tcatgcaaag
    11941 cggtgacgtg gactttgaaa tcgccgggga cggcccgccc ccggctgtgc tgctccgtcc
    12001 gtagcgcctc ctgcagcaca gccgggtcat ggggctgggc ctcatagtac aaaaagtttc
    12061 ccaatacccg gtcagggctt ccgtcaaaac gctggctctc cgggatgtca cgggtgccat
    12121 gctcataaaa gagccggttc acactcaccg gctgggcggt ttcaatgacg tgccggaaat
    12181 gctgcggata gtccagctca tagagattgc cccggatagt gccgccctgt gtgccggtca
    12241 gctccaccgc gtaggccagt atcttgtcac gggtctgctc cccgtaaaat ttccatgtgt
    12301 tgtactgtcg ggtgtctttc aggaaaacat cacgttcccg gaaacagtac gtcccggagg
    12361 gccgggacat ccagagcagg gtcttgtctg cggcctgatc gctggcggca tcccgcctga
    12421 taatgtcttt gtcaatgcca aagtcacttt gataaaacgc ggtgttctgc cgcatgatct
    12481 gttccagcgc ggccagaacg tccacatttt caaacttctg catttactct acctccaatc
    12541 cctttgattt ttcccgcgcc ggtggctgct tggcctgttc ggtcttggcc gcgttgagct
    12601 gcgcccggat agagggcttt tctttctccc tgcgggccgc aagctgtaag gcgctgggct
    12661 tttcgccgga aaggggctgg atgcacttga tacggtcagc gacgcggatt gtggtgtcgt
    12721 ttaactgccg ctgccatgcc ccggccttgg gcgaccagcg gaaaccgttg cttttcagct
    12781 cgtcgcgtac agcagcatcc ggcttcccct caaagaagat ttgcaggcgg ttggccaccc
    12841 ggttgatctc cacagtgccg ccgtcaaact cccatcccac ataggccgcc tccttttggc
    12901 gggtcaattc ctcaatgcgg ccctttaacc ggcgtatctc ggcgttattg ttggagagct
    12961 gccaggactg gaacggtttt ttctcatagt gccagcccga cgccatatcc gctttcaggt
    13021 tttcaatgcc tctttcggtc agatgggggc atccgtccag cgtcccatgc ttgcggtagt
    13081 aggcattgac ggccttcatc aactcctgcg acgcttccag cttttccagt ttcttttcca
    13141 gcttggaaac ggcctgcgga tcgtcggcgc tgataccacc catgccggtg ctgcggattt
    13201 tgtcaagcaa gccctgaatg tactgaaatt cctccatgtt gcggtcactg gcggcgttct
    13261 gcttttcttt cgcccgtacc gggaaattgg acggcccggc aatcaggaca gaggggacgc
    13321 gggcggtaat ctcatagccc ttattcatgt tctcggccag cttgcgggcg taggtgtcaa
    13381 ggaggctgtc tatcttttcg tgatactctg gctccacacg ctttttctgg cgctccgcaa
    13441 tttccacggc ctgatcgaca tagtgccggt attccgccgt ggcgctgccg ggccggtagt
    13501 cagaaaagct catggcttcc ttggcgcggc gggcggctcc ctcattgatg ggataatagc
    13561 ggacagccgt ttgcgggggc gcagcctccg ggggttcctc ctgtgtctgg ccggaagcaa
    13621 ctgccacatc ctcaaaagat agctgttcgg gttcctccgg ctgcggttcg ggcggcgtat
    13681 tgttgataat gccgtcaatc atgttttcgt tctgctccgt agacagttcg gcggtacgca
    13741 ggggattttc ccgcaaaaac tccggcactt ccatatagcc gaagctgtct acatagtggg
    13801 cggtgtcctg tccattctgg tgcagcacca ccacgtcgga aacggaaagg ctgtgtcccc
    13861 taaaatctgc cgggtggtcg atgttgaatg tgcggtaaat atcctccaaa gacgtgcttt
    13921 tatccagcgg tgccgtataa acaaggtcat agttggcact gtccacggcc agccctgcgg
    13981 cctgtaaacg ctcgtatggc tcaaaccgat agtcgcgggt ttcctccccg cctcgaagct
    14041 ggtagatgga aaaggtgtcc tgttggggtg cttcatagcc agccgccgcg tattcctcca
    14101 cggtcatacc ggctgcggcg gcctcctgcg cgatctcggc ctgtacctgt gctttgtagt
    14161 cctgcaagct ctggtcgaag tcagccagtt tcggcggctc cggcaactga tactggccct
    14221 gattgagcat ggggcggcac tcctgcacat aagagagaag cgcccccaaa taggccgttt
    14281 cctccggcgt cagggtttcc ccggactgta agcggccctg cgccgtctgt tccatttggg
    14341 caaggctgca atgcagcttc atatagggga caaactcgcc taacagcata tcccgatggg
    14401 ccttgtcctg ctcccagccc tctatgccgg ttgtagcgat tacatgcttt ttccagtttt
    14461 cgtcctgcgc gtaaaattgg tggtagctct ggatatgttc gatcagggaa ccgtccctat
    14521 ctccaaaatc ctgccgcccc tcgtagctgt ccggctcgcc ctgaaagata cagtcaatgc
    14581 ggaacgcggt tttgtcatag cctgcctctg ccggatatgc tgcatccaga cgggcaaaca
    14641 gcgcgtcggc ctcatgcaac ggcatttgct ggccgtcctt tagctggggg ctttcgctcc
    14701 atagcacagt cacaagcggc tcggctgccg gatcaagggc cggggcctgt tcttcctcgg
    14761 cctgcgccgg ggccgctgcc tccggggtaa cgtcaaccgt gacggcctcc tgttcctgcc
    14821 gggcctcgcg ctcctgctga agctgggcaa aatggccgtc gatctcggtt atcaattcgc
    14881 tggccgtggc ccggatggtt tcaagggagg ctttcagctc ggataactcc ctgccgctgc
    14941 tccaatcggc cacatagcca aaagaatagt ccgacgtgtc cagcccgtaa tactggcaga
    15001 cggtataggc cacgctttcg gcctgtacct cgcgggtgct gcggtctggc cgggccgcct
    15061 gttcctcggc gggggcctcc cggtcaatgg cgtggagctt ggcatgggca atctcatgga
    15121 tggcggtctt tagggtctgc aattcgctca tgccctcgtt gatggcaatg cgctgttttg
    15181 cgtagaagca gcggcccttg gccccgtctg aaatcggctc aatgcttatg ggatagggtg
    15241 atgtccgttc cagcgcggca aagaaatcct gatactgctg cacgtcgccg gtaagttcac
    15301 tgatataggg catgggaaaa tccttgccct cggtctggct gatgtcaaag actgtcacca
    15361 ccttaaaggc cggaaccgtc acttcctgtt cttcggtcac gggcttgccg tccgcgccga
    15421 tcacgggctg ctgggtggcc gggtcgattt tctccatctg ctgcttaacc ttgaacgggg
    15481 ccggggccag tatcttaatg cctttctcgc cccgcttcac atggcggtca aattcatcct
    15541 gccacctgtt atagcccgcc acaatcgaac cgccctgcat ggcgatcagc agcgtattgt
    15601 tcagactgta atcgtgcatc ttggacatag cggataagta agccatatag cggctacttt
    15661 caaaaagctc ctgtacgccg gtttccagac ggtcagtaat cactttcatg cgttctttgc
    15721 tgttcatgcc gtccagcatg atcgggataa ccgggggcgg cgctttgtcg gggctttcgg
    15781 atgcctccgg ctgctgggcc tgcggttcct cccggtcagc ttccggctgg gggtagtgca
    15841 tcacccggta ttcctccggc accggctggc cctcatggac gcgctgccat tcgtcgccgc
    15901 ttctcaccag atagccgtac tgggtaaaaa cgccttgttc ctgctgggca atgtggcgtc
    15961 caaactgcgc cgtatcaatc ccggctttcc attcctccgg catatccacc atgccggaac
    16021 ggttcaggta gtagtcgccc aactgtccat cccccctaac gtcgggaaga tgcacatagt
    16081 aatccacatt ttcggtgtag tcgatgatct ggccgatatt ctcaaagccg ccacggggat
    16141 tttgcagggc ggcgttcagc tctgcgatct cggcggcgtc aagctggccc agccgggcgg
    16201 caaggaaatt cagctcgtcc acgtcggcgg ccagcaccat gtcataggga atggcaaggt
    16261 gtctgtcctc cgggcaggaa tacccgttga taaaaaaatc ctgcggattg tcggcagtaa
    16321 tgccaacatc ccgcagggcg gcttgcagcg tttcggttgt ggtgggcaaa tccagccaga
    16381 cgccttgttt gccctgttcc aaaaactgcc ggttatggac ttggatagaa aatacttcgt
    16441 tcacgcggtc actcctttct ctgttctgtt tcaaaaaata gggggttggg gacttcccca
    16501 acaagcaaaa atccccggcc cggcagggac gcggccgggg gattttaccg ggagtgtagc
    16561 cacactccct atgcttgctg tgttactgtc ctttagctcc tgtgttcaat gcggtagttg
    16621 acgtacttgc ccccggtatc agccaaaagc accgtcccgt cgtaggtttt gccggtcttt
    16681 acggaataga ggccctttac cttgactttg ccggttttga gcagcgcagc ggcgatcttc
    16741 ggggtgaacg ctttcttgcg ttcctcaaaa aatcggtcat tcttccacat gacgaactgg
    16801 caggcccggt ttccgcagta gtagtttttc ttgccctcat agacagcctc accacagcgg
    16861 ggacacgtcc cgataggaac acgctcggcc tgaaacaatt tctgcttttc ctcactgata
    16921 caggaatagg tctgcaccag ctcccgcgcc tgcgtctcga tgccgtccat aaattcgtca
    16981 ggatcggcct gccccttggc gatctcggtc agccggtttt cccattcggc agtaagctgg
    17041 ggagaagtaa gcgcctccgg cagcaccaca gccagattga tgccgtcctt ggtgggaatg
    17101 agctgcttgc cttttctctg gacaaagccc atctgcacca gcttttccag aatggcggcg
    17161 cgggtggccg gtgtgcctaa tcccttgcgc tcggcatcct ccggcatatc ctcggccccg
    17221 gcccgttcca tagcggacaa aagcgtatct tcggtgtagg gcttgggcgg cgtggtgaaa
    17281 tgctcggtga cagaggcggc cacgtctgca aaggtctggc cctcgcaaag ctccggcagc
    17341 tcccgcaccg cctcggcgtc ctcgtcggcg tcggtcttta aggaagaacg gaaccggcgt
    17401 tcaatctctt tccagccggg ggaaaggacg gtcttgccct tggcggtaaa ctcctgcccg
    17461 gcacaggtaa atgtggcggt gacggcctca tagatatgcg gcccggccac ggcacataag
    17521 agcttgcagc agatcaggga cagcagcttt ttttcactct cggccagagt gccaaagccc
    17581 tgcttcacaa attcagcggt ggggataatg gcgtggtggt cggacacctt tttgctgttc
    17641 aggatgcggt caaactgcgg ggaaaggttc aggcccttgg caaacggcac cagctcccac
    17701 aggccggaca caaggctttc cacggcgggc agcatatcgt cggtaagata ttgactatcc
    17761 gttctcggat aggtcagcag cttctttaga tacagtgcct gggcatagtc aagggtctgc
    17821 ttggcggtat agccgaaaag ccggttagcc tcccgctgca aggtggtaag gtcatagagc
    17881 ttgggcggct gttccgtctt tttctcccgc gtcacggaaa cgcaaacggc ctgcgctttt
    17941 gcacaagccg ccttgacggt gtttgcctcg gcagcgtcgg aaaagcggct gcttaccgcg
    18001 tccgcgccgc ccgccgtgat atggacgatg tgatatttct ctttcttgaa atcggtaatc
    18061 ttggcgtccc tgtccaccag catttttaag gtcggcgtct ggacgcggcc cacagtcagg
    18121 ttcttgtggt acaggacgga aaaaagccgg gtggcgttaa tgccgatcag ccagtcggcc
    18181 ttggcccggc acagggccga ttgatacagc ggatcatagt cgccgcccgg tttcaggtgg
    18241 gcaaagccgt ccttaatagc actgtcctcc atagaggaaa tccaaaggcg ctcaaagggc
    18301 ttttggcatc ccgccatctg gtagacgaaa cggaaaatca attccccctc gcgcccggcg
    18361 tcggtggcgc acacaaggcc ggtcacgtcg gggcgctgca tcagcgaaca gagaacgtca
    18421 aactgctgtt tcttgtcgtc ggggacgatg tactgccatg tttccgggag aatgggcaaa
    18481 tcctcatagc gccatttttt gaaacgctcg tcatagcgtc cggcgtcggc aaaggacacc
    18541 agatgtccga tgcaccagct caccagatag ccgttcccct ccaaatagcc gtcgtgtttc
    18601 tccgtggccc cgatcacgcc cgcaatgctg cgggccacgc tgggtttttc cgcgattaca
    18661 agtttatatg tcattcctcg tcctcctgtt cactcacaaa atcagcttcc gggtcaaact
    18721 cggtttcggg ttcctcgtcc tccaaatcct cgtcctcccc aaaatcatac tcgcccaaat
    18781 cgtcgctgcc ggtggtttca gccttgggct ttttgaactt gaaatagtaa agggccgcac
    18841 cgccgcccgc cagcgccacc agcaggaaca cgatcaggcc gcccgcgccg cccttgggtt
    18901 cttcctccgg ggcttcgggt tcctccggct ggggttcctg cggctccggg ccgctgcact
    18961 cggtcaggtt ggttttacat accgggcaat tcgtgttcac agccccggcc ttgcatttcg
    19021 tggtacagga gcagacagca gcgggggtga cggtttcccc gtcctccatc agcgtcagca
    19081 gatcggcttc atccacctga tttaagaaat ggacagtttc ttttccctcg tcgtcccggt
    19141 caataatcag ataaaacaca ttgccgtttt tggtttccac ggtgataaac tgcttgccat
    19201 ttttcgcggc gctgccgatg tcgtcaatca gtgacaggtt cccgtccggg gacagggcgg
    19261 cgctggcccc gccgccattg aacagttcca gcagagaagc aatttcctcc gggtcaatgg
    19321 agagggaaaa accgccctcg ccggtagccg ctacttcctt ttcgctgacg gtcatatagt
    19381 cggaatggac atagccgatg cgctccggca agagaatttt aatccagtcg ccgtctgtgc
    19441 cgactacctc aaccgtcgtc ccattgggaa gctgggtgaa cgcggtcttg tcaagccccg
    19501 cgccggtgcg gacattcagc ctgccgccgt tggtggtgac ggtgccggtc tgttcaggtt
    19561 cttttttgtc ggtgccggtg gtgatctgga tgccgtcgtc cgtggcggca atgctcacct
    19621 tggaaccgaa cagcgcggaa aacaggtcgg tgatgtcctt gccggtcaga gggccggtat
    19681 ctttttcggc ctcggtttct gtcccgtccg tggcggtgcc ggtttcgtct gtttcaggct
    19741 ccaaaccgcc cgtagcgggt tcggttgtag cctccggcag cggggccggt gccgggtcat
    19801 tgccgcctgc aagggcggta acgggaaagg ccgtgacgca gagcatcacg gccagaagtg
    19861 cggggagaat acgggaaatc cgtctggtct tattcttcat gggcattgtc ctcctgttca
    19921 tggtaagggg ttgcggcagg ggcggcctgc attgcgccgc tgcgtaagaa cgcggcaaat
    19981 tcctccggct tcatgttcat gccgcgcaca agctggatga tctgcaaatt ctcctgttcg
    20041 gttttctgcg tttccagctc ccgaagctgt ttctgaaact ccgcgatctt agacttggtt
    20101 ttctggatgt ccttttcgat gcggtcaagt ttggttgcca taattgaaag ctcctttctg
    20161 gcgttaaggt aaacgcccgt aactgtaaaa atgggattgc cagtagtttg aagtaaggtt
    20221 cgtgtaggaa atcgggttcc cgcaatgcag catcacattg ttgcccacat acaggccgac
    20281 gtgggacacg ccgggggtgt cgtaggttcc cttgaaaaat acaaggtcgc cgggcttggc
    20341 ctgcgaactg gaaacagggg tgcagatgtt atataggccc tgcgccccca gccgtcccac
    20401 gttccatcca ctatgattga ttacccacga aatgaagccg ctgcaatcaa agctggtgct
    20461 gggagagctg ccgccccaca catagggata accgatatat ttttccgcct ctttgagcat
    20521 ggcggcaaag gtggcatcct ccaaagcctc cgggggtacg tcgtagtagg tcggcggcgt
    20581 cagggtggag gcgttggggt actggctgcc ggaaaacaga tcaggccggt ttcctagcgt
    20641 ggacatatac agggaataga aacttagcgt ttcctcgtcc atgatataga ctggcacatg
    20701 ggacaggtcg aagttttcca gcgtgacgta gcagatgtaa tagtcatacg gcacttggta
    20761 ggtgtctgta tgggtgttgc cctccgcgtc cgtccatgta tcggtttcgg tgcggtaacg
    20821 ggtttctacc acgacgtttt ctgtcaggat atattgcttg tcaaagagca tggacaaatc
    20881 accctgtacc tccccgatgg taaatatccc gtcatggagc gccgacagaa tggaaatcag
    20941 cacatagggg tcatggctga tctcgtcaag gtcaaaatgg tattcgtcat agtcatgggt
    21001 ggcctcgtag ttgtccagat agtcttgcag ctcggcttcc agctccgcgt aggcgtcctc
    21061 ggcggccaac atatcgctat cctcggaaaa gtaagaggac gccgtgatgc cgcttccggc
    21121 gctgccgaac atggcggtgc aggactgtaa gccgccgatg ataagcagca tcaaaagccc
    21181 caacacaagg acggccagcg cccctttcca gtggcgggcc acaaaggagg ccgcccgttc
    21241 actttctttg gctgcggcct tggccgcttt cgtggaggcc ccggctgtct tggccgcgcc
    21301 ctgtgccgcc gcgcctgcgg tctggcccgc tgtccgggcg gccttggcgt actggcgctt
    21361 gatctgctgt ttctgccaga accgggaaat ggggttgctg gccgcctgtg cgatctccgg
    21421 gttatcccgc aaagatttct ggtagaaata ctccgcgttg gcagacaata gcctgcgctc
    21481 ggccttttcc gcgtcccagt agggtttcag cctgtggtgc cggatggtgc tgcggatggc
    21541 ttttccggcc tgccgctcgg caagttcctc ccccttatgg ccgccctcca cacccacgtt
    21601 ttcatgctcg acttcatgga ttttcccgtg gccgaataga aaaacctcgg aaacaggacg
    21661 gcctgccgga ttgggtttca gggagggagg ccccttgtcc tgtttgtcaa agtgcaggac
    21721 ggtctttgct ttgccgcttg cctcgtcaaa gacggtttcc ttgaccggga cgcgcttctt
    21781 ggggatggcg gcgcgggcct tatccagctt atcggcccgt ttgtccgatt ttcggatata
    21841 gggctgtaaa tccgggtcgg cccgttcttc ctccgacagt tggagccggg cggatggccg
    21901 gtgcagggca gcgtccccct cggcggccac agccccggcc tgcttcgcgg ctttcttggc
    21961 cttatggccg tcatggatgg cgtcggcccg ttccagcagc ttatcggcgg tgccgcccgg
    22021 ccccggcgcg gacaaatcct gttcggcctc ccggctggaa atgttctcca cctcgccggt
    22081 ggcctgattt tccagcgtca gcccgtcgcg ggtcatggcc tgcgtcactt tcgccttggc
    22141 tttcagctct ttcatggtgg ttcacctcct ttgtggcgtc gccgggtcat actcccgcca
    22201 cctcgtttaa gcgggtcgtc ataatcttgt aaagctgggt gttgtgcggg atggggttgg
    22261 taaagggcag caccacgttt tcaaagatca aaaggccctc gccgggttcg gaattgtcga
    22321 tgtacttctg ctgttcggtg gacaaattca agcgttccgc aaggattttt ctatccccgg
    22381 acgcctgatt gagcagcgta atgaagtcgc tgttttcaag gatattttca atttccgggg
    22441 aggaaagcag gtctttgacg ttctgggtgg cacctgttgg aatgccgccc catttcctaa
    22501 accgcttcca aatctccgca gaataggccg ccgtctgttc ctctttcaaa agcaaatgga
    22561 actcgtcggc aaaataccat gtggcctttc cttggcttcg gttggccgtg acgcgccccc
    22621 atatctggtc ttggacaatg agcatcccca gctttttgag ctgcttgccc agctccttaa
    22681 tgtcaaagga cacaagccgg ttgccgatgt ccacgttggt acggtggtta aatacgttca
    22741 gggagccgga cacatacagg tcaagggcct gcgccacccg gtcagcctcc gggacatgct
    22801 gatctaacaa cgctttgtgg aggtcggaca ggatcggcat attctccggg cgggggtctg
    22861 ccagataggg ccggtagatc acgcgcacag cccggtctat cacggtcttt tcaatggctt
    22921 ccagcccgtt cttgccgccc atgacaagct cacagaacga cagcacaaag tcggatttca
    22981 gggccagcgg gttatcgtcc tccgaataat tcaggttgat gtccagcggg ttcacaaagt
    23041 ccttgctggt aggcgacagc cggattacct gtccgtggag ccgtttgaca agggggtaat
    23101 attcggcctc cgggtctgaa ataaaaatat cgtcaggcgt cgttaagaac acactgacga
    23161 tctcggattt acagctcatg gatttgccgc tgccgggggt gccgagcttc aaggcattgg
    23221 ggcaacgggc ctgcttcctg tccagcataa tcatgttgcg ggacttggcg ttgatgccgt
    23281 aatacatggc cgcgccgccc tgaaaaagct cctgcgtcac aaaggggacg aacacggcca
    23341 cgctggaagt cgtaaggctg cgctgtatct tgatctgatt gacgcccagc ggcaggctgc
    23401 ttgcaaggcc ctgttcctgc tggtagtcca gccggacaag gggacagtta tgcttttggg
    23461 ccacgcctgc ggcttggaac acgtcgttat tcagcttttg cttggtgtcg gccacgttga
    23521 ggacaaggaa cgtcaactgg aacagccgtt cattgcgggt ctgcaacttt gtcagcagct
    23581 tcttggcgtc ctcgccgtag gtggcaaggt cgctgggaag aatgtccata tcgtaaccgc
    23641 tgcggacggc ctttttctgc tccgcaatct tcatagcgtc aaggtcggta attttgcgct
    23701 tgatggtctt gatcgccttg gtctgttcaa tggcctgcac atggagattg actaaaacac
    23761 cgctttccgt attgaggaag tcggccagca tatcgtccga cagctccggg gacaggattt
    23821 gcaggaaact taccgcgccg tatttgccgc ccatgccgaa tgtctttgca ttgccgaagc
    23881 acagggagga cggggcaata aaatccttgg tggagaggcc ggacggggcc agccacttcc
    23941 agtcaaaatt gaatatctcg ccgtccgggt ggtacacgcc atgcagcagg ttcagccgtt
    24001 cccagccgtc catcacatgg gctacggccc ccatgctctt gaaatagcct aacaggtcaa
    24061 agccgatgcg cttcaatctg gctcgcgccg ctttcacgct ttcggcctcg atggtgaatg
    24121 tcaggtattt ggtctttacc atgccgttgt tgccgtttgc aagctgcttt tgcagaatgc
    24181 cggtgtactc ggcccggatg tcgtcgaagt cgtccccctg cggcgcgatc tcaaagctct
    24241 tggcgtactg caccgggtca actttccgat tgaggaaaga aaactggata tgaatggagg
    24301 cgtccacata gttatacagg tcgcacagtt tttcaaagat agccgtctgc gtgtccggct
    24361 gggcaagctg atagctgatg tccgcaaact caatgcactt ggaaaagacg ccgggcgata
    24421 cccggcacac gccgtccggg tacatgacct cgtaggggat gctctgctgc gccgtgtggg
    24481 gcctgccgtc gcccttatat ttacggatta ccgcgtcaat ttcttttcgc tgggcgcggg
    24541 tcagctttgt tttttcggtt tctcttggga tttccttttt ggacaatggc ctttacctcc
    24601 tgttccatct ggtattgccg cacaagggcg gtgtaggtgt tgtcggtctg atagggacgc
    24661 tcctttggct ggatgaagca gcactggatg atctgcataa tcaccacttc aaggggctgg
    24721 ccgtgacgct cgtacatggc aagcaaaaag cccggcagca tggcaaatac catgagcagg
    24781 gccgccgcgc tgttggtaag atagtcacgg gtgagaaaat ataaggggac gccgatcacc
    24841 agcgccccgg aaaaacagat cagttgccgt ttggtaagcc caaacacaac cttgcttttc
    24901 acatgggtta agtccttggg gacggttaca taagccattt ggcacctcct ttcacgtcag
    24961 gataaggtca cattccacct cgttccccca cacgtcccag ccgggggttt tctgtctggc
    25021 aaacagctcc acgcggggca aatcgcccgc cagctctacg attttttcac gggtcacatc
    25081 cggctttttg ctgtgttgtt caatcgggct gataataaac tgatggacag aggcagaacg
    25141 acgcttcggc ttgccgtgtg ttgccagcag gcagatttcc gcgtttcccc ttgtccagcg
    25201 gcccagcccg taaaaccatg taaggctttt acggttctgt ttcagccata caaaagccac
    25261 ggtcttgaat gaaaagcccc acgctttgat taaccgcaga gcttccggca gcatggggaa
    25321 tgtggcccac aaaaacagca ggcagtcttt ggacgccagc cgttccaccg gcagggcgca
    25381 cagctcgtca atgctcatgg tggaatagtg attttccgct gcgccctgta cgtttttgca
    25441 gtcataccgc cacggcgggt cagcgtaaat gatgttgtac gttgaaataa acaagttcct
    25501 cctgtgtatg cttggatttt gggatcaatg cgccccgaat acggcctttg atatactgcc
    25561 ggtcttgaac aggcagaagc acagcagcac cgtatagccc atacagcccc agattgcgcc
    25621 ggatatgtcg gaagcggaac cgatattctg tatcagcacc gcgtagatac ccaccacaac
    25681 catgattaaa aaggcttgga agcccagcgc cagcagggat ttcagatacc cttggcccat
    25741 gccgcgccat tccgcgttgc ccattgtggc aagggggata ggccccagcg acgtgacaac
    25801 atagatttcc accatgcggc cataggtcac aaggaaaatg cagatggaaa ggatattcat
    25861 ggtgaggccc acaacaaggg tttggaacca cagccccaaa agagcgccca cgctcatagc
    25921 ctccaattgg ctttcaaggt ctggtatcag ggtgttaaaa tcaatggatg tctgcccgat
    25981 aatcacaccg gcgctttgat tgacgacgct ttgggtggcg tcgaatacgc ccatgacgat
    26041 gttccatgtg ttcgttacga tcaggattgc aaacgcggat ttgaatatcc agcggaagaa
    26101 catggagctg tcaaagtcgt gcatattgtt cttttccgtt atcatctgga taagctcata
    26161 gcacatgaca agggcgagta tggccccggc tatggggacg atcacggttt ccgacaggct
    26221 gtgcagcata ttgaaaatac cgctgttcca tgcctgcggg gttcgtccca cgtcggcggc
    26281 gatttctccg actttggcat ttaccgtatc gaacagcccg gacaggttgc ccgtgatacc
    26341 gtccatgagg atgcctttta tccattcttc aatgatttca ctaatcacgg gtagcacctc
    26401 ctttcccgcg ccctcccggt ctggccggga ggacgcggag gcgattagtt aagggtttgg
    26461 acagggacaa aggccaggat cagcccagca gcccggacag caggggaacc agagtgacac
    26521 cgatcagggc cacgccgccg ccagcgacaa gctgcttgac accctgcgat tttgcccccg
    26581 gattgtcctg cccgtatccc tccaacagat tgatgccgcc ccatacgcac agagcgccgc
    26641 ccagtccgat cacgatagtc tgcaaagtag taactgcgga attaaaaaat gccataaatt
    26701 tacctctttc tgccggtttc cggctcataa tgattttttg attttgttgt tggaatgaaa
    26761 aaagccgctg tttattcagc ggcggcgtcc tcgtccgaca ggtcgatttc atacaggtcg
    26821 aatacttcat cctgcgttac cacttgctgc cgtttccggc gcgtgatagt caaaaatctg
    26881 tccacgtcaa aggtattctt cttgtcggcg tcggcaaggt atttgtaccg gggatgcttg
    26941 gtaatatcga atttctccga taaaaacggg cgcacacccc gtagctgcaa gatacacttg
    27001 ccgccgtcca tcacggcaat ttcgtcttgg gacatcaact cctttcctaa tttttgatag
    27061 ttcaatccgt gggacgtttg gcttccccgg ttctcgctgg tgttgaaact gtcaatcgtt
    27121 tctttcccca gcgcatcgga aatctccttg gcatttttgc cgcgcccact aaggaaaagc
    27181 acactatcgc agttatccga aatgatctcg gcggcgtcct tgtaaatcgc ttttagctgc
    27241 gactggctct gcaaaataat agaggccgat atttcacggc ttcgaatggt ggcaatgagt
    27301 ttatcgaaat tgggtatttg gccaatgttg gcaaattcat ccaaaatcag gcgtacatgg
    27361 acaggcagcc gcccgccgta cacatcatca gcccggtcac aaagcaggtt gattagctgg
    27421 ctttggagca tagccagaat gaaattaaag gtcgtgtccg tatcgctcat aatgagatac
    27481 agcaccgtct tttcgtcccc gatggtgtcc agctccattt cgtcgtcctc catcagctcg
    27541 cgtacctccc ggatgtcaaa gggcgcaagt ctggcaccgc atgaaatcag gatggaagaa
    27601 cgggtcttgc ctgcggacag caggaatttc ttgtactggc gcaccgcaaa atggtcgggg
    27661 tctttctgct ccaaacgctc aaacatgaga tcgacggggc tttgaaactc cgggtcgtcc
    27721 tcgcgggctt cactggcgtt tatcatttcc agcagcgttg agaagttcat ttcctccgct
    27781 ggggcctcgt accagatata gccgatcagg gccgaataaa acaaccgttc cgacttcacc
    27841 caaaaatcct ccgctgactt ttccccctcg cccttggtgt tggaaatcag ggtatttacc
    27901 agctttagca cgtccttttc cgaatggatg tagacaaagg ggttgtactt catggacttg
    27961 gaaaagttaa tggtattcag gattttaatg cggtagcccg cctgctggaa catcctgccg
    28021 gtttccagaa ccaaagtgcc tttcggatct gtcaccacaa acgaagtcgg atagtccgtg
    28081 gtcggaaagc attgcatcag gttgggtttc acgaaaaatc tcgttttccc tgaaccgctg
    28141 ccaccgatca ccagcacgtt tttattccgc gctgtcttgg ggtctttggg cctgccggtc
    28201 atggtaagcc gttccgtttg ggtgagcagg atattatttt caaacttggg gtcgatgtaa
    28261 ggcgctatgt ctttggccgt cccccagcgg gcgctgccat actccatgcc tttgcggtat
    28321 ttcttcacgt tcttgctctt gcagtacacc accagccgca cgatcacggc accggcgata
    28381 ccgatacaca ggtcaaacag gtgcaggctt ggcagcgggt tggcaaaagc cgccgcaaaa
    28441 ccatccgcaa aatgcaggag cttccccgac aggtcagcac cagcggccag ccggtacgcc
    28501 tccccgcatt tcgcaaacag gtacacaaaa atcagatacg ggaggttcag gatcagcaat
    28561 ttctttacgt caggcttcac agttccagcc ccctttcctt gattttctcc ttggcccgct
    28621 gcttggtctg ggccgccgcc ttttgcttca cagcggacaa aaccttgcgg atagagggcc
    28681 gctgctcctt ggaaagcgtc ttggcggtaa actcccgaaa cgccagatca aggttatctg
    28741 catccttggc cttgaaaatc acaacgtagt ggggcggctg ggtggtctta tcttttcgta
    28801 aggtaaaatc cacgccgtat ttcttggcgc atggcttgaa cgctccaatg ttggcctcgg
    28861 tgatctcaat gttggagaga tcagccccat gctttttaag ctgctttagg ctctgctggc
    28921 cgtggtgcag cgtgtttttg cccttggccc ggtgttgcag gtactttttc agcgccgctt
    28981 gcagcacttg agccgtgagc ttgcccgttt tcatggacag ggcaatggtc ttttgagtaa
    29041 cttcttcctg caatcgcatc cctccttgtc agaaagtcaa aagcggcgtc taaggcggaa
    29101 ccaccagacg ccgcaggtag atataggtca aatccgcacc cgcaggccgg aaaggtcgtc
    29161 ggcccggatg ccgacaagat accagttttc ggccatttca atgcgggtgg gcctccattt
    29221 gccgccgatc atcacgtcga aacactcccc gcaatgcagg ccgccgtaat agtcggccag
    29281 atcaaagcgg atgtcgtaac ggtctgttcg ctcgtcaaaa atcaatgcgc cctgcttcat
    29341 agggtcgtcc tccttttctc gttacaggct ttcgccctcg ccgcaggaat agtccggcag
    29401 gccggattta ggctttcccc aatcgggctg tgccatgtcg tgcgcgacaa gggccgtgta
    29461 gtagttggaa atggtgctgg gggcgttgaa cagcatagcc cgcaggtatt gtttgatatt
    29521 gcggactttc gttgtgttct cccgcagaca gtcaaggaca aagcggatat gttcgccggt
    29581 cagcttcatg tacttggatt tcaccagctc ggcagggtag tcgtccccgg cgacacggat
    29641 tgtctttcgg gcggtgcaga cggtttccag catcaggtct acgatttcgt caagctgttc
    29701 acggtcaatg ctcctgtcct gaatgagata ggcatactcg atgttctcca aaatgatttc
    29761 ccgataaatc cgtacagcct catcctttcc tgtccttttc cgttccggcg gcgtagccgc
    29821 tgcctcgccc tccatagggg caggggtcgg ggatgggata ggaatggaat gggtactttg
    29881 tccatctgta attatttttt ctttttttga taagtcagtt ctttgtactt ctttatttaa
    29941 ttgcgttgga ttttccgacg ccggattatc cgatgtcgga ttttccaaca ccgggttatc
    30001 cgatgttgga ttttccaata ccgggttttc caataccggc tgttcgtaga tggtatagac
    30061 catatcggcc attttgcctt ttgcgtcacg gccctgctca cgccggatat atccagcttt
    30121 ttcaagctcc cataccgctg tcctgatcgc gtcgatgctt tcccggttga tataggacag
    30181 tccttttagg gtatagtccc aatcctccgg caaggacaac atctgcgaca gcaggccctt
    30241 ggcctttaag gtcaggttct tattccgcag gtggtgattt gacatcaccg tatagccttt
    30301 gttcttttcc acacggaaaa ctgccatagc gttgttcgct cctttcactg tgaatttgac
    30361 cgctgcatag tcggtcagct tgcccggctg atagggacac tctgcaaact ggcagaattg
    30421 atatttccaa tccgggcggt aaaatcggca ggtgccgcaa tcctccggcg cgtccgcccc
    30481 gccgccgtcg tagtgatcga aaccgggctt ttcctgcatc agccgttcaa acgcccggtc
    30541 agggccggaa gtaaatagca tggcgtcgcc tcctttctct atttgggcat aaaaaagcgg
    30601 cgtcctgttc tcccatgacg ggaaagagga acgccgcgtt tacggtgtcg tattcaattt
    30661 atgatgtgcc gtatttgggg tggcgggtat tagcagtatg gttcagcata tatgcggctc
    30721 aatccgaaag tagtaaattg gtagtaaatt gagttctcat atcctgcgaa atgcccgtat
    30781 ttccggggct ttcagcgata acctaaaatt ttctggatac aaattagtca ttttttggat
    30841 ggcagctgtc aattggtctg tcgcttggtc ttgttttgct tcagatgtat tgaatagatc
    30901 ttcatctacc cctgattcaa gatcgatact ttggatcatt tcttcacagc ctgctacata
    30961 tgaaagataa gctttttcaa aatttttatg aatgcccatt gcttttgctg gtggacgcaa
    31021 agtactgact ttcataagca ttgcccgata tttttttgtt ccttcttcaa ataacaggat
    31081 gatctcttca agagtcgatt tgtccagttc acttgttttt ccttcatcaa ttgcgtttct
    31141 gatcacttca tatttcggat gcattccttc tccgattgct tctgtttcct tgacgatttg
    31201 atcgatggac tgcacataat agccaatatt cggtaacatg ttcgttttcc tactttctcc
    31261 attgttgtta ttatttattc tacttgtttt tatcctcaaa tgacaagtac ttgaaaaaat
    31321 ttaatggttt ctatacagct cgccattctt attcgtgctc aaagaaacca tctgctaaac
    31381 tatattgttt ccctgcgaca atgtcatatt ggatcaattg atattcgtcg taaatctctt
    31441 gttgcgagcg attgaattgc gcttctttat accactgtcc gttttgatag tacagttctc
    31501 gttcaaacgc cggaagttcc tgttctaatg ataaaagcag ctgataaaag ccatttgttg
    31561 tctgattcgt ctgttccatt agattcgctg caaaataaaa cggactggtg attgcatcgt
    31621 gagtcgtttg cttttctaat tctcctttac tgtcgaacat aagaaattgt gtttcatgca
    31681 atgtttgttt gtcatttttt gcttggatcg tatctgaata gatccctgga agatgatccc
    31741 cccaaaaaac aactaaagtc cttctagaaa gattcttcaa ttcttccgtg aactgcttca
    31801 gtgccgtgct gctataggaa atatcttgca gataattctc taagtcaagt gtcccacttc
    31861 catctgaagt ttttgcagga tagtctagat tatcatactt tccatcgtag ggcatatgtg
    31921 tctgcatcgt gactaaatga atgaactgag gtgttttttc ttccttgaga agtgtcatta
    31981 cttctttgta agctgactca tcagaaatat atggattatt ctctatcgta tccgtatagg
    32041 tcatcgtacg ctcgctgatg aactggtcaa atcctaatgt ctgataaaca tcctctcttt
    32101 tatacatcga agtattgtat ggatggatcg ctgtcgtctg gtatgattgt gcgtttaacg
    32161 ctgaaacgat agaaggaagc tgatccattt ttggtacaag catcgtgtaa ggggtggtga
    32221 gttgcgcatt aaataacgcc atagaaaaac cagtcaatgc ttcaaattcg atatttgctg
    32281 ttccaccgcc atagttttga gaaagcatat tgccactata tgtttgatca gctacttcat
    32341 aataatctgc caatggctca ccagatactt ctacgccgtt taatcgacta ggatctgaga
    32401 aactttcact catcacgaac acgatgttcg gcgactcttc ctctacagtt ttattttttt
    32461 catcggctag cttctggtat ttttcagtga tttctttgat cttttctttc gaatatcctt
    32521 caggttcatc cattggttct accttcagat tgtacaaaaa cccaccgata aaaccagtgt
    32581 tatagtagtt cattttctgg ctgtaaggta tccatagtgc cgttttatta tatgcttttc
    32641 gcaacaaatt atcgggattg ttgaaattac tgatataccc tagcagtcca attgccacaa
    32701 gcagtgtcgt taatcggatc aattggaatc gccttccttt tttcaggctt cgaaacatgt
    32761 accagcaaaa caatcctatc acggttcctg cggcagctaa gatcactgta aacagcatag
    32821 tgccggtcat atctttcagc aatccgattt cagtgatcat cttcaaatcg tctggataaa
    32881 tcggttcttg ccgataactc attttcatat aatttgcaaa acctaataca ccgatggcta
    32941 cgacatacgt aagggaacct aaagggacag atcctgctag tgcaatcaga aaaataagaa
    33001 taatcagcaa gacgagacag gctaagaaga atttttccgt atgccaagaa aaagcaaatt
    33061 tcaacgcaag gtctacggat agatcatttt gacaccactg caaaaataaa ttactaaaaa
    33121 caacaagaaa aaagatactg atgattgctg ctgttccttt taaaatcttt ttctgtttgg
    33181 tcgaaagtct gcttatatat cttttcaaat gcttgctcct tcatttctat caataaaaga
    33241 atgttgcttc tcttatttta gttgtacgaa attcgaaagt aaagaacgga aagaagaatt
    33301 aatgaaatcc aaatattctc tttctttatg gcctttctgg tttctttaat aagcggacct
    33361 ttcgtactcc agaaattttt tctagctgtt gtttcacttg attgagctgt tcaaaatcag
    33421 tactgtctat gtcaatcaat atgtagacat gctcattctt atggttacgc gatatatctg
    33481 cgatcgctag ctcgttctca ttcagcagag aaaatatctc tgctaatata ttggttttct
    33541 tttgataaaa tatagtgaat cgaaacggcg cttggaaaaa cattcgtgcg gatggataat
    33601 tgaccgcttc tctaaccgta ccgaacaaaa gataatcttt taaggcttca actgccaaac
    33661 gtccgctgtc tgccaaagct tcctgagtcg atccccctag atgaggcaac ataagtatac
    33721 ggtcattttc taagaactct tcttctggaa aatcagtcaa gtatttagcc agatgttgtt
    33781 tttccaatgc ttgcataaca gcatatttat caacaatttc acttcttcct acattgataa
    33841 gtacagcatc ttttttcatt ttttctatat tcgcctgatc gatcaatcct tttgtatctt
    33901 ctgtcaacgg cagcatgact acgatgtaat ccgaggtaga aagaactgtt tctaaatctg
    33961 cttgccgaac ataatccaac tgggcatcgc ggatagaata acccaagaca tccatcccta
    34021 agctatagca acttagcgct acttttgtgc ctatcgctcc aagaccaaga agaccgatgg
    34081 ttttgccttg caattctcgt cccacataag cacttctttt gttttctgcc tgttctaaaa
    34141 tattaggacc tgttagtgtt tgtaccatac gacttgcttc gattatcgga cgggaagata
    34201 agagcaaaca gcacaaaaca agctctttta ctgcattagc atttacacct ggtgtattca
    34261 tgacgatcgt cccgttttca gaagcttttt caacgttgat cgtgttcacc ccaacaccag
    34321 ctcttgaaat tgctagcaaa tctggtgtaa gccattcatc tttcactttc gtactacgaa
    34381 taactattcc ttcggctggc aaatcatcta ttattttgaa atattcccct tgtaactttt
    34441 ctatctcttg ttctggaata gcatcaatca aatgaacgtg atacataaaa ccccctcctt
    34501 actaacaagt atctcgaaat ttctgcaatt agacaactgt ttaccatttg acttcctaga
    34561 agcaaaaaga gcagttagag cagagtaggc tgagtgataa aaataaggct atgacaagtt
    34621 actgccataa gccttatttt cgagagcaaa atattgaggg tgagatatct tgataaatgg
    34681 tgttccgtta gctgacattg ataataagac taaatttcaa aaaagttgaa aagcaaattt
    34741 cgtcaatctc ttcttatttc ttaaaactaa gtggcttttt cacaacctct ttttatctaa
    34801 taaccactgt ttccaactca actaattttg cccacgtttc aatttgatct gttgttagat
    34861 ttagcgagac aacggtatga tgaccgccac ctgcctgaat ccatgaatgg acaccttcat
    34921 ggaaattcgg tttagttttc cataacacac gtgcaacagg taaattaggt gcttcagtcg
    34981 ttggttcaaa ggcttctact tcattgatca gcagtttata atgcgtaccg aaatctgcca
    35041 tcgatacgac taccccttct cctgctttcc catcaaatac aagacgcgcc ggatcttctc
    35101 tatctcccat tgataaagga gaaacaacga ttcttggttt cgtcgcagca agcgtcggat
    35161 ctacttccat catatgggat tccaagattg cttcttggcc actagctagc tcgtaagtat
    35221 aatcttccat gaatcctgta tctttccctc gagccatgat tttcagcaac cgatcaatcg
    35281 ctgcagtttt ccagtcgcct tccccagcaa aaccgtatcc ttctgccatc aaacgttgta
    35341 cagctagtcc aggtagttgt ttcattccat acaggtcttc aaaattagtc gtaaaagcgt
    35401 tatagcctcc ttcttctaag aaacggcgaa taccgatttc ctgctgagct tgtactttta
    35461 catgttcctc ccatgtcttt tcttcataat caccatagtc gaaggtatac aattccttgt
    35521 actcttcaaa taattgatcg acttcttcgt ctgatacgcg atcgattact tgtacaagat
    35581 ctccgatacc aaaataatca acagtccaac caaattgaat ctgtgcttcc actttgtctc
    35641 cttctgtgac acccacgttt ctcatgttgt caccaaaacg agccactttt attccaaaac
    35701 tttcattata ggctactgca acatccatcc aatcagcaat ctctttttgg atctcaggtc
    35761 gtttccagta gccaacgacg attttatttt gtttatttaa tcgagcattg atgaacccat
    35821 attcgcggtc accatgagcg gattgattta aattcatgaa atccatatcg atcgttttcc
    35881 aaggaatgct ttcgttatat tgcgtagcta aatgaagcaa tggtttttgt agaagctttg
    35941 tcccgcggat ccacattttt gctggtgaga aagtatgcat ccaagtgatc acacctgcta
    36001 cttcttctcg ataattgacc tctttcatga tttttgtgat cgtatcagca gtaactgcta
    36061 attcttgaag gcggattgga taaggcaatt ggccattttc attcagttca tcgaccattt
    36121 cttgtgcatg tttctttact tctcgcagtg cttcttcccc atataaatgc tgtgatccta
    36181 caacaaacca aaattctttt tctccaatat tcaacataat tagccactcc ttttatttgt
    36241 tttgtccgta atacgcattt tttccgtgtt ttcgtaaata atgtttatct aaaatccgtt
    36301 gaggcagctc ttctgaaaat gaattgagct gtctggtaaa taaattcatc ttgcatactt
    36361 catctagtac gactgcgttc attaccgcac tttgcgcatc tttcccccaa gtaaatggac
    36421 cgtgtccgtg taaaagtacc cctggaattg ctaagggatc aattttgcgt tctttgaatg
    36481 tttctatgat aacttttcct gtttcatatt cgtacccgct gtcgatttcc tgttgtgtca
    36541 aaaatcgagc acaaggtacc gatccataaa aagtatctgc atgcgtcgtc cccatcgcag
    36601 gaacatccaa tcctgcttgt gcccagatcg tcgcccatgt cgagtgagta tggacgattc
    36661 ctccgatttg aggaaatgaa cgatataaaa cagcatgagt aggcgtatcc gaagagggat
    36721 tgagtttacc ttcaatgata tgattgtcca agtccacaac gaccatgtcg tctgctgtca
    36781 tctcttcata actgactccg ctaggtttga taacgaaata tcgtgtttca ggatcaaaag
    36841 cgctcacatt tccccatgta tatttgacga gtccgtgttt aggcaagtca agatttgctt
    36901 ggtatacttc ttctttcagt tgttccagca ttttctatca ctcctttttc ttgcaattga
    36961 tgaatcgctg ttttttcaat gtcgatcccc tcacggtaac gtctcataaa tatctgatag
    37021 cctgctattt cttctgctga aggtgtgatg gtgattcctt ggtcttgtcc aaacacgtct
    37081 tctgccaaga agttttctaa agacttccca tgtcgatcca tcatataggc tgctaataac
    37141 gcgattcccc acgctccacc ttctccggct gtgtccatca ctgtaactgg tgcctccata
    37201 gcagatgcta gaatccgctg tccaacttct ggtgttttaa aaatcccccc atgccccact
    37261 aaacgatcaa tttggacatt ctcagatttc aatatatcca ttccgattct cattgcacca
    37321 aaagcactgg ctaaatggat ccgcatgaaa ttcgctaaat caaaacggct acctggtgta
    37381 cgtacaaata atggccttcc ttcatttact cctgtaatgt tttcaccgga aaaataacca
    37441 taagaaagta atcccccgca atccgtatcg ccttctagcg ctttgttgaa taataccgtg
    37501 aataatttat ctctgcttat ctccataccc aaagaattgg taaattcttc aaaaatactg
    37561 acccaagcat tgatatccga agagcagtta ttcgtatgaa ccatgcctac tagttctcct
    37621 gaaggtgtag tgaccatgtc gatttccgga tggacatttt ctagttcttt ttctaatacg
    37681 atcatagcga aggcggaagt accagccgaa atgttccctg tccctttggc tacactgttc
    37741 gtagcgacca taccggttcc tgcatcccct tctggcggac aaaccgggat tcctggtctc
    37801 aaatttcccg tagggtcgat cagataagcc cctgattcgc ttaacttgcc agcttcttct
    37861 cctgctacta gaactttagg caaaatgtga tccaagtcaa tcgctacgtg cgctttttcg
    37921 attaactgac caaaaatatt tttcatttct tgatggtagg ttttcgttga aggatcgata
    37981 ggaaacatgc ctgatgcatc tcctacgcct agtactttct caccagtaag ctgccaatgg
    38041 acataacctg caagcgttgt caaaaaatta atttctttca catgttcttc tttattcaaa
    38101 atagattgat acaaatgagc gatactccat ctctgcggaa tattgtattg aaatttttcc
    38161 gttaatattc gttctgcttc ttcagtgatt gtatttcgcc aagtacgaaa tggtactagt
    38221 aactgttcct tgctatcaaa tgctagataa ccgtgcatca ttgcactgaa cccaatcgac
    38281 ccgattgtcg taagattctc gccatagatt tcgaatactt ctgctgccat ttttcggtaa
    38341 ctgacgcgca gtcctttcca aatatcttct aatgaatagg tccagatacc attttctagt
    38401 ttgttttccc actcataact accagcggca ataggagtaa aagatgaatc aatcaataca
    38461 gctttgatcc tagttgatcc aaactcaatc cctaaagatg tacgaccatc tatgacatct
    38521 aacatacttt gcgcatttac ttccttcata atgatttaac tccctccttc tcgtcaaacc
    38581 tgatcaaacc gtctttttag tagcgcttac aatgattatt gtatactttt gtacgtacat
    38641 gtcaagcagt tatttacaag aatacaataa aaaacacttg ttttgtacgt acataagtta
    38701 taaaatgaaa ttgcttacaa aatctgatca accgccttct cgaaattcta gaaggagaga
    38761 atacttatga aaaaagaaaa aaaagtttcc tcatcgttta tttatttttt tggcgcattt
    38821 ggcggcattc tatttggata tgatattggt gttatgaccg gcgccttacc ttttttacag
    38881 catgattggg gtttggcagg taaagcttct ttgataggat ggatcacgtc ttcggtcatg
    38941 ttaggtgcga tccttggcgg ctctttatct ggtcttcttt ctgataagct tggacgacga
    39001 aaaatgattc ttctttctgc acttattttt atggctggtt ctgtcctttc tgcatctgcc
    39061 cctcacaatg gttcttattt tctgattgca gcaaggattc ttctaggttt agctgttggc
    39121 gctgcatctg ccctagttcc tgcttatatg tctgaaatgg ctcctgctag actaagggga
    39181 agattgtcag ggatcaatca agtgatgatt gcttctggca tgctcctttc ctatgttgca
    39241 gattatttgc taaaagggtt gcctgaaacg atggcttggc gcgtgatgtt agggctcgct
    39301 gctgtccccg cgctgatttt atttttcggt gttttagctc taccagagtc accgcgtttt
    39361 cttatgcaat ctggccgctt ggaagaggca aaaagagtat tgaactatat tcggacacca
    39421 aaagaagctg aacaggaatt cgaacaaatc cagctgaatg tcaaacaaga aaagacaacc
    39481 ggaacttctt ggcatacttt gtttttagaa aaatatcgtt ccttagtcat tgccggtatt
    39541 ggtgtagcag tattccagca atttcaagga gctaatgcta ttttttacta tattccgctg
    39601 atcgtagaaa aagcgactgg gcatgcagcg agcgatgcat tgatgtggcc gatcatccaa
    39661 ggaatcattt tagttgctgg ttctttgctc tttttggtta ttgcagacaa gttcaatcgg
    39721 cgaactttat tgaaaatagg cggtagcgtg atgggacttt ctttcatcct accagctgtt
    39781 ttaggaactg tactggatgc tcatacaaat tcgttgttga ttctcttgtt tttatgtatt
    39841 tatgtcgcat tttattcttg cacatgggct ccactgacat gggtaatcgt aggcgaaata
    39901 ttcccactag ctgtccgcgg gcgagcatct ggcctagcct cttcttttaa ttggattggt
    39961 tctttcctag ttggcttgct ttttcctgtg atgactgctt ctatgtctca agaaatcgtt
    40021 ttcggcattt ttgggatcat ctgcttttta ggggttttat ttattcaaga gatcgtacca
    40081 gaaactcgtg ggaaatcttt agaggaaatc gaacaaagtg catctaaaaa aacttatcct
    40141 aaacgtattt ctatccatca ttcttaaaga ggttgtgaca gaagtggtca gcttcaagaa
    40201 ataagaagga accgcttagt ttccagtcac aaggaacaat ttcaaaaaac agcttctcat
    40261 gtttgatgaa tattgtgact tgtgaccagt tggtaggaga acaccgttta gtggagaggt
    40321 ggtgaaagaa acgttcagcc ttgagcgatg acaaaagctc tcacaaacat tgcgacgagt
    40381 aaccgtagga gcaataagag gcggtaaaaa cccgtctctt atttttcgtt ttctttcact
    40441 gtttcccgtt caactagtac aggttcatag agaatatttg gctgtgcctg tcctttttca
    40501 atcgttgtga cgatccaccg tgcggcatct tgtcccaact tttcttttgg atgcgtcaat
    40561 gttgtcaatt ttttattccc taaatggctt aaagaagaat cgtctgttcc tacgatcgat
    40621 aggtcatctg gaatatgata gccattttct gtcaacttat ctagcattaa actagctatt
    40681 tgatcgttat agcaaatgat gccatctaaa gcttgttctt ctttcaaccg ttgtactgtt
    40741 ttttcagcga ttgtttctcg tgtttccgtg gtgaaagtaa tgatatcttc cgtcaaaaaa
    40801 cgcacattat actgttcaca cgcgctgata aaacctttca tcctgtattt tccttgaaga
    40861 tcgtcgattt ttgtgatgaa caacagacgc tgatgtcctt tttttatcaa atattctgct
    40921 gccataaaac cgactttcac atcatctaaa caaatataag aggcatttaa ctcttcataa
    40981 gcagcattga tcatcaccat cggaatgcct tgttctctca aagcaacata aagtgctaag
    41041 tttgggttat actgattact tttcgtaggc tcaacgatca aaccatctac cccataagca
    41101 atcattttct tcaaacactc tttctccaat tcgtgatcgt tattcgtact ggctaaaagc
    41161 aatgaatacc cagattctcg taattcattt tcgattcctc ggataatcga cggaaaaata
    41221 taatcagaga gatatgtggt gatgacaccg atcgtttttg ttctgttcaa tggtgttttt
    41281 tctttcttat agctgtcatc tacatatgtg cccgaccctt tttctttacg cagatagccc
    41341 tcatttacca acacagcgat tgcttgccga atcgtatgtc tgctgacgtc atatatttct
    41401 tgcagcttga attctgaggg aatggttgta tttacttcgt attcctcacg aaggatcttt
    41461 tgttttatct cttctgcaat atcttgatat tttgccattt gccttgcccc tttttatttg
    41521 tacgtacata tatcataacg agtctgcaag gtttattcaa gcaaaaatca aggtttcttg
    41581 tgctcataag gcatacggaa caggttcacc aaattctgga aatccttgct cattccacgt
    41641 aaagcattgc gcgttcgcgt gccgattagg attgtctaac ggatcccctt tttggttctt
    41701 ctctggtcga gcatgataga tcaaaatatc aaagcacccg tcttctgaaa ccgtaaacga
    41761 gttgtgacca ggaccaaatt gcttattttt ttcagaagaa acgaatactg gctccgataa
    41821 tttatgccat gattctttta ataaaagatt cttgtgctca tcagcccaca gcaggcccat
    41881 ggcatagttt tcatctgttg cactaccaga atacgtaatg aatattttcc cattgcgagt
    41941 aaggactgct ggaccttcat ttactgaaaa accccgtttt tcccattcat actcaggtat
    42001 agaaaggagg atctgcttcc cctttaacgt ccaaggatta tccatttcgg atagataaag
    42061 attagaattc ccagtaattt caggatcttg ttgggcccac acataatata gctttccttg
    42121 agaagagaaa gttgttccgt ctaaactgaa agtttccctt ttcgttttta tttgtccctt
    42181 ttctatccaa tctgtattca ttggatctat atgctgattt tcaagtacga acatgcggtg
    42241 atgatgagat tcatcacgta tagttttatg attgcttgca gcaaagtaaa tataccattt
    42301 tccattgata taatggactt caggtgccca gatcaattca ctcatcggtc cttcttcatg
    42361 agcctgccat acaatcaggc ttgcagcatg ttctaattca ttcagtgact ttgcccttct
    42421 taattcaatc acttggtagc ctggaaccga tcctgtaaaa taataataac catctgtatg
    42481 tttatatacc caaggatctg cccgttgccg aacgatagga ttattataaa gtgtcttcat
    42541 cataacaaat ttcctcacat tttctttatt ctaattacat tccaagagta tttttctatc
    42601 cctacattta attcgtcatg tttttctatt gaaaaatagt ttatttcagg ttttattttt
    42661 tctggttctt cacgtgtatt tttgtccaac agatcgctac tggttaatgt gtagtgctct
    42721 ccttgatcta gcaaattgaa atcatgttca atcgttatct tttgttgttc atttgtgcga
    42781 ttgatcaaga aaatagtcag ctgattgccg ttatctacga tcacactgtc cacataagga
    42841 acatttttta tcttttcaca atcataaaca gggcaaatga tttgttgttt caatacttga
    42901 cctttagcat atttcgataa gtgttgcatc acataataag ttggattcct ccatgcttgt
    42961 cctttagcat ctgtcagtat taaaggtatt gtgtttacta acaatgattg acaactaatc
    43021 tttacgcgat ctgcgtgtcg taaaatagcc agccctaatg aaccaaataa taatgtatct
    43081 tccatagtaa agtaacacca atcgatggga ctaccgactt caaaatccct atgtcttttt
    43141 tccggttggg catgtacatt ccattcatca aacgctagat acattgtttt ctcacttctc
    43201 aaatatcctt ttacataatc acaagtagca acgatttctt caatttgacg atcgaatcga
    43261 taagcttttg caaggtatgt cgctgtatca tcacgctcat ttttaggagg tttagtcaag
    43321 tcttcttcat catacttatc aatatagtta tgcaaagcta aataatctac attctcataa
    43381 gcttcttcta atgcgatacg atcccattca gggtacgatg gtaaacgtgg cgtagagctt
    43441 ccaactaaga ttgtttcaat tgaatcatcc actaacttca tgacttttga ggcttcattt
    43501 gctaacctac catattcata agcactctta gcccccactt gccatggacc gtctagctca
    43561 ttccctaaac accataattt aacgccaaaa ggcttttttt gcccattttt tattcttaaa
    43621 tcactccaga aggttccttt tggaaaatta caatattcta ctaaattttt tgcttcatca
    43681 attccttttg ttcctaaatt caccgtgaat atcggtttcg cttgtacatg actgatccat
    43741 ttaaaaaatt cgtggagtcc aaaagaattt ggttctatac ctcgccatgc taaatcaatt
    43801 ttttttggtc gttgttcttt cctacctaca gtatccaccc aatcataacc agatgtaaag
    43861 tttcctccag gatagcgaat gacacctaat tctaattcct ttacataaga gaggacatct
    43921 tgtctaaacc cgtcaccatc agctgtttca tggcccggtt cataaatccc tgtatagacg
    43981 acacttccca tatgctcaac aaatgagcca aacagccgag aactgatctc tcctaccgta
    44041 aaatcctctc tgatttttac tttcacttct tcgtccaaca gctttcccta cctttcattt
    44101 cctatagtca agataataga tacaagtttc catacgccac cagcaaagat aaaaataaaa
    44161 ggagggaaaa gaaatatgag cagtacaaat cctaataaca atacgcaaca aagaatattt
    44221 ctcaaaaaat caaaaaatac tttccatgca ctttgttcaa aaatttgtaa aaatgtgata
    44281 tctttgtttt cagaaatcac atatatccag gataaaagaa acatggaata aataagtaaa
    44341 actacatatc cactaattga aagtacgatt gtctgttctt ctaataattg attaacaaga
    44401 aaataaataa tgatcgttaa cagactaagg aacaagttct taccaaaatg ttgctttatt
    44461 ccttgaaaga aaaaataaat gatatttcct gatccctcac ctttccattg cgccattaca
    44521 taaaaaaaca gcacatgtag caggcacgat agtaataaca ggcaaacaca cgattaccca
    44581 gagaatacct aataagatgt aatcagaaac cacaatcaac tgtccataaa gtttagtctc
    44641 aactattttc atcttcctca ctctttcatt ccagacatag ctgttccttg aacaaaatat
    44701 ttctgtgcaa aaatataaac cactagtaat ggcagcattg aaataaccgt tccagccatt
    44761 acaggtccat aaaaagaaat gttctgccct gtaaataaag ctaaccctgc tggtaaagtt
    44821 ctcatttttg aactacttgt caatatcaat ggataaagca agtcattcca actattcatc
    44881 agcgtgaaaa tccctaatga taaaagagta ggtttgctca atggcaacat gattttcaaa
    44941 aaaatattaa actcacttaa tccatcaatg cgtgctgcct cttccaaaga atctggtaaa
    45001 gtaataaaaa aggaacgcat catgaagata ccaaatgcag ttgtcatacg aggaatgatc
    45061 aaacctgcat aagtatcaag catgccaagc aaattgactt caataaatag aggaatcatg
    45121 aagacttgga atgggatcat cattgtcagc aaaacgaaat agaacaaaac tgattttcct
    45181 ttgaaacgca tacgagcaaa tgcatacccc gcaagagaat caaagaatac agaagtgatc
    45241 actgtccctc cagcaaaaat cactgtattt ttgatgtaat ctaataaagg gatcgttgtc
    45301 caaaccttaa tatagttatc tagggtatag ctatctgcaa atattctagg cggaaatgag
    45361 ataatgtctt tttcgtgttt aaaagaagaa ataatcagcc acaaaaaagg aaacgcaata
    45421 accaacaata taactagcat actaatcgtt cgaatgattt ttttaccact aactgctttt
    45481 cgactattca cagtaactgt aatcgagctt tctggtgcca tacaggtttc cctcctattt
    45541 catttgtttt tctttccgtg acatgtacac attagtggag atagctatag ttgcaacaat
    45601 gataaacaaa accgaagaca gtgctgatgc atagcccaat tcataaggtg ctgtaaatcc
    45661 tcgactgtaa atatattgaa cagctgtttc tgtcttaaat tgtgggccac cagcggttgc
    45721 aacatatact tggtcaaaca cttgcatcga accaatcaga ttcgttaaaa tacaaaaacc
    45781 taaggaggga acgatctgag gtagcgtaat gttaaaaaac tgctgtcgat ttgttgcacc
    45841 atccatttga gcagattcat acaaagaggg agagattccc tgaatagcag tcaagagaat
    45901 cgtcatagta acaccaaaat tcttccaaac agtcatgatg gctaccgtcg gcatagcaag
    45961 ggttggatcg cgaaaaaatt gagggatcgg caagccgact tgtgaaaaca agtaaggaat
    46021 cgcccctaca ttcggatcaa gcaacataga aaaaataatc gcaattgacg tcaatgaaca
    46081 aataactgga atgtaaaatg tcgaacgaca aaaacgattg aatctggtat ttttagataa
    46141 tgctactgct gctaataaac caacgataat ttgtgttggc gtttcgagta cggtgaaata
    46201 taaagaatga atcaacgaat taactgctcg ttcatcacta aatatacgtg tgaaattttc
    46261 aaaacttaca aaatttcttg atgtaaagaa aatattcaaa tctgtaaaac taatagcaaa
    46321 tgttcctaaa agcggtatga cagtaaataa taataaaact aaaaaagatg gagttaaaaa
    46381 caaatacgca gcacgatcag gacgattcca atatttggtg aatccgttca tatagtccac
    46441 ctcatctttc attttgataa aatatacaat cttggtttaa acgaatctga ataagatatc
    46501 cgaacaatcg ctgtgatttt tgcaataaca cctatctgca aatactaggt cgatcattca
    46561 gatatctgta tcttgccaac agtctatcct gtataaagtt ctgtactatt tttgcagtaa
    46621 ttgattgatg gcatcatctg catcgttcat gagtgtctca ggatcttctc ctgctaataa
    46681 tttttcaatc agtggattga tgatatcgtt attgatcgca gagatttggg taaaacctgg
    46741 taaatatggc tctgcatagt ccatttgttt cgataattca gatacaatag gatcattttt
    46801 tacttcttca tcttttgcta ctgaatccaa gtaggcagga aaaccatttt cgatactcca
    46861 ttttttacca atttcagttg tattccaata tttcaaaaac tcatagacag cttctttttt
    46921 attattatct gtacttgccg gaatggcata tcctacgcca tctaaaatag ctgttttttt
    46981 gtctgaatca ctcccttgtg gtaaggtagt cacattataa tcaatctcgt ttgctttcaa
    47041 tccgttattt aaccatggcc cattgatttc aatggctagt tgaccagcat tcattaaatt
    47101 gtccatttcg gcgccagaaa tcgattctgg accagtcttg tctacatgga tcattttttg
    47161 gatcgctttt aacgttttaa ggttctcagg agacgcaaat tcagacttag tataatcatc
    47221 gttcactaat ttaccgccat ttgctaacat ccagttatat aacggtgcag ttccatcctt
    47281 attgaagaca aaacctgata catttttact actatcagtt aattttggtg ccatttctgt
    47341 caattcttcc caagtagtag gtggttgttc agtatctaat ccagcttgtt taaacaaatc
    47401 attattccaa tacatataca tgccttgtac ctgcatgggg acaaaatact gtttaccttc
    47461 tacttcacct aattcaatag ccgtttcttt aaaatcagat ttatctactc catcatattc
    47521 ccagaaatcg tctaatggtt gtaccgctcc gttttctaca tactgtgcaa aatctggata
    47581 atttaatgca ataaagtcag gtgctttttt agaagaaatc gctgtaggaa gtttttcatt
    47641 caaattggcc caagtcatga tatccatttc aattttgatg tttttatcat ttgttttatt
    47701 aaattcatta acgatttctt gcaatatttc accatcagat gcagtaaacc cattccaaaa
    47761 agtcaaagtc acttctttat cagaatcaga ttctgctgaa cttccgccac cgcaagctcc
    47821 taaaatacct gttgcagcta ccaacaaaga gccaattaac cattttttac ctttcatttt
    47881 ttgttcctcc ttcatctgat aaacgacatc tgaccacatt ccaagatagc ggtttcaata
    47941 aacaattgat tttcccatct tcagctttta catttgttga atgacttggt tttacttgtt
    48001 cacttttagg aagattagtt gcttttgtat caaatccact catttcagaa aaatcaatca
    48061 ctccctctaa tgataattca gacaagtgaa cagttagatt catttcttct tctccacggt
    48121 taactgcaaa tatgacaagt tctttgtcat ttattacggc tatactttct aaatacggca
    48181 cttcttcaaa atcttccgtc gcatagtttg ctgaacgaat ttgtgggctt aacacctctc
    48241 cttgtccata cacagcagct tgcataaatg gataatagat cgtctgtctc caagcttctc
    48301 cgtttgtttc tgtcctgatt ggtgcaataa catttaccaa ttgagcaaga caagcaatct
    48361 ttactctatc tgcatgtttc aataaagtga ttaatagaca gcctaatagt aatgcatctt
    48421 caaaattata gttatcttct agtaaaggag gagcaatctg ccaaggcgct gcttgctcat
    48481 cttgttccgc tgaatgatac caaatattcc attcatcaaa ggacaggttg atctgcttct
    48541 tactatgttt cttcgccttg actgtatcgc acatcgctgt cacttcagaa atgaaccgat
    48601 ccatgtctaa ggaacgtgca agataatgag aaagatcatt tttttggttg ccataatatt
    48661 gatgcagaga caaataatct atttgatcgt acgcttgatc aagaactgtt aactcccaat
    48721 caccaaatgt aggcatttgc cgattcgaac ttccgcataa aaccacctca attgaatcat
    48781 ctacgagttt catcgcctta gccgtttcct ctgctaaccg tccatattct tccgctgttt
    48841 tatgtccaat ctgccaagga ccgtccattt cattccctaa acaccatgtc ttaattccaa
    48901 aagggctctc ttgaccattc gaacgcctta aatcactcca ataagttcct ttaggaaaat
    48961 tacaatattc gactaaatta cgagctgcat ctactccacg agtacccaga ttgacagcca
    49021 tattgatttc ggcccccaca tgctgacacc agttataaaa ttcatgaatc ccaacttcat
    49081 tcgtttcaat tgtccgccaa gctaaatcca accttctagg tctatttgct atgggcccaa
    49141 tactgtcttc ccaacgaaat cctgacacaa aatttccacc aggatatcta atcatgggaa
    49201 tgttcaattc ttttaccaag tgaatgacgt cttggcgaaa tccactttta ttagctgatg
    49261 gatgatctgg ctgataaatc ccttcatata ctgctcgtcc catatgttca ataaatgaac
    49321 tgtacaaccg cggatcaact ttgcctacac gcttgacact actaatcaac attgtggctt
    49381 ccataactga cctcctttaa tttatacatg aataatacac ctcgttgaaa gcgttgtcaa
    49441 taatataaat gttaaactta cttatttttt atcgatttta attaaccaaa atattaataa
    49501 tgattaaaac aaataattta atataacttt tattaacaaa tatgttaata tataagaaaa
    49561 accttttaag aggtgatata tatgcaacta caaataaacg aagaatcctt accggtatat
    49621 gaagcattag ctagtaaaac aaggatcaag atcatccagc tactttccaa aaaaaagatg
    49681 aatgtcaaag atttggcaaa agaacttgga gtgagcagtg ctatcacgac gatgcacgtg
    49741 aaaaagctag aggaagcaaa catcatcaaa acagaaaaag taggacaaca aaaaatttcg
    49801 agccttcgtg tcgataaaat cgatatcagt tttccagaaa aaatattcaa tgcttttgat
    49861 acgaaagaaa catcgatacc tattggtcac tatacaaatt atgcaattga accaacatgc
    49921 ggtttagcta cgatccatga ttttatcggg aaagtggatg aaccacgcta ttttatggat
    49981 cctcgaagga tggatgcccg cattctctgg tttaccagcg gatttgtcga gtatcaggca
    50041 cctaattttt taaatacaga ggatacattg gagatgttgg aagtttctgt ggaaatttct
    50101 tctgaatttc ctttttcaaa tgacaattgg ccttcagata tcactttcag cctaaatggt
    50161 gtggagctag gaacatggac gagccctgga gattttgctg atatccgcgg taaatatacg
    50221 cctgattggt atccagataa tcttaatcaa tacggcttgc tgaagacgat ccgaattacc
    50281 aaacacttga cgaatatgaa tggagaaccc ttgtcaaaca tcacgatcaa cgacatccct
    50341 aaagagcaag acacttggca tttgcgaatc gaagtgaaag acgatgccaa acatgtgggg
    50401 ggctgtactt tatttggtaa aggattcggt aattacgatc aggatatcaa attaaaagtt
    50461 tactacagct gatatttttc ttttctattt tataaaacaa aaacagccaa tccctatgaa
    50521 gggacggctg tttttgcttt attgttattt ccagaaatca tccaaaacgg aaattggcaa
    50581 atgtcgttta tgttgtgtct tgttccacca tgcttcgatt ttttcttgtg cttgagcggg
    50641 aacttctttt ccttctagat aatcatcaat ttcattatat gtgacaccta gtgcgacttc
    50701 atctgcaatc attggtttcc catcttcaag atctgcagtc ggaatttttg tgtataattt
    50761 ttccggtgca ttcaatgctt gaagcaattg tttcccttgt cgtttgtcca aacggaataa
    50821 tggcaaaatg tcggctccac catcaccaaa tttcgtgaag aatccagtaa tgttttctgc
    50881 agcatgatct gtccctaata cggctcctgc tctttctcca gctacggcat attgcgtaat
    50941 catacgttga cgtgctttga tatttccttt gttaaaatcg ctgattccca cacctgcttc
    51001 gcttaatact tgtacttgtg catcaacagc tggtttgata tttactcgca gactaacatc
    51061 gggctggata aagtcaagag cagcttttgc atcttcttca tctgcttgtt caccataagg
    51121 aagacgaaca gcgataaatt gatagttttc atcttttgtt tcttcacgca tttcttccat
    51181 cgttagttgc gccaaacggc ctgctaaagt agaatcttgg ccgccgctga tacctagtac
    51241 aaaagtttta agaaacggat attttttcaa atatgctttc ataaagtcaa tacttttacg
    51301 tatttcttct tttggatcaa ttgttggttt gacacctaat tcattgataa tttctgtctg
    51361 caggctcatt tattctcctc ctatgcttct gtatgaagtt ctgctacgct ttttttcatt
    51421 cgttccatga tagccatttt atggttccag cattcagtag acagatcgac tgggtatttt
    51481 tgcggattca agtctcgttt atactcttcc catagtgaat ctagattttc ttttgtatat
    51541 tctttgattt cgtttagtgc aggtaattcg taaactcttt ttccttcgat aaagatatct
    51601 tgtaaaactg ggcgagctgt aaagtctcga acagttttat tgataaacgt atgcactgga
    51661 tggaacatga agatagcttc ttcttctcga gggtcttcat cccataatgt cacgtagtct
    51721 ccttcagatt tcccatcaaa atttcgagtg atgcgccaca cttgtttttt ccctggagta
    51781 gttacttttt ctgcattgct tgataacttg atcgtatcca tcatttttcc ttcatcatct
    51841 tcgatcgata ctagcttgaa tactgcacca agggctggct gatcataggc tgtgatcaat
    51901 tttgtcccaa caccccatac atcaatttta gctttttgca tctttaaatt caaaatcgtt
    51961 gcttcatcca agtcattcga agcatagatt tttgcttccg taaatccggc tgcatctaat
    52021 tgttcccgaa cacgcttaga tatataggcc atatctccac tgtcgatgcg tacgccttgg
    52081 aagttgattt tgtcacctaa ttctttcgcc acgcgaatcg cacttggcac acctgatttc
    52141 aacgtatcat aagtgtcgac taagaacacg cagtctttat gggttttagc gtaggccata
    52201 aatgcttcat aatcatttcc ataagattgg actaacgaat gagcatgggt cccgctagct
    52261 ggtatcccaa atatcttccc agcacgtaca ttgcttgttg catctgctcc gccgatatat
    52321 gccgctctag ttccccagac tgctgcatcc agttcttgtg cccgtctagt tccaaattcc
    52381 aatagtggat cttctccgat gacagatttg atacgagctg cttttgtcgc gatcaacgtt
    52441 tggaaattga ccatattcaa cagtgctgtt tctactaatt ggcagtgcgc taaaggccct
    52501 tccacttgga ttaatggttc atttgcaaaa actagttctc cttcacgagc agaacgaact
    52561 gttgctttaa attcaaaatt ttgtaaatac tccaaaaaac cttcaggata gacttctaat
    52621 ccacgcaagt aagcaatatc ggaatcattg aacgtcagat tctctaaata attgactaac
    52681 cgttccaatc ctgcaaaaac cgcgtatccg tggttaaaag gcatttctcg aaagtaacat
    52741 tcaaaaacag catgtaaatc agctcgacct aattcccagt atgtctgcat catattgatt
    52801 tgatatagat ccgtatgcag cgtcaaactg tcgtctgggt aagtattatt catcttgtat
    52861 tactcctctt ggcaagtttt catttcctac ccattataac aaaaaaaatt aataggaaaa
    52921 gaaatcttcc attttttctg aaaaagcaca tgttttacgg atatttcttg ctaaaaatga
    52981 actccatctg ctaaaactat cctttcttat tggtatttaa cctaaacgag aaagaatact
    53041 tattttattc aatgtatccg agacacgaag aaattagcgt tttctatttt tcttacttga
    53101 taaaataagt agattttcct actacaatcg tagccgttaa gataccgatg attgaacaaa
    53161 tataaccaaa tgtctctaca acataatcaa tggcaaaagt ttttgaagca ataatacgtc
    53221 tttccttttt tgcttcttat ccccaaagaa acggatataa cttattatgt attgaatttt
    53281 tttggaaagg cgaattatga caagatatac cttgcgttga aaaaactcgc ggaaaaaata
    53341 tcacacgttt ttaaaaagat acaaagtaag aaagcagctg tcaatagaat ggaaacaaaa
    53401 atggcgagac atcaatcagt ctcgccttgt tttttattgt atacattaga tatggagcag
    53461 gttaccataa agatgattat tagtcgttat taaatagaat ccttcgtatt tttttgttct
    53521 atcactacaa tatctttatt tggacgtttg aattgtattc cggcacgttc tagctcctgt
    53581 ttcactccta catggacttt gacatcttct cgtgtcattt ttaaaacgtg atgaatcgca
    53641 tagtcgattt cttgccttgt gatttttttc ttcgtattga tcatcacgac ttgcttttta
    53701 tcatatgtgt ctaccaatag cagttgtgtt cgatctaacg aaaataattt gtaataatta
    53761 atagccgtat tcccaaaaaa gaattccact actttaggat aaaatgtctt aatatttaaa
    53821 ttactattca caggtgtttc gattagcttc atctcattcc tcttttctat atagtcgatt
    53881 tagatccaat cttaagttat gttaccatct ttcctagcat taaggaatcg gttacaattg
    53941 aacctttaaa gacaaaagga tttacctttt atcacttaat agtataacat aatttcgtga
    54001 gaaaaaaata caattttttc ttgaccatct cgttacgtaa aggattatgc ttacatttgt
    54061 caggaggaaa aataatggag tacacaataa agaaaatgtc agagatatca ggagtcagtc
    54121 cgagaacctt gcgcttttat gatgagattg gactgctaaa accagctagg atcaattctt
    54181 caggttatcg gatttatggc aaaaaagaag tcgatcgtct gcaacacatc ttattttatc
    54241 gaacaatggc attcaagttg gatgatatcc aagaggtctt agacaatcca tcttttgacc
    54301 accagaaagc tttaatcaag catcagcaaa tgttgctgga aaaacgggca caaatcgata
    54361 ccctcttgac aactgtccaa cagacacttg atatgtacga aggaggaaga aaaatgagtg
    54421 acaaagaaaa atttgaaggg tttaaacaac aaaagttgaa agaaaatgaa gaatcctatg
    54481 gacaagagat tcgacaaaaa tacggaaaaa aaaaggttac agcatccaat gaaaaatgga
    54541 tgaatatgga taaagaaacg tatgaagaaa tgcaaactgt tgaaaagcag atgttatttg
    54601 atctcactct ttacttaaaa gaaccagaag atgaaagctt agcagaccgt atcttccaag
    54661 ctcataagaa gtggttctct tacagctggc ctgaatatca gccaaaagcg cataaaggac
    54721 taggaatgat gtacgaagcc gatgaacggt tcactgcata ttatgacgag cgaagtggtc
    54781 atggtgcagc aaaagcttta aatgaaatta tccaaaaaaa ggcgtaatct tttacatgat
    54841 ccaacaaaaa agtacacgta aaatgaccta ataacaaaac agcagacacc caagttagat
    54901 ttttatgcta acttttggtg tctgctccat tctttcacaa gttttttcat cctactttaa
    54961 atatattcat cgttgaataa acgtataagg tattttcact ttatcctttt tttctgtaag
    55021 aaacaattga aatgccattt ctccgcaagc ttccagatgg tggtcgatgg ttgggaaacc
    55081 aagaagctcg ctgatcagca aattatcgcg tccaatcacc actggtgtct tatcttgcag
    55141 atagctttgc aagatgcctg ctgcaaccat atccgaattt gtaaagacac catcaactcc
    55201 aagctcttta aaaaagaagc ctgcttgttt tcctttctct gcatctatac aatcccaaaa
    55261 aacaagtgat tcatcaaaag atggaaaaag ttgatgacat agctgcaaag tgatttttga
    55321 gttataactt agcctgccac ttcgccccaa cgtgatgccc aattgcttta taccttgctg
    55381 cttcaaataa gtaagacctt ctgtaattga ttgttctcga tcaataaaga cacagcttgc
    55441 ctgttttccc ttgatttctt cacaaaaaac tagaggtcca tatttttgat atgccaataa
    55501 atcatctagt gtattggcac gagacgtaat gatcaatcca tcgaaagctt tagctgcaaa
    55561 ttcttcaaga taccttcgct ctttttcttt atgatagccc gtcggtaaaa gtgtcacttt
    55621 gtaatcataa tcaaacgctg cttcaatgat cccactgatc aactgatcaa aatacggatg
    55681 attggtataa ggcagaatca ctccaatgct tttcgttttt ccataactta actgtctggc
    55741 atttgcatta gggatataat cgacttcttt catgaccgca agtatttctt tccttttttc
    55801 ctcatctaca tatggatgtc cattgattac acgtgaaata gtagaaactg aataacctgt
    55861 gagctttgcg atatctcgaa tgtttgccac tgctgcttcg ccacctatac aaaaagattt
    55921 tcttgtaaat agtctaccac agctggaccg cattcaaaaa actgatacat ttttccttca
    55981 tgcgaaaaac tgatccgctg cccgccccaa tatatatctt ttgtcaaatt ttcgatttca
    56041 ttcattggta tttcttttac tatattccta ttcaaccctt gaaaactgta caacgttaat
    56101 acggatccct tgaactcgac aaacgcataa aaataattgt tcgttgtgcc atctgttatc
    56161 tctacataag tattcattgc aagccctcct tttgatactt tgagtatagt gtatgaaacg
    56221 cgtctcatag caaggagttt gttttgccaa agaaaagttt tattcctctt tcattattac
    56281 caaagtctct tattttaaat tgaatacatt ataatgatac tgtaaatata tctttattat
    56341 tagtgaat
//
LOCUS       DAMEEU010000008        54587 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.008, whole genome shotgun sequence.
ACCESSION   DAMEEU010000008 DAMEEU010000000
VERSION     DAMEEU010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 54587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 54587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..54587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.008"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            150..1208
                     /locus_tag="PB779_000517"
     CDS             150..1208
                     /locus_tag="PB779_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HDE0738062.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            1212..2246
                     /locus_tag="PB779_000518"
     CDS             1212..2246
                     /locus_tag="PB779_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HDE0738063.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(2348..3064)
                     /locus_tag="PB779_000519"
     CDS             complement(2348..3064)
                     /locus_tag="PB779_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDE0738064.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(3033..3818)
                     /locus_tag="PB779_000520"
     CDS             complement(3033..3818)
                     /locus_tag="PB779_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HDE0738065.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(3809..4558)
                     /locus_tag="PB779_000521"
     CDS             complement(3809..4558)
                     /locus_tag="PB779_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDE0738066.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            4856..5380
                     /locus_tag="PB779_000522"
     CDS             4856..5380
                     /locus_tag="PB779_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HDE0738067.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            5396..6895
                     /locus_tag="PB779_000523"
     CDS             5396..6895
                     /locus_tag="PB779_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HDE0738068.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(6983..7585)
                     /locus_tag="PB779_000524"
     CDS             complement(6983..7585)
                     /locus_tag="PB779_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDE0738069.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            7689..8645
                     /locus_tag="PB779_000525"
     CDS             7689..8645
                     /locus_tag="PB779_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HDE0738070.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(8950..9906)
                     /locus_tag="PB779_000526"
     CDS             complement(8950..9906)
                     /locus_tag="PB779_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0738071.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            10080..10640
                     /locus_tag="PB779_000527"
     CDS             10080..10640
                     /locus_tag="PB779_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738072.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            10633..11457
                     /locus_tag="PB779_000528"
     CDS             10633..11457
                     /locus_tag="PB779_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HDE0738073.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            11467..12084
                     /locus_tag="PB779_000529"
     CDS             11467..12084
                     /locus_tag="PB779_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDE0738074.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            12102..12785
                     /locus_tag="PB779_000530"
     CDS             12102..12785
                     /locus_tag="PB779_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HDE0738075.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            13468..14751
                     /locus_tag="PB779_000531"
     CDS             13468..14751
                     /locus_tag="PB779_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0738076.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            14767..15654
                     /locus_tag="PB779_000532"
     CDS             14767..15654
                     /locus_tag="PB779_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738077.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            15671..16507
                     /locus_tag="PB779_000533"
     CDS             15671..16507
                     /locus_tag="PB779_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0738078.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            16510..17133
                     /locus_tag="PB779_000534"
     CDS             16510..17133
                     /locus_tag="PB779_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738079.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            17130..18422
                     /locus_tag="PB779_000535"
     CDS             17130..18422
                     /locus_tag="PB779_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0738080.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      18781..18878
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            18994..19575
                     /locus_tag="PB779_000536"
     CDS             18994..19575
                     /locus_tag="PB779_000536"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HDE0738081.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            19578..20885
                     /locus_tag="PB779_000537"
     CDS             19578..20885
                     /locus_tag="PB779_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HDE0738082.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            21301..21789
                     /gene="purE"
                     /locus_tag="PB779_000538"
     CDS             21301..21789
                     /gene="purE"
                     /locus_tag="PB779_000538"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HDE0738083.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            21782..22906
                     /gene="purK"
                     /locus_tag="PB779_000539"
     CDS             21782..22906
                     /gene="purK"
                     /locus_tag="PB779_000539"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HDE0738084.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            22919..24214
                     /gene="purB"
                     /locus_tag="PB779_000540"
     CDS             22919..24214
                     /gene="purB"
                     /locus_tag="PB779_000540"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HDE0738085.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="PB779_000541"
     CDS             complement(24336..25724)
                     /gene="ltrA"
                     /locus_tag="PB779_000541"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDE0738086.1"
                     /translation="MRRPQKTRKLGYHQRASVEHEGYDEVRSTSCGEQRKQDGVENLF
                     GRILDRNNLNQAYLQVVRNKGAAGADGMTVDQLLPYLKEHREELLSNLRQGNYKPQPV
                     LRVEIPKPNGGVRKLGIPTVIDRMLQQAINQVLQPLFEPEFSDNSYGFRPNRSAHDAV
                     KKAKSYYEQGYRYVVDIDMKAYFDTVNHDKLMYFIERKVKDKQVLKLIRQYLMSGVME
                     NGLITTTEEGTPQGGNLSPLLSNIYLNEFDQVLENLGHKFVRYADDCNIYVRSKRAGQ
                     RVMKKSIQFLEEQLKLTVNREKSAVGSPLKRKFLGFCILPTKKGIKIRPHAKAKQRVK
                     SKLKQLTKRNRGRSIQLILKEIKQLMTGWINYYGIGEMKEFMRELNGWLKRRIRQYIW
                     KQWKNPRTKRKNLIRLGIDKAKAYEWSNTRKGIWSVSKSHILHRSLTDKELARQGYED
                     ISLKYQFVHSTY"
     gene            complement(26293..26670)
                     /locus_tag="PB779_000542"
     CDS             complement(26293..26670)
                     /locus_tag="PB779_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738087.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            26926..27654
                     /locus_tag="PB779_000543"
     CDS             26926..27654
                     /locus_tag="PB779_000543"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HDE0738088.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            27654..27908
                     /gene="purS"
                     /locus_tag="PB779_000544"
     CDS             27654..27908
                     /gene="purS"
                     /locus_tag="PB779_000544"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HDE0738089.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            27910..28581
                     /gene="purQ"
                     /locus_tag="PB779_000545"
     CDS             27910..28581
                     /gene="purQ"
                     /locus_tag="PB779_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HDE0738090.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            28582..30804
                     /gene="purL"
                     /locus_tag="PB779_000546"
     CDS             28582..30804
                     /gene="purL"
                     /locus_tag="PB779_000546"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HDE0738091.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            30789..32228
                     /locus_tag="PB779_000547"
     CDS             30789..32228
                     /locus_tag="PB779_000547"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HDE0738092.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            32251..33303
                     /locus_tag="PB779_000548"
     CDS             32251..33303
                     /locus_tag="PB779_000548"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HDE0738093.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            33300..33878
                     /gene="purN"
                     /locus_tag="PB779_000549"
     CDS             33300..33878
                     /gene="purN"
                     /locus_tag="PB779_000549"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HDE0738094.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            33875..35410
                     /gene="purH"
                     /locus_tag="PB779_000550"
     CDS             33875..35410
                     /gene="purH"
                     /locus_tag="PB779_000550"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HDE0738095.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALAFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            35426..36700
                     /gene="purD"
                     /locus_tag="PB779_000551"
     CDS             35426..36700
                     /gene="purD"
                     /locus_tag="PB779_000551"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HDE0738096.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            36822..37736
                     /locus_tag="PB779_000552"
     CDS             36822..37736
                     /locus_tag="PB779_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDE0738097.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(37869..39434)
                     /locus_tag="PB779_000553"
     CDS             complement(37869..39434)
                     /locus_tag="PB779_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDE0738098.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(39427..40878)
                     /locus_tag="PB779_000554"
     CDS             complement(39427..40878)
                     /locus_tag="PB779_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDE0738099.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(40892..41908)
                     /locus_tag="PB779_000555"
     CDS             complement(40892..41908)
                     /locus_tag="PB779_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0738100.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            42128..43216
                     /locus_tag="PB779_000556"
     CDS             42128..43216
                     /locus_tag="PB779_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HDE0738101.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            43270..44796
                     /locus_tag="PB779_000557"
     CDS             43270..44796
                     /locus_tag="PB779_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HDE0738102.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            44798..46003
                     /locus_tag="PB779_000558"
     CDS             44798..46003
                     /locus_tag="PB779_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738103.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            46260..47237
                     /gene="guaC"
                     /locus_tag="PB779_000559"
     CDS             46260..47237
                     /gene="guaC"
                     /locus_tag="PB779_000559"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HDE0738104.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            47501..48925
                     /locus_tag="PB779_000560"
     CDS             47501..48925
                     /locus_tag="PB779_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HDE0738105.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            49386..50495
                     /gene="pdhA"
                     /locus_tag="PB779_000561"
     CDS             49386..50495
                     /gene="pdhA"
                     /locus_tag="PB779_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HDE0738106.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            50498..51475
                     /locus_tag="PB779_000562"
     CDS             50498..51475
                     /locus_tag="PB779_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HDE0738107.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            51500..53143
                     /locus_tag="PB779_000563"
     CDS             51500..53143
                     /locus_tag="PB779_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HDE0738108.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            53151..54557
                     /gene="lpdA"
                     /locus_tag="PB779_000564"
     CDS             53151..54557
                     /gene="lpdA"
                     /locus_tag="PB779_000564"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HDE0738109.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
BASE COUNT        17288 a         9572 c        12012 g        15715 t
ORIGIN      
        1 aatcacttta cataagtttc aaaagtttct ttaatttcct attgttcaat aagtaacaat
       61 gtaaagataa aattaaaaat gttaatacgt attagcaaaa taaaagcttt ttttattgtg
      121 aataaatgaa cataattagg aggagaaaga tgaacttatt tgacattttt cgatcgactt
      181 tgacagatat gtcgattgtc agtgcaatca cttcaacagt ttttattata ttattagggt
      241 ttgtttgtag aaaaaagggg attttttctg aatctgttgg aaaaattcta tcgaaagtcg
      301 tcttaacagt ggctttgcca gcactggcat ttcgagcttt catgcaagat atcaatacag
      361 aattactgat gcaaggaatc aatgtcttga tttggggatt agttatttat attattctta
      421 ttctagtttc aaaacctttt ttcttaagct ataaagggga taagcaaaca acgttgcgtg
      481 tcctgacgat ctttggttct acgacctttt tcggaacgcc tatcgtcagt gcgatttatg
      541 gtcctgtcgg cgtgatgtat tcctcaattt tcaatattgg ctaccgaatc tttttgtatt
      601 cttatggata cataaaaatg agtggcttga agatggaagc taaaaatatc aaagcgatgt
      661 tcgtcaatcc aatcattatc gctacttttg ccggcctttt catttggctg ttccaagggt
      721 atctgccaca agtgtcagtt acaggtgcag aaggagagat aagccaagta gcgtttttgc
      781 gaattgacca gactgcaccg tggctatttc agccgatgga ttatttagct ggtttaagtt
      841 caccattggc gtggctagca atcggcgcaa cattaggtga agtaagcttc aaaaaagctg
      901 catctgaaaa aacttcatgg tattacagtc tagtcaaagt ggtatttgta cctgcattga
      961 atatcgtgat tctagcagtt ttgacggcaa cgaatattct accagtcaat tttgaagcac
     1021 tggcaacaat cgttatcatg atggctacac cagctgcaac agtggcagca gcctatgcta
     1081 tcagttttga tagggaggca cttttagcct ccaatgcatc cttactgtca actatttttg
     1141 ctgtggtact gacacctgta tggatcgttg tattacaaat gattcatggc ataggtttat
     1201 tttcataaga aatggaggaa gaaagtatga gaatcgcatg ttacggtgtt cgtccgaacg
     1261 agatagattt ttttgaaaaa ttgaatattt accattatga tctcagtctt tatgaagaac
     1321 tgttgacaca tgacaatatc gtgtcagcaa aggaccatga tgctgtattg ttgaggggaa
     1381 attgtatagc agatgagacc aatcttgcaa aaatgcagga atatgggatt cgttatgttt
     1441 ttacacggac tgtgggagtc aatcatatcg atctacaagc ggcagctgat tttggtatga
     1501 cagtagcccg tgtaccatcg tattcgccaa atgcgatagc agagttatct ttgacttttg
     1561 ccatgatgct tttgagaaat actgcgtata cgacgatccg aacatctttc aaagattttc
     1621 gagtggatga gcaaatgttt agtcgtgaaa tcagaaattg cacagtaggg atcataggaa
     1681 caggcaggat agggttgacg gaagctgttt tgtttaaggg actaggagcc aaagtgatcg
     1741 gctacgatat tcatcagaca gaagctgcta aaaaagtatt gacgttccac tcgcttgaag
     1801 agttattagc caaaagcgat attgtcagta ttcatgtacc tcatatccca ggtgaaaacg
     1861 atcaaatgat caatgaagga tttttagctc aaatgaaaaa aggtagcatc ttgattaata
     1921 cagcccgtgg agagcttcaa gataatgaag ctattttaag agctttgaaa agcaatcatt
     1981 tagctggttt tgcaaccgat gtttttgcaa atgaaacaga ggtttttttc cgatccttca
     2041 agccatggga gacgattcca gaccctgcta tccagcaatt agtagaaatg taccctagag
     2101 ttcttgtaac cccgcatgta ggttcaaata cagatgaggc attatcaaat atgatttcga
     2161 caagtttcga gaactttcgt gaaataatag aaactggaaa aacgaaaaat gaggtatctc
     2221 ttcctaaagc ccgtcaatta agataagaaa acatggatat tcgtcaataa aatgtttaaa
     2281 aatagtccaa gtaaacagtt gttacttctg tatacttgga ctattttgta tgggataatt
     2341 cgatgactca acagtaatct gtgagctttt tccgcccatt ctttgtcaat tcataacagg
     2401 ttagcggccg gccgatttcc aaatatttga ttctttcgtt caatatatct tgttctacta
     2461 aaaaattcaa atatttcttg acggatatac gtgacagtga gcttttttga gccagttctt
     2521 ttgttgaaaa aatagtatct tcttttagaa taaatgcact tatttttttt aaagtcagtt
     2581 ttgacagacc tttaggcaaa tcgatgaatg atggtatttc gtgaatggga gtggtgtggt
     2641 tgaatacttg atcgatcaat ttctgatcgg ctttttcagt cgtttggatt gtctgagaga
     2701 aagcaagata cttttcgatc gccagctgaa aacgttgcaa agtgaacggt ttgatcaaat
     2761 aatctaaggc accgtagcgg atcacattct ttatggtttc gatatcatct gcagcagtga
     2821 tcaaaatcac tgggatatca tttccttgct gtctaagcca agataaaaaa tggataccac
     2881 tttcgccagg catgtataca tcaagcagca gcagatctgc gtttttttgt ctgaaatatt
     2941 tttttccttc ttctacattt ctgaaacttt cgattacgtt catattaggg atgctttcca
     3001 caaaagtacg attcaattct gcaaccattg gatcatcttc gattatcagg acatttgtca
     3061 tcattttgat cttccttttt tggtaattct agatagacga ttgtaccgcc atttgtttgt
     3121 ttggaaaatt ctaaaaatcc accgtggcgt ttgacgattg aatggatgag attcaatcca
     3181 aacccacgat tgattccctt cgtcgaaaaa cctagcgtaa atattttttc tgagatttct
     3241 tctgatatcc cgacaccgtc atcgcagacg gtcacgatga atacttcagc ttctgtgtca
     3301 tagtttaaat gaatccggac ctgtccgttt ctttcatgtt tttgtagcac ggcttctttt
     3361 gcattatcaa gtaagttccc taacacttgc aaaagtgaat ggatggagtc atccatctcc
     3421 attttaggga taaaagaatc gctttctaac agcatttcaa cagattgttc tttggcttcg
     3481 tttattttgc ctaataaaaa accggcaatt gcaggtactt tgatcagact tgagacttgg
     3541 ccaatctctt ttttataatt ttgatttagc tgctggataa aatgggtgac ttcttcatac
     3601 ttcttcaaat caatcaaacc agaaatgaca tgaagtttat tcatgaattc atgggtttga
     3661 gctctcatgg agtttatata ttgtttcgtc cccccaagct cctccattaa tttcattact
     3721 tctgatcgat ttcgtaaagt tgcgactgct cctaaaaaac ggtcattgct aaaaagaggt
     3781 gtaacgctag aaatagtttc tatcccattt aaatacatgg attgagtccg aacggtcgtt
     3841 tgatgctcaa tcgtctcttt aaacaaaacg tcatatagat tatcactgat ttttttccta
     3901 cttcgaaatc caatagctgc tctgtttggt agaaaatgtt ttttgcaggt gtattgatca
     3961 agaggatagt tttatcagaa gagatggcta agattccttc atctacttca ttttcgataa
     4021 tcgttttttc acttaactgt tctgctattt cttgtggttc aagtccaagc agtacttttt
     4081 tcattttttg ggcaagaaaa acggcgccta tgatgcctac gctaagtcca ataatcaatg
     4141 aaaaaacaat cattttttgt ccatctttga cttgattgtc aatcgtgttg tttgttaagc
     4201 caacacaaac tgcaccaata atctcttgat cataataaat agggacgaaa tagcggaagc
     4261 cgaaccctaa cattccttct ttttcagaga aaaattcttg tcctccaatc acttttttca
     4321 catcttcatg acttgagaaa ggaagaccga tgtaacttgg gtctgcgtga gaatatcgaa
     4381 tgccttcagg gtccatgaca acgataaaat ctaaattcga tgcaatcatg atttcatttg
     4441 ttattccttg aatcgcatgt gtcgggtcac cagtctgcag ctttttttgg atgagtttat
     4501 cattggcaac gattttagca atgctagaga ttttatctga cacactagat cggttcatcg
     4561 aaagaataaa attcctgatc aatatggcag aaacaatcaa agaaacgaat gtggagaaac
     4621 aaacgacaag gatgatcgtg ttctggagct ttaatggttt tttcttaaaa aaaggaaaca
     4681 taggctacct cgaaagaatt tattgtgaaa attttaacat gaaaacaaaa atttaacaaa
     4741 ttgtcaacga taaacacaac cttcctataa aaaacaccac tgagtcggta aaagaagcta
     4801 tacagaattt tcaaacattg gtatgataga cgtagaaatg gaaggaggcg tgtatatgat
     4861 agggggaatc gcacttgaga cgatttattg gtatacattg ctgatttgtg caggattggc
     4921 agtcctattg attatttttg gagatgtatt cgattttgat ggcccgcttg atccgatgct
     4981 tattatccct tggttaactt tcacaagctt atttggtttt ctaggtgagc gtttaacaga
     5041 tcaatcatct ttatttttat ttattgctag tggaggcata tcgatagtgt tggtattttt
     5101 gcttaatttc tatatattga tgccgatgaa acatgccgaa tcaacgatgt cgtcttctga
     5161 aaaaactctg gaaggacaag tagctgttgt gatcacaccg atccctgtac gaggtatggg
     5221 agaaattcag ttgaaaagtg ttaccggttc cattagtcgt ccagcttgtt tttacagccc
     5281 ccaagaacag acagctgagc ggggaacgaa agtattgatc attgagatca aggaaagaat
     5341 ctgttatgtc atgccttatg aaagcatgat aaaagcttaa aggagcgtgt gttaaatgga
     5401 aataccagtt gtttttatcg cgatcgcaat cgcagctttg attttactga tgttgctgat
     5461 cgtctttgta gcgaagtacc agacagcaaa accggatgaa gcgttgatca tcagtggaag
     5521 ttatttagga agcaaaaatg tgcacattga tgaaagcaat aacaaaatca aaattgtgcg
     5581 tggaggtggc gcattcgtct tgccagtttt tcaacgttcg aatcggatca gtctattatc
     5641 gagtaaattg gacgtctcca cccctgaagt gtatacggaa caaggcgtac cggtgatgtg
     5701 tgatggtact tcgatcatca aaatcggttc atctgtagaa gagattgcta cagcagcaga
     5761 acagttttta ggcaagacaa gagaagaact ggaaaatgaa gcaagagaag tattagaagg
     5821 acacttgcgc tcgattcttg gttctatgac tgtagaagaa atctatcaaa atcgcgataa
     5881 gttcagtcaa agcgtacaag aagtcgcttc tgtagacctt gcaaaaatgg ggttgatcat
     5941 cgtttctttc actatcaaag aggtcagaga caaaaacggt tatcttgact ctttagggaa
     6001 accaagaatc gcccaagtca aaagagatgc agatatagca gaagcggaag ctctaaaaga
     6061 aacgcgtatc aaaaaagctc aagcagaaaa agaatcacaa gcagctgaat tacagcgaca
     6121 aacagagatc gcagaatcat taaaagaaaa agaactgaaa ttagcaacct acaaacaaga
     6181 acaagatgtt gctaaagcaa aagcagacca agcctacaat ttagaaagtg cccgagcaca
     6241 acaacaagta atcgaacagg aaatgcagat taaaatcgta gaacgtcaaa aacaaatcga
     6301 actggaagaa aaagaaatca cacgtcgtga aaagcaatat gattcggaag tgaagaaaaa
     6361 agcagatgcc gatcggtacg ctaaagaaca agaagcacaa gctcaaaaag tcaaagaagt
     6421 gactgaagcc gaagcagaac gattccgtgt ggaagcactg gcagaagcgg aagccaataa
     6481 gacacgttta gctggacaag cagaagccga agcagcacta gcaaaaggaa aagcagaagc
     6541 cgaagcaaaa caaaagatcg ccaatgcctt caaggaatat ggcgaagcag ctgtcttgag
     6601 tatggttatc gatatgctac cgcaattgat gcgcgaagca gcacagccgc taggaaatat
     6661 cgaaaaaatc tctgttgtcg atacaggaag cagttcagga gaaaccagtg gagcgaaccg
     6721 agtgacaaat tatgccacaa atttgctttc ttctactcaa gaaacactaa aagcgacaac
     6781 aggacttgac ttgaaggaaa tcgtagagaa tttgtcgaca cgtgggacta ctagccaagt
     6841 aaatatgtat gaagcgccaa aagaggcaga acaaaactcg atgaaggaag aataaagtag
     6901 tacacttcac cgttcaatca aaaatggagg aagacttttt aaagttcttc tctccatttt
     6961 tttattttat tgcaaaagaa aattagtcct cgctattttt cttttgtttt tggatcttag
     7021 cttctatctc ttgtaaattt gttcttagca atcgttcttt cttttggagt tcgaccaaat
     7081 cttctgatag ttcttccttc ttttctgttt caggaggacg aagaaagaaa ttgataccga
     7141 ttgcaatgaa tgtccctata aaagtatcta gtacacgttg gatagcatac aaagcggatt
     7201 cgccttgagg gatgctcaac gcaatcagca acaacgtagc tattgcggaa atgataccgg
     7261 aattattgtt aataccatct gacacgacga tcacaataat aactagaata ggaagcaaga
     7321 tcaattctac caaaaaatca ttgtgaaaat agcttttgac aaaaaaataa atgatagcta
     7381 atgtaccacc taatgtattg ccgatgatcc tagactttcc aaaagaaacg gttgtagtca
     7441 agtcctgacg caaagaaaaa acagcagata atgcagcaat catcgggatt cctcgttgag
     7501 tcaaatgaaa aaacaagata cataaaaaaa cagctaaggc acttttgatc gtacgcatac
     7561 ctagtcgaaa acggccaaat tgcatagaga ttctcctttt tggtcttttt actatcatac
     7621 ctaaactttt gtctgatagc tagtttttca ttattcaagt ataattaaaa taaaaaaggg
     7681 ggaagtaaat gcgtatagga atgcgaacag tcaaaacagt gatcagtgtc ttcttttcga
     7741 tggtcacagc gggtagctta tcgctgttgt attggccagc tgcagggatc attgcattat
     7801 taagtgtagg aaataccaag cgctctacat tgcgtacggg catgaatcga atcgcagcct
     7861 ttatattagc tacggcaaca gcactgttca gtttttttgc tgttgggtat actatttttg
     7921 gcttcagtct ttttttattc ctgttcatcc cgcttgcctc tcgcttcaaa ttaaccgaag
     7981 ggatagtagt aaattcggtt ttggtcactc attatttagt ggaggaaaac atgtcttggc
     8041 agctgatcgg caatgaagcg ggattaatgg cgattggatt agtatttgct ttgcttgcaa
     8101 atgtttacat gccagatcgt acgaagcagc tgaaggaaaa ccaaatacag atcgaaaaag
     8161 aatttcgaaa tattttgaga caaatggcag aatttctttt atcagaaaat aaagaagatg
     8221 tgcagatcaa atgcgaacat ttactgacat tcattcgcga aagccaagaa gatgccagag
     8281 aacatcaaga aaactactgg ctcagacagc cgctatacta cgaaacttac ttctctatga
     8341 gaagagcaca ggccaatgtg attaaagaca tgctggaaaa tctagagaga atccagcaac
     8401 cagcttatta tggaaaacat atctatggtt tattgattta tactgcagaa acattttcag
     8461 agtcaaatga tggcagacaa attttaacac gtattgaaga agtttatgta ttgtatcggc
     8521 aaatgcctct gccgactagt cgccctgaat tcgaggatcg agcagaattg ttccagtttt
     8581 tgcagtcttt taaaagtttt attgaaatca aggcagaatt ctcccaacaa aaaatccaaa
     8641 aatagaggtt gtgaattcag ctaatattca ggtcaaaaag ctgatttcac aacctcttct
     8701 ttaaacggtg ttctcctgtc aactcctcgg tcacaagtca caatattcaa caaacatgag
     8761 aagctgtttt ttgaaattgc tccttgtgac tcggagctga acggtaggct cacaacctct
     8821 ttcttaaacg gtgttcaaaa gctttcctct gcggtaataa gtccagccaa acgaaaaata
     8881 ggaggagcta tttttgtttg gctgttctta ttacttgatg cagaacagct ttttcacaac
     8941 cttttaaaat tacatatttt tccatagaac ttgcatttga tccaagattt cgatgacatc
     9001 ttttgtcaag aagagagagc gattgggcaa gtcaccttca atcatgtgta ccatattctt
     9061 tatttcgtaa ttcattgctt cagatgtatt cccgctttcg atgaattcct ttgtaccatc
     9121 tgtaaataag atctccgcac gatcagcacg cgggtaatca gcaatcgtca cataaccgtt
     9181 ctcaaaggca acgataccga cttttggcat ttttgcctga aaagtcaagc tgacagcagc
     9241 aagttcattt tctttgttac gcaagatagt gacggattgt tcgtccacgc ctgtttcaaa
     9301 aggaaccatt gtagaggcaa ctacttcagg ttgagagctc aaaaagaaac gagcgaaaga
     9361 tacagcatac gtaccgatat ccaacagagc tcctccagct aattctggat tgaagaaccg
     9421 gtttttaggg tctggttctt tgtaactgcc gaaaggtgct tggatcattt ttaaagcccc
     9481 cagttttcct gtatccatta ttgagcgtaa ctgctgataa agtggcatgt tgaagattgt
     9541 catcgcttct gctaagatca aattcttttc ttctgctaag cgcatagcgt cagccagttc
     9601 ttttttattc atcgtgatgg ctttttcaca tagaacgtgt ttgcctgctt ccaatgctgc
     9661 caagatatgg tcgatatgct gtctatttgg tacagcaatg tacacgatgt cgatttcagc
     9721 atcgtctaac atttcttgat agcttccgta agcttttgga atattgtaac ggtgagcgaa
     9781 gttttccgct ttttctgaag ttctggaagc aactgctgtt agttcgctcg tctcttgatt
     9841 gaagctttcg gcaaactcat gtgcgatggt accaagacca acgattcccc attgatattt
     9901 tttcatctga aaacgctcct tcatagttgg attgagtttc ttgtctgtct attattataa
     9961 caaaaatcac gaagaataaa gaggagagga cttgaaacat taaaaaaaat gaaagcagcg
    10021 atttaagagg tgctttttga tcaaaactta agtagaatag ttaaaaggag gggataaacg
    10081 tgcatcaagt atatattgat cttattatga gtgtattatt agaacagttt gaaactgaaa
    10141 aaaatttttt agatgaatac ttgctgatca gtccagaaca atggcaaaaa tggaaagatg
    10201 gcgagaaaaa tctgccatct gaagcgatgc agaaagtaaa aaatcttttc actgattatg
    10261 aatggatgct aacgcaaaag attttgcgtc aaacgattat ttttcccgaa aaacgaaacg
    10321 ttgccgttgc agagtacaag caaatcaaaa cacgcatcgc gcaaaaatgg cttagcagca
    10381 aagcagcaaa agtcgagctg atccctttga aaaataatca gcaggctggt agataccttg
    10441 acttgaaagt aagtattcaa tatgatgaat ggggctatga tgatattttg aattttcgtc
    10501 tgccagcaga tgttcaaaaa cagatcgaag gagaaaaaat cgaacttctc gattgggtga
    10561 atgaaaatct ggaagaaact tacgttcatg aggcgaatgg ggaacgtgaa gaacaacgaa
    10621 aggatttttc aagtgaataa atttttagga tttggagcag ttgtgattat gatcgcagca
    10681 atgggctatg ttatttttag cgatgatgat tcgcatgttc aagccggcaa tcaagcagtc
    10741 gaacgaacaa gcaccaaaac aactgctagt aaagaaaaga acagtcaaac aaccagcagc
    10801 aaggtaaagg acaaagaaac aaaagatcgt acgtccaaac aattgccaga tgttaaaaca
    10861 gacgattgga agctagtttt ggttggtcca gatcacaaat tagaaaaaga aattgatgag
    10921 tctactcaat tggcatcatt aagtaacgga tacttgatcg acaaacgcat tgctccagaa
    10981 tatgaagcat ttgccaaggc tgctgaagca gctggatttc cattagtgat ggtctcagct
    11041 taccggtctg tatcatccca acaacaagtt ttcgaacaaa atgtccaaga tgtgatgagt
    11101 cgtcaaggtg tatcagaaga ggaggcgaca aagattacta aagaaacgat tacggagcca
    11161 ggatacagcg aacaccacac aggtctggca gtcgatgtcg tcgatcaaaa ctggtacaac
    11221 agttatcctt ctactgtatt ggatgcaagt tacggagatc agcctggagc taaatggatc
    11281 gcagataatg ctgcgcagta tggatttatc gttcgttatc caaaaggaca cgaagatata
    11341 actaagatca catatgaacc ttggcactta cgttatgtcg gtaaagaaaa cgctgagtat
    11401 atcaccaaac accaattgac gctagaagaa tatctgaatg aattaaatga aaagtaggaa
    11461 ttgatcatgg cgaaaaaaaa gtggaaaaag caaaagcgca agaatatccg ttggccagca
    11521 gtggttgccg gtgtagcagt gatactctta gcctttgttt tttccttgaa gaatctgtct
    11581 tctcctttta ctgataatca gcaagaaaat gaagcgcaat cccatcagca atttattgaa
    11641 cggcttgttc cgcatgccca agaactacaa gatggttatg gagtgcttcc tagtatcatt
    11701 ttaggacaag ctatattaga atcaaattgg ggaaaaagta ccttggctag caaatacaat
    11761 aatcttttcg ggatcaaggc ttatggggat cagaagaaag taagcctgga aacaaaggaa
    11821 tttgttaacg aagaatggat aactatccaa ggagacttca aagtgtatga ttcatgggaa
    11881 cagtccatgg atgaccatac acaactgttc gtccaaggag tagattggaa tcctgcgctg
    11941 tatgaaaaag tgattacggc caccaactat caggaagccg cacaagcatt gcaagatgca
    12001 ggttatgcga cagaccccgg ttatgcgcaa aaaatcatcc aggtcatcga gacgtatcaa
    12061 ttgaatcagt atgaccggag atagcaaagg agaagtggct gatggcagaa caatttacgc
    12121 cagaaatcat gacggaattg agaaaagata tcgtaagagt accggaaatc attttagaag
    12181 caagcgggat caagatattt ggaaaattga tccgttcgat catctttact acggatattg
    12241 cgatcatacg taatacaaat gcgaatgcag taattgctgt gtatcctttt acacctcatc
    12301 cagcgattac taaaagcatt attgaggcag ctgacattcc agttttctcc ggtgtaggtg
    12361 gtggtttgac acaaggtgct cgttcttcct acatgagcat gttcgcagaa gcgcaaggtt
    12421 cgttaggggt cgttttgaac ggtcctacgc ctttagagac agtaaaagaa gtttgtcgag
    12481 tagttgatat tccagttatc agtacggtaa cgtcgaaata tacagaaata gatgaaaagt
    12541 tagcagctgg tatttcgatt atcaatatca gtgcaggtaa agaaactgca gaagcagtac
    12601 gccattttcg taaaaaatat cctgaacttc ctatcattgc gacaggtggt ccaacggaag
    12661 aaagtattgc tgagaccatt caagcaggag caaatgccat cacatatacg ccaccaagta
    12721 gcggagagct ttttagtcgt aaaatggaaa aatatcggga aactgagaaa aagaatcatg
    12781 aataacaggt gagaatcaaa agacgaggaa gagcagatag tggctcttcc tcgtcttttg
    12841 tactccagta ctatttgttc agaattcaaa aaaaagagaa atttttttgt ttttttacct
    12901 gtaatgtaca taagaagagt taaaaccttt tgttattatt agcattctaa caaaaaaatg
    12961 tcttgattta ttgaagcgct ttctatagaa tgaaaaacga ataaaaacta aaaaaggcac
    13021 ccgacaattt agtagcagct aaattgtcgg ggcttgaaaa gtcagcggga actgaccaat
    13081 caagttgcca tagtcaatgc ttgtgcatcg acgtgtatat tgtacctaat ttcatacaga
    13141 attactagtt atttttctgt tttttaggga agagcgcaca cgaagaagca tgcttattta
    13201 gctatgtcaa ggatattggg cagttgtctg atatcctttt ttctttgcgt aattatcctc
    13261 ccatcattga agcaagaagt gtttttagcg atgaaagaag aatcagcact atctaatttt
    13321 tcttgaaagt attgagttgt tcatcctagg cagaacgata aggcaagtct tggtttttat
    13381 tccccttgaa aaagatcgtt taataaatat gttctgtata aaaatacagt atattgaaaa
    13441 ataacaatgg aagtagaggt gcagagaatg aagaaaagaa tgagaatcat cttagcttta
    13501 agtgttatgt tattcttctt gacggcttgt gggcaagaag atgacaaaaa aatcacgctg
    13561 aacatggctt ggtggggttc gcaagtccga cacgatgcaa cagtaaaagt aatcgagctt
    13621 tatgaagaaa aaaatcccca tgtgacgatc gattatgaat tttatgatta tgaaggatat
    13681 tacacaaaat taggtacact agcagcatca gatgatatct gggacatttt ccaactgaac
    13741 aatcaatttc ctcaatacat caatcagatt gaaccattag atgaatatgt ggagcaaggg
    13801 ataattgata tttctaatgc agatgaatcc tatttagcaa cgacgactta cgacgggcaa
    13861 ttagttggac tgtctaacgg ggtgaattcg tttgcgattg cttacaataa aaatatattt
    13921 gaacaattaa atatccctga accagcttca aattggacat gggatgaatt tgaacaaatc
    13981 agctatcaaa tcactgaaga attaggaatc tatgctattt caagattcga agattttata
    14041 gctggctgta ttattcaaat accacaagtt gagaaaggat tgaattttta taatcgggaa
    14101 gatctatcta acagcttggg atttgaaaat ccagactatc taacagattt tttccagctg
    14161 cgtaaaaatc tggtagacaa aggggcccat ccagaaccag gtggtggagc tgcaagtacg
    14221 acggatctgt cttttcaggc ggttagggat agagaagcgg caatggtgtt tctatcaagt
    14281 aaccagttga cagaaatatt gtcaggggct cctgaagata tggagattca gttgattaat
    14341 ccacctcgca gaaaagcaga tggagaatct ggtatccctt tacgttcttc gcaaatgctg
    14401 agtatggcaa aaagctcagc ccataaagaa gaagctgcta agtttattga tttctttcaa
    14461 aacagtgaag aagccaatga aattttaaaa ggagaacgtg gtgtaccaat catgtcgaat
    14521 attcgagaac agctcgctcg tgcagatgat gcaactttgc aagcgacatt tgattattta
    14581 gaaatgattt ccgatatgga caacggcgaa gtgaatgtct ttgatagtgc tttgaatccg
    14641 gaaattcaag accaatacaa tcttttagtt gaaaaagtca tttatgaaga agtaacagca
    14701 gaagaagcag cagagagtct ttatgagttt gcgtcaaaca ttctaggata gcagcaggag
    14761 gaaggcatga aaaaagaaaa actaaaacgg ttcttggatc aagacaatgt ggtcggttac
    14821 gtatttgctt ctccattcat cctaggattt ctattgataa cagtgatacc gatgatcttg
    14881 tcactttatt attcgttcac cgattatcgt ttgggaaatc cagtctcatg gatcggcttg
    14941 gataattata taaagatgct gagtgatgcc cgttttttga actccatccg agtcactttt
    15001 ctctatgtat ttgcatctgt acctgtgaaa ctgatctttg gtctattgat tgcttatctt
    15061 ttaacgagga atatcaaagg aacgactttc tttcgttctt tgtattatgt gcctagtttg
    15121 atcggtggca gtatttctat cgctctagtt tggcgggagt tgttttctaa aaacgggtta
    15181 gtgaatattt tcctggaacg attaggcgca cctgcgcttt cctggtttag cgatcaaaaa
    15241 ctggtcatga tccctcttgt tttgatgtct gcttggcaat tcggttcggc aatgatcatc
    15301 tttgctgcag gtatcaaaga gatcccaggc tcgtattatg aagcggcaga gatcgatgga
    15361 gcgaacaaat ggcagacgtt ttacaagatc acgttacctc ttctttcgcc gatcattttg
    15421 tataacttgg ttatgcagac aatcgcggcg tttatgactt ttacgcaggc atttatcatt
    15481 acccaaggtg gtccgaatga tgccacgaac ttttatgctc tttatgtgta taaccaagct
    15541 ttttctttta attctatggg gtatgctagt gctatttcgt ggatcatgct gttgattatg
    15601 ggagctgtca cctttctgat tttcaaatca tcaaaaaaat gggtcgttgt gtgaatgaga
    15661 ggaggaagaa atgaataata cagtaacgaa atggtttcaa tacggtttta ttttgctatt
    15721 aggtctagtc atgatttatc cggtcttatg gatgatcgca ggttctttta aaacggatca
    15781 agagattatg agtggttcgc tgaatttgat tccagagact tttcaatggg aaaattacgc
    15841 aaaaggatgg gcggggtttg ctggaatttc attttttact ttctttagga attcgtttgt
    15901 catctctgca gtttcgacga tagggacagt tctgagctcg acttgtattg cttacgcatt
    15961 atcgagaatc gatttcaaag gaaaaagatt ctggttcgtc gtcatgttag taacgatgat
    16021 gattcctgca caagtgattt tgattccgca gtttattatt tacaatcggc tgaatttggt
    16081 tgggacgtat gtgccgctga ttttaccaca tttttttgga caagcatttt tcatttacca
    16141 gatcatgcaa ttcatggtca gcatccccaa agagttagat gaatcagcga ttattgacgg
    16201 atgcagcaag tatagtgtct ttaccaaaat tatttttcct ttgctgaaac cttcgatcat
    16261 cacgacgatc atcatccagt tttattggaa atgggacgac ttcatgggac cattgattta
    16321 tttaaacaag ccgagatctt acacggtatc gattgccatc aaattatttg cagacgctgg
    16381 atctagtacg acttacgcga gtatgtttgc gatgtctacg ttgtcgctgc taccggtttt
    16441 tctgattttc ttattcttca ataaatatct tgtccagggg atcagtacaa gcggtctgaa
    16501 gggctgaata tgaaaaagcc aatagaagag atgtttcttt acaagctcaa ctactatgtc
    16561 tgtcggattt ttttaaccag tcttatcagt aatgctcttt tcgctttagt tctaggatgt
    16621 ttgttcactt taggattagt gctgtctgct cgtgttgtct atctgattta ttttttgatg
    16681 atgtatcctt cttattatct atctgtccat tacttggcag aaaaaaaggt atgttggagg
    16741 aaaggaaaaa tcaaacggat gtgtttcatc attacgttgt ttcagctgtt tgtcattatt
    16801 tttgcagttg attggtattt attagtggga aagattggag cttggtatct gattcctttt
    16861 ctattgtgtc tgttgctttt tgtatcccat agttttttta gtacgctaat tgatatctgc
    16921 aaagaagata aagcagatag tcttgtttat ttgatcaaaa ggaatatctg gctgttgtca
    16981 aaaaacgtca aggggtttct gtggtattta tgccttttgt atggactgtt ctggtgtata
    17041 cagcatgatt ttttactcac tgcattactg tatccagggc tgccatttgt cacagtattt
    17101 tgcttaaaag aaaaggagaa tgactttaaa tgaagaaaaa atatgtacaa gtcggacttg
    17161 gtgggagagc gcgttttttt tatgaggcaa ttgcctctac gtatcatcaa acttgtgaac
    17221 tagtcggttt ttgtgatgta tctcaaacaa ggatggatta tgcaaatcgg atacttgtga
    17281 acaagtatgg acagaaaaaa gtaaagacat gtatgccatc acaatttgag caactactgg
    17341 atgacgtacg gccggctgaa gtcattatta cgtcagtaga tcgaacgcat catgattata
    17401 tcattcgtgc aatgaaaaaa ggatatgatg ttatttgcga aaaacctctg actatcgatg
    17461 aggaaaaagc tcaagaaata ataacggtcc aaaaacagac gggaagaagc ctgcgagtca
    17521 cttttaatta tcgttatgca ccgtatcaca cgaagataaa ggaactgata gaaagtgatg
    17581 tgattggtga tgtgttttct atccacttcg aatggctgtt aaatacgcaa cacggggcag
    17641 attatttcag aagatggcat cgaaataagc acaatagcgg cgggcttctt gttcataaat
    17701 ctacccatca ttttgatcta gtgaattttt ggttgaacag ccgtccccaa aaggtatttg
    17761 cattcggtgg attaaacttt tatgggatgc ataatgcgga gaaacgcgga gtagaaatat
    17821 tttacagtcg atgctatgga agcgaactag ctaaagctga tccatttgct atagacctgt
    17881 cagccaatga ggaattgcga gaaatgtatt tagaagcaga aaaagacagt ggatatattc
    17941 gtgaccgcag tgtattttcc gatgatatct ctattgaaga tacactaggc gtaacggtca
    18001 aatatgaaac tggtgcgatt ttgacgtatt cgctaaacgc gtatatgccg tgggaaggat
    18061 tcaatgtttc tttcaatggc agcaaaggac ggatcgaaat gaaagtgatc gaaaagtctt
    18121 acatcaatgc aggtggagat aaaaaggatg aaggagcagc cgttcttcag tccatccatg
    18181 tctatccgat gttcggtgag ccatatgagg taatcgtcga acaagaagcg ggcggacatg
    18241 gcggaggaga tccgcgttta ttagatgatc tatttggtga agaaaaagaa gaagatccgt
    18301 ggaatcgggc agcaactcac gtagatggta ttttgtcgat tttgacagga atcgcagcaa
    18361 atcattctat tgcttcagga aaagcagtag tgattgacga gcttgtcagc ttaaaagaat
    18421 aagaatagat ttacggaaat tacttcccgt agtttataaa atcttgcctt attgccgata
    18481 ggctgtcttt tgaacactat ttattcggaa aaaggggcta tgacatgctt tttgtcatgc
    18541 cttcttttta tgtgggctgc ttttttagat aggagaaaat aaaaataact atttaaaccc
    18601 gaacaaaaag gaataatgca ttaaaaatca ttagatttta caaaaaaata agtaaaccac
    18661 gttgtcagtt tcagaaagta gtgttagact gttttcaata tttgaaacaa cattttttat
    18721 tcaaatatgg caaactgcct tcacgtgcaa aacagttgca agaaaatgaa tttacactat
    18781 tattagtttt acatacctac ttatatatcg tcataatatg gatgacagtt tctagccagt
    18841 accgtaaatg ctggactata agtaaaagat tggctatttc acccttcttt tcttatgata
    18901 aagtggaggg tgtttttctt taacagaaac atagtaggtt tttgcacaaa agcggttatt
    18961 tcggtattaa taaatgataa aggagcaaat aaagtgaaag aattagttga acgtattcaa
    19021 aaagacggac gtatattagg cgagggcgta ttaaaagtcg acagcttcgt cactcaccaa
    19081 gtagaccctg tattgatgga acaaatggga aaacggtttg cagaagtatt taaagaacaa
    19141 ggaatcacga aagttgtgac cattgaagct tctgggatcg caccagcttt atttgctgca
    19201 agagaattag atgttccaat gatcttcgct agaaaagcaa aaagtttgac gatggatgaa
    19261 gaattattga cagcttctgt ttattctttt acgaaacaag tgacaagtac gatttctatt
    19321 tctcgtaaat ttttatcttc agaagacaaa gtattgatta tcgacgattt cttggcaaac
    19381 ggacaagcgg caaaaggatt gatcgaatta tgccagcaag ctggagcgca agtagaagga
    19441 atcgggatcg tcatcgaaaa gtctttccaa gatggacgtc agttacttga agaaatggga
    19501 ttgagagtcg tttctcttgc gcgtattgct tccttgacga atggacaagt tgagtttctt
    19561 gaggaggacg cataatcgtg gaaaaagaaa cacaaaatgg aaaagctgcg gttttagggc
    19621 tgcagcatct gctagcgatg tatgcaggag cagtagcggt gcctcttttg atcggtacag
    19681 gactaggctt taatcaagaa cagatgactt atttgatttc aattgatatc tttatgtgtg
    19741 gattagcgac attattgcaa ttgacagtta accgattttt cggaattggc ttgcctgtcg
    19801 ttttaggatg tgcgatccaa gcagtagctc cactgatctt gatcggaacc aatgaaggag
    19861 taggagctat ctacggatct attatcgctt ctgggatctt tgttgtgtta gtttctggtg
    19921 tcttttctaa aattaaaaaa ctattccctc ctatagtaac aggaacggtt atcaccgtta
    19981 ttggtttgac tttgattcct gtagcaatcg agaaaatggg tggaggtaat gcaacagcag
    20041 ctgattttgg tgacaaaaca aatctgctac ttgcatttgt gacgattctc ctaattgtag
    20101 gcgtgcaaat gctggcaaaa gggttcattc gttcaatcgc ggtattgatt ggtttagtcg
    20161 gaggaagcat cttagctgct ttcatgggaa tgattgatct gagcgcgatt ggagatgcgc
    20221 cgttgttcca tgttccacaa cccttttatt ttggtaaacc aactttcgac gtatggtcga
    20281 ttttactaat gatcatcatt tccatggtca gcatggtaga atcaacaggt gtatattttg
    20341 cacttggtga cattactggg aaaaatgttg gagaagaaga attgaaaaag ggatatcgtg
    20401 cagaaggact tgccgttatc ttaggcggta ttttcaatac attcccttat actggctttt
    20461 ctcaaaatgt cggattggtt caactttcgg gaatcaaaac aagaaaaccc atctatttct
    20521 ctgcattctt cttgattgtt ttaggattat tccctaaaat cggtgcgtta gcacaaatca
    20581 tccctgagcc ggtacttggt ggaggaatgt tagtcatgtt cgggatggtg gcagtccaag
    20641 gaatccgtat gctgttggaa gttgatttca gcaatgataa aaatctattg attgttgctg
    20701 tttctgttgg atttgggctg ggtttcaatg ttacgccgac attattcagt caaatgccgc
    20761 aaacattgca aatgttcact ggaaatggca tcgtaatgag tagcattacg gctatcatat
    20821 tgaatttgat ctttaatgga ttgaaaaaag atgaagaaat attggaagaa gccttcaaga
    20881 agtaatagag caaaagaaag gttgtgaaat cagcgttttg acctgattgt tagagaaaca
    20941 aacggaaaaa tagttcctcg tattttgccg tttgtttgag ctaataccga gggtcagctg
    21001 attgaacacc gttgaaggaa gaggtcgtga gcctgccgtt catctccgag tcacaaggaa
    21061 caatttcaaa aaaaagcttc tcatgtttgt tgaatattgt tccttgtgac cgaggagttg
    21121 gcaggagaac accgtttatc cataaaaagg aatgtgacct aacttttgtc acattccttt
    21181 tttttatctt taataaacac gaacaataaa atgtttttct ttgttaacat tcgaaatttc
    21241 tttgacatca aaaaaagtga ttgttaaaat atgaatgtag aaaaactggg aggaaaaaca
    21301 atgacagcaa aaatctctgt gattatgggg agtacttcag attgggaaac aatgaaagaa
    21361 gcatgtcaaa tattggatga attcggtgtg tcttatgaaa aaaaggtcgt ttctgctcat
    21421 cgaaccccag atttgatgtt tgaatatgca caaaacgctc gaaaaaaagg aatcaaaatc
    21481 attattgcag gagcaggggg agccgcgcat ctgccgggta tggtcgcatc aaaaacaact
    21541 ttgccggtta tcggtgtacc ggtccaatca cgaacattaa atggtttgga ttcgcttctt
    21601 tcgattgtcc aaatgcctgg aggagtacct gtagctacta cagcaatcgg aaaagcggga
    21661 gcaattaatg ctggactact tgcgatacag atgctttcca tgtatgattt agaattggag
    21721 gctaaattgg ctgaaagacg ttcaatgttg gctaaaactg ttatagaaag tagtgatcaa
    21781 cttggttaaa cctttgttgc ctggttcaac gatcgggatc gtcggtggcg gtcaattagg
    21841 tcgtatgatg gcgattagtg caaaagaaat gggctttaaa gtaggtgtgc tggatcctgt
    21901 gagcgattgt ccagccgcac aagttgcaga ttggcacatt gaaagtgtct atgatgacac
    21961 ctttgcgctg aaagagcttg ccagaagaac agatgtcatt acctatgaat tcgaaaacgt
    22021 cagtgtagag gcgttaaatg cgattttacc catgtcattt attcctcaag ggacagactt
    22081 gcttgcgatt acgcaagacc gcctgttaga aaaatctttt ttggaaacga ataacatcgt
    22141 gattgctcct tatgcaacga tcgtcagtcc gacggatatc caagatgcga ttgacgggat
    22201 cggctatcct tgtgttttga aaaccactcg aggcggctat gatggcaagg ggcagtatgt
    22261 tttgaaaagt cgggcggatc tagctcctgc catggacctt ttaagagaag gaacctgtgt
    22321 tttagaagca tggatcccgt ttgaaaaaga gatttcgatc atggtggcag gaaatggtca
    22381 aggagatttc acgacttttc cggtcgtgga aaacatccac cacaacaata ttcttcatga
    22441 aacgattgct ccagccgcga ttgatcagga tgtgatcgag gaggctgagc gtattgcccg
    22501 tgtgattgca gaagcagtga gcctttcagg tgttttaggg gtagaaatgt ttttaacaaa
    22561 aacaggcggg ctatatgtga atgaattagc tcctcgtcct cacaattctg gacattattc
    22621 tattgaagct tgttctatga gtcagttcga tgcccatatt cgaggtattt gtggttggcc
    22681 attaggagaa aaagtacgtt tgataagcaa tgcagtaatg gtcaatgttt tgggagaaca
    22741 actgctggaa agctatcgct tgattgagaa taagccagac tggcaattcc atttctatgg
    22801 aaaaaaacaa gcaaaaaaag gtcgcaagat gggacatatc actatcttga cagaagacat
    22861 ccagcaaacg ctggaagaaa tcaaacaaac gaatatttgg gattagagga gaaaaaacat
    22921 gttagaacgt tatacacgcc ctgaaatggg gaatatctgg acggaagaga acaaataccg
    22981 tgcgtggctc gaagtcgaga ttttagcaga tgaagcttgg gcagaacttg gtgaaatccc
    23041 gcaagaagat gtgaaaaaaa ttcgtgagca tgcatcattt gatatcgatc ggatcttgga
    23101 aatcgaaaaa ttaacacgcc atgatgtcgt tgcgtttaca cgagcggttt ctgaaacatt
    23161 gggagaagaa agaaaatggg tccattatgg tctaacaagt acggatgtcg tagatactgc
    23221 ttatggctat ctcatcaagc aagcaaatga tattttacgg gaagacttga aacgttttac
    23281 ggaaatcatt ggcgaaaaag caaaagaaca caaatataca gtgatgatgg gtcggacaca
    23341 cggtgtccat gctgaaccaa ctacttttgg attgaaactt gccacatggt attcagaaat
    23401 gaaacggaac atcgaacgat ttgaacatgc ggcaaaagga gtagaagcag gaaaaatctc
    23461 aggagcagtg ggaacgttcg caaatatccc gccatttatt gaagagtatg tatgtaaaca
    23521 attggggatc cgtccacaag aaatctctac tcaagttctc cctcgggatc tacatgctga
    23581 atatttctca gcgatggcgc ttattgctac aagtattgaa cgttttgcaa cagagatacg
    23641 cggattgcaa aaatccgaaa cacgtgaagt agaagaattt tttgcgaaag gtcaaaaagg
    23701 ttcttctgct atgccgcaca aaaggaatcc gatcggttca gaaaatatgg ctggtctagc
    23761 cagagtggtg cgcggacaca tggtcactgc ctatgaaaat gtcacattat ggcatgaaag
    23821 agatatttct cattcttcag cagaacgaat catcttgcct gataccacga ttttattgaa
    23881 ttacatgtta aatcgttttg gcaatatcgt taaaaatcta acggtctttc ctgaaaacat
    23941 gaagcggaat atgtctgcaa catttggttt gatttatagc cagcgcgtta tgctgaaatt
    24001 gatcgataag ggaatgacaa gagaagaagc ttatgatctt gttcagccaa aaactgcgta
    24061 cgcttgggac aaccaagtgc agttccgccc gctgttagaa gaagatccaa ccatcacatc
    24121 ggtattatct aaagaagaaa tagacgatgc ctttgattat catcatcatt tgaaaaacgt
    24181 tgacgtgata ttcaaacgag taggtttgga ataaagaaga gtgagttgca aaattcaatt
    24241 aaaatagaat agcaaaaata atcgagtaga ggggaaagcc aactgacctt ccgcccctct
    24301 cacaccaccg tacgtacgga cccgtatacg gcggttcaat aagttgagtg tacgaactgg
    24361 tacttcaagg agatgtcctc atatccttgg cgggccagtt ctttgtctgt taatgatcga
    24421 tgaagaatat gacttttgga gactgaccaa ataccttttc ttgtatttga ccattcatac
    24481 gctttcgctt tatcgatccc taaacgaatc agattttttc ttttggttct tggattcttc
    24541 cattgtttcc aaatatattg tctgattctt cgcttcaacc aaccgtttaa ctccctcatg
    24601 aattctttca tctcaccaat tccatagtag ttgatccaac cagtcattag ttgcttgatt
    24661 tcttttaaaa taagttggat acttcttcca cggtttcttt tagtgagttg tttgagcttg
    24721 cttttcacac gctgttttgc ttttgcgtga gggcgaattt taataccttt ctttgttggc
    24781 agaatgcaga atccaagaaa ctttcgtttc aatggacttc ctaccgcact cttttctcga
    24841 tttaccgtca actttagttg ttcttcgaga aattgaatgg atttcttcat cacacgctgt
    24901 cctgctcgtt tgcttctaac atagatattg cagtcatcgg cgtatcgaac aaatttatgt
    24961 cctagatttt ctagcacttg atcaaattcg ttcaggtaga tgttacttaa caggggagag
    25021 agattgcctc cttggggcgt tccttcttca gttgttgtga tgagtccatt ttccattaca
    25081 ccactcatta agtattgacg gatcagtttt aggacttgtt tgtcctttac tttccgctca
    25141 atgaaataca tcagcttatc gtgatttacg gtgtcaaagt aggctttcat atcaatgtcc
    25201 accacatatc ggtaaccttg ttcataataa gattttgctt tcttcactgc gtcatgtgcg
    25261 ctgcgatttg ggcgaaaccc ataactatta tctgagaatt ctggttcaaa tagcggttgt
    25321 aacacttgat tgattgcctg ttgaagcata cgatcaataa ccgtgggaat tcctagtttt
    25381 cttacaccgc cgtttggttt cggtatttct actcgcaaaa caggctgagg tttatagttc
    25441 ccttggcgta aattggatag taattcctcg cggtgctctt tcaagtaagg aagcagttga
    25501 tcgacggtca tcccatctgc accagccgcc cctttatttc tgactacttg aagatacgct
    25561 tgattgagat tattccgatc tagaattctc ccaaacagat tttctacacc atcttgtttc
    25621 ctctgttcac cgcaagaagt gctgcgcact tcatcatacc cttcgtgttc cacactagct
    25681 ctttgatgat agccaagttt tcttgttttc tgcggtcgtc gcatcttctc acacctccta
    25741 aattattcaa gattcttatt gttcagtcct tcgtaacggt cagtgtcgtt actactatga
    25801 cctcggctga cttctcatga ttcaccatca tgtcgccatg atcgttgtgc tggtttgttt
    25861 tcattcaacg cccacaacac cctcatgaga tctcccccgg taagagtgaa aactttcctc
    25921 ccatgtaact gctagattta ctgtataggt ttcgggcagt attggacttt gtcttgtgat
    25981 gaagacttat ccgacctaat tcagccttgt atctagtttc tgttcgtcag ttcaggagtt
    26041 tgcgtccgac ttccttcagc cacaacctca cgattgccgc cttgtctttc gctaacagtt
    26101 cctactgcca agcctgtagt ggactttcac caccaagttt tcacccatgc agggcgcaca
    26161 ccaaaaaaga agcagatccg ttagcggttc tgcttctttt agtttattat attttcttat
    26221 caataatagg aacctgattt taaaagcggc tacctcttta ccgtgcctct ttacatacaa
    26281 aaaatagagg aattaagcgt aaatggcttg gctattataa ctaaaatgct ggttatggag
    26341 atgttgcagc aagttttcga gaaaagcgta ttccatctct tgtccattga ataagatctg
    26401 gatacgataa tgatttttga aacgcttctg ttcatgaatc tgactgattg aaagttcgcc
    26461 tttgtgttct gtctgataaa gaaaagtcct tttacggcat tcagcacagc gcttggttgc
    26521 tcggcggatt tttcggaatg tataaaaact agtatcttta ttgcataaat aaacgtcttt
    26581 gatcgacagc aaatcattat atagacagga acgttcttca gctgttaatt ctgataaaaa
    26641 aagctgacct tgttttattg catcttccat cggcaagtgc ctcctcgaac ccattatcca
    26701 aatttttagt taattctaat ataccatcat taagtataaa tgtaaacgct tgttgatggt
    26761 ataagatttt cgtttctgat aaaacacgaa cattaaaaga atctaatgcc ttaaatgtac
    26821 atatttttgt tgatttataa aaagatgatt gctaaaattt aaagtgaaaa aacgaacaaa
    26881 aaacgatgta tttgctttta atgtaaataa aaaggagaga cgtacatgga gaagaaagaa
    26941 cttttgtatg aaggaaaagc caaaaaaata tatcttactt ctgatgagaa cttgatttgg
    27001 atagaatatt tagatcaagc aactgcgttg aatggcgcga ggaaagacca gataagtgga
    27061 aaaggagaat tgaataatca aatcacaagt gcaattttcc gttatctgac tcaaagagga
    27121 ataaaaaatc attttattga acaattgtct aaaaccgaac aattagcaaa aaaagtacaa
    27181 attatccctc tggaagtggt tatccgaaat attgcagcag gaagtttctc aaaacgtcta
    27241 ggtgttcccg aaggtaaaga attcatcaaa ccaatcattg aattctacta taaggatgac
    27301 cagttggatg atccatttat caatgaagag catatctatt tcttacaact tgcaaagccg
    27361 gaagaaatca gtgagctgaa agcccaagcg ttggctatta atgaaatttt gaccgaatta
    27421 tttgctaagg tcggtttggt tttagtagat ttcaagctag aatttggccg gtcgaatgga
    27481 caaattttgc ttgcggatga agtaacaccg gatacttgcc gattatggga tgaacgtacg
    27541 aatgaacata tggacaaaga cgtttaccgc agagatctag gtgatttgat cccagtctat
    27601 caagaagtat ataaccgtct atcggaacta actgaagaaa aggagcgagt atgatgtatt
    27661 tcgtaaaagt atatgtaacc tataaagatt cagtgttaga tcctcaaggg gaggcagtaa
    27721 aaaaagcagt ccatcgtatg ggatatgaaa caatcgaaga tatccgaata ggaaaatact
    27781 ttgagataca acttgctgat gcagaagaac caatcgatac agtgattgaa acgatttgtg
    27841 acaagctgct tgcaaatgta aatatggaaa cataccgata tgaaatcaaa aaaatggagg
    27901 aagtataaca tgaaatttgc ggtcatcgtt tttccaggtt caaattgtga cgcagatatg
    27961 ttatgggcag ttcgcgagat catgggcgct gatgccgaat ttgtacggca tgatgagtcc
    28021 tctttagaag gatttgatgg ggttttactg ccgggaggat tctcctatgg tgactatttg
    28081 agatgcggtg cgattgctcg gttttctaca atcatggaag aagtgattcg ttttgctgaa
    28141 gaagggaaac cagtattcgg tacatgcaat ggattccaga tattgacaga agcaggactt
    28201 ttgccaggtg tactgagacg aaatgagtct ttgcatttta tttgcaaaac tgtaccattg
    28261 aaagtcaacc ccaagacggc ctttacttca gagtatgaag ccgacgaaat aatctatctt
    28321 ccagttgctc atggggaagg aaattatttc tgtgacgaag aaacacttca agaactaaaa
    28381 aaaaataatc agattgcctt tacttataat gacaacatca acggcagcgt ggaaaacatt
    28441 gcagggatta cgaacaaagc agggaatgtg ttaggaatga tgcctcatcc agaacgtgca
    28501 gtagaagact tgctaggatc agaagatggg aaacggttct ttgcttccat tttaaaaaac
    28561 ttcggaaagg tgaccgtata gatgaaaaca ttgaaagaac cgacagctga agagatcaag
    28621 aaaaaaagaa tctatgccga atggggattg actgatgaag aatatcgaat gatcgaagaa
    28681 gatatcttag gaagaatgcc taattatacg gaaactggac tgttttctgt tatgtggagc
    28741 gaacattgtt cctataaaaa ttctaaaccg gttctacgca aatttcctac tagtggacct
    28801 catgtgttgc aaggccctgg agaaggcgca ggcatcgtcg acatcggtga tggactagca
    28861 gttgtcttca aagcagaaag tcacaatcat ccttcagccg tggagcctta tgaaggagct
    28921 gcgacaggag ttggcggaat catcagagat attttcagca tgggggctcg tccaattgcg
    28981 ttgctagatt cattgaggtt cggcgaatta gataatccaa gaacgaaata tttactagaa
    29041 gaagtagttg caggtatcgg cggatacggc aattgtatcg gcataccgac tgtaggcggc
    29101 gaaattgcat ttgatccttg ttatgaagga aacccattag tcaatgcaat gtgcgtaggt
    29161 ttgattgaac acaaacatat ccagaaaggg caagccgctg gcgtcggtaa ttcgatcatg
    29221 tatgtaggtg caaaaacagg tcgcgacggt atccacggag caacttttgc ctcagaagaa
    29281 tttaatcaag aagaagaaca gcaacgttct gctgtacaag taggcgatcc ttttatggaa
    29341 aagctgctgc ttgaagcgtg tttggaatta atcttgcatc attcggattc tctaataggt
    29401 atacaggata tgggagcagc aggacttgtt tcatctagtg cggaaatggc ttcaaaagct
    29461 ggctcaggac ttatattgac attagatgaa gtcccacaaa gagaaactgg gatgacacct
    29521 tatgaaatga tgttatcgga atcacaagaa cggatgttga tttgtgttaa atcaggagag
    29581 gaagaaaaaa tccaagaact atttcagaag tatgatctag atgcagtcac tatcggtaaa
    29641 gtaacagacg acgggcaata tcggctatat catcaaggag aagaagtagc aaatctgcca
    29701 gtcgatgcat tagctgaaga tgcaccagtt tatcataaag aaatgaaaga accagctcga
    29761 atcgtagaat ttcagcagtt agctccttat cagccagtta tcgaagaacc tggacaagta
    29821 ttgcttgatc tgctgcagca accgacgatt gcttcaaaac gttcaatcta cgaaacttat
    29881 gattcacaag tacaaaccaa tacagttgtc cgtccaggaa gcgatgctgc tgtgatgagg
    29941 gttagaggga cgaataaagc gttagctatg accacagact gcaacgcgcg ctatctgtat
    30001 ttggatccaa aaatcggagg acaaatagca gtggcagaag ctgctagaaa tattattgct
    30061 agcggtggta agcccttggc gatcaccgac tgcctgaact atggttctcc tgataaacca
    30121 gaagtttttt gggaattatc gacttcagct gacggaattg ctgctgcgtg tgaaacgtta
    30181 ggaactcctg ttatttcagg aaatgtctct ttatataatg aaacggatgg tcaagcaatc
    30241 tatccaacac caatgattgg tatggtcgga ttgattgagg atcataaaca tatcactact
    30301 caggaattca aaaaatcagg ggatctaatc tatatattag gtaagacgtt tgcagatttt
    30361 gatggcagtg aattacaaaa gatgcagctt ggaagaatcg aaggtgtgat ccgaaacttt
    30421 gatctatcca ttgaaaagag aaaccaagag ttagtattga cagccatcca aaacggattg
    30481 attgaaagtg ctcatgactg ttcagaaggt ggcttggcaa ttgcactggc agaatcagct
    30541 ttcaaacatc agctagggat atctgtacag tttgaattgt cctctgctca attatttgca
    30601 gaaactcaat caagatttgt gttgacagtc gcaccggaaa ataagacacg attcgaagaa
    30661 atgatgggag atgctgctgt tttagcaggt aaggtgacgg atgaagcgat aatcgaaatt
    30721 tcagcaactg acggtcagat caaaatagaa actgcagtag caagaaagtg ctgggaggat
    30781 gcaatcgtat gtcttatgaa gtgaagagtt taaatgaaga atgcgggatc ttcggtgttt
    30841 ggggtcatcc agacgccgct agtgtggcat acttcgggct ccatagtctt cagcatcgag
    30901 gacaagaagg tgcaggtatc gtgtccaatg atcgaggaaa gcttaagggg catcgagatt
    30961 tggggctgct ttctgaggta ttcaaagatc aaagaaaatt gcagcagtta acaggagaag
    31021 ctgcaatcgg acatgtacgt tatgcaacag caggcaatgg aagtgtggac aatattcagc
    31081 cttttctatt caaatttcat gatcagtcga tcggcttagc gcataatggt aacttgatca
    31141 atgctcgttc ccttagaaaa gagttagagg aaaatggggc gatcttccat tctaactccg
    31201 atacggagat attgatgcat ttgatccgac gaagtgaaga aacagatttt ttaaataaat
    31261 taaaaagtgc tttgaatgaa gtcaaaggtg gctttgccta tttattaatg acagaaacgg
    31321 caatgattgc cgctttggac ccaaatggtt ttcgtccatt agcaatcgga caaatgaaaa
    31381 acggagcata cgtgattgcc tcggaaactt gtgcattaga agttattggg gcacgtttta
    31441 taagagatgt ccagcctggt gagatagtga tcatcaatga cgaaggaatc cagattgatt
    31501 gctttacgaa ggacacgcag ctttctattt gttcgatgga atatatctat tttgccagac
    31561 cagattcaaa catcgcaggg atcaatgtgc atactgcacg gaaaaatatg ggacggaatt
    31621 tagcgaaaga atcgccagta aaagcagata tggtcgttgg cgtacctaat tcttctttgt
    31681 cagccgcaag cggttatgcg gaagctagtg gaatccctta tgaaatcgga ttagtaaaaa
    31741 atcaatacat tgcccgaaca tttatccagc caacgcctga gctaagagag caaggtgttc
    31801 gaatgaaatt atctgctgta cgaggagtag tggaaggtaa aaaggtgatt atggtcgatg
    31861 attcaattgt tcggggtacg acaagcagac ggatcgtcca tcttttgaaa gaagcagggg
    31921 caaaagaagt ccatgtgagg attgcttctc ctcctttgaa atatccatgt ttttacggga
    31981 ttgatattca aacgcgtaaa gaactcattg cggcaaatca cacgattgat gaaatcaaag
    32041 aatgtatcgg tgcagattct ttaggttttt taagtgaaga gggtctgatc gaatcgatcg
    32101 gtctggaaaa agatgctccg tattcaggat tgtgtatggc ttatttcaac ggagattatc
    32161 cgacgccgtt atatgactat gaagaaaaat atcaggaatc actaaaagaa aaagtatcgt
    32221 tcttttaaaa gcagaccaag aagggagtat atgaattcaa tggcaaatgc atacgcaaaa
    32281 gctggcgtag atgtcgaagc tggatatgaa gtagtagaac ggatcaagaa gcatgtcaaa
    32341 aaaacggaac gtttaggtat gatgggcgct ataggaggat tcggcggttg ttttgattta
    32401 tcggtctttc aattaaaaga gccagtcctt gtctcgggga ccgatggcgt ggggacgaaa
    32461 ttagcagtgg caatcgaagc agacaaacac gatacaatcg ggatcgactg cgtagcgatg
    32521 tgtgtcaatg atatcttagc acaaggcgca gagccgttat atttcttaga ctacttagca
    32581 acggggaaaa atgatccgtt acgtttggaa aatgtagtaa aaggtgtagc agatggatgt
    32641 gttcaaggaa atatggcgct gattggcgga gaaacagctg aaatgcctgg tatgtactca
    32701 ggtaatgatt atgatctagc cggatttgct gtagggatag ctgaaaaatc tcaattattg
    32761 acaggagaaa cgatcaaccc aggagatgtg ttgcttggaa tagcatctag cgggattcat
    32821 tcaaatgggt actctcttgt tcgcaaaatt ttctttgagc agcagcagtt ttctttatca
    32881 tcaaaactgc cagaattgaa aaaaacactt ggcgaagaat tgcttgagcc aacgaaaatc
    32941 tatgtttctt ccttgcttcc gctgatcaaa gaaaagaaaa taaaaggagc tgcacatatc
    33001 actggtggag ggtttgtaga aaatatcccg cgaatgttac cagaatctat ggctgcacaa
    33061 atcaaacttg gctcatggcc gattcttcca atattcggct gtttacaaaa atatggtgaa
    33121 attcctgaga tggagatgta tgaaatcttc aatatgggca tcggtatggt cctggcagtc
    33181 gaagaatcga aagtaaaaga aatagtacac gaaattgagc aagctggcga aaaagtttat
    33241 gaaatcggga aagtgatcgc caaagaaaaa catcgtgtgg tgtttatagg agaagaacga
    33301 tgagaatcgc tgtttttgct tctggaaacg gaagcaactt tcaagcgcta gccgattatc
    33361 tatcgaaaaa aggattggaa tcttcgattg actggttgtt ttgtgatcag cctgaagcat
    33421 atgttttgaa acgtgcaact gcgttgagtg taccggcaga ttgtttttca cctaaagaat
    33481 ttgattcaaa aaaagagtat gaagaagcaa ttttgcataa attgaaagaa aaaaagatcg
    33541 atttgatcgt attagctgga tatatgcgaa tcattggacc ggtattgctg aaaaattatg
    33601 ataaaagaat catcaatatc catccgtctc ttttacctgc cttccctggt ttgcatggca
    33661 tacgtgatgc ctttgaagct ggagtaaaag aaacgggtgt cacaattcat tatatcgacc
    33721 aaggtgtaga tactggacca atcatccggc aggaaaaagt gagaattgaa caggaggaca
    33781 cgttcgattc tttagaagaa aaaatccata gagtagagca tcgaatctat ccagaagtga
    33841 ttagtgaaat tattgaaaat ggaggctatc tgaaatgaca agagcattga tcagtgtatc
    33901 agataaaact gggattgtag cattcgccca aggtttgatt gaacaaggag tagaaatcat
    33961 ttcaacagga ggaacaaagc atgcgttgga taaagctggg atcaaaacgc tttcgatcga
    34021 agaagtgaca gggtttcctg aaatgatgga tggccgtgtc aaaacacttc atcctaaaat
    34081 ccatggtggt cttttaggaa gacgcgatct ccctagccat atggaggcaa tggaaacgga
    34141 aaatatccaa ccaatcgact ttgtttgtgt caatttatat cctttcaaag aaacgattat
    34201 gaaaccagat gtcgaaatag cagaagctat tgaaaacatt gatatcggtg gtcctagtat
    34261 gctccgtagt gcagcaaaaa accatgaatt tgtcacctct gttgttgatc catctgacta
    34321 tgaagaagta ctttcagaat tacgtcagta tgggcatact tcactttctt tcagacaaaa
    34381 actagcggca aaagtctttc gtcatactgc ggcatatgat gcactgatcg ctcaatactt
    34441 aacggattgg gtggaagaaa aagaaccgga aaaattgaca cttacgtatg aacgaaaaca
    34501 aacgcttcgt tacggtgaaa atagccatca agccgctgcc ttttatcagt ccgctcttct
    34561 ggaaaaatat tcgatcgcag cagcaaaaca actccatggg aaagaacttt cttataataa
    34621 tatccgagat gcagatgctg cgctacggat catgaaggaa tatgacgagc caacggtagt
    34681 cgccttgaaa cacatgaatc cttgtggtat tgggacagca tctacgattt tagaagcgtg
    34741 ggaagcagcg tatgaagcag atcctgtttc aatctttggt gggatcatcg ttttgaatcg
    34801 agaagtagat ctgccaacag cagaacagat gcataagctg tttctagaaa tcatcattgc
    34861 cccttcttat acacaagaag ctttggaatt actgcaaaaa aagaaaaaca tccgattact
    34921 gacagtagac tttgcgcagg aagaaaatca aaatcgagaa gaaacggtct cagtcttagg
    34981 tggacttctt gtacaagatc aagatctggc aatagaaaat gaagaagagt ggaaagtcgt
    35041 gacaaaacgt aagccgactc cagcagaagc aaaagcatta gcgtttgctt ggagagctgt
    35101 caaacatgtg aaatctaatg cgatcgtact ggcaaacgaa cgtcagacag taggaatcgg
    35161 agccgggcag atgaatcgag tcggttcagt aaaaattgcg attgaacaag cgcaagagaa
    35221 aatggaaggt gcagttttag ctagcgatgc ttattttcca atggatgatt cggttgaata
    35281 tgcagccaaa catggtataa aagcaatcat tcagccagga ggaagcatca aagaccaaga
    35341 ttctattgat atggcgaata aatacgatct agcaatggtc tttactgatg ttcggcattt
    35401 tagacattag agaggagtcg gataaatgaa cattttggtg atcggtgcag gtggtcgtga
    35461 acatgcaata agtaaaaaac ttttagccag tccgaaggtg gatacggtgt attgtgcgcc
    35521 aggaaatccg gggatgacaa aagatggtat caattgtgtc gctatcagtg agcgagatca
    35581 ttcagcgtta atccattttg ttaagaaaga ggctattgat tggagtatcg ttggtcctga
    35641 agttcctttg ttaaatggga tcgtcgatga ttttatggcg gaaggattga aaatcttcgg
    35701 tccgacaaaa gcagcagctc tgatcgaagg ttcgaaaagt tttgctaaac aattaatgga
    35761 tacttatcaa atcccgacag ctaaatccag aagttttgaa tgttacgaaa aagcagcagc
    35821 gtatatcaaa gaaaatggtg cgccaatcgt agtgaaagcg gacggcttag cagctgggaa
    35881 aggtgtagtc gtggctacca cagtgaagga agcgctggat gcggcagaac aaatgttgaa
    35941 ccagcatcga tttggggata gtagcaaaaa aatcgtcgta gaagagtttt tggcaggaga
    36001 agaattctcc cttttggcgt ttgtccgtaa taccaaggtg tatccgatgg tcatttcgca
    36061 agatcataag cgggcatttg ataacgataa agggccaaat acaggcggaa tgggtgctta
    36121 ttcaccagta ccgcaaattt caaaaaagat gattgaaaaa gctgtggaag aagttttaaa
    36181 accagcggct ttgggaatga aagaactagg acgctctttc acgggtgttt tatatgcggg
    36241 tttgattgct acgaaggaag gaccaaaagt gatcgaattc aatgcgcgtt tcggtgatcc
    36301 tgaaacgcaa gtcgttcttt ctcggttgaa gagtgacttt gcgcaagtaa tcgatgattt
    36361 attagagaat cgtacagtag agttaaagtg gcagcaagaa ggatacaatg taggcgttgt
    36421 ggttgcagct gccggttacc ccgaagaata tgagacagga atggttctac cagattttct
    36481 ggaagaagag ctttctgttt actatgctgg agtttcctca aataacggca aactagttgg
    36541 agcaggagga cgtctttatt tagtagaagc atacggtgag acgatcaaag aagcacagaa
    36601 aaaaatttac accgcgttaa tggataaaac gacagatgga acattttatc gtacagatat
    36661 tggagaaaaa gctgccaata gcgaactgat cgtgaagtaa atcagctgct tccatttata
    36721 aaaaatacaa caaacataat cggaagcgcc gattttagtg aagccttttc ataaagagtg
    36781 tggtacactt ttgttgtgta tataaataag gaggagttca gatgaaaaaa attcaattag
    36841 gtacttctga tcagaaagca gctgcagtga tcttaggctg tatgcgtatc aacaatgcgg
    36901 aagatccagt aaaagtgatt gagacagctt atgaaaacgg cattgatttt tttgaccatg
    36961 cagatattta tggaaacggt gaatgtgaag aaatctttgc agatgctcta gcaaaaacat
    37021 caatcaaacg agaagatctt tttattcaaa caaaatgtgg aatcgttcca ggtgtgatgt
    37081 ttgatttttc taaaaaacat atcattgaat ctgtagaaaa aagtttgacc cgtctgaaaa
    37141 tggattatgt ggatgcttta cttcttcatc gtccagatac attggtagaa ccagaggaag
    37201 tagctgaagc gtttgatgaa ttggaacggt caggaaaagt tcgttatttt ggcgtcagca
    37261 atcaaaaacc aatgcaaatc gaattgctga aaaaatatgt tcgtcaacca ttagtagcta
    37321 atcagctgca atttggcttg aaacatactg gaatgatcga tcaagggatt catgtcaata
    37381 tgacagatga agcaagtatc gatcatgacg gtagtgtact tgattattcc cgattgcatg
    37441 atatgacgat ccaagcatgg tcaccatacc agtatggatt ttttgaaggt gtatttatcg
    37501 ggaacgaaaa attccctgaa ttaaaccaaa cattagaaga actagcagct aaatatcaaa
    37561 cgacaccaac tggcttggct tctgcttgga ttttacgcca tccagccaat atgcaagtga
    37621 tcgccggtac gatgaacgta gggcgaatca aggaaatcgc tcaagcttca gaaattaata
    37681 tgtctcggga agattggtac gaattgtacc gtgctgctgg aaacatttta ccttaaagat
    37741 tgtcataagc aggtcaaaag ggctataaat taaaaagaca gaataacttg aaagctgttt
    37801 tcagcttcga gatattctgt ctttttttat tgcaaatgga aagagtatca ttgtacggat
    37861 ttcgtttatt agttattttt gtttttaagg aaaagctgtg tccgatattc ttttggagaa
    37921 atcccttgtt ttttcttaaa taaataactg aaatagttag ggtcattata accaatttca
    37981 aaagcaatat ctgaaatacg atagtctgat tgctgcaata atttttttgc taattcgatt
    38041 ctttgttctg tcagataatc gatgaatgtt tggttaaacg attgagaaaa aatcgtactg
    38101 aaatgagagg gacttaatgc aacttgttga gcgacccaag ttaaggacat atctggatcg
    38161 gtaaaatttt ctttgataaa atccaatgca tggttcaaaa ttggctgata tttgttcctt
    38221 gaaggctgtg agggcagagc agttaagaaa gaaatgaaca tataaactgt cgaacggtaa
    38281 agcgagtcgt cggcgctgat tgctaagcgt tgactggtgg atgtgcaatg aaccatttct
    38341 tgcgggattt tcttttcttt caggcagaca tgctggagta gcttagtcaa gacaaataaa
    38401 cgatataatc gtgttcgagt tggtgtgcct tgtggtttcg tcaagtgttc gatgtactta
    38461 gatacttcgt ttttcgataa tgaagacaaa tcaagtgaga ggtcaaagta aaagacagaa
    38521 tcaactggaa gtttcgcttc ttgaatcaaa tcctcatagc tgataatttg ttctttaagg
    38581 gaactggcgg tttcaagtat catctgcgtg atctcaaaag atgcaggtaa ttcgctgatt
    38641 ctttctgcga caggaccaat ggcgacagaa aaattatttt tttgtccctt ttctaattca
    38701 tggaccaacg tttgggctac ctgataactg gtctcgatca cattttcttc aagagaatca
    38761 actattaaaa atttgatgaa tcgagaggaa acagcagaga agatcacttg ttgattctcc
    38821 ctaaataaaa acttcaaata atcactgaga tgagcgtaat cttcaaagtc tgtactgact
    38881 tggtttgctg ctaataatac ggtcattttt ttccctgcta aagagcgatt gaaagattca
    38941 gcaagtttca atgtttcact gatcgtaagt gagcctttga acaaaccgtt caagaaatga
    39001 ttttttttca attcgaaaac aagatcagaa gaagtgtgcg tttctttttg ctgcaaatct
    39061 aaagcagtta ctgctttttc tattgcttgt ttcaattcgc tacttttaat cggtttaagc
    39121 agataatcat ctgcctgtac ctggattgct cctttcatat aatcgaaatc gtcgaatcca
    39181 ctaataaata tgagacgagt ccaaggaagt agtttccttg cttcttttga aaaagtcaac
    39241 ccgtccatga aaggcatttg gatatcagtc agaatgatgt cgggctgtaa gtcgataatt
    39301 gaagacagtg ccatctcacc atctccagct tcgccgacat aagtgattgg ataataagaa
    39361 ccaaggacag ttatttgttc ccgcaagtta ttgcgaatga ggtattcgtc ttcgatgata
    39421 aaaactttat acatgtttgt ttcctccaat tgttttggga gatagaggga tcatcagtgt
    39481 gacagttgtt ccttctcggt atttgctgtc aatcgtgata ggtttttgat catttccgta
    39541 ataaagaagg agacgcttgt ttacgttgta aagtccgtag ccgatactga aatctgaatc
    39601 gatccctttg gctaactctt tacgtatttc tgccagtttt tctgcaggga tgccaatccc
    39661 gttgtctata actttgaatt ggatcatctc atcaattttg catgtggtaa tacgaataaa
    39721 tcctttgtga cggacgtact tcgttccatg gtatacagca ttttcaatca atggctgcaa
    39781 gatcattttt aaaatagaaa caggaaaaag tgtttctggt atatcgatct tatagtcaag
    39841 catatggccg tatcttattt ttaagatgac tagataatca ttgatatggc taatttcttt
    39901 ttcaagagga atccagtctt gtcctttgct taaagacgta cgaaaaaagc cggaaagtgc
    39961 atgggtcata gtcagagctt cttcaaagca gtcttgttcg atcaaagaaa taatggcatc
    40021 caaactgtta taaataaaat ggggagtaat ctgagcttgc aatacacgaa cttcactttg
    40081 tgctaaatgg tattgtttca aagcgttctc ccgtaaagac tggtttagat cttccgccat
    40141 tttattcatg ctagcggtaa gtgtttgtaa ttccagtgtt tccggcaggg ttaaacgaaa
    40201 gccaaggttc cctgaagaaa gttgttctga catctcgatc agctgattga tcggttcttg
    40261 gacctttctc tctaaaaagc gacgattctt tttcgcatag aaaaaaatgg tactaagaac
    40321 tccaagttcc actattgtta atagaatgag cgagcggaca agtgtcgtat tttttttgct
    40381 tgctaagtcg atctccacac gaacaaaatc ttgtaagata tctgacagca gttgagtgac
    40441 agaatctacc tgattgatga tctcttcatt ggtatccata aaatcttttg ccaagatatt
    40501 attgatcagc tcgttttgat aatcttccag tgtatcgatc gtacgtagcg atacatctaa
    40561 cgtactaatt tctttaagtg tatttgtatt atttttgatc tctcgaatat cattcctaag
    40621 ttcttctagg atattttcct cattgaactc atctacggtt acttggccag aaatcaagtc
    40681 ccacatactt tccaaaactt tttgatcaac cttcaaagca attgcatctg ctttttggat
    40741 atttgcgatc gtctgttgat aaatcaaaag ctgttgcgaa tataacagta tgctcagtag
    40801 caaagggata acagcaaata gaagcatggc tttgtttgct tgggcaaaaa tctgttttat
    40861 gcttaaattt tttgtcatga tacttctcca gtcaataatt tctggttggg atgttagcta
    40921 tattctgctg ggaaaagaca gtctcggaaa taaaaatatc tttaggtaat gtttttcctg
    40981 tttgaatatt tccaaaataa cgagtaacgg tattggctac ataccagccg acatcaggtt
    41041 tacactcgac tacacaattg acgattcctg agcgtagctt ctcgatcata tcttcttgtc
    41101 catcaatagt tacaatgatc aaatcttctc caggtttgat tgatgtttct tttatcgcag
    41161 ctaaagcacc gtgagtcatt tcatcactat ggctgtataa tacatcgatt tcggataaat
    41221 catttgtttc taaatatcgt ttcatctggt cttttccttt catccgaata aaatcaccga
    41281 caattcggtg aacaatagtc atcggaggtt tatggtcgat ggttccatct ttttttaggg
    41341 ttggtttacg attgattgat tccaaaaatc cttcggagcg tagcttggtc ggtgtggagt
    41401 tctctgaacc agcaagttct aggattctga tttcctgttt ctttgaattt gtgaagtgat
    41461 tgctgacaaa taaacccgcc cgatttcctt ctgctttgaa actggggcca atgtgggtga
    41521 cgaaaagctc gggatcattc gtttgaatat gtctgtcgac aagtatgaca gggatccctg
    41581 ctcgctttgc ttcttttaat acagagtccc acccggattc ttgcaaagga gtaaaaatga
    41641 tcatatccac tttataggca atgaacgtcc gtatatcttg gatttgccgt tcctgattca
    41701 tgtagccatt tcggtagaga acttggtaat cttctttttc aagcgcagtg ataattgatt
    41761 cagtatgctt tttccgccag ctactctccg ttcctgattg cgaaaaacca acgactagtg
    41821 ggtcaggtgc ttcctttgta ttaggtgtac accccatcat ttggtaagcg attacaacaa
    41881 gggctaaaaa aaataaaaca cgtttcactt taaatcactc catctggatt tgttagtact
    41941 atcttatcag ataaaaggga aaatcaaagt caaaaggaat caatcgaaaa aaatccaaga
    42001 aacttaaaaa aatccaagac aaaaaaagta cacctaaaaa atttaaagta aatcccataa
    42061 aaaaatcaat gttaacgctt tctttattag ctatactcgg tgtatcaatt gaaatggggg
    42121 ataaaaaatg aaaaacaaat ttagaaagat tgttgggact atcgctattt tgaccgcaag
    42181 cattctatta agtgcgtgtg gcaattcagg atctgcagat gatagtacgg ggtatgtagg
    42241 aatcgctatg ccgaccaaat cagcagaaag atggatcgct gatgggaaca acatggtctc
    42301 ggaattagaa aaactgggtt ataaaacaga tcttcaatat ggagaagata aagtagaaaa
    42361 tcaagtagca caaatagaaa atatgattac aaaaggggta gatacacttg tgattgcttc
    42421 tatcgatggt tcggctttaa ctgatgtgtt agctaaagca aaagaagcag atatcaaggt
    42481 gatcgcctat gatcgtttac tgatgaattc agaaaatgtc gattattacg cgacttttga
    42541 taattttgga gtaggtgtat cgcaagcagc ttatattgaa gagcacttag gattgaaaga
    42601 aggaaaagga ccattcacga ttgaattatt tggtggctcg cctgacgaca acaacgcact
    42661 aatcaattac aacggagtga tgtctgtttt acaaccatat atggacaacg gtcagttggt
    42721 cgtgccatct ggacagacga gtttcagtca aatcgctacg cttcgctggg atggttctac
    42781 ggcgcaagca aggatggata atctgttaag cgcaaattat actgaccaaa cattggatgc
    42841 tgttttgtcg ccatatgatc caataagttt aggaatcatt tcgtcattaa aaggcgtggg
    42901 gtatgggagt gaaagtaaac ctttacctgt gattactgga caagatgcga cagttgctgg
    42961 cgttaaatcg atcattgccg gggaacaaac acaaacgatc tttaaagaca cacgtatctt
    43021 agcaaaaaat acgattgaaa tgatcaaagc aatcagtgat ggagaagagg ttccggtcaa
    43081 tgatactgaa acttatgata atggggtgaa aactgtccct acgtatttag caaatacagt
    43141 atctgtcgat aaagataatt atcaagcaga gctgatcgac accgattatt ataaagaatc
    43201 cgatctgaaa aattaagagg aaccaaacaa ggaactaaag agatctaagt cagagagagg
    43261 ataagaatta tggcggattg tattttaaaa atggcagata tcaccaaaaa attttctgga
    43321 atccgagcgt tagattgcgt gaatctgatg attgaacgtg gggaaatcca tgcattgtgc
    43381 ggagaaaacg gagcgggaaa atcaacattg atgaatgtct tgagcggctt gtatccatat
    43441 ggctcctatg acggggaaat cttttatgat ggaaagctgt gtcaatttaa agatttgaaa
    43501 gatagtgaag aaaaaggcat cgtcatcatt catcaagaat tagcactaag tccttatctt
    43561 tcaataaaag agaatatttt tctcggaaat gaacaagcag aaagaggcgt gattgattgg
    43621 gaactgacag aaaagaaaac atatgaactg ctgaataaag tcggtttgtc tatcgacccg
    43681 aatcttctag tatcccagat tggcgtaggg caacagcaac tagttgaaat agctaaagca
    43741 ttatcaaaat ccgtccgtct gttgattttg gatgagccta ccgctgcatt gaatgaagaa
    43801 gaaagcgcga atttgctgag attgatccga gagttgaaag agcaaggtgt aacctccatc
    43861 attatttcac ataagctgaa tgaaatcgtg gatatcgcag atcgaatcac cattttacgg
    43921 gatggacaga cgattgagac actagaaaat gaaatgatca gcgaagagca tattattcgc
    43981 ggaatggtgg gcagagattt agttgatcgt tatcctgaaa gaaaaccgga tattggagaa
    44041 gtttatttta aagtagaaga ctggacggtc tatcaccctc ttgatcacga gcgaatcata
    44101 aacgaccaca tcaacttgca tttgaaaaaa ggagagattg taggaatagc tggactgatg
    44161 ggagcgggca gaactgaatt cgctatgagt ctatttggac attcttatgg aagcaagata
    44221 tccggacgta tattaaagga aggggcagag atatcagtta agaccgttcc ttcagccatt
    44281 gcaaacggac tcgcttatgt ctcggaggac cgaaaatctt taggactgaa tctgctgatg
    44341 gatattcggg aaaacgtgac gctgagcagt ttggataaaa taagtcaaaa aggagtatta
    44401 gataaagaaa aagaagtaac tgaggcagaa aatttccgga aaaagatgcg tataaaaaca
    44461 aactccatcc atcaaattgt cagtagtctt agtggtggga atcaacaaaa agtcgtttta
    44521 tccaagtggc tgatgacaca acccgatatt ctttttttgg atgagccaac ccgtgggata
    44581 gatgttgggg caaaatatga gatctacacg attatcgaag aaatggcagc aaatggcaaa
    44641 gctgtctgtc ttatctcttc tgaacttcct gaaatattag ggatgtgtga tcgaatctat
    44701 acgatgaacg aaggacgtat tacaggagaa gtctcgcgag aagatgcaga tcaggaagtc
    44761 ttgatgaaat taatgacgaa agaagaggtg ggttaagttg gaacaggcaa aaaatcttac
    44821 ggataaaaaa gagaaaaaac taaatttgaa aagtagagca gctgatcttt ttggtcgcta
    44881 cagcatggtg atcattttag cgggactact tattgcgttt caattgatga cggatggtat
    44941 tttctggcgt ccattgaata taactaacct tgttctgcaa aatagccata tattagtact
    45001 agctgcaggg atgttattag ttgtgctctt aggtcatgtg gatttgtcgg tagggtcagt
    45061 gatggcgttt gttggtgcaa ttgcgggcat gatgatggtc aatcgccaaa tgaacccgtg
    45121 gatgacagtt atcgcatgtc ttgcagtagg cgggctgatc ggcgcatggc aaggtttttg
    45181 ggtagcttat gcagggatac cggcgtttat cgtgacttta gcaggattgc tgatgtttcg
    45241 tggactgaca caagttgttc taggaggcca atctctagca ccttttccag ctgttttcca
    45301 aaaaatgtct acgggttatt taccagactt aagcgaagga agcagccttc acttcttgac
    45361 attgatttta ggaatgatca tcacgatcgt gttagttgtt ggtcaatggc gaacaagaaa
    45421 tcgtcggaaa aatcatttat ttgaagtgga atctccaaca gctttcttgg taaaggcggt
    45481 atttacagca gtcgttgtac taggaataac ttatatcttt gcctcttatc aagggtatcc
    45541 gattattttg atcattcttg gtttgatcgt tgcagcatat gggtttttga caaataaaac
    45601 agtagcaggt cgacagattt atgcgacggg cggaaatcga aaagcggctg aactatcagg
    45661 gatcaaaaca aagcgaatca cgttctgggt attcgtcaac atgggagtca tggcagcttt
    45721 agctggatta gttttagctg ctcgattgaa tgcggcaaca cctcaagcag gtacatcgat
    45781 ggaactggat gcaatggcgg cagtatattt tggtggtgct tcgacttccg gcggcattgg
    45841 aacaatcatg ggtgcgattg tcggtggctt ggtcatgggt gtattgaaca atggcatgtc
    45901 gattttaggc gtcggggtag actggcagca ggcaatcaaa ggattgatct tgcttttagc
    45961 cgttgtgcta gacttgtata ataagaaaaa acgaacaacg taggagaacg ccggttattc
    46021 agaaaaaaga ctgtgacaag acatttgtca cagtcttttt ttcgctaaaa gcgaacattc
    46081 attgtttcgt ttgtatagac taaaaataat atatgttttt ttaccattcg tataaattct
    46141 ctttttgctc ttgatttttt tgcttaattg agttaaatta catagggcgc taaaaaaagc
    46201 cttgattaaa ttaataatgt tcgtgttttg ctggatgtga acatcaggag gataatgtaa
    46261 tgaaagtatt tgattacgaa gatattcaat taattcctaa taaatgtatc gtaaatagcc
    46321 gttctgaatg tgatacaacg gtcacattag gtaaacatac attcaaaatg ccagtagtgc
    46381 ctgccaacat gcagacgatt attgatgaaa caatcgcaga attcttagcg gaaaatggtt
    46441 atttctatat catgcatcgg tttgatgaag cagctcgaat tccgtttatc aaaaaaatga
    46501 aaaagcgtgg attgattacc tcgatcagtg ttggcgtcaa gaaagaggaa tattccttta
    46561 tagagaagtt ggcagaagaa tcgctaaatc ctgattatat cactatcgac atcgcgcatg
    46621 gacatgctaa ctcagttatt gatatgattc agcatattaa aaaatatttg cctgaaactt
    46681 ttgtgattgc cggtaatgtt ggtacaccgg aagccgtccg tgaattggaa aatgcgggcg
    46741 cagatgcaac aaaagtcggg attggtccag gaaaagtatg tattacaaaa atcaagacag
    46801 gctttgggac tggaggctgg caactggcag ctcttagatg gtgtgcgaaa gcagctcgca
    46861 agccgatcat cgctgacggt gggatcagaa cacatggcga tattgcaaaa tctgtccgtt
    46921 ttggtgcgac aatggtcatg attggttcat tgtttgccgg tcacgaggaa tctcctggcg
    46981 aaacaaaagt cgaaaatgga atcgtgtata aagaatactt tggttctgct tcagaattcc
    47041 aaaaaggcga aaaacgaaat gttgaaggaa agaaaatctg gatccaacac aaaggatctt
    47101 tgaaagatac actagtggaa atgcaacaag accttcaatc atctatttct tatgctggag
    47161 gaagagatct ggaagccatt cgaaaagttg actatgtcat cgtgaaaaat tcgattttta
    47221 atggagacac aatctaaaaa ataaataaaa tattaggatg ttgtgaaaaa gttgtcctgc
    47281 attaagtaat aagaacagcc aaacaaaaat agttctttat atgttttgtt tggctggaat
    47341 tattatcgca gatacaagct tttgaacatc attattcaga ataagggact gtgataagat
    47401 ttttgtcaca gtcccttatg ttttgcaaaa aaagtttttc ttttttctcg taaattcggt
    47461 aaaatcaaaa gaaaaaatag acaatagaaa agagaagctt atgtgggaaa aagtagagaa
    47521 aaaacaagga ccgatttatc gtcaaattat ggaacagatt atgagagaaa tcgaaaacgg
    47581 aaggatcaat cctggaagtc aacttgaatc agaacgaaaa ctagggcaac tttttggtgt
    47641 gaatcgttcc accgttgtcc atgcattgga agagcttagg gagcttgggg tactaacgag
    47701 caaacgtggc agcggatggt ttgttaatca gactgaatgg gggaaattcg ctgttccaag
    47761 aatcgattgg cggcaaatga tctctcctcg ttatgagcag acggactggt atgagcaaaa
    47821 aataagagaa gcaaagcaga tccaaaaaac atcgtttctt gatttatacg ctagcgagat
    47881 gccagatgag cttttgccga attttgagtt tccttcttat tctcttgaag aaatcttagc
    47941 ggaagaaaaa gaaatggatc ttttaggcta tactccgtta cgtaacaaaa tcaaacggta
    48001 tttggaaagt aaatttgaat tggcattttc ccccaaccag cttcttgtga ctggtggcgg
    48061 tcagcaagca atctttttga ttttacaaac gattctttca gctggagagg ggatagctgt
    48121 agagtcacct tctttttttt accgattacc tcttttcaaa gcttcaggaa cgcgtttatt
    48181 tgggataccg atggatgaag aagggatcga cttagaaaaa ctgaaagaat cgatccataa
    48241 aaataaattg aaagcagtgc ttatcaaccc gaattttcaa aaccctacag gaaaagtgat
    48301 gagtcaaaaa cgacgagaaa agctagtaga attgtgtcga cagtatcggc ttccaattat
    48361 tgaagacgat gtatttacgg atctttcatt tctaaaccaa gaagaagtcc ttcctatacg
    48421 aacgattgat ccggataatg tgttatacgt cggttcgtta tctagggttt taggaaaaac
    48481 aacgaaaatc ggttgggtga taggacctga gacttttatc tcgcaactag ctcaagcgca
    48541 agaaatgatg gagttttcga tgaatatcct tacacaaatc acagtggcta atgtatttaa
    48601 tgaagcaatt gatttgaaaa tgcaagatgt aagaaaaaag ttgaaagaaa aaagccgact
    48661 gataagcgct tggggagatt cacaatcgtt tttcaagctt cattcaattt taggtggtta
    48721 ctatgcctgg attacttggg atgggaaaaa actagacccc gaactagcag aaaaagtagt
    48781 agatatgggt cttggaattg caccaagtct actttttggg caagatataa atggaatcag
    48841 aatcaattac agtaggctgg atgaaaacca aataccgttg ttttattcaa agatgaaaat
    48901 tctagaaaag tggttaacag aataatttca caaagtaaat agattaaaga atataacagc
    48961 ttggatttaa atttcaagct gtttcttttt tttcggaaaa agaatacgat ataaagaaac
    49021 taagaaaaaa ccattatttg tacgtccgtt cacgatgtgt aaataaaata aatgtttgca
    49081 acaaaactgt ataacaccaa cgtttttaaa tagaaacaga tggttgtaag tttgattaga
    49141 aaatagaaaa aatgcagatg aaatataaaa cgctttcctt attgtgattt tattcactaa
    49201 tgctgttaat atgcggattg gcataatttc ctttcatcgt gaaaatttgt gcttttagct
    49261 tgtatttctc ataaatccat gataatttat taatgaagac ggttaaatag tgatacagtt
    49321 ttattcactg tttcaatcgc agaatgaaga gattttctta tagatgagag aggaatgtgt
    49381 gacaaatggc aaacaaaaaa gcaccgatcg acttccaagc actgctagat gaagtcaatg
    49441 cagatttccc agtatatcaa gcacttgatc aagatggaaa cgtagttaac aaagatttag
    49501 tacctgattt atccgatgat gaactcgttg aattaatgac tcatatggta tggtctcgtg
    49561 tattagacca acgttcaaca gcgctgaacc gccaaggacg cctaggcttt tttgcaccaa
    49621 ctgctggaca agaggcaagt cagctggcta gtgcttacgc atttgataaa gaagatgttc
    49681 ttcttccagg ttatcgggat gtacctcaac tagtaaaaca tggtttacct ttatctcaag
    49741 cttttttatg gtctcgagga catgctgcag gtaattctta tccggaagaa ttgaaagctc
    49801 taccaccaca aattatcatc ggtgcacaat atgtacaagc agccggtgtt gcattaggtt
    49861 tgaagaaacg aaacaagaaa aatgtcgtct tcacttatac tggtgatggc ggttcatcac
    49921 aaggtgattt ttacgaagca atcaatttcg ctggcgctta ccatgcaaat gccgtatttt
    49981 atatccaaaa caacgggtat gcgatctcta cacctcgtga aaaacaaact gcagcaaaaa
    50041 cacttgcaca aaaagctgtc gcagctggga ttcctggtat tcaagtcgat ggaatggatc
    50101 cgcttgcagt atatactgta tctaaaatgg cacgggaatg ggcgatcagt ggaaatggac
    50161 cagtcctaat cgaaacactg acttatcgtt atggaccaca tacactatct ggtgacgatc
    50221 caacccgcta ccgtacaaaa gacacagatg acgattggca gaaaaaagat ccattgatcc
    50281 gcttccgtaa atatttgacg gaaaaaggac tttggtctga agaaaaagaa gaacaagtca
    50341 tcgaagcaac taaagaagaa atcaaagcag ctattgctga agccgacaaa gtaccaaaac
    50401 aaaaggtttc agatttcttg aaaaacatgt tcgaagtatc tccacaatca atcaaagaac
    50461 aaattgcaat ttatgaagcg aaggagtcga aataatcatg gcacaaaaaa caatgatcca
    50521 agcaatcaca gatgccttag cacttgaact agaaaatgac gagaatgtcg ttgtttttgg
    50581 tgaagatgtt gggaaaaacg gaggagtttt ccgggcaact gaaggattgc aggaaaagtt
    50641 cggagaagac cgagtattcg atactccttt agctgaatct ggaatcgcag gattgagttt
    50701 cggtcttgcg ttagaaggat ttcgtccagt tcctgaaatc caattctttg gttttatttt
    50761 cgaagcaatg gacgaagtag tagctcaaat ggctcgtaca agatatcgaa tgagcggcac
    50821 tagaaatcta cccatcacaa ttcgttcgcc atttggtggc ggtgttcata caccagaatt
    50881 gcattcggat aatttagaag gtttgatcgc tcagtctcct ggtattcgag tagtgattcc
    50941 ttccaaccct tatgatgcaa aaggactatt gatttcttct attagaagta acgatccggt
    51001 tgttttccta gaacacatga aactatatcg ctcattccga gaagaagtgc cggatgaagc
    51061 ttacgaagtt cctttggata aagcagcagt tactcgtgag ggaacagatg tatctattat
    51121 cacatacgga gcaatggtgc gtgaagcaat caaagcagca gacaatcttg caaaagaaaa
    51181 tatatctgtt gaaatcattg atcttcgtac agttgcgcca ttagatgtag aaacgatcat
    51241 tcaatccgtg gaaaaaactg gtcgcgtagt tgttgtccaa gaagcacaac gacaagcggg
    51301 cgttgccgcg caagtagttt ctgagatctc agaacgcgct atcctttcat tagaagcccc
    51361 aatcggacga gtttctgcac ctgatacagt cttcccattt ggacaagcag aaaatgtctg
    51421 gttgccaaat gcaaaagata tcgaagacaa agtaaaagaa atcgcggaat tttaagaaaa
    51481 gaagggacga aacaaagtca tggcttatca atttaaattg ccggatatcg gtgaaggaat
    51541 cgcagaaggt gaaatcgtca aatggttcgt caaaccagga gatacgatca atgaagatga
    51601 tacattacta gaagttcaaa atgacaaatc agtagaagaa atcccgtcac ctgttacagg
    51661 aacggttaaa aatgtgattg ttccagaagg taccgtagca aatgttgggg atgtattagt
    51721 agaaatcgat gcaccaggac acgaagacaa tgaaggggac agtggtgtag ccgcagaatc
    51781 ccaaactcca gctaaaccgg ctgctgaacc cactgttgat acagaatcag ctggatcgtc
    51841 aagcgaagga gtcttccaat ttaagttacc ggatatcggt gaaggaatcg cagaaggtga
    51901 aatcgtcaaa tggttcgtca aaccaggaga tacgatcaat gaagatgata cattactaga
    51961 agttcaaaat gacaaatcag tagaagaaat tccgtcacct gtcacaggga cagttaaaaa
    52021 cgtgattgtt ccagaaggca ctgtagcaaa tgttggggat gtattagtag aaatcgatgc
    52081 tcctggacac aatagtgcac cgtcaactag tgcgccatca gctgaagcac caaaagaaaa
    52141 agtggaaaca tcaggttcag caagtgtcgt tgaagctgcc gatccaaata aacgtgtatt
    52201 ggctatgcca tctgttcgtc aatttgcccg tgaaaaagat gtagatatct cacaagtaac
    52261 tgcaactgga aaaggtggca gagtaacaaa agaggacatc gaaaacttct tggcaggtgg
    52321 tccaagcagt gcaccagcga aatcagaagc gccagaagcg gcagcaccga aagaagcagc
    52381 tcctgcagca gaaagcaaac cagctgcacc agcaaaacca ttcaagtcca acttaggaga
    52441 cttggaagaa cgtgtagcaa tgacgccaac acgtaaagct atcgctaaag caatggtcaa
    52501 cagtaagcat acagctccac acgtgacatt gcatgatgaa gtagaagtgt ctaaactatg
    52561 ggataatcgg aaacgattta aagaagttgc tgctgcaaat ggtacgaaac ttactttctt
    52621 gccatatgtc gtgaaagctt taacagcgac tgttaagaaa tacccagtat tgaatgcatc
    52681 tatcgacgat gcaaaccaag aaatcgttta taaacattac tacaatatcg gtattgcaac
    52741 tgatacggat cacggactat atgtaccaaa tgtgaaagat gcagaccgca aaggaatgtt
    52801 tgctattgca gacgaaatca atgagaaagc aaaattagct catgacggca aactatctgc
    52861 agaagatatg cgcaatggaa caattacgat cagcaatatc ggatctgtag gtggcggttg
    52921 gtttacacca gtcatcaact atccagaagt agctatttta ggtgtaggaa cgattgcaca
    52981 acaaccaatc gtaaatgctg aaggcgaaat cgttgtcggt cgtgtgatga aactgtcatt
    53041 aagtttcgat caccgtatcg tagatggagc aactgcgcaa caagcaatga ataatatcaa
    53101 acgtctttta gctgatccag agctattaat gatggaagga tgataaacaa atggtagttg
    53161 gagattttgc tgtagaatta gatacagttg taattggtgc gggacctggt ggctatgtag
    53221 ctgccatccg cgctgctgaa atgggacaaa aagtagcaat cattgaaaga gagtatattg
    53281 gcggtgtttg tttgaatgtc ggctgtattc cttcaaaagc actgatagct gcaggacacc
    53341 attatcaaga gtcactagat tctgaaatgt ttggagtaac tagtgaaaac gtcaaactag
    53401 attttgcaaa aacacaagaa tggaaagaaa acaaagttgt ccatacgttg acttctggtg
    53461 ttggtttcct attaaaaaaa cataaggttg aaacaatcga aggagaagcg ttcttcgtag
    53521 atgatcacac actacgcgtc attcatccag attcagctca aacttattcg ttcaataacg
    53581 caatcatcgc aacaggttcc cgtccaatcg agattccagg atttaaattc ggaggacgtg
    53641 tgttagattc tactggcgga ttagcattga aagaagtacc taagaaattt gtgatcatcg
    53701 gtggcggtgt gattggtgcc gaattgggcg gagcgtacgc aaacttagga gcagaagtaa
    53761 cgattcttga aggctcacca caaattttac caacttacga aaaagatcta gtaaaattag
    53821 tagaagatga tttcaagaaa aaaggcgtaa cagtcgtaac gaatgcaatg gcgaaagaag
    53881 cagtcgataa cggtgacagc gtgacagtga aatatgcagt ggacgggaaa gaagaatccg
    53941 ttactgctga ttatgtgatg gtcactgtag gtcgtcgtcc gaatacagat gatatgggct
    54001 tagaacaagc gggtgtcgaa gtaggagaac gaggattgat cacggtggat aaacaaggac
    54061 gtacgaacgt acctaacatc tatgccatcg gtgatatcgt tccaggggcg gcattagcac
    54121 acaaagccag ttatgaagca aaaatcgctg ctgaagcaat ctctggcaaa aaagtagctg
    54181 tagattataa agcaatgccg gcagtagcct tcactgatcc tgaattggct tctgtaggta
    54241 tgacgatcaa agaagcaaaa gatgctggta tcgaagcaaa agcatataaa ttcccatttt
    54301 cagggaacgg tcgggcatta tcgcttggta aaacagaagg attcatccgt ctagttacga
    54361 cgatcgaaga taacgtgctt attggcgcgc aaatcggtgg agtcggcgca agtgatatgg
    54421 tctctgaatt agctttagca atcgaatcag gaatgaatgc tgaagatatc gccttgacga
    54481 ttcatcctca tccatctctt ggcgaaatcg tcatggatgc ttcggaatta gcattaggtt
    54541 taccaatcca tatttgattt gaataataca ggcgaaacgc aactgaa
//
LOCUS       DAMEEU010000009        52266 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.009, whole genome shotgun sequence.
ACCESSION   DAMEEU010000009 DAMEEU010000000
VERSION     DAMEEU010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 52266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.009"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            344..682
                     /locus_tag="PB779_000565"
     CDS             344..682
                     /locus_tag="PB779_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738110.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            776..1006
                     /locus_tag="PB779_000566"
     CDS             776..1006
                     /locus_tag="PB779_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738111.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            1406..1777
                     /locus_tag="PB779_000567"
     CDS             1406..1777
                     /locus_tag="PB779_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDE0738112.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(2051..2743)
                     /locus_tag="PB779_000568"
     CDS             complement(2051..2743)
                     /locus_tag="PB779_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDE0738113.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(2746..3531)
                     /locus_tag="PB779_000569"
     CDS             complement(2746..3531)
                     /locus_tag="PB779_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDE0738114.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            3768..5168
                     /gene="lacG"
                     /locus_tag="PB779_000570"
     CDS             3768..5168
                     /gene="lacG"
                     /locus_tag="PB779_000570"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HDE0738115.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            5193..5510
                     /locus_tag="PB779_000571"
     CDS             5193..5510
                     /locus_tag="PB779_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDE0738116.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            5523..7196
                     /locus_tag="PB779_000572"
     CDS             5523..7196
                     /locus_tag="PB779_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HDE0738117.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            7210..8841
                     /locus_tag="PB779_000573"
     CDS             7210..8841
                     /locus_tag="PB779_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HDE0738118.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            complement(9332..10897)
                     /gene="guaA"
                     /locus_tag="PB779_000574"
     CDS             complement(9332..10897)
                     /gene="guaA"
                     /locus_tag="PB779_000574"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDE0738119.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVNARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(10956..11879)
                     /locus_tag="PB779_000575"
     CDS             complement(10956..11879)
                     /locus_tag="PB779_000575"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HDE0738120.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            12075..12680
                     /locus_tag="PB779_000576"
     CDS             12075..12680
                     /locus_tag="PB779_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDE0738121.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            12988..14004
                     /locus_tag="PB779_000577"
     CDS             12988..14004
                     /locus_tag="PB779_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDE0738122.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            14145..15446
                     /locus_tag="PB779_000578"
     CDS             14145..15446
                     /locus_tag="PB779_000578"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HDE0738123.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            15492..16154
                     /gene="deoC"
                     /locus_tag="PB779_000579"
     CDS             15492..16154
                     /gene="deoC"
                     /locus_tag="PB779_000579"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HDE0738124.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            16175..16573
                     /locus_tag="PB779_000580"
     CDS             16175..16573
                     /locus_tag="PB779_000580"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HDE0738125.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            16639..17721
                     /locus_tag="PB779_000581"
     CDS             16639..17721
                     /locus_tag="PB779_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0738126.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            17933..19495
                     /locus_tag="PB779_000582"
     CDS             17933..19495
                     /locus_tag="PB779_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738127.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            19488..20621
                     /locus_tag="PB779_000583"
     CDS             19488..20621
                     /locus_tag="PB779_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738128.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            20621..21577
                     /locus_tag="PB779_000584"
     CDS             20621..21577
                     /locus_tag="PB779_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738129.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            21676..22842
                     /gene="deoB"
                     /locus_tag="PB779_000585"
     CDS             21676..22842
                     /gene="deoB"
                     /locus_tag="PB779_000585"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HDE0738130.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            22866..23684
                     /locus_tag="PB779_000586"
     CDS             22866..23684
                     /locus_tag="PB779_000586"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDE0738131.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            23701..24408
                     /gene="deoD"
                     /locus_tag="PB779_000587"
     CDS             23701..24408
                     /gene="deoD"
                     /locus_tag="PB779_000587"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HDE0738132.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(24706..25392)
                     /gene="gpmA"
                     /locus_tag="PB779_000588"
     CDS             complement(24706..25392)
                     /gene="gpmA"
                     /locus_tag="PB779_000588"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDE0738133.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(25564..26145)
                     /locus_tag="PB779_000589"
     CDS             complement(25564..26145)
                     /locus_tag="PB779_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDE0738134.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(26278..26961)
                     /gene="rpiA"
                     /locus_tag="PB779_000590"
     CDS             complement(26278..26961)
                     /gene="rpiA"
                     /locus_tag="PB779_000590"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HDE0738135.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            27280..27693
                     /gene="rpsL"
                     /locus_tag="PB779_000591"
     CDS             27280..27693
                     /gene="rpsL"
                     /locus_tag="PB779_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HDE0738136.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            27777..28247
                     /gene="rpsG"
                     /locus_tag="PB779_000592"
     CDS             27777..28247
                     /gene="rpsG"
                     /locus_tag="PB779_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HDE0738137.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            28341..30428
                     /gene="fusA"
                     /locus_tag="PB779_000593"
     CDS             28341..30428
                     /gene="fusA"
                     /locus_tag="PB779_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HDE0738138.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            30600..31787
                     /gene="tuf"
                     /locus_tag="PB779_000594"
     CDS             30600..31787
                     /gene="tuf"
                     /locus_tag="PB779_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HDE0738139.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            32194..32502
                     /gene="rpsJ"
                     /locus_tag="PB779_000595"
     CDS             32194..32502
                     /gene="rpsJ"
                     /locus_tag="PB779_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HDE0738140.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            32533..33162
                     /gene="rplC"
                     /locus_tag="PB779_000596"
     CDS             32533..33162
                     /gene="rplC"
                     /locus_tag="PB779_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HDE0738141.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            33190..33813
                     /gene="rplD"
                     /locus_tag="PB779_000597"
     CDS             33190..33813
                     /gene="rplD"
                     /locus_tag="PB779_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HDE0738142.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            33813..34103
                     /gene="rplW"
                     /locus_tag="PB779_000598"
     CDS             33813..34103
                     /gene="rplW"
                     /locus_tag="PB779_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HDE0738143.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            34142..34975
                     /gene="rplB"
                     /locus_tag="PB779_000599"
     CDS             34142..34975
                     /gene="rplB"
                     /locus_tag="PB779_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HDE0738144.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            35018..35296
                     /gene="rpsS"
                     /locus_tag="PB779_000600"
     CDS             35018..35296
                     /gene="rpsS"
                     /locus_tag="PB779_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HDE0738145.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            35319..35666
                     /gene="rplV"
                     /locus_tag="PB779_000601"
     CDS             35319..35666
                     /gene="rplV"
                     /locus_tag="PB779_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HDE0738146.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            35680..36336
                     /gene="rpsC"
                     /locus_tag="PB779_000602"
     CDS             35680..36336
                     /gene="rpsC"
                     /locus_tag="PB779_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HDE0738147.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            36339..36773
                     /gene="rplP"
                     /locus_tag="PB779_000603"
     CDS             36339..36773
                     /gene="rplP"
                     /locus_tag="PB779_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HDE0738148.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            36763..36951
                     /gene="rpmC"
                     /locus_tag="PB779_000604"
     CDS             36763..36951
                     /gene="rpmC"
                     /locus_tag="PB779_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HDE0738149.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            36976..37242
                     /gene="rpsQ"
                     /locus_tag="PB779_000605"
     CDS             36976..37242
                     /gene="rpsQ"
                     /locus_tag="PB779_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HDE0738150.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            37300..37668
                     /gene="rplN"
                     /locus_tag="PB779_000606"
     CDS             37300..37668
                     /gene="rplN"
                     /locus_tag="PB779_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HDE0738151.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            37705..38013
                     /gene="rplX"
                     /locus_tag="PB779_000607"
     CDS             37705..38013
                     /gene="rplX"
                     /locus_tag="PB779_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HDE0738152.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            38041..38580
                     /gene="rplE"
                     /locus_tag="PB779_000608"
     CDS             38041..38580
                     /gene="rplE"
                     /locus_tag="PB779_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HDE0738153.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            38599..38784
                     /locus_tag="PB779_000609"
     CDS             38599..38784
                     /locus_tag="PB779_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HDE0738154.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            38820..39218
                     /gene="rpsH"
                     /locus_tag="PB779_000610"
     CDS             38820..39218
                     /gene="rpsH"
                     /locus_tag="PB779_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HDE0738155.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            39250..39786
                     /gene="rplF"
                     /locus_tag="PB779_000611"
     CDS             39250..39786
                     /gene="rplF"
                     /locus_tag="PB779_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HDE0738156.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            39947..40303
                     /gene="rplR"
                     /locus_tag="PB779_000612"
     CDS             39947..40303
                     /gene="rplR"
                     /locus_tag="PB779_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HDE0738157.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            40324..40824
                     /gene="rpsE"
                     /locus_tag="PB779_000613"
     CDS             40324..40824
                     /gene="rpsE"
                     /locus_tag="PB779_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HDE0738158.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            40839..41018
                     /gene="rpmD"
                     /locus_tag="PB779_000614"
     CDS             40839..41018
                     /gene="rpmD"
                     /locus_tag="PB779_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HDE0738159.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            41062..41502
                     /gene="rplO"
                     /locus_tag="PB779_000615"
     CDS             41062..41502
                     /gene="rplO"
                     /locus_tag="PB779_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HDE0738160.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            41502..42797
                     /gene="secY"
                     /locus_tag="PB779_000616"
     CDS             41502..42797
                     /gene="secY"
                     /locus_tag="PB779_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HDE0738161.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            42859..43506
                     /locus_tag="PB779_000617"
     CDS             42859..43506
                     /locus_tag="PB779_000617"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HDE0738162.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            43697..43915
                     /gene="infA"
                     /locus_tag="PB779_000618"
     CDS             43697..43915
                     /gene="infA"
                     /locus_tag="PB779_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HDE0738163.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            43948..44064
                     /gene="rpmJ"
                     /locus_tag="PB779_000619"
     CDS             43948..44064
                     /gene="rpmJ"
                     /locus_tag="PB779_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HDE0738164.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            44082..44447
                     /gene="rpsM"
                     /locus_tag="PB779_000620"
     CDS             44082..44447
                     /gene="rpsM"
                     /locus_tag="PB779_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HDE0738165.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            44475..44864
                     /gene="rpsK"
                     /locus_tag="PB779_000621"
     CDS             44475..44864
                     /gene="rpsK"
                     /locus_tag="PB779_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HDE0738166.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            44944..45882
                     /locus_tag="PB779_000622"
     CDS             44944..45882
                     /locus_tag="PB779_000622"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HDE0738167.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            45910..46290
                     /gene="rplQ"
                     /locus_tag="PB779_000623"
     CDS             45910..46290
                     /gene="rplQ"
                     /locus_tag="PB779_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HDE0738168.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            46562..47401
                     /locus_tag="PB779_000624"
     CDS             46562..47401
                     /locus_tag="PB779_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDE0738169.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            47377..48246
                     /locus_tag="PB779_000625"
     CDS             47377..48246
                     /locus_tag="PB779_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDE0738170.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            48236..49033
                     /locus_tag="PB779_000626"
     CDS             48236..49033
                     /locus_tag="PB779_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDE0738171.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            49236..49982
                     /gene="truA"
                     /locus_tag="PB779_000627"
     CDS             49236..49982
                     /gene="truA"
                     /locus_tag="PB779_000627"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDE0738172.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKVRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            50647..50884
                     /locus_tag="PB779_000628"
                     /pseudo
     CDS             50647..50884
                     /locus_tag="PB779_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299509.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(51028..51804)
                     /locus_tag="PB779_000629"
     CDS             complement(51028..51804)
                     /locus_tag="PB779_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDE0738173.1"
                     /translation="MNIHHIRNATAILDYGGKKFLIDPMLAEKGTLPPFISKGPFPSP
                     RKDQMNPLVDLPMPVEDIINGIDAVIVTHLHLDHWDDIAKEVLPKEIKLFVQDENDAN
                     EIRLYGFKNVEVLREDTVFESIQLVKTKGKHGRGEILNYVGNVCGIVFKHSTEKTLYF
                     TGDTVWYEAVKQTIDQYNPEIIVANAGDNHFLVGESLIMGKDDLYELHKAIPDSTIIA
                     VHMEAVNHWGLSREELKSFNKEKGISEKVLVPEDGDNIFI"
     gene            51927..>52266
                     /locus_tag="PB779_000630"
     CDS             51927..>52266
                     /locus_tag="PB779_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="HDE0738174.1"
                     /translation="MLDQTDINIIEELSKNSRITMKELGEKVHLTGPAVSARVTKLEE
                     SGVIENYTVKLNMEKLGFSIHAFLIIITQNLNHKPYLSFIKNHEKFLIRNYKISGGGC
                     YLLECRFTSKK"
BASE COUNT        16643 a         9411 c        11305 g        14907 t
ORIGIN      
        1 ctattgctag aataacatca aggaataata agttttggtt ttcagataat agtcgataag
       61 ttgtgtattg gaattttaga tacagtaata aagtattttt catgaaattt tgtgagaatc
      121 actattacaa gtatctttaa taaaattaat ggttaaggag gaacttaaag tagaatgtaa
      181 atgaatagtt gtagtcagtc gattgtgata ctagactcaa agttgcagga ataagttttt
      241 caatttgtga ttggaagata aaaaatgaaa aagaagggct tttttttata ctttgttgat
      301 tgtagtgttt attttccctc tgtttagcca agtaacattt tctatgactc aaccagtttc
      361 aagtgaggaa catgataacc tttttcgtgc tacagaagag tttaagaaat atcaggaaaa
      421 tattgttccg gagactccat tagctagtga gccaattact gatattgatg gaaaccaaat
      481 aggatggtat atacagtacg aagttatggt ggtaaataat gactcaatag taaaaaatac
      541 agtaggctta gagctaacac cgattgaaaa ggtgagttca ttgttaacgt atatttatac
      601 tgatgaaagt gacgagactg agatcatttt aacggattac tcaaaaattg ctactgataa
      661 aaagtatata ttgtggatgt agacactagt gaaatacttt atgatataga aattgatgaa
      721 aatttactag atgtagcaca agaaatcgat catcaaaagc aggaagctat tcgatatgct
      781 ggtagaaaag ggaaaagaaa atatttatta cgtgaatgta gcaaaagtta gagaagatga
      841 aaatgagtgg aaagaattca agagtcgcta ctcaattaac tcgactccga catttacagt
      901 ttacagagaa ggatcgatag aaaaaactgt tttttggact aaagaaagtg gaatgtcttt
      961 agctgaagta gaagagtttt tggattatgt tagtatgcaa cagtaaggga gttcttatta
     1021 tgaaaaattt tgacacatat tatgttattg ttttttcgat atctttgctg ttaatattac
     1081 taactttaat gcagtataaa gagtatccag agtattttat tttaactttt gtatatttag
     1141 taagtagcta cacacttcta tataaattca gaagttcttc tagagtttct aaagtttgtt
     1201 tcttaattag cttattgatt ctataatatt tttgatttat ataggaaatt aaaaatatta
     1261 tagaatcaac actcagagaa cgggttggtt tttaatagat ttaataagta ctgataatga
     1321 aatttctcct ggttgggaaa acgaagttgg ttaccctgta gaagaatttt ttcaagatta
     1381 ctttgcggag tatgccgata ggataatgag agattacgta acagataaaa ctcaagaagt
     1441 catcaatcaa tcccagtcat taaatgaatt atctgataag gcgaaagaag aagcagttgc
     1501 cattatttct tcagggatta gtgactatat tgatatgagt ggtgaaatca attatggcga
     1561 taaagacaaa attgtacgca tgataaaagc ttttatcaaa acttttgatg tgaaggcaga
     1621 tcttaagttt aatgatactt acctagtagg aaaattaatt aatatccttg ggacagagaa
     1681 agatacggaa acgtttattt cctctttgtc tatgttgttt acagataagc atttttcaac
     1741 tcagcttggt ggagaggaac tagtggaaat cttttaacca ttacgcccag cattaataaa
     1801 agtatatcaa aaaagtactc ctgatgattt ttaagattgg tttgagaaat aatgtgaaaa
     1861 cactattttt aatgttaatt atagatagag atgaacgcgt catatggtta aaagaatgaa
     1921 aaagtcaaag atacactgct atatttcact aaggatatag cagtgtatct ttcatgtcgt
     1981 ttcactggca gttttttata aaaggaggtg tgcatttcag ttgcttttct ttggtagtta
     2041 gttgaatcgt ttaagaatta acggatgtgg cagacaggtg ctctgtccaa aaaccagtaa
     2101 aatctttgat ggttccatct ttatttagct gtgcctgttc aaatactgtt ttgtttttac
     2161 cgaatggatc aattgcaata attgttccga tccccgcacg tttggcagca agtaatcctg
     2221 agtaagcatc ttcgataaca agacaatcag ccggagctaa gctcagtttg tctgccgctt
     2281 taagaaaaat atccggttgc ggtttcccag ggaaagagcc gtcgtcatag acaatcttgt
     2341 cccagtcaaa ccagcgggct aaatcgaaaa tatcaaaata aaaagcaaca ttctctttga
     2401 cagtagccgt ggcaatcgtt aatggaatct gttggtcagt cagctggtca agagtcgctt
     2461 caagcccttt tgtcaactga agctcgtttt cattttgcaa gcaaagcata cgataatagc
     2521 tttctttttc ttctgacaat acggcgatct cagaggcggt caaatgctct gaaatgaaat
     2581 gtttcaaaat ctccgtattc gtccgaccat gaatattttt taaaatatcc tcgtctgata
     2641 aaccatcttt tgtatgatca tgtatcatat gcagccaagc agcttcatgc agatgagagt
     2701 ccaaaaacat tgttccgttg aaatcaaata taatcccttt catagttacg ctcctatagt
     2761 ggtattttcg gttgaatcag caatttgcag atcgacatat tgtgcatagt gctcttgaac
     2821 ctcccgcgag atctggcgat ccgtaatgag cagatcgaaa tcatgcaaat tataaaacac
     2881 ataaaaatca tctcgattga attttttatt atcaacgagt agatatttct tacgggaatt
     2941 atttagagcg atctgctgtg cttctccttc ttcggtactg taagtagaga tcgcttcgtt
     3001 gtgaacgcca tttgaactga taaatgcttt tgtaaacttt agtcttctta aattgtcgtt
     3061 ggtgatcggt ccgacaaatg cgccggtatt tttccggaaa tcaccgccaa tcagtagaat
     3121 ttctggtcca tctgcttgag caagaatatc aaaaactgga taattatttg taatgatccg
     3181 aattttcttg ttcagtaaat gcgtcgccaa tagttcgatt gttgtacctg gtcctaagaa
     3241 aatcgtttct ccctcgtgaa tcaaggaggc tgctgtggca gcaatttctt ttttttcttg
     3301 aatctgcaga gtggcttttt cagtgtgaga aagttcttga tctaaagtgt aggaaagact
     3361 ttgagcccct ccatggacac gcagcagctt gcccgatttt tctaattcat ctaaatctct
     3421 gcgaacggtc atatcagaaa catctaattg attgatgatt tcattaacgg taaggattcc
     3481 ttttttattg accatttcta cgatagtaag caatctttct tttttcaaca ttgtcttcac
     3541 ctctaattta aggataatct atcatataaa cggacaacag tcaatctaat tcgaacaaaa
     3601 gtaaacattt agggtggttt ttatgtttgt tacaatagat tttattgctg ttttctggtt
     3661 tttatgatta tttgtgtttg tttttgttga caaatgtttt ggatgcgttt acaatgcaat
     3721 cagttagaaa gagcgaaaac tgattataga tttgaggaga gatgtacatg cttaaattac
     3781 cagaagattt tatttttggc ggagccacag cagcctatca ggttgaagga gccactaagg
     3841 aaggtggcaa aggcgctgtt gcttgggatg actttttaga ggaacaaggg cgattcagtc
     3901 ccgatccggc aagtgatttt tatcatcaat atgcaaagga cattgaattg tgtgaacgtt
     3961 ttggtgtaaa tggtctaaga ttatccattg cttggagccg catttttcct gatggagctg
     4021 ggaaaccaaa tccagaagga atcgcttttt atcatcgtgt gttcgaagaa tgtaagaaaa
     4081 gaaacgtaac gccgtttgtg acgttgcatc attttgatac ccctaaacgt ttgtttgacc
     4141 atggagattt tttgaatcga gaaacaatag aagcatttgt ttcctatgcc attttttgtt
     4201 ttcatgaatt caaagaagtc aaggtgtgga gtacctttaa tgaaatctat ccagttgcaa
     4261 ccaatcaata tttgttaggt gttttcccac caggaatcaa atatgatttt acaaagatcg
     4321 tcgcctgtct tcataatatg atggttgctc atgcccgtgt agtgaactat ttcaaagaaa
     4381 acgaacttcc gggtgaaatt ggtgtagttc actcattaga gacgaaatat gcggcaacag
     4441 acgcgccgga agataagcat gctgcctttt tagacgatgc attgtcgatc cgtttcttat
     4501 tagatgctac ctatttaggc tattattcaa ctgaaacctt gactgctctt gatgagatat
     4561 gtgaagcaaa tcaggccagc tatcattttc ctgaagaaga tttcgttgaa ttgaaaaaag
     4621 catccacgcg taatgactac ttagggatca atcactacca atgccatttt gtcaaagctt
     4681 acgatggaga aaatgcaatc catcataacg gtacgggtga aaaagggacc tctgtttata
     4741 aagtgaaggg aatcggagaa cgtatttata aagaaggaat tcctcgaact gattgggact
     4801 ggctgattta tccagaaggt ctatatgact tgttgctgcg aattaaaagc gattacccac
     4861 attacaacaa aatctatatc actgagaacg ggatggggta taaagatcag tttgaagatg
     4921 gcattattat ggatcagccg agaatcgact atttgagagt ctatttggaa tccttaagca
     4981 aggcgataac agccggggta aatgtgaagg ggtatttttt gtggtcgctt atggatcttt
     5041 tctcatggac aaatgggtat aacaaaaggt atggcttgtt ttatgttgat tttgaaaccc
     5101 agaagcgtta cccaaaagaa tcagcttact ggtacaagtt ggtcagtgaa accaaaacga
     5161 ttatttaata agtgataatg gaggaagaaa agatgaataa agaggaatta caaatgcttg
     5221 gttttgagat cgttgcatat tcaggcgacg ctcgcagtac attattgaaa ttattgaaag
     5281 aagtaagaca aggaaacttt gaacatgttg attcggcgtt gaaagaagcc gacgaaaatt
     5341 taacccttgc acataattcg caaacaaaaa ttttagcgga agaagcatct gggaaagaga
     5401 tggagatggg attcattttt atccatgggc aggatcattt aatgaccact ttattgctga
     5461 gagatctgat tcaagacttt attgtactgt acagacagaa tcaaggatag gagaagaacg
     5521 ctatggatgg aatcattaaa caaatcgaaa aagggaaacc attttttgaa aaaatctcac
     5581 gtaatagtta tttaggagcc gttcgtgacg gatttttaac agcgatgcca gctattttat
     5641 tttcaagcat tttcattttg attgctgcgg ttcctgagat ttttggttac caatggcctg
     5701 aatctgtctc cacatggcta tggaaagtct ataattattc gatgggtgtt gtagggttac
     5761 tcgtttcagc aaccactgct cgctgcttgg ctgattcgat gaatcgtcgc ttaccgaaaa
     5821 acaaagtaat caacaccacc tctgtgatgc tggcctctgt ggtaagtttc ctgttgttaa
     5881 gcgtctctcc gattgaaggt ggattttcaa cggaatatat ggggacaaag ggactactgg
     5941 cttcctttgt cgctgcattt ttaacagtta atttatataa gttttgtgtg ctgaaagata
     6001 ttaccattaa aatgcctaaa gaagttcctg gaacgatttc gcaaaccttc cgagatattt
     6061 ttcctttctc tttttcagta tttgcggccg ttttaattga tttaggcatt cgacaaatct
     6121 tccaaatctc atttgcagaa gcaatcatta cggtgctgca gccgctattt acagcagctg
     6181 acgggtactt aggaatcgct attatctggg gagcgatggc gctgttttgg tttgtcggtg
     6241 ttcatggacc gtcgatcgtg gagccggcaa ttgcggcaat tatctatgcc aatgtggaaa
     6301 ccaatctgca attgttcaat tccggtgaac aagcttctaa agtactgacg gtgggtttag
     6361 ggaattttgt aggaactatg ggaggaactg gggcaacatt ggttgttcct tttatcttcc
     6421 tactctttgc taagtctaag cagttgaagg cagttgggaa agcttccttt attccagtaa
     6481 gtttcgctgt caacgaacca ttgctatttg cggcacccat gattttgaac ccttattttt
     6541 ttattccatt tttgttaaca cctgttgtaa acgtttgcct gttcaagttt tttgtcgatg
     6601 tattgggcat gaacagcttt atgtacgttt tgccttgggc aactccagca ccgatcggtt
     6661 tggttctagg aacgggcatg ggtatcttag cttttgttct agcagcggtt ctaatcgtcg
     6721 ttgacttcct gatctatcta ccattttgca aagcatacga tgctgtctta gtagagaaag
     6781 aagcacaaaa agcagaggtg atcgcaaccg aggaaggtgc ttctgccgat gtacgtgagg
     6841 aagtacctgt ggcagcgagt caagttatca gcgatgcaaa taaagaaatc aatgtgttgg
     6901 tactttgtgc tggcgcaggg acaagtgcga tgttagctaa tgctttaaaa aaaggtgcat
     6961 ctgaatcgaa agcaccgatc agtgcaatgg cgggtgctta tggttctcat tacgaaatgc
     7021 tgcaggattt tgatatggtg gtcttagcac cgcaagtcaa ttcttactat gatgatatca
     7081 aagaagacac cgatcgctta ggaatcaagc tggttgcgac aaaaggagca gaatatatcg
     7141 gattaacgag agatcctgaa aaagctgttc agtttattct gaaccaattt caataaagga
     7201 ggagccataa tgaaaatggg aatttggttg cgtaaagctg ttttatttgc agctgtgtta
     7261 ggggctttgg gggctgtttc aaaaactgtt gaagcatctg ccagcgaatt tattcgcgga
     7321 gcagatattt cgatcctgtc agatatggaa aaatctggtg caaaatatta tgaagacgat
     7381 atttcaaaag atgccttaga gattttaaaa aataatggtg tcaactatgt tcgactgcgt
     7441 ttgtggcagg atccttataa tagtaatgga gaaagttatg gagcagggac aaatgatctg
     7501 gaaacgacga ttgaccttgc aaaacgagca aaaaatctgg gacttaaggt gctgctggat
     7561 tttcactaca gtgatttttg ggttgatcct gggaaacaga atcttcctaa agcatggcaa
     7621 ggtctgacct ttgaagaaat gaatacggca ttgtacgact atacaaagaa cgttctgtcg
     7681 gaaatgaagc agctggacgt ttatcctgat atggttcaga tcggcaatga actgaatagc
     7741 ggaatgctct ggccttatgg caagtcttgg ggagaaggcg ggggagaatt tgatcgattg
     7801 gctgcttttt tgaagtctgg tatccaagct gttcgagaca ctcaacctaa aacaactcca
     7861 gtaatgctcc acttagctga tggtggcgat acaggagcat ttacttggtg gtttgatgaa
     7921 atcacgagtc gaggtgtgtc atttgattta attggagtgt cgtattatcc gtattggcac
     7981 ggttcaatga atgaacttca aaccaatatg aatgcgatca gccaacggta tggtaaagaa
     8041 gtgatcgtag ttgaaacagc ttatgggcat acaacagcga atgccgatac tatgccaaat
     8101 gcttttggtg aagccgaagc agctgcgggg ggatatgaac caacaccgac aggacaagca
     8161 gagtatttgc tggatcttgc cgatcggatt caggcagtac cgaataatcg cggggcgggc
     8221 ttcttctatt gggaacctct ttggtacaac ggaaatgtga gttgggcaac acaagcaggt
     8281 atgaattatc tcagtgttca atccactatg ggaaacgaat gggacaacca agcgatgttt
     8341 gattttgctg gaaacgcctt gccaagcttg cgtgcgttta aacaagcagg ggcgcaaata
     8401 aatctagtta aaaatgcaag tttcgaaagc gatggaccaa cgaccagtcc ttccaattgg
     8461 caaacctggt ttcaacaagg aaccgctaag ggtacgatca aaacggaagc gggcactttt
     8521 tttggggact acaaactaac tttttggcag gatcaagcat acgaggcatc agcttatcaa
     8581 aatgttagtg gcataagcaa aggaacttac acattgagtg cctatgtaat gtctggggga
     8641 gagtttgata ctaatcagtt atatatcaaa aattatggtg gagcggaact aaatactgcg
     8701 gttgttaaaa caagtgaatg gacaaaaatt acaatcaaag acattccaat tacaacaggt
     8761 gtttgtgaaa ttggggttta tagcaaggct tcaggaaatg cttggacgaa cgttgatttt
     8821 gtttcattgg tgaaacaata gactgcggat cgtttcgatt caagatcgga ggttcccttc
     8881 agccacatcg ttagcgtaga aggcaggaat cgaacctgca cctcgccttt gccaaaaata
     8941 accagaaacg atttccagtc atttttacca aaacgagtaa agcaccagac ttcatctaca
     9001 ctttgtatta tgctaaagag agttcaacga tttcgtaaga agcaatgaaa aaattgcaaa
     9061 aagttgtgca gataacataa agtttgttta agaaagggta accttagaat tccgtcgtga
     9121 atatgatttg agcacttaga tggatagaaa aaagttctcg gaaaacagtt cgtttttcga
     9181 gaacttcttt ttatgataag aatgaaacaa attaacttat attatagtct cttttggtag
     9241 ggaaccatct tatttttaat gaaaatcaag cattttagct attgaagaat gttgatttat
     9301 agggattccc cctccatatt atgttggctc tttattccca ctccactgtt gctggtggtt
     9361 tagaagtgat gtcatacacg atacggttga cgtgggctac ttcgtttacg atacgtacag
     9421 agattttttg caagacttcc catgggatac gggcaaagtc agcggtcatt ccgtcgattg
     9481 aagttacagc acggataccg actgtgtagt cgtaagtacg tccgtcaccc ataacaccga
     9541 cagagcggat ccctggaaga acagtgaaat attgccagat atcacggtca agtccagcag
     9601 ctgcgatttc ttcacgcaag atagcatcag attcgcgtac gatttctagc ttgtcttcag
     9661 tgatttcgcc aagaacacga ataccaagac caggaccagg gaatggctga cgccaaacga
     9721 ttgaatcagg catgcctaac tgagtcccta attcacggac ttcgtctttg aataatgtgt
     9781 ttaatggttc gatcaattca aattgcatat cttctggcag tccacctaca ttatggtgag
     9841 atttgatcgt ctgtgctgtt tctgtaccag attcgataac gtcagtatac aacgttcctt
     9901 gtgctaggaa agagacgcct tcttcaccag caagttttgt tgcttcgtca tcaaaaacat
     9961 atacgaattc attcccaatg attttacgtt tttgttctgg gtcagataca cctttcaact
    10021 tgtctaagaa gcgatctctt gcattgactt tgatgatgtt caagccgaat tttccgccta
    10081 gactttccat tacttgttcc gcttcgcctt tgcgtagcag accgtggtca acaaagatag
    10141 atgtcaattg gtcaccgatc gctttttgta aaagaacccc aacgacacta gaatcaacgc
    10201 cacctgaaag accaagcaag acttttttgt caccaacttg ttcacggatt ttttctactt
    10261 gcatatcgat aaagttatcc attgtccagt taccttcaca gtgacaaaca tcaaaggcaa
    10321 agtggcgcag caattcgatt ccgtattcgg aatgacgtac ttctgcatgg aattggatac
    10381 cataaaaatt acgtgttgtg tcttggatag aagcaatcgg acaatctttg cttgttccga
    10441 ctgtttcaaa gccttcagga actttagtta ccaagtcacc atggctcatc catactgttt
    10501 gttgttttgg tgtttcttta aacaagacag cttgatcgct tgttacttct aacaaggctt
    10561 tcccatattc gcggttttta gcaggctcta cggaaccgcc aagtttgtac gtgatcaatt
    10621 gcataccata gcaaatccct aatacaggaa tacctaaatt gaagatctca ggatcgatcc
    10681 caaatgcatt ctcatcatat acactgtttg gtccgccaga aagaatgatt ccctttggat
    10741 tcatcgcttt tacttcttct gcagtaatgc ggtggctcaa taattcggaa aagactccaa
    10801 gatcacgaat acgtcttgtg atcaattggt tatactgact accgtagtct aatacgataa
    10861 tcttttcaac gttcgtcata tcggcaacgt ttgtcaaatt tattacccct atccctttaa
    10921 attttatctc aaaatagtca aactatttta aaatgctaat attttcgcat gaaaatcgaa
    10981 tcgatgatat gattttcagt tttatggaga attatatcgg ctcttcctcg tgtaggcaag
    11041 atatattcct gtaaattttt caaattcaca tttttccata catcttttgc cattttaaag
    11101 gcttcttcac gatctccgat agcaaaacga taataataat tctctggatt ttggaaagcc
    11161 gtatccagta acgcaccaaa acgatccaaa taccattttt cgatcagcac gggatcggca
    11221 tcgacataga cagaaaaatc aaaaaagtcg ctgacgtaga tttgctgatt cgcaggtaat
    11281 tgaagcgtat tgatcccctc aacgatcaag atatcaggct gctggatcaa ttcgtacttg
    11341 tctggaatga tatcatacac atcatgtgag taaacaggta cttttatctc ttcctgacca
    11401 gattttacac ggttcaagaa atcgatcagc atctccatat cataactttc aggaaatcct
    11461 ttacggtcca tgattccacg ctcttttaat atacgatttg gataaagaaa tccgtcagtc
    11521 gtgatcagct gaacgtttct tcgtttgaag gtacgagaca aaatcgtctg cagcagtctg
    11581 gctgttgtac tttttccaac ggctacactt ccggcgatcc cgataataaa aggcggtact
    11641 tctacgtatt tatgaagaaa taaaccttta ctcaagaaca aagattcaaa ttctttcata
    11701 taaagataaa tcagatgagc aagaggtaca tagatatctc gaacatcctg catggaaatg
    11761 cggtcattca aacttttgat attatctagt tcatcttgtg tcaaaggtgc ttgcccatta
    11821 cgataaaatt ctcgccattc ttctcttgcc acacggtagt agttcattgg atcattcata
    11881 ttagcctcct gcgttctccc atcaatggaa ctattttaac acaaaataaa cgcaaacccc
    11941 accacttaag agagattgcc gatctttttg tataatcttt ataatagaaa gaaacggagt
    12001 cttattcttg acttgcgcac ggatacataa aaggatagac tgttgtcatg aaagaaatga
    12061 gaaggatgga agacatgaca aatcattact attctgaacg cccagatacg gcgcacgatt
    12121 ttgaacaatg ggcttttgag ttaaaaggca gaacctttca atttgtaaca gattctggtg
    12181 tattttcacg tgaaacagtg gattatggtt cacgtgtcct gattgatgct ttcgattggg
    12241 aagagttacc tgatgaagga aagatcttag atgtgggatg cgggtatgga ccgattgggt
    12301 tagctttggc atttgcgaca cagcggtttg ttgaaatggt cgacattaat gaacgagcgg
    12361 taagtctagc gcaaggaaac gcaaagcgta accaaatcga acatgttgat atccatcaat
    12421 cgaatatcta tgaagcagtt catgaagaaa cctatgcagc tatcgtaagc aatccgccga
    12481 tccgtgctgg aaaaaaagtt gtacatgaaa ttttgacagg cgcatatcct cggttgaaga
    12541 agggcggtac actgacaatt gtgatccaga agaaacaagg agcgccgagt gcgcaaaaga
    12601 aaatggaaga aacatttggt aatgcagaaa tcgtcacaaa agataaagga tattatatca
    12661 tcaaaagtgt gaaagaataa ctagctgaaa aatagtggag cgacgaaaga gtggaactgg
    12721 gcgtgcatgt acgggtacgt atcagttctt tttttgttga gaagttttta aaaacaaaga
    12781 actatttttt cttcaaaaag aaatagtagg aacagagtcg ttgtttttta cgataaaata
    12841 aataagatac agaacttgta tagaaggctg ccaagtcggt agataaagga ggtttttatc
    12901 aaaaaacata ctttcctttt ttctctattc ttttcttggg ggttttggta cactgatagg
    12961 gaatttagat agaagggagc caataggatg aagctgacca tcagagatat cgcagaaatg
    13021 gcaggcgtat cagtaacaac tgtctcacag attttgaata acaaaggaag cagatttagt
    13081 gataagacaa gaaaaaaagt gttgtcgatc gtgaatgaac atcattataa gcccgattat
    13141 ttcgcttcaa atgtgatcaa tcgacattca aagaccatcg gaatgatcgt ccctgatgtc
    13201 actgatttct tcttctccaa actgatcgaa ggtgtagaga gctatttgaa tcctttgggc
    13261 tatgtgatca tgttatgcaa ttctcgtcat agccaagaaa atgagatcaa gtatttacaa
    13321 gagctttccc accgctcagt ggacggaatc ttgctggcca caccaaatat tttacctgag
    13381 aaatatgcat tagacagcgg tttttatcaa aaaatgccaa tcattttaat cgatcgcgga
    13441 ttgaatcgtc gggataacgg acggcttatc gtaaaggaat atgagggcgc ctatcaagct
    13501 gtttcgctgt ttattgaaaa tggccatacg aagatcggca tgctgaagga aaccactgga
    13561 tactatcaat tagaagaacg tttcaacgga tatcgtcatg cgctgaaaga tcatggcctg
    13621 ccttttaatg ggaaatttgt tgaacatgga gagttgactg tccaaggtgg atatactgca
    13681 tcaaaaaaat tactcaaaca taaagatatc acggctattt tttgcgggaa tgatgccatg
    13741 gcgatcggat gctatcaggc gatcgatgaa ttgggcaaaa aaatcccaga agatatctca
    13801 gtcataggat tcgatggatt aaagctgtca gaatacatga ttccgcaatt gacgacagtg
    13861 cagcagccaa gttttgatat tggattttat gctgcacgtt tcctgatcga tacgatcgaa
    13921 tttcctcaaa gaaaagttcc gaacaaagtg ttcgaaacaa aattaattat tcgtgagagc
    13981 gtaaaagtat tgacaaaggg ctaactcggc ggtatattgc ttatgtaagc atttacaaag
    14041 gctagttagt gcttttttta tttttagtaa accagtttac taaagtggtt tacctttcct
    14101 aaaaataatg tataataccg aatgaagaca aggaggatca ggcaatgcga atggtggatc
    14161 tgattgaaaa aaagagggat ggaaacgagc tgtcgaaaga ggaaatcgag tacatcgtca
    14221 cgaactatac gaatggaaag attccagatt atcaagtcag tgcattattg atggcaattt
    14281 tttatcaaga catgacaaat gaagaaatca cgaacttaac attggcgatt gctaattctg
    14341 gtgatgtcat cgatttgagt tctcttgaag gaataaaggt agataagcat tcgacaggtg
    14401 gcgttggtga cacgaccaca ttgattttag cccccctagt agctagtgtc ggagtgacag
    14461 tggctaaaat gtctggacgc ggtctaggtt acacaggtgg tacactagac aagctagaag
    14521 caattcccgg atttcagatc gagctttcgg atgaagaatt tgtacgcatt gttaatgaaa
    14581 gtaaagtagc ggtaattggt caatcaggaa acttggcacc ggcggacaaa aaattgtatg
    14641 ccttgcgtga cgtcacagcg accgttgatt ctcttccgct gattgccagt tcgattatga
    14701 gtaaaaaaat cgcggcagga gcagatgcaa tcgttttgga tgtgaccact ggagacggtg
    14761 ctttcatgaa gaacatcgaa gatgcaagac gtctggcaaa gaccatgacg agcattggga
    14821 aactggctaa ccgagaaaca gtggcggtta tctcagatat gtcagaacct cttggcgaag
    14881 ctatcggaaa tagtctagaa gttgtcgagg caatcgaaac attacaagga aatggtccag
    14941 aagatctagt agaaatgtgc tacgccttag gaagccaaat ggttgttctt gctggcaaag
    15001 ctaagacaac cgatgaagca agaacgttgc ttcaagaagc tctggaatca ggtaaagcgt
    15061 tagcaaaatt caaagaaatg atccaaaatc aagggggaga cccagcgatc gtggaacatc
    15121 cagaacgaat tttgactgca cgctacacaa tggagcttcc tgctaaacaa agcggagttg
    15181 tgtcaaaaat cgtggcaaat gaattaggaa ttgctgcaat gatgctaggt gctgggcgta
    15241 aaaccaaaga agaagatatt gatcacgctg ttggattgaa actgcataaa aaaattggtg
    15301 acactgtgac aaaaggtgag tcactattga cgatctatag taacgacgaa gaaatcactt
    15361 ctgtcattga attattatat aaaaatattg aaattggtga atcggcaatg aagccaacgt
    15421 tgattcatga catcatcaca gaataaagga aaaaagcgga ctttaccgtt ttaaagaaaa
    15481 ggggaaaaga aatggaacta aaccgaatga tcgaccatac tattttgaaa gcagacgcat
    15541 ctaaagaagc tgtgatgcaa attatcgaag aagcaaaaaa ataccatttt tattctgtct
    15601 gcatcaatcc agcatgggtt gcgctagcga aagaacaatt acaaggtgag ccagtagccg
    15661 tatgtacagt aatcgggttt cctctaggag caaacacacc cgagacaaaa gcatttgaaa
    15721 caacagatgc catcaataac ggtgcagatg aagtcgatat ggtcatcaat atcggtgctt
    15781 tgaaatcaaa ggatgatcaa caagtccaaa aagatatcga agcagttgtt gaagcagcaa
    15841 aagatcgtgc gcttgtcaaa gttattattg aaacatcgtt attagataga gaagaaatca
    15901 tccgagcttg cgaaatagca aaagctgcag gcgctgattt tgtcaaaaca tcaactggtt
    15961 tctcaacagg cggagcaaag gtagaggatg tccgtttgat gcgtgaaact gtaggaccag
    16021 aaatgggtgt caaagcttcc ggcggtatcc ataacgaaga agaagcaatg gcaatgatcg
    16081 aagctggtgc tacaagaatc ggaacaagcg caggagtagc aatcgtatct ggttcaactg
    16141 gtgaaggcta ttaatttttt caaaggagaa gctcatggca gaactcaaac aagaatggat
    16201 caacacagct attgaagcgt tagataaagc ctatgttcct tattcccatt ttccggtagg
    16261 cgcttgtctc gtaacggaat caggcaagat ttatcaaggc atcaacattg agaatgcatc
    16321 atttggatta acgaattgtg ccgagcgcac agcttttttc aaagcagtat ctgaaggaga
    16381 aaaaacattt acgcatctag tcgtagcggg gcacaccccc gatcctatct ctccttgtgg
    16441 tgcatgtcga caagtaatgg cagaattctg ttcccctgat atgccggtta cgctagtagg
    16501 agacaatggt gtgacgaagg caacgaccgt tcgtgcactg ctgccttatg catttactga
    16561 aaaagatcta taactcatgt tcattcagtc agctgactgt tgaaaaataa aacaattatt
    16621 ttaggaggct ttacagaaat gaaaaaagca aaattatttg gtttaggtgc tgtcgcacta
    16681 gcagcagggt tatttttagg tgcatgcggc aacaacggct ctactgattc atccggtggc
    16741 aaaagctcat cagacacaac aactgcagca ttgatcacag acacaggtgg tgtagacgac
    16801 cgttcattca accagtcagc ttgggaagga ctagaaaaat gggggaaaga tcaaggactt
    16861 tcacgaggaa atgatggctt ccaatatttc caatcttcaa atgaatcaga ttacatccca
    16921 aatattgacc aagcattgaa tgctggattc aaaacgattt ttggtattgg ttataaacta
    16981 aaaccagcga tccaagaaca agcaacaaac aatacaggta cgaactttgt tattatcgat
    17041 gatgtcatcg atggattaga taacgttgta tctgcaactt tcaaagacaa cgaagcttct
    17101 tatcttgcag gtgttgcagc agcttatacg actgaaacaa acgtagtcgg ctttatcggc
    17161 ggtgtaaaag gtgaagtaat cgatcgtttt gatgctggat tcaaagccgg tgttgatgca
    17221 ggtgcgaaag aattaggaaa agaaatcaaa gtattgaatc aatatgctgg tgacttctct
    17281 gctccagata aaggacgttc aattgctcaa ggtatgtatg cacaaaacgc agatatcatc
    17341 ttccatgctt caggcggtac aggtaacggt gtattccaag aagcaaaatc attgaacgaa
    17401 tcaggcgaca aaaaagtttg ggttatcggt gttgaccgcg accaatcaga cgaaggcgaa
    17461 tacacattaa acggcgaaaa gaaaaacttc acattgacat ctacactgaa agcagttgga
    17521 acagtagtag aagatttggc acaaaaatca gcggacggta aattccctgg cggcgaacac
    17581 actgtttatg gattgaaaga agacggtgtt ggtctaacag aaggacaact ttctgacgaa
    17641 gcgaaaaaag cagttgatga agcaaaagaa aaaatcattt caggtgacgt aaaagttcca
    17701 gaaactcctg aagaaaacta aaaccatttc tatagccttg ttagacacat gtttgacaag
    17761 gctatggttt gattagaaca agaattgttc atttatccaa gctgccttgt gacagtttgg
    17821 ataagggaac aactccctga agtaatgttt gtttcaaaag aagaacgctc actaagcgtg
    17881 aatcttagtc aatcgttgcc ctagatagaa atcgttagga tgtgaaaaaa aggtggttca
    17941 agaaaatatt gtcatagaaa tgcagaatat taccaaagaa tttggaacat tcaaggcaaa
    18001 tgacaacatc aatttacaag taaaggcagg agaaattcat gcgttgcttg gagaaaacgg
    18061 tgctggcaaa tctacattga tgaacgtgct ttccggatta ttagagccga catcagggaa
    18121 aattttgatg cgtgggaaag aagtaaagat cacaagtccg accaaagcca accaattagg
    18181 gattgggatg gtccatcagc actttatgct tgttgatgcc tttactgtaa cagaaaacat
    18241 cgtgttggga agcgagccta gtcgcgcagg gatgcttgac cataaaaaag cacgaaaaga
    18301 gatccaaaaa gtttctgaac agtatggatt gtcagtcaac ccagatgctt acgttcgtga
    18361 tatttcagtt ggaatggaac aacgggtaga aattttaaaa acactttacc gaggagcaga
    18421 tgtactgatt tttgatgagc cgacagctgt attgacccct caagaaattg atgaattaat
    18481 cgtgatcatg aaggaattag tcaaagaagg caagtcgatc attttgatta cgcataagtt
    18541 agatgaaatc aaagcagtag ctgaccgctg tacagttatc cgccgtggaa aaggaatcgg
    18601 tacagtcaac gttaaagacg taacctcaca acaattagcc gatatgatgg ttggaagaac
    18661 ggtttcattc aaaacgatga aaaaagaagc gaagcctcaa gaagtcgttt tgtctattga
    18721 aaatctagtg gtgaaagaaa atcgtggatt agaagccgtg aaaaacttga acttagaggt
    18781 tcgtgctggc gaagtacttg gtatcgctgg aatcgatgga aacgggcagt cggagttgat
    18841 ccaagctttg actggtttgc gaaaggcaga aagcggacat atcaagctaa aaggggaaga
    18901 catcactaat aaaaaacccc gaaaaatcac tgaacatggt gtaggacacg tgccagaaga
    18961 ccgtcataaa tacgggttag tcctagatat gacattatct gaaaatatcg cactacaaac
    19021 ctatcatcaa aaaccttaca gtaaaaacgg catgctgaat tattcagtaa tgaatgaaca
    19081 tgccagagaa ttgatcgaag aatatgatgt tcgaacaacg aatgaacttg ttcccgcaaa
    19141 agctttatca ggcggaaatc agcaaaaagc aattatcgct cgtgaagtcg accgagatcc
    19201 tgatctgttg attgttgcaa atccaactcg tggactggat gtaggtgcga tcgaatttat
    19261 tcataaacgt ctgatcgaac aaagggacaa atacaaagca gtgttactga tcagtttcga
    19321 attagaagaa attttaaatg tttcggatcg tattgctgtt atccatgaag gagaaattgt
    19381 cggtatcgtt gatccgaaag aaacatctga aaatgaatta ggtctattga tggcgggcta
    19441 taccttagaa gaagcacgaa aagagttaga aaagggggct ggcgcacatg aatgatcgca
    19501 gcgaaaaatt ccgtaattta ttagtgcctg tactttcagt tgttttagga ttgatcttag
    19561 gcgcgatatt gatggctgct tttggttttc agcccatcca aggttattct tctatgctag
    19621 atgcagccct tggttcgcaa agagggatag gtgaaacgtt aaggcaagca acgccgttga
    19681 tttttacagc attaggtttt tctgtagcta actcagctgg gtttttcaat attgggcttt
    19741 ctggacaagc actttgcggg tggatcgtca gtgtctgggt ggcacttgcg tttccagatc
    19801 tgccaaaagt tgttttgctt ccgttatgcg tgatcttagg tgccttagct ggtgcgatgg
    19861 cagcggctgt tccaggttta cttcgagcat tttttggaac aagtgaagtg atcgtaacaa
    19921 tcatgatgaa ctatatctta ttatacgtaa gcacatttgc tttacatgaa gtgatgcctg
    19981 aaagctatcg ctcaagtttg gactcttcca atatgatcag tcaaaatgcc tcactgcggt
    20041 taccatggtt aacacaagct tttggcggct ctcgcgtaaa ctcaggatta tttttagcaa
    20101 tcatcgcgct tattttcgtt tggctgctga tgaagaaaac gactttagga tttgaaatcc
    20161 gttctgttgg attgaatcct tttgcttctg agtatgcagg aatgagtagt aaacgtacga
    20221 tcgttttgtc gatggtcatt tctggcgctt tggcagggct tggcggtgtg gttgaaggat
    20281 taggaacgta tcaaaacttc tttgttcaaa cgacttcgct atctattgga tttgacggaa
    20341 tggctgtttc cttgcttggt tctggatcag caatcggtat tcttttatca gcgatcttgt
    20401 tcagtatttt gaagatcggt ggacttggca tgcagacagg agcaggtgtt ccgtttgaga
    20461 tcgtcaatgt atcgattgct ttgattatct tctttgtcgg gatcaacttc ctgattcgtt
    20521 tcgtcatggc taaagtcttc caagggaaaa aacaagaaga gatcgttgcg acaatagaat
    20581 cgaaaccaac gaatcaaaac catgaagggg gcgaactata atgtcgacta tcgaattaat
    20641 tgccttgatc cttacttcta cactggttta ttcaacaccg ctaattctaa cgtcactagg
    20701 cggaactttt tctgaacgaa gcgggatcgt aaacgtaggg ctagagggaa tcatggtcat
    20761 gggtgctttt agttccatcg ttttcaactt gacgatgagt ccatcacttg gttctatgac
    20821 accatggatc gctattttag tgggtggcgt cgtaggtatc ctattttctc tgattcacgc
    20881 agtagcaaca gtcagtttgc gtgctgacca tattatcagc gggacagtaa ttaatctgat
    20941 ggcacctgct ttaggtgttt tcttgatcaa agcatggtat ggtaaaggtc aaactgataa
    21001 catcacgcag aatctggggt atttttcttt cccaggatta gcagatattc cggtcattgg
    21061 accaattttc tttaaaaata cattcttacc tgcttattgt gctattttga ttgctgtcct
    21121 agcttgggtg atcatcttca agacgaaatt cggcttgcgc ctccgttcag ttggtgaaaa
    21181 tcctcaagct gccgacacat taggtatcaa tgtatatgct atgcgttatt caggcgtact
    21241 gatttctggc ttgttaggcg gtatgggcgg tgctgttttt gctcagtcga tttccggtaa
    21301 cttttcagct ggtacgatcg ttggacaagg gttcatctcc atggctgcta tgatctttgg
    21361 taagtggaat cctttagggg caatgggtgc ctcattgttc tttggttttg ctcaaagctt
    21421 gagtatcatt ggcgcacaat taccagttat ttcttcgatt ccgccagtat tgctgcaaat
    21481 tgctccatat ttgctgacaa tcattgtgct ggttgttttc ttagggaaag cttctggtcc
    21541 aaaagcaaac gggaagaact atatcaaatc aaaataatct tttagcgaat aaaaagggtg
    21601 ggttacggga agtgtttttc gtctcgccct ttttgtttta aaggcaataa aaataaaaag
    21661 aaagaaggaa taatcatgtt taaacgcgta catctgatcg tcatggattc agtaggaatt
    21721 ggagaagcac cagatgccga taagttcggt gatgttggtt ctgatacatt aggacacatt
    21781 gcgaaagaag caggattgaa cgttccacat ttagagcagc ttggtttagg aacgatccgt
    21841 cctcttgaag gtgtggaatc agtgaaagat catcaaggct atgcgacgaa attagaagaa
    21901 gtttctgtag ggaaagatac gatgacaggc cactgggaaa tcatgggatt gaatatcaaa
    21961 actccatttc gtgtgtttcc taatggattc cctgatgatc tgatcaaaca aatcgaagaa
    22021 ttttctggcc gtaaagtcgt atgtaacaaa ccttatagcg gaacagctgt tattgacgat
    22081 tacggtgaac accaaatgaa aacaggcgat ttaattgtat atacttctgc cgatcctgtc
    22141 cttcagatcg cggcacatga agaaatcatt cctttagaag aattatatcg gatttgccaa
    22201 ttcgttcgtg atataacaaa agatgatccg tatatgattg gccgaatcat tgcacgtccg
    22261 tacgtgggtg aaccaggaga cttcacacga acaagcaatc gccatgatta tgcgttgaat
    22321 ccattcggac acacagtcct tgattctttg aaagaagcag gaaaggacgt gattgctgtt
    22381 ggaaagatca acgatatttt caacggacaa ggaatcactg aatctgtccg cacgaaaagc
    22441 aatatggatg gcgttgacca gctgctgaaa gttatgaaaa acgatttttc aggaatcagc
    22501 tttaccaatt tagtagattt tgatgcatta tacggtcatc gtcgggatgt agtcggctat
    22561 gcgcatgcga ttgaagaatt tgacttacga attccagaat tgcttgaagc gatggaagaa
    22621 gacgacttgc taatgattac agccgatcac ggaaacgatc cgacgtttac tggtaccgat
    22681 catacgcgag aatatgtacc gttattggtt tacagtaaaa aaatgaaaga acaaggggca
    22741 ttgcctcaag gatattattc agatatttca gcaacgattg ctgagaactt tagtgtttct
    22801 tcgactgaaa atggcgaaag cttcttgaaa ttattaaaat aatcttttta aataggagaa
    22861 agcaaatgac caagttaagc gagatgttac aagaaacgac ccagtttatc cttgataaag
    22921 gagtaaaaga aattgatttt ggtttgattc taggttcagg attaggtgaa ttagcagatg
    22981 aaatcgaaga tgctgtaatg atttcttatg atgagatccc gttctttcct gtttcgacag
    23041 tagttgggca tgcaggaaag ctagtttatg ggtctctggc aggcaagaaa gtgttagcca
    23101 tgcaagggag attccactac tatgaaggtc attccatgca aacagtgacc tatccagtac
    23161 gtgtgatggc cggactaggg gcccattcag tcattgtgac taatgcatgt ggtggtgtca
    23221 acgaatcatt tgtaccagga gatttgatgc tgattaccga tcatatcaat tttactggtg
    23281 aaaatccttt gatcggtccg aatgaagatg caatgggccc tagatttcca gatatgagtc
    23341 aagcttatac gcctgactat caagcaacag caaaagcagc agcagaaaaa ctaggtttgg
    23401 atcttaaaga aggcgtatat atgggctatt ctggaccaac ttatgaaacg cctgcggaga
    23461 tccgaatgtc tcggacaata ggagccgatg cagtagggat gtcgactgtt ccagaagtca
    23521 tcgtagcagc tcacagcgga ttaaaagtgt taggaatctc ttgtattacc aacttagcag
    23581 caggtatgca agcgaatctg agccatgaag aagttgtaga aacaactcag agagtcaaac
    23641 aatcttttaa agcattggtt aaagaaacat tgacattatt gtaataggag gaacaataaa
    23701 atgagtgtgc atattgaagc gaaagaaggc gagatcgccg ataagatttt acttccggga
    23761 gatcctttgc gagctaaata tattgcggag acttttttgg aagatccagt ttgttacaat
    23821 caggtacgcg gtatgttagg ctttaccggc aaatataaag gagaacgtat ttctgttcaa
    23881 ggaacaggaa tgggaatgcc atcagccacc atctatgccc atgaattgat ccagtcgtat
    23941 ggtgtaaaga aattgattcg agtaggtaca tgcggtgcat tgtcaaaaga cgtccatgtt
    24001 cgtgatttag tactagcaca aggtgcagcg accagttctt cgatgatcga aaaaaatttc
    24061 caagcctttc attttcctcc aatcagtgat ttcaatctat tactgaaagc atatgagata
    24121 gctaaagaaa agggctatac ggttcatgta ggaaatgttc tttcggaaga ttctttctac
    24181 aaagatgatt tgacagagac gttccaatta gctgaacttg gcgttttagg agtggaaatg
    24241 gaagcagcgg ctctttatta cttaggcgcg aaataccatg tgcagacatt aagtttgatg
    24301 accgttagcg accatttgat caccggtgaa gaaacaacag ctgcagaacg tcaatctacg
    24361 ttcaatgaaa tgatcgaagt aggattggaa acagcgatag cagaataaga aggaaatgaa
    24421 aaagctgccc tgcattaagt aataagaaca tccaagcaaa aatagctcct catgtttttg
    24481 acttggctgg acttattatt gcaaatgtaa gcttttgaac accgtttacc aagaggttgt
    24541 gaatctgccg tttaactctg agtcacaagg aacaatttca aaaaacagct tttcatgttt
    24601 gatgaatatt gtgacttgtg accgagaagt tggcaggaga aaaccgttta tacgaaaaaa
    24661 gggactgtga caaatcgtgt cacagtccct tttttatagt gttttttata ggtagtattt
    24721 tttagcaact gttaagtcat catttaattc ataaacaagt ggttgacctg ttggaatttc
    24781 aagatccatg atgtcttcgt cagagatacc ttcgatatgt ttagctaggg cgcgtaatga
    24841 gttaccatgt gcagctacta aaacagtttt gttgtctagt aatgctggag caatttcatc
    24901 ttgccagaat ggcaaagcgc gttctaatgt cactttcaag ttttctccac caggaatatc
    24961 gcgtttgtct aacattgcgt aacgacggtc atttgctgca gaaccttcgt cagtttcttc
    25021 cattaatgga ggaagagtat cgtaagaacg acgccagatg tgcacttgtt cgtcgccgta
    25081 tttttcagct gtttcttttt tgttcaaacc ttgtaattta ccatagtgac gttcgtttaa
    25141 gcgccatgat ttgatttgtg gtacccaaag ttgatctgaa tattctaaga tcaagttaca
    25201 tgttttgatt gcacgagtta aaacagaagt gtaagcaaca tcaaattcga ttccagcttc
    25261 tttgattttg cgtccgcctt cttttgcttc ttcgattcct tctggtgcta gatttacatc
    25321 agcccaacca gtaaattggt tcaatgcatt ccattcacta agaccgtgac gagaaaaaac
    25381 taattttggc atgtttagct ctccttttaa gataggttta tatttctgaa attttcagtt
    25441 ctgttttatt gtacaatttt ttggaagaga tttccatcga aaaattagat aagattctat
    25501 gagaaaacaa gtagagaata taaaaaaacg aacagtgccc acgcaactgt tcgtttttag
    25561 gtattagatg cataattgct cgatttcttt ttcaggtaaa ttgatatatt tataacatgt
    25621 tccaactgaa acaccgcatt ttgaagaaat aaattggatc gtttcttttt tttcataata
    25681 gagacgtcgg atttttttga tcgtttttgc atcgattttt ggtcttccgc cgatttttcc
    25741 ttttttacga gcttcatcta atccaactaa tgtacgttct ttgatcaatg cgcactccat
    25801 gtttgctagg ttttccatta attggaaata gatttttccc atttcgcgcg tatcgattcc
    25861 ttcatcaaga ctaatcaagt gcagcccgcg atctttgaat aattgcgtga gttctgttaa
    25921 ttgccgcgta gatttgccta atcgatgaag ttggcaaatg actagtgcat cgccttgttg
    25981 catgtcagcg atcactgact ccaaatgaac agcagtagaa tcattttgtt ccacttcata
    26041 tgtctcatgg aaaatttctt gacaaccaaa gtcagataat tgatcaacct gagttgttaa
    26101 atcaacgtca tttatggttg tgcgtgcata accaataatt ttcatggtga ttcctttcta
    26161 gcagtgattt tctaactgga tataacagta aaaatgtagc ataaagtacg tcaaaaagat
    26221 agttttttcg caaattttcc gctgtctttt tttattggat gatcaagcag tttttcttta
    26281 tttacgacgg attgcgtcaa gaatctcaac gcctttttct gagccgacaa ctactttaga
    26341 aaccatgttt aggaaaagcc catgttctac taccccaaca agttcatcta aataggtagc
    26401 taagctttct ggctgttcga tgacttctag atgcagatca atgatgtaat gaccaccatc
    26461 tgtggttaag acttctccgt tttcgtctgt acgcaagacg ggttggaatc ttttttcttc
    26521 aaaaatatga agtagctgtt gggagccata agggatcact tcaactggga gtgggaactt
    26581 cccaagttta tcgactaatt tagaagaatc aacgatccaa atcgtttctt ttgagtacgt
    26641 agcgactatt ttctcgaaaa gcaaagcagc gccgccgcct ttgatccctt gaaaatcagc
    26701 actgatttca tcagcaccgt ctattgtcaa atcgactacg gggacttcat caatactctt
    26761 taacggtatt cctaattttt ccgcttgttc ttttgtcgca tttgaagtag taactcctgt
    26821 gatacgtaaa ccttcttcac gcatacggcg accaatctct tctaccatat aataggcggt
    26881 tgaaccggtc ccgagaccta cgatcatccc gtcctttacg aatttcgcgg cttcaatgcc
    26941 agctaattgt tttaaattca tctttgcgtc cacctttttt tagtttgagc atcgtgcttt
    27001 cctcactatt ttagcgtgat ttacggtaaa aagataccat tcttttttat tccaataaag
    27061 ctttttcaaa aaaaattgca tctcttgttg acatgttttt tcattcgtga tattctaaca
    27121 aaggtgcttt atctacaggt ttctgtgaag aaacgtgctg actgtttatc aaagcatatt
    27181 tgataaggat gcagacattg catttatttt ttatcacaaa aaaagaacca cctggatgtg
    27241 tggaactaga cgcaaatcgt gggaaggagg aaacaaggaa tgcctacaat taaccaatta
    27301 gtacgtaaac ctcgtaaatc aaaggtggaa aaatctaatt cacctgcttt gaacaaagga
    27361 tataacagct ttaagaaaac tcaaactaac gtaaactcac ctcaaaaacg tggggtagca
    27421 actcgtgtgg gtacaatgac acctaaaaaa ccgaactcag ctttacgtaa atatgcacgt
    27481 gttcgtttgt caaacttaat tgaagttact gcttatatcc cagggattgg tcataactta
    27541 caagaacaca gtgttgtatt attacgcggt ggtcgtgtaa aagacttacc aggggtacgt
    27601 taccatatcg ttcgcggtgc tttagatact gctggtgtta acgaccgtaa acaaagccgt
    27661 tctaaatacg gaactaaaaa acctaaagct taattttaat tattaaacaa atgaaacttg
    27721 cttctactat atagaagtaa ttactatgaa caatatttcg gaaggaggag ttacggatgc
    27781 cacgtaaagg tcctgttgca aaacgtgatg ttttaccaga tcctatttat aactcaaaat
    27841 tagtaactcg cttgatcaac cgtgtaatgg ttgacggaaa acgcgggatt gcagctaaca
    27901 ttatctataa tgcctttgac ttgatcaaag aatctacagg taacgatcca ttagaagtgt
    27961 ttgaacaagc aatgaaaaac gttcaacctg ttcttgaagt taaagcacgt cgtgttgggg
    28021 gttcaaacta ccaagtacca gttgaagttc gccctgaacg ccgcgttact ctaggtcttc
    28081 gttgggtagt aaactacgct cgcttgcgcg gtgaacacac aatggaagaa cgcttagcaa
    28141 aagaaatcat ggatgctgca aacaacacag gtgcttctgt taaaaaacgt gaagacactc
    28201 ataaaatggc tgatgccaac cgtgcgtttg ctcactatcg ctggtaagat tctctctgtt
    28261 tggtcggctt ttataagtcg acctcagata gtgtccttat ttttagcaac tagatagtaa
    28321 agagaggaga aacaaggaga atgaccagag aattttcttt acaaaacact cgtaatatcg
    28381 gtatcatggc ccacatcgat gctggtaaaa cgactgctac tgaacgtatc ttgtactata
    28441 ctggtaaaat ccataaaatt ggtgaaactc atgaaggagc ttcacaaatg gactggatgg
    28501 aacaagaaca agaacgtggt attacgatca cttctgctgc tactacagca caatggaagg
    28561 gtcaccgaat caacatcatc gacacaccag gacacgtaga cttcacagtt gaagttgaac
    28621 gttcattgcg tgtacttgat ggtgctgtaa ctgttcttga tgcacaatca ggtgttgaac
    28681 ctcaaactga aacagtttgg cgtcaagcaa caacttatgg tgtacctcgt atcgtatttg
    28741 caaacaaaat ggacaagatc ggtgctgact tcttatattc agtatcaact ttacatgacc
    28801 gtttgcaagc aaacgctcac ccaatccaat taccaattgg tgcggaagac gacttcacag
    28861 gaattatcga ccttgtaaca atgaaggctg aaatgtatac aaacgatctt ggaacagaga
    28921 tcgaagaaac agaaattcct gaagaatacc gcgaattagc tgaagaatgg cgcgaaaaat
    28981 tggttgaagc tgtagctgaa actgatgaag aacttacttt gaaatactta gaaggtgaag
    29041 aaatcactga agctgagtta aaagaaggta tccgccgcgc aacagttaac gtagaattct
    29101 acccagtact atgtggttca gcatttaaga acaaaggggt tcaattacta ttggacgctg
    29161 ttcttgatta cttgccatca ccgttagata tcccagctat caaagggatt gaccctaaaa
    29221 ctgatgaaga agtagaacgt cctgcagacg acagcgctcc tttctcagct ttagcattta
    29281 aagttatgac tgacccattc gtaggtcgtt taactttctt ccgtgtgtac tctggtgttt
    29341 tacaatcagg ttcatacgta caaaacgcaa caaaaggcaa acgtgaacgt gttggtcgta
    29401 tcctacagat gcatgccaac tctcgttcag aaatctctga agtttacgct ggagatatcg
    29461 ctgctgctgt tggtttgaaa gacacaacta ctggggacac actatgtgat gaaaagagtc
    29521 tagttattct tgaatccatg gaattcccag aaccagttat ccaagtcgct attgaaccta
    29581 aatcaaaagc tgaccaagat aaaatgggtg tggctttaca aaaactatct gaagaagatc
    29641 ctactttccg tgctgaaaca aacgtggaaa caggcgaaac aatcatcgct ggtatgggtg
    29701 aacttcactt agatatcatc gttgaccgta tgcgtcgtga attcaaagtt gaagctaacg
    29761 taggtgcgcc tcaagtatct taccgtgaaa ctttccgtgc tggcactcaa gccgaaggta
    29821 agtttgtacg tcagtctggt ggtaaaggtc aatacggtca cgtatggatt gaatttacac
    29881 caaatgaaga aggtgctggt ttcgaatttg aaaatgcgat cgtcggtggg gttgttcctc
    29941 gtgaatacat tccagctgtt gaaactggtt tgaaagatgc tatggaaaat ggtgtcttag
    30001 ctggctatcc attagtagat atcaaagcta aactttacga tggttcatac catgatgtcg
    30061 attcaaatga aactgccttc cgtgttgctg cttctatggc attacgtgca gcagctaaga
    30121 aagctaatcc agtaatcctt gaaccaatca tggctgtaga agttgttatc cctgaagatt
    30181 atttaggtga tgttatgggt cacgtaactg ctcgtcgtgg acgtgttgaa ggtatggaag
    30241 ctcgcgctgg cggccaacaa gttgttcgtg cgatggttcc acttgctgaa atgtttggtt
    30301 atgctacaac tcttcgttct gctactcaag gtcgtggtac atttacaatg acatttgacc
    30361 actacgaaga tgtaccaaaa tcagtacaag aagaaatcat taagaaaaac ggcggaaaag
    30421 ctgaataatt tcttaaaacc ggatagtcct gcaaagagat tatccaaaga gactatattt
    30481 ttaatatagt ttcgtgtaaa ataattatcg atgatatggg catgtggtgt accttgtgta
    30541 catcatatac ctatcagaca aataaaaaat atattgtatt tttaggagga cattttaaaa
    30601 tggcaaaaga aaaatttgac cgttctaaac cacacgttaa cattggtact atcggacacg
    30661 ttgaccatgg taaaactaca ttaacagctg caatcacaac tgtactatct aagaaaaacg
    30721 gcggccaagc tatggcttac gatcaaatcg atggtgctcc agaagaacgc gaacgcggaa
    30781 tcacaatctc aacagctcac gttgagtatg aaacagatac acgccactac gctcacgttg
    30841 actgcccagg acacgcggat tacgttaaaa acatgatcac tggtgctgct caaatggacg
    30901 gagctatctt ggtagtttct gctgctgacg gcccaatgcc tcaaactcgt gaacacatcc
    30961 tattgtctcg tcaagttggt gttccttaca tcgttgtatt cttgaacaaa gtagacatgg
    31021 ttgatgacga agaattacta gaattagttg aaatggaagt tcgtgaccta ttaacagaat
    31081 acgaattccc tggtgacgat gttcctgtag ttgctggatc agctttgaaa gctctagaag
    31141 gcgacgcttc atacgaagaa aaaattcttg aattaatggc tgcagttgac gaatacatcc
    31201 caactccaga acgtgacaac gacaaaccat tcatgatgcc agttgaagac gtgttctcaa
    31261 ttactggacg tggtactgtt gctacaggtc gtgttgaacg tggacaagtt cgcgttggtg
    31321 acgaagttga agttgttggt attgctgaag aaacttcaaa aacaacagtt actggtgttg
    31381 aaatgttccg taaattgtta gactacgctg aagctggaga caacattggt gctttactac
    31441 gtggtgttgc acgtgaagac atccaacgtg gacaagtttt agctaaacca ggtacaatca
    31501 cacctcatac aaaattctct gcagaagtat acgtgttgac aaaagaagaa ggtggacgtc
    31561 atactccatt cttcactaac taccgtccac aattctactt ccgtacaact gacgtaacag
    31621 gtgttgttga attaccagaa ggaactgaaa tggttatgcc tggcgacaac gtaacaatgg
    31681 aagttgaatt aatccaccca atcgctatcg aaaacggtac taaattctca atccgtgaag
    31741 gcggacgtac agttggtgcc ggtgtcgtta cagaaatcaa agcttaattc acttaagttt
    31801 taaagtaaag caacatttat tcggacgtaa tcgctcggaa cgaaggtctt aggatctttg
    31861 ttccgagctt ttttatttat tgcaggatca ggaaaaaaga caggagtatt ataaatagaa
    31921 gaaacacgaa ataaaagagt cagtattttc taaatgaaac tttatgaaaa caaaatgttt
    31981 tttacaagaa aaagccttgc tttgtgagtt tatatatatt ataatgacaa aggtgcgttt
    32041 actttagtga attgcacaga cgtaatcaga atgatttcgt cggctaagaa acgagaggtt
    32101 gcgacacgcc cggacgcttt gccacgaacg agcgtgacgg aaattttcgt ggagctatgt
    32161 ctacttttca aaataggcga aggagggaac aagatggcaa aacaaaaaat tcgtatccgt
    32221 ttaaaagcgt atgaacaccg tattttagat caatcagcgg ataaaatcgt ggaaactgca
    32281 aaaagaactg gagctagcgt gtctggtcca attccattac caactgaacg cagtctttac
    32341 acaatcatcc gtgcgactca taaatacaaa gattcacgcg aacaattcga aatgcgtaca
    32401 cacaaacgtc ttatcgacat tgtgaaccca acaccaaaaa ctgttgatgc tttgatgaag
    32461 ctagacttac catctggtgt aaacatcgaa atcaaattat aaaactaaaa caaaaataat
    32521 ggaggtgtac tcatgaccaa aggaatctta gggaaaaaag tgggaatgac acaaatcttc
    32581 actgaatctg gtgaattaat tccagtaact gttgtagaag ctactccaaa cgtagtacta
    32641 caagtgaaaa caatggaaac ggatggctac gaagctattc aagttggtta ccaagatatg
    32701 cgtgaagttt tatcaaacaa acctgcgaaa ggtcatgttg caaaagcaaa cacggctcct
    32761 aagcgcttca ttcgtgaatt caaaaatgtt gagctaggag aatatgaagt aggaaaagaa
    32821 attacagtag atgttttcca agcaggagac attattgatg taacaggtac tacgaaaggt
    32881 aaaggattcc aaggggttat caaacgccac ggacaaagcc gcggaccaat ggctcacggt
    32941 tctcgttacc atcgtcgtcc tgggtcaatg ggtccagttg cacctaaccg tgtatttaaa
    33001 aacaaacgtc ttgctggccg tatgggtggc aaccgcgtaa ctatccaaaa cttggaagtt
    33061 gtacgtgtcg atgcagaaag aaatgttatc ttgatcaaag gtaatgttcc tggagctaaa
    33121 aaatctttaa ttactatcaa atcagctgtg aaagctaaat aattgtagga agaaaggagg
    33181 aactaaggaa tgccgaatgt agcattattc aaacaagatg gaagccaaaa cggtgaaatc
    33241 acacttaacg aagaaatctt cggaattgaa cctaatgaaa gtgttgttta cgatgcaatc
    33301 gtaatgcaac gtgcgtcatt aagacaagga acacacgcgg ttaaaaaccg tagcgctgtt
    33361 cgcggcggcg gacgtaaacc atggcgtcaa aaaggaacag gtcgtgcacg tcaaggatct
    33421 atccgctcac cacaatggcg tggaggtggc gtagtctttg gaccaacacc acgttcttac
    33481 agctacaaac ttcctaaaaa agttcgtcgt ttagcaatga aatctgtatt gtcagaaaaa
    33541 gttgctgaaa acaacttggt agcaatcgaa ggcttgaact tcgacgcacc aaaaacaaaa
    33601 gaattcaaac aagttcttgc taacttatct atcgactcta aagtattggt tgttctagaa
    33661 aaaggtaacg actttgctgc tttatcagca cgtaacttac caaacgtttc tgtagtaact
    33721 tctgataatg tgagtgtgct agacgttgta tcaaatacaa aagtgttagc aacacaaact
    33781 gctcttactc aaattgagga ggtgcttgca taatgaactt actagacgta atcaaacgcc
    33841 cagtgatcac tgaaaaatca atgcttgcca tggatgacaa gaaatacact tttgaagtgg
    33901 acactcgcgc aaacaaaact ttagtaaaac aagcggtaga agctgctttt gacgttaaag
    33961 tcaaaaacgt gaacatcgtg aacgtacgtg cgaaattcaa acgtatgggc aaatatgcag
    34021 gatatacaaa aaaacgtcgc aaagcgatcg ttacattgac tgaagattca aaagaaatcc
    34081 aattattcga agctgctgaa taagcactaa tagataactc attaaattag gagggaaaaa
    34141 cgtggcgatt aaaaagtaca aacctacctc aaatggtcgt cgtaacatga caggttctga
    34201 ttttgctgaa atcacaacat caacacctga aaaatcattg ttacaaccat tgaaaaacca
    34261 tgctggacgt aacaacaacg gccgcatcac tgtacgtcat caaggtggcg gacacaaacg
    34321 ccaatatcgc gtgatcgact tcaaacgtaa caaagataac gttgttgcaa ctgttcaaac
    34381 gatcgaatat gatccaaacc gttcagctaa catcgcgtta gtacactatg aagatggagt
    34441 gaaagcttac atcttagcac ctaaaggact agaagtgggt atgaaacttg tttcaggtcc
    34501 agaagcagat atcaaagtcg gaaatgctct tccattagaa aacattccag ttggtactgt
    34561 tatccacaac attgaaatga aacctggtaa aggtggacaa ttgatccgtt ctgctggtac
    34621 aagtgctcaa gtacttggta aagaaggcaa atacgtattg atccgcttga actctggtga
    34681 agttcgtatg atcttagctg catgccgtgc tacaatcggt tctgtaggta acgaacaaca
    34741 cgaattaatc aacatcggta aagctggacg ctctcgttgg atgcgtaaac gcccaactgt
    34801 acgtggtagc gtaatgaacc ctaatgatca cccacacggt ggtggtgaag gtaaagctcc
    34861 tatcggacgt aaagcaccag tttctccttg gggtcaacca gctcttggtt acaaaactcg
    34921 taacaaaaaa gctaaatcag acaaacttat tgttcgtcgt cgcaaaaata aataattact
    34981 ttgaccatgt gtcgcacatt ttgagaggag gttcaccatg ggtcgtagtt taaagaaagg
    35041 accttttgtc gatgagcatt taatgaaaaa agttgaagct caagcagggg ttgaaaagaa
    35101 aaaagttatc aaaacttggt cacgccgttc aacagttttc ccaagttttg ttggatatac
    35161 catcgcagtt tatgatggac gtaaacatgt accagtttac atccaagaag acatggtagg
    35221 acacaaatta ggtgaatttg cacctacaag aacttatcgt ggacatgctg ctgacgataa
    35281 gaaaacgaaa cgctaatttg aggggaggat aaatccaaat ggcagaacaa atcacatcag
    35341 ctaaagcaac tgcaaaaaca gttcgcactt cacctcgaaa agcccgttta gtaattgacc
    35401 ttatcagagg taaaagtgtc gcagatgcaa tttcaatctt gaaattcaca ccaaacaaat
    35461 ctgctggaat cattgaaaaa gtattgatgt cagcagttgc gaatgcagaa aataactttg
    35521 acttagatgt tgaaaacttg gtagtaagcg aagcttttgt taacgaagga cctacaatga
    35581 aacgtttccg tcctcgtgca aaaggatcag cttctccaat caacaaacgt acaagtcata
    35641 tcacggtagt cgtatcagaa aaataaggag ggataatcag tgggtcaaaa agtacatcca
    35701 attggaatgc gtgtaggcat catccgcgac tgggatgcta aatggtatgc tgaaaaagag
    35761 tatgctgagt tcttacacga agatttaaga atccgtaaat ttatttcaac taaacttgct
    35821 gatgctgctg tatcaacagt tgaaatcgaa cgcgcaacag gtcgcgtaaa catttcaatt
    35881 cacacagcta aaccaggtat ggttattggt aaaggcggtt ctgaagtcga aagcctaaga
    35941 aaagaattaa acaaattaac tggtaaaaga atccatatca atatcgtgga aatcaaaaaa
    36001 ccagatctag atgcaaaatt agtaggtgaa ggaatcgcac gtcaattaga aaaccgtgtt
    36061 gctttccgtc gcgctcaaaa acaagccatc caacgctcaa tgcgtgctgg cgctcaaggg
    36121 atcaaaactc aagtatctgg tcgtctaaac ggagcagata tcgctcgttc agaaggatac
    36181 tcagaaggaa ctgttcctct tcatacttta cgtgcggaca ttgattacgc atgggaagaa
    36241 gcagatacaa catacggaaa actaggagtt aaagtgtgga tctatcgtgg agaaattctt
    36301 ccaactaaaa aaaacactga gaaaggaggg aaataatcat gttagtacct aaacgtgtaa
    36361 aacaccgtcg tgaattccgc ggaaaaatgc gcggggaagc taaaggcgga aaagaagtag
    36421 cattcggtga atacggtttg caagctgttg attcacattg gatcacaaac cgccaaatcg
    36481 aagctgctcg tatcgcaatg actcgttaca tgaaacgtgg tgggaaagta tggattaaaa
    36541 ttttccctca caaatcttat actgccaaag caattggggt acgtatgggt tctggtaaag
    36601 gggcacctga aggatgggtt gcaccagtaa aacgtggtaa aatcatgttt gaaatcgcag
    36661 gcgttcctga agaagtagct cgtgaagcgt tacgtctagc ttctcacaaa ttaccaatga
    36721 aaactaagat cgtaaaacgt gaggaaatgg gtggtgaatc gaatgaaggt taaagaaatc
    36781 agagaattaa ccactgccga aatgcttgat caagaaaaac aattaaaaga agaattgttt
    36841 aatcttagat tccaattagc aacaggtcaa ttagaaaaca ctgcacgtat taaagaagta
    36901 cgtaaatcga ttgcacgcat caaaactgtg ttgcgtgaac aagctaagta attatggaag
    36961 gaggccatta agcgtatgac tgaaggaaga aatcaacgca aagtttatca aggtcgcgtg
    37021 gtttcagaca aaatggataa aacaattacc gttgctgtcg aaacaaagaa aaaccaccct
    37081 atctatggca aacgcatgaa ctattctaag aaatacaaag tgcatgatga aaacaacaca
    37141 gcaaaagttg gcgacatcgt gagaattatg gaaactcgtc cattatcagc tacaaaacgt
    37201 ttccgtttgt tggaagtagt cgaagaagca gttattatct aataacacga gattttccta
    37261 tatagattga atgcaaaatc tgaaaggagg atacacaacg tgatccaagc agaaagtcgt
    37321 ttaaaagtcg ctgataactc aggcgcacgt gaaattttga cgatcaaagt ccttggtgga
    37381 tctggtcgta aaactgctaa catcggtgat gtgatcgttg ctacggttaa acaagcaacg
    37441 ccaggtgggg ttgtcaaaaa aggtgacgtc gttaaagccg ttatcgttcg aacaaaatca
    37501 ggagctcgtc gtacagacgg ttcatatatt aaatttgatg aaaatgctgc agtgattatt
    37561 cgtgatgata aaagccctcg tggaacacgt atctttgggc cagttgcacg tgaactacgt
    37621 gaaaacaact tcatgaagat cgtttcacta gcaccagaag ttttataatc ttgagacact
    37681 tatcaaagga ggtgcgaaac agttatgttt gttaaaaaag gcgataaagt taaagttatc
    37741 actggaaaag acaaaaacaa agaaggcgtt gtactagcag cgttcccgaa aaaagataaa
    37801 gttattgtcg aaggtgtaaa tgtcgttaaa aaacaccaaa aaccttctca agctgctcct
    37861 caaggtggaa ttgttgagat ggaagcgcca attcatgttt ctaacgtgat ggtggttgac
    37921 tctactggtg tagctggccg agttggctac aaagaagtag acggcaaaaa agtccgtgtt
    37981 tctaaaaaaa ccggtgaagt tttagataaa taaaagttta aggaaggagg gtcttactga
    38041 atgaaccgcc taaaagaaaa atatcttaaa gaagtaactc catcattgat ggaaaaattt
    38101 aactatagct ctgttatgca aacacctaaa gttgaaaaaa tcgtcatcaa catgggtgtt
    38161 ggtgatgcgg tatcaaacgc taaaaactta gataaagcag ttgaagaatt aactttgatc
    38221 actggtcaaa aaccaatgat tacaaaagct aaaaaatcaa tcgctggatt ccgtttacgt
    38281 gaaggaatgc caattggtgc aaaagttaca ttgcgcggag aaagaatgta cgaattctta
    38341 gacaaattgg tttctgtttc actaccacgt gtacgtgact tccatggtgt aagtaaaaaa
    38401 gcctttgacg gtcgtggaaa ctatacttta ggtattaaag aacaattgat cttcccagaa
    38461 gtagattatg atttagtaga taaagtacgt ggtatggaca tcgttattgt aacaacagca
    38521 aactctgatg aagaatctcg tgagttgttg acacaattag gcatgccatt ccaaaaataa
    38581 ttaaaggagg cgaactacgt ggctaaaaaa tcaatgattg ctaaaaacaa acgtcctgca
    38641 aaattttcaa cacaagctta tactcgttgc gaacgttgcg gacgtccaca ttcagtttat
    38701 cgtaagttcc atctttgccg tatttgcttc cgcgaacttg cctataaagg tcaaattccc
    38761 ggcgtgaaga aagctagctg gtaaaaagta aattcgcata agaaggaggt aaaagatcaa
    38821 tggtcatgac agatccaatt gcagattttc taactcgtat ccgtaacgca aacatggtta
    38881 aacatgagtc tttagaagta cctgcatcaa aaattaaacg tgacatcgct gaaatcttga
    38941 aacgtgaagg tttcgttcgt gatgttgaat acatcgaaga tgacaaacaa ggcgtgatcc
    39001 gtgttttcct aaaatttggt aaaaacggcg aacgtgttat cacaaactta aaacgtatct
    39061 ctaaaccagg tttgcgtgct tatgtcaaag ctgacgaagt accaaaagta ttgaacggtt
    39121 taggtatcgc aatcatttcg acttctgaag gtgttgtcac tgataaagaa gctcgtgaaa
    39181 aaaatatcgg cggcgaagtt atcgcttacg tatggtaatc aagtagaatc tacaaggagg
    39241 tgtctttaag tgagccgtat cggaaataaa gtcgttgtta tccctgaagg agtaacagtt
    39301 actcaagacg gaaacaacgt tacagttaaa ggaccaaaag gtgaattgac tcgtactttt
    39361 tcagcagata tcaaaatgaa tatcgaagga aacgaagtaa ctttcactcg tccaaacgac
    39421 agtaaagaaa tgaaaacaat tcatggaaca actcgtgcga acttcaacaa catggttgta
    39481 ggtgtcagcg aaggtttcca aaaagcgtta gaactaatcg gggttgggta ccgtgcacaa
    39541 ttacaaggat caaaacttgt attgaacgtt ggttactcac atccagtaga aatcacacca
    39601 ccagctggag taactgttga agtaccagct aacacacaag taattgttaa aggtgcgaac
    39661 aaagaagaag ttggcgaatt agctgcaaac attcgtggaa ctcgtcctcc agaaccttat
    39721 aaaggtaaag gtattcgtta tgttggcgaa tatgtacgcc gtaaagaagg taaaactggt
    39781 aaataatcgt ttagaaaaat tgcatagaag ccagcagcag gaaaaaggca tttggctgaa
    39841 gtttaccttc aaaaaaatac atttttactt gtgccgcagc ttctattttt cgaaacgtat
    39901 ttactgcttg aaatagtagt acaataaaaa taaagaggtg acaattgtga ttacaaaacc
    39961 agataagaac aaaacacgtc aaaagagaca tcgtcgtgta cgtaacaata tctctggtac
    40021 tgctgagcgc ccacgcttga acgtttttcg ttctaacaaa aacatctacg ctcaaattat
    40081 tgatgacgta gcgggtgtaa cgctagcaag tgcctctacc ttggataaag aaatttcagg
    40141 tggaacaaaa acagaagcag cacaagctgt cggtaaacta gttgctgaac gtgcagctga
    40201 aaaaggcatt aaagtagtag tctttgaccg tggtggatac ctttaccatg gccgtgtgca
    40261 agctttagct gaagctgctc gcgaaaatgg actagaattt tagaagaagg aggaatacca
    40321 ttcatggttt atatcgatcc aaaacatttg gaattagaag accgcgttgt tgcaattaac
    40381 cgtgtaacaa aagttgttaa aggtggacgt cgtctacgtt ttgctgcttt agttgttgtc
    40441 ggtgacaaaa acggacacgt agggtttggt acaggtaaag ctcaagaagt tcctgaagca
    40501 atccgtaaag caattgaaga tgcgaagaaa aacttagttg aagtacctat ggttggttca
    40561 acaatcccac acgaagtaat cggtgctttt agtggtggta gaatcctaat gaaacctgct
    40621 gtagaaggtt ctggggttgc tgctggtgga ccagttcgtg ccgtattaga attagctggg
    40681 gtagcagata tcacttctaa atctttaggc tcaaatacac caatcaacgt tgttcgcgca
    40741 acagttgaag gtttgaaaca attgaaacgt gcagaagaag ttgcagaact tcgcggcaaa
    40801 tcagttgaag aattaatcgg ataaggagga caacaataat ggctgaatta aaagttactt
    40861 taaaacgcag tattatcgga cgtcctcaaa accaacgcga tacagttaaa gcgttaggtc
    40921 ttacaaagat taacagttca gtggttaagc cttctaatga agcaattaaa ggcatgatca
    40981 atactgtttc tcacctagtg gacgttgaag aaatttaatt tagaaaaatc ataactagaa
    41041 cattaaggag gtgccaaacc tatgaaactt catgaattaa aacctgctga aggttcacgc
    41101 caagtacgta accgtgttgg tcgtggtact tcatctggta acggaaaaac tgccggacgc
    41161 ggacaaaaag gacaaaaagc tcgttcaggc ggcggtgtgc gtttaggatt tgaaggggga
    41221 caaacaccat tgttccgtcg tttaccaaaa cgaggattca caaacgtgaa ccgtaaagac
    41281 tatgcagtca ttaatcttga tgtattgaac cgctttgaag acggagctga agtaactcct
    41341 gttgctttag ttgaagctgg aatcgtgaaa aacgaaaaag ctggaatcaa agtattagct
    41401 aatggggaac taaacaagaa attaactgtg aaagcagcaa aattctctaa agcagctcaa
    41461 gaagcaattg aagcggctgg tggatcaatc gaggtgatct aatgtttaga ctattaaaag
    41521 atgcttttaa agtaaaagac attagatcga aaatcctatt tactgtattt gtgttgtttg
    41581 tatttcgcct aggtgcacat attactgtac caggcgtaaa tgctgcttca ttgcaaaacc
    41641 tttcttcttt gccatttttc aacatgttga acttggtaag tggtagtgcg atgcaaaact
    41701 tttccatttt ctcaatgggg gtttcaccat acattactgc ttctatcgtc attcagcttc
    41761 ttcaaatgga catcgtgcct cgatttgttg aatggtcgaa acaaggggaa gttggtcgta
    41821 aaaaactgaa tcaagcgact cgatatctga cattagtatt ggcatttatc caatctgtcg
    41881 gtatcactgc tggattcaat caatacgctc aattaggttt cgtgaataat cctaacgtag
    41941 caacttacgt aacgatcggt ttgattctaa cagccggtac gatgtttgtt acttggctag
    42001 gagaacagat cacagaaaaa ggtatcggaa atggcgtatc aatgatcatt tttgcaggta
    42061 tcatttctag attgcctgaa agtatcagag aaatttatga agattacttt ataaatattg
    42121 atccttcaga catatggaaa tctgctattt ttgtggccat tttactagta gcggtcttgt
    42181 tgatcgtgac attcgtaaca tttttccaac aagctgaacg caagatcccg atccaatata
    42241 cgaaacgcgt agctggcgcg cctacaagca gctatctgcc gttgaaagta aatgcagctg
    42301 gagttattcc agttatcttt gctagttcgt ttattgctac gccaaatgct gttttacaag
    42361 cattgagcgg tagattcggt tctgaaaact ggtacaaagt gatgatggag atctttaact
    42421 ataatacagc acctggtgct acgatttata cgattctgat cgttgccttc actttcttct
    42481 acgcctttgt tcaagtaaac cctgagaaat tagcggaaaa cttgcaaaag caaggaagtt
    42541 atataccaag cgtacgccct ggtaagggga ctgaagagta tgtctcaaga ttactgatgc
    42601 gtttaagtac agttggtgca gtcttccttg gtttagtggc attgcttcca atcattgctc
    42661 aaatggtttg ggatcttcca caatcaatcg gattaggcgg tacaagctta ctgatcgtta
    42721 tcggtgtagc tttagaaact gcgaaacagt tagaaggctt aatgctgaaa cgtaaatatg
    42781 ttggattcat tgagtaagaa agcgtgttga ggtttcccct caacacacgt tctcacacat
    42841 ttattaggag ggaaaacaat gaacctcatt ttaatggggc tgccaggcgc aggtaaagga
    42901 acacaagctg aaaaaatcat tgatgcttat ggtattccgc acatctcaac aggagatatg
    42961 ttccgcgcag cgatgcaaaa cgaaacagct cttggcctgg aagcaaagtc ttatatggat
    43021 aaaggtgcat tagttcctga tgaagtaaca aatggaatcg tgaaagagcg actagctgaa
    43081 ccagatacag agaaaggctt cttattagat ggctttccac gtacgctaga tcaagcaaaa
    43141 gctctggacg caatgctaaa agatttgaat aaaaaaattg atgctgtcat cgatatccat
    43201 gttggtgaag aaatcttggt cgaacgtcta gccggccgat ttatctgcag caattgtgga
    43261 gcaacttacc ataaaatttt caaccctaca aaagttgaag acacatgtga tcgttgcggt
    43321 gggcatgaat tctatcaaag agaagatgat aaacctgaga cggttaaaaa tcgtctggct
    43381 atcaacatca aaaatagtga accaatcttg gcttattata aagaacaagg tttgctaaac
    43441 actattgatg gtgctcgtga aatcgatgct gtatttgcag atgtacaaaa aatcattgaa
    43501 aaatagcacg attgcccgta gccgacttgc attatgcagt tactcttgtc aagttcaata
    43561 aattatgata gaatatgtca gtccgacttc tagagaatcc tctagatgat ccattttgag
    43621 aattttgagg tgggaactgc agtttccgcc attttatcgt gtgaaaatgc gaaacaagta
    43681 caaggaggta ctgtgcgtgg caaaagaaga tatgattgaa gtcgaaggta cagtcgtcga
    43741 aactttgccg aatgcaatgt ttaaagttga actagaaaac ggacaccaag ttcttgctac
    43801 tgtttcaggt aaaattcgta tgcattacat ccgtatctta cctggtgaca aagtaacggt
    43861 tgaattgtct ccatacgatc ttaaccgtgg ccgtattact tatcgcttta aataattgta
    43921 ctccgtaaaa ctacaggagg tattatcatg aaagtaagac catcagtaaa accaatgtgc
    43981 gaacattgta aagtaattcg tcgtaaagga cgcgttatgg tgatttgccc agcaaatcca
    44041 aaacataaac aacgtcaagg ataattggag gtgctataaa tatggctcgt attgcaggag
    44101 tagatattcc tcgtgataaa cgtgtagtag tttcacttac ttatatctat ggtattggta
    44161 acactactgc taaaaagatc ttagctgatg ctggtgtatc tgaagatgtt cgcgttcgtg
    44221 aattaacgaa tgaacaaaca gatgctatcc gtgcagaagt agataaatta aaagttgaag
    44281 gggatcttcg tcgtgaagtg aacttgaaca tcaaacgttt gatggaaatc ggttcttacc
    44341 gtggaatccg tcatcgccgt ggattgcctg ttcgtggaca aaacacgaaa aacaatgcac
    44401 gtactcgtaa aggcccagct cgcgctatcg ctggcaagaa aaaataattc ttaagtgaag
    44461 gaggttaaaa cttcatggca gcaaaaaaag tgaatcgtaa acgccgtgtg aagaagaata
    44521 tagaagcagg tattgcacat atccattcta cattcaataa cactatcatc atgatcactg
    44581 atactcacgg aaatgcatta gcgtggtcat cagctggttc attaggtttc aaaggaagca
    44641 aaaaatcaac tccttttgcc gctcaaatgg cagcagaaac tgctacaaaa gcagcaatgg
    44701 aacacggatt aaagactgtt gaagtaacag ttaaaggacc tggttctgga cgtgaagcag
    44761 caattcgttc attacaagct acaggtttag aagtgactgc aattcgtgac gtgactccag
    44821 ttcctcataa tggtgcccgc cctccaaaac gccgtcgtgt ttaatgagtg ccgctcattt
    44881 tgagttttat cagtaacgtc attgaacaag acacttttcg ttttgaaagg ggtaaagata
    44941 agaatgattg agttcgaaaa accaagaatc gcaaaaattg atgaagaaaa agattatggc
    45001 aagttcatcg ttgaacctct tgaaagaggg tatgggacta ctttagggaa ttccctacgt
    45061 cgtattttat tatcttcttt gccaggtgct gccatcacta atattcaaat cgatggtgta
    45121 ctgcatgaat tctctaccat caaaggtgtt agagaagacg tcactcaaat catcttgaac
    45181 attaaaggct tagcgctgaa aatgtatggc caagaagaaa aaacccttga aatcgatatt
    45241 accggacctg ctacagtaac tgctggcgat attatcgttg atagtgatgt agaaattctt
    45301 aacaaagata tgtacatctg tagtgtctct gaaggagcta cgttccatgc tcgcttaaca
    45361 gtgaaacctg gacgtggtta tgttcaagca gatgaaaata aaaaagaaga tatgccaatt
    45421 ggcgttcttc cagtcgattc aatctacaca cctgttcgtc gtgtgaacta tcaagttgag
    45481 aacacacgtg ttggacaccg tgaagatttt gataaattga cgatggagat ttggacagat
    45541 ggttcaattg aaccgttgga agcaatgagt ttgtctgcga aaatcatgac tgaacatttg
    45601 gatatttttg tgaacttaac tgatgaagca aaaaatgctg aaatcatggt cgaaaaagaa
    45661 gaaacacaaa aagaaaaaat gttggaaatg acgatcgaag agttagactt gtctgttcgc
    45721 tcttacaatt gtttgaaacg tgcaggaatc aatactgtac aagaacttac aaataaatct
    45781 gagcctgaaa tgatcaaagt ccgtaactta ggacgtaaat cattagaaga agttaaagca
    45841 aaattgcacg acttaggttt aggtttacgt aaagaagatt aaaacctttt acgaaggagg
    45901 gaaaccaacg tgagttatcg taaactagga cgcacatcta gccaacgtaa agcgatgttg
    45961 cgtgatttaa caactgattt attaatcaac gaacgtattg tgactactga agctcgtgcg
    46021 aaagaagttc gctcaactgc agaaaaaatg atcactttag gtaaacgcgg agatttgcat
    46081 gcacgtcgtc aagctgcggc tttcgtacgt aatgaagttg ccagcgtgcg tgaagaaaat
    46141 gaggacatcg tcattgaatc agctttacaa aaactgttca acgatattgc acctcgttac
    46201 gcagaacgtc aaggcggata cacacgcatt ttgaagacag aaccaagacg cggtgatggt
    46261 gcaccaatgg ttgtcttaga acttgtctaa aatcacacta ataacatcac tttatagatg
    46321 attcttttag agtgttatga tgttggaaga tatttttccg agtctagctc agcgctgctc
    46381 ctcaagcgaa tatcgcttgg ggagtaagca ctcatcataa agtgtttttt tataccttca
    46441 attacctgtc atgacagata tgtttgaagg cataaaaaaa cattttaagc gagaaataat
    46501 tgaaaatttt gtcttttttt gatagtgtta gtaggaactt taggatgaag aaggagtaat
    46561 catggagcca attattgaat tagaaaagat aaattataaa taccagccag atgatcttcg
    46621 ccccgcattg aaagatgtct cctttacaat tgataaaggt gagtggatcg ctattattgg
    46681 acacaatggt tcaggaaaat cgacacttgc caaaacgatc aatggattgc ttctgccaga
    46741 atcagggatc gtgaaagtgg gaaatcaaat attggatgaa gaaaatattt ggacgatccg
    46801 acagatggtt ggaatggttt ttcaaaatcc agacaatcag tttgttggtt cgacagtaga
    46861 agatgacgtt gcttttggtc ttgaaaatca agggattccc agagaagaaa tgctagtgcg
    46921 tgtgaaagat gcacttgaga aagttagaat ggctgagttt gcttcacgcg agcctgctcg
    46981 tttatcagga gggcaaaaac aacgtgttgc cattgccggc gtggttgcct tacgacctga
    47041 tatcattatt ttagatgaag caaccagtat gctagatcca gaaggtcgtg aagaagtgat
    47101 ctctacgatc aagaagatca aagaagaaag tcaattgacc gttatatcta tcactcatga
    47161 tattgatgaa gcagctaatg ccaatcggat actagtgatg agacaaggcg aacttgtccg
    47221 tgaaggtaca ccaaaagaaa ttttttctgc tggtcctgaa ctgatcgact taggtctaga
    47281 tctaccattt cctgaaaaac tgaagagcgc actgaaagaa cgtggggttg atgtgcccag
    47341 tgaatatatg acagaagaaa ggatggtgga ttggttatgg acatccgttt tgaacaagta
    47401 gacttcactt atcagccgaa tacaccattt gaacaaagag ccttatttga catcaatatg
    47461 acgatcaaag aaaacagtta tactgcatta gtagggcata ccggaagcgg gaaatcaacc
    47521 ttacttcagc atttgaatgc gcttgttaag ccaacaagcg gtacagtcca tattggagaa
    47581 cgagatattc agccggatac ggataataag aatttaaagc ccatccgaaa aaaagttggc
    47641 atcgtctttc agtttccaga agcacagcta ttcgaagaaa cggtagcaaa agacattgct
    47701 ttcggtccta aaaactttgg tgtcagcgaa gaagaagcac tagtcctagc aaaagaaaca
    47761 ttagaacaag ttgggctgga tgaaagctat ttggaacgtt cgccatttga actttcagga
    47821 gggcaaatgc gtagagtagc aatcgctggt gtgcttgcca tgaggccgga agtacttgta
    47881 ttggatgaac caacggcagg acttgatccc cagggtagaa aagaaatgat ggagatgttt
    47941 tggcgtcttc ataaggaaca gcagatcact attgtattag ttacgcattt aatggatgat
    48001 gtagccaatt ttgcagatta tgtctatgtg ttggaaaagg gacgaatcgt taatagcggg
    48061 gagccgcaag aggtctttca aaacattgaa tggctaaaag aaaaacaact aggcgtacct
    48121 actgccaccg agtttgcaga agaattaatg gctaaaggga tgaactttgc taccttgcct
    48181 ttgacagctg aagaattagc agacgctatc gtccattatg ctggaggaaa tgcccatgat
    48241 gaataaattg atatttggtc gttatatgcc tggagattcc ttgatccatc gattggatcc
    48301 ccgagctaaa ttattagcca gtttttattt tatcggaatc atttttttag caaataattg
    48361 ggaaacgtac cttttgttgg catttttcac attactttct gtcttcttgt caaaagtaga
    48421 tttgaaattt tttatccgag gcattcgccc attgatctgg ctaatcctct tcactgtagc
    48481 tttgcaggtc ttgtttacaa gtggcggaga aacttattgg agttggggtg ttttccatat
    48541 cactgaattt ggtgtgatga acggcctctt tattttctgt cgattcgtgt tgatcatttt
    48601 tatgtcgact ctactcacgc ttactacacc gcctttggaa ttatcggatg cgattgagta
    48661 cttgcttcgt ccattgaaag ccgtacggtt cccagtccac gaaatttcat tgatgctgtc
    48721 gattgctctt cgttttgtgc ctacattgat ggacgaaaca gaaaagatca tgaacgctca
    48781 gcgcgctcgc ggtgttgatt ttggtgaagg aaacctagtt cagaaaatga aagcagtcat
    48841 tcctttgctg attcctttat ttgtcagcag cttcaaccgt gcggaagatc ttgcgactgc
    48901 tatggaagca agaggctaca aaggtgggga aggaagaacg aaatatcgtg tattgcattg
    48961 gcataataga gacacgatgg ttatcattgc ttttgtatta ttaactgtgc tactgatctt
    49021 tttgagagga taaacgttca gtgggccgct atctattctt ttcttgctga tctgtttgca
    49081 agaaaggatg cgagcagtgt atgacaagaa atattagggt ctgtggcaga ctaaggtcac
    49141 aggcctcttt cttttatctg aaaagaaaga acgaaaaaat tttataaaaa aatcattatt
    49201 ccagataacc ttttaggaac aaaggagaga aaaacatggt acgttacaaa gcaatcattg
    49261 catacgacgg aacaaatttt aatggattcc aaaaacagcc aaatgggcgt actgttcaag
    49321 aagaagtaga aaaaacatta caaaaaatgg caaatggaaa agaaatcacg gtctttggtt
    49381 cgggaaggac agatgccgga gtacatgcga ttgggcaagt aatccatttt gattatccag
    49441 aggagcgtcc gttagaacga atgcgtttcg cgctagatac ccagtcacca gaggatattg
    49501 ctgtaagaca agtagaaatt gtttcagaag acttccacgc aagatatttg gtcaaagaaa
    49561 agacgtatca atttcgagtg gatataggga aaccacgcag tccttttcga cgccattatg
    49621 caagttattt tccttaccct cttgatttgg aaaaaattca gcgggcgctt cctgatttat
    49681 tagggactca cgatttcacc tctttttgtg catcaggaag ctcgatagag gataaagtac
    49741 gtacgatcta cgaggctaag atggaggtaa atgaaacaaa agacgaattg ttgtttacat
    49801 ttaggggaaa tggcttcttg tataagatga tacggatctt agtaggaacg cttttgaaaa
    49861 ttggcaatgg ccgattgcct gaagatagta tcccagatat tattgcgaaa aaagatcgta
    49921 atgcagcagg acctacagca catcctgaag gactttattt gtatgaagtg aaatatgaat
    49981 aagaggttgt gacagaagtg gtcagcttca agaaataaga aggaatttac gaaaattact
    50041 tctcaaaatt ttgcaaaatt tcggcttatt ttcgaaggag ctacttctgg aacaccgtga
    50101 atcagaggtt gtgaaaaagc tgccctgcat caagtaataa gaacaaccaa acaaaaatag
    50161 ctcgtcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    50221 ttaaggaaga ggttgtgaaa tcagcgtttt gacctgagta ttagagaaac aaacggaaaa
    50281 atagttcctc atattttgcc gtttgttgag ctaataccga aggtcagctg attgaacacc
    50341 gtttaagaaa gaggtcgtga gcctgtcatt taactctgag tcacaagtaa caatttcaaa
    50401 aaacagcttc tcatctttga tgaatatcgt gacttgtgga cgaggcgttg ataagtgaat
    50461 catctttttg ttacctattt tttctgtaac caaaaaacga tggaacgttg ttttgattgc
    50521 ccttaatgag gacagtcgga acaggtttgt catttttata tttaaatggc acaaattttt
    50581 ctaattattt gtcatttagc gctgaaaatt tttgctattt atctaaaaaa gtgataacta
    50641 cttaagatga agcagaatat ttacgccata cggcatacaa ccgcgaaaaa tataaaaaaa
    50701 agaaaacgat tgaacgcgtt tttgcagtcg caaaggaaaa gcatggaatg cgctacatca
    50761 agtatcgaga cttggaaaac aatcaggtgt atacgctgat tgtttttgct gcaatgaatc
    50821 tgaaaaagtt gtccacttgg cagttggaac atatgtcttc atatctttta ttatacaaaa
    50881 atagcaaaag caccagtcta cactcttagt aaagaggaaa ctgatccttt tgtctacatt
    50941 cttaaagtac ttaaactaag tactttattt tactctttag gattgataca gtagcatcta
    51001 tccctttatt aataatcttt tattttttta aataaagatg ttgtctccat cttcaggcac
    51061 taaaactttt tcggaaattc ctttttcttt attgaaagac tttaattctt ctcttgacag
    51121 tccccaatgg tttacagctt ccatatgaac ggcaataatt gtggaatctg gtattgcttt
    51181 atgcaattca tataaatcgt ctttccccat aataagagat tctccaacta aaaaatgatt
    51241 atctccagca tttgctacta tgatttctgg attatactga tcaatagttt gtttaacagc
    51301 ttcataccaa actgtatctc ctgtaaagta tagtgtcttc tcagtcgaat gtttgaaaac
    51361 aataccgcaa acattaccta cataattcaa gatttctcct ctgccatgtt tgccttttgt
    51421 tttaaccaat tgtatagatt caaaaactgt gtcttctcgt agtacctcca catttttaaa
    51481 accatatagt cgaatttcat tcgcatcatt ttcatcttgc acaaataatt ttatttcttt
    51541 aggtaggacc tctttcgcta tatcgtccca atgatctaga tgtaaatgtg ttacaataac
    51601 agcatcaata ccgttgataa tatcttcgac tggcattggc aaatcaacta gaggattcat
    51661 ttgatctttt cttggtgatg gaaaaggacc tttcgaaata aatggtggaa gtgttccttt
    51721 ttccgctaac attggatcaa ttaaaaattt tttacctcca tagtctaaga tagctgttgc
    51781 attacgaatg tgatgtatat tcataaacgt tgtctccttt ttgttgatat gaaatatttt
    51841 tagtataatt caattccata caataaataa accgaacaaa aaaagtcttt tactattttt
    51901 acttaattta tgaaaggttg tttaccatgt tagaccaaac agatataaat atcattgagg
    51961 aactatcaaa aaatagtcga atcacaatga aagaacttgg agaaaaagta catttgactg
    52021 gacccgctgt ctcggcgaga gtgacaaaac tagaggaaag tggagttatt gaaaattata
    52081 cagtaaaatt aaatatggaa aagctagggt tttcgattca cgctttttta attataatta
    52141 cgcaaaattt aaatcataaa ccctatttat catttattaa aaatcatgaa aaattcttga
    52201 ttagaaatta taagattagt ggagggggct gttatctttt ggaatgtaga tttacttcaa
    52261 aaaaat
//
LOCUS       DAMEEU010000010        50934 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.010, whole genome shotgun sequence.
ACCESSION   DAMEEU010000010 DAMEEU010000000
VERSION     DAMEEU010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 50934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.010"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(100..1251)
                     /locus_tag="PB779_000631"
     CDS             complement(100..1251)
                     /locus_tag="PB779_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HDE0738175.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(1405..1935)
                     /locus_tag="PB779_000632"
     CDS             complement(1405..1935)
                     /locus_tag="PB779_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDE0738176.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(2034..2384)
                     /locus_tag="PB779_000633"
     CDS             complement(2034..2384)
                     /locus_tag="PB779_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HDE0738177.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(2541..4070)
                     /gene="ahpF"
                     /locus_tag="PB779_000634"
     CDS             complement(2541..4070)
                     /gene="ahpF"
                     /locus_tag="PB779_000634"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HDE0738178.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(4080..4643)
                     /gene="ahpC"
                     /locus_tag="PB779_000635"
     CDS             complement(4080..4643)
                     /gene="ahpC"
                     /locus_tag="PB779_000635"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HDE0738179.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(4787..5449)
                     /locus_tag="PB779_000636"
     CDS             complement(4787..5449)
                     /locus_tag="PB779_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0738180.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            5633..7279
                     /locus_tag="PB779_000637"
     CDS             5633..7279
                     /locus_tag="PB779_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDE0738181.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAALLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPDMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDFQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            7270..8352
                     /gene="uxuA"
                     /locus_tag="PB779_000638"
     CDS             7270..8352
                     /gene="uxuA"
                     /locus_tag="PB779_000638"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDE0738182.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFELPGWEP
                     ERLAHIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLP
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNEYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(8460..10013)
                     /locus_tag="PB779_000639"
     CDS             complement(8460..10013)
                     /locus_tag="PB779_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDE0738183.1"
                     /translation="MQTQEAIKTFLLKKKSNTKLDIFLFLSEHRFFITTQYLADHFHM
                     SESNFLLYIKELEQDFERLNLTELHIDKQKPFLKLNFEGIDPAYCYYRLFGRYCNESV
                     SYQILTSLFSCQTNSIISLSQQTNYSASYLYTKMKKINAFLALYGLSISFSNNGRKSF
                     SGKEVQIQYAALDIYWNIFSSTATEFYDEDPQVVAFMMNTFFKKEVLDRLNSGMIDKL
                     YFLLKICKENFPATSVKDVQKEFTEYEYIDFFIDPSVDILRPNLPICREQRILVNILA
                     RLSITKIESEETSLEQYKLLKKANVPHVLYSREMVESFCTVFDLFIPEKEKILYSLAF
                     ARNKLYNGFLNFNQPNTPLPTFMLYQEHSVLKEVQTAIEQFYMDFREQNQHLLPVILE
                     KENVQWMVEDLVHLYDRYKKQPRIVIGVNYTRDFYISKDLIVKIEQIFSNESIKIQND
                     FMENCNIVISDCPLKQLPSHIKKIYILKGIITPEDWKKVIMRISEYIFELKEEALMDQ
                     SKKENQVTS"
     gene            10161..11449
                     /locus_tag="PB779_000640"
                     /pseudo
     CDS             10161..11449
                     /locus_tag="PB779_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(11575..12654)
                     /locus_tag="PB779_000641"
     CDS             complement(11575..12654)
                     /locus_tag="PB779_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDE0738184.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(12757..13197)
                     /locus_tag="PB779_000642"
     CDS             complement(12757..13197)
                     /locus_tag="PB779_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDE0738185.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(13254..13664)
                     /locus_tag="PB779_000643"
     CDS             complement(13254..13664)
                     /locus_tag="PB779_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HDE0738186.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAPGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(13844..14278)
                     /locus_tag="PB779_000644"
     CDS             complement(13844..14278)
                     /locus_tag="PB779_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDE0738187.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(14378..15226)
                     /locus_tag="PB779_000645"
     CDS             complement(14378..15226)
                     /locus_tag="PB779_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDE0738188.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            15615..17381
                     /locus_tag="PB779_000646"
     CDS             15615..17381
                     /locus_tag="PB779_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HDE0738189.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            17483..18742
                     /locus_tag="PB779_000647"
     CDS             17483..18742
                     /locus_tag="PB779_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDE0738190.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            18889..20190
                     /locus_tag="PB779_000648"
     CDS             18889..20190
                     /locus_tag="PB779_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738191.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSPQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            20193..21044
                     /locus_tag="PB779_000649"
     CDS             20193..21044
                     /locus_tag="PB779_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738192.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            21057..21872
                     /locus_tag="PB779_000650"
     CDS             21057..21872
                     /locus_tag="PB779_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HDE0738193.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            22023..23189
                     /locus_tag="PB779_000651"
     CDS             22023..23189
                     /locus_tag="PB779_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDE0738194.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
     gene            23419..24066
                     /locus_tag="PB779_000652"
     CDS             23419..24066
                     /locus_tag="PB779_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDE0738195.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            24150..25094
                     /locus_tag="PB779_000653"
     CDS             24150..25094
                     /locus_tag="PB779_000653"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HDE0738196.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            25229..26680
                     /locus_tag="PB779_000654"
     CDS             25229..26680
                     /locus_tag="PB779_000654"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HDE0738197.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            26701..27537
                     /locus_tag="PB779_000655"
     CDS             26701..27537
                     /locus_tag="PB779_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDE0738198.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            27537..28196
                     /locus_tag="PB779_000656"
     CDS             27537..28196
                     /locus_tag="PB779_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDE0738199.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            28322..29011
                     /locus_tag="PB779_000657"
     CDS             28322..29011
                     /locus_tag="PB779_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738200.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            29017..29973
                     /locus_tag="PB779_000658"
     CDS             29017..29973
                     /locus_tag="PB779_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HDE0738201.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHPIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            30017..30529
                     /locus_tag="PB779_000659"
     CDS             30017..30529
                     /locus_tag="PB779_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0738202.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(30785..31333)
                     /locus_tag="PB779_000660"
     CDS             complement(30785..31333)
                     /locus_tag="PB779_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0738203.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(31422..32603)
                     /locus_tag="PB779_000661"
     CDS             complement(31422..32603)
                     /locus_tag="PB779_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HDE0738204.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(32839..34347)
                     /locus_tag="PB779_000662"
     CDS             complement(32839..34347)
                     /locus_tag="PB779_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HDE0738205.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            34506..34697
                     /locus_tag="PB779_000663"
     CDS             34506..34697
                     /locus_tag="PB779_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738206.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            34900..35817
                     /locus_tag="PB779_000664"
     CDS             34900..35817
                     /locus_tag="PB779_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HDE0738207.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            35810..36883
                     /locus_tag="PB779_000665"
     CDS             35810..36883
                     /locus_tag="PB779_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738208.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            37031..37549
                     /locus_tag="PB779_000666"
     CDS             37031..37549
                     /locus_tag="PB779_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738209.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            37530..37922
                     /locus_tag="PB779_000667"
     CDS             37530..37922
                     /locus_tag="PB779_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HDE0738210.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            37998..38933
                     /locus_tag="PB779_000668"
     CDS             37998..38933
                     /locus_tag="PB779_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HDE0738211.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            39066..39845
                     /locus_tag="PB779_000669"
     CDS             39066..39845
                     /locus_tag="PB779_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDE0738212.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            39838..40155
                     /locus_tag="PB779_000670"
     CDS             39838..40155
                     /locus_tag="PB779_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDE0738213.1"
                     /translation="MTKLYLLLLVACLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            40399..42009
                     /locus_tag="PB779_000671"
     CDS             40399..42009
                     /locus_tag="PB779_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDE0738214.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            42166..43014
                     /locus_tag="PB779_000672"
     CDS             42166..43014
                     /locus_tag="PB779_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDE0738215.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            43245..43724
                     /locus_tag="PB779_000673"
     CDS             43245..43724
                     /locus_tag="PB779_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738216.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            43757..45985
                     /locus_tag="PB779_000674"
     CDS             43757..45985
                     /locus_tag="PB779_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0738217.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            46114..47757
                     /locus_tag="PB779_000675"
     CDS             46114..47757
                     /locus_tag="PB779_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HDE0738218.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKTNK"
     gene            complement(47830..48375)
                     /locus_tag="PB779_000676"
     CDS             complement(47830..48375)
                     /locus_tag="PB779_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HDE0738219.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(48398..48883)
                     /locus_tag="PB779_000677"
     CDS             complement(48398..48883)
                     /locus_tag="PB779_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDE0738220.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(48873..49685)
                     /locus_tag="PB779_000678"
     CDS             complement(48873..49685)
                     /locus_tag="PB779_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HDE0738221.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(49824..>50934)
                     /locus_tag="PB779_000679"
     CDS             complement(49824..>50934)
                     /locus_tag="PB779_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HDE0738222.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT        16889 a         9285 c         9770 g        14990 t
ORIGIN      
        1 ttttaagtac agtaaaagga ctgtggcgtt atcgtcacag tccttttttc aaataaacgg
       61 ttttcacgat gtctctttca caacttcttt ttgatttact cacacttcat aaactttttt
      121 tgtaaaatat ttgagaacaa gtggagaaat aagtgtactt aataaaatca cgataactaa
      181 aggtgaatag tactgtggtt cgatcaattg actttgctgt ccaatttgta aaatgatcaa
      241 agccatttct ccacgcgaaa tcataccagc accgaccatc aatgaactat gttgagaaaa
      301 accggcaatc tgagcaccaa aataacctcc aagcaatttg gtcaaaatcg ctacaagcgt
      361 caatatagaa ataaagagta gttgttcact aaagtcagaa aaatcaactt ctaatcctac
      421 actgacaaaa aatactggta taaatactgc atatcctaaa gcctctacat tgtggtatac
      481 ttcttcttta acctttgtct gactgacagc tatcccagca aaaaaagcac caatgacaga
      541 gctaagccca acaagatccg ctacgtaaga cattcctaaa caaataacta gcgatacgat
      601 gataatagaa gaatttgcgt acactttttc tgcaaatgaa agtaggaaag gcgcaatcca
      661 tttgactaat aagaaaataa aaacaaaata aattagctgt tcaatcaaaa caagcggtaa
      721 agaagcattg ctagaagctt cccccgttag aaaagatagg ctgaaactta gaactaaaac
      781 gactaaaatg tcatctacca cagaagcacc caaaattgtt gatccttctt ttgtattcac
      841 tacgtttagt tcttttaata cttctactga aatactgaca gaagttgccg caagaataat
      901 cccaaagaaa atcgcttcat ttcccgaaac ttggaatgct ttgcctgtca accagccaaa
      961 aacaaccggg aagatgatcc caagcaaagc aacgaacata ccaggtcgga aatatttttt
     1021 caaaagagat aaatcacttt ccagaccagc taaaaacatt aataagatca caccaatctc
     1081 cgaaaagtca tggactagaa tatcaggttt gacccaattc aatccagctt ggcctagcaa
     1141 aacaccaaca agtaattgtc caatcactgc tgggatacct aatctccgcg agatatgtga
     1201 gccaatcgtt gttgaaatca atatcaggca taaaatacca ataaattcca ttctcatcat
     1261 tcctttgtat aaaatatagc ccgaacttag cataacatac attattgaaa aaataggaaa
     1321 atatactcac aaaaaaacca acaatccaaa agattttttt ggattgttgg tttttatacg
     1381 gtctatttta ataactaaaa atgattaacg tatagtcatt tttcttattc tgatgaaatt
     1441 gataatctcc tggatgccca tgaaaatcaa aataaagccg aatatttgga atagaagcat
     1501 caaacttttg aatggattga acaataagac gaatccgcca atcaacaaca gaatactact
     1561 ataaacactc caacttttag cttttgtatt catgctgaag aacaactgga acaagctgtt
     1621 gatgataaca gctaatccaa gaagaatcgg caggatagaa acgattgcag gtgcaaaagc
     1681 atagacgatc agagctaaga tcaggaaaaa aagaccactg aacagaccga tactccaaga
     1741 acctgttttc cttttaaaac ggtaagcctc aaaaagattc aacaacccaa gcaaaacaag
     1801 ataggcggtg atcagataac cgataaaatg aaaaacagca gaagggttta gcacaatcgc
     1861 aatcccagaa ataatataaa cagcagctct taataaggcg tatttttgaa tattttgttt
     1921 aatcgtctca aacatataag aaaacctcct ttgacttatt ttaacgtgaa ctagtcattt
     1981 taccaaatta aatgttacaa aatgagcgaa ggagaagaat atctctggaa aaatcaactt
     2041 ctgaggatct tttccatttt tttgcctttt gctagctcat cgatcatttt atctaaataa
     2101 cgaatttctt tcatcaagtt atcctcgatg tcttctactc gtacaccaca aacaacacct
     2161 gtaatcaagg aacgtgaagg attggggaca ggggcttccg caaaaaattg ttcgaaagtc
     2221 acttgttttt gtagttgata ttctagttct gtttgggaat aacccgtcag ccaacaaatg
     2281 atttcatcta cttcctcttt tatacgatct tttctctccg cttttgctac atacatagga
     2341 taaacgcttg caaaacttgt cgtaaaaata cgattttgcg ccataatcag tcacctttct
     2401 ttttttcaaa ttatttacta cttatagtat ataagaaaaa gagaagaaaa agcgattatt
     2461 caaaaaaaca aaaaggattg tgacaaaatt cttgtcacca tccttttttc cgctctctga
     2521 ctttttacaa tcttcatagc tcaagtgcgc atcagataat cgaatgctcc taaagctgca
     2581 gtagctcctg aacccattga aacaatgatt tgtttgtatg gactatctgt acaatcacca
     2641 gctgcgaaaa cgccggggat attcgttgcg ccatttttct cggtcactat ttcatttctt
     2701 ggattcattt cgatcgttcc atctagccaa tccgtattag ggagtaagcc gactagaatg
     2761 aatactcctg aaacagctag tgtatgcatc tccatcgtac ggcgatcgat ataggagaga
     2821 gattctacct gattcgtacc gctgatttct ttcgtcgctg catgtttgat aacagtgaca
     2881 ttcgcaagag agactagttt atcctgtaag atttgatctg cttttaattc tggtaagaat
     2941 tctagaacat atacatgttt tgctaaccca gccaaatcga ttgctgcttc aacaccagaa
     3001 ttaccaccac cgataacagc aatctctttt cctttaaata aagggccgtc acagtgtggg
     3061 caataagcaa ttcctttatt tttaaactct ttttcgcctg gtacattgat agaacgccag
     3121 tgcgcacctg tcgcgatgat ggcggttttt gctttaagtg atataccgtt agctaagcca
     3181 atattaataa aatgttgctc tttatttaag gaaacggcct gttgattcat cataatgtcg
     3241 atagggtaac tacgcacatg actttctact tgctgcatca attttggacc ttctgtgtaa
     3301 gaggtaccaa tcatattttc aatccctagt gtttcaacga cttgtccgcc gaaagaatca
     3361 gcgacaagtc ctgtacggat tcctttacgt gctgcataga tagctgcact actagctgct
     3421 ggtccaccgc caattactaa tacatcataa ggttcttttt caaacaactc ttcttcaatc
     3481 aaagggccag tgattttttc aacaatttgt tcgatcgtca tgcgtccgct actaaattct
     3541 tctccattta aaaacacagt tggcactgcc atgatttttt tatcatcgat ttctttttgg
     3601 aacatcccac cttcaatcat cgtatgagta atatttggat ttaatacagc taatatattc
     3661 aatgcctgta caacgtcggg gcaattatga caagtcaagc taacataact gtcaaaatgc
     3721 aatgtttgtg ttattttttt gattttaaga ctcaaagatt cactgatttt cggtgcccgt
     3781 ccactaattt gtaacatagc cagtaaaaaa gaggaaaatt catgaccgag ggggatacca
     3841 gcaaaaacga ttccactttc tttgccaact ggattgatag aaaaactagg tgtgcgcatc
     3901 gaatctcttt tttcccaaga gattttagga gacatttctg ctatttcctt cgtaaattca
     3961 gctagttttt gactattttc actattatcc aaactaacag aaaaaacaat aggagattca
     4021 atcagtgcta aatattgttc gagattttgt ttagtttctt tgtctaacat atccaccacc
     4081 taaatctttc caacaagatc aaaacttggt ttcaatgttt cgccactttc tttccatttt
     4141 gccggacaaa cttcacctgg gtgggtacgt acatattgag cagcgcgaat cttatcaatc
     4201 agtgcactag cgtcacgacc gattccatct gcattgattt ccatagcttg aacgattccg
     4261 tctggatcaa taataaatgt tcctcgctga gctaatcctt gctcttcatc caaaacatca
     4321 aaaatacgag aaatctgatg agacggatca ccgatcatca cgtattcgat tttaccgata
     4381 gcatctgatg tatcatgcca tgctttgtga gtaaagtggg tatcggtaga gcaagaaaag
     4441 acttcaacac ctaaagattt caatgtactg tattgttctt gtaagtcttc taattcagta
     4501 ggacaaacaa aagtaaaatc agctggatag aagcaaagaa tactccagtt ccccataaga
     4561 tctttttcac tgacttctaa aaattctcct tgatgataag catgtgcatt aaattcttcg
     4621 atttttttcc caatcaatga catagtaaaa cctccaataa taattattta tttataatta
     4681 ttgtaattta gttggagttg caaagtcaat ggatattttg ttatttaata aagattactc
     4741 aaaaacgaag gttaattata aaaatagaag aggtcgcaag aaaatgctac tgctggaaat
     4801 actcgggata acgttgagta acagtttcct gttctttcag catcatgtgt aagtgcaatc
     4861 ccgtttgaaa tcgagcttct tctggttttt tatcaactaa agccttgagt aaatcataat
     4921 gttgttccat gatcgtttcc catggaagcc cctgaatggt cactcgtaac cagcggaaac
     4981 gttctaaatg ggtattatgg tcatctaacc agttccaaac ttcttttctt cctgcaattt
     5041 cgaaacaagc ttcatgaaat aaattatctg cacggaaaaa agcgcgttcg tcatttattt
     5101 tgactgcttt ttcttgttct tctaaaatcg tttctagcac tattcgtgtt tgtgtgtcca
     5161 atttggaaca acattcaatc atgatttgct cttccaactg ttctcggaca aagcgagcat
     5221 tttctgcaga aacaagatta attttggaaa catacgtacc actttgaggt atcgtataca
     5281 cgagttcttg ctgacgtagt tgaatcaatg cttcgcgaat gggagtccgg ccgatagcaa
     5341 gatgttcctc cagtgccttt tcagatattt tccttccagg ttctaagtca gcatagataa
     5401 tttgtttacg aatcgcttga taagcttgtg attgcaagct gcttttcatc tttattcctc
     5461 caaaatcatt tctatgaacg tagtataaca gaagaggtct gaaaaacaat ctggtatgtc
     5521 acattaacta gtaaatttgt ataaatagta aaattttggt tgacatagcg atttttattg
     5581 tataaaattc acttgaatac aaaaactaat atgttagttt aggaggggaa aaatgattga
     5641 tttaaacaac tggaggaact ttatccctga attatctcaa aaagaagtag aaatacctca
     5701 ttttgaccgt gcatcattaa gagaaaatgg acaaaaaaat cctgtctgga tccatttcgg
     5761 tggcggaaat ctttatcgag gatttcatgc agaaatcgct caacgtttag cggatctagg
     5821 cgaattgtcc actggtgtca ttgtttgtga aacattcgat gaagaaataa ttgaaagggc
     5881 ttaccaagat tttgatgatt tgattcttga agtggtcatg ccaagcagtg gagagttcgt
     5941 caaacgtata ttagctgcga cagctgacag tctgtattgt catccagatt gttctgaaca
     6001 ctttgataag atgattcgac actttgaaaa tcctagttta caattagtta cttttgctat
     6061 tactgaaaaa ggttatcgat tgaaagatac aaataataaa tatataggac cgattgcagt
     6121 cgatataaaa aatggtccaa agaagccatc acatacaatg agtattcttg ctgcgctact
     6181 ttataaacgt tttttatctg gagcttggcc gattgcactt gtctctacag ataatttttc
     6241 acaaaacggt agtcaattac gtacttcttt gctaacgatc gcaaaagaat ggcaaaagga
     6301 aggttatgta caaaatacat ttatccaata cttatcgaat gaagaaattg ttgcgtttcc
     6361 atggacgatg attgatcgta tcaccccgaa tccttccttg tcagttagca aaatgttggc
     6421 aaaagagggc ttttcaaata tgtcgatttt ccaaaccgca aaaggaaata atattgctcc
     6481 atttgtcaat acagaggaca tccattattt aatcatggaa gatcattttc ccaatggacg
     6541 tccgaaattc gaaaaagctg gggtattctt gactgatcgt gcaacggtag ataaagcaga
     6601 tacgatgaag gtgacgactt gccttaatcc tttgcatacg tctttagcta ttatgggttg
     6661 tttactgggg tataggagca tagctgagga gatgaaagat ccagatttat cgctgctagt
     6721 ttctgaaatc gggtacaatg aaggcctccc agttgtggag tctccaggta tcattgatcc
     6781 aaagatcttt ctggaagaag taattactgt gcgcttttct aatccaaata ttcctgatat
     6841 gcctcagcga atcgccacgg atacctctca aaaggtggcg attcgttatg gtgagacgat
     6901 taaaaaatat atggaaatag aagttaaaga cccgcagaca cttgtattca taccattgac
     6961 tctcgctgct tggcttcgat accttattgg cattgatgat caaggaaaac cattcatccc
     7021 gagtccagac ccactattga cagactttca gcataagctt tccgatattc aactgggtac
     7081 gcaagataca tcacatattc atgagaaaat ggctcctatt ttgtcaaata aagaaatttt
     7141 tggtgtagat ctttaccaag cagagcttgg cagaaaaata gaagaaatgt tcatcaagat
     7201 ggtagcagga ccgaatgccg tacgaaaaac attacaggat tacttacaag aacatggagg
     7261 aaatttatca tggaaatgac ttttagatgg tacggatcac aggaagaaaa gattacctta
     7321 gatgaaatca gacagattcc tgcggtcaaa gggattgtag gcacattgat ggatatacca
     7381 gtaggagagg tatggcccag ggagaggatc aaagaactaa aagaagaaat tgagtctcgt
     7441 gggttaacac taaaagtaat tgaaagcgtc aatgtgcatg atgccattaa aattggatta
     7501 ccttcccgtg agcagtatat cgaaaactat aagcagacaa tccgaaactt ggcagaatat
     7561 ggaatagaag tcatctgcta taattttatg cctgtatttg actgggtgaa atctgacctt
     7621 gactaccgct tagaagacgg ctcatccacg ttagctttta tatctgatga tattccagat
     7681 gatccaagag aaatcgtcgc gcgcatcgaa cattccagca atgaatttga attgccggga
     7741 tgggaacctg agcgcttagc tcatatcaaa tccttgcttg aagcctatgc atcagtagac
     7801 gaagaaaaac ttcgagaaaa ttttgcctat tttctccaat caatcatccc aacatgtgaa
     7861 gaggtagggg tcaaaatggc tgtacatcca gatgatccgc catactcgat ttttggatta
     7921 cctcgaatcg taaagaatcg agaagattta gattggttgt gccgcatagt agacagccct
     7981 tataacggaa tcactctttg tacagggagt attgcagaag atccagaaaa tgatgtatat
     8041 gggattttag cagaattttg tcaaagagat cgaatcccat ttgcacatgt tcgaaatatt
     8101 aaatttttag ctaatcgaga tttctatgag gcaccgcata aatccgaata cggttcatta
     8161 gacatgtacc gcatactaaa aacaatgtat gacaacggat ttaacgaata catccgtcct
     8221 gatcatggaa gaatgatctg gaatgagaca ggaagaccag gatacggctt atatgatcga
     8281 gcattaggtg ctgtttatct aaatggatta tgggaagcaa tcgaaaaagg aaacaaaagt
     8341 aaagataatt agtgaaaaaa actgtaattt tattatgtaa ataagaagga tgttcaaatt
     8401 cttgatacat aaatccggag gttgttaata agcattcgga tttatgtatc ttatttggtc
     8461 taggaagtaa cttgattttc ttttttcgat tgatccatga gtgcttcttc ttttaattca
     8521 aagatatatt ctgagatcct cataatcact tttttccagt cttctggtgt gatgattcct
     8581 tttaaaatat agattttttt gatatgagaa ggcaattgtt tcaaagggca gtcgctgata
     8641 acgatgttgc agttctccat aaaatcattt tgtattttga tcgattcatt tgaaaaaatt
     8701 tgttctatct taacgatcag atctttactg atataaaaat cacgcgtata gttcacacca
     8761 atcacaattc gcggctgttt tttgtagcga tcatacaaat gtactaggtc ttcaaccatc
     8821 cattgcacat tttccttttc taaaataact ggtaacaagt gttgattttg ttctctgaaa
     8881 tccatataaa attgttcaat ggcggtttgg acttctttca acacgctatg ttcttgataa
     8941 agcatgaaag taggaagggg cgtatttggt tgattgaagt taagaaatcc attataaagt
     9001 ttatttcgtg cgaatgccaa tgagtaaaga atcttttctt tttcaggtat aaacaaatca
     9061 aatacagtac aaaaggactc caccatttct cttgaataaa gaacatgagg aacgtttgct
     9121 ttttttaaaa gtttgtattg ctccaagctt gtttcttccg attcgatttt cgtgatagaa
     9181 agtcgagcta aaatattcac taagatgcgt tgttcgcgac aaattggcag attaggtcgc
     9241 aaaatatcta cagagggatc aataaaaaag tcaatatatt catactctgt gaattctttt
     9301 tgtacgtctt tcacagaagt tgcaggaaaa ttctctttac atatttttaa tagaaaatat
     9361 aatttatcta tcataccgct atttagtcgg tcaagtactt cttttttaaa aaaagtattc
     9421 atcataaaag ccactacttg cggatcttca tcataaaatt ctgtagcagt acttgaaaag
     9481 atgttccaat aaatatctaa tgctgcatat tgaatttgta cctcttttcc agaaaaagac
     9541 tttctgccat tattagaaaa ggagatagac aaaccgtaca atgctaaaaa tgcattaatc
     9601 tttttcattt tcgtatacaa ataagaggca ctatagtttg tttgctgact taaactgata
     9661 atcgaatttg tctgacagct gaacaaagaa gtcaagatct gataactgac tgattcgttg
     9721 cagtatcttc caaatagacg ataatagcag taagccggat caattccttc aaaattcaac
     9781 tttaaaaaag gtttttgctt atcaatatgc agttctgtta gattgagacg ctcaaagtct
     9841 tgttctaatt ctttgatgta tagtaaaaaa tttgattcag acatatggaa atgatctgct
     9901 aaatattgtg tagtaataaa gaaacgatgt tcagatagga aaagaaaaat atctaatttt
     9961 gtattgcttt ttttcttcaa gagaaacgtt ttaatcgctt cttgagtttg catgaaagag
    10021 gctccttttt acttaaattg ttaaaacttg aaaatattac tgtttttttc ataaatttag
    10081 acaaaaaaac agtaaacata taggtagaat ctctactatc ttatttcttg catacaaaaa
    10141 aatcaaggag tgagagagtt atgagatatt caaccatctt aatatcaaca tttgcagcct
    10201 taagcttatc gcttactata aatcagacag tccacacaga ggagatagaa acagccaaat
    10261 ggacagaaac caagtgggcc aacgtcaatc gaattacctt tcaggatgaa ttttcatcct
    10321 tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg
    10381 actattcagg agacttagca cctatactac aatcagctgt tacatttgag aatgttgatc
    10441 ccgctttgtc gattggctat gacgagaaca ctttgactat ccaacacaag caagcgatat
    10501 ttaccttcac cgttacatta aatcaggact tgttaaaacc agcgcttttt actgtcaagg
    10561 tatcagatgg actaccgaac gatcatcatc atttaacgcc gtatagtcag cggcagacaa
    10621 ttgagcaaga ttcagctatc gactcaggag gagatcttgt tgaagaacca acagataaac
    10681 cagaaaatga aaataagcca gaagtaccgc ctacagaaaa tccagacgga gaacagaaac
    10741 cggaaataga acctggagaa gaacccgata cagaaactca accagagcca gacaatgaat
    10801 caaaacctga aataacccct ggagaaaaac cagatgtaga cccagaagaa aaaccagatg
    10861 tgactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
    10921 cagataatga aactgaaaat ccagaaaaac cagaggtagc cccagaagaa aaaccagatg
    10981 taactccaga accagatacg gattctggaa accaaacagt accggaaaca aatccagaca
    11041 cagataatga aactgaaaat ccagaaaaac cagaggtaga tccagaagaa aaaccagatg
    11101 tgactccaga accagatacg gacgcaagag accaaggaat accagaaaaa ataaacaaaa
    11161 aaacaattca agaggatgga aaaaaagaga gtaaaaaatc aaatctagca attctaaaaa
    11221 taaatgaaga gcagctgaat aaaaaatcac gaatatttga tagcgcccaa tcagctgaaa
    11281 ccttaaaaag tagcaaggat acaacctttg ctgtcctgaa acgaaaaata aacagctacc
    11341 aaaatccgga gagtcacaaa acaaagttat actgtggagc ggaatcattc tattaagtat
    11401 agcaacaatg ctttctgcaa aaagatttaa acaaaacaga tctctctaac atttgaataa
    11461 tgtctgtgaa cgcatttttc aaataaaaag aaatatccag aaaatgaccc caaaatacca
    11521 gattgaaatc tgatatttgg ggtcgttcat actttatctt tcttcatatt tattttaagg
    11581 gatatctgtt tcttttggaa gatggttcgg gatctttttc actttcaata catctaaaaa
    11641 gaaggtaaag atcggaatgc cgacaatcaa gccccaaacg ccaaagaacc gttcgctaac
    11701 aagtaagacc acaaatgtat aaaaaatcgg cagttctgtt ttgctggaca tcaacttcgg
    11761 attcagcaca taagactcaa ttagatggac aatcaaaatc gtaatcagga tataaacaac
    11821 atctcggatg cctccttggg aataagctat gaaagataga ggaatacaag aaatgataac
    11881 acctgctact gggatcagac ttaaaatgaa aatcatgatc gctaaactca gcagctgatg
    11941 aaagccaaat acagccaagg cgattgtagt gagcaacgta tttaaaagag cgacaacaaa
    12001 ttgagcttct aataccaaac caaatgtatt gacaaactta tcggcaaaat agtaaatatc
    12061 ttgaaagaac caagaaaatt cactttttaa aaacaatctt gagaatacaa ttgttttttt
    12121 cttttcaatc ataaaaaaga aacttaagat gaatgacata gcaaacgcca ctgccatttt
    12181 tcctatatcc tgtaaatagc caagcgcaat cgaagcgcca ttttgaagct gttcaaaaaa
    12241 atcgtttcgc tcaatataag tatggatata ttgtaaaaca ggatctgcat cttttggctg
    12301 atgctcgtaa aaattaataa cggactggat catgtcaaat gtttgatgaa taagcatcgg
    12361 gatatacttt gtgaatgcca gatagataag gtaaacgatc agtgtataaa tcatgatagc
    12421 taaaacacct gtagggattc ggacaaatcg ctgaatgatt tgaacaagat gaatcatcaa
    12481 ataagtaaag ataaatgtga gcaaaatggt tgtaatcata cttctaacta agaaaagaac
    12541 aaaaacgaca aataataaaa cagtgagacg gcgtattttt tcattcgcca aaaaacgctg
    12601 ataaacggtc aaatcgacaa cctccaaata acaaaaaata aacacgttat tcattatatg
    12661 atggaatatg aaaataagaa agagcaaaaa gaaaaaccgc taaatgacgt tatcttatga
    12721 gttggttttc ctcataaaat cgttcatcta gcagtttcag ccctttttct ggtcttgatg
    12781 aaaattatct agcatttttc gggtcagatg ttgcagtgta tccaattctt cctgttcaag
    12841 tggaagataa gacttgatct tttgtggaat accttctgct tgtttttgca acgcagcacc
    12901 ttgagcagtc agcgtaacat ttacgattct ttcatcaccc gtttcacgct gacgattaat
    12961 ataatttttt tctgctaact tttttagtaa gggagtcagc gtaccagaat ccagacacaa
    13021 atcatttcct agctctttca ctgaagtctt tttcttttcc cataaaacta acatcacaag
    13081 atactgggta taggtaagat tcagcggctt gaggagggga gtgtagtgtc taatgatttc
    13141 tttagaggcg gcatataaag gaaaacatac ttgattaact aaatatagat cttccatttt
    13201 tccacctccg ctgttttact atagtgtatc atagcggatt tacacaaaaa agtctattca
    13261 ctaactgctt tcagagtaac ttctatattt ccagctgtag cttttgaata cggacacact
    13321 ttatgcgctg cctctaataa ttcttgcgtt tcttccagag aaagaccttc gatagatcct
    13381 tcaatctcta cacctaagac aaagctcgtt tcactttctg aataaaggga aacttgtgca
    13441 ctgacagtag aagccccaga gatatttttt tgctgtttga tcaattctaa tgcactgtta
    13501 aaacatgcac tgaaaccagc tgcaaacaat tgttcagggt tggttgcatt ttcgacgcgt
    13561 ttaccaggag ctgcaatatt caattcgaat gtacgatcgg gattatgcac ttctccagag
    13621 cgtccgcctg tgttgatcat tttcgtagaa tacatttttt tcataaaatt accaccttta
    13681 attatatttt atacaattga attttacaca atataattgt ggaaagcaaa gaaatggatt
    13741 ggcataagat aaataagaga aagcacatga aacagacgcg ctttctcgaa tagcaaacat
    13801 atacaaaaaa tatcagagac aaaaaataat ctcatcataa acattacata tatttctcaa
    13861 aaagttgttt tctttcttca aaaattactt cacgatggac ctgatgaagc atccataaat
    13921 aaccaaaagg atctctgaac attgagttag tcacaccaaa gtccatcatt tctgtcattt
    13981 cttgaatctc tacacagcca tttcgtaatg ctttattatg tgtgtcctcg atatcagaga
    14041 cgatgatatt gaaccagatc gtatttggat gttcagcagt aggagcagtc aaaccaagag
    14101 acgtgttttc atccagcata tggaatctcg taccatacaa ggtaaaaatg acttcattat
    14161 tgcctctagg gtaatctgtt gcctcaatca gttgtatttc atcaaagatt gtttgataca
    14221 gttctagtgc tttcaaacta tcatttaata caaaatcgat ttccgttcct ttatgcataa
    14281 agatctcctc tccttttcag tcgaacagtt actagattct tttattatac cagctaaaga
    14341 aaacgcattc aaaaaaatag cggatttact taccaactca ttcgattgga tgataagtaa
    14401 atccgcgtcc cattacttct gctacgctgc tgacaatgac aaaggcactt ggatcgattt
    14461 cttctatcaa tggtttcatt cgggaaaatt catgatcagt cacaacgatc aataaaacct
    14521 cttttgactt tcgattatac ccgccttttg cctctagcag ggtaaggcca cgtccaatct
    14581 cagcacttaa gcgaaggcgg atgtcttcca aataatgttc actcatgacc ataacagatt
    14641 tctttcgatt gatacctgtt tcgatataag tcatgacaat tgaagtgatt gcaatagata
    14701 aaatagcata aagaaactct tctattccaa aaataaacag attaagagaa acaacgaatg
    14761 cgtctgtaaa aaataagcca atcgaagtat tcaagtggaa atatttttta aaaatgaggg
    14821 gagggatcgt cgtaccgccg ctagaagagt tgtttttata taaaatcgca actcctaaag
    14881 caaaaatcgc acttccaaaa atgacagaca acaaccgatc tgaagtaatc attgtttctg
    14941 gaactattgc aatgattaaa ggaaaaacca agcttccgaa aagtacttta aaaaagggtt
    15001 ttttacctaa aaatagaaga gctagtacca acataacgat attcaacact aaaataacta
    15061 tagctcggtc aaagcctaaa gcagcttcca gtaatattcc tagaccgctg acacctccag
    15121 cagcaatatg atgaggccct aaaaacatat tgatagcgac tcctaatatg aagagggcaa
    15181 aaataatctt aatgtatgtc catataaatt gtctcgtttc tttcatttat tcacttcctt
    15241 aattcattaa taatactctt atcttattat aacttacttt tcaccttaag ttaactttaa
    15301 ttaataaaaa aattaggcta gtctaaatta ttatgtttca ttcttctaga atatacttct
    15361 acgccaaaaa ctgttaaaaa acttttactt tagaaaattg gagaaattga tcgcttaaga
    15421 taaattcagg acactaaata gtacaggaag tagactaaaa cttttaaaag ttttaagtct
    15481 atctatttgg caagtttaaa aaataaaaat tcggtatcaa aaaactgtta ccgataacat
    15541 ttttgaaagc gttgtctttt gcttctctat cacttatagt gatgacgtca tattaaaaca
    15601 caaggaggaa atcaatggat acagctgcaa tttatcatcg accggaaagt gaatatgcat
    15661 ttctatatac gaatacaaga tttcgtattc ggcttcgtac taggaaaaat gatatcaaaa
    15721 aagtatatgt gctatgtgga gatccatata ccataacaac tgaaaaatgg tatcaaaaac
    15781 aacgaccaat gaaaaaatgt ctaagtacca atgttcatga ttattgggaa attgaagtga
    15841 cgagcgaaac aagtcgctta cagtatgcgt tccatgttgt tggggaagat aacacggact
    15901 gtttttacgg tgatcaagga atttttcctt atcgagaaaa tgtgattact gaaccaaatt
    15961 tttattttcg aataccttat tttcatcaaa tcgatcgatt cactattcca gaatgggtaa
    16021 aagaaacagt atggtatcaa atttttcccg aaagatttgc aaacggggac aaagcaaatg
    16081 accccgaaca cactttacct tggggaagta aagatccaga ccgagaagac tttttcgggg
    16141 gagatttgca aggtgtgatg gatcatttgg attacttgac ggaccttggc atcaatggca
    16201 tctatttttg tcccatattt aaagccacat ccaatcataa atacgatacg attgattatt
    16261 atgaggtgga tcccgctttt ggcgataaaa aacttttaaa aaacttgatt gatgaagcac
    16321 ataaaagagg gatacgtatc atgttcgatg ctgtattcaa tcatatgggt gtccattcac
    16381 cacagtggca agacgttctc aaaaacggag aaaaatcgat ctataaagac tggttccaca
    16441 tccgtttttt cccagtagat tcttatcaga tgactgactt accagaaact gctgaaaata
    16501 tcccatatga tacttttgct tttactccat tcatgccgaa actaaataca gcaaatccag
    16561 aagtgcaaaa atatttgctg gatatcgcaa cttattggat aaaagaattc gatattgatg
    16621 gatggcgtct tgatgttgct aatgaagtcg atcatcattt ttggaaaaaa ttcagagaag
    16681 cagttacaga aatcaaacca gacatctata tccttggaga gatttggcat tcctctcaag
    16741 cttggctgca aggggatgaa ttccatgcag tgatgaatta tgcatttaca gattcgatta
    16801 aagattattt tgcaaaaaag aaaatcacag cttcacaaat ggtcagtgga atgaatcatc
    16861 agcaaatgct ttacagagat caggtgaacg aaggaacatt caacttatta gattctcatg
    16921 atactgccag gatcttgacc ctttgccaag gtaacaaaga attgatgaag tctgtgatgg
    16981 cctttatgtt tcttcaaaaa gggtctcctt gtatctatta cgggacagaa atagggatga
    17041 ctggtgaaga tgacccggat tgccgcaaat gtatgatatg ggagaaggag gaacaagatc
    17101 tagagctatt cggttttata aaagaacttg tttctctaag gaaacagttg tctaagatta
    17161 tttctgaagg ttctactcag tggctaatag taaatgatcg tgaagataag ctctatttca
    17221 cacggaaact agagggacag atcatctatg tttactttaa tcagtcaaaa gaaccttggg
    17281 tagtagaaca ggaaaatgag gtgattctta gtcaaaattg tcagttgtta gaagacggga
    17341 aagcagagat acgacaatac ggatttttga tcatgtgttg aaaactgtta ccggtaacaa
    17401 caagaaagcg tttgcaaatg aagatttgtg cccattataa taagggtgta acagcacgtt
    17461 gaatacaaag gaggaaatga agatgaaaaa aagaagtgtg aaacagttgg gtttagggtt
    17521 aatctcttta ggaatcttag gcggattagc ggcttgtggc aatggtaact cttcagcaga
    17581 aggggaagcc gatgaaggaa aaacgttaac agtttccgtt gattctggat ataaagatta
    17641 tataaacgaa ataaaaaaca ctttcgaaaa agaaaacgat gtgaaaatca agctagtaga
    17701 aaaggacatg ttcgatcagt tggaatcatt agcgttagat gggcctgctg gaaagggacc
    17761 tgacgttatg atggcagcat atgaccggat cggtgcgtta ggacagcaag gacatctggc
    17821 ggaagtaaaa ctgggaaatg aagcagctta cgatgaaaca gacaaagccc aagtgactta
    17881 tgatggaaaa atctacggag aacctgcagt aatcgagacc cttgttttgt actataacaa
    17941 agatttagtc gatacagcac catcaacgtt taaagatttg gagaatctat ccaaagacag
    18001 tcgttttgct tttgagtcag aagcaggaaa aaatacagga tttttagcta aatggactga
    18061 cttttattat tcctatggtt taattgcagg ttacggtggc tatgtatttg gtgatgatgg
    18121 cacaaatcct tcagatatcg gtttgaataa tgcaggtgct gtagaaggaa tctcttatgc
    18181 aacagattgg ttcaaaaatg tttggccaaa gggaatgcaa gacataaaaa gtgcaggaga
    18241 cttcgccagc cagcaattca tgtccaataa aactgcagca atcattgacg gtccatggca
    18301 agcgcaaaca tacaaagaaa acaatatcaa ttatggtgta gccaaaattc ctactctaaa
    18361 taatggacag ccttatcaac cgtttggcgg aggaaaagga tgggtagtca gcaattatgc
    18421 taaaaacaaa gacctctctc aaaaatggct tgattatgta acgaatcagg aaaatcaaga
    18481 aaaattcttt gaaatggtaa atgaaatccc tgcaaaccaa caagctaggg aaacagcaaa
    18541 ggctaaaaac gatgaattaa caacagctgt gattgaacaa tatgaaacag ctcaagcgat
    18601 gccaaacatc ccagaaatgg gcgaagtttg gacaggtgca gaaaacttga tgttcgatgc
    18661 agcatcaggt tcaaaaacac caaaagaatc cgcagatgaa gcagtaaaaa caatcagtga
    18721 agccatagaa caaaaatact gattaaaatg ataaccgtcc atttttataa aaaatggaac
    18781 aggtgcttca gataaaagtg gcaagagcga gatggaaaat tatcttgctc ttgttgccat
    18841 tatcttaaaa gcagtttgcg gtttagcaag tttagagggg gcattcagat gcagcaagat
    18901 aaaacaagca atatcaacga aaaaaaaatc acgctttgtt cacttattcc agggatgggg
    18961 cagtttgtaa atggccaagc ttttaaaggt atcgtttttt tcgccatatt cgtcctattc
    19021 attggtcaga tgcttctggg cggatttcat gcattggtag gattggttac tttgggaagt
    19081 ataccaatgg aagatcattc attatttatt ttgattgaag gcactttgca attcatcatt
    19141 acaatcattt tcttgatttt ttacggtttg aatcttttag acgcttatcg agtagcgaag
    19201 atgcgtcaag agggcaaaaa aatcaatcgg acgatgaagg aagtcataca taatataggt
    19261 gatgaaggtt ttccttatct attgacactt cccgcttatc ttctcatgat ttttacgatc
    19321 attttcccag tcctagttac attgttcact gcatttacta attatgactt caatcatatt
    19381 ccaccagcca gtttaattga ttgggtaggg gctaaaaact tttttagtat cttcttttta
    19441 agctcatatc gtaatacttt ttttgcagtc ttttcgtgga ccgtgatttg gactttatgt
    19501 gcaacaactt tgcaaatcac ccttggtatt ctcacagcgg ttgttgctca ccagaaattt
    19561 attaaattca aacgtatttt cggtatcatt ttcttattac catgggcggt cccagctttt
    19621 attactatca tgagtttttc gaatatattc aacgatagcg taggtgccat caatactcaa
    19681 gtgattcctt tcataaacca gcttcctttt gtagatatca gtgcaatctc ttggaaaacg
    19741 gacccgaact ggacgaaagt agcaattatc ttagtgcagg gctggttagg atttccctat
    19801 atctatgtga tggttacagg aatcttacaa tcgatttcag aagacttata tgaagcagca
    19861 aaaatcgacg gagcaaatgc atggcagcgc ttttcaaaca tcacgcttcc tgctgtcttc
    19921 ctagtggcag cgccaacatt tattacacag tatacgggga atttcaataa tttctccatg
    19981 atctatctgt ttaacaatgg cggtcccgga agcgtaggcg gaggagctgg ttctactgat
    20041 attcttattt cctggatcta taaacttacg actggaactt ctccgcagta ttctatggct
    20101 tcagcaatca cgttgattat ctccgtcatc gttatctgtg tgtcattgct ggtatttaaa
    20161 aagacaaatg cgttcaatat gggggattaa caatgaaaaa atttcattcg agtgctcgat
    20221 tccaaaaacg actttctcac ttttttactt acttttttct tttaatactg tcagtcatta
    20281 tcatctatcc gcttttgatc acagcaagta ctgccttcaa gtcaggaaat attgcagctt
    20341 ttagtttaga tctttcaagt gactggactt taggaaactt tactcggcta ttcagtgaaa
    20401 cactttacgg gacttggtat aaaaatacat tgatcatttc tgtcctaaca atgatcgtac
    20461 aagtgactgt agtaactttg gcgggctata cttatagtcg ctatcgtttt atcggccgca
    20521 aatcaagttt gatgttcttt ttagtgattc agatggtacc gactatggca gcattgactg
    20581 ccttttatgt catggctttc ttattagaag cgctcgataa gtactggttc ttgacaatga
    20641 tctatatagg cggtggaatt ccaatgaata cttggctgat gaaaggatac tttgacactg
    20701 taccaataga tttagatgaa tctgctaaac ttgatggggc agggcatttc aggatttttt
    20761 tccagattgt attaccgctt gtcaaaccga tgctcgccgt tcaagcatta tgggctttta
    20821 tgggaccttt tggggatttc atgttagcta agttcctgct tcgaacacct gaaaatcaga
    20881 ctgttgctgt cggcttacaa acatttattt ctgatgtgac aaaccaaaga gtctctcttt
    20941 ttgctgctgg ggcaattttg attgcactac cgatttgtct attattcttc tttttacaaa
    21001 agaactttgt taccggcctg acatctggcg gaacaaaagg ataggagcag agtatcatgc
    21061 aaacatttcc gttaaactat ttttccgcat tacgtacgcc aactcaagtg tttgcgggac
    21121 gcaaactatt atcatggcct aaatttttct tgatatttgt atttttagtt tccttgatgg
    21181 tcatgcctgt gactcttttt tatgccaatc agatccaagc gattccatta gaacaatttc
    21241 tatccgttca ttcgctgatc gatgaacaag gaacccaaaa attttctgaa cttgaattat
    21301 ctgaaactgg gttacaagca tcgcaacaaa cgatagctgt gacccctgaa attttggtag
    21361 gtgtgtcttt atctgagaaa caacaatccg atcatggaac ttttattgat tttgagaagg
    21421 aacaatgggt gatccaacaa aaggataaat ctggtatacg ccgctatacg atgaattata
    21481 gcccatcttt ccaaccagat tctgtacgta cgcccgaaga tttccaacga tttttagaaa
    21541 gagaatttta tgccagtaat cgtccaacaa tcattttatc ttatagttta agtcttggtc
    21601 ttgtcctatt tgtcatgacg agtctcattt tattcggggc ttcctttttc ttgtggatga
    21661 caagaaaaag ccaactttca tccattcata cattcaaaga gagtgcaaat ttgatgctga
    21721 atgttatggg aataggttcc atggcagcag cagttgtagg gtttatccac tttgacttta
    21781 tcttgatgct aagtgtccaa acaacgataa ctgtcttgct gcttttatgg gtttttgtca
    21841 aaacaagatt caaagataag cgtgtcgaat gacaagttta agcgatttat gcgacaatga
    21901 atgtgaaaaa aatgaaaaat aaagtagttt ttgaaaaatt tctgaaaaaa ttaaacttct
    21961 tagttgattc ttttcttttt tagtattaac gtaatagggt agttttttta aggaggaaaa
    22021 tcatgttaga gaaaacttta tacaatcaat tattttcacg ttctttctcg ctccctgtcg
    22081 aagtaaatta ttgggacggt acaacgaaac aatacggaga tacggacact cctccccaaa
    22141 tcaaaatcaa tatccatgaa gaaatcccaa tgaaagagat tacaagtaac gcttctttgg
    22201 cactaggaga agcctatatg gatcatcgaa tcgagatcga gggaagtatc caagcattga
    22261 tcaacgatgc ttatcagcaa gcaaacagct ttttacgagg aaaagattat ctaaaatggc
    22321 tgccaaagaa agaaaaacat acgaaacaaa aaaacaaaga agatatccat gcgcattatg
    22381 acttaggtaa cgacttttat aaactttggc tagatccaac tttgacttat tcttgtgctt
    22441 atttcaatac acctgaagat acgttggaac aagcacaaat caataaagtc catcatatct
    22501 tagacaaact ctttatcaaa gaaggcgaaa cgttgcttga tatcggttgt ggctggggaa
    22561 cattgatgtt cactgctacc aaagagtata atgtcaaggc aactgggatc acactaagtg
    22621 aagaacaata cgatttgatt accaaaagaa taaaagaaga acatttagaa gataaatgcc
    22681 gtgtattatt aatggattac cgcgaactaa aaggcgaaac gtttgatcat atcacaagtg
    22741 taggtatgtt cgaacatgta ggttctgaaa atcttgaagg ttatttcaaa gtggtaaaag
    22801 atttattgaa accaaaagga acagctttga tccatggaat cagccgacaa caaggcggtg
    22861 cgacaaatgc ttggatcaat aaatatattt tccctggcgg ttatgtccct ggtgttactg
    22921 aattagttga taatattaca aaaaacgatt tgcaactgat tgatttggaa agcttacgtc
    22981 gtgactacca attgacatta gaacattgga caaagaattt tcatcaagtc caagatcaag
    23041 tcacgaaaga aatgggtgat tccttctatc gaatgtggga tctatattta caagcttgtg
    23101 cagcttcatt tgaatcaagt aatatcgatg tgattcaata tttgcttgtt caacctggaa
    23161 acaatgacat cccaatgcat cgtgcataat tgaggcaaaa gtactgttta aagactattt
    23221 aaaaagaagc taagttttat gatgctccag aagtgaactt ttttgtctaa cttctaggat
    23281 tgtctctaaa gcttagtttc tttttcttta tattttcata ataaaagttt ggttctttaa
    23341 tttttaaaca tgacagaaaa ttttttcttc gttatacttg taatagaata ctattttata
    23401 acaaagggga tcgaatcaat gaaaaaaact gttatttata ctagtttatt tgcagctttg
    23461 tttttagctg cttgtcaatc aaataccaat caaggcacat ctgggaatac gtcttccagt
    23521 agcgaacagc gctcttcaca ggtatcggac tcctcaacaa aagcaagcac atcttcgtct
    23581 agccagacaa aaagttctag tgaagcaagt actcagtcag atatcaaagt gtctgcagct
    23641 cgtgcgatcg aattgttcca agataaatac ccagatactg caattactag tttggaatta
    23701 gatagtgatt ggggatctta cttctacaag atagaaggtg tcgatgatca aaaagaatac
    23761 gaagcaagaa ttgatgctca aaatgaaaaa atggagacag agaatccaga aactctagat
    23821 cgagatgaac aaaatggtca aaagaaaaaa gaagatggtc tggatgttga taaattgatc
    23881 acgattgagg aagcagcaaa aatcgccgtc gacaaagtag gaagcggtac ggcaacagat
    23941 tgggatttgg ataaagattt aggtactact tattgggaag tcaaagtaaa agacggcaat
    24001 caaagtacat cagtcaagat caatagccaa acaggcgaag tactgtcaac tgaacaagat
    24061 gattaagaat ttcttcggaa aacaagagtt gatttttctt ttagtcatga tacactagac
    24121 aaaataactt gtttgaagga gcgatttact tgagtttaga aacgaccttt gccaatcata
    24181 tctttgccaa tcctttgatg aatgcatctg gtgtccactg catgactacc caggaattag
    24241 atgaactggc tcattcagaa gcaggagcat ttatcactaa gagctgtacg atcaatgaac
    24301 gaaaaggaaa tcccgaacca cgctattttg atgttccttt agggagtatc aattctatgg
    24361 gacttccaaa cttaggtttt tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc
    24421 aggaaaacca aaatcaaccg ttattttttt ccattgccgg gatgagtgtc caggaaaact
    24481 tggaaatgct tgagaaaata gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat
    24541 cttgtcccaa tgtgcctgga aaaccacaac tagcttacga ttttgaggcc acttatgaaa
    24601 cactgaaaga agtattcagc atcttttcta agccgctagg aatcaaattg cctccttatt
    24661 ttgattttgc tcattttgat cagatggctg atatcttgaa tcagtttcca ttgacctatg
    24721 tcaatgctat caacagtgtg ggcaatggtt tgtatatcga tacagaacaa gaagcagtag
    24781 tcatcaaacc aaaagaaggg ttcggcggca ttggcggaga gtatatcaag ccgactgctt
    24841 tggcgaatgt tcgcgctttt tatacacgtt tgaaaccaga aatccaaatc attggtacag
    24901 gtgggattcg gacaggacaa gatgcatttg aacatctgct atgtggcgca agcatgttac
    24961 agattggtac cgagcttcat aaagaagggc cggaaatttt ttctagaatc ataaaagaat
    25021 taacgcagat tatgtcagaa aaaggatata cgtcaattga cgaatttaaa ggcaaattac
    25081 gcaccatttc atagcaaaga gacgaaggtc atgattgatc ttcgtctttt tttataaaaa
    25141 acactcgtct gttcattcct gtgcaagcgt actcattgta tgttagacga acttgtggga
    25201 aaataacaga ggcaaaaagg aggataatat gaatgatgca acagaattag caaaagagct
    25261 taaagaaaaa gaatttagtt ttcaagaact agttacggat atacagaaaa aaataaagaa
    25321 gcaaaatcat gaattgaatg cgtttgtcgc gcttgaacca ttcgagagta attcccacga
    25381 gctattgatt ccccagtcag aaaaagggcc attggctggt atcccatttc ctttaaaaat
    25441 gctcggtcaa gaaaaaaagg gatggctagc tacttcagga tctcgtttat ttgaaacaca
    25501 ccgagcttct catacatcta attatgtgcg gcaagcagaa gcgataggtc tagttccttt
    25561 tggacaaacc aatgcgccag agtttggttt caaaaatatt acagacccag tcatctatgg
    25621 cccagcaaga aacccttgga accttgaatg tacaccgggc ggatcaagtg gaggagctgc
    25681 tgctgcagtt tcatcaggaa tcgttccttt agctggtgct agtgatggcg gtggttctat
    25741 tagaataccc gcttcgtttt gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc
    25801 agttggtcca tatgcttgga gaggatggca aggagctgct attgatttcg gcttgacagt
    25861 ttctatgaga gacacggagg ctttatttta tgggatgaga agtatccatt ccggtgcgcc
    25921 atatcaagta tcgccagttg agtggcaaac acatccaaga aaaaaacggt tgaagatagc
    25981 tttttgtgtt gattcaccga tccactcaca gattagtgaa gaggcagtac ttgctgtaaa
    26041 aaaagctgta gatttccttg gaaaagaagg gcatgatttg acagagattc cttacccact
    26101 agatggtcgt aaactgatca cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat
    26161 gatccgctcg attgaaacag gcatccagcg agctgtcaga aaagaagaac ttgaacccat
    26221 ttcttggact ttgttccaat atggtcagaa gctctctgcc gctacttaca tcgattctct
    26281 gcatgtatgg gatgaagcag caattgtcat ggaaaaccta catcaagaat acgatctatt
    26341 cctttcacca acgactgcat ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc
    26401 gataagagca cagatggaac acatcagtga ttgttctgaa gtagaaggtt tagacgttgt
    26461 ttcttccatg tttgaggaga gcttgaagat cacaccttat acacagttgg ctaatctgac
    26521 tggacaacca gcaatcagct tgcctactca tttgacaaaa gaaaacatgc ctctaggaat
    26581 ccaatttatg gctgccagag gaagagaaga tttgctattt caaatcggct atctatttga
    26641 agcaaatcat cagttccatt taccaaatcc atggaaatag cagaaacaag gagaagaaga
    26701 atgaagaaaa aaagattgtt tgctctaata actagtgcct tttttatttt aagcgcttgc
    26761 ggtacagctg ccgctaatca ggaagataac agctggagta atgtagaaaa aaagaaagaa
    26821 ttagtagtag cgacttctgg cacactgttt cccgcatctt attataatga tcaaaatgaa
    26881 ttagttggtt atgatgtaga tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc
    26941 tcctttaaag aatacaacgt ggatggacaa atcacttctg tttcaaaaag agaatcagat
    27001 tttgctgcga acgattttgg tatcacaaaa gaaagagaaa aaaaattctc cctttcagag
    27061 actttcaaat attcatttga cagtatgatc gtacgaaaaa aagatgattc aggaatccac
    27121 tcacttgaag atcttaaagg gaaaaaagca gctggcgaac ccaatactag ctatatgcgt
    27181 ttagcggaaa aacacggagc taaattagtc acatatgaca atgccacgaa tgatcagtat
    27241 ttaagcgatg tagcaaatgg tcgaacagat gttattctaa atgattatta tctgcagaaa
    27301 atggccgtat ctgctttacc agatatccct gtaaaaatac tggagaacgt ttatttcaat
    27361 gaaaacgaaa gtggtttttt attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat
    27421 ggcgtattaa aagagatgaa agaagatggg acgacaaaga aaatatctga aaaatatttt
    27481 caaactgatg tttcagtcaa accgaaagaa acgatggctg agtcggtgag tgagtgatgt
    27541 actttcctct aattgatttt tccctcatgt ggacttcact tcctttcgta ctgcaaggct
    27601 tggtatacac attagggatt ggcttcgtgt cgtttctttt aggaaatctg gtagggttgc
    27661 ttttgacagt tttaggtctt ttggattggc tgcctctgaa tgtatttatt cgtttttatt
    27721 tatcgttctt tagaggcatt cccgcactag tcctgctgtt tctgttatat tttgggttac
    27781 cttatcaatt aagtgcctta acggcttcag tcatctgctt tacgattacc agcagtgcat
    27841 ttattggtga aatctatcga ggatcactag caggcgtttc ttcaggtcag tgggacgctg
    27901 gtttagcttc tggtttttct ttctttgggg tattgaaata tatcgttttg ccgcaagctt
    27961 ttcgaatctc agtaccggca ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt
    28021 tagcagcaac aatcacagtg ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga
    28081 cattcgatta tttttctctc tatattttag ttgcactgat ttattgggtc atttgtatcg
    28141 ggatcgaaaa agtgcaacag tatttagaaa aacgttctat gcatcagtca atctgaaaaa
    28201 tagaaatggt gctagcgtgg ctggcaccat ttctattttt tgtttcttgt atattctgcc
    28261 tagtatttta aaaccatttc atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa
    28321 catgaagacc ccgctaacca tcgaaataga atcctcgtta taccaatatt gcatcgagca
    28381 aggcggcttg gttgtagaag aagtcacgat gcctgatgac caaggaattg tagatacgct
    28441 tagctgcttg acaaaatttg atggaagccg agaatggcga tgctatgagc tgaaagtgac
    28501 aaaagcagat tttcgctcta cagccaaact gtcatttgtt ggacattata attattttgt
    28561 tttaccaagt aaactatatg aagaagtaaa aactgaaatc cctacaggaa taggtgtttt
    28621 agtgtatcgt ccgtacacgg ttgaagagga gatgcctgcc tctggtacat ttctgattgc
    28681 gaaaaaagca gcaaagaaag agcttgctgt accggaagaa gctttgacaa accgcttcat
    28741 ggcttcttta ttcagggaag taagaaaagc aaagcaaatg gagcgaggcg taaaatattt
    28801 tccaacagat caattgtaca aagaattgaa aagacgttca gaaaatcaag atccattttc
    28861 taacgaacga tattatgaac ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt
    28921 gcaagaagaa gttatcgcgc ttcagcatga ttatgaatat ttgaggcaac aacagcagat
    28981 ccgtcggttg cctacagagc cattggagtg aaaaatatgt actatcctta tttaagagga
    29041 aaacaatttg acctattagc attaaaagaa gcactgtcgc gaggattgct ctccaataaa
    29101 atccaaccag tgatcgaacc agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta
    29161 tttcaaaaaa agcaccatcc aatcgctgtg atccaaaatc cccaagtagg acaattcaaa
    29221 ttattcgatc agcatgtgca cagttggaca gtcaaagaaa atagctctgt cgtccctgca
    29281 cagatcttaa cgccagaaaa tctcagtgaa gtactggatt cacctccagc gtttcttgtt
    29341 ttcgatggac agcactaccc aaaagataca gaggtgtgga aacagttggc aggagttgat
    29401 tcgaaatttt tgataccaga tactagtcgc tttcgcatct ggctgcccga aaacaaaatt
    29461 gtgatccgtg actcttttca aacgagaaag catgttgaaa gttatgcaga taaaacagat
    29521 gactttttta gtgatgacta tctttttttc cacgcagacg gatatattgg attttctgat
    29581 ttcacgatcg aaggtagccg ttatttcgat aaagggttcc ctagccgagc gcttgctatc
    29641 catctaacgt atattgatgc ttacggcaat atacgcgtga aacattttgt ctctgacagt
    29701 aacgactctg ctaaagacca agcattgaag tttcttgaag caggagataa aatgaaaaaa
    29761 tggatcatgc gtcaccatca tcaactcttg attacttcag gaatgattga attattggct
    29821 ctttaccagc aacaaaaatt ccctggactg ggagtgttga aaaagtggtc acttatgcat
    29881 catttggaac ttattagtca cctgctagat catccaaaag attggcttaa atattattca
    29941 aaagttcagg aactatatga agtgatccaa tgattagata atgtaaatga aaaaggaata
    30001 gaaaagagga aactggatgt atattcggca aacaaggaaa gaagaagtag aagaagtggt
    30061 agaaatcatt aatgccgcag cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa
    30121 cgggcagaaa ccaacaaaag aaacgatttt gaacgatatt gaaagaaaag aaagctatgt
    30181 attaatagtg gaagatcaaa ttgctggaac agctgcatta gtctcaagcg tggatcccgt
    30241 ttacacaaaa atagatggta gttggaaaga atcaactggt ccttatttat cgattcatcg
    30301 tgtcgcttta gcagaaagta ctcgaggaaa aaaactagca aaaccgttct tagaacattt
    30361 gttgacgatt gcagccagca aaaatatcca agatatccgt atcgatactt atccagctaa
    30421 tgaaccgatg gaaaagacca tctattctgc tggattcact tatcaaggga tgattgaatt
    30481 tccttttgaa cacggcgaaa gaaaagcata tcaaataatc atcaattgac tataaaatca
    30541 tctgagcaaa gataaagaca ttaacactac tgaaaaaaac aatcatatga tagccaagag
    30601 gttgtaacag aagtggccag cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa
    30661 atttttgtgg aattttagcg tattttacga aatagctgct ttctgaaact cccttcatcg
    30721 agaggtcgtg acatagcttt tgtcacgacc tctcggctta tcctacgagt attattcgat
    30781 acatttatat caataatcct ttttttattt tatctgcagc ttcttggaac gctccatcgt
    30841 ttgacacgac taaaagtgag gggatagctt tcaaacgttt caactgtgct aaatcttcta
    30901 cataaaccgc cagtctggct gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg
    30961 attgcaatgt ttctttagag atcgtaataa agataggacg gactaccgtc ccgaaatact
    31021 catataaatg ccaaaaacca tttgctgtca aaacggcgta acaatttcct actgtcagtt
    31081 tctttttaat ttctgcttta ctggaaccat atttatgttg agcatattgg tcccactctg
    31141 caaactcatt tcccttgatc atctgattga atgtattgtc agaaacaaaa taataatcct
    31201 cttgatcttt ttccccaggt cttggtgatc gattcgtgta agtaatgatc ttttgttccg
    31261 gctgaaaaat agcttctgcg agtgaagttt ttccagaacc agaaggaccg ataaatacat
    31321 agcaataatt cattgtcatt tctcctttga tgattgaaca agtgaaaaag ctttggaaaa
    31381 tatttccaaa gcttttaaaa gtaactttgc ttttttgtat attataccag caagccagtc
    31441 acaatagcac ttaaaaagct gactaaagtc gctgttagca aaattttcaa tccgtgtttt
    31501 gcgacaagat ttcctttttc ttcatttaat cccttcatcg caccagaaat gatcccgata
    31561 gaagagaagt tggcaaatga aacgaggaag acagatataa ttgctgttgt acgctcagta
    31621 aaatggaaat taccatttgc taattctgtc atagcaacaa attcatttgt aaccagttta
    31681 gtcgccatga tactaccggc atccactgct tctttccatg ggattccgct gatgaaggca
    31741 agaggggcaa agatgtaacc taggatctct tggaaagtga tgccgaatat cccgtggaag
    31801 atagcattga tcatggcaat caaagcaaca aaaccgataa gcatagcagc aaccgtgatc
    31861 gccacatgga aaccatcaag aatgtattct cccaacattt ggaaaaatgt ctgttctttg
    31921 ttttcttcaa tgatcagctc atcttctttt tcttctaata catagggatt tacaattgaa
    31981 gccagaatat aaccgccaaa taagttcaaa acaagggcag tgatcacata tttagaatcg
    32041 atcagtgcca tataagatcc gacgatcgac atagaaactg tagacatagc cgatacactc
    32101 atggtgaaca aacgtttctc agataggaag ggtaattcct tttttatgga aataaaaact
    32161 tccgattgtc ctaaaatagc agaagctact ccattataag attccaattt gcccatcccg
    32221 ttgattttac ttaatcctag accaacagct ttcataaata atggaagaat cttgatatag
    32281 cgtagaatac cgataatagc agaaataaat acaattggca tcaatacgga aagaaagaaa
    32341 ggtgcacttc ctttatttgc tacaccggca aaaacaaagt caacaccttg cccagcaaaa
    32401 gcaagaagat gatcaaacat ttttgccaat acagaaacaa ccgctgtacc aaaagttgta
    32461 cgtaataata cgaaaccaag aacaagctgt aaaacgaaca tcacaattag tggtttcaat
    32521 ttgattgctt ttttgttact gctgatcaaa aaagcaagcc ctaatgtgac aaataaacca
    32581 ataataccta ataaataact caaataatca ctcctattcc aaattccgtt ttattttacc
    32641 tgttttgcaa ataaaatact aatctttagt gaaattttca ttactttttt agagtgaaac
    32701 gcattcattt tccattagaa aataaagcga acaaaataaa aggtttaaaa agtgtaacgt
    32761 cttagtaaag tctataaaaa aacgaaacta tcgattaagc taatagtttc gttttcaaca
    32821 tttataagta aactttttct attggtaata tagattttcg gaagggtaga caggtgcgca
    32881 ggtaatatcg attcctagtt ttttcaatgt ttgttcatca tttttattga ccatcacagt
    32941 agagtgggct tgtgctccct caagttcagc tagtttatca taagcaactt gagcgattgg
    33001 attcgttact gcactgattg ataaagcgat caagacttca ttgatgctta gtgcatccaa
    33061 agaggaatga agtgtctttg atttcaatcc ttgtattgtt tcaagaacta atggtgacaa
    33121 taaaggaatg tcatctgcga tatgggctaa atgttttact gcatttaaga taactgccgc
    33181 tgacgcatcc atcaatgaac ttgtacgccc ggtaatgatg acttcatctg gtaattcgat
    33241 tgcaatcaca gcagaaggat cttttgtagg actttgcgct tgaatcttat ctgcatagtc
    33301 atgggcaggg actaccacgt ttcggtcttc aggacgtaaa ccgacttctt ccataatcag
    33361 tttgattcga ttaactgctt cttcgtcgat caatcctttt ttgaagtcgc attctgtttg
    33421 gaaataacga cggatgattt cttgtttaga ggcttcttgg acaacggtat catccacgat
    33481 cccaaatcct acacgattca cacccatgtc agtaggagat tgataaacag attctttacc
    33541 agtaattttt tcaataatac gtttgattac aggaaatgtc tcaacatccc gattatagtt
    33601 cacagctact ttattgtagg catcaaagtg gaaggaatcg atcatattga catcttttag
    33661 atcgactgtg gctgcttcat aagcaatgtt cagcggatgt ttcaacggaa cattccatac
    33721 tgggaaagtt tcgaacttgg agtaaccagc tgcatgtcct ttttggcttt catgatacag
    33781 ttggttcaag gaagtagcga gctttccact tcctgggcca ggagctgtca ctacaacgat
    33841 tggtttagtt gtttcaatat actcattttt tccaaaacca tcttctgaga cgattttttc
    33901 tacgttgact ggatagtctt cgatttctga gtgtttatag accttgatgt ttcgtctttc
    33961 tagtttattg ataaagactt tcgtggcagg ctgtccacta tagcgagtga taacgacact
    34021 gttgattaat aagccataac cacgtaattc atcgattaac cgcaagatat ccatatcata
    34081 agtaatccca taatcaccac ggatcttatt acgttcaata tctccagcat agacgcaaat
    34141 cagtatttca gcttgatctt tcaatttttg cagcaatttg attttcgcat cttcttcaaa
    34201 tcctggaagt acacgtttcg catgcttgtc gtcaactagc ttcccaccaa attctaaata
    34261 taatttgtca tagtggttca ctcgttccaa aatatacgct gactgctctt caatatattt
    34321 ttctgaatca aaaccaattt ttttcactag gttccctcct taagtactaa agcatttttt
    34381 catttttttg aggattcgtc aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg
    34441 gtttaaacca acttgtctag atagttattc attggtatga tagtttttga taaggaaggt
    34501 gctacatgaa aaaaagacag aaaaagaaaa acgcatataa acactatatc cgttcgattt
    34561 ttaccggtta tgaaagaatg cttgaagatc ccgaattgga acaattgacg tttacttatc
    34621 taaacgaaga aacgcagcta actcgtgatg agcatcagcg cattcatttc acaacaagag
    34681 atctgcctag taaataaaaa ataagataaa ggtcatcgga ttcgattctg tcctatcaga
    34741 tggaaagact agttgatcga aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg
    34801 gagcattgcc cgctcttttt tataacaatt ttttacagaa aatggtacta ttgaagtatt
    34861 aataagtgaa aaacagatga gtaagaggag gcaagtagta tgaaagagcc agatacaaat
    34921 gcaaattatg agccagacga actagaggag acgaatgcgg atcaggatac aggacaagaa
    34981 tcgtcttctt tttacgatat caaagaaaaa gcaagcatga atctttccca attattagaa
    35041 gacttacagg cttttgaaaa agctgtccgc gaagaagata tccctgagat ctaccgttta
    35101 tacaatggcc gattgaatga agaattaaaa agaagctcaa atgaaaatca cgagatcgat
    35161 caattgctga tgcgtaagat ccatgatcgt tttttacagg aatttccttt tatggaacaa
    35221 gtagaaaaca tctcgccaac gatgagctat tacaaaatcg gcacttatta ccatgatcgg
    35281 cccacggtcg gtattgatgc aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa
    35341 gagtgggaga aatattccca accggagtca acggactatg acaaaaaaat caatgagcta
    35401 gacgcaaagg tgatcactgc tcagacagaa attgaacgtt tagatgaaca aataaaagaa
    35461 atcaatcgac aaatgactga tttgaacgac aataaaggat tcttgaatcg taaaaaaatc
    35521 gaggaagaaa ttcaagaatt agagaagaag aagcaagtac tatctaatga aaaattaggc
    35581 tggcttcctt atattgagac gcctgaaaca atccagcagc aaaaagaagc attgaagcaa
    35641 gaagcaagag cagaccagct tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga
    35701 cgctatttcg gtagcaaaga gggattcggt caagcaatcc atgaattctt gatgaattat
    35761 cttggcaatg agaatcctaa taatcaatct aatgaaggag gttccgagta tgaatgaaca
    35821 cgatgaagca gaatggacaa aaaatgaaga acaaacagaa gatcatgaag aaacgaacac
    35881 ttcattggaa gaacaaacaa gtaatcctct ggatgacaca gaagaaatcc ctatgctaga
    35941 ggaaacaaaa atacacgaaa aagaaaaagt aactccgacg aatacgaata ctgcagaaaa
    36001 cacccatgct tacgaaataa ctgaaaatcc cgggtattta gaaggaaaag agcaagatca
    36061 tcaagatatc gtcagtttga ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag
    36121 aaaagatttg atcgaatcag attttccaca attattagaa tcatatgatc gttttatatt
    36181 gaatgaagaa ccaatctcca cgatcggaaa gacaagcctg atcgaatact tcacgtatga
    36241 attactgaaa ccgttgaatg atattggtct ggaacggtca aattcagctt atgacacatg
    36301 gaaaacaaga catttttcga tcaattatac gttgaatgga caaaacgaat tagtcttttc
    36361 ctttgtatta ccgaccatcg atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt
    36421 atcaccagag acaatggaaa tcaatgtcca agatgaccgg gtgctttctt tgatccgaca
    36481 ctggtcagtg gatcgagtat tctctgcagg gcagatcacg atattcaatc acaaattgaa
    36541 tcaattatta gcccatgcaa gaacacttgg ttttaccgtt aatcagacat tactagacaa
    36601 tacgaagcca cttcgtttga atcttcagag cgaatttgaa ttgacgaatg aagtattgga
    36661 tgatattttt atcgtggcaa tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac
    36721 tacttatcaa gtacgattag ataaaggaca gtctttaacg ataacaacaa acgaaaaaga
    36781 tcaaacagtc ttgtcgatct catctggaga ctacccacga tctgtcattg atttctttat
    36841 caattacgaa ttcttggtcc cattaatggt gagaaagtcc tgattggata agttggatta
    36901 ccagatgtca ttcagataat tctgttccaa aggacttgcg gcagttatcc agaataattg
    36961 tcacaagtct tttctgtatg tactaaatgg acgtgaataa cttgctgatg aaggagggat
    37021 ttcattagga atgtccacaa ataaaatagc acagcttagc ttattgtctg ctgcttgtgt
    37081 agcaggtagg atcgcttttc aatttattcc gaatttccag ccaatgactg ctattttttt
    37141 atttatagta ctttacttaa gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc
    37201 gatcagcagt ttttattttg gtgttggacc atgggtcatc ggccaatgga tcagctatac
    37261 tgttgttctg agtttgtttt caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg
    37321 gttaaaggga gtctgttttt ttctggcggg catggtttac ggaataggta tgaccgtttt
    37381 tgatacgctg ttatatcgtt tgcctcaacc ttggatctat taccttcaag gggtgtcgtt
    37441 tgatttgatg cacagtatag gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa
    37501 acgtttttac aatcattcag gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa
    37561 tgagtgtcag tatactcatt ttgacaagtt gcagtacaac ctatacacaa tcggcttcca
    37621 accaaaagga ggaagtaaaa acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc
    37681 aaaacttttc ggaaaaagaa gtgttcttca aaaaaggcga tgatttactg agtattttga
    37741 aacgaaattt tgaagtcaaa gaagataacg gcttcatcac ttcgcttgaa gggcactcac
    37801 aggatgagaa aaatcaactc tattggatgt ttactgtgga cgggaaaagt gctactactg
    37861 gtgccaaaga gatcaaattg aatgatggac aatcggtcat tttcaatttg tctaaactat
    37921 aagtttcata aaaaactgtt aaagggcgaa tattgccata attcagtgag ttcagttgat
    37981 gaaagaagga aaataacatg gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg
    38041 ctctaggggc taatattcta gttgctatca gcaaatttgt cggctatgca atcagtggca
    38101 gtgccgccat gctaaacgaa agcatccaca gtatcgttga ttgcagcaat cagattttgc
    38161 tgttattcgg tgataaacaa gccaataaag gacagagcga gttgcatcaa tttggtgaag
    38221 gacgagcaaa atactttttc agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg
    38281 cacttggggt gatggaagct tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc
    38341 cgatcattgt tatagcaata ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg
    38401 tggcaatgaa agaaatcaaa gaattgaata ctgaaaaact ttccacgatg cgctttttgc
    38461 gcgaaagtcg acacagtgaa atactgatta tttttacgga agacttgtgt gctgtaatcg
    38521 gtttggtctt ggctttagca ggaacaatat tgacttatgc aaccgggatt gctgcatttg
    38581 atgcgatcag cggattgctg atcggtttct tgctgatggg agccgccatt ttcctagcaa
    38641 aagaatttta tagtctgatc atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca
    38701 agttagcttt tgaacgtcct gagatcagtc ggctgatcga tataaaaaca gttcatttaa
    38761 gtccaacgga gattttagtt gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag
    38821 cttactcggt catcaatgat attgaaaaaa atatgcgtca gtctcttcct gacaagaaga
    38881 tgtatatata cattgaaaca gataaatatg acccaaatta ttctcgtaaa taaaacgttt
    38941 attcatgaat tgaagcaaaa atgagaaaaa tataatcttg tttttaaata aaacggctac
    39001 aatttagcga atttatgtta caatgagtcc gctgtttatt tgttgtaatt aaaggagata
    39061 ttttaatgaa caaaaagaaa agtgcgccat ggcttcaagc tttgcatgca gtgatgccac
    39121 tttgtataag ctatatacca gtaggattag cttgcggagt attgttgcaa aaagttggat
    39181 ttgatcctct cttatcagga ctgttatcga ttctggtctt ttccggtggc gcgcagtttt
    39241 tagttgcatc tatgcttacg acgcaagcat catttgcaac gacattattg atggttttct
    39301 ttttagaatt acgctataca ttattaggag caagtcttgc cggttttatg aaaaaagaaa
    39361 agcggacgtt tttggctgtc ttttctcaat cactgaatga tgaaaactat gcggtgaact
    39421 acttaaagtt ttcaactgac ccttcctgga ataaaagaaa ggctttatat gtcaattggt
    39481 tctcaatgac tgcatgggcc ggtagcaata tgatcggtaa ttttttcggc tcggtgattc
    39541 gagtagatgc tgaccttgtc cattttgctt tgacggccat gttcattttc atgtttatca
    39601 tgcagatgaa aagcgcacta ctgatcttta caggtttatt ctcaggcgta ttaggggtcg
    39661 tattcatggt attattccaa aatactttcg gattgattgc agcaacagtc attgcttcat
    39721 ttgccggatt tatgctggag aaggcattca aaaaagaaaa agctaagaaa ctaagagacc
    39781 gcggtaaaga tgtcaatgag ccgctcttca acttcccgga acaggaggcc aatcaccatg
    39841 actaaactat atttgctact tttagttgct tgtctgttca tcgtggcata tatcccgcgc
    39901 ttgttcccga tgctttattt tactcatcga aaagtgccat cctggttcag tgactggatg
    39961 aaatatgtac cggtggcatt atttgcggcg ttagctttta aagatgtttt cattactcat
    40021 gaacatctgg atattgcttg gaatatcaaa atagctgcaa tgattctagt agcaggcgtg
    40081 gcttacaaaa cacgttcgat ggcgttgtca gttttgacag gacttgcgtc tgtctttttg
    40141 ctgtctatgc tttaaactgt tttattttat taaaaacaga gattgcgaca taagttgttc
    40201 aaactgatct atccgaactg catttgcaac agtcaattct ggatgcaagt ttattcgtag
    40261 ggataaaaaa gattagtgtt ggcttatgat gcaagctctt ttttatttta ggaattagag
    40321 agggatttgt ccttctatga ttttttgcta taatagggaa gatgtttatt ttatgaaaga
    40381 atagttgagg gaatttaaat gaataaaaaa ttgatgcaag gaacattttg gctaaccttt
    40441 gctaatcttc tatgtaaagt tttaggggta gtctatttga ttccctggct aagtatgatg
    40501 gggaacaatc aagatggtat gcttgctacg acattgtata atgttggcta tcttccttat
    40561 ggattgttcc tgatgcttgg tacagtcgga tttccaaatg cgattgcaaa aaaagtagct
    40621 gtagccacaa aagaaggaga taacgctgct tgtcggctga tttttagaag tacgatcaat
    40681 atcatgtttg tcatcggtat cgcctctgct gcactgatgt atttatttgc tcctttacta
    40741 gccggaatca gtccgattgc taacgttaat aatgggatac tagctatcag aagtttatgc
    40801 ccatctttga ttgctatccc aattcttagt gcaatgagag gatatttcca aggaaaaaat
    40861 gatctgcggc cttatggaac ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc
    40921 ttggctggta cttattactt gcgcgtattg actgacggaa ccatattaga agctgtattg
    40981 atcagtacag tcgcttcttt cttcggtggg ttagctgcga ttatccatat gtatatcgtc
    41041 ggacgcagaa aagacttctt cgaacttaaa gattttttga tttccagccg ttatttcgaa
    41101 agagaaaacc gatctgcctc tgtctctatc attcgggaaa cactaccgtt tatttttgtc
    41161 ggctcagtca ttactatcgt tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac
    41221 tttttccgtc cagagatcgc agatcagcaa ctggaattct tattcagccg tgcttctgtc
    41281 aatccaaata aattgacatt gatcctgatc tccatggtag gaacagtagc tataagcagc
    41341 ttgccaatat taagcacgat gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga
    41401 gatagttttt cgattgcgtt attgattctt cttccttcat tgactggaat gtctttatta
    41461 gctggaccac tatacacatt gttttttggc tatgatcctg aaagtgtcgg atatttccaa
    41521 atggctttgc tagcttcttt gtttttctct ttattcacga tcctatctac gatgcttcaa
    41581 tctttgaatc accatcgttt tgcgatccga ttaactgtag aagcaattat cctgaaagtc
    41641 atcttccaag taatcggatt aggattagtt ggcggatacg ggatgagctt atcaaatggc
    41701 ttagcattcg gtattgtctt tgttcgcggc tatcacttta tgtgcaaaga ataccgaata
    41761 gcacctttag caaagatcag caattttttc ttaaaaactt tccgctccac cctgattatg
    41821 cttgcagtat gttttgccgt tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa
    41881 agctatgcaa tgatttattg tgtggctgta ggaagtattg gcggcttagt atttttattt
    41941 tctcaattcg gaaaaaatgg gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc
    42001 aaagaatagg ttaactaatc gttttttgct gtcacttgaa aaacggcaac tcgtatgatt
    42061 acgcttgtcg tttttctatt ttccaatttt agtttcatat ctaatcttac ttatgatata
    42121 gttataaggt ctggaaaaat tctttgaaac gaggaaatta aacacatgaa acttgcagta
    42181 gttacagata gttcggcata tctgccggaa cgtatcaaga accatcccga cttattcgtt
    42241 attccaatcc ctttgattat ggatgggaaa atttataacg aaggaatcga tatcgaagcg
    42301 gatgaatatt atggactttt aaaaaacagt aaagattttc ctactacttc acaacctgtc
    42361 gtaggggaag ttttgggttt atatgaggaa ttgaaagaga aagggtatga cacgatttta
    42421 agtatccatc tttcttcagg gatttctggc tttgtcaaca cattatttgc gatgaaagat
    42481 gacatcagcg gagtaacggt cattccttat gactctaaga tcactagtat gccgatggga
    42541 cacatggtag aagctgcctt agacttaaat gatgaaggtc agtcccttga tgaaatactt
    42601 gcacatatcg atcgaatccg agataatacc tacgcttatc tgattgtaga tgatttgaac
    42661 aatttagtac gaggaggacg tttgacaaat ggtgcagcgc tgattggcag cttattaaaa
    42721 atcaaaccga tcctgacatt ttctgaaggg aaaattgttt tattcgaaaa aatccgttca
    42781 agtaaaaaag catttgctcg agctgaagaa attattggta gaagaaataa cgaaatacaa
    42841 ccgccagtca aactttacgt gatacatgca aataatttag aagtagcgat tgcggagaaa
    42901 gagaaattgc agaaaaaata tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc
    42961 attggtacac atttaggtga aaaagccatc ggcattgcca tttcagcgca ataattcctt
    43021 ttattcaaaa aacataccaa aaatattcca acatcatctt ggactttcta catgttacta
    43081 atgagcgtgt aaaagaacga gatggtgttt ttatttctat caatgaagct ctttttcttt
    43141 gcaatcctca cttcaatcct ctataatgtc gcatatagtt tagtaaatga gtaaactact
    43201 aatttactta tttactaaaa ataaaaggat gaggagttaa aataatggaa ataccaacaa
    43261 atttaaaaca taaaccagta atcgttgtag aagactatga taaagttgat ggaagaaatg
    43321 cattaaatac ggatgcaaaa gggctttcac tgggccttgc tcagtggaat gatcgtggaa
    43381 aagtcgatat ctcaggcaag gtatggcgac atactggaga aaaatggtca cgacagtcgg
    43441 aagaattacc aatcacacgt attttagatt tagcgatctt agctgcacaa ggaagtttat
    43501 acttccaaga tgcttatcgt tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca
    43561 tcattggatt acaagggaac cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg
    43621 atgaagacat cattttgtat tacgatacac tacaaaaaga cggagaactg attggggaac
    43681 gattccgtat tttaaaacgt cttttagatg agctaggata ttaatagaca gagatgatca
    43741 aaaggggaag agaagcatgg agaatttctc actaacagaa aaccgaacct tttcacggct
    43801 agaaaagcaa atgatctgga agaaaccgaa aagccatcgg acaagtgcag aagaatggcg
    43861 gatcgcctcc gaaatcaaag ggaattggca agatcctgaa atgaaaatca gtaacgtact
    43921 tttggaagga gatgccgggt cggggaagac acaattagcc aaagcactat ctgctgatct
    43981 gcaacttccc tatacaaaag tgacctgttt tgcagatatg gacaaatcag atgttttcgg
    44041 agccttatta cctgtagtag attctaataa ggaacaagac caagaattac tagaagctat
    44101 ttaccaaaca gatacacttg aagctgtact gacactgatc cagaaccatt acggcattga
    44161 tcctttttct gctaaagaaa aattagcaga gctagttcaa aggatcgaag ctgattatcc
    44221 agatgcaatc cattacagct attacccttc tgaaatcgtt cgagcgattg aaaaaggata
    44281 tttattagag attcaagagc cgactgtcat ccgagatgcc tctgttcttg tggcacttaa
    44341 ctcagcgctc gaaccaaatg ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc
    44401 agattgcgtc attgtgatca ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga
    44461 atctttaaga gatcggatgc aacatgcgga aaaaatggat cttcctgcct tagaagtcat
    44521 ggcagaacgt gcgatggcga aaactatgat ccaaaaacaa gaacttctct taaagatggc
    44581 agagattatc cgtttgttgg atgaaactgc aaaagctaac gccatcaaag gtgtagcagg
    44641 aatgcgttct tatttttatt gggcaaatac ctataagcaa ggacaagatt tactccagtc
    44701 gatttatcca aaagttttgt ataaattatc cactgattca gatgaattgg caattcttga
    44761 acaagctttg tctgacagtg gattgctact ggaacttcag gacatattga gaaaagaaaa
    44821 atggggtcat cctcaatctg agcatacaaa aggaagaacc attagcgccg aagaagcaaa
    44881 tgaacgaaac atcactgaaa atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt
    44941 gtctgctgaa gaaccaaatg agggagaaga gaaacaagaa gaaacaatag aaaaaaacga
    45001 gattcctcct caaatgcaaa aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga
    45061 acaacaaaca ggagatgatt ctcaagaaat gtctgcttct gacatggaag cacatgataa
    45121 ggaaatcaag aagcaactga ataaagaagc gcgacaaatc atgaaggaaa cgattcatga
    45181 aaaagaaggt ctcatcgttc accgaccagc tttccaagga aaaacgccgg aagcacgtga
    45241 gctacacatg caagtaatgc caatagtaga atcacttagc cggcaaattt tagagttact
    45301 ggataatgaa caaacagaga cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc
    45361 aagcaaagta gcatatggtg atttgagaaa ttttgacaaa aagaacccgc cacatgagca
    45421 accttcttta gcggtagctg tacggatcga tgaatctggg tcaatgatac gggatgatcg
    45481 gatcgaagcg gcaaaaaaag cagcgattgc cattgccgaa ttttctaaga aagtcgatat
    45541 cccattgttg atttacggag atacagcaga ccgttcgtca agagaaaaga cttctttgtt
    45601 ttcttataaa gaatttgaag acggatttca atggttaaat gaaaaattag tcactatgaa
    45661 accaaggcaa aacaatcgtg atggtgctgc acttcgttta gcagcagaaa aattaaacag
    45721 acaatccgca acaaccaaac tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc
    45781 ggattataca ggcaaaaaag caaaagaaga tatccagtct gttttgaaag aatatgaacg
    45841 tcaaggaatc ctatttgtct ccgcagctat tggccaagac aaagaagaaa tcaagtcgat
    45901 ctacggtgaa agtcgttttg tagatattac tgacttgaat gaatttccca agcaaatgat
    45961 tcaactgatt gcccgctatc tatgataaaa taaagctcaa cgaacgcact tagcagattc
    46021 gttgagcttt tcgtttctag ttaccggtaa caaggatact tctaaaatag aatcggttat
    46081 aatcaagagg gaccgttaaa ggagtgaaac gatatgatac aagaacaaaa atggtggaaa
    46141 gaagcagtag gctatcaaat ctatcctgct agtttcaaag atagcaatgg cgatggtcaa
    46201 ggagacatca atgggatccg tgaaaaactt aattatttga aagatcttgg tatcggcttt
    46261 atctggatca atccgatcta tcaatctcca tttgtcgata atggttatga cgtaagtgac
    46321 tatcaagata tagaagagag attcggaacg atggaagatt ttgatttatt gctaaaagaa
    46381 gcacatgaat tagggatcaa agtgattatg gatcttgtca tcaaccatag ttcggatcag
    46441 catcaatggt ttgaagaatc gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt
    46501 tgggtcgacg gggtagatgg caaagaaccg aataattgga catcgatttt cggcggttct
    46561 gcttgggagt attctcatga aactggacag tattatctgc atgtttttgc aaaagaacaa
    46621 ccagacttaa attgggaaag cgagaaattg aaagaagaac tattcaatat gatccgatgg
    46681 tggttggata aagggataga tggatttcgt ttagatgcga tttctcatgt aaaaaaagat
    46741 gaatattcag taaaagccac agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc
    46801 gaagaacatt tgaccgattt gaaacatgtt tttgaagagt acgatatcat gactgtcgga
    46861 gaagcaagtg gtgtcactgc agaagaagga ccacaatggg tagggaaaga cggttatttc
    46921 gatatgatat tcgaatttga tcatatccat atctggcagc aagaaaaaga agggcaatta
    46981 gatgtcctta aattgaaact tgcattaagc gcttggcaaa cttcattgga tggtatcgga
    47041 tggaacgctt tatatatgga aaaccatgat gttcctcgtg ccgtttcagt gtttggagat
    47101 actcgtcccg atttttgggc tatgtctgca aaagcaatcg ctatgatgta tttctttttg
    47161 caaggtacgc catttattta tcaaggacag gaaatcggaa tgacgaatat gccctttgaa
    47221 tcgatcgatc aagttgatgc agtagattcg aaaagacttt ataaaaggct gcttgcggaa
    47281 ggtaagacaa gagaagaagc attggatatc attcgtgaaa caacgagaga caacagcagg
    47341 acacccatgc aatggacttc ggaacaatat gctggttttt ctacacatga accttggctg
    47401 atcactaatc caaataccaa aacgatcaat gtagaacaac aagaatatga accagagtcg
    47461 gtcctgcaat tctataagaa catgatccgc attagacaaa ccaataaagg tctgatatac
    47521 ggttcttata aagaatatct tcatgaacat ccacaacttt atgtctatga aagatattta
    47581 gaagatgaac aatatcttat tatggtaaac ttaacagaat cacttgctga ctatgaactt
    47641 ccaaaagaag cagatcagtc ctggacatta ctcttgtcaa attcctctag cggagaattt
    47701 gaagctaaag gcatactagc accttatgaa gctcggttat ataaaacaaa caagtaaaac
    47761 ttcctcgtta aagttcatta gttggacttt gcgaggaagt ttttcagatt gctctgtcaa
    47821 ttactcattt caataattcg ctctaggacc accgatatat ttaggacgag agcgaagggc
    47881 tgtcacgtga gcttgtccaa gggttttcaa acgaggtctg acaggtactt ggacatgttt
    47941 gatatgcata ccgattgatg tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc
    48001 cacttcgaca ggatcattga actggtcaaa agcagcaaca gaacaagcac ctccagcatg
    48061 tagtgcagga acaacagaga caatttcgaa attttttgct tctgccactg ttcgttctac
    48121 tactaatgct cggttcaaat gttcacaacc ttggacagct agcgcaattt ctttaggatc
    48181 caacaactct tttaacgtac ggatgatcca ttgaccaact tccgcactgg aattttttcc
    48241 aatatgtcct ccaacgactt cgcttgtgct gcatcctaaa acaaaaagat cacctttttt
    48301 caagtgtgcc tcagccaata tgtcattaac tatttcagtc aattggtctt ttaattcttt
    48361 ttctgacaac ttcattttct aaaaccttct ttttcaatta atattgcttc cgtgcttgaa
    48421 tacgttgaag acttgcagtt ataggaaagg caagtcccat tccaatcaga ttttggaaga
    48481 tgtttcctgg tatagaagcc actccagccg gccaatcata taaaatccaa ccggcgatac
    48541 catagccgat gatcataact aagcttccta ataaaagccc taatccccac atacgagtag
    48601 aagatttgct gaaagaacca gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa
    48661 ctgcccactg cggatatcct gaaatcaaat cgatcaatag accactggaa gcaccaacaa
    48721 ctaatccacc cgttggacca taaagaaaag cagcggtata gatcccggcc tcgcataatg
    48781 tcacaaatcc attcgtagcc ggtacaggga tcaaaattgt taatgaaagg gcaactgtca
    48841 acgcaatcag catagcatag atcgttaatt gcttagtttt catttctcat tcctcctttt
    48901 tgaataccgc cagaccagac acttccggta tgatcgttca tcagcacgcc attagaaata
    48961 caatgggcaa caaatttttt actttctgct actgctttgg taaaatctgc ccctaacaca
    49021 agattcgctg ttattgcaga agaaaaggca caaccggccc cgtttactgt tgtagtgtcg
    49081 atttttttat gagaaaatac ctcataatga tcaattgaat agagaagatc cacagcttca
    49141 tctccagcca tccttgtgcc gcctttgatc acaatgtttt ttgttcctga agcagtgagt
    49201 tctttagcga gatggatcat ttctgttaac gaagagggaa gagcttgacc agaaagtaaa
    49261 gcagcttctg ccaaattagg cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc
    49321 tgcgaaatat acaattgatt gatcacagct tcagtttctt tgaatgccaa aacagggtct
    49381 aaaatgattg ggatattttg ttttgttttt atgaagtctc gaacaaccat gattgcttca
    49441 cttgaattca ataacccaat tttgatacca tctaatgaag tcattttatc aatcgaaact
    49501 aactgtcgtt taagcaattc caaagatata gattccagca taaatcgctc attaatatct
    49561 agtgccccta tagaagtcaa ggcgcttagt ccgaatagac caaaattctc aaaagttttt
    49621 aaatctgttt ggattcctcc accagcaaat ggatcagaac cgccaattgt caagattctt
    49681 ttcataacat tttcctccat gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc
    49741 caattggcat atttttatct catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa
    49801 tggatctttc tttccttaaa tagttaggac ttttgtgatt ttaattcttt ctcgatttga
    49861 agccgttgca ctttcattgt agctgttcgc gggattgcat caaaatcacg gatgataggg
    49921 acgttcaagc gaggaagttc atggacttgc tcccaccatc gattccaatc catttcttta
    49981 tcaggagcta aagcaataat cggttgtgga gaatgatttt tatcccttac aatcactact
    50041 tctgccaaaa aatctaacga atctaataaa aagtcttcaa tagctaatgt actattgatc
    50101 gtttcgatca aatccacttg ccgatctttc aaaaataggt ggccatgctt atccataaaa
    50161 ccgtaatctc cgctatccca ccaatcgcca taaacatttt cctggaaccg tgcatcttcc
    50221 ttgtaataag tcaaagcccg tcctttagac agtaattgta tatgaccatc tgtgttttca
    50281 ggtaggacat tcccaactga atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg
    50341 cccatatctc ttgcatcact tgttttcaaa ctctctagtg tatgagcctt aagaatcatt
    50401 ggtccgcatt cactttggcc atatacttga agaaataccg catcctgtgc catcgacgtt
    50461 cgcaaaaatg tcttcattgt ctggttgttt atagcatcaa aagtggagtg atagtatcgg
    50521 atacccgaaa aagcttctgg atgctcctta gcagtaaaac gccactgaac aaagttattc
    50581 ggatgggtct ctagtgcaat tggccggtga gcttccaaca tatgaacaac ttttgaactt
    50641 tgtgcgtttg ctaaaggcat cataggaaat cccatggaca tcaaagaaga gataccaata
    50701 ttgaatctgg aatgcactgg agagatgtga aaagcgatta atttcttttc cgaaattttt
    50761 gtgaaaactg ttttttgcca tttcgtccgc catcccatag aatgagcaga atgacaaata
    50821 agtttaggga taccagttgt accagaagta tgggtcatat aagaaatttc atttttgtct
    50881 aaaaatgatt gagaaacaga caaagcaggt tgttccatta aataaagaat agga
//
LOCUS       DAMEEU010000011        47981 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.011, whole genome shotgun sequence.
ACCESSION   DAMEEU010000011 DAMEEU010000000
VERSION     DAMEEU010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.011"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            644..1333
                     /locus_tag="PB779_000680"
     CDS             644..1333
                     /locus_tag="PB779_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0738223.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1320..2528
                     /locus_tag="PB779_000681"
     CDS             1320..2528
                     /locus_tag="PB779_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0738224.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2822..4093
                     /gene="serS"
                     /locus_tag="PB779_000682"
     CDS             2822..4093
                     /gene="serS"
                     /locus_tag="PB779_000682"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HDE0738225.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
     gene            complement(4642..6126)
                     /gene="guaB"
                     /locus_tag="PB779_000683"
     CDS             complement(4642..6126)
                     /gene="guaB"
                     /locus_tag="PB779_000683"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HDE0738226.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(6631..7326)
                     /locus_tag="PB779_000684"
     CDS             complement(6631..7326)
                     /locus_tag="PB779_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HDE0738227.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(7416..8516)
                     /gene="ychF"
                     /locus_tag="PB779_000685"
     CDS             complement(7416..8516)
                     /gene="ychF"
                     /locus_tag="PB779_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HDE0738228.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(8525..8716)
                     /locus_tag="PB779_000686"
     CDS             complement(8525..8716)
                     /locus_tag="PB779_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HDE0738229.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(8737..9627)
                     /locus_tag="PB779_000687"
     CDS             complement(8737..9627)
                     /locus_tag="PB779_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HDE0738230.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(9614..10381)
                     /locus_tag="PB779_000688"
     CDS             complement(9614..10381)
                     /locus_tag="PB779_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDE0738231.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(10393..11106)
                     /gene="rsmG"
                     /locus_tag="PB779_000689"
     CDS             complement(10393..11106)
                     /gene="rsmG"
                     /locus_tag="PB779_000689"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HDE0738232.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(11338..13239)
                     /gene="mnmG"
                     /locus_tag="PB779_000690"
     CDS             complement(11338..13239)
                     /gene="mnmG"
                     /locus_tag="PB779_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HDE0738233.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(13256..14653)
                     /gene="mnmE"
                     /locus_tag="PB779_000691"
     CDS             complement(13256..14653)
                     /gene="mnmE"
                     /locus_tag="PB779_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HDE0738234.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            14952..15335
                     /locus_tag="PB779_000692"
     CDS             14952..15335
                     /locus_tag="PB779_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738235.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(15503..16261)
                     /locus_tag="PB779_000693"
     CDS             complement(15503..16261)
                     /locus_tag="PB779_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HDE0738236.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(16279..17097)
                     /locus_tag="PB779_000694"
     CDS             complement(16279..17097)
                     /locus_tag="PB779_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDE0738237.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(17094..17450)
                     /gene="rnpA"
                     /locus_tag="PB779_000695"
     CDS             complement(17094..17450)
                     /gene="rnpA"
                     /locus_tag="PB779_000695"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HDE0738238.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(17568..17702)
                     /gene="rpmH"
                     /locus_tag="PB779_000696"
     CDS             complement(17568..17702)
                     /gene="rpmH"
                     /locus_tag="PB779_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HDE0738239.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            18226..19560
                     /gene="dnaA"
                     /locus_tag="PB779_000697"
     CDS             18226..19560
                     /gene="dnaA"
                     /locus_tag="PB779_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HDE0738240.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDIKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            19758..20888
                     /gene="dnaN"
                     /locus_tag="PB779_000698"
     CDS             19758..20888
                     /gene="dnaN"
                     /locus_tag="PB779_000698"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HDE0738241.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            21117..21359
                     /gene="yaaA"
                     /locus_tag="PB779_000699"
     CDS             21117..21359
                     /gene="yaaA"
                     /locus_tag="PB779_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HDE0738242.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            21346..22470
                     /gene="recF"
                     /locus_tag="PB779_000700"
     CDS             21346..22470
                     /gene="recF"
                     /locus_tag="PB779_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HDE0738243.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQIRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDSRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            22467..24413
                     /gene="gyrB"
                     /locus_tag="PB779_000701"
     CDS             22467..24413
                     /gene="gyrB"
                     /locus_tag="PB779_000701"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HDE0738244.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            24433..26904
                     /gene="gyrA"
                     /locus_tag="PB779_000702"
     CDS             24433..26904
                     /gene="gyrA"
                     /locus_tag="PB779_000702"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HDE0738245.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            27140..27439
                     /locus_tag="PB779_000703"
     CDS             27140..27439
                     /locus_tag="PB779_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HDE0738246.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            27489..28001
                     /gene="ssb"
                     /locus_tag="PB779_000704"
     CDS             27489..28001
                     /gene="ssb"
                     /locus_tag="PB779_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDE0738247.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            28027..28263
                     /locus_tag="PB779_000705"
     CDS             28027..28263
                     /locus_tag="PB779_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HDE0738248.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            28406..30379
                     /locus_tag="PB779_000706"
     CDS             28406..30379
                     /locus_tag="PB779_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HDE0738249.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            30385..30837
                     /gene="rplI"
                     /locus_tag="PB779_000707"
     CDS             30385..30837
                     /gene="rplI"
                     /locus_tag="PB779_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HDE0738250.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            31111..32478
                     /gene="dnaB"
                     /locus_tag="PB779_000708"
     CDS             31111..32478
                     /gene="dnaB"
                     /locus_tag="PB779_000708"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HDE0738251.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            33258..34550
                     /locus_tag="PB779_000709"
     CDS             33258..34550
                     /locus_tag="PB779_000709"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HDE0738252.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
     gene            35337..36200
                     /locus_tag="PB779_000710"
     CDS             35337..36200
                     /locus_tag="PB779_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDE0738253.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(36329..37951)
                     /locus_tag="PB779_000711"
     CDS             complement(36329..37951)
                     /locus_tag="PB779_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738254.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            38200..38721
                     /locus_tag="PB779_000712"
     CDS             38200..38721
                     /locus_tag="PB779_000712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HDE0738255.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(38907..40637)
                     /gene="spxB"
                     /locus_tag="PB779_000713"
     CDS             complement(38907..40637)
                     /gene="spxB"
                     /locus_tag="PB779_000713"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HDE0738256.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            40802..41620
                     /locus_tag="PB779_000714"
     CDS             40802..41620
                     /locus_tag="PB779_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HDE0738257.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKHHFAVFGVMSGFIIMMILDVALG"
     gene            complement(41723..41920)
                     /locus_tag="PB779_000715"
     CDS             complement(41723..41920)
                     /locus_tag="PB779_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738258.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            42089..42667
                     /locus_tag="PB779_000716"
     CDS             42089..42667
                     /locus_tag="PB779_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDE0738259.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            42762..42899
                     /locus_tag="PB779_000717"
     CDS             42762..42899
                     /locus_tag="PB779_000717"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738260.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(43712..44215)
                     /locus_tag="PB779_000718"
     CDS             complement(43712..44215)
                     /locus_tag="PB779_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDE0738261.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            44574..45599
                     /locus_tag="PB779_000719"
     CDS             44574..45599
                     /locus_tag="PB779_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDE0738262.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            45922..46800
                     /locus_tag="PB779_000720"
     CDS             45922..46800
                     /locus_tag="PB779_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HDE0738263.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            47276..47392
                     /locus_tag="PB779_000721"
     CDS             47276..47392
                     /locus_tag="PB779_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDE0738264.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
BASE COUNT        14718 a         9032 c         9390 g        14841 t
ORIGIN      
        1 ctacacattt ggtttgtctt actttgttca gttttcaaag gtctacttca tcaggagtgt
       61 ttcccgattc gtttttggct gccgtagcaa cttttatatc atatcagaga gacaagtaat
      121 tgtcaactct tttttaaaag ttttttcgat ttcgtttttc gaaatcttcc agcaactcat
      181 ttatcataac ttatcgtttg ttatttgtca agaacttttt tgaagttttt ttcgatagaa
      241 tcaagcttcg caagtggttc ttttttaacg actcagttat cttatcatgt catttccaac
      301 atgtcaacaa cttatttttt attatttaat aagttattgg tgttcttttg aacaaataat
      361 aatatatcaa catcacatgt gaaagtcaat aagaaaatgc ttatttatca acatttctag
      421 cttacatgat cattggttag ttctggtcct ttttcgttcg tctttataac tccgagagac
      481 gtaaaatcct tttgttttca gtttaatgtt catgttcttg tcttattcac accaactaga
      541 tgtctcacct tctaaaattt tccttaacaa agtgctgctt ttatctattt ctgctttttt
      601 ttgctagaat aatagtaaca atatgactct ggaggattta tttatgaaaa ttttgattgc
      661 tgacgatgat aaagaaatcg ttgaattatt aagtatctat gttcacaatg aggggtatga
      721 agcagtaaag gcttatgatg ggaaagaagc attatctaaa atcagaacaa tccctgatat
      781 tgaattactt attttagata tcatgatgcc tgagatggat gggatgcaag tagtgaaaga
      841 gctacgaaaa gaatcccaaa taccaatcat tatgctgaca gcaaaaacta ctgatatgga
      901 taagatcaaa ggactggtcg ctggtgcaga tgattatgtg accaagccat ttaatccgtt
      961 agaagtaatg gctagagtaa agtctttatt acggcgtaca aaaatgcaga ttgccccaga
     1021 tcagcctgat gtattagaag taaatgcatt aatcatcaat aaagactctc atgaagttaa
     1081 aacaatcgat gggaaagaaa tccagttaac agctttggaa ttcggtatcc tctacttgct
     1141 tgctagtcat cctaatcgag tatttagcgc ggatgaaatt tttgagcgtg tttggaaaca
     1201 agaaagtatt gtctctgcta aaactgtcat ggttcacgtt agtcatttaa gagataagat
     1261 tgaagaagca actggtggtg aaaaagtcat tcaaaccgtt tggggagtgg gctataaaat
     1321 tgacgcaaga tagtaaacga gcaactgaaa aacgccgtcg gatcaatttg acttcaaaag
     1381 aaatcagcga attgttagcg gaaggaatca tcacgattat ccttttgctt ctattaaatg
     1441 tttctattct ggttgttatc agttcggtga tcaacagttc accttctttg acgaatgcga
     1501 tttgggattc aaagaatatt tttgcagaac gattgaacac tgatttgttc tggaacggcc
     1561 ggaattttat tattcccttt ttctttctat tagatattgg tgttttgtat tggcgcttga
     1621 ttcgaagata tcgccaaatg caattgcggc atatcatcag cgaacttcac tacatcgcaa
     1681 acggaaatta tgatcatcgt atcccttttg aactgagtgg tgacttaagc cgagtggtaa
     1741 caagtatcaa tggattggtg gatagtaccg tagcagcgat tgaagacgaa cgtaaaatcg
     1801 aaaaatcaaa agatgaattg atcacgaatg tcagtcatga tatccgtacc ccactcacgt
     1861 ccatcattgg atacctagga ctgatagaag atggccagta tcactcagaa gaagatcttt
     1921 taaagtatac gcatactgct tatatcaaag caaagcagat gaaatcttta gtggacgact
     1981 tatttgaata cactaaggta cgccagcctg ctgtcccggt gaatttttct gcctttgaca
     2041 tgatccagtt gatcgaacag ttagcagctg attttgagtt ggaagcttct aaaaaaaata
     2101 tccaaatact tgttcaatca aaagtagact cccttatcat ggatggcgat accgaaaaac
     2161 ttgtacgtgt cttcaataat cttttgacga atgcgttgaa atacggaaaa ggagcaacga
     2221 agatcgtaat cgaagtagaa cgtatcggtt cagaagttgt tgcaacagtc aaaaataacg
     2281 gagcaatgat cccacaacag gcaatcgata atctattcga ccgtttttat cgtgtagaag
     2341 aatctcgttc acaagcaact ggaggaactg gacttggttt agcaatcgct caaagcattg
     2401 tggctttgca cggcggatac atttatgcaa aatcagataa gcaatggact tctttcatca
     2461 tgcaccttcc aatcaagaaa aatgaaaaat tacctattga tacacaggaa gttattgacg
     2521 aaagctgaaa tattcgctat tcttattaca attattagaa taaatgaaaa acacagaacc
     2581 cagtacactt tattcttttt cagagagctg atggcaggtg taaatcagca aaggataatt
     2641 tggaagttcc agttcgttta cgtgcccttt cgaaataaga aaggtcggtt caacagccgt
     2701 tatgtgttca acaagtgcag ctgacgctga acttgggtgg taccgcgaat ttcagactga
     2761 ttcgtcccaa gaataatggg atggatcagt ctttttttat tttcaaaaag gaggaaatca
     2821 tatgttagat gtaaaaatga tgcgacaaaa tattgaagaa gtacaagaaa aattgatgac
     2881 tcggggcgta aaaaaagaaa cattagctga attcatggaa ctagatgaaa atcgtcgtaa
     2941 gctactagtc aaaagtgaag aattaaaaaa atatcgaaat gatgtttctg ctgagatcgc
     3001 ccaattgaag cgtgcaaaag aagatgcttc tgctaaaatc gctgaaatga aagaagtcgg
     3061 tggcaacatc aaagcattgg atactgaaat tgctgaagtg gatgaaaaat tgaaacaaat
     3121 tgcaactact ttgccaaacc ttccccatga ttctgtgcca gttggaacag atgaagagga
     3181 caatgtagaa atccgtcgtt ggagcgaacc acgtacattt gcttttgaac caaaaccaca
     3241 ctgggaaatt gcagaaaatc ttgatatttt agattttgaa cgtggcgcaa aagtagccgg
     3301 tagccgtttt gtctattaca aaggattagg tgctcgatta gaacgtgctg tctacaactt
     3361 catgcttgat cagcatattt acgaacacgg ctatactgaa atgatcactc cttatatcgt
     3421 caacagtaaa gcgatgtttg gtacgggaca atttccaaaa ttcaaagaag atgttttcca
     3481 attggagaat actgatctaa cattaatccc aacagctgaa gtaccattaa ctaactatta
     3541 taatgatgaa attttagatg gtgcagattt acctatttat ttcactgcac taagccctgc
     3601 ttttcgttct gaagccggaa gtgctggtcg ggatacacga ggactgattc gtcttcacca
     3661 attcaataaa gtagaaatgg tcaaattttc ggatgtagag cattcttacg aagaattgga
     3721 aaaaatgaca gctgatgcag aagatatctt gaaaaaattg catttgcctt atcgtgtgat
     3781 ggccttatca actggagaca tgggcttttc tgcagctaaa acttatgact tagaagtatg
     3841 gatacctgca caagatactt atcgtgaaat cagttcttgt tctaactgtg aagatttcca
     3901 agcacgccgc gcaatgatcc gttatcgcga taatgatgga aaaatccact atactcatac
     3961 tctgaatggt tcaggacttg cagttggccg tacagtagct gccattttgg aaaactacca
     4021 aaatgaagat ggttctgtca cagttccaga agcgctcgtt ccttatatgg ggaatctgaa
     4081 agttattaaa taaagaggct gtgaaaaagc cgcttagttt cgagtattaa gaaaaatttt
     4141 gtgaaaatgg ctttccacat ttttgcataa attggactta ataccgagaa actggctttt
     4201 gaacaccatt tatcgagagg ttgtgaaatc agcgaattaa cctgagtatt agagaaaaaa
     4261 atggaaaaat agtccctcat attttaccgt ttgttgaact aataccgagg gtcagctgat
     4321 tgaacaccgt ttagtggaga ggtcgtaagc ctacccccca gctcctagtt acaaggacaa
     4381 attcaaaaaa cagctcttca tattttatga atgttgtact tgtgattcgg aggtggcaag
     4441 ggaacactgt ttattcaaaa agaggctggg acagaagcgt ttaactccaa gaaataagaa
     4501 gaaattcacg aaaattgctt ttcaaatttt tgtgaatttc ttcttatttc cgaaggagtt
     4561 gcttctactt ccgccgttta tacgtgttta gagcgtgaga caaaagtgtt ctttactttt
     4621 gtcccacgct ctttaatgtt tttaagattc aactgaatag tttggtgctt cttttgtgat
     4681 ttgtacatca tgagggtgtg attcttttaa tccactgccg ctcatttgga taaattgcgc
     4741 ttcatcacgt aattgctgta gattggctgc cccaacataa cccattcctg aacgcaaacc
     4801 gccgatcatt tggaaaataa tatctgcaac acttccttta taagcaaccc gaccttcgat
     4861 tccttctggt actaatttat ttgcttcatt gacactacct tggaagtaac ggtcttttga
     4921 acctttttcc atcgcgccta atgagcccat acctcggtat gttttgaatc gacgtccttg
     4981 gaagatttcg aattcacctg gtgattcatc tgtccctgcc aacatacttc ctagcatcac
     5041 tgcatgtccg ccggcagcta atgctttgac gatgtcacca gaatatttga tccctccgtc
     5101 tgcaataatc gctttgccat attgacgagc aactgatgct gcatcataaa tagctgtgag
     5161 ctgaggtaca cctacaccgg ctaccacacg tgtcgtacaa atcgatcctg gtccgatacc
     5221 aacttttacg acatctacac ctgcatcata taaagctttt gtcgcttcag ccgtcgcaac
     5281 gtttcctgca atcaatgttg catctgcaaa agttgaacgg atttcttgaa tttttcggat
     5341 cacacctgca ctatgtccat gagctgtatc gatgatgatt gcatctgccc ctgcttctaa
     5401 taaagcattc gcacgctcaa atgtatcgct tgttacacca acggctgctg ctacaagcaa
     5461 tcgaccatgt tcatcttttg ctgcatttgg aaattcgatc actttctcga tgtctttgat
     5521 cgtgatcaat ccgcttaaac gaccttcgtt atctacgatt ggtaattttt cgattttatg
     5581 tttttgcaaa atcttttctg catcttttag agaggtacct actggggcag tcactaagtt
     5641 gtcttttgtc atcacatcag caatcggcat gtgataatct gttacaaaac gcatgtcgcg
     5701 gtttgtaatt atccctacca attttctgtt ttcaagtgtt tcaacgattg gcacaccact
     5761 gatacgatat ttgctcatca attcttctgc gtctgctaca agatgctgcg gcgttaagaa
     5821 gaacggatca atgattacgc cactttcaga acgtttgact tttcttactt catccgcttg
     5881 ctggctgatc gtcatgtttt tatggatcac acctagtccg ccttgtcttg ccatagcaat
     5941 ggccatcttg ctgtcggtaa cagtatccat acttgcactg atgattggaa tattcaactt
     6001 aatattttta gctaattgta cgctcatatc cacttcgttt ggtaacacgt gactttctgc
     6061 tggtatcaat aagacatcat caaaagtaaa tccttttttc gtgaactttg tttcccagtt
     6121 ggacattttt agtaccactc ctctaattta gtttatctat taaaataatt gattttttca
     6181 tttaagtcaa tgatctactt ggaatcaagt tagctttctc atagaatacc aatataaagc
     6241 gtttacatct gtgtgtatta aaagagattg taaaaaagct gtcctgcatc aagtaataag
     6301 aacagccaat caaaaacagc ttctcatgtt tttgaattgg ttgggtttat taccgcagat
     6361 gcaaactttt gaacaccgtt tagtggagag gctgtgaaaa agctgcttag tttcgagtag
     6421 taagaaaaat tttgtgaaaa tggctttcca catttttgca taaattggac ttaataccga
     6481 gaaactggct tttgaacacc gtttatcgta aaaagggact gtgacaagac ttttgtcaca
     6541 gtcccttact attatttaac tatggataaa caaaatgagg ttctttacta cccctagata
     6601 tctagcaaaa tagctgatct ttttgctagt ttatcttctt gggacggata aacttccaat
     6661 aatcccgtat tttttcttca agtagtaacg gattgctaaa gcagttgccc cgataatgat
     6721 aactactact ggatctaata ctggattgat aactggtggc aatagtgttg tcgcagaaaa
     6781 cagtacgacc caaagaagtg tcgttccacc taggataagc aatgtcttac ccattcctgg
     6841 tttcttgctt cgatctgctc cgggatattc atattgatag atgtatttgt acatcatata
     6901 aaagacccag ccaccgattg cagaacctag aacgagtgta gaaaagccat aagctggcgt
     6961 tgttccacgt gaaaacaatc cggtaatcgc aatcatgata cttaatagac caagcaacag
     7021 caacgtatta tctaaccaca tcaataaagg ggtggatgaa ttttttactt ctgctggctt
     7081 attgatgatt gcttccgttc tttcagagac tgtcccaaac aattgacggg ctgttcttcc
     7141 gcctttttgt tctgcaacta aagtaggcag aatgtcatga agggctttta ctttttcttc
     7201 ttcagacaaa ttcgctgctt ctaaagattt tttcaaatca aaaatgtact gttgatttct
     7261 tttggttaat tttgtttcta aactattgtt ttcttttacg attgctcgta attgttctgg
     7321 ttccattatc taatagtcct ccttagccgt tccttttctc aacggtcgtc acaaaagaca
     7381 ttctaccata ttctacagct agtttgatag cccttttaca cattaaagcg gaataacatt
     7441 acgtcgccgt cttgtacgac ataatctttt ccttctaatc gaacacgtcc agcttctttt
     7501 gctgcatgca tgtttccgta atgatccaag tcttcaaaag agacagtttc tgcacggata
     7561 aatccgcgtt cgaaatctga atggatgatt cctgctgctt gtggtgcttt gattcctttt
     7621 ttgaatgtcc aagcacgtac ttcttgttcc ccagcagtaa agtaagtagc taagcctaac
     7681 aaatcataag cagcacggat caactgatcc aaacctgatt cttcgattcc taaagcttct
     7741 aaaaattccg ctttgtcttc ttcatctaat tctgcgattt cttcttctgc acgagcactg
     7801 accacgatca cttctgcatt ttcttctgca gcaaagttgc gcacttcttg tacataatga
     7861 ttcgcgtctg catctgctac gtcatcttct gagacattgg ctacataaag aattggtttt
     7921 gtcgtcaata aaaatagtga tttaacgatt ttttgttctt cttcagtaaa ttcgatcgtt
     7981 cgggcagatt ttccttcttc cagtacaggt ttgattttat ccagtacagc tagttctgcc
     8041 actgcatctt tatctttggt tttagcaact tttgctacac gagtatagcg tttgttgata
     8101 gattctaagt ctgctaacac tagttccaag ttgatcgtat caatatcttc tagtggatca
     8161 acacgtcctt ctacgtgagt aatattatca tcatcaaaac agcgaacaac gtgacaaata
     8221 gcgtctactt ggcggatatg gcttaagaat tgatttccca aaccttctcc tttacttgcg
     8281 ccttttacga ttccagcaat atctgtaaat tcaaaagtcg tcggaacagt ttttttcgga
     8341 tgtacaagtt ctgttaagcg ttgcaaacgc cagtcaggta cttctaccat ccctacgttg
     8401 gggtcgatcg tcgcaaaggg atagtttgct gcttctgctc ctgcttttgt gatcgcatta
     8461 aacaaagttg attttcctac gttgggcaac ccaacaattc cagcagtcaa tgccataaat
     8521 ttattcactc tttctctgca tttttttcaa ttactttttt taatttcttt tcaaaatctc
     8581 gacgggtcat catgacgata tgtccgcaat tcatacatct gattttgata tctgcgccca
     8641 ttcgaatgac ttcccagcga ttcgtctggc aagcgtgagg ttttttcatt tcaacgatat
     8701 cgtgcaagtc gtacataaaa atagcctcct ttttgtttat tcttcatcaa attgaatatt
     8761 caagatatca agaattcgag tcaaatcttt ttgagaaaga tattcaatct cgatcttacc
     8821 tttcccattt ttttcttgga tagctacact tgtaccaaat ttatccatca aacgatcttc
     8881 gctttctcgg atataatatg gtttttcctt tgctagcctt gggatttttt tcttttcttt
     8941 tccatcattt tgatttaact cagaaacaag ctgttccagt tggcggacag ttaaattttc
     9001 agttactgca cgattggcta atttcaagat caatgtttta ttttttaaac ctaacagcgt
     9061 acgggcttgt cccatagata aacgctgatc ttgtaccatt tccttgacaa gatccggtaa
     9121 agaaagcaag cgcaaataat tggcgatata aggtctgctc tttcctaaac gactagctac
     9181 ttctgcttgt gttagtttca ggtttttcat cagcatctca tatgcttctg cttcttctaa
     9241 cggattcaga tcttctcgct gcaagttttc cagcactgct acttgcatca tcgcttcttc
     9301 gtcaaagtct ctaacgatag cagggatcgt ttctttttca gctagtttgg acgctcgaaa
     9361 acgtcgctcc cctgcaataa tctcatatcc ttttactgcg gaacggcgta cgatgatggg
     9421 ttgaaagaca cctgattgtt caatagaatt agctagttcc tgcaaagata cttcttcaaa
     9481 tgttttacgg ggctgatacg gatttggtcg cagctcattc aatggtagct ggacaacggt
     9541 atcatctttt acatccaccg tctctaagtt ttctaaatct tgaaacagtg catcgattcc
     9601 tcggcctaat cctttacttt tcttcacgac ttaccacttc ctttgccaat gcttggtaga
     9661 cttcagctcc tcgagaacgt ggatcgtagt cgatgatcgg ttttccatga ctaggtgctt
     9721 ctgataaacg aatatttctt ggaatgatcg tttcgtaaac tttttcgcgg aagtatttac
     9781 gtacttcttc tacgacttca tttcccagat ttgttcgtgc atcatacatt gtcagtaaga
     9841 ctccctcgat ctctaattct ggattaaagt gtttttggac taaacgaacc gtattcagta
     9901 attggcttaa tccttccaat gcgtaatact cacactgaac aggtatcaaa atcgaatcac
     9961 ttgctgtaaa tgaattgatt gtcagatggc caagagaagg cgggcaatcg atcaaaatat
    10021 aatcatactg actgcttact tctgctaaag atccttttaa tcttgattct cttgccatca
    10081 ttgacgtcaa ttcgatctct gctcctgcta attggagagt cgcaggcaca atactcaaat
    10141 tttcgtgttc agtgatcaaa gttgcctcat caattggcaa ttcattgact agaacatcat
    10201 agatgtctct tgtcacatca ggttttctga tcccgacacc actggtagca tttccttgtg
    10261 catccatatc cactagcaat acttttttgc caaggctagc aagacaagca cctagattca
    10321 ccgtcgtcgt tgttttgccg acgccacctt tttggttcgc aacagatatt atttgtgcca
    10381 tctcttctcc tcctatttga ttggctgctt attaggcagt ccgggctttc ttgggtattt
    10441 ctttggggtt ggtttctttt tttgaataac gatgatatgc cgttgatcag agacattcgg
    10501 caaggtaacc gcctcttctt tgaggaattt accacctaat aaagcaatcg cttgttttgc
    10561 ttctgtcaat tcctcttcac tttttgctgc tttcaatgca taaaaatagc cttcttgttt
    10621 agccaagggc aaacacaatt ccgctaacac attcaaacga gcaaccgcac gagcagtgac
    10681 aaggtcaaat gatgcacgaa agtgaggatt ttgcccaaat gtttctgccc ggtcatgata
    10741 taaggaagca tcgattccta ataatcgggt taactcagat aagaaggtta ttcgtttatt
    10801 cagagaatca acgatcgtta tctgcagttc tggaaaggca atttttaaag gtatgctagg
    10861 aaaccctgcc cccgaaccaa catcgcataa agataaaggt tgcgtaaagt ctacttcaaa
    10921 tgctaatgta agtgaatcgt aaaaatgctt cagatatacg tctttttcat ccgtaatagc
    10981 tgtaaggttc atcttttcgt tccattcgac taatgtccga taataaatag cgaattgatt
    11041 catttgatga tcggtaagct ctatcccttt ttctgccaag gattggcgaa attcttctgg
    11101 tatcataaat attcctttca ttgtgaaaca gcaattgttt cacagattct ctccctactt
    11161 taacgcaaaa tctctagaca tgcaatcctt ccatatggat tcttaaaaat ttgaaaagta
    11221 agaaaagccg atagactttt tctttctagt atgactcata aaatatacac agaagagaga
    11281 actagctttg agcaatttct gcaaaaacta gttctctctt ctatttatta ttacgtatta
    11341 cgctggttca ctgactttcg caatcttccc ttgttcgata tagaccatta ggatacttag
    11401 gtctgcaggg tttacgccac tgattcggct agcttgggca attgtttctg gttggatttt
    11461 ctgcaatttt tgttttgctt ctgttgctaa tccgttgatt gctgcgtagt cgatgttttc
    11521 tggaatcttt ttcgcttcca tgcgttttaa tttttctact ttttccatgg cttttttgat
    11581 gtagccttca tatttgattt ggatttctac ttgttcgatt tcttttcgtg tcaattcttc
    11641 attttctgga ataaaccgta gaagttctgc ataagtaatc tcaggacgtc ttaaaaagtc
    11701 gcttgctagt acaccatctt ttaatggtgc cgcattaatc gttgctaaaa agtcttggac
    11761 ttcttctgtt ggtttgattc gtacattcat caaacgtttg atttcttgtt caactgcttc
    11821 ttttttcttc aaataattct tgtattgatc ttcttttact aagcctacac ggtgacccat
    11881 ttctgttaat cgcaaatctg cattatcatg acgtaaaagc agacggtatt cagcacgtga
    11941 agtcagcaaa cgataaggtt cgttcgttcc ttttgttacc aaatcatcga tcatgacacc
    12001 gatgtaaccg tcacttcgtt tgatcactaa aggttctttt ccctgaactt tcaaagctgc
    12061 attgataccg gcaatcagcc cttgtccagc cgcttcttca taaccgcttg taccatttgt
    12121 ttgtccagct gtataaagat tttcaacgac tttagtttct aatgtcggac ggagctggtg
    12181 tggctctact acgtcatatt cgatagcata tcctgtacgc atcatttcta ctttttctaa
    12241 tccagcaata gaatgaagca tgttgacttg aacatcctct ggtaaagaag tagataaacc
    12301 ttgaacatag acttcttccg tatttaagcc ttctggttcc aaaaataatt gatgacgtgg
    12361 tttgtctgca aaacgcacga tcttatcttc gatggatgga caatagcgag cgcctacccc
    12421 ttcaacgatc cctgtaaaca ttggggcacg atgtaagttg tctcgaataa tttggtgagt
    12481 cgtctcacct gtataggtca gccagcaaga ttcctgatct agtttatagg cactatctgg
    12541 tgtgctgaag ctaaaatgat tcggctcttt gtcaccaggc tgctcttctg taacagaata
    12601 gtcgatcgta cttgatttta ctcgaggcgg tgttcctgtt ttgaaccgtt cgatagcaaa
    12661 gccaagttct tttagatgat tcgctagtcc aatagaaggt tgagagttat tcggacctga
    12721 tgaatatttc aattcaccga taatgatttc tccgcgaagt gctgttccgg ctgtaataac
    12781 aactgctttg gcccggtagc tcgctcctgt ggacgtcact actccatgac aaacaccatc
    12841 ttcgacgatc agttcttcga cgattccttg tcttagcgtc aaatttggtt ctttttcgat
    12901 cgtatgtttc atttctgttg aataagcatg tttgtctgct tgtgctcgca atgctcggac
    12961 agctgggcct tttcctgtgt tcaacatacg catttggata taggttttat cgatattctt
    13021 acccatttct ccgcctaacg catcgatttc tcgaacgaca acgcctttag ctggtccgcc
    13081 tacagaagga ttacatggca tgaatgctac catgtccaaa tttattgtca gtaataatgt
    13141 ttttgatccc atacgtgcag cagcaagtgc agcttctgaa ccggcgtgtc ctgcgccaac
    13201 aacgatcacg tcatacgcat ctgcttcata atgttccaat cgtttgttcc tccttttatt
    13261 ttcctaaaca aaattgactg aataattgag tgattagctc atcttgtaca ctgtcgccga
    13321 caacttctcc tagatagtcc cagcaacgcg tcatatctat ttgaacgaga tccacaggca
    13381 ttcctgaatc aatacctgca atgacttctt caagtgagag ggaagctttt tctaacaacg
    13441 cgatatggcg ggtattagaa acataagtag cgtctctttc tcctgtttct ccgctgaaga
    13501 ataaatcaga aatagctgat tccaaacgat ctagtccgtc gtttttagct acggaaattg
    13561 aaaaaactgg ttcattttcg atcaatttct tcaatttttc ttgttccagc tgtgctggca
    13621 aatctgtttt atttagaaga atgatccgtt tcaatccact tgtcgcttcc aataattgtt
    13681 catcttctgc tgtcagtggt tcgctttggt ttagaacaag taagatcaag tctgcttctg
    13741 ctaatgcttt tcggcttctt tcgaccccga tccgttccac cacatcttct gtttcccgaa
    13801 ttccagctgt atcgattagc ttgagcggta ccccccgaac attgacatac tcttcgatta
    13861 catctcgagt cgttcctgca atatccgtaa cgattgcttt ttcttctctt aacaaatggt
    13921 ttaacaaact tgatttgccg acatttggcc ggccgatgat tgccgtactt aacccttccc
    13981 gcagaacctt cccttgcttg gatgtagcaa gtagcgcttg gattctttgt tggatcatct
    14041 gcgctttttc aagcaataac ttcgtagtca attcttcgac atcatcatat tctggataat
    14101 caatatttac ttctacttgt gctaatgtct ctaaaatctc ttgtctcaat gagcggatca
    14161 aagcagacag attgccgtct aactgattaa gagctagtcc cattgctttg tctgtttttg
    14221 cccgaatcaa atccatcaca gcttctgcct gtgaaaggtc aacacgacca ttcaagaatg
    14281 ctcgttttgt gaattcgcct ggctcagcta atcttgcacc ttctcttaac aatagctgca
    14341 aaatttgatt gactacaacg atcccaccgt gacaattgat ttctactaca tcttcccgcg
    14401 taaatgtctt tggtgctctc atcacggaga ccatgacttc atcgacaagc tgattgctct
    14461 tgggatcaac gatatgtcca taatggatcg tatgacttgg tacttctgat aatcgtttgt
    14521 ttccagattg ataaacttta tctgctagtt gcacagcttg atcgccactt aaacgaacga
    14581 tactgattgc accttctcca ggtggggtag aaattgccgc aatcgtatca aattctaaag
    14641 taatttcagc cattttttca cttccttttt cattttgcgc acaaaaaaag tgcccactcc
    14701 accctttatg cacaataaac ggtgaacttc gcactttgac tgcttgttct tgattaaatt
    14761 ctggtcatag attatcacac ttgctataag gaatcaagtg tttaaaacaa ttagatgaag
    14821 ttgagcctgt tctgcttcca ttaccttata tttaattgtc cttggatgtc tctttgcgtt
    14881 ctttggttta ttcgaagaga agatactgta taaacaaggc tttatctttc ttaaaaaaaa
    14941 cggtacacta aatggtagcg ctatctaaac tatacacttt tgaaaggaga aaatatgtga
    15001 gcccgttcag atctgctgca ttggaagaag aaagtgaccc tcggatcaac gatgtcgttt
    15061 tatctacagg gaatatcaac cagaaatata tcgtccgcga tatcgttttt gttgtggaat
    15121 gcttagaagc tgatttgttt gacccatctt ttcccaaaga tgaccttttc ttaacaacga
    15181 agaggaaatt aaagacgaag gtacttgaat atggtgcgaa tgcagtaatc aactgtcatt
    15241 ttgagtatca gcaaaaaaaa cgcgacggaa agtattttct ggaacttttt gcttatggaa
    15301 cagtgatcca atttatccaa acaacgattg gttaaatgaa acagacaaaa aaagcggatc
    15361 aaaactgaag acagtttcga tccgcttttt tctatcaaag ttagtgacta cttcatcgta
    15421 tactctgata agaatgattt ctagtaaaat atacttggtt tgaaaaactt tgtcaacgtg
    15481 atttattcaa aaagtaatgg aatcaataat attttttagc aggttctact actaaataac
    15541 gataaggttc ctcaccttcc gaatgtgttt ttacatgttc atctttgctt aatgcagcat
    15601 ggatttgttt acgttcaaat gcaggcattg gttctaagaa aacaggctgc cctgtccgtt
    15661 ttactttttc agccgtgcga tcagctaaac gctgaatgat ctcttggcgc ttttcacggt
    15721 aattgcctac attgactact acagacagct tatttcttgc taaacgatgg atgaagactt
    15781 gtgccagata ttgcaatgca ttcagtgttt ttccatgttt cccaatcagt atgccttgct
    15841 tttgtgtttc taaatggaaa acaaccatat tatttgattc tctttccatt ttgacaagag
    15901 ctggagcatc aagctgtttt gaaatttcag taagataaac tgccaattcc gttaaagctg
    15961 cttcatcacc tagctcactt acttcttctg ttttttcttc aagaatcgtt tcgttgacta
    16021 cctcgatctc agctgttggt tcttcttcca aaatttcttc tacagtctgt tctactgttt
    16081 cagaaacttt ttcgctgata cttggctgga tcgaaagccg tgcattcttt cgacccattc
    16141 ctaggaaacc tttttttcct tcttccagta tttcgatttc gacttggtct ttggccaaac
    16201 ccaaatcagc cagacctagt tggacagctt cgtctattgt tgcagcttca taaatcggca
    16261 ttagcattac ctcccctatt atttccgttt tttcttagga ttcattgctt tcttaagagc
    16321 acgttctctt tcgcggattc tccgtgcttc ttcttcacgc tcttttcgaa ttttgaaagg
    16381 gttgttgatc agcagcgttt gtacaacttg gaaggcattg gaaactaccc agtataatga
    16441 aagaccgctg gctaaattga cacccatcac taaaatcatt acaggcatca cgaaattcat
    16501 gatcttcatt gatgcattcg attcaatttg actcatgcta gataaatacg tacttgcaaa
    16561 agtaaagatt gctgctaaaa tcggcaaaat aaatgttgga tccgcgttcc ctaagttcaa
    16621 ccataagaaa tgcccttgtt tcaactctgg tacacgtgaa atagattgcc ataacgccat
    16681 caagattggc atttgtacta ataaaggaag acaaccagca tatggattga cgccattttc
    16741 tgcatataaa cgctgctgct cttctcttaa cttactttgt gtttccggat ctcttgaact
    16801 atattgttgc tgcagtgctt ttaatttcgg ttgtaattct tgcgttttac gcatgctctt
    16861 tgtttggaaa tgcatcaacg gcaataggat cacgcggatg atcagtgtaa ataaaatgat
    16921 ccctatccct gcattaccaa atgacaacgc cttgatcgcc tcagcaaagt aataaacaat
    16981 ataacgatcc caaattcctg tactctgtgc gctgacttcc ccagttccgc aaccggataa
    17041 gacgatgacc aaactaacga taccggccat caaaagtaaa cgtttgtatt tcttcactta
    17101 ctcttttcct ctctgtcgat tatttttgca agttttaaga cgtggactaa attggagcga
    17161 acctcatcat aagtcaaccc cttcacactt ggtctagcaa tcacaataaa atccaactcc
    17221 ggatcaattt cttcttttat agaataaact gctgctcgga tttttcgttt gacttcattg
    17281 cggtttaccg cgttgccgac cttttttcct acagataaac caactcgaaa atgaggctgt
    17341 cccggttttt ccaaacggta aacgacgaat ttgcggttag caaaagaatc tcccgtatgg
    17401 aacacggctt gaaactctcg ttcttttttt actcgatacg cttttctcat tagttttctt
    17461 tccttttcta tctctcactt acgctcataa tcataccata attacgattg tcctttcatc
    17521 atttccctaa aaaagagtat aaaaaaaacc actgaaaccc cagtggccta agctgaaaga
    17581 acttttcttc ctttgcgacg acggctagct aacacacgac gtccattttt agtactcata
    17641 cgtttacgga atccgtgaac tttttgacgt ttacgtttat ttggttggta tgttcttttc
    17701 atatattcca cctccaaaat gttcttatct attttataaa cacagacata ctttgatagt
    17761 ataacgacaa agtagtgatt ttgtcaatat aaaatagaag atcgattgtt aaaacttatc
    17821 cacaagatta tttttttcta tgggagtcct atgtggaaaa agttatgcac agggattatc
    17881 cacagataat aaatggctgg ttttacacag aaaacacacg tgtaaaaaaa gtaatccaca
    17941 atcaggtgat ttcctgtgta ttccgtctcc taactattgg tatatctata ttttttatcc
    18001 acagatgcaa gaggaaatct attgattttt acgagttttc cacctgtgca ttagtggtgt
    18061 ggaaaacttt tttttgacaa ctgtgttttt ctcttttttc tttttgtcga ttgtgtggat
    18121 aattgtaatt aaaaaatttt tttcttcggt ttctgtggaa aactattgaa aaaaatgcta
    18181 aattagtact agttattcac tttttaatga aggaggaggc cttatatggt atccctcgat
    18241 gctttatgga atgaattaaa agcaacatac caaaaggatt tatcgcctgc tagctataat
    18301 acatggatcg aaacagcgaa ccctcgaacc cttgatcaaa accagctcgt tgttgaggtt
    18361 cctagcaaga ttcataaaga atattgggaa aaaaacctgg cgacaaaaat cgttgaagtc
    18421 ggttatatgt tatcaggaaa tgagattatc cctcgcttta ttactggcga agaagcagag
    18481 caagaagaag ttatagaaga aaaaaatcca aaagttgtgg cacctagtcc gctaaaaaaa
    18541 gccatgctga accctaaata tacctttgat acgtttgtca ttggtaaagg aaaccagatg
    18601 gctcatgcag cagcgctcgt tgtagcagaa gatccaggtt ctatttataa cccgctcttc
    18661 ttttatggag gcgtgggact tggtaagact cacttgatgc atgcaattgg tcatcaaatg
    18721 ctgcaaagtc agcctaatgc caaagtaaaa tatgtaagca gtgaaacttt tgctaatgat
    18781 ttcatcaatt cgatccaaaa caaaacagca gaagagttcc gtcaagaata tcgaaatgtt
    18841 gatttactgc tagtggatga cattcaattt tttgcagaaa aagaagctac gcaagaagag
    18901 tttttccata ctttcaatgc cttgtacaat gaagggaaac aaatcgtact aaccagtgat
    18961 cggttgccaa acgagattcc gaaactgcaa gaacgcctcg tttctcgctt tgcatggggg
    19021 ctgtctgttg atattacacc gccggatctt gaaacaagaa cagcgatttt acgtaaaaaa
    19081 gcggcggctg aacgtctaga gatcccagat gacacactaa gctacatcgc aggacaaatt
    19141 gattctaaca ttcgtgaatt agaaggtgcg cttgttcgag tgcaagcttt tgctgcgatg
    19201 aatagtgaag atatttcgac tagtctagct gcagacgcac tgaaaacgtt aaaatcagga
    19261 aaaggacatc ctcaattgtc aatcctgcag atccaagaag aagtggcaaa gtattatcac
    19321 atccaattga aagatatcaa aggaaagaaa cgcgtcaaat ctattgttgt tcctagacaa
    19381 atcgctatgt atttggcacg tgagctcaca gataattctt taccgaaaat cggagctgaa
    19441 ttcggtggca aggatcatac aacggttatc catgctcatg aaaaaatcca gcagctgatg
    19501 gattctagtg tcagtatgca aaatgaagta tcagaaatca aaaacttttt actaaattaa
    19561 tttgtcgatt ctatcaactg aaaatagcat gtggataaaa gaaaaaaacg ttcaaaagtt
    19621 atgcacactt tttccacagc tgttttttcg tttctctctt acgttttttg agttttccac
    19681 agaatcaaca tgccctatta cttttattat tctttttaac taataataaa taaacaaaca
    19741 ttcaaaggag atacatcatg aaagttactt taaaccgagc tagctttatg caggaattgc
    19801 aaactgttca acgagctatt tcaagcaaaa ccacgatccc tattttgaca ggtgtaaaaa
    19861 tcacactgac acaagaaggt ttgactttga cggggagcaa cgctgatata tcaattgaaa
    19921 cttttttgtc tgttgaaaac gaaaaagcaa atatgcaaat cgaatctact ggttccattg
    19981 ttttacaagc acgtttcttt agcgaaatca ttcggagact tcctgaagaa acatttactt
    20041 tagaagtttt agaaaataaa caagtagcga ttacttctgg aaaagcgaat tttatcgtaa
    20101 atggattaga tgcagataac tatcctcatc ttcctgttgt cgaaagccat aaccagatga
    20161 aattacctgt acacgtattg actaaactaa tcaacgaaac agtttttgct gtctcacaac
    20221 atgagagtcg tccaatcttg acaggtgtgc atttcatttt atctgataat tctttattgg
    20281 ctgtagctac tgattctcac cgtctaagtc aacgcgtgat tccagtagaa caagcggctg
    20341 atcattttga tattgttatt cctggaaaaa gtttgatcga attatctcgc tcattaacaa
    20401 atgaagaaga aatcgtcgaa atcagcatta tggaaaacca agtgttgttc aaaacagaaa
    20461 cgatgtattt ctattcccgt ttgctagaag gaaactatcc tgataccaat cgtttgattc
    20521 cttcaagttt taatacagag gttgaatttt ctgttcctag ctttttagcg gcgatcgaac
    20581 gggcttcttt actttctcat gaaggccgta acaacatcgt tcgtttatct attcgtccag
    20641 atgcggttgt tttatacgga aattcgccag aaatcgggaa agtagaagaa agcttgagtt
    20701 atacagcaag cagtggcgat ccattagata tttctttcaa tccggattat atgaaagcag
    20761 cgttgcgtgc atttggagat atgagcatca aagtgaaatt tatctctgct attcgtccat
    20821 ttacattgga accaacggaa gatggcgttc aatttattca gctgattact cctgtacgta
    20881 caaattaaca atgattttca ttgttcttga aaatttaatt gaaaagaaat agaaaaaata
    20941 aaattttaaa cagaaggccc taaaatctct tttaaggctt tctgtttatt tttgtttaaa
    21001 tcaccttttt tagattaaat cgtcttatat ggaaaaatat atggataaat ttgttttatt
    21061 gcgaaaaaaa aggtataata gagtatactt ttaataatga aaatgaggga tgggcattga
    21121 aacaacaagt cattctaaat acggaattca tgacgttggg ccaaatgttg aaagaagtca
    21181 cagttatcgg tagtggcgga caagcaaaat ggtatttggc agaaaacact gtgttagtcg
    21241 atggcgaacc agaaaatcgt cgtggacgca aactttatcc cggcatgatg gttgaagttc
    21301 cagaagtagg aacttttttt atggtaaaaa aaggaaacga cgataatgag gctgaataag
    21361 ctgtatttaa aaaattatcg aaattacgaa gagctgaaca tcgaattttc caagaacctc
    21421 gtcatctttt taggagaaaa tgcgcaagga aaaacgaatc ttttggaaag tatctacgta
    21481 ttagctatga cgcgaagtca tcggacaagt agtgagcagg aattgattgg ctggactgac
    21541 gatcaggcga tgattcaagg agagatcaca aaaggttcat ccactcttcc attagaaatc
    21601 ttattatcta aaaaaggccg aaaaaccaag atcaaccata tcgaacaaaa aaagttaagt
    21661 acttacgtgg gacaaatgaa tgtcatttta tttgcaccag aagatctttc tttagtaaaa
    21721 ggcagcccgc agatcaggcg gaagttttta gatatggaat taggccagat caatccaatc
    21781 tatctttatg atcttgtcca ataccaagca attttgaaac aaagaaacca gtatttaaag
    21841 caattgaatg aaaaaaaaca aactgatttg ctttatttgg atattttgtc cgaacaacta
    21901 gcagcgtttg gcagcaaagt attgaaagca agagcacagt tcgtcaagcg attggagttt
    21961 tgggctaatt ctttgcatca gcaaatcacc catcaaaaag agcagctgga aatcgagtat
    22021 ctcaccgcag tcgattcttt agaaacacat acgcaagagc aaatccaaga acaatttctc
    22081 gcacttttga accaaaataa aaagaaagac ctttttcggg gaacaacgac agttggtcct
    22141 catcgtgacg atctttcctt ttttattaat cagaaaaatg tgcagactta tggatcgcaa
    22201 ggacagcaaa gaacaactgc actaagtgtc aaattagcag aaatcgattt gattaaagaa
    22261 gagacggggg aatatccaat ccttttgtta gatgatgtga tgagcgagct ggatgatagt
    22321 cgtcaactcc atctgctaga aacaatcgaa ggaaaagttc aaacgttctt aacaacaacg
    22381 acacttgacc atgtaaaaaa taaaatgact gttgaacctg agatttttta tgttcaacaa
    22441 gggaaactaa aaggagaaga aactgaatga cagaagaaag aagtttagta gaacgcgcta
    22501 aagagtatga tgccagtcag attcaagtac ttgaaggact tgaagccgtt cgtaaacgac
    22561 ctggcatgta tatcggttcg actagttctg agggtctgca tcaccttgtt tgggaaattg
    22621 tcgataattc gatcgatgaa gtattagcag gttttgcaac gaaaatccat gtgattattg
    22681 aaaaagacaa cagtatcacc gttattgacg acggtcgggg gatacctgta gatatccagg
    22741 caaaaactgg acgtcctgca gttgaaacgg tctttactgt tttacatgct ggaggaaaat
    22801 tcggcggtgg tgggtacaaa gtttctggtg gacttcacgg agtaggatct tctgttgtta
    22861 acgcgctttc tacacagctt gatgtcaaag tatacaaaga aggaaatgtg tactatcaag
    22921 aatatcgtcg tggagctgta gtggacgact taaagattat cgaacaaacg gatcgccatg
    22981 gaacaacggt tcactttacg ccagaccctg aaatttttac agagacaact gagtttgatt
    23041 tttcaaaatt ggctacccgg atccgtgaac ttgctttctt gaaccgcggg atgcgtatat
    23101 cgattgaaga caaacgagaa gaagaaccag tcatcaatga ataccattat gacggcggga
    23161 ttaaaagtta tgtcgaatac ttgaatgcaa acaaaaccgt gatttttcca gaacctgtat
    23221 atttggaagg tgaacagcaa gatatcgcag ttgaagtctc tatgcaatat acagacggct
    23281 accattccaa tatcatgagt tttgccaaca atatccatac gtatgaaggc ggaacacatg
    23341 aatcaggatt caagactgct ttaactcgtg tgataaatga ttatgcccga aaacaaaagc
    23401 tgatgaaaga aaatgacgac aacttgaccg gtgaagacgt gcgagaagga ttgacagctg
    23461 ttatttctat caagcatcct gaccctcaat tcgaaggaca aacaaaaaca aaattgggca
    23521 attccgaagt acggacagtc actgatcggt tatttagcga acatttcatg aaattcttgc
    23581 tggaaaaccc aagtgtgggc cgtcaaattg ttgaaaaagg attactagct tccagagctc
    23641 gtctagcagc gaaacgtgcg cgtgaagtaa cgagacgtaa aggtgcttta gagattagta
    23701 atctgccagg aaaattagcg gactgctcta gcaacgatcc tgaaaaatgc gaattgttca
    23761 tcgtcgaagg agattcggcc ggcggatcag ctaagcaagg tcgtaatcga gagtttcaag
    23821 ccatcttgcc tattcgtggg aaaatcttga atgttgaaaa agcaagcatg gacaagatct
    23881 tggcaaatga agagatccgg tctttattta ctgctatggg tacagggttt ggagaagatt
    23941 ttgatgtatc gaaagctcgc taccacaaat tagttatcat gactgatgcc gatgtcgacg
    24001 gcgcgcatat ccgtacattg ctgctgactc ttttttatcg ttacatgcgt cctattgttg
    24061 aagctggata cgtctatatt gctcagccac ctttatacgg ggtaaaacaa gggaagaata
    24121 ttacgtatgt acaaccagga aaaaatgcag aagaagagtt gaaacaagtc gttgcttcac
    24181 ttcctgcctc accaaaacca agcgttcagc gttataaagg acttggagaa atggatgatc
    24241 atcaactatg ggaaacaact atggacccaa gcaatcggat gatggcccgc gtcagtgtgg
    24301 acgatgctat tgcagcagat cagatatttg aaatgttgat gggggatcga gtagaacccc
    24361 gtcgtgcatt catcgaggaa aatgcacact atgtgaagaa cttagatatt taatcatgaa
    24421 ggaggaaaaa gaatgagtga agaaatcaga gaaaacatcc atgatgtcaa tctaaccagc
    24481 gaaatgaaag actccttcat cgattatgcg atgagtgtta ttgtcgcacg tgcacttcct
    24541 gatgtcagag atggtctgaa acccgttcat cgccgtattt tatacggcat gaacgaatta
    24601 ggtgtaacac cggataaagc ccataaaaaa tctgccagaa tcgtcggaga tgtcatgggt
    24661 aaataccatc ctcatggaga ctatgcgatc tatgagtcaa tggtacggat ggcacagcca
    24721 ttcagctacc gttatatgct agtggatggt catggaaact ttggttctgt tgacggtgac
    24781 ggtgccgccg ctatgcgtta taccgaagca cggatgagca aaatcgctac agaaatgctg
    24841 cgtgatatca ataagaacac tgttgatttc caaagcaact atgatgatac agaaaaagaa
    24901 ccagttgtac tacctgctcg cttcccgaat cttttagtga acggaacaac ggggatcgcc
    24961 gtaggtatgg ccacgaatat cccacctcat aacttgtctg aggtagtagc ggctatcgat
    25021 ttgctgatgg ataatcctga tgtgacgacc aatgaattga tggaagtatt acctggacca
    25081 gattttccaa caggtggttt ggttatggga aaatcaggaa tccgaagagc gtatgaaaca
    25141 ggtaagggtt ctattaccgt acgtgcaaaa gttgagatta ctgagatgcc aaatggtaaa
    25201 gaacggatca tcgtgacaga attgccttat atggtcaata aagcaaaatt gatcgaacgg
    25261 atttctgaac tgcacagaga caagcgtatc gaagggatca cagatttgcg ggacgaatct
    25321 tcccgtgaag gtatgcggat cgtcattgac atccgtcgtg acgccagcgc atctgttatc
    25381 ttgaataact tatataaatt gacatccttg caaaattcat ttggattcaa tatgttggcg
    25441 atcgaaaaag gtgtgccgaa agttttgagc ttgaaacaaa ttcttgaaaa ctatatcgaa
    25501 catcagcgcg aagtcatcac aagacggaca gtctttgaaa aagaaaaagc agaagcaagg
    25561 gcacacattt tagaaggttt gcgtattgct ttggatcata tcgatgaaat cattgcgatt
    25621 atccgcgggt ctaaatcaga tgacgaagca aaagcgacga tgatcgaacg gttcgattta
    25681 tccgatcgcc agtctcaagc tattttagat atgcgtttac gccgattgac cggtttggaa
    25741 cgggaaaaaa tcgaaaatga ataccaagaa ctcttaaaac tgattgaaga tttaactgac
    25801 attctggcaa gaccagaacg tgttacagaa atcatcaaga atgaattagc agacttgaat
    25861 caacgatttg gtgataaacg acgcacagaa ttactagtcg gtgaggtctt aagtctggaa
    25921 gatgaagatt taatcgaaga agaagaaatc gttattacat tgacaaacaa tggttacatc
    25981 aaacgtttgg caaataatga attcagagct caacgaaggg gtggacgtgg tgtccaagga
    26041 atgggtatcc acaatgacga cttcgtcaaa aatctggttt cttgttctac ccatgataca
    26101 ttgttattct ttacgaataa cggaaaagtg tatcgggcaa aaggatacga aattccagaa
    26161 tacgggcgca cagccaaagg aataccaatt atcaatttac taggtatcga ttcgagtgaa
    26221 agcatccagg caatcattgc ggtgacggga gaagcagaag aaggccacta tctcttcttt
    26281 acgacgcgtc aaggtacagt aaaacgtact tctgtcactg cttttgctaa catccgaagt
    26341 aatggtctga tcgcaattgg tttgaaagaa gacgatgagc tcgtcaatgt gctactgaca
    26401 gatggtcaat ctaatatcat tattggaaca cataacggct actctgtcac tttcaaagaa
    26461 gaagcagtcc gcgatatggg acgtacagct tccggggtta gaggaatacg cctgcgtgag
    26521 gaagattatg tcgttggggc agccttaatg aaggaagatc aagaagtatt agtgatcaca
    26581 gaaaaaggtt acggaaaacg gacaaaagta tcggaatatc cagtgaaagg ccgcggaggt
    26641 aaagggatca aaacggcgaa catcactgaa aaaaatggtc cactagctgg attgaccact
    26701 gtttctggag atgaagacat catgctgatt acagataaag gtgtcattat ccgtttcaac
    26761 gtatcgactg tttctcaaac tggacgttca acattaggcg tacgtttgat gaagatggaa
    26821 gctgatacga aagttgtcac gatggcagca gtcgaaccag aagctgcaga acaaacagtt
    26881 gaagaacaag gatcagaaga atagccatca agactaattg tgtaagctag caagaatgac
    26941 cgattaaaaa atctggttat tcctgctggc ttttttgatt agttgaattt ctcttaaaat
    27001 attcgaaact gttcattctg tattgctttt gaccaaaata gagtgtataa tcagagcttg
    27061 tgagtagtct aattaattag ataactctcc ttgctcttag gaacctaaga gccgaaagtc
    27121 cacagggagg tgaatatcaa tggaaaacac gaaatatgaa atcatgtaca ttattcgtcc
    27181 aaacattgat gaagaagcaa aaactgcttt aatcgaacgt ttcgatgcaa tcttgaaaga
    27241 taacggagca gaagttatcg aatcaaaaga ttgggaaaaa cgccgtttcg cttatgaaat
    27301 gaacggttac cgtgaaggta tctatcacat cgttaaagta tcttctccat catcagcaaa
    27361 tgctgtcaat gaatttgacc gtcttgctaa aatcaacgac gatatcattc gtcacatgat
    27421 tgttaaagaa gaagcttaat tgttgtttca tgtgaaacaa tagaaaacga tgagaggaga
    27481 tgactatttt gattaataat gttgtattag ttggacgtct gacgaaagat ccagatttgc
    27541 gttacacagc aagtggtacg gcagtcgcaa catttacttt ggctgtgaat cgtaatttta
    27601 caaaccaaag cggcaatcgc gaggctgatt ttatcaactg tgtgatttgg cgcaaatcag
    27661 cagaaacttt agcaaactat gctcgtaaag gaacactttt aggtgttact ggacgtatcc
    27721 aaactcgttc ttatgataat cagcaaggac aacgtgtata cgtgacagaa gtagtagctg
    27781 acaacttcca attgctggaa agtcgttctg catctgaaaa tcgccaacaa agcggcggat
    27841 tccaaagttc tggtcaatca gctggcggat ttggcggaaa caataactct aatcaaacat
    27901 ctcaatcatc caacggtatg cctgatttcg accgtgatac ttctgaccca ttcggctcaa
    27961 gttcaacgat cgacatttca gacgatgatt taccattcta aacgaatttg ataggaggga
    28021 aatagaatgg cacaacaaag aagaggcgga cgtaaacgtc gtaaagtaga ctacattgct
    28081 gctaaccata ttgaatatat cgattataaa gatatcgaat tactaaaaag atttatttca
    28141 gaacgcggta aaatcttgcc acgtcgtgta actggtacag gcgctaaaaa ccaacgtaaa
    28201 attactgttg caatcaaacg cgctcgtatc atgggcttgc tacctttcgt tagcgaagac
    28261 taataaatcc taggaattga atgactgatc cttttgatca gctattcaat tccttttttt
    28321 ctgtaaaaat aacctctatt cgtttagtcg ctcgaatgac gaaagttatg gtaaaatcaa
    28381 attagtcata tatgggagga aaattatgga aaataaaaac aatcatttat ccccgaaacc
    28441 tctcttcctt atcctgttta tattaatcga agtattggta gtcttaattt taccatttcg
    28501 ttttgttagc gcttcggtca ttctattgat gaatttatgg ggtgttcgct attggttgaa
    28561 aatgaaacgt tggcttattt taaataaacg tgaaaaaatc cagcaggctt cgactgtagc
    28621 tgaaaccaat ctagcttatg tctcagaagt catgcctgta ggagtgattg cttatcagcc
    28681 atcaagccaa aaaatcgaat ggctcaatcc attagcattg aaaatcaaag atcaaagtgg
    28741 attaacagag gaagaattgc tagatacttt ttttactgca aaagaaaaaa agaaaaacca
    28801 agtctatcta gcagataaaa catttcagtt tgatatggat acagtaaagg gtgttgttta
    28861 ttttaatgat attacccaaa accagttgtt aaaactccat cagacgaaca gtcagccggt
    28921 gattggtatt ttatctattg ataactatgc agatgccatt gataaattgg atgacaaaga
    28981 gatttcttat ttgaactctt tcgtcactac actagtttct gactggatga atgaatacca
    29041 tgtctttttc aaaagaatca acgcagaacg gtttttcttc gtagcacaga tgatcgatct
    29101 gaaaaagatg atggataaaa aatttgattt gctggatcgc tttcgagcag aagctgaaaa
    29161 acagagctcg cctatcaccc ttagtatggg gattgcttat ggctcaagaa ccctcgatga
    29221 aatcggtgga gaagctcaga ataatttaga tgttgcttta gtccgtggag gcgaccaagt
    29281 tgtcgtgaaa gaggtaaaag aaggagcaaa acctgtttat tatgggggga aatctgctaa
    29341 gaatgtcaaa cgcacgcgtg ttcgttctcg agcgatgagt accgctttgc gtcggatttt
    29401 tgatgaaaca ggcgatgtgt ttatcatggg gcacaagttt ccggatatgg atgctttagg
    29461 ctctgctttt ggtgtcagtt gtctggcacg cttcaaccag aaaaaagctt acatcgttat
    29521 caacgagaac gagatcattc cagatgtaga acggtgtctt gaagaaatcc ataagcatcc
    29581 tgaattagaa atgcaactaa tctctccaga acgtgccata gagctgaaaa aagaagagga
    29641 cctcctcgtg atggtggatt accataaacc ttctctatcg atctctcagg gcctatatga
    29701 gcaatttgat aagattgtga tcattgatca ccatcgtcgt ggggaagagt ttccaagtaa
    29761 acctctgctg acttatatcg aatcttcagc ttcttcagct tcagagctag tttctgagct
    29821 gatccaatac caaagcagca aaacaaatcg cttagatcgt tttgaggcca cattattgct
    29881 tgcagggatg gttgtagata caaatagttt caatgtccgt acaactgcac gaacttttga
    29941 cgttgccagc tatttaaggt cttgtggagc agacgcatcc ttagtacaat atttattgag
    30001 ctcggattta gcgacatact tggagatcag caatttgatt gctggaagcg actatgtgac
    30061 ttctgatatt gttgtggcgg cagggacaga cgaaaaagag tataatagtg ttatagcagc
    30121 aaaaacagca gatacattgc tttcgatgat caatatcaat gcagctttcg tcattacaaa
    30181 gcggacagac ggcttgattg ggatcagtgc cagaagtacc ggcacgatca acgtccaaat
    30241 catcatggaa tccttaggtg gcggaggaca cttcacaaac gcagctactc aactggaaaa
    30301 tacgacagtt gaggaaacaa aacagaagct atttgctgca atcaaagaaa atatgaatca
    30361 aatatatgat aaggagtaat ccaaatgaaa gtaatttttt tacaagatgt aaaaggaaaa
    30421 ggtaaaaaag gggacatcaa agaagttcca gcaggttatg cacaaaatta tctaatcaaa
    30481 aataacttgg caaaagaagc aacgaaaagc agtatcagtc agttagcagg acaaaagaaa
    30541 gcacaagaaa aacacgaagc tgaaatcttg gaagaagcta aaaagttaaa agaattcttg
    30601 gaaaaagaag atactgtagt cgaattgaag gcgaaagcag gggaagacag ccgtttgttt
    30661 ggttcgatcc cttcaaaaca aattgctgaa gggttaaaca aacaatacaa aatcaaatta
    30721 gataaacgaa aaatcgaatt agaaaatccg atccgttcac taggctacac aaacgtacct
    30781 gttaagcttc atcatgaggt gacggctacg atcaaagttc atgtcgtaca agaataacaa
    30841 atcttgatag cgatgttcag ctggtaagta taaccagaag gaaaaaagac aaaccgaaat
    30901 ttatctgaga aaacagctgc agcaatgaaa gcaaaagctg caaatcgatt tcagattgat
    30961 ttcggtttct tttttgggaa cagcaaaata gcataaagaa aacgagtata ataaaagaga
    31021 actatttttt tattacactt tcggtacgaa tgatgacttt tctctcattt tcttgtaaaa
    31081 tgaagcaatt gaagacaagg agcgatacgt atgaatgaag tgtggcagga tcgaatccca
    31141 ccgcaaaata ttgaagctga acaagcggtt ttaggctctg tttttcttga cgcagaaacg
    31201 atcattgatg ccatggagta catagagcca aaagactttt atcgtcgtgg ccatcaaatt
    31261 atttttgaga caatgatcga gttaaatgat cgtaatgaag cgattgacgt ggttactgtc
    31321 aaagaccggc tggaacaagc caatttgtta gaagatgccg gtggtttaag ttatctctca
    31381 gacttggcat tagcagttcc gacagcagca aatatcgtct actatgcgaa aatcgttgaa
    31441 gaaaaatcat tgctgcgtac attgatccag acagcaacag gaatcgttac gaaaggattc
    31501 gagcaaggag aagaagttca aacaatttta gatgatgccg aacgcagtat cttggaggtt
    31561 tcggaaaaaa gaaatcgaag cggcttttta tctattgctg aagtactgaa ctccacgatt
    31621 gaaaatatcg atcgactagc tcaaaacaat gaagaaatca caggtctacc aactggctat
    31681 caaggtctgg ataaaatgac agcaggtttc cagcccgaag aactaatcat tcttgctgca
    31741 cgtccagcgg taggtaaaac agcgtttgca ttgaatattg ctcaaaatgt aggaacaaaa
    31801 acagatcgtt ctgttgcgat atttagtttg gaaatggggg cagaatctct tgtaaatcgg
    31861 atgctttgtg cagaaggttc gattgaggcc agccatttac gtacaggtca gctttcggaa
    31921 gaagaatggt cgaatctgat cgttgcgatg gggagtcttt ctcgagcaaa tatttttatc
    31981 gatgatacac cagggatcaa aatctctgaa atccgtgcga aatgtcggaa actagcgcaa
    32041 gaaaaaggca atctaggctt gatattgatc gattatttgc agttgattga aggtaacggt
    32101 aaagagaacc gtcaacaaga agtatcagat atctctcgcc aactgaaaaa actggcgaaa
    32161 gagctgaaag tacctgtcat tgctctttca cagttatctc gtggagtaga acagcgacaa
    32221 gacaaacgac cagtgctaag tgatattcgt gaatccggat caattgaaca agatgcggac
    32281 atcgtagcct tcttgtatcg agatgattat tatgaaagag aaggcggaga tgacgatgat
    32341 ggaaacgagc caaaaaatga caacgtcatc gaagtcatca tcgagaagaa ccgaagcggt
    32401 gcacgaggaa cagttgaact actgtttatc aaagaataca ataagttttc gtcgctttcg
    32461 ccaagagaag aattttaaag aagaggttgt gagccttgag caatcccgag agctctcgta
    32521 agaagatgca aggagtaacc gcaggaacga ctagagtact taatttaaac agatctccaa
    32581 agggattgtg acaaaagtct tgtcacagtc cctttttccg aataaacggt gttcaatcag
    32641 ctgacccttg gtattagctc agcaaacgtc aaaatatgag gaactatttt gacgtttgtt
    32701 tctctaatac tcaggtcaaa acgctgatct tacgacctct tttccttaaa cggtgttctc
    32761 ctgccaactc ctcggtcaca agtcacaata tcatcaaaca tgagaagcag ttttttgaaa
    32821 ttgctccttg tgactcagag ttaaacggca ggctcacaac ctctttctta aacggtgttc
    32881 aaaagcttgc atctgcggta atacgcccaa tcaaacgaaa aatatgagaa gctatttttg
    32941 tttggctgtt cttattactt gatgcaggac agctttttca caacctctga ttcacggtgt
    33001 tccaaaagta gcttcttcga aaaataagtc gaaatttcac aaaaatttga gaagcaattt
    33061 tcgtacattc cttcttattt cttgaagctg accacttctg ttacaacctc ttttttaata
    33121 accattctaa aaagataaag ttcgtttttt aagcgttttt ataaaataaa aataaaaatc
    33181 attcgatttt atttgaaata tgtatctatt attgatacaa tggttcagga ttaaataata
    33241 tagaacgagg tgttcacatg tcatctgtag tagtagtagg tacgcaatgg ggcgatgaag
    33301 ggaaaggaaa aatcacagac tttctcagtg aaaatgctga agtgattgca cggtaccaag
    33361 gtggcgacaa tgcagggcac acaattaagt ttaacggtgt gacttataaa ctgcatttga
    33421 ttccttctgg gattttttat aaagacaaga tcagtgtgat cggaaacggc gttgtagtca
    33481 atcctaaatc attggttaaa gaattagctt atttacatga aaaaggtgta gaaacaagta
    33541 atttgcgtat ttctgaccgc gcgcacgtaa tcttgcctta tcatatcaaa ttggaccaat
    33601 tacaagaaga tgctaagggc gaaaataaga ttggtacaac gattaaagga atcggacctg
    33661 cctatatgga taaagcagct cgtgtaggta tccgtattgc agacttatta gataaagaaa
    33721 tttttgaaga acgtcttcgt ttgaatctag atgacaaaaa ccgtcaattt gtaaaaatgt
    33781 ttgattcaga accacttgat tttgacgata tttttgaaga atattatgaa tacggacaac
    33841 aaatcaaaca atacgtcaca gatacttccg ttatcttgaa tgatgctttg gatgcaggca
    33901 aacgcgtgtt gtttgaaggc gcacaaggtg taatgctgga tatcgaccag ggaacttatc
    33961 cttttgttac ttcttctaac ccagtagccg gtggggtaac aatcggaagc ggtgtagggc
    34021 cttcaaaaat caataaagtt gtcggcgtct gcaaagccta tacgtcacgt gtcggtgatg
    34081 gaccatttcc aactgaatta tttgatgaaa caggagaaca aatccgcgaa gtaggacgag
    34141 aatacggtac gacaactggt cgtccgcgtc gtgtaggctg gtttgattct gtagttatgc
    34201 gccattctaa acgagtttca ggtattacca acctatcttt aaactcgatc gatgtattaa
    34261 gtggattgga aacagtaaaa atttgtacgg cttatgaatt agatggcgaa ctaatctacc
    34321 actatccagc aagcttgaaa gagttgaacc gctgcaaacc aatctatgaa gaattgccag
    34381 gctggtcaga agacattaca ggatgcaaaa cacttgcaga actgccagaa aacgcacgta
    34441 actatgtacg tcgtatctca gagcttgttg gtgtacgtat ctcaacattt tctgtcggac
    34501 ctgatagaac acaaacaaac atcttagaaa gcgtctgggc gcaaatctaa ggataaaaac
    34561 gacgactgaa tcaggacgtt cttaccagag cgagtcgaag tgtttatcta tacgataata
    34621 ataacttgaa gaggtagtga aagagacgtt tagccttatt gccgataggc tgtctcttga
    34681 acactgttta ttcagaataa gggactgtga caaaaaccgt gtcacagtcc ctttttccga
    34741 acaaacggtg ttcaaaagct tgcatctacg gcactaagcc caatcagatg aaaaatatgg
    34801 agtgctattt ttatctgatt gttcttactg cttgatgcag agcagctttt tcacaacctc
    34861 tccactaaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat tcaacaaaca
    34921 tgagaagctg ttttttgaaa ttgttccttg tgactcggag ctaaacggca ggctcacaac
    34981 ctcttggtaa acggtgttca atcagctgac cctcggtatt agctcaaaaa acggcaaaat
    35041 atgaggaact attttttccg tttttttctc taatactcag gtcaaaacgc tgatttcaca
    35101 acctctgatt cacggtgttc cagaagtagc ttctacggaa ataagccgaa atttcacaaa
    35161 aatttgagaa gcaattttcg taaattcctt cttatttctt gaagctgacc acttctgtca
    35221 caacctctta ttttgattag aacttgcgaa aataaaccgg ttaaagtgtg tctagcgcaa
    35281 gagatttgct ataatagacg ataagggtaa aatgtaacga gaaggggttg aaaaatgtgt
    35341 atcaaattgt aacagattct tgttgtgatc tgccatacca tgtattagca aaagaaaaag
    35401 ttgatttttt atcaatgaat ctccaattga atgatcaaga gttagtagat gacctcggaa
    35461 agacattcaa ttatgaccgc tacatgaatc agctgaaaaa tggtgcgatg cctacgacat
    35521 cacaaatcaa tgttggccga tatttagaat ttttccgttc ttatgcggaa aaacagattc
    35581 ctgttttata tgtggctttt tccagtggat taagcggctc ttacagtagt gcgcttcaag
    35641 cggttgaatt gctgaaggaa gaatatgaag accctgagat ctatgttttt gatacaaaag
    35701 ctgcaagtat tggggaaggg cttttagtat tggaagctgt aagattgaaa aaagaaggta
    35761 aaagcatcga agaaacccta gagtggctgg aaagtaatta tttgaaagtc cattcatggg
    35821 taacagtaga cgatctgaaa tatctagaac gaggcggtag gatttccaaa gcaagtgcta
    35881 ctcttggcag tctattgagt gtaaagccta ttattacggt ggataaagaa ggaaggctga
    35941 cgaatgttga caaagttcga ggaagaaaca agtcgatcca gacaatcgtc aatgagacgg
    36001 taaaaacaat cgttgcacca cttgatcaaa tcgtttatgt ggcttacgct ggggatctag
    36061 agagcgcgga gaaggcaaaa cggcttttgg aagagcagat aaagatgaaa gatgtgaagc
    36121 tttatccctt aggaccaacg atcgccagtc acacaggcta tggctgtatc gcgatttttt
    36181 cgatgggaat cagtcgataa aagcagtaac tcattctgta aaaaagccca gaaattgatt
    36241 gtaacaaaaa cagcgactct taaaagatag atgagcatcc tatctcttag aggtcgctgt
    36301 ttttttattt tttaagctaa ataggccatt atgcccataa ctcgttcaat tgtttttgaa
    36361 tatctgcatt ttccaaaaat tcatcatatg tcgtatcagc tcgatcgatc acacctttat
    36421 ccgaaacggc aatgatgcgg tttgccaatg tttggataaa ttgatggtca tgtgacgcaa
    36481 ataagattga gccagtaaat gccatcaagc cgtcattcaa tgctgtgatt gattctaagt
    36541 ctaaatggtt cgttggatca tctaatacaa gtacgttagc tttcgaaagc atcatttttg
    36601 aaagcatgca acggactttc tctccaccag ataaaacatt cactggtttc aatacttctt
    36661 caccagaaaa caacattctt cctaagaagc ttcttaagaa ggtgttatca tcttcttctt
    36721 tacttgcata ttgacgcaac cagtctaaaa tcgttagatc agtatcgaat tctttcgttg
    36781 tatcctttgg taaataagaa ttacttgttg tcacacccca acgtactgtt ccagtatctg
    36841 gcgtaatttc acccatgata actttgaata gcgttgttgt tgttatatca ttttctgcga
    36901 cgaaagcgac cttgtcttct ttgctcaaat taaaagatat atcatctaaa attttctttc
    36961 catcaatcgt tacacttaca ttttctacct gcaataagtc gtttccaatc tcacgttcag
    37021 gtttgaatcc aacgaatgga taacgtctag aagaaggttg gatatcgtct aaagtaattt
    37081 tttcaagcat ttttttacgt gaagttgctt gttttgattt tgatgcattc gcactaaagc
    37141 gggcaataaa ttcttggagt tctttgattt gttcttcttt tttggcattt gcgtttgctt
    37201 gaagtttagc cgctagttga ctagattcca accaaaaatc ataatttcct acataaagtt
    37261 tgattttacc aaaatctaga tccgccatat gtgtacatac tttgttcaaa aagtgacggt
    37321 catgggatac aacgatcaca gtattttcaa aattgatcaa aaattcttcc agccaattga
    37381 tcgattggat atccagaccg tttgttggtt cgtctagcaa aagaacatca ggtttaccaa
    37441 atagtgtttg tgctaataac acttttacct tttgtccacc agttaattca ctcatttgct
    37501 gatggtgcaa ttcttcaggg atgttcagac cttgcagtaa aacagctgct tctggttcag
    37561 cttcccatcc attaagctca gcaaattctc cttctaattc agctgctcga ataccatctt
    37621 cgtcagtgaa atcctctttc atgtaaatcg catctttttc tttcagcact tcatacagac
    37681 gcttgtgtcc catgatgact gtttcaagta cagtatagtc ttcatagtcg taatggttct
    37741 gtttcaatac ggccatccgt tcatctggtc ccatagtaac ggaacctgtg gaaggctgca
    37801 gatcccctga taacacttta aggaacgttg atttacctgc accatttgca ccaatcaagc
    37861 catagcagtt tccgggggta aatttaatat tcacatcatc aaatagtttg cggtctgaaa
    37921 agtgcaaact cacatcattt acagtaatca atttttttcc tcacttttat cattattagt
    37981 tttgacaagt cttatagaat tatatagggg aaaggtaaaa gattcaaggc aatcgaacat
    38041 tctttgtgtt tcacgtgaaa cagaatgaaa aaaataaaaa taaaagcgga gcgaaaatag
    38101 ctactatagg atttattagt ttgcaacagc ataatttttg acgttattta taagagggag
    38161 tactataaaa ctgtaaaaga aatgaaagaa ggattgaaaa tggatgaaaa aagaaccatc
    38221 gactggggct cattgatttt gggaatttta tttgtacttg tctcattgtt atcatttcaa
    38281 gaccctgtcg gaaatttagt tgcaattgta gtagtctttg cgatttttgc ctttattaaa
    38341 gggatatttg aactgtttgt acggaacaga ttaaaagagc taacaggata taaaggaaag
    38401 atgcccttaa taatcgggat catcgatatt ctagttggcg tctttttctt attcaatatt
    38461 ggtgcaggag tcgcagcatt gccttttgtt tttgcagtat ggtttattgc tgattcagtt
    38521 ttagcgttat ttactgctga cttggcaaga ggagtaagtg aaggatatta ttggtttacg
    38581 atcatcgtca atattttagg aattttatta ggaattttct tattgtttaa tccaatttct
    38641 tctgcgttga cattaagctt tttagttgga ttctatttta tgttatttgg tatcacacat
    38701 atcgtctatg catttagata agtaaaatca aacaaataaa aaagccggct tccgattaca
    38761 gttttactgt tgtaattgga agccggcttt tttatcatgg acaaatatgc acgaggtgat
    38821 ttttaggtgt cgagacaaat ttatgcaaaa atgtgagaag ctatatacac aaattttatc
    38881 ttaatactcg aagcatagcg cagttgtcac aacctctttt catataattc attcaatact
    38941 ggcaaatcat ggacttcata tttttctttg aatgcttgga tttcttcttc agaatatttt
    39001 cttggatcta aatgcagatc ttctactggc aatgggcgct tgttattgat cttcacatcg
    39061 attactacag gacgatctga ttttgcagct gcatcaaagg caaatcgaag ttgcgagtat
    39121 tctgtgactg taaagctatt tgccccgagc gcttctccaa ctttaccgaa atctgcatct
    39181 tctaaaaata caccaaattt cttttgttcc gtatcttctt gttctgcttc gatgaaacca
    39241 aaagaatcat tcgaaaagac aacattaata attggaagct gatatttgac ttgtgtaatg
    39301 atatcttgca tgaccatagc aaacccgcca tcaccactta aggtaaatac ttgtttttct
    39361 gggtagctta gttgtgcggc aattcctcct ggcacaccat tacccatagt tgcgaaccat
    39421 ccagatgtcg tatgtttttg tttaccgttc atattcaata aacgaataga atggatagtc
    39481 gtgttaccga catctgtgac gaaaatcgca tcgtcttcag caatacgatt gatttcttta
    39541 tagacagcct ctggacgaat cggttcttcc tctcgatctt caaaagattt caaccaattt
    39601 acccattttt ctttattttc ttgatttgct aggtaccagc tatcagcagg gcgagcatcc
    39661 cctaactcga caagtctttg caaagctgtg tttgcatcac cgaggatcga caaagatgtt
    39721 tcatggcgtc gtccaaattt tgacgcatcg atatcgattt ggataaattc agcagttgga
    39781 ttaaaaaatg cacgtccaaa tgggaagtcg ctaccgacaa ataagatcag atcggcttct
    39841 gccaatgctt catttccggg tttagtagcg acacgtccag caaaaccaag aaagttttca
    39901 taatcatcag gaataattcc ttttgctaga acggaagcga caacaggaac tgaaaaatgt
    39961 tctgagaatt ctttgatttg cggaaatccg tttcgcgttc cttgaccaac ataaagaact
    40021 ggtttttttg ctttttcaag ataaggcaaa gcagctagca aatctttttc ttctggtaat
    40081 atcacacttg ttttgtgagt gtgagcggtg gagaaaggtt gttcgtcaat ttcttcaaaa
    40141 ccaagatcaa cagggatagt cacgatagcc acgcctttat gctcataggc ggctttaatg
    40201 gcttcatcta ctacatgcgg aagactttgt ggtgtcatga ctgtacgatt gtatacgcta
    40261 acatctgcga aaataggatt ttcatttagt tcctggaaag agttatagtt catggatgta
    40321 gaagcaactt gtcctaagaa cgctactaga ggcacatggt ccatctgtgc atcatacaaa
    40381 ccattgatca aatgtgtcgc accaggtcct gcagagccga agacagcgcc gactttcccc
    40441 gttaattttg catctgcagc ggctgcgagt gcgccgactt cttcatgacg aacttgaatg
    40501 tagttgattt cggttttttc ttgatatagc gcatccataa ttgaattgaa agatcctccg
    40561 ggaatgccgt aaatatggtc gataccccag ctttcaagaa cttttaccat tgcgattcct
    40621 gcattgattt ttgacatggt gtttcactcc tttagcaatg atgatacata aattttttgt
    40681 atctagagta tagaactttt tatcgaaaat cccaactaat tcgtcttttc acaaaaatgt
    40741 agtcatgttt ttgggaatat gctagagtag tacatagata gattcaagag aggggaatgg
    40801 catggttgaa tggctattga gacttgaacc ttggcagcaa gcacttgctg ggacagcttt
    40861 tacttatttt atgacagctc ttggtgccgg gttggttttt ttctttaaag aaatcaaaaa
    40921 agaagtgcta aacttgatgt taggatttgc ttctggtgtc atgattgctg caagtttttg
    40981 gtctttgtta gatccggcta ttacaaaagc agaagaaaat ggagatattg cttggctagt
    41041 tgtaagtatt gggtttggtt taggcggtgt gtttttatat atggcagata aaacactgcc
    41101 ccatatgcat tttggaccac aacatgaagc agaaggattg cctacccatt taaaacggac
    41161 gatcttgctt gttttttcta ttacattgca taacattcct gaaggtttag ccgtgggggt
    41221 agcattcggt gcagcagcaa ctgcggataa tccgacagcc gctatattag ccgctgtttc
    41281 ggtggcgcta ggtattggta tccaaaactt cccagaagga gcagctgtat caatcccgtt
    41341 gcgacaagaa ggtctgagtc gtaaaaaggc ctttgtttac ggacaagctt ctggaatcgt
    41401 tgaaccaatt gctggagtga ttggagcgct actagtaacg aaagtggagc tgctgcttcc
    41461 ttatgcactt gcttttgccg caggagcaat gatttatgtc gtggtggaag aattgatccc
    41521 tgaagcacag cagacattgt ccagcaaaca tcattttgca gtttttggcg tcatgagtgg
    41581 atttatcatt atgatgattt tggatgtggc attaggataa ataaaaaaaa tatatatgat
    41641 atatcaaata gggccgcgaa cttatatcgc gaccctattt ttttagtaag ttatatcata
    41701 atgaagtgaa tggtatcata cattaataat agttttttct atgtgtattt cctttgatcc
    41761 agcgaacaag ccagatgata agtgcgattg ggattagaac tttgaccgca aaccataaaa
    41821 gcccgcttag gacactgaca aaaagactga tgacgaagct agctgcaatt agcactaaaa
    41881 gaaccatgaa gatatttaag aacatatttt tttgacgcat acaaaaccct cctcttgttc
    41941 attctttact atagaaaaag tataacaggg attgtttaaa aacacctcca actgaagact
    42001 gatttttact tcatctactt aaatgatcaa acaattgctt tttctctggt ttatcatcta
    42061 aaatagagcg gaaaaggagg agaatatcat gcctaaaaat cgtcttgaag catttacaga
    42121 tgctgtaatc gcgattatca tgactatttt agttttagaa cttcatgaac ctaacggaga
    42181 cacgtgggag gcgctcgctg cattaggtta ccgatttttt atctatattg tcagttttat
    42241 cattttagcg atttattgga acaatcatca tcatttattt caagttgtac ataagataaa
    42301 tggacgggtc ttatgggcga acagtttctt tgtttttgcg ctttcgcttt ttccgtttgc
    42361 aacttcatgg atcagtgagt acatcaatag cctggctcca gaaatgactt atggttttgt
    42421 taccttgacc gctaatattg cgtattatat cttggcaaaa gaacttgtca aagcaaataa
    42481 aggccacgag aaagcattga aggcgatgtt gaataattac aagaaatcgt atctatcgat
    42541 tggtttgaat gtgttaggaa ttgtcttagg gtatttagta gcgccagtag ccgtgctgat
    42601 cgcaaacatc gtgattctag ctgcttggat catcccaagt cgtaccatcg aatcacaata
    42661 tcggtaaaat gatccgtgtt taaaatttaa gagaaaaata tagaaaaaat aaataaacga
    42721 tcaaatatcc gagtgatact agtattcaaa gagggatgca gatggatcaa aaaagaattc
    42781 atgtaggact gattactagt tttgtcacga tgcttattta tttggatcaa ggtcatttga
    42841 cttggacagt agttggtgtc gtaggatttt tgacattatt cacagcaata aaaaaataaa
    42901 catctttatg taatctgatg ttctatctat ttaagaaaag catgtttaca gcagtatgat
    42961 tctgttgtaa acgtgttttt atttgtggaa aatttaattt ttagaaaagt gtatcgaaaa
    43021 atagatagtt agtttttcca cagtggataa cttcgtaaga gataaaaata aaaaattagt
    43081 caaagaaggg cgtatagatt tcttttgata ggagatatac aacagaaatg aataaatatt
    43141 aacgtgtttt caaacagtat aaaacggtgt ggtttttgga ataaaaaaat aacatatctc
    43201 attttacact tttgttattt tatacttaaa aaataacgac acagaaaata ccgtgtctca
    43261 gatttctcta ctacttctaa aaactactgt ttttttcctt tgaaatgcct tcaaaaagta
    43321 ggatcaggca gaatatactg gcagaatcaa ggagaaggga gcctaaataa ggagaaaaac
    43381 catagaaaat ataaagtaat tacttataaa acaagctttt tatagaaaaa taatatacct
    43441 gagtagggta taaattaaga cggaattcct ttctagattg agatattgac taggaagaat
    43501 gttaagattt taagccttta agctaaaaaa aaaccctttt tgttaaataa ggggaatata
    43561 gcctgtcagt ttcaaactgc aagtcgtcct gctgcaataa tatagtagat tagagatgaa
    43621 aatagatttt tttaaaccaa tgactgaata aaaagaccgt catagataca cattggaatg
    43681 tgtctattac ggtctttttt tacgaacgat tttattgaag acggacagtt cgggtcaaaa
    43741 ataaaaaagc tacgatcaga aataagaata aaatgtatcc caaaataatg gctagacggt
    43801 ctaacttatt tgtcgataga tgtttgttta gaagttgata ggcccataaa cctatcagtc
    43861 ctcctgttgt attagttatc aaatcagtga tgtccgctac gccaataccg aataggaatt
    43921 gaatcaattc tgccaagaag cttacaagga aaataatccc taatttttta gaaaaagaaa
    43981 gtctcttgaa attgacattc aaaagcaccc caaaaggaaa aaagacaatc aagttataag
    44041 tggtctcacg taataccgtc gtattttcaa aagaaaaagt agaaaaaggg acgagattga
    44101 cattgctgta agaataagtg agaaattgtg gaagattaaa tgatagcttg aataaaatca
    44161 accataatag aaagaataaa taaatcccta ataaaaattt tgatacatac cgcatagaca
    44221 tctcctccat ttaaaaagta taccatcgaa aaccgctgaa aaatcataaa aaagtatgaa
    44281 gtttaaggac caacgtagtt atcgtacgaa aattagaagc ttttttttgt tgggaatccg
    44341 gtttctttaa caaagctaag atagcgagtt gcttggaaaa gttgctatct tttttctgtc
    44401 aaaacgactc ggaatgttcg ttttttgttc taatttctcc aagttgttta ctttttgata
    44461 ctaagtttat gaaaaatcaa gaaatagttg ttatactagg taatgctgac aaacgggatt
    44521 ggcatttcat cttggttcag ctttttttcc aattactagg aaggagggat agattgttca
    44581 agacttattt tcgtttcaat aaaatacaag ataatccttt tcgtatcatg aatctgatgc
    44641 tacttatctt tattgtatta tggttaggtt acataaatca tgattttttg atttcaagtt
    44701 tttcatcatt agggatcttt acttttttct attatcaaaa cataccgatg aaatatttgc
    44761 tgaaacgtat gtttctgatc ggttgcggac tgttggttgc tttcgttttg gggatcttat
    44821 cgacttatgt tttatggctt gaaccatttg ccgtagcttt ggttgctttt tccagcagat
    44881 tcgtgttgcg attattccat atttctaaac caggtggctt gttttttgcg atgctttctg
    44941 ccatgggaac gagcatgcag ctgccaatcg ctcaattacc gatcgtctca ctttattttt
    45001 ttatgggtgt cgtttttgcc ctgattgcgg cagtgattac aaaattactg gattcacggc
    45061 ctgagcagac aattgaaaaa gcaactttaa aagaaagatt tcacgaagag cctttagtga
    45121 tcattgattc tgttttctac agcgctgcct tatttctttc cgtttatgtc agtcacggct
    45181 tgaatctgca taatccttat tggttgacct tgtcatgtgc atcgattttg ctagcagaaa
    45241 acttggatgc gatgaagcat cgacaagtcc aatatctgat tggatcgatg ggtgggttat
    45301 gtgtgtcggc attcttgtca tttgtgccgt ttacgcagtt gcagaccatt tttctgatca
    45361 cttttctata tggaatcgca caatttctag ttgctagaaa ttatgcagtt gctaatattt
    45421 ttcttaatcc gatggcgttg atgctatcta cacttattcg tggagcatac ttgatttctt
    45481 tgatcgaata tcgtttttta gggatcgtca taggaagttt catcggttta ggtgttgcgt
    45541 gggtaatgac ggttggtttg caacattatt taacggttgt tcgtcaaaaa ttagaataga
    45601 aggacaaata tatgtgccaa aagaggttat gacaagattt ttgtcacaac ctctaattca
    45661 aggtgttcaa aagccagatt ctcagcatta agtcaaattc acacaaaaat gtggaaagga
    45721 actttcaaaa aaattttata tttattctat caaaaaattt tgtttatgat ggtaactgaa
    45781 taaactttcc tgagatggtc aatgctttcc ttgaaagtct tacagatatt ctttcttcat
    45841 agaaagttta agttttatag ttagtgtaca ataaaagtat gtttatacca tatggtgtcc
    45901 ggataatcag tcatttaaac aatgaggttc aaagatatga aaaggggaaa tttgatgaag
    45961 aaaataagca atgaaatcca aattctggca gaaactttaa ctcttcccaa agtcgttata
    46021 gagcaaatga ttgtacaagc aaaaaacatc cttgatgagg tgtttgagca atatagtcat
    46081 gaactaatgg atcctaataa agcaaaggcg actgcaaaga aaatagacaa agtctatgaa
    46141 gaggaacctt ttgcagcatt agctatttat ctatatgcag cttctcaaag ttggaaaaaa
    46201 atttatcaac cattgaagat tccaagaact atctatttgg caacaatgaa tgcttttact
    46261 agatttattc atgaacattt ccaagtaaca ggaagctatc gctttgaccg tggtttttgg
    46321 atttggcatt acactagtgg cttgatcttt cggattggtg aattggagta cgaaatgaca
    46381 tattttccga aagggtacac ggatctaaga ttagaaggaa agcagtgcct ttctcttcat
    46441 attccttccg atgcagattt atctcagaat aagataagag atagttacga aagtgccatt
    46501 cgtttttttg aactttattt tcctgattac cattaccaag tgatgtacac agatacttgg
    46561 ttactatcac ccaatcttac taaatggttg aaaaaagagt caaaaatctg tctttttgca
    46621 gccgattatc gattattatc agttgatgaa caggacgata gtggagtccc ttggatcttt
    46681 ggacgagtag atgcccaaat acatgattat ccagaaagta cgagtttaca gcgacaagca
    46741 aaagagcaat tgcttgcagg cgagcacatt ggctctggct taggtattct tacttcataa
    46801 gtttagtact tcgaaatagt ttaaaagagc gtgagacaaa agtaaagaac acttttgtct
    46861 cacgctctaa acacgtataa acggcggaag cagaagcaac tccttcggaa ataagctgaa
    46921 attcacaaaa atttgaaaag caattttcgt gaatttcttc ttatttcttg gagttaaacg
    46981 cttctgtccc agcctctttt ttagtgttct atcgaacaca cagtacgttc aataggtaaa
    47041 ctagctataa caatagatat taaagttaac ggacaagagg gcctttttta ggtagctaaa
    47101 acgtaataat gaaaatttat ttccagagat aggagtcaat cagctagtct gatcgactgt
    47161 tttaacaagt tgactttcat tttaactttt gataccattt aaaacacaaa tcgtaattgt
    47221 ttcgatttgt gttttttagc atgactacaa tcaaagaaga aagtgggtcg tccatatgga
    47281 aaaaacagat atctcaagtg cataccgccg cttgaaaagc ccaaatatca aaacacgaaa
    47341 acgtgcgctg aagatcatca aagatgtgaa acggaatagt gggaaaaggt aagaagaagg
    47401 aaacttaatt aaaaaaatag ccgaaaaacg tttttcggct attttcaata atcggttttt
    47461 gtgtaaggtt tccgaaagaa ctgctgttga ttttccattt ttaacatatg ataaattggt
    47521 agaatctttc ttttcaaatt gataccattc cctaattcca gttatatagt taactacaga
    47581 accacaaagc acgtacgttt ataaaagtat tatctgtagt tatttttcaa ttccctttca
    47641 acctcttatt ttgaccagta gtattgatca ctttaccttt taacaccttt gttcgttttt
    47701 gaaacatttt tagtcaagaa tggaaacgta actacataat caaaggtttt gcgaaatatt
    47761 tcatgaaata tttcatgtag aagcgagcaa tacggttgca aataaccatt atcgtttaat
    47821 aagcagttac gaaagctccc aatatctcta acgttcagct cactccattt cttttcttca
    47881 aaaaaatcag tgattcgtat ctctttctat ttgtcgaaaa agttaacttt aaaaagtaac
    47941 gccgaaaaaa tatgcaaaaa aataaaaaag cagttactat t
//
LOCUS       DAMEEU010000012        47259 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.012, whole genome shotgun sequence.
ACCESSION   DAMEEU010000012 DAMEEU010000000
VERSION     DAMEEU010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 47259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.012"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            558..3197
                     /locus_tag="PB779_000722"
     CDS             558..3197
                     /locus_tag="PB779_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDE0738265.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(3365..4063)
                     /locus_tag="PB779_000723"
     CDS             complement(3365..4063)
                     /locus_tag="PB779_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDE0738266.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            4281..5426
                     /gene="tgt"
                     /locus_tag="PB779_000724"
     CDS             4281..5426
                     /gene="tgt"
                     /locus_tag="PB779_000724"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HDE0738267.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            5523..5903
                     /gene="yajC"
                     /locus_tag="PB779_000725"
     CDS             5523..5903
                     /gene="yajC"
                     /locus_tag="PB779_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HDE0738268.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            6208..8805
                     /gene="adhE"
                     /locus_tag="PB779_000726"
                     /gene_synonym="adhC"
     CDS             6208..8805
                     /gene="adhE"
                     /locus_tag="PB779_000726"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HDE0738269.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            9034..10140
                     /locus_tag="PB779_000727"
     CDS             9034..10140
                     /locus_tag="PB779_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDE0738270.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
     gene            10157..11185
                     /locus_tag="PB779_000728"
     CDS             10157..11185
                     /locus_tag="PB779_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HDE0738271.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLEGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            11191..11670
                     /locus_tag="PB779_000729"
     CDS             11191..11670
                     /locus_tag="PB779_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HDE0738272.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            11686..12981
                     /locus_tag="PB779_000730"
     CDS             11686..12981
                     /locus_tag="PB779_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HDE0738273.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            12992..13816
                     /locus_tag="PB779_000731"
     CDS             12992..13816
                     /locus_tag="PB779_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDE0738274.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPETP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            13981..14880
                     /locus_tag="PB779_000732"
     CDS             13981..14880
                     /locus_tag="PB779_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738275.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(15006..15875)
                     /locus_tag="PB779_000733"
     CDS             complement(15006..15875)
                     /locus_tag="PB779_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HDE0738276.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            16028..17488
                     /gene="rhaB"
                     /locus_tag="PB779_000734"
     CDS             16028..17488
                     /gene="rhaB"
                     /locus_tag="PB779_000734"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HDE0738277.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            17485..18741
                     /gene="rhaA"
                     /locus_tag="PB779_000735"
     CDS             17485..18741
                     /gene="rhaA"
                     /locus_tag="PB779_000735"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HDE0738278.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            18755..19600
                     /gene="rhaD"
                     /locus_tag="PB779_000736"
     CDS             18755..19600
                     /gene="rhaD"
                     /locus_tag="PB779_000736"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HDE0738279.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            19602..19913
                     /gene="rhaM"
                     /locus_tag="PB779_000737"
     CDS             19602..19913
                     /gene="rhaM"
                     /locus_tag="PB779_000737"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HDE0738280.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            19995..21146
                     /gene="fucO"
                     /locus_tag="PB779_000738"
     CDS             19995..21146
                     /gene="fucO"
                     /locus_tag="PB779_000738"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HDE0738281.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEVSVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            21273..22031
                     /locus_tag="PB779_000739"
     CDS             21273..22031
                     /locus_tag="PB779_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HDE0738282.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            22131..22775
                     /locus_tag="PB779_000740"
     CDS             22131..22775
                     /locus_tag="PB779_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HDE0738283.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            22782..23789
                     /locus_tag="PB779_000741"
     CDS             22782..23789
                     /locus_tag="PB779_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDE0738284.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            23805..24647
                     /gene="kduI"
                     /locus_tag="PB779_000742"
     CDS             23805..24647
                     /gene="kduI"
                     /locus_tag="PB779_000742"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HDE0738285.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            24667..25470
                     /locus_tag="PB779_000743"
     CDS             24667..25470
                     /locus_tag="PB779_000743"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HDE0738286.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(25719..26783)
                     /locus_tag="PB779_000744"
     CDS             complement(25719..26783)
                     /locus_tag="PB779_000744"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HDE0738287.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(26780..27865)
                     /locus_tag="PB779_000745"
     CDS             complement(26780..27865)
                     /locus_tag="PB779_000745"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HDE0738288.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="PB779_000746"
     CDS             complement(27878..28855)
                     /gene="mvaD"
                     /locus_tag="PB779_000746"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HDE0738289.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="PB779_000747"
     CDS             complement(28848..29792)
                     /gene="mvk"
                     /locus_tag="PB779_000747"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HDE0738290.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            30108..30767
                     /locus_tag="PB779_000748"
     CDS             30108..30767
                     /locus_tag="PB779_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDE0738291.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            30852..31757
                     /locus_tag="PB779_000749"
     CDS             30852..31757
                     /locus_tag="PB779_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDE0738292.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(31759..32391)
                     /locus_tag="PB779_000750"
     CDS             complement(31759..32391)
                     /locus_tag="PB779_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDE0738293.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     misc_feature    32542..32667
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            32711..33235
                     /gene="infC"
                     /locus_tag="PB779_000751"
     CDS             32711..33235
                     /gene="infC"
                     /locus_tag="PB779_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HDE0738294.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            33307..33507
                     /gene="rpmI"
                     /locus_tag="PB779_000752"
     CDS             33307..33507
                     /gene="rpmI"
                     /locus_tag="PB779_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HDE0738295.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            33560..33919
                     /gene="rplT"
                     /locus_tag="PB779_000753"
     CDS             33560..33919
                     /gene="rplT"
                     /locus_tag="PB779_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HDE0738296.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            34171..35508
                     /locus_tag="PB779_000754"
     CDS             34171..35508
                     /locus_tag="PB779_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HDE0738297.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAILCLITFLLYGNA"
     gene            35556..37685
                     /locus_tag="PB779_000755"
     CDS             35556..37685
                     /locus_tag="PB779_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HDE0738298.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKRQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            37660..38349
                     /locus_tag="PB779_000756"
     CDS             37660..38349
                     /locus_tag="PB779_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738299.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(38757..39370)
                     /locus_tag="PB779_000757"
                     /pseudo
     CDS             complement(38757..39370)
                     /locus_tag="PB779_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
     gene            complement(39506..39700)
                     /locus_tag="PB779_000758"
     CDS             complement(39506..39700)
                     /locus_tag="PB779_000758"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738300.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(39750..40190)
                     /locus_tag="PB779_000759"
     CDS             complement(39750..40190)
                     /locus_tag="PB779_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HDE0738301.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(40194..41039)
                     /locus_tag="PB779_000760"
     CDS             complement(40194..41039)
                     /locus_tag="PB779_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HDE0738302.1"
                     /translation="MLINEQLVKRVITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            41188..42606
                     /gene="pepV"
                     /locus_tag="PB779_000761"
     CDS             41188..42606
                     /gene="pepV"
                     /locus_tag="PB779_000761"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HDE0738303.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(42663..43610)
                     /locus_tag="PB779_000762"
     CDS             complement(42663..43610)
                     /locus_tag="PB779_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDE0738304.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(43833..44183)
                     /locus_tag="PB779_000763"
     CDS             complement(43833..44183)
                     /locus_tag="PB779_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HDE0738305.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            44383..45462
                     /gene="pepA"
                     /locus_tag="PB779_000764"
     CDS             44383..45462
                     /gene="pepA"
                     /locus_tag="PB779_000764"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HDE0738306.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            45606..45926
                     /locus_tag="PB779_000765"
     CDS             45606..45926
                     /locus_tag="PB779_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HDE0738307.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            45948..46412
                     /locus_tag="PB779_000766"
     CDS             45948..46412
                     /locus_tag="PB779_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDE0738308.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            46617..47222
                     /locus_tag="PB779_000767"
     CDS             46617..47222
                     /locus_tag="PB779_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HDE0738309.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT        14983 a         8602 c        10219 g        13455 t
ORIGIN      
        1 aaaaagccga gctctcgata agctcggctt tcttgtacct cggaaggatt caaataaaca
       61 gaaatgattg taactttcca tcatacatgc aaagcacggt gttgaatttc ttcatgttaa
      121 acaaaaattt tgttttcgtt acatcttcaa catttgaaac atctcttgtt cctattcaat
      181 tttcagacgt ttacgttatt caattgttac gtatcgcatt acttcttgtt tcggatactt
      241 cgtgatccaa acatccatac gcattcacta tttataggtt tgtactctac acgcatgtct
      301 gggtgaaacc tgtacttcta acaactttgt ttgcttacac tgttctatcg agaaattctt
      361 ctgtctattt gatggtatcc tccttcctta catctatata atagcatcct ttggtagcgt
      421 ttgcaaatat aagcacttta aattttacgc tttcttaaca aataatcgat aagcccttta
      481 tttgaagtaa ataaaaaaag gatgttatag taaaataagt accttttttt gtacgaagat
      541 tttaaaggag gaataggatg gaagaataca agcagacaat agaagaagta aagaaggtaa
      601 cagaagcaga tccagatact gggttgtctt cacaagaagt ggatgaacgg cgaaaaaagc
      661 agggattgaa taaattcgat gaggcgccga aagaatcgat gatcaaaaaa ttctttcgaa
      721 gcttgtccga ttttacaacg atcatccttc ttgtagcagc ggtgatttcc ttttataccg
      781 catttgctac agaacatggg gatttatttg aaggactgct gatcatcgct atcgttgtga
      841 tcaactcggt attggcgatt gtccaagaag gaaacgcaga aaaagcactg gaatccttgc
      901 aagatatgaa taaacaaacg gcaactgtca tacgagacgg caaagtgacc actgttgagt
      961 cagagcaact ggtagtgggt gatattcttg ttttagagtc cggtgatgct atttctgccg
     1021 atgcccgttt gatcgaagca tcacaattac gtgtagaaga atcggcgttg actggagaaa
     1081 gtgaagcagt tgaaaaagat gcagcattta ttgctgaaga agatgagtca ttaggtgacc
     1141 aacttaatat ggtatttaaa ggatgtacgg ttgctgcagg tcgtgggaaa gcgatcgtca
     1201 ctgccattgg catggctaca gaaatgggta agatcgcgga tcttttgaac gaaaatacta
     1261 tgcaaaaaac acctttacag gtccgattga atcagctagg caaacgaatc agtatgatcg
     1321 ctttagcggc tgcggcttta gtatttgtga ttggtgaact gcaaggagaa ccactccttg
     1381 agatgttcat gacttcgatt tccttggctg ttgcagctgt accggaaacc ttgactgtta
     1441 ttgttacgtt gacacttgca tacggtgtgc agaagatggc gaggaaacat gcgatcatcc
     1501 gacagttgcc agcagttgaa acgctaggaa ccgctaatgt tatctgctca gacaaaacag
     1561 gaacgctgac acaaaatgaa atgcgcgtcc gccgggtatg gagcaaagaa gatgaagtaa
     1621 cgaatatcga agattcaatg acgaacagcg cgatggaaat attgaaaatg gctgcactat
     1681 gtacagatgt gacggtcgag caagaagatg acgaccttgt tatcaaaggt aatccaacag
     1741 aagtagccat cgtaagggct gttgaagaga attatcatac aaaggcagaa ttagaagaaa
     1801 aatatccacg agtaaacgag cttccttttg attctgaacg aaaaatgatg acaacagttc
     1861 accaaatggg cgaaaaatac atctcaatca ccaaaggagc attcgatgtt cttgctccgc
     1921 gctttagttc aggcgatgta gaacaagcgg cgatcgttaa tgatcgcttt ggtaaacggg
     1981 cactgagagt gattgctgtt ggttatgcta cttatgacga agaaccgcaa gatatttctt
     2041 ctgaagcact ggaaaaagac ttacgtttga ttggtctgat cggaatgatc gatccaccac
     2101 gtccagaaag taaaggagca atcaagcgag cgaaaaaggc tggcatcaaa acagtcatga
     2161 tcactggaga tcatgtggtg actgccagtg ccatagcgaa agaattaggt atcttgaatg
     2221 atccgtcaga agcactttca ggatcagaac tgcatcaatt atcagacgaa gaattagatg
     2281 cgcgtgtcaa agctctctct gtctatgctc gggtaacgcc agaagacaag atccggatcg
     2341 tcaaatcttg gcaacgtacg ggtgcagtcg tagcgatgac tggggatggt gtgaatgatg
     2401 caccagcgtt gaaagcaagt aacgttgggt gtgccatggg gatcacagga acagatgtgg
     2461 cgcaaagtgc cgcagatatg attttgacgg atgacaactt tgcgacgatc gtagacgctg
     2521 tcagtcaagg acgttcggtt tatcagaata ttcgtaaagc tatcaacttt ttgctaagct
     2581 gtaatatttc ggagatcttt attgttttga ttgcgatgct gttaggatgg ggagcaccat
     2641 ttacagctgt gcaactactg tttgtcaatg tagttgctga tggacttcca ggatttgctt
     2701 taggaagaga gccagcggaa cacggcatca tggatcagcc acccattccg aaaaatgaag
     2761 ggatctttgc tcgaggttta ttgcaaaaaa ttgccataaa tgcaggggtc ttcaccatcg
     2821 taaccttgtt tggttattat ttaggtagtt atgtcgatac tatcagccca tgggtagacg
     2881 caagtcagca tgtcggtcaa actgttgcat tcttgatctt agcttattca tcgattctgc
     2941 atgtgttcaa tgtacgcagc agccaatcga tcttcaaagt caatttagcg accaataaag
     3001 ctttggtaga aatggcgtta ctggcattag ctattacaac ggctgttgct ttgctgccat
     3061 ttacgcaaga actattcggc ctagtacaca tcagtttgaa tcactggttc ttggtaggga
     3121 ttttatctat cgtaccaatc gcggtgaatg aactgatcaa gttccatcga ttaccggaag
     3181 cagaagaaga ggaatgatta actgtttcta agttgatttt ctttttactg gaactataca
     3241 aaaaggaggt gtgacatgaa tgttgtcaca cctccttttt gctaatgggc tgaatgtttc
     3301 ttttactgcc tctcgataaa cggtgttctc ctgccacccc ctcggtcaca agtcacactc
     3361 tcttttaaat atcttttggc aattgttcat aaaatgctgc ttttgttgca gaaatgtatg
     3421 ggctgagcca tagataacca ataccagcag ttgctaatgc taagatatgc cagccgataa
     3481 atgaaagatc taaccagaaa agttgtcctt tataaccatc catcaatttt cgacttgcag
     3541 tgatcgtatc cagtacttta ggtgtttgtc ctgtttcttg gacgatatcg tagtaaataa
     3601 aatagctttg agaataagaa tagcttttaa tgattccagg aataactaat agcaaacccc
     3661 ataatgttgt aaagatcgag atcagcacag ctaagctgat cactccgccg ataaacaaac
     3721 ctttgaatcc acgaaatgca tctttgaatg gttcgatctg atctttttgt ccacgtaaaa
     3781 tatcaagata agtccaagaa ataccgctca tgaacaaagc gctaatgatg ctggaaataa
     3841 ttccgccacc gcctcctgaa ctaccgcctc ctgaagttgt cgcttctgag acgctcgctg
     3901 atccatcata tatggtggtg gcaaacaaga taataggaat cataataaga agaatagtag
     3961 caataccaat caatgtaggg attagattta gtaaaacagc ttgtccccaa cgtcctttta
     4021 gactctcttt tgcttggcgt tttaattctg cagaagattg catgattttt ccctcctttt
     4081 ctttaataac accaatatac catgtatcaa aaaatatttc tgtcataatg tttttctttt
     4141 ttttgttatt cataaaaaaa ggataaaaaa aagaatatta aataaagtag aaggaagccg
     4201 agggaacttg caaaaagcac ttgaaacgat tatgatggtg ggagttgtca agatatttta
     4261 tatagaaagt agggaaatga atgacgcaac ctgccattcg ctatcgttta atcaagaaag
     4321 aaaaacatac tggcgcgcgt ttaggggaat tgatcacgcc acacggaact ttccccacac
     4381 caatgttcat gccagtagga acattagcta cagtaaaaac aatgtcccca gaagagttga
     4441 aagaaatggg tgctggcgtt attttaagta atacatatca tttatggcta cgccctggtg
     4501 aagacttagt agaagaagct ggcggactgc ataaatttat gaactgggat caaccgattt
     4561 taacagattc aggcggcttt caagtttttt cattaagtga tatgcggaat atcgaagaag
     4621 aaggcgtgca tttcaaaaat cacttgaacg gttcgcgtat gtttttatca ccagaaaaag
     4681 caatcaacat ccaaaataaa ttgggctctg atatcatgat gagttttgac gaatgtccac
     4741 cattcgatga aagttacgac tacgtgaaaa aatcagtaga acgtacgtct cgatgggcag
     4801 aacgaggatt gaaagctcat gctaatccag accgtcaagg attatttgga atcatccaag
     4861 gagcagggtt tgaagatctt cgtcgtcaaa gcgcgaaaga tctagtcggg atggatttcc
     4921 ctggttactc aatcggcggg ttatctgtcg gggaacctaa atcagaaatg aatcgtgtat
     4981 tagaattcac tacaccgttg atccccgaaa acaaaccacg ttacttgatg ggtgtcggtg
     5041 ctgctgattc attgatcgat ggtgttatcc gtggagtaga catgtttgac tgtgtcttgc
     5101 ctactcgaat cgctcgaaat ggcacatgta tgacttctca aggccgtcta gtagtgaaaa
     5161 atgcgaaata tgcccatgat ttccgtccaa ttgatgagaa atgtgattgt tatacatgta
     5221 aaaactatac acgtgcctat atccgccatt tgatcaaatg tgatgaaaca tttgggattc
     5281 gtttgacttc ttaccacaat ttatacttct tgttgaatct aatgaaacaa gtacgtcaag
     5341 caatcatgga tgataatttg cttgaattta gagaagcctt ttttgaagaa tacgggttca
     5401 ataaagaaaa cgcaaaaagc ttctaaagga aaatctttta aaaattaagt aaaaaactag
     5461 tgttatcagc atttttctgc taaagtgttt tttgtagata cagaattagt gaggtgaaaa
     5521 aaatgggaac attaccaatg cttgtgatgt ttatcgcgct attagcaatg tggtttttta
     5581 tgtcacgttc gcaaaagaaa caacagcaag aacgtcaaaa cttgttagat agcatgaaac
     5641 caggtgattc agtcgtaacg atcggcggat tacatggagt tgtttcagaa atcgacaatg
     5701 acaaacggac agttgtttta gactgcgaag ggatcttcct tgagtacgat cgtgcagcaa
     5761 tcaaaacggt caaaccaggg actgtcgtaa caaatgatgc aacgactact gttgaaacaa
     5821 cagaagaacc agctgagaca gttgaagtaa aaactgaaac aacagaaacg ctggaagaga
     5881 cagaagagaa ggaagaaaaa taagtatcaa agcttattta aagacgaggt agggcagaaa
     5941 gatgtcctac ctcatttttt attcaaaaaa gaaagagata agagcatggg atatattgct
     6001 caatattgaa taatcgggtg tgtcatataa ataataataa ataactttat atatttttct
     6061 atacaaacac ctgtaaataa agcaatttta tatttaaaaa taactgtgaa aaaaatcaca
     6121 aaaaagtgtt tacatagaaa aataaatatt gtatgatata catgtgaatt atttaacaaa
     6181 taaccatgac ccattaggag gataatgatg gctaaagtaa tagaaaaaga aaaaacgaag
     6241 acaattgacg tacaagcaat gattgatgat ttggcagaaa aagcaaatgc agcattgaaa
     6301 gaaatggaaa gctttgatca agaaaaagta gaccatatcg tgcatgaaat ggcaatggca
     6361 gctttggatc aacatatgcc attagcgaag atggctgtag aggaaacagg ccgcggtgtt
     6421 tacgaagata aagcaatcaa aaatatgtat gcgtccgaat atatttggca taatatcaaa
     6481 catgataaaa cagttggtgt gatcaatgaa gatgtccaaa aagggttgat tgaaattgct
     6541 gaaccagtcg gtgtggtttg cggagtaact ccaacaacga atccgacttc cacaacgatt
     6601 ttcaaatcaa tgatcgcgtt gaaaacaaga aatccaatcg tttttgcttt ccatccaagt
     6661 gcccaaaaat cttctgcaga agcagcacga gtggtacgtg atgctgctat cgctgccgga
     6721 gctcctgaaa attgtatcca atggatcgaa catccttcga tcgaagcgac ttctatgcta
     6781 atgaaccatc caggtatcgc gatcgtctta gcgacaggtg gagctggaat ggtcaagtct
     6841 gcttactcta caggaaaacc agctttaggt gtaggtccag gtaacgtacc agcttatatt
     6901 gaaaaaacag caaaaattaa acgtgcagtg aacgatttga tcgtttcgaa aacatttgat
     6961 aatggaatga tttgtgcttc tgaacaagct gtgatcgtgg ataaagaaat ctatgcagca
     7021 gtaaaagcag aattccaagc acaccaagtt tatatcgtaa aaccagatga attgcaaaaa
     7081 ttagaagatg cagtgatgaa cgaaggaaaa tatgcggtca atccatcaat cgttggacat
     7141 tctgcgatgg aaatcgcaaa attggcagga atcagtgtac caaaaggaac gaaaatgctg
     7201 attgctgaat tggaaggcgt aggcccagat tatccgctat caagagaaaa actttctcca
     7261 gttcttgcca tgatcaaagc taacaacacg gaccatgcgt ttgatttgtg tgaaggtatg
     7321 ttgaatcttg gaggattagg acatacagca gttatccatt cagaaaacga agagttgcat
     7381 gtcaaattcg gtcttcgaat gaaagcttgt cgtattttag tgaatacacc atctgcagaa
     7441 ggcggcatcg gtgatatcta taacgaaatg attccgtcat tgactttggg atgcggttct
     7501 tatggtaaga actctgtttc tcgtaacgtc tctgctgtaa acttaatcaa tgtcaaaact
     7561 gtagcgaaac ggagaaataa catgcaatgg ttcaaattac cgccaaaaat cttctttgaa
     7621 aagaactctc tattgtactt agagaaaatg gaaaacgttg aacgtgtcat gatcgtttgt
     7681 gaccctggta tggtccaatt cggttactgc gatacagttc gtgaagtatt ggcacgacgt
     7741 aaaaatgatg tgaagatcga agtcttctca gatgttgaac cgaacccatc gacaaatacc
     7801 gtatacgcag gaacgaaact gatggcagac ttcaagccag atacagtaat cgctcttgga
     7861 ggcggttctg caatggacgc agctaaggga atgtggatgt tctatgaaca cccagacaca
     7921 tctttctttg gtgcaaaaca aaaattcttg gatatccgta aacggacata taagatcgac
     7981 aaaccagaaa aaacacaatt cgtatgtatc ccgacaacat cagggactgg ttctgaagta
     8041 acgccatttg cggtcatcac tgacagtgaa acacatgtga aatatccgtt agcagattat
     8101 gcattgacgc cagatgtcgc aatcgtcgat cctcaattcg tcatgtcagt tccagcatct
     8161 gtcacagcag ataccgggat ggatgtgtta acacatgcaa tcgaatccta tgtttcagtc
     8221 atggcttcag attatacacg tggattgagc ctacaagcaa tcaagttagt ctttgactat
     8281 ttagaaaaat cagtaaaaac acctgatatg gaatcacgtg aaaaaatgca caacgcttct
     8341 acaatggctg gtatggcgtt tgctaacgca ttcctaggta tttgtcactc agtcgcacat
     8401 aaaatcggcg gggaatacgg gatccctcat ggacggacaa atgcgattct tttaccgcat
     8461 attatccgct ataatgcaaa agatccacaa aaacatgcga tgttccctaa atatgactat
     8521 ttccgtgcag atacagatta cgcagatatc gcaaaattct taggtctgaa aggcgaaaca
     8581 acagaggaat tagtcgaagc tttagcaacg gctgtttatg aattaggaaa atctgtcggc
     8641 atcaacatga gtctaaaagc tcaaggagtc acacaagaaa cactagatac aaccgtagac
     8701 cgtatggctg aattagctta cgaagaccaa tgtacgacag ctaatccgaa agaaccattg
     8761 atctctgaat tgaaacagat catcattgat gcttacaacg gataagcaaa agaaagcgta
     8821 gaaaaaagat aagaaaatag atgaaaaaga acttggaaaa cgttgtttct ccaagttctt
     8881 tttttaattt ccaagtaact gaaagttact tttgttattt aacatttagg tcaattttag
     8941 acagtttttg ttcaaaaagc gatatttata gtggacggta ttactgctat attaaggata
     9001 taaaatgaaa gcgtttaaaa aggtggcgta aagatgatta ttaaagaaga gatttttgta
     9061 cctaaagaat tagtgaaaga aaaaattgac ctgctcgttg aaaacctgac aacgatcaaa
     9121 gacgataatg gtgaattttt gttggacttt gatggactga aagtagatga caaaagctgg
     9181 acagtgtgga attggccaca aggtgtcggt ctatatggta tttataaaaa ttaccagatg
     9241 acaaaaaatc ctcgcgctta tcaagtggtc aatgaatggt ttgaggatcg tatggaagaa
     9301 ggcgctccgc ccaaaaacgt caatacaatg gcaccgctat tgactatggc ttacttgtat
     9361 gaagacacga aagattcacg ctatttgcct tatttagaac aatgggcaga atgggtcatg
     9421 aatgacatgc ctcggacaaa tgaagacggg ttacagcatg ccacatatgg accggaaaat
     9481 aagaatcagt tgtgggacga tacattgatg atgacagtgc ttcctttggc aaaaatcggg
     9541 aaactgttga atcgcccaga atatttagaa gaagctcgtt accagtttat gatccatatc
     9601 aaatacttga tggataaacg aacaggattg tggtatcacg gctggacgtt tgaaggaaat
     9661 cataactatg ccgaagcatt ttgggctcgt ggaaactgct ggttgacgat tgctattcca
     9721 gagatcattg aaatcttaga attatcgaaa gaagatgcat tgcgcaaatt attgatcgaa
     9781 acacttgaag cacaagtgcg tgcattaaaa acttatcagt ctgaaagcgg tttatggcat
     9841 acgttgttgg atgatccttc ttcttacgta gaatcttctg caactgcagg atttgcttac
     9901 ggtattttga aagcggtcca taaacgttat ttaccacaag aatataaaga agtcgcttat
     9961 cgtgctatcc aaggattgct tgaacaaatc gatgaaaaag gagaagttca aaacgtttca
    10021 atcgggacag gaatggggga cagtttagat ttttatcgga atatcggaat cacagcaatg
    10081 ccttatggac agtcgttaac ggtgctttgt ttgacagaat tgctcgtctc ttattgttaa
    10141 aagaaaggaa acccatatga aaaaaacatc actgctgttt gcagcaagtt cgcttagcct
    10201 aggtctgcta ggtctaagcg gctgcggaaa taattctagt gtggcaactg tcgcagatgc
    10261 agatgtaaat gagatagtta ccttgcgctt tgcttatgca agcaacagcc agccagtaat
    10321 tgatgcaatg aatgaatttg ggcgtttagt aaaagaaaaa acagatggtt ccgtacagat
    10381 ccagtatttc ccagatggac aactgggtgg agaacgtgaa ctgatcgaat tgacacagtc
    10441 aggagcagta gatttcacaa aagtaagtgc ctcagcgttg gaaagtttct ctaaagatta
    10501 ttcgattttt tcagttcctt atctattcaa tgatgaagaa catttcttta aggtgatgga
    10561 taatgaagaa ataatggagc caatctacca atcgaccaaa aatttaggat ttaccggatt
    10621 gacctattat gattctggtc agcgcagctt ttatatggta gacggtccga tccatacgcc
    10681 ggaagatttg gagggaaaga agatccgtgt gatgcaaagc gaaaccgcta tcaaaatggt
    10741 agagctttta ggcggttcgc ccgtacctat gggaagtgat gaagtgtaca cgtctcttca
    10801 atccaatttg atcaacggat cagaaaacaa tgaatttgtc ttgtatacag ctggacatgg
    10861 tggtgtggct aaatactatt cctatgatga gcatacacgt gtgccagata tcatcatcat
    10921 gaatgatgcc atcaaagaac agctaactga tgagcaggaa aaagccattg aagaagcagc
    10981 gaaagaatca acggtttttg aaattgaagc ttttgcaaaa gcaattgaag aagaaaaagc
    11041 tttagcacaa gaagaacatg gagtccaatt caatgatgta gataatacac cgtttcgaga
    11101 ggcagttgcc ccacttcatg atatattcaa aaacgatcct acctacaaag acctttatca
    11161 aaagatccaa gagcaaggag cgtagctgtg atgaaaatga ttttaaacaa ggtattagag
    11221 atcctgggag ctgttttgct tgttgggatg gtcgctgttg ttttatggca agtattttcc
    11281 agaacggttt taggaaatcc aaatacggtc acggaagagc ttgttcgatt cggtcttgtc
    11341 tggtttgcca tgttgtcttc cgcgtatgtt gtgggacaaa aagcacattt agccgtaacg
    11401 gttttaagtg aaaaattaac tggcaaaaaa agtaaaattt tagaagttgt tgttcaaagt
    11461 ttatttctgg tatttgctgc gatgatcatg gtgtatggcg gatggaatgc tgtcacattg
    11521 acaatggggc agatctcgcc ttctttaagt attcctatgg gatatgttta tctgtcagta
    11581 cctgtatcgg gggtactcat cattatctat agcctgatca atctaatcga tacattaagc
    11641 aacaagccag caattcaaga aaaaatataa aaatggagga ataaaatggc aatagaagcc
    11701 ggattagtgt tattttttgt atttgttgtg ttgcttgtat tagggatgcc gattgctata
    11761 agtattgcat tctcatcgat gatgacttta ttgttagtta taccgtttga tgtttctgct
    11821 tttagttcag ctcaaaaaat ggtgggaagt atcaatagtt tttcgctgat cgctattccg
    11881 tttttcgttc tctcgggcat tatcatgaat aatggaggga tagctaagaa actagtggat
    11941 tttgcgatgt tgttcgtcgg gcgcgtgccg ggggctttgg ctcatacgaa tgtgttaggg
    12001 aatgctttat ttggttccat ctctagctcg gccattgccg cttctaccgc gattggcgga
    12061 gtgttgatcc ctcagcaagt ggaagaagga tatgaccgga agtttgcgac agcggtcaat
    12121 atcgcgtcag ctccgacagg tatggtcatt cctccaagta ctgcttttat catgtattca
    12181 cttgttgctg gtggtgcttc gatctctgct ttgtttatgg gaggttatct cgtaggcgct
    12241 ttgtgggcgc taggaatcat gctagtagca ttcatcgttg ctaaaaagaa taaataccct
    12301 gttgtcgaaa aaggacagat ggctcatgct ggaaaaataa taaaagaggc gattcctagc
    12361 cttctattga ttgtcatcat tatcggtggt atcttgacgg ggatatttac agcagtagaa
    12421 gcttcagcga tagctgtcat ttactccctg ttgattgcta tgttttacta taaaacggta
    12481 aaactaaaag atatacctaa tatgttgttt caatcagtag caatgtcagg gacgatcatg
    12541 ttcttattgg ctacttcttc catgatgtct ttcgccatgg cgtttaccgg tattcctcag
    12601 gcaattagtt cgttgattat gggcgtaacg gataataaat ttattattct gttattagtc
    12661 aatcttgtgt tattactggt gggtatgttt atggatgtgg cgcctgctat cttgattttt
    12721 acaccaatat ttttaccaat cgtcacaagt gtaggggttg atcctgtaca ttacgggttg
    12781 ttttcaatca tgaatctgtg tgtaggctcc atcacgccgc cagtaggtac aggactatat
    12841 gtcggtgcaa gtgtaggagg cgtaaaagca gaggcaatgc tgaaaccgct tcttcctttt
    12901 tatggggtta tcttagtcgt cttgtttttg attacttact tcccgcaaat cgtcatgtgg
    12961 ctacccaata tgctgagtta ggagaatagt tatgttgaac attacaatta gaggacatga
    13021 tctttccgaa gtccaaacga tagaagatct tgcagaaaaa acaaaagaac aagggattca
    13081 tacactgcag ctcgccttag gtctttcgtt tcctgaaaca ccttctggcg caaatgagat
    13141 caattctggg atgggaaatt atgtcaaacg agttttagaa aagcaagaag tgaccgtagg
    13201 aattttaagt tgctatatca atatgattca tccagattta acgatacgac aagagttgct
    13261 gacaaagttc gagcagtatc ttcgctatgc ttcttccttt ggtgcgtcga tggttgcttc
    13321 ggaaactgga tgtgttttgc cggaaatcca atatacggaa gaaaatttca cagatgaagc
    13381 atttgctgaa gctgtgtccg ttatccgtcg cttggtaaaa gctggagaaa aataccaaat
    13441 gatggtgggg atagaaccag gtttgaatca tccggtgtat tctttagcaa gggtagagca
    13501 gctgatccaa gcagtagatt cggactatct aggaatcatt ttagatccga ccaatttgat
    13561 cacaagtagt gattatcaag aacaagtcca attggtagaa gaagcttttg aacgttttgg
    13621 tgaaaagata tgtgcggttc atttgaaaga ttttcgtgtc gaacaggaaa aaatcgtgcc
    13681 ggtaaatttg ggagacggtg tgatcgagta cacaaaaatc aaagaaatca tcatgaagaa
    13741 tcgtccgtac ctgtatgtgg ttcttgaaga aacaaaagat gatgggattc gttatggaag
    13801 aagtcttctt gaataatgta aagaagacgt tggttaacta atatttagaa tggagggggc
    13861 ggggctagaa gatgccacgt ctcttctttt ttataagagt atataaaagc agctcttttt
    13921 gattacaaaa aacgtggtat aataaaattg tgcataagtg aacaaaagga ggtgcggcac
    13981 atgctccaaa agaaaatcag cggtgaacaa gtcaatacga tggtttctga tcagtatgaa
    14041 atctatcatg tcaaagatgt cgtcagccaa aataaaacga tctatcatca tcatgatttc
    14101 tatgagatcc atgctacatt aaagggagaa gcgacttttt atttgaacgg acgacaattt
    14161 acgatcaaag caggaagtgt gctgctcatc cattccaatg atttgcatcg tatcgtccgc
    14221 caatcttcag atgtattcga gcgtgtctat atctttgtca ccccttcttt tctagaaagt
    14281 cgttccacgc catggtctaa tctatcggct tgttttcaac caatgggaga gaagaggagt
    14341 cgtgtattgc aaatagaaca ggaagtattg aagcaaaaat tatcatttat cgaccatcct
    14401 cctgataaaa aaatttacgg tgaagacata aaatatgaac aagctctggt agaatacttg
    14461 atttttctca atcaagttgt acaaaaagaa gagagtgcgc aagaacagaa tgctgtagtt
    14521 cctaatgagc gtgtggaaca aatgttacaa tatatctcaa aaaatttatc tcatccgctt
    14581 tctttagagg aaatggaaaa gcagtttttt gtcagcaaat accatatcac acgagaattt
    14641 aaaaagtaca ctggatttac gtttcatcag tatgtaatga agaaaaagct gatctatgcc
    14701 aagcacttgt tgcgagaata ccgcagctct agtgctgtat atagtaaaag tggtttttct
    14761 tcttatccgc attttctgaa agcattcaag agagagttcg gcataacgcc taaagaattt
    14821 ttgaaacgtg atacacagaa acagttggtt cattatgaac attttgaaga tgaacaatga
    14881 gaatgatcac taaaaaataa ccgcagtagc tgctgttgtt tacatagaag cagaaactgc
    14941 ggttatttta tttttatcta tatatttcaa aatattttga aaaaatgacg tacatattat
    15001 atgaatcagc tgaatttacg aaagtctctc ggcgatagtc ctgtttttgc tttgaacagg
    15061 cggctaaagt aagcaaaatt ctcaatccct atttcttcgg aaatcattcg aaccgtaaat
    15121 tctgtatacc gaagaaggtc tttagcgtaa gaaagttttt tgctgatcaa ataatcgatt
    15181 ggtggagaac cgataaattt ggaaaaatct ttgctcagct gatatttatt caataagaat
    15241 tgttgttcta attgatcaag tgtaatcgtt tctttgaaat gttcgtctaa gtattgcttc
    15301 agtttgtaaa cgtaggcggg aatatcctct tcttcgaaat ctagctgata cttttgcaaa
    15361 atcagttcat tcagcaactc gtggatagct acagaggact ggaaatcggt acgggcattc
    15421 gtgccttgtt gcatgtggat caattctgtg atcaaatggt ggatcttgtt ttctgatgga
    15481 tcccctgttg aatggaaggt gttatggccg tcttttgtga actcctgata aaatgattgg
    15541 acgttctgac cattcaaatg gatccaatcc atttcccatg gttcttcgct gatcgtttga
    15601 taacgctgat attcttggca gtcaataaaa aataagtctc cagcttttag ctgttgctga
    15661 ttatcattat atgtaagcga acctttgcca gacaaagtaa actttatcaa gtaagaaggt
    15721 aaatgtgctc gttcagtata gtaagggatt ggtgctttga agtaaccgat ttcttggata
    15781 taaaaaaata aattcctgct tctttgtgta ggcgtcaaga tcactctttt tgagtcttcc
    15841 gaccatgagt ggttggcttt ttcccagtaa tccatgtaaa cactcccaac ttgtcaagat
    15901 aatgcaatta tataccaaaa tagtgtgaag caaaatataa gattctgtat tatgatagca
    15961 ttgttaataa atgataacgc tttattaata aagtgctaat caacaataaa gtaaaagagg
    16021 tggagaaatg aatccaacat ttgttgccat cgatatcggt gcatcaagcg gacgactaat
    16081 gaaaagtacg agggatgcaa aaggttcttt gatcttggaa gaagtacacc ggttcaaaaa
    16141 cggctttcgg aacaaagacg gtcacgatcg ctggaagatc gattatctta tcaaagagat
    16201 tttgattgga tttgaaaaat taaagcagac agggattgat cgcctttttg cggggatcga
    16261 tacatgggca gtcgattact gtctgattga tgaacaaggg gatcggataa atgatccgat
    16321 tgcttatcgg gacaagcgta ccaatggagc agtagaacag ttttctgaaa tctattctct
    16381 agataagttg tatgagcaga cagggattca gatccagcct ttcaatacct tgttccaatt
    16441 gtttgctgaa gaaaaagaaa atttggcaaa agcacataaa ttgttactga tacctgatta
    16501 tttagggtat gtctttactg gtaacatggt gacggagaaa actaatgcat ctactatgca
    16561 gctgctgaat gcagggacaa aagaatggga aatagaactt cttgaaaaaa tcggtgtctc
    16621 gaaggaatta tttccaccat tgacagagcc gggaacgata ctaggagatc tgcaaaaaga
    16681 acaattttca aaatatgatt tgccagatgt gacctttatc acagtagcaa gtcatgatac
    16741 ggcgtcagct gtattaggaa cgccaggtca aggagaacgt tggggttata tcagcagtgg
    16801 gacatggtcg cttttaggga ttgaaacaaa gatcgccaat gtttctcgca atgctttttc
    16861 tgaaaattat acgaatgaat ggggtgccca taacacggtg cgttttttga aaaacatcat
    16921 ggggatgtgg ttgatccagg aagttgcccg aatgcaagag tacgagtaca gttatgcgga
    16981 attggcagag cttgctgcaa aagaaaaacc gctgcagcaa gtgatggaaa tcaatgaccc
    17041 tcgatttttg aatcccccaa atatgataga agagattcag caatactgtt ttgaaacaga
    17101 gcagccagtc cctgtctcat cgggagctat cgctcgttgt gtgtatgata atcttgctct
    17161 ttgttacgca caagagctga tcaaagtaga acacttaact ggaacgaaat tggaaaagct
    17221 gcacatcgta gggggcggat cgaataatcg tctactgaat caattgacag cagattatgc
    17281 cggaatcatt gtagaagcag gacctagtga agccacagca atcgggaatg ttgccatgca
    17341 aatgctcagt acaggtcagt tttcgaatat agaacaagca agaaatgtaa tcaaacagtc
    17401 gtttccatgt gaaacttttt acccagatga aaataagcaa aacacgatgg aatggtacgt
    17461 gaataaaatc aaaggagtaa tcgtatgaac acgattgaaa gaaattacga acaagcaaaa
    17521 gaaaaatatg caactatcgg tgtagataca gatgctgtac tagaaaagat acaggacatc
    17581 aaaatttcta tgcattgctg gcaaggagat gatgtcaaag gtttcttgac accggatggc
    17641 gaattgaccg gtggaatcat ggcgacaggg aattttccag gagccgcacg aacacctgaa
    17701 gagcttagac aagatctgga gaaggcttat tcgttgatac cgggcaaaca caaattgaac
    17761 cttcatgcta tctatttgga tacagaagaa tctgtcgatc taaatgaaat tgagccgaaa
    17821 cattttgaaa aatgggtaga gtgggcaaaa aaagaagaaa tcggtcttga cttcaatccg
    17881 actttctttt cgcatccaat gatgaaagac ggctttacat tggctcatcc agataaagaa
    17941 gttcgtgaat actggatcga acacgggaaa agaagccgca aaatcgcgga gtactttggg
    18001 aaagaaactg ggcaaacaag tatcaataac ttttgggtac ctgatgggat gaaagataat
    18061 ccgattgatc gttttacccc acgggaacgt ttaatggaat cactcgatga aatttttaca
    18121 gaagagttag atgaacggta tgtacaagat gcagtagaaa gcaaactatt tggtttaggc
    18181 gctgaagctt atacagtcgg ttcccatgaa ttttatatgg gttacgggtt gactcgtgac
    18241 aaacttgttt gtctagatgc tggacatttt catccaacag aagtgatttc caataaatta
    18301 tcttcattag ctttattcag caaaggaatc atgttgcatg tttcccgtcc agtgcgttgg
    18361 gattcagacc atgtggtttt gatggatgat gaattgcagg aaatcgctaa agaattagtc
    18421 cgtaacgaat tgttggaaaa aacaaatatc ggtctggatt tctttgatgc aacgatcaac
    18481 cgtatcgctg cttgggtcat cggtacgaga aatacacaaa aagcactgct gaaagctatg
    18541 ctggaaccag ttgagcgatt gaaagaaatg gagctggctt ttgactttac ttcaagaatg
    18601 gcttatacgg aagaattgaa agatttcccg tatgccgatg tatggaatta tttctgttac
    18661 aaaaatcaag ttccagttgg tttggattgg ctggaagaag tccaggaata tcaaaaagac
    18721 gtgttggaat taagaaaata ggagtgtggc tatattgaaa aaaatagata ttttacaagc
    18781 gccttatgtg aaagaaatga tcgaaacgac gtcgaatctt tatcgcttgg gatgggatga
    18841 aagaaatggc gggaatattt cttatttact aaaagaagaa gagatcacac cgttcttgga
    18901 tcctgaaaaa gtgatccgcc gcatctcgat gatttttgat gccagccgtt tagcaggatg
    18961 ctattttatt gtaactggtt caggaagata ttttaaaaat gtagcgagcg aacctgccga
    19021 gaatcttgga atcgttcgag ttgctgaaga tggcaaaaca ctggaacttt tgtgggggct
    19081 ggaaaacgaa tgccttccta caagcgagtt gccaagtcat ttcatgagtc atatcgcccg
    19141 tttagaagta gacccagata atcggatcgt tatgcattgc catgctagtc atctattagc
    19201 gatgagtttt acgcatgaat tagacgaacg ttcctttagt cgtacgctat ggcaaatgtg
    19261 tacggaatgc ttagttgttt ttccagaagg aatttccatc attccgtgga tggttccggg
    19321 aacaaatgag attggggaag caacagctga aaaaatgaaa gaaactcgat tggttttatg
    19381 gccacaacat ggaatctacg ggtcaggaaa agacatggat gaagtctttg gtttgatcga
    19441 gacagcagaa aaggcagcag aagtctatac gtacgtcaaa gcgcaaggac caatcttgca
    19501 aacaatcacg gacgaaaacc tgtggcattt agcagatgcg tttggtgtca ctccaaaagc
    19561 aggttatttg gaggaagttc atacgaaagc aggtgtctga catggtgaaa aaagcttttt
    19621 gcatgaaagt ttacccagaa aaacaagaag aatacaaaaa aagacatgat gaactttggc
    19681 cagaaatgcg tacagcactt cgtgaacacg gggtcatcga ctattcgatc tatcttgatc
    19741 cgagtacaag tttgttattt ggttacttag tgatcgaaga tgaaaagtta tgggaaaaaa
    19801 tggcaaatac atctatcaat caaaaatggt ggaagtacat ggaagatatc atggagacaa
    19861 atccagatgc ctctccagtc agttgggaat tgatgccagt ctttgaactg tagcaacaag
    19921 caactgggca accggttgct tggggttctt tcgtttttat tgtgaaaaaa aatacaaatt
    19981 aggaggaata gaaaatgagt aatcgaatga ttttaaatga aacatcgtat tttggaaaag
    20041 gagcgattga gtcgatcgtc cctgaatttc agcagcgagg attcggcaaa gcagctgtca
    20101 ttactgacaa aggattgatc gagcacggta tagcaacaaa agtaacagaa cttctagata
    20161 aagcagcaat cgcttatgct ttatacgacg ggatcgtacc taatccaacg atccaaaatg
    20221 taaaagatgg agtggctttt gttaaagagg cagaggcaga ctgtttgatc gcaatcggtg
    20281 gaggttcgcc aatcgatacg gcaaaagcca ttgggattat tttgacgaat ccagagtttt
    20341 cagacgtcat tagtttagaa ggtgttgctg atacgaaaaa tccatgttta cctatattag
    20401 ctataccaac gacttctgga acagcagcag aagtaacgat caactacgtc atcacagatg
    20461 aagtaaatca ccgaaaattt gtttgtgttg atcctcatga tatcccaatc gtcgcgttca
    20521 tcgacagcga tatgatgatg ggaatgccga aaaaattggc tgcatcaaca ggtatggatg
    20581 ctatgacgca tgctattgaa gggtttatca caaaaggcgc ttgggaaatg actgatatgc
    20641 tgcatttaaa agcaatcgaa atcatcggcc attctttgga agtttctgta gatggcgatc
    20701 aaaatgggcg agaaaaaatg gcattaggac agtatattgc gggaatgggc ttctcaaatg
    20761 tcggtttagg actggtacac gggatggctc acccgttaag tgcatggtac aacattcctc
    20821 atggcgtagc gtgtgcagca cttttgccaa ctgtcatgaa atataacaaa gaatatactg
    20881 gagaaaagta ccgtgagatc gctcttgttc tagggattaa aggagcagct gaaatgtctt
    20941 tagaagatgt aagagaagcg gcttgtggtg agatcgatcg gttgagcaaa gcggttggaa
    21001 tcccagaaac catttctgaa ttaggtgtaa aagaagcaga tattccagca attgcagaag
    21061 atgctttgcg agatgtatgc acaccaggaa atccaagaga aacgacagta gaagaaatca
    21121 ttgctttata tcaaagtttg atgtaaaaac gaagcggatc ttcaacatta aattgcctgt
    21181 aaagagaaat ggtagtttat atctggatat ctcttttaaa ttgatggtat ttccgctata
    21241 atttttctta taaagaaata ggagaatatt atatggaaaa taaaaagcct tatggaactg
    21301 tattgatcaa agcctctaaa atactagact atttagcgga aaaccaagat gtctctttgc
    21361 agacgatcgc aaagggtgtg ggaatgacct cttctacagt cttgaaaata ctagatactt
    21421 tgttgatgat cggctacgta aataaaaatt cagagaaaaa ctatcgttta ggtgcaaagc
    21481 ttattcgcta cgcgaataaa aacattgaac aaatcgattt ggtagagttg actttaccgt
    21541 ttttagaaca gctgcagcaa aagatcgatg agactatcca cttaggggta ttggacaaca
    21601 atgagatctt gtacgtgaac aaactagatc caaaacatca aacgatccgc atgtcttcaa
    21661 aaatcggaat cacccgacca ttatacaatt ctgcgatggg caaagccgta ttagcagaat
    21721 tcagtgaaga gcagtacact gattatcttg aaaagcatcc gttgatccct tacacagaat
    21781 atacgatcac caatgcatta cggttgaaaa aggaaatcca aacggtaaaa gaaacccaca
    21841 tcgcatttga cgatgaagaa atcgaacgtg atattttttg tataggagcc tcaatcgtga
    21901 aaaacgaaca aatcattggt gcatttagtg taagtatgcc gaaatatcgt ttaacagatg
    21961 agacaaaaga acaaataatc agtgccctca agcaaacaaa aagcgaaatc gagcaaagaa
    22021 ttcaaaaata atgaaaaaag cgtttgcaat ttttcttttc tgccgtataa tatgggtata
    22081 gatttccaag ttataaaata aaatttctaa ataggaaata ggtggagaag atgaaaaaaa
    22141 ttgatatttt atctcgattg aaaaacgccg gagtgattgc ggtggtacgc ggaaaaagca
    22201 aagaagaagc tttgaatgct tgccacgcaa tcatcaaagg tggtctaact ggtattgagt
    22261 tgacttttac agtccctcaa gcagatcaag taatcaaaga acttttgtca ttctacaaag
    22321 accaaccaga aatagtgatt ggcgcaggca cagtattaga cgctgtcaca gctcgcttgg
    22381 ctatcttagc tggcgcagag tatattgtta gcccttcctt tgatcaagaa acggcagaga
    22441 tgtgcaatct gtatcaaatt ccttacttac caggatgtat gactattacc gagatcaaaa
    22501 cagcgctgaa aagcggggta gatatcgtca aactatttcc tggaagcgct tatggaccaa
    22561 gtatcatttc tgccttcaag gcgccgatgc ctcaagtcaa tatcatgcca actggcggtg
    22621 tgagtctgga caatatgaaa gagtggttcg atgctggtgt cgtaacagtc ggagtaggtg
    22681 ggaacctttt agcacccgca gctacaggag attttgacaa agtaacggaa gtcgcgcaac
    22741 agtatgcagc aaaaatgaaa gaaatcaaga ggtagctgct tatgggaaaa gtagtgacac
    22801 tcggagaaat catgttgcga ttgtccacag agcagggaac ccgtatcgat tcaagtgaac
    22861 gattcgctgc ccattatggc ggaggggaag caaacgtagc aatttcttta gctaattacg
    22921 gacatgaagc gatttttgct acaaaagtac ctgataacgc attgggaaaa gcagtcaaaa
    22981 agcacttgca atgttatgga gtagatacga aacaggtatt atctggtgga tcaagactag
    23041 gtacttatta tatggaaact ggtagtggcg aacgcgccgc ctcagtgatc tatgatcgtg
    23101 ccggatcaag ttttgctgaa atggatcatt tggaatggtc gctagaggag ttattccaag
    23161 gaatagatat atttcatgtt tcaggaatca ccccagcttt gtctaaaaaa tggcaaaaaa
    23221 tgacgaaaca ggtgatagaa gctgcaaaaa aagctggctg cctgatcagc ttcgatatca
    23281 actatcgtgg aaaattatgg acacagcaag aagccagcga agtaatccat cagcttttac
    23341 ctttagtaga tatctgctca gctggaaaaa tggatgctct ttatttgtta ggtatcgaga
    23401 aagcgccaga agcagaagaa caacctctaa tttattatta tcaaaaaatg caggaaaagt
    23461 tcccgaatat tcaggtgttt tattcgacca agcgtaccgt tcattcagca agtgaaaatg
    23521 aattgaaggg gacattgtgg atgaaccatg aatatgtgga atcccaagtc catagaatca
    23581 ccccaatcgt ggatcgagta ggtggcggag atgcttttgc aggtggcgtg ctccatggga
    23641 ttttatccaa tatgtctccg caagaaatca ttgattttgc tacggcagct tctgccttga
    23701 agcatacgat ccatggggac tgcaaccaat ttagtcaaga agaagtcgca caatttttag
    23761 catgcggctc tggaaaaatc attcgataga aggagtagaa gaaaatgcaa gaaatggaaa
    23821 cacgttatac acacagtcca gaagatatcc gtcattattc aacggaacaa ttgagaaaag
    23881 aatttttagt agaaaaggta tttgaaccag ggaaaatcag tttgacttat acgcacaacg
    23941 atcgaatgat ctttggtgga gtgacaccta ctgaaaaaga attagaaatc acattagaca
    24001 aagaactagg tgttgattac ttcttagagc gtcgtgaact aggtgtgatc aatatcggtg
    24061 gaccaggatt catcgagatc gatgggcaaa aagaagaaat gaaaaaacaa gacggatact
    24121 atatcggaaa agaaacacga catgttgtat tttcttctca agatgctgaa aacccagcta
    24181 aattctatat tagttctgtt ccagctcatc ataaatatcc aaatgtaaaa atcagtatcg
    24241 accaagtaaa accaatggag actggtgaag gcctgacact gaatgaacgt aaaatctacc
    24301 aatacatcca tccaaatgta tgcgaaagct gtcaattaca aatgggttat acgattttag
    24361 aaccaggaag cgcttggaat acgatgcctt gtcatacaca tgaacgtcgt atggaagctt
    24421 atgtctactt tgattatgcc aatgaagata cacgtgtgtt ccacatgatg ggcaaaccag
    24481 atgaaacaaa acatttagtt gtagacaatg aacaagccat tatttcgcca agctggtcga
    24541 tccattcagg tgtaggtaca agcaattact cattcatctg ggcaatgtgc ggagaaaata
    24601 tcacctatac agacatggat atggtgcaaa tggatcaatt aaaataagca taagggagag
    24661 aaaatgatgg aatttagtat ggatatgttt cgtttagatg gaaaagtagc attagtcacc
    24721 ggtgctgtct atggtattgg atttgagatt gcacgctctt tagctacagc aggagcaaaa
    24781 atcgtattta ataacttgaa tcaagaatca gttgatgaag gtatagcgca ttataaagaa
    24841 gcaggcatcg atgcaaaagg ttatgtctgc gatgtgaccg atgaagaagc ggttcaagcg
    24901 atggttcaac agatcaaaga agatgtaggt tcagttgata ttctagtcaa caatgcaggg
    24961 atcatcaaac ggacaccgat gatcgaaatg gatgcggcag acttccgcca agtaatcgac
    25021 gtggatttaa atgccccatt catcgtttca aaagcagtta ttccggatat gatcgaaaaa
    25081 ggcggcggta aaatcatcaa tatctgctcc atgatgagtg aattaggacg cgaaacggtc
    25141 agtgcttatg ctgcggcaaa aggcggatta aaaatgctga cgaaaaacat cgcttctgaa
    25201 tacggtcaat acaatatcca atgtaatgga attggaccag gttatattgc tacaccgcaa
    25261 actgctccat tacgcgaaac acaagaaaac ggtgaacgtc atccattcga tcaatttatc
    25321 gttggacgta cgccagcagc acgctggggc gagccaatcg atttggctgg accatctgtc
    25381 ttcttggctt ctagcgcatc tgatttcgtt aacggccatg tcttgtatgt ggacggaggc
    25441 atacttgcct atatcggaaa acaaccttaa aagagcttta gtacactgtt tagtggagag
    25501 gttgtgaaat cagcggattg aacgaatacc gaaggacagc tgattaaaca tcatttattc
    25561 gaaaaaagag gctgggacag aagcatttaa ctccaagaaa taagaaggaa ttcacgaaaa
    25621 ttgcttttca aatttttgtg aatttcagct tatttccgaa ggagttgctt ttacttccgc
    25681 cgtttgtacg tgtttagagc gtgagacaaa agtgttcttt acttttgtcc cacgctcttt
    25741 tctgtgcgtc ttccatactt cactaagtcg atccctcttg cttcgcacca atccttcact
    25801 ggtccggaaa agatcagaga ttgttggtgt agggccgcgg tattcgttgc gccgaccata
    25861 gtataaagca gacgaagctc ttcttgccat tgcttcatca gtataatagt ttcttctacg
    25921 ccgtgattca tcagatgcgt cagtacggtt cctgaagtac ccacggcatt tgcgccgaga
    25981 caaagggctt taaatatgtc ataggcattg cggatacctc cggaggctag gatttccata
    26041 gaagtgtctg cttcatttgc ttcaagcaat gaagagactg tcgattgccc ccagtcagct
    26101 aaataactca gttcccgctt ggagcgacgg gcgttttcga tctgggtgaa gcttgttccg
    26161 cttcgaccgc tgatatcaac tgtatgaact cctaaagcag ctagatcatt gagcgtttct
    26221 cttgtcatgc caaaaccgac ttcttttacg atgaggggga cgtcaatggc tgtttgagtt
    26281 tcttgaataa gtactttcca attggtaaaa tcacggtctc cctcaggcat aaccaactct
    26341 tgaggtgcat tcaaatgaat ctgtaaggca tctgcgtgaa acaatcggat agcttctttg
    26401 gctctttcga cagaagtccc tgcaccgatg ttggcaatga ttttcccgtg aggatattct
    26461 tgtcgcataa tcgtataagt atcggctaaa gaagggactt tcaaggcagc gctgactgaa
    26521 ccagtggcaa tcatcaaatc tgcttctctt gcgacgattg caagatcttg gttgattttt
    26581 tttgtttttt cgcttccgcc agtcatcgca ttgatataaa atgggctgct tagtgtaaac
    26641 ccaactgcct gtgtacttag atcgacatca gaaactgcta tttgcggcaa agggttatgg
    26701 atgatccgta cgaagtcaaa ttcgtttttt tgtttatcat gaaaggcttt agctagtgaa
    26761 acatgttcgt cttttcgatt catcggtttt cctttctttg atcgctatag acatgtaacg
    26821 gcagtggagt gatttctgct ttttcccatg cactcattaa aggaagaatg ccagatttct
    26881 ggtcaacaat tacgattccg caatcgcccc cacctgcacc agaagatttt gcggctcctt
    26941 catactgttc agctaaatta cacaatttgt tcaaagcagg cgtttcgatg acgaccccag
    27001 tgattgcaga taaatcatgc agtaattgtc ggttttttcg aatcatctgt tggatcaacg
    27061 ttacattatt ttctttaaac cctttgatca tttcgttgac acattctgta ctatttttta
    27121 agaaaagctg ataagccacc attttatctt ctctcgaacg gtgaacttga tcgaccaaat
    27181 cagaagtaga ggcagggcta cccgtccaac caatcaataa acgtaaatct tcaggagcaa
    27241 tcaatggctc aatggataga cctggccaat ccagggcaag taactcactg atagaatgct
    27301 gagtttcttg ttcttggagc caaggatggt cgaaggttga gaaagcgatc cagccaccat
    27361 aacagctagc agcgatgtcg ccgcaggaac cattatcttg aactgctaaa ttggctagtg
    27421 ctgcaatctt gaaaatctcc aactgagata aattcaacgc gtaaaaaaca ttcaaggctt
    27481 tgaccgttgc aacggtcacg gcaccgctag aacccaatcc atatttccgg ccatttgaac
    27541 tgtctaactc acttgttact ttcagatcat aaaaggataa aagaatgttt ttttcttgtg
    27601 catacttttc agtcaagcga atagcagcaa ggatataatg aaaaggattt tcccgaatat
    27661 ctaaaactaa ttctccgttg cgtcttgtcc aacgtacagg catcccacta tattgtgcag
    27721 attggatact tccgactttt cgtgcagatt ctacagtgac tgtcacgaat tgatcgactg
    27781 cagcgataac tgctggatgg cctgtttcaa caactgcata ttctccggca atatagagtt
    27841 tgcctggtgc agatacttca atcataaaaa tctcccttta ttcaataatc gcaattcctg
    27901 gaccagcatg tgcagtaatt acttgttctt tgctaaataa tttggtaaat gtttcttgta
    27961 cctcagataa atggctgttt tccactaaaa ctttgacatt agggccagca tccatcgtaa
    28021 agtagcatgg aatgccttgc tttctcaatt gtcgcaccgc atccatcgct tttaagctgt
    28081 caggagacca gtaagtgaat ggaggctggg cagctaaagt cgttccatgc atttttagtc
    28141 cgtttctttc catcgtttct ccgagaagtt ggaaatcttt tgttttgatt gcttgtttca
    28201 attgatatag atccccttca acggaatcta accagccttg ataaaaactg gatgtttcga
    28261 ctgtccgacg catcccattt ctgctggaca cttctttttt ctggtcgttg atcaaaacga
    28321 aaaccattgc taaatcgtct tcgaaagaat cggaagggac tggcttagcg taagaactta
    28381 agtcgtcatg gcctttttcc cattcgacga aaccaccgaa aatacttcgg caagctgaac
    28441 cagacccgcg tcgagcaaat cttgaaagag agagatcatc taatccaagc ttaagagcag
    28501 tattgcaagc gcctgctaaa gcagctagcc cgctggcaga ggaggctaat ccagctgcgg
    28561 taggaacgaa attctgactg attactgaag cttttagtga gaggccggct tctttacgaa
    28621 aaaggtcaag aaactgactg actttttttg ttgctttttc gtcttgcaag gtgccatcta
    28681 gataaaattc atctaccata tagctatcag aaaagatgac ttctgtctct gtataaaatg
    28741 catccaatgt taacgaaagg ctgttgttca ttggaaggat gagttcttca tttttcttac
    28801 cccaatattt gattagagca atgttggtat atgcgcgtgc tttgccttta aacataggta
    28861 tgtactccta atccttgtat ccaagtttca gcagcacccg catcttcaag tgcttgactg
    28921 atttcttggg cttttgtttt tgtttgtgct aatgcaatca tacagccacc gcgtccaccg
    28981 ccagttaatt tggcacccaa tgccccggta tcttttgctg tttggatcaa tagattaaga
    29041 aaatcattgc tgattgtcag cttttccaga agtgattgtg attcatccat tgtctgtgcc
    29101 aacgtttctg gtgaattttc aatgattgct tgttttgctt gcttcgtcaa gtatcctaat
    29161 ttttggatca tttgtccagt ttcatgaggc tgggtttcaa agaggtgagc gacatctttg
    29221 acggcttctc ttgtttgtcc tttgattcct gtatcagcga caatcaaaaa agcatcgatg
    29281 ttcaaagaaa agtagtcgaa aggatgccct tttgtaaaat aaatcggctg caagctgcta
    29341 gtagcggctg catcgattcc actaggatta ccgtgggcga ttttttccga aagctggaca
    29401 ttttctaata gtatttcacg agacaaagga aatgctaagt aatcataaaa agcacgagtg
    29461 actgctgtgg cgactgcagc gcttgatccc attccacgtt cagcaggaat cgtgctttca
    29521 atggtcagtt gcaagttttt ttggatgtca tgctgttttt ttaagtgaat gaataatttt
    29581 ttgatatttt ttaatgcatg aggagcttcg gctaaatttc ctgaatagta ggaagaaacc
    29641 agttgatcgt ccattgcatc cagctcttca aggaatgcgg tgacttttgt tgcatagaaa
    29701 ggaaaggcaa tcgctggttc tccataaaca accgcgtgct cgcccatcaa tatgatcttt
    29761 ccgcttgatt ctccttggcc atagtttgcc ataatctaac tccttctcac gtaaaagtga
    29821 tttttaagca aaaaataaag cgcccaaaac gagttgcgct gcttcacgaa tttttttgtc
    29881 cactaagggt ctcaaaaaac attcctcctt tattttacta aaaccatctc agaagtaaaa
    29941 ctaagaatac gttttctaaa gaaaaaacac ttttttctta agaatttttt gacttttttt
    30001 cttctttgac tagaaaaaaa tacaattgac actactagat attgggggta tatttaaaaa
    30061 ggttggagtt aaacacaata tttagtgatg aagtgagctg gaggtaaatg agcgtgatcg
    30121 ttttagcagg tacaattggt gccggaaaat caagtttaac agaaatgatg gctgaacact
    30181 ttgatagtca ggcattttat gaatcgattg atgataatga agtcttgccc ttattttatg
    30241 caaaccctga acagtatgct tttttgctgc aaatttattt tttgaataaa cgttttgcaa
    30301 gcatcaaaca agcaatgaaa gatgacaata atgtattgga ccgttcgatt tatgaagatt
    30361 cactgctttt ccatctaaat gcagatctag gaagagcaac agaaacagaa gttcgtgtgt
    30421 atgatgaact gctggaaaac atgatggaag aacttcccta tgctgcccat aaaaaacatc
    30481 cggatttatt agttcatatt cgtgtatctt ttgatacgat gttggagcgt atcgaaaaac
    30541 gtggtcgttc gtatgaacaa ttgtcctttg atccaagtct atacgattat tacaaagaat
    30601 tgaacagacg ttacgatcaa tggtatgaag aatacaaaga aagtccaaaa atccaaatcg
    30661 atggagaccg ctataatttt gtggaagatc ctcaagcaaa agaagaagtc ttgaaaatga
    30721 tcgaagaaaa attagcagag attcgccaaa ccaaagtagc catttgattt acagttgctc
    30781 aaataaaggg taaaccttta tttgagcgac ttttttcttt atactggaaa caaatgtcag
    30841 gaggatagag tatgcgggaa aaacactatt ttaatcaaga ccgtaatttt tggatcaatg
    30901 tacagcaaaa cgatgtgcta gctgttaaaa acttaaaaga agaatatggc attagtgacg
    30961 agatgctgac ttattctcta gataaaaatg aacgggcgcg cgtagagtac gattcttttg
    31021 atgaagcgtt actgcttgta tcaaatgttc cgcaccagca aaaagtcgat aatcattatg
    31081 aaactagtcc tatcgctttt attttaaaag aagacggttt gtttacattt accacgccga
    31141 ataccgagta cgtgattcga ctaattcgat cgcttttgga acgaatgcca gacatgagtg
    31201 tatacagttt attgtttcgt acattgtttt tgatttctga ttcctttttt cctttaatcg
    31261 aggaagtgaa tagtgaacgt cagcggctta atctgaaatt aagagaaaaa acaacgaaca
    31321 agaatctgct gcaactttca gatttagaga tcggtttggt ttacttagtt acaggaacaa
    31381 aacaaaatgt agtactttta gaacaaatca aggcattggc tatttatcgc aagttgtcag
    31441 aaaaggaaaa agaagagttg gacgatgcgc tgatcgaagc acgacaagca gttgaaatga
    31501 cgaacttagc ttcgcagatt ttagaccagc tctctggcac ttataataat ttgctgaata
    31561 acaacttgaa tgacacgatg aaatttttga cggtctggtc gctgatcttg accgttccaa
    31621 ctattgtgac aggattcttc ggaatgaatc tccagttacc ctttacccat tccgttttcg
    31681 gatggggaat cgccttgatc atcagtttgg tcttatctat ttggatgctt attgcactgt
    31741 ggcggcggat tcgttgatct agtctttgat ctgcaaacca agggcttggg cgatcacaag
    31801 tgcttgctct tggttgacga ttagtcccgc caaagaatct tgagataaag cgattgctgt
    31861 gaagaaatta gtcgtaaagt ctaatccctt cagagaagtt cgaaaccagt tcgaaccggt
    31921 caactgattg tcagacaaaa aaaggttttt ccaagtgacc tcataaaatt cgctgtcttc
    31981 taattgacaa tgatcgaagg agacagcttt caagtttgta ctactaaagg aagccatcga
    32041 agcaatacaa tcagtgaaag tacagtctcg aagataactt tcggcaaaat tcgtacctgt
    32101 taatttacat tgatgaaaca cgacttggtg gaaactgcca ccaatccact ccagattgga
    32161 aaaatcacat ttttcaaaaa tgacattact gcattcaaaa tgacgtaaaa ctgttttttg
    32221 catcgtaagt ttttggatat gactctctct taataccata tttttggcat cgagatagct
    32281 ttggtcaccc ccgttgatca gaagaccaga gaagatctcc tcatcttcta aataaaactc
    32341 tccctttgta agaagaggaa gagaaggtgg aataggttcg atttttttca tgtgggttca
    32401 cctcgttttt ctttagtata gcaaagaagc gggaatcact gctagaaagt ctgctaatct
    32461 aatcattttc agaaaaggaa gacaaactgt atgaaaaaca ttgacaaaaa gattagtttt
    32521 tgctatacta tgatggttga gaaataaaag cagaagcacc cgcttctcgc cttagttgat
    32581 aatgtcactg ggctagatag ttttcactgg ttctattagg tgaagtacgc gcgggttctg
    32641 taagagaact cgttttttta ttgccgttta ttcggtaagc ttttctttct ctcataatat
    32701 ttggaggtga atgaccatag caaaggatat gatggttaac gacggcattc gtgcacgaga
    32761 gttacgattg atcggttcag atggtgagca attaggagtt aagacaaaag cagaagcatt
    32821 gaatattgca gaacaagcaa acttggatct tgtgttagtt gcccctggtg cgaaaccacc
    32881 agttgcgcga atcatggact acggtaaata ccgtttcgaa caacaaaaga aagaccgcga
    32941 agcgcgtaaa aaacaaaaag tgatcaatgt aaaagaagtt cgcttaagtc ctacgatcga
    33001 cttgaatgac ttcaatacaa aacttcgtaa tgcacgtaag ttcttggaaa agggcgataa
    33061 agtgaaagct tctatccgtt tcaaaggccg tgccattacc cataaagaaa ttggtcaaaa
    33121 agtcttgaat cgcttagctg aagaaactgc ggatattgca acagtggaac aaaaagcgaa
    33181 aatggacgga cgcagcatgt tcttgacgct ggcaccgaaa aacgacagta agtaatttga
    33241 atgactaact ggctgttgga cagccgatag tcggataacg aaagattttg aggaggaaat
    33301 atagtcatgc caaaacaaaa aacacaccgc ggatcagcaa aacgtttcaa acgtactggt
    33361 aaaggcggat tgaaacgctt ccgcgcgttt acaagtcacc gtttccacgg caaaacaaaa
    33421 aaacaacgcc gtcaattgcg taaagcaagc atggtttcta gtggcgactt caaacgtatt
    33481 cgccaacaac tagcaaaaat gaaataagaa gtacaaataa cagaatctga agatttattt
    33541 ttattaggag gaattataca tggcacgtgt taaaggtgga acagtaactc gtaaacgtcg
    33601 taaaagagtg ctaaaattag caaaaggtta ctacggttca aaacacactt tatttaaaac
    33661 agcaaaagaa caagtaatga attcatacaa ctacgcatat cgcgatcgtc gtcaaaagaa
    33721 acgcgacttc cgtaaattgt ggattgctcg tatcaacgca gcagctcgta tgaatggctt
    33781 gagctactca aaattaatgc acggtttgaa agttgctgaa atcgacatca accgtaaaat
    33841 gttagctgac ttggctgtta acgatgcagc agcatttact gcattggctg accaagcaaa
    33901 agaagctttg gctaaataag ctaaacaatt ataaagagga aagaagataa cgaaaagtta
    33961 tgttctttcc tcttttttta tttacaatcc tccatcaaat gaaacaggac aataacgtat
    34021 aagtctaaaa tagcataatt aaggtttttt aattgaaaac tgaacattta tggtcaccct
    34081 ttaatgaaag cgctaactac ataagttaga atgagtttga ctgatatatt agtttgctta
    34141 tcagaaaaac aaaatggacg gaggaataac atgagtgata ttattattgg tattttgtta
    34201 gttatctcat tctttttcat ggtctggtac tgtgtaaaag gctacaactt gatggtcggc
    34261 tttgccatca tggctactgt atggatggga ttagcgctag tcggaaacac gttttcacca
    34321 aacccggcga tggaagggca aggagtaatt gatgtgttga cgcatatcta tacgacgggg
    34381 ccagctgagt acgccaaatc gatcttggta aatgtcttct ttggtgcctt tttcgggcgt
    34441 gttctagtag atagcggaat cgcagctacc ctgattcgaa aggtagttga acttggaggg
    34501 gacaagccaa gaatcacgat gagcttacta tgtattgtaa ccgctgttat attcatgtcg
    34561 atgacaggaa tcggaccagt gatttctatt gcagttattg tgttgccaat cttgatgtca
    34621 ttaggtattt cagtaccggt tgcactgttc tcatttatgg gctcgattat ggctggaatc
    34681 tttgctaata tcgtcaattt caaacaatat caaacgattt atgctggttt caatccagcg
    34741 gctgaaagct atacttataa tgactatttc caaattggta tgattgggat gattgtaagc
    34801 ttagttgtgg tactaacggt cgctaatata tcaatgaaca aaaagaaacg ctatgcaatg
    34861 gcagcaaacg taccagctga aggtggcgac gcaccaatga tctcatggtt agccgtatta
    34921 ttaccagttt taggggtcgt tcttttagat cttccaatca tcttaggttt tattctagca
    34981 ggtatctggg cattgctgtt tactggaaaa ttgcgcggag gttataaaga aatctgtcgt
    35041 cagtttgcga aattatttac agatggcgca gtagatgttg caccaatggt tggtttcttg
    35101 atgaccttag cgatgttcaa taattcagct gcgtatgctt ctccttattt ttcagctatt
    35161 tttggagatt ggataccgca atcaccatta gtcttggcaa tcgtatttgc tatattgaca
    35221 ccactaggat ttttccgcgg tccaatgaat ctagtcggtt caggctcagc tattttagct
    35281 gtcgtattag ctgttaatcc aacgatgtcg ccagcctttt tgttcccgtt atttgcaatc
    35341 acaacgattg ctcctcagca tttagatatt acacaatctt gggttgcttg gggattaggt
    35401 tatacaaaag taacttctcg agaatatatg aagaaatcca tcccaactgg ttggatcatc
    35461 ggagcgatct tatgcctgat cacgttctta ttgtacggga acgcctagta aacaaaacgt
    35521 cgataaaaac gattagatga atggaggaaa agaaaatgaa acgttttgtg cgaatgggaa
    35581 ttgatgttgg cggtacacat acgaaagcag tcgcaatcga taatgcgacg cacgaaatca
    35641 tcggaaaatc ttcagtgaaa acaacccacg atgatgtccg tggagtagcc gcaggtgtcg
    35701 ttcagtcttt tcaaaattgt ttgcgggaaa ataatatcag tccagaagat gttgtgtttg
    35761 ttgcacattc taccacacaa gcgactaatg cactgattga aggagacgta gcaaaagtcg
    35821 gcgtaatcgg gatggcaaaa ggtggattag aaggtttttt agcaaaacga caaactagat
    35881 tgaacgatat cgatttaggg aataagaaaa aaatagagat tgtcaatgca ttcttacctg
    35941 tcaaacactt aaatgtagac cgtgtttcag aaacgatttc ttctttagaa agagaaagag
    36001 cggaggtctt ggtttcttct atggcatttg gagtagataa tggggaacca gaacgagttg
    36061 tttatgaagc agcatcggta aaatcgatcc ctacaacgat ggcttctgac atcacaaaat
    36121 tatatggatt gacaagaaga actcggacag cagcaatcaa tgcatctatt ttaccaaaaa
    36181 tgctagatac ggcaacctct acagaagatt ccgtacgaga agcaggggtc aatgtttctt
    36241 tgatgattat gcgcggagac ggcggagtaa tggaaatcaa tgaaatgaaa aaacgacctg
    36301 ttttaaccat gctttccggt ccagcagcat cagtcatggg ctctttgatg tacttgagag
    36361 cgtctaatgg tgtttatttt gaagtaggcg gaacaacaac caatatcggg gtcattaaaa
    36421 atggacgtcc agcaatcgat tattcaattg taggtggcca cccaacatat atctcttcat
    36481 tagatgttcg ggttctaggt gtggcaggcg gttcgatggt acgggctaat cagtcaggaa
    36541 tcatcgatgt cggtccacgt tctgcacata ttgccggtct agattatgca gtatttacgg
    36601 agacagaaaa aatcaaaggt cctaaggttg aatttttctc tcctaaagaa ggagaccctg
    36661 ctgattacgt caaggtagtg atggaagacg gagaagaagt gactattaca aatacatgtg
    36721 cagccaatgt ccttggatta gtgcaagaag aacatttttc ttatggaaat gtcccatctg
    36781 cacgaaaagc catccaagca ttagctgatt attgtcatac gacggttgaa gacatcgcag
    36841 aacagatcat ggaaaaatcc tatgctaaga ttgaaccggt gattttagaa ttggcagaca
    36901 agtatcactt ggagaaagat cagatttctc ttgtaggtgt agggggcggc gctgcctcat
    36961 tgattactta ctttagtaat aaaatgggtg tgaaatattc gattcctgaa aacgccgaag
    37021 tgatttcttc tattggtgta gcacttgcaa tggtccgaga tgttgtagaa cgtatcatcc
    37081 cttcgccaag taaagaagat atacgatcgt tgaaaaatga agcgatgaat aaagcgattg
    37141 aatcaggcgc tacaccagaa tcgatcgaag tccacgtaga aatcgatcca cagacttcaa
    37201 aagtaacggc tatcgctact ggttctacgg aagtgaaagc aaccgatcta accaaggaga
    37261 tcacaacaga agaagcacta gagcttgctg cagaggatat gcgattaaat aaaaatgaag
    37321 tttgcttatt ggaaaataca cctttctttt atgtatgcgg cgaacagaat cgttcaaaaa
    37381 atgctggaag tcttcggatc atcgatcaaa aaggatttat caaggtccaa cgtggacatg
    37441 cttcatgtat gaaaacaact gcagccaatt atatgacagc tgtcgaacaa ctttgggaag
    37501 atatggcagt ttatcaaact gaattgattg cccgaccaga attttatctc tgcttaggag
    37561 caagagtctc tgattttaca gcgacggatc tggaacaact acagcttttg atggatctgg
    37621 aagtatctac tatggaaccg gaggaagaag tgatcgtcgt tgccggaaat atcaaacaaa
    37681 cataagttag aagagttact aaacgaatta caacagatcc ccgaagaaat ttggggattc
    37741 taccagtttc ggcgagattt attttggaaa aagattcctt tgtccaagca gaaaattctt
    37801 atacaacaat caatcgattg tggtatcgaa acggcatgta gcatcaaaaa aaagtaccct
    37861 tttgccgatg taggagaaat ttgtgaacaa atggctgttc caatcgtttc ctgtgaatca
    37921 gagcaaataa acgaacgaat cacttttgca acttatgcag aagatgaagg gattcgattg
    37981 atgacggagc cgttagaaaa attaaaatgt tcaggactag cttcgatctc taaagaaaca
    38041 gcgcaagctt tgattattgg acatgaacta tttcaccaca tcgaagcttc tgttaaggga
    38101 atttatacgc aaagcgaaaa aattgtgctg tggcggttgc ctttttatac acatcaatca
    38161 aacattcgtg cattgagcga gatagcagcg atgagttttt caaaagagat gaatcaaagc
    38221 gatttttcgc cttatgtatt agaggcagtc ttactttggc catataatga aattcgtagc
    38281 caagggatct tagaagaaat aaaaaaaata gaaaaaagat gtacggagta tgatttagat
    38341 tacaaataaa gagactgtga caaaagtcgt gtcacagtcc tttttttccg aataaacgat
    38401 gttctcctgt caactcctcg gtcacaagtc aaaatattca acaaacatga gaagctgttt
    38461 tttgaaattg ttccttgtga ctcggagatg aacggcaggc tcacgacctc ttggaaaacg
    38521 gtgttcaaaa gcttgcatct gcggtaataa gtccagccaa gttaaaaaca taagaagcta
    38581 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctctcaataa
    38641 acggtgtgca atcagctgac cctcggtatt agctcaaaaa aaacggcaaa atatgaggaa
    38701 ctattttgcc gtttctttct ctaatactca ggtcaaaacg ctgattccaa aacctcttat
    38761 ttgatgggtc tgtcctgaat atcttcaaaa taatcggggt aattatgaat cacgtattct
    38821 tgctcctcga taatcatatg taaatgcatc gtgcaaagaa atccgacttc atcaaagtta
    38881 tgatcaatca ttgattgaag cattgtctga tgttcatcta atactcgacc ccagtctaat
    38941 tctgaaatcg tcaaacgtaa ccatctgaaa cggttcaagt gcgtactata actttctagc
    39001 caatcccaaa tttctcgttt tccagcaatt tcataacaag ttcggtgaaa atcagtatcc
    39061 aaatcaaaaa aagctttttt attttgagcg attactgcct gatcggtttt tccaactttt
    39121 cccgcgtata acgggctaat gaagcagatc ggatatcgat ttttgaaaca taagtgccgg
    39181 actgtggaat ggtttttaca agctcttgat tgcgcagttg gatcagtgct tctcgaatcg
    39241 gtgtacgccc gatagctagt tgttcttcta acactttatc ggagatttta cttccaggtg
    39301 ctaactcgga ataaatgatt tgtttacgta tagattcata agcttgctgt tgcaaattat
    39361 tgataaccat ttaaccttcc tttctatgca gatataatct attataacat aaatcgctta
    39421 caaatcgtgt gggcataaaa acacagtctg caaaaaaagc cctgataggc atgcctatta
    39481 gagcctcgaa aagaaaaata ttgaatcaat ctggtcgtac ctcttgtatc ggtttgacac
    39541 gaccgccgat tcttttagca aaagcttcgg attctttttt gtctttgaaa atgagcagat
    39601 tgtctaagtt tttttcccga gtgcgacagc cagttttatc gatgtaaccg tgcattactt
    39661 taacgacata catggggatc acctgctttt ttcttttcat tatacgaact actcgacaca
    39721 atacaagaaa aatgcttaga cggtctttat taagaattta catcatccaa agaagcgtac
    39781 gcttggaata actgatctaa ctccggattg actttgctca gcttcactaa tcgttgcgaa
    39841 tcagaaagta aaaaacagtg tttactactg ccagtagttt ttaatttttt gtcttcagtt
    39901 cccacaattt cgtagctaaa atccaaccgt gtccccgtat acttttggat agttggatgg
    39961 atgctcactt tttctccgta atggatcatt tctttatagc tgcaatttac ttccagaacg
    40021 gggatgatga tcccagattc ttcgattttt ttatagggaa accctagatg taccaataag
    40081 gctacccgag cctcttcaaa ccagcggata taattgctgt gatgaataat ccccatttga
    40141 tctgtttcat aataaaaagg ttctcgcaca taacctgtaa atttctccat gactcatgcc
    40201 tcgttttcca ttgatttttt acaaaaataa ttcatccatt tcggaagtgc ttcgctgatt
    40261 tgtgtcggca aaacaatata ttgttctttt gccagctggt ctccaatgaa actatgaaga
    40321 taaatagctg ctgcaatcgt ttggtcattt tgaggaaact gggctaaaaa tcctgtgatc
    40381 atcccagcta aagtgtcacc catgccgccc gttgccatag cagcagaacc taaaggattg
    40441 gtgtagaagt gctggtgacc ataaattttt gtctcatgac ttttcaaaac gagcacagca
    40501 ccgatttcct gttgcttctt tttgttttct ttatcccgtt gttcttgtat cggtagagaa
    40561 ctcaaccgtt gccactccat ttgatgaggt gtaagtacag tttgttcggg atagggtagc
    40621 aaaagatgat tagcagcaag taaacttaaa gcagagccat caatcaccag ccattgttct
    40681 tttgattggt tttctagtac ttgtttgaaa cgttccaaac tcttagaaga agtacccaat
    40741 ccgggaccaa tcaagagtac atctgcttgc tttattacgg aaagaaactg gtcagtatcc
    40801 gtccaaacta caatcattgc ttctggcaga tgactgtgaa gagcactccg atttttttca
    40861 tcagttacta cagtcgtgag acccgctccg ctgtgtacgg cagctaaagc actcataatg
    40921 attgctccgc catattgttc attgccgcca atcaaaacga tacgtccaaa tgttccttta
    40981 tgtgaaattt ttggacgagg tgtgatgact cttttcacta gttgttcgtt tatcagcatc
    41041 taaaaacctc cttttactca ttatagcgta tatttttttt agagaaaaac agataagaaa
    41101 aggaattgtc agattttttg aactattttt ttctgtaatt tgtggtatca tgaacacgaa
    41161 gacttaaata agtggaggat taactttatg acaattgatt ggcaaaaaga agtagaagca
    41221 cgtaaagaag acttgcttga agacttgaaa aatcttttac gtgtcaacag cgagcgcgat
    41281 gactcaaaag taacaccaga tgcaccattt ggacctggac ctcgcgacgc attgaaacat
    41341 atgttagctt atggcgaacg tgatggattt aaagtaaaaa atgtcgataa ctatgcaggg
    41401 catattgatc ttggcgaagg agacgaaacg ctagggatat ttggacacat ggatgtcgtt
    41461 cctgcaggag atggctggga cacagatcct tatgaaccag taatcaagga tggaaagatc
    41521 tttgcacgcg gatcaagcga tgacaaaggt ccaagtatgg cagcttacta tgcgatgaag
    41581 atcattaaag aacttgactt gaaactatca aaaaaagttc gcttcgtagt cggcagcgat
    41641 gaagaaagcg gctggggcga tatggcttat tatttcgaac atgaagaaga accagatttt
    41701 ggtttctcac cagatgctga attcccaatc atcaatggtg aaaaaggaaa tgtttcttta
    41761 gctttacgct tcaaaggcga caatgcagga gattatgtct tgaaatcttt tgtttccgga
    41821 cttcgcgaaa atatggtgcc aggaacagca actgcagcac ttcaagtacc aagtgcagat
    41881 gcagctatcg cgatggaaga agcattttac caattcatcg aagcaaatcc agtaagcgga
    41941 acgattgaag cggacaatac gtatgtaaaa atcgaattag ttggtaaagg cgcacatggt
    42001 gcaagcccac aatctggtat caatgcaggt tctttcttgg cattgttctt agataactat
    42061 gaattcctag gatctgctaa acaatttatc catgtagcag ctgcttatgt ccatgaagat
    42121 ttttatggag aaaaactagg agtcgcttat gaagatgaaa aaatgggcaa attgacaatg
    42181 aatgctggac tatttgcttt tgaagaaaat ggtacagagg aagcgaactt catcaatatg
    42241 aatttccgtt ttccaaaagg tgtaacagta gacggattgc aaagtgacat cgaacaaaca
    42301 gtggggcaag aaggcgcaac agttactcga ggtgctcgcg taatggaacc acattacgta
    42361 ccaatggatg atccattggt ggctacatta ttgcaagtct atgaagacca cactggagaa
    42421 aaaggctacg aacaaatcat cggtggcgga acttacggac gtttgttgaa acgtggcgtt
    42481 gcttatggag cgatgttccc aggatatact gatacaatgc atcaagcaaa cgaatttatg
    42541 agtcttgatg acttgttcag agcaacagca atctatgcag atgccatcta tcgtttggcg
    42601 aaataattaa ttaaaaagag gatcaagaat tgcaaattat ttttgcagtc ttgatccttt
    42661 ttttactttc tactgtggta ttcatgataa acatgatata gattcaattc atattctttc
    42721 ttagcgttcg tgacgactgt atccaaaatc aaccctgtta ctaatgaaag aagtgctaaa
    42781 gtcatcaatc cagtacttaa aatcgcagaa gggatgcgtg taataaagct tgtcagcata
    42841 tattcgcgaa tcacaggaat ccccgtgacc aatccaaata aaaagaagaa gatggtccaa
    42901 atcccaaaga aaagcaaagg cttataatct ttaaacattt taataatcat catgatcact
    42961 ttgaatccgt cagagaatgt attcaatttt gattcgctgc cttcaggacg atcacgataa
    43021 tcgattggga tttcaacgaa cttgaatttt ttatctaaag catggatcgt caattccgtt
    43081 tcgatttgaa aaccagaact cataatagga aaacttttga caaagatacg attgaatcct
    43141 cgatagccgg tcatgacatc aagaattttt gttttataca ttctagtaat tgtatttcta
    43201 acaaggttat ttccaaaatc gtggaaaggt ctcttattct catcaaagta ggttccattt
    43261 gataggcgat caccaatgac catatctgct tcaccagaac gtaatttctc gagcaaacca
    43321 tgtacagctt ctgcaggata agtatcatcg ccatctacca ttaaataata gtcggcatcg
    43381 atatcaaaga acatttggcg gatcacattt ccttttcctt gacgaggttc tttttttacg
    43441 attgctccac cttgaacggc caattcgtat gttcgatcgg tcgaattatt atcatagaca
    43501 taaatatctg cttctggtaa ttctcgttta aagtctgcaa tgactgttga aattgttgct
    43561 tcctcattgt aacaaggaat cagaacagca attttttctt gttgttccat ttttcactct
    43621 ccttaactat agaaaacaaa agctaaatta aaaatacctc ataatcaaag gaaatgctag
    43681 tttttcccgc taaatatcat ttatttaaaa agaaaatact ggaatatatg tttggaaagc
    43741 tctatctaaa aaaccaccca ctacaaaaga aggacatgat acctctcttt tgaatagtgg
    43801 gtgcgtattc gttctctcac ttttttgacg tattaatctg ttgcaccttt ttttcttgaa
    43861 atttctaata cggttcctgt atgagcatct gctaaaaatt cataataaac agtttcgcca
    43921 tcttctattc gagaaagacc tccccgataa gcactcgacc gaacggcgaa tttcctaata
    43981 ggttcctttt caaaagagat ccaagaacct tcgattgcac cttcttttag aaaagatgac
    44041 ttgatatttt caagtacttg gtctgctgac aatacttttt tgcgatgata ccaaatcgtt
    44101 gaagctaccc cgctcaataa tcctagaccg attccaactg ctaacccgcc tttaaaatag
    44161 cttagttcgc tttcttcata catgtggaca tacctccttc ttctcacttg ttactccttg
    44221 tgcttatttt accacactct catattttct ttgaaataaa taaccgctac cagaaaaaat
    44281 aagctataat aaatacgatc ggtctgcaga aaaaatcata ttttatccgc agatcaatat
    44341 aagtctgaga ggagtttagt ctgaaattta gacgaatagc atatggaaga aaaaacattt
    44401 caacgaatca aagagttaac agaattacaa ggaacaagcg gttttgaaca agatgttcgc
    44461 gcttatatgg aaagtcatat ggaaccgctg gtagatgagt tacagttaga tggtttgggc
    44521 ggcatttttg gtctgcgcca tcatgaagaa gcggatgcac cccgtgtaat ggtcgcagca
    44581 catatggatg aagtcggatt catgctgaca caaatccaag aaaacgggct ttttaaagtc
    44641 gtacctctag gcggctggaa tccttacgtt gtttctgctc agcgttttac acttaaaacc
    44701 tctactggta agaattatcc atgtatttct tcttccgttc ccccacattt attgcgagga
    44761 acaagcggac aaaaatcagt agaagtaacc gatattttgt tcgatgctgg gtttgaatca
    44821 agagaagagg caatgagtta cggtgtcctt ccaggagaca caatcgttcc ttacgctgaa
    44881 acgatcaaaa cagccaacgg aaagaatatt atcagtaaat catgggacaa ccgctatggc
    44941 tgtacaatgg tattagaagc tttagaagcg ttgcaaaatg aaacattagg tcatacattg
    45001 attgcaggcg cgaatgtcca ggaagaagta ggcttgcgtg gttctaaagc ttctgtcaat
    45061 aaattcaagc cagatctgtt ctttgcagta gactgctctg cagcagatga tacagtgacg
    45121 aaaaatggca cattcggaca tttaggagaa ggtacattga tgcgtatcca agatccaggt
    45181 ttgatcatgc ttcctcgttt gcgcgagtac ttgctggata tcgctgaaac aaacaatatc
    45241 ccttatcaat actttgtttc aaaaggcggt acagatgcag gtgctgctca tacacaaaac
    45301 gaaggaatcc caagtacagt gattggcgta gtgggacgtt atatccatac gcatcaaacg
    45361 atgttcagta ttcgcgattt tgaagctgca cgagaaatgt tgattcaaac actgaaaggt
    45421 ttggataaat caacagtgaa tacgatcgta tacggaaaat aatgcgatag tgaaactata
    45481 aaatctggca aaagattgct ttttgccaga ttttttttat aaaaagagga tcaatgtttg
    45541 ttagttcgaa agaaaggtgt ataatttaat tgaaaaatac ataaacagaa agtagaggac
    45601 aaagaatgat tatcccaaat agtttagaag aattagcagg ctacgtagaa actggaaaga
    45661 gtgtattttt ctttactgcc ggctggtgcg gagactgccg ttttatcaaa ccgcaaatgc
    45721 ctgaaattga aaatgacttt tctgattggc aatttattga agtagaccgt gacaagtaca
    45781 tagatgtagc cgctgaatgg aacatttttg gtatcccaag ttttgtcgtg atccaagacg
    45841 gaaaagaatt aggtcgtcta gtgaataaag atcgtaaaac aaaacaggaa atcgaatcgt
    45901 tcctagaaag tgtaacaaaa ggctgacatc tgttaggagg ggtcaagatg aatcaagaat
    45961 ataagaatat tttagtaggt atcgacggta gtgaacaagc acttgctgct ttcaaaaaag
    46021 cggtagaagt ggctcgccgt aataatggga aagtatatgt agcaaacgta atcgatcagc
    46081 aattttataa ctttatgggc tatgcaccta ttgatcaaaa tctagtcgat cagcaaactg
    46141 aaacagccaa ggaaatgatc gaagaatgta aagaatatgg gaaatctgtt gattacacaa
    46201 atatagaagg aattattgca tatggttctg ttcgtgaatc catggcagtc aaattgccaa
    46261 aaaaatatga gatcgatcta atcatggttg ggcagtcagg tctaaatgca gtcgaacgct
    46321 ttatgacagg aagtgtagcc agctacgtga tacgtcattc accttgtgat gtcttgatcg
    46381 tttctgacga agaagaacag ccaagtaatt aagcaagtgg aacttgtacg acctttttaa
    46441 tcaattaact aaaacagtaa agggactgtg acaaaagtct tgtcacagtc ccttgttacg
    46501 aataaatggt gttccagaag aggcttcttc ggaaataaag catgaaaaaa atttcatgca
    46561 gtgaatgcaa ttttttgtta agataaatct cagcaaagga taatggagga aagaacatga
    46621 tttttgctta taacaaagca cacgtcggag acaccttgat ggttattata gccgacgata
    46681 aaggaacaga aaacactgtt gaacgcaaat ggaatgttgc tcggatcaaa gatgaacaag
    46741 gtcaagttgt tgcttggaac tttttccata tctccgatca tctaacaatc gaagggaacg
    46801 gccaagtaag cttaacagat gaggaattag cgaaattgaa tcgattgatc aaagaagcag
    46861 gattcgaaga acagcttgaa gctgatcatg aaccgaagat cgttgtcggg tacgtaaaaa
    46921 catgcgtccc acatcctgat tctgaccatt tatcgattac tgagacagaa gtagacaatg
    46981 gtacagtatt gcaaatcgtt tgcggtgcac ccaatatcga agctggacaa aaagttgtcg
    47041 ttgcaaaacc aggagctatg atgccagatg gaatgatgat ctggccagga actttgcgag
    47101 gggtagatag ctatggaatg atctgttccg ctcgtgaatt gcatttgcca aatgctccag
    47161 caaaaaaagg aatcttagta ttgcctgagg atgccgtagt cggagaagca tttccaaaat
    47221 aaagaggttg tgacaagtct ttgtcacaac ctctttttt
//
LOCUS       DAMEEU010000013        46726 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.013, whole genome shotgun sequence.
ACCESSION   DAMEEU010000013 DAMEEU010000000
VERSION     DAMEEU010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 46726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46726
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.013"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            98..649
                     /locus_tag="PB779_000768"
     CDS             98..649
                     /locus_tag="PB779_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDE0738310.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            complement(802..1275)
                     /locus_tag="PB779_000769"
     CDS             complement(802..1275)
                     /locus_tag="PB779_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDE0738311.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            1413..2885
                     /locus_tag="PB779_000770"
     CDS             1413..2885
                     /locus_tag="PB779_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDE0738312.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2882..3592
                     /locus_tag="PB779_000771"
     CDS             2882..3592
                     /locus_tag="PB779_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HDE0738313.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            3944..4228
                     /locus_tag="PB779_000772"
     CDS             3944..4228
                     /locus_tag="PB779_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HDE0738314.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(4545..4928)
                     /locus_tag="PB779_000773"
     CDS             complement(4545..4928)
                     /locus_tag="PB779_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HDE0738315.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIK"
     gene            complement(4930..5514)
                     /locus_tag="PB779_000774"
     CDS             complement(4930..5514)
                     /locus_tag="PB779_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HDE0738316.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(5561..7036)
                     /locus_tag="PB779_000775"
     CDS             complement(5561..7036)
                     /locus_tag="PB779_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HDE0738317.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPAMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            7217..7528
                     /locus_tag="PB779_000776"
     CDS             7217..7528
                     /locus_tag="PB779_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738318.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(7643..9979)
                     /locus_tag="PB779_000777"
     CDS             complement(7643..9979)
                     /locus_tag="PB779_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738319.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            10121..10789
                     /locus_tag="PB779_000778"
     CDS             10121..10789
                     /locus_tag="PB779_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0738320.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            10792..11835
                     /locus_tag="PB779_000779"
     CDS             10792..11835
                     /locus_tag="PB779_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0738321.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(12072..12953)
                     /locus_tag="PB779_000780"
     CDS             complement(12072..12953)
                     /locus_tag="PB779_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0738322.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            13112..13840
                     /locus_tag="PB779_000781"
     CDS             13112..13840
                     /locus_tag="PB779_000781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HDE0738323.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            13996..14313
                     /locus_tag="PB779_000782"
     CDS             13996..14313
                     /locus_tag="PB779_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDE0738324.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            14306..14914
                     /locus_tag="PB779_000783"
     CDS             14306..14914
                     /locus_tag="PB779_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HDE0738325.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLIWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            14969..15760
                     /locus_tag="PB779_000784"
     CDS             14969..15760
                     /locus_tag="PB779_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HDE0738326.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            15898..16386
                     /locus_tag="PB779_000785"
     CDS             15898..16386
                     /locus_tag="PB779_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDE0738327.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            16437..17309
                     /locus_tag="PB779_000786"
     CDS             16437..17309
                     /locus_tag="PB779_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDE0738328.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            17485..17847
                     /locus_tag="PB779_000787"
     CDS             17485..17847
                     /locus_tag="PB779_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDE0738329.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            17856..18608
                     /locus_tag="PB779_000788"
     CDS             17856..18608
                     /locus_tag="PB779_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738330.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            18622..20424
                     /locus_tag="PB779_000789"
     CDS             18622..20424
                     /locus_tag="PB779_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738331.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            20701..21741
                     /locus_tag="PB779_000790"
     CDS             20701..21741
                     /locus_tag="PB779_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDE0738332.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(21793..23937)
                     /locus_tag="PB779_000791"
     CDS             complement(21793..23937)
                     /locus_tag="PB779_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDE0738333.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(24294..25667)
                     /locus_tag="PB779_000792"
     CDS             complement(24294..25667)
                     /locus_tag="PB779_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0738334.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(25667..26062)
                     /gene="rbsD"
                     /locus_tag="PB779_000793"
     CDS             complement(25667..26062)
                     /gene="rbsD"
                     /locus_tag="PB779_000793"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HDE0738335.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(26090..27007)
                     /gene="rbsK"
                     /locus_tag="PB779_000794"
     CDS             complement(26090..27007)
                     /gene="rbsK"
                     /locus_tag="PB779_000794"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HDE0738336.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(27115..28128)
                     /locus_tag="PB779_000795"
     CDS             complement(27115..28128)
                     /locus_tag="PB779_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HDE0738337.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(28209..28808)
                     /locus_tag="PB779_000796"
     CDS             complement(28209..28808)
                     /locus_tag="PB779_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDE0738338.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            28994..29695
                     /locus_tag="PB779_000797"
     CDS             28994..29695
                     /locus_tag="PB779_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738339.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            29705..32416
                     /locus_tag="PB779_000798"
     CDS             29705..32416
                     /locus_tag="PB779_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738340.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGPIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            32867..34495
                     /gene="treC"
                     /locus_tag="PB779_000799"
     CDS             32867..34495
                     /gene="treC"
                     /locus_tag="PB779_000799"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HDE0738341.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(34555..35736)
                     /locus_tag="PB779_000800"
     CDS             complement(34555..35736)
                     /locus_tag="PB779_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDE0738342.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            35988..37511
                     /locus_tag="PB779_000801"
     CDS             35988..37511
                     /locus_tag="PB779_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDE0738343.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(37580..38308)
                     /locus_tag="PB779_000802"
     CDS             complement(37580..38308)
                     /locus_tag="PB779_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0738344.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(38321..39601)
                     /locus_tag="PB779_000803"
     CDS             complement(38321..39601)
                     /locus_tag="PB779_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDE0738345.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(39742..40344)
                     /locus_tag="PB779_000804"
     CDS             complement(39742..40344)
                     /locus_tag="PB779_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDE0738346.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            40589..40795
                     /locus_tag="PB779_000805"
     CDS             40589..40795
                     /locus_tag="PB779_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738347.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            41107..41826
                     /locus_tag="PB779_000806"
     CDS             41107..41826
                     /locus_tag="PB779_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDE0738348.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(41907..42590)
                     /locus_tag="PB779_000807"
     CDS             complement(41907..42590)
                     /locus_tag="PB779_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HDE0738349.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            42809..44995
                     /locus_tag="PB779_000808"
     CDS             42809..44995
                     /locus_tag="PB779_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HDE0738350.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNIAVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
     gene            45341..45751
                     /gene="spx"
                     /locus_tag="PB779_000809"
     CDS             45341..45751
                     /gene="spx"
                     /locus_tag="PB779_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDE0738351.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
     gene            45765..46121
                     /locus_tag="PB779_000810"
     CDS             45765..46121
                     /locus_tag="PB779_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HDE0738352.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
BASE COUNT        15225 a         8207 c         9344 g        13950 t
ORIGIN      
        1 catctcctta taaattaaaa catgtaataa actacatgtt ttcgattact catttatgat
       61 agaatggatt taaagatttg tcaaggaggg aaaactgatg gcaagaaaaa atacacttcg
      121 atatattttg ttagggttat taagtaagaa gaagatgaca ggatatgaat tgaatcaatc
      181 gttcaaaaat gaaataggag aattttggca agcaaaacat agtcagattt atcctgaact
      241 tgcaaaaatg gaagagcaag gaatcattca gcatcaagta gagatcacag gtgaaaaatt
      301 ggaaaagaaa gtttatgaat taacagaaga agggaaggaa caattggcag agtggattca
      361 tacacccacc aatgaactac cggttaatcg agacgaattt gttctgaaat tgtatttcgt
      421 caaagacgtg aatgatccgg cattagtaga aattattcag cagcagcgtg accttcatga
      481 agaaaaacga cttcatctat tagagcgaaa aaaaacgatc tttcctactg aaaaagaaaa
      541 acatgaaaat tacggacact acctgatttt agcgcatgcg atcaatcggg aaacagaata
      601 tgcaaattgg ctaacagatg tattagaaga aagtaaccga aaaaaataaa aaaatatccg
      661 aacagtgatg gagaattcct ttctatatga aagaaacgca gatcaccgtt cggatattct
      721 tatgttcaaa caggcctttt ttcaagtatt tatgtagcat ctacttatta aaaagcttgg
      781 tacttaggag attagtggcg tttagagttc ttttaacaac tgttcgtagt cagctttttc
      841 atcgacagga aggagcttgt aagttaattc gtctgtctcg ttgtcatgaa tgatgtacat
      901 cttagcattc tcttctttga agttaccgat ttgtaaaatc gtatagcgtt cgtcgatcaa
      961 ttcgatatct ttgattgctt ttgaaaaaac tttacggaca tggtgcattt tcttttggcg
     1021 gatttctgcc ttttctgcag cttttgacaa agtaaatccg tcatctaaat attttttgat
     1081 cagttctact tttatgactg taggtaaacg atattttcta ggacaattcg catcagcttc
     1141 gatcgaacga atgaatccct tttgttccca ataccttaat tgacgtggag acacacctac
     1201 gatatcactt aattcactga tgccaacaac caattgatca ttttccaaca aacgtttaag
     1261 ggaagcccca accatttttg tcactccttt tgtcctcttg cttcccttaa ttatatccgt
     1321 attaacttat gtgtcaagta ggttgacaaa tagcgaattt aggactaaag tattctagta
     1381 gtttcagaaa aaattcagaa agaaggagaa atatgagtaa caaccaaccc gtagatattt
     1441 acggaaaacc atataatcgg acacttttag ttgttgtctt attaattggt acattttgta
     1501 ccgttttgaa tcagacctta ttgacgacag cttttcctac attgatgaaa gctttcgata
     1561 tttcagcgtc tgatgtgcaa tggttaacga ctggtttctt gctagtcaac gggatcatga
     1621 tcccaataac agcatggctg atcaataaat tcagttcaag aaatttatat ctttctgcca
     1681 tgacgatctt tttgatcgga acgattactt gctttacagc acctaatttt agtacattac
     1741 taatcggtcg tttgatccaa gcttgcggtg tgggagtatc gatgccatta ttgcaaaata
     1801 tcatgctatc tattttcccg ccagaaaaaa gaggatcagc aatggggatg tcagggatcg
     1861 ttattggact tgctcctgct ttaggcccta cattatctgg ttatatcatt gataactacc
     1921 attggcgtga cttgtttggt atggtactgc caatcgttgt tcttgtcttg gttttagcat
     1981 tcttcctaat gaaaagtgtt attccattgt caaatcctag cattgatatt ttatccgcta
     2041 ttttatcaac gattggattc ggtagtttac tttacggatt ttctagtgta ggagatgacg
     2101 gctggggaag cttgaaagta attggtttct tagttgttgg tgtgattttc atcgccttgt
     2161 tctcatggcg tcaattacat ttggaacatc cattcttgga acttcgtgta ttcaaatcat
     2221 ctacattcac gattgcagct gttttagctg gtgtaacaaa tatggcgatg gtaggggcag
     2281 aaatggtcgt accattgtat attcaaaata ttcgtggaga atcagcattc cattctggct
     2341 tgatgttgtt gccgggtgca ttgatcatgg gggctatgat gcctgtgacg ggtgcgattt
     2401 tcgataaata cggcgcgaaa cgtttagcca tcacagggat gttcattttg acagcggcaa
     2461 ctgcaccatt tgctttcttg acaaaaacga ctccagtttt atatatcgtg atcctttatg
     2521 cgatccgtat gtttgggatc tccatggtca tgatgccggt aacgacttct ggtatgaatg
     2581 cattgccaaa taacttgatc agtcatggga cagcggtaaa taatacattc cgtcaaatcg
     2641 caagctcgat tggtacagct attttgatca gtgtgttgac gaatgtgaca aaagcaaata
     2701 tcccaagcaa atctgtattg gataatacgc cattagctta taaagatcag gcaatcaatg
     2761 ccacactgtc aggttaccat gccgcgttta tcgtagcgat catctttggg attcttggct
     2821 ttattattgc ctttttattg aagaaaaaag aacctgttct aatgaaagcg ggggataatg
     2881 catgattatt ggagttttga ttgtcagctt gcttgctttt gctttaacga acgtgttcgc
     2941 taaaaaaaca tggcaaacct ttttatcttt gattttcgga ctaatcttcg tcgcttcact
     3001 aagtttgatc gtcgctaatt tgtccaatca ctttggaatg gaaaaagtaa cggaaacaaa
     3061 aacagaaaaa attgtttcca gtgctgattc ccaaggagca gatatgcttt tgtataaagc
     3121 tttagggaat ggaaaagaaa aagtgtatct ttaccgaaca aatgaaaaac aagaaaaacc
     3181 aaaagcaact ggtacggata acgaaacaaa taaagtagaa aagacagacg gcgatgctga
     3241 aaaagtgacg aaaactactt attgggaata caaaaacgac atgtataaat tctggttcaa
     3301 tattgctgat aacaatcacg aatatgacag ccgagtgaat acattcaaaa tcccagagac
     3361 atgggtagaa ttaagtacgg accaagcagc caagttagct gaattagtga agaaacagca
     3421 aagtacgatg gaaagtgaag caaaagctta tgttcaagac ggtatggtaa aagcaatgac
     3481 tgaaaatcca aaaatgagca aagcagagca agaacaacgt acgaaagcct tagctgctga
     3541 attccaacaa caagcattcg caaaattagt gaaagaagca aaaggcgaat aatattttga
     3601 acaccatgta ggaggttgtg aaaaagctgc tctgcatcaa gcagtaagaa caatcagata
     3661 aaaatagcac tccatatttt tcatctgatt gggcttagtg ccgtagatgc aagcttttga
     3721 acaccgttta aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt
     3781 tcaaaaaaca gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg
     3841 agaacaccgt ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt
     3901 tttttgctat gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc
     3961 ttttgaatca aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc
     4021 gtatgatata agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa
     4081 tgtgccgtat gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg
     4141 ctacatcctt ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat
     4201 tgtagcagtt acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct
     4261 cttgataaac ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg
     4321 tggaaaccca tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac
     4381 ctcttgataa acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata
     4441 tgagaagcta tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac
     4501 ctcttctttc ataatggttt ttcaccatct ttataataaa ctggttattt gatatggaaa
     4561 tctatttttt ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag
     4621 gcgttgattt gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt
     4681 cccggaacgg cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg
     4741 aaccgaccat cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta
     4801 gtgactgttc cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg
     4861 attactttaa cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct
     4921 ttttccatat taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc
     4981 caaaagtttc attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa
     5041 agcaggaatt ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa
     5101 gtgaatggca tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat
     5161 tgttacatca gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac
     5221 tgttttcata cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac
     5281 agcagcacct aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag
     5341 tgataagtcg gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt
     5401 ttctatcatc ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga
     5461 agcgccactt acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg
     5521 cactcctttt tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc
     5581 aatcttctac ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg
     5641 taccgtcaaa gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt
     5701 ctggtaattc tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt
     5761 tatctccttg gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa
     5821 catcttcatc gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag
     5881 ctgcttgacg ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca
     5941 tcaatttacc accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt
     6001 tatcgaccaa ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt
     6061 cactgggacc aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga
     6121 ctttcactac ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg
     6181 cttttcctga gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt
     6241 caatgatgaa ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt
     6301 gaataggttc gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg
     6361 taggtggttc gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga
     6421 taggcattgg tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc
     6481 caggcatgat gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta
     6541 catcgctcat tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac
     6601 cagcatcttc aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat
     6661 cggtagctag atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt
     6721 tgattggatt ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca
     6781 aaatttcacc tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga
     6841 aacctttgat attgttgaaa gtcatagctg gtccttcttg agtcggacgt tttactgtac
     6901 cgccagcacc gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat
     6961 ctgtttcgtg atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat
     7021 acggttgatc tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg
     7081 tgaaaaagag gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg
     7141 tttttttgat aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag
     7201 tgttggagga aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga
     7261 aaatatagcg aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc
     7321 tcattggaca gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag
     7381 aaaaaatctt ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc
     7441 agatggaaca gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa
     7501 aggaaagaaa agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg
     7561 aacatattac ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa
     7621 tctaaatgtg gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg
     7681 ctgccattcg tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta
     7741 gaataatcgc atggacagga tttagttgag caacattttt tagatccgtc atgttgtata
     7801 agatgctatt gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag
     7861 aaatacctaa aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac
     7921 ctaaagcttt tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga
     7981 tactgatcat gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag
     8041 tgatagcatc catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa
     8101 tgattttatc ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt
     8161 ctttgtcttc aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta
     8221 aataactaag caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta
     8281 caccactgtc tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag
     8341 tcgttaattg atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt
     8401 tcacgcgtag gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat
     8461 aatctgtatt agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta
     8521 ctaatttgaa tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat
     8581 caaatccaag attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca
     8641 cgacatctgt tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa
     8701 agttttcttt gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg
     8761 ctgacatcgt actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga
     8821 caggctgtac tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc
     8881 cgatattatt acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa
     8941 tcttattcgt gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt
     9001 ctggataatc cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta
     9061 ccttagaaat agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt
     9121 tttggaatcc agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag
     9181 caaaggaggt caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta
     9241 acgctgtcca aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt
     9301 cgatgtgagg atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg
     9361 cgtattgatg ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata
     9421 actcttggat caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt
     9481 catcgcacaa aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca
     9541 tttgtccacc agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt
     9601 gcaatgcatc ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc
     9661 caagttcaac gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga
     9721 aaccgataga gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact
     9781 ttccgttgat taccatatca ccggaatcat aattatctag tccaccaatc acattcagca
     9841 tagtcgtttt accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag
     9901 cgacagacac accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta
     9961 tatcttttaa ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata
    10021 agtatatcag aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa
    10081 gaaaaaatct agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt
    10141 agaagatgat ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc
    10201 agtcatcacc gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga
    10261 attaatcatt acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt
    10321 acgtagcacc agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga
    10381 taagaaacgc gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa
    10441 tgagatgatc ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag
    10501 cttgataatc ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca
    10561 ttcgttgatt ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa
    10621 caagatcttc actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga
    10681 agaacgaacg atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga
    10741 ttttcaaatc atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa
    10801 aagctatttt cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg
    10861 acactgctgt gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct
    10921 gaatcggctg gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc
    10981 gtgggtacag gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta
    11041 gggacaaata tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag
    11101 aaagtagcag aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat
    11161 agtatcgaga cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca
    11221 ctagcaacaa tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa
    11281 cgccaaatat ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag
    11341 aacatcttaa aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat
    11401 cgattagatg aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa
    11461 cagctagaat tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg
    11521 taccaagtgt ggctgaatat catggataac gccataaagt acaatcaaat caatggacag
    11581 attcatatca aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt
    11641 gtaggaatga atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca
    11701 agtcgtcaaa tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg
    11761 catgatggac gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg
    11821 ttaagtaaac aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg
    11881 gtttttagtc gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat
    11941 cgctgctttc ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat
    12001 gcaagaaaga gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga
    12061 aaatgtaggg cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa
    12121 gaatgctcac cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg
    12181 agaatcacag tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc
    12241 cccatgtcat ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt
    12301 tttggttcaa atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg
    12361 gggccaagga gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta
    12421 gctaaaggat gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac
    12481 tcaatcgaac ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca
    12541 ttggcgtcat tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca
    12601 ggatggcgtt tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt
    12661 atcgttaaga tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc
    12721 atagcatggt attgttctac gacatttttt acatatggga gcaataagct tccagcttcg
    12781 gtcaattcga tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac
    12841 gaaagaatct gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg
    12901 aaattcattg tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc
    12961 ctcctactta ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc
    13021 tgtctgttac aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt
    13081 tcgcttcgta gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg
    13141 ttccgttttg tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt
    13201 taaagcacag ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat
    13261 tgcgccgatg aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg
    13321 tttgattgtt catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat
    13381 ttctaaaatc ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt
    13441 agtgacggtc attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc
    13501 tgggatgaca ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc
    13561 agctattttt gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat
    13621 tattttttat attttgttct tattggcaaa atttatttat ccattgacta caccagacat
    13681 gatcttagat tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat
    13741 caacgtgaaa atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact
    13801 gagctggatg tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca
    13861 ttttttgctg actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg
    13921 attttgaaac tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga
    13981 atagaaggtg acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta
    14041 gcagcattaa gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt
    14101 ctctctgtca gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat
    14161 cttgagacct atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca
    14221 atgggaagtc gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta
    14281 gaccggttat tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct
    14341 tcaagaaatt cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt
    14401 agattctgga aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc
    14461 cttaaaatta aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa
    14521 aaatccaaaa agacaaattc gcctgatttg gttaatcatt atcggtttat ttgcttctcc
    14581 tgtcctcatt ccactagcac tggggtttat attggttatt gggggactat tggttgcttt
    14641 actagcgctc atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt
    14701 catgatcatc tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat
    14761 cggtgtcggt ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg
    14821 aacaaaaggg cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat
    14881 tacaaaaaga gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa
    14941 acattttttg attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac
    15001 ttatacatta ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat
    15061 ggttactgag acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca
    15121 aacagtttcg gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga
    15181 aaagccagaa ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac
    15241 aggtgcaatc attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga
    15301 tcatgaatta tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt
    15361 atcaatcaaa aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac
    15421 aggaggaaca ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt
    15481 ggataacttg atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag
    15541 caaagaagga aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag
    15601 tggctatact atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac
    15661 aaatactttg ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat
    15721 caatattacg acggatcaag aggacaatga aacagattga tcctgtactc aactggatat
    15781 tttaagaaaa aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca
    15841 taactatagt aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg
    15901 aaggtagaag aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat
    15961 atcactcaac taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac
    16021 ccgaacaatt cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta
    16081 ttgacggtga agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg
    16141 aagtatgatg ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt
    16201 tcagcaggga tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg
    16261 gttcgaacaa aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg
    16321 tacatcactg aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa
    16381 aattaaaaaa gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga
    16441 gagaaaaaag agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag
    16501 ctttagttgg attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt
    16561 ttttaagtat ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca
    16621 gtcctaatca agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa
    16681 atggcttttt ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga
    16741 atttcaatag ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag
    16801 cagtagtagt ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc
    16861 aagattttgt agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt
    16921 atgatacatt caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg
    16981 agttgcaaaa agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac
    17041 gcttgaacca tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag
    17101 caaaagccat tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa
    17161 tggccttaga gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc
    17221 aattgatcaa taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca
    17281 atacaggcga catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt
    17341 taggacggat tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg
    17401 aaagaagaat gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata
    17461 taaagtaaga gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc
    17521 gttgtggtac ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac
    17581 tatgtacaaa ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa
    17641 acagtcaact atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg
    17701 gacttcaagg gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg
    17761 aacaaaaata aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca
    17821 gcactggaaa aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga
    17881 atgtaacaaa agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca
    17941 gcttcgatgt agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt
    18001 cgacactttt gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca
    18061 atcaaaaaga tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga
    18121 ttggctttat tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg
    18181 ctgttcctct ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa
    18241 ttgcagaacg tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg
    18301 gacaaaaaca acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag
    18361 gggatgagcc tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg
    18421 acgaattgaa tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg
    18481 caagttattg ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac
    18541 gtggagatca aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg
    18601 aacagtaggg ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt
    18661 ttaagagact acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg
    18721 tttgaatcaa tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca
    18781 gttatcattt tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta
    18841 tatgcaaatt cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg
    18901 ggagcaaaag gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc
    18961 gcagctactt tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta
    19021 ttagtggatc agttagatct caatatttcg cattttacac cttttagtat tcacgggttg
    19081 ttgatcactg ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt
    19141 tcgattgtca aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc
    19201 aagcagcata aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc
    19261 ggttactata tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta
    19321 gttacgatcg tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca
    19381 ttactaaaga aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag
    19441 ttaaactttc gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc
    19501 ttggcactgg gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca
    19561 gaaaacaatt ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa
    19621 atcaaagaac tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg
    19681 atttactata atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat
    19741 ggaacaccgc cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact
    19801 gtacaagagg aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta
    19861 gtcagtcaat cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag
    19921 gtaaaagact tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg
    19981 aacaatccat ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg
    20041 tataatggtc tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg
    20101 accatgcttg ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct
    20161 cgttatgaaa tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt
    20221 agagaagtag gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc
    20281 ggattacaaa tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt
    20341 acgatattct tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga
    20401 atcgtattga aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa
    20461 gcaaaaatag ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt
    20521 tgaacaccgt ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc
    20581 acggtctttt attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag
    20641 aaaacggttt ccatgtatac tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac
    20701 atggaaatca atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa
    20761 aatgggacat ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata
    20821 atcgataatg aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa
    20881 aaagaccctt atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca
    20941 ttcaaattag atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta
    21001 catggtggtg cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa
    21061 aacgaagcat cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga
    21121 actttagatg tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc
    21181 caagggatca gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta
    21241 accggtgatc cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt
    21301 gctacgctca ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca
    21361 tttgacttcc aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca
    21421 atgatagtgg gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat
    21481 gctgcggaat tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca
    21541 ggaatcgtga tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa
    21601 ttagtaaatc atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt
    21661 gaaagttttg gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac
    21721 aaaataaata taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct
    21781 ttttaattta ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa
    21841 caaggttagt acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg
    21901 tcttgccgta aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc
    21961 gttgttgacg cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt
    22021 ccatttgatt ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc
    22081 agttgttgct gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat
    22141 cgcgttcaat ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt
    22201 tgcttctttg tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc
    22261 agtcagtcca tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata
    22321 tttacggaat tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt
    22381 gaaggtcacg ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc
    22441 gcttgataat aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga
    22501 tgcgtagatt ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa
    22561 ctgatcagtt gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga
    22621 tgagccgcct gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc
    22681 aaaatcaggc gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc
    22741 atggataaat tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg
    22801 tccccagaag acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata
    22861 ttgctgttcg cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata
    22921 agtcaaacca gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc
    22981 aagatgcttg aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa
    23041 tacagcatca attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat
    23101 accgctttga tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga
    23161 accattgttt ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg
    23221 gtttgtttga ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt
    23281 tgaaccatta ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg
    23341 tgtactaggg acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc
    23401 tttaaattct gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata
    23461 atttacttct ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt
    23521 aatagtgtaa gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat
    23581 atccaaaggt tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat
    23641 caaagaagga gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc
    23701 agccggatca atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg
    23761 gtcttctgta aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt
    23821 tgtgactgtt tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac
    23881 agacggagca atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat
    23941 aaactagtcc ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt
    24001 tggaacagat aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa
    24061 ataaaacaat ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta
    24121 ttgcatagac cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg
    24181 taaattatac caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa
    24241 gaaaaagact gaaatatgtg ataaacatct catacttcag tctttttcat taactattca
    24301 taagacatta ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga
    24361 ctaacagcca gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg
    24421 gtcagactac caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca
    24481 ccagcagctg caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg
    24541 taaacagttg gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc
    24601 gaacgggttt ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca
    24661 aaattggctg ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg
    24721 atcatgacag ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca
    24781 gcgatgattg cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct
    24841 aaaccttcgc caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg
    24901 ataactaatg aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg
    24961 aggaattttt caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac
    25021 gtatactgca tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct
    25081 gaaagtaaag aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat
    25141 ccattcactt taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag
    25201 acggcattcg acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca
    25261 atcgtagtcg ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg
    25321 atcggcgtaa agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct
    25381 ttcggagctg aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga
    25441 tccatgatta tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc
    25501 tgttttaatt tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc
    25561 gcacatggaa ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga
    25621 atctgctcgg acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc
    25681 cactcactaa tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac
    25741 agttattcaa ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta
    25801 acaataattt gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt
    25861 caatcgattg tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa
    25921 gaccgtttga gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat
    25981 ccccgatact taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat
    26041 tgattacttt tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg
    26101 attgttctaa agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa
    26161 cagaagaggc tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa
    26221 gtgtgctgct taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca
    26281 ctttaaaagc agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc
    26341 ctagtgtaat gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca
    26401 aactgttatg atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta
    26461 taatgatatc tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat
    26521 tcaggatcgt tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta
    26581 agctactttc aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta
    26641 ggacttcttg ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc
    26701 ctgctgcgtc taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc
    26761 cagatgtatc gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag
    26821 ccccaacgcc tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt
    26881 tggcaccttt acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct
    26941 tgggcatgtt ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg
    27001 tgttcatttt acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa
    27061 acgttttagt aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt
    27121 caagggtgca gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc
    27181 tttttctggg aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa
    27241 gattggttgt gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc
    27301 atagccaata atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata
    27361 taatccaaaa gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag
    27421 ttctgctgtg atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg
    27481 gtcgtgaggg atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac
    27541 attttccggt ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa
    27601 gtgcatgccc gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc
    27661 ttcagatttt ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt
    27721 gattgcatct gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt
    27781 gagctcggct agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt
    27841 gacgaaattc tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg
    27901 attcgtgata tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct
    27961 agcaaaatag tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt
    28021 tttcggactg aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac
    28081 gccggaaagt ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct
    28141 atctaaatcc tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt
    28201 gccagtactt atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt
    28261 gcagttttcg gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg
    28321 caagcatctt cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca
    28381 tatacaccgt ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga
    28441 agttgaagat caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac
    28501 atattatctg tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca
    28561 gaagcagtca ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct
    28621 acgttcacta aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg
    28681 tttgtcagaa tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt
    28741 tgcatgtcga tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa
    28801 tcattcatga tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc
    28861 gtttatttgt caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa
    28921 aataaataag tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa
    28981 tggaggaatc agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg
    29041 agaaacgacc attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt
    29101 gattatactt ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat
    29161 ggatacacct gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga
    29221 taaacagctt actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct
    29281 cgttcctaat ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc
    29341 gcttgatcct gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc
    29401 gtcccaatta tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa
    29461 tcccaaactt cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca
    29521 agtattgaaa ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac
    29581 acataattct gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt
    29641 aaggtctgtt gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga
    29701 ttttatgaaa acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg
    29761 acgattcatt gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa
    29821 aactgctgga cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc
    29881 tgatttgcaa atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa
    29941 gatcccagat gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa
    30001 cgaagtgatt caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac
    30061 tgatggaaaa ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga
    30121 agggtataaa atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta
    30181 taccatcacg ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc
    30241 gaacgtcgga aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac
    30301 agatatttat tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag
    30361 caaagcttac aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga
    30421 tcgacccgaa gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc
    30481 acagcaaaaa atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga
    30541 tgctaaaaaa cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg
    30601 aacaatcgct gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca
    30661 attagttgag aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga
    30721 aaaaattgaa aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg
    30781 ttttcaagaa tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt
    30841 tttctttttc tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga
    30901 aaaccgcagg gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa
    30961 aaaatatgca atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt
    31021 aggaacgaat cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg
    31081 gagtgcgctt attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat
    31141 tgccgcattt ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc
    31201 attgcttcaa ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc
    31261 gctgtggtca cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa
    31321 gtcaagaatg cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg
    31381 cgtgggattg aaagattctc taagttctgt ttcagccaaa caatttggac cgatcattga
    31441 ctatcaagca atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga
    31501 tatgctgcag aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga
    31561 attgagaaaa aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc
    31621 tgatttggat cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa
    31681 aacaggaatc gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca
    31741 tatttcgctt tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa
    31801 aaactatcta ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca
    31861 atcgatgatg gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga
    31921 aatgctttcc gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa
    31981 acaaatcgaa acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt
    32041 cgtattatca ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc
    32101 cgagcgtgta cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac
    32161 gatgtacatt gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg
    32221 tgtaggatat atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt
    32281 tccattagtg atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac
    32341 ggttattgtg atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt
    32401 gaaatcgaat gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga
    32461 aacaaacggc aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag
    32521 ctgattgaac accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa
    32581 tactcaaata aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa
    32641 aagcttttga acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga
    32701 tagacaaata catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat
    32761 aaagataaat tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat
    32821 ataagttgtg gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga
    32881 caaagtcatt taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg
    32941 agatttaaaa ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat
    33001 ttggctaaac cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta
    33061 cacagccatc gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc
    33121 aaagaaatac cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca
    33181 tgaatggttc aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag
    33241 agaagagcca acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga
    33301 tacggggaaa tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa
    33361 ccaagcagta agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa
    33421 aggattccgt ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa
    33481 agaaaatgat ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga
    33541 attgaaccaa gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc
    33601 tacgacgatc gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt
    33661 ctttaatttc catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc
    33721 atttgatttt gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg
    33781 taacggctgg aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt
    33841 tgtagctatc gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt
    33901 gaaccgtggg acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta
    33961 ttcatcgatt tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga
    34021 acaaggattc acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc
    34081 tcgaacaccc atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg
    34141 gttaaaagtt ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga
    34201 ttctattttg tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc
    34261 acaaggagat tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca
    34321 atttgaagga cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc
    34381 catcccagaa ggattcacag aagccaatat tcttatcgat aattattccg atactgttct
    34441 tcatcaaagt ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa
    34501 aaacacaaaa cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt
    34561 aaaataatct tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt
    34621 attgtagcgt tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata
    34681 gataggaata ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac
    34741 gattaagatc gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa
    34801 gtcaccgtgg agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt
    34861 agagtcttgg aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg
    34921 aatgatacat aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag
    34981 taagaaacaa acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag
    35041 aaatgaaccc aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc
    35101 tggtgggaca atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa
    35161 agcgacaatt ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt
    35221 gctgatccgt tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt
    35281 cacgtcgtca atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa
    35341 aaattgtcgg agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt
    35401 ctttgcctgt tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa
    35461 aataatcaca taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt
    35521 gatgactggt tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt
    35581 agcgataatg attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat
    35641 cagcgcaagt aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg
    35701 gatcaaacga ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac
    35761 ttcattatag acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc
    35821 gtcaatcatt catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt
    35881 taaccatatg ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc
    35941 gaatcggaac attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga
    36001 taggtatatt ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga
    36061 aagccgagga cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt
    36121 ttacaaaagc aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg
    36181 attcccacga ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct
    36241 ttgtttataa tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag
    36301 aaggcaatgt ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag
    36361 aaggacatga tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac
    36421 atgtatggct agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga
    36481 ttgaagctta cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga
    36541 aacttcaagc actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt
    36601 ttgtcacgca acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat
    36661 cgattgctgg tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac
    36721 actttgttaa agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta
    36781 ttgccagaac gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag
    36841 gattgacgaa tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc
    36901 tcgaagcgtt gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca
    36961 aaaaagaaaa gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc
    37021 tttcagattg ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg
    37081 atcctgtttt tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag
    37141 aatattatac gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga
    37201 tggcatttac gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag
    37261 aaatcttgac ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata
    37321 aggaaagtgg cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact
    37381 ccgaacattt tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg
    37441 agaattggcc aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc
    37501 ttttgcactg ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt
    37561 ccaaactatt cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga
    37621 tggtctcgcc gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt
    37681 gtgtattgat aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt
    37741 ctttgatctt ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg
    37801 gcgctcctag cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat
    37861 cattaaactc tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa
    37921 ttttgctcag gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat
    37981 aatcagtcgg ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca
    38041 catagattat ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat
    38101 ccatttcact gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga
    38161 tcttggctgc attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta
    38221 agttttcaat catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat
    38281 cgtcttcaca aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa
    38341 tcgtttgaga aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct
    38401 ttgtcaattc atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg
    38461 agaacccttt ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac
    38521 gaatcatcac ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag
    38581 cactagctcc ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg
    38641 tatgtttcgt atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt
    38701 cctgtgccat catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat
    38761 ccaacatact tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt
    38821 gatcataata agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa
    38881 aaagcagatt ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat
    38941 ctttgatata atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct
    39001 tattagagat tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga
    39061 aaaaactcgt attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa
    39121 taatgatata gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca
    39181 cagtgtgaaa ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa
    39241 aagcggataa gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt
    39301 tcaaaacaaa aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc
    39361 caaaaggaag cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca
    39421 tcagcattcc tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa
    39481 tcaaaataca agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt
    39541 caatcaataa gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca
    39601 taaagtacag ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt
    39661 aatttttcag ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag
    39721 tcagataagt tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt
    39781 catcaagtag tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa
    39841 ataggtagaa aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat
    39901 gctgatcgcc ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt
    39961 acctcttgat ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat
    40021 tgggaaggag atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag
    40081 tagtgtccac agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg
    40141 gatgcagata taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga
    40201 aaagactaga acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt
    40261 tacttggaca tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa
    40321 tttgttcaca actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa
    40381 aaaataaaaa acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc
    40441 tcctaaaaaa atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga
    40501 aaagtacttt ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga
    40561 ccttataaaa ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga
    40621 aacatatgca tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat
    40681 ctatgaaaat agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc
    40741 tcataatctg cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca
    40801 gataaaatgt tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg
    40861 aataatgtta aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg
    40921 gcaggagaat actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta
    40981 ttttcatgaa taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat
    41041 aaagtcaagg cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca
    41101 ggaaggatgc cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca
    41161 ctaactgaaa tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat
    41221 aatgaagtat tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt
    41281 ttctttttga acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta
    41341 ctagaccgct ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt
    41401 gtttctgaag tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta
    41461 gaagaaattt cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa
    41521 actatgttag cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct
    41581 gaactctatt cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt
    41641 gatatatgtc ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca
    41701 tgtggagaac aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca
    41761 gatgcccagt cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact
    41821 aaataatata aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct
    41881 tgcttagttt ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc
    41941 cataaatgaa atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc
    42001 gaatgggcgc caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca
    42061 agaacgacac ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa
    42121 taatcatata agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag
    42181 gcacgcccgt tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa
    42241 atcgttacta atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact
    42301 gcttcataat atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca
    42361 attagatact ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta
    42421 ccaacactta gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt
    42481 tgagcagagg caaaagcacc atattggata taagtataac tgtccatggc tcctccgata
    42541 aatgtcagca aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc
    42601 accttttatg aatatttttg tcttccttat cttagcataa acgattgaaa aaaaaggaaa
    42661 aattttcaga aaactaaaat catatcgctt cccattttca tttttagaaa ggtctgttag
    42721 tataaagaaa aaatagacaa cgaaacttta aataaccaac ttgaaataaa caaattcaaa
    42781 gaagaaagat gggaaggaaa tcaatcagtt gaatgaaaaa gaaattctcc gattacaaaa
    42841 agaattgaaa cgctgggaga acaagtataa aaagcttcaa caagtctttc ggctacaaga
    42901 agaaatcatt gctacctatg aagcggctta tggcgaagca cccggactta ttgaggaaga
    42961 agtacaagta aaagaaagtg aaggaaacag ctctttcttt aaaatgatgg agaaacgttc
    43021 ctataatcgc ttcaatcaag aacaaaaagc agctatcaca tatgatatga agaaacatct
    43081 tcgaatcata gcaggagctg ggagcggcaa aacgcaaaca atctgtgcaa aagctgttta
    43141 tctgatgacg caaaaacaag tagacgaaga acgcatacta atgatcactt ttacaaggaa
    43201 cgctgcaaat gaactaaaaa aacgagtaga taatttcagc cagagaaaaa ccgctgtcca
    43261 tatcggaaca ttccatagta tcttttttag gatatacaat gaaatttgtc gaaaatttcc
    43321 tgaagtagca atgcaaggaa tacaaggaga cttttcaaag gatactgcac aaaaagtgaa
    43381 tgctgttttg caacagctga tacgtaaata taatctttat atatttgatc aatatggaga
    43441 aaaaacgatt gcttctcggt tagactattg gcagaatatg aacctttcag tagaagaaat
    43501 ggttcagtta gttaaagaaa aatatgattc cattgataag aatgcacgac agccgatatc
    43561 agaacgactg tatggattgc tcacggaact ccaagaacaa aaaagaagcc agcaattgct
    43621 agagttcaat gatgtactcc aaaatctgaa aagcgctttg gagaatgagg agatccagca
    43681 ttatatcggc caaaaatatg attatctatt cattgatgaa tttcaagata ctaatccact
    43741 tcaatgggaa atcgtgaaac ggatgacaaa ggaaaacagg atcaagttga ttgttgttgg
    43801 agatgatgat cagagtatct atggattcag aggatcagag ccagcataca tcaagaactt
    43861 tgaaaaagaa tatcctacca aaactctttt cttattaact aattatcgtt ctcgggcagc
    43921 tattgtccaa ggagcaaata gattgatcag ctataataaa aatgatcgga taccaaaggc
    43981 gatgattcca gcacaaaaag aagcaggtgt tatggaagcc tatttgtttt ctgatactaa
    44041 agcagaaagt cagtggctaa tcaaacaaat tcagacattt attcaaaaaa atgggaaata
    44101 taaggaatca atcatattat accgatcagc ttcacaaacg cagcagcttg tccaatctct
    44161 gctgaaaacg aatattcctt ttgtactgga agcagatagt ccatatgaag gtatctttgg
    44221 tatcaagtct ttccaacatt tctatcaaaa aattgttcat tggcaaacag cactgaatct
    44281 gcaaaagaaa aatcaggcct accagcaatt gctccggcag ctgatggcag actgctacct
    44341 gaaaaaaagt gaatgcgatc aatacttttc tcctaaatat caaaatatag ccgttgcaga
    44401 ttatattttg tcgataagcc ccaatttaaa atcgaaatct gcagaaatcc gagagtttga
    44461 ggaagcgttg cgtaaaacag accagcatca agaaatctat tcgcttgttc aaagctatct
    44521 tcatctgcca cgtatagcta aggaaatcga ccagagtgat caagaatgga tacgagaaga
    44581 agtaaagcag catgctactt tcagaagact ccaagcctta tcgcaagaaa cccaagcgac
    44641 agctaaagaa ttaaaaaccc gcttgattgc ttacagacaa ggaaaacttg atgcactatg
    44701 tatccagagc attcacaaaa gtaaaggtct tagttaccga aatgtctttt tgattggttg
    44761 taacgaagga agtttgcctt ataacggagc gacagaaaag aaagtaatcg actttaatga
    44821 aataaaagca gaaccagtaa cgacgataga agaagaacga agactatttt atgttgcgat
    44881 gactagagca agaaatcgtc tgtatctatg tgtacctcaa atgaaaaatt caagaaaatt
    44941 gaaagtatcg agatttatca aagaaaccgg gagtcgtgtg aaaaaaggaa agtgatagaa
    45001 gagagggtgt gacagaagtg gtcagtttca agaaagaaga aggaatgtac gaaaattgct
    45061 tctcaaattt ttgtgaaatt tcagcttatt ttcgaagaag ctatttctgg aacacagttt
    45121 attcggaaaa gggaggtgtg acaagaattt tgtcacacct cccttattta ttttgaaaat
    45181 gagaatacta ttatcaaaat agagaatata tagaaaaatt ctcattattc aaacgtaaat
    45241 aatcagttat tttgattttt tttatatttt attagctaat aattggtatt ttaaaagaaa
    45301 ttactgtaga attggattat aattaaaaag gagtgagaaa atgataaaag tatatacttc
    45361 gcctagctgt acttcctgta gaaaagcaag agcatggttg caagcgaatc aacttgaatt
    45421 tgaagagaag aatatttttg ccgaaccgtt aacagaaagt gagatcaaaa agatcttggc
    45481 agcgactgaa ggaggagttc aagatattat ttccactcgg tcgaaaattt acgaaaagct
    45541 gggcatagat tttaacgaat taactttaaa gcaaatgatc gtcttattca aagaatatcc
    45601 ttcattattg agacgaccta ttttgattga tgaaaaaaga atactaatcg gatttaatga
    45661 agatgagatc cggtcatttg tccctcgtga aattcgatgt gttgccagaa atctgatcta
    45721 tttacaaaac aataacatct taaattcata gggagggagc cttcgtggaa gtgaaagtct
    45781 atggatcagc gcactgtgta acaagtctga aggcgaaaca atggttagaa caccatcaat
    45841 tgccttatca atttgttgac ttagaagaac gcgatttaag tacagaagaa gcagaagaat
    45901 tatgcagttt tgaagaagtg caagcagaac agctatttgc gacttggtct gaggcttttc
    45961 acaacattgc gattgacctt tcctgtgtag gaaaaaaaca actgattttt ttatgcacac
    46021 aacataccaa tctcctcaga cgtcctttga ttattatcga tgaagttcta tttattggat
    46081 acaatgagca gttgatggaa cagcttatct taaataaata gactttaact gttttaatca
    46141 agtcactgag catttcatac agttgtaaca gtcgaacact tagcatcaag cgtgttatgt
    46201 gttctttttt tgactttatt tttctactat agagacatgc tcaatttatg tggtcaaaat
    46261 tcaaatctag gtggggatat agagttaaaa atatattgac atgtgtaaat ttacatgata
    46321 tattcatttc tgttgtttta agtagcaaag caataaaata gtattttaaa aaacatataa
    46381 aatagttgtt gacatgttag aaatgacatg ataagataac tgagttgtta aaaaagaacc
    46441 acttgtgaag cttgattcta tcgaaaaaaa cttcaaaaaa gttcttgata aataacaaat
    46501 gataagttat gataaatgag ttgctgtaag atttcgaaaa acgaaatcaa aaaaactttt
    46561 aaaaaagagt tgacaattac ttgtctctct gatatgatat aaaagttgct acggcagcca
    46621 aaaacgaatc ggggaacact cctgatgaag tagacctttg aaaactgaac aaagtaagac
    46681 aaaccaaatg tgtagggcgt cttgattcaa ttcaagacaa caaaca
//
LOCUS       DAMEEU010000014        44849 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.014, whole genome shotgun sequence.
ACCESSION   DAMEEU010000014 DAMEEU010000000
VERSION     DAMEEU010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44849
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.014"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            212..604
                     /locus_tag="PB779_000811"
     CDS             212..604
                     /locus_tag="PB779_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDE0738353.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="PB779_000812"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="PB779_000812"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HDE0738354.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="PB779_000813"
     CDS             3165..4775
                     /locus_tag="PB779_000813"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HDE0738355.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="PB779_000814"
     CDS             5067..5936
                     /locus_tag="PB779_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HDE0738356.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="PB779_000815"
     CDS             6101..7372
                     /locus_tag="PB779_000815"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDE0738357.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="PB779_000816"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="PB779_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HDE0738358.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="PB779_000817"
     CDS             8763..9026
                     /locus_tag="PB779_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HDE0738359.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="PB779_000818"
     CDS             9471..9920
                     /locus_tag="PB779_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0738360.1"
                     /translation="MRFDQLIAEELIVFDPSIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="PB779_000819"
     CDS             9977..11395
                     /locus_tag="PB779_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0738361.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="PB779_000820"
     CDS             11395..12255
                     /locus_tag="PB779_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HDE0738362.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="PB779_000821"
     CDS             12429..13202
                     /locus_tag="PB779_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDE0738363.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="PB779_000822"
     CDS             13349..13714
                     /locus_tag="PB779_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HDE0738364.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="PB779_000823"
     CDS             complement(13862..15070)
                     /locus_tag="PB779_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0738365.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="PB779_000824"
     CDS             complement(15089..15367)
                     /locus_tag="PB779_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738366.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="PB779_000825"
     CDS             15521..16216
                     /locus_tag="PB779_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDE0738367.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="PB779_000826"
     CDS             complement(16658..17455)
                     /locus_tag="PB779_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HDE0738368.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="PB779_000827"
     CDS             complement(17452..18636)
                     /locus_tag="PB779_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HDE0738369.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="PB779_000828"
     CDS             complement(18661..19908)
                     /locus_tag="PB779_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HDE0738370.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="PB779_000829"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="PB779_000829"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HDE0738371.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="PB779_000830"
     CDS             21888..22202
                     /locus_tag="PB779_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HDE0738372.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="PB779_000831"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="PB779_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HDE0738373.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="PB779_000832"
     CDS             22887..23531
                     /locus_tag="PB779_000832"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HDE0738374.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="PB779_000833"
     CDS             23546..23875
                     /locus_tag="PB779_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HDE0738375.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="PB779_000834"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="PB779_000834"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HDE0738376.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="PB779_000835"
     CDS             24863..25687
                     /locus_tag="PB779_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HDE0738377.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="PB779_000836"
     CDS             25680..26027
                     /locus_tag="PB779_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HDE0738378.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="PB779_000837"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="PB779_000837"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HDE0738379.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="PB779_000838"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="PB779_000838"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HDE0738380.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="PB779_000839"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="PB779_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HDE0738381.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="PB779_000840"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="PB779_000840"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HDE0738382.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="PB779_000841"
     CDS             31657..32451
                     /locus_tag="PB779_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738383.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="PB779_000842"
     CDS             32441..34483
                     /locus_tag="PB779_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738384.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="PB779_000843"
     CDS             34764..34913
                     /locus_tag="PB779_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HDE0738385.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="PB779_000844"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="PB779_000844"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HDE0738386.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="PB779_000845"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="PB779_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HDE0738387.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="PB779_000846"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="PB779_000846"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HDE0738388.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWCTPNKIIQQATALKG"
     gene            37921..39189
                     /gene="dltD"
                     /locus_tag="PB779_000847"
     CDS             37921..39189
                     /gene="dltD"
                     /locus_tag="PB779_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HDE0738389.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQLK"
     gene            39330..40412
                     /locus_tag="PB779_000848"
     CDS             39330..40412
                     /locus_tag="PB779_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HDE0738390.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            40412..41215
                     /locus_tag="PB779_000849"
     CDS             40412..41215
                     /locus_tag="PB779_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HDE0738391.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            41285..42025
                     /locus_tag="PB779_000850"
     CDS             41285..42025
                     /locus_tag="PB779_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDE0738392.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            42036..43040
                     /locus_tag="PB779_000851"
     CDS             42036..43040
                     /locus_tag="PB779_000851"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HDE0738393.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(43085..44782)
                     /locus_tag="PB779_000852"
     CDS             complement(43085..44782)
                     /locus_tag="PB779_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738394.1"
                     /translation="MKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLE
                     KPLDEANLLIKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTL
                     TVSSPYQNYAGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMY
                     KQKRLEYSLILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYY
                     WSRMFYYKKWYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLAC
                     IGEAYKNNRFYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISY
                     NLIDHILNTDKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLM
                     HTDQTKAKNYVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLP
                     EELPINDDDLAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYD
                     TNLFSRGITEELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT        14415 a         7827 c         9340 g        13267 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcacgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatc gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtag ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcgaaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg tgcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 ttaaaataaa gaaaacaggc gagtgttgct cgcttgtttt ctttattttt gaatattctg
    39241 aataaaagat aaaaatacca agtttgcctg aacaaaaatc ataagcaatg gtataatcac
    39301 aatatgaata tagaaatggg ggaaaacatt tggatacaaa agaagaacag ctacttattg
    39361 atttaacttc tgcaaaagga gtacctggaa atgaagaaga ggtaagagaa gtattcagag
    39421 aatatgccaa accattcgct gatgatattt tttatgacgg tttaggcagt gtgattgcca
    39481 aacatggtgc tggcggaggc cccaaggtct ttatttctgg acatatggac gaagttggtt
    39541 ttatggtaac aaaaataacc gaaaaaggat tcttggaatt ccaaactctt ggaggttggt
    39601 gggggcaagt catgcttgct cagcaagttg aaatcaaaac acgtgaaggg aaaatcgtcc
    39661 acggtgtgat tggttccaaa ccaccacatg ttttaacacc tcaagtaaga aataaacctt
    39721 atgaaataaa ggatatgttc attgatattg gcgcatcaag ccaagaagaa gccaaagagt
    39781 ggggcatacg tcctggagat atggtcactc catatattga atacaaacga atgaatggca
    39841 gtaaatattt actggcaaaa gcatgggata atcgtatcgg gacagctgtt tctctgcgag
    39901 tattagagaa tctatctaaa gaagcacacc caaatgtttt attcgcagga agcgatgtgc
    39961 aagaagaagt aggcttgcga ggtgctcgaa caagtacaca ccttgtaaat cccgatattg
    40021 cttttgcttt agatactggt acagcaggag acactccagg aatgacacca aaagaagcag
    40081 attcgatttt aggaaaaggc ccacagattt tgatttttga tgcatctatg atcccgcata
    40141 aaaaattatt gaattttgtt attgatgtag cagaggaaat ggatattcca ttccaatata
    40201 cagtgatttc tggcggagga actgatgcag gacaaatgca tttgacaaga gatggtgttc
    40261 cgtctgtagc cattaccgtt cctgttcgtt atctgcattc ccatacatca gtgattcatg
    40321 aagatgatta tttgaataca gtgaaactag tcacagaatt agtgaaacgg cttgatagtg
    40381 aaacagttga aaaaattcgg agttatgaat aatgaataat agaataccta tttctgaata
    40441 tcggaaaaaa gcacgagttt ctttggaaaa tcaatgggga atcaatactt ggcttgtttt
    40501 cttatctata atatttacga gcgtcatcca gaactttttt gacggtttca gtccttttcc
    40561 ggaagaaagc atgcagcagc acttattgag ttttctagtc gataatttac ttttattcgc
    40621 attcaactat gcattgtttt acattgcgct agtagttgta cggggtggca gaccaaaaag
    40681 taacctttta ttttcagttt tccaaagaaa gtattttggt tcgatacttg gcatcaattt
    40741 gatcaattca gtcatcaact ggctactcaa cagtttaatc tttctgccca tgtttttaat
    40801 cagcggagtg agtacttata tgcagctgct tttcagttca aatgcggtac ctacgggtgt
    40861 catgccagaa gattttcttg atatcagctt tgttttatcg atgataggga tgatttttgt
    40921 ttcagcactc atcatgagta ttgttggcgg tttattccaa tttgctgcat ggacaaagtt
    40981 cgactatcct gatttgtcgg ttattcaatg tttgaaatat ggctggtttt tattgaaaga
    41041 tagaattggt acgtatattt tgttgcagct gtcttttatc ggctggtatt tgctaggagc
    41101 aatcgctttg ttcatcggtc ttttgtgggt cattgtttat gtgaatgtgt cagttgcaga
    41161 attttatgaa caagcacgga ttgaaaaagg aggtccagac gcctatttta cttagcatgt
    41221 aagcagttta ttcatcaaaa aaataacttt tgtggtagga taaatctttg agggggaatg
    41281 tacgatgaaa ttaactgttt taggatgctt aggagcgtat ccttataaaa atcaagggac
    41341 aacaggttat ttgcttcaat ctgacgggtt caatttgttg atcgatgcag gtagtgctac
    41401 gctgatcaaa ttacaagaac accttgatcc acttgatcta gatgctgtga tccttagcca
    41461 ttatcatcat gatcatattg ctgaccttgg tgtattacag tattactggc aacttcatcc
    41521 taagagaaat ccggagacat tgctttcaat ttatggacac acaaaagatt ccattcactt
    41581 tgaagaattg acgttggaaa atgtctcaaa aggacatcct tattttgaag ctgaagaatt
    41641 aaaaattggt ccttttctga ttacttttat ggaaacaatc catccagtag tatgttacgc
    41701 catgcgtatc gtagaagaaa caacggggaa agtattcgta tttacaggtg attcaggtta
    41761 tttggaaagt ttcgctgatt ttgcgaaaga tgctgatttg tttctagcag atacctatct
    41821 ttttgaagga aatgaacatc atcatgccca tttcacttca aaagaagctg gagaacttgc
    41881 gaaatcagct aacgtaaaga aacttgtact tacacaccta cctcagtttg gtgatttaga
    41941 acaattgaaa aatgaagcgc aaaaggcagc aggcaaaggg attgatatag aacttgctgc
    42001 agttgacaaa gtgtttaaca tttaggagga agaacatgat ttttgtacca aatgaaaacc
    42061 acgacccaag aatcaattta gcaattgaac aatatttgct gcaagaaatg cctttagatg
    42121 aacctatttt gctcttttat atcaatgaac cttcaatcat catcggcaga aaccaaaata
    42181 cgcttgaaga aatcaatcga gattatgtgg aagaaaatgg cattcatgtt gtccgtcgct
    42241 taagtggagg cggagctgtc taccatgatt ttggaaacct gaactttagt tttatcatgc
    42301 ctgatgatgg ggattcattc cgtgactttg cgaaagtaac acagccaatc atccaagcac
    42361 ttcatgaatt gggtgttgct ggggcggaat tgaaaggccg aaatgatcta gtcattgatg
    42421 gcatgaaatt ttctggcaac gcgatgtatg ctaccaacgg tcggatgttt gctcatggaa
    42481 caattatgtt cgactctgat atcaatgaag tagtcaatgc attaaaagta aaaaaagaca
    42541 aaatcgaatc aaaaggaatc aaatcgatcc gttctcgtgt aacgaatatc aaaccatttc
    42601 ttccagaaga aaagcaaaaa atgacaacag aagaatttcg tcaagaaatc ttgttgaaaa
    42661 ttttcggcgt agagtcagta gaagaagtaa aaacgtacga attgactgat gaagattgga
    42721 aaaaaatcaa tcgaatctct gaggaatatt atcgaaattg ggattggaat tacgggaagt
    42781 ctccagattt caatttctct cgccaaaaac gtttttctat cggttcgatt gaagtccatt
    42841 tgaatgtctc agaaggaatg atcaaagaag caaaaatctt tggcgatttc ttcggactag
    42901 gagatatctc tgacgtggaa aaaaaattgg ttggacagaa atatgataaa gcatctctat
    42961 caaaaatagt cagccaaatt gatgtgaaga aatattttgg tgcgatagaa ccagaagaat
    43021 tgcttacctt actttattga aaataaaaaa tagcggaatc cacatatatg gattccgcta
    43081 ttttttatac aggattcggg taatttcgag agagttgaac agtgatccga tcaatgaaag
    43141 tatctttttc ctgcgttagt gttcctgtgt aacgatccgc tacgtctttc atcatcatta
    43201 agtcaaaacg ttcctgatca tctaattctt ctgtgatgcc tcgactaaat aggtttgtat
    43261 cgtaatgtgc actatgttcg caacaaatga cgaaatgttc ctcttgttcg tgtatcgaca
    43321 aataaatttt tcgatacagt ggattttcga tggcatgagt ttctctaaag gaatgctcta
    43381 aagcgtggat caaaagttga gccagatcgt catcgttgat aggaagttct tcgggaagat
    43441 ctgcttggaa ggttatctga atattccgtt tggcagctaa cttctggtaa cgcgctaaga
    43501 taagatttgt cacctggtgg ttgcaaaaag aacacagcat ttcgaaattt tttgcttctt
    43561 ctaatatctt ttccacatag tttttagctt ttgtttggtc cgtatgcatt aaatcttgca
    43621 gattctccat ctcttggaca aattccaggc gaagtgtatt tacttcttgg atatgctgtc
    43681 gaagctgctc ataatgttgc tccaacaaat catttttgat ttttaagaaa tctacttgtc
    43741 tccgatcttt gtcggtattt aagatgtgat cgattagatt gtagctgata ataacgatta
    43801 gaatgataat atataaaatc gtagaccaat tgatcgttgt ttgatagata cctaatgccg
    43861 tttggatgta aatcaagcaa tggataatgg ctaccaagac gatccaaggt gtacaagcta
    43921 cataaaaacg gttattctta tatgcttcgc caatgcatgc aagtgaagtg actaaagtgc
    43981 ttataacact agcaatatta gcaatcggca ttaattcagg aagttctgca ggagtaaaag
    44041 ttgcataaag cagaacgccg ataaaaatca aaagttggaa cgtacaaaaa attccgtacc
    44101 attttttata gtaaaacatt cggctccaat agtagcagat gatgaaagct gacgttaaga
    44161 taataaataa atgagataaa aaagaatgaa cgaatggttc aaaaagaata ccacttaaaa
    44221 tatcttctga tacagcttca aatcctaatg ccaaagcaaa gcaacttaag agaataagtg
    44281 agtattcaag acgtttttgt ttatacatca agtagatcgt atagaaaaag gtccctatag
    44341 cgataaaaac agcgattatc atcgtcaata cttgcggcac tgattgtgaa taaataaaac
    44401 taatcaatgg tccagttgtt cctagataaa ctttcggtgg cagtccagca tagttctgat
    44461 aaggagatga gactgtaagg gtcaattttt ttccgatata atttgctggt aaatctatca
    44521 cagccaatga gagtccggga ttgctttctt cctgataatc tttccgttgg tataaaatct
    44581 tttcgcctag atatacagta atccattgat ggtttccttt gattagtaaa tttgcttcgt
    44641 ccaacggttt ttcaagtgtc gtttccataa tgaatgtttc gtctttatcc acggtaggaa
    44701 tcgtacgagt gtacttgctg tcaaacttaa aatcaggatc atcttttgta tagaaaaccc
    44761 acgaatcttt tatttctttc atttgattgc tgtccgcagg agaaaaaata aaataaaaga
    44821 aataagcaat tcctgttaaa aataacaat
//
LOCUS       DAMEEU010000015        44828 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.015, whole genome shotgun sequence.
ACCESSION   DAMEEU010000015 DAMEEU010000000
VERSION     DAMEEU010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 44828)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44828)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44828
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.015"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..1008)
                     /locus_tag="PB779_000853"
     CDS             complement(<1..1008)
                     /locus_tag="PB779_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDE0738395.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(1188..1532)
                     /locus_tag="PB779_000854"
     CDS             complement(1188..1532)
                     /locus_tag="PB779_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDE0738396.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(1525..1959)
                     /locus_tag="PB779_000855"
     CDS             complement(1525..1959)
                     /locus_tag="PB779_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HDE0738397.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            2097..2834
                     /locus_tag="PB779_000856"
     CDS             2097..2834
                     /locus_tag="PB779_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738398.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            2827..4038
                     /locus_tag="PB779_000857"
     CDS             2827..4038
                     /locus_tag="PB779_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738399.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            4242..5024
                     /locus_tag="PB779_000858"
     CDS             4242..5024
                     /locus_tag="PB779_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HDE0738400.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            5094..5756
                     /gene="trmB"
                     /locus_tag="PB779_000859"
     CDS             5094..5756
                     /gene="trmB"
                     /locus_tag="PB779_000859"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HDE0738401.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(5854..7608)
                     /gene="ade"
                     /locus_tag="PB779_000860"
     CDS             complement(5854..7608)
                     /gene="ade"
                     /locus_tag="PB779_000860"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HDE0738402.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKERLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNNQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            7740..8669
                     /gene="tadA"
                     /locus_tag="PB779_000861"
     CDS             7740..8669
                     /gene="tadA"
                     /locus_tag="PB779_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HDE0738403.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            8626..9675
                     /locus_tag="PB779_000862"
     CDS             8626..9675
                     /locus_tag="PB779_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HDE0738404.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            9672..9950
                     /locus_tag="PB779_000863"
     CDS             9672..9950
                     /locus_tag="PB779_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HDE0738405.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            9925..10395
                     /locus_tag="PB779_000864"
     CDS             9925..10395
                     /locus_tag="PB779_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HDE0738406.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            10412..10714
                     /locus_tag="PB779_000865"
     CDS             10412..10714
                     /locus_tag="PB779_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738407.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            10731..11102
                     /locus_tag="PB779_000866"
     CDS             10731..11102
                     /locus_tag="PB779_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HDE0738408.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            11074..11433
                     /locus_tag="PB779_000867"
     CDS             11074..11433
                     /locus_tag="PB779_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738409.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            11605..12612
                     /locus_tag="PB779_000868"
     CDS             11605..12612
                     /locus_tag="PB779_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDE0738410.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            12637..13821
                     /locus_tag="PB779_000869"
     CDS             12637..13821
                     /locus_tag="PB779_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HDE0738411.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(14258..15841)
                     /locus_tag="PB779_000870"
     CDS             complement(14258..15841)
                     /locus_tag="PB779_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDE0738412.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(16419..16562)
                     /locus_tag="PB779_000871"
     CDS             complement(16419..16562)
                     /locus_tag="PB779_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HDE0738413.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(16785..17264)
                     /locus_tag="PB779_000872"
     CDS             complement(16785..17264)
                     /locus_tag="PB779_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDE0738414.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(17337..17621)
                     /locus_tag="PB779_000873"
     CDS             complement(17337..17621)
                     /locus_tag="PB779_000873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738415.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(17699..17893)
                     /gene="ssrS"
                     /locus_tag="PB779_000874"
     ncRNA           complement(17699..17893)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="PB779_000874"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(17965..19251)
                     /locus_tag="PB779_000875"
     CDS             complement(17965..19251)
                     /locus_tag="PB779_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HDE0738416.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKNAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            19389..20060
                     /locus_tag="PB779_000876"
     CDS             19389..20060
                     /locus_tag="PB779_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HDE0738417.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            20026..20514
                     /locus_tag="PB779_000877"
     CDS             20026..20514
                     /locus_tag="PB779_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HDE0738418.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            20527..21474
                     /gene="prmA"
                     /locus_tag="PB779_000878"
     CDS             20527..21474
                     /gene="prmA"
                     /locus_tag="PB779_000878"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HDE0738419.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            21475..22239
                     /locus_tag="PB779_000879"
     CDS             21475..22239
                     /locus_tag="PB779_000879"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HDE0738420.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            22472..24685
                     /locus_tag="PB779_000880"
     CDS             22472..24685
                     /locus_tag="PB779_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HDE0738421.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            24696..25142
                     /locus_tag="PB779_000881"
     CDS             24696..25142
                     /locus_tag="PB779_000881"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HDE0738422.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            25313..26572
                     /locus_tag="PB779_000882"
     CDS             25313..26572
                     /locus_tag="PB779_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HDE0738423.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(26661..27608)
                     /locus_tag="PB779_000883"
     CDS             complement(26661..27608)
                     /locus_tag="PB779_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDE0738424.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            28002..29294
                     /locus_tag="PB779_000884"
     CDS             28002..29294
                     /locus_tag="PB779_000884"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HDE0738425.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            29309..31078
                     /gene="aspS"
                     /locus_tag="PB779_000885"
     CDS             29309..31078
                     /gene="aspS"
                     /locus_tag="PB779_000885"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HDE0738426.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            31187..32062
                     /locus_tag="PB779_000886"
     CDS             31187..32062
                     /locus_tag="PB779_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDE0738427.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            32328..34211
                     /locus_tag="PB779_000887"
     CDS             32328..34211
                     /locus_tag="PB779_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDE0738428.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(34286..34570)
                     /locus_tag="PB779_000888"
     CDS             complement(34286..34570)
                     /locus_tag="PB779_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HDE0738429.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(34560..35294)
                     /locus_tag="PB779_000889"
     CDS             complement(34560..35294)
                     /locus_tag="PB779_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HDE0738430.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            35423..36046
                     /locus_tag="PB779_000890"
     CDS             35423..36046
                     /locus_tag="PB779_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HDE0738431.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            36238..37359
                     /locus_tag="PB779_000891"
     CDS             36238..37359
                     /locus_tag="PB779_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HDE0738432.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            37366..40494
                     /locus_tag="PB779_000892"
     CDS             37366..40494
                     /locus_tag="PB779_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HDE0738433.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            40513..43707
                     /locus_tag="PB779_000893"
     CDS             40513..43707
                     /locus_tag="PB779_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HDE0738434.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(43853..44560)
                     /locus_tag="PB779_000894"
     CDS             complement(43853..44560)
                     /locus_tag="PB779_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDE0738435.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
BASE COUNT        14381 a         7961 c         9407 g        13079 t
ORIGIN      
        1 ttttgatgaa tcagttgttt cttcagttga agattctttt gttgaatcag ttgattttgt
       61 gtcagaactc tttgttgaag ctgtagtttc acttgagtct ttcgtacttg atgaagttgt
      121 tgtgaatgca ctcaacacat tttcaaaggc atcatctttg atttttacat ttgcatcttt
      181 taattcttca ccgattactt tagttgtgaa tgcattgtca cttagtttag tttcagtagc
      241 gatatctttt agttgatctt tgtatttatc catgtcattg cctttatttt ggtttttcac
      301 cattttgaca acgtagtatt ctgtcgcata agaagtagga tttgttgtag taataacatc
      361 ggagatctca ccgtctttca atttgaaagc tgcttctttt acttctgcag gaatagttgt
      421 tgtcgttgag tcgaatttaa ctttaccgcc atcttctttt gtctctgtat cagttgattt
      481 gtctttggct aatttagaga aatcatctcc atcatccgct gattttttca catcttttgc
      541 ttcatcttca cttgataatt tgatgatttg tgcttctact tctggatgga aagatttcca
      601 agcagttttc aaatcgtcat ctgtaatatc tacgtgagct ttcaagccag cttcaaaagc
      661 taaattgtta cgaatatatt ctttataagt atctttcgta tatccagcag cttctaattg
      721 tgattcaaaa gtatcaccta atgatttcgc ttgtttgtcg tattctgcat ccacttgctt
      781 atcggttact ttatcgccat atttgttatt gaatacttta taaatgatca tccgttgtac
      841 taaggattgg ttcgatgatt caagttttgc ttcatcatag aaatcagata cagtgatcgt
      901 tccgcctttc atcgttgcga tatctttatt agtatcgcct gaacaagctg ctagagttaa
      961 aacagccaac gcactagtag ctgccaaaat aattgatttt tttttcatta aaatttgcac
     1021 tcctgtaatt agttattatt tttatatatt aactatacca tatcccattt cctttaaaaa
     1081 cgttgtcgtg gtagtttcaa acaaaattca aaatttcatc acattcctag gaaatacgca
     1141 aacttttctc acttatatag ttaaatctgt tgagaaaata atcattatta tatttgttca
     1201 ggatactctg gcagatcagc ttttagtttt tctacttgtt cattgatttg tgtgatacgt
     1261 ggttcggctt ggaatttaaa atcttcgata tcttttttga ttgcttcttg gaaagcagga
     1321 atcacagatt cagctgtttc ttttgtttcg atcaatgcgc ttttaaaatg attcaggctg
     1381 ttatttaaat catttgtcag agttgttgct tcttccaatt cttcgatcag tttctttctt
     1441 gtttcattcc cgctcctggg cgccaataac agacctccga cagtgccagc agcagctcca
     1501 aataacagtc ctttgaaaaa gtttttaatc atcgcaggac acctgcttta cgattgtttc
     1561 ttgaatagct tttagttctt ccgatccata actatcttga tgattgacaa agtgaataga
     1621 aaaatcatcc tctttgctgt agcgagggac taaatggata tgtgaatgaa aaacagattg
     1681 ataggctagt tcacggttgt tattcaagat attaagacct ttcatttctg gaaaagcttt
     1741 ttccaatgct tgagcaatct taggcacacg cgaaaaaacc tctcctgcaa gttcgggatc
     1801 atattcaaaa atatctgcta catgacgttt aggcacaact aatgtgtgtc ctttcgttgc
     1861 ttgagagatg tctaaaaaag catagacctt gtcgtcttca tatattttat agcttgggat
     1921 ttcttgattg atgattttgc aaaaaataca gttttccata taaaacatcc tttctataaa
     1981 gaataaatac ttcagcttaa ctttaccata agttaaagct attgtaagga aaaaaacaaa
     2041 ataccgtcat tttcttcgtg gtataataaa taaaaataaa tggcggagga aaaagaatga
     2101 gtttaattat cgatcatgtc acaggggggt acggacatct ccctgtgtta aaagatatca
     2161 gtttcgatgt acagcctgga gagatagtag ggttgattgg actgaacgga gcagggaaaa
     2221 gtacgaccat caagcacatt atcggtctgc tggaagcttc aaaaggaacg atagaaatca
     2281 atcatctatc cttaaagaaa aatacggaag aatatcgcaa acaaattggg tatattccag
     2341 agactccttc tttatatgaa gaattgacat tgagagaaca tatcgaagtc actgcgatgg
     2401 cctacgatat acctatggat atagcaatga aaagagcaga aaagttgttg gagacttttc
     2461 ggttatctaa tcgtcttgac tggttcccag ctaatttttc aaagggaatg aaacagaaag
     2521 tgatgatctt atgcgccttt ttgatcgagc cttctttata tatcatcgac gaaccatttt
     2581 taggcttgga tccactagct atcaatgcat tgcttgaatt gatggtagaa atgaaaaaag
     2641 aaggagccgg tattttgatg tctacgcata ttttagctac tgcagaaaaa tattgtgatc
     2701 gttttgtggt cttacataac ggagagatac gagcagacgg ttctcttgag atgttgagaa
     2761 aagaatttca gctgccggat tcttctttgg acgaaatcta tattgcttta acaaaggagc
     2821 aggcacatga gtagtttttt tcaaaaacgt ttagcaagac atcaaaagaa aatgatgaaa
     2881 tatatgcgtt atgtattgaa cgatcatttt gttttagttt gtcttttctt gattggcggt
     2941 gtgggattat attattctaa ttggttgaaa accctgcagc caccgtttgc aattggaggg
     3001 ctcataatct ctgtattttg gatgctctgt ttattcgtgg gtaagatggc tacttttgca
     3061 gaggcagcag atattgtttt tttacttcct aaagaaaaag aaatgcaaac ctatttggaa
     3121 cgagcttttc gctattcttg catttttccg ttgatctttt tgatattggc atgcggattg
     3181 gccatgccat tagtggtggt tagtacggag caatcctttt cgatgttttt cgtctatctg
     3241 atcatattat ggagtttgaa attcagtcat ctgcaaatca agagagcaga attgtttcga
     3301 ctagatcaac aagttattcg ttattggaaa ttaggctggt ttttttcttc tctgatcttt
     3361 ttgtttctat cattttattg gctaatatgg gcaggaatag caggtgcatt agtacaggca
     3421 agtctatatt actggttttt gtggaagcaa caagaaaaag gattggattg ggagaaaatg
     3481 gtgcatgtag aagaacatag gttgcatcag atctatcaat ttatcaattt attcacagat
     3541 gttcctgaaa ttacggcaaa gatcaaaaga agacgctatt tggatcctat attgactcat
     3601 attaaaagag aatcaaaaaa cacttatctt tacttgtttg caagaagatt ggcaagaggt
     3661 tctgatttta gtggtcttta tttccgatta gtaattatag gtgggttatt gattgccgga
     3721 gtagtcgact tttattttag tctgattatc ggtttcttat ttttatattt gatcggtttc
     3781 caactgttac ctttagcgaa ccagttccgc tatatggttc tcgttcagct ttatccaatc
     3841 cataagaatc agaagaagca ggcgattcag tatctactca catgggtatt aattatcgcg
     3901 tcggttattt ttggtttgat tgctgcagtc gtattagatg ggcagcagcg atgggttccg
     3961 ctagcggctt atttgattgt tactatgctc tttgttaaac tatatgtacc aactcgtttg
     4021 aagaagatgt cagactgaaa acaaagctgt gtagggtaaa aatgagaatg aaaaatagag
     4081 cgttgacagt aagaatgctg ttcgttctat tttttttgag aaaagctggt tttttgaatg
     4141 gcaattaaat gaaaaagaac gtatatgtgc ttgacgtgta gtgttcaggc gactagaata
     4201 ataagtactg caaaacaaag agtaagagga cgggagaatg catgatggag tttcagttag
     4261 accaagagtg gcggttacgt cccatcaaag gcgacacagg aaaaacatac ataggcatgc
     4321 gtgatgagga caaagtcttt attaaacgaa acacgactcc gatgttggct gctctttcaa
     4381 gggaaggaat tacaccaaaa cttgtttgga caaaacgaac ggggaatggc gatactttga
     4441 cagcacaaga gtggctggaa ggtcgcttgc tgactcctaa tgagattggt caaagaaacg
     4501 acgtgattga tgttttgtac catttacatc attcaaattc tcttaaaacc atgctgaccc
     4561 gtatcggtgg tcgtgtcatg acgccggaga agatgctgca aaaatatgaa aaagaattac
     4621 cggaagaact ccagaaaaat caatttctgc aaattgtcca tcgttttctt cgtgagcaga
     4681 tcccgtcaat agataaggaa aacttatcag tagtacacgg agatgtaaac catcgtaatt
     4741 ggttagtatg taaaaattat ttatatctag tcgattggga ttcaatcatg tttgcagacc
     4801 ctgcggtgga tattgcaacg attttaggaa attatgtgcc actgtctagc tggaatcagt
     4861 ggctgatcag ttatggcata cgcccgactg acgaaatgct tgaaaaattt cattggtatg
     4921 cggccatgaa tttgctccaa gaaatcacca gatattgcaa acgtgaagat catcgacgga
     4981 tgaacgaaga aattttacaa ttaaaacgaa ttttcagtgg ctgaggtttg gcccaaactc
     5041 tgcggagatt tggccagacc tttttaatta gaggaaagga atggagataa ataatgcgtg
     5101 tccgaaatcg tccgggagca gcggaaatgt tagcggctca cccgaatttt gtaattagtg
     5161 atccaacatt gtggaaggga aaatggaatg aattgtttga aaacgatcat ccaatccaca
     5221 ttgagattgg tatggggaaa ggccagttca tcactggaat ggcaaaagcc catcctgaaa
     5281 tcaattatat tggagtagaa atgcaggtca gtgttgtttc gattgcacta gacaagttga
     5341 tcgaacaacc gcttcctaac ctgaaacttc tacatgtgga tggatcagcg ttgacagagt
     5401 atttcgctga cagcgaagta gatcaaatct atctgaattt ttccgatcca tggccaaaaa
     5461 aacgtcatga aaaacggcga ttgacatata agacttttct tgctgtagat gaacagattc
     5521 ttcgtccaaa tggagaaatc catttcaaaa cagataatca aggattgttt gagtattctc
     5581 tggcaagttt ttctcaatat ggcatgatcc tcaaacaggt atggttagat ttacatcaaa
     5641 gtcaatttga aggcaatatt atgacggagt atgaagaaaa attttcttca aaaggtcaac
     5701 gtatttatcg agtagaagct caatttcaag ataagaccaa aaagaaaagt ctgtgaaact
     5761 aactttctgc tttcataaaa acattaatat ccataaataa atcccagaaa atgaacatta
     5821 cagatgtaat gtattttctg ggatttattt gatttaaaat gtatttattt catcggtttt
     5881 tccacaaggt ggaatcaatt ggaagcgaga aaatgaaaat aatcctttgt cggtgatctt
     5941 caattcgggt atgacagata atgttaagaa agaaagtgtc aaaaaaggat caaaggtttt
     6001 agctgctcct agttgatgtg ctttagttat taattcattc aactgttcat agacgatcga
     6061 aaaaggttcc tgtgtcatga ttccgcctat aggaagagaa acacaagcta tttcctgctg
     6121 attgttgaca acggtcatcc cgccaccttt ttgaatcaaa agattagcag catacagcat
     6181 atcctcgtcg tttgtcccaa cgacaactag attatgcgag tcatgggcaa tcgttgtcgc
     6241 tatcgctcct tgtttcagct gaaatccttt cactatgcct aatccaatgt ttcccgtttg
     6301 atggtgacgc tcgatcaccg caatctttaa ttggtctttt tcgattgaag gaatgaatcg
     6361 ttcgccttgt cggtccactt tttctaccaa atctttagtc actagactat tcgggataat
     6421 ttcgatcaca tgggcttgtg aagaagaaag aagcagctct aacgaatgtg gatttaatgg
     6481 ttgagcgttt agttttggca gacaacacgt atatgaattt gaatgatcag caaataaatg
     6541 gtcttggagt tgcccagatt gaacaactaa tgttccctta tagaaaactt catgaattgg
     6601 cagcttggta agatcgtctg ttaagaagaa atcagcttga tacccagggg caatcgcacc
     6661 tagtgttttc aaatcaaaac attctgctgc attcaatgtt gccatctgaa tggcttgtaa
     6721 tggatcgatt ccaagtgcaa tagcttgacg gacgatatga tcgattgatc cttcttttac
     6781 taaatcattg atcagtttat catcggtgac aaagaagcat cttcttgaat tttcaggtgt
     6841 gatcgccggt agtagcgatg ccagatcttt tgcaacggtc ccttctcgaa ccattaaata
     6901 cataccaaga tccaaacgtt ctttagcttc ttttgcagtt gtagcttcat gatccgtccg
     6961 aatacctgct gcaggataaa catttaactc ttccatgccg ataccagctg catgcccgtc
     7021 aatttttttc ttatgctggt gcatcaattg gatcttttct aggatgtctg tttcattatt
     7081 tgctactgct tgatagttca tgacttcagc taagcctaaa acttcgggtt tttgtaaaaa
     7141 aggggctaat ttttttgcat ttaaatttgc accattggtc tcaaaagggg ttacaggtac
     7201 acaagaaggt agcataaaaa agatattcat gagtgtttgt cttgcatctt ctatcataaa
     7261 ctcaagacct gtactcccag caatgtttcc tatttcatgg ggatctgtca ctacagtagt
     7321 aactccatga agcaaggata cttttgaaaa ttcgcttggt gataaaagtg agctttcgat
     7381 atgcacatgg ccatcgatga atcctggcac tagatattgc ccattagcat tatgtacgct
     7441 ttttccttcg tattcaccga ttcctacgat cattccttcg cagattgcta catctttttc
     7501 catgatttct ttcgtaaaga cgttgacgat cttagcatgc ttgatcacta ggtcagcagg
     7561 ctttttttta cttgctactt cgatatattt ccttaatgtt gtttccaatg gagtgcctcc
     7621 caagataaat ttttataagt ataacataaa ttcggttttt gccaatattt ttttgtaaat
     7681 tcattttatt tgaaacaaaa agatcaaaaa gacgtatgtt ttttgtggag gggagaataa
     7741 tggaaataaa acgattatcg gatcaaatga taagtgaaag ttttgccaaa catgcccaag
     7801 acgtatatat attgccagct tcagaagtat tttacatcta ttttcgctat ggaaaaaaac
     7861 gaacattctg gaagaaagtc tcttcggcag atggacagca actgatctca agatttaagt
     7921 atttgggaca gatggatatc ggagaaaaaa gaaaagctca gttaggtgca tttacttatt
     7981 ctttagaaaa acaggaagtt cgtctgcggt tgtcttctgt aggagattac cttcaacgag
     8041 agagtttagt gattcggcta ttatacggta cttttgaaac accccatcgt tgctttagtt
     8101 ctcgagattt tgcaactatt ttacagaaaa ccgtcagacg tggattatac cttttcagcg
     8161 gaccagtcgg atcaggcaag acttctctaa tgtatcggtt ggctttggaa gaaaaattgc
     8221 aagtgattac tatcgaagat cctgtagaga tagaagaacc gttttttctg cagctacaga
     8281 tcaatccgaa aatagcacag acttatgata cacttttgag actcgcatta cggcatcgtc
     8341 cagacttgct aatcattggc gagataagag atgaatcaac tgcacatgct gcggtaagag
     8401 cagcactaac agggcaccgg gtttttgcaa ccgtacatgc acgcaatctt gaaggtacat
     8461 tggtcagaat ccatgaactg acaaagaaaa aagaagagct atctgaatgt ttagctggtg
     8521 tcatttatca agaacttttg gaagatgcca atcaccatcc ttctgtttta tggagttatc
     8581 aatttatgga ggaagaatca gtaaaaaaat catgggagga aagttatgaa gaagctcagg
     8641 aaaatatttg gcagtcagaa ctattctaaa ggattaacaa gaagccagca aaaccagttt
     8701 gcacaaacca tgggagaact gcttttatct ggttttagtc tgcaagaatc cctttattta
     8761 ttactcacga tccgttcgtt tccacctgtt attttggcaa atatccaaca tcagctaaag
     8821 gaagggcaag cgtttagtga ggtactttcg caaataggat atggagcaga gcaactggta
     8881 cagatcgagt tagctgaacg tcatgggaat ctgccgacaa ctttgttgga aattgccaaa
     8941 cagtttcggc ttgttgaagg atttcgcaat gatttgaaaa agctgcttgc atatccgatg
     9001 ctattgctca cctttttgct aggtatcttg tttagtatgc ggttgttcgt tttgcctcag
     9061 cttattggtt caggaatggt catgcaagag cattggggta ttcagctgat acaagtcttt
     9121 cattggtatg ttctactatt catcctagcg gttactctat tggctttact agtaaggtat
     9181 cgtctgatga agttgtctcc tgttgatcag agtgaatgga taagcagaca attattgatt
     9241 ggaccgatat attccttgta tcaatcggct tatttgtcac tagagattgg aaagcttttt
     9301 catgaaggtt tcgaattaag gcaaatcata gtctgcttaa aggaaacgaa acaagaaagt
     9361 ctgattcagc atcttgcctc taagttgatt caaggattgg aggcaggtat gtcattggct
     9421 gagcagttcc agaattatcg ttttctatca gaagaattca gtaaaattgt tttacaggga
     9481 gaggcaaagg gaagtttagg taaagaactg attttttaca gcgaatggac aagaaaacag
     9541 cttttcaaac gtcttcatca ctggatgcat tttattcagc caatcatttt tttgggcgta
     9601 gcggctttga ttttattagt ttatgccgct gttttattac ctgtttacgg aagcatagag
     9661 gaggttttgc catgaaaaag agaaaaatat cttattatag cggttttaca ttgatcgaaa
     9721 tgctaatcgt cttactgatc atcagtgtat tagtgttgtt gttcgtccct aatttgtcgc
     9781 gttataggaa tcatgtagac caagaaagtc gtgaagcgat catccagttg gtagacacac
     9841 aaaaagagct ctatgcgctt caaaataatg gaagagttcc tactgtggag gaattgttga
     9901 atgaaggcta tatcaaacga gaacatgcag aaatctatca gcggccttga aggtaaggtt
     9961 ttagcatcag gatatacgtt gtttgaatca ctcttactga ttttattact tacaacgatc
    10021 ctttcttttc cagttctcgc attttctgca tggaagaatg aattggcagt ctatcaattt
    10081 ttcggccaat ttgaaaaacg aatctattct acgcaaaaaa tcgctattgt gaatcagatc
    10141 caaacaggct tttattggaa tagtgaagag aatcaaatca tttttcatgt tccgaatcca
    10201 gataaaataa attgggaagt attagatatt cctgatgaga ttaccttgaa acgccatgct
    10261 tctattactt ttgctgctag aaccgggaat gaaagttcac taaaagctta tcaattttat
    10321 tgggaagaaa aagagcggac gattacgtat caattccaga tagggagtgg tcgctataca
    10381 aaaagaattg aataaaacag gatttgtttt gttggagtcc cttacagcgc ttatgatcgc
    10441 ttctgtctgt gtctacttag tgagctttgg ccagctgttt ttgcttcagg cagaaaagaa
    10501 aagtggggag gaactgctat ttattcgaat gatttatgaa gatatcaaga cgcagcggat
    10561 gtatcacaaa agaccagagc gaagggaaga aatgatccca tacgatatcc aaattgtcga
    10621 taataatgga gtaatcgaaa aagtgtttgt caatatggag aaagaagcga tcagtattga
    10681 aaaaacaagt aattccagca tttacgctga ttgaatgtct aattggactg atgatattga
    10741 gcagtctatt gctcacattc aatcttttga ttcagcaaac catccaagta agtgaatttt
    10801 tgcagcgtaa agatcaaaaa gagtggctaa tatttttagc acaattagaa gaagaactca
    10861 agagcagtca caatgtctct gtgaaaaatc agcaactgca ctacacgatc gaggataaac
    10921 agtatatcat cgaaagatat caggcaatga tacgtaaaag aagaacttcc ggcggacatc
    10981 aacctatgtt aacaagtatc actgagcttc aattattgga aaaagaacac acaatttctt
    11041 tttatgtaca ctttgaaaat ggagaagatg gatatgccat atggacaaaa aacgatcagt
    11101 agaaaatgtt ataagggctc tattttattt tctgtcttgc ttttatttct tttatgtacg
    11161 tttttattga tggcagcatt agaaagctac cgtttgtcaa tggatcttaa tatacgaatc
    11221 aaaaattatt atatagcaaa aataatgaag cagatggctt tatcggaaca gtctacgctt
    11281 gccgaaagtt cggaaggagt tttttactac acaactggat ctgtaacata tcagtgggta
    11341 caacagtccc tattcttaga ggtggaagtc tcaccgttta tctttcggtt cacagaagaa
    11401 gtaaaaaatg atacagatac tagtacagaa tgatggaatg ttcgtgaaaa cgccctcttt
    11461 tctgttataa cactgttttt aataaaaaaa tgtttgccgt ttcacaaata aaaaacagtg
    11521 aaaacgattg aaattttgtc aattgttcga tagaattaaa caggtgaaaa aattgttata
    11581 atatatctag aaatgaggtg caccatgtta ccagaaaaaa tggaacaagg gtttaatcaa
    11641 aacctggaag ctattcagct tttacagaat gcattgggaa cttccttttt agaagcctat
    11701 gtcgaaaatg cagaaaattt aatagatgat tatcaagtac gtgtggtgga tggagtgccg
    11761 acaaaagaga caacgcaacg gatcacagct ctttatgaag agttgaagaa actttctttc
    11821 gagccagaag aatggcgcag actgtctcaa ttacttttat tgaagggcag ccagacagaa
    11881 catttgcagg cgaaccatca actcactcct gatagtatcg gttttttatt tgtttttctt
    11941 attgaacaac tatacacaaa taaaaaagca ccggttaaga ttctggatat tgcggcagga
    12001 atgggcaact tgttattaac agttctttta aacctatcga atgcggggta ccaaacagaa
    12061 ggaattggtg tggatattga tgatacattg ttggctgtcg cagcttctac aagtgatttg
    12121 acacaagcaa atgttcaata ctttcatcaa gacgggttgc aggaattatt aatagatcct
    12181 gtcgattttg caatcagcga tttgccaatc ggttattatc cgaatgacga aaaagcaaaa
    12241 gagtttttaa caagtaccga agaaggccat agttatgcac atcatttatt gctagagcaa
    12301 tcaatgaaat atgtgaagcc ggatggtttt ggtttgtttt tgatgccgag tggattttta
    12361 gaaacggatc aaagtgaaga aatcaaaaaa tggtttaaag aagaaggtta tcttcaagga
    12421 atgattcaat tgccagatga attgttccgt aataaacaat cgcaaaaaag tattttgatc
    12481 ttacagaaaa aaggaccaca agcacaacaa gtaaaagaag tcttgcttgt gaaacttgct
    12541 tcattaaaag aaccagagaa ggtgacggaa tttttcaacg agtttaaaaa ctggaaatca
    12601 tctgctctgt aatcattcaa cgagaaggag agtcatatgt ctaaaacaat tgcaatcaat
    12661 gctgggagtt caagtttgaa atggcaatta tatcaaatgc cagaagaaac cgtagttgcg
    12721 aaagggatcg tcgaacgtat cggtttacaa gattctattt ttaccatcaa gtacggcgat
    12781 aatcaaaaat tcgaacaaat catggatatc gaaaaccacg aagtagcagt aaaaatgctg
    12841 ttagatcagt tgattgaact gcaaatttta agctcttatg atgaaatcac cggagtaggg
    12901 caccgtgttg ttcacggagg agaaacttat ggggattcag tagtgatcga tgagaaagta
    12961 atggaccgca ttgctgaatt agcagaattt gctcctttgc ataatcctgc aaacttaatg
    13021 gggatcaaag cgtttaaaaa gattttacct gacattttga gtgtggctgt attcgataca
    13081 tctttccact caacaatgcc aaagcaaaat tatttatata gcttaccggt gtcttattat
    13141 gaagatttca aagtaagaaa atatggcttc catggcacaa gtcatcgtta tgtgtcggaa
    13201 cgtgcggcaa aattattgaa caaaccgatc gaagaactaa aaatcatcac ttgccactta
    13261 ggaaatggtg tatcgatcac agcagtcgat ggaggtaaat ccatggatac ttctatggga
    13321 ttcacaccat tagctggggt gacaatgggt acacgttcag gtgatatcga tccagctgtt
    13381 ctcccatatt taatggaaaa attagagatt gatattgatg aaatgatcaa tgttttgaac
    13441 aagaaatctg gtctgctagg cctaacagga ttgtctagtg atatgcgtga tcttgaaaag
    13501 aactatgaaa aagaacatat tcgtttagct tatgacattt tcgtggaccg catccgaaaa
    13561 tacatcggcg gttatgtgac aacgatgaat ggtgttgatg caattgtctt tactgctggt
    13621 atcggcgaga atgacggaca tgtacgtagt gaaatcatca aaggtatgtc ttggtttggt
    13681 tgtgaaatcg atccagcgtt gaatgaattg cgtggtgaag aagtagatat ctctacaaaa
    13741 gaatcaaaag taagagtatt agtgatccca acagatgagg aactaatgat tgcccgtgat
    13801 gtggagcgtc tgcgcggcta agccaaagca ttcgttagga taaaagatga aacgcatgca
    13861 agagggaatt cttgcatgtg ttttttttgc ggagaagacc gcaaaatggt aatttaactt
    13921 caatttccct tcttttttac aggatcttct tagggaattt tgcttggaaa agtggtcaaa
    13981 agggaaaaga ctggcatttt atttattgat tttcaggaaa atcccaatat tttattttca
    14041 ttcatcttta taagggacat tacatatgta aaaagaaaaa acatttttag atcagcctcg
    14101 tgggctgtcg actttattct tcgctttatg tttagctaga aaaccgatcc gaaacattca
    14161 ttgatcgaat aataaaaact tgattttcca cctgtacttt gcctgaatcg tgaaagcaca
    14221 ggtatgaaaa tcaagttttt tgttgcgaaa aaacgtccta gtcaatcagt tggccgagcg
    14281 gctggcggct gatctgctcc tgatcaataa cgagtgcttc ttggaagtgt tgctgcaaaa
    14341 agtagcggtc atggctgact gctaggagcg ttccttgata gtcttgcagc atttcttcaa
    14401 tttcttctcg agcatagctg tcgaggtgat tggttggttc atccaaaatc aggacgttga
    14461 ttttttctaa aaagagtttc agcaacgcca aacggatttt ttcaccaccg gataaatctt
    14521 tgatccgttt acccacatcg ctttgataaa agccactttt ggctaattgc cgtcgagcga
    14581 cttcttcgtt tccagtcaat gtgatggcgt aagccagcaa acggctatcg ggatcggcaa
    14641 actgcagctg ctgcggcaaa taaccgattt gcaagctact acctaatttg atggtgccac
    14701 cgtaaggctt ttcctcaccg agtaataatt tgagtaaggt tgattttcct gcaccattgt
    14761 cgccgatgat ggctaaatga tctccacgat agactgcaaa actgctgtct ttgaatagta
    14821 cttgatcagc gtactgctgg tgcaagtttt gaatgatgaa aacttctttg ccagattttc
    14881 caccattaga caagctttgc agccgatttt tcgggggagg tggcggtttg acgagtgtca
    14941 gtttcgccag gcggcgttcc agttctttgg cttttttgaa gaaggactca ttgtctcctt
    15001 catgtgccca ctgacgaaaa cgacgaatca tgactttcaa ccgctggact tctttttgct
    15061 gcagttcgta attttttgtc agctcagcca agcgagcttc tttcaagact cgaaaacggc
    15121 tgtagtttcc gggatactca atcaatgcac cttcttccag ttcccatgtt tttgtggtga
    15181 cttgatcgag aaattgccga tcatgagaaa cgaccagaac cgattttttt gtattctgta
    15241 aatagttttc caaccagcga atactgttaa gatctaaatg attggtcggt tcatcgagta
    15301 aaagtaaatc ggcatcggct gctaaaattt tggctaaagc gactttaact cgttcgcctc
    15361 cgctaagttc tgttaaccgt gcttcctgac ggtgtggaat ccctaagcct tgcaagatcg
    15421 ctgcaatccg gtcttctaat acgtaaccgc ctagttcttc aaagcgatgc tgcagctcac
    15481 cgtaacgggc cagacacttc tctaagtttg tatctggttc tgtcatcaat gcttcgtagc
    15541 gactcatttg ctgtttgagg tcctgtatct cagcggcaga atggagcaag tagtggttga
    15601 cggtcgcttc ggaaactgta agttcttgtt cgaccgtccc gatctttaag ccttttttgc
    15661 gactgataac accgctgtcg acaccttctc tgccggtcaa gatttgtaaa aaggttgatt
    15721 tgccagttcc gttgataccg actaaggcaa ttttttcacc agcttcaatt tgacaggata
    15781 aatcctcaaa taatggattc ccgccgattg tttttttaat agaaattgct tgtatgatca
    15841 tgatctctct ccttgagacc actcaaaaag gccatggtta tccatggcct gtgttattta
    15901 aactcagatt atcatgagaa aaataccttg agatggccat tgattttacg tgaattcaac
    15961 tgttttggac aaacttgtcc cgtcaacagc aactgtaaaa ccaattgcat ggctaaatgc
    16021 gatatggtat cgttggtaat tttcattact tgttatttta gtcatgcgca tcatagtatt
    16081 ttccctcctt cgtgtagttg tcttttccag tgtacctgaa agtgtcagaa agttcaacta
    16141 gcgctgacat ttacttaata tttatcgatg tgtaattctg tcagagagct ttttttatct
    16201 gactgagggt aatgtctcgt ggaccacatc attgtattct gagctaaacc agcgttcagg
    16261 cgaaatcata tggtgtttga taaaaaactt tgtctacatg acttcctttt gccatttgct
    16321 taataccgtt gcattaaaca gctcttctct ttggaaatct caccaacatc gcgttcagga
    16381 gtatcgttgt ggttgcaatg gcaagcggta gcctttcatc aattcttgaa tgatttaccg
    16441 aatgtagcac ttgccttctc gcggtacccg aacccgaaat aaaattttag tttggcgata
    16501 aaatcggtat ccgccatcga tacttcatat tttttcgtat cagattcatc ggaaacttcc
    16561 acattgacga accaataagc tttggcatgc ttaggtcgtt ttaaaccaca ccagggcgac
    16621 taatcgccct ggtgttcact tttttttatt ttacttgaac tcattgactg ttttcccttt
    16681 attttaaaca ttataaagac cgatgagtgc ttgccgcgtc ttttgttttt atcacggttt
    16741 tttgtgcaaa aaaacctgcc gatagttggc aggtcgtcta cgtgttaagc tttggtgtgg
    16801 tctttagctg gcaattggtt ttctaaatca gttcggacaa caagcacatc gcaagctgcg
    16861 tttctaataa catattcaga aacagaacca ataaataaac gttctacagc attcaatcct
    16921 gtggctccta acataatcaa atctacttga ttatcttctg ggatttctct ggcaataatt
    16981 tgttttggtg agccatattc tacgacagag gttacattat tcaagccagc tttcttcgca
    17041 ttgctttcat aatctgccaa tgtttgcttt gccatttcag tagcttgttc tgcaagcatt
    17101 ccatcaaagg atgaaacggt ttggaaagaa cgtgtgtcaa tgacatgtgc taatagaagt
    17161 tctccgttat ttcggatagc tacattgacc gcctttttaa aagctaattc agcttcatca
    17221 gaaccatcta cggcaaccat gatttttttg tattgttgta acataagcat tcactcctca
    17281 agtcaatcgt attgtactct tttattgtag aacactttag ggaaaaagag aattatttac
    17341 tgctttggtt cagcaatttt ttttgcaaat cggatactga aggtggcaga aacaataatt
    17401 acgatcagta aaaagaccaa ggcaataaag cgttgattga aaaaagctgt taaaataccc
    17461 attacgccta aaacagcata tgcagctccg taaaattgta ggaatccttg atttttatca
    17521 tttttgttga tcaatacaaa aaagatatcc tgtttattaa ataaataata gctaacgaat
    17581 aataatacta aagtggcgat aatcattaaa atcctaatca tgaacaaatc ctccaaaata
    17641 agcaacaaat agaaaaagca atttgccaag agcaaattgc tttattcttt aaaagatggt
    17701 aatctccgtt aatgccgttg tttgtcctgt agtattgatc ccgcgaattc aagcaggtgg
    17761 gtcccatggt cgtagcttcg aactaccaaa tgataaggca tgttaccagc agtgacacaa
    17821 gacgggtccc aagatatcaa taaaaatgtt cggtcaacac acaaagagga caattcgaac
    17881 atcacagatt tcccacctct atagtagcat atgaatttaa aaagagcaat gagagagctc
    17941 gcagaaacag aaccgttttc ttgtctagtt ttttggagga tgctttttcc actcttttat
    18001 acggtaatac tgttgaccca gagcctgttc atatttccct gtatcttttg gctgataata
    18061 ctgagcattc ttcagtttat ctggtaaata ttgctgattg acccaagcct gatcaaaatg
    18121 atgaggatac tgataaccca cgccacggtt gagtgatttc gcacctttgt aatggctatc
    18181 tctcaaatga tcaggaacat ctccagcttt gccctctcga atatcagcaa gtgctgcatc
    18241 taatgccatg taggcagaat tggattttgg cgacaagcaa agatcgacga cgacgtctgc
    18301 tagtgggata cgtgcctcag gcaatcccaa tttttcagca gctaatacag cgttcactgt
    18361 acgagccgca gcagcaggat tacctaaacc tatatcttca taaccgataa ccatcagacg
    18421 ccggcaaata cttgccagat cacctgcctc aactaaacgg gcgagataat gaagtgcagc
    18481 atccacatca cttccacgaa tcgatttttg aaaagccgaa ataacgtcat aatgagcatc
    18541 tccatttttg tcatgggtaa gagcttttct ttggacacat tcttcaatga tcgacagtgt
    18601 aagatgaatc cttccttctt tatctgaagg agtcgatagt gtagccagtt ccagcccatt
    18661 caatgcactc cgcaaatcgc cgttcgttgc acgcgaaagg tgaagaagag catcttcgtc
    18721 taactggatt gcttgttgtc caaggccgcg ttctttatcc cttaaagcat gttcgactgc
    18781 caactggatg tcttgttctg ttaatggttt gacttcaaag atctgtgtac ggctgcggat
    18841 cgctggattg atggtaatat aaggattctc agtagtcgct ccgatcaaga tgattcggcc
    18901 actttctaaa tgaggaagca gaaaatcctg ttttgtttta tctaatcggt gtacttcatc
    18961 caataagagg atcactgtac cactcatttt tgcttcttcc gctacaactt gtagatcctt
    19021 ttttgaatct gtagcggcgt ttagcatgcg aaatgcataa ttagtagagc cggcgatcgc
    19081 acttgcgata ctcgtttttc cagtaccagg aggtccatat agaatcatgg aagagagcat
    19141 gcgagcatcg accatgcggc gtatgatttt tccttccccg actagatgct gctgaccaac
    19201 gacttcatcg atcgttcgag gtctcatgcg ataagccaat ggctgttgca taggattttc
    19261 ctccttcttg tttttacgtc ccttaattat atcatattta gcaagatgcc tagaaagaac
    19321 agccttctgt tgttttgttt tcatagctta tccaactaat attgtgtatg ataaagtagg
    19381 tgagaaaaat gacggataaa caaaagatag atgaattttt ttggaataaa acgacgccag
    19441 aagtggcacg ggatttattg gggatgtatt tggagcatga cacaccagaa ggaagattag
    19501 ctggatatat tgtagacgcg gaagcatacc taggtccaga agacgaggcc gcccatagct
    19561 atggtttaag aagaacaccg cgtgtgcggg caatgtatga aaaaccaggt acgatctacc
    19621 tttacacgat gcatactcat cggattttga acatcattac tcagccagaa gggattcctc
    19681 aaggagtaat gatacgtgca atcgaacccg ccgcaatgat tgatcaaatg agtaaaaatc
    19741 gtggcggaaa aactggtcca gatatcagca acggtccggg aaaattagtg gaagcattag
    19801 caattcctca agaactttat ggtcagtcta tagcagatag ttcgttacgc ttagtttttg
    19861 agaaaaaaaa gacaccaaaa aagatcaatg ctttgcctag aatcggtatc ccaaacaaag
    19921 gtgtatggac agaaaagccg ttgcgttttg ttgtgtcggg aaatccttat atctctttac
    19981 aaagaaaaaa ccaaatcgag aaagattggg gttggaggaa agaaaatgaa aaagaaggat
    20041 ctattaacat atttagatga aataattgaa aaacaagtga cagactatga tgtagcttta
    20101 gattgggata caaaaaatca tacgatcgag atcgttgttc gcttgtttgc agaaaataaa
    20161 gcacaatttg agattgatga tgcagaaggg atcgtttcgc aagaaccaat tatcgaattt
    20221 gaagacggcg tacttctttt taatcctcag aaatctgttt ttgatgaacg caattatcta
    20281 gcagtaatcc cttatgaagg aaaaaaaggg ttggcaaaat cagtagctga ttctttagtg
    20341 gaatatctaa atgaagtatt agctcaaggg caaagcgatt tgcttgattt tttggatgaa
    20401 gacgatgacg aagctgtatt cgagcttcac tgggataatc agcaactagc agaattagta
    20461 gaagtaaaac agcaaaatga agcagatact tatttaccgt acccaagtta ttaaggagtg
    20521 acagatatga aatggaatga agtaaaagta gaaactgaaa gtgaagcagt cgaagcagtt
    20581 gctaatattt tgatggaggc aggggcgagt ggtgtcgcga ttgaagattc tttagatgtt
    20641 gaacattttc agtcggatca atatggtgag attttagata aaaatgattt tacatcgctg
    20701 aaagaaggcg cactagtcat ggcttatttt ccggaaacga ctttcttacc ggaaatcttg
    20761 ccttttatca aagatcgtat cacacaatta cctgagtttg gtctagctat tggaaaaaat
    20821 aaagtaacag ttagtgaagt agaggaaagc aactgggcaa cagcctggaa gaaatactat
    20881 catccggtgc gtattacgcg aatgctgacg gttgcgccaa gctgggaaaa ctaccagaca
    20941 gaagatcctc tagaaaaaat tatcacacta gatcctggta tggcatttgg cacaggcact
    21001 catcccacga cttccttgac attgacagca ctagaaacag tcttgcgtgg tggtgaaaca
    21061 ttgctagatg tgggaactgg gtcgggcgtg ctaagtattg cagcaaaata tcttggtgca
    21121 aaagatgtct atgcctttga tttagacgaa gtagccgttc gttcggcgaa agaaaatatg
    21181 gatatgaatg aaatagccaa agatgtccat gtatcagcta acgatctttt gacaggaatc
    21241 gagattgaaa gtgatgtaat cgttgcgaac attttagcag atatcatctt attgatgatc
    21301 ccagatgctt ggcgtttact gaagcaaaca ggcacgctga tcgtttcagg aatcattgaa
    21361 gagaagaagc aaatggttct ggatgccatg ttagaacaag ggtttatcgt ggatcaaatt
    21421 ttccagcaaa aagactggta tgcaattatt ttgaaaaaac cagaggtgga atagatgcag
    21481 cggtattttt taaaagaatc atatgaatca aaagactatt ttgttttaga aggggaaaac
    21541 tatcaccaca ttgtacgggt tatgaggatg gaacccgagg atgaagtttt tttggcattc
    21601 aatgatcaaa tagccattgt tgcagaaatc acggagatta ctgaagaggc tgtttatctg
    21661 aaagaaatta aaaaagaaga aaatcaaaag gaactgccaa gttcgattac catagcgagt
    21721 ggctatccta aaggggaaaa gctggattgg atcgttcaga aatccactga attaggagcg
    21781 caagcttttc ttggtttccc ggcatcagcc tctgtcgtta aatgggatgc aaaaaaacgt
    21841 atgaaacgac aacaacggct tgaaaagatt gctcaagagg cagcggaaca atcccatcgg
    21901 cagatcgtgc catcagtaga gttattggaa acgaaacaag atttatttga gcggctagat
    21961 gattatgacg tggtcttggt tgcttatgag gaatcagcaa agcaaggcga aaaatcaaat
    22021 gcagccaaaa ttcttagtga aacaaaacca gatagtcgaa tcttagctgt ctttggacca
    22081 gaaggtggat tatcccgcga tgaagtcgat tattttgtag aacacaaagg gatactttgt
    22141 ggattaggac caagaatcct tcgtacagaa acagcacctc tttatttatt aagtgctgct
    22201 agctatcaat gggaattaat gaatccttct ttcagctaac gttcttcatt aataaaagag
    22261 tatcgacaga aagaattgaa aaaatagtca acaatttgta taatagaaac aattatttat
    22321 acaatggata cgaaaaatcg tttgaaaaag cttttaaaaa gcgaacattt ccgtaaaaaa
    22381 acgtataact gcacggattt tgggacaatt atcaaacaga tatttgtccc gattcccgtt
    22441 ttaccgaaaa aagaaagggg gatcgattcc tgtgacaaaa gaagaaattt taacgggacc
    22501 cggtgtcata aagctcgtta gtcaatacat gggtcccgaa catgtagcat ttgttgagaa
    22561 agcatgcgaa tacgcgactg ctgcacatga cggacagttt agaaaatcag gcgaacccta
    22621 cattattcat cctatccaag tcgcaggtat attagcagat ttaaaaatgg atccccatac
    22681 agtggctaca ggcttcttac atgatgttgt tgaagataca gaaatcactt tagaagatct
    22741 gagagaagaa tttggcgatg acgttgctat gttagtggac ggcgtaacca aattagggaa
    22801 aataaaatat aaatcccacg aagagcagct agcagaaaac caccgaaaga tgctgctagc
    22861 aatggctcaa gatttacgag ttatcatggt caaattagct gatagactac ataacatgcg
    22921 tacgttgaag cacctgcgag aagataagca aagaaggatc gctcaggaaa ctttagaaat
    22981 ctatgcgcct cttgcacatc gtctagggat cagccggatc aaatgggaat tagaagatac
    23041 agcacttcgt tatctaaatc caaaacagta ttaccgtatc gtccacttga tgcagacgaa
    23101 gagagaagaa cgtgaaaaat acgtaagtgg tactgttgaa gatattcgaa tagcgacaga
    23161 agagctgggg atttttgcag aaatctatgg acggccaaaa cacatttatt caatctatcg
    23221 taaaatgaaa gatcagaaaa agcagttcaa cgaaatttat gacttgctag ctattcgagt
    23281 gatcgtagat tcaatcaagg attgttatgc tgtattagga gcaatccaca caaaatggaa
    23341 accaatgccc ggcagattta aggattatat tgccatgcca aaagctaata tgtaccaatc
    23401 tttgcatact accgtgatcg gtccggcagg aaatccggta gaaattcaaa tccgaacaca
    23461 ggaaatgcat gaaatcgctg aattcggggt tgctgcacac tgggcctata aagaaggaaa
    23521 aaatgaaaaa gtagaaccag atggtatgac gaaacaatta agctggttcc atgagatact
    23581 cgaacttcaa gacgaaagct atgatgcttc tgaatttatg gaaggcgtaa aaggagatat
    23641 ctttagtgat aaagtctacg tcttcacacc aaaaggagac gttactgagt taccaaaagg
    23701 atccggacca ttggactttg catacagtat ccatacagat atcggtaaca aaaccactgg
    23761 tgcaaaagta aatggcaaaa tggtgcagct tgattacaaa ttgaaaaacg gagatatcat
    23821 tgagatcatg acttctccaa attcatttgg cccaagtcgc gactggttga aattagttgc
    23881 tactagcaaa gcaagaaata agatcaaacg tttcttcaaa gcccaagatc gagaagaaaa
    23941 tgtgatcaaa ggccacgaat ccgtggtcaa atgtattaca gatctaggat ttacgcctaa
    24001 agatattttg acgaagaaca aactgcaaga agcactcgat cgttttaatt atcaaacaga
    24061 agatgatctc tatgcagctg tagggtatgg agaagttagc cccttgacga tggccaatcg
    24121 tctgactgaa aaagaacgta aagaacaaaa aatcgagcag caaaagcaag aagcagaaga
    24181 aatcatgaat cagccgaaaa aagaacctga caaaatgaaa gtacgtcatg aaggtggcgt
    24241 tgtcattcaa ggggtagaaa acttactaat tcgtatcagt cgctgctgta atccgattcc
    24301 tggtgatgat atcgttggtt atatcactaa aggcagaggg atatccattc atcgtcgaga
    24361 ttgtccgaat gttcagcctg acaaaccaaa tgtagcagaa cgtttgattg aagtcgaatg
    24421 ggaagataca tcgaatacac gaaaagagta tgatgcagat ttggaaattt acggctataa
    24481 tcgttcaggc ttattgaatg atgtacttca aacagtcaat gcgctaacga aaaatctcaa
    24541 cagcgttgaa gcacggacga ataaagataa aatggcgacg atccatttga cggttggtat
    24601 ccagaattta tcccacctaa agagtatcgt ggataaaatc aaagcagtac ctgatgtcta
    24661 cagtgtacgc cggacgaatg gataggagga cagatatgag agcagttgtt caacgggtaa
    24721 gtaaagctgc tgtgtcagtc gatcagcaag aaattggaaa aattggctac ggcctacttg
    24781 ttttattagg cattcatgaa accgatacgc aaaaagatgt ggactatctg gtaaaaaaaa
    24841 ttgcacaaat gcgtattttt gaagatgaac aaggaaaaat gaatattagt gtagaagatg
    24901 tgggaggaca aattttaagt atctctcaat tcacactgtt tgcggatacg aaaaaaggaa
    24961 atcgaccaag ctttgtggaa gccgcacgac cagaaacagc tattccttta tacgaatcat
    25021 tcaatgaagg aatcagaagt cgcggcatca cagtcgctac cggacaattc ggagcagata
    25081 tgtcggtttc tctcgtcaat gatggacctg taacgatcat tattgattct aaaaacaaat
    25141 aaagtaatct ggttttcact agtaaaaact atgaaacacg tcgcttaagt tagactgata
    25201 aactctaact taagtggctt ttttgtctgc aaaaagcgct tcttttgtca gcagtcggaa
    25261 aaaaagttaa gcttaaatta tacaagttat tttttatagg aggttgctga agatgaaaga
    25321 agtaccagta gtagatatca aaatcacaga tttaaaaaaa ttgtatcaaa aaggatacaa
    25381 catgttggag gagttacgcc atgaagcgga cgctcccgtc gtcaaagcaa agattttcaa
    25441 taaagaagct atcacgatct acggatcatc agcagcaaaa gtattttatg atccaaggaa
    25501 tttcaaacga aaaggtgcta tgccaaaatt agtattgaag acactttttg gtcaaggtgg
    25561 agtacagact ttggatggag ctgctcatca ccatcggaaa aatattttta tggatctaat
    25621 gacaccggaa agaatggaag attatcatcg tatcttagat aagaatctga cacaagcact
    25681 tgaagcacag catggtcaat ttgaactatt tgatttaagt aagatggttt tctttacatc
    25741 tatttgcgag tgggcaggta tcaatttatc agcgatttct aaagatgagg tcgaaaaatt
    25801 agcagaatat caaatctcta tgatcagcgg aacgtttact tctccgattg atcacataaa
    25861 aggtgtcgaa aatcgcaaaa aatcagaaaa atgggcgcaa ggcttgattg aagaagctcg
    25921 acaaaatcct gtggctggaa aagaaaatgt ggcattatat gcttttgcca atgccacaga
    25981 tttagatggt cagcttttac ctctggaagt ggcagctgtt gaattattga acatcatccg
    26041 tccaacggtt gctctaactg tgtgggcggc attgatggga catgcacttt tcagtagacc
    26101 agatttgtat cagcaattaa aaaatgactt ttcgacgtta caagatccgt ttattcaaga
    26161 aatgagacgc tattatcctt tcttcccaat gctacctgcg atttcgctga aagaagtaga
    26221 agtagatggt tatcgtatac cagaaggcag ttgggttatt ttagatttat atggaacaga
    26281 ccatgatgaa cgaacagttg aagcgccaga ttcctttatg atcaaacggt atgtagggaa
    26341 agcaaaagat atttcctata aagaagaata tgagatgatt gcacaaggcg ggggaaattt
    26401 tcgacaaatg catcgctgtg caggagaatg gatcactctt catagtctac gtgtgttttc
    26461 cgatcagcta gtaaataagt ttgagttctc tgtacctgaa caagattgga cgattccatt
    26521 caatcagttt ccgacttatc cgaatagccg agcgctactt tacaagaatt agattagcat
    26581 aaacttatcg aaaaaaagga agatcaaaca gtgctgatct tccttttttc atattactat
    26641 aaattgataa ggtcaattga tcaaaatcca cgaaatgctt catcaatggt ttgataatct
    26701 tcattggata aatgcaaatc taaagcttgg acattgtcag atacttgctc tggacgctta
    26761 gctccaggta taactacaga cactcgtgga ttcttcatgt accaagctaa aacaagttgc
    26821 gcaggagtgg cttggtatct tttagcaatg gggcgaagta catcgacagc ggttaaaatt
    26881 tctctgaaac gttctccttg gaaatctgga tttctttttc gaggatctcc ttcaccaaat
    26941 tgtttttcct caccaagttc atattttcct gtcagcaaac cggaagcaag aggaaaatag
    27001 ggaacaaaac tgattttgtt tttttcaaga taagggaata attctttttc agcctgccga
    27061 tggatcaaac tgtatttatc ttctactaca tcgacatatc catctgcatt cgcttctttc
    27121 aattgttcta acgtgaagtt tgacacaccg actgctcgga tttttcctgc ttcttttaat
    27181 tcgtgcaatg tagcaactga ttcatttttt ggtgtgcttt catccggaaa gtggatataa
    27241 aaaatgtcga tgtaatcagt ttgcagacgt tttagtgcat cttccaccga ttgtttgaga
    27301 aactcaggag aattatcaaa tgttcgccct ttatttggta catgagcagc ttttgtagcg
    27361 atgacgacac gtgagcgatc atattctttt tccttcagta cctcgccaat cagttcttcg
    27421 gaacggccgt ttccgtaagc ataagcggta tcgatcaaat tgatcccgct attcaaagct
    27481 gtacgaacta cttgttttcc tgtctcatct tccaaaccgt caaaaagatt atgtcctcca
    27541 acggcatttg ctcctaatcc aagctgttct gcgtagactt gtgaatgtcc gattcttatt
    27601 tctgccatag ctgattcctc ctttttgtct agtctaaaac aaaataccaa aaagctgaac
    27661 taaaacgttt ttgtgagggg aaatagtcag atatctcttg actttgagac tggtttttag
    27721 taggttataa gtaatatcga atgtcaatga aagagcgagt aagtttttga aactttacaa
    27781 gagaggatca tcgaggctga aaatgatcta aagtttcatt agcctaaaga cactctggag
    27841 atggacgagt gaaaagccgt cccgcgtacg agcgttattc gtaagaggaa agagaaatct
    27901 ttcaaaatta ggtggtaccg tgtatgaatt tcattcaccc ttgttcatga tgaacaaggg
    27961 tgattttttt atttacatag ctaagaaagg gagagaaaac tatgagtttc caaagaccaa
    28021 aaggaacaaa tgatattttg ccaggcgaat cagaaaaatg gcagtttgtc gaagaaacag
    28081 cacgtttatt attcagagat tatcagtata atgaaatgcg tacaccgatt tttgaacact
    28141 atgaagtgat atcccgaagt gtaggggata caacggatat cgtttcaaaa gagatgtatg
    28201 atttttatga caaaggggaa cgccatgtga cgcttcgacc agaaggtaca gcaccaatcg
    28261 ttcgttcttt tgttgagcat aaattgttcg gcccagagta tgcgaaaccg ttcaaaactt
    28321 tttatatggg accaatgttt cgctacgaac gccctcaaaa aggacggtta cgtcaattcc
    28381 atcaaatcgg agtagaagca tttggatcag aaaaccctgc aactgatgtg gagagcatgg
    28441 tgatggcact tgatttcttc aaacagttgg ggatcacgca aatccggcta gtcatcaatt
    28501 cattaggtga taaagaaacg cgtcaagcct atcgtcaagc attgatcgac tatcttttac
    28561 cttttgaatc agagctgagt gaagactcta aacgccgcct tcatgaaaat ccattacgcg
    28621 tattggacag taaagacaaa cgagatcaaa aatttgtggc agaagctcca tctatcttag
    28681 attatctaag cgagcctgct caaaaacatt ttgataccgt tgtttccatg ctggatgcat
    28741 tggctgttcc ttatgaaatc gacagtaata tggttcgcgg actagattat tacacacata
    28801 cgatttttga aatcatgagt gacgcaccaa aaatgggggc acaagcaacg atttgcgcag
    28861 gcggacgtta tgacaatcta gtggaagaac taggtggtcc ttcaacacct ggcttcggat
    28921 ttgcaatggg tatcgagcga ttactcttga ctatggaggc agaggaagta gttatccctg
    28981 catttaatga gttggatgct tacgtggtcg cactcggaga cgaaacaaat atcgaagcat
    29041 tgaaagtggt ccaagcgatt cgaaactttg gtttttcagc tgaccgcgac ttcatgaacc
    29101 gtaaagcaaa agcgcaattt aagacagcag ataaagcgaa tgccaaatta gtattggtga
    29161 tcggtgaaga tgagcttgct agtcaaacga ttaatgtcaa agcaatggca agccgaaaag
    29221 aaaaaagttt tccattagaa gagatatatg aacattttga tgaagtctat gatgaaatga
    29281 ctttattcga gtaggaggaa aaaaataaat ggcacaaaga acgatctatt gcggattagt
    29341 ttccgaacaa caattagaac aaacagttac attaaaagga tgggtacaaa aaagacgaga
    29401 ccttggggga gtaatcttta tcgacctacg tgatcgtgaa ggaatcgttc aaatcgtctt
    29461 taatcctgaa atcaacaaag aagcatggga aatcgcggat aaatgtcgca gtgaatacgt
    29521 gatcgaagtg actggggaag ttagaagacg cggagaaaat gcagtaaatc ctaaaatggc
    29581 cactggtgaa ttcgaagtga ttgcaagtga aatcgtgatt ttgaatcaag caaaaacccc
    29641 gccatttcaa attgaagatg atcaagcaat cagtgacgaa atacgtttga aatatcgtta
    29701 tttggatctg cgtcgtccaa aaatgactaa aaacatcaaa ttaagaaatg cgacaacaaa
    29761 agcgattcgt cattatttag atgataatga ctttctcgat atcgaaacac cttacctagg
    29821 gaaatctaca ccagaaggcg caagagacta cctagttcct tcacgtgtcc atgctggaca
    29881 tttctatgcg ttgccgcaat ctcctcaatt gtttaaacaa ttgctgatga atgctggatt
    29941 cgaccgttat tatcaaatcg ttcgttgttt ccgcgatgaa gatttacgtg gagaccgtca
    30001 gcctgaattt acgcaagtag atattgaaac aacgttctta acagcagaag aaatccaaac
    30061 ttacacagag ggattgattg cgaaggtaat gaaagaagtt cgcggtatcg aagtcacatt
    30121 gccatttcct cgtatgacct atgatgaagc aatggctcgc tacggcagcg acaaaccgga
    30181 tacacgtttt gatatggaat tgatcgatct aagcgataca gtcaaagaag tagaattcaa
    30241 agtcttccaa atggctcttg aaaacggcgg tgtcgtgaaa gcattgaatg ctaaaggcgc
    30301 tgcagatcgc tactcacgaa aagacatgga tcagttaggt caatatgtag gacaattcgg
    30361 agctaagggg cttgcatggc tgaaagtaga agaagacgga ttgaaaggtc caattgctaa
    30421 attcatggga gaagcaacag aagcaatcat taaagcaaca gatgcaaaac caggtgactt
    30481 gctgatgttt ggcgcagata aaagtgaaat cgtcgctgct gcattaggtg ctatccggac
    30541 acgtttagga aaagaattag gactaattga tgaatcgaaa ttcaatttct tatgggtaac
    30601 tgattggcca caatttgaat tttcagaaga agaaggtcga tatgtctctg ctcaccatcc
    30661 attcacgatg ccaaaagaag aagatatccc gttattggct gaagaccctg caaaagtcta
    30721 tgcagaagct tatgatatcg tcttgaacgg ttatgaacta ggcggaggtt ctatccgtat
    30781 tcatactcgt gagcttcaag aaaaagtact agaaactcta ggctttacaa aagaacaaat
    30841 ggaagaacaa tttggtttct tgttaacagc tttagattac ggattccctc cacatggcgg
    30901 tattgcatta ggattggacc gttttgcaat gttattagcc ggagaagata atattcgtga
    30961 agtcattgcc tttcctaaaa acggaaaagc agcagatgtg atgagtgatg caccaagtat
    31021 ggtttcgcct ttacaattgt tcgaattgaa tattgatgta acgaatatag aagaatagcc
    31081 gataaaaagg taaaaaggat ttgtcgaata cgcttctttt gacaaccttg atttaattga
    31141 aaaacacttt ataatgaagc cataacatat aaagcggggc ttttccatga aaaaaacatt
    31201 cgaaaattgg gcttatcatg attacacgac caagctttcg gtatctatcg tttatgcgtt
    31261 gatcgcatca gtcgcattga atttctttta tcagccagga catatttatt caagtggtat
    31321 tactggtcta gctcagattt tgacgacttt gtcaaaatca ctgataggat tcgaagtacc
    31381 ggtatcaaca actttgtatt tactgaatat acctttgttt gtattggcgt ggttaaaaat
    31441 cgggaagaag tttacaattt tcacttttat cacagtcact ttgacctccc tttgtatcca
    31501 tattttaccg gaaacagtcc tatctaccga tccaatcatc tgtgcgttgt ttgggggggc
    31561 tgtgatggga ctaggtattg ggctagcgtt gagaaacggc ctatcatcgg gcggtctaga
    31621 tatcgtgagt atcacgattc gtaaaaaaac aggaaagtcg attggttcta tttcgatcta
    31681 cttcaatgca ttgatcgttt ttgttgccgg aattctattt ggctggcaat atatgtttta
    31741 cagtacgttg tctattttcg tcagtggaaa agtaactgat gtcgtttata ctaaacaaaa
    31801 gaagatgcag gtaatgatcg taacgaaaca tccagaaaaa gtagtaaatg aaatccaaaa
    31861 ctgtatgcgt agagggatca cgatcatcaa tgaagcagaa ggtgcttata agcatgataa
    31921 gcagacagta ttgatgacga tcgttacacg atacgaactg cctctactta gagaagcaat
    31981 gaaagcttct gatccacaag cttttgtaag tattgcagaa aacgtccaga tacttggtcg
    32041 tttctatgag gatggcattt agatcgagtt tgacaaaaat tcatgaaata ctgctgtaga
    32101 cagacgttcg tttgtctgca gtttttttct accatagtag aatcagcaaa gaaaaactgc
    32161 ttttttattt gaaattttct taaagttgaa aaaaagcatg tttatttttt taaatttatg
    32221 ggatgataga aaaaaatagt agagaaagga cacgattcta cttgctattt tcacttaata
    32281 cccgtatatt acgaatgaaa aaagtttatg aaaagttgga atattgaatg gaaaaacaaa
    32341 aaaggttaaa aaacagccgc tacatcactg ggtttgatgg gctccgttca ttagctgtgg
    32401 tgggtgttat cttctatcac cttctgccaa ctagtatgaa aggcggctat ttgggcgttc
    32461 cgattttttt cgtcgtatct ggttatttga tcacggatct gctgcggcag gaatgggaac
    32521 aaaatggaaa aatcaatatt tggcaatttt atgtcagaag aatgaagaga ctctatccgg
    32581 cacttgtttt tatgcttgtg acagcttcgg cttatatcac tttgtttcag cgagggctgt
    32641 taaacaatct tcgaggagtt gtggtcagca gcttactgta tgtcaacaac tggtggcaaa
    32701 tcaataacgg tttatcttat ttcgatcgat ttgctaatga gtcaccgttt acgcatatct
    32761 ggtctttagc agtagaaggt caaaactatt tggtttggcc gatcttgttt gtattgttga
    32821 tggtatttgt tcgtaaaaga aaatggatct tttatactgt gttaggtaca tccttcctct
    32881 ccgccatctt gatgatgatc ttgtatacac caggaggcga tccaacccgt gtttattacg
    32941 gtaccgacac tcgtctgttt tctatatggt tgggaagtgc gcttgcgttt gtttggccaa
    33001 gtacgcgttt aaagaaaaac atcccgaaac aagcgaaaaa tattctgaat atcgctggag
    33061 gaatctcgct tttggcactg attctttgct tcttcttttt agatgatcat tacaatttca
    33121 tctattacgg aggaatgctc ctagtgagtc tgttatgcgt agtgctagtt gcagtgacag
    33181 cacaccccgg agcaagtttg aatcgatggc tgacaaatcc agtatttact tggattggca
    33241 aacgaagcta tggcatttat ctgtatcagt ttccagttat gattttttat gaagcaaagg
    33301 tgactgatat tgccgatcat gttttgttgc atactttagt ggaaatcaca ttgattctaa
    33361 tcatcagtga actttcttat cgatatgtgg agcgtccgct agcacgtttt gattatggtc
    33421 gtacattcca agtgatgaaa ggatggttca gcaaaccgat catcagtaag agcaaaccat
    33481 gggttgttcc aggcacatta cttgtagcaa ttgcactcgt tggtttcgtt acggcaccga
    33541 aaaacgctgt aacagccgat caaaaacaac tgcaggcaaa aatcgctgaa agtaaaaaat
    33601 tagcagaaga aaccagaaac aattcagaaa acaccactag ttcggttgac caagcgatcc
    33661 ttgataagta cgagttgtcc aaggcacaag ggaataaggc acaaaaatta gaactaacgg
    33721 catttggtga ttcagttatg ttggatgctg caacggatct acaagaactt tatccaaaag
    33781 tagtggtaga tggagatgtc ggacgacaat tatatgccag tgtaccgtac attgaaaaat
    33841 taaaggaaca agatttgttg aaagacactg ttctgatcgg actaggaacg aatggctcat
    33901 tctcggaagc tcagtttgat agtgtgatgg atgcaatcgg tgatcgaaaa gtatactggg
    33961 tcaatgtccg agtaccgacg aagcgctggc aaaatgacgt gaatgcgatg cttgaacaga
    34021 tgacgaaaaa atacgacaat atgacgctga ttgattggta cagctacagt aatgaccata
    34081 gtgactggtt ttatgatgat caagtccatc caaatcctga agggatgaca cattacattc
    34141 acttagtcag cgaagccttg ctaggaggaa gttcaagtac gaacagcagt gagacaaacg
    34201 tgacagaatg atagctacaa aaaacttcag gcaaaaacat ttgtttttgc ctgaagtttt
    34261 tttatattta ccgtgttttt aacattcata tagattcagg aagcaaaacg gttgagtgtg
    34321 tctgtaaata acgttctttt tgttttcggg tgagtttttt gaatgcagct tctgcttttg
    34381 ttgcttcgct tcttgaagaa aatacttctg catggatcat cttaacaggt cttctttttt
    34441 gaagacgagt atatttagca ccagtaccat tgttatgttc ctctaatcgt ctagaaagat
    34501 cggttgtata tccaccataa aatgtctgat ctttacagaa taatacgtaa aaataatgtt
    34561 catttgccat agagcatctc acgaatctct gcagtgtatt ctccatccat attgtaagtg
    34621 atcaatggtg gagcgacttt gaatccgtct aatttgcctt ctttgattcc ttcaactaac
    34681 aaaatatttg cctcttttcc aggttttggg taaacaaatt ggatcctttt aggtgcaatt
    34741 cgatagtctt ccatgacctg aatgatttct aagaaccgat caggacgatg gaccatagta
    34801 aagcgtccat ttgtttttag tagcttactt gaaatatcga tcacttcttc taacgtcgta
    34861 tgaatctcat gacgggcgat tgccaggtgt ttattagggt tcgttttatt tgttggcagc
    34921 cctttgaaat aaggtggatt acagacgact aagtcacaag aattatgtcg aacgacagat
    34981 aagctgtctt tcagatcgat ggtgtggaca gtcatttgtt catttaaatg gttaagcgcg
    35041 atactacgtc ttgccatgtc tgctagacga ggttgaagtt cgatagcgtc gatagccgcc
    35101 tgggttcgtt tacttaaaaa aagtccaact gcgccatttc ctgcacaaag gtcaacaatc
    35161 ttcccttttt taggtacacg ggaaaagtga gcaagcagca cagcatctaa agaaaaagaa
    35221 aacactttgg aactttggat aatcttgata tcttctgcgt ataattggtc gattcgttcg
    35281 tcttcgtgaa gcatggattc cctccaaaat gaaaaaaata gtcgtctgta ttatactatt
    35341 tttattaaaa agaaccaagg tggcttgtca aacctctatt ttttatgcat actatgacca
    35401 taagaaggga aaggaagaga ctatgtttta tcgatttatg cgcggggtag ttcgagtact
    35461 attagcctta gttaatggaa atgcccgcta tgagaataaa gaagttttac cgcaagatga
    35521 gaattacata ctagttgctc cccatcgtac ttggtgggac ccattatatc tggcggtagc
    35581 tgcagcaccc aaggaattca gctttatggc aaaagaagaa ctgttcaaaa atccagttct
    35641 gcgatttata ttaactcgat ccaatgcttt tccagttaaa agagaaaatc caggaccaag
    35701 cgtcattaaa acacctgtaa agattttgaa atcgacaaat ttgagtttga tcatgtttcc
    35761 cagtgggaca agacatgcta cagaacttaa aggcggaatg gcattgattt ccagaatgtc
    35821 taaagcgaaa atcgtgccag ctgtatatca aggtccgttg acacttgggg atctgttcaa
    35881 gcgtcagaga gtgacagtgc gtttcggcga accaatcgac ttatcagata tcaagaaaac
    35941 ggataaagaa ggtatggcgg agatcgaacg acgaacacaa gcagcttttg acaaattgga
    36001 caaagaagtg aaccctgatt tcaaatatga agtcaaaaaa aaataaaatg ataagtttat
    36061 gcgtgggcgg tcttttgaat ctactgtcct gttcagttca gactttttca atgaaaacga
    36121 gggagagacg tcaagtctgc cctctttttg cgttccaata tgtaaaatag aagacaggtg
    36181 tcatgtaatg gatcaaagtg ttataataat tagaaggaca ttttttgagg tgattgaatg
    36241 cgttttttac atacagccga ttggcatatc ggaaaaaaac tacaaggtta tgacttgatt
    36301 gaagaccagc gtcatgtact atcttctata ctagatatcg cgaaagaaga aaaagtagag
    36361 gcaatcgtga ttgccggaga cttatatgat aggagtgtcc cagctgttga tgccgtagaa
    36421 ttatacaatg aattgatggt cgattggaat ttaaaggaaa agatcccgat ttttgctata
    36481 tcaggaaatc acgatagcag tacgagactt tcagcgggta cgccatggtt cagttattcg
    36541 aactattttt tgcgaacaca gctagcagaa gcatttgaac cagtcgagtt taaaaacgta
    36601 caatttttct ttcttcctta ctttgaacca attgcagcga gattatattt tgaagatgac
    36661 aatatccgaa cgatcaagca agcggtagcc aaggtgatag ataaaatgca ggagctattt
    36721 gattcagaaa aaaaacaagt attgattagc catttttttg taatgggaag tgtaaaatct
    36781 gattcggaaa cgaaaatcga agtaggcggg ttggattcga tccctggtga actacttaca
    36841 ccgtttgatt atgtagcact aggacatttg cataatcaag ctgctttgag acaggataat
    36901 gctcgctata gcggttcccc attgaaattc tctttatctg agatcaacca aaaaaaaggc
    36961 gtatggatcg ttgacctgac aacaggcctg gagttgaatt ttagggagat cgaacccctg
    37021 catgatattg aagaaataac agcgagtttc aaagaattgc tggatcctgc cttttatcag
    37081 tccgtcaatc gggagaatta catctatatc tatctcactg atagaacgat catcccgaat
    37141 atgatgaacc agcttcggca aatatatcct cgtattttgg ggattgaacg ggcaaacggt
    37201 cgagcagaac aaacaaagcg caaacgaaaa gtactagaaa tgaaagatcc tcaaaaatta
    37261 gcagaagcat tttttagtga aatgacggaa gagcagctaa ctgcaaacca agaaaaatgg
    37321 ctcggagaaa cgttgcaaga aatcatggaa atggaatgat caagaatgaa accgaaaaaa
    37381 ttacaactta aaaattttgg tccttttatc aatgagaccg tagatttttc acgtttgaca
    37441 gaagcaccgc tttttttgat cagcgggaag acaggagctg gcaaaacgac gatttttgat
    37501 gggatcacct tcgcactttt tggtgaaact tccggaagac ttcgctctgg aaaagagatg
    37561 cgttctttgt ttgctacacc agacgaagaa acaagcgtga ctttttcttt tgaacatcag
    37621 cagatgagct atgaaatcga acgaaaacca gaacaagttt tagcaaaacg aaaaggaaac
    37681 ggaacaaaaa aacaggcagc caaagtaacg ttgaccattt ttgatgggaa aggaaaagaa
    37741 ataaaacaaa tcacaaaacg tacagaagca gatcagttga tcagagaact gatgaatctc
    37801 gatgcgaaac agttttctca aatcgtttta ctaccccaag gagaattccg taattttttg
    37861 gtttcatcaa gcagtgataa agagactgtt ttacgtcatt tattcggtac tcaatttttc
    37921 caacagttca atgagcgatt aaaagaaaaa gcaaaacaac agcaacaaaa attggatcat
    37981 ttagagcaag agctgcatct tctgcaaaaa aggtttgttt tagtcaaaga agaggaacca
    38041 gcagcagggt ttgaagccgt tttagcccaa tggacaaacc atcaggcaat actcgaaaaa
    38101 caaatcacgg aagaaaaaga agctctaacg gaacttcagg aaaaacaaaa gcaactagaa
    38161 aattcctact atcgttttga aagcttgaaa aaaagttatg aagaaaaaac gatattaata
    38221 aacaagcaaa aggaattagc tgctcaaaaa gacgaaatag aggaaaagaa acgatggatt
    38281 gggtattatg aatttacgca acgattagtc gaaccaatcc agcgcctaca agaaataaaa
    38341 gttgaaaaaa tagaactgtc acaaaaaagt agtgagcaaa caaagaaact agcgatgact
    38401 acgcagaatt atgaagagtg gcaaaaaaat gaagcaaacc gcgtacgccg acaaacaaaa
    38461 atcaaagaag ctgctcaaaa actgcaaaac aaacagatga tggtgccaat tgtcgaatcc
    38521 ttacgtagta aaaaacaaga cgcagaacaa ttaacaattt cattggataa agaagaattg
    38581 aatgccgaga agctgtatca aaatctcgct atctatcagg aaagaactcg aattcttcaa
    38641 gaaaatttac tggatcagga aaaactgcaa gaagatcgtc ttgcttttgg acagttaaaa
    38701 tatctagatg aaaagcagca agaaatagaa aaacaaaaag caaaagacac tgggtcgctc
    38761 gcacagataa gagaagaact caaaaaagca actgaagaaa taacaaaaaa tagtcagcta
    38821 ttgaaagaac agacagaaca agcagaacag ctgaaaagcc aatgggcaaa gcagcaaatt
    38881 gctcgtcttc agcttttttt gcgtccaggg gagccatgtc ttgtttgtgg atcaacggaa
    38941 caccccatac aacaattaaa acacgaacag ccaaataagg aagatatctt aaaagtagaa
    39001 caacaactgg cagaagctga gtctgctgta gaaagaactc agcaaatcat tgccaaaagt
    39061 gaagcacatg aaaataatct tcaacaacaa ttatcagatt tagaacaaaa aatcatggca
    39121 acgaatatac aattggctga acaagaagaa cacttgcaac aggctttgaa aaaggcattt
    39181 cctgagataa cagaacaaaa aacaaaaaca actcttgtag taatcgaaca atctttagat
    39241 agacgaaaaa gcaagatggc caatgcaaga atagagctgg aagaaataag acaacaagca
    39301 gaaaagctcg aacaacaatt agctgtctac aaacagcagc agacagaaaa aaataatcag
    39361 ctccagcaac tgcaaggaga aatcaaaagt ttagaacaac aattgcaaga tacggatagt
    39421 aactgtttag aagaggagat acgacgactt gaaaaacagt tagaagaaga ctcgaatcaa
    39481 ctagctgttg agcagaaagc aggagtgcaa ttgttgcaag atcttcatac gcttcggaca
    39541 cagcttgatc ttcaacatga acaaatagaa aaaatagatg aaaaaataga aaaggaacaa
    39601 gaaagaatag ctaaaaagtt agaaagccag tcgtattttt caacaattga agaaatctgt
    39661 gcatttgcac aacagcaagc acaatataaa gaaaaccaac gtacagttac ttcttatcat
    39721 gaagagcaat tagtgacagc tgaccggctg cgtcaattag aaaatatcca gctaactgag
    39781 acattcccag atacagaaga gatcagccaa cagttagaag aaataagacg tatgatcgaa
    39841 ataaagcaag aaaagatata cggtttacaa gaacaaaaaa ttagtaatca aaaaatctac
    39901 gatgaatgtc tttcgattta tcacacaagc cagacgaaat tagatgagct tacgcaatta
    39961 cagcagcttt cgcaaacatt caacggagaa aatcctaaga agactagttt ggaacggtat
    40021 gtgcttcagg tttatcttca agaagtgtta caagtagcaa atgatcatct ccaacgttta
    40081 acgaaaaatc gttatcaatt tgagctagcg gataccattg gcagttatcg agggaaaacc
    40141 ggattagaaa tcaatatcta tgatgatcag gcaggtatgt ctcgaagtgc gcataccctg
    40201 tctggcggtg agagttttat tgcagcactt tctttagcat tagctcttgc cgatgtgatc
    40261 cagacacaag ctggtggtgt agcaatcgat gcattgttta ttgatgaagg atttgggtca
    40321 ttagatgaag aagctttgga aatggcaatg gaagctttag aaacgatcga aagtgaagga
    40381 agaatgatcg gcatcattag tcatgtaaga gaattgaaag aacgagtatt acaacaaata
    40441 agaattgata cagaaggtag cggacaaagc aaaatacgct atcaacttgg ataaaaaggg
    40501 agattggtaa ctatgaaatg gagtattcca gaaaaagtca ttgcacgtgg acgtcaatac
    40561 ttgcaagaag gccgagtgtt atcggttgtc cctgaccaag aagaaaacgt gtggcatgca
    40621 gaagtcttgg gcagtgaatt gtatatggtt gatttggatg gtacagcaaa agagatagat
    40681 tactgccaat gtccctattg ggaggaacat aaatattgta agcatacagt tgctgtggaa
    40741 ctttatttac ggtcgaaaaa tctatctcgt atcatgaaaa aagaccagcc aatgctagaa
    40801 ccggtaaaag caacaagtga gggagaaatc attgcaaaag gtttttctcg tctaaaaaca
    40861 caaaacaatc ctcaagcggt gcaacctttg attattgaat accaagtaga aacgattgag
    40921 actaatcagt atcacccaga gctttctatt ttggcacttt acttgcgtat cggttcattg
    40981 gcatcaccga aaaaaacata tatcgtaaaa aacatctatg attttttaca agcttacaca
    41041 gaaaaagaaa cttacactgt taataaacag taccagtttc gtctagataa acgggcgttt
    41101 caaaaagaag atcaaaaaat actcacgcat cttgcaggaa gtgctcagac gcatcaatta
    41161 ttaggtacga acggcttaca agtcaaagga aaactagata aaagatatct gcttctccca
    41221 gtagaacaag cccgcttcct gttagagcag atgaatcaga ctacacgttt gcatctgcag
    41281 ataaatgaac aaaacgatca aggaatacaa ttttccgatc aaaacaaacc tttatcattc
    41341 aaagtggaaa aatttggaga agattatttg ctgcaagcat tgaatgattt tgattttttc
    41401 tttatgcatt atcagtgggg agttatccaa gggacatttt attctctgac gaaatatcaa
    41461 caaacggttt atcaaacttg gaaacaattg attcgccgat tggagaaacc agaagtagtg
    41521 ttcaagaaaa aagaattacc gtctttgttt aaagagatta tccctctgct gtcagagatc
    41581 ggcgacgtag ctattgcccc tgcagtagaa gaggaagtag cagatatccc cgtcgaattt
    41641 attttctttt tccgaaaagc aaaaggaaaa atccaagctc gagtcgattt cgtctatggc
    41701 gaagtcatct attcgactga cccgaagcat gaggtctcga cagaacaggc ttttcaggtg
    41761 ttacgtgaca cagtagaaga gaaacgagta cttgatctat tcagaatgta tcgctaccag
    41821 aaaaatgaaa ctggttatga acgtccattg ccaagcgggg aagaactata tgcctttttc
    41881 cgcacagaac tatctgtctt ccgtcagttt ggtgaagtca gacttggaag aaaattgcga
    41941 gagttgtatt tagatgcgca taaacatcaa ccgaaaatcg aagtaaccga gaccggttca
    42001 tggctcgata ttcgattcga tgtgacaggg atagaggagc aagaaatcga tcatgtcctg
    42061 caaagcttgc tgagaaatga tgctttttat acattagaaa atggtcaggt tctttctttt
    42121 gattcagaag aatttcaaca aacaagccaa gtgttgcaac aattacggga atcgatacgt
    42181 acagaagaag gaacgatcca tgtacctaaa aatcaaggat tgatcattca aaatcaattg
    42241 gaaaaaagca atgctacttt tagtgaatcg ttccaaacga tggtacaaga tctcattcat
    42301 ccagaaagat accaggcaca gcttcccaaa ggattgaatg caacgatgag agattatcaa
    42361 aagcaaggtt ttcgatggtt gaagatgtta ggtcattatc agtttggcgg tattttagcc
    42421 gatgaaatgg gacttgggaa aacactacag acaattgcct ttttactttc ggaaaaagaa
    42481 gaacggaaaa gcttctctgc tttgatcgta gcgcctgcga gcttaattta caactggcag
    42541 gcagaggtga gaaaattcgc cccttcttta agtatccaag taatcaatgg gaataaaaaa
    42601 gaacgtgaag aattactggc taaagacaca gatatccgag tgacttctta tgccagctta
    42661 agacaggatc tagctaatta tcagtcgcaa aaaattgatt atttgattct tgatgaggca
    42721 caaatggtca aaaatagcag tacgaaaact gcacaagcat tgagagaatt agctgtacct
    42781 cagcggtttg cactgagtgg gacaccaatc gagaataatt tagaagaatt gtggtcattg
    42841 tttgcaacga ttatgccagg atttttcccg actaaaacaa aattcaggga acttgccgca
    42901 gaagaaattg cgcaaatgat tcgaccgttt attttacggc gagataaaca aactgtgttg
    42961 aaagacttgc cggaaaaaac agagatgaat ctatattctg cacttacaga agaacaaaaa
    43021 actgtttatt tagcttactt gcgtcaaatg cgtgaagaaa tcacatcaat ggattctgaa
    43081 gcattcaaga aaaaccggat cgggatactt gctggtctga caagactgcg acaaatttgc
    43141 tgcgatcctc gtctgtttat tgaagattac caaggcggtt ccggcaagct cgaacaagta
    43201 aaagatctac tggtagctgc caaagagaac aaacgaagag ttttgctgtt ttctcaattt
    43261 acagggatgc tgactatctt gcaagaagag ttagccgagc tagggatctc gacattttat
    43321 ttaagaggca gtacgaaacc acaagatcgg ttaagtatgg tagacgcatt taatgctggc
    43381 gaaaaagatg tttttctgat ttccttaaag gctgggggaa ctggattgaa tctcacggga
    43441 gcagatacgg tcatcttgta tgacctttgg tggaatcctg ccattgaaga acaagctgct
    43501 ggacgtgcac atcggatcgg acaaaaaaat gtggtagaag tgtggcgtat gatctctgaa
    43561 ggaacgattg aggaacgcat ggattcactc cagcaagaaa aacgcgaact gttccaaaaa
    43621 gtgatccaag gtaatgaaga acagttgacg aaactgactg aagaagacat ccgcatgatt
    43681 ttaagtgtag gagaaatcga ggagtaagag actcgaaaaa gcgttcagta atgggtaaga
    43741 aagcctttct aaagaagcga ttgtttattt gatttaaaaa atagcaagga ggctgggatt
    43801 ccattttatc ccagcttcct tgctatcatt tttttatttc tatttttaaa ggttatacaa
    43861 agattgtctt cattgtctct aacagctgat caaaagaaga aatctcgata tcgcaaattg
    43921 gagtctgttc aattttgcgt tctcgatggt tgaaccaaag cgcttgccag ttagcacttt
    43981 ttgcacctag aacatcattg tcgtaattat cgccaacgta taaggtctct tctggaagca
    44041 tatgaaattc tttctcagct agctgaaaaa tctctttttc tggtttttgg aaacctgttg
    44101 cttgagaaat gagcatattg cgggaaggaa tccaattgtt caattgaagt tgcttcagtt
    44161 tttttgtctg atggtcagtc ggcccatttg tgataattcc taatgggaca ttcttttcct
    44221 tcaagaaatc gagggttttt ttgacctcct catgcaagca gatattatca agttcttcct
    44281 cgtaaatttt ttgaaataag aggccatctt cttccgtaat atgagggtag tctaaatctt
    44341 ttagtgattg gctgatccga tgtgctcgca tatattctag tgtccaatct cctgccatta
    44401 cttttgggaa gttttcatca ctatgatggc ggaaccggat atatagtgga tgcatatctg
    44461 catctgaaac aagcggaacg actcttttga ccgcgtttcg aaatggctgc tgctgatcat
    44521 acatcgtatc atcaacatca aacacaactg atttaatcaa aattttacac gcctttcggt
    44581 tttcattgat tttttcacaa atccttgact attgtaacag aaaaaattgt ctaaaaaagc
    44641 tgataaataa aggtttttct tactatattt ctatttcctt gacagaataa ggtttttata
    44701 tttcagtttt tttcactaaa aatcgtgaaa cacgtcaata agtttgatga acaaattaat
    44761 cattatggta gaagtcgatt gatttatttt aatgcaatct ctgtggaatt ttcgaaagat
    44821 ttattttt
//
LOCUS       DAMEEU010000016        43619 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.016, whole genome shotgun sequence.
ACCESSION   DAMEEU010000016 DAMEEU010000000
VERSION     DAMEEU010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 43619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.016"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(259..2640)
                     /locus_tag="PB779_000895"
     CDS             complement(259..2640)
                     /locus_tag="PB779_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDE0738436.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(2630..3277)
                     /gene="recU"
                     /locus_tag="PB779_000896"
     CDS             complement(2630..3277)
                     /gene="recU"
                     /locus_tag="PB779_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HDE0738437.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            3341..3880
                     /locus_tag="PB779_000897"
     CDS             3341..3880
                     /locus_tag="PB779_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HDE0738438.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            3970..4389
                     /gene="gpsB"
                     /locus_tag="PB779_000898"
     CDS             3970..4389
                     /gene="gpsB"
                     /locus_tag="PB779_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HDE0738439.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            4411..4778
                     /gene="rnpB"
                     /locus_tag="PB779_000899"
     ncRNA           4411..4778
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="PB779_000899"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            4987..6153
                     /locus_tag="PB779_000900"
     CDS             4987..6153
                     /locus_tag="PB779_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HDE0738440.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            6199..7695
                     /locus_tag="PB779_000901"
     CDS             6199..7695
                     /locus_tag="PB779_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HDE0738441.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            7776..8459
                     /locus_tag="PB779_000902"
     CDS             7776..8459
                     /locus_tag="PB779_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDE0738442.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            9104..10294
                     /locus_tag="PB779_000903"
     CDS             9104..10294
                     /locus_tag="PB779_000903"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HDE0738443.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            10396..11349
                     /locus_tag="PB779_000904"
     CDS             10396..11349
                     /locus_tag="PB779_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HDE0738444.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            11418..12767
                     /locus_tag="PB779_000905"
     CDS             11418..12767
                     /locus_tag="PB779_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0738445.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(12950..13273)
                     /locus_tag="PB779_000906"
     CDS             complement(12950..13273)
                     /locus_tag="PB779_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738446.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            13402..14565
                     /locus_tag="PB779_000907"
     CDS             13402..14565
                     /locus_tag="PB779_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HDE0738447.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            14635..15984
                     /locus_tag="PB779_000908"
     CDS             14635..15984
                     /locus_tag="PB779_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDE0738448.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(16029..16460)
                     /locus_tag="PB779_000909"
     CDS             complement(16029..16460)
                     /locus_tag="PB779_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0738449.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            16848..19490
                     /gene="alaS"
                     /locus_tag="PB779_000910"
     CDS             16848..19490
                     /gene="alaS"
                     /locus_tag="PB779_000910"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HDE0738450.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKNGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEMAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            19690..20286
                     /locus_tag="PB779_000911"
     CDS             19690..20286
                     /locus_tag="PB779_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDE0738451.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            20408..21556
                     /locus_tag="PB779_000912"
     CDS             20408..21556
                     /locus_tag="PB779_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDE0738452.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(21594..22007)
                     /locus_tag="PB779_000913"
     CDS             complement(21594..22007)
                     /locus_tag="PB779_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HDE0738453.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            22086..22517
                     /locus_tag="PB779_000914"
     CDS             22086..22517
                     /locus_tag="PB779_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HDE0738454.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(22616..22849)
                     /locus_tag="PB779_000915"
     CDS             complement(22616..22849)
                     /locus_tag="PB779_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HDE0738455.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            23032..24702
                     /locus_tag="PB779_000916"
     CDS             23032..24702
                     /locus_tag="PB779_000916"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HDE0738456.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            24849..25235
                     /locus_tag="PB779_000917"
     CDS             24849..25235
                     /locus_tag="PB779_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738457.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            25222..25920
                     /locus_tag="PB779_000918"
     CDS             25222..25920
                     /locus_tag="PB779_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDE0738458.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            25925..26389
                     /locus_tag="PB779_000919"
     CDS             25925..26389
                     /locus_tag="PB779_000919"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HDE0738459.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            26386..27297
                     /locus_tag="PB779_000920"
     CDS             26386..27297
                     /locus_tag="PB779_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDE0738460.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            27532..28071
                     /gene="pyrR"
                     /locus_tag="PB779_000921"
     CDS             27532..28071
                     /gene="pyrR"
                     /locus_tag="PB779_000921"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HDE0738461.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            28085..29368
                     /locus_tag="PB779_000922"
     CDS             28085..29368
                     /locus_tag="PB779_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HDE0738462.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            29381..30307
                     /locus_tag="PB779_000923"
     CDS             29381..30307
                     /locus_tag="PB779_000923"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HDE0738463.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            30326..31606
                     /locus_tag="PB779_000924"
     CDS             30326..31606
                     /locus_tag="PB779_000924"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HDE0738464.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            31611..32687
                     /gene="carA"
                     /locus_tag="PB779_000925"
     CDS             31611..32687
                     /gene="carA"
                     /locus_tag="PB779_000925"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HDE0738465.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            32692..35877
                     /gene="carB"
                     /locus_tag="PB779_000926"
     CDS             32692..35877
                     /gene="carB"
                     /locus_tag="PB779_000926"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HDE0738466.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            35931..36707
                     /locus_tag="PB779_000927"
     CDS             35931..36707
                     /locus_tag="PB779_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HDE0738467.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            36704..37636
                     /locus_tag="PB779_000928"
     CDS             36704..37636
                     /locus_tag="PB779_000928"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HDE0738468.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            37633..38349
                     /gene="pyrF"
                     /locus_tag="PB779_000929"
     CDS             37633..38349
                     /gene="pyrF"
                     /locus_tag="PB779_000929"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HDE0738469.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            38356..38985
                     /locus_tag="PB779_000930"
     CDS             38356..38985
                     /locus_tag="PB779_000930"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HDE0738470.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            38973..39287
                     /locus_tag="PB779_000931"
     CDS             38973..39287
                     /locus_tag="PB779_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738471.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            39325..39966
                     /locus_tag="PB779_000932"
     CDS             39325..39966
                     /locus_tag="PB779_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDE0738472.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            40009..40701
                     /locus_tag="PB779_000933"
     CDS             40009..40701
                     /locus_tag="PB779_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HDE0738473.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            40698..41600
                     /locus_tag="PB779_000934"
     CDS             40698..41600
                     /locus_tag="PB779_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0738474.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(41758..43464)
                     /gene="efbA"
                     /locus_tag="PB779_000935"
     CDS             complement(41758..43464)
                     /gene="efbA"
                     /locus_tag="PB779_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HDE0738475.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
BASE COUNT        13977 a         7689 c         9478 g        12475 t
ORIGIN      
        1 taagaagtgg cactaaataa aagactagtg tgtatttagc cgatttaatt ataaacaagt
       61 aaatggataa agtatatgta atgataaaag aaaaatggat tttctaattt ttaagctaaa
      121 tgttagatca cacatgtata tgctggatag tcttataaaa aatcatgtaa tacagcttgg
      181 tacatgattt ttatttgtag ctgtttttta catagacaca aaaaagaaac cacgcttgta
      241 gacgtggttt cttttttact atctgtttcc agaagctgag gtgctgctgg atggtgtatg
      301 gtcatttgca gcatccgctc cgctagttgc tggctcactg gaagaagcag gaggagcaga
      361 tgaagacggt gtcgagcttt cttcggatga agaagaagga accgttgttg aagacgctgg
      421 ctcgcttgtt tctgctgtcg tgctttcttt tgaggactca gcagttgatt cgctttgact
      481 agtagagcta gagctttgag tcgttgtctc tgttgttgag cttccaggag tctggacata
      541 gctggaagat ggaatagttg ttgatggtgt aattgcattc gatctagctg tatattgatc
      601 tttgtagtac agttcaccgc ccacacgaat taatccgctt ggcatctccc agtctgtatt
      661 tgtcacgtta gctgaaacat actgcataag ctcgcgataa acatcagagg ctacgtgtga
      721 cgattctgaa gtgacaggtg tcattttttt attgtaacct gtccacacgg aaatcgaata
      781 atttggcgta tagcccgcaa ataggatatc tggatacacc ccagaagaaa taccaagttt
      841 tgcatactcg tcatctgtgt aattggatgt tccggtctta ccggcttgat ataacccagc
      901 gatttgcgca ttcgtaccag ttccttcagt gatcgtatct tttaaaatgt ctgtgatcat
      961 ataagctgtt tctggagaca tggctgtttt tccatctggc tcataagttt cttctgttcc
     1021 gtcttggaag acgattttat taacatattg aggtttgtaa taagtccctc cattggcgaa
     1081 agccgcatag gctgctgcca tttttaagga agaagctccg tattttgtcc catcttgttc
     1141 ttccgtatta ctagagatcg cattcgattg atggatcgta ctgtattcga tcccaagatt
     1201 ttttaagaaa gaagccactt tatctgaacc gacttcattg aataatttga ctgctggaac
     1261 attacgggat aagtaaagtg cttggcgtaa agtaatggtg cccatatatt gattatccca
     1321 gtttcctaca ggagtcgaag tcccttcata gttatacggt gcgtcagtaa tagtttttcc
     1381 agtagaatat ttcaaatatt caaaagctgg tccgtaatct gtgacaggtt tcatcgtaga
     1441 accaaaatca cgggaagtat tcactgctaa gttgttgcct aaagttacgt cttctgcgat
     1501 gtgacgtccg ccaatctggg cttttacttt cccggtattg gtgtcgataa gggtggaggc
     1561 aacttgcatc tcgtcgtctg ggtaagagac atactgatcc gtgttgacga tatcatatag
     1621 tttcttttgg gcgtccagat ccaaattcgt ataaatctct aaaccgtctg tgtagacatt
     1681 cttatctgtt ttttcttgta cttcattgat gacttctttg acataattat cgacgatctt
     1741 agtattgtca tcggattgag ttagttcttg cagaccatcc gttaccggta cattaacagc
     1801 ttgatcatat tctgtttgag agattttttc gttttgaagc atcgtataca aaacagtatc
     1861 tcgtcttttc ttcgcctgat ctggataaac ataaggatca taggcggaag gggcttgagg
     1921 catcccagca agcaatgctg tttgcggtaa agaaagttct gataatttct taccaaagta
     1981 catctcagaa gctgtctcca tcccgtacaa gccgtttgac atatacactt tatttacgta
     2041 gtaggtcaag atctcttgtt tcgatttttt ttgttccaat cttacagcca tccacgcttc
     2101 ttgggccttg cgtttcagag tctgatcctc ggcactggtg gagaagaagg aaagtttgat
     2161 caattgctgt gtcaaagtac ttccgccttg cagtccgcca gaggtaaagt tagagagggc
     2221 agaaccgatg atccgaatag ggtcaacccc gatgtgttta taaaaacggc gatcttctac
     2281 cgacacgatc gcatcttcta atgttttcgg taattcattc gcagaaattt tttcacgctt
     2341 ttctgcgcct aaatcttcga atagttcgcc atcttgtgta tatagtttgg aagatacggt
     2401 agcgtctaat tttttatccg tcaattcggg cgcatctttt gcgtaatacc agaaaagtcc
     2461 tacacctgct aaaaagagga tacagaaaaa tgagagtatt cctaaaagga tcttgataaa
     2521 taatcctttt ttatgtgttc cagaggactt tccagaacct ttgccagaat tcttcttcac
     2581 actcttttta ggagtaggct gtttctgtcg tctagagctt ctagtttgtt catttgccat
     2641 tcttgctttc tccttcaata gataatgttg ataaatagaa gtcaaccgcg tccaaataag
     2701 gaatccgcgg agaaatacca gttttgatct ctattcctag ttcttcgatc aaagataaag
     2761 gtagtgattt gcgtcctttt tccttttggg cgtcccagta agcaatcaaa tgaacactat
     2821 tcaaataaaa acagcgcttc aaagacgaaa accataacaa gacaaagcag accccatttt
     2881 gttcgaggca tgctttcata tgttcgattt gatgggcatg gaagttttta aagggaaaag
     2941 atgttttgtt cttggtttct tttgcttcaa agtccaagta aaagcctcga tagacgccat
     3001 tatagtctgt agttgaggct tgggtaaagt aggcttcctt gatcacagca gcacttctct
     3061 taggatagtc tactttcacg atttggatag gggtaggctt tttatggata accgccaacc
     3121 cgcgggaaag ataatattta ttactttcat tgattgcttc ttcaaagcgc atcccccgat
     3181 tgccgaattc agtgatctga tttctttttt cttgaatttt ttcgacggga gaggcattct
     3241 tataataagg ttggccattt ggatagcgca ataccatctt taatcacact cctaggccac
     3301 attatagcaa aaaagcggat agaaagaaaa ggaatctgag atggataagt caaaagtaat
     3361 ctatgtgtct gggtatcgaa gtttcgaact cggtgttttt aaagaaaatg atcctaaaat
     3421 ccaagttgtt aaaaatgttt taaaaaaaga actccatcag ttagcagaag aagggctgga
     3481 atgggtactt gtcagtggga atttgggcgt cgaactatgg gctgtgcaaa tagtagcgga
     3541 attgaaagaa gaatatccgg aactatctct tggtattttg tatccttttt ctgattttgg
     3601 taataactgg aatgaaggga accaagaaaa aaaacaatta gcagaacaat tagcagatta
     3661 tgtcgaagct gttagccatc aaccctacca atcacctagt cagctaaaga atcacactcg
     3721 ttttatactt gagcatacag tgggctgtct gctgatctat gatgaagaat tccctggaaa
     3781 aacgaagtat ttttttgaag atgcacagaa ttaccaagca gatcatccct acgaaattcg
     3841 gctgatcagt atggacgatc ttcaaaattt tagtgaataa tcgatattgt gtttgattta
     3901 tcaacttttt tcctatacaa tgaaaaaggt agaaatgtta ttacgtaaat gaaaactaga
     3961 ggtgtaaata tggcgaattt ggtttatagt cctaaagaca ttttacaaca agaattcaaa
     4021 acaaaaatgc gcggctatga tcccgttgaa gttgatgaat tcttagacaa tatcatcaaa
     4081 gattatgaaa cttacagcaa agaactcctt gctttacaag aagaaaacga tcgattgagt
     4141 gcaaaagtag ctcaattatc taaaactcaa ggagcagctc aaacacgcgt gcaacaaaca
     4201 gaggcaccaa agagcgcagc agtgaccaat tttgatatct taaaacgctt gtcaaatctt
     4261 gaacgtgaag tatttggtaa aaagcttgat caacaagcaa gtgcagtcaa accagcacaa
     4321 cctaatccaa ataactacac aaatgcagac acaagcttag atgataatga aaaaacacgt
     4381 caattttaat ttttgattaa tgaatttgcg gttttcgggt aatcgcggtc tgacttgatc
     4441 aggctgagga aagtccatgc tcgcacaggc tgtgatgcct gtagtgttcg tgcttagcga
     4501 aaccataagc taaggtactc tttggagtaa cggcaggaaa acaagctaag gcttcggcta
     4561 tgcttaagta tccttgaaag tgccacagtg acgaagcggc tggggaaacc catccggtgg
     4621 aacgcggtaa acccctcgag cgagcaaccc aaacaatggt aggggcgctt tttgtctgga
     4681 agaagaacag gacaaaaagg cagtataact gcagatagat ggttaccgct ttgttttttc
     4741 tccctggaaa agcaaagtac agaacatggc ttatagaaaa ccgcaaacat cagggaatta
     4801 ggtcgtgaca aaagtaatgc gttataagaa acaagaaaaa catttgaaag ctatttttca
     4861 atacttcaga tgaatcgttc ttattacaaa acaaactttt gtatcaccgg ttattcggaa
     4921 tttgagtaaa agtgtggggt aggactgatg tcccacctcc tttttttata aataaggaga
     4981 ttgtgtatgg aaaaaaacag gaagttcaac ctcgtcgcaa ctgcggcaag cgggctagaa
     5041 gcactggttg gtaaagaatt aagagatctt ggaatcgaat gccaagttga gaacggacgt
     5101 gcacgttttg aaggaacaat ggaaacgatc gctacagcta atttatggtt acgtacagca
     5161 gatcgagtaa aaatcgtggt tggggaattc gatgcgtata cgtttgatga attgtttgaa
     5221 aacgtaaaag cattgccttg ggaagatttt cttccactag atgcagcttt tcctgtagct
     5281 ggaaaatcga tcaagtcgaa actatatagc acacctgatt gccaagcgat cacaaaaaaa
     5341 gcaatcgttg aacgtctccg tacctattat caccgtccag cttctgtacc actgacggaa
     5401 actggcgcac attttcagtt ggaagtagct ttgctgaaag accatgtgat ggtaactctg
     5461 gatacgacag gaccaagttt attcaaacgt ggttatcgct tagaaaaagg tggagcacca
     5521 ttgaaagaaa acatggcagc agcacttatt atgttgacaa attggcgaaa agaccgtcca
     5581 ttttatgatc ctgtatgtgg ttcaggtacg ctttgtattg aagcagcctt aataggccat
     5641 aatatcgcac caggattcaa tcgtgagttt gcttgcgaat cttgggattg gttcagtcaa
     5701 gaaatcatgg aaaatgttcg atcagcagcc gaagaaaaag cagattatga tattgaatta
     5761 gatattactg gttcagatat caatggacgg atgattgaaa ttgccaaagc caatgcagaa
     5821 gaaatcggat taggctcttc gattaccttt aagcaacaag cagtcaaaga cttcaaaacg
     5881 gataaagaat acggggtcat cgtggctaat ccgccttacg gagaacgtct aggagaagaa
     5941 gaaactgttc ggaaattata taaagaaatg ggcgatgtat tccgtccatt aaaaacatgg
     6001 agtaaatata tcttgactag cgacttagcg tttgaggaat tttacggaca aaaagcaacc
     6061 aaaaaaagaa aattgtacaa tggtgcattg cgtacggatc tattccagta ttggggaact
     6121 cgtccgccta gaaaaaaaga gaaagacgaa taatcttact aattgattca ttcaattgga
     6181 tgtttggagg aatagggaat gaaagaaaaa gagtttttac aagaagtaaa agaaatcaat
     6241 cttctacaac aagctttagg aatcctcgat tgggatacac aaacaggtat gcctgaaaaa
     6301 gctagtgcat accgaagtga agtagacagc tatctttaca gcatttattt ttcaaaaaaa
     6361 atcggtccaa aaatcaaaga agccattcgc tatttttctg aacatccgga agaattgtcg
     6421 gaagttggaa ctgccgtttt tgccaaagta aaagaagagt atgatttgga acatcgcgta
     6481 ccggaagatc ttatgagaaa atatacagct gccgtttctt cagcacacgg acaatggcaa
     6541 aaagctagag aaacacaaca attttctgat tttcaacacg cattgaatca aaatattgaa
     6601 ttaacaaaac agttgatacc ttactggaga aaagatgaaa agacgaatta tgatgttttg
     6661 ctgaatcaat acgaacccgg gatgactgtc gaaatccttg ataaggtatt tgatcagctt
     6721 aaagaaggaa ttctttcgat ccgccgtacg ctccaagaaa aagggactga acctgaaaca
     6781 gactttttaa atcggagaat gacgaaaaaa caacagaaga gatttgtagt gaaagtaatc
     6841 gaacaacttg gttatgattt tagtcgtggt cgtttagatg acactgtcca cccatttatg
     6901 actggaatta atccgaatga tgcacgaatc acgacacgat ggaacgaaac agatttcaaa
     6961 atggctgttt ttggagtgat ccacgaggct ggtcatggta tgtatgaaca agacatcgat
     7021 gataaatatg cgtatacacc ggtttatgaa ggtacatcaa tgggtatcca tgaatcacaa
     7081 tcgttgttta acgagatcat tattggaagt agtcgcagct tctggaaaaa gcaatatcct
     7141 ttctttcaag aatgtgcaga aggaacattc gatgatattc cttttgacaa attttatcgt
     7201 tcattgaacc atacaaaatc aagtttggtt cgtatcgagg cagacagttt gacttaccct
     7261 ctccatatca tcattcgtta tgaaatcgaa aaaatgattt tcaatgaagg ggtagatgtt
     7321 gctgaactac ctgaaatatg gaatcaaaaa tatgaagagt atctgggaat acgaccaaca
     7381 aatgatgtgg aaggcatcct acaagacgtt cattggtcag gtgcaagctt tggttatttt
     7441 ccctcttatg cattagggta catgtatgcg gcacaattac ttcattcttt gcagcaagaa
     7501 atagatgtgg aaaatgttct agcgtcagac gattattctc caatcaaaaa ctggatgtca
     7561 gagcatatcc atcaatatgg tgcatctaga aaaccaaatc aattaatcat ggatgcaaca
     7621 catgaaccgc ttaatccgca atacctgatc gactatatga aagacctgta ttttaatgta
     7681 tatcaggtaa aataaaatac aatttacaaa gatagctgaa attcatctaa tctatagatg
     7741 ttttcagcta tttacttaag aaagaagtgg aacgaatgga taaattacaa gtgatcgctg
     7801 attatagtat ggaccaatta gcgcatgatc aaacaggaca tgggagcgat cataccaaaa
     7861 gagttgtcaa gttagctgaa aaaattttgg agacggaacc gcaggcagac cgctttgtga
     7921 cgcttgcagc agcttaccta catgatacga ttgatgataa agtcgttaaa aatgagaacg
     7981 aggcaaagca acagcttcgt gtattccttc gctctttgcc aatagtagag gaacagatct
     8041 cgatgatttt ttccattatc gaaaatatgt ccttttctaa aaatctctct gaagcggccg
     8101 aactatctct ggaaggtaag atcgttcaag acgctgatcg tatcgaagca ttaggagcaa
     8161 tcggcatttt gcgtactgct tatttcggcg gtggacatgg gcacccgatt tttgatcctg
     8221 aactgtatcc gcaaacattc aaggacaaag aaaattaccg aaaaggcacg acagtgatca
     8281 atcattttta tgaaaaactg ttcttgctgt ctgataaaat gaatactgat tacggatatg
     8341 aagaagccaa acgaagagaa accttcatgc gtgaattctt agaagaattt tttctggaat
     8401 ggtctattga cgatgaaaat tttactccag acaattggat caaaaataac aaaaaatgat
     8461 ggaggttgtg acagaagtgg tcagctccaa gatatttcgg atcattttcc gtaaaagtta
     8521 cttctggaac actgtttacc aagaggtcgt gagcctgccg ttcagctccg agtcacaagg
     8581 aacaatttca aaaaatagct tctcgtgttt gatgaatatt gtaacttgtg attcggaatt
     8641 ggcaggagaa caccgtttat tcggaagaat aggactgtga caagactttt gtcacagtcc
     8701 ttttttcgaa ttcaacaagt aaaactttta agaaatattc agagagtaaa attaaaaatt
     8761 gctgataaac gaagatggaa attttatgta tttttattgg tctatgcaat aaataaatta
     8821 aatattcaga atacaattga ttttaacgaa agggcttcta tcaatggttg tgttgtattt
     8881 atctgcccag gtagagtaaa atagatcatt atctaaaagg taattgttca tactatataa
     8941 gtcatttgaa agtaaaaaga tactgtaaat aaaaaatgtg gttaaataat tctcataatc
     9001 agtgtaagcg ttatcaaaaa tatagcatac ttgctttgta gatgaatgac acgatatatg
     9061 tttggtatgt tctgcaagac agatgaatat ggaggtggag acaatgtctt ccaaagaact
     9121 aacaatgtat ttagagaaag aattggatca actgaaagaa aaggggttat acaatacgat
     9181 cgacatacta gaaagtgaaa atggtgcttg tatcatcgta gacggaaaaa agatgatcaa
     9241 tctagcatcc aacaattatc ttggatttgc caatcgcgaa gaattgaaaa aagcatgtat
     9301 tgaagcaacc gaaacttatg gtgtaggagc aggagcagtc cgaacgatca atggttcgct
     9361 gaaaatccat cagcaattag aagaaaaaat cgcagaattc aaagggacag aagcagcaat
     9421 cgcctttcaa tctggattca actgcaatat gggcgctatc tctgcagtaa tgacaaaaga
     9481 agatgctatc ttatcggatg aattaaacca tgcatctatt attgacggtt gccgcttatc
     9541 cggagcaaaa atcatccgaa ttaaacatca agatatgaaa gaccttgaga aaaaagcaaa
     9601 ggaagcgata gaaagtaaga aatataaaaa aatcatgtat atcacagatg gtgttttctc
     9661 catggatgga gacattgcac gattgccgga aattattccg attgttgaaa aatatggact
     9721 gatcacctac gtcgatgatg cgcacggctc aggcgtaact ggaaaaggtg caggaaccgt
     9781 caagcatttt ggattaagcg acaaaatcga tatgcaaatg ggcacgttat cgaaagctat
     9841 aggtgttgtt gggggttatg tagctggatc gaaaacacta atcgactggt tgaaagctag
     9901 aagtcggcca ttcctatttt ctacttcgct aactccaggt gcagctgcag ctgcattggc
     9961 ttcgattact ttgatgcaag aacatccgga acttgtcgaa aaagtttggg aaaatgctaa
    10021 ttattttaaa gaagaattga aaaaagtagg ctataacatc ggtatgtctg aaacacctat
    10081 tactccagtc attttgggag acgaaaaagt gactcagact ttctctaaga agctgatcga
    10141 acatgggatt tatgctaaac caatcgttta tccaactgtg cctcttggga caggcaggat
    10201 cagaaatatg ccgactgcgg aacatacgag ggaaatgctt gatgaagcag tagcagttta
    10261 tcaaaaaata ggaaaagaaa tggaaattat ttaactaaat ttagtttttt cgtctattta
    10321 aaattagaga acatgttcac gcatatattg ttaatcatct gaagatagta gtaaaaaaga
    10381 tcagggagga tcatcatgaa aaaagtattg gtgacaggat gtttaggaca aattggttca
    10441 gagttgatca cacggctacg tcaagaacta ggcagtgaaa atgtcattgc gacagatata
    10501 cgcatgcctg aagtcattga gaaaaacgat atctttgaga tcctagatgt aatggattac
    10561 gaaaaaatgc gcagcatagc agaacaatat caagtggaca cattgattca tttggctgct
    10621 cttttgtcag ctgttgcaga agcaaaacca caattagcct ggaatttgaa cgtgactggg
    10681 ctggtcaatg cattggaagt cgctagagaa ttccagctga aattttttac gccaagttca
    10741 atcggcgcgt ttggtccaaa tactccaaaa gatcataccc cacaagatac tcttcagcgt
    10801 cctacaacca tgtatggggt aacgaaggta gctggagaac tactatgtga ttattattat
    10861 gtgaaatatg gcgtagatac tcgtggtgtc cgtttccctg gattgatttc ttatgcaacc
    10921 ttgccaggag gcggtacgac agactacgca gtcgatattt attattcagc aatcaaagaa
    10981 ggaaagtaca ctagtttcat tgatcaaggt acatcaatgg atatgatgta tatgccagat
    11041 gcgatcgatg ccattataaa actcatgaat gcagatcctg atcgattggt tcatcgaaat
    11101 gccttcaata tatcggcgat gtcttttgac ccggaagaga tcaaagcatc tattcaaaaa
    11161 atcataccag attttgaaat ggattatgat gtggatcctg tacgtcagtc aatagcagaa
    11221 tcttggccaa attcactaga tgtttcttgt gcgcaagagg aatggggctt ttcgccgaaa
    11281 tacgacttag atgtgatgac aaaggatatg ttggaaaaac tgaaagaaaa attggtagag
    11341 acggtataaa acaagaacca catccaaaaa gttttttata cttttgggat tggctatggt
    11401 atgaaagggg acaagggatg gaagaatatc aagccacgcc agtaaaagaa gtaaaaatag
    11461 aaaatgaatt aaaacgtacg atgggatttt ttactgcttt atcgactgtt atgggcacag
    11521 tgatcggtgc aggggtattt tttaaagccg caagcgtagc agaagttaca ggatccgcca
    11581 gtttgcatat gttttcttgg tttctcggtg gtatgatttc tgtctgtgca ggactaacag
    11641 gagctgaact ggcagctgct attccagaaa caggagggat gattaaatat atcgaacgga
    11701 tttacggaaa tacagcagct tttttattgg gctgggcgca agtcgtgatt tattttccag
    11761 caaatgtagc agccttgtcg atcattttcg gtacacagtt cgtcaatcta tttggtcttt
    11821 cccagtcaat gattgttccc gtagctgtta cagctgctgt atcgatcctg ttgatcaatt
    11881 ttttaggttc taaagctgga ggggcttttc agtcgattac gcttgtctgc aagcttattc
    11941 ctttgtttgt gatcgtcatt ttcggtttgt tccgacaaga aggagtagac ttccaactgt
    12001 ttccgatcca agcaggagaa aatctttcat ttttctcagc cttgggagcg ggcttgctag
    12061 caacgatgtt cgcatacgac ggttggatac acgtaggaaa tatttcggga gaattgaaaa
    12121 agccggcgaa agatttgcca aaagcaattt ctttaggaat catcggaatc atgatcgttt
    12181 atttattagt aaatgcggtg ttcttaagaa ccgcatctat cgacggagtc gcaggaaaca
    12241 gcaatgcggc aagtgacgtt gcaaaaatga tttttggcgg cttcggtgga agactggtca
    12301 cagttggtat cttgatttct gtttatggaa ccatcaatgg ctataccctt actggaatgc
    12361 gtctccctta tgttatggca aaagaaaaca acctgccttt tagcaagctc tttgctaaac
    12421 ttcatgataa aactaaagtt cctgtagccg caggtatctt agagctagtc atcgctattg
    12481 gcatgatgat gatcggtggt tttgatacac taacggatat gctgatcttt gtcatttgga
    12541 ttttttatac gatggtcttt gttggtgtca ttcttcttcg taaaaaagaa cctgatttgt
    12601 ttcgaccata caaagttcca atgtatccgt ttattccact agtagcaatc attggaggga
    12661 cttttatcgt atcaagcacg cttatcactc agaccttttt agcttcgatg gggatagtat
    12721 tgacacttgc tggtatcccg atttatctct atttaaaacg tagatagcta aaacattcga
    12781 attttattag aactgcactt ctctgccaaa caaaatattt tatttaaatg aggagtacgt
    12841 ggaagaaatg tcaaaagtac tcgttaattt tgatcacgta aatgtcgttt tgtctacgat
    12901 gaaatagcaa agtaaaagac agaaatcggg ctcaaccgat ttctgtcttt tactttgatt
    12961 tgcgtaactg aactattcgg cgtacgccgc gataaatatt taataaaacc aagcaaccag
    13021 aaatgaaaat gggaagccaa atcagataga cagggtagcc aagcacttta gacaaagcat
    13081 gtggagtcat tttatccatt tcaagaagtg cttgctgcca agtctgaaga ttgaagacta
    13141 gcatgaaacc cgaaataatc aggagaataa atcctaaata atgaattgta gttctttttc
    13201 ttacataagc gatcgtagca taaaggaaca gtaaaaaaat aggtacgcca aaaacaaagt
    13261 acatattcag catctcgaca ccccctttgt gtttatctta ctttactttg aaagaaatga
    13321 gaaataatag cctcgttact tgcttgaaac agcaaaggac tgctaagata agagagatac
    13381 aaagaatcaa ggaggagtca tatggcaagt tatatcgaac cgattcgttt tgcgctgatt
    13441 gtttttccat ttttagcctt agcgatctca tctgtttttt ttatttatga atatcgaaag
    13501 tatggaacat ttctagtaac aagggcagtt attttgtatt ctttcgtttt ttatttattg
    13561 tgtgcgtatt ttttggtgat cttaccactt ccggcaaagg agacggttgc ccaaatgaca
    13621 gggccaaaga tggagctgca tttatttgct tcatggcaac atttcagaga caacacggta
    13681 ttggtcttgt ctgaacctag tacctacctg ccggcaatga agcagagtgt atttttggaa
    13741 ccagctttta atgttttatt actcatacca tttggcattt atttaagata ttatttccgg
    13801 ctttctttta tgaaaacgat gattgctagt ttctgccttt ctctattttt tgaattgacg
    13861 cagctaagtg gactttattt tatctaccca agaccatacc gcttatttga tgtgaatgat
    13921 ttagtgacaa atacattggg tggaatcatt ggttttgtcg ttacgccgtt atttacattt
    13981 atgcttccta caagaagacg aatggatgaa ctttcttatg aaaaaggaaa gactgtctca
    14041 ttgactcgac gcttggtcgc ttatttgatc gactggacat ttttatctct tattaatttg
    14101 gtagcggcga ttttctttaa aattgcgttc gattcagggg cagttacttc tcatatctgg
    14161 tggcttttat tagaagtagg ggtatacttt atgattgtac cgtttataac caatggatgg
    14221 acacttggca aaaaaattgt gcgtatccgt ttggtggaag aagaccgcga acgaatttct
    14281 ttaaaagcat tgatgatccg ctacgggtat ctgtactttc ttttttatgg tttaagctgg
    14341 ttggggcagt tgcttcagca aatcatgaat tcgacaacga atacggtgtt gcagatgagt
    14401 gcagtattca tttctctcgg tgtcttgtta ctacaaggta tttttatttt aaatatcttg
    14461 ctatcatttt tgagaaaaaa acggattctg ttttatgaaa aagctagtca cacatatact
    14521 gttagcacga ttggccaaac aaaggatgat gattctcgaa attagctgag caaaaacgct
    14581 ttgtctgtgt tataatgcca aagtcgtgat aatttaaaga gaagaggtgc acgaatgaat
    14641 aattttgata tattccgctt caaaccgttt atcaatgaag cgttaaccgc aaagggcttc
    14701 aaacagccca cagaggtcca ggaacgtttg attcctttaa ttgcaaaagg aaaaaatatc
    14761 attgggcaat ctcaaactgg tacaggaaaa acacatacgt ttttgttgcc tttgtttgaa
    14821 aaaatcaatg cagaaaaaga ggaagtacaa gttgttatta cagctccaag tagggaacta
    14881 gctgcacaga tctatgaagc agctacacaa atcgctaaat tttctacacc ggagatccgt
    14941 gtctcgaatt ttgtcggcgg tacagacaaa cagcgtcaat taaatcgtct gcatcaccaa
    15001 cagccacagg ttgtagtagg cacgcctggt agaatattag acatgatgaa tgaacaagcg
    15061 ctgaagattc acaccgcatt tgcatttgtt gtcgatgaag cggatatgac attggatatg
    15121 ggttttttaa atgaagtaga ccaaattgca agtcgattac cagaaaagct gcagttttta
    15181 gttttttctg ccactattcc agaaaaactt cgtccattct tacgaaaata catggaaaat
    15241 ccaatcattg aagaaatcaa accaaaagca gttatttctg aagacattga aaattggctg
    15301 atttcaacaa aaggtaaaga tgagaatcaa atgatttatc aactgctgac aattggtcat
    15361 ccttatttag caatcgtatt tgccaataca aaacagcatg tggatgaaat tgccgattac
    15421 ttgaaaaacc aaggcttgaa agtagcaaag attcatggag acatcacccc aagagagaga
    15481 aaacgagtga tgcgacaagt acagaatctg gagtatcaat atgttgtagc gactgattta
    15541 gctgctagag ggatcgatat cgaaggtgtc tctcatgtta ttaatgcaga aattccagaa
    15601 gatctagact tctttatcca tcgtgtcgga cgtactggac gtaatggctt aaaaggaacg
    15661 gccattacgt tatattcgcc aaatgatgag caagccattg atgcgataga aaaattgggc
    15721 gtctcatttg aaccaaaaga aatcaaaaac ggggaaatcg tcaaaacata cgatcgtaat
    15781 agacgtgcca aacgagaaaa atcaaaagat gtattagatc ccacgctgat tggtcttgtg
    15841 aagaagaaaa agaaaaagat caagcctggt tataagaaaa aaatcgattg ggcaattgca
    15901 gaaaaaaata aaaaagaacg caaaatcgaa cgcagacagc aaagccgtac tgctcgtaaa
    15961 aataagaaaa attcacataa ataaaaaaca agaggttgtg acaaaaggcg tgtcacaatc
    16021 tcttgttttt aagctagact ttttttcatt ccgatacaaa gtacttcatc ttcaataaaa
    16081 ggttctgtgc aagtatgata cccttgtttt tcataaaaat ctacagccgt catttcagct
    16141 actacataac tagtctgaca accttctgaa accgcccgtt tttcagcagc ttcaagcaac
    16201 tgaccgccta acccttttcc tcggtattct tttgctacgc aaaatcgttc cggcttgaag
    16261 caagtaggtg ttttcttttc ataacgcaaa gtagctactg gtcttttttg atcaagaaat
    16321 agataatagg tttgttgcgg gatatctttt ccgtcgaatt ctagttctgc aggaatccct
    16381 tgttctaata caaaaacttg atatctcaaa aagcagctag ctgcgcgtat ccattcatcc
    16441 gctccaacta tttttttcat catattcctc cttgtcatga atagcagaga tgtattgatt
    16501 cctttattct tatcgtacca aaaatcgtgg agtatgacca aaaggaaatg aaaataaaaa
    16561 ttgagatatt gacagtgatc aatagaatgc gtatactaat taagtacgaa aaggatatga
    16621 tttgtttttt aagactcaca gaaaattctt tcttggctga aaaaagaata gtcactaatc
    16681 aaattgctcc ctttttctat tttggtagaa ataccgacgc agctcagcgt tatcgagttt
    16741 aagaggtaat gattacacat cattgcaatc aaggtggtac cgcgagtttt cgtccttggc
    16801 tgtgatggtg tttttttgta tttaatttat agaaagcagg taatgacatg aaacaattaa
    16861 gtagtgcaca agttcgacaa atgtttcttg atttcttcca atctaaagga catacgattg
    16921 aacctagtgc gtctttgatc cccgtgaacg atccaacctt attgtggatc aactctggtg
    16981 ttgcaacatt gaaaaaatat tttgatggtt cagttgtgcc agaaaatcca agaatcacaa
    17041 atgcccaaaa atctattcga acaaatgata tcgaaaatgt cggtaaaaca gcacggcacc
    17101 atacgatgtt tgagatgctg ggtaattttt cgattggtga ctatttcaaa aatgaagcca
    17161 tccactgggc atgggaattt ttgactgatc caaaatggat ggcattcgat ccagaaaaac
    17221 tttatgtaac agtttatcca aaagatacag aagcaaaacg catctggcat gaagaagttg
    17281 gcctgccact agatcacatt attgatgtag aagacaactt ctgggatatc ggtgcaggcc
    17341 catgtggtcc ggatacggaa attttctatg accgtggaga agcttataac gatttagcag
    17401 aagacgatcc tgaaaactat ccaggaggag aaaatgaacg ttatttagaa atctggaact
    17461 tagtattttc agaattcaac cataagcctg ataacacatt tgaaccactt cctcataaaa
    17521 acattgatac ggggatggga ttggaacgca tggtctcaat cgttcaagat gcgtcaacga
    17581 actttgagac agacttgttt atgcctatta tccacgccgt agaaaagcta agcaaacaag
    17641 taaaaaatgg tgaaaaccca gtaacagata tttcttacaa agtaatcgca gatcatattc
    17701 gcgccctttc atttgctatt ggcgacggtg cattgccatc gaatgaaggg agagggtatg
    17761 tcttacgccg tttgcttcgt cgtgctgtca tgcatgggaa aaaattaggt attgaacaag
    17821 cattcttata tcgtttagtc cctgttgttg gggaaatcat ggtaagttat tatcctgaag
    17881 tacttcaaca aaaagaattt attgaaaaag ttatccgtac agaagaagaa cgtttcaatg
    17941 aaacaatcaa tgaaggtttg gaaatcttaa atcaagtgat ccaagaagta aaaaacgaaa
    18001 acgggacgac tctagcagga aaagacatct tcaaactata cgacacatat ggcttcccgg
    18061 tagaattaac ggaagagatg gcagaagatg aaggactgaa agttgatcat gctggttttg
    18121 aaaaagaaat ggatgcacaa cgcgaacgtg ctcgctctgc ccgcagtact gaaaaatcaa
    18181 tgggggtaca atctgcttta ttgacagata tcaaagtaga aagtaaattc attggataca
    18241 cagaacaaga atcagatagt caattattgg tcatcgttaa aggtgagtct cttttgaatg
    18301 aagtcgcaga aggtgaagct caaatgatct ttgatcaaac acctttctat gcagaaatgg
    18361 gtgggcaagt agcggatcaa ggatggatca tgaatgaagt aggcgaaatc gtagcagttg
    18421 ttacagatgt tcaaaaagcg cctaatggtc aatttatgca caccgtagaa gtaaaagcac
    18481 caatgagtga aggacaaacc tatcatctat tgatcgatca atcgatgcgc aatcggatca
    18541 tcaaaaacca tacagcaacc catctactgc acaaggcatt gaaagaagta cttggcgagc
    18601 atgcaaatca agctggttct ttagtcgctc ctggacattt acgattcgac tttacccact
    18661 ttggtcaaat cacttcagat gaattagctg aaatggaaag aatcgtcaac gaaaaaatct
    18721 gggaagctat cccagttgaa acaattgaaa cagatatcga tacagccaaa aacatgggtg
    18781 caatggcttt gtttggtgaa aaatacggac atgacgttcg agtagtaaat attggcggct
    18841 ggtcaatcga actgtgcgga ggcacacatg tagcaaatac agaaaacatc ggaatcttca
    18901 aaatcgtttc tgaatcagga attggtgcag gcgtgcgacg aatcgaggct gtaacaagta
    18961 aagaagcgta cgaactactt gaagaagaag aaaaacaact aaaacaagta gcaacaattg
    19021 ttaaatcacc tcaattgaaa gaagttgttt caaaagcgga acaattgcaa cagcaagtaa
    19081 gagagctaca aaaggaaaat gaacaattag ctagcaagtt agcgaatcaa caagctggtg
    19141 atgtattcaa agatccagaa acgatcaatg gaaaaacaat cattgcagca caagtaaaag
    19201 tgaaagatat gaatcagctg cgtcaattag ctgaccaatg gaaacaaaaa aatatttcag
    19261 atattcttgt tttagcaaac gaacaagaag gaaaagtcag tctgctagcg gcaatgacga
    19321 aagaatcaaa tgaagctgga ctaaaagctg gcgacttgat taaagcaatc gcaccgaaag
    19381 taggcggtgg cggtggtgga cgtccagaca tggcacaagc tggcgggaaa aatcctgctg
    19441 gtattccaga tgcacttaaa gctgcgaaag aatgggttgc gcaacaatag ggcgtttacg
    19501 tttgacagaa aaacaaaagt tcaaacattg aacgaaacat gattatgggg gcgaagacaa
    19561 acaagtcttg ccctcatact tttttcaatt ggatggcgca tctaatcaaa tggtcggatt
    19621 cggatggtct ttagttgacg aaagtgacag aaatttttac gattagtata aataaaaagg
    19681 ggtgaaaaaa tgaatagtag aaataagacc tttcgactag tcttacgtgc gatcttgtta
    19741 gcaatcatca tcgtacaagc gatggttcct tggctggggt ttattccatt aggattcatt
    19801 agtttaacaa ttatccatat cacagtaatt attgctgcag tagtattagg cccaaaagat
    19861 ggcatggtga ttggcttgtt ttggggaatc gctacaattg ttcgtgccta tgccatgcca
    19921 acaacgccat ttgatacatt agtgttcacg aatccgatta tctcggtagt tcccagagta
    19981 cttgttggct tagtagcagg cttggttttc cactggattt atcaaaaaaa taaatcaata
    20041 acgatcagct cagcctttgc aggggtactg ggttcattgg tcaatacagt cttagtgtta
    20101 ggattcatgg gattatttta tacaggtgca acggcagatg cctatggtgt agactctgct
    20161 cttttattta aaaccttagc aggggttgca gcaatcaatg ggataccaga agcaataggt
    20221 gcgggaatca taacaccatt actagcaaaa gcgttatttg cagcaacacc gttgaaacca
    20281 gaataatgac catcttttaa tagtaatagg acgcacgata gatagaaaaa ggaagagagg
    20341 agaggaaaac aatcgtcctc tccatctttt tacctgagca acaagcaaac tagaaggggt
    20401 aaaaaacttg gctaagaaac aagaagaaaa aaagaaacaa ataccgcaac agcggacaaa
    20461 aaaaggagta ctagcgggta tcttaggatt ggttacgaat ctgatcttgt ttgtctctaa
    20521 gctaatgatc gggctttttt caggaagtgt ctccattatg gctgatgcag tgaacagtct
    20581 atcagatact gcttcatcca tattgacttt gatcggattt aaaattgctg caaagccagc
    20641 agatcaggaa catccttatg gacacgaacg cttcgaatat atcagtgggt tatttgtttc
    20701 gatcatcatt acttatgtag gatttcaatt tttagagtct tctgctgaaa aaatcatcca
    20761 tccagaaaat gtctctttaa cacccatcgt cttttttgtc ctaatcattt ccatcttttt
    20821 gaaatttgca caaggcaaaa tgtatcaggt tattgcgcaa tccattgatt ctgaaacatt
    20881 gagagctaca gcaacagata gttataatga tgtctttact acactggctg tattgctttc
    20941 agcagcaatc gaatgggtaa ctggatggcg tattgatgga tatataggtt ttgctttagc
    21001 attatatatc ctttatagtg gattgacgat gcttcgaaat tttgtatacg aactattagg
    21061 aagtcgccca acgccagcag agattgaaga aatggaagag catttaaatg cttgcgatga
    21121 tatacttggc tatcatgatt tattggtgca taactatgga cccaataaac gctttgcatc
    21181 agtccacatc gaagtagatg aatcaatgaa tttgaatgtg gctcataaga ttattgatct
    21241 gatagaaaaa gactttaaaa agtctttgga tgtggaactt gtctgtcact tggatccaat
    21301 gcctgttgat aacgaaaaat actataatat cttgcggcag ttaaagcaaa ttcttcttga
    21361 aacaggtaca gggcttaata ttcatgattt tagagtaatt catcaaggaa aaacactgca
    21421 atttgatgta gtggtccctg agaaattcca gtttgttgat acagaactag aaagaatctt
    21481 acgtagtcaa atagaagaaa aaatcggaga ttaccaattg gaaattacgt ttgatcacaa
    21541 ttatctttta tattaaatga gaaactataa aaagactcct taaagttttt aatttaaaga
    21601 gtcttttttt cttttaattg tttatggaga gcctgacgtg caagattatc tgctccttta
    21661 tttttgtttt cgggcaacca ttgcaggatc aataaagaaa attcggatag aagttcttgg
    21721 attctttgaa ggtagggaag gaagagctcg ttcttcgttg cgtttttgtc gaccgtagaa
    21781 actagtgttt tgctgtctga aaaacagaaa atcgtttcat tctgtaagtc gtttttcttt
    21841 agaaattcta aagtttttaa aaagacttcg aactctgctt gatggtttgt ccctatagaa
    21901 agcgggatag atagctgttc ttgtttacct tgatagacaa tcaagattcc acctccacta
    21961 ggaccagggt tgccttttgt agaggcatca atgtatactt ttaacataaa aagagattct
    22021 cctttttgtt caaactaatg ttatggtaag attatatcat tactgaatcg gtgagaggtt
    22081 agagaatgaa aaaaaatatt cgatggcagc ctgaactggc acatacgatc atctattggt
    22141 cattgacctt gatcattctg ttttttagtc tgattctttc tttagaaaac acaggtcctt
    22201 attggaaaag caattttgtt ttaggtattt ttcttgtttt tctatttcta ggtttgcggc
    22261 gttcttttat tttaaaatca aactctgtga ttatacgtta tgctgctttt tggaaagacc
    22321 gagaaatatc tgtcggacag attcgatctt tgacgccaac taatactggg gtgcaaatga
    22381 tgttgcaaga tgagaaagcc ccatctgttt tcatgatgcg aaaaaaagat caagtagtcc
    22441 tttttgatca ttttgaaaaa aacggaccca aatcagaatc aattccttat ccttatacga
    22501 aaaaaagaaa aagctaattt taaaaatcag aacctaaaaa aacgaatttt tacaggaaaa
    22561 gaaaagagtg agacgtacgg ttcatcccgt ttagcgtctc actctatttg tttatctatt
    22621 catgcatact agtatcggta gtctgaacgt tgcctttctt gacatgggca gcttgtgttc
    22681 ctcgattccc ttcgatgatc tcaaattcga ccacttgatt ttcttccaaa gttttgaatc
    22741 cctcttcttc aatcgcagta aaatgtacaa aaatttcttc tgtgtcatca taactgataa
    22801 agccgtatcc ttttttgttg tcaaaccatt ttacaattcc tgtggtcaaa gcactcacga
    22861 cctttctaaa gtctgatcat agccttcatt ataaagagta tttataagta cgtcaaataa
    22921 attaaaaacc tgtaatttta tgtttttttt ctgaataaaa aaaggtataa ttggcatatc
    22981 ttaacaaaga agatattttg ttgaataaag ttcgtgaaaa ggggtaatca aatgaagaat
    23041 gatctgcaaa tttcacaaga aacagagcta gaaccgattg ttgaagtggc tagtaaatta
    23101 gatcttaagg aagacgattt ggaactgtat gggaaatata aggcgaaaat caatttttct
    23161 ggaatcaatc gatcaaagga taacgctgag gggcatttga tcttagttac ttccatcaat
    23221 ccaacaccag ctggcgaagg aaagtcaacg atcactgtag ggttaggaga cgcgctcaat
    23281 aaaatcaata aaaaatctgt tattgcattg cgagaaccct cacttggtcc tgtgatggga
    23341 atcaaaggtg gtgctgcagg cggaggatat gcacaggtat tgcctatgga agatatcaac
    23401 ttgcatttta ctggtgacat gcatgctatc acaacagcta ataatgcatt atctgctctt
    23461 ttagataatc atattcatca aggaaatgaa ttgaacatcg atgcccgccg agtgatttgg
    23521 aaacgggtag tcgatctcaa tgatcgtgaa ctgcgtaaag taattgttgg cttgggtggg
    23581 ccaatccaag gtgttccaag agaagatggg tttgatatca cagttgccag cgaaatcatg
    23641 gctatcttgt gtcttgcggc agaccttgaa gatttaaagg ctcgtcttgc aaggatcgtt
    23701 gtcggctata catttgaccg tcagcctgtg actgctggag acttgaaagc agaaggcgct
    23761 ctggcattac tgctgaaaga tgcaatcaag ccgaatcttg tacaaacaat ttacggaaca
    23821 ccagcttttg tccacggggg accgtttgcc aatatcgctc atggctgcaa tagtatttta
    23881 gctaccaaga cagcattgag attagcagat tacgttgtca cagaggcagg atttggtgca
    23941 gatcttggcg gagagaaatt tttagatatc aaagtaccta acttgaaaaa agcgccggat
    24001 gctgtggtga ttgtcgccac tgtccgtgca ttgaaaatgc atggcggaat gaaaaaagat
    24061 gaacttaaaa atgagaatct tgatgctttg aaagtaggtt ttgcaaattt aaagcgccat
    24121 atacgtaata tggaacaata tcagctacct gtgatcgtcg caatcaatga attcgtaaca
    24181 gatacagaca atgaactcac actgttggag cacttgtgtg aaaatcaggg gattcttgcc
    24241 aagagagcga gtgtatgggc agatggagca gaaggcggcg ttgatttagc aaaagctgta
    24301 gtacgattga ttgatagaaa agaagctaat tacaagccat tataccgcct agaagaaacg
    24361 atacaagaaa agacagaaac aatcgtcaag aaaatttacg gaggaaatgg tgttgttttc
    24421 agcaaaaaag cgcaaaaaca aatagaagag tttacgaaga atggatggga caaactgccg
    24481 atttgtatgg caaaaacaca gtattcattt tctgatgatc cttcactgct aggtgcaccg
    24541 gaagatttca ccatcacgat ccgcgaaatc atcccaaaat taggggcagg atttttagta
    24601 gccttgactg gagatgttat gacgatgcct ggtttgccta aaaaacctgc tgcattgaat
    24661 atggacgtga caaatgacgg agaagtgttg ggattgtttt aagcttgatt ataatctacc
    24721 atcgaaggag ctgtattttg actacagctt ctttttttag acgataggga attaattttg
    24781 tttacactag gatcattctt tttctttatt gtattttgag ctatactaaa gcataatagg
    24841 agggtatgat gaaaacgaca tttataagaa aaaccggttt ttacggtatg ggtagctcga
    24901 ttcagctaag aatcaacaat gaaaaacgca gtgttctcag tcatgaacaa aagataacgc
    24961 ttgatctgga agtgcccttt acgatgcagg tcacctttta ttggctaaaa agccccgttt
    25021 atacagtgaa agaagcaaag cctgcttatg tgatcacaat gaattacttg attcttcaaa
    25081 tctatccgtt tttatttcta gcaactgggt tgggggccgt tttcctacaa aatttatttt
    25141 tcagtttttt tgcagttatt gtgttgattg cgttcttttt ctatataaaa aaccgggcat
    25201 atttgatcaa ggaggaaaat tatggcaaac tctgatcttt ttttaatcag tttcaatcga
    25261 atcgaaaaat ggatgagaga cgagatggga aatgcacgaa atatgggatt taccgaactt
    25321 gtcagacgcc tagctcaaag aaaacaatta atgatcagaa aatacgaaga tgatctttta
    25381 cagcttgctc agttaaggaa tgcgatcgtc catgatcgga tcgcagtcga ttttgtcatt
    25441 gcagagccaa atgattggac agtcaagcga atccagctga tcgaacaaga actgattcag
    25501 cctgaaaccg tgctgcctcg atttgcaaaa cgtgtaacag gttttgaaca agatcttccg
    25561 ttacttgaac tgttaaagat agtagcagaa aaaaggtatt cacaatttcc gttatacaat
    25621 aaaggaaaat ttgtagcatt gattacttta cgtaatatcg ggttttggct agcaaaagaa
    25681 agccaaaaag gtccggttga tttaacaaat aaaagagcgt tggatttgat catccaaaac
    25741 ggaaagtaca caaattatca ttttgttcca gctaaaacac atatttacga ggttgaagcg
    25801 atgtttcgtg agcaagggac tttggaagcc gtacttatca ctaaagatgg gaatcccgat
    25861 ggtaatctgc tcgggatcgt acgacctcgt gatatttata aacaaataga aaaggattga
    25921 ttttttgtta attatttatt ggatattcag cgctttgcta gtaggagtgg atcagttggt
    25981 caaatggtgg atcactgata atctagcgct tggagagacg aaaaatctta taccaggtat
    26041 tttgtcactg aatcatattc gaaacactgg agccgcatgg agtatgctag aagggaagat
    26101 gtggttcttt actatagtga cactcattgc agtcgttgtg attctcacat tgatgattaa
    26161 aaatcgtgaa aaaggtaatc gctggttcat gattggattg agtttgattc tagctggtgc
    26221 gattggcaat tttatcgacc gtattcgtct tggctatgta gtagatatgt tccagacaga
    26281 ttttatgagc tttccgattt ttaacgtagc agatgtgaca cttgtatgtg gagtgatttg
    26341 tatgttaatt tatattattt tagatgaaaa ggatcaaaga aaaaaatgac agaacttaaa
    26401 acgacgattc accatgaatc tggtaggatc gataaagtat tgactaattt attcaccgat
    26461 tacagtcgtt cgcaaattca gctgtggctg aaaaatggag cggtttctgt caatggacag
    26521 ccagtcaaag caaattacaa agtaaaacaa ggagacgaga ttactgtctt aatccccgaa
    26581 ccagaaacat tagatgtggt cccagaaaat atcccgttga cgatcgttta cgaagatgaa
    26641 gatgtagcgg tgataaacaa acctcaagga atggtcgttc atccttcagc aggtcatacg
    26701 catggcacaa tggtcaatgc gctgatgtac catatcaagg atctttctac gatcaacggc
    26761 gttattcgtc caggtattgt tcaccgaatc gacaaagata cttccggact gctaatggtt
    26821 gccaaaaatg accaggcaca cgaatcatta gctcagcaat taaaagataa gacctctttg
    26881 cgcaaatatg ttgctttagt ccatggagag attcctcacg aaaaaggaac catcaatgcg
    26941 ccaatcggcc gttcgaagga aaaccggaaa atgcaggcga taagagaaga tgggaagtcg
    27001 gctgtcacac attttactgt attggaacgt ttcgaaggat ttactctggt tgaattaaaa
    27061 ctagaaaccg gaagaacaca ccagatccgt gtgcatatga agtatatcgg ttatccgtta
    27121 gctggagatc cagtatacgg accgaagaaa actttgaaag gcaatggtca gtttctccat
    27181 gcgcaaatgt taggttttac gcacccgact acaaacgaaa agatgatctt tgaagcacct
    27241 cttccagaag tttttgaaaa aactttagaa aaattaagaa aaaacattgc attttaattt
    27301 agataacggt atagtaatta acaacgaaag cataaaactt aatagaattc ctttaagttt
    27361 agtcccgtga ggctaagaag ggtgggagca aggatacgta tggtgcgcca taagtagatt
    27421 gctcattgac atagtatagc tatcagtgta tcagtatacg ctcagtctaa acattcctcc
    27481 tgtcctctta gggcaggagt ttttttatgc aaaaaagtag ggggaatgaa aatgcaagca
    27541 aaagaagtag tagatcaggt aaccatgaag cgagcattga ctcgaattac ttatgagatt
    27601 atcgagagaa accatagtat ccaagatatc gtattggtag gtatcaaaac acgaggaatc
    27661 tacattgcat caagaattgc cgaacgcctg aagcagctag aagatatcga tattcctgta
    27721 ggagaactgg atatcacttt ataccgagat gacaaaaaag aaaatccaga agaaccggaa
    27781 cttcattctt ctgacatccc agtttcctta gaaggaaaag aagttatttt gattgatgat
    27841 gttttgtata caggacgaac gattcgagca gcaatggacg cagtaatgga ttttggcaga
    27901 ccaagaaaaa tttcattagc agtcctggtc gatcgtgggc atcgagaatt gccaatccgt
    27961 gcagattatg ttgggaagaa cattccaaca tctcgggcgg aagagatttt agtagagatg
    28021 caagagcttg atggacaaga tcgcatcatg attttgaaag aggaagatta gaggagagag
    28081 aaacatgtcg gagaaaaaag gatttcataa tgatgacgtg gtgttagata tccacgatcg
    28141 cccaacccca ggacattggg taggattaag tttacaacac ttgttcacga tgttcggagc
    28201 aaccgtgtta gtccccatct tagtaggtat cgatccaggt attgcgctag tcagttcagg
    28261 actaggtaca ttggtgtact tatttactac taaaggaaag atacctgcgt acttaggaag
    28321 cagcttcgct ttcattgcag cgatgcagct tttgatgaaa acagatggtt atccagcgat
    28381 tgcacaagga gcagtcacaa ctggattagt ctatttgatt gttgcgctga tcatcaaaaa
    28441 gatcggttca gcatggctgg ataaaatctt gcctccaatc gtcgtcggtc cagtcatcat
    28501 ggttatcggg ttgggacttg cggcaaatgc agcaacaaat gctatgtata atcagggcac
    28561 gtatgatttc aagtatattg ctgtagcgct gatcacatta ggattaacaa ttttcttcaa
    28621 catgtggcta agaggttttc tcggattgat tccgatttta ctaggtatta ttagcggata
    28681 catcgtagcc ttgctgtttg gaatcgtgga tactaagcca atcgtagacg ctgcctggtt
    28741 tgctgttcct aactttgaga ttccctttgt acaatatgaa ccaaagctat atcttggagc
    28801 aatcacaaca atggcaccca tcgcttttgt gacgatgaca gagcatatcg gccatcttat
    28861 ggtattgaat aaactaacta aacgtaattt ctttgaagaa ccgggtcttc ataagacgtt
    28921 gacaggtgat ggattagcac aaatcgtggc agcctttgtc ggaggtcctc ctgtaacaag
    28981 ttacggtgaa aacattggtg ttctggctat cacacgtgtc catagcgtgt ttgtgatcgg
    29041 tggagctgca gtatttgcag tcattttagg attcgtagga aaattaagcg ctttgatttt
    29101 aagtatccct ggaccagtca tctcaggaat cagttttatc ttatttggag taattgccgc
    29161 aagtggaatg aagattttaa tcgagaacaa aatcgatttt gataaaaaga aaaatctgtt
    29221 gattgcttca gttatcttag tagtaggaat tggcggactc gtctttgaag taggcacatt
    29281 tacattgtcg gcaatggcat tagcaactgt acttggcatc attttaaatc ttatcttacc
    29341 agaaacttca cgaagcgaag aaaactaagg aggaaacatt atgatcatca aatcagaacg
    29401 tatcagctta aagcatttat tgaccgttga ggcacttact gatcaagaag ttatgggctt
    29461 gatccgcaga gggcaggaat tcaagcaagg tgctaattgg actccgcaaa agcgccagta
    29521 ctttgctaca aacctctttt tcgaaaatag tactcgcaca cataaaagct tcgatgtagc
    29581 ggagaaaaaa ctagggctag aagtgattga atttgaagca agcacaagct ctgtccaaaa
    29641 aggggaaaca ctatacgata cagtactgac gatgtcagca ttaggcgtag acgtagcggt
    29701 tatccgtcat ggtgatgaga actattatga cgaactgata caaagtaaaa caatccagtg
    29761 ttcgattatc aatggaggag acggaagcgg acagcatcca acccaatgct tgcttgattt
    29821 gatgaccatt tatgaagaat ttggtcattt tgaaggtctg aaagttgcca tcgtaggtga
    29881 tatcactcac tctcgcgtag ctaaatccaa tatgcagatg ttaaaacgtc taggcgcaca
    29941 agtattcttc tcaggtccta gagaatggta cgacgatgaa ttcgaagtgt acggacatta
    30001 tatgccattg gatgaactac tagatcaagt tgatgtcatg atgatgcttc gggtgcaaca
    30061 cgaacgccat gatggaaaag aaagtttctc aaaagaaggc taccatcagg aacatgggtt
    30121 aacagttgag cgtgcgaaga agttgcaaaa acatgcaatc attatgcacc cagcaccagt
    30181 taaccgtgat gtagaattag ctgattcatt agtggaagga ttacagtcgc ggatcgttca
    30241 gcaaatgagc aatggagtat tcgtcagaat ggcaatctta gaagcagtgc taaatggaaa
    30301 agcgtaatta taggaggatg aaaaaatgaa aacactcatt aaaaacggtc agatcaatac
    30361 acgaaaaaat atgacgacac cagcagaaat ttggatagaa gatgggcgaa tcaaagcaat
    30421 cggtacagga ttctcagaag ccgaatttga tgaagtgttt gatgcaaagg gacaattgat
    30481 cacacctggt ttagtggacg tccatgttca tttgagagag ccaggattta catacaagga
    30541 gacgatcgaa gctgggactc gctcagctgc tcgtggcggt ttcactactg tatgcgcgat
    30601 gccgaattta aatcctgtac ctgatacggc agaaaagctg agacaagtat atgacatcat
    30661 tagaaaagat gcagttgtga aggtattgca gtatgcgcca atcacagaaa atctgcgaag
    30721 tgagaaatta gttgatcaag aagcactgat tgaagaaggt gcttttgctt tcacaaatga
    30781 cggtgtaggt gtccaaacag ctgggacgat gtatctggct atgaaagaag ctgcaaaaaa
    30841 caataaagcc ctagtagccc atacagaaga tgaatcttta ttatttggcg gcgttatgca
    30901 cgctggcaag aaggcagaag aacttggtct tcccgggatc ttaagcgtaa ccgagtcttc
    30961 tcaaattgct agagatctgt tgctagctga agcaactggt gttcattacc atgtttgcca
    31021 tgtttctact aaagaaagtg tccgtgtaat cagagacgca aaaaaagcag gaatccacgt
    31081 aacagcagaa gtttcacccc atcatcttat tttgatcgac gaagatattc ccgaagattt
    31141 cggcttttgg aaaatgaacc cgccgctaag aggacgggag gacagagaag ctttgatcga
    31201 aggcttgctt gacggtacga tcgattgcat cgctacagac catgcccccc atggattaga
    31261 agaaaaaagc caaagtttca tgaaatcacc atttggtatc gtaggaagcg aaacagcgtt
    31321 tcaactgatc tatactcatt ttgtagaaac tggtcgattc acgttggaac aagtgatcaa
    31381 ttggttggca gttaaaccgg ctgagatttt tggtttgaat gcaggaacgc taacggttgg
    31441 tgcccccgct gatgtagcag tttttgatat tacacaaact tgcacgatcg ataaagaaga
    31501 ctttttatca aaaggggaga atacaccttt tatcggctgg aaagtaaaag gcgaaacaca
    31561 aatgactttt gtcaacggaa aacttgtgtg gcagaaggga gaataaaagt atggaacgtt
    31621 tgcttatatt agaagatgga acagttttcg aaggaaaggc ttttggtgca gatgctagtg
    31681 tcttcggaga aatcgttttt acaacaagta tgactggtta tcaagaaact atcactgatc
    31741 aaagttttaa cggtcaaatc attacattta cctatcctat ggtgggtaat tatggggtaa
    31801 atagagatga ttatgaatcg atttctccaa catgcaaagg agtagtagta aaagaacatg
    31861 cacgtgtagc ttcaaactgg cgaaaccaaa tgacgctaga ttcatttttg aaacaaaaag
    31921 gaattcctgg aatatcaggt atcgatacgc gcgcccttac tcgcaaaatc cgtgaagtcg
    31981 gaacgatgaa agctagtata gttgatgctg gagattcctt cgaacatgca tttgatcagc
    32041 tgaaagcaac cgttctagca accaatcaag tgcagcaagt ctcaactaac aaaccttatc
    32101 caagtccagg aacaggtcgg aaagtcattg tcattgactt cggcttgaaa catagtattt
    32161 tacgagaatt gagtaaaaga aactgtaacc tcacagtact tccctataac acagatgccg
    32221 agacgatttt agcgctatca ccagacggag tcatgctgac gaatggacct ggtgatccaa
    32281 aagatgtgcc agaagcaatc gaaatgatca aaaaaatcca aggaaaagta ccgatttttg
    32341 gtatttgtct cggtcaccag ttatttgctt tagccaacgg tgcagatacc tataaaatga
    32401 aattcggaca tcgaggatta aatcacccgg tacgagaagt agcgaccgga agaattgatt
    32461 ttacttctca aaatcatggc tatgcagtcg atgaagccac gattgatcca gaaaaactca
    32521 tcgtaactca tgtagaagta aatgacggaa cagtagaagg agtcaaacac agagattatc
    32581 ccgctttcag tgtgcagttt catccagatg ctgcccctgg tccgcatgat gcactacatt
    32641 tatttgatga atttatggaa atgatggacg caggaaagga gcagtaaaca gatgccgaaa
    32701 cgtacagata tcaagaaaat tatggtgatt ggatctggtc cgatcatcat tggtcaagcc
    32761 gcagaatttg actacgcagg aacacaagcc tgccttgcct taaaagaaga aggatatgaa
    32821 gtggttttag taaattctaa tcctgcgacg atcatgacgg ataaagaagt ggcagatcaa
    32881 gtatatatcg aaccgatcac acttgaattt gtatcaagga ttcttcgaaa agagcgtcca
    32941 gatgctctcc ttccaacttt aggcggacag acaggcctca atatggcaat ggagctggca
    33001 gcatcaggta ttttagaaga attgaacata gaacttctag gaacaaagct ttctgcgatc
    33061 gatcaagcag aagatcgtga tctattcaaa cagttgatga aagaattgaa tcagccaatc
    33121 cccgagtctg aaatcgtcaa tacagtagaa gaagctgtag attttgcaaa taaaatcggc
    33181 tatcctgtca tcgttcgtcc agcctttact ttaggcggaa ctggtggagg tatgtgtgaa
    33241 aatgaagaag aattacgtat cgtatcagaa aatggattaa gtctttcccc cgctacccaa
    33301 tgtttgattg aacgaagtat tgcaggtttt aaagaaattg aatatgaagt gatgagagat
    33361 tcggctgata atgcaatcgt tgtctgcaat atggaaaatt ttgacccggt gggtatccat
    33421 acaggtgatt ctatcgtatt tgcccctagt caaacattgt ctgaccatga atatcaaatg
    33481 cttcgtgatg cttctctttc gattattcga gcacttaaga tcgagggagg ctgtaatgtc
    33541 caactcgctc ttgatccaca tagttttaat tattatgtga ttgaagtcaa tccgcgtgtt
    33601 tctcgttcat ctgcgttagc aagtaaggcg actggctatc cgatcgctaa gctagctgct
    33661 aaaatagcgc ttggattaac attagacgaa atgaaaaatc ctgttacagg aacgactttt
    33721 gcagaatttg aacctgcatt agattatgtt gtagctaaaa ttcctcgctg gccgtttgat
    33781 aagtttgaaa acggagaacg gcttttaggc acgcagatga aagcaactgg tgaagtgatg
    33841 gctatcggtc ggaatatcga agagtcttta ttgaaagctg tgcgttcttt agaaatcggt
    33901 acacaccata tcgaacttcc tgagttggca gacatcacgg acgatgacct aatccaaaaa
    33961 gtggttcgag cacaagatga tcgcctgttt tatgtagctg aagctattag aagagggtac
    34021 accatagaag aattagcgga tttgacaaaa atcgatttat tctttttaga taaactgttg
    34081 catatcgtag aaatcgaaca gcagttgaaa cagcagccgt tggatgacaa gatattgaaa
    34141 acagcgaaac aaaacggttt tacagacaaa aaagtggcgg agctgtggga aataaacgaa
    34201 gaagccgttc gccagatgag aaaagaaaat gatttgattc ctgtatataa gatggttgac
    34261 acttgtgcag cggaattcga atcaaaaaca ccttattttt atagttccta tgaatatgaa
    34321 aatgaaagtt cacgatcaga aaagccctca attctagtac tgggatctgg tcctatccgt
    34381 atcggacaag gggttgaatt tgactatgcg actgtgcatt ctgtcaaagc aatccagcag
    34441 gcaggatacg aagcaatcat catgaacagc aatcctgaaa cagtttcgac tgacttttct
    34501 atttcggata aattatattt tgagccattg accttcgaag atgtgatgaa tgtgatcgag
    34561 ctagaacagc cgataggagt aatcgttcaa tttggtggtc agacagcaat caacttagcc
    34621 gaacctttga ctgctgctgg tgtaaaaatc ttagggacaa cgatcgaaga cttggatcgt
    34681 gcggaaaatc gtgatttatt cgagcaagcg ctgaaagagt tggatattcc tcaaccttta
    34741 ggggatactg ctacaagtaa agaagaagcc gtggttatcg cttcgagaat tggttatcca
    34801 gttcttgttc gtccaagcta tgtattaggc ggacgtgcga tggaaatcgt tgaaaaccag
    34861 cgagatttag aagattacat ggaacatgct gtgaaagcat ctccagaaca tccagtacta
    34921 gtggaccgtt acttgcttgg tggtgaatgc gaagtggatg cgatttgtga cggtgaaaca
    34981 gtactcatcc cagggatcat ggagcatatt gagcgtgctg gtgtccattc aggggattca
    35041 atggctgtgt atccacctca aacattatct gaatcgatca agaaaacgat cgaagattac
    35101 acgatccgct tagcattagg tttgaattgt gtcgggatga tgaatatcca gtttgtcatc
    35161 catgaaaatg aggtttatgt gatcgaagtc aatcctcgag caagtcggac tgttccattc
    35221 ttaagtaagg tgacaggaat tccaatggca caaattgcga cgaaagctat tttgggagag
    35281 aaactaaaga cacttggtta tgaaaacgga ctttatccag aaacaaaaga agttcatgtt
    35341 aaagcacctg tcttttcttt tacgaaattg cagaaagttg atacttactt agggcctgaa
    35401 atgaaatcga ctggagaagt aatgggatct gacagacaat tagacaaagc tttgtacaag
    35461 gcattcgaag cttctggatt acacttgcct gaatatggag ccgtattatt tacgattgcg
    35521 gacgaaacaa aagaagaagc actagaatta gctaaacgtt ttacagaaat tggctatagt
    35581 ctgataggaa cgaaacatac agctgcttat ttcgaaaaaa atggtctggt cgttgaaaca
    35641 gtagcgaaaa tttctgagga agcagcagaa aaaaatgtag tcgacttaat aagagatggt
    35701 aaaacacaag tggttgtcaa tacgattgat aaagatcggg gaaatgcttc taaagacggt
    35761 ttcatcatcc gaagagaagc agttgaacat ggtattccat tgtttacttc tttagacaca
    35821 gcagatgcga tcgttcgagt gatggaatcc cgtgcttttt caactaaccc tatttaacgg
    35881 cgagcacatg ttaagacaaa aagacgaaaa accgttgcag gaggggacag atgaaacaag
    35941 aaatgatgga aatcgttcag caaaaacagc tggcaccaaa gatttttgaa atgacattga
    36001 aaggtgatct agtaaaagaa atgcagcaac caggacagtt cttgcatatt ctcgtgccgc
    36061 gtgcagactt gctattacgc cgaccgatta gcttgaatca tatcgaccac gaaacaaata
    36121 cttgccgtat catttatcgg gtggaaggtg aggggactag agtcttctct actctttctg
    36181 ccggagacca tttagatgtc atgggtcctt taggcaatgg ttttgatttg tccaatcttc
    36241 atacaggaga cgaagtattt ataatcggtg gaggaatcgg tgtccctcct ctatatgagt
    36301 tatcaaaaca gttagtcgaa aaaggaatta agccaacgca ttttttaggt tttgccacac
    36361 atgaagtcgt ttattatgaa aaagaattta atcgtctagg agaaacaaga atcgctactg
    36421 acgatggaac atacggtatg cacggaaatg tcggtaattt attgttagga acgaagacgg
    36481 aacctacagc tgtttttgca tgtggttcaa acgggttatt gaagacagtg gaacagctgt
    36541 tttcttcgca tcaaaatgtc cagttatcat tagaatcccg catggcatgt gggatagggg
    36601 cttgctatgc ttgcgtttgt catacgccgg aagatgaaac aggaacaaaa agtgtgaaag
    36661 tttgtgacga aggaccgatt tttaaaatag gagaggtaat tatatgaatg agaatccttt
    36721 agcggtcaaa cttcctggcc tagaattaaa aaatcctatc atgccggcaa gcggctgttt
    36781 cggttttggc aaagaatacg gaaaatacta tgatttgaat cagcttggat cgatcatggt
    36841 caaggcaacg actccaaatg cccgctttgg caatcccacg ccaagagtgg cggaaacacc
    36901 atctggcatg ttgaatgcaa ttggtttgca aaatcctggt ctagacgttg ttatgcataa
    36961 acttcttcca gaattagagg agtacaatga gttacccatc atcgcaaatg ttgctggtgc
    37021 ttgtgaagaa gactatgtag aagtttgtag caaaattggc gaagcaccaa atgtgaaagc
    37081 aatcgagctg aacatttctt gcccaaatgt caaacatggc ggaattgctt ttggaacaga
    37141 ttctgatgtt gcttttcaat taacacaagc agtaaagaaa gtttcttctg ttcctgtcta
    37201 tgtcaaattg tccccaaatg taacagacat cgttccaatc gctcaggcaa tcgaagctgg
    37261 aggggcagat gggtttacga tgatcaatac tcttcttggt atgcggattg accttaagac
    37321 aagaaaaccg attttagcca atcaaacagg tggactctcc ggaccagcaa tcaagcctgt
    37381 cgctattcgt ttgattcacc aagtagcaag tatatccagc cttccaatca ttgggatggg
    37441 cggcgtgcag acagtggatg atgttcttga gatgtttatg gctggagcaa gtgctgtagc
    37501 tatagggacc gcgaatttca ccgatccgta tatctgtcct aaactaatta aagagctccc
    37561 tgtgcgaatg agcgaactag gcatcgaatc gctggaaaga ttaatcaaag aagtgagaga
    37621 ggaacgtgaa cgatgaatca actagaccaa cgaccaatta ttgcattaga tttttcaact
    37681 aggcaagagg tagaagactt tcttcgattt ttcccgaaag aagaaaaatt gtttgtgaaa
    37741 atcggaatgg aattgttcta ccaagaagga cctgaaatcg tacgttatct aaaagaggct
    37801 ggtcataatg tatttttaga tctgaaactt cacgatattc cgaatacggt cgaaaaagca
    37861 atgcggggat tggcaaagct tggtgttgat ctcacctgtg ttcatgccgc tggcggtatt
    37921 cgtatgatgg aggcggcaat gcgaggatta gaagagggga ctccagaagg tggaaaacgt
    37981 ccgctacttc tagctatcac tcagcttact tctacaagtg aagaagaaat gcatgccgat
    38041 caactaatcg aagtttcttt agaaaaaagt gtgatccatt atgctagctg tgccaaaaaa
    38101 gcaggattag atggtgtggt ttcttctgct tgggaagtag aagcgatcaa agaaatggca
    38161 ggagacgaat ttgtttgctt aactccgggt ataagaccag aaggaacagt cgcaggagat
    38221 cagacaagag tagtcacacc ttctcaggca aaaaagatcg gctcaacttt tatcgttata
    38281 ggtcgaccaa tcactcagtc aactaatcct tataaagcat atcaaacgat tcaaacagaa
    38341 tggagctaac ctaaaatgaa tgttgaacaa agtatcgcaa aagacttatt agaaattgaa
    38401 gcagtatttt taaatccaag taatcctttt acatgggcaa gtggaatcaa aagcccaatt
    38461 tactgtgata accgaatcac gatgagctat ccaaaagtcc gaaaagagat cgcaaaagga
    38521 ttagcaagca aaatcaaaga agcttaccct gaagtacaag tgattgctgg aactgcaaca
    38581 gcaggaatcc ctcatgccgc atgggtagcg gaaatactgg atttgccaat ggtctatatt
    38641 cgaagtaagg cgaaagatca tgggaaaggt aaccaaatcg aaggacgtat atttgaaggt
    38701 cagaagatgg ttgtgatcga ggatttgatt tctacaggcg gaagtgtctt ggaagcagct
    38761 gaagcagcaa aaagagaagg tgcggatatc cttggtgttg cggctatctt tacgtatgag
    38821 ttgccaaaag gaaaagcaaa tttcgaaaaa gccgaaatcc ctcttatgac gttgaccaat
    38881 tattctgtat tgattgaagc agctttagaa gatcgttata tcgatgagca agaattaact
    38941 ctgctaaaag aatggaaaaa agatcctgaa aattggcaga tttaagcgcg cttgatgaag
    39001 atagagaaat ccgatttgtg tctccagaat catcaattgg aatagcaaaa atccaaaaac
    39061 tgattgcgag aagcatcttt tcatcaggta tgaaaagaaa cttctatcgt gatcagtttt
    39121 tgattttttt aaaattcatt tttctaagac tggttagcag aaagaagaga ataatctctt
    39181 ctcttttttc tattatatat agattttctc tattttttgg taagggagct gtttcaaaaa
    39241 tggtaaagag cggaaatgtt gcgaatatca gttatttaat gatatgatat tcggaaaaag
    39301 aaatctcaaa gggaggtaac ttttatgggg ttgaatgaat ttattttagg attgaacaat
    39361 ttagagacga tcacaagggc acctggattt tttaaatata cagagcatac agttgcagca
    39421 cattcgtatc gtgtagcatc tattgcgcaa gttctaggag acattgaaga agcgaatgga
    39481 caaccgatcg attggaaact gctctatgaa aaatcattga atcatgacta cacagagcgt
    39541 tttattggtg atatcaaaac gccggtgaaa tacgcaagca aagagttaag agggatgctg
    39601 caaacagttg aagaaaagat gacggacgaa ttcatcaacc aagagattcc agctgagttc
    39661 caagaagttt atcgccgtcg gttgttcgaa ggaaaagatg aaaccgtaga aggagaacta
    39721 ttagccattt cagataaggt tgaccttctt tatgaatctt ttgatgaaat catcaaaaat
    39781 aacccggaaa aagtttataa ggagatgttc attgaggcag tgactacgat taaaagcttt
    39841 gaacatcggc cttctgttca gtatttcttt aaagagatat ttccggaact attgaaccag
    39901 gaattttatg gaaaagaggc gtttttagaa accgtctcaa cgattgtaaa gaaagaagaa
    39961 aaataaaaat gatatgagat gcagggggaa gtatagttga aaaagaatat ggatgtcgaa
    40021 tggggctatt ctggagacaa aggtccggaa aattgggcga gtttatgtga ttggtttgcg
    40081 agaggtgcgg aatttccatt gcagtcgcct attcatttga ccaaggggga agaaaccaaa
    40141 atagaaggag acacgctttc ctttcattat caaaagcaac ggtttactga caaggaattc
    40201 aaaaacacga ttcatttagt accttttgac caactcagtt atgtagagtt caagaaagaa
    40261 cgctattatt tgacagatat tcatttccac ttgccttctg aacatatcat caacggaaaa
    40321 caggaagata ttgaatttca ttttgttcat atgaacagca aaaaagagaa tctagttgtg
    40381 ggtgtcatgt accagctaat ggtacaggaa ggttggctgt ataatcaaga aaatggggaa
    40441 agttggaact tagaaaaaca tgagcattgg gtaaatccgg atgtgttctt tccggagcaa
    40501 aaaagccatt tccattatat tggctcattg acaactccgc ctaccagcgg gccaatccaa
    40561 tggtttgtaa tggatcatgt aggaaaactg aaccaagagt ttcttctccc cttcgatggt
    40621 cagtatgctc gaccgaacaa ccgaccaatc cagcccttga atggaagaga aatttattat
    40681 ttcgaggagt ttgagcaatg aatattcagc agatgaaata cgtggtcgct gtagcaaaca
    40741 atggtagttt cagagaagcg gcaaagaaaa tgtttgtctc ccagccaagt ctttcagctg
    40801 gtatcaaaga attagaaacc gagttaggga tcacgctgtt tactcgaacg aatcgagggg
    40861 catatttaac agaagaaggg caagacttct taaatcgtgc cgagaaaata ttggtccagc
    40921 ttgatacatt agaaactcac tatctaacga gtgaaaagag agacaatttt tcgatcgctg
    40981 cccagcatta tgatttctta ggtcctttga ccgcacagct actcgaggaa ttcaaagacg
    41041 agatcaaaca atttcggatc atggagacga caacagcgag agtgatcgaa gaagtcaaag
    41101 agcagcacag tgagatcggc attatttata tgaatgagca taatcaagct ggtatcagaa
    41161 gatatttaca acaaggagag ctaagtggcc gcagcattgg aaaattcaaa acgcatattt
    41221 ttttaaggca aggacatcca ttagctgaac acgcagagat caccaaagaa gaattgttat
    41281 cttatcctca agttcgtttt acacaggatg gaaataattt cccgtatttt tatgaagacc
    41341 ttatcgagat ccctgatcaa gaaacagtga tttatacgag tgatcgaggt actttgatga
    41401 atatcgttct tgaaactgat gcttacgctt caggatctgg tattgtgatt ggagggattc
    41461 gcgagcactt gcggttaatc cctttggcag aaggcgaact aaatgaattt tatatcattt
    41521 attcggcgaa acgtccgctc agtgaaatcg ctcaaagatt tatcaaagag cttactcggt
    41581 tactggacca gcagagctaa gaaaagcaga tgagaacgct gtttattgaa caccgttgat
    41641 caaaaaagag gggttgtgac agaattttgt cacaactcct ctttttgtag caaacaattt
    41701 ataactaatt gctgttgtgg gaaagtacgc aaatatgatt ctagaaacac tcattgatta
    41761 cctgttttgt ttcatagctg taattttttc ttcttctggt gtcacgataa tcgtcttttg
    41821 gttttcataa ataacataac caggcttggc gccatttggt tttcggatat gctttacctg
    41881 tacaagatca accggcactt gggcagagta tcggtatttt gaaaaatagg cagctaactc
    41941 ggcagcttct gtaattgttt catctgaggg cttgtcactt ttaatgatga cgtgcgaacc
    42001 gggtatattt tttgcatgaa gccaatagtc ggttttttta gctgtcttca ttgtcagctg
    42061 gtcattttga agattgtttt taccaacaag aatgagcgtt ccgtcagaag aaaagtattg
    42121 atcaggctga gatggtttct tacgtttttg tttttttaag ttcttctttt tcaggtatcc
    42181 ttctgaagtc aattcttctt taattgcttc gatatccatt gggccggcaa tttccagttg
    42241 agataagaca gattcaagat attggatttc atctttggct tcttggattt gttcgccaat
    42301 cagcttaaca gcgttcttca gcttttggta tcgatggaaa tatttctgtg cattttgatt
    42361 tggtgtcaat gccggatcta gtgctatttt gattggccga tcttcttcat aataattagg
    42421 taaaacaact tcttttgcgc cgcgtggtac ttgtgtcaga aaagtagtaa gtagttcgcc
    42481 atttctacgg taattctcag cgttttcgga ttctttgagt gtttgttcac gttttttcaa
    42541 tttattttta tttcgtttta gttcattttc gatttttcga atcagttctc cgccttgttg
    42601 ttttgcccga tctttctctg ctttttcgtg ataatagcta tctaataatt gactgagtgt
    42661 tggataagct gttacagcag atgcctgttc ggacaatacc tgataagcaa tcggtgtgaa
    42721 aaaatcttta ttttccgttt cgtaaaaagt aggaataggc tgatggctga tggctgagaa
    42781 aaattcgtcc catacaacca tcttttcatt aggacgttcc agtaatcttt tggtcagctc
    42841 ttgagcgata tcgaaaccga ttccctgaaa ctgacgttgg attgcttttg gatctagttc
    42901 agtttgggaa agccgctgaa agattttttc tttctcggag ctaaatgggt tcaagacctc
    42961 ttgttttggc ggagcaacat attctacacc aggaagcaaa gaacgataag tgttttgaga
    43021 gcttccaatg tgtttgatcg catccagtat ttttccagtt tctcgattaa ctaagacgat
    43081 cgtactatga cgtcccatta attcaacgat caatatgata ttttgtagat cacccaactc
    43141 gtttcgttta gcaaagtgga aatggatcac tcgatcattt tcgatttgtt cgatgtcttc
    43201 taaaatagcg ccatccaaat attttcgaag catcatcacg aagttaggcg gattatcagg
    43261 attctgataa tcgatttggg taatctgtac acgagcataa cttgggtgcg cagataataa
    43321 taatcgatgg tttttgccgc gtgaacgaat caccagcacg atttcatttt cataaggctg
    43381 atggattttc gagatccggc cagatagtaa cgtttcacgc aattcgttga ccatcgcgtg
    43441 ggtaaataca ccatcaaagg acatggttca ttcctcattt cttttcataa gtatattcat
    43501 tataacgaaa aaaagaagaa aaaccaattt ggccgaatag taaagcaaaa gtctagaaaa
    43561 atcttggact aattacataa aaaacagtgt ttctatcgtt gaaatccaaa tttttaggt
//
LOCUS       DAMEEU010000017        41518 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.017, whole genome shotgun sequence.
ACCESSION   DAMEEU010000017 DAMEEU010000000
VERSION     DAMEEU010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 41518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.017"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..756)
                     /locus_tag="PB779_000936"
     CDS             complement(<1..756)
                     /locus_tag="PB779_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0738476.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEESTLRSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFSNRLTPYALTLIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
     gene            complement(1014..2291)
                     /locus_tag="PB779_000937"
     CDS             complement(1014..2291)
                     /locus_tag="PB779_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738477.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCRYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(2370..3014)
                     /gene="pcp"
                     /locus_tag="PB779_000938"
     CDS             complement(2370..3014)
                     /gene="pcp"
                     /locus_tag="PB779_000938"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HDE0738478.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(3213..4157)
                     /locus_tag="PB779_000939"
     CDS             complement(3213..4157)
                     /locus_tag="PB779_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HDE0738479.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(4159..4845)
                     /locus_tag="PB779_000940"
     CDS             complement(4159..4845)
                     /locus_tag="PB779_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HDE0738480.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            5319..5639
                     /locus_tag="PB779_000941"
     CDS             5319..5639
                     /locus_tag="PB779_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HDE0738481.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            5793..6698
                     /locus_tag="PB779_000942"
     CDS             5793..6698
                     /locus_tag="PB779_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738482.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            6695..7468
                     /locus_tag="PB779_000943"
     CDS             6695..7468
                     /locus_tag="PB779_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDE0738483.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(7649..9073)
                     /locus_tag="PB779_000944"
     CDS             complement(7649..9073)
                     /locus_tag="PB779_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0738484.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            9284..9730
                     /gene="nrdI"
                     /locus_tag="PB779_000945"
     CDS             9284..9730
                     /gene="nrdI"
                     /locus_tag="PB779_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDE0738485.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(9795..11777)
                     /locus_tag="PB779_000946"
     CDS             complement(9795..11777)
                     /locus_tag="PB779_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0738486.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(11791..12687)
                     /gene="murQ"
                     /locus_tag="PB779_000947"
     CDS             complement(11791..12687)
                     /gene="murQ"
                     /locus_tag="PB779_000947"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDE0738487.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(12690..13751)
                     /locus_tag="PB779_000948"
     CDS             complement(12690..13751)
                     /locus_tag="PB779_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDE0738488.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(13962..14528)
                     /locus_tag="PB779_000949"
     CDS             complement(13962..14528)
                     /locus_tag="PB779_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDE0738489.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(14556..16058)
                     /gene="eat(A)"
                     /locus_tag="PB779_000950"
     CDS             complement(14556..16058)
                     /gene="eat(A)"
                     /locus_tag="PB779_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDE0738490.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(16316..17437)
                     /locus_tag="PB779_000951"
     CDS             complement(16316..17437)
                     /locus_tag="PB779_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDE0738491.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            17563..18504
                     /locus_tag="PB779_000952"
     CDS             17563..18504
                     /locus_tag="PB779_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDE0738492.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(18654..19550)
                     /locus_tag="PB779_000953"
     CDS             complement(18654..19550)
                     /locus_tag="PB779_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDE0738493.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            19819..21159
                     /locus_tag="PB779_000954"
     CDS             19819..21159
                     /locus_tag="PB779_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0738494.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            21377..21820
                     /locus_tag="PB779_000955"
     CDS             21377..21820
                     /locus_tag="PB779_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HDE0738495.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(22324..23742)
                     /gene="nhaC"
                     /locus_tag="PB779_000956"
     CDS             complement(22324..23742)
                     /gene="nhaC"
                     /locus_tag="PB779_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDE0738496.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(24145..25368)
                     /locus_tag="PB779_000957"
     CDS             complement(24145..25368)
                     /locus_tag="PB779_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HDE0738497.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(25399..26238)
                     /locus_tag="PB779_000958"
     CDS             complement(25399..26238)
                     /locus_tag="PB779_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HDE0738498.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(26255..26935)
                     /locus_tag="PB779_000959"
     CDS             complement(26255..26935)
                     /locus_tag="PB779_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738499.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(26937..28010)
                     /locus_tag="PB779_000960"
     CDS             complement(26937..28010)
                     /locus_tag="PB779_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738500.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(28066..28304)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(28347..28580)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(28657..29328)
                     /locus_tag="PB779_000961"
     CDS             complement(28657..29328)
                     /locus_tag="PB779_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDE0738501.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(29415..32093)
                     /gene="mgtA"
                     /locus_tag="PB779_000962"
     CDS             complement(29415..32093)
                     /gene="mgtA"
                     /locus_tag="PB779_000962"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HDE0738502.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            32752..33189
                     /gene="ndk"
                     /locus_tag="PB779_000963"
     CDS             32752..33189
                     /gene="ndk"
                     /locus_tag="PB779_000963"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HDE0738503.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(33211..34077)
                     /locus_tag="PB779_000964"
     CDS             complement(33211..34077)
                     /locus_tag="PB779_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDE0738504.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(34237..36330)
                     /locus_tag="PB779_000965"
     CDS             complement(34237..36330)
                     /locus_tag="PB779_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDE0738505.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
     gene            complement(37079..37702)
                     /locus_tag="PB779_000966"
     CDS             complement(37079..37702)
                     /locus_tag="PB779_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738506.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
     gene            complement(37861..39258)
                     /locus_tag="PB779_000967"
     CDS             complement(37861..39258)
                     /locus_tag="PB779_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0738507.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            complement(39290..40261)
                     /locus_tag="PB779_000968"
     CDS             complement(39290..40261)
                     /locus_tag="PB779_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0738508.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            40635..41060
                     /locus_tag="PB779_000969"
     CDS             40635..41060
                     /locus_tag="PB779_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738509.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
BASE COUNT        11984 a         8667 c         7293 g        13574 t
ORIGIN      
        1 tttttgttcg agtaaatctt ggagaagttc ggcgtaatag atcgtttttt gacagtggat
       61 actgtctttt tcaacagctg gataggcaca ctgtgcatag tggatgattt gatctgcctt
      121 ttgctcggca cgattcgcgg agattttttt ccgtgtttcg ttgatcagtt tattttttat
      181 ttttgtccga gtagatgcca atacaaaatc tggatgggga aaaagacgga tcaatgtcaa
      241 tgcgtaaggg gtcagcctgt ttgaaaagaa ctgttcaagc tctggaaaag tcaattgaag
      301 gcagttgtgt aaatccatgc gcagacgagt gattttcttc tcaatttctt gataaaaacg
      361 ggctaaatcg cgcatctcta agtaaaaatt gctttgtact tcttttggct gacgttgatt
      421 tttaagatga gtctgtgcga gccggtgggc atccgattta tctgttttcc aactgcgtaa
      481 ggtgctttct tccatctgtt ttttcgcctc taacgggttt aacaaacagt aagaaaagtg
      541 atgatcttga aagaactttt cgactggtct ggaataaatc cccgttgctt caaaaacaat
      601 caatggacgc tcaggcaagt gctggatctc ttcgagtaat gcatgaaatc ctctttgagt
      661 gtgttcaatc tcgtcttcaa ataagcaggt gtcgtctttg tataggacac tgtagctgtg
      721 tcccattgaa acatctaatg caagaatgta aggcatttgt tttcctcctt tttaagtttt
      781 gaaagaactt tactgcttca tttcgattcc aatttcctat acacgggctc atggccccaa
      841 catacgtaaa cctgattcta aaatgacagt aaagaagttc ggtttttgat agggactcgt
      901 agtcctcaag gctttgttcg aactttcttt cactcttcac tataatctaa aaatagaaaa
      961 tagaggagaa catcattcgt caatgatgtt cccctctaat cttagtatgt tttttatagt
     1021 aattccttca gatactttct tgcctcatca ttgaaacgca gtgattcttc taacttctga
     1081 taatattcca acgcttgttt ctgagcttca gtaaaacgat aatgttttcc tttccatttg
     1141 tcgattgtct cttgcacatt tccagattgg atatctttca ctactagttg ccatttttct
     1201 tttgagactg tacggtcttt cttatcagca gattgtatag cttctcgttc tttacgcaat
     1261 acttttaaaa aaccatttct gactatccga ggaatgctgt cgaagaaccc ttctgtaaaa
     1321 ccatagcgac aatattgctt ccaaataaat agatagattt ttggttggat gaatcgttgg
     1381 tttttcgcaa aatattccat ctgagcagtg acttctggtg ttcgttgacg ttttgtcttt
     1441 ctcaacacgg aaataaatgt ttcaaaataa gcattaggat gtactggcac ttcttcatat
     1501 acgatggatt gccaatcttt acgtaaaaat gcgcgatagt tgatcaagaa ttcttctaca
     1561 tcctttacta attcttctgc aaagtcgtca aatagttctt tttttatctg tcgctttttt
     1621 gactgcccat tgatgtgttc acttattttc ttgatttcat tttccaatgc ttgataatcc
     1681 gctatgtaaa tcggcatttc tacttggcga aattctgcga gccgctgagc taattttata
     1741 tccggtaaat atggctgttt catccgacga ttttggtaca agacaaaaca gtatttttgc
     1801 catagtcctt caggaaaatc gatattcttc tgcttaagcc ataataattc gtctaaggcc
     1861 agatcaactt ttgtcattcc ctgatggatc gaagctgcca ctgtcggaga gacatgcagg
     1921 tgatcggcaa agtggttgat gcctagtttt aggatctttc cggtttttgg cgatttaacg
     1981 atgtattgca cttttaattc tctaccacac tcacaataca atttttgctg gcttcgtttt
     2041 gttcgaaaaa acggattgat cttgaagtca gaaaacaccc aatctgttgc agctaaataa
     2101 tgttcttcca taaaacgaga gctgattaga tatcggcggt gcttatcgac tagttcccgc
     2161 tgttttttcg ttaattttgc atagatctcc caacgttgac tgcttgtgta ttgtttagaa
     2221 attttgatgg gatagctttt gctgatttct tttggaaacc attcttcaaa gacggattgc
     2281 cattcttcca cggctgtttc tttcctttct aattacaaaa agctggctac taacataacg
     2341 ttagcaacca gccagtgttt cttgctaaat tagtgagttg ttccggcatt tccggaaata
     2401 tcttctttat tttctactgc tgcttcaact gcataagtca aagaagaagc aatgtcttct
     2461 aaagacatag aaggcgtacc cactggacga tcgatcactt gatcgggtga gaatggcacg
     2521 tggatgaacc cacctcgaat tgccgggaat tgtgtttcga tcaaatgaag caaacgatac
     2581 atgatatcat tgcagacaaa tgttcctgct gtataagaga tgtacgctgg tagaccatga
     2641 tcttgtacat tttttgtcat tgctttgatt ggcaatgagg taaagtaagc ggctggaccg
     2701 ttttcttcta aagccgtatc gaatggctga tttccttcat tatcagggat tcttgcttct
     2761 gctagattga ttgcgacacg ttcgaacgag actgctgacc gcccacctgc ttgtccgaca
     2821 cagatcacga catctggttg gtgctgttgg atggcttctt tgactacttg actgcttttt
     2881 tcgaatacgg tcggtacttc cactttgatg atttcagcac cgctgatttc atctggcatt
     2941 ttttttactg cttcataggc tggattcact ttgtccccac caaatggatc aaaacctgtt
     3001 actagtactt tcatctgttg ttcctccgtc cgattgattt aacatatggt tatcttttat
     3061 cataccattt tccttgaaca gcgtaaataa aggaaacaat agtttaaata acataacaga
     3121 tcaaacttaa tatattctta taaaaaaata gtgttccact acaatgttag aagaggttgc
     3181 gacaattatt ctgtcacaac ccctctcttc tattatttaa atagaatcat ataagcaatt
     3241 tggaaaacta gcataaataa cgcaataaac aactggtttt tgatcactcc gtatttgtct
     3301 ttcatctcca gcatcgctac aggcacgata ttgaagttag cagccatcgg tgtcagcagg
     3361 gtcccacaaa aaccgcaagt caatgcaacc attcctatta acgctggatt cgctccatga
     3421 ctaaatacga atggtgcacc gatcccaacc gtcatcacgg tgatggccgc aaatgcattc
     3481 cccatgatta ccgtaaatat caccatgcca agagcgtaaa tgatgatgcc gatgttcaca
     3541 tttccttctg gaacgatcgt acctactgca ttggaaatca ctgtcccaac tccagcgctt
     3601 gtaaataccg cacctagaga agctaaaagc attggcaaca tgcttaacgg ccctactgtg
     3661 cccagcatat ctgctgcatc atctaaaaat gtacttggtc gattatctcg agaaaagaac
     3721 atcaagatta gcatggctgc aaaaacaccg acgcccacgc cgactaaagc acctaaattg
     3781 gtaaatagag caaacaagat cgcaaagaca ccgatactca aagctggaat aaaaattttc
     3841 attcctagtt tgtctgacat tttttccata tattcttttg atggaagccg gctttctcct
     3901 ttgctgactt tcttagcaat tgctggtatg gtcatcgcaa agatcaagcc accgttcacg
     3961 attgccggaa gccatcttcc tcctgcaata actaccccta agaccgtcca gaaaaaggct
     4021 gacccataac gatgaggatt ggttttatct gttaaatttc ttactccagt gtaaatcaat
     4081 acgagtccca tcacgatata aaggatctcc agtaatttat cgcctaataa aatatcagga
     4141 tttgtaaaaa agtccatctt attgcccctt tcctggataa tatttcttcg ctaatttctt
     4201 ttctttaaga tagaagtaga cacttgccac aactaaagcc gtgatagcca ctggaacttc
     4261 cactaaagca agctgtccca atgttacgtc atatcctaga tctttcagtg ttgattggac
     4321 tagcaacgcc cctgctcctc cgatgaatag tacttggcca aagaaccagc agacattttc
     4381 catagctgaa gccatacctt ttagttcttc ttcatgctta ggatggactt ctaacccttt
     4441 tgattcgatg gtccccaatg ccatcggtaa aatgattgga cgaacaaatc cagcaactcc
     4501 accaaaactc acgttaaaag ccgcaaagat cattcgaaag atcccataaa tatctacaat
     4561 cataccagca gatactttct tgaatcgctt gatcaaggaa gccgctgatt ctttcagacc
     4621 atttctttca agcgttcctg ttgccaacat aatgatgata aaaatcgcca tcccgcgatt
     4681 gtttacaaaa cttgtaccta aaagttctaa cattccttga atgccaagac cgccagtcaa
     4741 agctgtaaca actaaagcaa ccattacgat caatatcgag tctaatttaa atgcaaaccc
     4801 gagaataaca atcaagacgc ctaaaaggct aagataattt tccatatatt ttcctccata
     4861 aaatgacaat atttttttaa ttataaagca aaacacataa aaaatatagt tgttttctca
     4921 cgaaatagac actattttta aatatttttc gttatttttt tatcacaaaa attatcttac
     4981 ttattgtaag gtaaagcttt ttttaattta ttgcccgata atatatagaa ataaggtcta
     5041 gttactgttt tttttaaatg attaataaat aacaacttct ttctatgaaa ttgcaaagca
     5101 ttcatcttct tttccgctaa cgatatatcc gtcagtgctt ggtacacttt actaaaaagt
     5161 atgagattgc cgatatctgg ataggtgtgc tatactacag aaaaagatat acaatctgcc
     5221 accgggtagg ataaagagga tgatcattcc attaggtctt tgaagggatg attttcctct
     5281 ttttgtgtat ttttttatag ttaaggagga atgtaagtat ggcatggatg gaattaatca
     5341 tagcaggaat tttggaagta ttctggtcaa cgatgatgaa atggagtgat ggtttttcta
     5401 aaatcaatta ttctttttac acagtgattg gcatgattgc tagtttttac tttttgtcaa
     5461 aggcaatcaa aagtttgccg atgagtctct cttatcctat ctggacaggg attggcgcag
     5521 ttggttcggt cataattggt gtggtcttgt ttcatgataa gctgaatctt tccacttggt
     5581 tctttgtggg gatgctactc atcagtatca ttggcatcaa gattactagc ggccactaga
     5641 cacttggaat aagtactgat cagaaaaaat aagccttttt atttaatatt caattttttt
     5701 atgaaaaaat aagaaataag tccaatgacc tagcgacttc tccactcatc aggtgtatgc
     5761 ttgtactatc tatagaaaag gagtgaatat ttttgaaaag tctttcggtc caagaattat
     5821 ccaagaactt tggtcacaaa caagccctca gcgatgtcag ttttagctta tcccctggca
     5881 aaatcgttgg attagtaggt cctaatggcg ctggaaaaac aacgatcatg aaagctattt
     5941 taggactgat ccattactca gatggaacaa tctgtattgg tgaaaatgag atttctccct
     6001 ctagtcataa agggttggaa caagtaggag cattgatcga atacccgggt atctatccat
     6061 tcttaacagg ctatgatcat ctgaagttat tctctgaaac caacgatgta tctgctatcg
     6121 acactatcgt gaatcagctc aagatggaaa agtacattca caaaaaagcg aaatcctact
     6181 cgttgggaat gaaacaaaaa ttgggaattg ctcttgcctt actgaaccat ccgtctatcg
     6241 ttattttaga tgagccgatg aacggtttgg atccacaagc aacaagagat gtgcgaaaaa
     6301 tcattaccga cttggctact cagggcacct ctttcttgat ctccagtcac ttactcagcg
     6361 agcttgaaaa aatggtcgat gagctgatcc tgatcaatca aggaaagatc atcaaacaat
     6421 gtacaatggc tgaattgaac caaacagcgc aagatttcat cgttatctct acaacaaatg
     6481 atctagctgc tcgaacgatc ttgacagaag ctggatatac tttggaagat cctgataaaa
     6541 tcaagctttt aaaagaaaac gaagaattat taggaaccgt gatccagcta ttgtctgcac
     6601 aaaatatcca tgtgacagac gtccagcatc tgacgaatga tttggaatct tctctattgg
     6661 aaattctgga ttcagtaaag ggggaagaag aaaaatgaca ttgcttgtaa aacaagaatt
     6721 atttaaattg atcaagaaaa agtcaactgc tgttttatct gttctattag ttgttttgct
     6781 cataggaaca gcacttctag ccaaaaaata cacgacgatc attgatccag ttgaaatgac
     6841 tgctcagctt tttagtgcca catcttggat tgtctttatc atgattgcag ctgcaagcac
     6901 gatcatttcg atggaagcac aatatggtac attgaaaaat ctcctttatc gaaagtattc
     6961 tcgaggagaa atattagtaa gcaaatggat cacattagtt atttattctg tttatttata
     7021 ccttttagct attattgtca ctgtgttgat gaaactgatt cttttccctt cgatttcctt
     7081 cacggagaag gtttctactg gtcaaacact gatccaaagc ttgttcactt atactttggg
     7141 tagttatatc ggtttatggc tgattttaag tttagtgttg atgattgctt gctttatcaa
     7201 tagttccggc gcatccatct cagcaggaat cgtcttttat tttgcttcgt caatcatatc
     7261 tggtatcctt attgcactca tccaaaaatg ggagtggatc aaatggaatc cgatcagtat
     7321 gttgaatctg caaaaccaaa ttggaaacga agagatcatg aagcaattga ctcatctttc
     7381 tactaatcaa atgctattcg gtaatttagc ttacatcgtt ttgttcttag cattaggata
     7441 tctcgtattt aagcgaaaaa atgtatgatg actcatcaaa aaagaggctg tgaaagagac
     7501 gttcagcctt attgccgatt ggctgtctct taaacaccgt ttattctgaa aaaggagctg
     7561 tgacaacatt tgtgtcacag ctcctttcct agtatgtttt tgaataaacg acaggctcac
     7621 aacctctctt tatacttctt ttatacttct atacgtgaag catcccagtg gcaaataaaa
     7681 ccattgcaat cactccgacc atcgtcacac ctataagtaa aatcttatct aagtggatat
     7741 gttgtacagg ctcgttttgc tccttacgtg ctttgaggta aaaataaatg cctggcaaga
     7801 aaagaacaag aacaagcatt acttcattaa aggctacgac tagcatagcc catacttgaa
     7861 aggcacttgc taaaagccct actaaaaatt ggacccattc tttccgctga taagaaagtt
     7921 tcatttggta caatcctaag aaaagccacg tgaagaaaat agctgctgta ccaagtgtgt
     7981 aagcaaagtt ataagcactg tcagtgaata ataatgaaag taaaaagaca ttcgtacata
     8041 acgtcgtcaa tacgatagca taagttggtg ccccattttt gttgagtttt ccccatgctt
     8101 taggcaaaag tccgtcttca gccatgtttc ccattgtttc aatcggtaag atcgtccatg
     8161 agagccaaac accaactaaa gaaatgatca aaccgccgtt gatcacgact gctccccatt
     8221 taccaaccat catttcaaac acatagccca tagcaggctg cgccttgatc gtttgcagct
     8281 gattcatcgt cattgtccca tatggaagca tggaaaccaa gacgtaaata ataatcaagc
     8341 cgaatatccc tagaatcgtt gctttcccaa catctgattg tttttttgct cgtgaaccta
     8401 cgacagaggc tccttcaata ccaacaaata cccaaagcat caccatgatg caactcaata
     8461 cttgactgga aaacgggatc ggctgtccat tcgcattcaa tataatgtcg ctagaaaagt
     8521 tatcaatgaa ttgttggatc gaaaacgtgc tgatagctac tacaataaat aaaaataatg
     8581 gcactaattt acagaatgtg acgatagcat tgacgaaact agcattttcg actccccgat
     8641 tcactagcca tgcatatccc cataaaaaga ctgtactcat cacgatcgat gccagatttt
     8701 gcccaccttc aaatactggg aagaaatatc ctaatgcgct catcaacaat gttgcaaaag
     8761 ctacgttgcc taaccagcat gtgagccagt aaccccaacc gctgataaaa ccagcgaaac
     8821 ggccaaaacc ttcttctgcg taactaaaga tcccgccttt taaatctgga cgttttttat
     8881 tgatattatt gatcgacaag gagagcatca acattgctgt tcctacgagt acccaactga
     8941 aaatagctgg gccgccagcc gatccggaga tgtccgtcat aataccaaat acgccacctc
     9001 caatcgctga accaattact aaggcagcaa gtggaattaa accaattcct tttttctgtt
     9061 gctctgtatc catgtaagca tcctccaaaa taaaaccgct tttatcaaaa agtataacaa
     9121 acctttttta tttttactta attaataaaa actttaatag aaatataatt ctaccggctt
     9181 ttttctcatt atacaagcaa agcgcctagt ccctttccaa attacaccac caaaaaactt
     9241 aaaaaagatg ctatactaaa aggaaagaat tggaggatga tccatgaaca ttttatatat
     9301 atcgatttca ggaaatacgc gtgcctttgc caaacatcta gcagaatatg ctgaaaaaat
     9361 gcatgcagaa gatcctgtca atcctgaagt tactttaaaa gaaatccatg aaaatagtga
     9421 ttttacgaaa gaaacagaac cattttttac tttcgttcct acttatttag acggcggaaa
     9481 tggtttagat aacggtgata cagaaatctt gaccgaaacg atgcgtgaat atctggaaca
     9541 tgaagacaat cataaacttt gtcttggtgt agtcggtagc ggaaataaaa acttcaataa
     9601 tcagtattgt ctaacagcca aacaatatgc acaaacattt ggctttcctt tcttggcaga
     9661 ttatgaatta cggggaacac catctgatgt gacacgaatt tatcagattt tagcagaaaa
     9721 caataaataa taaaaaagaa gaagctgaaa aatagatttc agtttcttct ttcgtttcta
     9781 ttgtttctat catattaagc tttgacatcc atcacaggtg cttttgcttt tgctttacct
     9841 gttttttcca agacaaagtt ttttacacga tccatattgg ttaccaagac gatcatggat
     9901 gtttctttgc ctgctgcttt gatcgcttct aagtcagctt ctgctacaag cgtatcaggt
     9961 gtcacttgct gcccttctgt tactttcaca tcaaatggcg taccgcctaa gtcaactgtg
    10021 ttgattccca tatgaagcaa gatttctaaa ccatttggcg ttgtgatccc aatagcgtgt
    10081 ttcgttggga agacagagct gactacccca gtaactggag aatagatatg tccgttttct
    10141 ggttctacaa agtagccttc acccatcatc ttttgtgcaa aaactggatc acttgcttta
    10201 tctaaagaaa caactgttcc gtcagcaact gatgagagga tagtcacact ttcagctgaa
    10261 gtttgaggta ctactttttc aggcacttca tttactgtgg ctgtttcagt cgctaattct
    10321 tctttttcta aacggtcttt aggaataccg aagaagaatg tagcaacgaa gccaccagca
    10381 taagctgcca ataatccaag gatgtagcct aaccatttac cgtcagagat caatgggatc
    10441 aaagcggctc ctgaaggtcc aatagcgata gccccgacat ttccgatcat tccgatcact
    10501 gccccgccga tacctccacc gatacaagca gtaataaatg ggcgtcctag aggtaatgtt
    10561 actccgtaaa tcaatggttc gccgattcct aggatcccga ctggtaaagc tcctttgatc
    10621 atttctgtta attctttatc ttttttgcag cgaatccata atgccaatgc tgcacccact
    10681 tgtcctgcac cagccatcgc aagaattgga agcaatagcg tacgaccagt ttcatcaatc
    10741 atttgcacat ggattggagt caaaatttga tgcagtccga acataaccat cggcaagaat
    10801 aatgtgccta gaacgaagcc ggcaaatgct ccaccaacgc caagtaccca gttgatccca
    10861 ccgaccatgc catcagaaat gaaacctgct aaaggcatga tgaagaaaat ttcaatcaga
    10921 ccgatggcaa tcaatgaaag agttggtgta acgatgatat ctaccgcatc aggtactact
    10981 ttatgcagtt ttttctcaac gattgacaat agccaaacag cgaagatgac acctaggatc
    11041 ccaccttgtc cagctgcaag agcttcacca gtaaataagt ttttcagtgg tgcttccgga
    11101 ttcatccctg tcagcatcac aacggccccg ataactccac caagagttgg tgttgcacca
    11161 aaaacttgtg cagcattgat acctgtatag ataactaggt agctaaacat cccgtttttc
    11221 aagatgttca tcacatcgat atattgttgc catgttgctg catcaagtgt tccggctgtg
    11281 actaagtttg ctaaaactgc ggcaatccct gccacgatcc cagtaccgac aaatgcagga
    11341 atcattggca caaagatatt agaaatgtct tttaataccg atttgatttt agatggtttt
    11401 tgtttcgatt tttgtgccgc tttcatttct tgtgcccgtt cgtttacacg gtcttttcca
    11461 gatgctgatg aatttgctgt agctgtactt acagaagaaa gtttttctcc taatttcacg
    11521 cctgccaaat caaccatttg ctgtgctact ttgttcactt tcccaggtcc gatgatgact
    11581 tgaagctgtt catcttctac tacaccaagc actcctggaa tcgcttttaa ttcagagaca
    11641 tttacaagat catcattgat gatcttcata cgcacacgag tcatgcagtg gacaatgctt
    11701 tctacattgc ccatgccgcc tgccccttta taaatttgtt ttgccagttc ttccaaagtc
    11761 agttcgtttt ttgccatggt cttttccccc tcataaggtc ccttttacaa atccgtttgc
    11821 ttcagctaat tttgcttgag cttcctcttt atcactattt gtcaaaatca tgacgatagc
    11881 cagcttaaca ttttgatctg cttcttcaaa gtacttttca gctgtttcgt aatcagcttc
    11941 tgtcgcttgc atgatgattc gttttgagcg ttcgattagt ttttcatttg ttggtttgac
    12001 atcgaccatc aagttattga atactttacc tataccaatc atactgatag tagaaatcat
    12061 attcaagata agtttttgtg ctgttcctga cttcaatcga gtagagcctg tcaaaaattc
    12121 tggacctgca tcgacttcga ttgggaaatc cgcgtgttta ctgatttcgg cttgtttatt
    12181 gcaagaaatc gttcctgtga cagcaccgat cgattttgcg taatctaatc caccgatcac
    12241 atatggtgta cgaccgctag ctgcgatacc aataactata tcattttttg tcaaattcag
    12301 cttgattaga tcttcttgcc ctagctcata agaatcttcg gccccttcga cagctacagt
    12361 cattgcttct tctccaccag caattagacc tatgaccatt tccggttcta caccgaatgt
    12421 cggtacgcat tcagcagcat ctaacacacc tagtcttcca cttgttccgg ctcccatata
    12481 aatcagacgt ccaccttttt taaaggactc aatcgtgtta gcaatcactg gttcgatact
    12541 tgtcagttct ttttcaaccg cagcggccac tttctgatct tctttgttca ttagttgaac
    12601 ggcttgagaa atactcatct catctaatcc aaaagtttct tggtttctgc gttccgttgt
    12661 taggttctct aaattgattt tgctcatttt tatcttcctt cttttcttat aaattgatag
    12721 ttcataccag ctttgatttg gttgatcaat ggtagctctt ctttgataac tttagctact
    12781 acattcactt tttcatccgc tggcaaatca tatttggtta attggatctc acccatatag
    12841 cgcaaatact tttcgttatc taaagtaata gaccctttca tacgcgtagc tgtatttctt
    12901 gctgggatag gcggaatctc tcgaaaacgt gcatctacgc ttcgtatgac atctcttgca
    12961 tcgtcttgcc gattcgtatg cttccctaat atatattcgt aaaattcttc atctacaggt
    13021 tccgtatgga gcaagactgt ctgttctttt tggaaagaag caaattgctc ctgaacgttt
    13081 tctgacagac ctgcatctcc gatgtaaaca atatccgtgt tacttgctaa tagatctaga
    13141 gcgcctgcaa gaggatggat ccctcgatgt tcttccaaag ttggcaatcc ttgatatagt
    13201 gggcctctca actctgtatc tcctggtaca aaaccttgga caaggagacc ttgaattttg
    13261 agccattgat tttttttctg ataccattct ttgtccagcc ctgtttcggg acgtggataa
    13321 taattatgcc aagcttcaat ctgtgagaaa tcagcttctg cttctttcaa ttcatcgata
    13381 tctttaggcg tgatcgtgct agcattcaaa ctgattttca attgatgtga ccagtcggca
    13441 atctgctgat tggaaatatg ataatccatt cttaaacctg ttacaccaat tgctttcaaa
    13501 ggcgttagat cttctaatga aaaacccgct cgttccaatg cctctcctga aatatcgacc
    13561 atcaattcta gtttattctt tttcgcttcg cttcctagtt cgatcaatcg cttttgatat
    13621 gccgaaacat catcttctgg tatatgcatg gaagtgaaaa taccgacaaa gccattggat
    13681 gccatttggc ggatatactg tttcttctct tctgacaaag aatcgttcat aaatattgaa
    13741 aagccaaaca tattatccct ctttttctgt atccgtcttc atttctatga ctagagtata
    13801 tatctaaaga aacaaaattt caatactttt attaaaataa ttaaatttca tttctaaagg
    13861 ttgagtttat attatcaaaa gaattgtcat aacctaaaaa aggcactgct aagcaaaagc
    13921 agtgccttga aatattttat ttaaataaca caaaaacata attactcata agaaaccaat
    13981 tctgtattat ctaccatgaa tgtaaagaac ccctcattag gcatcggatg aaaataagca
    14041 ttgatcactc ttatcaaggc attatggcaa actaacagat agacattttc ttcgtcttcg
    14101 atgcattctt tcaataaagg aacgatccgt gcatacacat ctaagactga ctccccattt
    14161 gggaatcgta cagcgaacgc taaacgtgct ttttgaaagt tctcatcttt gcttggcagt
    14221 ccatcataat ccccaaaatc catttctacc aatcgttcat caacggtcag cggcaagctg
    14281 agacgatcag caactgcttg tgctgtatct cttgctcgtt gaagagggga atggatgatt
    14341 ttcgtgattg gaacaggcaa atctactacc ttttctgcta gtttctgtgc ctgcatctgt
    14401 cctttttcag tcagcggcac atctgcccgt ccgcaaacta atccttgtgc gttccaagtt
    14461 gtttctccgt gtctcgttac ataaagcatg tgattctctc cttcgttggc aaagttcccc
    14521 ttaaccatac cttgttgttc ttgagattac aagggttaga ttctctcaag agaaataatc
    14581 tcagtagata ctttatccag gaaggtttga tcatgttcca ctagtaacat ggcaggtttc
    14641 acgttcaaga tcagttgttc taattgttct tgattgaaga catccaaata attcaatggt
    14701 tcatcccatg tatatagttc agctggctgt gataaagatt tagccaattc cacttttttc
    14761 cgttggccca tactcatctg ctcgatcttg ttatgaaaaa catctctttc catcccaagc
    14821 tttcggaggt tgttcaaaaa tgcttggtag tctacttggt ttttctctgc aaattccgcc
    14881 aacgttcctc gattgtcttc ataattttgg cttgcataac taatgctcag atgttttggc
    14941 tggtattttt ctcctataac cttgccgttg aatgccccca gaagataatg gataatggat
    15001 gactttcctg caccgttagg acctgaaatc gccacccgct gatgaggctc gattgtaaaa
    15061 tgaattggct cgaataacag attttcatac cctaattgaa gatcttctac gcttaaaagt
    15121 cgcttatggt gagacgcttg gctattcatc gtcaaagaat cgatatattc gatatctttt
    15181 aatagttttt ctttctcgct gatctgggtc tccatccgat tcacgattgc tttggatcgt
    15241 ttcatcgtcc gtgcagcatc agcacccact gctcctttat tcactcgtct agattcagta
    15301 tcgatgaatc cgacttgttt ctttgtttta tctccttctc gggaacgaga ccattcggct
    15361 ttttcagctg ctgttttctt tagcctactg acttcttttt tcaatttttc attttgagcc
    15421 atttcaaatt catcacgaag ttttttctgt tcttcataga tagagaaatt cccttgataa
    15481 agttccagtt gacttttttc gattgctaaa acatggtcca ctacttcatc gataaatccc
    15541 cggtcatggc tgaccacgat gaagccttgt tttttctttt tcaaataagc cgctacttgt
    15601 tttctaccag agatatccaa atgattcgtt ggttcatcga ttaacgggaa atgagtgtca
    15661 tccacaaata aaagtgccag taggactttt gtcttctctc cccccgatag tgtgctgaat
    15721 tctctccata agatttcagg atctgtttgc atcaattgga gctctctttc gatttcccat
    15781 atctcaaaat ccgtaatatc atttaacacg taataggtta aacgttcttt atcttttgtc
    15841 tgttgcggga aataggcaaa ttcttgctga tggattactt gcccttgata aggtagtttg
    15901 ttttgtagaa tattcagtaa agttgtcttt cctcgaccgt ttcgtccgat aagtcctagt
    15961 ttccattgtg tgtcaaaatt tagatttgct tgttcaaata ataatgtgcc ttggctgtcg
    16021 tagccgaatg tcagattttt tatttcgatt ttagacattt tccatcacct cgtaaaaaaa
    16081 gaccagtcct attttcagaa ctggctaaag aggatgcaag ggttggatac acacaaaaag
    16141 acccatacat cgaaaaaacc aagccaatcc cgaaaatctg cacactgctt ccttgtctcc
    16201 acaaggtaca gtctgaatgc agctttcatc aatcgactta atttttcaat gcacggatcc
    16261 ctcactttgt cctatatttg aaattacgat agcataaaga aaatgatttt gtcaactact
    16321 tcgggaggat ggtgaaaaat ctgctaagtg tctgtcctaa gatttttgtt ttttctaatg
    16381 tttgcctgtg ttccattgct tcttctaaac ctattggacc caaatgaata cttaagacaa
    16441 ttgggagaaa atcagaaagt ccttctagct cttggtctct acttccgcaa atagcgatta
    16501 ttggttttcg atattttttt gcaagcactg ctacaccgta tggaactttt ccgtggatcg
    16561 tttgctgatc gatccgccct tctcctgtaa tgatgacatc tgcttgttcg atcttttttt
    16621 ccaatccagt gatttggctg actaaatcga aaccagaaac catcttcgct cccaacaaaa
    16681 aaagggctcc accaataccg cctgctgctc cacttcctgg aatatcatct aaatccacct
    16741 cccagaaatc ttttatttgc tgagcaatct ttcctgcttg tttatctaag aaagctagcg
    16801 tcgtatctat tcctcctttt tgtcttccaa attgccaagc agctccttgt tgacctgtat
    16861 atggattggt aacatctgca gcgataatca attttacttt agaaacaaga acgtttcttc
    16921 gatcaaaatg aagtttttta gtagataata aaggatttcc ttctgtgtac ccttctaaag
    16981 aagcacccaa ggattggagt aatcctagac caccatcgct acacccgctt cctcctaaag
    17041 tgacaataat ttgttctact tcttgaagca gtgcatcttt aataagttct cctaaggcat
    17101 aactggaagc aagtcggata gtttgatccg ttggtttatc aagtagatct aaccccaatg
    17161 cttgtgcaga ttcgatgact gcggtgtttt ttccttgcca agttgtcaat aaatagctga
    17221 tttttcgctg acggaataag agatccatcc catcaatggt acgccatgtt cccctgagcg
    17281 cgtaatagat tgcttctgca gtattttctc cgccatctgc aatcggcaca ttgatttttc
    17341 ttcctttacg atcttcccag ccatttagaa ctgcctgatt tagttcaaat gaagaagcac
    17401 ttcctttaaa tgaatcaatt gccgccaaaa tatccatctg tatccctcac tttcttctta
    17461 agtaagacac tttttttcat ttttttcaaa caaaacaatg ctattttctt ccatttttct
    17521 atatactaaa agggaactca ttgaataaag gagagaaaaa acatgaaaat cgcaatagct
    17581 ggggccggag caatgggcag ccgaatcgga ttgatgctac atcaaagcgg aaatgaggtc
    17641 ctcttgatcg atcgttggcc tgctcacatt gaagccattc gtacaaatgg gttgattgct
    17701 gactttaacg gtaaagaagt ggtcgcaaaa ctgccaatct attcaccaga agaaatcatc
    17761 gaaagcaacg aacacgtgga cttgatcgta gcattaacaa aagccaatca attagatgat
    17821 atgttttgtt cgatccaatc cattattact gacaatactt atgttttgtg tttactaaat
    17881 ggattaggtc atgaagatgt actggaaaaa tatgtgccaa agaaaaatat cttatttggg
    17941 atcacgatgt ggacagctgg tctagctggt cccggaaaag tcacattgtt aggtgatgga
    18001 gaaatcgaac tagagaactt ggaaccagaa ggcgaagcat ttacaaaaaa agttgtagaa
    18061 gtctttcaag aagcaaattt aaatccgatc tatagccata acgttcgtta ttccatttgg
    18121 cgaaaagctt gtgtaaatgg aacattgaat ggtttatgca cgattttgga ttgtaatatt
    18181 gctgaactag gcgcgcaaaa agcggcagag agcatggttc gaacaatcgt atctgaattt
    18241 gcttctatcg cagcaaaaga aggaatcata ctagatcaag aagaagtgta ccaacatatt
    18301 gcttctactt atgatcctga caacatcggg ttgcattacc catctatgta ccaagacctg
    18361 atcaaaaacc atcgtttgac tgaaatcgac tacatcaatg gtgccatttg gcgaaaagga
    18421 caaaaatatg atattgctac accatattgt gcctttttga cccaattagt ccatgcaaaa
    18481 gaaggaatcc ttggcgcaga ataaaaggct ctctgatgag aatcagctga atcagcagct
    18541 ggttctcttt ttttaagccc aataaaagat caaaaagaaa acacaactct catgatgcca
    18601 taagaattgt gcttgtttgt ttcagtacat aatctcttca aaatgtaggt tttttatttg
    18661 ttttcaacag aggagaggtc atattcgtat tgctcataaa tagtggaatc gttagtgata
    18721 aatcgttttg cccaattttc tgcatcataa aattccaata gctctgatag gattggctta
    18781 aatggtgtat gcagaaattc cggtaattca tctaaatcac gttctcgaag caaaaaaata
    18841 ttttcaggac gataaaaatg ataatgagca atcgcttgat tatccgtcac tagtttcttt
    18901 tgaaaataca tggattcaaa tgtccgcaaa gtcactcctt gctgaccctc ccgcaacagt
    18961 tccagaatcc cgcgcgattc ccctgttttt ttcaggtact cttcataagt aagatatcca
    19021 ggttgttcat tccctcgatg tggaagaatg aaatagttgg tcgtaacatc tctttttata
    19081 aattcctgct tatagctttc tgctcgttct tttctcccat tattcgttgc accaaaaaat
    19141 agatccgtct ttggttcgct agaagaaaaa ttcatatgtt tcgaataaaa tgaactatta
    19201 tgtttcagcc caagttcttt tgcttccaaa aaatcaaaat gataaatctc atcgattgcc
    19261 ggttcatctt gtgcctgctt cagcatcgcc tcgtgttctg ctttgaagtg attccaaaaa
    19321 aataacacaa tttttgcatt ggtaaatggg cgcacgcgtc gagccatctc catatcaaat
    19381 ccataatcta aaaaaacgat cagctgataa tttgccaact gttgtctagc tgatttaatg
    19441 aattccgact gtagtaaatc ttttccggac caaacatcta aagagcggat ggaaggcaaa
    19501 aaataaagtg atttattttt tgcaactagc agtacgtcat ttttgttcat cttttccgcc
    19561 tcactttctc tgtcactttt tcctatgata gcctgtttaa atagtaaaaa gccagtaaaa
    19621 cgtttcctat atttgtatga aaatttaaca tttgtatgaa aatatgatga aataaatcat
    19681 tcttctatta aaattcgcct aaaagttttc tgaatagttg taattgtctg aaaatttgtt
    19741 atcattagtc attgttaaat attgctattt attcttaata taaattttga ttgtgaattt
    19801 aaaagaaaga ggtcatttat ggaagataaa aaattgaaaa aacaacttag ctccagacat
    19861 atcaccatgt tagctttagg tggagcaatc ggtgcaggtc tatttaaagg aagtggcgaa
    19921 gcgattggga tcgccggccc ttctgtattg attgcttttt tgattggtgg gctgatttta
    19981 tatatcgtga tgaaaggtct gggaaaaatc gttttaagcg gtggcgacac gcatcacgga
    20041 ttatctggtt tgatacgccc ttatctaggt gctcattctg ctgattttac tgattgggtc
    20101 tactggtcta tgtggattat caatatcatc gctgaagctg ttgcagctgc ttcctttttg
    20161 cagttgtggt tcccgcacat tccagcctgg gtatttgttt ttatgttggc tgttttaact
    20221 acgatcatca atctttattc ggtacggtta ttcgcagaaa cagaatattg gctggctttt
    20281 gctaaaatca gtgtcattat cttactgatc atttttgcta cttatcttgt cggtcagcaa
    20341 atgttgggca caggcgtttt ccctaccctt cagcaattga ctgaccatgg tgggtttact
    20401 cctcatggta tgaagggaat catcagttct ttgcttgtag ttatctattc ttacggcggt
    20461 tctgaactga ttgctatcac ggtaagcgaa gcagatgatc ctaaacgtgc gattcctaaa
    20521 gcaatcaaag gtgtcatggg aagaatcatt tccttttaca tcattccttt gtttttgctt
    20581 ttgattcttt ttccttggaa tactttagca ggcacgaatg tcagtccttt tgtgatggta
    20641 tttgaaaaaa tgaatatccc atttgcagcg gatatcgtca attttgtgat tgtccttgct
    20701 ttgttctcat ctatcaattc gggtgtgtat gcatcttcaa gaattttgtt cttccgtttg
    20761 aaggatcgaa aaggttcctc tagaaaacta gctgttttaa acaagcatca agtaccgcaa
    20821 cgtgctgttt tattttgtac cagtgttctt tatcttggtg tagctctttc ttattttgtc
    20881 ggtgacaaat tatttggcta tctggcaggt tccctttcgt atacagtatt attgatctgg
    20941 atcattatca gtgcggcatc ctttgtactg gcactaagaa aaggaacatt atgggataaa
    21001 ggaatcagct tttttgcatt agctgtctta ggattgattt tccttggtat cctgttcacg
    21061 aactccattg gggtaactgt attgactggc ctgctttacc tgttcattta tttcagttat
    21121 caaaaaaaga atgatgcgtt cgtattgacg aatgaatgaa atcgatagaa aattttattt
    21181 tatttatgtg gaatagatgg agctattgaa gaaaggagtt gtgacaaaag tcttgttgca
    21241 actccttttt ccgaataaac agtctcatga cctcttggta aacggtgttc aaaaaccctc
    21301 tgtgcaaaat aattgattgt tctccatgct catgacatga tagaagaaag gaatgaaaaa
    21361 aaggagtttg ttttaaatga aaaagtattg gaagtttttg ttgatgatcg gtgtttcaac
    21421 ggtagttatg tttggtatga tgtacttgaa tgtctatgcg ctcgatcata tcttcttcag
    21481 tcgtacacga gtattcatgg cgttgatgat gggtgcagtc atggcagtca tcatgctgtt
    21541 gttcatgtgg aaaatgtatg aaaacaaaaa gataaatgtt atgatcttag ccgctagtct
    21601 tcttgttttt gccggttcct tgtttatggt acgaagccaa actactgtca acgacacagc
    21661 ttggatgaag gccatgattc ctcatcattc tatcgctatc ctggcaagta aacgagctga
    21721 tttaaaagat cctgaagtaa aaaaattagc ggaagaaatc attcaggcac aagaagaaga
    21781 gatcgacaaa atgaaaaaaa tgatcaaaga aatggaatga ccattatccg tccaaataaa
    21841 aaaagaggat gttccagaag ttatcagctt caagaaataa gaagaagcta cttctggaac
    21901 gccgtgaata aggggttgtg aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca
    21961 aaaatagctt ctcctatttt tcgtttggtt aggcttatta ccgcagatgc aagcttttga
    22021 acaccgttta ttaagaggtt gtaaaatcag cgttctgacc tgagtattag agagacaaat
    22081 ggaaaaatag ttcctcatat tttgccattt tttgagctaa taccgagggt cagctgattg
    22141 aacaccgttt atcgagaggt tgtgaaaaag tcgcttagtt tcgcgtatta agaaaaattt
    22201 tgtgaaatgg ctttccacat ttttgtataa atttggctta ataccgagaa actggctttt
    22261 gaataccgtt tattcgtaaa agggattgtg acaaaagtct tgtcacaatc cctttttatg
    22321 tttttattgt tctaattgcg ctgtcttgct tactgcttct tgcggtttca caaatttttt
    22381 tgagattccc caacctgtga aggcactgac catcgaaaac acaggagaaa gcaaactgaa
    22441 aaatacgaat ggcaagtaag tgagtgtagg aataccaaat gtacttgcta cgaaacttcc
    22501 ggcaattccc caaggcacta agtagttgat tactgttcca ccatcttcta gcgttctacc
    22561 taatacagtt ggatcaaatc ctgctttttc ataagtttct ttaaatgcat taccaggcag
    22621 aataacagat aggaattgtt caccaataaa aatatttact ccgatacttg tcatcaatgt
    22681 tgtaaaaatc aaatttggtg tgttcgtcat ctttcttgat actcgttcca tcacggttga
    22741 gatcaagcca aattcgatca acaatccacc taatgacaaa gttagaataa tcaatgacac
    22801 agtaggcatc atactttcga ttcctccgcg gctaagcagt gaatcgattt gttggtttcc
    22861 agtatttgaa acaaaccctg attcgatgac cccagccaac ttcgttaagg aagtttgtgg
    22921 gttttgaata aaaatcattc ctactgctac agcgatattc aacaaaatcg ttaaaattgc
    22981 cggcaccttt ttccatgcac acagtaacat taaaaataaa ggaatcagtg accagattga
    23041 aatagtaaag tttgcttcta gaacatcagt cacttcacga atagatgaaa gacttgcggc
    23101 tttacttgtg tgtcctaaaa tcatgaataa aaagaaagaa acaacaaatg ccgggacagt
    23161 tgaccacatc atatgcttga tgtgtttgaa caaatcggca tcaacaatag ctgctgctag
    23221 atttgttgat tcggataatg gagacatctt atctccaaaa acggcacctg aaacaatagc
    23281 tccaacaacc agcgctggat ttaagcctag tgttgtccca ataccgaaaa atgcaatccc
    23341 aatcgttgac ataacagtaa aggcactccc tacagcgcta cctacgattg cacacacaac
    23401 aaatacagaa gggacaaacc actggacact gatcaatttg aacccaatga ccattagagt
    23461 tggaatgatc cctgcttgta tccatacagc aatcaatgaa ccgactaaaa taaaaataaa
    23521 gattgggatg attcctggtt tgatgccatt gatgattcct tcgtgcagcc aatctgtcgg
    23581 gtatcttttt atcactgcat acaacatgac cattccgatc gctgctaaga tcgtgatatt
    23641 aggtgagacc tttaatccga caacgccaat cgcaatgcct aaaacaataa ccattaatac
    23701 aagtgttgct tctaaaaaac ttggtgttcc tttttttccc atgataatct ctcctttttt
    23761 agttgttctt atgttctaaa aaagttaaga tatcggatta ctccgccgca attcatccgc
    23821 gattcctcct ttataaaaat aaaaagacct gttttaaact aaggacgaat gactccgcgg
    23881 taccacctta attaaaaaca gatctgtttt tcactttcaa acttttattc aaatgtatgg
    23941 actttccatg taattcgtca attaggcttg atcggttcac agcgaccacc gactttctga
    24001 acaaaacacc taaccgctac tgcgtgaaaa gttgacttgt acgaagttta ccttccataa
    24061 gatcatttgt caatgaaaaa gaaaatattt tttcattttt ctgaaaatta tttttataac
    24121 tttcacacac aagattattt tttactagaa agtagcgccc tcttgttttt ttcttgctac
    24181 tatttcttga tgttcttgct tgattctttc taatagcttt ggctctttca acagatcaag
    24241 agctgtattg gcgagtagtt ctgctgcaat cgcaatagaa gcaaggcctt tgtcactttt
    24301 agcagcagct ttgaattctt ctgtgtgtcc ggcaatatat gtctcagaga ttgctaccgt
    24361 aggctggatt gttggtatga cttggctgac atttcctaca tcagaagaac cgagacttgt
    24421 tctttgttcc gtttctattt cttcatctgg aacacctgct tcttttgcat gctggaagaa
    24481 taagtcatca aaagaaggag taacgatgac atcatcaact gcattttgga acaatccaaa
    24541 ctcaaaagtc gtgcccgtac ttatcgcagc acctcgtacg atattttcca ctttttcata
    24601 tactttatct aatgtttgcc gatttcctgc acgtaaatag aaacgtccag cagcgtaatc
    24661 tggaatgacg ttggcagcta ctcctccgtc tgtaatgatc ccatggatat tgacatcttt
    24721 tggcaattgc aagcgtagag cgttgattcc attaaacact tggatcaatg cttccaaagc
    24781 atttactcct ttttcaggtg ctgctgctgc atgggaagcg acaccgtaaa atttgatgtc
    24841 gactggatca ttcgctaaag attctgtcgt tttcccataa cgaaaagctg gatggacgca
    24901 taacgctaca tcgacatcct caaaaaaacc ttctcgaaca aagctgcctt tagctgatcc
    24961 gttctcgccc ccttcttccc ctggggtgcc atatacacgg atttctccac cagtttcatc
    25021 aatgaattgc ttcactatgc tggcggctaa tacggagtaa gtaccaaaca aattatgccc
    25081 gcatgcatga ccaatacctg gtaaagcatc gaattctgcc aaaaaggcaa ttgtgggacc
    25141 gggtttattg gaaatataac gtgcatcaaa ggctgttcgg tgtccagcta cttctttttc
    25201 tacccaaaac ctttcttttt ctaattgttt aatcaacgct gctgaggaat aaaactcata
    25261 gttacttact tcaggatgtt cgtggatatc tagagcaagt gcttgatatt ctggtaaacg
    25321 atattggatt agatccttca attggtttgt tgagattgtt gttgtcataa aaaattcctc
    25381 ctatgctagt catttttctt attttctccc gaatgtttcc catgcaggca cgcttgatcc
    25441 ttttgatgtt ttctcgatta ctttgactgt gtcttctgtt tgataagcgt ctactatttt
    25501 ttgatacgtt ttattgtttt catcttcttt tcttgcaacg atgatattca cataaggacg
    25561 tgcatggtca tccactggtt ctaagaagat ggcatcagaa gcaggattaa atccagcatc
    25621 tacagctaca ccgctattga tcactgaaat gtctacatct gacaaagcac gtgctgtttg
    25681 ggaagcatct aattcagaaa tgtctagatt ttttctattc tcggtaatat cagaaacagt
    25741 gggcgcttgt ccttttgcct tatccacttt gatcaatcca gcagtttgca ataacagaag
    25801 agctctgccg ccatttgtaa catcattagg gattgctact tttgctccgt ctttgatatc
    25861 agctacatcc ttcaaagtgt tagaataaat tcccagcggt gcattgacag tatttccgat
    25921 cgatactaaa tcagttccgt gttctttatt gtaattgtct aaaaagaatt gatgttggaa
    25981 agaattcaaa tcaatcgatc catctgctaa agccacattt ggttgattgt aatctgtaaa
    26041 tttcacgtat tccaaattaa tgttctcctt tttcaaacgg tctttcacgt tgtcccatac
    26101 atctgtatct tctccaataa tccctagttt tacgatagtt tcttttttgt cagttgtatc
    26161 tgcttttcct tggctacacc ctgccaacca aataattgct acaaatgtaa tgactacaaa
    26221 acgaataatt tttttcattt tttctcctcc actttcaatg tgtaattttt ttaatcagtt
    26281 gattactgat aaattgactt aaaaaaacta agattagaat caataatgta gccacaatcg
    26341 ttacatctgt ttggaatcga ttataccctc tcgatatagc aagattccct aatccgcctg
    26401 cacctactgc tccagccatg gtagtcagtc cgatcacgtt gatgatagtc aacgccgaga
    26461 cccgaatgat accaggcaaa ccttctaaca aatacacacg taaaatgata ccgattggac
    26521 tggttcccat cgcttctgcc gcttcgatca ccccaggatc aacttctagc agtgcgttct
    26581 cgatttgacg agcaaaaaac ggaacaactc caaaaatcaa tggcactaaa gctgctttcg
    26641 caccaatcgt cgttccaact aagaaacgag tagtcaatgc taaaagagaa agcaagataa
    26701 tgaaagggat ggaacgaatg atattgatca gcttatcaag tatttcaaat agcagacggt
    26761 tagctagtaa tccattaggg cgtgtcacta ctaacgtcac acctaagatg attccaatca
    26821 tcccgccaat gaatgctgtc caaaaagaca tatatagtgt ttgcttcgtc gcttcgacaa
    26881 attcatccgg aatcaaataa acattgggca aatatgtttt aaagaaatca gtcattttat
    26941 cttcctcctt cgatcacttt gatacgacta tctaaatcgt ttttttgtaa aatatttatt
    27001 tttacaccag atttgatcaa ataatccaat gcttttttcc gctgtttggt ttctccagct
    27061 aaagtaacga tcaaactccc taacggcgtt tcttgtaata actctacatt gccatataaa
    27121 atattcgctg ttacttgata tttgctgtac agatgagcga ttagaggttc gttcgtctga
    27181 tttccaatat aacttaattc caccagccat ttattggcga tctgatcggc aaaagcagaa
    27241 tgggcaatga tcgtttctaa tgcttggtca agatgagtag ctgttcgaat aaaatctttg
    27301 gtcaattctt cttcaggatt gctgaagatc tggatgctgc tacctttttc aacgattctt
    27361 ccatcttcca taaccgctac cttgttgcag atttctttga caacttgcat ctcatgagtg
    27421 atcaggacga ttgttaaacc taactggcga ttcaattttt ttaacaatgc aaggatctga
    27481 agggtcgttt tcggatcaag tgcactggtt gcttcatcac ataataatac cttaggttca
    27541 ttcgccaaag ctcgtgcgat tgctactcgt tgtttttgtc cccccgacag ttgtttagga
    27601 taagcagatg ctttttcttc caaaccgaca agttccagta gttcattcac tttttgacga
    27661 cgttcctgtt tcgattttcc agaatacttt aaagaaaaat caacgttgtc aaaaatagtt
    27721 cggctttcca ttagattgaa atgctgaaag atcataccga tggcctttct ttcttttcgc
    27781 aattctttgg gagagagctg actcagattc gtctgattga caatgacttc tcctgctgtt
    27841 ggtttctgca gcaaattcat cacacgaact aacgtacttt tccctgcacc tgagtaaccg
    27901 acgattccat aaacatcgcc tttttcaatc gttaaatcta cagaatctac tgcctgtatc
    27961 tctttttctt tttgtttgaa acatacagaa acatctcgca attcaatcat taaaattcct
    28021 ccttatctaa aaaaagcgtc ctcaagaaaa tgaaaatgtc attttcttga ggacgctttt
    28081 ttgcgtgtta ccacctcatg ttcaagctgt gttcacacac aactcctctt caagtacgat
    28141 catactctag caagatatcg gtcgcagccg tcatcgcctt acatctatgc tcgggatgaa
    28201 ttgctcgatg gccattttcc aatagtcgtt ccttgcttct tctcagctac cgaagctctc
    28261 tgtcaaaggt tcttctatcg tacttaccat ttcaatgcaa ataatattca aaaaaaaagt
    28321 ccttttacta acataaacta tgtcagtaaa aggacgacgt atcgcggtac cacctttttt
    28381 cggaagtttc cttccctcaa gcccaacatc tcaaaaagag agattggcgt tcgttttaac
    28441 ggtcgaacag ttccgaattt gcctacttat cgacaaatta ttctccaagg ccattttcag
    28501 cttttcttac ttgactcttc tcaccagcca gagcctctct gcaaagtttc caaacttact
    28561 ttccttttca acgaaatcga tattttgttg ttgggattaa tctacatgag gaaaactgaa
    28621 aagtcaagta cgaaattcaa attatttttt ctatatttat ttttctgttt ttttatttaa
    28681 catttcaata acagttcgaa gatcttttcc ttccgcaaga agtttcaatt tttccttttc
    28741 ttcgacggta taatttcgga caaaactgga atcaggtatc aaaacaacgc ctaatcctgc
    28801 tcgtgaagca gctgttgctc ctactaaaga atcttccact gcaaaggctg aactagcttc
    28861 taatcctgtt cgttccaaag ctgtcagata aggaatcggt gaaggcttgt tctccgacac
    28921 ttcgtctccg aatgtaaacg tgtccaagta atcagctaat ttaaagtgat ccaagatatc
    28981 tgttgctctt ttcgtaacag tggtcgtagc aatgcctagt ttcatatgac gttcttttaa
    29041 gtctgccaat atttcttttg catatggttt taagtggatg gctccgcttg tcagctgttg
    29101 ataaaaatat tcttcacgct tcgctcggac ttcctgtact ttttcagggc tacctgctgc
    29161 tttcactaaa atatcaaaac tttgtttcca gttttttccg ccccaagcgt caacgatttc
    29221 ttttgggata tggatatcaa attgctgaaa tccccaaagc cagccatcac gatacgtttt
    29281 ttctgtgtca actaacaaac catctaaatc aaatattgca cctttcatct atacattaat
    29341 cctttccaaa acaatacaca tagtttagca cgactggtcc aaaaagaaca gaagcaaaga
    29401 accagccttc tcgtttataa gagttcttgg aatcgacgga tatagatttt cttcacagct
    29461 gtcacaagcg ccagataagc gatgactgta gcaaataacc ataaccagta attgccagga
    29521 agtggcatca agcctaattc agcaccaaaa cttgtaaaag gaaggacaga accgacaata
    29581 attcctaatg tagtgataac aaacatggca aatgttgcgt tgctttggat aaatggtact
    29641 ttcggtgtac gcagtgcatg gagcactaag gtttgtgtcc atagtgattc gacaaaccat
    29701 cctgcatgga ataatgcgat gaaaatcact cgctgtgaac tatccaatgt atggaaactt
    29761 ccgcccacta cagcaggaca aataacaaaa tacatcaaca agtaagtagt aatatcaaat
    29821 atcgaacttg ttggaccaaa gtaaaccatg aattccccaa tactagatgc attccatttt
    29881 tttggctcgt ccaaatattc tttatccatc cgatcccatg gcaaggaaat gcaggaaaca
    29941 tcatagatca gattcaaaaa caaaagttgt aaaggcagca ttggtaaaaa tggcaggaac
    30001 gtacttgcaa tcagcacgga aaacatattg ccaaaattag aacttgctgt agccttgata
    30061 tatttcatga tattcccaaa agtttctcgt ccagaaagaa ggcctctttc caaaatcgtc
    30121 aaatcttttt ctaaaaggat cacgtctgca gattctttcg caatatccac agctgtatct
    30181 acagaaatac cgatatcagc cactttcatt gcaggagcgt cattgatacc atctcctaaa
    30241 aatccgacag tatgaccatt tttacgtaaa gctgtcgtca aacgtgcttt ttgctgagga
    30301 ttcaatttta cgaatacttc atggtcttca gctacttgtg ctaattcatg atcactcatt
    30361 tccgagattt tctcaccggt aaccaattca ttgatctcta gacctacttg acggcacact
    30421 gaacgtgtaa ctaattcgtt gtccccagtc agaactttta cagctacacc atgttctttc
    30481 agagctttca acgcttgttt cgttgtttct tttggtggat caaggaaagc aagataacca
    30541 atcaaaacca tgtctgactc atctttgact gaaaattctc caacgacgct tggattggtc
    30601 ttttgtgcga caccaatcac tcgtaagcca tcttcattaa gtgactgtac ttttgcaagt
    30661 acggcttctt ttcgttcttt tgttaatggt gtaacagtac cgccaagatc aataaattta
    30721 gaaatgttca gcatttcttc aatcgcacct tttgtgatca tttgtgtttt accagctgga
    30781 tcagcaacca caacactcat acgacgacgt tcaaaatcaa aaggaatttc atccactttt
    30841 tgataattga tcttatctgt atctaaagtt tctgttgctt catcaatgat agccacatct
    30901 aacaaatttt tcagccctgt ttgatagtag ctatttagat acgcatggcg caaaacacga
    30961 tcatcttcat ttccttcaca atccatatga tattcaagaa tgattttatc ttgtgtcaat
    31021 gtccccgttt tatccgtaca taacacatcg attgcaccaa agttctggat ggcattcaaa
    31081 tttttgatca ctgttccttt tttggccatc acacttgctc ctttgaccaa attcgtcgta
    31141 acgatcattg gaagcatttc aggtgttaga ccaactgcta cagatagtcc aaaaagaaaa
    31201 gcttctagcc aatccccttt tgtaagccca ttgatgacga taactgctgg agccatcaat
    31261 gacataaatt tgatcagtag catggatgtt ttatggatgc ctaattcaaa gcttgattga
    31321 attggttttt cagatagcgt ttctgctaca tgaccaaata gtgtttcatt tccaacagaa
    31381 acaatgattc cttccgcact tccactgatg acattacttc ccataaagac aagattttcg
    31441 taacttgttt cgctttgctg atcgtcttca catactttcg catgcttttc tactggatag
    31501 ctttcccctg tcaatgctgc ttgggaaatg aataaatcct ttgcggacaa taaacgcata
    31561 tccgctggta tcatatcccc tgctgaaagc cgaacaagat ctccacagac gatttcttcc
    31621 ataggaatct ctgtgtactt tccattacgt tttacagctg ccgttacttt cacaagtgat
    31681 ttcagttttt cagccgcttg attggaacgt acggactgaa tcaacgtcat tgtcccgctg
    31741 acgataacca tagtgaagat aatggctaca ccgaaaagat ctttatctcc aggagctgct
    31801 aatacatatt ccgtgatgaa tgaaataatt cctaatgcga tcaacactaa tgtaaatggc
    31861 gtgatgtatg ctttcaatat ttctacaatg aatggtgttt ttttgccata tgaaatcgca
    31921 ttttcaccgt aattttctct tgaacgttcg atttgttctt ctgtcaatcc atttgctgat
    31981 gcatggaata gttcaaataa ttcttgtttc gtttttccag caaaagctgc atagattttt
    32041 tgtgtatctt tctttttttc catctcaatc tctcctttgt gtccaaaaga cagctgttct
    32101 cgctgctttt ggtctttagc tattcatcgg atcgatagag aaaaaactga aaggggctga
    32161 gaacagatag ataatagccc tggcctttcc tctagatcct tgtttttcga atgactgtca
    32221 tccatttgtt ctcatctcct ttactaagta attttaattc atgacttcca atcatttttc
    32281 gaatagttat ttttccaatt agaccacctc ctttttattt ttcaccgatg gggatttgcg
    32341 gcaacaaaaa aacctctcgc caaatactca gcgaaaggtt tgaaaaagca tattaaaaaa
    32401 agcttctcag atctcatcgt tgagttttga cactgtacaa cgtaaaaagc agatacctgc
    32461 ttttagctac cttatgaaaa gccttatctc gacaattcct gttctaccca ttggcgtctc
    32521 tcgacgtttt tgggcagtag cctatgtttg tataggagcc tcacctaaca aatcttattc
    32581 ggttttcctt cgttaatata acaactaaaa aagaggatgt caaatcaatt ttccatgttt
    32641 ttcatacttt ttttaaaata cacacgttat attcctgtct cacgcggttt tatttgtctc
    32701 attttccacc tcccgctata atagaaatat agtaggaaac gaggtgctgt tatggaaaga
    32761 acacttgtta ttatcaagcc agacggcgtg agacgccatt tagtcggaag catcatccaa
    32821 cgttttgaag caaagggact ggccattgct gaaatgaagt ttgaaactat gactcctgaa
    32881 ttagcaaaag aacattatca gcacttgact gagcgcagtt tttttgatga actgatcgat
    32941 tacatgactt ccggtcctgt cgtttatctt gtgctggtcg gcgaggaagt gatcgatatc
    33001 gtccgtaaga tggttggagc aacaaaagct gccgatgctg ttccaggtac gatccgagga
    33061 gactacgcgc tgccggggac tgaaaacatc attcacgctt ctgattcccg tgatgctgcg
    33121 gtaaaagaga tcgcccgctt tttcccgcca ttcgatataa acaaaccgtc tgaaaaagcg
    33181 gcgaagtgat acaaattcta aactgctggt ctagttgctg ggttcagcaa tggccagcag
    33241 ttttttctct aaggacctcc gttgattctt tcctaacata tattcgagca ctgtgaagaa
    33301 ttcttggtag tctttcgtct tttcttcccc taaagcagca gaaatcaatc tttgataata
    33361 atctgccatc aatgtttcat agatcactgt acttctttct ttatgtgcta agctccgttt
    33421 catatcttca ttcacactac gtgccttttt caaccgacca ttttctatat aaaacgaagt
    33481 caggttcatt aaaaaagtaa agagatactg ctcatgattg ttcaactgtg ctaatcgtcg
    33541 cattcttttt ttgattttca aataattgtt ctcaatgaac cgatcactga atatccaagg
    33601 aaaatcagct agaatagata gttcaaattg accatagtct ggtatctgca tcaagtattc
    33661 ttcaatgatt cggcattcat aacgtaaaaa ttcaaattct gtctcagata cttctgtttt
    33721 ttcgaccatg tgaagattca aaaccaaata atacagatct tctgttttct taaaatgcct
    33781 acggttattg ctgatctctt tataaggatc aaagctgtct tcttgtaccc gatctagcat
    33841 tcgtcttttt ttctttaact ttattggttc atccagctgg tttcgcatcc attcatattc
    33901 tgcaagtgtc atgttcattc gctctaaaaa tgatctcaat gttacaaatg acattttttt
    33961 cactgaattt gtctcaatcc cgactagaga agtcttaaaa cagattcctt ccgctaattg
    34021 ggactgtgtc aacttcttgt tgactcgaag tttcttgatc aattcaccat catacataat
    34081 agttctcctt tttaatttaa atttttccac attcaataaa tagatacgtt aaaaaggaaa
    34141 aatacacgaa aaaaataaaa aaatgttttt ttcataaaaa ataccaacct tcaagcatta
    34201 gaatgttgtc taactactga aggttggttt gattgtttat tgattatttt tttgctgttc
    34261 aacgtctgtt cttgttactg gatataagtt ggttgttgtt ttattaccat tttttgaaaa
    34321 gacacttgtc gaatgttcgc ctttttgctt ttcgattgct tcattacgtt ccgcttcatt
    34381 tttatagtca tattttttcg gatcaatcgt ctcaaatccg tttggcacat aaaaccgcaa
    34441 gagattttcc tgattcagct tatctgaaag acttaacgca gtcttgactt tttcctgatc
    34501 tttggagatt tcctcatcga ttcctgctgc tttcgtatcg atgatttctc ctgtctgatt
    34561 attgtaagct tttcctccta ggacggtgta tttgggtgtc acaaagttcc catttcgaaa
    34621 agcaactact tgatcatgct gagaagataa taagtctgta ccaaaatgaa gataatcttt
    34681 atcatcgatt cccaatagat gtagtaatgt cggcaaaaca tcgatttctc caccgtattc
    34741 atgattgact gtccctttag tataaccagg catatggatc atcaatggca ctcgttgcat
    34801 ctgtgcgttg tcaaattcat cccatgtatc tggatcttta ccaagagcgc ttgctaaatc
    34861 tttattatct gtattcgaga tcccaaaatg atccccgtaa atcacaaaga ttgaattttg
    34921 gtaaatacca gattttttca aatacgtaaa aaattgttcc aatgattgat ccagataatg
    34981 tgccgttcga acataattat ctactgtgct attgccagta ttcaaagatg gaaagtcgaa
    35041 attcttgtca tccgtataat aaggcgtgtg gttggttacg gaaagaaatt tcgtgtaaaa
    35101 cggctgttgt agatgctcaa gatattgggc agattctctg aataaatctt tatctaatat
    35161 cccataacct aacgtttcgt cggattcatc aaaataagat cgatcaaaga aattgtcata
    35221 acctaagttt ttatatacat gatctctatt ccaaaaacta gctacattcc catggaaaac
    35281 agcgcttgta tagccttgct tttgtccaag gatcgctggt gcggcttgaa agacattgtc
    35341 tgacccaagt tctgtgaata atgagccttg aggtaaacca aatgtgccag tttccaacat
    35401 attttcagca tcacttgtct ttccctgtcc tacttcatga aagaaattgt caaagctgat
    35461 cgttgcttga ttctggaaaa tactatttaa aaacggtgtg acttcttgtc cgtctacctt
    35521 catattaatc aaaaactgct ggaaactttc taaatggaga acgatcacat ttttcccttt
    35581 agcgatccca aatgtttcgg gatttggctc tgcataatgt ttctttgtat aatctaaaac
    35641 ttcatcaatc ccattactgc ttgcatgcgc gcgaacactg ctagtcattc ctgttttgat
    35701 tccgtcataa atagtatacg catcgattcc tagatatttg acaatatatg aacggtcaaa
    35761 tgttcgctgc agcaattgtg gacggttggc ttcgctcagc gctagatttc ctgaaaaaat
    35821 aagccctgaa agacaggtaa cagcgatagc catcggtttg ccgacagggt tgcttttgat
    35881 aggtattttc ttgaccttca accaaaccag tagcccaatg aacacagcga tatccagcca
    35941 gtagatgaca tcatggggct tcatcaaaga aaaggagctt cctgacaatc cttgcgacac
    36001 tttcgaaaag cctaatacag atttgactgt aatgaaatct gtgaattccc gataaaaaat
    36061 aatattcaag tacaacaaaa gcgtatttaa aatatcaatg atcaaaagaa tagctaacgc
    36121 tggctttggc tttttaatat acaaagaaag gccaaaaaac aataaggtag tcgcaattgg
    36181 gttgatccac aagataaagt actggatcgt accttccaca cctaatgaaa aatctgcata
    36241 gtaggcaatg atcgtcttca gccagaaaaa gaaaacagct gtcaaaacga ttgctaaacg
    36301 attttggcac aattttttaa gttgtgtcac gtatatcact tctctctatt cacatttttt
    36361 cttattttgc tcctgaaaaa tgaaaatttc ctaaaaaagt tgttatctta agattttttt
    36421 attctttcta aagattattc cgtccacttt tcacagcata aaaccgctgc gatgtaagcg
    36481 attaaactaa tgaagagata aaagtcttgt ggtgaccgct tcactccacg gtattcaaaa
    36541 gccagtttct cggtattcgt acaaaaaaag aggctgtgac aaaattcttg tcgcagctcc
    36601 ttatttcttg atgcaggaca gctttttcac aacttcttcc ttaaacggtg ttctcctgcc
    36661 aactcctcgg ccacaagtca caatatttat aaaacatgag aagctgtttt ttgaaattgt
    36721 tccttgtggc tcagagttaa acggcaggct caagacctct tgatacacgg tgttcaatca
    36781 gctgaccctc ggtattagat tatgtcagga cgctaatttt acaacctctt ggtaaacggt
    36841 gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac gaaaaatata aggagctatt
    36901 ttttgaaatt gctccttgtg gctcagagtt aaacggcagg ctcaagacct cttgatacac
    36961 ggtgttcaat cagctgacct tcggtattag ctcaaaaaac ggcaaaatat gaggaactat
    37021 tttgccgttt gtttctctaa tactcaggtc aaaacgctga tttcacaacc tctgtttttc
    37081 attgtccata ggattgatat tgtccttgtg atgactcatt cgtaataatt gaggcttgat
    37141 tttcttcact tcccgttatc gtttgtccac tgccagaatc tgaaggactt gttcctgtcg
    37201 actcgttttt ttgagaagag acagttgttt tcttgacttg ttcatttgtc tttttccatt
    37261 ccgctaaacg atcggcgacc acttttttgt ctactttttc agaataagcg gtgatcactt
    37321 ttccattttt caaacgggct actttgtcgc catcatgagt caaaagcaaa acggtcaaat
    37381 gcttgtcttt aaattgatat tgtctgagag aaatcgcact aagtacgtca tcgatattaa
    37441 taaattgatt ttcttctttt ccttttggca aataaatgtc caattcgcct ttttcgtaat
    37501 tggcagttat tttatactcc gcccaccaat aagttgagaa ttcttttttg aaattatcta
    37561 ctgattcttt gcttgctacg attttttctg tttctttctg agcaagatct gctgtcattt
    37621 ttcctgaaaa tgctgcggat aaaataagca gtaagaaaaa accgaataac caaaagagaa
    37681 gaaacggtct ttttttcctc atgctttcct ccactcctat ttaattttga ctattctatt
    37741 atatacaaaa aatgaaatag aaagacaaaa aagttgaaaa agatcgtaaa taattgaact
    37801 tctttttcac aaaatggtaa gaatggagaa tttcacgcat ttgctctcaa ctattctttc
    37861 ttaagcctca aatccgtttt tatctgatac gtctttgaac caatgacccg attttttgat
    37921 tgttcttttt ccatcttgtg ctaagtctac tgaaataaag ccatatcgat tcttatatgc
    37981 attggtccac gaccagttat ccatacatgt ccacatatga tagcctaaac aattggcacc
    38041 ttcttgaatg gcttgatgga catatttcag atgagattgg acaaattcga tccgataatc
    38101 atcgtggatc atgccatctt ctttgataaa tcgtgcttcg ttttctacac ccataccgtt
    38161 ttcagaaata aagcagtcga tatttccata atgatctcgt acattgatca aaatatcata
    38221 gattccttgt tcatagatct cccatccgcg ataaggattc attttacgac caggcatttc
    38281 ataattgtcg aaataatcct caggcattgg accgttttta gtatcgattg gtgtttcttt
    38341 tgcttttacc cggcgtggct ggtaataatt gatacctaaa agatctactg tattttcttt
    38401 gataaccgtc aaatcctctg catggatcac aggcatgaga tcaagttctt ttactatctc
    38461 aatcaattca cttggaaact cgccttttac agctggatca aggaatgaac gattgaagaa
    38521 cgcatctgct atttgcgctg ctttaacatc ttcagggttt gattcgtctc ttggatagct
    38581 tggtgtcaga ttcaagatga taccaataac accaccttgc tccatttcat ggtaagattt
    38641 gatggctaac gctgaagcca acgcttcatg atagccaact tggatcgctt ttttcatatc
    38701 tgactcttct ggataatgcc atcgatataa ataacctgct tcgactggaa cgattggttc
    38761 attatgagta aaccattttt ttactttcga accaaacaat tcaaaacaac ttttggcata
    38821 tttttcatag gcttcaaccg tttctcggtt caaccatccg cctttttctt gcagatacat
    38881 cggcatatcg aaatgataca gattcacaaa gggttcgata ccgttttcaa tcaactcatc
    38941 aaaataacga tgatagaaac gaacggcttc ttcgttgatt gttccagatt catcaggtat
    39001 caaacggctc cattggatag atgttcgaaa tgaattatgc ccagtctgtt tcatcaactg
    39061 tacatcctct tgatacttcg tataaacttg cgaggttttt tcaggtccta cttgatcaaa
    39121 gaacttttgc ggttcttttt tgtaccaata atcaaaaatg ttctctcctt ttccatcgcc
    39181 tgaaatcctt ccttctgttt gtgggccact tgctgcagaa ccccaccaaa aatttgctgg
    39241 aaattgatat tttttcatca aagcacctct ttttcttttt tagttcgttt tagttgattc
    39301 catgtatgat attttccatc acaatcactt tttcattttc ttcctcttct tttttgattc
    39361 gttttaacag ctgttctgct gctcgttccc cgattttatc tgttggtggc gtgatcgtga
    39421 ttttcggaag gatactcaga tcgtttttat ctaaataatc atagtgactg aacgcaatat
    39481 ccttcccgat tctgacacct tcttgattga aacattcgat ggcaccaatc gacatattgt
    39541 aattgctgac aaaaatagca gttgcccctt tttctaataa tgcttttgcc ccgtaatagc
    39601 cgctttttct agaatagtct cctgtaaaga cctctaattg gatcgatgga tcattttgga
    39661 ccgcttcttt ggctcctgct aaacgttctc ttgctacgta gtctgtttga gtggcagcaa
    39721 taaatccgat ttttttatgt ccttgttcac catgatgagc gatcactttt gctacacttt
    39781 ctcgatcatt cactaatatt gtatcaatac ctgctggtcc ttctggacaa ttcaatgcga
    39841 taactggaat actcattttt gtgagcattt caaatccaga ccactcttct tcggataaga
    39901 agacaatcag cccatcgatc acatgcttca tcaggtattc aattttttgt tcaatttttt
    39961 ctggctgatc ggcaaacccg cttaataata agctataccc attttcttca gctactcttt
    40021 cgatccctga gacaacttcc gacccaaaac ggctggaaat cccgtttatc aaaagtccaa
    40081 tagagaagct tcgattattc ttcaaccctt tagcaatgat gttttcttta tagtccaacg
    40141 ctgaaatcgc ttctgctatt tttttcatgt tcttttcctt cagttgctga ccattcaagt
    40201 aacgggaaac tgttcccact gaaacaccag ccatcttagc cacatcacgg atcgatgcca
    40261 tacattctca ctcctgccag ttacatttga tttctctttc ttgttgttcg attatgatga
    40321 ccgcattctt tgcatagtgt tgcttgtcat caatatccat ataactaaag tcttcagtag
    40381 agcaacttcc tctcactatt aattatactt aaacaagtat ttgaaccggt tcatttttaa
    40441 tatagcattt ttttaaaaga ttgcaacact tttttaaaac gctttctgaa agtggcggat
    40501 tttttgcctt tttaaaattt tattctaaaa tttactctat ttgtgggtgt tttgtgcgtt
    40561 tttctcttcc atccgtttga agttttacat tccaatggta taatttcttt atcctatcaa
    40621 atgggggaag tattttgaag aaattaatcg tactatttat tttgtctgcg ggacttttga
    40681 cattgactgg ctgtgatttg tttggcggct ctgaccaatc ctcggacgaa acaaccgatt
    40741 cttctgtctt aaaagcggaa aaagcagata ccaccaacag tgtatatacg ctaaaagtac
    40801 gtaaagatat ggatttatcc gcgggacagt tgacatttac agataaaaaa atggaatgga
    40861 cacgcacgta tcagacacaa ggaactgatt cttctgaatc atctgaagaa aaaacagtgc
    40921 tgacagatat caagatcact accaaagatg acgaatatat tatttcagga aaagaaaata
    40981 aaaaagaaac aacagtcata tttacaaaaa tcggtaatta ccgtttgaag gatgaggatg
    41041 gcaacatcta cagtctatag tgccgtctgt tggatcttct tttgtttctc cccttctttt
    41101 ctgctatagt aaagaagcaa gatgattgta aaggagacga aatggatgat cgatagtcct
    41161 gattattgta catgtaataa caacaaaaat atccatacag aatttaatga ccaaggaagc
    41221 ttgagcatat gcgacaactg tcacaaacta gtcaaagatt catttaaaac atttgaatct
    41281 tatcctgttc aaaattatgt aaaaagtaga agaagataaa caaatccaag caaaactcac
    41341 tatggctgat ttttatgaac ttcaaactca gcttcttcct ttgatcaagc ttcatcagta
    41401 aaacaaacag tggatcattt cagtttacaa atcaaagagt aaagatttat ttatttcaaa
    41461 tatttgaata taaaataacc aaacgataga aaggcttatt ctacatcacg tagtaatt
//
LOCUS       DAMEEU010000018        40832 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.018, whole genome shotgun sequence.
ACCESSION   DAMEEU010000018 DAMEEU010000000
VERSION     DAMEEU010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40832
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.018"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            23..646
                     /locus_tag="PB779_000970"
     CDS             23..646
                     /locus_tag="PB779_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738510.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            1096..2145
                     /locus_tag="PB779_000971"
     CDS             1096..2145
                     /locus_tag="PB779_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0738511.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            2142..3023
                     /locus_tag="PB779_000972"
     CDS             2142..3023
                     /locus_tag="PB779_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738512.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            3026..3796
                     /locus_tag="PB779_000973"
     CDS             3026..3796
                     /locus_tag="PB779_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738513.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            4075..4929
                     /gene="aroE"
                     /locus_tag="PB779_000974"
     CDS             4075..4929
                     /gene="aroE"
                     /locus_tag="PB779_000974"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HDE0738514.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            5107..6270
                     /locus_tag="PB779_000975"
     CDS             5107..6270
                     /locus_tag="PB779_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDE0738515.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGVQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            6387..6797
                     /locus_tag="PB779_000976"
     CDS             6387..6797
                     /locus_tag="PB779_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDE0738516.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            6971..9199
                     /gene="topB"
                     /locus_tag="PB779_000977"
     CDS             6971..9199
                     /gene="topB"
                     /locus_tag="PB779_000977"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDE0738517.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGHLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            9370..9654
                     /locus_tag="PB779_000978"
     CDS             9370..9654
                     /locus_tag="PB779_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738518.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            9814..10050
                     /locus_tag="PB779_000979"
     CDS             9814..10050
                     /locus_tag="PB779_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDE0738519.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            10047..10445
                     /locus_tag="PB779_000980"
     CDS             10047..10445
                     /locus_tag="PB779_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDE0738520.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(11112..12056)
                     /locus_tag="PB779_000981"
     CDS             complement(11112..12056)
                     /locus_tag="PB779_000981"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDE0738521.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(12352..13296)
                     /locus_tag="PB779_000982"
     CDS             complement(12352..13296)
                     /locus_tag="PB779_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738522.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            13517..14731
                     /locus_tag="PB779_000983"
     CDS             13517..14731
                     /locus_tag="PB779_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0738523.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASIYGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            14753..16768
                     /locus_tag="PB779_000984"
     CDS             14753..16768
                     /locus_tag="PB779_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-rhamnosidase"
                     /protein_id="HDE0738524.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEETFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(16851..18224)
                     /locus_tag="PB779_000985"
     CDS             complement(16851..18224)
                     /locus_tag="PB779_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDE0738525.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(18250..18534)
                     /locus_tag="PB779_000986"
     CDS             complement(18250..18534)
                     /locus_tag="PB779_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0738526.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(18536..20551)
                     /locus_tag="PB779_000987"
     CDS             complement(18536..20551)
                     /locus_tag="PB779_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDE0738527.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(20730..21035)
                     /locus_tag="PB779_000988"
     CDS             complement(20730..21035)
                     /locus_tag="PB779_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HDE0738528.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(21124..22155)
                     /locus_tag="PB779_000989"
     CDS             complement(21124..22155)
                     /locus_tag="PB779_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0738529.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            22362..23237
                     /locus_tag="PB779_000990"
     CDS             22362..23237
                     /locus_tag="PB779_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDE0738530.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(23389..24231)
                     /locus_tag="PB779_000991"
     CDS             complement(23389..24231)
                     /locus_tag="PB779_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDE0738531.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(24323..26200)
                     /locus_tag="PB779_000992"
     CDS             complement(24323..26200)
                     /locus_tag="PB779_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDE0738532.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     RPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEATIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIDNQTNTPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDHETSGTYAYVLYDG
                     DKEIDPTNYSVTEQTNGFTVSVDSNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(26197..27618)
                     /locus_tag="PB779_000993"
     CDS             complement(26197..27618)
                     /locus_tag="PB779_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HDE0738533.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQAATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQTEIAKNGA
                     SSGTFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKAPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGISTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(27621..31010)
                     /locus_tag="PB779_000994"
     CDS             complement(27621..31010)
                     /locus_tag="PB779_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HDE0738534.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNSWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKNLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            31267..32658
                     /locus_tag="PB779_000995"
     CDS             31267..32658
                     /locus_tag="PB779_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738535.1"
                     /translation="MEKIIRILSISDKWMTKKELAKRIGSSESTFVRYIEEIKIRWGT
                     DVTIQSSQKLGYRLEHLNVPAYLNVLMEMSQSSTNSRLLNEIIVNPGKTIEYYCEKIS
                     ISRSSFTRKLKQCNQILESYLLKVIVDQGFQLTSLKSELQLRIFVTFFFLSYYGRRTL
                     PFPIEKKKIKEIMVKNNCQMNLFQEESPYEQSFFIMYFVVHLMRESQGTPFEWKAGDS
                     YVQLINIDKKDFLILKNLLGKLKYSSYIKVVNYFVNTIFSEFSEKEKNEISEQIRKNM
                     SYCSFSSADCKEKNEEYVVQLLTQIYFFSRIFPYDTTHLTIRATYFAQQMQHRQIRLY
                     AGFRAELQFYSTLLNQNLIYYLSSYIFWMLIGNPEIHHYTSDKKILIISDLSLRHSQY
                     IEEYISDILAVHKIHSETTAITEDQLSKYNLLEYDLIVTNQPILNAHVPHILIDDSVS
                     FANEEELIRLFEL"
     gene            complement(32731..33378)
                     /locus_tag="PB779_000996"
     CDS             complement(32731..33378)
                     /locus_tag="PB779_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDE0738536.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(33386..34072)
                     /locus_tag="PB779_000997"
     CDS             complement(33386..34072)
                     /locus_tag="PB779_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738537.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(34078..35151)
                     /locus_tag="PB779_000998"
     CDS             complement(34078..35151)
                     /locus_tag="PB779_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738538.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            35373..36047
                     /locus_tag="PB779_000999"
     CDS             35373..36047
                     /locus_tag="PB779_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0738539.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            36052..37392
                     /locus_tag="PB779_001000"
     CDS             36052..37392
                     /locus_tag="PB779_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0738540.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(37541..38527)
                     /locus_tag="PB779_001001"
     CDS             complement(37541..38527)
                     /locus_tag="PB779_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HDE0738541.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            39251..40282
                     /locus_tag="PB779_001002"
     CDS             39251..40282
                     /locus_tag="PB779_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0738542.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            40391..40816
                     /locus_tag="PB779_001003"
                     /pseudo
     CDS             40391..40816
                     /locus_tag="PB779_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
BASE COUNT        12667 a         7424 c         7669 g        13072 t
ORIGIN      
        1 aggagaaaaa gtagaaaaga aggtgtttgt tatttgggaa gtagttaaat cgagagtaca
       61 agaaatgaat gaacatttct cagtgtcatt cgcagaaaat ccaagtaagt attttcgacg
      121 tcttgttttt ctgctcatct tatcattgct gttaacagtt gcaatgtttt tattgccgga
      181 aaaaatccga gaagagcaag taaatagtct cgtttattcg tccataccaa ccagcaaatt
      241 gaaacctttt gattacagca aagctgatca gaaaatcaaa caaagccggg cgatatcggt
      301 gatgttcagc aaaccgaacg ggaaaaccta tcaggacatg cttgatgttt ttaatgatcc
      361 tgagcttatg gaagaattga atcgaccgat cttttattat ccgatcgttt atgatgtaca
      421 tgaactggaa caaaaatata acatacgaac ggatgaagtg acatttattt tctttgatgg
      481 aggaaaagaa gcaaatcgga taactgcggg taagggagga ataactgatt ttgataagga
      541 gttgatccct gaactgaatc gacttccgtt agccaatatc aaacaattag aagaagaatt
      601 ggatagaacg ggagtaactt cccaaaattc cgagattgct aattgagaca ttggcgcgat
      661 gaaacggtgg gtctatatag cgctattttt aattatcaga acaagtgatg tttgatcttc
      721 aaaataacaa ataaaaaatt aaaaaatata gttgacgaaa ttcaaaaatt cgattagact
      781 taaatcaatt cttaaggaaa gggtgacctg taatgaactt atcaaaacgt atttcagcag
      841 aaaacaaaaa aaattggcgc agctggcgta gataagttgt attaatggtg agactttccc
      901 atagatacaa ctttttagag tgcatttcta aagcttgtat ctatgctaga catgaacatt
      961 gactgccgca tagattagaa tctatgcggt tttttgtgta aagacaatga ccgctttggc
     1021 cattgtcttt ttttgtagac tggatacttg cctgattata ataaataaaa agattgactt
     1081 tgcaggagga aaaaaatgaa aaacaaacga ttaataacag ttgtagtaat tattttagtt
     1141 tatttagcag gtgcatttat ttatggaaaa gcctcaggcg aaaaagaaag tacttcgacg
     1201 aaccagacaa aaaaaacaac agttgttggg gtattgcaat acgtgagcca tccggcatta
     1261 gatgagattt atcgaggaat caaagatggt ctgaaagaag aaggattaaa agaaggagaa
     1321 aatcttgaga tcaaatttca aaatggacaa gccgatcaga gcaagctagc cacaatgagt
     1381 caacagctag tacaatctga tccagatgcc ttgattggaa tcgcaacacc tgccgctcaa
     1441 tcattagcaa acacgacttc atcgatccca gttgtgttag gtgctgtaac ggatcctgtg
     1501 ggggctggat tagtcgcttc tttagagaaa cctggtggta atgtaacagg tgtttctgat
     1561 cagccgcctg ttacttcaca aatcaagctt gcttctgatt tgttgccaaa tgcaaaaaaa
     1621 gtcggaatct tgtatgcttc ttcagaggat aattcaaaat accaagtagc acaagcagaa
     1681 gaagctgcaa aaaaagaagg gttagaatca gtaaaatatg cggtgccttc cactaatgag
     1741 attgcacaaa cggttcaagt gatgagccga caagtcgatt ttatctatgt tccattagat
     1801 aataccattg ccaatgcgat gcaaacagtg gtaaaagaag caaacaaagc aaatatcccc
     1861 gtcattccat ctgtggatac aatggtggaa caaggtggac tagcaacaat cgggatcaat
     1921 caatatcaat tagggcttca aagcggtaag atggcggcag aacttgcgag tggaaaagaa
     1981 aaaccggaaa cgacgcctgt ttatacattt gatcaagggg atacagtgat caatcaatct
     2041 caagctgatc gcttaggaat cattgttccc caatcgatga aggaaaaagc caaaatcatt
     2101 acagatgact cgcagcaaga aacatctaag gaggatgaca aatgatcgta tcagctattt
     2161 cacaaggcat gctttgggca atattaggat tagggatttt catgacttat cggatcttag
     2221 actttcctga tatgacgaca gaagggtcct tcccattagg tgctgctgtc tgtgtgacag
     2281 ctattactca tggggtagcg ccgattgtag ctacattatt aggcgtaggt gctggcatga
     2341 tagcaggact cgttacgggg ttactttata caaaaggaaa gataccggtt attttagcag
     2401 ggattttagt gatgtcagga ttgaactcag ttattttgtt tgtgatgcga acaccaaatc
     2461 tttctttatt gaatcatccg attctacaag acagcttcca tcgctttggg ttacctgatt
     2521 actttgacac agtccttctt ggcttcatct ctttgggcat cttgattgct gtactgctat
     2581 tcttcttcaa tacagatttg ggtcaaggct atattgcgac aggagacaac gaaacgatgg
     2641 ctcggtcgtt agggataaaa accgatcgta tgaaaatttt aggtttaact ttgtcgaacg
     2701 gtgtcattgc attatccggt gcgctgattg cccagaacga cggatatgca gatgtaaata
     2761 aagggattgg cgtaatcgtc atcggtcttg cttccatcat catcggtgaa gtgatcttcc
     2821 aagaattgac gctagcagaa agattgattg ctattgttgt cggcagtatc atttatcagc
     2881 tattgatttt agtagtaatc aaactagggt ttgacacgac ttatctgaag ttgttctccg
     2941 ctatcatctt agctatttgt ctgatgatcc cgcaattgaa gaaagcactg aacttaaaaa
     3001 cgggttttga gaaggaggca tagtaatgac tgatatattg acaatcaaaa atggcagaaa
     3061 agtcgtaaac aatggaatga atgaagagaa agtactattg gatgaaatta accttacaat
     3121 cagagaaggg gacttcatca ctgtccttgg cgggaatggt gctggaaaaa gcacactgtt
     3181 caatacgatc gctggtacgc ttcaactcag tcaaggatcg atctctttta aagatcagct
     3241 gatcacaaaa gattcagaag aaaaaagagc acgattcctt tctcgagttt tccaagaccc
     3301 caagatggga acggctcctc ggatgacagt agcagaaaat ttgctacttg cacaaaaaag
     3361 aggtcaaaaa cggaaattcc gtttacgtaa cttgaaaaat caaaaagaag attttttcag
     3421 actatgtcaa gaagtcggta atggcctaga gcaacacttg gatactccag cgggtgaatt
     3481 atctggtggt caacgccaag cattaagctt gctgatggcg acgatcacag ctcctgagtt
     3541 actattatta gatgaacata ctgcagcttt agatcctaaa acagctaaag cattaatgcg
     3601 attaacaaat cagcggatca atgaacaaaa attgacttgt ctcatgatca cgcatcgaat
     3661 ggaagacgcc ttgaaatacg gaaatcgtct gatcgtactc caaaaaggga aaatcgttca
     3721 agatatttct gaaaaagaaa agcaacattt gacaatgggc gaccttttgc agttctttga
     3781 agaagtagtg gattgatttc gacagaaaaa ttcctttcag tagaaggact tgaaaactca
     3841 ttgacatctt cctttgattc atcctatact taaaacaata aacaattaaa catatttggg
     3901 tgttttgtag gatcacgtag tcaatgattt taacaattaa atagaatatt ctttgctctg
     3961 acaagtaaac gatgagaaaa gaatttgcta ctttgccacc tagacgtttc gtactttttc
     4021 gtatcaaacg ctaagtggct ttttttattg aagtaagaac aaaggaggaa taagatgatt
     4081 tctggacaaa ccaaattagc tgggctcttt gctgatccgg cttctcacag tttatcccca
     4141 ttgatgcaca atactgcttt tgaagcaaac aacatcgatg cggtgtattt agctttccaa
     4201 gtaaatccaa tgaatttgaa gcaagcagtc gaaagtattc gaacttttga tatgttaggt
     4261 gtaaatcttt cgatgccgaa taaaacagcg gttattcctt atctggatga ggtaagccag
     4321 gaagcgcaat tgatcggagc agtgaatacg atcgtgcacg aaaagggtcg tttgattggc
     4381 tataataccg atggtgcggg cttcatgcaa tccgtgcaag aagctgggat ttcgatcaaa
     4441 aagaaaaaaa tgactctact gggagctgga ggtgcagcaa aggcagtcac tgttcaagct
     4501 gcgttagacg gcgctgagga aatcgtagtt tataaacgaa acaaccaaac attcgctcaa
     4561 gtaaaagaaa cattcgaaca actcagctat cgaacttctt gtaagataaa agttcgtgac
     4621 tttgccgata cgcatcaatt aagaaaagac ttgaaagaaa gctgtcttct agtcaatgca
     4681 acagatatcg ggatgggaaa gaaaatcaat cagtcaccgc tcttagatat aagcatgatg
     4741 catgagaatc tagcggtttt tgatttgatt tatgcaccta gagaaacacg tttattaaaa
     4801 gaagcaaaaa aagtaggagc aaaaggatac aatggacttg gcatgttgat ctaccaagga
     4861 gcaatcgcgt ttgaattatg gacaaaggaa aagatgccga tccatgtgat tgaaaagctg
     4921 tttgattaaa aaaggataat agataaagat cttttattct cgcataaacg gtctcaagaa
     4981 aagtaatcct ttatgtatcg aagcatttat ttcgttattt tttattaaat tatcaaaaaa
     5041 tgataggctt ttgtcgattg gttatcgtat cctttattta tcagtaagaa acgaggagga
     5101 accacaatga gtcggatgga tcgctataag gacatccata agaaggcgaa acctctgaag
     5161 cgggatacgg ggagtatttt tgctagaaga gaacgaaaac gaacgcgtat ggaaaatgag
     5221 gaagatgcta cccgtattta tgaaagagag cagcattcat ttgaacattt gaaccaatac
     5281 gagcaacaga tatacagaga tgcaccaaga gcagaagaac aacaaaaaaa taaaaaattt
     5341 ttcaatcggc aaaagaagaa caaaccgtta aaacctcgaa gaaagcgatc gtggaaaaaa
     5401 atcattctat cgattttgct tgttttgatc ctttattcag gtatctcatt ttttattggt
     5461 aaatatgtag ctgaacatga cacaagctta gaggcagcga cttcagaaac ctttcatggg
     5521 caaaaagcga cgaatggtgc gcataatatt ttgatccttg gaagtgatac acgcggagaa
     5581 gatgccgggc gagccgatac gatcatggtc ttacagttgg atggtccttc ccataagccg
     5641 aaactgattt cttttatgcg tgacagcttc gttacgatcc caggggtagg acaaaataag
     5701 atcaattcag cttatgcata cggaggagcc gatctagtgc gtcaaacttt agtagaaaat
     5761 tttggaatcg attgtcaata ctatgcgaaa gtcgatttca aatcgtttga aaaagtgatc
     5821 gatgccttat tcatgaacgg agtgaagatc gatgcagaaa aagatctgaa tctggatggt
     5881 gtagatatta aaaaaggggt ccagaagatg gatggacatg ttcttttgca gtacgcacgt
     5941 ttccgaatgg atgaacaagg agactttggc cgtgtcagac gccaacagca agtaatgaac
     6001 gctattttca gccaattgaa gaatccattg aatctgatcc gtgcacctta tgcagctggt
     6061 aaagctttag gatatacatc cacagatgtc actgcttggt tcttgacgaa aaacctcttt
     6121 tcgattgcac gaggagctgg tggcattgat cgaataagtg tgccagtaga cggttcgtgg
     6181 aattatgggc aaagtgatta tgctggcagt attcttgaaa ttgataatca aatgaatcaa
     6241 tctgctatta cagatttttt gaataaatga tcataaaaaa gatcaagaag aagctgcgca
     6301 aggcttttgt catgaatcaa tcaaacgatt cactcgtaaa aaacgctttc ttatggtaga
     6361 tttaaccaag agaggagctg tttacattgg atatctatct gaacttcaaa aatgagtcgc
     6421 gtgaagccat cgctttttat gaaaaagttt ttcagactga agcatcaggt atcaccacat
     6481 acggtgaaat gcctggaata gaacaaatga acttgccaga agaagcaaaa aatctaatca
     6541 cgaatgcacg gctgaacatt tatgatacat tagttatgtt tgcagatacg ccagaaggaa
     6601 ttggtcctga attagttgtg ggaaataatg tttctttagt catccagaca agaaatgaag
     6661 aagaaacgaa gcgcctattt gaaagcttag ctgagggtgg taagattgag atgccactgg
     6721 atgctgttcc gtgggctcag ttgtatggga tggtaactga tcgatttggc atcaactggc
     6781 agattaacca agagtgacag ctaaagatga atattttctg gaaacatcaa gcagcaaacg
     6841 gatcatcgtt tgtttgcttg atgtttttgt gtctatttcg actatacggt atcttttttt
     6901 tattgccaga tgcgaaaata tgttccataa tagagaagtc cgcaaaaaat taagtaacgg
     6961 aggtcagaag atgaagacgg tgatactagc tgaaaaacct tcacaagcaa aagcctatgc
     7021 cgaaaccttc caacagcaaa agcggcatga agggtattat gaaatcagcg atccattgtt
     7081 tgctggtgaa gtaaccatca cttatggttt tggacatttg gtagatatgg ttgctccagg
     7141 agcttatgaa gagcgttggg caaaatggtc tttagaaaat ttgcctattt tcccagaaac
     7201 cttccgttac gaagttccaa tggacaaacg tgcacaattt tcgatcgtaa aacgagaatt
     7261 gcagtcagcc gataccatca ttattgcaac agatggtgat cgagaaggtg aagccatcgc
     7321 gtggtcgatt attcgacaag caaacgcatt ttctaaggaa aagaactatt tacgtttatg
     7381 gatcaattct cttgaaaaag aagcaatcta tgaaggtttt aagaatctcc aacctggaaa
     7441 gaactatttt ccaaaatata aagaagcgca agcaaggcag aacgctgatt ggctgattgg
     7501 aatgaatgga agtccattat atagcttgct acttcaacga aaagggattg atggcagttt
     7561 ttctcttggt cgtgtacaaa caccgacact ctatatgatt tatcagctgc aagaagaaat
     7621 caaacacttc aaaaaagaaa cgtactttga aggagaaggt ttaattacga caaacaaagg
     7681 gcagttttct ggaaaaatcg taccaaaaaa agcatttaaa acccaagaag agttaacgaa
     7741 ggaaatagaa aaacttggag cgcatttagg taagcaaaac ggacggattc ttgaagttac
     7801 gaaaaaggaa aagaggttgc atagtccacg tttattttcg ctatctagtt tgcagacaaa
     7861 gatgaatcag ctaatgaaag caagtgccaa agctacactt gatgctgctc aaggattgta
     7921 cgaaagcaag tttctaagct atccaagaac ggattccttt tacattacag aaaatgagca
     7981 tcagtatctg gttaaacatc tgcaaaatta taaaaaattt ttaggaatag aagaagtaca
     8041 gacaactgag atcaaagcaa agaaacgata tgtcgatgcg aaaaaagttc aagaacatca
     8101 tgcaattatt ccgacaaaga cgattccgac tcctgcacgc tttgcgaagc tttccaaatt
     8161 acagcaagca atctatttgc aagttttgcg cactactgtg gctatgtttg ctgcagatta
     8221 tatctacgaa gagacgaccg taatgacggg cgtacagcaa ttaaagctaa aaagcatcgg
     8281 aaagatccca ttacagcaag gttggcagga aatcttacgc atcaagtcaa aaaagaaaga
     8341 agctcagact cttcctccta tcgtagaaaa tgaagaagca gaagtagaac tgaaaagtat
     8401 ggagaaagaa acacaacctc caaaacccta taccgaagga acgttgatca cagcaatgaa
     8461 aactgcggga aaaacgctgg ataatgatga agcgcaagaa attctcaaag aagtagaagg
     8521 aatagggaca gaagctacac gagccaatat cattgaaaat cttaagcaga agcattacat
     8581 cgaagtcaat aaaaacgaaa taactgttac gccaaaagga atcactcttt gtaaggcagt
     8641 agccaatgaa ccattactga cgagcgcaga aatgactgcg cgctgggaag ggtacttgag
     8701 aaaaattggt aaacaagagg ggacaccatc tgttttttta gagaatatca aaaaattcat
     8761 cctacattta ttggcagaag ttcctaatca aatcgacaag gtagactttt cagatgagat
     8821 tagcgggaca cgtcagataa aagcgatgga gaagaaaaac gatcaattag gaagatgtcc
     8881 aaaatgtaaa aagggaatag tcatgcttta tcctaaaatc gctacatgct tgaatccgga
     8941 atgcgacttc aaattgtggc caacagtagc taaaaagaag ctgactaaaa cgaatctcag
     9001 agatttgctt tcaaaaggaa agacaagtaa agttgtcaaa ggttttactg gtaaaaaagg
     9061 gaaattcgat gcagttttag tattaaaaga agatatgaca atcggttttt cttttccatg
     9121 gatcgaaaac agtggaacaa aagcagttga tggaaacaaa gaaacatcaa gaaaaaataa
     9181 tgaaaacgaa gtagagtaaa tgaaaacaat gaaatagcgg aatatttatt ccgaaaagtg
     9241 agaatataaa taccaataaa actaaaaaat atcagtgaat caagcaaaaa cgttggggta
     9301 ggctgatttt atatagatag caaggagttt ttttatttga aaaaagtgca ttcattttta
     9361 aattatctta tgggagcaat cacgattgtg gctgtgtacc aagcatttct aaagtatcct
     9421 gattacggga cgaagttgtt gtcattgacg cacaatcaaa cagcatattc accaacgttg
     9481 attttatcga ctttgactgc aggagctaaa agcgctactt atttttttca taaaacgaca
     9541 agcatgctaa agcgaaagaa acagcgaaaa caattgttgg tggtggtagc ggctatgatc
     9601 attatttatt ttctaccagt tattacacaa gtatttcatc aatattttgg ttaagaatac
     9661 gagagtttgt gacaaaagtc atgtcacaaa cttttttctt tgtcattttt tcgtaagaaa
     9721 aagcaaaata aaagtatata cattgattaa aagtatatac ttggatataa tgtacttact
     9781 atagaatgag aatggtatag agggtggcga aatatgaaaa aaatgaaaaa gtataaaatt
     9841 agaaaatctg gcaatagcga tgtaacaact atcccaccag aagtaaaaga attcatgggt
     9901 gtgcagacag gtgacgcaat cagttatgtt tttcaatctg atggttctgt acgaatgatc
     9961 aaagcacaag aagaacctga tattgattca ttagttgatt cgatcatgaa tcaatatgaa
    10021 gacgcgttaa aagatttggt tgatttatga ggtatctttc gactaaagaa attatcaaaa
    10081 tcaacgcgaa agttatttta cgtcactcgc caggcgaaat gatcggtgta aaagatgcaa
    10141 atgcattaga tatggccgtc aaacagcctt cacaagcagt attcaatcaa gaactctatc
    10201 ctgaaatcta tgaaaaagcg gcgattttag caattaattt agctaaaaaa catccttttc
    10261 ataatggcaa taaacgaact gctcttgttg ccatgttgtt gtttcttcaa ttgaataatt
    10321 gtccagttgc tttttctcgt caagaagctg ttgattttat cataatgatt accactagtt
    10381 cattggattt cgattcacta aagtccaaga taaccagtta tttacgacaa accgcaataa
    10441 aatgaacgaa ttaaaaactt tatttctcaa ttagatcagc atgtcattaa ggaatatgct
    10501 gattttttta tgtttaatca tacaaaatag ttttttcata aaaatatgga aaatatggat
    10561 taattttgaa ataattgatt taaaaggaat acaaaagagt gaatagtagg aaatagtggt
    10621 ttagaactag tgggctgatt ttttatatat tttagtttac ataatatata ttatacaaag
    10681 tagatttaaa aaatgataaa cctctctcga acggtttttt atcaaaaatc gtcatttttc
    10741 catcaaaatc tgcttatgca aaattataaa aaaattttgc agtttttctt actttttttg
    10801 tcgtttaatt gaatgataaa aaccagtttc tttattcagt taatcaaata tgaacgaatt
    10861 agatatgaat cattgtattt gccgttgcgg aaggattttt taattaacca cagataaaca
    10921 ttgataacga ttcgcttatt gtaatcaaca gattaaattt catatgttca tatgtacgga
    10981 tacattttcg gaccgattaa ttttaaccat tctgtttatt tgcttaccta ttagatatca
    11041 ataaaaaact gcttaacagc tatttcagct gttaagcagt tttaggattt ttagttcata
    11101 ttcattgttt cttataatac agtgttcaat acttctctta aagcacttgt tgatttgctg
    11161 aacattgctt tttcttcttc gttgattgat aattcaacaa cttcacgaac accattttcg
    11221 tcaacgattg atggcacacc tgtaaagata tctttttcgt cgtattcacc agttaaataa
    11281 gcagatacag gcaatacagc ttgttcgtta ttcaagatag cttttacgat acgtgcagta
    11341 ctcataccaa taccatagta agttgctttt ttacgatcaa tgatctcata agcagcatta
    11401 cggactttat cagcaatcac atctaattca tcttgggcaa tacgatggtc tttttctaca
    11461 atttcaaaca ctggtttacc accgacagtt gtatgtgacc atgcagcaac ttctgaatca
    11521 ccatgttcac ctaagatata gccgtggacg ctgcgtgggt caacttttaa tttcaatgcg
    11581 atttctttac ggaaacgagt tgtatccaat gttgttccag taccgataac acgtgatgtt
    11641 ggcagaccag attcgttcca agcgatatat gtcaaaatat ctactgggtt tgaagcaaca
    11701 acgataatac cgtcgaatcc tgatcccatg atttctttta cgatttggcg catgattgac
    11761 gcatttgttt taactaaatc taaacgagat tgaccaggtt tttggttgat accagctgtg
    11821 ataacaacga tatcagcatc tttacattct tcatagccac ctgaccatac agccacattt
    11881 tcatcgcccc aagccatacc atctaaaagg tccaatgctt ccccttctgc tttttcttga
    11941 ttcacatcga tcaatactaa ttcattagag attccttggt tgatcattgc ataagcgata
    12001 cttgttccaa caaaacctgt accgacgatt actactttac gacttgtttt tttcatgaat
    12061 aaacagctcc ttttcataac tatttgttac tttcatgaaa agtatagtct tgtttattca
    12121 ttttatcaac atgttaatta taatagttgt tattataatt tttgatggaa acgaattcct
    12181 gaatacgcat aacagataaa tgacaaatgt ttacacctat atcccctgat aatacaacca
    12241 aaagtttaga actgaaaata aatccaaaaa aattcgctgc aacgatataa taagacagca
    12301 atcgcaccta aaacaatttt ccttcatatg ctttagtgaa agattttctt cttaatgttt
    12361 atttctccat tcattgggag tacatgttga atacttcttg aataatttga ataaagaagt
    12421 cgtttgttta tatccgatac gattagcgat ttcttccaac gaaaaactcg tttcttgaat
    12481 cagttccaac gcaaagtcga attttttctt tagaaccagt tcttgaaagg aagcatcaaa
    12541 atacattttc aatttattac taagatagac cggattgtag ccaaaatgag ctgctgtttc
    12601 ttttaacgta caagaagtaa aatgcttatc gatataatct aatactctaa gcatctcatt
    12661 ttctgcgcat ccatctgctg atgaaaagct ttgttgttct aataaatgag tcaattcgat
    12721 cagtaatagt gatgtataga gatttaacga acggatctta tgactgtatg tatcaaaata
    12781 aatcaacagc atattttcaa tcaaatgcgt caaacgactt gtttttccgc cgcgaaaatg
    12841 aatgaattgt gtatgttccc ctttttcttt tgatgcattt atcaaaaaag aagaaagtag
    12901 attatttgtg cttgccaaat gattcaatat ctctgtagat aaggtttctt cttttaataa
    12961 gatgttgatt aaaatatcct cttgccctgt gtattcgatt ctttgagtag cttctttatc
    13021 aatgatcacc acgtcacttt cttccatctc tatcctttct ccattaataa tttgtaaaca
    13081 tgtaccgcta tacatataat tgatttcaac aaaatcatgt gtatgctcgg gaacttccgc
    13141 atatcgacgg tgtttactga tatgaatatt tccctgttga aatagatccc ctcggtggat
    13201 ttttggcggt gtctgaagat ggtaagctaa gtttaaatca ttgatattca ttccttgttc
    13261 acgctgcaga gtttcgattg attcttcgtt acgcaaaaaa aatgtctaat tcagctagtt
    13321 ccaattgact ccctcctttt tgtaagcggt ttctttcgct tattagttca cgctgtactg
    13381 ctattatatg caaagctatt tttggtttca taaagacttt ctatggttgg gacatgaact
    13441 tcctgtgatt ccgctattga gagaataacc acttcatact atatttttga taagcgctta
    13501 caaaaatgaa aggaacatgc ttatgaataa aaagatgatg aaattttctc tgctgtcagt
    13561 ctctcttatt ttgacttctg ctggtgcagt cacgtctgca attcccagta tgtcagctac
    13621 ttatgccacg cgttctttat ctgctgttga attattaacg actgctccct cttttatggt
    13681 cactattttt gttttgatta gtagttttat tgctaggaaa atcggacaaa aacaaactgt
    13741 gatcatcgga ttagtgattg catcgattta tggtatcctc cccctcttct cacaaagtta
    13801 cagtattgtc ttagcttcaa gagctggact aggtattggc tttggattga tcaattcttt
    13861 ggcagtcagc atgattgctg ccttttatca cggagatgaa cgagcctcta tgattggttt
    13921 tcaaagtgca tttcaaggat ttggtgcagc tttaatgaca tttgttgcag gacagctagt
    13981 acagttcggt tggcaatata cctttttagt ctacgccatc agcttaccta ttcttgtctt
    14041 gtttgttttg tttgttccta cacctgaaac aactgaactt caatcacatg gcacagcccc
    14101 aacaagacaa gtaatcaaaa cgaatcctaa aatgattagt tatggtattt ttctcttgct
    14161 ggtcatcgtg gtatataatg ctgtatcgat taaattagcc acagtcctga cgacttattc
    14221 tctaggaaac gaaactaatg cagcgaatat cttaacaatc atgcaattgg caagtatggc
    14281 tgccggagtt tgttttggct ggcttcagac aaaagcacat cgctatatgc ttacactttc
    14341 tttactactg atgggaatcg gctttgtatt gattgccact gtgataaacc tgtatgtgat
    14401 tgggtttggt gcgatcctaa caggaatttc tttttcgtta ttcattcctt acttattcaa
    14461 ccaagtaagt atccaagcgc ccaagtacgc ggagagtttc aatacttcaa tcttattggt
    14521 tggcgctaat ttaggtactt tcattgcacc atatggtttg ctctttctct cttttgcttc
    14581 tcttgggagt aaaacacttg ctgttttcgt caatggcagt atcttgctgt tgattagcgc
    14641 gcttattagc cttctagtag tacacaggac gaatagaaag acagtgataa gagtagatga
    14701 agaaataaaa gaacaattga caacaaaata aatttgatgg aggtcgtgta aaatgacaaa
    14761 tgaaaaacat aaagatagat ggctttggta tcctggagac tttgagatcc gccatggact
    14821 gctacaaaat ttccaacggg aagaacgagg ttttgactgg ccagcgtact ggtacatgga
    14881 tgattgccat cggaacgtca agtttaagag atattacttt cttgatcaac cttccatgtt
    14941 taaagtgacg atccaaggag ttgggtatgt agaaattaat ggacaaaaac atccatgtgg
    15001 aaaatggctg acttgtccag ctggtaaagc aaaaattcgt atctttgtag gacatacatc
    15061 agggctacca gcgatgttta tcgagggaga cgaagtaaaa tcagatattg gctggacagc
    15121 aagtaatttt attgaagaat atccagctgg ctggagtccg ctttatgtcg atatcgcaaa
    15181 agatccaaat caaatctatt atcaaaaaga atgcgtccat ccagtcactg aaacggagat
    15241 tggcggagga atcttattcg attttgggcg agcagtgaat ggctgtgtag aactaatatc
    15301 tctggatgac catatcgaat ctatcactct atgttatgga gagtccgatg tagaagctat
    15361 ggatatcgat tattgctact ataagcaaat aggaatgaca agaaaaatga aagctcgtaa
    15421 acgcgctttt cgctatttgt ttataccaga ggtttctact ggaatggttc aacttcaagt
    15481 ttttcatgaa tttttatctc tttcgaaaca agctgctttt tcaagcgatt cttctttact
    15541 gaatcagatc tggtcagtat cagaagaaac cttcaagtta tgtagtgatt tgttttttat
    15601 cgacggtatc aaacgagatc gctggatttg gtctggagat gcgtatcaat cattcatgat
    15661 caatcaatat cttttttttg acgaggaaat caataaacga acgatattag cattaagagg
    15721 acaaaatgaa atcaagcagc atatgaatac tatcgttgac tattcgatct tgtggttgat
    15781 tggtatcgaa aaccactata tgatgacgaa agactatgaa tttttacgca tcgtctaccc
    15841 taagatgcaa tcattaatga gatacttgat ggagcaaacg aatgaattag ggtttattta
    15901 tgggagagca aaagattgga tatttattga ttggtctgaa atggataaag aaggaacgct
    15961 tgctgcagaa caagtcttat tactgaaagc ctatcattcc atgatcactt gcggagatat
    16021 cttagctgaa acatatggag agaacgaaaa ttatcatact catctctatc aagaaaaata
    16081 tcaactattg aaacaaaacc tatttgacta cttttgggat gaagaacttg gcgcttttat
    16141 cgattgctat gaatctggga gaagaaatgt gacgcgtcat gcgaatattt tcgctgtttt
    16201 attcgatttt gctaacaaag accaacagca atcgatctta aagaatgtct tattgaatga
    16261 cactatcaca cagattacta ctccatattt caaattctat gaacaagatg ctttatgcaa
    16321 actcggacag acgaatatcg tctaccaaac gattcttgat tattggggag ggatgttatc
    16381 tcatgatgcg gtaactttct gggaagaata cgaccctact caaacaggaa atgaaaagta
    16441 cagtatgtat ggagatcctt atggaaaaag cttatgccat gcatggggag caagcccaat
    16501 ctatctttta ggacgctatt ttatcggttt gtatccaaca aagccaggtt atgaagaatt
    16561 tatgatacaa cctaatctag attcatttga aacactgaat tgtacgctac ctatcaaaga
    16621 tggaaagatt tcgcttgaaa aaacaaaaga taagatcgtg attacttctg atagaacagg
    16681 cggaacagtg aaaatgaatg gtaaaagtta tcctcttcta gcaaaacagc cacttgtctt
    16741 aacaagctat tcaaaaataa atgcataaaa caaaaaactg cttgcgacat atcagaagac
    16801 tttaaatctt cttctgatat tgtccaagca atttttattt tgaagtttgc ttaattctgt
    16861 tctttagaaa caatgtttgt tctttttccg gcaaaaagaa agctagataa tacgacaagt
    16921 aaaaagaaag cgatgattcc aactgtcaag gctatttgac cgtattctcc tagtttccca
    16981 agtacaagtc ctggtactag ataatcagta tcggcaaatg tagaagaagc gattttaaga
    17041 tctcctaata ctggaaggat aaataatggc agccaactaa tcaataagct attgaaagca
    17101 gaacctaata ccgcccctct tctaccgcca gtcgagttgc cgaagacacc agaagcagct
    17161 ccgcagaaga aatgtcctac taccccagga atgataactg tagtttgcaa gcctatcata
    17221 gcaaacatgg atagtgttcc tacaaagaag ctaacaaaaa agccaattaa tacagcatta
    17281 ggtgcatatg gaaaaacgat aggaacatct aatgctggtt tagaatcggg tacgagtttt
    17341 ttagcaatcc cttggaatgc tggaacgatt tctgccaaca ccattcgaac cccttgaagg
    17401 acgataacaa acccagctgt gaatgttcca gcttggatca gtgcaaagat tacagcgttg
    17461 tctccattgc ttagttctct ttcaacaaat ccaggaccag ctaacaaagc aagtgcgaca
    17521 tatacgatcg acatcaagag catgatcgat acagtagaat ctcgcaaaaa gctgaaactt
    17581 ttaggaatct ttatgtcctc tgtagaacgg tctttgtttc caaaaaactt tccgatccat
    17641 ccactagaag cataaccgat atttccggta tgccctaacg caacttgatt gtttccagtg
    17701 atgttcttca taaacggttg acaaagagca ggcgtaatag ttaatagtgt tccttcgaag
    17761 accccgccta ataagatcat ccacaaattt gcagtaaacc ccgcgcttac taaaatgact
    17821 gctgttagac aagaaacata aagcattgct tgacctgtaa gaaaaatgaa tttatatctt
    17881 gtgaatctag caagtaaaat attcacgatc atccctacta gcatgatcaa agcagtaggt
    17941 gtaccgtatt gttgcaaagc aatcgccact actgcttcat tgctaggaac tactccttga
    18001 gtatgcagag ctgtttggaa catcgaagca aaaggggtta gtgaattact gattaaacca
    18061 gcaccgccga tcagtactag gaatccgaca aatgttttga tagttccttg gatcacttct
    18121 gaaaatttct tcttctgaag aacgagacca agcagtgcaa tcaaagaaac gaggatggag
    18181 ggctgactga cgattgacac aaacaaattc aacaatttat ccattgatag ttcctccctt
    18241 gaatcatttt tattcttttg acaagatctt cgttactttt tcttttactt cttcgctgtc
    18301 aatgatcgat tgcaaaggta cgagcttttc atcaggtata gaagttagcg tatctttcaa
    18361 agaatgctca atgaagaaat aatcagccat atcgctagat acacttccaa catccgtatg
    18421 acttacttca aactcgtcca catctgctcc aagatctgca agtgcttgtt tgatgttcat
    18481 ctctaccata aaacttgttc ctaatccact ttgacatact gcaaaaattt tcatatcatt
    18541 cgtctccttt tcttatgatc gctaatattt cttcttttgt tgatgcgtgt aataaatctt
    18601 gaagattttg tttattagaa agtagctttg ttaaatttgc caaagcccga agatgtgcct
    18661 cattatcgat agcagctaaa cagatgaaca aactaatggg atgggctgga ttatcaagca
    18721 gatccacagg ttgttgaagt ttcagcaaag acatccctac ttcgtttacg ccatcttctg
    18781 gacgagcatg aggtaatgcg atgtgatcgc caatatggat aaacgcacca tactgctcca
    18841 cgcgctcgat catagctttg atataacttt cttctatttt attttctgat aatagcggct
    18901 gtgcggcaaa tgtgattgct tcttgccagt tttttggttg atccgataat tggatcattt
    18961 cttctgttaa taattcagat agcataggac gttgatcctc cttcttttct aaaagtttgt
    19021 tcattttacg atttaatact tgatagagct tttcttcgtc tacgccttct tttaattcga
    19081 tataaggcag tagcgccgac aacaattctt gggcagaagg cattgaaaat cctggtatca
    19141 gccaatctct ttgtacttga ttgatcagct gatttttttc caagtcagtc atgattggat
    19201 gcagaacata gagagacttt ttcttatcag taagtgtgag aggtacagta gaaaaaataa
    19261 tatcgtaaga agtttcgtca acctcgtgta agcggtcagc tgaattagtc tctgtaaaaa
    19321 agatcatcgg gaataattgc tgaagttcac tttttaagat caatgaagag ctaatgccac
    19381 ttggacagac gatcacggct cttatttttc tatttctttc ttctgcgtcc gcttttctga
    19441 tctctccgcc aaatagtata gtgaaaaaac caatctcttc ttcagggatg ctcttcccta
    19501 ttcgtctttc taacggaagt aatgcttttc ttgtcatttc gtagatggaa gcatattgat
    19561 gcttaatttg atcgatcatc acattaggta aataaaaaga ataggaaata cgaaaatagg
    19621 cagggaccaa gtgataaaag acattcatca ataattcacg aaacgaagca aattctacgg
    19681 ccatcaggaa ttccatgcga tggatgactt ctgaagaaca ttccagcaaa aaatcaagtg
    19741 caggctcctg gacatctcct tcaacgatcg atgctaagca aagagagaaa aatataatct
    19801 ccgaattttg atgttcggaa tagccaaggc cagtcaatac ttgtcgacta atgtcagtga
    19861 ctgcaagaga agccaacagt tcagcatctt ttaccagttc catggatgtt tttccaattc
    19921 gaatggttgt caaactcaaa taataagcta attcatccat tcgatttggt gcgaatcgaa
    19981 gatctgatag tgaaatcgtt ttatctagca aatctctaac tttggcgtaa taatcaatgg
    20041 aaagggttgc ggttaaatac gtgagcccaa atcttccagc aagtgactgc atcaaacgag
    20101 cagtgcgatt ttttgcttct cttcttaata ttgcttctga ccctagcagc ctaaaaccag
    20161 ttttcctagt atacgacagc tgacaatctt ccacttctaa ttcatttctt atctttttga
    20221 tatctgacag gactgtccct ttagaaacct gaagaaaatc ttgaaaatga aaaacagaaa
    20281 cagacgttgc agtcgaataa accatcaaat aaagaagatc tcttcgctct tgttcggtat
    20341 acacagcttc aaatcgagta atatccaaaa atttttctgc ccagtcgatt gctcggaatt
    20401 tctttatacg gatacgggta tcatccacat attcggcaaa aggagttaat tgtttgatcg
    20461 cctcgcttgt atttacttcg atgatctctg ctgctttttc tagactgatt tctcttggtg
    20521 ttttcaggag ataactaatt ttgtagttca cagcgctgtt cacctcctac ttatattcta
    20581 gtatggtagc gcttttaaat cgaggggtgt ttggtacaac ttacagttgg atttttttta
    20641 cgactgtacc gaacgatttc tatcgaatgg atacagaaaa aaagcaggtg accaaatgtc
    20701 tcctgctttt atgaattgat ttcgtccgat caatgatgat catgtttatt ttttgaggtc
    20761 agttcttcaa atttttcttt gacatcttca accgcttttt cgatatcttt ttcaaagtga
    20821 ttgggctcat taggctttgt ttcctcttct acagaatttg aaccagataa agctgtttct
    20881 ttattttctg tttcaccaga gtttgtgcca gctaatgatt cttctttgtc ttctgtttca
    20941 ccagaattag ttcctgctaa agccacttct tcttctgttt taggggccat tgaacctctt
    21001 aatcgtttgt gtttttcacc gtcataattt gtcatgttgg ttcctcctag tagttctata
    21061 ctttttcatc gtacaataag acagtttatg cgtcaaaaaa caaacccgat tcttacaaat
    21121 atgtcatatt tttccttctg attcttgaat gcttttgatt ccttcttcca aaattttcat
    21181 ttgtaagatt gtttcttcat ctttgatgac tttttctgcg ccattaacta atgtctcgta
    21241 aatcccttcg tagacacggc tgtaatcacc aacctcggaa attacttttt cttcatgata
    21301 actcccttgt tcatctatat aggtcaatac accataatgt tcgggcaaat cgataccaaa
    21361 gtcttcatga tcaggcatgt aaaacatttt cagatgttct tcttgtcgat cttttgtttg
    21421 tttcacgaac atcccttttt ttccgtaaac gacgaaactt ggacgttctt tgatgcggaa
    21481 ataactggat tttatcgaaa ttttcatatt tccatagaaa aaatccagat cgaagtaatc
    21541 attcattcgt cctttcccta aaagttgacg tacatcatag ctgatatcat ctggttcgcc
    21601 gaaataagaa agaacttgat ctactgtatg acaagcatgt ccatataaat agctgttcgc
    21661 agtagaaaat tcatgcgtat tttctggtac ttccggtctg aaataatcat aatgcatttc
    21721 tacttctaaa atatccccta attttccgct ttcgattact ttttggactg tcaagaagtc
    21781 agaatcgaac cgtctgtttt ggtaacattg gataaataga cctttttctt ttgctaatgc
    21841 aaataactct tctgcttcct ttgacgtttc tgcaaaaggt ttctctacta gtacattctt
    21901 accatgttcg agtgccattt ttccatattc ataatgaaat tgactaggtg tagtgatgac
    21961 aactaattgg atctcaggat catcccaaag atcagacagc tgatcagtat attcgatgtc
    22021 ttcgaatgtt ttccacactg gttcagatgg ggaaaaaatt tttttgatat tgattttgtt
    22081 cgtaagtttt cttgaaaaag gcaaatgata gcgatttgta ctctttccat tgccaagata
    22141 agcgattgta agcatgagtg gtgcctcctt ttattgatgt tttcagtata tcctagaaaa
    22201 gcgcagaaag tatttataat agctattctg gtaaaaaagt tcagaaaaac acttgttatc
    22261 attcggtttg gtgaaattaa tgttcaaagt aaggataaaa atcaaaaaga tagtagcgga
    22321 accaagtgtt tatcagtaag atagaatttg gaggtcagat catgcttatt gaagaaaaac
    22381 taacaaaaca agagttgttt accacgacag agaaacggat tgtcgattac atccgtagga
    22441 atatcgaagc tgcagtctac atgacgattg aagaattagc aaaagctacg tatacttccc
    22501 attcagctat cattcgttta tgcaaaaaaa tgggattcag cggatttaaa gaattccgtt
    22561 tcgagctggg gcgggaagtt catcaattga ttgctcagtt caatcaaacg attgatccta
    22621 attttccttt ttcaagtgaa gatagcactc agcaaattgc aaagaaaatg gcggatttat
    22681 cgatccagtc aataaaaaaa gcacaattgc agattgaaca tgaagattta gatcaaatcg
    22741 gtaaagtatt gaacaaggca cagcgaatct ttctttttgc aaaaggtgat tctcaaatca
    22801 cggcaaggaa attccagaat aaaatggtca agttgaataa gtttttgatc atggctgaag
    22861 aatacagtga ttcttcttgg aatgcagcca atttgactag cgaggattgc gccattttta
    22921 ttagctacag cggtcgcatc catcattatg aacgaataat gacctatttg aagcatgtag
    22981 aggcccctac cttgctgatt accggaaatc agcattcaga aatggccaaa caggctgata
    23041 tgtgtcttgt tatatcgcag gaggaatatg attttgctaa agtagcgact ttctcctctc
    23101 aaattgcctt cgattacgta ttaaatacgt tattctcagt gatatattct caaaattttg
    23161 aagagaatat ccgcaacttg aaaaacaaac aagaattgat gcaaaaaggc cttcttaaag
    23221 aatatcggaa aacttaagaa aagatcctca tttagtaata agaaagatag tgtttgatag
    23281 gctctctttg atatcatcat aaaaacaggc tgaagttttc tttttcaaac ctcagcctgt
    23341 ttgtttacgg aacgattcga atagatatat tatagaaatg aggaatagct aacttctgtt
    23401 tcttattttg aacgattgac gaaaaagata tataagaagg aggaaaatca gtatacatgc
    23461 agctaacaat ccatacagga aaaatcgttt gttctcggat actttctgta cttctttttg
    23521 aacttctttt gcatgataag gaacccggtg ccctctgaca agtaagcgat gactgttgac
    23581 catataaggt gtacaagtta ggagtgtcac gaaatcctgc cctttttcga ttctcagatc
    23641 ttttgtatca gtcggttcta ccgtcttgat ctgatcgact tgataagcga gtgtccgtcc
    23701 attgatttcg atatagaaag aatcacctaa agtcagtttc ggtaagtctg tgaacaactt
    23761 tgcttgaggc agtcctcgat ggctggaaat aacggcatgt gtattttctc cccccgtagg
    23821 ataagacgtt ccttccaata atgaggcacc tttttctagc agcacagtat tcgtttcatc
    23881 aaaaattggc aaatggacat tgatctcagg gatcgtcaaa ataccgatcg tatgtttctc
    23941 aaaataggtt ctatcctttt tcgcaggttc ttttttctta gtaaagggat ctgcacctgg
    24001 atttccacct tcttttgcta attgctggtt tttctttgtc atgttttctt ggattttagc
    24061 catgacttct tcattttctt tgaccgcttg ttgctgataa tgagagatga tctgctgatc
    24121 cagataatta ttcagcgcgt cgctaacaaa tggataagct agtatcccta ttcctgagag
    24181 aagcaagaaa agcatcagca gatctagaag tttccttttc tttggtttca ttcgtgttct
    24241 ccttgtgatg actgtttgat aataaaagaa aaaggagcat ttgcgtaatc cgctgctcct
    24301 ttttccaatt cttgcaaaaa gactaaatct gactgtgctt gcgtctagca aagtacagtc
    24361 cagcaatcag tagaaggact actcctgcac cgatatacac atagattccc ttaccgcctg
    24421 ttgaaggaag tgtacctttg tgtttatttg gtattttttc aggagaaatc aactgtcctg
    24481 ctgttacata agattgttca tcgatagtaa atgctacacg gtttgttaat ggaacatatt
    24541 tttctggcgc tttcgtttct tccagatagt acgtgccata ttttagacct gtcacatcga
    24601 ttaaaccgtt acttgtggtt gtaaaaaccg ttgctgattc tttcgccgat acccagctga
    24661 cggcttttgt ggatgggtcg atcgataaat atttcgctgt gtcactatct tgatcacgaa
    24721 cgacgaattc tgctccagca agtgtttgat ctgatgtaac gtcaccatct actttaacaa
    24781 atcgtttgcc cccagtaacg acatcgactg acggtggtgt ttgatcattt gtatgcccgt
    24841 tatcgacatt tgcttggtta gaaaatcctt tggttggatc tgctttttcg ttcaaatgca
    24901 tatagtaaac aaatttcagc gtaccaccag gagtgagtga aggaatataa ttcgagtcaa
    24961 ctgaaaccgt gaatccgttt gtttgttcag tgacagaata atttgttgga tcgatttctt
    25021 tatccccatc atacaagaca tacgcatacg ttcctgaagt ttcatgatca aatgtcaaag
    25081 cggcgtcatg agtatcaatg agtttgaatg tcgtgtactt gttttgtgtt ccttctttat
    25141 cagcgatacc taaaggaata ttgacagaga tctcatattg gattttttct ccgattgcga
    25201 catcttttcc attcaattga ggtgttgttt tatcaacttt ggacgtatca tttttgattg
    25261 tcttttctac aggagtttga ctatttgcca agatctcaaa cggcgtgttt gtttgattat
    25321 caatcatttc cgcattatca ggagctttta cttcttctaa attatatttt ccaacctcta
    25381 aatgattgac gatcaactga cctttttcaa tcgttgcctc ggcaaagtca ttgttgccga
    25441 tgtcataaga atgaccagta atgaaatgtt tggctttggt ttgatccgtt gtccaagtgt
    25501 acaatccatc tgtgacactt tggatgtatt ttttgacgct tggtcttcct tcttctttag
    25561 aaataataaa ttctgctcca tttagtgctt cgttttcggc agtaccgatt tttgtaactt
    25621 tcaacgttcc atcattaccg actgtatttt tagggtagag atggatagta tctagttctt
    25681 ctgtcccgta tttataagag ccatctgctt gtttgatcat ctcatataca gggaaagcta
    25741 aaaccatgtt tgcggcagct gacactccgt cttttggttc ttctttgatc gtgtagactg
    25801 catctttccc attttgtttt ttaggtaaag ataaagtgac atttccatca gcatctgtcg
    25861 ttcctgaagc aactggtgta ccaggagtca aagactggac tgcttgtttt gctgcatcca
    25921 cggacgctcc tttatctcgt tgcgcataaa attcttgagt gacgttataa actgaaaatg
    25981 aaatatcggc taatccttgg tattgatcga attcgctcat ttctttcccg ctgttttgga
    26041 ttaaaggatc gggtaaatca gtcattttct ttttatgaag gatgacttga gctgctgtct
    26101 cctctgcaaa cacttttttt gcgccgaagc tgtttgtgag taatggtaaa ataaggaaaa
    26161 ggactcctaa cataacgttt atttttttat gatttttcat tttttcactc ctgttctttt
    26221 tttgataaac aaccagattg caaagcttgc gaataccata ccaacaacgc ctaaaagtgt
    26281 atttttcgtt tcgtttgttt ttggaagaaa tggacggcta ttttcttttt tattgactac
    26341 tttcaatata ctgtccgcct ctttatcctc agaaagaaaa gttgaaatgg taaacggaat
    26401 ttctgtttca cttaaaatat aaccagaagg tgcttcgatc tcttttaatc gataacttcc
    26461 tgttttcaac ccggaaattg aaaaagcgcc atttttatcg gaaatcaggt gaagcgcatc
    26521 tgattcgttc tttgtccact tgtatccgtt ggctgtttgc tggaggtaat ttcctgcttt
    26581 gtttttaata aggaatactg cgccagctaa tcgtttatct ggtttatttg tctcgatttt
    26641 gacaaattgc ttactccctg tatatacaga gactttcttt gtactgatac caaaaccaaa
    26701 atccagtgtt ccgttgttgt tgatttcctt gttcgcctgt gctgtactgc ttagctgcat
    26761 ctgataagaa atggtcagtt tttttccagc atatttttcc aacgaaggga tcgaaaataa
    26821 aacatcaaat ccgtgaggtt ttttgtgtat gacaaagcct tctgtcagct tttctccatt
    26881 cgatgaaatc gttaaactat taggtaaaaa cgttaatgct tcatccgcac tatctgacaa
    26941 ttcgaacttt tgatagtcaa ggatatttac aggaattgtc gtatgcaagg aataagtgat
    27001 tttttcacca atcgtaaaat catttctagg ctcttctaat accttctcaa aaggtggatc
    27061 agggtagtcg ttttcttcat ttttaggata caaatggata gttgaaagtt tttgattgtt
    27121 ttgtccatgt acaggaagaa caactaccat attctctgcc ttttctttga cgacttctgg
    27181 tgctttggat tcaatgaaaa gatacgcttt atctcttttt tcttgatctt tagcggccag
    27241 agaaaaagaa gcgataccat cttcgttgtt aagagttgta gttgttgctt ctgcggtaaa
    27301 cgtaccggaa gacgcaccgt tttttgcgat ctctgtttgt gcttcttcta ccgttttgcc
    27361 cttttcccgt agatggtaaa aagaatctgt gacatcataa acttggaatg tgacaccatt
    27421 taatcctcga tacgtttgta ataacgcttt ttcttgtccg tcatttggat gatttttcgg
    27481 cagttgcccg tttgggaaaa gcaatttgtg taaagtaatc tgaaccattt ctgtttctgt
    27541 ttctgttgct gcctgagtaa aagctggttt aaatagtaac aagaagagac acatactaag
    27601 ccaaccaagt tttttcatat ttagctgccc cctctttctt ttttcaaaaa aagataccaa
    27661 atagaaaacg cacaaccaat catccctact agatagattc ctaaacggcc aattcctccc
    27721 gtttcaggta atggtacttt tgcctgattc gtgatgtcta aagaaatctg gttgtttttg
    27781 gctcctggtg acagaacaga ttcatgatct tgtccatcca cttgaattga cccatcttcg
    27841 tgtataacta tagtaactgg ctcttttaga ccttggtatc cttctggtgt aaaagtttcg
    27901 gtcagcgtat aagttccagg ttttaaattt tcgaatagaa aggtatctgt ttcttgtcca
    27961 tcttttggcg attctaagtc catttctggt ccctgcagtc tgaattttgc tccttttaat
    28021 gtctgtccgt tgtcttcttt tttgtgtacc gttagatcaa acgcttttag tcgattttga
    28081 tgagtgagcg tccatacatt atttgtcatc tcggtatttt ttcccgtgta aatgattttt
    28141 ccatatttat cgatttggaa ttcataattt cccggcgaag tatcatatcc ggcaggacca
    28201 gctgtttcaa cgactcggta tttaccaggt gtgagtgaat caaaactggc aagacctttt
    28261 tcattcgttg tttggctgtc aattggctga taagtaccat ttgcttcttt tttctgtagg
    28321 gaaaatgctg ctcctttaag atttatctct ttgtccgtcc cttgcatcgc atacttacgt
    28381 actgctacag gaacttcaac aaaaggattt tcaatagtca actggatcgt atcatcggaa
    28441 gtagtgactg tttttccatc aatggttacc gtaccatcag aagcgatctt gatttcccaa
    28501 gtagtctttt tgcttaatcc atgcccttct ggagcttttg tttctgtcag cgtataggtc
    28561 atttcttttt gcaatttgac attttctgga agagaatagg ttccgtcgcc atgatctgtt
    28621 agtaaagtat caatagaatc tcctgttaat ttgaagacag caccgatgag attcttttca
    28681 cctgtagagg aatttttcgt tattttcaag tttaacggtg tgaattgttt agtatttttc
    28741 catgtcattg catctatttg ttgagaatcg tatcctggta caggtaattc tttgattgtt
    28801 tggtaactga atgcttgacc ttgattattg tattgaggta gtgataatat ctcttgataa
    28861 ctttctccgc tatttgcaga taatttgtca atgtctgcac gttcccacga atttgtagta
    28921 tctttagctg gtttaatgat tcgaatatat ccgtttttcc aagctgcagc atttgtcgta
    28981 tgttcccgtt gaatctcaaa agtaacttga tctggacgat cagctagatt gttgtcaaat
    29041 tcttcccata actttttgat gtgaagactg actccgggag ctttagcaga tggtataccg
    29101 aattcagcta attcattggt atcaatgttt ggctggaaag ttgtcctgcc gttcatttga
    29161 taccagaaat ttggatggaa gtcctcattt tctgtttgga ttctcacttg gtaatggatt
    29221 tggatttctt ggtcttttcc taaatagatc tgattgctct tgatggtatt tccttctatg
    29281 gaaatagatg gagtgaccgt tgtaggactt gtccccacac tcttgactga aagtgtacca
    29341 ggctgataaa tgaatggttc tgcgattgga tcatttattt gtccattgct tacagttgct
    29401 gagatctgta cagctttttt ggctaggtat tcagagatat ctgttgcatg atcagctgat
    29461 tcatagtaaa gatcgccttt ttcatctgat gaaaccattt gtcgcatacg agactctact
    29521 tctgcttttg agagaccagc tgccggatcg ctttgaagtt ggatgccaag accatgtatt
    29581 tcgattcctc gttctttgag tgccatcgct tctccgatgg ttgcgataaa cgtactgtcg
    29641 attcttctgg atagattgtt ttggtcaggt gcatcataga ttcttgagat tagagaagta
    29701 tttcccggcc gatcttgcgt attagaaaac tgagttccgt aataattgct gcttgattgt
    29761 gcgtgtaccc gctgtacttt ataggaaaat gttggtacac catccgtcag caaaacgatc
    29821 acttttttat gtccatttgg aacggatagc atgcttcctg catctcttag tgctttttgt
    29881 gtaaaagtac caccatttgt ccgtgaaggt gtaatggatt ttacttgatt tttcactgaa
    29941 tcaaatgaac ccatctgtac tgcaccgtta ctgtagctat atccttcgct tgagtagccg
    30001 acatatccca tattgatttt gtctgtgata ccgctatctg ctaaagtatc gacaaaacga
    30061 tcgacaccaa tctttacttc accgatccga ttattgtcgt tcatacttcc tgaccagtct
    30121 acgaccaata cgagatcaag aggcgtgata tctttttgta catttccacg agcattcaaa
    30181 taaacatcaa acaatccggg tgtacttgtt tcctttgcat actttcgtat cgcatagtct
    30241 gcttgattac cggttcctcc atattcgata tacgaatggg tccgatcatt aggatctcca
    30301 ttccaagaat ttataccatc ccattgattt gttccgtttt tattgccttg atgatcaaga
    30361 acatttgtat ttcctgtagg ttgccaactg gctttaggat aagtgccctg atcatctgtt
    30421 gtatattctg taggaatcgt ttgattagat ggcacactca cagctggcaa ggataatgta
    30481 ggcaatgtaa atgggctgac agaattttcg ttttcttttg atgattcttc ttctatttcg
    30541 tctggctttg gtactgacac atctgtatct ttcttatttt ctgtctcatc aataatgtca
    30601 tattctttat tatcgacgat cagcttgttt gcctggctgt ggtaaagtgc tggatcgatt
    30661 ggaaaactca gatcgatagt ttgtttagtg tttgatgaga tttccaacgt aattttcccg
    30721 ctatttacct gataagcata gccatctcct tcttttcttt ccacatcact taagtaattt
    30781 tcgactagac caatttcttt ttctatcttt tcagcactgg tgttattcgc atttagcttg
    30841 atgttcagtg ctttttttcc agactgatcc gaaatgactt cagctgaaat tgtttctaaa
    30901 actgttggat catctgtagt gtctgctatt gcagataatg gcacaaagtt tgataaactc
    30961 aatattatca gcatgaaaat aactttcagt ttcttccctg tggtcgtcat ttttcccctc
    31021 ctttttcttt ttttctgttt tgacgtgaat agtgaaaatt attaaaataa acaggcgtta
    31081 cataatttta tttattttaa tatgataatt attatacgaa gggcgctaaa gggaatcaca
    31141 ccaattttca taccaattgg tttcatttat gaagttgatt ccttcgatta atgagcgttt
    31201 cattgaaaga aaagggttga gggagaaaaa catatgatca ggttgttgga acgaaactat
    31261 agaaagatgg aaaaaatcat tcgaattctg tccatttctg acaagtggat gactaaaaaa
    31321 gaacttgcca aacgaattgg tagttcagaa tctacatttg taaggtatat cgaagagatc
    31381 aaaatccgct ggggaacgga tgtaacgatt caatcttcac aaaaattggg gtatcgtctt
    31441 gaacatttga atgtaccagc ttatttaaat gttctgatgg aaatgtcgca aagttctaca
    31501 aacagtcgtt tattaaatga gattattgtc aatccgggta aaacgattga gtattattgt
    31561 gaaaaaattt ccatcagccg gtcttctttt acacgtaagt tgaaacaatg caatcaaatt
    31621 ttagaaagct atttattaaa agtgatcgtt gaccaaggtt ttcagttaac tagccttaaa
    31681 agtgagctcc agttgcgtat ctttgttacc tttttctttt taagttacta cggaagacgc
    31741 acgttgccat ttccaatcga aaaaaagaag atcaaagaaa ttatggtcaa gaataattgt
    31801 cagatgaatt tgtttcagga agaaagccca tatgagcaat ctttctttat tatgtatttt
    31861 gttgtgcatc tcatgagaga atcccaagga actccatttg aatggaaagc tggagactct
    31921 tatgtacagt tgataaatat cgataaaaaa gacttcttaa tcttgaaaaa tctcttagga
    31981 aaattgaagt acagcagcta tataaaagta gtgaactatt ttgtcaatac gattttttca
    32041 gaattttcgg agaaagaaaa aaatgaaatc agtgagcaga tacgaaaaaa tatgtcctac
    32101 tgttcgtttt catccgctga ttgcaaagaa aaaaacgaag aatatgttgt tcaattatta
    32161 acgcaaattt attttttctc ccgtattttc ccatacgata cgactcattt gacgatccgt
    32221 gcaacttact ttgcacagca gatgcaacac cgccagatac gtctatatgc tggatttcgt
    32281 gcagaacttc aattttattc cactctactg aatcagaatc tgatttatta tttatctagc
    32341 tatatctttt ggatgcttat cggtaatcct gaaattcacc attatacttc tgataaaaaa
    32401 atactgatta tcagcgactt aagtcttcga catagtcaat atattgaaga atatatcagt
    32461 gatattcttg ctgtgcataa aattcactct gagacaactg ctattactga agatcagctg
    32521 tcgaaataca atcttctcga gtatgatctg atcgttacga atcaacccat tttgaatgcc
    32581 catgttcctc atatattgat tgatgatagt gtgtcattcg caaatgaaga agaactcatc
    32641 cgcttattcg agttatgaat aatcaaaaaa cagctatgta taaaccaccc tgataaaaat
    32701 ttcaggacaa atacacatag ctgtttcttt ttattgtatt ccttcagcaa tccaacgaga
    32761 tttatagcga aagtctttta acaactcttc ttttgtccaa ttatttgcaa tgagatccgt
    32821 caaagtgttc attacgaggg tcatggaaaa gtataggaaa ctaactgctt cttccgacga
    32881 ttgaatggag aaatgattga ttcttaataa ttccagccat ttttcgttca ttggagaatc
    32941 agccgatagt tctctacgtt tggttgtctg ctgatcattt cgctgggtta acaagtataa
    33001 cctttgccaa tagatacttt cgtgatctaa gtcgcagcac cactctaaat atttttcgat
    33061 ccccaaaaag aaatgttgtt tgttttcgct aatgaatttt aagatatctt gatggactat
    33121 gtgagaactg cttttgatcg tatacaaata agcatcttcc aaatcttgaa aatatttata
    33181 aaaagcaccg cgcgacatcc ccatcttgtc aacgatttct gagactttga cttggctgat
    33241 gtgctgtgag caaaatatct ccagtaatag gtcatcgatt ctctgtttct ttgcgttcga
    33301 taaattgaaa aaagtttctt ttggcatcca catctctcct ttatctctga ttatacgtgg
    33361 atagcccttc attgtcatga aggattcatt ccttcttttt ctcttcttct gtcaagtacc
    33421 catcttccat tcgataaacg cgatcactcc attgaatcat acggacatca tgagtaacca
    33481 taatagtcgc tttttgtttc tcatgagctt ctttaactag taatttgacg acttcatatg
    33541 catgatctgt atccaaacta gctgttggtt cgtctgctaa gatcaagctt ggctcattat
    33601 ataaagcgcg agcaattgcc actctctgtc tttctccacc agaaaggtct ttaggataac
    33661 tatttttaag tgactggata tctaaagatt gcagcaagga atcgattttt gttgaatctt
    33721 ctttttttga agtaacttgg tcaactagtt caaattgttc ctttaccgtt aaaaaaggaa
    33781 tcaaattaga gctttggaga ataaatccta tttctttaaa gcgtaaatct gctcgttttt
    33841 tttctggaag ctcagttagt gagtgaccgt tgatcactat ttctccggaa gtcggtgttt
    33901 gcaatcctcc tgaaatggta aggaaagtac ttttacctga accagaagga ccaatgatgc
    33961 tgacgaattc tccttccttt acataaaaat caattgcttt caaagctgag acctttgtat
    34021 gaccagaacc aaatgttttg gtaacttttt tcatcgttaa tatttttttc atttttatta
    34081 acctcctatt gctgtaattg ggtctacttt ggttatcgta cgtatcgaaa acaatccgcc
    34141 tagcattgcg acaatgatca aaatcccact atatagcaac cattgtgacc aaaaaacagc
    34201 aaaaggcatc gcgcttggta aaatcagact agtcaaataa gcaaacaaaa gagcaagcag
    34261 aacgcctacc accccaacaa taaaggactg tgctactaaa gatttagcga tgaagaaatt
    34321 tttgatccct tgtgctttca ttactccaaa aatagcagtc ttctgaagtg tcatcacgta
    34381 catgaaaata ccgaccacgg cagcaaccac taagaacaaa aagtatatca tcgcatttaa
    34441 ggtcatattt tgggcagaat agccaggaat actttcaatg aatgtcccaa tagttaataa
    34501 ctgtagaccc ttcgatgctt tttctttcga aattttagct gaatccttta ttacgatccc
    34561 attgatcggc tgttcttctt cagaagcaaa cggctgttgt ccatacttca aagcagtcca
    34621 cgtatctagg gacgcataga tgacgggaga aactgtgtaa taagtttcag gaaagatacc
    34681 gacaatcgtc aaaggatcgt cgtaactgcc aattttgatc gtatctccaa ttttatagcc
    34741 tgaatcagcc agattttgag agatgatgat ttcattcttt gttttaaatt catgcccttt
    34801 cgtgagtttt ggtaataaaa atgcttcttt cgttgtgccg aaaactgtaa cattttcttt
    34861 gttttttcct ttgattgctc cgctgtacaa tccgattggt gctttctctc ctccttcaat
    34921 gtatttcaga tctcctcttg ttaattgtga agctgcaaat acttgatttg catcctccga
    34981 caaaacaatc tcttgtgcgt cccaatcatc gattgctttt ttaaactctt ctgaaagtcc
    35041 attcgctagt cctgacaaca tgaatacgac atacgcaatc aagaacataa taccgacgat
    35101 caagccatat cgtaatttag aatagcgaat ttctttgata gctagaaaca tttgtttttc
    35161 ctccctatga tagattgata gtgacaaaat gtcacttgtt gaatagtgta actctaaagt
    35221 gacaatttgt cacttgtgtt gtttttttct tatcaataaa ttgtctaaga catctttcga
    35281 taaaacctta acatgagtca taaaaaattt atttaagcct tatttatgct ttccatgata
    35341 aactaaagtg accaaatcaa tgaggtggga aaatgattaa actattagta gtagaagacg
    35401 ataaagtatt atccaataat ataaaagaaa tactcgctgc aatcggcgag ataacacaag
    35461 tttatgatgg tagtgaagga ctgttcgagt tggaaagtgg agtttatgat cttgcaatct
    35521 tggatttgat gatgccggaa atgaatggat atgaagtgtt agcaaaaata cggaaagaaa
    35581 aaatacagac tccagtattg attttgactg caaaagatag tttggaagat aagattgaag
    35641 gatttgaacg aggtgcagat gattatctaa caaaaccttt ctatcgagaa gaactgatca
    35701 tgcgcgtgaa agcattattg aaacgctcgc taggtctctt tgatgaaaat gttctgaagt
    35761 ataaggatat cagttgtgat ttaaaaagca atgaagtctt gtataaagaa caagttttgc
    35821 ccatacaagg aaaagagttt gaattgctcg tttatttttt acaaaataag ggaatcattt
    35881 tgacaaaaga gcagatattt gaccggatct ggggatttga ttctgatacg acgattacag
    35941 ttattgaagt ttatatgagc aacttacgaa aacatctgcg aagtactgga ttggataaag
    36001 aaatcaaaac cttacgtaat gtcggttata tactgcaaag ggtgtgatgc aatgaatgga
    36061 gatattacac gaaagcaacg tagtcgcttt tttgcgacaa atgtagcagc atttgctttt
    36121 atcttttttc ttttgggatt cattacttta cagatattaa accaatctgc atacagagaa
    36181 acagatctgt cattagagaa aataaatttt gattctcgaa cagtacaatt agagatacaa
    36241 agatatcagc aaggcgatcc ctttttaaac ccgactcaaa cggaacaaaa cagaacaaac
    36301 atggaacagc cattaatgga accatcaaat gaccgtttta acactcaagt gatcttgtgg
    36361 tctaaaaatg gtgagatatt gaataaagca gctattggtg ggcgtttcaa ccaaatcaaa
    36421 gaattaaaaa tggatacgaa aaatctgaat accatccaaa atattgaatt aaatgaagac
    36481 agtggctcat ctgccctctc tttccgttcg attacgaaaa aagcggagac gaatcaagat
    36541 ggcgttgcct acatccaaat tttagaaaat acaaatcaaa tcaagaattc attagcgact
    36601 tttcgcacga ttatgatttt gtgtatgatt gttttttgga ttctctctat tggtatcagt
    36661 tattacttgt ctagtctaag catgcgccct attattcttt cttggagaag acaaaaagaa
    36721 tttgttgaga atgcttctca tgaattgcgc acaccgttaa cgattattca aaatagtttg
    36781 gaacatcttt ttaccaagcc taatcatact attattgaag aatccgaaag catcgctcaa
    36841 gcattgtcag agacgaggcg cctcactgga ttgacttcgg atttgctgac aatcgctcgg
    36901 aatgattctg atcagcagct gctttcaaag caaatgatca atacacaaga atatatcgaa
    36961 caacttgtta aaccatttca agagatggcc atcatagatg gaaaagagtt tattctccat
    37021 aacgatgcaa cattagaagt accaattgat gaaaaaaaaa tccatcaagt tttggttatt
    37081 ttgctggata atgcattaaa atatacgaat ccagaagata agatcatttt ggattcatct
    37141 gttaaccata aagaatggct gattcacgta aagaatactg gcccttctat cagtgaagaa
    37201 gatcaagcaa ggatttttga tcgattttat cgggaagatc aatctcgggc gaaagagact
    37261 ggcggatacg ggcttggctt ggcaattgca aaacaggtaa tcgaacagca tcatggacag
    37321 atttctgtat ccaattatct tccacaagga gtcgatttta aagtccaatt gccgttgaag
    37381 cctaaaaaat aatgcttatc cctaaaaaag ggctgtgaca aaaatcttgt cacagccctt
    37441 ttttgttgcg aataaacggt gttccagaag tagcttcttc ggaaataagc cgaaatttct
    37501 ttaagctgac cacttctgtc acaacctctt tagcttacgc ttacgatttt ttattgcggt
    37561 cttcaatgtg tacatcaccg cttgtgtcaa tatccaattc ttctcggcta acatcttctg
    37621 tcactttttc aacatcttca tgttcttctt tatgaatccc aacttcttca cgaataactg
    37681 tatgtttgct tacatctact tgctcttctt tgattgggat agtaatcgtg tcatcttcca
    37741 atttttcgtc tgttccctgt gaagattgat ctgttactgg tttgcgttcg atgacgattt
    37801 cttcacgttt gaccggtact tctaccgttt cagtatcgtt gaccacatgt ttgtggatgt
    37861 cgacttctcc agttgtcaca tcatgtgtat ttacatctaa tttttcttct tttagttgaa
    37921 ttgtatcatc atctagattt ggtttgcgat cgatgtcttc agtcttgctt gtacccattg
    37981 tatcagtctc gccaggtacg tccatcggat cagttcctgg tgtcatattc aatggatccg
    38041 ttgtattttg aaagcctgtc gtgccaccta cgtccattgg atctgttcca gtgccagttt
    38101 ctaatccagt ccccattgtg cttgctgggc taacagtatc ttgtgtatcc attgtatctt
    38161 ctgttgtttc tggctgacga tagcctttta ctgtgatgac aaattttcca tcagaaatat
    38221 ctcctctata ttgatataaa ggatcatttt ctggtgtagc cgtctcagaa tcataggtat
    38281 caaaagaaaa agtatctttt attttttccc ataaagaacg gtcttcttca ccatccatcc
    38341 gattttcatc tgtttcaaca tctataccag acaatccgtc aaatcctagt ctagatgctg
    38401 cttcatcagt agtataaata acgatatcat ctcgttcata cccttcgtta cgcaaccgtt
    38461 caattactga taatgcttct tccctcgtac tatagcttcc gatgaccgtt aaatttttct
    38521 cttccatgta aattcctcct agcaaataga tttatgattg gtatattgtt acttataaat
    38581 ttattctata ggagacgatt gttttctaca aatatttaga ttggaatttg attaaaacaa
    38641 tttaattgaa atttgaaaac atttatgtta atgaaagtca tattctaata aaatgtcatt
    38701 tgtttctata tgaattttta tgaaaaattt catataattt ccactcgttg tgatggttta
    38761 atttatccaa tccatcaata agcaaacaac ttatataaaa aaggattaat tctcaatata
    38821 attgctccta ccatagaata aatcttcatg taaagtaatg aagtaccaac tatttctaat
    38881 acttctttaa gaattatccc aacaatatcg ttagacaaac cattattgaa taaatggaga
    38941 gccaatcgat tctgaaaaaa tgttttctaa tttttcggaa ataaaagaaa gagcctcctg
    39001 ccattagaac gaaccaaatc catttcattg ctcatgaagt aaccacatag ctaaaaagag
    39061 gataaatcaa ttaaaagatc aaaagaatga ctgcactaat aaaataacta aaaatgtatc
    39121 ttcttacttc atatctttta gctagtactt agttaaaaat ttgcttccta agatcaagac
    39181 aaactgtcta tcttcatttg atgaaatgcg gtaaaatata gaaaatgaac actattggag
    39241 ggaatttgta atggacagca aaactagaaa acaactgcaa gaaaagttaa agcaacgtac
    39301 acacttgctc ccttccgtct ttcaacagtt tttagaagaa aatcgttctt ccctttcatt
    39361 aggcagtcgc tatgaatacg caaaagattt tcatctgttt actgattatt tgagaaaagt
    39421 attttctgaa gaagtggatg atcagctgat tatccattta gaaaaacaag attatcagaa
    39481 tttcttagct aaaatctatc gacatactcg ttcgttccaa actacagcga accaagaaac
    39541 ggagcaattg tttgaaaata gctattacgg gatttcaagg aagcaatatt cattaaatca
    39601 ttttttacga tttttgtatc aaaaaggact gattgaagaa gagatttctc ttttgggtac
    39661 aagtttaccg gaaacaacca aagcagctcc gcgatatatc gatgcagaac ttttcaaaga
    39721 ttttgagcat ttgtttatcc cgattgaagg ctttcaaaca agcagagaag ctagctttga
    39781 agaaaagaat agaccgagga accttgcaat tactgccatt cttctgtatt gcggattaaa
    39841 gatccatgaa gtagtagaac ttaaacgtaa agatgtatct ttgaccaagc agattcttaa
    39901 tctgaataga aaagaaaaca gactgaataa agtaccaata ccaaaagaag cgatgccatt
    39961 tctggagaac tattttaagt taacagcaca aaatacggac gaaaattctt ttgtttttcg
    40021 ttcctcacat gatcagcaaa tttctcctcg gactattcgc caaattttga gcaaaattac
    40081 agtatataaa aacgtatcgc cagaactatg cagaaaaaca tatcgttatt atgcagaact
    40141 atatttagat gatgctgacg cggtaaatta tttatgtggt aatcgatacc tctcatccca
    40201 ttcttttcaa gatatctggg aaaagatggt tgatttttct tatcacgaat tagcggcatt
    40261 cgttcgggtt tcttccatat aaaacaaatg tatgatcttt ttttcacaat aaactatgtt
    40321 attatataaa ggattatgtt acgattatct tgaatttgta tattacttaa caaaagataa
    40381 tggagtgtga atgatggaga ccataacgta ttcccctttg aacttattta cgaattttca
    40441 agaagctgca gctaactttt ccgagacccc gattatcttt gatgagccac tttcagcttt
    40501 cccagaatta ggacttgaaa caacttacaa aaaatgctgc gaaagtgtgt tgaaacgggc
    40561 ttatcaattg gctcatcttg gagtgaaatc cggagacaaa gttattattt ataagagttc
    40621 cgcttttgac acataccttc tagctgtttc tgtgtcttac cttggtgcag tgcctgtcat
    40681 gacttcttat catctaccaa caacaacaat ggaagtattt atcgatcgtt tagaagaccc
    40741 tttcatttta tttgatgatg agacaaaaaa gcgagtgaga gaaatttcaa atggaacaaa
    40801 atcaaaacag attcctaacc cgtggtgcta gt
//
LOCUS       DAMEEU010000019        36619 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.020, whole genome shotgun sequence.
ACCESSION   DAMEEU010000019 DAMEEU010000000
VERSION     DAMEEU010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36619)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36619)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36619
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.020"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            14..1675
                     /locus_tag="PB779_001004"
     CDS             14..1675
                     /locus_tag="PB779_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0738543.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(1745..2092)
                     /locus_tag="PB779_001005"
     CDS             complement(1745..2092)
                     /locus_tag="PB779_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HDE0738544.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSTLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            2176..3117
                     /locus_tag="PB779_001006"
     CDS             2176..3117
                     /locus_tag="PB779_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738545.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKNQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            3118..4161
                     /locus_tag="PB779_001007"
     CDS             3118..4161
                     /locus_tag="PB779_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738546.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            4167..5237
                     /locus_tag="PB779_001008"
     CDS             4167..5237
                     /locus_tag="PB779_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738547.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            5227..6180
                     /locus_tag="PB779_001009"
     CDS             5227..6180
                     /locus_tag="PB779_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738548.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            6192..7202
                     /locus_tag="PB779_001010"
     CDS             6192..7202
                     /locus_tag="PB779_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0738549.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(7487..8308)
                     /locus_tag="PB779_001011"
     CDS             complement(7487..8308)
                     /locus_tag="PB779_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HDE0738550.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(8405..8683)
                     /locus_tag="PB779_001012"
     CDS             complement(8405..8683)
                     /locus_tag="PB779_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738551.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            8951..10960
                     /gene="metG"
                     /locus_tag="PB779_001013"
     CDS             8951..10960
                     /gene="metG"
                     /locus_tag="PB779_001013"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HDE0738552.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(11439..12026)
                     /locus_tag="PB779_001014"
     CDS             complement(11439..12026)
                     /locus_tag="PB779_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738553.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            12201..13523
                     /locus_tag="PB779_001015"
     CDS             12201..13523
                     /locus_tag="PB779_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0738554.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            13678..14454
                     /locus_tag="PB779_001016"
     CDS             13678..14454
                     /locus_tag="PB779_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDE0738555.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            14447..15016
                     /gene="rnmV"
                     /locus_tag="PB779_001017"
     CDS             14447..15016
                     /gene="rnmV"
                     /locus_tag="PB779_001017"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HDE0738556.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            15009..15893
                     /gene="rsmA"
                     /locus_tag="PB779_001018"
     CDS             15009..15893
                     /gene="rsmA"
                     /locus_tag="PB779_001018"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HDE0738557.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            16344..16973
                     /locus_tag="PB779_001019"
     CDS             16344..16973
                     /locus_tag="PB779_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738558.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(17097..18206)
                     /gene="ugpC"
                     /locus_tag="PB779_001020"
     CDS             complement(17097..18206)
                     /gene="ugpC"
                     /locus_tag="PB779_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HDE0738559.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            18415..18837
                     /gene="mgsA"
                     /locus_tag="PB779_001021"
     CDS             18415..18837
                     /gene="mgsA"
                     /locus_tag="PB779_001021"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HDE0738560.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            19160..19696
                     /locus_tag="PB779_001022"
     CDS             19160..19696
                     /locus_tag="PB779_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HDE0738561.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(19736..21499)
                     /locus_tag="PB779_001023"
     CDS             complement(19736..21499)
                     /locus_tag="PB779_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738562.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(21502..23217)
                     /locus_tag="PB779_001024"
     CDS             complement(21502..23217)
                     /locus_tag="PB779_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738563.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(23996..24220)
                     /locus_tag="PB779_001025"
     CDS             complement(23996..24220)
                     /locus_tag="PB779_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738564.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            24411..27188
                     /locus_tag="PB779_001026"
     CDS             24411..27188
                     /locus_tag="PB779_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDE0738565.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            27269..27688
                     /locus_tag="PB779_001027"
     CDS             27269..27688
                     /locus_tag="PB779_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HDE0738566.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            27700..28170
                     /locus_tag="PB779_001028"
     CDS             27700..28170
                     /locus_tag="PB779_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0738567.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            28187..28966
                     /locus_tag="PB779_001029"
     CDS             28187..28966
                     /locus_tag="PB779_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0738568.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            28953..29774
                     /locus_tag="PB779_001030"
     CDS             28953..29774
                     /locus_tag="PB779_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDE0738569.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            29791..30840
                     /locus_tag="PB779_001031"
     CDS             29791..30840
                     /locus_tag="PB779_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0738570.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            30853..31857
                     /locus_tag="PB779_001032"
     CDS             30853..31857
                     /locus_tag="PB779_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0738571.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
     gene            32490..33509
                     /locus_tag="PB779_001033"
     CDS             32490..33509
                     /locus_tag="PB779_001033"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDE0738572.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
     gene            33552..34433
                     /gene="galU"
                     /locus_tag="PB779_001034"
     CDS             33552..34433
                     /gene="galU"
                     /locus_tag="PB779_001034"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDE0738573.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            34733..35110
                     /locus_tag="PB779_001035"
     CDS             34733..35110
                     /locus_tag="PB779_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738574.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            35716..36330
                     /locus_tag="PB779_001036"
     CDS             35716..36330
                     /locus_tag="PB779_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0738575.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
BASE COUNT        11962 a         6431 c         7523 g        10703 t
ORIGIN      
        1 aggggtacgt aaaatgaaaa agaaatttac atttggtttg gttgcggtat gcggccttgt
       61 acttgctgga tgttatggcg gcagttcagc cacaagcagt agttcagcaa aaagcggttc
      121 agcagatgga ggaggcgtat ttaacttagt cgtgcctcaa gaaatgccta cagctgactt
      181 atcagttgca acagatacaa tcagttttac agcattgaat aacgtttatg aaggaattta
      241 ccgtcttgat gaagacagca aaccacagcc ggcaggagct agcgagttgg cagaagtcag
      301 tgaagacgga ttaacttaca aaatcaaatt acgagaagac gcaaaatggt caaatggtga
      361 tcctgttaca gcagcggatt acgtttatgg ctggcaacga acagtagacc cagctacagc
      421 ttctgaatat gcttacctgt atgcgccagt tgaaaatgca gaagacatta cagctggaaa
      481 gaaagataaa tcagaactag ggatcaaagc agttggtgac tatgaattag aaatcaaatt
      541 gacgaaacaa acaccatatt tccaatatct gcttgctttc ccatcatttt tcccacaaaa
      601 acaatccgta gtggaagaaa atggggatgc ctatgcatct gcaagtgata aagctgttta
      661 taatggacca ttcacattag aagattttga tggaccagga acagatacag aatggactta
      721 taagaaaaat gatcattact gggacaaaga tacagtaaaa ctttctgaaa tcaaagtcag
      781 tgtagtaaaa gaatcttcta ctgcattgaa cttattcaaa gatggccaag cagatgacgt
      841 gatcttgtct ggtgagttag cacagcaaaa cgcaaacgat ccagcttata cttctgttaa
      901 agaagcgcgg acaagctata tcgaattcaa tcaacgtgaa aagaattcac cattcaacaa
      961 tgtgaaccta agaaaagcta tttcttattc tatcgatcgt gaagctttag taaaacaagt
     1021 actaggtgac ggatcagttg tctctacagg attgatccca tcagatatgg taaaaagtcc
     1081 aacaacgaac gaagactttg caaaagaagc tggaaaatta gtttcttatg acaaagataa
     1141 agcaaaagaa tattgggaaa aagcgaaaaa agaattgggc gttgattctt tagaatttga
     1201 tttgatggct tctgatgatg attcatcgaa aaaagtaatc gaatatgttc aaaactcaat
     1261 ccaagaaaac ttggatggcg taacagtcaa accaacacct gttccattct ctgtacgtct
     1321 tgaccgctca acttcgggtg attttgacgc agtactaggc ggatgggctg ctgactatgc
     1381 agacccaagc agctttactg atttgtttgt cacaggtaat tcatacaacc gtggtcgctg
     1441 gagcaatgca gaatatgacg aagcagttaa agcagcttca tcaacagacg ctggcgatga
     1501 acaagcccgt tgggatgatt tccaaaaagc aatcaagatc atctctgatg atatgggtgt
     1561 cgttccggtg taccaaaaag cagaaggtca cctagtgaat gaaaaaatca aaggtatcgt
     1621 tcaccatgcg gcaggcgctt catgggatta caaatggaca tacgttgaag aataatcgtt
     1681 aataccgtga gcatgagaaa aaacgaggct gcggcaaatg tcgcaacctc gttctcatat
     1741 tcacttatcc taacaaagaa aaaagcatga aaatagcaga aagagcaatt agtattccgg
     1801 caatgatcag ccaaaagctg tacataccgt agctggcaga cgagagcgtg gaaaattctg
     1861 gttttttctt tcggttcctt gttcgtgcaa gatggaccga tcgctgaaaa tgatcgaaga
     1921 aacccgaaga aaagacccat aaaaaaccgc cgataatcag aaacggcaat gaccataaga
     1981 atagatcatt agataattga atgagtgtaa aggaatggtt gatgagattt tttattaaaa
     2041 taaccagaat cagtagaaaa gctactgcgt aggggataga tttttttttc atttgattgc
     2101 tcctttattt ttggttcatt atctaataat gtagcgaaac atctgtcaga agtcaaaagc
     2161 tagggggaaa cattagtgaa tagttatatc aaatatgtat taaaacgtgt ctttttcatg
     2221 atcatcacgc tttggttaat tgcaacaatc acctttttct tgatgcaatt gctgccgggc
     2281 acgccatata cgaatcagga acgtttgagt cctgaaacaa tcgagatgct aaataaacaa
     2341 gtcggtttgg ataaaccagt tatcgtacaa tatgggattt atctttctaa tttgcttcaa
     2401 ggagattttg gaatttcctt ccaatttaaa aaccagccag tcgcacattt gttagctgga
     2461 agaatcggac catccttgca gttagggtta caggcaatta tctttggaac agtcctaggg
     2521 acgattttag gaacgatctc tgccatgaag caaaatacat gggcagatac atcttctaca
     2581 ctcgtagcga tattaggtcg ttccattcca aactttgtat ttgctgtttt attacaatat
     2641 atctttgcaa tcaaattaca agttttgcca atcgcaaaat gggatggctt tgtgtacaca
     2701 atcttaccaa caattgcgtt ggccatgtcg ccgcttgctg actctgctcg gtttatccgt
     2761 acggaaatgg tggaagtact gcatagtgat tatgtggaat tagcaaaagc aaaaggattg
     2821 agccgttggg aaatcgcctt taaacatggt cttcgaaata gtttgattcc attgatgact
     2881 ttattaggac cgttagctgt agcattgatg accggatcac tggtggtaga aaatatcttt
     2941 gctattcctg gtatcgggga acaattcgtt aagtcaatca caacaaatga ttatcctacg
     3001 atcatggctg taacgatcct ttactcattt atgctgattt ttgttatttt gatcgtggat
     3061 ctattgtacg gtctagttga tccaagaatt cgtgtttcag aagggagccg aggataaatg
     3121 gaaatgatac caaagcgtta tgaaacagtt gcagatatcc ctgcggatga atttcttcca
     3181 ttacaaaaaa ataccgaaga agaacgtgaa cagattactg caccttcttt gaattttatc
     3241 caagattcat ggcgccgttt aaagaaaaac aaagctgccg ttatttcaat ggttttacta
     3301 ttggtcatca ttttgatctc tgtgatcaca atctttgttt ctcctcatga tccaactgcc
     3361 caaaacgtgg cttatatcaa tttgcctcct cgtattccgg gaatcaatat cgatggattg
     3421 aatggaaaag caatggttgg tggtgaactt gttgataaat atgctcaagc aaacgtccct
     3481 tcaaacgtaa atttcttttt aggaacagac ggtttgggac gtgatgtatt aagccgctta
     3541 tttatgggaa tgagaatctc gttgctgatc gcatttattg ctgcattact agatgtaacg
     3601 attggtgtag cttacgggtt ggtttctggt ttgttaggcg gacgtgtcga taacgtgatg
     3661 caacgttttt tggaaatctt atcaggaatt ccaaacctcg ttgtcatgat tttgatgttg
     3721 gtcgtttttg aaccaggaat tttttcaatc gtggctgcta tggccatcac aaactggata
     3781 ccaatggcac gtatcgttcg tgcacaaaca atgaaattaa aagatcaaga atatgtttta
     3841 gctggattga cattaggtga atcaagaatg aaaattgcat tcaaacatat tttgccgaat
     3901 atctctagtg tcattattat tcaaatgatg tttagtattc catctgctat tttcttcgaa
     3961 gcctttttaa gctttatcgg tttaggtctt acgcctccgt cagcttcatt aggaacgatg
     4021 ttgagcgaag ggtacaagac attcctgtat ctgccttatc tattatggat tccggcagta
     4081 actttatcgg ttatcatgat tggctttaac ttacttgctg atggattgcg tgatgccttt
     4141 gatcctaaaa tgaaagagtg aagacgatga cgaaaatttt agaagtgaaa gacttagaaa
     4201 tctcttttga tacgtatgct ggaaaggtac gagcgattcg cggtgtcaat tttcatttga
     4261 ataaaggaga aacattggcg atcgttgggg aatctggaag tggaaaatca gtgacgacca
     4321 gaagcatcat gcgcttgctg tcaagcaacg ccaatataga tgctggtcaa atcctcttta
     4381 aaggtaacga tatcgttgga aaatcagaaa gagagatgca aaaaatccgt ggtaaagaaa
     4441 tagcgatgat tttccaagat ccaatgacct ctttagatcc gacgatgccc attgggaagc
     4501 aagtcgctga gtcccttaga aagcataata aagtttcaaa aaaagaggga caaaaagctg
     4561 cattagaatt gcttaaatta gttggaatac ccgaagctga gaaacgtatc aacagttatc
     4621 cgcatcagtt ctcaggaggt cagcgtcaac ggatcgtgat cgcgattgca ctggtatgtt
     4681 atccggaaat cctgattgct gatgaaccta caacagcgct tgatgtgact attcaagcac
     4741 agattttgga gctgctgaaa gaaattcaga caaaaatcga tacatcaatt atctttatca
     4801 ctcatgacct tggtgtagta gcgaatgtcg ctgatcgtgt cgctgtcatg tatggaggaa
     4861 gaatcgttga agttggaaca tcggaagaaa ttttctacaa cccgcaacat ccctatactt
     4921 ggggactgct tggttcaatg ccgacattag atagtgcgaa cgatcgattg tatgctattc
     4981 ctggttctcc accggattta ttgaacccgc caaaaggaga cgcattctat ccaagaaatg
     5041 aattcgcgat gaaaatcgat gcagaacaag aaccaccatt ttttgaacta tcaaaaacac
     5101 acaaggcagc aacttggcta cttgctccgc aggcacccaa agtgacaccg ccagaagaaa
     5161 tccaacgtcg ctgggctatc tttaaagaga aacaaaaaca tacttacggt caaggaggaa
     5221 ttgctgatgc caaataaact acttgaagtt aaaggattga aacagtattt caatgtagga
     5281 aaaaagaatg aagtacatgc tgtaaatgac atcagctttc acatttatga aggagaaaca
     5341 ttcggtttag ttggagaatc tggaagcgga aaatccacta ctggccgtac gatcattcgc
     5401 ttgaatgaac ctactgatgg tgagatatta ttcgacggtc aagatataac gaagatcaaa
     5461 gataaaaaag gtttgacgaa attccggcat gatgttcaga tgatctttca agatccatac
     5521 gcttcgttga atcctcgtat gaaagtcaga gatatcattg ccgaaggaat tgatgttaat
     5581 ggactagcta aatcatctga agagcgtgca aaaaaagtcg atgatctatt gagaactgtt
     5641 ggattgaatc caagccacgg tactcgttat cctcatgaat tttcaggtgg gcaacgccag
     5701 cgtattggta ttgcacgagc attggcagta aaaccgcgtt ttatcatttg tgatgaacca
     5761 atttctgcac tagatgtgtc gatccaagcc caagtggtca atttgttgca agatctccaa
     5821 aaagaacatc aattgaccta tctatttatt gcacatgatt tgtcgatggt taaacatatt
     5881 agtgaccgaa tcggtgtaat gcataacggc ttgttattag agatgggaac aagtgatgaa
     5941 atctataatc acggtgttca tccttataca gaaagtttgt tatctgctat tcctctacca
     6001 gatccagacc atgagagaaa acgcagaaga atcaaatatc aacctgaacc agatgacgga
     6061 caagtacgtc aacttcgtga aatcgcacca gaacattttg tctatgcaac tgagcaggaa
     6121 gtcccatatt acgcaaaaaa actaaaacga caaaaggaat ctcttctggt tgctaactag
     6181 gagggacata gatgctaaaa gcttttaaat tccgtatgta tccgacagaa gaacaaaaac
     6241 agcaattgat tcgtactttt ggatgtgctc gatttaccta taaccatttg ctgaaaaagc
     6301 ggcagaaaag ttggcaacaa acaggagtag ccaatttttc gctcacaccc gctacattaa
     6361 aaaaagaata cccattctta aaagaagtag acagtcttgc tttagcaaat gcacagctta
     6421 atttggatcg ggcttttcgc aattatttca agggacgtgc cagcttccca aagcttaaaa
     6481 cgaaaaaaag tatgtggcaa tcttatacga ccaacaacca aacccgtacg atctatctgg
     6541 aaaatggcta cttaaagtta ccaaaacaaa aagaactaat caagataaat cagcatcggc
     6601 cagttgaagg atcgattcgc tccgctacga tttctgctcg atataatgaa gaattttatg
     6661 tcgcactact ttgtgatgtt tcgccagtaa aaaaagaatc tttagctaaa tggatcggga
     6721 tcgcctatca tccgaagaca ttgatccaaa catctcgacc tctagaagta actttaccaa
     6781 aatttcacca gacagaagaa aagctgcaac atgcacagcg gaaattgaat gtgaaagtcc
     6841 gctccgctca ccatagaaag atcaggttag atcaggcaag caattatcag aaacaaaaga
     6901 gaaaagtaat ggatctttat ctgaaacaaa agaaccagcg agaagattat cttgaacaat
     6961 tatctgggaa attggtcaaa caatatgact acttatttgt agaatctttt ccaaaagaag
     7021 aggcacatgc tgatttttct attcacgact ggcataaatt aataacaaaa ttgcgttata
     7081 agtcccaatg gtataataaa aaatttcttt tgatcaatac cgacggagca gaagaaagca
     7141 attccgtaag aaagagccaa gtagtagaaa aaatgggcag acattcggtt atcaagggat
     7201 aaaaaatgaa tgaaactgat aggagcgtta gggttagcct tgttaataaa aagtcttaat
     7261 gacttttgtt tctaggaatt tttcttttga agaaaagctc actaattatg acaaaccaat
     7321 aaaacaatag cagaaaaagt tcgtacgagc tttttctgct attgttaatt ttttattcag
     7381 aaagtttacg aatacatcaa aattctgaaa caaaaaacgt aactcacaaa gagttgtttt
     7441 tgcgtttttt cttgaatgat taggtctgaa tcttttgctc acaaccttat tcatggtgcc
     7501 ccggcttgag ctgatagatt tttgaaggac ggccgattcc tacaggacgt tcaccgatct
     7561 catcgaaata ttggagcata gctttcttaa aattggaatg atcgatcgtt ttataatcga
     7621 tccctaagaa tttagcaaat acttttcgag cttccgtaat cgtgaaatct ttacctaaaa
     7681 cttgtagaac ttgcggctcg tgttccattt tattgactac acggttgaat gctttcaaga
     7741 tgatttgact atggtcaaaa gccaaagtat ctttgccaga agactctcca gtgactaaat
     7801 caagcgagat agccacttct ccgctagata aatggatctt gttactatga cgttctagtg
     7861 tgaaccagcg tacttccttg gcatcatctc cggcgattag cggttcttct ccaataaagg
     7921 ctaagtagct gactgtgacg acccagcctc gcggatctcg attaggcgta ctgaatgtat
     7981 gcagttgctc aatattttct tttgaaataa ccacaccagt ttcttccttt gtttctctta
     8041 agacgctttc tccagttgac tcatcctttt ggacaaagcc accaggcaat gcccatgaat
     8101 ttcgataagg atgccctttt ctttggatca acaaaacttt cagctgatct tcttctttgt
     8161 tatagcacat cagtacgata tcgacagtca aagagggctt gtcatattct ggacgttcct
     8221 gtttttgata ccagttaaga aattcttctt cacttgcttt atgttcataa tataattttt
     8281 cttcttcttt agaagcaaaa cggttcatct gaccacctcc attgacagta aaagtacttt
     8341 ttaccttatt gtagcagact ctgaaaaaaa accaaggatt tacttgaaaa atctaggtta
     8401 tcatttaaat atgaaaaata aatggaagta tgagattgaa taaaaagaaa agcagataaa
     8461 acggcaatac tttataccgc tcttcacgaa tggcaaagaa gccacaaata acgatatata
     8521 cgtcaatgat aaaacgcaaa atccaagctg ctgtcataaa actgttcaaa tgcccatgga
     8581 ggttaaaata accatacata cgaatataaa aatagctgaa tattaaatgt gctaatgaaa
     8641 gaaaagcaat actaagtgta aaaaaaagat gtttcttctg catgattgtt ccagtccctt
     8701 actaagatag atagtcttta ttataccacg tgtgagggga gaaataaaaa gccgtttttt
     8761 agtagatatg aaacaaaaca aaaacccgca tttattcaac ctattcatcc ttttaaagga
     8821 tagattgaac gtagatagaa gtcgtttatc cagtcttttt cattttgaaa aaaagctaac
     8881 agcatgcttt ttttatggta tactagcaag gaaacgaatt cgcatcatgc gataaaggag
     8941 gaagagcccc gtggcagaaa aggaaacttt ttatatcact acgccaatct attatccaag
     9001 cggcaaactt catatcggca actcgtatac tacgattgca tgtgacgcaa ttgctcgtta
     9061 taaacggttg atgggctttg atgtgtttta tctcactgga gtggatgaac atggtcaaaa
     9121 aatcgaaaca aaagcagaag aactaggtgt aaaaccgcaa gaatatgtag ataaaatggc
     9181 ggctgatgtc aagaaattat ggaaaacgct tgatatcagt tatgataaat tcattcgcac
     9241 gacagatgat taccataaag cagctgttca aaaaatattt gatcgtttat tagaacaggg
     9301 agatatttac ttaggtgaat atgaaggctg gtactctgtt tctgacgaag aattctttac
     9361 agaaacacaa cttgcagaag tgtacaaaga tgacgaaggt aacgtgatcg gtggtaaagc
     9421 gccaagtgga cacgaagtag aattggtaaa agaagaatca tacttcttcc gcatgagcaa
     9481 atacgcagac cgtctattgg aatactatga agaacatccc gaattcatcc agccagaatc
     9541 tcgtaaaaac gaaatgatca acaactttat caaaccagga ttagaggatc ttgcagtttc
     9601 acgaacaact tttacttggg gagtaccagt caagagtgat ccgaaacatg tggtgtatgt
     9661 atggatcgat gcattatcca attatattac tgcactagga tatggctccg aagatgaaag
     9721 tctattcgaa aaatactggc ctgcagatgt tcagatggtc ggtaaagaaa tcgttcgctt
     9781 tcatacgatc tattggccaa tcatgctgat ggcccttgat ttgcctctac ctaaaaaagt
     9841 atttgggcat ggctggctat tgatgaaaga cggaaaaatg tctaaatcaa aaggaaatgt
     9901 cgtttatcct gaaatgcttg tggaacgtta tggtttagat gcactccgtt attatttgct
     9961 tcgtgctgtt ccgtttgggt cagatggtgt ctttacgcca gaagattttg tttcccgtgt
    10021 caattatgat ctggcaaatg atctagggaa cttattgaat cgaacgattg ctatgatcaa
    10081 caaatattgt gatggactcg ttcctgacta tgcctcactt gtcactccat ttgatagtga
    10141 actgtctacg acggctgcta acgttgtcgg acgttaccat gatgcaatgg aaaaaatgga
    10201 attcaataca gcattggctg aaatctgggt gctgatttct cgtgcaaaca aatacattga
    10261 tgaaacagaa ccatgggtat tagcaaaaga cgaagaaaag aaagctgaat tgaatagtgt
    10321 catgatccat ttagctgaat ctttgcgtat cgcagcgata ttacttcagc caatcatgac
    10381 agaaacgcca gagaagatct tcaatcaact aggattggac tctgaaacaa tgaatcttga
    10441 aggattacac tttggcgaat ttccttcagg aacaaaagta gttgcaaaag gtacaccaat
    10501 cttcccacgt ttagatatgg aagaagaagt tgcttttatt caagaaaaaa tgtctgaagg
    10561 tactcaaaca aacgaagata cagtcaaatg ggatccagaa gaaacagaac ttgtttcaac
    10621 gaaagaaaaa caaatcaaat ttgatgtatt tgaaaaagta gaactaaaag tagcagaagt
    10681 catcaactgt caaaaagtag aaggggcaga taagttgctg caattccgac tagatgctgg
    10741 agacagccaa gaccgtcaaa tcttgtcagg aatcgctgaa ttttatcctg atccaagcga
    10801 attgatcggg aaaaaagtcg tcattgtagc aaatctgaaa ccacgaaaga tgcgtggaca
    10861 aatcagtcaa ggaatgatcc tttctgcaga agcaccagat ggctctttac aagtaatcga
    10921 agcaccaaaa tccatgccaa atggctcaga aatcgcatag aaattcaaag ggggtatgac
    10981 actagttgtg tcataccccc tttttccgaa atttgagaag caattttcgt aaattccttc
    11041 ttattacttg aagccaatca tataatacag aaacagagaa ctatccaaaa taaatcctag
    11101 aaaaagaagt acgagcttcg ctgatttttg ttaatttaga ataatactaa taggaatcgt
    11161 aaaaacagaa aaaaagcata atgataaagg gtcgggcaga ttttaattga ttcatctggt
    11221 actctttttt attgtcctta cattcataaa gtttgaatgc aatgacttta ttacatctat
    11281 atttatatct aacagtagcg ttgatgtgtt aattataagt tctatcactt tatgttcaat
    11341 tagtttgtgc tcttatatgt gtgattgaaa atatagataa aaaaacaatc atcggctttg
    11401 acttcgatga ttgttttctt tattttgtaa aaatcctatc acttgatttt atggtaacct
    11461 tttatttttg tcttcaaacg gcttggtaag agagcagtaa gcagtgcaaa tgggatcgaa
    11521 aagacatacc agaaaatcgt acgtccgata ccataatgtt gatagagctt tgtcaacatc
    11581 acgtgtaaca agatcaaccc taaaagcaag gagccagcta taaaccaatg attatcccaa
    11641 tgcatgactt cactaagtgc catcactcca aaaggataga aataaaaata gatcccgact
    11701 aaggtcatcc gccagttctt tgtaaatgtt ccgatattca ataaaaagaa aatcgctgaa
    11761 agcaaaatac cgataggcgg aaaaagccca accaaaaagg aatacaacat cccccacaag
    11821 atcatcacag gacctttgat caatgcaacg attgcgatga acaaagtcag caatattagt
    11881 ttttgtgata acgttgcaac agtcattaat ccaaataaaa ttaatgtgaa ccaatgccaa
    11941 tgggactgct gttgttcttt acgggaaaaa tcgacccggt tggataaata atctgctaat
    12001 ttcggataag aacgcttaaa atccataaac tgttcctcct tcgtggaaaa ggtaggttta
    12061 gtatacgaaa aataaaaaag aaatacatcc gtcttaagag ggagtttttc actgaaagtg
    12121 gagaaaaaag aatggtaaat taaaatattc tcagttatac tgaaaattat accaaatttc
    12181 aaagaagaaa gaggatggga atgaaaggca aactaaaacg agaaatcaat ctgtttggcg
    12241 cattagctac cgttatggga accgtgatcg gtgcaggcgt cttcttcaaa actgctgctg
    12301 ttactgctag tactcagtct acaagtttga cattgctagc ttggcttttg ggtggtttct
    12361 taacgatctg tgctggattg acagtggctg aattagctac agcaatcccg gaaactggtg
    12421 gagctgtaaa atatattgaa gctgcgtatg gaaaattgcc cagcttttta ttaggatggg
    12481 cgcaaagctt gatttacttt cctgctaata ttgctgcatt atcgattatc tttgcgacac
    12541 aattgacgaa cttattacaa ttatctaccg attatctttt gttgattgca gtgatcaccg
    12601 ctgtttctgt gacagggttg aatttgttag ggacaaaagt cggtgcttct gtacaatcag
    12661 tgacgttgat tgttaaatta ataccaattg ctgtgattgt catatgggga ttattgaccc
    12721 caggacaagg aactgtccag ttatttccaa tcgaagctgg aaaagatgtt acttttgtcg
    12781 aaggattgag cagtgcgttg ttagcaacgt tgtttgctta tgacggctgg ttaggtgtcg
    12841 gtgcaatggc aggggaaatg aaacggccgg aaaaagattt gcctaaagca attattcttg
    12901 gtttgagttt tgtaacagtc gtttatctat tgatcaattt tgtttttttg aaaactttgc
    12961 cgattgatca tcttgccggt aatttgaatg cagcttctga agcatcagac gtcatttttg
    13021 gaggaatcgg tggaaagctg gtcactattg ggatcttgat ctcggtatac ggtgcattga
    13081 acggttatac actaactggg atccgcgtgc cttatgcgat ggctttagaa gacgagctac
    13141 ctttcagtaa acagctgaca aagctttcaa agaagtttac ggttccttat gttcctgcgg
    13201 ttttccagtt agcagtagct tgtattatga tgagccttgg ttctttcgac tttttaacag
    13261 acatgttgat ttttgtgatg tggctattca gtttactgat ttttatcggt gtctttattt
    13321 taagaaaaaa agcgccggaa ttgccacgtc catataaagt accactttat ccaatcgttc
    13381 cgattattgc gattctcggt gctattttca ttttaggtat gacgatgatg acgcaaacga
    13441 aattagcatt gatcggtata ggtgttacct tgataggtat cccagtctat tatcaaaaaa
    13501 agaaaaaacg ctcagaagag taaaatattt caacaacaga cagaaaaagt acgaactagg
    13561 tcctctagat cttcgtgctt tttctatttc aataaaacaa gttcttctat tttgattttt
    13621 gctacttctg caagtagtgc ttatgtgcta aagtaagaat gaaaaggaga gataaacatg
    13681 atatttgatt ctcataccca tttaaatgct gaacagttca atgaagatat tccagaaacg
    13741 attcagcgag cacaagaaat gggggtaacg aaaatggcgg tcgtgggctt cgatacgcca
    13801 acgattgaaa agtctttgca attaagccat gactatccaa atatatacag tattatcggc
    13861 tggcatccga cagaggctgg cagttatacg aaagaaatcg aaaataaatt acaagaacaa
    13921 ttgactttac caaaggttgt agcattaggg gaaattggct tggattatca ttggatggaa
    13981 gacccgaaag aagtccaaga taaagtattt cgcagacaga ttgctatcgc aaaagaaatg
    14041 aacctaccaa tcagtattca tactagagaa gcacttgaag acacgtatca aatcctaaaa
    14101 gaagaagatg ttcgagatat cggtggaatc atgcatagtt tcagtggtga ttatgaatgg
    14161 gcaaaacgat ttcttgactt agggatgcat atttcattta gcggtgtcgt cactttcaaa
    14221 aaagcattag acgtccaaga ggctgcagca aatgtaccaa tcgaacgatt acttgtggaa
    14281 acagatgccc cttatctggc accagttcct tttagaggaa agcgaaatga accaggctat
    14341 actcgttata cagtagaaaa gattgctgaa cttcggaatc ttccgacaga agaagtggct
    14401 gcccaaacat ggacaaatgc gcaccgatta tttggtctaa gcgaacatgg ataagatgaa
    14461 gatccaagag attatagtcg ttgaaggaaa agacgataca agaaggctgc gggaagtagt
    14521 tgatgcagat acgatagaaa caatagggtc tgcaatcaat gaagagatcc tgatgcaaat
    14581 tgaacatgcc caagagactc gtggagtgat cgtttttacc gatcctgatt tttcaggaga
    14641 aaaaataaga aaaatcatta tggaagctgt tcctcaggca aaacatgctt ttttgccgcg
    14701 cacacaagct aaaccaaaga aaaagggaag ccttggtgtc gagcatgcaa gtgatgctgc
    14761 tattttagaa gcattgaaaa aggtcgtgac gccagacatt tcccaaacgg ctgtttctga
    14821 aatcactaga caagaccttt tagactatgg tttaatagct ggggcacaag caaaagaaaa
    14881 acgagaaaaa ctaggtgacg agttgcgcat cggttacacg aacggcaaac aattggaaaa
    14941 acgtttgaag atgtttcgta ttacgccgaa agaactcgcc caagcaatga aaatagtgga
    15001 ggaacaacat gagtgaatat cgtgaaattg cgacaccctc tagaacaaaa gagattttat
    15061 tgaaacatgg tttttcattt aaaaaaagtt taggacaaaa ttttctgact gaaccaaata
    15121 ttttaaggaa aatcgtagaa actgcgcaaa tagatgaaca tacgaacgtg atcgaagttg
    15181 gaccaggaat cggtgcattg acggaacaat tagccaagca tgcaaaacaa gtcgtagcat
    15241 ttgagatcga tgatcgtttg atccctgtat tggctgatac gatgcaaccc tatgacaatg
    15301 tgactattgt acatcaagat attttaaaga ccgatttgtc aacagctgtt agagaaacat
    15361 ttcatgagga gcttccgtta aaagtcgtag cgaatttacc ttactatatt acgacaccga
    15421 tcatgatgca ttttcttgaa tcagatttgg ttgtggatga actagtcgtc atgatgcaaa
    15481 aagaagtagc tgatcgtatc tctgctgaac caggaacgaa agcttatggt tcattatcga
    15541 ttgctgttca atattatatg gaagccagtt tagcattcat cgtaccaaaa acagtatttg
    15601 tccctcagcc aaatgtagat tcagcgattt tgaaactgac aagaagagat ataccggcag
    15661 tcgaagtgac agacgaaaaa gcatttttcc gattgacaaa agcggcattt cagcaaagaa
    15721 gaaaaacgct ttggaataac ttgcagcatt cgtatggcaa agatgaccag acaaaagcat
    15781 ggttagcaaa aagcttggaa acagctggaa tcgatccaaa acgtcgtggg gagactttgt
    15841 cattacaaga attcgccgca ttaagcaatg cgatgtcaga aaatatgcag taaaaaaaga
    15901 ggttgtgaca gaagttgtga aaaagctgtc ctgcatcaag taataagaac agccaaacaa
    15961 aaatagttcc tcatgttttt cgtttgtttg ggcttattac cgcagatgca agcttttgaa
    16021 caccgtttaa gaaagaggtt gtgggcctgc cgtttaactc taagtcacaa ggaacaattt
    16081 caaaaaacag cttctcatgt ttttgagtta gttggtctta ttacttgatg caagcttttg
    16141 accactatta tgccgaacaa ggagatgtga cacaaatttt gtcacatctc ctatttttgt
    16201 ttcttgatca aaaaattctt atacttgata ctcacactca ttttgtatgg atttagaaaa
    16261 gaatatgtgt cttgacagtt attagtaagt gagttatact aagtcgacat ttatgtgtca
    16321 agacatatta ggagagagaa aaaatgagaa aaaattcagt tcgaaaacta acgatttctg
    16381 ctttattgat tgggatgggg gtcattatcc caatggtcat gcctaaaatc atgattccac
    16441 cagcttcctt tactttggcg tctcatgtgc cattatttat tgcgatgttt tttacaccag
    16501 gagttgcagt ggctgttgcg ctaggtacga catttggttt ctttttaaca acgccggtta
    16561 tcatcgcatt gcgagcattg tcacatcttg tgtttgcgtt gattggggct tggtacttgc
    16621 aaaagcatcc gagtatcgtt ttaaaaaatg gacagtttac ttttgctaat tggcgtttcc
    16681 aagggttcaa ttttgtgatc ggtgtgattc attctttagc agaaatgcta gtagtcagca
    16741 tcttttactt tattggtaat atgcctgaaa catattattc tcaaggatat ttttatacag
    16801 tattcatctt gatggggatt ggtgggctta tccacagttt agttgattat aatattgctt
    16861 attttatagc aggaacactc agcaaatatt ttgatatccc cgtatttacg gcagcaaaaa
    16921 aagaaaatcg gaaagagtcg attcaagggt acgcgaagaa aacgacatat tagacatgat
    16981 ctctcaaaaa aaaaactctc atctagtaat ggataataaa tcctctaaga tgagagtttt
    17041 ttgtcctaaa aagagctgca ccaacatctt ctggcacagc tctaacaggg ggcaatttat
    17101 ggaagtttga tgacttgttc tgtttcttta tcaaagaagt ggcctttgct gatgttgaag
    17161 gcaaggtcga ctatttcgcc tggtttatgg aaatctcttg catctacttt tgagatgaac
    17221 tcagtagaac cagtttttgt gtaaagcatc gtttcagctc caagtaattc ggaaacgaca
    17281 acttctgatt tcactacggc ttcaggtgaa gcttcaaggg ctacttgttc actgtggatg
    17341 tcttctggac gaataccgaa gataacttct tttccttcat aacctttttc aactaatact
    17401 ttgttttttc cttcaggaat acgaagctta agcccatgtc catctgtgat aacaccattt
    17461 ttcaatgtca cattaaagaa gttcatggca ggagatccaa taaagccggc aacgaacata
    17521 ttgacgggtg tatcataaac ttctttcggt gtaccgattt gttggataaa tccgtctttc
    17581 atgataacga ttcggtcagc catagtcatt gcttctgtct gatcgtgagt aacatagatg
    17641 gtcgttgttt caagacgctg gtgaagtttg gcaatctcag cacgcatggc tacacgtaat
    17701 ttagcatcta aatttgataa tggctcatcc attaagaaga cttttgcatc ccgaacgatt
    17761 gcccgtccca atgccacacg ttggcgttgt ccaccagata aagcagctgg ttttcgtttc
    17821 aagtattctg tcagacctaa gatctctgct gcattgtcca cacgtttttt gatgtctgct
    17881 ttatcatatt tacgtaattt caagccaaaa gccatattat caaaaacagt catatgagga
    17941 tacaatgcgt agttttggaa aaccatggca atatcacggt ctttaggtgc cacgtcattc
    18001 atgacttttc cgccgatatt tagttctcct tcagagatat cttccagtcc cgcgatcatt
    18061 cgcaaagtag ttgactttcc acaaccggaa ggaccaacaa aaacgataaa ttcacggtct
    18121 ttgattgata gattaaaatc agttacagaa taattttctg cattgtcata ttttttatat
    18181 acgtttttca gagccatttc taccataata cgttccacac tttctttttt agttttatta
    18241 actatttaaa gtataaatga aagcgttaac taacttcaat gtcatgttga acaagaattt
    18301 tttctttttt ttgtcaatgt gctagtttta agctttaata aatatccata agaaataaaa
    18361 actgatacac tggagtaaat aagtatgtta acaatatcaa aaggagtgtc tcttatgaaa
    18421 atcgctttga tcgctcatga ccgaaaaaaa cctatgatgg tgaaattagc aacagcgtat
    18481 aaaacaatat tggaaaaaca tgaacttttt gctaccggga cgactgggca gaggatcacg
    18541 gaagcaaccg gcttgccgat ccatcggttt aaatccggac cgttaggcgg ggatcagcaa
    18601 attggagcca tgatttcgga ggatcagtta gatttggtga tttttcttcg agacccgctg
    18661 gctgcacagc cccatgaacc agatgtaaca gcacttatcc gtttatctga tgtctatgag
    18721 attccgttag ctacgaatat cggaacagct gaggtgctac taagaggact ggaagccggc
    18781 ttcctagatt ttcgaagaat cgtccatgaa atagacaagc atccactttc attttgatgg
    18841 ataagcgtat ggaaaaataa cgtttaatgt tcgcctatat gtagctataa aagctaaaca
    18901 aactgataat atgcgatata atacgaacgt attggataat ataaacaata atattagttt
    18961 ttcgtatttg cagtaaatgt gaaaatatgc tatagtttct gtgggaaaag atcccaaaaa
    19021 taatacagag tagaaaataa agcgttaagt gctaagagga tgggatgttg cctcttggac
    19081 gaaggacgta atgttcgcgg ttttattttc gcattcgctg catgatacga tgtagcagct
    19141 cttaaaggag atgctaaaaa tgaagaaaca ccggttagac gcacgtatga ttgctattat
    19201 gggcttattg attgcattga tggtcacttt gtcccgactg gtagcaatcg agaccccatt
    19261 tattaaaatc agtgtcacat ttattccaca agtgatcatg ggcattcttt ttggtccttt
    19321 ttggtcaggg ataggcgcag ttttagctga tttagtagga atggccctct tctcgaaatc
    19381 tgcattcttt attggattta cattgaatgc atttattgaa ggagcaatct acggattctt
    19441 tttctatcga aaagagatca cttggaaaaa tgccattctg gctacgctta gtgtcacgct
    19501 gatcatcaac ttatttttga caccattatg gcttgcgttg atgtaccatg tgccattgtt
    19561 cagctgggtc gtttgggcgc cccgcctgtt aaaaacagta atatggttac cgattcaatc
    19621 aattgccatt tattacgtag gacgtagtat tccttacaaa aaaattttaa gaagtttagc
    19681 gatccacgct aaataaaaaa caagcagtct tcccatccca gaagactgct tgtttttatt
    19741 gtgctgtgaa ttgtgcttga tagagccgtc ggtaataacc atctttttga agcagctcat
    19801 catgggtgcc catttcgaca atagctccct gatccatcac taatatctgg tccgcatttt
    19861 tgattgtgga caggcgatgg gcaatcacaa aactggtttt tccttccatc attgctaaga
    19921 aggcttgttg gatttttttc tctgtcaatg tatcgactga gctggtagct tcatctaaga
    19981 tcaacatagg gggattactg atcatcgttc gagcaatcgt caacagttgg cgttgtccat
    20041 ctgatatctt taacccttga ccgccaatct tagtatctaa tttttccggc aaacgttcta
    20101 caaattcata catataagag gcttttaggg catcattgat ttctgcgtca cttgcttccg
    20161 gattcccaaa acgaagattt tctcgcaatg tactgtcaaa tagccaagta tcttgtaaca
    20221 ccattccaaa acttttacgt aatgtatcac gttggataga gcggatgtca tggtcatcga
    20281 ctgtaattgt tccttttgtt gtgtcataaa aacgcatcag caaattaaca agtgtggatt
    20341 ttccggcccc tgtttttcct actatagcaa tggtttgacc tggataagca gtaaaattga
    20401 aatcttcgat caaacgctgc ttggggtcat aagaaaaaga aacatgatca aaagagactt
    20461 ttcctttgat atttttgggt tccaaggcat aggcatctgg caaatcaggc ttttcttctg
    20521 gctgatcgat caaatcaaat gctcgttcta gaccagaaaa agcggtttgc agttgtgtcg
    20581 tgattccaga aagttcgata aatggtttag aaaactgact tgagtagatc gtaaagctgg
    20641 aaatcacacc aacagtgatt gacgaaccac tcttcaatgc caataggccg ccaactaaac
    20701 caatcgataa ataagcaagg tgatctacaa aacgagaaga cgggtttgtc aaggaagaag
    20761 aaaattgtgc ccgttgtcct ttttcatata gatcagcatt tagcagttca aattgctgtt
    20821 gactagcttc ttcttgctga aaagctttca cgattttctg gttaccgatt cgttcggtca
    20881 caaagcccga gatatcccca ataatccttt gctgtctatc gaaatttgtt tgtgaagcac
    20941 gagcaacgat ccaactcaca aggaaaataa ttggtgtaga acaaagaacg accaatgtca
    21001 gaagtggact tagacgcatc ataaaaataa acgaaagaat gatgattgcc actccagaaa
    21061 ataattgatt gaaggccgca gaaattgcaa tggaaatatt gtccatatca tttgtaaatc
    21121 gactgacgat atttccgtgg gagttttgat cataataacg aagtggcaat cgattcagat
    21181 gagcaaatgc atcttttctt aattttgcaa cggataagta agctaaccga ttgcttaaca
    21241 cttggatgag ccattgactg actacgttga ttaaaacgat accaccgaat agaataagta
    21301 aatggaacag tcgattgaag cggacctgtc cttctccaat catttgatcg atactttgac
    21361 caatttgtaa cgtcatcaca actgttgcaa tcccattgat gattcctagt atcacagcta
    21421 gccaaatgtc ttttgcatag gcagtaaggt aaggaatgaa tcggcggagc gtctgcaagg
    21481 ataatttttt tactttcata actattcttc ctcctgtgat gcgacgattt cctgatattc
    21541 tgctgattga gcaagtaatt cttcatgggt accctgagca gcaatcttac cttgatccat
    21601 cactaagata tgatgtgctt cttgaataga gcggacacgt tgggagataa taatcactgt
    21661 actgccaaga taagtctgta gcgccttacg caaatccaag tctgtttgat aatccaacgc
    21721 acttaaagag tcatctaaaa tcagtaatgc tggcttggca atcaaagctc ttgcaatcgt
    21781 cagtcgctgt ttttgtccgc cagagaaatt tttcccattt tccatgactt ttgtatctaa
    21841 accatttgga agctgacgga caaattcttc tgcctgagcg attttcagag cttcccaaca
    21901 ttctttttct gtggcgtctt tcttacccca ttgaaggttt tcacgaatag tcccggtaaa
    21961 tagtacagaa gtttggggaa caagagcaat ttgctgacgg agatgatcca gctgccaaga
    22021 acgaacatcc attccgtcca ttataactgt accggaactg acatcataga aacgcggaat
    22081 caattgtgtc aaagtcgttt tcccgcttcc ggttggacca atgattccaa ggactgtatt
    22141 tcgcttcagc tgaaatgtaa tattttggag agaaagacca gaatcaggag tataacggaa
    22201 gtcaacatgg tcaaaagcga taattgcttc agaagaaaaa tcgggagtag tactgacctc
    22261 agcttcaaga atcgaatttt ctgtgtctag cacctctttc acccgatttc ctgaagcttc
    22321 ggcacgtgtg aagatcacga cgaggtttga aacaacgatc agtgccaaaa gcatttgatt
    22381 catataattg atcaaagcaa gaacttgtcc ttgttgcaag ctaccaatat ttactttgat
    22441 cccgccaact gtcagcaaac agatgatccc gacattcatg atcaaggttg tagcaggtga
    22501 taatagggca gagatattgg aaacacgtaa ataattgttc gctagatcat ttgtgctttt
    22561 atcgaacttc tctgtttctt tttttgtctg cgcaaatgcg cggatgacac gaacaccgct
    22621 aagattctga ctaacgtgtt cattgagctg atctagtttt tcttgcactt tttggtagag
    22681 aggaacggtt tttttgatga taaaaaataa aatgattgag aaaataggca ataatgctaa
    22741 gaaaaacaga cctacttccc agtcgatcac aaaagccatg accactgacc cgatacttaa
    22801 aaacggtgct ctgatcaata aacgaatgac cattgctaaa gctagctgaa gctgattgat
    22861 gtcgtttgtc attcgggtga tcaaggtatc tgttccaaaa tgattcaact cgttgtgaga
    22921 gaaagtattg atttttttga ttagctgatt acgtaactct gtaccaaatc cttgtgaagc
    22981 tactgaagca tagtattggc aaatgatagc acaaatcaga ccaatcacag acatagcgac
    23041 catccataag cccatttcaa tgatttttcc tcggtcattc atttttagtc cattatcgat
    23101 caaggaagcc atcattaaag gcaggacaag ttcgaagaca gcttcaagaa atttgaagaa
    23161 cgggcccaaa atgatttgct tacgatagtc ttttgcataa cgtaataact gaatcatatg
    23221 attcctccta ttatttattt gtccacaatt gaaaaaacaa gtactaccac attgtagctt
    23281 aggaaattta gaatgaaaag agaacaagcc ttttcataaa tgaaagtttt attatgaaga
    23341 agctttagaa attgaataga ctattttttt taaaaaaaag aaaatgagaa aacatgccag
    23401 tctcttcatt cataggaacg tctattttac ttaatttttc tataaatgaa ttctgcataa
    23461 aaaatatatc aagtaaatgt ttatagatga aactctattt acttcttttt taatttgttc
    23521 ttgcaatctt ttttgctacg taatttttgt aaaaaagtgg gttgagagaa atctaattga
    23581 ttttcaaaga aggagtatga aaatgagaaa aatatttatt cgtttattgt gggtactatc
    23641 ttagaggaat aaataatagt ggagaaaact atggtttggc gcagattcta tcaggtttga
    23701 tggaacgaag acaacctccc gacatcaagt caaaagccac ttgagatttt gatctgaaaa
    23761 taaaaaaaga aaacaaggta ggaacatcaa tgtttctacc ttgttttcgt aatcaatggg
    23821 aaaaaactaa gagtggtgta cgtaatcaat aaaaaggatg gtgacaacag tacctcttta
    23881 ctctctgaaa gcatcataac tcgtttttcc tcattatgcc aataaattgt tgttatacca
    23941 catataagga tttgtaatag ctaaaaacag acaggaaagt tgaaatctgt gaatcttatt
    24001 ttgtatggaa ggatttatag aacgcaaaaa tcaagataaa gatgaataaa aatcctgttt
    24061 cggctatata ttgcgtatct acgccaataa aacgagtttg ttctgtcata gccatataaa
    24121 gcaaaggcaa aaatacaact acagcgagat aagatccgat gatttctcga aaagttttcc
    24181 aggaagtatg tttcctgttt ttatatttat ccgatttcat tgaatagtca tagcctcctt
    24241 attctttcat atgttgaaat tccagtataa aaactggaag gaactgtacg ttttttagaa
    24301 taaaaattat aagggataag taggctgctg tctataataa gatatatttt tcaattcttt
    24361 attaaagatt ttattgacaa aatgaatccg ttttctatga tggaggaggg gtgaataagt
    24421 tgttgaagaa ggaaatttta tgttacttag agaaccagac agcctttttc gatttagaac
    24481 atatgaacga ggtctttaca gcacaaaggt tagctgatca ttttggggta aaaagaaaca
    24541 cagtcagtca ttatttgaac cagttaaatg atgagcaact actagtcaaa atcaattctc
    24601 gaccagtgat ttatttccac aaagaagctt ttgaaaaaca attttttaag ttacgcacga
    24661 atttttattt ttctatcgat gatctcaaag aggaacagcc ttttttcgcg caaccaaaag
    24721 acttattctc ttttatgatc ggatacgacg ccagtttgaa agaaagtatc gaacaaatca
    24781 aaacagctct ttactatcca gatggcggat taccactttt gattacaggc gaaagtggca
    24841 caggtaaaag ttatttagtt aatttggtct atcagtattg tctgcttcat gatctgctag
    24901 aagattctgc accattcatc acttttaatt gtgcacaata tgcagataat cctgaacttt
    24961 tgactagcaa tttgtttgga catgttaagg gagcgtacac tggtgcagaa gaaaataaaa
    25021 aaggggcttt tgaagcagca gatggtggga tcttgttttt agacgaggta catcgcttaa
    25081 caccagaagg tcaggaaaaa ctgttcacct atcttgatca aggtgtgatt tatcgtatgg
    25141 gagaacctaa tttgtcacgc cggatcaaaa cacgtctctt ttttgctacg actgaagaga
    25201 ttactagtca tttcttaaca actttcattc gaagaatacc tatccgaatc gaactacctg
    25261 cacttaatca gcgtagtcgt aatgaacggc tagaactgat ttactctttt tttctcgaag
    25321 aacaaagaaa aatggggagc cctttgtcag tcagtggacc agctttgtca cttttaacaa
    25381 gtcagaaatt atccggaaac ataggagagc tgaaaaatat cgtcaaagtt tcagcagcaa
    25441 aagcatatgc tgaacagcgt gaacagcctg aaatccatgt cacgatccat catttgcaaa
    25501 aagaactact tgcgcagcct attactaaaa atacagcaca gcaaggaatc tatattacgc
    25561 aagaccagac cttagagcaa ttaatggaga agcaacagcc cgaacagcag cgaatcgtta
    25621 aaagttttga gcaaatccta attgatttca agaaaaataa ctgtctgcta tattcttgcg
    25681 aaggaaaatt aaagcaagaa gtgattcaat tatttgattt tttgctgttt gagaccagta
    25741 gacaagaaaa acacgagctg ctggtttatt ggacacaatc tatccgagag acctttcgac
    25801 aaatggaaac tgcctatcaa atcaaattcg atggaaacag tgtctatgcc ttgagttact
    25861 atctctatca gcgaagcact atcaaatggt taccggaaga acatgatatt atccaactaa
    25921 tcaaagaatt agaacaacaa gtttctcagt cttatccatc tagttatcac tatgtccaac
    25981 gaattctgga attaagtaag atcaaattag atattgaaga cacaagtatg gatcggattt
    26041 tactgacgat ctatctaaaa aaagcgaaat ggtcaaaaga aaaacgactg ccaaaagcga
    26101 tgattgctgc tcacggttat gcaactgcta gcagtatggc aaatgtagta aatcgtttat
    26161 tacaagagga tctatttgaa tcatttgata tgccactaga tgtcacacca cagcagattg
    26221 cttcagaaat ccttgattat tgcgaaaaca gcgatgtttc aaatggattg atcatattag
    26281 tagacatggg atctctgaaa gaaatccatc agttttttaa aaaacagtta tccgtaccgc
    26341 ttttgatttt gaataatgtg acgacacctt tagcaatcac agtaggggaa tgcctgcaaa
    26401 aaaatgtatc attagaagag atagcagaag agactgttcg acagatccag ccagaatggc
    26461 gactgctcta tccagaggaa aacaaaccca aagcactcat tactacttgc ttcactggaa
    26521 tcggtacggc ggtccactta agtgaactgc tagaaaaaag cttacctacg gcttgtcagt
    26581 tgaaaatcat cccatatgaa tatcagcaat taaaagataa gaaaaacagt gacccattat
    26641 tttccatata cgaagtcgta ggaatgattg gcaccacaga tcctgatatc accaatatcg
    26701 actatctttc attagaagac ctcatctcgg gggaaaagat gtctgtacta gctgaatggt
    26761 tggacactac tatgaatgct tcagagaagg aaatattcaa tcagcgcatc attcgtaatt
    26821 tttcattgga aaaagtactg gattccgtga ctattctaga tacagagaag gtgatgggag
    26881 aaatcgatca ttttatgaga gaattagagg tgcagttgaa tcgaagcatc agcaatccca
    26941 aaaaattagc gttgtatgtc catgtgagct gtctcattga acgattgatc cgacaaatgc
    27001 caatcgaaac ctatcaagga ttagagaaat ggaagcagtg tcaaaaagaa gggttatctg
    27061 ctattaaatc tgcgtttagt gtcattgaag agcattatag tgtcatgatc cccaattctg
    27121 agattgccta tatctatgat attttgagtg aagatacaga gtttctctcg atagaagaag
    27181 aattttgaac ataagcaagt tgttgccact aattttggca tgcaacttgc ttttttagta
    27241 tgtgtaagtg aaaagaggag atgaaaaagt ggatagagaa attatcttag cttcccatgg
    27301 aaaatttgct tcagggatat tagattcatt agagctgatc tatgggaaaa atcattctat
    27361 tactgtattc gattgctata ctgatgagaa ttttgattta gcggaaacag taaggcagct
    27421 ttttatgagg tacaaagata aagaaatcat tgttctgacg gatctttttg gcggaagtgt
    27481 caacaacgaa ttcttacaat atatcaatcg ggatcatgtc tatctcgttg ccggattgaa
    27541 tttgccacta ttgattgagc tagtatctcg gttggacgct gaagtagaga caactgtttt
    27601 gatccagcag gtgctaactg attcaaaaaa aatgatccag ttttgtaacg agcggctcaa
    27661 tcagaaaata gaagaagacg aattttagga ggaagaaaaa tgattgtatt gacaagagtc
    27721 gaccatcggt tattacacgg acaagtagct ttttcatgga cacaaacaat aggcgcagac
    27781 tgtattttga ttgctaatga tgatgtacct acgaatgaga tacgaaagac aacgatcaaa
    27841 ttagccaagc cacaaggagt caaactagtg atcaaatcaa ttgatgactc gattgccgcg
    27901 ttgaaaagcg gggtgacaga taaatataag ttattcatcg tagtggaatc gatcgaggat
    27961 gcatataagc tggcagaagc gtatccagaa atcaaaacca tcaacttagg agggatcaag
    28021 gcaaaacctg gtactcgcag catcggaaaa gcggtaaata ttttaccaga agaggaggaa
    28081 cgcttgaaac gattaattga caaacaaata gaagtagaaa tccgtcaagt accagcagat
    28141 aaaaaagtgg atgtaagaga agttttgtaa gaaaggaaga acctcaatga ttgtacaagc
    28201 agtcttatta ggaattgttg catttgtcgc acaatcagaa tatgcactag ggacatcgtt
    28261 gctttctcgt ccgattgtga cggggctgtt tacaggaatc gtgttaggtg atgtaaaaac
    28321 tgggatcatt atgggcgcaa ctttagagtt agcatttatc ggatcgttct cagtaggtgc
    28381 ttcgattcca cctgatgttg tgaccggtgg gattttaggg acggcttttg ctattacagc
    28441 tggagccggt acagaaaccg cgcttttact aggtttgccg attgctacgt tgacattgat
    28501 attgaaaaat atttacttag ggcttttgat tccaattatg aaccataaag cagacaatta
    28561 tgcagaagaa ggaaattata aaggagtcga gcatatgcac ttgcttgccg gtatcggtct
    28621 ttccttgatg cttggtgttg tggtaatggt ttcttatatg gtgggaagca atacgatcgg
    28681 aaatctatta aatatgattc ctgacttcgt tcaaaagggg ttgtcagtag ctacagggtt
    28741 gattccagct cttggttttg cgatgcttgc tcgtttgctg atcaacaaac aagttgcacc
    28801 atattttttc ttaggttttg ctatagcttc ttacttagag attcctgtga ccggagtagc
    28861 tatttttggt gcgattttag cagttgtggt agtcaatatt atgaatgtcc gtcaactacc
    28921 acttcaaaca actgcagggg aggtagaaga agatgaagaa ttctgagatc aaaaacagca
    28981 aaataacgaa aaaagagcta aatcacgtat tttggcgttc ttttcaaatg gagttttctt
    29041 ggaattatga acgtcagatg aatatggctt atgtttatgc aatgattccg attttgaaaa
    29101 agttatatca gtcgaaagaa gaaatggcag cagctttgaa acggcatcta gagtttttta
    29161 acacgacccc acatatcgtt acactgattt taggaatcac ggctgcaatg gaggaagaaa
    29221 ataaggatga tcctgaattt gatgtgactg cgatcgatag tatcaaaaca tctttgatgg
    29281 gacctcttgc agggttagga gattctttct tttggggaac tttgcgattg attgccacag
    29341 gtgtgggtac ctctttagcc atgcaaggaa atattttagg ccctatcttg ttcattttga
    29401 ttttcaatat tccgcacatt ctgtttcgct atctagcaac aggttgggga tatcgcttag
    29461 gaacgggttt tttgaaaaag atccaggcaa acggtatgat ggaaagtttg acattaggcg
    29521 cgtctattat tggactgatg gtcgttggag caatgactgc cacgatgatc accatcaata
    29581 ttcctttaaa aatcggttca ggagaaaatg ctgtgactgt tcaaagtatt tttgatgata
    29641 tcgttccaaa tatcttatgt cttggagcat ttggcatagt gttttatcta ttgaagaaag
    29701 aagtgaaacc attaacgatc ttgatcggac tagctttctt tggaattttt ggttcgtgga
    29761 tagggatttt ttaaaaaagg agcagagaaa atgtttacga tgcaagatta tatctatgaa
    29821 gaaaaggaag tactaagtac gatcttgaaa aagaatgatt tttcgacaag agaacatatg
    29881 aaaaaaacag tgaatttact gatcttagca acgggttcat cttataacgc ttgtttagca
    29941 gcgaagccag cattggaatc ttatggtgat cttactgtcg atattcaaga acctttttat
    30001 tttttcaatt atggaaaact ttctccttca atcgatactg tgattgctgt gtcacaaagc
    30061 gggaaaagtg cttctactgt tgaagcagta aaaatgatac aaaaacaagg gttacctgtt
    30121 gttgctatca caaatgacgt gcaaagtcca cttgctttag aagctgcaca aattattgat
    30181 ttaggtgccg gggtagaatc agtaggcttc gttacaaaag gctattctgc gactgtttta
    30241 cagttactac tcttagggat aggaattgga ataagtaaaa ataaaatcag caaaaaaata
    30301 gaacaagact acatgcaaca gttgcgcaaa ataatcaacc atttaccagc gattattcaa
    30361 aaaacggaag aattttttga tggatatcaa agtttatttc gtttagcaca gcgtttcgtc
    30421 accattggat atggtccaaa ctggggaaca gctaaagaag cagagacgaa attgactgaa
    30481 acaatccgcg ttccgtcaca aggatttgag ttagaagctt atatgcacgg cccatacctg
    30541 gaggcagatg cttcgcattt gctattcttt attgaagggg aaagtgtaaa taaggaacgt
    30601 tcgcaaaagt tgcaaagata tatgagtcgg tacgttggag agactctcac cattaccaca
    30661 aaaaaagcaa gaaacgagaa aacacttgga ttagcaatag aatgtgatga atatctgtct
    30721 gtattagcgc ttgtcgttcc gtttcaacta ttcgcttata aaaccgcagt agctaaaggt
    30781 attgacttga acaaaaagat ttttgaagac tttgatacag tcttgaaaag taaattataa
    30841 gaggtggaaa tcatgctgaa attcaatgaa gaagaacaaa tcaaagcaat aaaaggcgca
    30901 ctagctttac gtccgcaagt agaagaaatc atcgataaac tttatgcgga aaaatttgac
    30961 gctgtctatt atctaggaat cggtggaacg tatgcttcct cgatgcaagc tgtcacttat
    31021 atgaatggga aaagcaactt gcctgtcttt gtacagcatg ctgcagaata ttacactact
    31081 ggaaacaaaa gattaacaaa agattctatc gttattttgt cctctgttac cggtacaact
    31141 caagaagtag tgaaagcagt agaacaaatc aagaaagtag gagcgacact gattggattt
    31201 atcgataaag cgaacagtaa gttgtctcag ctatgcgatt ttgtggtcac ttatccagct
    31261 cctggaacag aacaaatcaa attttttatg gcagcagatc gattgatgta tttgaatgga
    31321 gaattcgaag cttattcaga atactatgaa cagctcgaac gttatttacc aacagggtta
    31381 gtggaagcag agaaaaaagc agatgcattt ggcttatcat ttgcagaaaa acatcgacgt
    31441 gatagtatgc attattttat tggagcaggg aatcaatggg gagctgttta ttcatatgcc
    31501 atgtgttact gggaagaaca aagctggctt ccatcgaaat ctatccatgc tgccgagttt
    31561 cttcacggga cgttagagat cgtagaagaa acaaccccag tcacattatt tttaggcgaa
    31621 gatgaacaga gagtgttatc tgaacgtgtg gctaaacttt tgccaaaaat ttgcagcaat
    31681 tatacattga tagacacaaa agactatcca gtagaaggta tcagtgaaaa atatcgcgga
    31741 cgtgttttgt ctttcttatt gatgcatgta gtgacacaac gcatcgatgc tcatgtggag
    31801 cagttgaact gccatccatt agagatacgc cgctactatc gtcagtttga ttattaggat
    31861 agactggata aaaagaatat aaaaaataaa gagagcagcg ataactgctc cctttatttt
    31921 tttaaaatat tggcatcaat tacgttataa aacacatttt ttgcattatc tacagttcaa
    31981 cttataatct gtttaatggg acatgtgggt gccaaccatt ttttgttatg caatagtact
    32041 atttagttgt tgcatggatc cgtagtaaaa gtccaagtac aacgagttgc gccagtttac
    32101 atagcgtttt gtatccagaa tgttgactaa aacaaaagtt cctatgtcaa ccgtcaacag
    32161 agacaatctg tccgttgcag gacctgacag atttagaaat gttcaatctg tctcttatgt
    32221 attttaaatc aatactcact aggagaagtt tcctaacctc ctaatagtaa tgctggtagt
    32281 aacattgtca aaactgcttc ctcttaggaa caagcaaagc ataacgagtg taaaaataaa
    32341 atgtagacta ttgtaacata tcattgatta tttcaagtaa aaacgataaa agaagtaaac
    32401 aaacacttaa aaacaatgga aattagtccc aactttaaga aatgtatact ataatggaaa
    32461 ttatcaatta tttatttgga ggaatatcca tgaaacaaaa aatcgcagtt cttggtcctg
    32521 gatcttgggg cactgcttta gcacaaacat tggcagaaaa cgggcatgat gtccgtattt
    32581 ggggaaatgt acctgaacag attgatgaaa tcaataagta tcatacaaat cagcattttt
    32641 tacctgattt gacgatccca gaatcgatta tcggatataa agaattggca gaagcagtgg
    32701 ataacgcaga tgctatttta tttgttgttc caacaaaagc gattcgttca gtcgcacagg
    32761 aacttattgg taaaatgaat actaagccaa tcattataca tgcaagtaaa ggactagaac
    32821 aagatacgca taaacgaatc tcagaagttt tggctgaaga aattccagaa gaaaaaagac
    32881 aggcaattgt tgtattatct ggtcctagcc atgctgagga agtggcagta catgatatca
    32941 caacaattac agctgcaagt attgatcaaa aagcagcagc ctatgtacaa aaactgttca
    33001 tgaatgatta tttcaggatt tatacaaata atgatgtgat tggcgtagaa actggtgcag
    33061 cactgaaaaa tatcattgca attggtgccg gcgctatcca tggattagga ttcggagatg
    33121 atgcaaaagc agcaatcatg actcgaggat tggcagaaat cagccgtctt ggtgtcgcga
    33181 tgggtgccaa tcctctgaca tttatcggtt tgagtggtgt gggggacttg atcgttactt
    33241 gtacaagtgt tcattctcgc aattggcgtg ccggtaactt gttaggacag ggacataagc
    33301 tggaagaagt tctagaaaac atgggaatgg tcgttgaggg tgtggcaacg acaaaagcag
    33361 cagtagagct agctcaacag ctaggtgttg agatgccaat tactcaaaca atctataatg
    33421 ttttgtataa tggagaagat atcaaaaaag cagcaaaaga aatcatgtta cgtgacggaa
    33481 aaatggagaa tgaattttct cttcgttaaa tagatgatca atagttaatc gtcgtttagg
    33541 aggaacagca agtgaaggtc aaaaaagcag tcattcctgc cgctgggcta ggaacacgtt
    33601 ttttgccggc aacaaaagcc atggcaaaag aaatgcttcc aatcgtggat aaaccaacga
    33661 tccagtttat tgtggaagaa gcattggatt cgggaatcga agacatcttg atcgtaacgg
    33721 gaaaagaaaa aagacccatt gaagatcact ttgatgcaaa tatcgaattg gaaaacaatt
    33781 tgcgggaaaa ggaaaaaaca gaattactcg ctttagttga agaaacgact caagtcaatc
    33841 ttcacttcat ccgtcaatct catccaagag gactggggga tgccgtgctt caagcaaaag
    33901 catttatagg aaatgaaccg tttgtcgtca tgctggggga tgatttgatg aaagatgata
    33961 tcccattgac tcaacaattg atgatggatt atgaagaaac acaagcttcc gctgttgccg
    34021 tcatgcgtgt accagaaaat gaaacatcta aatacggaat tattgatcct aaaacagata
    34081 gcgaaaaggg tcgttgcaga gtaaaagggt ttgtagaaaa acctgaaatg ggaaaagcac
    34141 caagtaattt agccattatc ggacgttatc tactgactcc taaaatattt gagatattag
    34201 aaactcaaga accaggagca ggaaacgaga tacagctaac ggatgcactt cagactctta
    34261 accagacaga ggcggtctat gcgagagagt ttaaaggaaa aagatacgac gtaggcgata
    34321 agttaggata tatgaagaca aatattgaat atggacttca acattcggaa attgggactt
    34381 cattaagtgc atatattatc cagttgagta aaaagctaag aacagaaagt taactggaaa
    34441 taagtggcct gctgagaatg aaaggctatt tgttattaaa gcggcagctt gtgcgtcatt
    34501 tgcgcaactg tcgttttagt tttttgactc tagatcagtt gagtcgtgga aaacgaaaga
    34561 tagaaaaaga ctttcgtgaa tagattcaga aaatattatg ctaatggttt aatttttttt
    34621 taagttgtat aaaagaaaat gattacataa gagaaatgaa agccaagcca gaagattcat
    34681 agtagaataa aaaggcgaat tttttaatta taaaaaaagg tgtgtgttca ctatgggaaa
    34741 attagtcgct gttgcacagt cgctgcttga tatactcaag tggctgatgg aaggaagcaa
    34801 ttggatattt gtgttgccac tattgcttat tagtctattt atcatgtttc gcatggtcag
    34861 aaaaaaagaa acgtttctga tttttatctg gtatgcagca tccgttgggg ttgctacctt
    34921 gatggttgaa ttggcgttag gtagttggga agcttgcgta tttgctttat tttttgctgt
    34981 actgtatcta atcatttata tcccatatat gaaaagaaag tctcggatag gcagaaaagg
    35041 tagacataca actacttttt ctagtacaga ttctctcgaa caaagtagaa gaacgagaag
    35101 aagacggtaa tatttagtag gtatacgcaa aaaaagataa aataatggat aaactattga
    35161 gatgagagat ttatttaatt ggtggaaaaa agcttttttc acttatataa aagaatcttt
    35221 tttaaaggaa tgcttgttgt atcgggataa gccattcctt tttttatgtt atttatatat
    35281 atataaatca taccaatgtt tttttgtatt ttcttgcttg cacttggata agagattact
    35341 tacaataaat tcagatagaa acagctgaat aaaaaaaggc tccctgaccc ttagttggcg
    35401 ctaagaatca gggaatgacc agtcacacac atacaccctg accgatcatt ttgccatagt
    35461 caatgcagtg catcgaccta atttattgta cctaatctag ggtgaaaatt ctacccctat
    35521 gtagatattt tccatggtct gcacgttgtt ttatttgcta tgtcaaggta ttgggcgtat
    35581 tcgttcaatg ccttttttgt gtttgaaaca gcaaagacca catgtgttac tgtctaacta
    35641 ctgttttttt atgtacttcc ttagattagg cagctgtttc tattcatgtc aagtatagct
    35701 aggcgggaga gataaatgag tttatgttat tttgactatt atcaccaatt ggaagagaaa
    35761 ttaaggatag aagagccgct gatgcttcaa gctggcactt ggatcgcgaa acaaattaat
    35821 caaggtggta gattgcagat atatgctagc cgcacactaa gtggtgtagc atttgaattt
    35881 tgggatcaaa ccccggatct tgtaccaagt atattgattg aaaatccagc cggaggtgtc
    35941 tatgaaacgc tagaaggtgc aggacaggca attattgatc agctttctgt caaatcagaa
    36001 gacatttttc ttcttctttc gaatgaagga agaaacccgg caatcatcga actagctcag
    36061 tggatcaaag aaaatggtca tccattaatc attgttactg gatttgattt gtcacgaagt
    36121 atcaaatcgc aacatagcag tggtttgcga ttatttgaat ttgctgattt ggttttggac
    36181 aaccacgcca atttacatga tgcagtcttg actttgccaa atctagatcc agcgatctgc
    36241 ggaacagcct ctcttgcaac gatctttttg ctgcagcaag ttttgtattt tacagcaaaa
    36301 cagctagtcc aggacacaag tggaaaatag ttatccacat gttgacaaag ttccttaaaa
    36361 aaataatgtt ccacataaaa atggagcgtt tgaaaaaaag aaaacgatta ttaatgagga
    36421 ttaacaacga ctactttttt tgttttagtt attttaagat ggatcatctt tgattttaag
    36481 cttgttttgt ttaaagtttg ttatttttat aagttgtttc acagttatga gaaatgagtt
    36541 ataagaatat gtagtgtcag aaaaataaaa agtagtggaa aaagagacaa gaaagaatcc
    36601 atatggattc tttcttgtc
//
LOCUS       DAMEEU010000020        36570 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.021, whole genome shotgun sequence.
ACCESSION   DAMEEU010000020 DAMEEU010000000
VERSION     DAMEEU010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 36570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.021"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(27..1523)
                     /gene="lysS"
                     /locus_tag="PB779_001037"
     CDS             complement(27..1523)
                     /gene="lysS"
                     /locus_tag="PB779_001037"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HDE0738576.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="PB779_001038"
     CDS             complement(1634..2638)
                     /gene="dusB"
                     /locus_tag="PB779_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HDE0738577.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVDCREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="PB779_001039"
     CDS             complement(2639..3526)
                     /gene="hslO"
                     /locus_tag="PB779_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HDE0738578.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="PB779_001040"
     CDS             complement(3743..5854)
                     /gene="ftsH"
                     /locus_tag="PB779_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HDE0738579.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="PB779_001041"
     CDS             complement(5944..6489)
                     /gene="hpt"
                     /locus_tag="PB779_001041"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HDE0738580.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="PB779_001042"
     CDS             complement(6489..7934)
                     /gene="tilS"
                     /locus_tag="PB779_001042"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HDE0738581.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8054..8524)
                     /locus_tag="PB779_001043"
     CDS             complement(8054..8524)
                     /locus_tag="PB779_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HDE0738582.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8570..8995)
                     /locus_tag="PB779_001044"
     CDS             complement(8570..8995)
                     /locus_tag="PB779_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HDE0738583.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9062..9331)
                     /locus_tag="PB779_001045"
     CDS             complement(9062..9331)
                     /locus_tag="PB779_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HDE0738584.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9342..10937)
                     /locus_tag="PB779_001046"
     CDS             complement(9342..10937)
                     /locus_tag="PB779_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDE0738585.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="PB779_001047"
     CDS             complement(10952..14473)
                     /gene="mfd"
                     /locus_tag="PB779_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HDE0738586.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14490..15050)
                     /locus_tag="PB779_001048"
     CDS             complement(14490..15050)
                     /locus_tag="PB779_001048"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HDE0738587.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15403..16377
                     /locus_tag="PB779_001049"
     CDS             15403..16377
                     /locus_tag="PB779_001049"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HDE0738588.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16547..17947
                     /locus_tag="PB779_001050"
     CDS             16547..17947
                     /locus_tag="PB779_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HDE0738589.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18025..18747)
                     /locus_tag="PB779_001051"
     CDS             complement(18025..18747)
                     /locus_tag="PB779_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0738590.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18826..19332)
                     /locus_tag="PB779_001052"
     CDS             complement(18826..19332)
                     /locus_tag="PB779_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HDE0738591.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19455..21254
                     /locus_tag="PB779_001053"
     CDS             19455..21254
                     /locus_tag="PB779_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HDE0738592.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21322..22896)
                     /locus_tag="PB779_001054"
     CDS             complement(21322..22896)
                     /locus_tag="PB779_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDE0738593.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="PB779_001055"
     CDS             complement(23151..23660)
                     /gene="mreD"
                     /locus_tag="PB779_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HDE0738594.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="PB779_001056"
     CDS             complement(23664..24518)
                     /gene="mreC"
                     /locus_tag="PB779_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HDE0738595.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24673..25311)
                     /locus_tag="PB779_001057"
     CDS             complement(24673..25311)
                     /locus_tag="PB779_001057"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HDE0738596.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25312..25962)
                     /locus_tag="PB779_001058"
     CDS             complement(25312..25962)
                     /locus_tag="PB779_001058"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HDE0738597.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="PB779_001059"
     CDS             complement(25975..26874)
                     /gene="rsgA"
                     /locus_tag="PB779_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HDE0738598.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="PB779_001060"
     CDS             complement(27039..29108)
                     /gene="pknB"
                     /locus_tag="PB779_001060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HDE0738599.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29105..29845)
                     /locus_tag="PB779_001061"
     CDS             complement(29105..29845)
                     /locus_tag="PB779_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HDE0738600.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="PB779_001062"
     CDS             complement(29858..31216)
                     /gene="rsmB"
                     /locus_tag="PB779_001062"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HDE0738601.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31216..32154)
                     /locus_tag="PB779_001063"
     CDS             complement(31216..32154)
                     /locus_tag="PB779_001063"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HDE0738602.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32147..32638)
                     /gene="def"
                     /locus_tag="PB779_001064"
     CDS             complement(32147..32638)
                     /gene="def"
                     /locus_tag="PB779_001064"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDE0738603.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32653..35061)
                     /gene="priA"
                     /locus_tag="PB779_001065"
     CDS             complement(32653..35061)
                     /gene="priA"
                     /locus_tag="PB779_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HDE0738604.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35314..35619)
                     /locus_tag="PB779_001066"
     CDS             complement(35314..35619)
                     /locus_tag="PB779_001066"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDE0738605.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="PB779_001067"
     CDS             complement(35624..36238)
                     /gene="gmk"
                     /locus_tag="PB779_001067"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HDE0738606.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYINKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
BASE COUNT         9886 a         7989 c         6706 g        11989 t
ORIGIN      
        1 gaattcctta gacagctttt attcgattat ctcattgttg ggaatagcaa aacatcccga
       61 attgattgtg catcagttag caacattact aatctgtcga tcccgatgcc tagaccacca
      121 gttggcggca taccgtattc taaggcttcc aagaagtctt cgtctacacc gtgagcttcg
      181 tcatttccta gttcacgttc tttttcttgc gcttcgaatc tttctctttg atcaattgga
      241 tcgttcagtt ctgtaaaggc attagcaaat tcgcgcccca ctatgaatag ttcgaatcga
      301 tctgtgaatc gaggatcttc tggatttttc ttcgctaaag gcgaaacttc gactggatgt
      361 ccgtatacaa acgtcggttg tgtcaatgtt tcttcaacaa atgtttcaaa gaattcattg
      421 ataacatgtc cgacacccat agcttcggtt acttctacat tgtgtttttc ggctaaagct
      481 aatgcttctt ccaatgtcat ttcttgccag aagtctacac cagtttgttc tttgattgca
      541 tctaccatat ggatgcgttt aaagtcactt tctaagtcga cagcttgtcc atcatatgtg
      601 atttttgctg ttcctagtac tttttcagct gcgttacgga taataccttc tgtcagattc
      661 attacatcat tgaaatcagt atatgctgtg tatgcttcta acatcgtaaa ttctggatta
      721 tgtgtagtat caattccttc attacggaaa acgcggccga tttcataaac tttttccatt
      781 ccgccaacaa ttagtcgttt taaatgaagt tctagcgcaa tacgcaaata taaatcaatg
      841 tccagtgcat tatgatgcgt gataaatggg cgtgcggcag ctccacctgc ctcattgtgc
      901 aatactggtg tttctacttc aatatagcca ttgccatcta aatagcgacg gatttcgctg
      961 ataatttggc ttcgtttcat aaatcggtca aagctttcgc gattactgat taaatccaag
     1021 tagcgttgtc tgtagcgttg ttcaatattc gttaagccat ggtatttatc tggcagtgga
     1081 cgaagtgctt ttgacaaaat cgtgatttct gaagctttga tagaaacttc gcctgtgtct
     1141 gttttcatga tttgtccagt tacaccaaag aaatctccaa ggtctgcatg tttgaatact
     1201 tcataggcct catcacctac ttggtctttt cttacataaa tttgaatttg gccttcacga
     1261 tcttgtagat gcgcaaatcc agttttccct tttcctcggc gagtcatcat acgaccagct
     1321 acactagcgg tcaatcccat ttctgctagt tcttcttttg ttcttggatc aaatagttca
     1381 tgcaattctt ctgagttgtg cgtgcgttca aatcgttttc caaatggatc gattccatct
     1441 tcacgcaatt gttccatttt ttgacgacgt acaagcattt gatcatttaa atcttctact
     1501 tgatgttgtt gttcctgtgt cacaaaagtt cctccattct catgttaatc tctttcctat
     1561 aatgccaatg aaacacaaaa aaagcaagcc gaacttggaa tttcggcttg aaaattcacg
     1621 aaaaacttag aaatcacaac gtttgtttca atagtacttt ttccgctttt tctacaaatt
     1681 gatccagcag gtcattgatt tcttgctgtt tttctgtctg attgattgct actttcactt
     1741 tcgctgctcg aggaatccct tttaaataat aagccgcatg tgttctgaat tctctacaat
     1801 ctactttttc tcctttgaga tctgctaagc gttgtaaatg aagtttagct gtagcaattt
     1861 tttcggctgg tgttggttca ggaatcagtt ctcctgtttc gagataatgc tgtgtgcggt
     1921 gaatcatcca tggattgccc agcgctgcac gaccaatcat cacaccgtct gcaccgacat
     1981 agtcaagcat ccattttgca tcttctggcg ttttgacatc cccgttcccc ataaatggga
     2041 tcgtcaaatg ttttttcact tctttcaata cttcccagtc cgcttttcct tcatacatct
     2101 gaacccgtgt acgtccatgc atagcgatgg cacttgctcc agctgattgt gctgctaatg
     2161 cattttctac agcaaagacg tgctcttcat cccaaccaat acgcatcttg attgttactg
     2221 ggatatttac tgctgaagaa acagcttgga ccatttcgta tactttctca ggatctaaaa
     2281 gccattttgc tcctgcttct gctttgatta ctttatttac tggacagccc atattgatat
     2341 ctattatatc ggcagctgtg ttttcttcga caaattgagc agcttcaact agactatctt
     2401 tatttccgcc aaatatctgt aaacttaatg gatgttctgt ttcttcaatg tggagcatct
     2461 ctaaagtttt tttgtttctg aaatgaatac cttggtcact gatcatttca catacgacta
     2521 agcccgcacc aaattctttg acagtgactc gaaatgctga atttgttatt ccagccatcg
     2581 gtgcaacaac gacacgatta gggatttcca cattgccaat tttccatgtg tgttccactt
     2641 aaatccctcc taaggcttct ttcttcaatc catctaattc ttcttcgcta tacttgtatt
     2701 tgttattaca gaaagaacaa accgcttctg caccgtgatc ttcgtctatc attgcttgga
     2761 tttcttctgc acctaacgcg ataattgctt ctgcaaattt ttcttttgaa cagtcacatt
     2821 tgaattgaac aggcattttt tccaaaatgt tcaattcttc tgtaccaagc aatcctttca
     2881 atatttcttc tggtgtctgt ccttcatcta agagggtaga gattcttggt gtcgttttta
     2941 attgttcttc gatcttgctg attgtttctt catcggcacc tggcatgatt tggatcatga
     3001 atcctcccgc cgtcttgatg ctgtcgtcag tattgaccaa tacactcagt ccaacagctg
     3061 aagggatttg ttctgagata gcaagatagt aagtaaaatc ttcagcgatt tctccagaaa
     3121 caatcggcgt ttgcccagaa aaaggttctt ttaatcctaa gtcttttgtg acagtaaaca
     3181 ttccttgtgt tccaactgct ccccgcacat cgattttacc ttcactattt agaggaagac
     3241 tgagatgcgg atttttgatg taacctttca catctccctt tccatttgca tctactacaa
     3301 ttcctgttgc tggaccatcg ccttggattc gaacagttag tttgtcttct cctttgagcg
     3361 tcgcaccaag tagcagacta ccgaccaatg tccgtcccaa agcagctgag gaggtgtgcc
     3421 aagtatcatg acgtctttgt gcctccgcta cggtatttgt tgcttgaacg gcgtatgctc
     3481 ggacgaatcc gtcgtgagca agtgccttaa ccaaataatc tttcatttgt tatgtactcc
     3541 tttttccgtt tttaaactca tagtgaatca tactagcaac tactgctttt ttcaactttg
     3601 gaatgcttct tttaaaaata attcagaatc atctagaaaa caggacatca ccctatttac
     3661 aacttaaata aagaaatctc ccgaaaaccg gtttttgttc cggttttcgg gagtcatatc
     3721 agatcaattg acctatattt ttttatttgt attgatcgtc tgaatgatta tcttctgatt
     3781 gttgagaatc tgaatcatgt tctgctttat tttcctcatt cagttcatgt tttgcttctt
     3841 caaaatcacg tttttcttcc gcttgttttt cagcgtcttt ttcttccaaa gcacgttttg
     3901 cttcttcaaa agttttcgct tctttttcgc ttggataatc atttgactca gtaccttcag
     3961 gcatcacacc gtgttcaaac aatgacttga ttgctttggc atccaatgtt tcgaattcca
     4021 aaagtttttc agcaatcagt ttatgctgtg cacgatgagc ttcgatgatt tctcgagctt
     4081 tatcatgagc ttccatcaag atttttcgta cttcttgatc aatctcgaaa gcgacttgtt
     4141 ccgagtaagc ttttgtttga ccatagtcgc ggccaacaaa cacttgatgg tttccttcat
     4201 attgaacagg acctaaacga tcactcattc catattctgt taccatgctt cgtgctagag
     4261 ctgtcgcttg ctcaaagtca ttggaagcac cagttgattg gacattgaag atgatttctt
     4321 cagctgtacg tccaccaagt aagcctacga tttgttcaaa catatcttct ttcgtcatca
     4381 agaactgatc ttcttttggt aaagcgatca tatatccgcc ggcgcgtccg cgagggatga
     4441 tcgttacttt gtggacgacc cgagcgcgac tcaatactaa tccgacaatc gtatgaccag
     4501 cttcgtgata agcaaccatt tcgcgttctt ttttgctgat tacgcgatct tttttagctg
     4561 gacctgcaat cacgcgatct tccgcttcat cgatatcaga agcatcgatt ttctttttat
     4621 ttcttctagc agctactaac gctgcttcat tcaagacatt ttctaaatct gctccggcaa
     4681 aacctggtgt ctgttgagcc acaactttca agtcaacgtc atctgccatc ggtttattcc
     4741 gtgcatggac tcgcaagatt gcttcacgac cttttacatc tggacgtcca actaaaatct
     4801 ggcggtcaaa acggcctgga cgtagtaacg ctgggtctag tacatcagaa cggttggttg
     4861 cagcaatgac gattactcct tcatttccgt cgaagccatc catttctaca agcaattggt
     4921 tcaatgtttg ttcgcgttca tcatgtccgc cgcccatacc ggcaccacgt tgacgaccta
     4981 ccgcatcaat ttcatcaatg aaaatgatag ctggtgcgtt tttcttcgct gtttcaaaca
     5041 aatcacgaac acgacttgct ccaacaccga caaacatttc tacgaaatca gaacccgaga
     5101 tcgagtaaaa cggtactcca gcttctccgg caacagcttt tgctaataag gttttacctg
     5161 ttcctggagg tccttctaaa agtacacctg ccgggatacg ggcacctaat tcaacaaatc
     5221 ggcgaggatc tttcagaaat tcaacaactt caactagttc ttgtttttct tcttccgcac
     5281 ccgctacatc agaaaaacgt acgcgattag cttttttgtc tgcttctttg gcttttgatt
     5341 taccaaagtt catgacacgg ccgccaccgc caccgccgcc gccttgttgt cccatcatca
     5401 tgtaaaagaa aaagatgatg attacgattg gcaagaagct aagcaatagg gaaacccata
     5461 taccgctgct tgattcttct tttactgttg tagcaacttt gttttctttt gccagttctg
     5521 ttacttggct caatgttgta tcatttggca aaatgattgt tgtgaaatgg gtagtagtcg
     5581 tatctgttga acctaagata gctaacccac cgctgttagc gacggtctgc tgttctttgt
     5641 attcaccagt gatcttatat acaccatttg caggctgcac ttcaaattct ttgatcttgc
     5701 ctgcttgtag ttgttctgtg aattttgagt actcgatatc tgacgatcgc tggccgttat
     5761 taccaaaaat gaaataaacg accattacca tcgctaagat tacgaggaca taatacaagg
     5821 catttttcat catgccgttg ttctttttgt tcatagttgc cctccctaag cgtcaattta
     5881 atttaacagt tttttatcaa tcctgaccat tctattgtac cataatttaa ttgagataca
     5941 gcattaattt gattgataaa cactaggttt caatacaccg atgtacggaa ggttacgata
     6001 tgcttctgca taatccaagc cataaccgac cacaaattca tttggtacgt tgaagccaac
     6061 ataatctgct tcgatattta ctactcttcc ttcaggtttg tcaagtagtg taacaatttt
     6121 gactgatttt gctttgcggt atttgaaaag atccactaaa taagcaagtg ttcttccgct
     6181 gtcaatgata tcttcaacga tcaacagatc gcgaccttct acattcgtat ctaagtcttt
     6241 gacgattttt acttcccctg acgagactgt tgcattcccg tagcttgaaa catccatgaa
     6301 atccaattcc aaatacgtat cgatagaacg aacgatatct gccatgaatg gtaccgctcc
     6361 ttttaagaca cctactacta ggggattggt gttttggtaa atttctgtta actctttgcc
     6421 tagttctttg caacgaactt gtatctcttc ttgtgagatc aaaattctct caatatcctt
     6481 ttccaacatc aggttctcct tccaattgct tctttttgat atttgtaaag aagtatgtag
     6541 tgtattttat cagtttcttc acgaatactc aaatatgaaa aggcaaaagg tatcaagcta
     6601 tatatatttc ttttggcatc tgtaatgatc caagcatgct gcctttgtga attaggtact
     6661 ttctgatcga taaaatatct agatactttt tttgtgagat tctctgttaa tttaatgcgg
     6721 tctcctgctt ttcttttttc gacatacagt tgcacatcag caggaatcca aatgtcatga
     6781 gaaaatagag accatgaatc tgttgctttg atgtcccctg cattttcagg tttgaccaga
     6841 ccaatccatt ctgtttcatt caaatatatt ccttgttctg gaatcagcaa caagcgctgg
     6901 tcttctgtct ggctagttgc ttgtttttct tttttagaga gtacaacaaa atgatactct
     6961 cttttcagta tccaattatt gccaatactg agttgccatt ggcttttttt ctgttgccac
     7021 tggtctaaaa tcgactccat ttgttgttct ttcaaaataa ttcctgtttt tgagaatgct
     7081 ttgtcgaaaa aggagtaaaa aaaatagtat cgttcagcat ctgtcatttc ttcaatcatt
     7141 tctgcagaaa atcgaaattg ttcctcccac tgttcgactt ccttttcgat caactgtccc
     7201 atatattttt gaatgacttg gtctgcccat tggatctgtt gcgaaaattg ctggaaatgt
     7261 ctcaacgcct gtgtattttc ttgtttcaat tgaggaacta ccaaatgacg aagccgattt
     7321 ctctggatat ctaacaattg gtttgtctga tcctcaaagt aaacaagctg cgattccgct
     7381 gcataagtat ataggtcttc tttgctaaaa ctcagcaacg gacgaatcag tctgcccgta
     7441 gcaaatggtt gtacttcttt gattccagaa aaagtattta actgtccccc acgaacgatt
     7501 ttcattaaca ccgtctcgat ttgatcatct ccgtgatgag cagtcatcaa cgtgtcatat
     7561 tgtccttctt ccatcacgcg agtgaattct tgataacgaa agttacgagc ttctgtttct
     7621 atggcggatt tggctggatc ttcccaaata cttacatata aagggagatt cttctcttca
     7681 caatatgagc gaagataggc agcttcttct gctgattctt ctcttaattg gtgattgatg
     7741 tggacgatac ctaaagaaaa accgatttgg cgttgcactt gtaaaagtaa atggagcaaa
     7801 accatcgaat caacaccacc tgataccgct gctaaaattc tcgatccttg ttgccagaat
     7861 ccttgttcat tcccgtgccg aataaatgac tgctgtaata gcggtgcttt tttcccgcct
     7921 ttttcaacgt tcatcctttc cacacccttt cttcctaaaa aaaagagagc gggaaaacgt
     7981 ctaaaacgac aattaacctg ccctctgttg atactatgac ccaaatagtc gcactatcat
     8041 tatttgcggc tttttagctg cgacgtccgc cacggccacc gcgctttcct tctgtgtttc
     8101 gcttcaatga agataagcgg tcatcgctat ctttcaaaaa tgaactcatc aatgaatcga
     8161 agtcttcttt ttgagctgaa ggttgactgc gagaaaaaga ttttttctgt gctggacgat
     8221 ttcggttgtc acggggatct ttttgttgat attttttagg acggctttct tctccagatt
     8281 cagcaggttg ttcctgcgct ttccggatag atagtccgat ttttccatca tcatttactg
     8341 aaataacttt aactgttact tcatctccta cacttaaaac atcatggatg tcttttacat
     8401 agccatttga cacttcgcta atatgaacta gacccgtttt tccagcacct agatcaataa
     8461 acgcaccaaa atttgtgatt cctgatactt ttccttgcag ttttgctcct acctcgattg
     8521 acataaaaaa aatgttcctc ctaattattt ccctttttta tattcctgct tattttgcag
     8581 ttgtagaact agttgattga tctgtttcat ttgtcgagct gtctgtattt gattctaata
     8641 taggataaac tttttcaccg tcttttgagt aaaagaattt gcttctggca agtttagcta
     8701 catactcatc atctttcagc aatgaaacat cttggtgcag ctgatcaacg tctgcgttga
     8761 cttctttcat ttcagtattt gcttcgactc tcaattcgtt caattgatgc atcctttgca
     8821 tgtcatggaa aatctgcaca cctattatcg cgaaaatgac caaagcacca acaaaaattg
     8881 cagccagtct gcgtcttcga aaaatcagtt gacgttgttg ttgctgaaat tcagcatact
     8941 ttttctttgc atattccgta tctagcgcag cgattttatt gctttttttc gtcacttgga
     9001 ttcgctccaa tctttttgat tgtctttttc attataccaa tatcgtgaaa gcttgtctaa
     9061 tctatttctc tagtgtttct gtgcgatttt cagaaataat ttcgtacatt ttttgtgcat
     9121 cttctttttt ggttgattca tgtaattccg taattttcac ttccaacgtt ttgttgccaa
     9181 actggacttt caaaatatcg cctactttga catcactgga agatttcgcc aatttaccgt
     9241 tgatttgaat tcttccttta tcagctactt cttttgctac tgatcgtctt ttgatgattc
     9301 gggaaatttt taaaaattta tctaatcgca tatcttattc ctcacttttt aattttttta
     9361 tttaatcgca ggattttctt accaaaaggc aacattagcc attctcgtac tgtaaacaga
     9421 cgaagacgaa tcactgcata aatgaacaca gaagccccga tcccaactcc tatcacgctg
     9481 acaaaaaaag cagtggaacg atgagttaca ggaccaaata ctatattcaa tacaccataa
     9541 tacagcagca gtactactgt catacaaaga aggctgaaca tcaacttccg tccaaaatgc
     9601 cgttctttcc aaaaagcatt tagctctttt gtttcaattc gaacaaaata ccaaagcgtc
     9661 acacctaatc ctaaaagggt agacaggctt gcacctgctg ttcctaataa accggtcaga
     9721 aaagaagtag tcaatccttt taccaatagt ccccatcctg cgccttttaa agaagggcga
     9781 aacgagttct tgctttgagc aatactttga taagcttgga tgactgcagt gaaagcaatg
     9841 gaaaaaacaa ataatacaag cgctgcattt cccgcataat ctttaaacaa cgcataattg
     9901 atataaggga gcagcaaggc taatcccaaa gacgcagcta atgctaaagc ggtcgtcaat
     9961 ctaagataga ttttggctgt ctgtaaaaac tgacgataga tccggttggt caaatgacga
    10021 gtcaacgcag gcaggaatgt cgcacttaat gcagtggcaa tcactaaacc taattgtact
    10081 aaaggctgac ctcgatcata gacccctttt gctatcttcg caccgtattc tgacagtccg
    10141 taaacttcca aagcattttt tacaaagaaa gagtcgatca gctggaaaaa gataagcaat
    10201 ccactataaa tcgaaaccag tccgccttct accagaaaac gccggatcaa gggctttgac
    10261 ggctgtttga acaatggaaa ccgtcggaag cttaacgctc ctccatgaat cttttgttca
    10321 tagtagtgaa ggatcccata tgcgcataaa ccgccaaaaa cagctccact cattgctgcc
    10381 gtccctgttt ggtacaccgt ccatccaagc tttctaaaag caaacgcact acagacaatc
    10441 acaaaaacac gaacgaactg ctcaactact tgagaaacag cagttggttc catcaagaat
    10501 cttccttgga aattccctcg ataaaaagat agaccaggca tcagcaaaaa ggtaaaggaa
    10561 actacttgga tcagcggttt caattgtatg tctcccatca tccaagcaat ccagctgcta
    10621 aatgcaaaga caaacaacca caaaaagaca cctgtccaaa atactaaggg ataaagattt
    10681 tgcaaagctt gctttcgctc gaaaggattc tttctttctg caacgtactt tgatatgaac
    10741 tgcggaagac cggataaagc taaagtcatt gctatcccat aaattggata aacttgctga
    10801 taaacataaa aaccttcgtc gccgactaag ttttggaggg gaattcggta aagggcactt
    10861 aatacttttg ctatgaaaga agcaatcgtc aatacaaatg ctccttgcat gacgcgccgc
    10921 atttctttat gatccaaatc attgctcctt cctacgctga cagatatttt tgctcacgca
    10981 acgctttgac aaacttttgg atttcctgaa gccatactgc ttcttccatt tggttgggga
    11041 tcgtcaagcg tatcaccatc tgttcttttt caacgcctag actggctttt agttttgtcg
    11101 ctgtcagtgc ttcgaataac tgttccacac tatagcgttt tgttccaact ttacttagag
    11161 taaagactat atgcgcctcc tgtttcctta tcgtttctag gagcgctcga tcgccatcca
    11221 ttttgatctg cccaattgtc aagagatgtg ctacttcttc tggatattct ccaaaacggt
    11281 cgagcagatc atcttctagt tcatctagca tttcttgcga atcaagttca cgaattcgtt
    11341 tatagatctc gattttctgc cgttgatctg ccacgtatgt ttcaggtaga tacgcatcga
    11401 caccgaggtc gatctcaaca gtggtcttct ccacttgact attctttcct tgtttacgag
    11461 aaacagcttc gcttagcatt tgagaataca tatcgaaacc gactgcatca ataaatccat
    11521 gctgctgagc acctaagaga ttacctgcac cgcgaatgga aagatcccgc atcgcaatct
    11581 tgaatccaga tcccagttct gtaaaatctt tgattgcctg aagacgtttt tcactgactt
    11641 cgttaaggat cttctgctgc tcatacataa agtaagcata tgcgacacgg ctgcttcttc
    11701 ctacccgccc tcgcaattgg tataacgtgg ataatcccat ataatcagcg ttctcaacga
    11761 acaacgtatt tgcgttcggg atatctactc ctgtttcaat gatggttgta gtgacaagaa
    11821 catcatattg accttcaata aattcaaaaa gcgtattttc taattgcgcc tctgtcattt
    11881 gcccatgagc ataaccgatc cgtgcttccg gaacgagttc ttggatttct tctacttttt
    11941 gttcgatcgt ttctacccga ttatataaat agaatacttg tccacctcgt cccatttctc
    12001 gatggattgc ttcgcgaata gccccaggat ttttttccat aacatacgtt tggatcggat
    12061 aacgattcgc aggcggtgtt tcgattactg aaagatcccg cacgcctaac atcgacatat
    12121 gcaaagttct cggaatcggt gttgcagtca gagtcaaaac atccacttgt gcacgtaact
    12181 gtttcaatcg ttccttatgt tttacaccaa aacgttgttc ttcgtcaatg atcagtagac
    12241 ccaaatcgct aaattcaata tcttttgaca aaattcggtg ggttcctaca acaatatcaa
    12301 cttgacctgt acgcagttgt tcgatggttt ctttttgttg ctttcttgtt ctgaaacgac
    12361 ttaatagccc gatatttacg gggaaacctt caaatctttc cagcatcgtt tcatagtgct
    12421 gctgtgccaa gatcgttgtt ggaactaaaa aggctacttg tttgctttcc tttatcgctt
    12481 taaaggccgc tcgaagcgct acttctgttt tcccataacc aacatcacct acgagtagtc
    12541 gatccattgg tttttctttt tccatatccc gtttgatctc cgctgcactt ctcaactggt
    12601 catcagtttc agagtagggg aaggcatttt cgaattcttt ttggtaggcg tcatcaggtc
    12661 caaaagcata tcctttttct gactctcttg cggcatataa tttgattaga tcgtcagcga
    12721 tatcctcgat ttttgaagag acttttcgct tggttttcgt ccattcactt ccgcctagct
    12781 tattgatgcg aggcgctttg gcttcagagg cgacatattt ttggatcaga ttcagttgag
    12841 taacaggaat aaacagtttg tcgtcgtttt gatacaaaat agtcatatag tcttggtgaa
    12901 cgccatctac ttctagcgtt tccatcccaa tgtatttccc gataccatga ttggcatgga
    12961 caacgtaatc tcctgctttt aactcattat agcttttcaa tcgctctgcg tttgttactg
    13021 tttgacgtct cgtttgtttt ttcgtcgttt tttggaaaat ttctttttct gtgatagcta
    13081 ctattttttc ttgaggaagt tcaaaaccag cctgcaaagc tccttcaact aattgtacct
    13141 gtcctctgat caatgcattt ttttctgttt ctactactaa tatgtcttca tctcgaagca
    13201 tttgttctgc tttgcgtatt ctgtcctttg tcggaataaa gatcacaaca gtctgttttt
    13261 gcttgcgcca acggtccatt tctgttttca gcaatggcat ttgtccgaag aactgttgca
    13321 tcgtccgata ttgaaaatta tggattgctt ggaaacgaag atttcccatc cctttttgga
    13381 agagtgagaa aaaggttgtg gtgaactttt ccttctgcac gattttttgt atatctgctg
    13441 aaaatgtctg ctcagaaaac acccgcaatt cgctgatttt ttgagtctgc cattctgccg
    13501 cttccctttc gatttcccga tttgtttcca tgattcgctg ataatcatca acgactagta
    13561 aactatttga agggaaataa tccaagatcg tcacagattc ttggtaaaga agatctgagt
    13621 agaattttgc ttcttctgtc gggacacctg cttgccagct tgaagtcagc tgaccgaagt
    13681 aatcttgcaa aaactcgcgg tctgcttctt ctgtggtcgc agcaagccgt ttttctagca
    13741 ttttttgcat ttgctctatt ccatgttcta gatcctctgg tccgtagact tgttcactcg
    13801 ttggggaaac ccagatttct tccgtttttt cgattgagcg ttgtgtttct gcttcaaaat
    13861 accgcataga atctatctct acatcaaata gttctacacg aacaggatag gttgtcgtta
    13921 acgggtaaat atcgataatg cttcctcgaa tactgaattc tcccggtttt gcgaccatct
    13981 cttctcgtac atagcccatc aaagtcaatt ggcgaggaag attttccacg tctatctcat
    14041 caccaatatg ccaattcaat tgcgcctgta gccaagtttt cttattcggc agtcgtttgt
    14101 gcaaagatgc gactggcaac aaatagatac ctgctttttt ttcttgaagt gcgttaagcg
    14161 ttgcaactct ctcgcctcgc gcttctggag aagaaaaggc catttcagca gaaagcactt
    14221 catccactgg aaataaatgg atctgatctt gcggaatcac atgttgcaga tcttctgcta
    14281 actgattcgc ataatacaaa tttggcatca gaataatcat gtttttattt gttttcttaa
    14341 acgctcgagc aaatagaagt gttttcgctg agcccgctaa tcctgtgatt agttgtctag
    14401 gcattttttc ttctaaattg ctgacccatt cttttacttg cggatctttt ccgactaatt
    14461 gaataatatc cattcctttt cctccttcct caattgaatc gattcatcgc atccacgaac
    14521 gaatgccctt ctatgagata ttcgactgct ttaacagatt gacacatgct ttcttctatc
    14581 aaaggctgat tttctttgct gaaaggacta agcacatgct ggactactgt ttttttccct
    14641 tctggcctgc cgattcccac cttgattcga tcaaagacat tcgtattcaa atgggaaata
    14701 atacttttga taccgttatg cccgccggca cttccctttt gacggagccg gatttttccc
    14761 actgccagat ccaaatcatc gtagattacg actaattcct ctggataaat cccaaaataa
    14821 gtcattagtg ggccgactgc acgaccagat tcattcatga atgtttgtgg tttgactaaa
    14881 aggatctttt ctccattatg aaaaaattcg gcaacttctg cttcgaacgg attttttttg
    14941 aaagtagctt gatgctcgcg tgcaatttta tccacgacca taaagccgat attgtgtttt
    15001 gtatattggt atttggtacc tgggtttcct aacccgacga tcattttcat ttttgttttc
    15061 cacctaattc taaaaagcag cacaaaaggc tggactgcta attagcggtc cagtccatcg
    15121 agcttttttc ttttttatac ttgtcaatgc atagtataac acaaaacaag gcgtttcggc
    15181 taaaagagaa tcgttaataa atgataaaga aattaaaaat ttcttcaaag tttaatgaaa
    15241 taattgatat ataaaaatag tgaaataacg cacatgtaag cttttacata taatacaacc
    15301 ttgttatctg ttatatttta tagccaaata gcgtgacatg gggcttgaga aatgttagca
    15361 taagcatggg aaaaaacaaa tcaatggaag gattgatact aaatgactgc agctgcagaa
    15421 aaaaaagatc atcaaaaagt tattcttgtt ggagacggcg ccgtaggttc tagctatgcc
    15481 tttgctctag ttactcaaaa tatcgctcaa gaagtaggta ttgtggatat caatactgct
    15541 aaaactgaag gagacgcaat tgacttgtct cacgctttgg catttacttc acctaaaaaa
    15601 atctattctg ctacttacgc agacgcacat gatgctgact tagttgttat tacagctggc
    15661 gcaccacaaa aaccaggtga aactcgttta gacttagtaa acaaaaacct aaaaatcaac
    15721 cgcgatgttg tcacacaaat cgttgaatca ggatttaacg gtatcttttt agttgccgct
    15781 aacccagtag atattttgac ttactcaact tggaaattct caggtttccc taaagaacgc
    15841 gtaatcggtt caggtacctc tcttgactca gctcgtttcc gtcaagcact tgcggaatta
    15901 gttgacgttg atgcacgtaa cgtccatgct tacatcttag gtgaacacgg agattcagaa
    15961 ttcccagttt ggtcacatgc aaatgttgcc ggcttgcaaa tctatgaatg ggtaaaaaac
    16021 aacccagaaa tcgatgaaga agctatggtt aacctattct ttggcgtacg tgacgctgct
    16081 tacacaatta tcgagaaaaa aggcgctact ttctatggta tcgcagtagc attagcacgt
    16141 atcactcgtg ccatcttaga tgatgaaaat gctgttcttc ctttatcagt attcatgaat
    16201 ggcgaatatg gattgaacga catctacatt ggtgcacctg ctgttatcaa ccgtcaaggt
    16261 atccaaaaag taatcgaaat tcctttaagt gacagcgagc aagaccgtat ggctgcttct
    16321 gctaagcaat taaaagaaat tctagatgaa gcttttgcta aactagacgc tgaataatct
    16381 ttgaacatga cggaaaacat ctattcggtg ttttccgttt ttttatttta tcacccttat
    16441 ggtttctaaa ttttttcata aagtagagat aaccttcgtc ttttcctcta aattatgcta
    16501 tcatgagacc gttccaccct aaacttttac ttaaggagtt gtcgatatga caagatcttc
    16561 gcatcgaaaa aaatcgaaac atgttgcttt gctttcagtt cttggtgttc tcttagtgct
    16621 gatcagcttt tatacctatc gcagtacata ctacacaaag cattttttgc cgaatacaga
    16681 aataaatgga ataaatgtca gcaatctaac agtcgaaaaa gcaaatgaaa aattaaaaga
    16741 agcttattct gataaaaaac tggctattaa agaagatgga aaagtctggc aggaagtacc
    16801 aaaatccgag ctcggctaca aagatgattt cacttcggag ctttctccga tcctaaatga
    16861 acaaaacgga tggacttggg gaatgactta tgtctcagcg gcagaaaaac aagaaataga
    16921 tcctgtcagt caaaaccacc aaaaactaga cactaccgtt cagacattga caactaagct
    16981 gactgatttg aacaaagacc ggacacctac tactgatgca acgatcgaaa aagcaggtga
    17041 ctctttcgtt atcaagcctg aagtcaatgg aaatacgatc gacgtcgatg ctgcggtcaa
    17101 acaattaaaa agtgcggtaa actctggtaa agatacaatt gaattgactg aattcaaaga
    17161 aaaaccaaaa gtaacatctg aagacagctc actgaaagaa caactcgcat ccatgaatgc
    17221 tatcgcaaat gtaaaagcta cttacagtat aaacggtgag actttccaga tcccatcaag
    17281 tgatattatg agttggctga cctacaatga tggaaaagtc gatttagata cagaacaagt
    17341 acgtcaatat gtaacagatt taggcacaaa gtataacaca agtacgaatg acacaaaatt
    17401 taaaagtaca aaaagaggag aagttacggt cccagttggc acttacagtt ggacgatcca
    17461 aacagacagt gagacagaag cattgaaaaa agcgattctg gcaggccaag attttactcg
    17521 ttcacccatt gtgcaaggtg gcacaaccgc tgatcatcca ttgatcgaag atacgtatat
    17581 cgaagttgat ctggagaacc agcatatgtg gtattacaaa gacggaaaag tggcccttga
    17641 aacagatatc gtttccggaa agccaactac acctacacct gctggagtct tctatgtttg
    17701 gaataaagaa gaagatgcaa ctttaaaagg aacaaatgac gatggaacac cttacgagag
    17761 tccggtaaac tactggatgc cgattgactg gacaggtgtt ggtatccacg attcagactg
    17821 gcaacctgaa tacggtggag acttatggaa aacccgcggt tcacacggct gcatcaacac
    17881 cccaccaagt gtaatgaagg aattattcgg gatggtcgaa aaaggaacgc ctgtattggt
    17941 cttctaacaa aaataatata taaaaagaaa gcacccgtac gattggtaca ggtgctttct
    18001 ttttattatc taacaatgtg ctacttacat ttcagcagca gtaaagactt ctgaaacatc
    18061 atcatcgtct tctagcttat ctactagacg ttccaattgc tctttttgtt cctcatttaa
    18121 atcaatcgtc gtttgtggaa tcatcgtcaa ttctgcttgc gccaaagtga actctttttc
    18181 caactcatct cgtacagcag caaaatcttc tggtgcagta taaatctcga atacttcagg
    18241 agaagtttgc agatcttctg cccccgcctc taatacatcc tcaaacatcg tctcttcatc
    18301 aacagtcaac ccatcgcgtt caatagcgat atatcctttg cggtcaaaca agtaactgac
    18361 tgaacccgtt tctcccagtg atccaccgtt tcgagtaaaa gctactcgga catttgtcgc
    18421 tgtccgatta cggttatctg tcaatgcatg gactaagatt cctactccac ccggaccata
    18481 tccttcatac gtgatttcat cgtaattcgt ttcatctacg gcactcgtag cctttttaat
    18541 cgcccgttcc acattgtcgt taggcatatt tgcagctttt gctttgtcca caacaagccg
    18601 caaagctgga ttcatagatg gatcaggacc gcctgcttta gctgccatat aaatttcacg
    18661 agaaagtttc tgaaagactt tccctcgttt tgcatcttgg gcattttttc ttccttggat
    18721 attatgccat ttactatgtc ctgacatgat ttttcctccc ttgttctttt gagaatacac
    18781 ttctattcta gtactatttc acaaaaaaac aaagccacag ccaatctata aacgcttctt
    18841 gaatgccgca aaaagcacac ataatatcac agcagtcaga gcaccgatcg aatccaacat
    18901 gacatcttgg aacataggtg ttcgtccacc ggtcatcatc tgatggaatt cgtccaaacc
    18961 tgcgtaccct gttgctgaaa gccaagcaag gatcgctgtc agccaccaaa tttttagctt
    19021 ggggaaaaca cctaaaaaca agctgcctcc caaaataaaa taggtaccga aatgtgcgcc
    19081 cttccttaaa aagaactcta aaaatttggc gtagcccaga tggtcgatac tcaccatact
    19141 tccaccataa ttaaaacgta tacccgctaa tgtgtcttta aatggctgat taggcagcca
    19201 gctttctaat cgcgaaactt gtgattgctg tccgtaagtt tgagaagaac tgtaaaataa
    19261 gattataacg actatcagtg cgattactaa ataaatattt ccgtttttca tttgtttttt
    19321 tgaagaattc ataagtcacc tctgtatttt atcttagact ttttttgaag aaacaacaat
    19381 cattttcata gagacttctt ccataaaaaa gtgctatact taattttgta ttacaatatg
    19441 aagggagttt tttcatgagt tattcattaa attggaatct agattctatt ttttccggag
    19501 gcagtcattc tgatgctttg aaccaacgga tgaagcaatt ggaagaccaa atgaacgagt
    19561 attatcaccg cgtaacaaaa tggtcaccta gttctgacaa tgcagagcag ttaaacgcta
    19621 ttcttcaatt gcaagaaacg attacgaatg gttttaccca atgcagcagc tatattactg
    19681 cattgctttc tgccaatgtc aatgattcag atgcaaaggt cttatcaggc aagctttacg
    19741 caatgctgcc tcgtctgcaa tcagccgaaa ctgtattgtc aaagaaattt gcagaaatat
    19801 ctgacaatga ttggaatcag atgctttctc aatcttcgtt tgaaacaatt gcttttcgtt
    19861 taaacgagat tcgtcgtgat ggctcacaat tattatcaga agctgaagaa aacattataa
    19921 atacgctttc tttagatggt ctaaatgctt ggagcagtca ttatgatacg attgtagcca
    19981 gcatttcgat tcccttcgaa caagatggac aagtagtcga attatctgct ggacaagcct
    20041 tcaataagat gatgggcgat ccagatccaa aagtcagaga aacacttttc gcagcatggg
    20101 aagaagcctg gaaagaaaag gcacccctct tcacggatac tttgaatcat ttagatggtt
    20161 ttagactttc tgactatgaa cttcatggtg tcacagattt tctacaaaaa ccattagagt
    20221 acaatcggtt gaagaaagaa acattgtctg tcatgtggga tacaatccag aaaaacaaac
    20281 aaccccttgt taattacttg actagaaaag ctaatctttt cggtaaagaa aaaatggaat
    20341 ggcaagatca agatgcacct attattttag gcgatttgaa agaaaaaacc tttagttttg
    20401 acgaagcagc agcatttatt atcgaaaact ttaacaaatt cagtccaaaa atggctaaat
    20461 ttgcccaatc tgcttttgaa aagagctgga tcgaagcaga agatcgtcct gggaaacgtc
    20521 ctggtggtta ttgtactgag ttaccagaaa caaaagaatc aaggatcttt atgacctaca
    20581 gtaattctgt taatgaggtt gcgacacttg ctcatgaact aggacatgct ttccatagca
    20641 gcacgatgtg ggatttacct tctttaaatc gcgaatatgc catgaatgtc gcagaaacag
    20701 caagtacatt cgcagaactg atcgtagccg atgctacatt aaaagtcgca aaaacaaaag
    20761 aagaaaaaat caatttgcta gatacaaaac tgcaaaatgc tttagctatg ttcatgaata
    20821 tccattcccg attcattttt gaaaatcgat tctatgaagc acggcaagaa ggattagtct
    20881 cagaagataa gatcacagag atgatggttg aggcgcaaaa agaaggctat caaggagctt
    20941 tagctactta ccatccatat ttctgggctg caaaattgca tttctttatt gatgacgtac
    21001 cgttttataa cttcccatac acatttggct acctctttag tttgggcatc tatgcttacg
    21061 ccaaccaaaa gggagcaaat tttgaagaag aatatatcca tttactacgc gatactgcct
    21121 caatgacgac ggaagatctt gcgaagaaac atttgaatgt cgatcttacc caaccagatt
    21181 tttggcaagc aggtatcgac atggtgactg aagatatcca aacgttcatg gaattgacag
    21241 aagaatttat ctgatttcta ttttatcaca ataaaaaaag agttagtcca gaatgggcta
    21301 actctttttg attaatcatt cttacatgct gacagcaaag tcaggggcaa accattgaac
    21361 tgaaccaact tttacgcttt cgcctggttg aggagcatgg atatattgtc ctccgcctaa
    21421 agcaatcgct acgtggtaag ttccgccttg tgacccccag aataacaagt ctccagcttt
    21481 tgcttgagaa actgaaattt ttgttccagc tgattcttga ggaactgtcc aaccaccgat
    21541 gtcacgacca gttacttgca tgtaaacata gcgtgtgaac cctgagcagt caaagccact
    21601 tggatcttta ccgccccaaa catatggagt accaatatat ttgtaagctt ctgctacgat
    21661 tgctgcacca ttcacacttc cagaaggagc tggagcaggt gttacaggtt ttggttgttc
    21721 aggtgttggt gttggcgttg gagccggagt actacttcct gtgccgtttc ctgtatcaac
    21781 actttgatct gttgatggtg ttgtaggcgc aggtgttgtt gattcttctg ttgttgaaga
    21841 ttcaggcact gttgttgatt cttctgttgc tgaagattca ggcactgttg ttgattcttc
    21901 tgttgctgaa gattcaggcg ctgttgttga ttcttctgtt gctgaagatt caggcgctgt
    21961 tgattcttct gttgaagatt caggtgttgt tgattcttct gttgctgaag attgtgtagc
    22021 tgatgatgat tcttcagtca ttgaagattg tgtagctgat gattcttctg ttgctgagct
    22081 ttgtgcagta gatgaagctt gagtagcttg tgcttcagcc tctgcttgtt cgcgtgcttc
    22141 tttttcagct ttttcttgtg cagcttgttg acgagcttgt tctgctagac gttgttgttc
    22201 acgaatacga gcttgctctg cttcagcttc tgctttttga cggttcaagt cagctttctt
    22261 gtcttcagca gttgcttgtt cagcagctaa tgaagttttc agtacgttca aatcagcttg
    22321 tttagataaa agatcgcctt tttgagattc caaagcagct tggttttcag ctaattcttt
    22381 tagtttagca tcgttttcag cttttttgtc ttctacagct tttttatctt gtttttgttg
    22441 ttccatcaag tcgttgtttg cttttaccat cgttgtcatt gcttgaacgc gtccaatagc
    22501 atctgctaat gaatcagcat tcaatacagc atcgatgtag tttgagcttg tgttgcttac
    22561 ttgtgcttcg cgtgcttgtt tttggattgt atcttcacgt ttttcaatac gttcttgtaa
    22621 atctgcaatg tcttttacta attgtgcaga ttcttgacgc aatgtatctt gttttgctaa
    22681 taggtcttgt gcttgtgtgt tgatttcaga aacttggctt tctaaggcat cgatttgtga
    22741 ttgtgcatct gcttgttgat ttttcaagtc tgcaatcttt tgatcttgct gttgtatctg
    22801 agaatcaaaa tcgtccgccg cggcagcgat cggtgatgct acggcagtca aggtcattga
    22861 acataccatt actgctgata ttaaactctt tttcactctt cattcctccg actggcttaa
    22921 tttaataaat atctaaatat atttaagtct ttcttaacga tataaaaatt gtaccatagc
    22981 agtgtgtcaa cgatataata gttatgttac aaaaatgttt caaaacaact tttaaaaatg
    23041 acaaaactgt tcgtttcaga aaatgatcat gaaaaagccg cgttaagtct agcatttctt
    23101 aagataacaa cgattctttt tcgctttcga cctaaaaata aaaaaagaaa ttattcatca
    23161 ctgaataatt tcttaaaggg aaaaatgaat aatacaaata taatcatgtt caacagcagt
    23221 gtaggtccta aaaaccttgt aataaaatac gtgttattta ctactgctaa tttaaaaatc
    23281 aactggacca ccatcgtaaa caattcataa cccgtgacaa agatgatcat actgaaaaat
    23341 tcagtaaaga tgttgacatg gataacgtct ttcattacat acatcaacca tacaattaaa
    23401 gggagagcta ctgcatagat accgataacg ccaatatagt aagcgtcata gatagccccg
    23461 agaacaatcg tggtaatcag taaataacgt ttttcaaacg ccatactgca acataataat
    23521 gccaatatca gaaagtgggc atttgacata taggtgcctt tcgaccactc ccctagcatt
    23581 cttgttaaat gaccatctat caacatcaaa aagaacaaaa cgattggcag atagtacttc
    23641 attgtttctt tcttcaacat ggactaatcc tccgctagcc gttggacaat cgtcacaact
    23701 gacacgtcat acatttctgc ataaggtttc acataaactt cccgatccag cccataacta
    23761 tctggtttcg ttttaataac cgtaccgatc ggcaagttag ctggagaatt ccctccaaga
    23821 ccggatgtct ggacaacatc cccttctttg atatccgtat caccagttaa ttgggtcacc
    23881 actaaggcat ggagcttttc atcatagttt ttaagcaaac caaacgcttc gccattagcc
    23941 gaagataccc gtactggaaa atgattggag ctttcattag aggatgacag taattcgatt
    24001 ttagacgaag ccgtattgac ctcgatcact cggccaatca atcctttttg cgacatgact
    24061 gccatatttg cttcgatacc gtctttagaa cccttgtcta cgatcagcat gtcctgccaa
    24121 ctgtcaggcg aacgagtaat gacatttgcc gttacttttt cgtaactagt cagcgtctga
    24181 ttcaactcaa gttctttttt caacgcttcg atttctctct cgtaattctt gttttgctgt
    24241 gaaacgtcat catagctatc gattttttct tttagccgct cattttcggc ataagttgaa
    24301 aaaagattat ggacagaatc tactccattt cgtacccacc gtactggggc agagattgtt
    24361 ttatcaacca ttgcaacact gtcattaacg atggattgga agaaattggg ctttccttca
    24421 ttcgctcgct gcgcagcggt cacacttagt atcgtcacca cgatgataac aataaccaag
    24481 gtaataataa tatttttatt aggattgaac ttcttcacaa agacacctcg aattaattag
    24541 actcttgtgt tcaattttat cactaaatgc cgtgaaacaa aaggtaagtt gctcctctta
    24601 agcttttttt tagcaaataa tagattctgt catttttagc ctgaaagaca aattttttta
    24661 tttgtttatg gatcaatctt tgctttgaat aactgcaatc ataccatctg aaaaagaaaa
    24721 ttctgcggta tctgaaagaa attcgttact tgcataagat gtcggatatt ctacttcttt
    24781 attttccaat acatacttgc tgccttttaa tgtaagattc gagacgggag tcaagcagca
    24841 ataagctaaa tacttcatat ctggtatctg tcttactata tgctctccag gcaaataata
    24901 agacaaataa ttttgacaat ctctgataat aagctgatgg gcaaagggtt tgaagcgagg
    24961 ttccatacct aaccagagat tggctaaaag atgatccaat cttccgcccg tagctccaat
    25021 caaagtgact tccgcttgcg ggtaacgttc aaatgttttt aagataccta actgtgtatc
    25081 tgtatcgtct ttttctgcag gggaacgggt atactctttg gcttttgcaa atacttcctt
    25141 ctgctcttcg ttcgacaatg aatcaaaatc gcccactgcc agatctactg ggtagcctgc
    25201 ttgaagcagg tacagcgcac cacggtctat cccgacatag gcatcgtatt tggacagcag
    25261 agactgcggc cagttttgcg gattacctcc agcagctaat aaaattttca tttagtctaa
    25321 tgcctctttt aatcgttcga tttgtccgac tggattttcg gctccataga tatatgatcc
    25381 tgcaacgaag acatccgccc ctgcatcttt acagattttt gctgtttctg gaacgattcc
    25441 gccatctact tcgattgcat aagtccaatt gttctctcta cgtagatcag cgagttccgt
    25501 aattttttct actgtttctt caataaagct ttgtccgccg aacccaggat tgacagtcat
    25561 gactagtact tgatcagcca aaggcaaaac atgtttgatc atggagactg gtgttcctgg
    25621 attgataact actccagctt taactcctaa gctttttgtc atttgaagtg cccgatgaat
    25681 atgaggagtt gcttcgacgt ggacagtaat gatatctgct ccagcttttg caaatgctgg
    25741 aatgtagttt tctggatcaa cgatcatcag atggacgtct aacggtaatt tagtaacagg
    25801 acggattgcc tgaacaatat ttggccctaa tgtgatattt gggacaaatt ggccatccat
    25861 tacatctacg tggatgtaat ctgcgcctcc tttttccact aactcaatgt ctctttgtaa
    25921 attggcaaaa tctgcactca aaatggatgg tgctatcttc attcttgttt cctcctattt
    25981 tcgtttacct tctttttttg catacattgg ttttcttttt tcgatttctt gtaagaattg
    26041 caaataattg tcgtaacgtg tctgtgcgat accacctgtt tctactctat gttttacttc
    26101 gcagccaggt tctttagcat gcatgcactc tctaaatttg caatggacag aagcttctac
    26161 aaattcagga aattgtctcg gcagttctcc tgcttcaatt gtcaaaaagt caatcgagct
    26221 aaatcctggt gtatctgcta ctaacccgcc atagatagga atcagttcca catgacgtgt
    26281 tgtatgccgt cctcttccaa gtgcatcaga aatctctcct gttgctaaat tcagttccgg
    26341 tgatatttga ttcagtagcg tcgattttcc tgctccagac tgacccataa agaccgatag
    26401 ccgttctggg aagtaacgga tcagttctgt cgtatcaccc gtatgattgg gtacaatcac
    26461 cggatagcct attttagtat aggtttgctt gatctcttcg attttttctg ggtcgtctga
    26521 caagtcggtc tttgtcaaaa aaataatcgg ttcgatcgac tcgtattcca aggtaactag
    26581 aaagcggtca agtagattat aagaaaatgc aggctctacg atacttgtga caatgattcc
    26641 aagatcaaca tttgtgactg gtgggcgaac taattgattt tttctcggca agatttccag
    26701 aagatagccg tctgtttgat tttcactctc aaagatcacc tgatctccga caagcggcgt
    26761 gattttccga ttccggaaat ttcctcttcc tcttgtttga taggtctctc cgtttgcgta
    26821 tacatagtaa aaaccgctga ttgcttttct gatttgtcct ttgataagtg ccacctccgt
    26881 ttttgtttat tttaccatac gaagaggaaa gtaggtgtta ttccatgcaa acttctcaaa
    26941 gtatatggct tgaaaattga tcaaaagaga tagaaacaca aaaaagagaa tgcaacaaat
    27001 caatgtcgca ttcccttctg atatatttta ttcagcactt attttgaact ttctgaggtg
    27061 ctagctgatg aacttgtgga gctggaagat tcttcttttg aagagttgct tgtgctactg
    27121 gagctacttg agctgctaga actgtctgaa gagtcttttt cagaactaga agacgctgga
    27181 tctggtcctt tagagtaaat tacgttcaca accattcctt tggtaattgt cgttcctgcc
    27241 cctggtactg tacgaatcac tttatcttta tccaccgtgt ttgaatattc ggaagtctca
    27301 tgcccgatat attctgcacc gacactagct aaataacttt gtgcttcgct ttttgtatag
    27361 ccggagatat cattcaattt aggctctgtt ccttggctta cgacaaaatt gatgtaagtt
    27421 tcttctgcta caacttcacc cgaggctgga tcctgactga tgatcgaacc tgatggtaca
    27481 gtgtcgctat agtcataagt agcactaata ttattgatat tgaatccttg tgtaacaagc
    27541 caattacgaa cagtttcgta gttttctcct acatgactac tcaaagtcac tgtttctggt
    27601 cctttgctga ctgtgaaagt aatcgtgtct gttttaggat cgacttctgt atcttctgat
    27661 ggagattgcg aaatgatcat tccgctttct acctctgaac tgaattcctc ttctttttga
    27721 atcaagtcag cagaaaaccc taattctttc aaacttgctt cggcatcttc ataactttta
    27781 ccactgtaat catctaattt gatttttttc gtgccgctac taatatacag agtgacttcg
    27841 cgtttttgct tgactgtcgt tcccgctgcc gggtctgtct tcactacatt accttcttcg
    27901 attttgtcat ctgcaatttc ttctgttttt gttgctactt ctaatttcgc ttttgcgagt
    27961 gtttctctag cagaagcttc agaaagatca gaaacatcag gaacaacaac ttctcctcgc
    28021 ccgccagaag caaagaatac agctgttccg attcctaaaa cagcaagaat agctaatagg
    28081 atcagccacc attttttctg tcctttcttt ttaggatcag gcagaacttc ttcctcctct
    28141 ggcaaggttt cgttttctgg cttgtctttt ggcagaggca tagatttgaa tgaatcaggc
    28201 attggtgcat cttccgtaag gggtgtgata acttttgttt cattatccat cacatgaggc
    28261 tgccattttt cttcgtttgc acgagctggt gataatactg tagaaagatc atcagacatt
    28321 tcctcggctg acttataacg gtctgcaggt tctttagccg ttgcccgtaa aatcacgttt
    28381 tccagtgctt gtggcacatt tggatcaagt gcttttatag atggaagatc atcttgaaaa
    28441 tgttttaaag caattgttac agcagattca ccatcaaacg gtacgctacc cgtcaacatc
    28501 tcataaagga tgatccctaa agcataaata tctgactgct tcgttgccat acttcctctg
    28561 gcctgctcag gggacagata atgaacagat cccagcatcg tattcgtctg cgtgatcgat
    28621 gtttcagata aagcgatagc aatcccgaaa tccgtgattt ttacaacacc ttcattatcg
    28681 atcagtacgt tttggggttt caaatctcgg tggatgattt gatggttatg agctaaagaa
    28741 atagcagaaa ggatctgctg cataatattt actgctgttt cataaggaac aggataatgt
    28801 gtttggatat atcgtttcaa gtccattcct ttgacgtatt ccatcaccag atactgcatg
    28861 ttgtcttctt caccaacatc gtaaacacta acaatgtttg gatgaacgag ttctgttgct
    28921 gctaaagctt ctctctgaaa tcgtcgaatc gcagtctggt cattttgaaa gtcaaatcgt
    28981 aagactttaa ctgctacatc acgatccaag attaaatcgt gcgccaaaaa tacatttgcc
    29041 ataccaccgc taccgatatt tccagtgatt tgataacggc catttaattt tttgcccaac
    29101 tcgatcatac actgtcctcc ttatattcga taagaagaac ggtgatatta tccgctccgc
    29161 ctgcttcatt ggcacgatca atcagctcag ttactttatg agacaatggg ccttcttgat
    29221 tgatgatcgt tcctatttct tcttcagaca gcatgttcgt caagccatct gaacataaca
    29281 gcagtcgatc ttttagttgc caaagatgag tagaaacatc tacttcgact gttccaggca
    29341 tgccgacaga acgtgttaaa atatttttcc ttggatggtt cactgccatt tcttcgctga
    29401 tttctcctga tttgactagt tcattgacta aagaatgatc ctccgtcaat tgcatgattt
    29461 tatcttcacg aatcaaataa gctctgctat ccccaacatt ggcaatcgtg aaccagtcat
    29521 ctgacagagc ggccgctacg attgttgttc ccataccgtt atattccggc tgttcttgtc
    29581 cacgctgata aatcagcata ttttcttctt gaatcgattg aatgaaccat tgggcgattt
    29641 tttcatcgtc aacagcttct tgtttttccc aagcttcgcc tagattcgtt accgccatct
    29701 gactggcaat gtctccggca cgatgaccac ccatcccgtc tgctaataca gcaagcttga
    29761 gacctgaacg gctggtaaat acactggcat agtcttgatt tgtgttacgt cgtcttccta
    29821 catctgattg atattcaatc tgcatttttt cacctcatta ctttttgcgc aaacaacaaa
    29881 tgaaaaatcc atctgtgtaa aactgatgcg gatacaaagt caacattttc tcttcgattg
    29941 atgattgtag cataggattg gtcaaaacat caatcctctc aaaatcaggg tgtctttcca
    30001 agaaagcaga aacaacgtct tggttttctt cttttaagat cgtacaagtg ctataagtca
    30061 gaataccgga agactttaaa gttggtgcgc agctttctaa aatttccaat tggatttttg
    30121 gtaaattcgc taattcatcc ggctgttttt tataacgaat atctggtttt cgccgaagca
    30181 gcccaagacc tgaacaaggc gcgtctacta aaatccgatc aaactgctct gcttcgaact
    30241 gtttactgac ttctctagca tccatctttt gagcgtagac agcagaagag acacctagac
    30301 gtgctgcatt atcttcaatg agtttgactt tgtgttcgtg tacatctaaa gcgaccactt
    30361 ctccaccgca tgacggatct aaaaaagaag caatatgcgt cgtcttacct ccgggtgctg
    30421 cacaggcatc taagacatga tgttcaggct cgatttgcat agacggcgct acaagcatcg
    30481 aactttcatc ttggatcgtc atgacgccat cgtggaacaa tgagctagaa gctaaatgcc
    30541 cttttttcgc tactataccg tatggactga cttggctttt ttcagctgtg atctcttctt
    30601 cttgcaaaac agtgatggcc tgatctctgg aaagtcggcg tgtatctact cgggcactag
    30661 catggctagg ctgatatagc gataaaccga gcttttcagt ttcttcgtat ccgatttgat
    30721 ccaccagtcg tttcgtcatc catagaggca ggctgatttt gacagaaagt ctttcgatag
    30781 gatcagcaat gccttgcaga tctggtgctc cttgacgctg ataattcctc aagacaccat
    30841 ttacaaattt ccctgtccca ggatttcctt ttacttttgc gatttcgacc gcctcgttta
    30901 aaatagcatg tgcagggact ttatctaaaa attctaattg gtatacagaa agataaagaa
    30961 gcgtcttgac ccagtcatcc actttttttg ctttagcgat caatggtgca acgtaaaatt
    31021 ccaatagtcg ctgatggcta atcgtaccat agatcaattc tgtaaataaa cccacatctt
    31081 tttgatttag ctcgctttgt ttgatcatct cattcaacaa aagattcgag taggcgccac
    31141 ccttgttcac tcgctctaat gtcagtaatg ccatatatcg tactgatttt ttcatttttt
    31201 tagggatttt tttcattatt tcacctgctg accaatctga acttgctgac cgcttccgtt
    31261 aaggaaatca tgtacggcct gttttccttt accagctggc tgtaattcat tgatggctaa
    31321 gacggtctgt ttaccgcaag caatccatag attttttttg tctttccgga tgatcgtacc
    31381 aggtgctttg tctgtagttt ctgccaatac ttcaaccgat aataatttcc agcgtatgcc
    31441 ctcataggtc gtgaatgcaa ttggccaagg acgcattccg cgtacttggt tgtcaatttc
    31501 ttctgcagtt ttatgccaat cgattgcttc ttgttcccgt gtgatgtttg gcgaaaaagt
    31561 tgcttctgac tcgtcttgag gtactggttt ttgtccatcc aaaatattgg gcaatgtttc
    31621 tagcaatagc tttcttccta aaaggctaag cttttcaaac atcgtcccta catcatcttg
    31681 tttagtgatt ggtatgcttt cttgcgcata gattccgcct gcatccattt ttttgatcat
    31741 ttccatgatc gttacaccag tttctttctc cccattcatg atggcataat gaacaggcgc
    31801 acctccccga tatttaggaa gtaaagaagc atggacattg attgccccta attttggtac
    31861 ttgcaataac ttttcaggca agaattggcc aaatgccgca gtgacgatca catcaggcac
    31921 caattcaatg atttcttcca tttctggcga accggagatt ttctctggct gcagcacacg
    31981 gataccgtgc ttcagagccg cttcttttac cggtgtcggc gtaattactc gtttccgccc
    32041 aactggacgg tcgggctgtg ttaccactgc ctggatctcg taacctgatt ctatcagccc
    32101 ttcaagaatc ggcacagaaa aagcaggtgt gcccataaat actagcttag tcatcaagat
    32161 gttcctccat atattcttca agttcttctt ccgggatctg ctgtatcatt ttctcaatga
    32221 acaagatacc gtctaagtga tcgatttcat gctggaaggc acgggctaaa tagccaaaag
    32281 ccgtcacttc tatctcttct ccgtctcgat cataataacg cacggtcact tcatctgctc
    32341 gcttgaccgt tccatagaca tgcggaatac tgagacaacc ttctacgtca aggctttcac
    32401 cttttgcttc gatgatttct gggttaatca gttcaaattt ctcgccttca tctacttcga
    32461 tcacagcaat tctcttgttt tgtcctactt gaggagcagc gatccctatt ccgtcattcg
    32521 caatcattgt ctcatataaa ttgtctaata aagcgattgt ctcgtccgtg attacatcga
    32581 ttggctgagc agttcttttt aatttatcat tagggtggat caatatagga tagcgcataa
    32641 tttggccctt tcttaaataa agtttaatgg ttcgttgtca attgccacaa aaagaccttg
    32701 tcgctgttct ttctggcttc cattcaaaat ttcatccaaa acatgaggaa gattcggttc
    32761 atgtttatat ttgatgatta gttgataata atatcggttt ttcactctca aaatcatgct
    32821 gggcgttggc cctaatagca agctttgagg gcttaacact tcttttagct gattggcaat
    32881 ctgaaagatt ttctttgccg ctacttgttc ttcaggatgg ctggcggtta ttttcacagt
    32941 aaagtaataa ggaggatagc ctccacgatg ccgtacatgc atttcctgct gataaaactg
    33001 ctcataattt tgttttttag ctaattctat ggcgtaatgt tgaggattga atgtttggat
    33061 cacgacttcg cctgcttttt ccgctcgccc tgctcgtcct gaaacttggg taagcaattg
    33121 gaatgtatgc tcactagaac gaaaatccgg taaattcagg gaggtatcag cattcaacac
    33181 cccaactaat gtcacttctg gaaagtccaa acctttagca atcatttgtg tccctaataa
    33241 tatatctgct tcttttgcac cgaatttttg taaaatctgt tcgtgtgccc cttttcttcg
    33301 agtggtatct acatccatac gcaaaatcct agcttgcgga taaagttctc ggagttcctc
    33361 ttctactttt tgagtacctg ttccatagta gcggatttta ttgccgccac aattaggaca
    33421 gcgattggga ataggttctt catgtccgca ataatggcag cgcattgaac gtgtatccat
    33481 atgcagtgta agagagatat cgcaattagg acatggaaga acaaatccac agtccctaca
    33541 catcacaaaa gacgaatatc ctcgacgatt gagcagtagg acagtttgtt cttttttgtc
    33601 taatcgattt tgtatttttt cctgcaaatt agcagaaaaa gtagaggtcc gatgattctg
    33661 aaactcttca cgcatatcta cgatctcaat agctggaagc tgtgcagctg ctttggctcg
    33721 gtggtttaac tgcaataact gataaacgcc tttttgagct cgtgctcttg attctaaaga
    33781 gggcgtcgcg cttcctagaa ctattgggca atgatgatat ttactgcgcc aaattgctag
    33841 atctctcgca tgataacgcg gtgtctcatc ttgtttgtaa cttgattcat gttcttcatc
    33901 gataatgatc agcccgatat ttttcagcgg ggcaaaaata gcagatcgtg cgcctactac
    33961 tacttgcgct tcttcccgct caatcttgcg ccattcatca tatttttcac cttgggaaag
    34021 tccgctatgt aagaccgcaa ctgattctcc gaagcgtcct ttgaatcgct cgaccatttg
    34081 cggagtcaat gcgatttcag gcactaacat aatagccgtt ttattttctg acaaaacatc
    34141 agcgattgcc tgaagatata cttctgtttt cccgctgcca gtgattccct ccagcaaaaa
    34201 gacctgatct ttttgctgct gacctgctgt gatgatttgt tcgacagcat ttttttgttc
    34261 tgcattcagt tccaatgccg tcgtttggtc aaatactcgg tctttataag ggtcgcgata
    34321 acgttctgat tctataaact ccagccagcc cttttctttt ccttgattca agacagcagt
    34381 actgattcct ttatttttga aataagcaat tggttcttct tggctcagtt cagataaaca
    34441 caaaagaagt tctttttgtt tcttggcatt ttgccgtaat tttgcccatt cttcttcgat
    34501 ttgcttttca gttaacaaag aacggaccaa acgaatcgtt tttactttat ttcgtgtatg
    34561 gacttcatat ttgatatcta ctaattgctc ttggcgccag cgaatcaatt gagaaaggct
    34621 gccttcttct tctgcttcct tccaggaaat cacttctcgc tgatcaaaca atacctgaac
    34681 ttctggtgtg tctgccaaag gatagatcaa tttatcatat tctgctttca tcacactcgg
    34741 aagcatcgtt tgtagacaag tgattttgaa tgcgtaagta atttttttca tataatcagc
    34801 taatgaaagt aattcttcat tgaccaccgg agcaaggtct agcaaacgaa taactgcctt
    34861 caaagatgga ttagctgatt cttctgattt ttggatagcc ataacaaatc cttggacatg
    34921 acgattgcca ttaccaaaag ggacttctac tcgcatcccg acttgcaaag ctgtttccat
    34981 ttcagaggga accaaataag tgaatggctg atcggtctgc atagtaggta cgtccacaat
    35041 gacttcagct gttaatgtca tggttcgttt cctccttttt ttgtcttttc ttatcaagcg
    35101 acaaaaagtt ccttgcctat tttactagag atcgatggat ttgtcttatc ttctgccaaa
    35161 tcctaacaaa aaattaacag cagataagaa aaaaaagaac tgtgtcaaaa agttcagaca
    35221 cagccttttc taccagacaa taagtggcga atgtttgaaa aggaaacagc tgggtttgct
    35281 tttcttttta gatgttcgct ctatttttct ttattacatt ttttgctctt cacggatacg
    35341 tgattccaat tcgtgttgtt cacgctcttt ttgtgcttga cgttcctctt cttccatctt
    35401 caaacgttca cgttttaatt caggatgtgg atcattgact acatttcctg catcgatttc
    35461 ttctaaagct tgaccgacgc tttttactga atcaaaagaa tctagagtag gctgtgcact
    35521 tgcatccaat tcatgcgcgc gtttacttgc taaaatcact agagaatatt ttgaatttac
    35581 acgatctaat agtgagtcaa ttgaaggttt taacatcata agactacatc tcctttaaca
    35641 ttttaatata tttaccgatt acgcgatcta ctcgaaaatg ttcactggca ataatgtttt
    35701 tgattcgttc aactgctagc ggcacttcat catttacaac agcatagtcg taaagagcca
    35761 tcatttcgat ttcttctttt gcaactttca ttcgttcttc gattacttca tctgcatctg
    35821 ttcctcggcc tacgatccgt gattttaatt ccgctaaatc tggcggagtc aaaaagatga
    35881 atacaccatc gggcactttt tctttgactt gttttgctcc ttggacttca atctccaaga
    35941 aaacatcttt tccttcatcc aatgtcttgt tgatatatga caaaggagtt ccataataat
    36001 tcccgacata ttctgcgtat tccagcatct ctccagcttc gatcattgat tcaaactctt
    36061 ctttgcttcg gaagaaataa tcaacgcctt cgacctcccc ttcacgcatt ttacgggtag
    36121 tcattgagat cgaatactga aaatcattat cctcactctc aaaaattgct tttcgtactg
    36181 tgccttttcc tacaccggat ggaccagaca acacgattaa taatccacgc tctgacatga
    36241 cgacgtcctt tcaactagtc tttttgtact tatcgtttat tttgcacttt ttttctgcaa
    36301 ctttcaaggt tatctttaat tatagctaga aattggtaaa aaagctaccc tgtaccaaga
    36361 ggtcgtaaaa aagctgtcct gcatcaagta ataagaacag ccaaacataa acagcttctc
    36421 atgtttttcg tttggttggg gttattatcg cagatgcaag cttttgaacg ccgtgtataa
    36481 gaggtcgtga agaagccgat tagtttcgag tatgaagaaa aattttgtga aaatagtttc
    36541 tcacattttt gcataaattt ggcttaatac
//
LOCUS       DAMEEU010000021        35934 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.022, whole genome shotgun sequence.
ACCESSION   DAMEEU010000021 DAMEEU010000000
VERSION     DAMEEU010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 35934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.022"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(42..662)
                     /locus_tag="PB779_001068"
     CDS             complement(42..662)
                     /locus_tag="PB779_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HDE0738607.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(854..1150)
                     /locus_tag="PB779_001069"
     CDS             complement(854..1150)
                     /locus_tag="PB779_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDE0738608.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1354..2004
                     /locus_tag="PB779_001070"
     CDS             1354..2004
                     /locus_tag="PB779_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HDE0738609.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2020..3747
                     /locus_tag="PB779_001071"
     CDS             2020..3747
                     /locus_tag="PB779_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738610.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3744..5636
                     /locus_tag="PB779_001072"
     CDS             3744..5636
                     /locus_tag="PB779_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738611.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6340..7209
                     /locus_tag="PB779_001073"
     CDS             6340..7209
                     /locus_tag="PB779_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HDE0738612.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7418..8443
                     /locus_tag="PB779_001074"
     CDS             7418..8443
                     /locus_tag="PB779_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDE0738613.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8482..9432
                     /gene="manA"
                     /locus_tag="PB779_001075"
     CDS             8482..9432
                     /gene="manA"
                     /locus_tag="PB779_001075"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HDE0738614.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9526..11229
                     /locus_tag="PB779_001076"
     CDS             9526..11229
                     /locus_tag="PB779_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0738615.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKERGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            11231..13264
                     /locus_tag="PB779_001077"
     CDS             11231..13264
                     /locus_tag="PB779_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDE0738616.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13275..13715
                     /locus_tag="PB779_001078"
     CDS             13275..13715
                     /locus_tag="PB779_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0738617.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13915..15042)
                     /locus_tag="PB779_001079"
     CDS             complement(13915..15042)
                     /locus_tag="PB779_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738618.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15045..15722)
                     /locus_tag="PB779_001080"
     CDS             complement(15045..15722)
                     /locus_tag="PB779_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738619.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            15986..17752
                     /locus_tag="PB779_001081"
     CDS             15986..17752
                     /locus_tag="PB779_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HDE0738620.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17767..18204
                     /locus_tag="PB779_001082"
     CDS             17767..18204
                     /locus_tag="PB779_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0738621.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18217..19368
                     /locus_tag="PB779_001083"
     CDS             18217..19368
                     /locus_tag="PB779_001083"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HDE0738622.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19430..20128)
                     /locus_tag="PB779_001084"
     CDS             complement(19430..20128)
                     /locus_tag="PB779_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HDE0738623.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20121..21473)
                     /locus_tag="PB779_001085"
     CDS             complement(20121..21473)
                     /locus_tag="PB779_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HDE0738624.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21696..23096)
                     /locus_tag="PB779_001086"
     CDS             complement(21696..23096)
                     /locus_tag="PB779_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HDE0738625.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23257..23994
                     /locus_tag="PB779_001087"
     CDS             23257..23994
                     /locus_tag="PB779_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HDE0738626.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24119..24598
                     /locus_tag="PB779_001088"
     CDS             24119..24598
                     /locus_tag="PB779_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HDE0738627.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24595..25362
                     /locus_tag="PB779_001089"
     CDS             24595..25362
                     /locus_tag="PB779_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738628.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25592..26161
                     /gene="lepB"
                     /locus_tag="PB779_001090"
     CDS             25592..26161
                     /gene="lepB"
                     /locus_tag="PB779_001090"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDE0738629.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26265..26867)
                     /locus_tag="PB779_001091"
     CDS             complement(26265..26867)
                     /locus_tag="PB779_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDE0738630.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            26973..27442
                     /locus_tag="PB779_001092"
                     /pseudo
     CDS             26973..27442
                     /locus_tag="PB779_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            27548..28132
                     /locus_tag="PB779_001093"
     CDS             27548..28132
                     /locus_tag="PB779_001093"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HDE0738631.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28135..29208
                     /gene="prfA"
                     /locus_tag="PB779_001094"
     CDS             28135..29208
                     /gene="prfA"
                     /locus_tag="PB779_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HDE0738632.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29201..30040
                     /gene="prmC"
                     /locus_tag="PB779_001095"
     CDS             29201..30040
                     /gene="prmC"
                     /locus_tag="PB779_001095"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HDE0738633.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30033..30212
                     /locus_tag="PB779_001096"
     CDS             30033..30212
                     /locus_tag="PB779_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738634.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30234..31259
                     /locus_tag="PB779_001097"
     CDS             30234..31259
                     /locus_tag="PB779_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HDE0738635.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31450..32694
                     /locus_tag="PB779_001098"
     CDS             31450..32694
                     /locus_tag="PB779_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HDE0738636.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32847..33794
                     /locus_tag="PB779_001099"
     CDS             32847..33794
                     /locus_tag="PB779_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0738637.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33928..34557
                     /gene="upp"
                     /locus_tag="PB779_001100"
     CDS             33928..34557
                     /gene="upp"
                     /locus_tag="PB779_001100"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HDE0738638.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34696..34938)
                     /locus_tag="PB779_001101"
     CDS             complement(34696..34938)
                     /locus_tag="PB779_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738639.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35059..35131
                     /locus_tag="PB779_001102"
     tRNA            35059..35131
                     /locus_tag="PB779_001102"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35092..35094,aa:Thr,seq:cgt)
     gene            complement(35250..35888)
                     /locus_tag="PB779_001103"
     CDS             complement(35250..35888)
                     /locus_tag="PB779_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDE0738640.1"
                     /translation="MNNILGKKIELKKGILGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
BASE COUNT        12094 a         6386 c         7313 g        10141 t
ORIGIN      
        1 attttttcct ctgtctcttt tgtatgcatt tatctcaatt tttaaaatga tttacctaaa
       61 gcagcagctt tatctaatgc attttgcatc aactcatctg cacggtcagg gtcataatcg
      121 attccttcga tgaatagctg atctacttga tcgatgccta caaagtttaa aatacctttt
      181 acatattgag aggcaaagtc ttgtccgttg tatacaccgc cattagattg gatgtgcagt
      241 gcttttttac ctgtcactaa tccttctggc ccgttttctg tatagcggaa cgtttttcca
      301 gctacattga cggtatcgaa ccaagctttt aattttgttg ggatatttag attccataag
      361 gcgtttgcga taacgatttt atcagcagca aggaactgat cagtcaattc attgaaacga
      421 gcaatttttt gttgttgact ttctgataag gaagtgaatt ctgcaccagc acgtaatgct
      481 tcccaacctg ataataattc ttcatcgatt tccggaatat catcgcgata aagttccaaa
      541 acagtcactt catcatctgg atgattttct ttataacttg ttaaaaaaga cgtcaatgcc
      601 ttaactgtgc gcgattcttc tgcagttagg ggatgacctt tgactactaa aacagatgcc
      661 atatgcttac cttctccttt tattgctatg attgttataa ctatgactaa caaaatcagt
      721 ttactcgaaa aagaaaaggc tatcaagtca tattgataag gttgaagaat aaataactaa
      781 aaaaagacag ggtataaaag aggctgtgac acgatttttt gtcacagcct cttttgaatc
      841 taacaagcaa tattcaagca acactcgact gaagagcttc catcccacca atgatataaa
      901 cagcacgaaa accattagca gtaagttgat cggctaatgc ttctgatcgc ctgcctgtat
      961 agcttagaat ataataaagt ttctttggat ctagattttt taattgtctt ggcaagatag
     1021 cagcggggat agaaagcgag tggcttaagt ggttttttgt gtaatctaag gtatttcttg
     1081 tatctaaaac gatgctgtca gcatcgagag gcaatttatt gaagtcttgg acactaattg
     1141 attgggccat ttatctcatc ctttgtttag tatgtggcta ttttaatggg caactctcat
     1201 taattcaaat ggaaggattc ctcttatcac ttttttaatg tatcggatga taatgaaaaa
     1261 aactatgcaa atgtcttgca aaacaggtag gaggtgttat aatgacatag cgtcatatga
     1321 caatgtgtca tcttgaaaga aaggagaatc catatgccga cacagacatt tttccatttg
     1381 cctaaagaaa aacaaaaaag actaatcgag gctgcgagaa tcgagttttc tagagtaccc
     1441 ttaaaagaag cttcgattgc taatatcgtc aaattagcgg atatccctag aggcagtttc
     1501 tatcagtatt ttgaagataa agaggatctt tatttttatt actttgagac aatgagacgt
     1561 gacagctcta aagatatgtt acaactaatg aaagaatccg atggtgatct attcaaagga
     1621 ttcgaatcct atttttctaa aatgatttat gagattttgg aaggcgagaa tgcttctttt
     1681 tatcgtaact tgtttatgaa catggattac cgtgcctcaa gaaaagtcgc tcctcatacg
     1741 agtcgccaaa aaacgcctca cgatccacat aaagaacaca aacaagatgc aaaagagttg
     1801 cttgaattga tcgatcggac gaagctgaaa gtaaaaaatg atcatgaatt ggaattactg
     1861 atccaattag tgatgaatac tgtatttaca acaattgcgc attcgtatcg cttattttca
     1921 acatctgaag attactcagt agagcaagca atcagtgaat tcaatttgaa actttcttgg
     1981 ctgaaaaacg gagtatataa atagaaagaa gggaactaga tgctaaaaat cgtaaaacgg
     2041 atctccttga cttcagcaat tgcagctgca gttttcatgg tgatccaagt actggcagat
     2101 ttatatttgc cgacacttac ctccaatatt attgataaag gggtagcgca aggagatgtc
     2161 gattatattt ggcatacagg ttttgtgatg atcggctttt ctttgatcag tatcttagct
     2221 gctatcgcaa atacattttt tgctactcgt gaatcacaga aactgggtaa gcaattgcgt
     2281 acggatgtct ataaaaaatc agagagtctg acaaaagatg cgtttgataa atatggaacg
     2341 gcctctttga tcacaagaac gaccaatgat gtgactcaaa tccaaatggt tacacaaatg
     2401 tttttacgta tgatgatcaa tgcaccaatc acgttgattg gcgcgagcat acttgcttat
     2461 caaaaagatc atcagttgac aaaaatcttc ttagttgtca tcccagtaat gattattttg
     2521 atcggcggaa tcatgtactt tgctgttcca ttattcaaaa gtatgcaaaa gaaaactgac
     2581 cgtttaaacc tggtatttcg agaaggattg acaggggtca gagtgattcg agcattcgat
     2641 aagacacgct ttgaagaaaa tcgttttgat ttagcgaata aagattatac aaatacggca
     2701 atcaaagtta atacgatcgt cgcattgatg atgccaatga tgacattgat catgagcggt
     2761 acaaacgtag caatcacttg gtttggtgga cactacatag cagatatgac tttggaagtc
     2821 ggtaatctga ttgcatttat gacttatgcg atgcagatct tgatcagctt tatgatgctt
     2881 tccgctattt ttatcatggt gcctcgtgca caagcttcag ctgaccgtat taatgaagtg
     2941 ttggatgaaa aaatcggtat ccatgaccct gaaaatccta aaacagtttc ttttgctgga
     3001 aaaaacgcaa cattggcctt caatcatgtc aattatcgat atcatggagc agaaaaactt
     3061 gcattggaag atattgattt ccaagccaag tcgggcgaga tcgtcgcaat catagggggg
     3121 actggttcag gtaaaacgac cttagtcaat ttgatccctc gattatatga catcgaatct
     3181 ggttcgatcc aaataaatgg aacggacatt agtgacatga ctcaatataa tttgcgagaa
     3241 ttaatgggct ttgttcctca aaaagcagtt ctgttctctg gaacgatccg agacaatatg
     3301 cagtatggta agccggatgc aacagatgaa atgatttgga aagcattaga aatcgcacaa
     3361 gctaaagatt ttgtttcaga gatggaagat ggcttagata gccatgtgga acaaggagga
     3421 ggaaacttct ctggtggaca aagacagcgt ctggcaattg cacgggcatt agtcaaaaca
     3481 gcagatatct atgtgtttga tgattccttc tcagcgttgg atttcaaaac ggatgccaat
     3541 cttcgccaag cattgaaaac gaatatgaaa gaaagtatca ccgttttagt tgctcaacga
     3601 gtaagtacag taatggatgc agatatgatc cttgtgctag atgaaggaaa actggttggc
     3661 aaaggaacac atgaagaact attagcaaca aacgaaactt atcaagaaat cgttcattca
     3721 caactaagag aggaggactt agcatgagta aaacaaacac acgtccctct catggaccag
     3781 caggcggtcc aggacatggt ggacctggca gaaatctcgg tgtaaaaggt gaaaagccta
     3841 aaaatttctg gggaacggta cgccgattgt ttggctatat gtctaaacgt atggttgcga
     3901 tcatcgctgt atttgtacta gcaatagcag ccgtgatctt ccaaatccaa acaccaaagg
     3961 tcttggggaa agcaaccaca gaaatattca aaggtgtaat ggctggcgct caacagatgc
     4021 aacaaggcca acaagtaaca aaatttccga tagactttga taaaatcgcg cagatcattg
     4081 cgacagtaat cgtgatgtat ttgatttctg ctgtattcaa ctttttacag caatttatta
     4141 tgacacgtgt ttcccaacga acagtttatg aattacgtca tgatttggaa gccaaaatga
     4201 atcgtgtacc gatttcctat tatgatacac atacaaatgg ggatatcatg tctcgagcaa
     4261 tcaatgatat ggataacatc gcaagcacgc tgcagcaaaa tttgactcaa tttgtaacta
     4321 gtgcagtcac attgattggg gtcatcgtga tgatgctttc aatcagctgg caattgacgt
     4381 tagtcgcgtt attgatgatc cctttaagct tgatcatcgt gatgatcgta gcgccgaaat
     4441 cacaagtgtt tttcgcagat cagcaaaaaa gtttaggttt attgaataac caagtagaag
     4501 aaacatatgg tggtcatacc attgttaaaa cattcaatca tactgaaaaa gaccaggaag
     4561 tatttgaaaa agaaaatcag aatctgtatg ccgctggttg gaaagctcaa tttatttcgg
     4621 caatcatcat gccgttgatg aatttcgtta aaaatctagg ctatgtgttc gtcgctgtac
     4681 taggcggagt aaaagttgca aatgggaaca tgacattagg ggatgttcaa gcgttcttgc
     4741 aatatacaac acagttctct caaccaatca ctcaacttgc aagtttgatg aacactatcc
     4801 aatcaacagt tgcttcagcc gaacgggtat ttgaagtgtt ggatgaagaa gagatgtcca
     4861 atgaaaaatc tggccttcca gaagaaaaag atacaccata caaagttcgt tttgaaaatg
     4921 ttcaattcgg ctacacacca gataacttgc taatgactga ttttaacttg gatgtcaaac
     4981 ctggtgagat ggtcgctatt gtaggtccga ctggtgcagg gaagacgaca ctgatcaacc
     5041 ttcttgaacg gttctacgat gtttctggag gtagtattcg ttacgatggt gtagataccc
     5101 gtgatctttc acgtgatgaa ttgcgcgcac agttttcaat ggtactgcaa gatacttggc
     5161 tgtttacagg aagtatctat gacaatatca aatatgggaa cgacgatgca acagacgaac
     5221 aaatcattga ggctgctaaa gctgctcacg tagacgattt tgttcgtaaa ttgccagaag
     5281 gatataacac tgtattaaac gaggatgcaa gcaatatttc gcaagggcag cgtcagctaa
     5341 tcacaattgc gcgggcattc ttagcaaatc cagatgtcct gatccttgat gaagcaacat
     5401 ctagtgtaga tacacgaaca gaaatactga ttcaaaaagc gatgaaccgc ctattggaaa
     5461 accggacaag tttcgttgtt gctcaccgct tgtctacaat acgcgatgca gacaacatta
     5521 ttgtgatgaa tcatggttcg atcgtagaaa caggaaacca cgatacattg atggaaaaag
     5581 acggattcta tgcagatctt tataacagtc agttttctga agaagaagct tcatagaata
     5641 gtacaaattt attatttttt ttaggggctg tgacaaaagt cgtgtcacag tccctttttc
     5701 cgaataaacg gtgttcaatc agctgtcctt cggtattagc tcaaaaaacg gcaaaatatg
     5761 agaagctatt tttccgtttt gtatctctaa tactcaggtc aaaccgctga ttttacaacc
     5821 tcttccttaa acggtgttct cctgccaact cctcggtcac aagtcacaat agtcaacaaa
     5881 cctgagaagc tgttttttga aattgctcct tgtgactcgg agttaaacgg caggctcaca
     5941 acctcttggt aaacggtgtt caaaagccag tttctcggta ttaagccaaa tttatgcaaa
     6001 aatgtagaaa gccattttca caaaattttt cttactactc gaaactaagc gactttttca
     6061 caacctcttc cttaaacggt gttcaaaagc ttgcatctgc ggtaataagc ccaaccaaac
     6121 gaaaaatagg aggagctatt tttgtttggc tgttcttatt acttgatgca gaacagcttt
     6181 ttcacaacct ctttttataa gagtttttac tcattaattt acaaaaaaca agcaaaatgc
     6241 gaattttctc acattttttt taacaaaatc aaagttattg cttgaaagaa gaagaatcca
     6301 tcgttaaaat aaagcttgac gtagagggga gcaagaaata tgaaagattt tcaattgggg
     6361 gctgccacct atttaaaaag tgtagccatt cgggtgaaag accgagataa aatgattgat
     6421 ttttacaaga acgttgttgg ctttgatttg aaaagagaag aaaacgaatt agccatttta
     6481 ggaacagaag aagctggaag tgaaatgttg ctgctggaag aaagtcctag agcgaatgat
     6541 cacatggggg tgatcaaaaa gctgaaccgt ttttcattga ttatccctag cacagaagaa
     6601 atggcagata tcctttgtcg tatccgtaaa atgaattatc caatcaaaga agctttagaa
     6661 gatcatggac gtatggggat tttgctcgta gacccagaag agaatgaatt ggaaatttac
     6721 catgaagaga ataagaacga ccaaagagaa attccagaaa caatggatca agaagcatta
     6781 ttaagaaaat ctgaagaaaa attcagtaaa ctatcaacag gttcttattt tgaaaaaatc
     6841 catttaaatg ttactaactt aacaaaagaa cgccaatttc ttaatcatgt acttggtttg
     6901 aaggtacata atgaagaaga gggcatccat gtattgaatg aaggagattt ccatgttggt
     6961 ttgacagaag ctagcggagg cgcaattgat ttgcctacag atgaagtgat tggacttgat
     7021 tttctgaaat tcatgatcga tactgaaagc atggaaggac tgattgctca cttgcagcaa
     7081 ctatcagttg atttcttctt agacaaaaag cacacagtac tcacaatcta tgatgctata
     7141 ggaatcgaat ggtggttcgt cagtgagcca aaagaaaaga ataaaactga cattcgatgc
     7201 gacgcttaac tttttctttc ttaacgattg tcgcatgtct cgtcatttta tgaacggtca
     7261 tactatcgct tattctagag atagaaagag aaaatagtat accgggggaa actgcgcggt
     7321 ttttcgcgca gtttttttgt gtaaaaaagg ttgattcctc atagattaag ctttaagctt
     7381 ggactgtaag aatctgatag aaaagcagga gaaaaagatg tatccacaca cgaaacagct
     7441 tattttgaaa aagatggaag aaggatttta tccaggtgta gcagtcgcct tcataaaaga
     7501 aaatcaagta gaaacattta cagccggctt tgcccaagtc gttcctgaaa agcagctgat
     7561 gacagaagat ctgttgtttg atgcagcctc actgacgaaa gtcgttgcaa ccacttcatt
     7621 agttttacgt ctattagaag atggaaagat agaactcgat caaccgcttc ataaatatct
     7681 tcctgaattt gaaaatcaga caatcacttt gcgtcattta ctgacacata cttctgatat
     7741 caaaacatgg ataccaaaca gagataagct atctcaggaa gaattgatcg ccgcttattt
     7801 gaagctagaa ccaggtgagc aactaggaaa agaagtaaaa tatacagatg ccggtacgat
     7861 tcttcttggg ttgatgctag aggaaattta ccaagaaact gcagtggaaa tctttcaaga
     7921 acaagtattg gaaccattag gaatgatgaa cagcttattt cttccttttc cttccaaaaa
     7981 aatcgttccc acagaacaac tgccttcggg tgaggttttg cgtggacaaa ctcatgatcc
     8041 gaaagcaaga gttttggctg aacatgcagg taacgcgggt ctctttattg atttgaaaga
     8101 cagcattact tttgtccaaa tgtatttgaa caagggaaaa atccgtaatg gtcgtttttt
     8161 agaagaagag acgattgatt ctttactgca agatcaaaca ccgaaaaaaa atggctatcg
     8221 ttctttagga tgggacttaa aaaaggatgt agaagacggt catgcgattc tttttcatac
     8281 tggttataca ggtacgtttt tcttgattga tataaaaaca caagaagcgt tgatattttt
     8341 gtcaaatcgc gtacatcctg tcgatcatcg tgcggagtat ctcatatgtc gagatgaaat
     8401 tgttgaaaac tttttgaaag agaaagcggt attaccgaaa taatgctata atagctatga
     8461 aaaatgagag gagtttgaat tatgcaggaa cctatgtttt taaaaccagt ttttcaagaa
     8521 aaaatttggg gaggaagtcg tttacgttca gtctttggtt ttgatatccc taacgataaa
     8581 atcggagaag attgggcgat cagtgcgcat cctcatggtg tcagtgtagt agaaaatggc
     8641 gaattcaaag ggaaaagatt agatgaacta tggtcagaac acaaggaatt gtttggccat
     8701 ccttcagaac cagtgtttcc attattgatc aagatcttag acgcagaaga tgatctatct
     8761 gtacaagtac atccagatga tgcctatggg atgaaacatg aaggtgaatt aggaaaaact
     8821 gaatgctggt atatcatcga tgctgaacct ggtgcagaaa tcatctatgg tcatcatgca
     8881 aagacaagag aagaactagc tgagatgatc aaagatgggc gctgggatga ccttttgaag
     8941 aaagtaccag ttaaaaaagg tgatttcttt tatgtaccaa gcggaacgat ccatgctatt
     9001 ggtaaaggaa tcatgatttt agaaacacag caaagttctg acacgactta ccgcgtgtat
     9061 gactacgaca gaaaagatgc gcaaggacaa acaagagagc tgcatatcca acaatcgatc
     9121 gatgtaacaa ctgtccctgc gaaaacacca gaattacaaa tcaaagaagt ccgaaaaggg
     9181 aattcatcga tcgtcactta tttagaaact gagtttttca atgtatatga gtgggatatt
     9241 aaaggaatca catctttcaa aaaacaagcc ccttatacat tgatgacggt aatcgaagga
     9301 gcaggagacc ttgtcgttga cggaaaaaca tatccattag aaaaaggaac aagctgtatt
     9361 attccaaatg gcgtttctga gtgggcggtc caaggtgaac tagcaatcat tgcgtctgaa
     9421 ccaggcaaat agttcccaga tagctgaaag cagcagacgg tttttcgttt gctgcttttt
     9481 ctacataaaa tccgtccatc aataaataga agtctggtga aaaagatgga atacaaatgg
     9541 aaagcaaaca acagcagtcg cgtgtctatg aaacaactga gaaaagctgg acatcactta
     9601 aatgaaatga tcatgccaaa tctaagtctg tttatcgctt ggggaatctt gtcattagca
     9661 acaaaaggtg tgtctggcga tttgcacacc acattagaag aggtatgcca ttggatgatc
     9721 cagctgcttt tacccatctt gatcagttat tcaggcggga aatcggtagg gggacaaaaa
     9781 ggggcagtcg ccggtgcaat tgcttcttta gggttgatcg ctcgttccaa tgctccacaa
     9841 atcgtaggag cgatgattat cgggccgctt gccggcatcg tatatgaaca atttgtttct
     9901 agattccatg tgaaattcaa ggctggatat gaaatgcttg tcagcaacct actagtagga
     9961 ctgactggta gcgttatttg tataattgga atcgttttta ttgaaccagt tttaaatagt
    10021 gttcacttgt tgctcgcctc cgttgtgtct tggctagtca caatgaatct gttaccactt
    10081 gtcagtctga tcttagaacc tctaaaagta ctatttttca ataatgcaat caatcatggt
    10141 gtattgacac ctttaggaat cgaattctca caaacagtcg ggtactcttc cttatttttg
    10201 atggaggcaa atcctggacc tggtttaggg atcttacttt ctatcctttg ttttgcagaa
    10261 aaacaggaaa aagtaaatgc gagtggagca ttgatgatcc atgcgattgg cgggattcac
    10321 gaaatctatt ttccatttgt cttgctgcga ccgtatctat ttttagctgt aatggctggt
    10381 ggggcaagcg gcacgttgat atttcaatgg ttagatacgg gattagctgc acctgtatcg
    10441 cctgggtcac tactcgtgat ttttgccaat gcgccttatc cacaactagc tggggtaagt
    10501 atagggatag caatcagtac atttgtgacc ttcatttgtg cagcgatact attgaaatta
    10561 ccaaataaag aaaaagagaa caaaacggtc aaagaaaggg gagaaatctt ggaaccatct
    10621 atcattcatt ccgtcatttt tgcttgcgac tcaggtatgg gatcaagtgc tatgggagcc
    10681 gccctgctga aaaagaaatt agcagcagaa aaaatcgatc tttctgtcgg atacagctct
    10741 atctatgaat tgaataacca agtaaatcag ctggttatcg tgcaacatga actagcgggt
    10801 cttgcaagag aaaaagtacc tcaaagtcaa atctatgtac tggatcactt tttggaaaca
    10861 gatatcttgc tgtcacgaat aaaagaagcg atccaatttc caaagcggga agaaaaaaaa
    10921 gagatagcag atatcacaga acaaaaaacg tcgcctgcta atattgtatt tttgtataaa
    10981 aacaacagac gcggctcaca aactatgggc atgacgattt taagtcaatt agcaaaaaaa
    11041 gcgaaaaaac agtttgttat ctcaaaagaa tcaatagaaa aaatcaaaat ccaagaagaa
    11101 acgatttata tcgcacaaag agaactagct gtaactgaac agctagaaga aaagatccct
    11161 cggctagttc tagttgaaca ttgggtagct acgaatgaat acgaaaaact cgtgaaggga
    11221 gaaatataag atgtatttat cgcccagaga aaaacaatta ttagcagaat ttctcagtag
    11281 cccgtcacct gtatctatcc aaaaaatgat gaatttattg aaggtcagta aacggactat
    11341 ttaccgcgaa ttagataatc ttgaagtctc attgaaatcg gtaaatgctt ctttgaaaaa
    11401 agcagctaga ggctcatttg tcattgaggc atcagaagaa gtattagagc aattaaaaga
    11461 aaatacagat gggaaaagta atgacttatc cactgctaaa cgacaacacg cgattttagc
    11521 cgagttgtta ctgacgacag agccgttgag tcttgctcat ttcatggaat catatcgcat
    11581 cagtaatacc actttttatg cagatatcaa acagttggaa gaaagtattc gccaactgcc
    11641 tttggaaatc attcggaacc agggatacga gatcgaagga ccggaaaaat accgccggct
    11701 tctgacagcg aatgtattag aattagaaat caatgaatat gaactttttc atagtatttc
    11761 tttcgatgca tcactgaatt atttttttcg attcgttgat ccgcaacatc tatctcttgc
    11821 acgcaaagta atcggggaag aattgatcca aaaaaagacc aatctaagtg atagaaagct
    11881 tgaacatttg gttttgatgc tgacattgac gatggagcgt gtgacgaaaa atcatttact
    11941 gacaaatgag acatataata gtctggcaaa caaagaatta ctacagacag ctaaacgatt
    12001 gttttcacgg atcgcttctg agacaaaaca actttatcca gtaaatgaga tcgtcttttt
    12061 tgcaggatta ttaaatgact tcacgaactc atttgatcag aatttctttg aagagacgtt
    12121 cgatacacag cttgcttatt tagtaaaaca actgattcaa gaagtaagtg aagagacgaa
    12181 tgtccatttt tatgaagatg aaactttgta caaaatgctg ttgactcatt tatctggtgt
    12241 gttttcaaga gccgttttac aagaagagac actgaccaat ccgattttag aaaaaatcat
    12301 ggttcaatac gaggaagttg cgaatgcaat ccgtaaagca gtagagcgga tttttcaaga
    12361 aaaaaaatta tccgaagaag agatcgctta tatggtcctt cattttgcga attcattgga
    12421 acgaagtccg aaagaaagca atatcagtat tgcaggattt tcgccaagtg gattagcttc
    12481 tactagcatg ttggaactac gattgaaaag gtattttccc ttcatccaac aaattcattt
    12541 ctatcggatt gctgatttaa aaaaaatcga tttacaagaa gaatatgatg ttgttatttc
    12601 tacatctatt ttaccaggat acggtggaaa atatatttta gtctccccgc tactgctaga
    12661 agatgaagtc aagcagctaa aagaagcttt ttcgcatatt gagaagaaaa aaaggcaaaa
    12721 aattacgtat aacagcaata acgagtggat gatagaagat acttatgagg aaacaatgca
    12781 tttcatggat caaatcaatc aattactcgg tcgttttttt atccaagaac tggataatcc
    12841 tgagacgatt tccgaaacga ttcgcagctt atttccttat tttcctgaag gactagtaac
    12901 ggatgaagag gtggttcatc gccggctgct taagcgatat gaacaagcac ctatcggtat
    12961 tcctcataca aatatggggt tattccatac atccagctca ttgatttcta aaccgatctt
    13021 ttgtattttc aatttgaaac atccgttgac cattgaaggg atggatagac agccagtcga
    13081 tttgtcccgt atgttagtta tgctggcgcc ttcgccaatc caagaaaaag acgggattct
    13141 tttaggaaag atcagtggag caatcatcat gaatgacttg aacaccgaga tcttccgctc
    13201 aggaaataaa gaaatcgttt atcagttgtt agcgaaaatc ctgattgaag aaataaagaa
    13261 atgaaggtga aaagatgata cagctaccag cagaaaaaat attgctcgat caatcctatc
    13321 aaaattggaa agaagcgttg accgagatcg gccagtggat gacccaacaa gggggaatca
    13381 aaccggcata tatccaatca atgatcgaaa gacaagaaaa agcgagtgtc tatatcggga
    13441 atttcgtagc cttgccacat gggactgaca aagatgaaga agtagtagaa gaaggaatct
    13501 atttagtcca agtgcctgat ggtgtggact ttggaacaaa agaggaacca aaaatcgcga
    13561 cactcttatt tgtagtggct ttaaaaaaag aacatcagtt agcggtgctc caagatttag
    13621 cctttttctg ttcagacatc gaccaagtaa tggcgctcag tgatgcggaa accattgaag
    13681 aagtccaaat gatttttgaa catggacata tataaccaat gttcacagta aaaaaagctg
    13741 ccttgcatca agtaataact tcaaccaaga taaaaataag aggagctatt tttgttggga
    13801 ggttcttatt actgcggatg caagcttttg aaaactattt attctagaaa accgtttatt
    13861 tgaaataggg gacggtgaca aggtttttgt caccgcccct attatttttg tgttttaata
    13921 gctctttttt atatagatag tgcccatacc tatgaataat aaaacgatac tccatatacc
    13981 aagtgtcaag ataccattca tgaaagtaac ctgttctgaa gctagtggcg agaaaatatc
    14041 tcctcctatg atcacatttt gaaaatcaac ataagaagtt ggcaagtaat gactgattga
    14101 ttctatccat ccaatcgaag aaaacaagcg atactctgct aagaaaagac aaagaagtgt
    14161 acctaaaaga ttgactagag aatgttcaaa taaagcagat agaagaaaac tgattgtact
    14221 taaaaagagc acccacaaca acaggaacag aaagctctgg aaaagatact catacatcgg
    14281 caggattcgt atctcctgac caatgatcgt tcctacagga taacggaagt ctcccaaacc
    14341 atttttgatt attactagta tagagacgat caaaaatggc atcacgagac ttagcatagc
    14401 tgcaccataa taaatggtaa aacggatgct atgtttcttt accatactat ccggtaatag
    14461 attgactaga gagattacct gctttctttt ttcataagag atgatggaag aaagaaacaa
    14521 ggcggttata cataaaatca aaaaactaga aatcattcct gaaaaaatat tttcgtagta
    14581 atttgctaaa gagagatgcg ctggcaagtc aaaaatagaa tatctttgga tctgatgttc
    14641 tttcatataa cggagcaact cgacacgttt ttgttgttca atgattggaa ttccttgtct
    14701 ttgaccagaa atcagtcgat ccagtatatc tttttcataa tgataagttg cttcgaccat
    14761 ttgctggaca ttccctgtgt tttttgcatg taagattgct tcgatcagtt tgttgctttt
    14821 ctctaaactt tccacaaatt ctttctcatt ctcatcttct ttcaacgttt caatcaaacg
    14881 ttgcatctct tcatagttat gattcagttc atcgaattct gtataagcaa gtttatgatc
    14941 aaaaaaaagt gggaatgcaa agagcacgac caacaataga ggaaataaaa agtttacttt
    15001 gttttttagt aagagattgc gttcaaatgt aagtaaagac atagttacac ctcatataat
    15061 ttacgataaa tagctaaaat ctcttccata tttgaggatt ctgtgacgat ttctccattt
    15121 tttagaaaac atgctttaga acaaatcgat tggatattcg cgatagcgtg ggaagaaaga
    15181 agaatcgtct tcccctcttt ctgccattgt ctgatgaggc tattcaagat atcaatactt
    15241 cctgggtcta atccgttcaa cggttcatcg aataacatga cagatgaatc actgatcaag
    15301 taagcagcaa gcaagacatg ttgtttcatt cctagagaca tttttccaat cggcaaagta
    15361 aggtactcag tcatcttcaa tcgttggaaa acagtttggc attctacttt gctctgccaa
    15421 tagtatttga tcaaagtcaa ataatcaaca gccgatagat agtcggataa ctgattcgtt
    15481 gattctagaa aaaagaaaga ccggcgataa tctgtataag cagtaggaga gatgttgtga
    15541 agggacaatt gatcataagt tgttggcagc agttgggcaa tgccattcag caaagttgtt
    15601 ttgccaaatc cgttcggggc aatcaaagca gctacttctc ctgattctac taaaagattc
    15661 aattgtcgaa tcacacgttt tttaccacgt ttcatgttca tgtttttgat cagtaatgtc
    15721 atagataggc ctccaatata aaatttaata acataataga atggaaaaca tctaaattaa
    15781 atgctaacaa aagttattgt ttgcatatta taaaaaaatt aaaataacag ttttatttaa
    15841 aattgaagtt ttctgatacc gaaatctttt tattttgctg acatactcaa acctttggca
    15901 caaagtttcg tgccaaagta cgactatttc tctttttagt aagcggatac aattagagta
    15961 tcaaaaggag agagggagag acaaaatgga acggacgatt cccaaaaaca acatttcgct
    16021 aaaagcgagg gtacaaaaat taggcagtac tttatcaagc atggtcatgc caaatattgg
    16081 agcactgatt gcctggggtg tattaacggc tctatttatc ccagatggtt atttaccaaa
    16141 tgaggctttc gctaccatgg taagcccaat gctaacttat ctgattcctt tattgatcgg
    16201 ttatactggc ggaaaagtaa ttgctggtga ccgcggatca gttgttgggg caattgcaac
    16261 gatgggtgtg attgtcggaa cagatattcc aatgatgcta ggcgcgatga tcatgggacc
    16321 tcttggtgga tatgccatca agaaatttga tcagctattc caaaaacgga tcaaatccgg
    16381 ttttgaaatg ctagtcaata atttttcagc aggtcttatc ggttttggat tagcgttatt
    16441 aggtttttct gcgattggtc cagttgtcga tgcattgact caagcaatgg caaaaggtgt
    16501 agagatcatt ttatctgccc atttgattcc attgacaagt atttttattg aaccagcaaa
    16561 aatcttattt ttgaataatg caatcaatca tgggattttg acaccattgg gaactgaaca
    16621 agtagcagag gctggaaaat ctattctatt cttgcttgaa gcaaatcctg gtccaggact
    16681 tggcgtatta cttgctttta ctttgtttgg caaaggagca gcaaaatctt cagcaccagg
    16741 agccatgatc attcactttt taggcgggat ccatgaaatc tattttcctt acgttatgat
    16801 gaaaccgtta ttattcttat cagttatagg cggaggaatg tcaggaagtt tcattttcca
    16861 attgatggat gctggactaa gagcgccagc ttctccaggg tcgatcattg cgattctagc
    16921 gatgacaccg ttcaattctt accttcctgt tattttgggc gtgattgttg ccgcagctgt
    16981 ttcgtttggt atttctgcag taattttgaa agcggatgcg aaagatacaa atgaagactt
    17041 cgaaaaatct gttcaagaga caaaggcagc taagcaagct tccaaaggtg cccaaggtat
    17101 tcctcaagga gctacattct ctggcgtaca aaaaatcatt tttgcttgtg atgcaggaat
    17161 gggatcaagt gcgatgggcg cttcgatctt gagaaaaaaa gtacaggaag cagacttgcc
    17221 tcaaacggtg accaatcaag caatcagcca actgacagat gactcgaata cattgatcgt
    17281 tactcaggtc gaactacaag aaagagcaaa acaaaaagca ccgagcgcgc gttttgtctc
    17341 agtagaaaac tttttgaatt cacctcgata tgatgaaatc attcaagaat taagcagcaa
    17401 gcagaaaaca tcagtttctg aaattgagaa tgagccagca gaagagtttc tttcagcaaa
    17461 catcaaacaa atcaaagaga ttctacttgt ccacgatgat cgttccggat cagcaacaat
    17521 ggggatgacc gtgctcaaag atatattaga caagaaccat ttaactatcc cgttaagaaa
    17581 agtcaatatc caagatttaa aagatgaacc tgattcactg atcgtagcca aagaaagttt
    17641 agcggaaaaa gtacagatgg ctgcacctca atccattcat ttatcagtca acagcatggt
    17701 caatccgcaa aaatacgaat cgattgcaca atatttgaaa cagacagctt aagggaggaa
    17761 aacagcatgc aaagtttgcc attcgacatg atcgagctca atcgatcttt taaaaccaaa
    17821 gaagaagcga tccgctattg cggtcagatg cttgtagaag cagggtgcgt tgatgaggaa
    17881 tatatcgatg ccatggtaga tagagacaaa atgttatctg tttatatggg gaattttatc
    17941 gcgattcctc atggaacaga tgaagcaaaa aaatatgtga aaaaatccgg catctgtgtc
    18001 gttcaagtac cagatggtgt agattttggt accgaagaag aagaaaagat tgcgactgtt
    18061 ttgttcggta ttgcaggagt cggagatgag catttgcaac ttgtacagca aatcgcactt
    18121 tattgcagtg atatggacaa tgttgtccag ctagcagacg cgctcagcaa agaagaagta
    18181 acggaaaatc tagcaattgc ttaaggagag agaaaaatga gagcagtaca ttttggtgca
    18241 ggaaatatcg gtcgaggatt tattggagag gttttggcag ctaatggatt tgagattact
    18301 ttcgtagatg tgaatcacac gatcattgat gctttaaatg aaagaaaaga atacgaaatc
    18361 gaattagcag atgaatcaaa agaaaaaatc actgtaaaaa atgtcaaagg aatcaacaat
    18421 caaacaaatc cagaaaaagt aatccaagaa atcgctgaag cagatttagt tactaccgcc
    18481 attggcccga atatcttacc ttttattgct gagttgattg caaaaggtat ccaagaaaga
    18541 gaaaaggaag gaagcacaac atctttagat atcattgcct gtgaaaatat gattggcggt
    18601 tcagcatttc tagaaaaaga agtgtataaa tatcttccgg aaacatcatt tactgacaaa
    18661 tatatcggct ttccaaatgc agcagtcgat cgaatcgtcc cattacaaca ccatgaagat
    18721 cctttattcg tccaagtgga acctttcaaa gaatgggtca ttgacgatag ccaaagaaaa
    18781 aataaaaaaa tccaattaaa aggggtttta tatgtagatg atctagaacc atatatcgaa
    18841 cgcaaactat ttagtgtcaa tactggtcat gcgactgtcg cttatacagg tgccttgtta
    18901 ggttaccaga ccattgatga agcaatgcaa gatgcgttag ttgtggcaca attaaaatca
    18961 gttttgcagg aaacaggaag tttgctgatt gccaaatggg ggtttgatgc agagcagcat
    19021 catgcgtata ttgaaaaaat cattcatcgc ttccaaaaca aaaatatctc tgatgcgatc
    19081 acacgtgtcg ctcggacacc attacgtaag ttaggttatc aagaaagatt tacacgtcca
    19141 gtgagagaac tacaagaaca taacttgact tgcccacatt tgacggcaac aatggggatt
    19201 atttttaatt actatgatcc tgaagatgaa caaagccgtc aattgcatga aatgaagatc
    19261 catgaaaact tggaacaatt gattcaagaa gtcacaggaa tcaatgatcc gaaaacaatc
    19321 gggaatatca agcaaaacgt gaaccgttat gccaagcaag tcgcttaaaa taggatacga
    19381 aaaaggggaa tgtgacgaaa tttttgtcac attccccttt ttcgaataac taggctgttt
    19441 gtccttcaag atagggcaga tccaattctt taccgtaacg ttgttctaaa gctaggcgga
    19501 tcaaacgagc tgccaggttc tcatttcttg caaggatagg tccatggaaa taagaaccga
    19561 agacatttcg gtaaatgaca ccttcagatt ggtcttcacc attatttcct tgaccttgta
    19621 ccactttccc caaaggtcgt tcaccttcac ctaagaaagt ccgaccattg tggttttcaa
    19681 atccataata agtttcattg aattcttcgt tatggataac gatatcaccg ataaaccggt
    19741 tattttcctg acttaacgtg tagtgatcca gtgcactgat tccttggatc ttttctccat
    19801 tagctcccat gtagtagtga cctagcaatt ggtagccacc acaaatggct aacatgacgc
    19861 catcattttc gatatagttg atcaaagaat ctttcttttt ctggatgtct tttgaaatga
    19921 ttaattgctc aaagtcttga ccaccgccaa agaaaaccaa gtcatattta tcagcatcaa
    19981 aaggttcatg tatactaacg atctccgtat ggcaagaaac ccccattttt tctgctatat
    20041 atttcaacat caaaaggttt ccgttatcac catatgtgtt catcaaattt ccataaaggt
    20101 gggcgatatt gagttcataa ttagccacgg ttcattcctc ctttgataaa tccttgagca
    20161 gctagttctt tacgaagctg caatacagca gtgtaagtag ctaaaatata gacatgctca
    20221 gttggcaatt ctttgatttt ttcgattact tctggtaatt cttttgtttc tgtcaattta
    20281 ttttctggaa tcccggcaac ttttagacgt aaagtcatat ctgtatgacg gtctcctcca
    20341 gaaataacag ctgggatatc catatcggca aagttttcaa aattaccatc ccaaatccag
    20401 ctgacatcga ttccgtctgc gtaattggca tttaataaag ccactaaaga aaatggataa
    20461 ggagctagac caatcatatc gattacttga ttgataccta caggattttt gacaagtact
    20521 aatgtacatt ttttcccatt gatattgatg acttcttgtc ggccgaatac tttctcgtca
    20581 tatcctaaac cttgtttgat tttatcagga tcgacattga agtactctgc cactgcagta
    20641 gctgctaaag cattgtagac attatacata ccgccaactt cgattccgta ttcatgacca
    20701 tcgatcacga aatctgctga cacattgtcc atccgtacca tatcagttaa tcgataatcc
    20761 aattcaggac gtttgaagtc acaatttgga cagtaatatt tccctaagtt tgcataagtg
    20821 atcattttat aatgcaagat gtgatgacaa tttggacata agacaccgtc tgtattgtaa
    20881 tgagccattt gttcacgatc ttcttcatgg tcaaagccat aatattttct aggattgact
    20941 gtttcgatag aattgaagat tggtgaatca ccgttactga taatcgttgc atttggtgac
    21001 tttgcggcac cgtctacaat cattttatag gtcgtataga tttctccata ccgatccatt
    21061 tgatcacgga aaatatttgt aaataagaac agttctggtt tcatatattc tgtgactttg
    21121 ctcaaacttg cttcatctat ttctaggaca gcaaactttt tctgtccttt ttttggtttt
    21181 gcctgcaaga aagtcgatac aattccctgt accatattcg caccagtagg gttggttaga
    21241 acttcatcga attgctggcg caaaatattg actgttaaag cggtagtcaa tgttttaccg
    21301 tttgttccgg tgacaacgac gacttggtag tcttttgcca aactatctag tatatgtgga
    21361 tcgactttca gcgctagttt acctggtaaa cttgatccgc ctttaaaaaa agtttttaat
    21421 gcccattgcg acgtttttcc aactgcaatc gcaaaatgac tgcgtattcc cattatgtaa
    21481 cctccaaaaa cgatttgctg acgaataaat tcaactaatc ataccatatg ttgaaaaaaa
    21541 ggttaaattg cttttcttat tcttaagaaa aggttacggc tgaaagtgca tgaaatcgga
    21601 caaaatcgca tgatttaaca aaaaaacagc ttgaaacaaa atgattgttt caagctgctg
    21661 tgattttatt attccctctt acctatattc ccattttaac cgataataat tttctcgctt
    21721 ggatattcat agcctagatc tcgtgtttct tttggcacga ataacatcaa tgtatatagc
    21781 attccgatcc gcccaataaa catcagtgta gcaatcgtga ttttgcccac aacagacaag
    21841 tctccggtaa tccctaaaga taaaccagtt gttccaaacg cagaagttac ttcgatgatg
    21901 atcgagatca gcgtttgttc ttctgtagca gataaaaaaa cgatacaaaa gaaacacata
    21961 ccaagagaaa gcataaagac aacgactgat tttcgcacat catcttgatc gattctccgt
    22021 ccaaaaatat tgatgttatc ttcacttttg aggaaggaat atagatacaa accgatgatt
    22081 gctacagtag ttgttcgaat cccgccgcct acagaactag gactgcatcc gataaacatc
    22141 agtaaagaaa aaatgatcag tgttgtgatt tgaaaatcac ccaaatcgtg aatctgcaga
    22201 ccagcattac gagtcgtaat cgaataaaac atcgaattga tccatttgac actcatattg
    22261 gaatcttgga ataaatggtc cttttccaat agataaatca agacagttcc cgaaacaaac
    22321 aagataacaa aagctaacac agctaatttg gtaaacaagg aaaaacgaaa cggaagcttc
    22381 gcattggaac gtttgtataa tagccattcc cggcactcca tcaatacagg aaaaccaatt
    22441 cctccgacaa aaatcaaaaa catgatcagg atcaagaaaa aatagtcatg tgcaaagggc
    22501 ttgatggaat ccccagtgac gtcaaaccca gagttcgtga cagccgatat cgcctgataa
    22561 aaaccgtaaa aaacggcatc acgccaacga tcaaaatagc ctctgtaata aaaataaata
    22621 gaaaagaatg tcccaaaaag taattgaaac cagattaaaa tagcaaaagt gatccgaatc
    22681 agtcggacga taccagacaa acgcggttga ttcatatccg tcatgatcag ctgtcgctgt
    22741 ttcagtgtga tccgtcgttt agaaaaaatg acaaaagcag tagaaatcat catgatcccc
    22801 aaaccaccaa cttgaaataa tatttccagc agtataatac cgttatcatt gaacacagaa
    22861 ttgatatcaa aagtcgatag tccagtcaca ctcactgtac tgattgccat gaacagcatg
    22921 tccacaaaag aaacatggct atctggttcg cgaaaaatcg gcatataaaa tagaacgagt
    22981 gataagaccg tcatcaatat ataataaaaa acgatgattt ggatcgatga gaaatgattg
    23041 gcagcaaact tctgtcctcg ccgctgcagc cttcgaaaga ataaatcaac atgcacagta
    23101 ctatcctcct gacaatagtc gtttctacca gtatacaagg ggaattagga atactcaaag
    23161 aaattatcaa acagataaca atacagcttt cgattaaaat agaaatggct tataataagg
    23221 aaaatcctag aaaaaagaag gaggaggaat aacaaattga ttaatgctca acaaatcgta
    23281 gaaaaaatga aaaatcaaaa aataaattat gatacagttc tgaaaaaaat gatcatgcaa
    23341 tgggagaaag aagaagtaaa gcctaagata ttaatacata catgctgtgc tccttgcagt
    23401 acgcacacat tggaattcat gtctcaatat gcagagatca cgttattttt ttcaaattcg
    23461 aatattcatc ctaaaagtga gtatttgcga agattacatg aacaaaaacg atttgtagac
    23521 caatttaatg agaaaactga ccatcatgtt gcgctaatcg ttgatgaata ccgtccaaat
    23581 gaattcacca aaatggtttt aacaaaccat cttgaaaacg aaaaagaagg tggtgctcgc
    23641 tgcagtgcat gcttcaatat gcgattagat cttgttgcgc aaaaagcgca agaactagga
    23701 tacgattact ttggaagtgc cctgaccatc tcgccaaaga aaaatgcagc tttgatcaat
    23761 cagatcggaa tggatatcca aaagatttac gggacacaat acttgccaag tgatttcaag
    23821 aaaaacaaag gctatgaacg ctctttgcaa atgtgcaaag agtatgatat ttatcgccaa
    23881 tgttattgtg gttgcgtgtt cgctgccaag cagcaaggat gcgatctgaa agaaatcaat
    23941 cgggaagcaa aagcttactt aaaaacatca accgtagttt ttgaggaaaa ttaaagaaat
    24001 ctttcggaaa aacgtaagaa aaaaataaag aatttatggt agaaataagg tagactgtat
    24061 aatttgtccg tagtaaagta aggaaacaag aataaatttc aatgaaggaa gagataagat
    24121 gcgaaaagta gcacctattt tgaagccaat cgctgtatta acaatctcga cgattgtcgc
    24181 gactactaca ggtattgtga atagttccag ctaccgtgca ccaagttcaa gttctagtac
    24241 tgtagaagaa acaacaccaa ctacttcagt ctcgacatct gaaccaacaa caacggaaag
    24301 tttgaatgaa accactacga caagtacatg ggacgataca acaactagtt cgtcgtatga
    24361 tgagacatat acaactgaca gctcaagcga aacaagtaat acggtaccag atggcactcc
    24421 atcggattca accaatccaa gtacaagtcc ggatacaagt gctagctccg aaacgatacc
    24481 aagcagtacg actgtagatg ataacacgca aaatgatgat gcagcacgta cagcacagca
    24541 aaaccaagat tcaggaaata cccaaacgta taaccagcaa gcaggtgatt ctcaatgaca
    24601 tttttactag accttatcaa cggggtgcat aaattccttg gctatttaga catcagtcct
    24661 aaatatctta accgtggata tacgatttta agtgtgattc ccacgcttta tttattgaga
    24721 attgtttatg gactttggca aaaccaaaac tatcttcaat ttttcttata tggacttgca
    24781 tttctagtgc ttgtttattt tactgtttta aatgtatttt attacttttt agataaaaac
    24841 acgaaagccg atgtcactca gctttttgtg aagtatttac ctgatgaagc gttcaacatc
    24901 cagacagaag aatcgataga taatggaaat tcgatcgata aagtgaatac acaagaggtc
    24961 atggtttctt atgacgaaga ttatcaattg aaattagccg agaatatgcg gtatttgatt
    25021 ggaaatggtg agatcaaaac aaatgaactc ggtcgcatgg atggatttct ggtcgataga
    25081 aatacattgt atccttatta ctatgtcaag aaaacaggag agaaagagta tgttctaaat
    25141 attggacgaa gctactcgga catggaaaaa gtagggacca ttcgacttga ctcaacagaa
    25201 gacacattgg aacctgtcgg attgttcatc gtcggcggtg attttgtcaa agacgggtta
    25261 cgctatcatg agccttatcg tctgaaattg attgcaaaaa aggcacagtc gcaggaagaa
    25321 ccagtggttt atagtcgtag ccaaagaaga agacattcat aatgtgatga aacgccgtgt
    25381 atcagtggtt gcgataaaaa cgtttattcg gaataagggg gatgtgacac gtcttttgtc
    25441 acgttccttt tttatataac gagaaagata agacgaacac atcacttatt ctttcctttc
    25501 atttataaac attgtagaat aaagaaagta caacgaagta ttgtgaaaaa acgtaataaa
    25561 taacgaggaa aatacaagta ggaggtaagc tgtgaaagaa tttttgaaaa attgggggat
    25621 tttgatcctt gtattagcgg ctattttatt agctagagtg tacgtgttta caccagttac
    25681 tgtaaacggg cattcgatgg accctacatt aagtgatgga caacgattga tttcatctaa
    25741 gatctcaaac tatgaacgaa tggatattat tactacaaag gaaccggggg atgaagaacg
    25801 gatgattgtt aaacggatca tcggtatgcc tggagataca gtcaagatgg aaaatgacca
    25861 gttgaccatt aatggcaaaa agtatgatga accttatctg gatgagttca aaaaagaatt
    25921 ttcagaagat aagttacaag gagaatatgc ttatagctca ggattccaag cacaagcaga
    25981 aagttcatcc acctttacga gtgactttga atatactgtg ccaaaaggaa agtatcttgt
    26041 tctaggcgat aaccgcttga tttcaaaaga cagccgaatg tttgggttag tcgacaaaga
    26101 tatgatccaa ggaaaagttg ttttccgtta ttggcctctt tcagaaatta aaatcatgtg
    26161 atgaaaaaat aaaaagaagc tgtgacatgt tttttgtcac agcttctttt tccgaaaatt
    26221 ccttcttatt tcttggagtt gctcactttt tttgcaatct cattttaagc tttttggctg
    26281 atggataaga aaagcgaagc gtttttgttc ataaatagct tttccccacg atggaaggta
    26341 tgactagtag cagagacaaa gcccgttttt tccaatcgat tattcaattc ttcttggcta
    26401 aagccattat ggactttcgg atgactaatt tgttcattct tgtcaaagtc tacgatgatc
    26461 aattgaccgc caggagctaa aatttcataa agttttgtaa gaatattctc cgtatcagga
    26521 atgtgtaaaa gtacaagtga tagaaggatg agattagctt ggacagcagg aaattcgaca
    26581 gaagcatcag cgtggatcgt tcggacattt ttcagatctg ctgcttggat cttttcttct
    26641 gccattttca gcatagtttc tgaagcatcg gcaatgatca gttctttgaa tctttccgca
    26701 agcggtaaac taacaagccc agttccgcct ccgtaatcca gcaggacttt ttggtggctg
    26761 tcgcgcggta gataagtagt tagttcttcg cgaataatct tggctaatgc ttgacggtca
    26821 ggggaatcat aatggttagc gatggaatca aaaatatttt ttgtcatcaa atagctcctt
    26881 acgtaaaact ttgaaatttt aacttattat agcacgtgaa aagaaagaaa gcatgctata
    26941 ctcaattcaa aaagggagaa tctagaaaga atatgccgat atcgtttgta aaagatagag
    27001 aggaaaaagg aaagtgtgtc cgagaaatat tactagactt gcctgagtgg tttgggcttc
    27061 ctgaatcaac ggaaaaatat atcgaggaat caagtaaact acctttatgg tgtgaaaaaa
    27121 gaaaagaaga atatttaggc tttatcactc tttcacagac aagtgaagat actgccgaaa
    27181 tctattctat tgtatgggaa taaaaaaaga ctatcatcac caaggattag gaacaaaact
    27241 ttttaaagaa gcagaaggtt acgcagcaaa acattacaaa tatttgcaag tgaagactgt
    27301 agacgagggg cactactcta tatatgatca aactatttgt ttctacgaat cattaggatt
    27361 ttcaaggttg gaagtttttc caaatttatg ggatgaatgg aacccatgtt tagttcttgt
    27421 caaaaaattg gaacaaaagt gagcaataga tttaatacta atctgtgctt gatgaaaatt
    27481 ctcactgtaa aaaatgctga aaatcaagta taataccata ggaacaaact ggaaggtgaa
    27541 aaagagcatg gcacaactat tttttaagta tggcgcaatg aatagcggca agacgatcga
    27601 gatcctaaaa gtcgcacata attatgaaga acaaaataag ccagttgtct taatgacaag
    27661 cggtattgat acaagagatg gtttaggcgt tgtttcaagc cgaatcggac tgaaacgtaa
    27721 tgcgatgccg atatttgaag aaacagacgt atttgacgta attcagaaaa tggaaagcaa
    27781 accctattgt gtgctgatcg atgaagcgca attcttaaaa aagaaacatg tcattgcttt
    27841 tacgagaatt gtggacgaat tggatattcc ggttatggca tttggtttga aaaatgattt
    27901 tcgaaacgag ttatttgaag gatcaaaata tttattgctt tatgcagaca aaatcgaaga
    27961 aatgaaaaca atctgttggt tctgccacaa aaaagcaatc atgaatttac attatattga
    28021 tggaaaccct gtttatgaag gcgatcaagt gcaaattggc ggaaatgaag cttattaccc
    28081 cgtttgtcga aaacattact ttcacccatc aatgattaca gaaggagaat aagcatgtac
    28141 gatcaattac aagcaattga agaccgttat gaagagcttg gagaactttt aagtgaccca
    28201 gaagtgattt ctgatacaaa gcgttttatg cagctttcaa aagaagaagc aaacacgcgc
    28261 gaaacagtcg aagtttatcg tcgttataaa gaagtagtac aaggaatcac cgatacagaa
    28321 gaactgcttg gtgaaaaact ggatgatgaa atggctgaac tagcaaaaga agaattatct
    28381 gaattaaaaa aagaaaaaga agtcttagaa gaaaaaatca agatcttgct tttaccaaaa
    28441 gatccaaatg acgataaaaa tatcatcatg gaaatccgtg gagcagcagg cggagacgaa
    28501 gcagcattat tcgctggcga tcttttcaat atgtaccaaa agtatgctga agcacaaggc
    28561 tggaaaacag aagtgatgga agctaacgtt accggaatcg gtggatataa agaagtgatc
    28621 atgatgatca ccggagacaa cgtatattcg aaattaaaat atgaaagtgg tgcgcaccgc
    28681 gtccagcgtg ttccttcaac tgaatcgcaa gggcgtatcc atacttccac cgcaacagtt
    28741 gtcgtgatgc cagaagctga agaagtagag atcgatattg aagacaaaga tatccgtaca
    28801 gatatctatc atgcttcagg tgctggcgga cagcacgtca ataaaacagc atctgctgta
    28861 cgtttgactc acttaccaac agggatcgtt gttgctatgc aagatgaacg ttctcaaatc
    28921 aagaaccgtg aaaaagcaat gaaaatcttg cgtgctcgtg tgtacgataa gatccagcaa
    28981 gaagcacaaa gcgagtatga tgccaatcga aaatcagcag tcggaactgg ggatcgttca
    29041 gaacggatcc ggacgtataa tttcccgcaa aatcgtgtga ctgatcatcg tatcggatta
    29101 actatccaaa aattagatca gattttagca gggaaattag atgagatcgt tgatgcattg
    29161 atcatgtatg atcaaacatc aaaactggaa gctatgcaaa atgggtaaaa tgacctatcg
    29221 agaagtcctg tcacgggctt cttctttttt agaggatcat gggaaagaag catatagtat
    29281 ccaattttta tttttggaac gaaaacaatg gaaaaaactt gattggctcc ttcatatgaa
    29341 cgaagagatt tcagaagaag aacagcggtt gatcgaaacc gatctgcgac ttctgcttgc
    29401 agatcatcca cctcagtatt tgctaggata tgcagatttt tatgatcatc ggttaaaggt
    29461 aactgaagca acactgatcc ctcgaccaga aacagaggag ttagtcgaat ggtgtttaga
    29521 cgagacgcct ggtgtaccgt tagaagtgat agatattggg acagggactg gagcaattgc
    29581 tattagtttg aaagcagcaa gaaaaaattg gcatatatct gctgtggatc tttcagaaga
    29641 agcattagaa gtagcgaaag aaaatgctca gaaagaagga acgaaaatca gtttttatca
    29701 tggagataca ttaggaccag taatggatca gcaatttgat gtgattattt ctaatccgcc
    29761 gtacatcagt cggaatgaat gggaactgat ggatgaaagt gtccggtcat tcgaacctaa
    29821 aatggccctt tttgctgaga acgatggatt agctatttat gaaaaaatag cagttgaagc
    29881 accaagcgta ctaaaatcaa atggaaagat ttttttagaa atcggatttc gccaaggtga
    29941 agcagtaaaa aaaatatttc agcaagcatt tccagataaa aaagtggcga taaaaaagga
    30001 tctttttggc aatgaacgaa tgatccaagt ttatggttga agttgtggat gaaaaatttt
    30061 ttatttgttt ttttattata aaaaaacact tatttgacaa ggatgtaaac gactttttgg
    30121 tttatcaaca agtttatcca ctattgacaa atagattatc cacaaacagt ggaaaacttg
    30181 aggataaact cagacaaaat aagaatgtat gaaaaagggg ttgtggataa actgtggaaa
    30241 cgaaacgata tgatgaaaca gaattgcaag aggcagccga agcactgaaa gaaggagaac
    30301 ttgttgcttt tcctaccgaa acagtatacg gattgggcgc caacgctctt ttaccaaacg
    30361 ctgtcaagaa agtgttttct gtaaaaggga gaccgcaaga taatccatta atcgtccatg
    30421 tcgcctcttt tgaacaagta aaagagtatg tggacaactt tcatccggca gcagagaaga
    30481 ttgtgaagaa cttctggcct ggaccattaa ctttgatatt taagatcaaa aaagacactt
    30541 tgccctcagt tgtgacggga ggattatcca cagctgcatt tcgtataccg gataacaaaa
    30601 aaacactaga agtaatcgaa ctttccggtg ttccgcttgt cggtccaagt gcaaatacgt
    30661 cgggaaaacc aagtccaacg actgcagatc atgtatatca tgatctacaa ggaaaaatta
    30721 ccgggattat tgatgatgga gctacgcgaa ttggtgtaga atccactgtt cttgatttaa
    30781 gtgatccaac agccatgcct atgattttac gaccaggtgc agtaacgaaa gaacaaatcg
    30841 aagcagtcat cgaatctcct gttgctattg atcagcatct tgtaaaagaa aatgaaacac
    30901 caaaagcccc tgggatgaaa tacaaacact actcacccga tacacgtgtt ctgatggtca
    30961 gagatggcga ttggtcaact gcagttcaat gggcaaaaaa taagaagatc cgtgcaggtg
    31021 tcatagcaag ccccgaaatt gcggatcaag tgcggacaga tactgcagct gtttatatgt
    31081 ataacgacaa ctcagtagaa gcggcggcta aaggattgtt tgcaggtcta agaggattag
    31141 atgaaccaac acttggatta gatttgattt ttgtacaagt gtatccagaa actggattgg
    31201 ggaatgctta catgaatcgc ttgaaaaaag cagcaggaca aaattatttt gaaaaatgat
    31261 caattggtta ttgtcgcatt cttttagtat gatacaatgc tatcaagtaa atcttctatc
    31321 agtgaacgaa aaactaagcg taactaatcg taatagaaga gatacgaata tttggcaatt
    31381 tgtttttgat gggaaaaata aaattgtagg aaaataaaat tgtaggaaaa taaaaaggag
    31441 ctgttgtttg tggtagatta caaaacgttt gaccctgatc tttgggctgc gatcgccaaa
    31501 gaagaagaaa gacaagaaca taatttggag ctgattgcct ctgaaaactt tgtctccgaa
    31561 gcagtgatgg ctgcacaagg aagtatcttg acaaataaat acgcagaagg ttatccaggg
    31621 catcgctatt atggtgggtg tgaatttgtc gatatcgttg aaaatttagc gattgaccgt
    31681 gcaaaagaat tattcggagc gaaatttgcg aacgtccagc ctcactccgg ctctcaagcc
    31741 aacacggctg cttatctcgc tttggtagaa ccaggggaca cgatcttagg aatggatctt
    31801 tccgcaggcg gacatctaac acatggatca ccagtcaact tcagtggcaa aacctatcac
    31861 tttgttgctt acggtgttga tccgacaaca gaagttattg attataatgt ggtacgtatt
    31921 ttagctagaa aacatcaacc aaaattgatc gtagcaggtg ccagtgctta cggacgaacg
    31981 atcgactttg cgaaattcag agaaatcgca gatgaagtag gcgcaaaact gatggtagat
    32041 atggcacata tcgcaggatt agtagcagca ggacttcatc ctaatccagt tccttatgca
    32101 gatatcacaa cgactaccac tcataaaaca ttgcgtggcc ctcgaggcgg catgattttg
    32161 acaaacgatg aagcattagc aaaaaaaata aatagtgcgg tatttcctgg tattcaaggc
    32221 ggccctctag agcatgtgat tgcgggtaaa gcagtagcat tcaaagaagc attagatcct
    32281 gcatttaaag aatatagtga acaaatcatc gccaatgcaa aagcaatggt caaagttttc
    32341 aatcaagcaa ttggaaccag agtcatttca ggggcgacag ataatcatct gatgttgatc
    32401 gatgttcgcg agttaggtat aaatggaaaa gaagcagaga gcattttgga cagtgtgaat
    32461 atcactgtaa ataaaaactc gattcctttt gaaacactaa gtccattcaa aacaagcggt
    32521 attcgaatcg gcacgccagc aatcactact cgcgggttca aagaagaaga tgctgtaaaa
    32581 gtggctgaac tagttgtcaa agcattacaa gcaaaagatg ataacgctca actagacgaa
    32641 gtcaaaacag gtgtacgcga attaactgaa aaatttccgt tgcataaaaa ataaaaattt
    32701 aaattccatt agtaaacaga aaagttcaat gttgggcttt tctgtttatt ttttgggaaa
    32761 acggattctt tgacaatatc ggtgatgctc tctagtatat gaggtgtaat tttagtcttc
    32821 acactaaatc tcagggagga aaagtcatga ctgatcgtat ctcgttagaa aaggaagcag
    32881 tagcattcag tgatgcaaat gcgcctcatc cgcgtatcta tgaactagca ccggaagaag
    32941 gaagagtttt actagaagaa gtacaagaat cacctgtgaa caaatattcc gtcgatattg
    33001 aagacttgat ggtggatact ggcgaatggg gaaaactcaa tattcgtctc gtacgaccag
    33061 aagggaatat ggataaatta ccagttattt tttatattca tggagcaggc tgggtttttg
    33121 gcagtgctca aacccatgat aaattgatca gagaacttgc ggttcgtacg aattccgtcg
    33181 ttgtctttcc agaatatagt cgatcaccag aagcaaaata tccaacagca attgaacaaa
    33241 attatgctgt gttgcaacag ctgaataaat tagccaagtc aaaaaatctg gatctcgaga
    33301 atctaatcgt tgcaggagat tcagtaggtg gtaacatggc tacagtcatg acgatcttaa
    33361 caaaagaacg aaagggcctc ccaatatcca agcaattgct gtattatcca gtcacaaacg
    33421 ctgattttga tacagattcc tatcatgaat tcggagaaaa ctattttttg acaagagaag
    33481 gaatgatgtg gttttgggac caatatacga cgaatgaaga agagcgtgct gaaatcacag
    33541 cttcgccttt gagagcaaat ataaatgaac taaatgatct tccttcagca atgattttaa
    33601 cgggagaagc ggatgtatta agagatgaag gtgaggctta tgcgcgcaaa cttcgtgatg
    33661 caggggttcc tgttacacaa gtacgcttcc aaggaatcat ccatgatttt gtcatggtaa
    33721 atgctatgga tcagacaaag gcaacgcgtg cagcaatggc attatctact tcttggatca
    33781 agaaaaaaga ataagctttg cttgtccgca ggaaaacttc ttttcaaaaa cggattttct
    33841 taggaaaaat ggcgagtttg actagtcaat cacttgattt tgttttacaa ttaaaaagaa
    33901 acgacagaac aaaggagagc ttaaaaaatg ggcaaatttc aagtgatcga tcatccattg
    33961 attcaacaca aactaactat tattcgggac aaaaactgcg gaacaaaggt ttttcgtgaa
    34021 gtagtcgatg aaatcgctat gttgatggca tatgaagtat cacgggatat gccattggaa
    34081 gacatcgtga tcgaaacacc gatcactgaa acaacacaaa aaacgttgtc tggtaaaaaa
    34141 gtagcgatta ttccaatctt gcgcgcaggt attggaatgg ttgacggtat cttggaattg
    34201 attccagctg ctaaagtggg acatatcggt ctttatcgag atgaagaaac attggaacca
    34261 catgaatatt tcgtcaaact tccagaagac attgatgcac gtcagttgtt tgtagtagat
    34321 ccaatgttgg caacaggcgg atcagcaatc atggcaatcg atgcattgaa agaacgtggc
    34381 gcgtcgaaca ttaaatttgt ttgtttggta gcagcacctg agggagtaaa agctttgcaa
    34441 gaagcgcatc ctgatattga catctataca gcttctctag atgaaaaatt gaatgaacat
    34501 ggttatatcg ttcctggact aggggatgcg ggtgaccgtt tgtttggtac aaaataagta
    34561 aatacgaaaa agggtgtgac acaacttttg tcacatcctt ttttggtcat ttttaacgtt
    34621 tgatgcagaa cagctttttc acagctttcg tttgcatata aaaaaaccat cccaaaaatg
    34681 cagagatggt caaattcaaa tcttttttag ttctttgtag ttaacgatta ctacaccctt
    34741 actttgcgtc atcaagttcg cattttctgc agtttcatca atctcaacaa cagcggaatt
    34801 tttcaattgc tttgaaatcg ttccagtttg cgacttgccg tgaattgtga acattacgtg
    34861 agtattgatc ttgaattttt caccaatttc cgatggtacg atagttgtat caaattttcc
    34921 aaaagttgcc attttcataa aacctgcctt tcacatcaat tataccacgt tttatgaaaa
    34981 atatcatgaa attaaactaa ttttccatcg gactctttac aatcagccaa atagagtata
    35041 taatttcttt tggataaggc cagcttagct cagttggtag agcaacgcac tcgtaacgcg
    35101 taggtcgtag gttcgatccc tatagctggc attaaaagag aagacagata tatcaaggat
    35161 ttttaatcca ttgatacatc tgtctttttg tttaaaggaa ataaagtatg ctttcttagc
    35221 aatagagcat gtattatttc tataaaaatt taggagaata aaacgactag caatatagct
    35281 gtgaaatcaa atatcacatg aactgcccaa cttgtaatga tcgagttgct tttaatggca
    35341 gcttggttga ataacaatct tgccacccct tgtatcaaaa ggatgtgtgc tacagtgtgt
    35401 aaaatatttc cattatcata agtactgtaa tggataaatc caaagatgat tgctgacaag
    35461 aaactagcga caggaatgct gaacttacta gaaaaaatag cgagaaaata cactgagaac
    35521 aattcttctc caagtatcat gataggcaaa ataataaata ataacgggct gaaagcctca
    35581 tttattggat tgcctgttaa accccatttc aaaatttgtt gcaaaaatac cgagactgcg
    35641 gcactgatta ctacattgat aaaaaaatat ttggctatat ttttgacagg agcgacaggt
    35701 ttcgagaaca tttttttcgt atctttttta ccaaaaacaa gtgtaaatgc tataaatcca
    35761 gtgatagtta aagaaaaaat gctaataatg gatggcgcaa atagcaaccc taacaaaccg
    35821 agtacaacga caatagtgcc caatatccct tttttaagtt ctattttttt tcctaaaatg
    35881 ttattcatga taataactcc tactattcag tttttgaaga tagagtcagt atac
//
LOCUS       DAMEEU010000022        34701 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.023, whole genome shotgun sequence.
ACCESSION   DAMEEU010000022 DAMEEU010000000
VERSION     DAMEEU010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34701)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34701)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34701
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.023"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(451..1761)
                     /locus_tag="PB779_001104"
     CDS             complement(451..1761)
                     /locus_tag="PB779_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDE0738641.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1773..3191)
                     /locus_tag="PB779_001105"
     CDS             complement(1773..3191)
                     /locus_tag="PB779_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0738642.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3431..4999)
                     /locus_tag="PB779_001106"
     CDS             complement(3431..4999)
                     /locus_tag="PB779_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HDE0738643.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(5003..5413)
                     /locus_tag="PB779_001107"
     CDS             complement(5003..5413)
                     /locus_tag="PB779_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HDE0738644.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5410..6333)
                     /locus_tag="PB779_001108"
     CDS             complement(5410..6333)
                     /locus_tag="PB779_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HDE0738645.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6330..7208)
                     /locus_tag="PB779_001109"
     CDS             complement(6330..7208)
                     /locus_tag="PB779_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HDE0738646.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7195..8532)
                     /locus_tag="PB779_001110"
     CDS             complement(7195..8532)
                     /locus_tag="PB779_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HDE0738647.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8535..9638)
                     /locus_tag="PB779_001111"
     CDS             complement(8535..9638)
                     /locus_tag="PB779_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HDE0738648.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9712..11220)
                     /locus_tag="PB779_001112"
     CDS             complement(9712..11220)
                     /locus_tag="PB779_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDE0738649.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11186..11878)
                     /locus_tag="PB779_001113"
     CDS             complement(11186..11878)
                     /locus_tag="PB779_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDE0738650.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11900..12874)
                     /locus_tag="PB779_001114"
     CDS             complement(11900..12874)
                     /locus_tag="PB779_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738651.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13174..14046
                     /locus_tag="PB779_001115"
     CDS             13174..14046
                     /locus_tag="PB779_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0738652.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14504..16702)
                     /locus_tag="PB779_001116"
     CDS             complement(14504..16702)
                     /locus_tag="PB779_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738653.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEVEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16934..17926
                     /locus_tag="PB779_001117"
     CDS             16934..17926
                     /locus_tag="PB779_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0738654.1"
                     /translation="MVTIKDIAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17986..19407
                     /locus_tag="PB779_001118"
     CDS             17986..19407
                     /locus_tag="PB779_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HDE0738655.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSFPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19400..20899
                     /locus_tag="PB779_001119"
     CDS             19400..20899
                     /locus_tag="PB779_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HDE0738656.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20938..22332
                     /gene="uxaC"
                     /locus_tag="PB779_001120"
     CDS             20938..22332
                     /gene="uxaC"
                     /locus_tag="PB779_001120"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDE0738657.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22491..23174
                     /locus_tag="PB779_001121"
     CDS             22491..23174
                     /locus_tag="PB779_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HDE0738658.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23176..24012
                     /locus_tag="PB779_001122"
     CDS             23176..24012
                     /locus_tag="PB779_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDE0738659.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            24023..25777
                     /locus_tag="PB779_001123"
     CDS             24023..25777
                     /locus_tag="PB779_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738660.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(26053..26394)
                     /locus_tag="PB779_001124"
     CDS             complement(26053..26394)
                     /locus_tag="PB779_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDE0738661.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26462..28633)
                     /locus_tag="PB779_001125"
     CDS             complement(26462..28633)
                     /locus_tag="PB779_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HDE0738662.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGTTETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28802..29701
                     /locus_tag="PB779_001126"
     CDS             28802..29701
                     /locus_tag="PB779_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDE0738663.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29772..30629)
                     /locus_tag="PB779_001127"
     CDS             complement(29772..30629)
                     /locus_tag="PB779_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDE0738664.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30614..33316)
                     /locus_tag="PB779_001128"
     CDS             complement(30614..33316)
                     /locus_tag="PB779_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HDE0738665.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33329..34618)
                     /locus_tag="PB779_001129"
     CDS             complement(33329..34618)
                     /locus_tag="PB779_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HDE0738666.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
BASE COUNT        10187 a         7172 c         6107 g        11235 t
ORIGIN      
        1 ttgtcttgaa ttgaatcaag acgccctaca catttggttt gtcttacttt gttcagtttt
       61 caaaggtcta cttcatcgag agtgtttccc gattcatttt tggctgccgt agcaactttt
      121 atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt ttcgatttcg
      181 tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat ttgtcaagaa
      241 cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt taacgactta
      301 gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc ataaaatgtt
      361 tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg tcaagctaaa
      421 atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat tgtttgcagc
      481 tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt gtactgcttc
      541 gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat cttctatagg
      601 cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac ctggagaaag
      661 gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct ttgattcagg
      721 tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat tgctattttt
      781 tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta catcaatcat
      841 attcagattt tctaccctga tattttcgat cactccccct ctttcttttg aagatttcat
      901 tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt cactaactcc
      961 agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac atctagcaac
     1021 ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc cagacttaat
     1081 agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat ttgttgaaga
     1141 atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta ctttttctac
     1201 taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct gaaaaatcaa
     1261 atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac gtttaatagc
     1321 ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc cgcttttttg
     1381 atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta ttccttttcc
     1441 ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc atttcatttc
     1501 tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc tccccttgag
     1561 gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg ctccgactaa
     1621 ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat cgattgcttt
     1681 ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca aagcattgat
     1741 aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt tttcaattct
     1801 tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa aatgattgcg
     1861 gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct ttcttgtact
     1921 aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag tgccagcata
     1981 aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga atttactcca
     2041 tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat cacgtcagta
     2101 atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat aaataaaaga
     2161 atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta catacatgaa
     2221 gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt cagctttgta
     2281 gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac agacattgct
     2341 tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc taaaatctga
     2401 ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt agctaacaaa
     2461 ccttttacca actgagaagc agatactttt tcgtttttga caactcttac tctttcagta
     2521 gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc gattgaaatc
     2581 caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt atacattaaa
     2641 atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct tcggaacgtg
     2701 gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc tccatacggg
     2761 atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat ataagcaatc
     2821 ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt cactaagcaa
     2881 aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt taactctgag
     2941 acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct cgaaatcaag
     3001 aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata aatcatcaag
     3061 aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat gtagcctatc
     3121 ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt aacagcattt
     3181 tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa ttataactct
     3241 ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt gacagataaa
     3301 aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt tacataacaa
     3361 tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc tcatttatta
     3421 aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa tcagcataac
     3481 ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca gtaaaccctc
     3541 ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca gttgatacgt
     3601 ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa gtcttctttt
     3661 ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat tctatcatac
     3721 gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa ttggattcat
     3781 ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat tcaaatgctg
     3841 tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt tcgaaggtag
     3901 attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt gtatcacacc
     3961 aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct ccttcaaatg
     4021 tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca atcattattt
     4081 cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac gtccaataca
     4141 cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt ctggtacaaa
     4201 gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt cctgtacatt
     4261 gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga tcaagctcgt
     4321 aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt cctgtaccgc
     4381 cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt gcctccgttt
     4441 tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc ttcttctctg
     4501 catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga cgataatccc
     4561 atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa gaaggatcaa
     4621 agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca gatgcagtga
     4681 tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct gtgtaaacaa
     4741 gataaaacaa tccatcagca taactgattt gtggcgccca tatacttcca tttgtaggat
     4801 ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag ttgactaaat
     4861 ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca ataatgtaat
     4921 accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa ataggatttt
     4981 tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga tataaactga
     5041 atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga gtgccaatca
     5101 acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat tttcctttag
     5161 cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca acggcaaaca
     5221 gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt gaatgatcta
     5281 cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt aaagtaactg
     5341 ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc aatagttccc
     5401 attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag gtcttttgat
     5461 cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat ttttcttgtc
     5521 atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg cttcaaataa
     5581 gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat caggttctgc
     5641 agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg tagatgctgc
     5701 tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat gaaaaacggc
     5761 atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt cataggtctg
     5821 acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat ctttttgcaa
     5881 atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac agttttttaa
     5941 agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt ctcctggacc
     6001 tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta agaaaaaagt
     6061 agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg caaaacgatt
     6121 accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc tgctttctat
     6181 atattcatca tatcttcctt cttttactat caagaccttt ggatggctat ccggcaggcc
     6241 tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat ctatagcatt
     6301 ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa ttgtttccaa
     6361 atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga agaaaagttt
     6421 tctggactac ccattgattg atactttttg tccagccctt ttctcagctt cagtacgcct
     6481 tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg cggagcgatt
     6541 ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata gtaataaaac
     6601 ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg tgccgctaga
     6661 tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa taagcctccc
     6721 atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt ctccaaataa
     6781 tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc tgttaataaa
     6841 aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc ccaagcatca
     6901 atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg agaagctaag
     6961 taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc gtgagaatgc
     7021 aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag ggctggtact
     7081 gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt ttgtttttct
     7141 cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa aaaatcattc
     7201 aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg attgatttga
     7261 ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg gtccctcgtg
     7321 attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat aaaatccttg
     7381 tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg catcttgggc
     7441 catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg ctaatccata
     7501 aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat ggatccttct
     7561 gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat acggttcttt
     7621 ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca cattatccat
     7681 gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc tagatttcaa
     7741 tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat tacgaatact
     7801 accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg tgcaatttgt
     7861 gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg ccttgattgc
     7921 aatacagtca tctcccacgt caatatggca attactaata cgcacatttt tgcatgattc
     7981 tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca agttatcaaa
     8041 cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga tcaatttaat
     8101 atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac gaggataagc
     8161 gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc catctaatgt
     8221 accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg aagcataaac
     8281 ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg gatcgtcaga
     8341 gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta aaaataaagc
     8401 tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac ttgctgcagc
     8461 atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc caaatgtcaa
     8521 aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa tgcaccaacg
     8581 cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga accatctcgc
     8641 tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag ccagccttct
     8701 tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac ttgtggaagc
     8761 cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta aacaaacata
     8821 ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt tacttgatac
     8881 catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt ttctagaatt
     8941 tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc tgctgcagcc
     9001 atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt ttttggatca
     9061 gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt ttttggatcg
     9121 aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc tttttcttca
     9181 ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc atccaaccaa
     9241 atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg tggatggttt
     9301 gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc tgtttctttg
     9361 tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc ttcaacgctg
     9421 tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt tatgaaatca
     9481 aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag tacgacgcca
     9541 tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg tgttctttcc
     9601 atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc tttaaaaatt
     9661 aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat attactgtgc
     9721 cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt gtgctttcca
     9781 gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt attgcaccgt
     9841 agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg gtgaatccaa
     9901 tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt gattagagaa
     9961 ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac gagagcttga
    10021 taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag aaccatcatc
    10081 attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca catcttcttc
    10141 taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt ttacttgaga
    10201 tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat gataaccgcc
    10261 gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt gaataccttg
    10321 acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag ttcttccttg
    10381 tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg ccaaatagcc
    10441 attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg tatcaaattc
    10501 tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa aataagaagt
    10561 gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa aaccaactgt
    10621 gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta cttcataaag
    10681 ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt ttcgaatgac
    10741 taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac cgtcgatact
    10801 cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt ttaaatattc
    10861 tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt ttttcaacat
    10921 cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag ttgttaatct
    10981 ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg ttttttcttc
    11041 gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat ttaaccaagt
    11101 gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc tgccgcatgc
    11161 ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg cttttttcat
    11221 aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt tctgtatatg
    11281 agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact gcggaaaaga
    11341 agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc atcagataaa
    11401 tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat ccgaataaaa
    11461 atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg attgggaaaa
    11521 tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc ctaagatacc
    11581 aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca tatatccagc
    11641 tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt ttcgtcaaag
    11701 gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca tacgatgcag
    11761 gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga aaattcaaat
    11821 aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac tgcagcatat
    11881 ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg gcaatcttat
    11941 tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt gctgtactga
    12001 aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa atttctgcaa
    12061 cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag tctaatgtct
    12121 gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc aatgtaacat
    12181 gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac aactgtgtat
    12241 cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct ttccagatca
    12301 cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg attttttcaa
    12361 atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa aatacataag
    12421 taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc gtttgaatcc
    12481 cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg attggcatcg
    12541 gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat aatgtaaaga
    12601 atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga cttcccatta
    12661 ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata ggaagatacc
    12721 taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat ttattcgttt
    12781 tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc gatagcgtca
    12841 gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt ttgtgaatgt
    12901 ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat catttttacc
    12961 gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat aaagtgtatt
    13021 ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga cacttagcat
    13081 aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata gaaacagaaa
    13141 catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc tataggagaa
    13201 agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat ctgtatcgtt
    13261 ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt cgcgaaaaag
    13321 tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct ttctacgccg
    13381 accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac gatcgtcagt
    13441 atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt tggtcgaggt
    13501 ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat tccaacgttc
    13561 ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct gcctgtggct
    13621 gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc ggatagtttg
    13681 gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa aattatgctg
    13741 ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac ttactggaac
    13801 acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat acagattctt
    13861 ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc cgttgatgtg
    13921 attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt gcctatgctg
    13981 attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg ttctgtcaaa
    14041 gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag cttcaagaaa
    14101 taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc ttatttttcg
    14161 aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt cagccttgag
    14221 cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa taagaagcga
    14281 ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat agcctgtctc
    14341 ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca gttctttttg
    14401 cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta ttctaacttc
    14461 ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa tatttttttc
    14521 gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa ttttgcggat
    14581 ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct ttcaaccatt
    14641 tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct cctgtttcct
    14701 ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg atcacatcta
    14761 aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc gacaaatttt
    14821 taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact aattgttcta
    14881 aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca taaatttgtt
    14941 tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga acgagttcat
    15001 tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt gcaaacaatg
    15061 catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga atggcttcaa
    15121 acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga gcagcaggaa
    15181 cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa tacagggctt
    15241 cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg ttactgatgc
    15301 ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt cggcaatact
    15361 ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata gtggcttgca
    15421 tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt tccgtgatca
    15481 tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct tctaacagat
    15541 cgatttgaac caaagctgta taatagcagt cattttgaga actataacca aattgctgca
    15601 accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt acaaatagcg
    15661 tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt tctcctatga
    15721 tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct tttgatttaa
    15781 gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa aataagtagg
    15841 aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg attctcagat
    15901 tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc caattattat
    15961 aatctgattt cagtactata tacgttttat ctttttctct tatcactttc agctgattgt
    16021 aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact gtctgagtag
    16081 taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt tcaccaacaa
    16141 cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt tctttttcaa
    16201 acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa aataaattat
    16261 ttttgttatt tatgtacttc tgttgatact tttcaacttc ctcttcggtc agttgactca
    16321 acgatccatt gattactccc catttaccag ccaaactgac taaatcataa ttattatcat
    16381 ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa gtggagtaat
    16441 ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa ccatacgtag
    16501 aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact tgcctgagca
    16561 aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc tggtaaatga
    16621 ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa aatattttat
    16681 aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa aggctttcat
    16741 ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc aagaatagca
    16801 taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat atcaaagatc
    16861 tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt gaaaaagtaa
    16921 ggaaaatgat ggaatggtaa cgatcaaaga tatcgctaaa gcagctggcg tttctcatac
    16981 gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa aacaaaaaat
    17041 acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag gtttagtgaa
    17101 tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa cttcatcaaa
    17161 tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt acagtttatc
    17221 tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct acgatggact
    17281 gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca aagaaaaaga
    17341 atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca acgtcactgc
    17401 cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg gacatacgaa
    17461 gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg aaaaaggggt
    17521 attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt taacaggaga
    17581 ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt ctgacctgcc
    17641 tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag ctgtacattt
    17701 agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt ctccagtcgt
    17761 ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa tgtgtcaaga
    17821 aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat ctaaaattga
    17881 gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta caagtaattt
    17941 tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa aaaactgaca
    18001 aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg tgaaggcaat
    18061 tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca attgtttaaa
    18121 ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat gaaccagcaa
    18181 gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt tgatacttcc
    18241 gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga tgcttatcta
    18301 tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga ggcaggaatc
    18361 caattcgtgg agactgataa tttaacagat actcccccac agagcttccc gggcaaactg
    18421 acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat cattccttgc
    18481 gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta cgcagaaaaa
    18541 tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt ctgttgtagt
    18601 ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt caatcaacgg
    18661 cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg ggtgatcgaa
    18721 gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa tgtcatcatc
    18781 acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg accgcataca
    18841 gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt aatgaaagat
    18901 cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc tatgctttct
    18961 ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt cttgaatcct
    19021 tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt cagcacccgt
    19081 ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc gttaatcact
    19141 gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc acatgatgat
    19201 gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc tattcctcga
    19261 ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa tgtgacagat
    19321 acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt attacaagaa
    19381 atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat taaatcgacg
    19441 agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga cgattgatca
    19501 gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat tgggtgattt
    19561 gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga cgacagacgt
    19621 aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg gtgaattgga
    19681 ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc gaacatttca
    19741 aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt tagtacctac
    19801 cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg aaaaacatcc
    19861 agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct gttcgcagct
    19921 tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc atcccaatgc
    19981 cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg aattcaaaaa
    20041 aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag atgtttacga
    20101 tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg aaaatgacca
    20161 gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg gttctgatgg
    20221 tctatcggga ataactgcta atcctttact tggtgcattt tctgactact tgattgctca
    20281 aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac aagtattgat
    20341 ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca atgacttcaa
    20401 acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg gtaataaagc
    20461 aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat caggaagctc
    20521 tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc ttagtttatt
    20581 gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg attgccagtt
    20641 ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa cggtcaaggt
    20701 atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta atgcaggcgt
    20761 cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa tcatcgctgt
    20821 agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg ccatttttaa
    20881 aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg aagatttatg
    20941 tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta ccattcctac
    21001 gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga aatttacgaa
    21061 aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta caaatggcgc
    21121 ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc tgattttgaa
    21181 aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct ttacagttgg
    21241 tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga agaaaatgca
    21301 gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg ccgtcgggaa
    21361 atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc agacgacttg
    21421 cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc ttcattccgt
    21481 ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac actactggaa
    21541 gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt agggcagcgg
    21601 atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga catcttacgc
    21661 tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg agctaacaaa
    21721 ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca tttgacccac
    21781 ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg taactgtaat
    21841 acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa tgatctttct
    21901 ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca gttgccaaag
    21961 acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt gatgggctgt
    22021 ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta caacgatact
    22081 cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt ggggaatttt
    22141 gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga atatttccgt
    22201 cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc tgaagatgaa
    22261 caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa ttactttggc
    22321 ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata gtgaaataac
    22381 ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc gtcttcttct
    22441 cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac atgcctacta
    22501 tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt cccgagacag
    22561 gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat aaccaagcaa
    22621 agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt ctagcttcac
    22681 agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag aaaatccaag
    22741 aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata ttttttgaat
    22801 gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga cgagattact
    22861 tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg atgcgtgcat
    22921 ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa gaattgttcc
    22981 agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct gatacttgta
    23041 aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc gctgataaag
    23101 ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct aattatttac
    23161 aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga tttagatgtt
    23221 cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca tatccaattt
    23281 gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact tgggagtgct
    23341 gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt aggatgctat
    23401 atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac tttcaaacag
    23461 caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac cggtagtgtc
    23521 tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc cagaaattct
    23581 atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt tgaagcaggg
    23641 atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga agtagcttca
    23701 ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa tcatgctgat
    23761 caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac agcgcttcat
    23821 ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg caagggctgt
    23881 ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat gtacgccact
    23941 cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca gtttatttac
    24001 caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc aaaaatatca
    24061 tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc gttttgccat
    24121 gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga tcgctattgc
    24181 caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca tttatttcaa
    24241 cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt ttcatgtaaa
    24301 ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc ttatcaagaa
    24361 aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa tccagtcaaa
    24421 gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg tcagcggatt
    24481 aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa gtcctgttgt
    24541 tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct ttttccgtaa
    24601 aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt ctgcaaaagt
    24661 gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa aacacgaaac
    24721 aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact tagatatcct
    24781 gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc tgatttgttt
    24841 gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg tcgtgatgta
    24901 tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc tgattcctac
    24961 gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg ctggcgatgt
    25021 agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc gttttgagga
    25081 tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt ctctagaggt
    25141 gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat ctacactcct
    25201 taacttattg attggattta tccagccgac ttcaggaaaa atttttctag atgatcagcc
    25261 tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc ctcaaaccac
    25321 tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa acgtatcaaa
    25381 agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg accagcttcc
    25441 tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg gccaaaagca
    25501 acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc tagatgaagc
    25561 aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga attacctgac
    25621 agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag aggcagataa
    25681 aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa aactgttagc
    25741 tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag ctatgacaag
    25801 acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact cctcggtcac
    25861 aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct tgtaactcag
    25921 agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag cctatcggca
    25981 ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc tctgttgttt
    26041 cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga tacggttcaa
    26101 gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga ttacttcttc
    26161 tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc tgaactcttg
    26221 tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt tgaacagttt
    26281 gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt tgaattctgg
    26341 taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg acatgttatg
    26401 ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt tttcaaaggg
    26461 gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt ccctgaacgc
    26521 cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca ccatattgat
    26581 tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt ccaacttgat
    26641 ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat cctgtttttg
    26701 aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca acatttccac
    26761 ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat gtcgaaatca
    26821 ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca tcgaaattag
    26881 tttctgtggt tcctgttttc cctgctatcg tataacctgc aggattcgca gcagccgctg
    26941 ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt tcctttgata
    27001 tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc gaatcaacga
    27061 ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca ctgtaagcac
    27121 ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag ccataatact
    27181 tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct ttttgtaaac
    27241 cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca gcttgataca
    27301 tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa ctttgcggtt
    27361 cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta tatacgctta
    27421 atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg aatcctctaa
    27481 agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc ggatctaaag
    27541 ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat aatgcactgt
    27601 tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta tagattttat
    27661 agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct tcatcgatca
    27721 ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat gtgtcattaa
    27781 gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg atttttccgt
    27841 tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt gggtgatcga
    27901 tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc tcagacagcg
    27961 taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca ccccataccc
    28021 cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg ctgtacttct
    28081 tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt tggtctaatg
    28141 tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc cctgatgttc
    28201 cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca aacccgtgat
    28261 gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag ggagaaatcg
    28321 cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct tcgtttttct
    28381 tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca tttgcttgtt
    28441 ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca atcagcaaaa
    28501 tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg aattgtccga
    28561 gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt tctaaaatgc
    28621 tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta ttttaccata
    28681 gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt acgttagtgc
    28741 aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat atgttttaaa
    28801 aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa tcacgatcac
    28861 tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg aatggttagt
    28921 tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca atcaacaacc
    28981 tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat tcgaagaaac
    29041 agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg ttttatatga
    29101 agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc caaatgaacc
    29161 gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta aacagcaacg
    29221 accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat ttgcaaaaaa
    29281 tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct atcggagata
    29341 tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata aaattggacg
    29401 agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga gcgccttgac
    29461 acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg ttttggaaac
    29521 cggacgtaca caccagatca gagttcattt agctcataag ggacatccga tcgttggaga
    29581 ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag aactgcacat
    29641 gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat tatgggaata
    29701 gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt ctttttgtgt
    29761 aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc gataatccca
    29821 ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt ttccatataa
    29881 ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc ctgattcatt
    29941 accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt gatcagtgct
    30001 tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag atcttgccct
    30061 ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa acaatcttta
    30121 tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca aatatgtccc
    30181 atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc tgcaccgatt
    30241 cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc ttgcttcaat
    30301 tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt gtagcgttcc
    30361 ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc caaaacgtat
    30421 ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat cccgattccc
    30481 ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc tggtgttgtg
    30541 gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca cacaaatttt
    30601 gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg attgtccgaa
    30661 tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca agcagattca
    30721 atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga ctagacatat
    30781 tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct gtaattgcaa
    30841 acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct tcatgatgtt
    30901 tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa gtagagaatt
    30961 tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct agacactgtg
    31021 cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga agtagcgtca
    31081 ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt ccgactgtta
    31141 caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga ttcgtggggt
    31201 tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata ctatctgctt
    31261 cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga tctttcatct
    31321 gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt gtcatgattg
    31381 tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa cgaaattcca
    31441 caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt tccatttcct
    31501 gtagaatact tatttttgct atttccggtg tatctactaa tacttttact tcagagtttt
    31561 ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata tactcatttc
    31621 ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg tttttgcgat
    31681 cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg ttttcgatga
    31741 ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc ccttctacaa
    31801 gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc actttgatca
    31861 ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca aattggacag
    31921 tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca tgatacttac
    31981 gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca gcgaatcttt
    32041 ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct gcagtattta
    32101 caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct gcggtcagct
    32161 gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca aaacgaggta
    32221 tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga ggatgatttt
    32281 gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca ctaacttcat
    32341 aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc ttggtattcc
    32401 attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag ccatccgttt
    32461 cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct ttttgaactg
    32521 cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac agttcatttg
    32581 cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca ccattcatca
    32641 tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc ttccaaaagg
    32701 caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa ttggcaaata
    32761 gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag tattgggaag
    32821 aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca ccacggccaa
    32881 acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc atatttccaa
    32941 atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt tcttccatgc
    33001 caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct tgcaagatat
    33061 aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc tgtctttttt
    33121 ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa tgaaaactgt
    33181 tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca atcagtcgca
    33241 tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga gaaatgatat
    33301 atactttctt tttcatttac gatacctcct acttttctac tctaatatca aagtaatcca
    33361 tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta taattttcag
    33421 gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt gctacaagta
    33481 aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc atagctaatg
    33541 caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt gcgtactttc
    33601 cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc agataatctt
    33661 cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc acattactgt
    33721 catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc gtttgccctt
    33781 tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc ttcaatttct
    33841 gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct tccacataac
    33901 ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg caagtatcat
    33961 cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca cctcgcccgt
    34021 cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa ggagagtgtt
    34081 catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca ataaaagatt
    34141 gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac tgtattgggt
    34201 agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt tttgtatgat
    34261 ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat ggatcgatat
    34321 tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat tcctcatctt
    34381 cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac cacatcgctg
    34441 gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact gttgtcaaca
    34501 gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata tccccacatt
    34561 tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta taagccacta
    34621 ataaaacctt ctttctattt gatatatctt taaagattat acttcataca gccaattatg
    34681 tctacgcttt caaaaaatat c
//
LOCUS       DAMEEU010000023        34126 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.024, whole genome shotgun sequence.
ACCESSION   DAMEEU010000023 DAMEEU010000000
VERSION     DAMEEU010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34126
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.024"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(29..1261)
                     /locus_tag="PB779_001130"
     CDS             complement(29..1261)
                     /locus_tag="PB779_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDE0738667.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1516..2085
                     /locus_tag="PB779_001131"
     CDS             1516..2085
                     /locus_tag="PB779_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0738668.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2263..2703)
                     /locus_tag="PB779_001132"
     CDS             complement(2263..2703)
                     /locus_tag="PB779_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDE0738669.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            2861..3625
                     /gene="map"
                     /locus_tag="PB779_001133"
     CDS             2861..3625
                     /gene="map"
                     /locus_tag="PB779_001133"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDE0738670.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3657..4580
                     /locus_tag="PB779_001134"
     CDS             3657..4580
                     /locus_tag="PB779_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDE0738671.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(4805..5044)
                     /locus_tag="PB779_001135"
     CDS             complement(4805..5044)
                     /locus_tag="PB779_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738672.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(5049..5468)
                     /locus_tag="PB779_001136"
     CDS             complement(5049..5468)
                     /locus_tag="PB779_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDE0738673.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            complement(5695..6933)
                     /locus_tag="PB779_001137"
     CDS             complement(5695..6933)
                     /locus_tag="PB779_001137"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0738674.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            complement(7040..7675)
                     /locus_tag="PB779_001138"
     CDS             complement(7040..7675)
                     /locus_tag="PB779_001138"
                     /inference="COORDINATES: protein motif:HMM:NF012655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0738675.1"
                     /translation="MARNKYPEETVKLILDVSTKMFCEKGYDNTSLQDIINETKLSKG
                     AIYHHFDSKEDILKAIFQRIGNENAVIFAKIRDNDSLNGLEKLREIFKTAVFNSNQSV
                     LLTVSPQLLNNPRFLAMQIEQMYEIVVPEFVEPVLEQGIKDKSLEIENSHEIAEVIMV
                     LSNVWLNPLVEMTDKEGMEKRCNTFNALLNGIGIDTLLDEETISAFIQFCK"
     gene            complement(8017..8652)
                     /locus_tag="PB779_001139"
     CDS             complement(8017..8652)
                     /locus_tag="PB779_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0738676.1"
                     /translation="MEGYAMKISHLGNNIQTIRKFRGMKQQELADKIGINMQSLSKIE
                     RGLNYPAYETLEKIMEVLDVTPNELLSGEWKYVNQSEKEVCQFLRAEERLNAELKHGH
                     YDNFFDSEEEWLEYELEKLREYITDYINGKSIEASDLYPIKEFIQHLKFQKLLDRYDD
                     LYSMDMFGESIEGHKYKTPYQVVKMINPNSKEDMELLREVLRNNNFDDEDE"
     gene            9164..10306
                     /locus_tag="PB779_001140"
     CDS             9164..10306
                     /locus_tag="PB779_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HDE0738677.1"
                     /translation="MNNLEFALEMKNKRLASGLSQGELASLTHVSRYSINRFENGKAN
                     ASKETQNIILRCLNYYICDKPFYLLVDYLSVRFPTTDALEVIRKVLGMKADYFIHYDY
                     GYYGYKEHYAYGEIKVMVSDDEHMGVFLELKGAGSRNMEYVLQAQNRDWYSFLNRCLD
                     CGGVIRRFDLAINDMCGLLDIPVLSEKYRNGGAECRCKNYENVQGGKLSGKNRNLAST
                     LYIGSKASTKYFCLYEKQKEQATKKKHTDIINRFEIRLRDKKAVQAVEELLLTYNPHG
                     LVFYLITDFVEFPDYPLWEIFISHDSLPFEMNPVPVNMERTLQWLERQVMPSIVMIEE
                     IDRLTGSNYMKMIDECTHLSEKQEMLVEQMCTDISDVIESEGVFYE"
     gene            10299..10505
                     /locus_tag="PB779_001141"
     CDS             10299..10505
                     /locus_tag="PB779_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDE0738678.1"
                     /translation="MSNTQDIPVWEKYTLTIEEASKYFRIGENKLRRLAEENKDAGWL
                     IMNGNRIQIKRRQFEKVIDKLDAI"
     gene            10584..11777
                     /locus_tag="PB779_001142"
     CDS             10584..11777
                     /locus_tag="PB779_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005336078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0738679.1"
                     /translation="MKEKRRDNKGRILHTGESQRTDGKYLYKYVDALGNTKYVYAWRL
                     TPTDPTPKGKREKPSLRELEQQIRRDIEDGIDSTGKKMTLCQLYAKQNAQRTNVKKST
                     QKQREQLMRLLKEDKLGARSIDTIKPSDAKEWALRMKDKGFSYNTINNHKRSLKASFY
                     IAIQDDYVRKNPFDFKLSEVIENDTKEKVALTEEQEQALLSFIKTDNVYHKHYDDVLI
                     LLKTGLRISELCGLTVADIDFKNEVVIIDHQLLKSKEQGYYIETPKTKSGIRQVPLSK
                     ETIQAFQRVINSRPKIKSIEVDGHSGFVFINPKGNPKVAIDYNALFIRMVKKYNKHHK
                     DNPLPHITPHTLRHTFCTRLASKNMNPKDLQYIMGHSNISITMNWYAHASIDTAKSEV
                     QRLIA"
     gene            11982..13121
                     /locus_tag="PB779_001143"
     CDS             11982..13121
                     /locus_tag="PB779_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HDE0738680.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            13114..13914
                     /locus_tag="PB779_001144"
     CDS             13114..13914
                     /locus_tag="PB779_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDE0738681.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            13914..14741
                     /locus_tag="PB779_001145"
     CDS             13914..14741
                     /locus_tag="PB779_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HDE0738682.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKQIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            14719..15453
                     /locus_tag="PB779_001146"
     CDS             14719..15453
                     /locus_tag="PB779_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDE0738683.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            15553..16419
                     /gene="rfbA"
                     /locus_tag="PB779_001147"
     CDS             15553..16419
                     /gene="rfbA"
                     /locus_tag="PB779_001147"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HDE0738684.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            16433..17005
                     /gene="rfbC"
                     /locus_tag="PB779_001148"
     CDS             16433..17005
                     /gene="rfbC"
                     /locus_tag="PB779_001148"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HDE0738685.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            17027..18055
                     /gene="rfbB"
                     /locus_tag="PB779_001149"
     CDS             17027..18055
                     /gene="rfbB"
                     /locus_tag="PB779_001149"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HDE0738686.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            18153..19004
                     /gene="rfbD"
                     /locus_tag="PB779_001150"
     CDS             18153..19004
                     /gene="rfbD"
                     /locus_tag="PB779_001150"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HDE0738687.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            19038..21071
                     /locus_tag="PB779_001151"
     CDS             19038..21071
                     /locus_tag="PB779_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738688.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            21115..22395
                     /locus_tag="PB779_001152"
     CDS             21115..22395
                     /locus_tag="PB779_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HDE0738689.1"
                     /translation="MEIIQAIVQKFVNKMSVGFLLLLLTLVFFVWTAGLGFPATLFIY
                     NNSSLLIAFSVAILLILNVYKAKGVDFLYLGVALALFIFFSYFRELRNESLFGDLLFP
                     LIILFCLVIKWIEWTKWDRGIYLIVFSVFLGITLYRVFTEIQVPEGQSIWAPGNSLSD
                     IWINTNIIGSSLMTLALLISGFASSFERWYVRIIGAVAVVAAFLGIWVCQSRGALVAL
                     IVFAILDLLPKSLMRVIRAPFIAYTVTILLALPISYLAAVSEKVNLFTGREDIWHKFY
                     QTLGEKSEQILLGMKTFIFQRGNQFLGNHNSYNSILNIYGLIGFGIAALLLILFIGRL
                     TLKADLSNGQMTFIWAFFAVMMQSFMEDTLTSYPWVPIIYILLAMAVHRYDEPEVAEE
                     FYVMEEAYDDMTYDDTSYEEQPDSAHSSRIQRYH"
     gene            22605..23411
                     /locus_tag="PB779_001153"
     CDS             22605..23411
                     /locus_tag="PB779_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738690.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            23423..24643
                     /locus_tag="PB779_001154"
     CDS             23423..24643
                     /locus_tag="PB779_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738691.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            24633..26219
                     /locus_tag="PB779_001155"
     CDS             24633..26219
                     /locus_tag="PB779_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDE0738692.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            26258..28396
                     /locus_tag="PB779_001156"
     CDS             26258..28396
                     /locus_tag="PB779_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDE0738693.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(28764..29747)
                     /locus_tag="PB779_001157"
     CDS             complement(28764..29747)
                     /locus_tag="PB779_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HDE0738694.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
     gene            30125..31516
                     /locus_tag="PB779_001158"
     CDS             30125..31516
                     /locus_tag="PB779_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDE0738695.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIEASGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            31532..32572
                     /locus_tag="PB779_001159"
     CDS             31532..32572
                     /locus_tag="PB779_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDE0738696.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            32591..33676
                     /locus_tag="PB779_001160"
     CDS             32591..33676
                     /locus_tag="PB779_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HDE0738697.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            33709..>34126
                     /locus_tag="PB779_001161"
     CDS             33709..>34126
                     /locus_tag="PB779_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDE0738698.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDV"
BASE COUNT        11073 a         5833 c         6719 g        10501 t
ORIGIN      
        1 tattttttgc atgtgtgcga aagtatactc aagcccaatc gccatttcgg aaaatcggta
       61 ctgtagagcc atcttcacgg attccgtcga tatccatctt gtcagatcct accatgaaat
      121 ctacgtgggt ttgacttcta ttcaatccag cttctgctaa ttcttcatcg gacatttctg
      181 taccgccttt cacactgaag gcataagcag aacctagtgc taagtgattc gatgcgtttt
      241 catcaaataa tgtattgaaa aagatgatgc cagattgaga aataggtgaa gggtcaggta
      301 caagtgcgac ttctcctaaa cgacgcgcac cttcatctgt atcaagcagt tttgctaaga
      361 catcttctcc ttgttcggca gaaaaatcaa caacttttcc atctttaaaa gtaaatttca
      421 tacccgagat gatggtgcca gcataactca gtggctttgt acttgaaatg taaccatcta
      481 ctcgatgact gtcaggtgct gtgaacactt cttccgtcgg catatttgcc atgaattttt
      541 ctccacgagc attatagctt ccagcgcctt cccaaagatg gtttttaggc aatccgataa
      601 tgatatctgt accgggagca gtatagtgaa gggcagaaaa ttgttctcga ttcaattctt
      661 ctgctttttt tgctaatttt tcatcatgct tcttccatgc taagacaggg tcttcttcat
      721 agacacgagt cgttttgaaa atctgatccc ataatgcctc aacttgtttt tcttctggca
      781 gttctgggaa gacttttgct gcccattgtt taccagccgc agccacgaca gtccaactga
      841 ctttatttgc ttgagttgcc ttgcgtaaat tcattagtgc tttgccattc gctgattgat
      901 aagacgctac tcgatggcta tctacaccag caaatgcatc gggatcggca gaaacaacgc
      961 tgatcctgct tgctcctttt tcaagccatt catccgcttg atcgatttta gattgtggta
     1021 cattctcaat acgatccgtt gcagcatgta aaagaaattc tctttggatc tggtcgtcag
     1081 tccattgaac gataacctca gcggctccta gtttataagc ttcttgtgtg atcaatcgag
     1141 caaggggtgc ctgttccacg ctgatctgta aaacaactgt gtgtcctttt tctgtggcta
     1201 cgccagtttc tgcaattaag cgtgcatatt tttttagaag ttcattaaaa tcagataaca
     1261 taataaaaat tcctcctcac cattttttct ggtaactatt agcatgatac catttaatta
     1321 tgattcaaac aatgaggctt taaataaaaa aaggaggtta tttttttaag gttaagtttc
     1381 atgatatatg ttactacttg ctatttcagc ttgtgaagaa aatcaaaaac taattttgca
     1441 tatcaaaaaa aacatgttac aatgaaatta atcaatggtg gaagcgttat aaaaaaatta
     1501 aggagattaa aaaatatggc aagaaaaaag acgattacta gagaacagat tttggcagct
     1561 gcttatgaag tagctgccac cgatggattt acacgattta ctgcgagaaa catcgcgaac
     1621 aaaatgaatt gttccacgca accgatttat cttgagttta aaaatatgga tgacttgaga
     1681 caagctcttt ttgagcagat ctatgatcat ttacaatatg aagtgttcac tgttgagcat
     1741 acagggaata cgattatcga tcttgctttt aattatatcc attttgcaag aagagagaag
     1801 aagttgtatc gttcactgta cttagaagaa tatggtggag gaaaagagat gcagaatttc
     1861 tcttatactt actttgtgaa tacagtgaaa cgcgatccag cttatgtgaa tctttcagaa
     1921 gagcagatcg aatctttgta taatgggaca tggatcatag ctactgggat cgcagctttg
     1981 atgtcttcaa gcatcatcca tccaactgat gaacagattg aaaagatgat ccaagacagt
     2041 atagatgcta tcttgaaatt caaagaacca atcgaaatcg attgaatata ctcaaaagtt
     2101 ccacaaatca gtaggtaaca agagatgtgt caaaataagg aaaagttcgt ttttcttaca
     2161 gcgtatgcat ttttaactcc cgaagaactc ttccatgaat gcaatgaata aaagagccat
     2221 acagattgaa taaatctgga tggctctttt attgcaagta tattaaattt ttgcgactag
     2281 ttctttagcg aaagcttcta aattttcgat atcttcttct tcagcattca gatccacttt
     2341 aacattttcg gctccttttg atgcgcctgt ttttgcaaaa gcagcatcga aatcatccac
     2401 cgatttgcag aattcatcgt aaaaagtatc accagatccg cagacaccgt aaatttttcc
     2461 caatagatcc aattcttgca agtcttcata aaagtctacg atctcatcag gcagatcgcc
     2521 atcatcgtat gtataagtag ctactacgca aatatctgcc tcctcgaatt catctgcatc
     2581 tacttgggta cattcgttga tttcgacttc gatatccaga ttttcaaatg cttctgcaac
     2641 aatatcggcg atttcttcag tgtttcctgt catgctagca tatacgattt ttgctaaagc
     2701 catgatgtgc ctcctcgttt ataattattt aacaattatg aattatacca aaacatcatt
     2761 gaaaagaaaa taaaacctag agacacctgg ggaatgtcat ttggctaaat gtatgccgct
     2821 atgttaaaat gagagggatt tgtaaaaagg agacgaaaat atgattactt taaaatcagc
     2881 acgtgaaatt gaaatgatgg cagaatctgg agctttatta gcagatgtac ataaaaatct
     2941 gcgtgatttt ataaaaccag gaatcacaag ttgggatatt gaggtatttg tcagaaacta
     3001 tatcgagagt catggcggaa ttgctgcgca aattggcttt gaagggtatg aatatgcgac
     3061 ttgtatcagt ataaatgatg aaatttgtca tggattccct cgtaaaaagc ctttgaaaaa
     3121 cggtgatttg gtaaaagtcg atatgtgtat cgatttgaaa ggcggcattt ctgattcttg
     3181 ttgggcctat gtagttggag aatctacacc tgagatcgac cgattgatgg aagtaacgaa
     3241 gaaagctttg tacatcggta ttgagcaagc acaagtaggg aatcggattg gtgacatcgg
     3301 tcatgctatc caaacttatg tagaaggcga aaatctagcg atcgttcgtg attttattgg
     3361 tcatggcgtt ggtcctacga ttcatgaaga accagcagtt cctcattacg gagaagctgg
     3421 aaaagggttg cggttgaaag aaggcatggt tatcacgatc gaacctatgg ttaataccgg
     3481 aacttggaaa atgaaaatgg atcctaacgg ctggactgcg tatacaagag acggcggact
     3541 ttcttgccaa tatgaacata cattggctat tactaaagat ggtccaagaa ttttgacatc
     3601 acaaggagaa gaaggcactt attgatctat ccagtcaata ggtacgggag aggtacatga
     3661 aagtttggaa caaaataaaa caaaatgaaa atctgatgcg ctttattgag acgactcaaa
     3721 agcgcatcac tgattcagaa atgagtacga cctctgtcgt cgttgcttat tatttactct
     3781 tgtctttatt tccattgatt attgcttttg gtaatatttt accgtttctc cacatcgatc
     3841 aagagactgt actgacctat ttacgagaag tgattcctga gaccgtttac cagtttatcg
     3901 gtcctgcaat caaagacctt ttgacacaaa gttcaggagg cttgttatcc gtttctgcat
     3961 tagcggcttt atggtctgca agtcaaagta tcaatgcttt gcaaattgcg atgaataaag
     4021 cgtatggcgt agaaaataga aaaaattttt tgatcgtccg tttcttctca ctaattgtca
     4081 ttgtcttgtt catgattgct attagtgggg taactatcgt tcttgggttg ggacagctga
     4141 ttttggatgc tattcagcca atcgtacaaa tacccgtgaa ctttatcgat cagttccaaa
     4201 ctttgaagtg gccaatcaca ttggtagctt tatttgtcat catgttcttg atttatttaa
     4261 ttgtccctaa tgctcagttg aagttgaaga cgatcattcc gggcacgatc ttcgctactg
     4321 tcggctggat gctgttatca caagtgttta gtatctatgc taggtatttt gcaacgagga
     4381 tcagcggtta tcagatcata ggaagtttta ttgtactcat gctttggctt aattttgctg
     4441 ctacgatcat cattttgggc ggaatcatca atgcagttgt tcaagaatac gtgacgggtc
     4501 atcaaatcaa aaaacgtcga gatccaagcc gaaaatggtt caataaattg aaaactaaat
     4561 tttctcataa aaaaaagtag aaacaagagt tcttattgta aatttatatc agtaatttat
     4621 ttgaaatttt atatctaatt ttcaattatc cgcataaaca ctatacattc aagcattttg
     4681 aagtatagaa aaacactcat cttaccacga atttaccacg attgaatgag ccttgatatg
     4741 accgtaaaac tactaaggga gatagcacga aactgtgtat ctcccgattt ttttatacag
     4801 ttgattactt cactccgatt tcaaatttca atattgcttt catcatgtct gtatgaattt
     4861 ctccttttag ttcttcatca acctgcataa tgattttacc actttcagag tggtaaaaag
     4921 gacgcaagca taatttagaa atataaccgt cataaaactt caaaatctct ttaactgcca
     4981 tttcatctcc gcttgacgct ttgcaaatca attcaaaaga gggatagcca taatctttac
     5041 tcatttcttt acttcctttc gctcaaaagc atttttaact tccttagtcc tctagttctt
     5101 ctactgcaaa tagcagaacg tgatacatgg tacagttctg aaatttctct gtcgttcatt
     5161 ccttgaaaat aacgtaataa aatcgcacta cgctgttttt ctgacagtct atgtaaaact
     5221 gtaccaagtg tttcatcaga tacataaatt gtaaagtgca agactttaaa tgatacacaa
     5281 tcataaaaac aggtatcaat cgttccacgt tcaacttgtt tcgtttcggc tatttcacaa
     5341 aacaatactt cacgtttaga atgtcttgca agctgtctgt ttcgactttt cactttgttc
     5401 ttaatgacaa tcagcattaa agaattgaac tgtaatctga cgatatgctc gaaagaagat
     5461 gtcctcataa tctcaccccc tttctgctaa tgctgaaata tataaacgga ataccgttta
     5521 taccctttag aaatacagaa aaatggtaag aaaaaagccc acacaaaaca tatatttgtg
     5581 cgagccttaa atactgcaat attactcttt cttttataac actatccttt tagcagattt
     5641 caaattttct tttatatatt gtttttagcc taacatacta tttaacccct tgtattatat
     5701 ctctaacttt tgaaaaattc tttttgaata tattgaaatc atgattgaag caatagaagc
     5761 tacaaacata acaacccatg tttcttgtat aaatacatcg aataaaatac cgtaaaccat
     5821 ttgtccaata ggttgaccgc acatagcaac tgctaccagc gtagccatta tctttcctac
     5881 taattgcggt ggtgtttgtg tctgaacaag agtgtaaatt tgaacaacaa acatagtaga
     5941 tacacccata gccacaaagc acatcactgt aactacccag taggaaacta ttgcaggcaa
     6001 ttctaaaaat agcgaaattc ccataagtaa aacagaaaca gaacaaataa gtaacaaggt
     6061 ataaaggttt tttagtttta actttgaagc aacaagagct gttaaaatac caccacataa
     6121 accacctaat gataatgctg attgtgaaaa accatatagt gtatctggca tttttaaaac
     6181 ttcagaaatt aagataggca gaccaacaat taaaacagca cttaaaacca aattgaaaat
     6241 gcaaaccaaa aagattacgg atataaaaat gggtttctcc tttttcaaaa aggtataact
     6301 atcttttaaa tcgtttttag caactgcaat tacacctact tcacgaggtc ttttttggtg
     6361 tggaatatgg ataaaaattt ccataatggc tgaaaaagta aaacatataa tactaacaat
     6421 taaaatggga ttgataccat aaaattgaaa aactactccg cttatagctg gtccgataaa
     6481 gtttgctaaa gtatttactt gatttattat agcattaccg acggtaagtt tatctgatga
     6541 taccaataga ggaatacttg cttgtaccgc tggttgatat gcaccagaaa taccataaag
     6601 taacatcaaa gcaacaataa acaaaggtat gataggaatt tttcccaatg acaaataaaa
     6661 tactaaaatt atgattgctg ttacaaaatc tagtatgacc ataatgtttc ttttatttgt
     6721 cctgtcagca ataataccac ctaccagcga caaaataacc ataggtaaaa aagagcaggc
     6781 tgtagcaata ccaaacaaag ctgatgaacc agtttctttt aacaaatagt acggtaatgc
     6841 aaatcgtagg atagcgtttc caaataaaga aattatctgt cctataacaa caagtataaa
     6901 atcacgatta aaaagttttt tttctgcttg cataaaatct ctccttttta tttaatcaaa
     6961 cagaccgtcg gtttatataa tggtttaaat aaactgctct tttatagagc agtctatcgt
     7021 atagggataa caaatacagt tatttacaaa actgtataaa tgcagaaatt gtttcttcgt
     7081 ctaataatgt gtctatgcct attccattta aaagggcatt gaatgtattg caacgttttt
     7141 ccataccctc tttatccgtc atttcaacta atgggttgag ccatacatta cttaatacca
     7201 tgataacttc tgcaatttca tgtgaatttt caatctccaa agacttatcc ttgatacctt
     7261 gttctaaaac gggttcaaca aattcaggta ctacaatttc atacatttgt tctatttgca
     7321 tagcaagaaa acgaggattg tttaatagtt gaggagaaac tgtcaataaa acgctttggt
     7381 tagaattgaa taccgctgtc ttaaatattt ctcttaactt ttctaaaccg tttaaactat
     7441 cgttatctct aattttagca aatattactg cattttcatt tccaattctt tgaaaaattg
     7501 cttttaaaat atcttccttt gaatcgaaat gatgataaat agcaccttta gaaagttttg
     7561 tttcattgat aatatcttgc aatgatgtgt tatcatatcc tttttcacaa aacatttttg
     7621 tagaaacatc taaaatgagt tttactgttt cttctggata tttatttcgt gccataactt
     7681 acctccaata caaaccgttg gtctgattaa agtatatctt agtattttat gcttgtcaat
     7741 ataaagactt gcaattttat aaaaatgcag aatgcaagcc tttttcattt attctacaat
     7801 cttccagttg ctttccttat gcggtgtcaa ttcatactgt gatacctgcg ttgcctttgc
     7861 ctgatttacc acaaatcaga ttttatccct ttcttcctct tgattgccca caacagaaaa
     7921 gaaaaagccc tgtcaagagc tttgccacca ttggtggtgc tttgcactct tgatcgggct
     7981 ttttgtttgc tgtatcttct cgcaagagga aaaaagttac tcgtcctcat catcaaaatt
     8041 gttattcctt aatacttctc gtaacagttc catatcttct tttgagttcg ggtttatcat
     8101 tttcacgact tgataaggtg tcttatactt atgtccctct atgctttccc caaacatatc
     8161 catactgtat aaatcatcat agcggtctaa taatttttga aacttcaaat gctggataaa
     8221 ttctttgatt gggtaaaggt cggacgcttc aatgcttttc ccgttgatat agtctgtaat
     8281 atattcccgt aacttttcta actcatattc cagccattct tcctcgctgt caaagaagtt
     8341 atcatagtgt ccatgtttca gttctgcatt tagacgttct tcggctctta aaaactgaca
     8401 gacttccttt tcagattgat tgacatactt ccattctccc gacaacaatt cattgggcgt
     8461 aacgtccagc acttccatta tcttttccag cgtttcatag gcaggatagt tcaaccctct
     8521 ttcaatcttg gaaaggctct gcatattgat accgattttg tccgcaagtt cctgttgttt
     8581 cattccccta aattttctta tggtctgtat attatttcct aaatggctta ttttcattgc
     8641 ataaccctcc atatctcgtt atatcttcgc tattataagt ctatcatgct taatatgatt
     8701 tgtaaaggca aaaaaagata ttgacaaata agcatataag aattactatg ttcttgtaat
     8761 cgaataagca caatagaatg aaatataaaa acattcaaaa agaaatacct atctgattaa
     8821 atccgtagat atgaatatcg gttgaaatgg aacttgttag aaaaggcaaa acagaacttg
     8881 ctgacaaagt atttctgaca cggtggcgga agcctctcag gcttaccgcc atgacacctt
     8941 gtgtcaaggg gaagaaatgc tttgtcggct ggcgagcctg cgagccttgt ctgtgccccc
     9001 gttatctaac aggggggcac tatttcacaa aagacaagtc aaaaaccata cacccccaaa
     9061 cctgtgagta gtaatgagag gttttaagaa gatagtacat atcacacttt ttgaaaggtg
     9121 gtttacaggt atttcaaggc tattgtggga ttggaggaat acaatgaaca atttagaatt
     9181 tgcacttgaa atgaagaaca aacgtcttgc cagcggtctt tcacaaggag aacttgcaag
     9241 tcttacccat gtatcaagat atagtatcaa ccgctttgag aacggaaaag ctaacgccag
     9301 caaggaaaca cagaacatta tcctgcgttg tctgaattac tatatctgcg ataagccttt
     9361 ttatctgctc gttgattatc tgtctgtccg ttttccaacg actgacgcat tggaagttat
     9421 ccgaaaggtg cttggcatga aagcagatta ttttatccat tatgactatg ggtattatgg
     9481 ctataaggag cattatgctt acggggaaat caaggtcatg gtttctgatg atgaacacat
     9541 gggcgtattt ttagaattaa aaggggcagg ctcacgcaac atggaatatg tcttacaggc
     9601 acagaacagg gactggtatt cattcttaaa ccgctgtctt gactgtggcg gtgttatccg
     9661 acgttttgac ttggcaatca atgatatgtg cggtctgctg gatattcctg tgctatctga
     9721 aaaatacaga aatggtggtg cggaatgtcg ctgtaaaaac tatgaaaatg tacaaggtgg
     9781 aaaattaagc ggaaaaaacc gtaatttagc aagtaccctt tatatcggct caaaggcaag
     9841 cacaaaatat ttctgcctgt atgaaaaaca aaaggaacag gcaacgaaaa agaaacatac
     9901 cgatattatc aaccgttttg aaattcgtct gcgtgacaaa aaggcggtac aggcagttga
     9961 agaactgtta ttgacgtata accctcatgg gctggtgttt tatctcatta ccgattttgt
    10021 ggaatttcct gactatccat tgtgggagat attcatttcc catgacagtt taccttttga
    10081 aatgaaccct gtacctgtca atatggaacg cactctgcaa tggctggaaa gacaggtcat
    10141 gccgtcaatc gtgatgatag aggaaatcga caggctgaca ggttcaaact acatgaaaat
    10201 gattgatgaa tgtacccacc tttctgaaaa acaggaaatg cttgtggaac agatgtgtac
    10261 ggacatatca gacgtaatcg aaagtgaggg ggtgttttat gagtaataca caggatattc
    10321 ccgtatggga aaaatacacc cttaccattg aagaagcgtc aaagtatttc cgcattggag
    10381 aaaacaagtt aagacgattg gcagaggaaa acaaggacgc tggctggctc attatgaatg
    10441 gcaaccgcat acagattaaa cgccgacagt ttgaaaaggt tattgataaa ttggacgcaa
    10501 tctaatgcaa atgagccttg tatgtgttat gatgaacaca agtcatatca aggctctttc
    10561 caacaaggaa aggagcagac accatgaaag aaaaaagacg ggataacaaa ggtcgtatcc
    10621 tgcatactgg agagagccaa cgaacagacg gaaaatactt atataaatat gtagacgcat
    10681 tgggaaacac aaaatatgtg tatgcttgga gattgacacc cacagacccg acaccaaagg
    10741 gaaaacggga aaaaccctca cttcgagaac tggaacagca gataagacgg gatattgagg
    10801 acggtatcga cagcacaggc aagaaaatga cgctttgcca actctatgcc aaacagaacg
    10861 cacagaggac aaatgtgaag aaaagcacac agaaacaacg ggaacaactc atgcggttat
    10921 taaaagagga caagttaggt gctaggagca ttgatacgat aaaaccctct gacgctaaag
    10981 aatgggcgtt acgcatgaaa gacaaaggct tttcctacaa taccattaac aaccataaac
    11041 gctcgttaaa agcgtcattc tacatagcca tacaagatga ttatgtgagg aaaaaccctt
    11101 ttgatttcaa gctaagtgaa gtcatagaaa atgataccaa agagaaagtc gcattgacag
    11161 aggaacagga gcaagcctta ttgtcattta ttaagacgga caacgtgtat cacaagcatt
    11221 atgatgatgt gctgatactg ttaaagacag gacttcgtat ctcggaactg tgcggactga
    11281 cagtagccga cattgatttc aagaatgaag ttgtgattat cgaccaccag ttactaaaga
    11341 gtaaggaaca gggctattat attgaaacgc ctaagacgaa aagcgggata aggcaagtgc
    11401 cattaagcaa agaaacgata caggcatttc aacgggttat caacagccga ccaaagataa
    11461 agtcgataga ggtagacgga cacagcggtt ttgtgtttat caatccgaaa ggtaatccaa
    11521 aagttgccat tgattataac gccttattta tccgtatggt aaagaaatac aacaagcacc
    11581 acaaggacaa tcccttgcca catattacac cgcatacgct acgccataca ttctgcacaa
    11641 ggctggcaag caagaacatg aacccgaaag atttacagta tatcatgggg cattcaaaca
    11701 tcagtatcac aatgaactgg tacgctcatg cgtccataga taccgcaaaa tcagaggttc
    11761 agcgtctaat cgcatagaag tatttaccac gattttaacc acgattgaca gggaaaatat
    11821 aagaagatag acctagatat gcgaggttta ccacaaaagc aaaatgcccg tagagccgat
    11881 aaaataaggc tttgcggaca tttgagaaga tataaaaaga tagtcaaaaa gacatatata
    11941 atttataata attatgactc ttaattaaag taggtgccca tatgcttgtt tcttttagta
    12001 tggttataag attttttctg acaattttat tatcactgat attaacacct gtattcaaaa
    12061 tcatttcagt acaaacaggt atggtcgaca aaccaaatga aagaagaata aataaagttc
    12121 caatgccttc agcgggcgga ctgcctatct ttatttcatt tgttatatcg actttattct
    12181 tattccgtaa aattatccct caatcgtata ttgtaccgat cttgattgct tctttagtaa
    12241 tcatagtcac aggagtgctc gatgataaat atgagctgac acctaaacaa aaaagtatag
    12301 ggatcttgat tgcttctctt attatttatt ttgtagcaga tatacgtatt gattccttca
    12361 cgcttccttt tattggatat atccaactag gctggcttag ttttcccgta acgatttttt
    12421 ggatcttcgg tatcacgaat gcggtcaatc tgattgacgg tttggatggg ctggcggcag
    12481 ggatttcatt gatcggttta attacgatag gaatcattgg atattttttc ctccatgctt
    12541 ctacagtgta tattccagtt gttattttct gtcttgtagc aagtattatc ggtttttttc
    12601 cttacaattt ttatccggca aagatttatt taggcgatac aggagctcta ttcctagggt
    12661 ttatgatggc cgtcctttca ctacaagggc tgaagaacgt gacttttgtt tcatcgattt
    12721 ctttgctgat cgtcatggga gtgccggtaa cagacacgtt ttttgctatc attaggagaa
    12781 aagcaaaccg tgtttctttt tctacagcag ataaaaaaca tcttcatcac cgactaatca
    12841 gtttaggctt tactcataaa ggtgctgtcc tgacgattta tgcgatggct ttgatgtttt
    12901 ctttcacagc tatggtcatg aattatactg gaagaatcgg aacgatcata ttgattattg
    12961 ccatgttgtt tgctgcaatt ttattatttg aattgattgg tctgatcaat gagaaacatc
    13021 agtttatttt aaaaacattg cgatttttag ggaataaaga gtaccgtacg caagtaaaac
    13081 agaaatattt gaagaaatgg aaccgtcata tagatgaata acaaattaaa ccagccgatc
    13141 cttattagta ttgtgacggc aaacagtgat aaaatttttc ggacactaga taattttatt
    13201 tcaactgtaa aagatgaaac agcagtaaaa atccgaattt ttgacaacaa ttcacttccc
    13261 gagtacaaaa aaagactaac agagtatagg aaatatccct acatcgatat ctattttcat
    13321 gatgaaaatt ccggatttgg ttatggacat aatcacaatc tgatagctag cgattctcgc
    13381 tatggcatta tttgtaaccc agatatttta gtggatgaag agacagttac agcattggtc
    13441 ttgttattga aagaacatcc ggaatgtgcg atgttagcac ctaagattct taatgaagat
    13501 ggaacaactc agcacctcat ccgtgagcag ctggctgttt ttgattacgt tttgcgcttt
    13561 gtgcctttca aatgggtcaa aaaaaagttt gacaaacgac tggctgtgtt tgaatgccga
    13621 ggattgccta ctgatgctaa tagttatgta cggatgatct caggtagttt tatggtagct
    13681 gatattgata aatttaaaga gataaagggg tttgatgagc gtttcttcat gtactttgaa
    13741 gacaacgact tgtgtttgag ttttgaaaaa gcaggttaca agttattgta cacacccttt
    13801 tatgcagtta tccattttta cgggaagggt gcgcatcgaa atgcaaaact gtttcgcgtg
    13861 tttttgactt ctatgatgaa atttttcaat aagtgggggt ggcgtttttt ctgatgaaac
    13921 cagaaatatt agtagtcgtt gtgctttatc agcaactatt cagtcaatct ccagcttatg
    13981 gaccattaag caaagcactt agcgaaaagc aaattcagct tattatttac gataatagtc
    14041 ctcaaaggca gcaaaatgag ctgtttgaaa aagaaaatat cgtttatcat catgatccgc
    14101 aaaatcctgg tttagcggtg gcttataatt ttgcgttgtc tcaagcagat gaaggaacac
    14161 gttgtctcgt cactctggat caggatacga ggctagtcga cgattatttt gaactattgc
    14221 gtaaagtaac ctttacagat gaatgtgttg ctgcagttcc gatgattttt tctgggagcc
    14281 gacaagtttc tcccctatat tcagatcgtt atatcaatcg tacagctcaa gcagtagaag
    14341 ttgaaggccc aacagctgaa cgaatcatgg caatcaattc aggtgttgcc tggtctgtca
    14401 aatttctaaa aaagattggc gggtttaatc ctgctttttc tttagatttt ttggatcatt
    14461 ggctgttttg gaaagtggat cagttggaaa aaactgtgga gatccttcct gtacgaatgg
    14521 aacatgatct ttcggtttta gactatgaaa aagtttcaag taatcgatac cgttctattt
    14581 tacaagcaga aaatcgattt tatcatgaat atgatcaaag gcatttatcc agtcaccgac
    14641 gacaattatt gttaagaaca gctaaacagt tcttgaccgt caaaaaccgg catatctggc
    14701 ggatgacttt gcgctcatat gttaagaatt ggaaggtgtg aattcgtgcg ttcggtttgt
    14761 atagctacct ttaatggagg cagatattta agagagcagt tagatagtat tttatctcag
    14821 ctttcagcag aagatgaagt agtcatttct gatgatgggt cagtagatga tacatgggat
    14881 atattaactg aatacgcaga aaaagataag cgaatccagc ttttttcggg gcctcgtcaa
    14941 ggattgatcg ctaattttgg ttatgcgatc cagcagacga aaggagatct aatctttttg
    15001 gcagaccaag atgatgtttg gttggagaca aaagtgaaaa agatcactga ctattttgag
    15061 cagaatccgg atcagctagt agtagtttct gatttaatca ttgtggacag cgagctgcaa
    15121 gagatccatg attcgtattt ttcgtttcga aattccaaag aaggatggct taataatgtg
    15181 ataagaagtc actatattgg tgctggtatg gctttccggt cttctttaaa acccgatatt
    15241 ttgccgatcc cgtcagaagt gccgatgcat gatatgtgga ttggtttgct gggaggaaag
    15301 aagactgggt tcctaagaga accgttaact ctgtaccgaa gacatgattt aaacgcgagt
    15361 gagattgaaa cacattctaa attacggcaa aaaatttctt ggcgtgttca tctgattacg
    15421 gcgttgatca aacgaaaatg gtttaaacgt tgataaaaga tgtttaaatc cttaatattt
    15481 ccatgacaaa tataacaatt gatgagataa taacaaagtg aaatttgaaa tcaaaaagga
    15541 gagcagatat ccatgaaggg aatcattctt gctgggggca gcggaacacg tctgtaccct
    15601 ttaacaaagg caacatcgaa acaattgatg ccgatttatg acaaaccaat gatttattat
    15661 ccaatgtcta ctctgatgtt ggcgggaatc aaagaaattc tgattatttc aacgccacaa
    15721 gatacaccac gtttcaagga attatttgga aacggaaatg atttaggact gcagatcgaa
    15781 tatgcagtac aagaaagtcc agatggattg gcacaagcgt ttatcattgg agaagaattt
    15841 attggagatg atagtgtctg cttggtatta ggggacaata tttactatgg tggcggtctg
    15901 tctaaaatgt tgcaacgagc agcttcaaaa gatacaggcg cgacagtatt tggctatcat
    15961 gtcaatgatc cagaacgctt tggtgtagta gaatttgatg agaatatgca agctttgtcg
    16021 attgaagaaa agcctgctca gccaaaatca aattacgctg taactggcct ttatttttat
    16081 gacaatgagg taatttctat cgctaaaggt atcaaacctt cagaacgtgg agaactagag
    16141 attacggatg tcaataaagc atatttggat aaaggaaaac tatccgtaga acttatggga
    16201 cgcggatttg cttggcttga tacaggaaca catgaatcat tgcttgaagc atctaccttt
    16261 atcgaaacaa ttgaaaaacg tcagaactta aaagtggctt gtttggaaga aattgcttac
    16321 cgtatgggct acatcgataa ggaacaattg ctggcccttg cacagccatt gaaaaaaaat
    16381 caatacggtc aatatttatt gaatttggcc gctgaataag gagtccttac agatgaaagt
    16441 aacagataca aaattaacag atgtcaaaat cgtagaaatg gacgtctttg gcgatcatcg
    16501 cggtttcttc acagaaagtt attcaaaagc aaaatttgca gaacatggat tgaaatatga
    16561 ctttgttcaa gacaaccatt cactatcagc tgaagctggt gtccttcggg ggcttcattt
    16621 ccaaaaagga gaagctgcac agacaaaatt gattcgggta gtcactggag cagttttaga
    16681 tgtagtagtg gatatccgca aaggtagccc gacttatggt caatgggacg gatttatctt
    16741 atctgaacat aatcatcgac agttgcttgt acctaaagga tatgcccatg gattcgttac
    16801 tttgacacca aatgtgaact tcctttataa gtgtgataat tactataatg cagaagcaga
    16861 tgggggcatc gcatttgatg atccagattt agcgattgat tggccaattg atccatcaag
    16921 agcgattatg tcggaaaaag atcaccgtca tccgacatta aaagaatttg aagcagaaaa
    16981 tccatttgtt tacggagaaa tctaagaatt aaggagaaat tttcttatga aaaacatcat
    17041 tgttaccgga ggtgccggat tcatcggctc taatttcgtt cattacgtgg taaacaatca
    17101 tccagaagtg catgtcactg ttttggataa actgacttat gcaggaaaca aagagaactt
    17161 ggctggactt cctagcgatc gcgtagaatt ggtcgtagga gatgttgcag atgcagaatt
    17221 agtggaccgt ctagtaaaag aagcggacgc agttgttcat tacgcggcag aatcccataa
    17281 cgataattca ttaaaagatc ctttcccatt tgtacaaacg aatatcattg gtacgtatac
    17341 acttttagaa gcttgccgca agtatgatgt acgctatcat cacgtatcta ctgacgaggt
    17401 ttacggcgat cttccattac gtgaagacct gccaggacat ggggaaggcg aaggagaaaa
    17461 attcactgcg gaaacaccat ataatccttc aagtccatat tcttctacaa aagctggttc
    17521 agatctgtta gtaaaagcat gggtgcgttc ttttggctta cgtgcaacca tttcaaactg
    17581 ttcaaacaac tatggtcctt atcagcatat tgaaaaattt attcctcgcc aagtaacgaa
    17641 tatcttaagc ggtattcgtc caaaattata tggcgaagga aagaatgttc gtgactggat
    17701 ccatacgaat gatcattctt cagcagtgtg gctgattttg acgaaaggca gaattggcga
    17761 aacctatctg atcggtgcag acggtgaaga agataataag accgtgatgg aattgatctt
    17821 agaaatgatg ggtcaaccaa aagatgcgta cgaccatgta aacgaccgtg caggacacga
    17881 cttgcgttat gcaatcgatt cgacaaaatt acgggaagag ttaggatgga agcctgagtt
    17941 tacgaacttc cgtgatgggt tggctgacac gatcaaatgg tacgaagaac atgaagactg
    18001 gtggaaaaaa gaaaaagagg ccgttgaagc agcatatgcc aaaaatggac aataatacag
    18061 agaaaatgtc actgtattaa tggaaaaaca catgtgaggc aggcgctcgc ctgtctcttt
    18121 tttaaaataa aaatcaagga gcggataatc atatgttttt attaactgga ggaaatgggc
    18181 aactaggtac agaattgcgc catttattag atgaaaaaaa tctgcaatat gtttcaacag
    18241 atgcaaaaga cttggatatc acagatgccg agaaaacaat ggcttacatc acagaattaa
    18301 aacctgatgt tattttccat tgtgcagctt acacagcagt agataaagca gaagaagaag
    18361 caaaagaatt agatgagaag atcaatgttg atggtacaag aaatgtagca cttgcagcaa
    18421 aagctgtgaa tgctcaattc gtctatatca gtacagacta tgttttcgat ggaaaaaaca
    18481 aaaatgtaga atacgaagta gacgaccaaa cgaatccact aaatgaatat ggtcgtacga
    18541 aattattagg cgaaaaagca gtagaagaga ttttagaaga ctattatatc atacgaactt
    18601 cttgggtttt cgggatctat ggacacaatt tcgtcttcac gatgcaacgc ctagcggaaa
    18661 cccgcgacaa actgactgta gtaaatgacc agtttgggcg accaacttgg acacgtactt
    18721 tggcagaatt tatggtatat gtcatcgaag aaaaagcacc atttggtatt tatcatttgt
    18781 cgaacgaaaa tagctgttct tggtatgaat tcgcaaaaga aatattgaaa gatacagatg
    18841 tagaagttgc acctgttacg tcagaagaat ttccgcaaaa agcaacacgt ccgcagtatt
    18901 cagtcatgag cctgaaaaag acagaagagt taggatttgt cataccaact tggcaagaag
    18961 cacttgcgca aatgctggaa gctgccaaaa aaatgaataa gtaatttcct tttatcaaat
    19021 agaatttgga gcatgatatg gaaaaacaaa caagaagtgc acgacgaaaa gaaaagccaa
    19081 aagcgaacca ggcagattcg aatttggtgc ttgacctgtt tctaaaactc cgctatctta
    19141 ttggcgtttt agtcatcgtg gtcatcgtta cttttaattt aaacggaagt tcacttggtg
    19201 tttgggataa atatgtgtcg caaagagacg atgggaaaaa aactgatgtg atttttggac
    19261 agaatcggga agtgcggtca gacgaatggc tggtgcagac acctttttac ctctcacaag
    19321 ctgaagagga ctttccgttg gtgaacgagg attattcatt aaacggacaa aacatgatca
    19381 ttgcgtataa ttctcctgta aaggatatta cggttatcgg aaaaccattc aactggggat
    19441 tctttttcct cggaagagat cgaggacttt ccttttattg ggcgatgaaa ttagtcgtca
    19501 tggtcttgct tggattcgaa gtactgatga tattaacgaa gagaaaaaaa gctctatcgc
    19561 taatcggtgc atttgcgctg acattttctc cagcagtcca gtggtggttc atgcaacatg
    19621 tgggcgattt gattttcttt actttgggac tgatgactgc tttttatcat tatttctaca
    19681 atcatgataa aaaatggcta cgaacgttga tgatgctttt ggtggttatt ttcggtattg
    19741 ggtttatttt agtgatttac ccagcccatc aagtgatgct ggcgtacttg ctgatttttt
    19801 attttgttgg cctgcttatt tactatagca agaaagtttc atgggatctg ttggatgtag
    19861 tgttgattgg aggggcagtt ttatttattg gcggagtcat ggttcatttc tggctaacgt
    19921 caaaagacgc attgttagct tctttgaata ccttatatcc aggaaaacgg gtaagtactg
    19981 gaggaaagtg gacgattggc gaattttttt ctttccttac aaattggaaa attccttttg
    20041 aagatatcaa ctattcgaat aactctgaag tggccctgtt ctatcacttt tttccaactg
    20101 tattcctagc aagtccattt gtgttatttg gcaaaaaaga tagcgaacaa aagttactgg
    20161 gacgtatttt gatgattttt tgtctgtttt ctatcttttg gattaccgtt gggttgccaa
    20221 aatggctagc agaaatcact ctgctgtctt atgttcctcc attaagagcc atccttactt
    20281 ttagttttgc ggcttgttta ttatcgatct ggtttatcgc ttatatttgg agagaagatg
    20341 ttattcctat ttggtataaa ttcattttgt tggcagtaaa tgcatggtct tatttctatg
    20401 cgattacgca ttcgaaaatg gataattatt tttcggattt tgaaaccatc gcagttgctg
    20461 tgttgggaac agtgatttta gcttttgcat tatttggctg gagacgcttg ttttacctcg
    20521 cttttgccgc cttagttatc gtatctggct ttttcgtcaa tccagtcgta gaaggtacag
    20581 gagcgatttt tgaaaaaaca ctggcaaaag aaatccaaaa aatcgatcaa caagatcctg
    20641 gtaaagtttg gttgtctgaa gatgaattat ataacttcac cccaacattg ggagtgaaat
    20701 ccttcaatac agtacgcttt tatccagata tagctgcatg gaagaaaatc gatccgaaag
    20761 aagaatacga gaagtattat aatcggtatg ctcatacaag agcttttatc gctaaggaag
    20821 atacaaagtt cattttagat cgtccagata tgttttcggt cacgttgaat tttgaagacg
    20881 cagaaaaatt agggatcgac tatgtgatca gtaaacgacc attaactgat tacaaccaat
    20941 tatatgaagc gcagttcacg cagctatatg gaccggataa agacggttat atgattttta
    21001 aagtagaata tccggattat ccagatgtac cacaaacaca aactcaggaa aatcagctag
    21061 tcgtacagta ataggctagc tgagaataat cctgaaatgt tagtagaaag gagagtggag
    21121 ataattcaag caatcgtaca aaaatttgtc aacaaaatga gtgtcggttt cttgcttttg
    21181 ttactgacgc tagtcttttt tgtttggaca gcagggttag gttttccagc aactttgttt
    21241 atatataaca atagttcatt acttatcgct tttagtgtgg ctattttgct cattttaaat
    21301 gtttataaag caaaaggcgt cgattttctt tatctaggtg ttgcgcttgc ccttttcatt
    21361 ttcttttctt actttcggga attaagaaat gagtctttat ttggagactt actgtttcct
    21421 ttgattattt tattttgttt agtaattaaa tggatcgagt ggacaaaatg ggatcgcggt
    21481 atttatctga ttgtcttttc ggtcttcctc ggaatcacgt tatatcgtgt atttacagag
    21541 atccaagtac cagaaggaca aagcatctgg gctccaggca attcgctttc tgatatttgg
    21601 atcaatacga atataatcgg aagttctttg atgactcttg ctttattgat cagtggattt
    21661 gccagttctt ttgaacgatg gtatgtacga atcatcggtg cagtagcagt tgttgcagct
    21721 tttctcggga tttgggtctg ccaatctaga ggtgcattag tcgcgttgat tgtttttgcg
    21781 atattggatc ttttacctaa atcgttgatg cgtgtcattc gtgcgccatt tattgcttac
    21841 acggttacga ttcttttagc tttgccgatt tcttatctgg cggctgtctc tgaaaaagtc
    21901 aatttgttta ccggtcgaga agatatttgg cataaattct atcagacgct aggagaaaaa
    21961 tctgaacaaa ttttactagg aatgaaaaca tttatcttcc aacgaggaaa ccaattttta
    22021 ggaaaccaca atagttataa ttctattttg aatatctatg gattgatagg atttgggatt
    22081 gctgctttgc tgcttatcct ttttattggt cgcttaacgt tgaaagcaga tttatccaac
    22141 gggcagatga cttttatctg ggcctttttt gcggtgatga tgcagtcatt tatggaggat
    22201 acattgactt catacccatg ggttccgatt atttatatcc tgttggctat ggccgttcat
    22261 cgatatgatg aaccagaagt tgcggaggaa ttctatgtta tggaagaggc atatgacgat
    22321 atgacttatg atgatacatc ttatgaggaa caaccagata gcgctcattc ttccaggatc
    22381 caacgctatc attgataggc acaaaatacg agagaggctg tgacaaccgt cgcagccttt
    22441 tttggtttat tgcaattgtc tagcatcttc tgtaaaatag aaacgttaga gaaaatcttg
    22501 tatcatagaa aattaagaaa gaaataagaa cgcagctcgg taccaaaaat atggtaaaat
    22561 ggcacttgac tgtaattcac tgaaaatcgc ttggaggaac acaaatgttt aaagatttgt
    22621 atttatttat gaaggacatt tatcagaaca gaaaattatt gctacagttt tcgatcaatg
    22681 acttcaaatc aagatatgca ggatcgtttt taggaatctt atgggcgttt atcaatccgc
    22741 tatttactgt attgatttat tggctggtat ttggtgttgg actgaaagca caaatgatcg
    22801 atgcaaaata cccatttatc gtatatttag ttaccgggat gattccctgg ttcttcttct
    22861 cagatgcatt tgcatcaact acggttgttt ttcgggaata tacttattta gtaaagaaag
    22921 tcgtattcaa tattcgtatc ttgcccacga cgaaaatcct atccaatctg tacacccact
    22981 tattcttcat tctgattggc atagctgtcg cgcttataaa tggtatatat ccttcagcaa
    23041 tgtctttaca gctgatttat tatttatttt gcatgtgtgc tttcttgaca ggattgactt
    23101 ggctgacggc atcgatccaa ccatttttac ctgatatcat gcaattaatt acgatcgtgc
    23161 tgcagttgat catgtggaca ttaccgatat tatggagccc taatcagttt gattcaggtc
    23221 ttgtaagcat attgaaatta aatccgctgt actatgttgt tcaaggttat cgtgagtcat
    23281 ttttaagtga agcttggttc tgggagcatg gaacatatac tttgtatttc tgggttttca
    23341 cgttagtaat gttcgtaatc ggctctgcag tgttccgtag attgaaacca catttttcag
    23401 atgtgctgta aggagaatag ctatgacaga atatgcaatt agactaaaag atatcacaaa
    23461 atcttataat atgtacgcaa aaccttcgga tcgatttcgt gaagccctca atccttttaa
    23521 gaaatcctat catgatgtat tttatgcgtt gaaaaacgtg aatgtagaaa taaaaaaagg
    23581 tgagatgatc ggtttcgtgg gagaaaacgg atcgggaaaa tctacaatgt tgaaaatcat
    23641 tacgggagta ctgacaccaa catccggcac gatggaaatc gaaggaaaaa tctcagcttt
    23701 gctagaacta ggatcaggat tcaatcctga gtattctggc tatgaaaata tctatttaaa
    23761 tggaatggtt ctaggatttt caagagaaga agtcgatgaa atggtcgatg atatcattga
    23821 atttgctgac atcggagacc atatttatca acctgtaaaa acttattcaa gcgggatgtt
    23881 cgttcgtcta gcttttgctg tagcaatcaa tgtgaatccc gatattttga ttgtggatga
    23941 agcattggca gtaggcgatc ttgaatttca actaaaatgt atggaaaaat ttacagaaat
    24001 caagaactcg ggaaagacga ttttattcgt ttctcatgat atcagttcga ttcgtcgttt
    24061 ttgtgatcgt tcctattggt tgaaaaacgg agaagtcgtc gaatatggcg atacgatgga
    24121 agtaacgacg aattatgaaa actttttaaa gaaaaaatca gttaaaacag tggatcggaa
    24181 taaaaaccaa gtagaacggt tcgccgctcc agatatcgtc gacgtgacga aagcggaatt
    24241 gttggataaa gacaaaaatc cggtggatat gctggaacaa ggagaaaaac tatacgttaa
    24301 agtaacttat gaagtaaaag atgatacaat caaaaatccg gttttaggaa ttgcgctacg
    24361 aacagtcgac aatttttatg tatgcggact taatactcta ctagatggta tcaagattcc
    24421 ttggaaaaaa ggagagaata tcttttatct ggagtatgaa aagttaggtt tgttagctgg
    24481 tgaatattat tttgacgttg cggtctttga agaaaatgca acggttcctt tggtatataa
    24541 gacaaagtac atgaacttgt ttgtcagcgg ttcttatatc ggagaaggca tcgtggtctt
    24601 agaccataaa tgggaagaag ggactcatag caatgaaata tgattttgaa atggacctag
    24661 atgaacaaag cagtgtggga aaaattgccg cacagatcaa accaggaagt aaagttttag
    24721 agtttggtcc cggaaacggc cgattaacga aacatttaat cggagcaaaa caatgtgaag
    24781 tgagcattgt tgagttagat aaggaattgt tcgattttgt cagcgaattt gctcaagatg
    24841 gattttatgg tgatatcgaa agttttgagt gggcaaacta ttatgctgga cagacatttg
    24901 attacgtctt gtttgcggat gttttagaac atttggtaga tcctggaaaa acattgaaga
    24961 aagtcagaga atttttgaat gaagaaggag agatcctgat tacattccct aacttggcgc
    25021 ataattctgt catgatcgat ttgttcaata accaattgcc gtgggcttct tatggtctcc
    25081 tagatgaaac ccataattct ttttatactc atgatggctt ccaaaaagtt tttgaaaaag
    25141 cgggattatt cattaatatt gaagattatt tgtacttagc tgtaggtgat acagaattaa
    25201 aatcaactta tgaagaattg ccggaagctg tacgctatga tttcaaaatg cgaccatttg
    25261 gtgaagtcta ccaatacttt ttctcattga tgaaacatcc agtagcacaa agttccattg
    25321 cagagccaca aaattctaat tatgtaaaag tgttagaagt aacccagcaa acgaaacaag
    25381 atgaaacaat ccaacaaata ccattcaata atttcacagg ggaaaatgag acactaagtt
    25441 tccccgtatc agaaacaaca gaaagaatgg tgtttcgctt cgcgcaacaa cctagcttta
    25501 tcgaattcag cgcagaagct gccggagaaa aactaacatt tatcgattcg aatgctgtag
    25561 tcaaaacagt aaatgattgt tatttgtttg atgggaaaga attaccagag ttcgttctaa
    25621 cggatatttc tgggaaagaa gtgactatcc attgtcacta tcgctttatc ggggaattga
    25681 caccaacaat gaaagaattg ttggaaacga ttcgtcccat ggctgaagtc acaaagcagc
    25741 tttctgagaa aaatgacgaa ttagaaagag aaaatcatca tcttcttgag gaaaatacaa
    25801 gactagacca tacgttaaaa acaaccacaa atcgctattg cacattgttg gaaagtgatg
    25861 aatggacaat aaaacataga ctaggacgac gtaagaaaga aacttcgaaa aaaatccaag
    25921 aaaaagaact ttctatatgt attgacgaga aaatctggga tgcagaaaca aaaatattaa
    25981 aaatcatcgg atggggaatc gctaattcgg atcgccagcc cttgtcctat aagttatcag
    26041 ctgaccaatc gccatttttc gaagcaattc ctgtttcacg agaagaagtc aatcaagcag
    26101 aacagctcgc aaaaggaaca gaagcgggat ttgagttacg aatcctttgc gagcaagaac
    26161 gttcattctt agtggaagca gtagctcaaa atggccaatc atggatcatt gaaatgtaaa
    26221 taatgattaa cttataaaga taaggagtaa acgaatcgtg caaaaaaaag aaattgccgt
    26281 atttatcgat caaatcactc gtgaacgggc cactggcgat ttgcttattg tgggctgggc
    26341 aattgatgaa gtgaccaaag aaatccctac gataaaggta gaaaaagaaa atgtgattgc
    26401 tgaagcaaca catgtcgtaa gattggatat caatcattta tataatcttg atgttaagac
    26461 ccaaagcggt tttaaggtac gtttatcagg gaaaatgaga ggaaaagcca tcttagactt
    26521 ccaaacagcg agacatcaaa atggcatagc tgtgaaatta aacggtaaat acccttatga
    26581 tgacggcatt gaatcttcat gggaaagaaa aaaaagatta ctgaaaaaag ggataaatta
    26641 tgcaaggact catggcgtaa aaaaagcgat ccgtcgggtc aaattggaat tgaagccagg
    26701 atcgatcgac tatgcagagt ggatcagtcg tcatgagaaa ccagatttga aagagcaaag
    26761 gaaagaagca caaggatttg cgtaccgtcc attgatttcc atacttatgc ctgtctataa
    26821 cgttgaaatc aaatggctcg aaaaatgcat tgattcggta ctggatcaaa cgtatgatca
    26881 ttgggaacta tgtatcagtg atgatgcttc tactgatcca gctatccgaa agtgtctgga
    26941 atcctatcaa gcaaaagatg atagaatcaa agtcgttttc cgaaaagaaa atggacacat
    27001 cagtctggca actaattctg cattggaaat agcagaagga gaatttatag cactcttaga
    27061 taatgatgat gaattaccgc catttgcatt atatgaagtg gcaaaagtgc taaacgtaca
    27121 tccagaactg gatgtgatct acagtgacga agataaaatc gatgcagatg gcaatcgctt
    27181 tgatccgcat ttcaaagcag actggtcgcc tgatacattg atgggaaata attatatctc
    27241 tcacttaggc gtatatcgaa caagcattgt taaagaactt ggcggtttcc gtaaaggcta
    27301 tgaaggttct caagattatg atttggtcct tcgtgtgaca gaacaaatcc ctgcagatca
    27361 tatttaccac attgaccgag tcttgtatca ttggcggacg atcccaggat caactgcaag
    27421 taatggcgaa gccaaaagtt atatctatga ttccggagtg aaagcattga cagatgccct
    27481 gtctagaaga aacatcaaag gaagcgtacg tcctggcaga atttctggat tttatgagat
    27541 tgcttatgac gtcttgcaag aggatttggt cagtgtgatc attccaacga agaatggcta
    27601 tgaagatcta aaaacttgtg tggattcgat catcgaaaaa acgtcttatt caaattatga
    27661 aatcattatt gcggataacg gaagtacaga tccaaaaatg caagaattat ttgcagaata
    27721 caagcatcag ctgaaagacc gctttatcgt agaattgatt gacattccat tcaattattc
    27781 tcgaattaac aatttagcag cagaaaaagc aaacggcaaa tactttttat tcttgaataa
    27841 cgatacagaa gtgattgagc cagattggat gacggtgatg gtttcttatg cacagtttga
    27901 tcgaatcggc tgtgtaggag caaaactgtt ttatccagat gatacaacgc agcatgcagg
    27961 agtattatta ggaatcggtg gtgttgcagg gcatgcattg aataactatg atcgaacaca
    28021 ttgtggttat ttcggccgat tggtcattga cgtcaattac ttagcagtca ctgcagcttg
    28081 tatgatggtc aaggcagctg acttcaatgc tgttaacggg tttgatgaaa cattagaagt
    28141 agcattcaac gatgttgact tgtgcttgaa agtttatgaa ctgggtcgtt acaatgtcta
    28201 tgcacatcaa gcagaattgt accatttcga atctaaatca agaggttatg aagatactcc
    28261 agaaaaacaa agacgttttg ctggtgaaat caaaaaaatg caagataaat ggccagcata
    28321 tattgcgcat gatccatttt acaatgataa tttaacaaaa gaaggaatcg gcgacttttc
    28381 gttgagacca gattaaacta taataaaaag ctgttatgtt gtgattcgct cgcacataac
    28441 ggctttttat agttttttgt caaaaaaagg cagaaggtgc cgactcaaaa aaataagtcg
    28501 aggttgggac agaagtgttt aactccgaga aataagaaga aattcacgaa aattgctttt
    28561 caaatttttg tgaatttcgg cttatttaag aagaagttgc ttctgctccc accgtttatt
    28621 cgtttttaaa gaatgagaca aaagtgtttc ttacttttgt cccacgctct tattcatgct
    28681 cagagcgcca atagatacaa aatcatagcc aaagtttcac gaaccctagc tgtcaaagaa
    28741 tcgatatttt attttaatat aggctatttt aaaataaatg gtttaaggta ttcctctaca
    28801 aaagccactc tatcaattat catgggttta aaataagaag tgatggagat aaccagattg
    28861 ttcttagcgt caatataaag aacatttcca ctattaccaa ttgctgaata tatttcgttc
    28921 tcagaatcta atacccacca taaatagcca tatctcatat tttgtaagtc ttctaaagca
    28981 ctggttctag gtttgaacat ctcgtttatc cacatgggtg gtacgatttg ttttccttta
    29041 tacatccctt tatttaggca taatacacca atttttgcca gatcacttgc cgataaacac
    29101 aaaccatatc ctgccgtccc gatatttagt ggatcacaaa accagacatt ggttttagga
    29161 gacttatcca ttgtaaactg cttatgttct tcagctgttt cagcataata attgacatgg
    29221 tttggtatcc ctataggatc aaatagatac ttattggcaa aatcaacagt tgttagctta
    29281 cttgtctgat acaacaagcc agttaatatg tgtaaacaga cagtttgata gttgaattcg
    29341 ccggttatac cttttcttcc tcccaataaa tctagtgatg tttttgtcca atcttcactt
    29401 gaacagactt ttgtccatgg atcgccttta catttgtagg gtgctttcat tgttagcaag
    29461 tgcttgattg taatagcgta aatagttttc tccccgcgtt tcactttata ctctggaaaa
    29521 taatctaata ctttatcatc gatacttttg attaatcctt gctctaaagc aatgccaatc
    29581 agcaaagata caatactttt cgttgctgac atgatatgac aagtatcgtc ttttttataa
    29641 ccattccatt catctgtata aacttctacc ccatccttat atgcgacaat ttgacatata
    29701 tttggttgtc gaaaaccaat aaaatcatgc aactcttgtt tattcataag atattacctc
    29761 actttcttct ataagcataa tgtcattaaa aatcgatttc aattttttcg attcttcacg
    29821 taatacaggt attcttatgg actagacagc gctttgggaa gatggattct ctgaaaaata
    29881 taaaggttca ctttatgagt ggataaaaaa agcagcaaat acttcgactt ctttaattta
    29941 ccaacattag tgaaaatcga ttcatctgga gatttgtaat ttagagtcct tgtcttgatt
    30001 agaggtgtat aaagcttttt attagacatt tttaaattcc attacaattt gcttataaac
    30061 taggttttta aaggtgacta tggtaagata atagagatat tattttgtga ttaggagtgt
    30121 atatatgaat aaaaatggag aatggagtgc tgcacgacgg atattcatta tattaatgga
    30181 tgttattgta tacaatgcag caatatatag tagtttctta ctgaagtttc gtggagagat
    30241 cccattacga aatttagaaa ctttccaaca ctcagcaatt attatttcag tgatttttat
    30301 tgcgttgaac attttgttgg gtgcatatgt tttttataat cgaatgatca gtgacatcgt
    30361 gtttgtcaca gtcatcggtc aggtattgat gacactaggg atcatggtag tgacttttgc
    30421 gggccgctgg tttgcttttc cacgtcttgt tatcttactt tcatttgttc tcggtacgct
    30481 tttcttaagt atctatcgta ttctcgtata taaactttat ttacgcgtaa gtcgagataa
    30541 aaaggtcgtc attattgggt tagaaaagga tgtcgcacca gcaatccaaa attttggttc
    30601 aaagaaaaac aacaaacata aagtcgaagc agtcattctt gataactatt atgcaaacat
    30661 caaaaatatg attaaagaca tcgatattgt ctatcttgct tctcatatcg aagaaactga
    30721 aaaaatcaaa atctatcaat tagttactaa aaatgaaaaa aaattgtttt tgaatacaac
    30781 atttgaaaac ttgacattga tcaatccaaa tattatgaat ttcgaagatg aaagtattat
    30841 tgaagcatct ggatttagaa tccaacctga atatgaacta ttcaaacgtt tgtttgatat
    30901 catcgtttca cttgttttat tagttattgc ttcaccattt atgttattca cagcaatttt
    30961 agtcaaagtg acatcaccgg gaccaatcat ctataaacaa gtgcggatca caaaaaatca
    31021 aaaggaattt tcaatctata aattccgctc gatgaccgcc acagccgaag caaaatctgg
    31081 accagtttta gctaagagca atgatgcacg agtaacgcct gtaggtaaat ttattcgagc
    31141 tgtccgcttt gatgaattac cacaaatctt caatgtgctg aaaggcgata tgtcgatcgt
    31201 aggaccacgt cctgaacgtc ctttcttcgt cgatcagttc aatgcagaaa acccttatta
    31261 ctacttacgg cataatgttc gtgctggtat cactgggtat gcacaagtct atggaaaata
    31321 tgtctctgat tacaacagta aattacgttt tgatttactt tatatcaaaa aatattcatt
    31381 gatgcttgat ttaaagatct tgctgcaaac catcaagatc ctatttgata aaatgtcctc
    31441 tcaaggactt gaagaagacg aaaatgtgat ctcattggca gaaattgctt ttccgaatga
    31501 aaaaatcttt cgctagttgg gaggcgtaaa aatgaacaat ccgaaattca gcataatcgt
    31561 accagtatac aatgcagaag caactattgg tcgaacgatt gatattctaa aagaattgga
    31621 ttatgaagag tacgaagtcg ttttagtaaa tgatggatca acagatcaaa cacaggaaat
    31681 cattcaagaa ctgattgaaa atgatgaacg ttttgaattg attactacga ccaatcaagg
    31741 gcccggatta gcaagaaacg aaggaataag acagtcaaaa ggagaatatc tcttattctt
    31801 cgatgcagat gacacgccag taaaaacgat cttgtcagat tatgatcatt tgctagaaaa
    31861 gagtccaaaa gcggatcttg ttgttagttc gtttgttttt cgtacaatgg acgagggaag
    31921 aatcgtttcc gaaaaagaaa acttagttac agaatgtcac tatctaactc acgaagagtt
    31981 tataaaagac atgtatcagt taatgaatga acagttgatg tatgttgtat ggaacaaatg
    32041 ctatcgtagc gatattctga aaaataacca aattctattt aaaacttata atagttgtga
    32101 ggatcgaata tttaacttac attattatga atactgtcat caagtgatca tgaacccaaa
    32161 agtagaatat atttatgaat ttgaaggtgg gaaggggatc actaatcaat accgacctaa
    32221 caagttcgaa acatttaaag aattctattc attagcaaat actgtaacag acgatattaa
    32281 taaagacggt atggcggcgc ttcttttaaa agggacaact tcagttattt tttctattta
    32341 tagtacctct gcaagaactt caaaagagaa gaaagacgaa gcaaagcaga tattgagtga
    32401 tccagtgatc cgagaagcca agcaaattgc taagacggat tcttcagcaa aaaaaataac
    32461 aaagttgctt tacaatatgc cagctccact atttttatct gctgtaaaag ttggaagctt
    32521 cgttgaagtg aaaatgccag ggttaatggc tgctttgaag cgagtatatt agttaatgga
    32581 ggaaaatata atgaaaagaa ttttgcattt tcagggacga atgggtttag gtggagcaga
    32641 gtctttcatg atgaatttat atcgtaaaat tgatcgtaca aactatcaat ttgatttttt
    32701 gatttatgaa gattatgcag atgttcaaga ctatcattca gagattgaaa gattaggagg
    32761 ccgtattttt gttgtaccta atcctaagaa aaatattttt aaatatttaa tagaagtgaa
    32821 taagttacta aaaaaagaat ctttttctat agttcacaat caggtttatt ttggcggggg
    32881 aattaattta tggttagcca aaaagaatgg aatcagacag agaattgctc atagccatgc
    32941 aactgaagat ggaaaatctc aaaatattgt aatgaatgta ttgcgtaaat ttttaaccaa
    33001 attgttgtta caaaatgcaa cagactacct tgccgttagt caagaagctg gtgaaagtct
    33061 gtttcaaaac cacccctttg agatagttca taatggtatt gatttagagc tttatagtaa
    33121 aaattcagaa gctaaggtta ataagagaaa agaattggat atctcaatga gtacttttgt
    33181 tgtgggaaac attggacgat tagagaaaca aaaaaatcaa tcttatttgt tagagatttt
    33241 tttagaaata ctaaaaatga attctgattc ttacttgatt ttagtaggtg aagggtcact
    33301 tagaaataaa ctgaaagcca aagcagtaga attggatata gagaaaagag taaaattttt
    33361 aggagaaaga aacgatattc ccgagttatt atctgtgatg gatgtttttg taatgccttc
    33421 tctttatgaa ggtctgccaa tggttggatt agaagcacaa gcagcaaaat taaaattagt
    33481 cttagcagat actatttcca aagatacaaa gttaacaaat aatgtggatt ttgtatcatt
    33541 agatgaaaca ccacaagaat gggcaaaaaa agtaataaaa gagccgtatg ctaataaaat
    33601 aacacaagaa ctaaagagtt atgatgtttc gtacactact gaacaaatgg agagtatata
    33661 tagtagagat cattaaaaat gttcaagata ttttaggagt gattattttt gaaaatatgt
    33721 tatttgatat tggcatacaa tgatattggc aacttaaaga gattggtcaa tcgattgaac
    33781 gaaaatgcag tttttattat tcatatagat aaaaaaactg atatagaacc atttattgaa
    33841 gcatttaaat catatgataa tgttgaattt ttatgtaata aaaaccgtgt taaaatttat
    33901 tggggtggtt tttccattgt acaagcagaa atcaatttag taaagagagc attacaaaat
    33961 gagaaatatt taaaatatgt attattatct ggtgctgatt atccaatcaa agataatgag
    34021 tatatttata attattttaa aaagaatagt tcagtggagt ttattcgtgg aatagatcta
    34081 gatcaaatta aacataaaga attttattat aaacatatag atgtat
//
LOCUS       DAMEEU010000024        34118 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.025, whole genome shotgun sequence.
ACCESSION   DAMEEU010000024 DAMEEU010000000
VERSION     DAMEEU010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 34118)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34118)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34118
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.025"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(99..1229)
                     /locus_tag="PB779_001162"
     CDS             complement(99..1229)
                     /locus_tag="PB779_001162"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HDE0738699.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="PB779_001163"
     CDS             complement(1878..3080)
                     /locus_tag="PB779_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0738700.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="PB779_001164"
     CDS             complement(3140..3343)
                     /locus_tag="PB779_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HDE0738701.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEHLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="PB779_001165"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="PB779_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="PB779_001166"
     CDS             4880..5692
                     /locus_tag="PB779_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738702.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6913)
                     /locus_tag="PB779_001167"
     CDS             complement(6716..6913)
                     /locus_tag="PB779_001167"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HDE0738703.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="PB779_001168"
     CDS             complement(7059..7937)
                     /locus_tag="PB779_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDE0738704.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="PB779_001169"
     CDS             complement(7976..9094)
                     /locus_tag="PB779_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HDE0738705.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="PB779_001170"
     CDS             complement(9091..11190)
                     /locus_tag="PB779_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HDE0738706.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="PB779_001171"
     CDS             complement(11241..12062)
                     /locus_tag="PB779_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDE0738707.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="PB779_001172"
     CDS             complement(12059..12868)
                     /locus_tag="PB779_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0738708.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="PB779_001173"
     CDS             complement(12889..13383)
                     /locus_tag="PB779_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0738709.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="PB779_001174"
     CDS             complement(13395..13883)
                     /locus_tag="PB779_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0738710.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="PB779_001175"
     CDS             complement(13960..16656)
                     /locus_tag="PB779_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDE0738711.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="PB779_001176"
     CDS             complement(17084..18157)
                     /locus_tag="PB779_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0738712.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="PB779_001177"
     CDS             complement(18154..18981)
                     /locus_tag="PB779_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738713.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="PB779_001178"
     CDS             complement(18982..19788)
                     /locus_tag="PB779_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738714.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="PB779_001179"
     CDS             complement(19800..20885)
                     /locus_tag="PB779_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738715.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="PB779_001180"
     CDS             complement(20902..21444)
                     /locus_tag="PB779_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0738716.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="PB779_001181"
     CDS             21702..22691
                     /locus_tag="PB779_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDE0738717.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIITFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="PB779_001182"
     CDS             22688..23425
                     /locus_tag="PB779_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HDE0738718.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="PB779_001183"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="PB779_001183"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HDE0738719.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="PB779_001184"
     CDS             23989..24621
                     /locus_tag="PB779_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDE0738720.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="PB779_001185"
     CDS             24706..25353
                     /locus_tag="PB779_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0738721.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="PB779_001186"
     CDS             25358..26341
                     /locus_tag="PB779_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
                     /protein_id="HDE0738722.1"
                     /translation="MRAISIKHPGSVDVLEQIEVPVPKPKQGELLIKVHTAAVNRTDI
                     MKRESVSLKPPYPILGVEVAGEVVENKSDISTFTPGTKVYGLVNLGGYAEYAVMPADR
                     AILLPDTLDYVSAAGISEVFLTAYQTLYWLGKLQEGETVLIHAGASGVGTAAIQLARQ
                     LSHAKIIVTAGSEEKLAFCKELGADELINYKKQDFQEEVRKITEGRGVDVILDFIGAS
                     YWEKNLASIAVDGRWVLIGMLGGTIVPEIDLGVLIGKRVQLLGTLLTPRSDQYKAELA
                     QTFMQKAGPFLENGKIRPIIDRTFQFSAVKQAHEYMEANKNIGKIILKITE"
     gene            complement(26744..28258)
                     /locus_tag="PB779_001187"
     CDS             complement(26744..28258)
                     /locus_tag="PB779_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HDE0738723.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="PB779_001188"
     CDS             28396..29202
                     /locus_tag="PB779_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738724.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="PB779_001189"
     CDS             complement(29377..29946)
                     /locus_tag="PB779_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0738725.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="PB779_001190"
     CDS             complement(30029..32089)
                     /locus_tag="PB779_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HDE0738726.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="PB779_001191"
     CDS             complement(32366..33844)
                     /locus_tag="PB779_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738727.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
BASE COUNT        10255 a         7082 c         5747 g        11034 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagatgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttaccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactgg cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctctttta
//
LOCUS       DAMEEU010000025        32570 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.026, whole genome shotgun sequence.
ACCESSION   DAMEEU010000025 DAMEEU010000000
VERSION     DAMEEU010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32570)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32570)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32570
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.026"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(42..230)
                     /locus_tag="PB779_001192"
     CDS             complement(42..230)
                     /locus_tag="PB779_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HDE0738728.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            500..862
                     /locus_tag="PB779_001193"
     CDS             500..862
                     /locus_tag="PB779_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDE0738729.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            914..2596
                     /locus_tag="PB779_001194"
     CDS             914..2596
                     /locus_tag="PB779_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HDE0738730.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKETPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            2713..4749
                     /gene="recG"
                     /locus_tag="PB779_001195"
     CDS             2713..4749
                     /gene="recG"
                     /locus_tag="PB779_001195"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HDE0738731.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKEFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LLTGSTKAKERRELLEKLEQGEINIVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            4798..5799
                     /gene="plsX"
                     /locus_tag="PB779_001196"
     CDS             4798..5799
                     /gene="plsX"
                     /locus_tag="PB779_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HDE0738732.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            5921..6163
                     /gene="acpP"
                     /locus_tag="PB779_001197"
     CDS             5921..6163
                     /gene="acpP"
                     /locus_tag="PB779_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HDE0738733.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
     gene            6431..7435
                     /locus_tag="PB779_001198"
     CDS             6431..7435
                     /locus_tag="PB779_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738734.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            7436..8380
                     /locus_tag="PB779_001199"
     CDS             7436..8380
                     /locus_tag="PB779_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738735.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            8380..9342
                     /locus_tag="PB779_001200"
     CDS             8380..9342
                     /locus_tag="PB779_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738736.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            9369..10283
                     /locus_tag="PB779_001201"
     CDS             9369..10283
                     /locus_tag="PB779_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738737.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            10309..12090
                     /locus_tag="PB779_001202"
     CDS             10309..12090
                     /locus_tag="PB779_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0738738.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            12438..13124
                     /locus_tag="PB779_001203"
     CDS             12438..13124
                     /locus_tag="PB779_001203"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HDE0738739.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKECHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            13144..16725
                     /gene="smc"
                     /locus_tag="PB779_001204"
     CDS             13144..16725
                     /gene="smc"
                     /locus_tag="PB779_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HDE0738740.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIEAALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            16734..17543
                     /locus_tag="PB779_001205"
     CDS             16734..17543
                     /locus_tag="PB779_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0738741.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            17554..18552
                     /gene="ftsY"
                     /locus_tag="PB779_001206"
     CDS             17554..18552
                     /gene="ftsY"
                     /locus_tag="PB779_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HDE0738742.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            18739..21006
                     /gene="gshAB"
                     /locus_tag="PB779_001207"
     CDS             18739..21006
                     /gene="gshAB"
                     /locus_tag="PB779_001207"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HDE0738743.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKKYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(21095..21547)
                     /locus_tag="PB779_001208"
     CDS             complement(21095..21547)
                     /locus_tag="PB779_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HDE0738744.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKNNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            21697..22647
                     /locus_tag="PB779_001209"
     CDS             21697..22647
                     /locus_tag="PB779_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDE0738745.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            22640..23599
                     /locus_tag="PB779_001210"
     CDS             22640..23599
                     /locus_tag="PB779_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HDE0738746.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            23596..24351
                     /locus_tag="PB779_001211"
     CDS             23596..24351
                     /locus_tag="PB779_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738747.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            24374..25327
                     /locus_tag="PB779_001212"
     CDS             24374..25327
                     /locus_tag="PB779_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0738748.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(25971..26267)
                     /locus_tag="PB779_001213"
     CDS             complement(25971..26267)
                     /locus_tag="PB779_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HDE0738749.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            26622..26978
                     /locus_tag="PB779_001214"
     CDS             26622..26978
                     /locus_tag="PB779_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDE0738750.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            26988..27887
                     /locus_tag="PB779_001215"
     CDS             26988..27887
                     /locus_tag="PB779_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HDE0738751.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            28404..29135
                     /locus_tag="PB779_001216"
     CDS             28404..29135
                     /locus_tag="PB779_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDE0738752.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            29280..31307
                     /locus_tag="PB779_001217"
     CDS             29280..31307
                     /locus_tag="PB779_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDE0738753.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRINIPVENQRIGTFEGKLSWILADVPGN"
     gene            31415..32512
                     /locus_tag="PB779_001218"
     CDS             31415..32512
                     /locus_tag="PB779_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDE0738754.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
BASE COUNT        10863 a         5669 c         7005 g         9033 t
ORIGIN      
        1 aaaaaaccgt tcactatctg aacggtccaa gtatcattca attaaacgcg ttcaactttt
       61 cctgatttca aagcacgagt tgacacccaa acttttttag gttttccgtc gaccataacg
      121 cgaacttttt gtaagttagg tttaacagta cgttttgttg agttcatagc gtgtgaacgg
      181 ttgtttccac tttttgtctt gcgacctgta aagtaacaaa cttttgccat ggtaatttcc
      241 tcctttgcct tgatttggag caatagaata attcagctca taccagacta acatatcata
      301 tagaatggaa atttgcaagt acattttcat agatacaatt gacaattgag aagaataatt
      361 gtaaattaaa caaggttata cctgaaattt tgcaaggttt ttgagtactt tgggtaactg
      421 ccttttattt caagttgcgc tatgataaaa tatgatagaa gaaaaatggg agttttttac
      481 ccgttaagga ggctcattca tggctgtaaa aattcaaacg tcagctggaa ccattgaaat
      541 taccaatgat gtaattgcaa cagttgttgg tggcgccgcg acagatgtgt tcggtgttgt
      601 aggaatggcc agcaaaaatc aaattaaaga taatattact gagattttgc gtaaagaaaa
      661 ttactcaaga ggagtagttg tccgccaaga agataatggt attgctgtag atgtttatac
      721 gattatcagc tatggtacga aaatctctga agtttcccgc aacgtccaag aaaaagtgaa
      781 atacaatcta gaggcattat taggcgtaac tgccaattca gttaatgtct ttgtacaagg
      841 tgttcgtgta ctgccagact aggcaggaga ctggctggta actcagcagt cgatctgaag
      901 gaggattatc taggtgagtg taacagaaat aagtgcaagc cagttccagg aaatggtcca
      961 ggcaggtgcg aatcgtctgc aagtaaatgc agaatacgtc aattcattaa atgtattccc
     1021 tgtgccagat ggcgatacgg gaacaaatat gaatctatct atgactagtg gagctaaggc
     1081 agtagtagat tcaacctcag aaaaagtagg agaattagca gcaatgcttt caaaaggatt
     1141 gctgatgggt gcgcgcggaa attccggcgt tattttgtct caattgtttc gtggattttc
     1201 taagcaaatt ccagatgttg tctcattaaa tgcttccgat cttgctgcag ccttcactca
     1261 tggagttgaa actgcgtata aagcagtaat gaaaccagta gaaggaacga ttttgacagt
     1321 agctagagaa gcagcgaaag ctggagaaaa gaaagcaaaa agtactgatg atgtcgttga
     1381 agtaatgaca gctgttgtaa aaggggcaaa gcgtgcttta gctaaaactc cagacttgct
     1441 tccagtccta aaagaagtcg gtgtcgtaga cagtggaggg caaggactgc tgtttgttta
     1501 tgagggcttt ttaagtgcat tgaatggaga attccaagcg gatgaaacat atgaaccttc
     1561 tccagcagaa atggatgata tggtcaatgc agaacatcat cgcagtgtcc aaggtcaaat
     1621 ggcgacagaa gatatccatt ttggttactg tacagaaatc atggtaaaaa tcggagaagg
     1681 acctacagtc gatagtacat tcgattacga agaattccgt aactatttag atggtatagg
     1741 agattcttta cttgtggtca atgatgacga gatcatcaaa gtccacgtgc atacagaaaa
     1801 cccaggagaa gtcttgaatt atggacaaaa attcggttca ttagtcaaaa tcaaagtcga
     1861 caacatgcgc ttgcagcatg agacgatttt ggaacacgat gaagaagtga acgagtttgc
     1921 gaaaaaagaa acaccacgta tcccgtatgg tatcgtagcg atcgctgctg gtaaaggcgt
     1981 ccaagagctg tttgaaagtt taggcgctaa ttatgttatc agtggtgggc aaacaatgaa
     2041 tccaagtacg gaagacattg ttaaagcgat tcaagaagta aacgcagata aagtgattgt
     2101 cttgccaaac aataagaaca tcttcatggc agctgatcaa gcagcagaag tagcagatat
     2161 cccagtagca gttgttcctt caagaacgat ttcccaagga ttgacagcta tgctttcatt
     2221 caatgatcaa gcttctttag aagaaaacaa agaaacgatg acagaaatgt tgtctagcgt
     2281 tgtgagcggt caagtcactc acgcgatcag agatacctca attgacggtg tagagatcaa
     2341 agaaggagac tttttgggca tgatcgatgg aaaaatcctg atctctaacc cagatatcac
     2401 agcaacagcg ttaagtacac tagaacaaat gatcaatgag gacacagaga tcgtaacgat
     2461 cttggcaggt gatgaaggaa cagttgaaca agcaaatgaa tttgctgaga aactaacaga
     2521 aaaacatcct gatttggaaa tcgagatcca ccaaggagat cagcctgtct atccttatct
     2581 attttctgct gaataatttc tgtgtcagaa tatctttcta acacagtatt cattcataaa
     2641 aggccttcgg ttagtgatca ggtatgatcg ctgaccaagt cctttttttg ttaagggagg
     2701 gaggaaaaat ttatgcgttc tttagatgat ccaatcacta tgctggcagg agtcggagaa
     2761 aaaagagcag ctagtcttgc cagcttgggc atccaaacga ttgaagactt actgacttat
     2821 tatcctttcc gctacgaaga tattcaggaa agaaatctaa acgagatcca agatcaagaa
     2881 aaggttactt tgaaaggaat cgtagtctcg cctcctgtga tgaatcgatt tggttataaa
     2941 aaaagccgat tgcaatttcg tatgatgcaa gaacatgatg tgttcaacgt ttcttttttt
     3001 aatcaacctt atctaaaaga aaaagtcatt ttatcggagg aaatcgccgt atacggtaaa
     3061 tgggatgcaa agcgtaaagc attgaacggg atgaagattt taggttctca aacaatggat
     3121 gacttttcgc cgatatatca cgtcaacaaa tcaattcgtc aaacgacatt agttgatcta
     3181 atcaaaaaag ggtttcaaga atacggcaca ttgattgaag aaaatctgcc aaacaacctt
     3241 gtggagaaat atcgactgct tgaccgagct tctgctgtaa gaagtatgca ttttccaaaa
     3301 gaccacgaag aaaaccatca agccaaacga cgtgtcgttt ttgaagagtt ctttttattt
     3361 caaatgcgtc ttcaaggatt gaaaaaagca gaaaaagcag aaacgaatgg tttggagatc
     3421 ctttatgatg tccaaaaatt gaaagaattt actcaaaagc taccttttga actgacaaat
     3481 gcacaaaaac gtgtaacgaa tgaaatctgt cgggatcttc gcagtccgca gcatatgcag
     3541 cgacttttgc agggagatgt aggtagcgga aaaacagtgg ttgccgcgat tgcgttatac
     3601 gctaccgtta cagcaggttt ccaaggtgcg ttgatggtgc ctacagaaat cttggcacaa
     3661 caacatatgg aaagcttgca acagctgttt gatcccaatg aagtaaccat cgcattgctt
     3721 acggggtcaa cgaaagcaaa agaacgtcgt gagctccttg aaaaactaga gcaaggggaa
     3781 attaacatcg tgatcggcac acatgcattg atccaagatg gagtcgaatt tcagaattta
     3841 ggtctagtta ttacggatga gcagcaccgt tttggcgtga accagcggaa agtacttcgt
     3901 gaaaaaggct ggcgaccaga tgtcttattt atgacagcga ctccgattcc tagaacatta
     3961 gctattacag catatggtga gatggatgta tctatcattg atgaacttcc agctggacgt
     4021 atcccgatcg aaacacgctg ggtaagaaca cctcaattgg acagtgtact ggattggacg
     4081 aaaaaagaac tggcaagagg acatcaaatg tatgtcatct gtccgctgat tgaagaatca
     4141 gaagcattag atgtaaaaaa tgcagtggaa atctatgaaa aacttcgtga actatttgca
     4201 ccaaaatatg aagttggctt gttacatggt aaaatgaaga atcaggaaaa agaagtaatc
     4261 atggaagcct tcaaagacaa ccagatgcag atattagttt cgactactgt aattgaagta
     4321 ggggtaaacg tgccgaacgc gaccgtcatg ctgatcatgg atgcggatcg atttggattg
     4381 gcacagctgc atcaacttcg tggacgtgtt ggacgcggaa gtgatgcttc ctactgtatc
     4441 ttagttgcta atcctaaaaa tgaactaggt gtggaacgga tgaaaatcat gacagagacc
     4501 accaatggtt ttgtactaag cgaaaaagat ctggaattac gtggtcctgg tgaagtattt
     4561 ggcttccgtc aatctggtct gcctcaattt gcgattgctg acttggtgac ggatggaaat
     4621 gttttggagg tagccagaga agaggctgca gccctttggc agataaagga ttggcagatg
     4681 cttcctgagt atcagccttt agcgcaaagc ctccaaatag aaaatcagga taatcgttat
     4741 ttcgattagc agactgtgct atactttata ctgatgacgg aaaaaggagt ggaaacaatg
     4801 aaaattgccg tagatgcaat gggcggagat cacgcacctc aagcaattgt agaaggcgtg
     4861 gctttagcgc agcaagattt tccagaagta gaattcttac tttacggaaa agaagcagaa
     4921 atcaagaaat acttaacaaa tgaaaaaaac atcacgatta tccatacaga cgaaaaaatc
     4981 aatagtgatg atgagccagt aaaagcaatt cgacgaaaaa agactgcatc aatggtcctt
     5041 gctgcacaag cagtgaaaaa cggtgaagca gatgctgtat tttcagcagg gaatacaggc
     5101 gcgctactag cagcagggtt gttcatcgta ggacgtatca aaaatatcga acgccctggc
     5161 ttgatgtcta ccttgccagt agtagggaaa gaaggtgccg gtttcgatat gctggatctt
     5221 ggcgctaacg cagaaaacaa accagaacat ttgttgcaat acggtatttt aggttctttt
     5281 tatgcacgta aagtccgagg tatcggacgt cctcgtgtcg cactcttaaa caacggaaca
     5341 gaagcaacaa aaggtagtga agtgacgaaa aaagcctatg aactccttca gaatgaaaca
     5401 agcttgaatt ttattggaaa cgtagaagct cgtgagctac tcaatggtgt ggctgatgta
     5461 gtggtcacag atggatttac aggcaacgct gttttgaaat ctattgaagg aacagcaatg
     5521 aatatgatga atctattaaa atctgctatt ctaaatgaag ggatcaaagg aaaaatgggc
     5581 gctatgcttt taaaagacgg cttacgttct ttgaaagcag aaatggatta ttccaaacat
     5641 ggcggtgccg ttttgtttgg cttgaaagca ccagtcatta aaactcatgg agcaacaggc
     5701 cccgatgctg ttcgctatac gatccgccaa atccacacaa tgcttgagac agatgtagtt
     5761 ggacaattag tcgaacaatt tgaaaaaagc gaagaatagt atttggatat ctgaagcaat
     5821 ccgttccatt gaaaaaaagg tggacattcc tgaaaaatgc cagtaaaatt agccatggtg
     5881 taggtaattg acaagtgtat gattcttgga ggtgaaaaag ttgactcgcg aagaagtatt
     5941 taacaaagta gcgaaaatta tttcaaatca ttttgagata gataccgata aagtgacgga
     6001 tgaattgaac atcaaagatg atttaaaagc tgattcaatt agtattatgg aattcgtttt
     6061 agagcttgaa gatgaattcg gtacggaaat ttcagatgaa gacgctgaac aaattgaaac
     6121 agtcggtggc gcagtagatt atatcagcag ccatcttaaa taatttcaaa taaaagcaaa
     6181 gaaggataaa aagctgcata cagcttttta tccttctttt tttaatcttt ttgacacgta
     6241 aaagtcattt ttctgataat tctggcgata aacagaaatt atgttgcaaa gtaaagcgat
     6301 tttctatata attattaata attcattaca caaagataag aataaccttt gttataaaac
     6361 gctttattct gtgtaatgtc cttttttatt aagaaaaact tccatttagg aagcagagag
     6421 gggtattcga ttgtccgata accaattatt agaagttcag aacctacata caggattccg
     6481 actcaaagat gactattacg atgcagtaga tgacgtttca tttactttag acaaaaacga
     6541 gattttagca atcgttgggg aatctgggtg cgggaaaagt accttggcta ctacgattat
     6601 gggattactt gatcctaata acacaaaaat tacaggtgag attttatata acgatctgaa
     6661 tttaatcgac ctgaacgaaa cgctctataa taaaatccgc ggaaatgata tcggaatgat
     6721 tttccaagat ccgttgtctg cattaaatcc tctcatgaga atcgaagacc agatcaaaga
     6781 aggactttcc tatcacacaa agatgaatgc agaacagcgt caagctcgtg cactagaatt
     6841 gctagaacaa gtagggattc ctaatcctgc gagagttgga cgccaatatc cccatgaact
     6901 atcaggcggt atgagacaac gtgtcatcat cgcaatcgca atcgcctgca aacctccaat
     6961 cgtcattgca gatgaaccga cgacagccct agatgtaacc atccaagcac agattcttga
     7021 tttactgaaa gaccttcagg aagaaacaaa aacagggatc atcttgatca ctcatgactt
     7081 aggagtcgta gcagaaatgg ctgatcgagt ggcagtgatg tatggcggac agttcgttga
     7141 agtagcaggt gtaaaagaac tgtttgatca tcctaagcat ccttatacac gctctttact
     7201 gaactctata ccacaagaag gaaatcatga tgcagaactc catgtgatcg aaggtgtcgt
     7261 tccttctctg aaaaacatgc ctcgtaaagg ttgtcggttt gcaccacgta ttccatggat
     7321 accagcaagc gatcatgaag aagagcctat ccttcatgaa gtcgcaccga accacttggt
     7381 acgttgctcc tgctataagc atttccactt tagagacgaa aaaggagagg tgtagatgac
     7441 agaattaatc acaatcaaag acctgaaagt tcattaccct attcgcagtg gattcttcaa
     7501 tcgagtaacg gatcatgtat atgctgtaga tggtgtggat tttattatcg aaaaaggaaa
     7561 gacatatggt ttagtgggag agtctggctc tggaaaatct actacgggaa aagccgttgt
     7621 gggattagaa aaggtaacag ccggacaaat catgtatgaa ggaaaagatg taacgaagcg
     7681 aagcaaccgc aaaaaaatgg gttataacaa ggatgtgcag atgatcttcc aagattcaat
     7741 gtccagtttg aatcctaaaa agcgagtgtt ggatatcatt gctgaaccca tccgaaattt
     7801 tgaacggtta agcgatcaag aagaaaagaa aaaggtaaaa ggactgctag atatcgttgg
     7861 gatgccggaa gatgcgctat ataaatatcc tcatgaattt tcaggcggac aacgtcaacg
     7921 tctaggagta gcccgtgctg ttgctaccaa tccaaaactg atcgtagccg atgaacctgt
     7981 atctgctctg gatctatctg ttcaagcgca agtattgaat ttcatgaaac gaatccagca
     8041 agaatacggc ctcagctatt tattcatttc acatgattta ggtgtagtaa aacacatgtg
     8101 cgacaatatc gcaattatgt acaaaggtcg atttgtagaa atcggtacaa gagaagacat
     8161 ttataatgac ccgcgacata tctatacgaa acgtctgctt tcagctattc cgcaaatcga
     8221 tgtagaaaat agggaaagcc acaaagaaaa tcgacgaaga gtagaacaag agtatatcca
     8281 aaaccaaaaa gaatactatg atgcgactgg tcgagtctac gatttgcgta cgatcacaac
     8341 tacacacaaa gtggcgttga aagatggagg tgcaagctaa tgtggaaaac gattctgcga
     8401 cgtgttttat tgatgatccc gcaagttatt attttaagtg ttctgatctt cttattagcc
     8461 caagcgatgc cgggggatcc atttaccggt ttgatcaatc caaatcagga tccggcagtg
     8521 atcgaacaga tgcgacaagc agctggcttg aatgacccat ggtatgtcca gtacttccgt
     8581 tggatcggaa atgctttgca aggcgatttt ggtcaaagtt tcttatacaa acgctctgtt
     8641 gctgacttga tcggcgaacg gatcatcaac actttatatc tatcgatctt gacagttgtc
     8701 cttacttatt tgattgctgt gcctctgggg atgcttgctg gccggtatca aaattcaatc
     8761 ttggataaga ttgtcgtaat ctacaacttc tttagttttg ctgttccttt atttatcttc
     8821 ggcttgatca tgctatttgt ttttggttat cgtttaggct ggttcccaac aagtggatca
     8881 caaacactag gtttgcaagg tggatttatc actcaatgga tagaccgttt gaaatatatt
     8941 ctgttaccat caattaccca agcatttttg gcgactgccg tcacaatcca atatctgcga
     9001 agtgaagtaa tcgattcgaa atcgctcgat tttgtcagaa cagcccgttc caaaggggta
     9061 ccgacgaata aagtattcag tcgacatatt ttccgaaatg cagcgttgcc gatggcttct
     9121 caaatggggt atgaaatcac ttcgttgatt gctggttctg tagttatcga aaagattttt
     9181 ggttatccgg gagtcggaaa actatttatt gattccatcg gccaacggga ctataccgtg
     9241 atcacatcct tagtattgat tttaggaatc gcgacgctag tggggacatt actttcagat
     9301 atcatcatga gtatcgttga cccgcgtatt cggattcaat aaaaccaatc agaaaggaga
     9361 atggatcgat gagtgaaaaa aacaatacag cagttcaaga aagtattcct cctatgggga
     9421 tacgaatgat tgctcgagaa tttaaaaaag ataaaattgc tattttttca ttaggtttgc
     9481 tagtggtttt attattagtg atctttatcg gtgcgatgct gaccgatcaa gacaaagtga
     9541 tgtatgttag tatcttcgac aaatacgctg caccaggaac agtttcgaca caaggacaaa
     9601 agttcattct gggagcagat gaaggcggac gtgatgtatt aggacaattg atcataggtg
     9661 ctagaaactc tgttacgatc ggatttgcga tcacgatcct tacttcgatc atcggggttg
     9721 gattagggat catctctggc tactacggag ggatcattga caacatcttg atgcggatcg
     9781 ttgattttat catgattcta ccgatcatgc tgatcattat cgtcttcgta tcgattattt
     9841 ccagatacaa tgtctggtcc tttatattca tcatgagtgc attttattgg gtagctaaag
     9901 cccgattatt ccgaagcaag acattatctg aagcaagaag agattatgtc agtgcctcaa
     9961 aaacaatggg aaccaatgat tttaaaatca tgttccgcga aatcatgccg aatctaagtt
    10021 cattaatcat tactaatttg acgatgaact ttgcggcaaa catcggtatc gagacaactt
    10081 tgactttctt aggtttcggc ttgccggcaa atgtacctag tttaggtaca ttgatcggtt
    10141 atgcaagtaa cggagaagtc ttagtgaatc ggcaatggat ctggttaccc gcatcaatcc
    10201 ttattttagt tttgatgttg agtatcaatt atgttggaca agcattcaag cgttctgcag
    10261 atgcgcgcca acggttaggc tagtatagaa gcgaaggggg aaataggaat gaagaaaacg
    10321 atttttggat ttgcagcgct gatgtctgct gtcgttcttg cagcatgcgg gggcggaggt
    10381 acagatacct ctggaaacaa ctctggaggc aacggcaata acaaagagga attaactttt
    10441 ccaattgcaa caaaaaataa tgatgatgca atcgaagacg gcgaattaga agctgcggtc
    10501 gcaacggaca gtcagtttaa aggattgttc cagtgggagt tttaccaaga ttcatatgat
    10561 gcagctttta tggctccttc tcatgaaccg ctatttgcaa acgatgacga tttcagaatc
    10621 acagacgacg gagctgcaac gcttgatcta gatgaagata cgaaaaaagc gacaatcaaa
    10681 gtaaaagaca acgtcaaatg gtcagatggt gaagatgtaa cggcggacga tgtgattttc
    10741 ccttacgaaa tcattgggaa taaagattac actggtatcc gttatgacga cactttccgt
    10801 aacatcgtag gtatggaaga atatcatgat ggaagtgccg acacaatctc cggaatcaaa
    10861 aaaatagacg acaaaacagt tgaaatcgaa tataaagaag taaacccaag catgcttcaa
    10921 tcgggtggtg gtatctggtc atatgcagca ccaaaacata cgttagaagg tgtagcaatc
    10981 aaagatatgg aatcaagcga tcaagtacgt aaaaatccag tgacttttgg cccttattac
    11041 atgagtaata tcgttgcagg agaatcagta gaatacttgc caaacgagca ctactggaat
    11101 ggtacgccta aattgaaaaa gatcacgatg aaatctgtac cgatggcaag tgcaactgaa
    11161 gcattgaact ctaaattata tgatatgatt ttccaaatgc caacagatac ttacgatacc
    11221 tataaagaaa ttgctggcta tacaaactta ggccgtgaac aaacttctta tacttatcta
    11281 ggattcaagt taggtaaatg gaatgcagat acaaagagtg tggaatacaa tccagattca
    11341 aaaatggctg ataaatcatt acgtcaagca atgggctatg cattagataa taatgcagta
    11401 ggtgaacgtt tctatgcagg tttgagaagc aatgcgactt cattgattcc tccagtattc
    11461 cagtcatacc atgatgatga gatgaaagga ttcacacaag atctagacaa agcgaaaaaa
    11521 ctattagatg atgctggcta caaagatgtg gatgacgatg gtttaagaga agacaaagat
    11581 ggaaataaac taacaatcaa ctttgcttcg atgtccggtg gggaaacagc gcaaccattg
    11641 gcagattact atatccaaca atggaaagaa attggtttgg atgtccaata cacaacaggt
    11701 cgtctgatcg aattcaattc tttctatgat aaattagaaa acgatgatcc tgaaattgat
    11761 gtttaccaag ctgcttggaa tacaggaact gatccaaatc caagtggact atggggacca
    11821 aatgctgcgt tcaactacac tcgttatgaa tcagaagaaa atacaaaatt gatcaacgat
    11881 atcagttcaa gcaaagcatt tgatgaagag taccaaaaag aagcatatca aaaatggcaa
    11941 caatatgcat ttgaagaagc atttgcgatt ccaacgttgt tccgtaatga agtattgcca
    12001 gtcaacgacc gtgtcaaaga ctgggattgg tcttatgatg taccaaaccc atgggcaaat
    12061 gtttctgtta cagcagattc acgttcataa tcactaaaaa tgaccgaaaa agggcgatgt
    12121 cctttttcgg ttttttgata tttttctgtt tatttctcta atattcaggt caaggcgctg
    12181 atttcatgac ttctccaata aacggtgttc aaagtccagt ttctcggtat taagtcaaat
    12241 ttatgcaaaa atatggaaag ccattttcac aaaatttttt cttcatactc gaaactaaac
    12301 gaatttttca caacttctcg tcaatcacta ggattattaa agctttactt accttttgac
    12361 cgaaccattt caaatttgac aaaaaaccag tataataagg aagtatcgaa aaaatatcca
    12421 taaaaggaat gtggaaaatg gacaaccagc tgacaaaaga actaaaagaa aactataaca
    12481 tcgtttttca cgatctaaat ttgcttgaac aagcttttac ccattcatcc tatgtgaatg
    12541 agcatcgcaa tctgcaatta tcggataatg agcgacttga atttttagga gatgccgttt
    12601 tagaactgat ggtttctcag tatttattcc gtttatatcc tcatttgcca gaaggaaaat
    12661 tgacaaaaac acgagctgcg atcgttcgcg aagacagctt gtcgaaattt gccaaagaat
    12721 gtcactttga tcaatatgtt ttgttgggca agggagaaga gaattcagga ggacgtacgc
    12781 gaccagcatt gctttgcgac ctattcgaag cttttttagg cgcgttatat cttgaccagg
    12841 gattcgacac gacccatgca ttcatcgaaa aagtgatttt tcctaaagtc aaagcaggtg
    12901 ctttttcaca tgagatggat cataaaacaa aactacaaga agtcttgcaa aaatcaggtg
    12961 atgtatcaat cgaataccga ttgatcaatg aagaaggtcc agctcatgaa cgagtatttt
    13021 ggatcgaagt ttatgtagat gatcaattga ttggcactgg acaagggaaa tcgaaaaaat
    13081 tagcagaaca agctgcggcg gaaaatgcat tggcagcact gtaaaagtaa gtgagggaaa
    13141 gctttgtatt tgaaacgaat tgaaatagcc ggttttaaat catttgcaga caagacagtc
    13201 attgattttg aaaatagcgt cacagcagtg gttggaccaa atggcagcgg aaaaagcaat
    13261 attacagagg ctatccgctg ggtattagga gaacaatctg ctaaaagtct gcgaggcgga
    13321 aaaatgccgg atatcatctt tgccggttcc gatacccgta agcagctgaa tattgcagaa
    13381 gtcacagtga ttttagacaa tagtgatcat tatctgccat tggagtacaa tgagatcagt
    13441 gtaacccgcc gttatcgacg gactggggaa agcgagtttt tcatcaataa acaaagctgc
    13501 agattaaaag atatccaaga attgttctta gattctggat taggaaaaga atcgttctca
    13561 atcatttctc aaggaaaagt agaagcgatt ttcagtagta aaccggaaga ccgtcgtggg
    13621 atctttgaag aagcagctgg tgtcttgaaa tacaagcagc ggaaaaagaa agcagaacag
    13681 aagctttttg aaacagaaga caacctcagc cgcgtccaag acatcatcca cgaattggaa
    13741 gaacagttaa ctcctttggc cgcccagagt gaggcagcaa aggagttttt acggctaaaa
    13801 gaaacactga ctcaaaccga tgtctctttg atggttgctg aaatcaagac agcaaaaaaa
    13861 gattgggaca acaaacaagc acagcttgcg aaattcaatc tagaattagg caaactatct
    13921 gagtcgatcc aagaacaaga atccattttg gcgaagcagc gtaaagaaaa tgcgcaagcc
    13981 gatcgtctga tcgaaaaaaa tcagcaagta ttattagatc tttcggaaaa actgaagcag
    14041 acagaaggac aaaaagatgt tttgcaggag cggacaaagc atacacaaaa aagctcgcaa
    14101 gaatatcaaa cttcattagc agaagcacaa aaaaaggtta aacattttga aaagcttcaa
    14161 gaaagcttga tgaaagcagc agcagaaaaa gaaacagaga tccaaaaagc tgaagcaaat
    14221 ctcataaaaa cacagcaaga attagaaaaa taccaaaaat caacgaaaga attattggca
    14281 gaattaagag atcaatatgt tgatttgatg caagaacaag cagctgtagg aaacgaactg
    14341 aagtatctag aacgtcaata tatacaagaa acagcaaaaa gcaagcagac gttagccaag
    14401 caatcggaag tagaagcatc agtagaccga ttgatcttac aaaaagaaga attgacacaa
    14461 aagcaggcgc agctaaaatc atctttaact gaaacaaaag agaagttaga aatgatccaa
    14521 caaaacggga aaaagttcca agaagcatta gcaaaagaac agcctaaaat gtatcaatta
    14581 atgaatcaag tccagcagct acgtgctcgt aagaaaagcc ttcaagaaat ccaagaaaac
    14641 tattttggtt tttaccaagg ggttcgattg gtcttgcagc ataaacagca gctttcgggt
    14701 attgtcggag cagtggctga actgatcgat gttcctgcag atttcacgtt agctatcgaa
    14761 gcagctttag gtggggcagc ccagcatgtc atcgttgaaa atgaaaaaga tgctcggcaa
    14821 gccatcacgt atttgaaaca gcaaagagga ggaagagcaa cattccttcc actgacgaca
    14881 atcaaaccaa gacaattacc ggctcatata ttgacacaag cagcagctgt agaagggttt
    14941 atagggattg ccagtgaaca agtcagttat cccgatcaaa tccaaactgt ggttcaaaac
    15001 ctgctaggaa cgatcctttt agccaaagac ttaactagtg ccaatgcaat cgcgcaaacg
    15061 atccgctatc aatatcgagt ggtttcctta gaaggtgatg tgatgaatgc cggaggatcc
    15121 atgacaggtg gagcgaataa acgaggaaac caaggcagtt tgtttgtaca aaatcaagaa
    15181 ttgaaacagt tgactagtga atttgaagaa gcagataaac aactccaagc acaagaaaaa
    15241 aaagttcagg agctgcaaca agaaacagct cgtttagccg aagaacaaga agttttgcgt
    15301 acacgaggcg aacaattacg ttttgaagaa caagaagcga caaatcagct acaaaacatc
    15361 ataaatgaac ttgaacgttt tgaaaaagaa aagcaaatct caacttttga gacacgtgaa
    15421 ctgcagcagt ttatcgaaga ttacgaaaag caaacgaacg aattgaaaga caaacaaaca
    15481 gatcttgaat cgcaacgaca aaaaatcgac gaagaaatca aatcgttaag tcaagaaagc
    15541 gaccagatgg aagccagaag agcacaagta caaagtcaaa aagcacaaga acaagcagat
    15601 cttgctgtct tgaaagagca gtttaatcat ctgcagatcc agctccgcgg tgcccgagtc
    15661 caaaaagcag aggcaaccga acgtcaagaa gcgatagaaa agcagttggc gacattgaca
    15721 gcagactttt ctgatcatga agtcacagaa gaaagtttgg aaaaacaaat taacgaatta
    15781 tctgctcagc gagaaacatt aaaagccgag ttggcaaaag ccaaagagca gcgagataga
    15841 aggcaaaagg agatcgataa gcttgaagca gtcttggcag agcgtaatcg tgagcaaaaa
    15901 gcacgactgt cggaacaatc caaattagaa gtccaaaaag accgagctga aatgatttta
    15961 gataatcatt tgacctatct gcagtcagaa tatcagctga catttgagaa agcttcccaa
    16021 gactatcaag aaacaaccga tatcgaagac agtagaacaa aggtttcatc cttaaaagaa
    16081 cagattgaaa aactgggacc agtaaactta aattcaatcg aacaatacga acaagtcagt
    16141 gaaagacata cattcttagc aacacagcga gatgatctgt tagcagcgaa aaaccaattg
    16201 tttgaaacga tggatgagat ggatgatgaa gtgcggacaa gattcaaaga agtatttgaa
    16261 gctatccgtc aagaattcaa aattgtcttt ccaaatatgt ttggcggcgg taaagctgaa
    16321 ttagtactga cggaaccaac tgatttgctg aaaacaggta ttgagattga agtacaacct
    16381 cctggcaaaa aactgcaaag tctaagtttg ctttctggag gagaacgagc acttacagcc
    16441 atcgcgttgc tcttttccat tatccgtgtc tgtcctgttc cgttttgtat cttagatgag
    16501 gtagaagcag cgttagatga agccaacgtg aaacgttttg gtcgttactt gagcgatttc
    16561 caagatgaca cacaatttat cgtagtcaca caccgcaaag gaacgatggt cgcagcagat
    16621 gtactgtacg gagtgacgat gcaggaatcc ggtgtatcaa aaatcgtttc tgtacggatg
    16681 gaagatatca atgaagaggc gaaaatcaac gaaacgaaag tgtaggaacg aaaatgatca
    16741 aattagtagc aatcgatttg gacggtacat tattaaatga acaaaagctg atttcagatg
    16801 agaataaaca agcattagca caagcaaaac agcaaggggt caagatcgtt ctatgtacag
    16861 gacgcccctt agctgcgatg gcgcattatc tgcaagaatt aggactggta gatgaaggtg
    16921 actacagcat cactttcaac ggcggtttgg tacaaaaaaa tgatactggt gaaatcatgg
    16981 aaaagaaagt gatggaagta tcagatatcc aacgcttata caaactggct cagcaattgg
    17041 atctgccact agatgttttg tctgacaatg tggttttaca gctgcctagt gccccaagga
    17101 agcaatcctt gtacaatgtg ttgaataagc tgctgcaatt ccaaccagcg gatataagcg
    17161 atattacaga tgaatttgtg cttaataagg cagtaatcgc ttatgaccaa gaagaattag
    17221 atcctaaaat caaagaaata ccagcagaat tccatgaaat gtatgagatc atcaaaacaa
    17281 gaagtatgct tttggaattt atgccaaaag gtgttacaaa agcttatggt atttctttat
    17341 tggcaaaaga tcttggtttg aaacaagaag aaatcatggc gatcggtgat gaggaaaatg
    17401 atttaccgat gatccaatat gctggactag gcgtagcgat ggagaatgct gtgcctttcg
    17461 tcaaagaagc agcagatttc gtgacagcca gcaatgaaga aaatggcgta gccaaagtga
    17521 tccaaaaatt tgtattagag tagggggagt caaatgggat tttttgataa aatcaagcgt
    17581 gcttttactg gcgaagagaa aacagaagaa gttgaagtac aggagaagta cgacaagggt
    17641 ttagaaaaga cgcgtaaaac atttggtgaa cggatgaatg agttgtttgc caattttcga
    17701 acagtcgatg aagacttttt tgaagaatta gaagaaacac ttatcggtgc agatgtaggt
    17761 tttgaaacag cgatacgaat caccgaagca ttacgtcaag aagtgaaact cagaaatgcg
    17821 aaaaaatcgg cagaagtcca aaatgcgatc atcgagaaac ttgtggatct ctatgaagcg
    17881 gaaggaatca atgaagtaaa tgaactaaat atccaagaag acggactaac agttattttg
    17941 tttgtcggtg ttaatggtgt agggaaaaca acaagtattg gtaaacttgc ccatcagttc
    18001 aaaaacgaag gtaaaaaagt attgatggca gcagcagata ccttccgcgc tggagcaatc
    18061 gaccagttag ttgtctgggg cgaacgcgct ggtgttgaag ttgttcgtgg caatgcagga
    18121 ggcgatccag cagctgtcgt attcgatgct ttggaaagag caaagacaga gcaggcagat
    18181 gttttactag ttgatactgc aggccgactg caaaataaag tgaacttgat gaacgaatta
    18241 gaaaaaataa aacgagtaat ccagcgggaa ttaccagaag caccccaaga aacacttctt
    18301 gtattagatg caaccactgg tcaaaacgcg atggttcaag caaaacaatt caaagaaaca
    18361 acagatgtga ccggtcttgt tttgacaaaa ttagatggta cagcaaaggg cggtatcgta
    18421 cttgctatcc gtaatgaatt gcatttacca gtgaaattgg tcggtcttgg tgaaggaatc
    18481 gatgacttgg agccgtttga tccaaatgat tttgtcgttg gattgttcaa aggattacta
    18541 aaagaagaat aacccatgtc taaaaagcag gagctgtgac aaaagttgca gctccttgtt
    18601 tgaatgattg tttttaacat agctgtgttt ttgatgcctt catttttata cttatttgta
    18661 agcggttctc aaacaatttc gttctttttc ttagactttt tgattataat tagattcata
    18721 tgaattggag gtcacttaat gatgaatttt aagcaattat tattgcatgt caatgcgcgc
    18781 ccttttatcg accaagctcg atttggtata gaacgggaag gacagcgggt tgatcttgca
    18841 ggaaatctag caaaaaccga tcatccagca atctttggcg atcgatccta tcacccctat
    18901 atccaaacag attttagcga aacacaaaca gagatgatca cccctgttac cgattctatt
    18961 cccgaattat ttcagtatct cgctgctgtt tatgatgtga ctgctcgttc tataccgaaa
    19021 gaagagatga tctggccatt aagtatgcca cctgccttac cggaaaaaga cgaagagatc
    19081 attattgcaa aattaaaaaa tttcgaagat gtcttgtatc gacgttattt agcaaaaaaa
    19141 tacgggaagc gaaaacagat ggtaagcggt attcatttca attttgaatt tggcgatgag
    19201 ttgctaagaa cattgttcag ccatcaggaa gaatttcaag atttttccga attcaaaaca
    19261 gaactttatt tgaaaacagc gagaaacttt atgcgctatc gctggatgat cacttattta
    19321 ttcggtgctt caccaatgag tgagaagaac tactttttag atgaatcaca tccgcaagaa
    19381 cctgttcgca gtattcgcaa cagtgcgctg ggctatacga atcatccaaa tgtgaaagtt
    19441 tcctatgctt ctatgaaaca gtatttagca gatatcgagc gaatgatcga agaagggaaa
    19501 ctttcggagg agaaagaatt ttatacaccg cttcgtttcc gaggcggaaa gaaagtcgca
    19561 gatttagcaa caacaggtgt tcgttatatt gaattgcgga atatcgattt gaatccttat
    19621 gcaagattgg gtatcaatcc agagcaagtt cggttcttac aattattcct gatgtacatg
    19681 ttatggacag aagaaaaaga agactgtgac caatgggtag cagaaggtac gactcgaaat
    19741 aacaaagtag cactagaaca accatcagat caaacagaat ttcatcaaga aggtagagaa
    19801 attcttgaag gaatgaagca aatgctggtt gaattggatt ggttggattc tctttattta
    19861 gtagaggaag cattgactca aatggatcat cctgaacaaa cgttagcagc gaaactctat
    19921 caagaagcac agctatcgag tcagcaagaa gttgctgtgg cattgggaca tcaatattat
    19981 aaagaaagcc atgaacgtcc ctatcagttg gccggttttc gcgaaatgga actttctact
    20041 cagatattta tgttcgatgc catccaaaaa ggtgtccaag tcaaagtatt agatgagtcg
    20101 gatcaatttt tgcgtctgca attccaagac catgtagaat atgtgaaaaa tgcaaacatg
    20161 acaagtaagg acagctatat cgtcccactt atcatggaaa acaaaacagt aacgaaaaaa
    20221 gtcttaaaag aagctgggtt ccgggtacca ggaggcgcag aattttcatc catggaagaa
    20281 gcggtaaaag cttatccgag atttgccgag caggcatttg tgatcaaacc taaatcaacc
    20341 aattacgggt taggtatcac gattttcaag gaaggagcta gtctggaaga ttatcaagca
    20401 ggtttagcca ttgcttttcg tgaagacagt tcggttttag tagaagaatt tatgccggga
    20461 acggaatatc gtttctttgt gatcgacgga gaagtccaag ccatcatgtt gcgagtccct
    20521 gctaatgtta ttggtgacag tatccgaaca gtgaaagaac ttgttgaaga aaaaaatagt
    20581 gaccctttgc gtggaacgaa tcatcgtgca cctttagaat tgatccaatt aggtgaatta
    20641 gaacaattga tgttgaaaga acaagggttg acgatcgaat cagttcccca agccaatcaa
    20701 attgtttatc taagggagaa ctcaaatatc agtacaggtg gtgattcgat cgatatgact
    20761 gatgaatttt ctgaagctta caaaaaaatc gccgtttctg cggtagaagc actaggagct
    20821 aagattagtg gtatcgattt gattatacca gataaagaaa tcgatcctac aactgataaa
    20881 aaagcatatg ggatcatcga agcaaatttc aatccagcca tgcatatgca tgtttatcct
    20941 tttgcaggaa aaggcagaag attgacgatg aatgtattga aattgttata tcctgaagta
    21001 ttttaaaaga aaaagctttt gacagattgt cctatttgat gtcaatctga tcaaaagctt
    21061 tttttgcatg taaaaattta tgtgtttttt cgttttaaaa taaacgatcc cagaagcttt
    21121 ttttcttttt tggtttttct ttttcagctg gcgaagagtt ttcttctggg tatttttttt
    21181 cgatatcaat cacaggttca tttactgctt cttttgctgt taagagcaat ccgaattcct
    21241 caggatttgc agtgacgtaa tcgttgacta cagtgaaacg gctattgttt ttcgttgcta
    21301 gctggatata ttggttttgg acagaaaggg gtagagcccc attcaagagt atggaagcat
    21361 ctggatgttt tttgagttct tttaaaaagt tttctttgtt ttttggttgg atcatttcag
    21421 caacagtcat actaagatag cagcgttccc tgaatgtccc taaatattta tgctgttctt
    21481 cagggttcac taaaggtgta ccataaagtc ccttatccaa atggcttttt acatcatctt
    21541 gtgccataaa aaataccctc cttcttctct ttgtctttct tacgattata gcatattccc
    21601 aataatacct aaaacatatg aaaaagcggt tgcttttgtt caacgattca cttaaaataa
    21661 gaatgaaaat cattctcaat tagaaaggtg gattggatgc gctacggacg actagtagca
    21721 ttattagtta ttttaagtag tatttcattg ttcatcggag tatcgaatgt acaattgtca
    21781 gaactgctcc agttagatgg gcaaagctta caaatcttgc tagtgactcg tttgccacga
    21841 acgatttgtt tgatccttgt gggagcgacc agtagtattt gtgggttgat catgcaacat
    21901 ttgacccaaa ataaatttgt ttcaccaacg actgcgggca cgatggatag tgcgcgttta
    21961 ggtattttag tggctatgat tttcctacct ggtgcatcct tgattgtccg atccttgaca
    22021 gcattttgct ttgcttttgc aggaacattg ctttttttat cccttacgcg attgttcctc
    22081 cagaaaaatc aattgatgct tccgttgatt ggagtcatgt tagggaatat cattggttca
    22141 gttgctactt tttttgctta tcaattccag ttggtacaaa atatgacttc atggcttcaa
    22201 gggaattttg cgactgtgat acgaggaaat tatgagttat tgtatgctgt tgttccattg
    22261 ttgctcttgg tttggctatt tgcttaccga tttacgatca ttggtctggg cgaatcgttt
    22321 gcagtaaatc tgggaataga ttaccagaag atgcagtttt taggcattgg cttagtatca
    22381 ttggctagtg cagtcatgtt gatcatggta ggaagcattc cttttatcgg agtgatcatt
    22441 ccgaatcttg tctctagaat atatggagat caagtgcaca aaacaattgg cgtaactgct
    22501 ttagcaggta gtttgttctt agtattttgc gatcttgtcg ctcgcgtgtt gatttttcct
    22561 tatgaaatac cagtcagtgt gatcgttgga atcatcggtg gggctatctt cctttatctt
    22621 ctgataaggg gacgacgata tgcttaaaaa aaagccatct atttttattg gtatgcttgt
    22681 tcttgtttta tttgttacag gaatgtactt gacgatccat acatatggaa actggcattt
    22741 tgcatgtgca ttgaggagta agaaaatttt tgcatttatc cttgtctcgc tagctgtcag
    22801 cagtgccaca atcagctttc agacaattac gcataaccag tttttgactc cttcagtatt
    22861 gggacttgag tcgttatatg tccttgtcca aacggtcctt ttcttcttta tcggaggagt
    22921 gacgatgctt cagcagacag gtacagtttt tttcttattg aacgttgggc tgatggtcgg
    22981 gctgagtcta ttgttatttt tctttctttt gaaaaaaatg agagcgaatc tttttttatt
    23041 actgatgtca gggatgattt taggtacgct ttttggtagt gtcagtacct ttttacaagt
    23101 catcatggat ccgaatgaat atgatttgct tcaaggcaga ttatttgcaa gctttggcaa
    23161 tatccagagt cagtatcttt tgcctgcttc tttgatcatt atcggctgct ggtacctgtt
    23221 atttcgatat cgacatgtgc tagacgtttt ccatctcgga aatgaacaag cagtaaacct
    23281 cgggatagac acagatcgtt ttgaattttt gattttatgt tgtgtcagtc ttttgacagg
    23341 gacatcaacg gctcttgtgg gtccagttac ttttttaggg tttattgtcg caaatatcag
    23401 ttatcgtgtc ttttctactt atcgtcatgg tcagctattt atcggaagct ttctggtagc
    23461 tatgctgttt ctgacaggag gacagctcgc agtagagcag attttcggct ggaatacaac
    23521 agtgagtgtc gtcgttgaat ttgtcggagg aatttatttt gtcacaaaat tgattcgcga
    23581 aaggaagagt atcctatgat tgatttacaa aaggtcaata aactgtacca tggaaaatca
    23641 gtggttaaag atgtacagtt aacgattcct gaaaagaagt tgactgcttt tatcggtcca
    23701 aatggtgctg gaaagtcaac ggtgttgtcg atgatcagtc gtttgatacc aaaagataca
    23761 ggtgaaatct atttagacca taacgaagta aaggcttgga aatccaatga attagccaaa
    23821 aaattatcga tcctacgaca atcgaatgaa ataaatgtcc aaatcaccgt gaaagaatta
    23881 gtagaatttg gacgatttcc ttatacgaaa ggaaaattga cgacaaaaga cgaggaaatc
    23941 gttcaggaat cactggaaca ccttgggtta gaagaaatag cggatcaatc gattgacact
    24001 ctttcaggcg gtcaactcca acgtgcgtat attgcaatgg tgctagcgca agacacggat
    24061 tatattttac tggatgaacc tttgaacaat ctagatatga attttgcggt tcaaatcatg
    24121 cagattttaa aaaatttagt acaagaaatc gggaaaacaa ttgttattgt tcttcatgat
    24181 atcaactttg ctgcaagtta tgcagacgaa attgttgcaa tgaaagatgg acagttattt
    24241 acgcaaggaa cgacccaaga aatgataaaa aaagatgtat tggatgaatt atacgaaatg
    24301 gacatacgga tttgtgagat tgaaggccgc agattctgtc tttatttcta aaactaacat
    24361 taggagagaa gagatgaaaa aattagtagt aggtatcttg attctagcat catttggttt
    24421 agcagcatgt ggaaatagca acaacaccag tcaggcagac acaaaaaaaa gcagcacaca
    24481 aactgaaact acattgacga taacagatag taatggagac caaatcgagg tgccaaataa
    24541 tccagaaaaa gtcgtcgtat tcgacaatgg ttctttagat acgatggatg ctcttggtgt
    24601 tggagataag gtagttggag cagctacaag cagccttcct gagtatcttt catcctataa
    24661 aaaagtagaa tcagcaggtg gaataaaaga accagactta gaaaaaatta atcagcttca
    24721 gccagatcta atcatcattt ctggccgaca aagagatttt caaaaagatc taagtcaaat
    24781 tgctccgacc attttccttt ctttagatgc gaaaaatcca tgggaatctt tccagcaaaa
    24841 tgtcactgct ttaggggaga tctttggtaa gcaagaagaa gctaaaactc aattagagga
    24901 attatctagt gcaatcgatc agacgaaaaa gaaagcagaa gctactgaca aaaaagcact
    24961 agtcacactt gtgaatgaag ggcaattatc agcctacgga tctggttcta gattcggttt
    25021 catccatgat ttatttggct ttgaacaagc agatgatcaa atcgaagcat ccactcacgg
    25081 tcaaagtgtt tcttatgaat atgtgctgga aaaaaatccg gatatcttat ttgtagtaga
    25141 cagaacaaaa gctattggtg gagacgacag caaagatgat atttctgcca atgaactggt
    25201 agcacaaacg aatgctggta aaaatcagca gatcatctcc cttgaaccag atgtctggta
    25261 tttaagcggg ggcggtttag aatcaatgaa actgatgatc gaagatgtga atcaagcatt
    25321 taaatagcat aaataacaga ggattaaact ctcatactat gtaacaataa tgtttcttac
    25381 attcttaaat agcaagagcc tatcctcaaa gaagttatca aaaaccatcc gtaaaatcgt
    25441 attgatgatt ttacggatgg tttttattta tttgagaaat cttttttcaa cgtgaattca
    25501 ttatctacat catacgggtt gattctagaa tggggagtgg caaaaaatag tgtgatccat
    25561 tttttcagca tcaagatcgc ctcctttgat ttgaatcaaa ggtacaaagc gaaacttaga
    25621 taaaacttaa atttagatat ttttattttg taccgatctc ttctttaaac gatgttccat
    25681 ctgctgcttc tcggcaataa gtccactaga ctagaaaata tgagaagcta ttttctgtcc
    25741 agcgttctta ttactcaaaa caaatcgcag ttgtcacaat ctcttctaaa cgatgttcca
    25801 tctgctgctt ctcggcaata agcccactag actagaaaat atgagaagct attttctgtc
    25861 cagcgttctt attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acaatgttca
    25921 atcagctgac cttcggtatt agctcaaagc actgatttca caacctctat ttaggcatgt
    25981 gtctcagcaa gcggttgata gttgatgatc tgcatttttc gataaaaatc ggcgggaagc
    26041 ttactccacc gttttagtaa ttgatagaaa taactctctt ctgctttgat tttatactcg
    26101 cttaatatca atccaaaact attcgttttt tttgaagcta attttttata aatatccaat
    26161 gctttggttt tatcttcatt gacaaagagt gtttttactt caatataaga accctcgata
    26221 ttttgtgttt cttcgataaa atagatgttt tttatatatt ccttcatagt gattcctcca
    26281 aagaagtctt ttatttgata agtttactct accgaagagt tgttaataat ccgtgaacaa
    26341 aaagtaattc tttttccaat agttgttaaa ggttttttat tttttatagt attttttgtt
    26401 atttaagaaa ggaataaggt taaacaaata acaggttgct ttttgggtct ttttccgttc
    26461 aagaaactga acgaagaaaa gggaaagttg tctcttttgt gataagagaa atcataataa
    26521 acgaatgact tactttccaa taaattgaga acagtcagaa ccagacaaat tagttgcatc
    26581 tgatgaataa agtgattatt ctatgacatg aggtgataca gatgaaatta gaagtgacaa
    26641 aagaagcaca agaagtattg aagaataaat tagaagcaga cgatcaactt ttattagata
    26701 tcgaaaacgg tgacggtcca tttgcagaaa gccaagtcag ttgccaattg gatacggcat
    26761 ttcgattgat cattgtcaaa aaagatacac aaacagatct aagtctttat tctgtagtgg
    26821 ctgatacacc agttggacca atcaaaatca aagacagtgc aatactttac atggatgatc
    26881 catccacact tgctttagaa ccaacttata atagtttaca attaaaagga ccaagcggct
    26941 tgagaaaagg caacttgcaa gttgttcgaa aagactagag ggataaaatg ggaaaattgg
    27001 cgatcatcag cgacctacat gtggacatca ataaattcgg cgaatcagag ctgatgcagc
    27061 tttggcaagt tttgcaaaag cacaagatca ctcggcttca tctagccgga gatacggcta
    27121 ataaagtaga ccgttgccta gctgttgtcg aatttttcgt caataaagga ttatctacga
    27181 catttcattt cggcaatcac gagttggcag atgtgcccaa tgaacagatg atggaccatt
    27241 ttccagaccc acatttttta aatgaacggt atattgcttt aaatgagcag accgttcttt
    27301 tagggatgaa tggctggtac gactatcagt tttccgaatt gaaagattac gaggcaatcg
    27361 tacgaatgaa gcgtttgtat tggtatgatc ggttcatcca gcgtgggaaa acagatctcg
    27421 aggtcaatgc agaaatgctt gcagctgcaa aaaatttgct agaccagctg gaagcaaaaa
    27481 aacttgaggt gattttatcc actcatttcg ttcctaaacg ggcatttatc atgtatcaat
    27541 ctgctcctta tgagcgttgg aacaaattaa atgcattttt aggatcagaa tcattcggag
    27601 aattacttga ccgttattca aatatcaaac aagtagtttt tggccatacg catcgtcgct
    27661 ttgaagataa atccatcggt cacacgattt acagctgcag accttttggt tattattatg
    27721 aatggcagct gacccgagat tttgtcttga aagaacagtt gctagacagc tatgatccta
    27781 tgaaattacg tgtcctcttg cgtgcccatc acccagcttt tcaggcctat caaacacaac
    27841 atttgcaaga ggaatttgaa caagcgatga caatcgttcc gtattgagac agcattagta
    27901 atgtgtaaaa gaaaatacct tgtaaaacat aaggataagt aagagcagta gatccattta
    27961 tcgtggatat gctgcttttt ttgcggaaaa taatcagcga atgtttattt gatcggatga
    28021 tttgtaactc gcagagtact agatgcaagc gtgtattctt tttttgaacg ataatcacaa
    28081 aaaaaaatat aatatacatt ttttatttaa ttataattaa tattgattga agtctaggca
    28141 gtcaagtcac attttgatag ataggagggg gacttacgaa ttattttaaa ggctatgaca
    28201 gctgtatttc tagattgtgt ttgcatcaag ttgcaataaa aactagaaat caaatcgggc
    28261 tgataatcat ttataactaa tcgatacata ggaccaaata taggtctatg ttcttttatt
    28321 tcataagtat cgtaaaacag aattttgcta tggattaatc caatcgactg atatgtttag
    28381 taaataaaga aagaggaatg tcaatgatga aaaaagaaat cgtattaaca gcagcaatga
    28441 tgttattcag catggtagca agtacgactt ttgtttctgc aactgaagta tacccaaagg
    28501 aatataacac agaaggaacg attacatttg aagcaggaga tgagggtgta actcctcctg
    28561 ttgatccaga gaatcctgat cccaataaac ctgtcgatcc atcagatcct ccaagccctg
    28621 gaacaggagg ggcattatcg attgattatg gatcaaaatt caaatttggg actcaaaaaa
    28681 tttctactgc ggataaaacg tattatgcag ctgctgatgt gatgaacgat gggtctagaa
    28741 aaccgacata tgtccaagtg acagatagga gaagtacctt atctgggtgg aaattaagtg
    28801 tctctcaacc agaacagttt aaaactgcca gtggggatga actagttgga gcacagctga
    28861 aatttacgaa agggcaggct gtttctttgg ttgatccaac atatacgccg caaacggtga
    28921 attctgaatt aacgttgaca ccgggaggaa acaatacgtt agcaattaat gctaaatcag
    28981 gaacaggtgt ggggacttgg gtctatcgat ttggtgcaaa tgaaaatgaa aatcaagatg
    29041 cggtacagct ttcggtaccc ggtaaatctg tcaagttagc gcaacaatat tccactaaat
    29101 tagtttggac attagaagat acacctaaca actagtttac tgaaaagaac tgttaaaaat
    29161 aaatacgtag tcatattgtc ttgcgaggta atcgagcaaa aattgtcaaa ggctaggcta
    29221 aatttgtttg gatacgaata gttcatctag gaatttaacg atcaggagga aaagatatat
    29281 tgaaaaagag gaggatcgtg ctcattttaa gcagtctctt agtgactaat atctttccga
    29341 tcatagggta ctctttggaa ttgaatcagt tggagcatgg aaatagaaga gacgaagaaa
    29401 gcaaactcac ttcgacattc gacagtttaa tagaatccaa ccagacacaa gaaagcagtg
    29461 aggatttaag tatttcgagt agtggagaga ccactgacaa cgtagaagct gagggttcgg
    29521 acaaacaagg actagaagat gcaccaattt ctgcggttga gctgcctgac gatcccaata
    29581 ttatttctat cgataaaatt tttcaaacac ctatcggtac tagcacgtcc atattggaaa
    29641 atgggaagtt actgcagttg aacccagcag aaaggtctca aagaggagct atttggtcaa
    29701 ataagaagat tagtttactc tcggatttta catttaaatc ttatttatac ttaggaaatc
    29761 aacgagatag agcgggagat ggcatgacct ttacattgac tggcgatcct agaatggcta
    29821 gtaatcccag tcaagttatt ggatcgccag gtatgggaat tggctcatat tctactcgtt
    29881 ctggccaacc ttacattgcg aatgcgctct cgattgagtt tgatacgtat aaaaatagtg
    29941 gttcttctga tcgaatggat cgagagataa ctgctgataa tagagggcat ggacatgtcg
    30001 cttttgtcac gcctaaacca aataataata attattctgg agagcatact ggcgtgacgg
    30061 tagctcctac atttctttct aatggcacat ggcgcttgtt aataattaaa tgggacgcgg
    30121 agcaaagaag tcttacttat gatttggaag gtgtcggtcg ctcttctcgg attatacctg
    30181 atctcattag gcagtttggt tctacagaag taaattgggg gtttacttct tcaacaggta
    30241 ctttttttca agaaaatgct gtcgctgtca cgcgacttcc atcgaatgtc acatcaacag
    30301 ctgatgtaaa agtcaacgat agtgattatg gggccatcgc tgaagctgga ggaaacgata
    30361 agataactat cagaaataca ttgaaggtcg agggggattt tcttgaatat aagaaaatgc
    30421 agactagtat cgacctccca caagaattaa ctattcccga gcatatcttg atcaatggaa
    30481 atcaaattga tgccaaagat atcttgataa ccggaaatcg agtcacgcta aatctgacag
    30541 attattttat tgctggagat acgttaataa tcgaattgga gacaactttg caggaagtaa
    30601 ttcctgaaaa agtactcact atgcattttg aataccttga aaacgggaat ttgattgagc
    30661 aatcgaatga aataaaccta aagatcgcaa agctgaagga gatagatatc catgtttatt
    30721 ataaagataa agacagtcag attgatattg ctgaaatgaa aacaatcact gggaaaatag
    30781 gagagaagta taaagaaact cctattgata ttgaagggta tgtttttgac tcggattcag
    30841 cgaatacaga aggcatcttc tccgaaaata cagaggatat ctatttttat tacagaaaag
    30901 gcaaacttta tctctcaact gctcctcaat atgtcaattt tggaaaacat aaaatatcca
    30961 gtagaccatt aagtgaattc ggacagtttt caggtgggtt gaaaattata gatgaacggg
    31021 cttttggaag ttggaaatta caattgaaac aagagaaagt tcttacaaat ggagattttg
    31081 agcttccaga agctctttcc tttgttacct ctgaaaatac aacggttata gggacatccg
    31141 ctgttacgat tttcgaaagt gatcaaaagg gtgaaagcga tttgtcctct cttttagatt
    31201 ctacagctca tcgtggaatc agaataaata ttcctgtaga aaaccaaaga atcggaacct
    31261 ttgaggggaa actatcttgg atacttgcag atgtcccagg aaattaacag gaagagaaga
    31321 atataacaaa attattgagt ttcaagaagg gcacaggtac cataggctct tgtgtcccac
    31381 agagacaaga ttttgttata gtcttctctt acatatgatt aaaggagcga ttttcttgag
    31441 accaaaacaa caattattta taacactcct agttatttta ggggcacttt ttaacaatat
    31501 atcagtgtca gctagtgcat ttaatttttc agtgacgccg ataacttcag agaatcaaat
    31561 cgacaagaga aaaacttact tcgatcttca acttgatccg gatcaggaag tagaagtaaa
    31621 agcggaattg agaaatgata cagaaaaaga agtgaaaatc gatatttctg tgaatagcgc
    31681 aaccaccaat tcaaatgtga tggttgaata cggaaaaaac gagattgaaa aagacatgag
    31741 cctgatcttt gatctggtag attatgtgag ctatccacag atagtgacgc taaaacctaa
    31801 aagtgtccaa accgttgctt ttcatgtcag gatgccgaat gagcgatttg atggtgtatt
    31861 ggctggtggg atcacattcc aagaaatcca gacggaaaag gaccaaacag aaactaagga
    31921 tcaaagctta tcgattgaga atgaatacac ctatattatt gctttgttga tgcaacagac
    31981 actgaacgaa gttgctccga accttactct tcatgaagtt aaaccagatc aaatcaatgc
    32041 aagaaatgtc atcttagcaa acgttcaaaa tgatcaaaaa acctatatca atcaagtagt
    32101 tattgaaaca aaaattacaa aaaaaggaca ttctgaagtt ttatatcaag aggaaaaaga
    32161 aggattgcag attgcgccga atacaaattt ttcttttcca actgctttaa atggtcaacc
    32221 gctaacccca ggtgaatatc accttacaat gactgtttta ggaaatgaaa atgaaaatgg
    32281 aaaattttcg agaaaaaaag gaaatactac gatcaactat accaatcaat gggtatttga
    32341 aaaagatttt acaatagacg gaaaagtagc caaggaattg aacacgacgg atgttacgat
    32401 taaaaaagac aataattgga tttatatctt agtagcttca cttttcttat tgtttatttt
    32461 attatgcata cttttgtttg ttttgagaaa aaaagaagag aaagaaaagt aaggttaaga
    32521 taacaaatag taaattttta ttattgtagg atggttgggc tctttttata
//
LOCUS       DAMEEU010000026        32533 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.027, whole genome shotgun sequence.
ACCESSION   DAMEEU010000026 DAMEEU010000000
VERSION     DAMEEU010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32533)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32533)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32533
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.027"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            131..505
                     /locus_tag="PB779_001219"
     CDS             131..505
                     /locus_tag="PB779_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDE0738755.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="PB779_001220"
     CDS             complement(619..1248)
                     /locus_tag="PB779_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDE0738756.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="PB779_001221"
     tRNA            complement(1382..1454)
                     /locus_tag="PB779_001221"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="PB779_001222"
     tRNA            1668..1741
                     /locus_tag="PB779_001222"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="PB779_001223"
     CDS             complement(1879..2043)
                     /locus_tag="PB779_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738757.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="PB779_001224"
     CDS             2338..3666
                     /locus_tag="PB779_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HDE0738758.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="PB779_001225"
     CDS             3868..4701
                     /locus_tag="PB779_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HDE0738759.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="PB779_001226"
     CDS             4717..5454
                     /locus_tag="PB779_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HDE0738760.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="PB779_001227"
     CDS             complement(5609..6577)
                     /locus_tag="PB779_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HDE0738761.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="PB779_001228"
     CDS             6809..7642
                     /locus_tag="PB779_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HDE0738762.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="PB779_001229"
     CDS             7676..8515
                     /locus_tag="PB779_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0738763.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="PB779_001230"
     CDS             8541..9101
                     /locus_tag="PB779_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDE0738764.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="PB779_001231"
     CDS             9300..11021
                     /locus_tag="PB779_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HDE0738765.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="PB779_001232"
     CDS             11186..12328
                     /locus_tag="PB779_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HDE0738766.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="PB779_001233"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="PB779_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HDE0738767.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="PB779_001234"
     CDS             14128..14775
                     /locus_tag="PB779_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HDE0738768.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="PB779_001235"
     CDS             15168..17813
                     /locus_tag="PB779_001235"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HDE0738769.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="PB779_001236"
     CDS             18123..19436
                     /locus_tag="PB779_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HDE0738770.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="PB779_001237"
     CDS             19426..20079
                     /locus_tag="PB779_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDE0738771.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20826
                     /gene="radC"
                     /locus_tag="PB779_001238"
     CDS             20134..20826
                     /gene="radC"
                     /locus_tag="PB779_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HDE0738772.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGNVIPSQQDMNFTKRIQKCGEMMGITVLDHLIIGRKRY
                     FSLREEGMMEEK"
     gene            20976..21176
                     /locus_tag="PB779_001239"
     CDS             20976..21176
                     /locus_tag="PB779_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDE0738773.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
     gene            complement(21430..23109)
                     /locus_tag="PB779_001240"
     CDS             complement(21430..23109)
                     /locus_tag="PB779_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDE0738774.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
     gene            complement(23111..23323)
                     /locus_tag="PB779_001241"
     CDS             complement(23111..23323)
                     /locus_tag="PB779_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HDE0738775.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            23716..25446
                     /gene="efrA"
                     /locus_tag="PB779_001242"
     CDS             23716..25446
                     /gene="efrA"
                     /locus_tag="PB779_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HDE0738776.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            25443..27203
                     /gene="efrB"
                     /locus_tag="PB779_001243"
     CDS             25443..27203
                     /gene="efrB"
                     /locus_tag="PB779_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HDE0738777.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            27298..27495
                     /locus_tag="PB779_001244"
     CDS             27298..27495
                     /locus_tag="PB779_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738778.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            27648..28133
                     /locus_tag="PB779_001245"
     CDS             27648..28133
                     /locus_tag="PB779_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HDE0738779.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="PB779_001246"
     CDS             complement(28237..28830)
                     /gene="clpP"
                     /locus_tag="PB779_001246"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HDE0738780.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            29010..29537
                     /locus_tag="PB779_001247"
     CDS             29010..29537
                     /locus_tag="PB779_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738781.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            29628..30365
                     /locus_tag="PB779_001248"
     CDS             29628..30365
                     /locus_tag="PB779_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDE0738782.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            30369..31286
                     /gene="miaA"
                     /locus_tag="PB779_001249"
     CDS             30369..31286
                     /gene="miaA"
                     /locus_tag="PB779_001249"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HDE0738783.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            31288..32517
                     /gene="hflX"
                     /locus_tag="PB779_001250"
     CDS             31288..32517
                     /gene="hflX"
                     /locus_tag="PB779_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HDE0738784.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
BASE COUNT        10772 a         5522 c         6874 g         9365 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaatcattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tctggtaatg ttattccatc gcagcaggat
    20701 atgaatttta ccaaaaggat acaaaagtgt ggagaaatga tggggatcac tgtactggac
    20761 cacttgatca tcggacgcaa acgatatttt agtttgagag aagaaggaat gatggaagag
    20821 aagtaagttg ctttcttgca aaaaaaatga agcaagtgta caattatatt gtaattttgt
    20881 ttgggaatag aagttgaaac atctgttgca cctctatcgt acacgagcaa tgttacaatt
    20941 taaattagtg cttttggcac gaggaggata ttattatgga aaacggaaca gtaaaatggt
    21001 tcaacgctga aaaaggattt ggatttatct cacgtgaaga tggaagcgac gtattcgttc
    21061 acttctcagc tatccaaggt gacggattca aaacattaga agaaggtcaa gcagtgactt
    21121 tcgacgttga agaatcagac cgcggcccac aagctgcaaa cgttgtaaaa gcttaatttt
    21181 atctgtaaat caaattgatg gtagacatca atttttacga gagaacaaag cgagtaacaa
    21241 aaatacctgc cacaagagac aatttctctt gtggcaggta tttttttgta tgaaaaagta
    21301 aataaattta agaggctatg aaagagccac cttgtatcaa ggaataagaa caaacaaaaa
    21361 tggcttctca tgtttttcat ttgttttctc ttatattcag gacaaggtgc tgatttcata
    21421 acctcttatt tattcttcat ctggtgtcat taccattggc aaaatcattg gatgtctttc
    21481 tgtacgttcg aataagaaag gctgaagcgc gccagtcatc gcttctttca atttatattc
    21541 tgaacagtca ggtccattca aacattctct taaagcgtgg aataagattc gctgagcttc
    21601 attgatcatt tctcctgatt ctcgcatgta gacaaatcca cgagagagaa tatctggacc
    21661 agccaagatt tcttttttct tgatatccac tgtcgcgaca gctaatacaa gaccttcttc
    21721 tgaaagcagg tgacggtcac gtaaaacgac attaccaata tcaccgatcc cgctaccatc
    21781 gatatacaca tctccagcca caaaatgccc agcaggacgc gcagaatcgc tagttaacgc
    21841 taaaacatcg ccattttcca tgatgaagca gttttctgca ggaacaccta catcttgtgc
    21901 tagagaagca tgtactttca acatgcggaa ttctccgtgg acaggaataa aatattttgg
    21961 cttcatcaaa cgaagcatta atttttgttc ttcttgtcca ccgtgaccgg aagtatggat
    22021 gttattgatt tttccgtgaa tcacttctgc accagcttca gacagcaaat tgatcaaatg
    22081 attgacactt gttgtattac caggaatagg tgaacttgaa aagatcactg tatcgtctgg
    22141 ctggatttgg atttgacggt gagtaccatt cgcgatgcgg ctcaacgcgg ccatcgcttc
    22201 tccttgagaa cctgtacata ggatcatcgt ttcattggca ggcaagcgat tgatttcgtg
    22261 tgcatctaca aatgtgccgt ctggaacttt gatatatcct aaacgttgac cgttgacgat
    22321 ggcattttcc atgcttcgtc cgaaaacagc gattttacga ccagttgcca cagcggcatc
    22381 tgctgcttgc tgcaaacgga agatgttaga agcaaagctg gcaaaaatga tacgtccttc
    22441 gatttttgaa aagatcttca aaatagaatg cccaatcgtt ttttctgatt tagtaaatgt
    22501 tggaatctca gcatttgtac tatcagataa aaggcacaag actccttctt ccccgatacg
    22561 agccatttta tgcaagtttg ctggttcgcc aacaggagtg aaatcgaatt tgaagtctcc
    22621 agtcgctacg atatttccag aaggtgtttt caccacgatc cctaatgcat ctgggatact
    22681 atgggtcgtt ctgaaaaagc tgacagaagt ctttctaaaa cggatgatcg tatcttcatt
    22741 gatctcatgg agctctgcat ctcgaagcaa gccatgctca tctaatttgt ttgtgatcaa
    22801 cgctaatgcg agaggaccag catagatagg aatatttgct tgtttcagca agtagggtat
    22861 tccgccgatg tggtcttcgt gcccgtgagt aatcaccaag gcttttactt tgtgtaagtt
    22921 ttgtatgatg tagctgtagt cgggaatgac atagtcaatt ccaagtaaat cgtcttccgg
    22981 gaatttgatc ccggcatcaa tcaaaatgat ttcatcttgg aattgtaccc catacgtatt
    23041 tttcccgatt tcacctaatc caccaatagc aaagacgcct gtctcgttat ttttgatgga
    23101 aagtttcata ttaaaactcc actaatgaga aatcagcatt ttctttttcg tactctagat
    23161 gacttccttc tagaagttga acgaattcaa tattgtatgg ggtattttct tccacacgtt
    23221 ggcgagcgtc tacatcgctt tttgcctcaa tgtaaagaga ttttgtttct tcccgtttag
    23281 ggttgcgtac ttttgtttct tgataataaa ctttatagat cattgttttg tctcctttat
    23341 ctgcgtaaag cagtgattta gctagttgat ttttttagac aacacaaaac gaggggacaa
    23401 gccacctggt ttttcatatg ctttgactag aatactggat tcgagtcaaa gagacaagcc
    23461 tcgtttttgc ttatctgttc ggatattttt tcaaccgtac cttctgtata aaaaatatac
    23521 aacaattaat tgttattcta gcataaaaca gcaaataagt atagaaatca actagattga
    23581 aagaaaaaat caatgtttat catcccgcta taatcataat gactttttta tgagagaagt
    23641 gttctattaa taggctcgtt gtgctatcat ttttagtaat gaaaatgtaa caaaagatta
    23701 aaaggagatg agaaagtgaa actaatgtgg cattatacca tgcgttataa gaaattcttg
    23761 tttttcaatt tcatatgcgt atttggtttt attttgattg aattaggact tcctacgatt
    23821 ttagcacgta tgatcgatgt aggaatccgc aatgatgatt ttgattatgt gaagcaacaa
    23881 gggatattta tgatcgttat tactgtaatc ggtattattt tgaatatctt gttaggttat
    23941 tttggttcga ggattacgac taatatcgta gcagatattc gagatgattt gttcgaaaag
    24001 atccaaagtt attcgcatca ggaatacgaa aatctaggcg tatcttcatt gatcactcgt
    24061 acaacaaacg atgcttatca gatcatgttg ttcctgcaaa atattttacg tatcggtttt
    24121 atggcaccaa tgatgttcat tgtcagtttg tacatggtca tgcgtacaag tgtgacactc
    24181 agtttgtatg tagtaggtgc attaccttta ctattattgg cagtcgtagc gattgctaag
    24241 gtgtctgaac cgttatctaa aaagcaacaa aaaaacttag ataaaatcaa cagtatcttg
    24301 cgggaaaatc tttcaggatt gcgtgtgatt cgtgcattcg tcaatgaaaa gtttgaagaa
    24361 aaacgttttg ctgtagtcaa tgagaattat gcttctagtt caaaaagctt attccgtttg
    24421 atggctgttg cacaaccggg tttttatttc ttatttaata tcgtaatggt attgatcatc
    24481 tggagcgggg cagtgcaaat cgatgcaggc gagcttcgtg taggagattt gattgcgttt
    24541 atcgagtata tattccatgc cttgttctca ttcatgttat ttgctagtgt gttcatgatg
    24601 tatccaagag cagctgtttc agctggacgt atccaagaag ccctagatgc caaaccttcg
    24661 attgtagaag atccaaatgg tatatctgat acaaaaacta aagggtatat cgaatttcaa
    24721 aatgtaacat ttgcttatcc aggccattcg caagagccag tgatacgaaa tgtcagtttt
    24781 acagcctctc caggagagac cgttgctttt attggaagta ccggtagcgg aaaatctacg
    24841 ttgatccaat tgatccctcg cttttatgat gtgagtgaag gaaagatctt gatcgatgga
    24901 gtagacgtga gagattatcg gctaagcaag ttgcgagata agattgggtt tattccgcaa
    24961 aaagcgctgc tatttactgg aacgattgca gataatttgc gatacgggaa agaagatgct
    25021 acgcaagaag aaatggaacg tgcagctgag attgctcaag cttcagaatt catttctcga
    25081 aaaccagatg gatttaatga acatttatca gaaggtggtt ccaatttttc aggtggacaa
    25141 aaacaacgat tggcaatagc cagagccatc atacgccgtc cggaaatcta tatttttgat
    25201 gacagctttt ctgcattaga ttatcaaacg gatgcgaagt tacgtgctcg tctgaaaaaa
    25261 gaaacgacag aatctactgt attgatcgta gcacaacgtg tgggaacgat catgcatgca
    25321 gataagatca tcgtattaaa tgaaggagaa gtcgtcggta tggggacgca tcgggagttg
    25381 ttggaaaaat gcccgattta ttatgatatt gccgcttctc aattatcaaa ggaggaatta
    25441 gcatgaaaaa aaccttttct tccttaaaac gtttagctcg atatatcaga ccgtatcgtg
    25501 agacttttct tttagtgatc ctatttacag ttctgacagt ggctttcaac gtggctttgc
    25561 catatgttac aggacttcct actacagaaa tcagccgtaa tattgccaat ggcgaatcaa
    25621 tcaatttttc ttatatattc aaatgtctca tttggatcac agttgttgga atagggtatt
    25681 gtatttcgca attactttct ggtgttttga tgacaaatgt cgttcaaagt gccatgcatg
    25741 atttgagaag agacatagaa gaaaaaatca atcgtcttcc ggtttcatat ttcgataaaa
    25801 accagcaagg aaatattttg tctcgtgtga cgaatgatgt agatgcagtc agcggtgctt
    25861 tacaacaagc ttttattggt atcgtaaatg cgatattggg aattacgttg gctgcagcaa
    25921 tgatgtttta tatccagccg atgatggcgc tgatctctat gatcatgatt ccaacatcga
    25981 tctggatctc aaaacgagtg atcaatgctt cgcagaaata ttttcaaagc atgcagaatt
    26041 ctcttggtga gctaaacggc tacgtccaag aaaatatgac aggttttagt gtattgaaag
    26101 tatatggacg cgaaaaagaa acattggaag gattcaaaaa agttaatcac agcttgaaat
    26161 actttgggtt tcgtgcagca ttcatttctg gcttgatgat gcctctagtt caattaactg
    26221 cctatgctac ttatattggt atggctgttc taggaagctt ttatgttatt actggggcga
    26281 tcgttgtcgg tcaactacaa gcattcatcc aatatatttg gcaaatcagt cagccaatgg
    26341 ggaacgtgac acaattgtct tcagttttgc aaagtgcatc agcggcaacg aaacgtgtat
    26401 tcgagatttt agatgagcca gaagaaaaag aaaacaaagt agatgcttca ctgccagaaa
    26461 cgattttagg agatgtgaca ttcgatcatg tcgattttgc atatgatccg aagaaaccat
    26521 taatccaaga tttgaatttt gaagtgaaag ctggtcaaac cgtagctgtg gtcggtccga
    26581 ccggtgccgg caagacgaca ttgatcaatc tattgatgcg tttttatgac gtagacaaag
    26641 gagcaataag gattgatgga atcgacacca aatcaatgag tcgcagtgat gtgcgttcgc
    26701 tatttggtat ggtcttgcaa gatgcatggc tttatcaagg aacgattgca gataatatcc
    26761 gcttcggaaa gcttgatgcg acagattatg aagtagttga tgctgcgaaa acagcaaacg
    26821 tagatcattt tatccgaacg atgccagatg gatatgatat ggccatcaat tctgagggag
    26881 acaatgtgtc tttaggacaa aaacagttgc tgacgattgc ccgagcagtg gtctccgatc
    26941 ctaaaatctt gattttagat gaagcaacaa gttcagtaga cacccgttta gaagcgttga
    27001 ttcaaaaagc aatggatcgc gtgatggagg gacggacaag tttcgtcatc gctcaccgtt
    27061 tatcgacaat ccgtgatgca gatctgattc tagtgatgga tcaaggtcag atcattgaaa
    27121 aaggaacgca tgagagttta ttggcacaag gtggatttta tgaaaaactg tataacagcc
    27181 aatttgctga ggaagcagaa taagtcatat aagaataaaa cagtttaaaa cttatttttt
    27241 gttctctatt cttgataatg gtaaagtaaa gttatcaaga aaagtgagga cacggagatg
    27301 gaacagtttt taaatgaaaa aattactgaa gccaaaagag aagttgatcg tttaacgcac
    27361 gtctgtcaga cgaagccttt tgattcagct gatttttttg aaaatgagtt tcaaatcgaa
    27421 cgcttggcag cacaaataga agtgtacgaa ttaattttaa aaaaagtaat agaagaaaat
    27481 atagatgtac aataaaaaca ggtaaaacgt cagttaccag atactgtaaa tagacatctg
    27541 gcctgagcag gttttacctg ttttttttct tatgaaataa atatatgcta tgataccttt
    27601 attcaatagg attagtttct acaaaaaatg aaaggagaaa aataaatatg gaacggttta
    27661 tagcatcaaa tgccacagtg attggtgatg tgacattgtc agaagatgtg acgatctggt
    27721 atcaagctgt tttacgcggg gacagtaatt ggataaaaat aggacaaaga acgaatatcc
    27781 aagatggtac aatcatccat gtcgatcatg atgcacctgt agatattgcg gagaatgtga
    27841 cggtaggaca tcagtgcatg ctacatggct gtacaatcga aaaaggggcg ctgatcggga
    27901 tggggaccac gatattgaat catgcggtta ttggtgagaa tagtttgatt ggtgctggat
    27961 cattagtaac agaaggaaaa gttattcctc ctaatgtctt ggcttttggt cgcccagcta
    28021 aagtgatccg tcctttgaca aaagaagaaa tacaaaaaaa caaagaaaac atccagcatt
    28081 atgtcgagat aggtcggatg catgcgcaag gaaaattcaa ggagcaaaga taggcagtag
    28141 catccataaa ataaaaaagg atggtcagtt tgagttgacc atcctttttt atttggttta
    28201 gataagagag cttaaaaaag cttcctttga aacagattaa tttaatgaag aactgttttc
    28261 catgacttca tcgatcaatc catatgcttt tgcttgttca gctgtcatat agttgtcacg
    28321 atctgtatct ttttcaatca cttcaagcgg ttgtccagtg cgttcagcta aaattttgtt
    28381 taagcgttcg cgtgtttgca aaatatggcg tgccgcaatt tcgatttcag ttgcttgccc
    28441 ttgagcgccg ccaagaggtt gatggatcat gatctcagca tttggtaaag caaatcgttt
    28501 accttttgta ccagctgtca gcaagaagct tcccattgaa gcagccatac ccataacaat
    28561 tgtttggaca tctgctttga caaagttcat tgtgtcgtaa atagccatac ctgctgtaac
    28621 tgaaccacca ggagaattga tataaagata gatatctttt tcagaatctt gagcgtctaa
    28681 gaaaagcaat tgggcgatga tcgaattagc aagatcatct gttacttggc cgcttaacat
    28741 gatgatacgg tctttcaata aacgtgagta gatatcgtaa gctctttcac ctcgtgaaga
    28801 ttgttcaatg actgtaggaa ttaaattcat aatagagttc ctccttgatt tcgtttagaa
    28861 atagtgtacc ataatttagt ttctaatacc taaaatgtag tatacatttt tggtcaaaaa
    28921 aggtcaaata aaaaacttag gcaaattagt cgcataaacc cgctttatgg tatgataagc
    28981 agagaaacaa aacaaggagg aacaacagat tgatagttgg tattactggc cttatcggag
    29041 tgctgacagg tgctgtagtt gtctatatcg gcatgatact gcaaatgcgt cacttggaaa
    29101 ataaagaaca gcgtagacgt gaattggaat tgaaagtcaa agaaatcgag acgctgaatc
    29161 aattaaataa aaagatcaac gagatcttgc aaaaacggac aacgctgatg gaagaatatg
    29221 tcagctttga tgcatttgat gattgttata tcacgattga cgattttgcg tatctccaat
    29281 cattttcagc gcaaaatagt ttttatctgc caaattatat tttagacgag ctatttaaga
    29341 atatctccca tcgaaaagtg attttatctc cagatgaaac aatgaagatt ggtggatatg
    29401 cttataaagg cggacgcgtg attttagaga attttacgga tagtctgact gaaatgatca
    29461 atgaaaaaaa agctcagttg aagactatga cgcgccagcc gattggtttc ttctcgaaag
    29521 atgatgtttg gagctgatat tttgaagcat tgccgttgca catgagagcg tggtaatgct
    29581 ttcttttttt cttaatgata caatagaact gaacggagtg aagaaagatg ttacaaatct
    29641 atgcccatcg cggaagcagc ggcacccacc cagaaaatac gcttcctgca tttgcagaag
    29701 ctgtacgagt aggtgcagat ggtatcgaac tagatgtcca tctaagcaaa gatggttatt
    29761 tgatcgttat gcacgacgaa gaagtggacc ggacgactaa cggtaaaggg ctgattcgag
    29821 aaaaaacatt ggaagaactc aaaaaattga atgcaggggg caaattcagc aaagaatttc
    29881 cagcagctaa agttcctgaa ttgagagaag tgttaggact gctcctccaa aaaaattacc
    29941 gagggatgct aatgattgaa attaaaactg atcagtatga atatcccggt atcgaagaaa
    30001 aattagccga aacattaaaa agtagagatt ggccttttca acatgcatat tgcagctttc
    30061 atttggattc tttggaaaaa atcgcattac tggaaccgga gatacagctg gacttattga
    30121 tgagtacttc tgataaaaag atccaactag cagcagaaac cccttatata gaaggagtac
    30181 atccaaaaaa tacttggttg ttcgaacatc cagtccaggc agctgatttt ccaaaagcaa
    30241 ttcgtgcatg gacgattaac gatgaagaag aaatggccaa atgtcaagaa ctcaaaatag
    30301 atggaataat aactgatttt ccggagaaag ctcttcggtg gaaacaatca acgaaaagta
    30361 ggtaaaatat ggaaaaagta ttagtgatcg tcggtccgac agcagtcggt aaaacagcgc
    30421 taagtgtgga actcgcacaa ctatttggag gagagatcat cagtggtgat tcattgcaaa
    30481 tctataaaaa tctggatatc ggtacagcaa aaatcaaaga agaagagatg aataatgttc
    30541 cgcatcattt gattgatgtg atcgaaccta ctcaacgtta ctcagccgct gattttcagc
    30601 attcaggtcg acaattgatt accgagattg cgaaccgagg gcacctacct atcatagctg
    30661 gtggtacggg tctctatatc caatcccttc tatatgatta tcagttagga gcgacagaag
    30721 aagcgaatcc tgagattaga aaaaagtatg aaacgttagc tgaaacaatt ggttcccaag
    30781 cattatggaa tcagttgaaa gaaaaagacc cggcagctgc tgagaaaatc cactggaaca
    30841 atcaacgcaa agtgataaga gctctggaag ttttagagac gacaggacat agtatcacgg
    30901 cacctaaaga agagccaaag caattgtatg attacctcat gattggatta gatacgaagc
    30961 gtagtattct ttatgaacga atcaatcaaa gagtcgattt gatgctagca gaaggtttag
    31021 tagcagaagc gcgtaaggtg tatgagcttg gagaagtcca ggccagtcaa ggtattggat
    31081 ataaagaatt tttcccttat tttgaaggga aagaaacatt ggaagaagca acagaacaag
    31141 tcaaactaca ttcgagaaga tacgcgaaac gtcagttgac gtggtttcgt aaccgtttgg
    31201 atgcacagtg gtttgatctt ataagtgagc caaatcaaaa aagtcagatt gagcaaacaa
    31261 tcaaaaaatg gctggaggcg gaataaaatg gaagaaaaag tgatcatcgt aggggtagaa
    31321 accgaagcaa accagcgtta cttttcagag tcaatggaag agctagttca gctgacgaat
    31381 accgcatcag gagaagtcgt attcacaatt acacaaaaga gaccacaagt ggatcggcaa
    31441 acgattatcg gtaaagggaa attacaagaa ttagttcaac aagcggatgc gcatgaagcg
    31501 gatttgatca tctttaatca tgagctaact ccgagacaga gccaactgat taccgatgct
    31561 gttggtcttc cggtaattga tcgcgtgcag cttatcttag atatttttgc gatgcgtgct
    31621 cgttcgaaag aagggaagct gcaggttgaa cttgctcagt tagaatacct gctgcctcgt
    31681 ttagtagggc aagggaaaac attatctcgt cttggcggtg ggatcggaac aagagggcca
    31741 ggtgaaacaa agttagaaac agaccgccga catatacgga ataaaatttt tgctgttaag
    31801 aaagaattga aagaagtaga agctcatcga gagcgcaatc gccaaaaaag aaaaaatagc
    31861 gagatttttc agattggact tattggctac acgaatgccg ggaagtcaac tatcttgaat
    31921 ctattgacac aagcggatac ttattcgaaa gatcaattgt ttgcaacgtt agatccattg
    31981 actaagagat ggcgttttgc tgaaggattt gagattactg taacggatac cgtcgggttc
    32041 atccaagacc tgcctacgca actgatcgat gctttccatt ctacattaga agaaagtcaa
    32101 aatatggatc ttttgctaca tgtagtcgat gctagttctc cagatcgtat tttacaggag
    32161 cagactgtct taaaattgat ggatgaactg aatatgaaag aaatgccgat actgactgtt
    32221 tacaataagg cagaccagat cgacccagcg atgttcacgc ctacgctatt cccaaatgta
    32281 ttgatttcta ctcagacgaa agaaggtaag atggcgttga tcgaagcaat caaacgtcag
    32341 ctgatggaac taatgacccc ttatacactt tctgtgccaa gcaacgaagg acagaaatta
    32401 agcgagttga gaagacaaac aatggttttg gacgaagcgt acatggaaga aacaaacgaa
    32461 tatgaagtta aagggtttgc aaaaaccaat tcaaaatggt taagaaaaaa ccaataaaat
    32521 tttatttttt taa
//
LOCUS       DAMEEU010000027        32453 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.028, whole genome shotgun sequence.
ACCESSION   DAMEEU010000027 DAMEEU010000000
VERSION     DAMEEU010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 32453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32453
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.028"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..506)
                     /locus_tag="PB779_001251"
     CDS             complement(<1..506)
                     /locus_tag="PB779_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0738785.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQVILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSM"
     gene            779..3250
                     /locus_tag="PB779_001252"
     CDS             779..3250
                     /locus_tag="PB779_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDE0738786.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(3353..5089)
                     /locus_tag="PB779_001253"
     CDS             complement(3353..5089)
                     /locus_tag="PB779_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HDE0738787.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSGFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(5086..5790)
                     /locus_tag="PB779_001254"
     CDS             complement(5086..5790)
                     /locus_tag="PB779_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0738788.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            5921..6424
                     /locus_tag="PB779_001255"
     CDS             5921..6424
                     /locus_tag="PB779_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HDE0738789.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            6384..6722
                     /locus_tag="PB779_001256"
     CDS             6384..6722
                     /locus_tag="PB779_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HDE0738790.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            6743..8161
                     /gene="ffh"
                     /locus_tag="PB779_001257"
     CDS             6743..8161
                     /gene="ffh"
                     /locus_tag="PB779_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HDE0738791.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            8273..8851
                     /locus_tag="PB779_001258"
     CDS             8273..8851
                     /locus_tag="PB779_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HDE0738792.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            8855..9376
                     /locus_tag="PB779_001259"
     CDS             8855..9376
                     /locus_tag="PB779_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDE0738793.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(9455..10009)
                     /locus_tag="PB779_001260"
     CDS             complement(9455..10009)
                     /locus_tag="PB779_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HDE0738794.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            10262..10537
                     /gene="rpsP"
                     /locus_tag="PB779_001261"
     CDS             10262..10537
                     /gene="rpsP"
                     /locus_tag="PB779_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HDE0738795.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            10549..10800
                     /locus_tag="PB779_001262"
     CDS             10549..10800
                     /locus_tag="PB779_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HDE0738796.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            10925..11716
                     /locus_tag="PB779_001263"
     CDS             10925..11716
                     /locus_tag="PB779_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738797.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            11886..12407
                     /gene="rimM"
                     /locus_tag="PB779_001264"
     CDS             11886..12407
                     /gene="rimM"
                     /locus_tag="PB779_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HDE0738798.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            12397..13158
                     /gene="trmD"
                     /locus_tag="PB779_001265"
     CDS             12397..13158
                     /gene="trmD"
                     /locus_tag="PB779_001265"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HDE0738799.1"
                     /translation="MKIDVLTLFPRMFEGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            13294..13641
                     /gene="rplS"
                     /locus_tag="PB779_001266"
     CDS             13294..13641
                     /gene="rplS"
                     /locus_tag="PB779_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HDE0738800.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            13899..14192
                     /locus_tag="PB779_001267"
     CDS             13899..14192
                     /locus_tag="PB779_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HDE0738801.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            15035..17362
                     /locus_tag="PB779_001268"
     CDS             15035..17362
                     /locus_tag="PB779_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDE0738802.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSATETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            17488..17817
                     /locus_tag="PB779_001269"
     CDS             17488..17817
                     /locus_tag="PB779_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HDE0738803.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     AEIKTSD"
     gene            17857..18861
                     /locus_tag="PB779_001270"
     CDS             17857..18861
                     /locus_tag="PB779_001270"
                     /inference="COORDINATES: protein motif:HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDE0738804.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKTKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            18858..20287
                     /locus_tag="PB779_001271"
                     /pseudo
     CDS             18858..20287
                     /locus_tag="PB779_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306286.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
     gene            20493..21665
                     /locus_tag="PB779_001272"
     CDS             20493..21665
                     /locus_tag="PB779_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDE0738805.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(21827..22282)
                     /locus_tag="PB779_001273"
     CDS             complement(21827..22282)
                     /locus_tag="PB779_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738806.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQQAAAEQASQQAQAAAP
                     EQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSKCYGN"
     gene            22872..23294
                     /locus_tag="PB779_001274"
     CDS             22872..23294
                     /locus_tag="PB779_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738807.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            complement(23460..24653)
                     /locus_tag="PB779_001275"
     CDS             complement(23460..24653)
                     /locus_tag="PB779_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0738808.1"
                     /translation="MTTYQRKLLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            24877..25254
                     /locus_tag="PB779_001276"
     CDS             24877..25254
                     /locus_tag="PB779_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDE0738809.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKKIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            25242..25580
                     /locus_tag="PB779_001277"
     CDS             25242..25580
                     /locus_tag="PB779_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0738810.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            25714..26157
                     /locus_tag="PB779_001278"
     CDS             25714..26157
                     /locus_tag="PB779_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HDE0738811.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            26419..27234
                     /locus_tag="PB779_001279"
     CDS             26419..27234
                     /locus_tag="PB779_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0738812.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            27244..27906
                     /locus_tag="PB779_001280"
     CDS             27244..27906
                     /locus_tag="PB779_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDE0738813.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGCIVMIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLF
                     AWIVSVIMIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVL
                     RIAFYYTLKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTM
                     DL"
     gene            28111..29775
                     /gene="alsS"
                     /locus_tag="PB779_001281"
     CDS             28111..29775
                     /gene="alsS"
                     /locus_tag="PB779_001281"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HDE0738814.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            29788..30498
                     /gene="budA"
                     /locus_tag="PB779_001282"
     CDS             29788..30498
                     /gene="budA"
                     /locus_tag="PB779_001282"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HDE0738815.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            30628..31125
                     /locus_tag="PB779_001283"
     CDS             30628..31125
                     /locus_tag="PB779_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HDE0738816.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
     gene            31310..31570
                     /locus_tag="PB779_001284"
     CDS             31310..31570
                     /locus_tag="PB779_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738817.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
     gene            complement(31932..32171)
                     /locus_tag="PB779_001285"
     CDS             complement(31932..32171)
                     /locus_tag="PB779_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738818.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
BASE COUNT        10921 a         5742 c         6496 g         9294 t
ORIGIN      
        1 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
       61 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      121 ttagcgatta gtttacgtga ttgattttcg tacagttcca tgagaatcac ctgcttcagt
      181 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtccttcca
      241 caatcatggc agagaaaacg ggtacgtttt aattctaaaa tagttaactt ttctttgact
      301 ttcaacatct gagtgcgtgt cgtataggaa ccgttgcgga taatacgaac cgatcgacag
      361 tgttcacaat aggaagaaga gtcatccaat tttcctttaa taaactgcgc ttgaacgcct
      421 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      481 agtaattttc tagtatgatt atccattgag agactccttt ggtaggatga cgttttggtc
      541 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      601 gaaaatcgcc ttcgattttc caccaacaca aaatattata gaaccctttt tttttgctat
      661 atgacaggaa tgaaaggtgt ttgcaagctt aatgtgagga acactttcca tatctgttct
      721 atactggata ggagaagttt ggaaatatcc agaaaacgaa atcaatcgag gtagccacat
      781 gaagaataaa tggataaatc gaagtaaaaa aaagaaagta acacaaagat catcagataa
      841 agtcatccgt ctttttccat cgtataaaga aggattaacg gcagatcaag tcaaggaacg
      901 aatagaaaaa ggtgcagcaa ataattcagt cgatcccaca ttcaaaacaa atcagcaaat
      961 cgtattggaa aacatattta cgtatttcaa tttgatcttt cttatcttag ccattttgct
     1021 ttgtttagta gaatcctata agaacttgac ttttttacca gttatcatag ccaatacagg
     1081 aatcgccatt tttcaggaaa ttcgatccaa aaagatcttg gacgaactaa atgttttaaa
     1141 tacagcaaaa gtcaatgtca tacgagacgg gatagaacaa acaatagata tagaagacct
     1201 tgtaatagat gacattgtta ttttagagac tggatatcaa attccagcag atgcagaggt
     1261 cgtggaaggg aaactgcaag ttaatgaggc tttattgaca ggcgaagcag atgaaataac
     1321 caaagaaata ggtgatccat taatgtccgg cagtttcatt gtttccggaa aagcttacgc
     1381 ccgattagac aaagttggag cagattcgta tatttcccag ctgacagtca aagccaagac
     1441 aatgggagaa ggagaacagt cggagatgat tgcttctctt aatcaattga tcaaatggat
     1501 tgggatcatc attattccta tcggtatcct gcttttttct caaagttact tttttaatgg
     1561 aaacacgatc aaagaaagtg tcgttgcaat ggaagcagca ttgatcggta tgatacctga
     1621 aggactgtac ttgctgacga cgattgcatt agcattaagt gcgactaaac tagcaaagca
     1681 aagagttctt ttacacaata tgaaaagcat tgagacattg gcaagggtaa atgtcctttg
     1741 tgtagataaa acaggaacga tcacagaaaa taaaatgtct gttcaaaaaa tgatcgtctc
     1801 taaaaaacaa gaaataatca gtcagtcaga tcaattggaa gcatgcattg ctgactatgc
     1861 aaaagcgatg gcaggagaca atgcaacaat ggaagctgtt aaagcatatt ttacaaaaac
     1921 cactgatcaa tcctatcacc atgttattcc tttttcttct gtccaaaaat tcagcagtgt
     1981 agcgttggca gacaaggtgt atgttttagg agcgcccgaa atggttttgc gcgatcaatt
     2041 gccggaatat gcggaagagt ttgtttcttt cgctgaaaaa ggctatcgcg tgttggtctt
     2101 tggtgtgtac gatgggattc ttgaagaacc agtattgaca gaagcagtca caccattagg
     2161 ctatattctg attgctaatc ctatcagaaa agaagcaaga gccacatttg attacttcaa
     2221 aaaacagcaa gtagccatca aagtgatttc tggagataat ccgctcaccg tatccaatgt
     2281 agctgtccaa gcagggattt cacatgctga tcagtacgtt gatgcatcta aattatcaga
     2341 agaagaatat gaagcagctg tcgaaaaata tacagttttt ggacgcgtca agccagaaca
     2401 aaagaaaatc ttcgttcaat tgataaagcg taacaataca gtagctatga caggtgatgg
     2461 cgtgaatgat attctagcca tgaaagaagc agactgcagt atagcgatgg cttccggaaa
     2521 tgaagccgcc atgcaggcct cacaagtggt cttacttgat tctgactttt cacgcatgcc
     2581 agaagttgtt gcagaaggac ggcgcgttgt gaacaatatt gagcgatcag ccagcttgtt
     2641 tttagtgaag aatattttct cctttttgct ctcactgttt tcagtgatct ttgctctgac
     2701 ctatccttta gaaccatcac aaatcacatt gattagtttg tttactatcg gacttccatc
     2761 tttcttgctt gctctagaag aaaacaaaaa gcgaatcaga gggaaattca tcatgaatgt
     2821 gatggaaaaa gctgtgccag gtggactaac agatatgatc gtagtcggtg cgttggtgat
     2881 ctgcggggtg actttgaatc taaataaaac agatgtttct acagcatcta ccatgctttt
     2941 gattgcagta gggttcctcg ttctctataa aatctgttca ccgctgaata aattcagaag
     3001 tcagatcatt cttttctgtg ctagcggtaa ctttttttcg gtcatctttt tgcataagct
     3061 gttttcaatc accggtatct cagctgtatc acttttgctg ttgagcattc tatttttctc
     3121 ggcagattcg atttttaggc atttgaccac attggtagaa tatttgtttg aacgtaaaaa
     3181 tgaaaaagag caaaagccgt ttagtcgcgt agctaaaaaa tttctatcga tatttaaacg
     3241 agaaaattga cgaaaagtat ctcaaaaaag agtaaaaaag aacaaccact cgtgtatctt
     3301 tcgaagcagg atgagtcatc caactttaaa acgcacgagc agttgctctt ttttacattt
     3361 tcggaatggt aacggtgaaa gtcgaacctg ttccaagatg actgtctaca gtaatcgtac
     3421 cattaaggag ttgcacgtag tcttttacaa tcgctaaccc taatccggtc ccgcctgaat
     3481 gtcggcttcg cgccttgtct acgcggtaaa aacgctcaaa gatccgttcc tgatcctcaa
     3541 tgtcgatacc tataccaaag tcttggacag aaaacgatag atcatctgtt gcctgatagc
     3601 ggataataat ctcgctgtcg ctttttgaat attggacagc attttcaatt agatttttga
     3661 taattggata aaggatatct gttttagtag taaatggttc gttctttcca atcaatcgaa
     3721 tcgtcaaccg tttcttttcg atgattggct gataattttg aacgatttgc tggaaataag
     3781 gttctgtata aattgtctgg atctcgtaag aattctcgcc atcttttgac agctggatga
     3841 tttcccgaat cagtttatct aaccggatcg catctttttg catgatctca agaaaagaag
     3901 tcagagtttg cgggtcatct tttgcaccat ccagtaaagt ctcggtaaaa ccaatcagtg
     3961 aagtcacagg agtttttaat tcgtgagaga cgttgccaac gaaatccttt tgtagctttt
     4021 ctaaacgtcg cactttcgtt aagtcatacg ccacccctag aatctgtccg gtaccttctg
     4081 aattagtaaa gtagcgcaaa ctcaagtcta atgtctgccg accttctgta agggtgatct
     4141 cctgatggat cagcggatgc tcaggagtca cttgatgaat cagctgaatg agttttggct
     4201 cttgaatgac ttctgtgtac cgctgttcag gttgatagct taccacgttt aaatgtagct
     4261 gcatctttgg attaagcagt agtaaacgag aatcagcatc atcaatcagg aatacgccaa
     4321 tcatcagttc gttcagtaac gtatataatt gctcttctgt ggtagtacac gcccgataca
     4381 tcttactcat ttgttcgctc aacgcattaa tcgtctgata caattcttcc cattgatcgg
     4441 gtgtttgcat gattacttcc gcctgattag gattttgcac catttttttt agtacgggca
     4501 gcacggtttt caatggctgg tttttttgat agatcagata atagatcatt cctgcaagaa
     4561 caaggaagaa agacagaaag aagaaaaaga cccaacggcg aaaactctca gttctcggta
     4621 aaaaaccgct tgtcggttct gcgatacgta aaatggcttc taactggcca ctttttttga
     4681 ctggtaatgc gacatataaa agatcctcat tcaaagtagt acttttgcgc aaagcgctac
     4741 ctaggttccc accattcaat acggctttga tttcgggacg ggagtttcgc tgttcattca
     4801 atgtttcatt gtttgtgtca aataagatct ttccagtagc atccattaaa gtaatccgtt
     4861 cgttcgactg atggacgaat tcttccaaag cagttttgtt ttgcgctgct tggaggtttt
     4921 cgacatctaa ttgccggatc agcagttgtg ctttttttgt caggtagctt tcttgctgtt
     4981 ccacgatctg ctgttgaaaa taatgggaaa tcaattgcca gccaccaaaa aacaaactaa
     5041 ctaaaagaat aagaaagaag agacgttcat aaattttttt ccatttcatc gtttgggttc
     5101 ctgaaactta tagccaaatc ctctaatagt caccaagtac tttgggtgtt ttggatctcg
     5161 ctcgattttt tctcgcaaat gactaacgtg tacatctacg attcggcttt gtcctgcgaa
     5221 gtcaaaattc caaatgcggt ctagcaatgt gtctcggtcg atcacacggt cttttcgttt
     5281 catgaaataa acaagtaatt caaattcttt cggtgttagt tcaatcagat ggtcgtctac
     5341 ggtcacttga taattggtca aatcagcagt gatttgtcca atcgatagat attcaggctc
     5401 agcttcatct tttgattgct tacgaggttc aattcgtctg aatattgctt tcatacgggc
     5461 taatacttcg cgaggactaa atggtttggt caaatagtcg tcagcaccta tttctaggcc
     5521 aatgatccga tccacttggt catctttagc cgtcagcatc aaaatcggtg tttcattttt
     5581 ttcttgacgc agccgctgag tgatctccat gccatccatc gttggaagca tcacatctaa
     5641 aatgatgaaa tcaaatgatt gttctaatgc taattctaat ccttcgcctc catctgtggc
     5701 actggttacc ttgtagcctt ctttttccaa attgaacgtc aagagcgtta caatagaagg
     5761 ttcatcatca acaactagta tttttttcat tcaaatctcc tttaaatagg tttcattctg
     5821 tttatatttt agcatagaat cagtacaaag ggctatttta caaaagaaat aaatggtata
     5881 ataggaaggc actttgctga atagaaagga agagcagtca atgattggaa tcagtgcatg
     5941 tttaggcggt ctggcctgtc gctatgatgg acagaaaaaa gaagtaccag aattgatgga
     6001 actagttgaa actggagaag ctgtcatggt ctgtccagaa gtgatcggcg gattaccaat
     6061 tcctagagat cccgctgaaa tcattggtgg aaatggattc gatgtgtgga aagatcaagc
     6121 aaaagtatgg acgacaagcg gcgaagatgt aacggaagcg tacaaaaatg gcgcgatcaa
     6181 agcctatcaa aaattgcagg aaaaacacat tgatctagtc atcatgaagg aaaaaagccc
     6241 ttcatgcgga acccattcga tttatgacgg aagtttttcc ggaataaaaa aaaatggtgc
     6301 cggagtggct actgcttatt ttattcagca aaaaatgact gtgctctctg atgaagaatg
     6361 gctgaaaact agaggtgagc agaatggaaa tcgaaaagac caatcgaatg aacgcgctct
     6421 ttgaatttta ttcgacctta ttgacagaaa aacaaatgaa ctacatggaa ttatattatg
     6481 cagatgattt ttcattaggt gagatcgcgg aagaatacga agtaagccga caagcagtat
     6541 atgacaatat caagcggaca agcaagatct tggaggatta tgaaaaaaaa ctccatcttt
     6601 tttctaatta tattgttcga gaacaggtat tggaaaatat gactgcatat attacagata
     6661 agtacccgga agataaaaaa ctacttgaat atgtacagca aattcaagca atcgaagaat
     6721 aaataaaagg aatgaagaaa atatggcatt tgaaagctta actgaacgtc tccagcaggc
     6781 gatgggaaaa ataagaaaaa aaggaaaagt atcagaagct gacgtaaaag aaatgatgcg
     6841 ggaaatccgc cttgccttac tagaagccga tgttaacttg caagtagtca aagattttac
     6901 taagcgcgta cgcgaacgtg cggtaggggc agaagtgctg gaaagtttat cacctgcaca
     6961 acaaatcgta aaaatcgttg atgaagaatt gacgatcaca cttggttctg aaacagcaga
     7021 gttaaataaa tcaccaaaaa taccaactgt tatcatgatg gctggtcttc aaggggcagg
     7081 taaaacgacc tttactggta aattagccaa ttatttaaag aaaaatgaaa atgctcgtcc
     7141 gctcctaatc gcaggggacg tatatcgacc agctgcgatc gaccaattga aagtattagg
     7201 tcaacagcta gacgttcctg tatttgatat gggaactgaa gtcagcccgg tagagatcgt
     7261 ccgtcaaggg atggagttag caaaagaaaa gaaaaacgac tatgtattga tcgatacggc
     7321 aggacgtctg catatcgatg aaacattgat ggatgagttg aaacaaatca aagaattgac
     7381 gcaaccaaat gagattttgc ttgttgtcga tgccatgact ggtcaagatg ccgtcaacgt
     7441 agctgatagc ttcaaccagc aattaggtat tacaggggtc gtcatcacta aacttgatgg
     7501 ggatactcga ggcggggcag cactatcgat ccgctcagtg acaggcgcac caatcaaatt
     7561 catcggttct ggtgaaaaat tgactgactt agaagtattc cacccagatc gtatggctag
     7621 ccgtatcctt ggtatggggg atatgctgac attgattgaa aaagcgcagc aagactacga
     7681 cgagaaaaaa gcggaagaac ttgcacagaa aatgcgggaa aattcattcg atttcaatga
     7741 ctttattgaa cagcttgatc aagtgatggg tatgggccca ctggaagatc taatcaaaat
     7801 gatcccagga atgaatcaag tccctggaat cgaaaacgtc aaggtagatc caaaagatgt
     7861 tgaacgcaaa aaagcgatgg tttattctat gacgccagca gaaagagcaa atcctgatct
     7921 gttgaaccca agccgtcgtc gccgaattgc tgccggttct ggaaacagtg ttgttgaagt
     7981 gaatcgaatg atcaaacaat tcaaggaatc aagaaaaatg atgcagcaaa tgtccaaagg
     8041 ggatatgaac atcccaggta tggaccaaat gtttggttca ggcgtcaaag gaaaactagg
     8101 caaaatggcg atgaatcgaa tgatcaagaa aaataagaag aaaaagaaaa aacggaaata
     8161 agatgaaaaa aacagcttcg gtacagactg aaaatgtcta ctgccggagc ttttctatca
     8221 gcaattttta ttctttacta atacaattac tctaaacgaa gaggtggcac agatgagatg
     8281 tccgtggagt gaacaaacag aaagtatgcg gcaatatcat gatactgtct ggggtgttcc
     8341 tgaatatgat gaccaaaagc tgttccgaaa attgatgctt gatattaatc aagccggatt
     8401 gagctggcag acgattttaa ataaaagtga agcattcgat gaagcatatg atcgattcga
     8461 tatcaaaaaa gtcgcaaatt atggagaaac aaaaatcagt gaactaatgg aaaacaaagg
     8521 aattattcgt aaccgaagaa aaatcgaagc agccgtccaa aacgccaaag cagtcttgaa
     8581 aattcaagaa gaaatcggca gtttttcaga gtatctttgg tcgttttcta atggaaaaat
     8641 cgttgattct tcttatcatt cacaagaaga agtcccaaca acaagtcctc tttcagatga
     8701 attagcaaaa gatctaaaga aaagaggatt taaatttatc ggaagcacaa caatctatgc
     8761 ttttttagaa gctgtcggga tcatcaatga tcaccttgac agttgtttcc gcaaagaaga
     8821 ggtcgtacgt atcggcagaa agggcgaata aagcatgcga aaaatcatat tttatggtgc
     8881 tataagttta gatggctatt tggcaacgaa aacggatgat cttcaatggc tttttgacac
     8941 tccaacaggt aagcaaacta cttatgaagc tttttatgaa acaatcgata cgaccatcat
     9001 gggcagaaaa acttatcagg aagcaaaaaa atatttggag accgaagcaa tttatccaga
     9061 gaaaaagaat ttcgtttttt ccacccacgc acaattacaa ttgccagatg ctgaggtcgt
     9121 aaacgaagat cctgttgctt ttctaaaaaa tctacaaatg acagaaggaa aagatatctg
     9181 ggttgtgggt ggcggtcgat tgatcaaacc gctattggaa catcaaatga ttgatgaatg
     9241 gtatatccag attacccctg tattattagg ggacgggatt cctttattcc aaaaaggaac
     9301 atatgaagcg cgttttgaaa tgctagacac gacacgattc ggtgaattta tcgaattgca
     9361 ttatgtacga aagtagaagt aaataaaata aaaaaggcaa ctatatgcag aaatgtcctg
     9421 tacatagttg ccttttttat taccgttatg ctttttactc tgttaatttg ttagaaaaat
     9481 ctagatacgc atctaaaatc gtttggaaga aacttaatgt tccttcaacg atattaccat
     9541 tttcatcaat tagattcgca acgtttccga tatatgcttc cggttgctgc aaggttggca
     9601 cattcaaaaa gacaagtgat tgtcgtagat ggtggtttgc gccaaagccg ccgatcccac
     9661 ctggtgatgc agtaacgact aaacctggtt tatgatccca aacactgtgt ccataaggtc
     9721 ttgagcctac atctaaagca tttttcaata ctgctggcac agaacggttg tattcaggag
     9781 taacgaaaac gacaccgtct agtcccctca cttcctcacg aaaacgagtc cattcagcag
     9841 gagcctgttc tggagtttcg agatcctcat tgtaaaatgg cagatcatcg atttttacaa
     9901 atacactttc gtacccttca ggaagcaatt tcgcaaaagc ttctgctact tttttgttgt
     9961 aagaatcttt tcttaaacta ccaataaaaa atccaatttt ttttgtcata cgatttttcc
    10021 tccttcaaac tatctataat aatcttacaa aagataagta actggagcaa ataaaaacac
    10081 ttactgacaa aagctacata gaagatagat tacttatttt taacaaaaaa gaagtctaaa
    10141 atcttctatt ttctaaaaaa aatcgaattt aatcaagctg taaagaaaaa aagctttaca
    10201 gggtaaaaaa aaactgttac actacatctt gtgaataaaa caatggaggt ggaaataaat
    10261 aatggcagtt aaaatccgtt taaaacgtat gggttctaaa aagagtccgt tttaccgtat
    10321 cgtcgtagct gattcacgtt ctcctcgtga tggacgtttc atcgaaactg taggtactta
    10381 caatcctttg aaagaccctg cagaagtagt tttaaaagaa gacttagttc ttgactggtt
    10441 atcaaaaggt gcacaacctt ctgacactgt acgtaacatc ctttcaaaag aaggcgttat
    10501 gcaaaaacac cacgaagcta aattctcaaa gaaataaggt gaccggatat gaaagattta
    10561 agcgacttag tcttaacaat cgttcgtccg ctagtcactt atcctgatca agtcaagtta
    10621 gacgtcgtag agtcgaaaga cttttacgag tacaatctaa cagtggctcc tgaagatatt
    10681 ggccgtatca ttggaaaaca agggcgtgtt gctaaagcaa tccgcacaat cgtttacggt
    10741 gttcggatca atgcaccgaa aaaagtgcgt ttgaatatca tcgatgataa ggaaaagtaa
    10801 ataaacgtgc tgtactcgaa ttttcgagtg cagctttttt gtttttttta ttaattgaag
    10861 aaatgattat ttggcaaaac aagcaagaaa gcgtatcctt ataggaggag ggagtgaaca
    10921 gccaatgaga aagaaaatgt tatttattcc atttgctcta ttgttaagcg cttgtagttc
    10981 ggttactcaa gaatcagaca atacacatct atcaagcagt atatctgaaa ctgttaccag
    11041 tccagaaaaa agtagtacca aaacggcttc caccactgaa caaacaatgg ctacctcaaa
    11101 taatgagaaa aagactgctt tagaccagtt gaaagaacaa cagccaaatg ttcccatgcc
    11161 tctagatgta ccagtctctt caggctatct caatatcgca gcgacacata caaagcaagg
    11221 ttattctatt ttatattaca gaacagatcg tcccctcggg ttgaatgctg acgaattgaa
    11281 tcaagaaacg cctattgcaa cctatctata tcaatatggg tttgcttcta gtcaagaaac
    11341 aatccaagtt ttgcagccat ttgagatcga cacaaatggt cagcaagtgg acttaggttc
    11401 tcgaatcaca gggtatcagc aaggtgcagc aggttcaagt tttcttgaat ggcaagaagg
    11461 aaactggcgt attcgaatcc gtgggaataa tatagaaggc caagatccct tactattagc
    11521 taaagaaatc gtagcttatt tggaagaaaa cagtctacca gcacctgaac aatttggtaa
    11581 aattactgtt gatatgggtg atacgacgaa tcgagccgta gaagtaagct ggcaagaacc
    11641 gaaaaatgcc tatacgatca ctcatcaaga tcctatgtct gcgttgaaga tggcagtttc
    11701 tatgaagagg ttgtgaaatc agcgcgctga tctgagccca tcatttaact ccaagtcaca
    11761 ggaagtaatc aaaaatagca cgccgcattt ttgcataatt ttggcttaat accttaaaag
    11821 aaaactagaa ttgcctcttc acacatgcta aaataaaaca gacaaaaaag aaatggggat
    11881 ataagttgac tgaatacttg aatgtaggaa aaatcgtaaa cacacaaggt atcaaaggcg
    11941 aagtccgtgt tatctcaaca acggatttcc cagaagaacg ttacaaaaaa ggaacggtgc
    12001 taacactatt ccaagacgga aaagcacctg tggaattaac agtcaaaagt catcgcaaac
    12061 ataaaaattt tgacttattg agttttgaag gacatccttc tatcaatgat gtggaaaaat
    12121 atcgggatgg catattaaaa gtgtcaaaag acaactctgt agatctagct gaaaatgaat
    12181 tctattacca tgagatcatc ggtctgcatg tattagaaga tggaactgag ttaggtaaag
    12241 taaaagaaat cttgtcacca ggtgccaatg atgtttgggt cgttcaacgt ccgaaaaaag
    12301 ctgatatatt gcttccatat atcgcttctg tcgtcaaaga agtcgattta gaagctggag
    12361 tggtccgtgt agaaattcca gaaggactga ttgacgatga agattgatgt attgacttta
    12421 tttccaagaa tgtttgaagg tcctatgggg gaatccatca tcggtaaggc tgtagataaa
    12481 ggattattag atatcaatat ctctaacttc cgcgattatt cagataacaa acatcagaca
    12541 gtagatgatt atccatacgg cggtggagca ggtatgctgc tcaaagtcca gcccatctat
    12601 gataacatcc aagccattga aaaagctgca ccggatgtca aaaaaagagt aattcttctt
    12661 gacccagctg gtaaacgatt cgatcagaaa atggcagaag aattttcaca agaagaacac
    12721 ttagtattca tttgtggtca ttatgaggga tatgatgaac gtatccgcac attagtgaca
    12781 gatgaagttt ccttaggaga ttatgtcctt actgggggag aattaggtgc gatggtcatg
    12841 atcgatgcaa cagttcggct tttgccagat gtgttaggga atcagacttc agctcaaacg
    12901 gattcttatt caaccggttt attggaacat ccccaatata ctcgcccggc agaatataaa
    12961 gggatgaaag taccagaagt attgacaaat ggaaatcata aattgattga agaatggcaa
    13021 ttaaaagaat cactaagaag gacctatcaa cgtcggcctg atcttttgga aacacttgaa
    13081 tggacacctc aaatgacgaa atttttagaa gaaatcaaga aagaagaaca agaaaaaaca
    13141 gcagatgaag ccaagtgact ttttctaaaa tcttctttac agtaggttga taatatgtta
    13201 gtattttatg gtgagtgcaa aagcacttaa ctattacgat attccgctgt gagaaaagct
    13261 cataagaata tttggaataa ggagaagaaa accatgaatc cattaatcga agaattaaca
    13321 aaagaacaat tacgttctga catcccagcg ttccgccctg gtgacactgt gcgtgttcac
    13381 gcaaaagttg ttgaaggtac tcgtgaacgt atccagttat ttgaaggtgt tgttatcaaa
    13441 cgccgcggtg ctggaatcag cgaaacttat acagtacgta aagtttctaa cggagtgggc
    13501 gttgaacgta cattcccatt gcatacacca cgtgttgcaa aaatcgaagt agttcgctac
    13561 ggtaaagtac gtcgtgcaaa attgtactac ctacgtgcat tacacggaaa agctgctcgt
    13621 atcaaagaaa tccgtcgtta atcattgtta tcagactgag aaagaaccct tggtattcaa
    13681 gggttctttt ttcttagcat gtaatttgaa caccctgatc cagttttttc tttaattatt
    13741 ggtaggggag aataatggat tagaataaat ctacctataa gtagtagtaa aaaaaagagc
    13801 actatgataa tatctttctt aagagtaacc gctttaataa aaaatccaga atattctaac
    13861 ataaatggag tattcttaga atcaaaagga gaaagaagat ggtttatact tatacggagc
    13921 aagaaaagat gaaagtttta gacacattca tgaatgatgg aaaagtaaaa caagtaccaa
    13981 gttcaacaaa aaagaaatac atcctattga aagaagtctt gaaacgcttt gaccatggag
    14041 tgacttatac agaaacagag gttaattcga tactgctgaa cgtattttct agtggcgatt
    14101 atgtcgaaca aagacgttat ctaatcacat ttggcttttt caaaagaagt tcagacggtc
    14161 gggcatatca gatgatggga attgaaaatt agaagtttta atttatactc attgaaaaaa
    14221 gttcaagtat gcgatattgg ttctacaccg catacttgaa ctttttttgt catctgtatc
    14281 tataatacaa agccaagaac gttattcaaa atatggatag ctatgataaa agctaatgag
    14341 cgattcgcag ttaaataagc aatcgtcagt aaaatcgttc caggagcgta catgaaaaaa
    14401 tcaattggat gcgttacatg aataaagata attctctttt atttgtacga ataaatacca
    14461 aaacgtacct cctaaaatta gattttggac agatgccctt taaaaagata acaagatttc
    14521 gttcttgaaa caatatatat gcttttattc caatgaggtt gtgaaaacag tattttgtcc
    14581 tgagcgttag aaaattgaaa atggggaata gcaactcgta ctttaccatt ttttaagtga
    14641 atacaagatc agctaattga acaccgttta ttcgtgatga gggacacaac actgcagtcg
    14701 acacatttct cttttatgtt caaagataac aaatatttaa aacaaagaaa aatagtagat
    14761 aatcccgtcc taactctttt attcttccct catagcttcc aaatttaagc aatacttcaa
    14821 ttaatcaagt tttatctttt tttttcaata atcgtaaaaa aagagtattt tttatttaaa
    14881 aataaaatct ttgtattaaa ggacaagact aaaataacct tagaataaaa agagaaaaaa
    14941 agccccaaac tttctataca tcaataaaat aataaaaatt aaatttagaa taacgtgtaa
    15001 aggattattt gatgattttt tattgagagg agggatgaaa atgattaaga aaactcaaaa
    15061 taaaatccaa cgtatatgtc aaaaacattt tgtttctaga ctcaaagctg tatctaaaag
    15121 aaaatactta catcccatta tgatttcgat catcttgatt tttactttct tagggagctt
    15181 atcaagtatt tatgtaaacg tttatacaga aacgtcaaat tttgctaacc aaacgacaga
    15241 ggagacaaat agtccaccct attctgaaat acagtccata gaaagcacca atcagtctag
    15301 caacaacgag acaacctcaa ccacatcctc gactcaactg attgatccga cagaaaaaga
    15361 aatcacagca gcaaaagcag caggggagaa agcttattca gaaacaggta gaagccagac
    15421 atttagtact gttgcggcca ctgcgaattt caacggacat accataccag atggatatac
    15481 agtgatatat gccaaagatg gagtcattgt tgcggttaac ggatcgatga gtgcggataa
    15541 aactgcgtta caaggcgtaa ccaaagcaat cgcttttatt gataaccgtc cagatatcca
    15601 taatctgttt attggctcca cagtaaatgg tactactatc acattcccaa aaagtatcta
    15661 tatgggggtg gctaccgctg gaaatacgat cgattcagtt acacccaatg cggataaaag
    15721 ttattctttt acaccctcaa catggggagg gcttcctgcc ggaggaggta tgagtacttt
    15781 ttcaatcggt atacagttag caaatgatat tccattcacg gggtactcga tcaaaaatgg
    15841 gcagatcgtt gatggtaagg gaaatgtttc aaattttcca acctatcaag cagcaacggt
    15901 tcaggtcaat gcgaatcgga caggaacttt ttcttataca gtcaatggtg gagcagcaaa
    15961 aatcggaacg tacgggacta cattatctgg aatccatgtg ggtgacaaag tggttatcac
    16021 tccaacagca gtaacgggct attcttttgc acaaacaaac ggttctttca cagccctaga
    16081 aagtaacgtc gatacggtga cctatacagg caaacaaaca ccaatcacta ttaagtatca
    16141 agactatttt ggacagatga ttgctccttc taaaataatg aatcttactt acggaagtgc
    16201 tgcacaagac ctgacgacta atacgcctac tatcaacgga tataccttta cagctgtttc
    16261 agcgacagaa acaaagaacc aatcagcaat gagtgtttta gctagtttag atacaaatgg
    16321 aaatgtaatc gtaaaggacg caaatggaaa acagatttct gaagtcatcc tatattataa
    16381 gacaaatgca acagtatcaa tcaatgcaaa tggcagtaag tactatgatg gtctttctgt
    16441 tgtaccgatc gttaaatatg cctttaatga taaaacagaa tcaacatccc ttttaaacaa
    16501 tgatctcagt attgatcaaa tcacatggaa tccaactgat ttcaaagcga tgaatgaaaa
    16561 gggagttgaa gtaactgcgc ctactgaaat tggaacctat acgtcttggc aattgacaaa
    16621 aagcggacta gctaaactag ctgccagaac aaactattta tttactatcg tgcagacatc
    16681 tgatgtctat acgattaagc aaatcagcgg tgcggtagag ctcagtggca gtaagacata
    16741 tgatggaaaa gcaggtgtcc cgtcaatcca tgtcaagcta gcagagggtg tcactagttc
    16801 gcttactcca gtacaagtgg cacttagcag tatggattac acagcagatg cacaatcagc
    16861 aaaaaatatg gttaatgctg gcagctatac aattaaacta acgaatagcg gaatagacaa
    16921 agtcaaagca gcaaatccca agttgtcatt tactgatata gccaacacat caggaactta
    16981 taccatctat aaagctaacg cagtgattac tgtcgatgac gctgccttta attatgatgc
    17041 ccaaagtcac tcgatttcgg ttggaaatct ccacgttacc ggtgttgtct taggcgaatc
    17101 attggattat accctaacag ttaacagccg gacagatatt ggatcacaaa tagtaacgat
    17161 tagtttaggc gaaggaagtg taaacaataa ttatacgatt atcgcaacag ataccgctaa
    17221 gttgacgatc aatccgactc tcttgcttcc ttcgacaggt gggataggtc tactgccctt
    17281 tgtcttttta ggactgatct ttattttttc tggcttcttt tattttatcc atcgtaagaa
    17341 aaaagcaggt gaacagcgat gaaaaaaaca aaaaatgtac gtgtggatat atttgctgtt
    17401 ctctttttta tcctactggt cttttttata ggttctccga ctgtgtcagc tagagaatca
    17461 cctattacat ttactttgca taatcgaatg ttcgaaagcg ataagatgcc aagtatcagt
    17521 caaaacgacg gaataaatat cccggataac tttcaaggag taaaagggtt gaacggcgtt
    17581 actttcgcta tatatgatgt ctcggatgaa ttttacaagc tgcggtcaga aggaagtagt
    17641 gtggaagacg cacaaagaaa actagcacaa aaaagtgata gtgaaaaaat actggcagaa
    17701 aatgtgacaa aaacagtaga cgaggaagag ggcattgctt cttttagtgc atcggacaaa
    17761 gatgagcaag gtcgtgacgc tgtttaccga tttgcggaaa taaagacttc agattaagta
    17821 aaagaaaaat cagcaccatt tgtcgttgtg cttcctgtga cagattcatc taatcataaa
    17881 ttgacgacca tccacttgta tccaaagagc gaacaaaaaa tacctgctgc actcacatta
    17941 acaaaaacag tagagaataa gcagacagat tttgcagatg gggataaagt tccttatctc
    18001 atcaccgtaa caattcctga gaacatcaac gagataggaa cctatacgat caaagataca
    18061 gctgatcctc agttatggct agaaccagaa acgatcgatt ttttgattgg tggagacaag
    18121 attcatacat ttcacacaca aaaaacaaaa catggttttg tcttatcaga ttctggaaaa
    18181 gatcttagtt cgtttgctgg gaaaaaatta acgatccgtt accaaatgac attgaaagaa
    18241 aacagtgaaa aaacgacatt tgataacgat gtacgtttga cgactgacaa tcaaacagta
    18301 gaaacacatc ttgccatcca aacaggaggc aaacaatttg tcaaagtgga tcggcaaacg
    18361 aaacaaaaac tagcagatgc tcaatttcta gtcaaaaaaa atgaccaata cttagcgcaa
    18421 gaaaacggga taaatcattg ggtagccaaa gatgattcaa gagcaacgat ttttacttcc
    18481 agtaaagatg gaacattttc tgtccatgga ttgtcttttg gaagttacga actagtggag
    18541 attaaaccgc ctaaaggata tatattgagt caatcaacca ttctctttga agttgaaaaa
    18601 ggcagttatg atccgcttca tcctatacca ttggaaatca tcaacgaacc aaaagcaaat
    18661 ccgacgaata atggaaaaac gccagttcag atgcagacaa atggtccatc aaatgaaaaa
    18721 aatggaggaa gctttccaaa aacaagcgaa gagatgcttg gaggtttctc aattttaggg
    18781 ttgttgctag tcctttcaac agggacagct tggttttata aaaaacaaca aaaaggaaac
    18841 aataggaggg aaataaaatg aaaaacatca aaacaaaaat atggacgttt ttaggaactg
    18901 ctatcatgct gcttcctttc gttctcggcc taggaactgc agaggtttct aggccgtatc
    18961 acctacacca gaaaatgtta cggttaattt gcataaattg aaattcactt cagcaccaga
    19021 aaatcaaata aacaacggaa cggaattgac atttccgaat agcgaaccgt tgaacggcgt
    19081 tgaattcaac gtatatgaca tcactgctac gtactatcca agtaaagaca cagcagttcc
    19141 agcagacgct acacccttcg caagtgtaac gacttctggt gaaggattag ctaacctgac
    19201 tcttccaggt aaatctgatg ggaaagatgc tgtatacgtc tttgtagaaa caccaaagcc
    19261 cggtgtcgaa acgtcgccaa atatcgtgtt aagcttaccc ttttataacc cgaattcatc
    19321 agaccctgac aaacctttag acacgattca cctatatgct aaaaatgtca tcaaagaaag
    19381 caatatcaaa atccagaaag ctgggaactt ttcaggggta gataagttag caggggcgca
    19441 attccagatc aaaaattcag agaatcaatt cgtgaccggt tttgatgaaa acactggtgt
    19501 cgctctctat gatcctgctg agtcagcgtt gacattcaca actgatactg aaggatccat
    19561 cagtgtcaat ggattaatag acggcaatta tactttagtt gaaacaaaag caccagatgg
    19621 ttatcaatta accaatccac aaaaagaaac tacttttata gtaaaaaacg gaaaattgca
    19681 acaaacaacc ggtatcatcc atggcgcaga tgaagccaat cttgggaatc caaacggtgt
    19741 agtcaatcgg gaaaatacaa ctacggataa cacgattact gtagaaaatg tccaaaacta
    19801 cggtgatttc cacttcatca aacaagatgt gaacacgcaa gaaaaattag ccgatgcaga
    19861 attttctatt ctaagagcaa aagatccaac tgttaaatta atgaaaaaaa tagcaaatct
    19921 tgcctcagga gaatacccat atgcttggtc agatgaagtc acaggttctg actgggaaga
    19981 agtgaaattg atttctgatt cagaagggaa attttcaatc gaagggctga aacaaggggc
    20041 atactgcctt caagaaacaa aagcaccaga aggctacgca ttacctaaga atgaagctgc
    20101 gtacactgaa tttacagtag atgatgatcc aacaacttct gatgaaacaa cgatcgataa
    20161 ccaacctaaa ggaatcttgc cttcaactgg tggtatgggg atcatcgtat tcatcttggt
    20221 aggtactgct ttagttggag gagcagtgat ctacttcaaa aaacgccatc aagaaacaga
    20281 agcttaaact attggaaaca aaaatcatac gataaataaa cgatagtgat tcaaatgggg
    20341 agaaaggttg tgacaagtgg tcggtctctt ggtattcgct caacaaacgg caaaatagga
    20401 ggaactattt tgccgtttgt tgagcgaata ctcaggtcaa ggcgctgatt tcacaacctc
    20461 ttcatataca tattagaaaa taggtggaca tgatgaataa aagcagaata agaatactgg
    20521 acatcttcat ggcaatcatt ttagtcgttg ggatcgggat cttttcttat ccttttgtag
    20581 aagattcact gaatgatttt cttgcccagc aaatgatcat ccattatcaa aagcaagcat
    20641 cgaataagaa ttcagaggaa ataaaaaaac agcaggaaaa aatgacaaag aaaaaccaac
    20701 agttggcaga gcaaaacgta tcaccaggga taggcagttt caaccaagca gttgatgcaa
    20761 aagcattaaa agatttacct agtaatgcct tttttatgga acatatgctt ggagtcatcg
    20821 aaatcccaaa aatcaatgtc agcttaccta tattcgatca gacaacggaa atatttttgc
    20881 aaaaaggaac gtcattattg gaagaaagtt cttatccgac tggcgggaaa aacacccatg
    20941 ccgttctttc tgggcatcgt ggactcccag aagcaaaatt atttacagat ttgcctaagt
    21001 tgaaaaaagg agaccagttt ttcatccaga tcaatggaaa gacattggcg tatcaagtag
    21061 aaaaaatcca agtggtctta cctgatgaag tagattcttt gggtatccaa aaaggcagag
    21121 atctcgtgac tttgcttacc tgtactcctt atatggtcaa tacacatcga ctgcttgtga
    21181 cggggcatcg tattccttat caagcaaaag aggcaaaaaa agcgatccaa ggaattgatc
    21241 aatggaaaaa atggaaattt tttatttggt ttatcggtat actacttgga tcaatcggct
    21301 tagtttggct actcatcgct tatttagatt ctttggccat cgctaagcga aactatcctt
    21361 tatcttttta tgtaaagaac acaaacggac gaccaatcga aggaatggtc ttttctgtaa
    21421 aaacgctcaa cggcaaacac tatattacta gagaaaaagt tccatttgtg aaagcttctg
    21481 atgaatacgg actagtgaga ttttctgatt taaaaggcag gaactatcgc ttgcaacatg
    21541 aggagctcct gcttaaaatc catgtaaaac ataaacattc gaaacagttt tcaatgaaat
    21601 tgaaaaaagg aagatataaa ctgcgaaaag aaaaagaggt gtactatttg attgagaaag
    21661 aatgaatgaa gatgtccaaa aaagcagagg gaacagacta aatgaaaaaa gagagaagct
    21721 gacgaaatgg acgtgtaaac tgctattttt ggtttactat ctggaacgcc agcttctatt
    21781 tttttatgtt tcagaagaat tttattatta tagtataact tttgaattag tttccataac
    21841 atttggagca aggggttaaa ccacgagctt gagcttcgct taaagtggca ggggtatacg
    21901 taccatttcc acatttatgt gtatggtatt ttgaaccggt cggtgtgaca tagacagttt
    21961 gttcattatt ttgctcagga gctgcggctt gtgcctgctg agaggcctgt tcagctgctg
    22021 cttgctgtcg cgcctgttct gcttgttgct gtgcgattgc ttcttgttgc gcttgttctg
    22081 cttgttgtcg tgcaatttct tcttgctttt tccgttcttc ttctgcttct tttgctttga
    22141 ttgtggaatc aattgcagca agacggcttg tcaactcttg tttgttttca ggtagcgctt
    22201 ggatagctgc tgaagcagtt gcatagtttt cttttgtagg atttgcttca gcttgtgaca
    22261 aagcagattc cgcttctgtc actttttttt ctagtgcagc tttttccgct ttttgtttct
    22321 cttcttcttt tttcttttca atttgttctt gttctttcga tgaatctgcc gtactttcgg
    22381 agatcgtggt actgctgctg gaagcctgag ctgaacttgt gctttgagta gtagacgtag
    22441 tagcaccaca cccactcaac aaacttcctg cgaccaaaaa caatgcaact aattttttca
    22501 ctaaatttcc tccttaagta aaaaacaacc gttttcaata aatgtccttt tcaattgttt
    22561 acttacttgt tataataatt gtgttatgaa tagtgattga ggaaacttaa tctaatcccg
    22621 ttttgataca cgggattttt tgctatagtt ctgttattaa gtatgcaata ataaaatatg
    22681 tacgttattt tattattaga ttattgacat ttatataata aacgattaaa tgattcatat
    22741 caatagaata cttaggaaaa aaagagaaat aataacaggt ttatgcacta ttgacggtgt
    22801 gacaatatga tatttgtatc cgtttttttt cttgtatgta gtatagtaaa gtagatacag
    22861 gaggagaaaa tatgcagact tttttaacaa aagtttctca aaagaaaatt aaaatgattc
    22921 atttactgct tgaaacagaa cgttggtgtt caatagaaga actacaaaac gaattgaagg
    22981 tatcaagtaa gtctatcttg aattatctaa cagatttaga agaattgttc caaaaatatc
    23041 ctgataaggt cattttgaag aatgagaata atcggcgctt ttctatggaa aagcaggaga
    23101 acttcccaat ctacattatt tatcttcatt tctacagaaa atcatataat tatcatttga
    23161 ttgaattcat gtatcaacat cctgagaaaa atttggaaga ttatgcagac gctcaatata
    23221 cgagtgtatc cacagttttt cgttatgcta agttattagt aaagtacttt gaaatgacgg
    23281 acgtcaaaga atagtagccg ccagatagaa ggaaattagc agttgaaaaa gctgccctgc
    23341 atcaagtaat acgaccagcc aaacggaaac agtgtctcat gtttttgatt tggctggtct
    23401 tattaccgca gatgcaagct tttgccacac ctctttcttg tcatttacag actcaactat
    23461 caatgctgca agctttccct taatgctgta acaccagtaa gagttgtcaa gaccagcaga
    23521 ctgactaggt aaataccgct caaaaacaag attacggcag ttaaactata atgatccatc
    23581 aagaaaccga tgacgataga agaaaaacca ccaacagctc gtccaaggtt cataatgaaa
    23641 ttattcgccg tcgcgcggat ttctgttgga tacaaactac taatcactgc gccatatcca
    23701 ccatacatgc cattgataaa gtagccgact atcacagcgg ctgctaccaa actccactgg
    23761 ctatgggcta acacaagtag atagacagat aaggatgaac aaattaaaaa caaagaaaag
    23821 gctagtttag gccccaattt atccatgatt atgccaaaag tcatcatccc caaagacatg
    23881 cctaaaatag tactgaccat ccacaatgaa gacccagaaa ccgaaagccc taatcgattt
    23941 tgcataattg aaggcagcca attcattaac ccaaaatagc cggcaatttg gacagttacc
    24001 atgatactaa ggccacatgt ttgccaagca agatgttttg attcaaacag tctgctaagt
    24061 ttggttttct tttcggcaga ttgtacagat ttgaattcct ttggttcagt caagccgcga
    24121 cgaatgaaca agaccatcaa caccggcagt acacctacga catacaacat cttccaacca
    24181 aacgttggaa tgatcacagc agctaaaatc gcagccaaag ccgcaccgac ctgcgcacca
    24241 ataccagcaa ccgaagaagc tcgtccaatt tgtttttttg aaaaactttc ggaaatcaag
    24301 gacatacacg ccccgtattc tcctcccgct cctacacctg cgataaagcg aaagagataa
    24361 accaagtaga tgtttgaagc aaaatacatc aataaagaag caatcgaaaa cagaaggacc
    24421 gtttgagaaa atactttcac acgtccatat ttatcagcta tgatgccaaa aaaaatacct
    24481 ccaatgagca tccccaaatt agtgatcgtt gaaatgaaac ccgcttgcgt accactaata
    24541 tgaaaagaag taatcattga agataatgaa aaagctaaaa acataatatc catattctct
    24601 aaagcaattc ccgccgatgt cgataataat aactttcgct gatacgttgt catttttata
    24661 ccccttttcc taaaatttcc ctaaattgtt aaaagtatat ccaaaaaaga ataaaaaaac
    24721 aagacttttt tatttgaaat aatacacaaa caaccgatat agataatcca gcttagtttt
    24781 aatagaaatg agtattgact tggagtacac ttaaagttgt agaataaata aaatacataa
    24841 gtaaagtggc aagaaattaa gagaaagagt gatcagatga atatcaaaca agtcagtgaa
    24901 gaaaagggca tttcggccga tacattgcgc tattatgaac gaatcgggtt gattccacca
    24961 gttaatcgga caaaaggcgg aatccgtgat tatacagaag aagacctaaa atgggtcgac
    25021 tttacgatct gtatgcgaaa tgccggatta tcgatcgagt ctttgattga atatattcgc
    25081 ctatctagcg aaggagaagc aactgtattt gagcggcgta agcttttgat tgaagaaagt
    25141 gaacttttga cgaaaaaaat tgctgaaatg caagaatgtt tggaacgttt acaaggaaaa
    25201 atcaagaaat atgatcgtgt gttatctaga aataaaatgg aatgtatcaa gtaaaaaaat
    25261 caaggagcat cgctatggag ttacgcttac taaaatattt ttggacaatt gcagaagaag
    25321 gaacaatctc tcaagccgca gaagttctac atcttacaca accaacctta agccgacaac
    25381 tgaaggagtt agaagaggaa ctaggaacag aactgtttgt acgcgaaaac cgcaaaatga
    25441 tcttgacaga agcaggttat tttctaaaaa agccgagcag aagaaatttt agatttaacg
    25501 aatcaaacca ctcaagaatt cgagaacaga aaaaaacaat tattcagcgg ccgatttacg
    25561 atcggctgtg tggaagctga taattcgaat acattggcac tattactaga aaagttgatc
    25621 cgtgattatc ccagcgttca atttcatatc cacagcggaa caagtgatga tatcacggag
    25681 tgactagaaa aaagcctgtt agatttagcg attttgctag atccagtaga tacagagaaa
    25741 tacgaaacga ttttgttacc aagaaaggaa aaatggggat tgctcatttt agaaaattct
    25801 gttttagcaa aaaaagacgt gataacaaaa gaagactttg cgaatgtacc tcttttgatc
    25861 tcaaagcgtc cagaaataca gcgaatgttt gctgactggt taggcataaa aaaggagcag
    25921 ttgctgatca caggaacgta caatttgatt ttcaatgtat ttgcgctaat tgagaatcag
    25981 gtaggtgctg ctttagtcat agaaggtgct gtaagtcatc tttcaaagcg agtgacattc
    26041 gttccgcttg acccaatgat tgaaacgaac tgcatgctag tctggaaaaa gaatcggatt
    26101 ttatcacctg tagtcaatga attgattcac cgtttcaaag aagcttttga acagtaataa
    26161 gtatctctaa tcgaagaaat ttcaatacaa aagcgagacg tatgacagtc ttgcttttgt
    26221 attttttcat ttttaaatca aaaaaaataa agagatttac ataacttgtt aaataagcgc
    26281 ttacaaacat aagaagaacg gaaatgaatc agctataata accgttgttc tggattgtaa
    26341 tcattacaaa gaaatgaaga ttataacttt ggaggtgttc gaaatgaaag aaaaaaagca
    26401 aaaattcgtt caaaaaacat gccctttatt caatggttgg gtatgattct gctgattgta
    26461 ttagctttat tgacgatcat tcctttttta tggatggttt ctgcttcatt caaagcaaat
    26521 aatgaagtgt tcacgattcc gattcaatgg atccctaaaa cttggcattt agagaattat
    26581 ctggttattt ggtctcgtat tcctttagtg acatttttta agaatacagc ttttttaagc
    26641 gttgtgatca cgttgattca gttgtttact tctagttttg ctgcttacgg gttttctaaa
    26701 ctaaatttta aagggcgcga tattttattt ttagcatata tcggcacgat tgctgtccct
    26761 tggcagtctt atatgatccc gcagttcatt atgatgagaa aagtgggttt aacatatacg
    26821 ttgtggtcgt tggtgctatt acaagcgttc aatgcttttg gtgtgttctt gttgaagcaa
    26881 tactacagta gtatcccaga ttctttatgt gagagtgcgc ggatcgatgg cttatcagag
    26941 tggggaatct atcgcaagat cattttacct cttacaaaac cggcgattgc cagtttgacg
    27001 atcatcacat tcgttaatac atggaacgat tatatggggc cattcattta tttgtcttct
    27061 acggaaaata aaacaatcca gttagggttg aaaatgttta ttgggctatt tgatgcagag
    27121 tacgcattaa tcatggctgc ctcagttgtt tctgttcttc ctgttgcttt tatattttta
    27181 gcgatgcaaa aatattttgt agaagggatc gcttcatcag gaatgaagga ataggaggtg
    27241 attatgaaag agcagcgttt tgacaaaaat gtttatatgg aattctttta ttggttgtat
    27301 caatcattgg caagtagcct ttgtttttgg tgtgtcaata tcttgtatat agcagctgcg
    27361 ttccttttgt cgatagatgg aaggaatgtc ttttccttta ttttttcttt actttttatt
    27421 ggtccaggtt gcatcgtgat gataggtatg acagaagaat tagcaaaaga aaaaagtttt
    27481 tcaccagtac gtttgttcat aaagacgttt cgccaatttt ggctaaaggg atttttttat
    27541 tggctatttg cttggatagt tagtgtgata atgatttttg attgtttctt ttttatacgt
    27601 ttttcttatg gaaaatggtt gattccgttg tttgttttac ttgcttgttt atcagtttcc
    27661 tttagcatca actactggta ttttcaggtg agaaatccag cgtcgaaacc aaatcaagtt
    27721 ctacggatag cgttctacta tacgttgaaa aaatggtatg tgagtttact agatttttta
    27781 ctattgacaa gtttgtttct cttctttttc gtaaagcccc aatggtgtat tctactaggt
    27841 ccttctatcg tatttggttt gatttacttc aacaatcgta aattgatgag aactatggat
    27901 ctgtagactt tataaattga aactttcaat taagaatgac agtttttatg taaaaactgt
    27961 cattcttttt cattttttga aacatatggc taaacaaatg aaataaaacg tgctatactt
    28021 ttgaatgaaa caggtttaga aactgtatca attatttgtg attatttcta actaataatt
    28081 aaaaataaag cataaaaagg acgatgttca atggacgaaa aaatgaaaca aggttcgaaa
    28141 tctgtagtag aaagtttgat taatcatcat gttgattatg tattcggtat accaggtgca
    28201 aaaatcgatg gtgtatttaa tgaattagag gatcaaggtc ctgaattaat cgtgactcgt
    28261 cacgaacaaa atgctgcatt tatggcacaa gcaatcggac gtattacagg agagccagga
    28321 gtagttatcg caacaagtgg tcctggtgct agtaacttag ctacaggttt ggtaacagcg
    28381 acagcagaag gtgacccagt tttagcaatt gccggacaag taaaacgaag cgatctattg
    28441 aagttgaccc atcaaagcat ggataatgca gcactgttcc agccaatcac aaaatacagt
    28501 gcagaaatcc aagatccaga aacaatttca gaagtgattg ccaatgctta tcgtatggct
    28561 aagagttcaa aaaaaggcgc gagctttatc agtatcccgc aagatgtagt ggatgcacct
    28621 gtccaaggga atgtcatcaa gccattgagc gatcctaaat taggttctgc ttctgcagat
    28681 gatatccgtt acctagctga acgcattaga gaagcaaaac taccggtact attagtaggt
    28741 atgcgaggat caagtgaaaa agaaacgtta gccatcaggc aattagttgg aaagacagca
    28801 ttgcctgttg tagagacatt ccaagcagct ggagtgatct cacgtgaatt agaagcgcat
    28861 ttctttggtc gtgtgggttt atttagaaac caaccaggag atatgctttt gaaacgaagt
    28921 gatctagtta ttgctattgg ctatgatcca atcgaatatg aagcaagaaa ctggaatgcg
    28981 gaaaaagatg cgcggatcat tgtgatcgat gaagcgccag ctgaaatcga tccttttatg
    29041 cagcctgaaa gagaattgat cggtgatatc tcagccactc ttgatttatt gacaggttca
    29101 ttagagcctc aacaagtgtc agaagatgca aaagaatatt tagcatctct tcaagcagaa
    29161 ttaacggagc gggacattgt tcaatcaaaa ggagaagcag gtatcttgca tcctttagaa
    29221 gttattaaca cgcttcagtc aaaagtaaca gatgatatga ctgttaccgt agatgtaggt
    29281 agtcattata tttggatggc acgccacttt agaagttatg aacctcgtca tttgttattc
    29341 agtaatggta tgcaaacgct tggtgttgca ttgccatggg cgatttctgc tgcattggtg
    29401 cgtccaaata cacaaatcgt atcagtttcc ggcgatgggg gatttttatt ctctgcccag
    29461 gatttagaaa cggcggtacg taaaaaattg aatatcgttc atttgatttg gaatgatgga
    29521 cactacaata tggtagagtt ccaagaaaaa atgaaatatc agcgggcgtc aggtgtagac
    29581 tttggtccag ttgattttgt gaaatatgca gaagcttttg gcgctaaagg aatccgagct
    29641 acaagtgtag aggaattaga aaaagcttta gaagaaggat ttgcgacaga aggacccgta
    29701 attattgata ttccgattga ttaccgtgat aatgagaaat tgggagaaac aatcttacca
    29761 gatcaattct attaaggaag tgtcgacatg actgaaaaaa tcttatacca gcacgggaca
    29821 ttaggagctt tgatggctgg cttgatggat ggaacagaaa cgattgctca tatattagaa
    29881 aaaggaactc tgggattggg aacattgcat gggcttgatg gtgaagtcat ctttttagat
    29941 ggcgtagctt atcaaggaag atcagatggc tcagttgccc aattagatgg aagtgaactt
    30001 accccctatg cagcaattac agattttacg ccagatacta gtttttctgt ctcaaaaact
    30061 gcagatggag aacaattgaa aaaagacata ttagtaagag aagccgggga aaacctattt
    30121 ttggcagtga agataactgg attattcaaa aatatgcaca tccgtatcat gccgaagcaa
    30181 gaaaaacctt acagaagact agcaaaaatt tcagagtctc aaccagaatt ccaacaaagc
    30241 aatgtccaag gaacattagt cgggttcttt acgcctgaat tattccaagg agttgctgca
    30301 gcgggatttc acttgcattt tatcgatgat acacatacat ttggcggaca tgtaatggat
    30361 tttgaagtgg ctgaaggaaa agttgagatt agccgcatct cgtcccttgt acagcatttt
    30421 ccagttgatg atccgacttt tgttcacgaa acgattgatt atgctgattt agcagcagaa
    30481 atccaacaag cagaatagaa aaagacagcg agatgcgttc aaggtgatta acctgacgta
    30541 tctcgttttt ttgaggagga aacctagcgt ttacaaaaaa actgagctat aatcttctcc
    30601 atagatcaaa aaggagcggt ttttatcatg tggacagaaa aacagaaaaa agatgcatac
    30661 gaaattttat tattacagca acaaggatta ttagaagcag aagataactg gttagcaaat
    30721 ttagcaaatt catctgcatt gttgaatgag actttgcctg agactgtctt tgcaggatat
    30781 tatttattcg atggtaatga attgatttta ggaccgttcc aagggcgagt ttcttgcaca
    30841 cgtatcaaga tgggaaaagg agtttgtgga gaatcagctg aaaaacaaga aacattgatc
    30901 gttgatgatg tcaaaaccca tgcaaattac atttcctgcg attcagccgc acaatcagaa
    30961 atcgtagtgc caatggtaaa agaaggtaat ttaatcggtg ttttagatat cgattgcgga
    31021 gtaacgaaag ggtatgatga aatcgatcaa gcatttctag aaaaatatgt agatctttta
    31081 ttagcaaatt ttaatataaa tgctttttca tttattaata actaaaatcg tctattgaaa
    31141 caaaaaagaa gagaaatcaa gaataaaaag agccggaaag acagtgggca tttctgtttt
    31201 tcggtttttt tattttttta taaaatcaca agtgttattg attttcataa tcatatttta
    31261 atggtattat cattttaaat aatggaaaaa cattaaggat ggatgaaata tgaataacga
    31321 aactatcatt ttaggaaaaa aatatatttg ccaacctatt ggcttgaaac aaaaagtggt
    31381 tggagaagta atcagtaaat tagaaaattg tgttgtgatc tgcgtagacg aatatcatga
    31441 cgtcgatcgc aatgaaatat tagaaaaatg cggaaaagta gtggcaaaat atactcacgt
    31501 ttatgagttg gaaacaacag aatatctata taactatagc aacaaatatg aacatacttt
    31561 agtttcataa agatttaaat aaagtgcctt caaaagcgag aagaccaagc ttttgaaggc
    31621 actttattta gttggcagtg attgttcatg atttttgatt tattcaaaag gttcgcctag
    31681 agaatctgtc tctgtaacga ggcctggtgg agaaactcga taaaaaccta tactgccaga
    31741 actgtcctat tttcggatag acaaactagt agttttaaaa agatcatccg atccaatcat
    31801 ttcaaaaaat gcaaaactga tatcaggatc atttagctca ggcttgttat cgtaaagcat
    31861 ttgtaaaggt tgcatttagt taggagtaaa cgcgaaacta tcatcattat ttgctgaaga
    31921 agatgaagaa gctaattcag agtttgtttg aaataaagga gacgtgctga cagtttcttt
    31981 accctgtttt ttgcagaggt agaaactttt atatcggaag tttctaccgg agaatttttc
    32041 tcatttgtag aaattgttga atcgatacta ttcgaaattt gcgtatctga aggtatgttc
    32101 tttgatgcag aagtcccaca agcagtaagt aacaataaat ttgataaact gataaacaga
    32161 attcttttca ttatgtacac actccttata gtatcgttta gcatacacct atgctcagta
    32221 ttaggcaaaa tcaatgcaaa actatcaagt cttttatagt atctattagt cttagtaata
    32281 catatatgga gagggtgata tcccagttca aaccagatac attggttacc atctgtatta
    32341 acgattatgc ctctaaacgc tttttttatg aaaaaattta taagtgaaaa cgtaggtatg
    32401 atattatcta gaggtaattt ttttgggtat ttaaatagtt gctaggagga tag
//
LOCUS       DAMEEU010000028        30907 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.029, whole genome shotgun sequence.
ACCESSION   DAMEEU010000028 DAMEEU010000000
VERSION     DAMEEU010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30907)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30907)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30907
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.029"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(298..2373)
                     /locus_tag="PB779_001286"
     CDS             complement(298..2373)
                     /locus_tag="PB779_001286"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HDE0738819.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDVKTGRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     QEMIVTQANELAEKNHWVIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGELPQSTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISD
                     VISKDTDRFGIGLSEGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELHKAVEA
                     MKKSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2375..3292)
                     /gene="glyQ"
                     /locus_tag="PB779_001287"
     CDS             complement(2375..3292)
                     /gene="glyQ"
                     /locus_tag="PB779_001287"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HDE0738820.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRL
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARAVA
                     KIFVAEREKLGFPLLNKNTANPENMKEAE"
     gene            complement(3676..4488)
                     /gene="recO"
                     /locus_tag="PB779_001288"
     CDS             complement(3676..4488)
                     /gene="recO"
                     /locus_tag="PB779_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HDE0738821.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFRSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKSGGVICEKHWPMDEHRYHADPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKTPEKNMPEKEIPEKEE"
     gene            complement(4631..5530)
                     /gene="era"
                     /locus_tag="PB779_001289"
     CDS             complement(4631..5530)
                     /gene="era"
                     /locus_tag="PB779_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HDE0738822.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYSALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5545..5940)
                     /locus_tag="PB779_001290"
     CDS             complement(5545..5940)
                     /locus_tag="PB779_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HDE0738823.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQLDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5924..6400)
                     /gene="ybeY"
                     /locus_tag="PB779_001291"
     CDS             complement(5924..6400)
                     /gene="ybeY"
                     /locus_tag="PB779_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HDE0738824.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6417..8609)
                     /locus_tag="PB779_001292"
     CDS             complement(6417..8609)
                     /locus_tag="PB779_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HDE0738825.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIVCGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQRRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDTINKSYNDKVDKAKEDENIPKPTTEERIATLKKNFENVNAENVAFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEDQIQYLNVTTEQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNAGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8633..9604)
                     /locus_tag="PB779_001293"
     CDS             complement(8633..9604)
                     /locus_tag="PB779_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HDE0738826.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10310..11689
                     /gene="brnQ"
                     /locus_tag="PB779_001294"
     CDS             10310..11689
                     /gene="brnQ"
                     /locus_tag="PB779_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDE0738827.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGANWV
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYNSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFHPMGNLNQSAADTYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKTPFVYQVTMLFAAVPAVLDM
                     LANSPALVSQQRVVASMLEFYHHHVPFAALGLGWMVPTLLGYAGSLLFYYAYRLSGYK
                     QEANELPEE"
     gene            complement(11845..12291)
                     /locus_tag="PB779_001295"
     CDS             complement(11845..12291)
                     /locus_tag="PB779_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HDE0738828.1"
                     /translation="MSLLSRLNDDMKTAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
     gene            complement(12318..12494)
                     /locus_tag="PB779_001296"
     CDS             complement(12318..12494)
                     /locus_tag="PB779_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HDE0738829.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            complement(12656..13084)
                     /locus_tag="PB779_001297"
     CDS             complement(12656..13084)
                     /locus_tag="PB779_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDE0738830.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            13176..14036
                     /locus_tag="PB779_001298"
     CDS             13176..14036
                     /locus_tag="PB779_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HDE0738831.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPSVEFNLFRRT
                     FVTDEKTLMQALQDALEEKALVLHTLINQELIEMTRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEETD"
     gene            complement(14120..14470)
                     /locus_tag="PB779_001299"
     CDS             complement(14120..14470)
                     /locus_tag="PB779_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDE0738832.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKTKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAIIQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(14486..16213)
                     /locus_tag="PB779_001300"
     CDS             complement(14486..16213)
                     /locus_tag="PB779_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HDE0738833.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEETKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAEHSGLITIIGEEVDAAYLEEIKAV
                     TIDHELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPNGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYYAEKTISVTMSGQEGSAKISALMEKFREEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGNSSEDAAEKVAAYE
                     TIIQKMTEE"
     gene            complement(16426..17352)
                     /gene="trxB"
                     /locus_tag="PB779_001301"
     CDS             complement(16426..17352)
                     /gene="trxB"
                     /locus_tag="PB779_001301"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HDE0738834.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYEGVSRFGTENAYGIVQDIKDHGSHKEVICEDKTYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNIPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            complement(17497..18933)
                     /locus_tag="PB779_001302"
     CDS             complement(17497..18933)
                     /locus_tag="PB779_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDE0738835.1"
                     /translation="MMGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGEDRFP
                     VITGKKKMFEFDENHFYPAKIAIDMYHHYKEDIALFAEMGFKTYRMSIAWSRIFPMGD
                     EKEPNESGLKFYEDVFKECQKYGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENL
                     CRVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQIKYQAAHHELVASA
                     IATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPA
                     YALKEMERNGIQIKMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFAS
                     VKNPYLEASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDY
                     RIDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNEGN
                     GTLARSKKKSFNWYKKVIDSNGENLSND"
     gene            complement(18930..20333)
                     /locus_tag="PB779_001303"
     CDS             complement(18930..20333)
                     /locus_tag="PB779_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HDE0738836.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALKDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPTMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMNELFIAHQQYLPQFKETISRLKAEGIEVQ
                     DELARELSSNTHVMEEV"
     gene            20563..21465
                     /locus_tag="PB779_001304"
     CDS             20563..21465
                     /locus_tag="PB779_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDE0738837.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKQLMLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENNVILRTAEILKQNHVPILALTSIGDST
                     LSSMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVD"
     gene            complement(21506..23392)
                     /locus_tag="PB779_001305"
     CDS             complement(21506..23392)
                     /locus_tag="PB779_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0738838.1"
                     /translation="MGKYQELASKIVENVGGKENINGLTHCITRLRFKLKNEEKANDE
                     ILKNMDGVVTVMRAGGQYQVVIGNHVPVVFEEVIKAGNLTFDEAVSTEKMRPFDMLID
                     GISGCFQPFLAILAAGGMIRGLTALLVFLGAFDRGSGTFVMFDNIGDSVFQFMPVIIG
                     LTAARKFKVNEFVGMLLGAALMNPSLSLEALSGAAEAPLTTIFSGTIFEAPIYQTVFG
                     IPWIARNYASSVIPIIFIVLLASQIQKPIKKLVPEMIANFFVPFFTVLITMPLGFLLV
                     GPAFTFATDILMAGFETLLALSPVIYGAIVGFFWQILVMFGLHWAIVPMGLMQFSVNG
                     WQNIMTPVAVVSFGQTAALTALYFKLRNPKDKAIAIPAIVSGIVGITEPAIYGFTLPR
                     KKIFIFTCVGGALGGAYSGLMNLTSWNPGGLGIFTIPNYIRPDGDLTDVINVLIGIAI
                     AMVVSFALTFFFWKEEAGETDDRQKRSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGR
                     GILIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSEAGLELLIHVGLDTVQLEGKYFESL
                     VQQGERVKQGDLLLRFDKKKIEEEGYSLETPVIVTNYTDYLDILENQGETVGPDDALI
                     TALT"
     gene            complement(23489..24340)
                     /locus_tag="PB779_001306"
     CDS             complement(23489..24340)
                     /locus_tag="PB779_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDE0738839.1"
                     /translation="MLIEKVLNNNVVITRDERNQEMIVMGKGLAFKKKVGDPIFDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVQLNDSVYIALTDHLY
                     TAIERHKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GEKSEVGEVSEELYQVIQKKYKDTFGCVEKIADFLAEIFNYQMSTDEKMYLTIHIARL
                     VHENRCK"
     gene            complement(24798..26582)
                     /locus_tag="PB779_001307"
     CDS             complement(24798..26582)
                     /locus_tag="PB779_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738840.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYVRVRLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     ALTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSTFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQAITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPTITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLTKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGV"
     gene            complement(26582..28333)
                     /locus_tag="PB779_001308"
     CDS             complement(26582..28333)
                     /locus_tag="PB779_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0738841.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGIFSLFAVALVQLAPPKVIGIIID
                     EIADKNLSIKIISWWILLLILAALLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGCSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIIAAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     RMWEKQKLEAKIEGGEA"
     gene            complement(28475..28699)
                     /locus_tag="PB779_001309"
     CDS             complement(28475..28699)
                     /locus_tag="PB779_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HDE0738842.1"
                     /translation="MVSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            28950..30536
                     /locus_tag="PB779_001310"
     CDS             28950..30536
                     /locus_tag="PB779_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HDE0738843.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFVVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADQIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQETIEEIE"
BASE COUNT         8636 a         6636 c         5509 g        10126 t
ORIGIN      
        1 aagatcattt tgaattaatc agtcttatag ttgatttcta aattgtcata tattattaaa
       61 aatttttgcc atttaaaaag aaaagcgaca gtttaccaat aaatttcaac tgaattatct
      121 aaaagtagat cagttagttt agataattca gttgaaattg accgactcaa attacttgta
      181 taatacctag gaaaaaatta actagcacca cgggtatagt tatttatatt tataacaaat
      241 aaaccagaga aatagcctat tttgtgccta ttctctggtt tatttacata ttagaaatta
      301 ttttgtgatg atttgatcta aacttgctag cgacaaagcc atggcagcaa tttgacttaa
      361 ttgcgttaat cggttcttac gtactgctgg ttcttctgcc atgaccatcg tctgatcaaa
      421 ataattttcg atcagtgggc gaaggcttac aagctgatca taattttcgt tgatcgtttg
      481 gtcagcaaag ctttttttca ttgcctctac tgctttgtgc agttctttct ccgcttcatt
      541 ttcgaacagt tcagggtcta cttctgattg tttttcaagc tccgcttttt tcgctaagtt
      601 cacgacacgt gtcaaagctt ccatcgatgg tttgaagtct tcatctgcaa gatgctgctt
      661 gaacaattgt gctgctgcaa atacttttgt cagatctttt tgttctgcat tcaaaacagc
      721 ttcgatgaca tcatgacgaa tattcttcgt tgtcaataat tggcgcagac ggcctttgat
      781 aaagtcgatc acctgttgtt gcccttctga taaaccaatg ccgaaacgat ccgtatcttt
      841 actgataaca tcactaatcg tttcttgcag aacagacaaa ggaaaggccc attttttcga
      901 ttcgatgatc cgaacgacac cgtatgcttg gcgacgtaag gcataaggat cgtttgaccc
      961 gcttggaatc atcccaactg caaagaaaga aaaaatgcta tctaatttat ctgcaatcgc
     1021 taaaacagaa cctactgtag actgaggtag ctctccttca ctggatatag gcatgtaatg
     1081 ctcacgaatc gctgttgcta cagcaggttt ctcgcctttc agcagagcat atttttcgcc
     1141 catgatccct tgtagttcag gaaattcccc taccatgttg gttactagat caaatttata
     1201 gatttcagca gctcgttgca gatccatcaa ttcttcctca gatagtccta cttgttcgcc
     1261 aatgatacgg gcaatgactt gtacccgctg cattttctca tagatactac cgattttttc
     1321 atggaaagta acagttttta gtttttcaac gtattggtcg attgaagctt tcttgtcttc
     1381 attataaaag aattccgcat cttctaaacg agccgtcaat actttttgat tgcctcgaac
     1441 cacattttcc aattttaccc gatcaccatt acgagcagaa ataaaatgag gaagcagcat
     1501 accttgatcg ttccgtacct cgaaataacg ttgatgttct ttcatagaag tgactagtac
     1561 ttcttcagga acagaaagat atttttcttc gaagtcgcca gaaaagacag ttggatattc
     1621 gactaaattg ttgacttctt ctagtaaatc ttcgtctaga tcaataaccc agtgattttt
     1681 ttcggctaat tcatttgctt gtgtaacgat catttcttgt cttttttgcg gtgaagcaat
     1741 aacgaattgt tcattcaatt tttcttcata ttcttttgca tgcgcaaatg tcacatcttc
     1801 gcctaagaaa cgatgtcctc gagaggctct gcctgttttg acatctaaga tctcaaacgg
     1861 gattacttcg tcatctaaca atgccacgat ccagtgaata gggcggatat attcaaaatc
     1921 gtattctgcc caatgcatcg ttactgggaa agtgaggctt ttaatgacat ctgctaaacc
     1981 tgtcaatact tctttcgctt ctttgccgtg agtgtatttc gttacataga catattccac
     2041 gccttttaat tctctaaaag tgatagcatc tgtcgtcaga ccttgtccgc ggacaaatcc
     2101 ttcagctgct ttcgtccagt ttccatctgc gtccaaagca atttttttgg ctggtccttt
     2161 gacttcttct tcactgtctg cttgacgttc tggaatgttt gttactttga ttgctaagcg
     2221 gcgcggtgta gaaaacgttt cgatcgtatc ataagtcaat tggttttcat ctaaaaattt
     2281 tgctgttttt tcttctaatt gtttcatgct tggtgtgaca acatgagcag gcatttcttc
     2341 cagcccgatt tcaagtaata agtcttttgc catcttattc agcctccttc atgttttctg
     2401 gatttgctgt gtttttattc aataaaggga atcctaattt ttcgcgttct gccacaaaga
     2461 ttttggctac agcacgagcc atgttgcgga tacgggaaag ataacctgct cgttctgtta
     2521 cggatactgc accgcgagca tctaataaat tgaatgtatg gctgcatttc aaaatataat
     2581 catacgctgg atgaacaaga ttttcatcga tacagcgttt agcttctttt tcaaaacggt
     2641 caaagttgct tagtagcaag tcttggtcac ttacttcaaa agaatatttg gaatgttcat
     2701 attctggttg tttgaagatc tcgccatatt tcacaccatc agcccattcc agatcataga
     2761 cactttcaac ttcttgaata tatgaagcaa gacgttctag tccataagtg atctcagaag
     2821 taactggttt acaaggtagt cctccgactt gctggaagta cgtgaattgt gtgatctcca
     2881 tcccatcaag ccatacttcc caacccacac cggcacaccc catcgatggg ttctcccagt
     2941 tgtcttcaac aaaacgaata tcgtgttcta atggatcaat tcctaaaaga cgcaagcttt
     3001 ctaaataaag ctcttggata ttttcaggtg aaggtttcat tacgacttga aattgatgat
     3061 gctgatacaa acggtttggg ttttctccat aacgcccgtc agctggtcgg cgggatggct
     3121 ctacataagc agcattccat ggttccggtc cgattgcccg taagaatgta tatgggctca
     3181 tcgtacctgc tcctttttct gtgtcataag cttgcatcag catgcagccg tttgatgacc
     3241 aaaatttttg taatgttaaa atcatatctt ggacggtcaa ttttttactc atctgttttg
     3301 cccctttcaa tttttaagcg ttgctgtcaa taagaataca ggaaagaaaa cgacaaaaag
     3361 tccctatgtc tgattacaga catagggacg aataatttcg cggttccacc ctacttccga
     3421 ataaagattc ggcagcttca tttatcgtac tcgcaagtgc ctcttcaaaa atcgtttggg
     3481 tccggcttcc actctcccga actcgctaaa ccacgtgttt tttactgatc ttggtcaatg
     3541 tacgtattca ttttgcagtt ttcttgttta tataatagat cctctcagtg aacgatctat
     3601 ttaatctacg gttaataata gacggaagtc cctgtatttg tcaaatagtt ttgatttttt
     3661 tgttgtatct ttcatttatt cttctttttc aggtatctct ttttcaggca tatttttctc
     3721 tggcgtcttt aatacgtgtg cccaagactt catttgatca atgaactttt tgctttttag
     3781 atgaataccg acatattcat catacaactg gtcaatgagg tcacggattg cctgcttcgt
     3841 ttcttctttc aagtggattc cactgatctt atcataagaa atagccgaaa acattcgaac
     3901 gaaataaaca gcgcgaggat ctgcatgata acggtgttcg tccattggcc agtgtttctc
     3961 gcatatcaca ccgccagatt tggaagaata gtcaaatttt ccttttgttt ccccgcatac
     4021 gacacagtgc gtccaaattg gcgcgattcc gaagcgttgc agtatttgaa cttcaaagat
     4081 attcgtgatg atttctgcat catctccttg atccatccgc tgcagagctt gttgcgtaaa
     4141 ttggaataaa tgcgggtcat attgatgatc ttcgattgct gcatctacta gatttagcaa
     4201 ataggtacca taaccgctca aaaagatatc ttcttggatg ttccgaaacg catggacgtc
     4261 tttgacactg cttaaaaacg acaaaccttc acttcgaaaa ttaccgatat agactgcttc
     4321 ggtaaagggg agcaaagccg gagctaatgg ctgattttgc cgatggattc ctttgatata
     4381 aaacatcatt ttgccagaag attccgtaaa gattttgact aatttatctt tttctttgta
     4441 attacggcta gataaaatca agcctttcga ttctgcaagc tggctcatat tctccctcct
     4501 aaaaaataaa tctggaaaag cagattctgc cgatccagat tatttatgtt tcgatcttcc
     4561 gccgtttttc tcaacgtgcg gatttttatc cagtttattt ctatacttaa cctataagaa
     4621 gttcagaata tcagtattcg tcttttcggt agccaaagtc ttgcagatag acttttttgt
     4681 ctcgccagtc tttttggact ttgacccaaa gttctagaaa tactttgtct cctaaaagat
     4741 tttcgatatc ctttcttgct ttcgttccta cttgcttcag catttttccg cctttgccga
     4801 taatgattcc tttttggcta tctctttcga cgatgatcgt ggcctggata tggattttat
     4861 cattctcgtt tcgcttcatc gaatcaacaa cgactgcgac agaatgaggc acttcgtctc
     4921 gtgttaaaaa caagactttc tcacggatca attcagaaac gataaagtat tcaggatgat
     4981 cagtcacttg atcatctgga aaatattgtg ggccctctgg catttcactg actaatacat
     5041 ccattaagcg ttcgacattg tttccttctg tagcagagat cggaatcact tgtgcaaaag
     5101 gcatctgcgt cgaataatct tcgatgattc ccagcaactc gtctggatgg atcttatcga
     5161 ttttattgat aatcagataa actggagaat gcacgttttt tagacgttca ataataaaat
     5221 cgtctccccg gccgcgtttt tgatcagcac tgatcataaa taagactgca tccacttctt
     5281 tcaacgcact gtaagctgct tctaccataa aatctcctag acgatgcttt ggtttatgga
     5341 ttcctggtgt atcgataaaa atcagctgag cttctggtgt agtatatact ccttggattt
     5401 tatttctagt tgtctgtgcc ttgtcactca taatggcaat tttttgaccc acgattcggt
     5461 tcaataatgt ggattttcct acattcgggc ggccgacgat tgcgacaaac cctgatttat
     5521 gttctggcat atacgttctc ctttttaatt aaacaacaaa tgatatattt tagggacaaa
     5581 taaaatcaac ccaatgatga cagcaaaaca agcggtcact aaaactgctc cagctgccat
     5641 atctttgatt tttttcccaa tcggatgaaa atgaaaatcc gtaaacatgt ccactacatt
     5701 ttcaaaaaca gtattgatga tctctactat ccaaacgaga aaaacagcta aaagcagcca
     5761 taaccactct atccgatcaa gctggaaaat cacgcccata aataaagcaa ggataccgaa
     5821 cgcaacatgt ttcctcatat tgcgttcttc ctcaaaaacg gttttgactc cttggacagc
     5881 aaattccaca gacatcagga aatgtttgtt tttctctacg tttttatctt ttgagtccat
     5941 aggcatccaa gatctctttc tgtaaaccaa acatttcttt ctcatcttct ggtgtcatat
     6001 ggtcataccc gttgatatgc aagaatccat gtaccgctaa aaagccaagt tcccgatcat
     6061 atgaatggcc gtaagcttct gcttgttcag cagcacgttc aatagaaatc atgatgtctc
     6121 ctagtacacg aggcaaagga ttctctccat cttcaaaaat cactgggatt tcgtcttcgc
     6181 cttcttcttc cagagcaaaa ctgatgacgt ctgtcggtgc atcttttcca cggtaatcac
     6241 gattgattac ttggattgcc gcattgtcca tgaaagtaac agacatttct gtttcctctg
     6301 gcagctttaa ataagatgct gcaaattgca gcaagtcatc gatttctttc attttctctt
     6361 ctgagacttg gtttgtttca tccataaagg taatatccat tatacatcgc ttctttctat
     6421 tcttcttgtt cttcctttat cttctcaact tctgttttca ttttaggata tttgatccga
     6481 gaatggaagg tgctacttaa accgctgatc aatgattttt ccacttttcg gatttctttc
     6541 aaggtcagtc cactatcgtc taattgacca tcggaaatac gctcttcgat aagattatgg
     6601 acaaaacttt cgattttttc gctcgtcgga tgatccattg cccgtactgc agcctcacaa
     6661 ctgtcagcaa tattgacgat ccctgcttca cgactttgcg gttttggtcc aggataacgg
     6721 aattgctctt ctgttacttc cggattgcgt tctttcgctt tgatgtagaa ataacgcatt
     6781 agcgtggttc catgatgctg tttgcaaata tcgatcacca tttgcggcat attataatct
     6841 tccaatattt tggctccatc tgtcacatgt ccaaagataa tatgtttact gtcttctggc
     6901 aataagaaat tgtgcgggtt ttccgctcct gaaggcaagt tctcaacgaa aaagctagca
     6961 tgtttgatct tgccgatatc atgataatag caagctactc gagttagcaa agaacgtccg
     7021 ccgatttctg ctacagcgtt agcacttaga ttagctacca tcatactatg atgataagta
     7081 cctggcgctt cttccagcaa ctgtttcaat aaaggatgat ttggattgct gagttcattt
     7141 aatacaatta cactgtcatc attgaccatc aattcaatat atgggtgtag accgatcgtc
     7201 agcaagaatg agaagagtgc accagtgaac ccgcagacaa gcattaacca agtcgttgca
     7261 tcaccaaagc tcattccttg atagacgatc aaaatgacat ccatcatcac aggaaaaata
     7321 atgacccaca tggcagcaga taatccttgt tctgagatcc gtttgcgtct gacaatcgtt
     7381 gccatgagcc cagagaaaac ataagacatc aagataatcg ttagaaagtt cgtgccaatc
     7441 gaatcataaa aaatgaaaag tgcagatact gcttggaaaa taccagccat gatccctgct
     7501 cttcggttca agaaaaagct taaaacaagt ggtgcaaaag cagcgggata aaacagcggg
     7561 atataagtag cttgttccgt ttggaataat tggaaaaatt tcatcagcac tatgctgact
     7621 gacatagctg tcacatagaa aagcacgtat tttgttcttt ctcctgcatt ttggaattga
     7681 agtgaattat aaatcagtac gccgatttga agcaaaacag ctaaaaccat ggcaatgagt
     7741 gggaaaatcg aagtcgtttg attcgtcaat cctagtaatt ccaatttttt catcgctgaa
     7801 gcatcaattt gatttccttc gcgaacaatg atttctcctt ggaagatcat cactggttgt
     7861 acagcttctc gtgcagattg ttttaattct tctgtctttt tctcattcaa tacatcattg
     7921 actacaatgc cttgatccac taagtagcga atcatttgtt gctgctctgt tgtgacattc
     7981 aaatactgaa tctgatcttc tgcttcttgt ttaaaagctt ccaattcgct ttcacgaact
     8041 tgtttactca tctgttcgtc aatgagcttc aaactttcat ccctaaccgt gtgaatttcc
     8101 gtttcagtca tttcaaatat cgtcgaataa aaattgttcg gcagtttttg gtaaaacgca
     8161 acgttttctg cattcacgtt ttcaaaattt ttcttcagtg tagcaatccg ctcttctgta
     8221 gtaggtttcg ggatattttc atcttccttc gccttatcta ccttgtcatt ataagatttg
     8281 ttgatggtat cattcgtctt atcgatcaat tcgaataatt gcttgatccg attgttctgg
     8341 tcatctgcca gatctttttg ataagtatat tctggagtca ctgcttctgc tgccagtttt
     8401 cttctttgtt cggtttcttc cgtgttctcg atcgttttat tcgcacggat actctcttct
     8461 gctacttggc cttctctgaa atcattggcc ttttgtttga cactactaaa tgtaacgccg
     8521 cagacaatga taaaaaacaa gaacagaagg aaaggcaatg ctgcctttcc gagtttttct
     8581 tgtagtttct gcagtgtttt attcaacatg tgcttatcct cctaagcaaa gcttattctt
     8641 gatgaagatc cgccttttca taagctttga tgatttcggc aactacaggg tgccgaacaa
     8701 cgtcacttgc ttcaaaatta acaaaatcga tttttttgat ttgctttagt gttcgttctg
     8761 catgaacaag accacttgtc gtccctcgag gcaagtctat ctgacttgta tccccattga
     8821 caatcatttt tgattgataa ccgagacggg tcaagaacat tttcatctga gcgactgtcg
     8881 tgttttgtgc ttcgtccaag ataacgaatg catcatccaa tgtccgcccc cgcatgtaag
     8941 ctaatggtgc gatttcgatt acgcctcgtt ccatcaatcg gttcgtatga tccaatccaa
     9001 aaatttggta taaagcatca taaacaggcc gcagataagg atccactttt tctttcagat
     9061 ccccgggtag aaagcctagg ttttcccctg cctctacagc gggccgcgtc aaaatgattt
     9121 tttgcacttc gccttttttt agggcagcaa ttgctaatac tacggcaaga aacgttttcc
     9181 ctgttccggc tggccctaca ccaaatacga tgtcatgttt ggctaccgat tcaacgtatt
     9241 tcttttgacc gctgtttttt acccgtatag gttttccatt acggtctttg acgatctctt
     9301 cctcatacat ctcaacaaaa taatctaatg tacctttttg ccccattttc aatgccgtca
     9361 cgacatctgg tgtacttacg tggattcctc gtttgatcaa ttcctgtaat gtccgaatga
     9421 ctgaggcagc caaggaaatc tgggattgtt caccaatgat ctgaatgatt tctccacgtg
     9481 tatggatggt tgtttccgtt gtttcctcga tcagttttat atgcttgtcg tgtgcaccta
     9541 aaagcatgct gacatcatca gcagctgtca atctaatctc taaagaacta gactcttccg
     9601 tcaaaaatag acatcccctt tttttcgatt cattctttcc tattttacca tactcagaag
     9661 aaactatata gcaaataaga aaaggttgta aaagagtcgt ttaaccatac gtaccaagaa
     9721 acgttaaaaa atagctgttt ccattcgcta aaggtctcgt tttgataaaa agaatctgag
     9781 aatgtaagtt atatgaaagt ggagaacaaa atattccgtt tcattcagag gtattctcta
     9841 ggtatttttc ttgtttcaaa aaaagaaaac aaaatagtta aaatattctt gcatttcaaa
     9901 aaaaacaggt gtattattac gtcaacaaat aaacatacag caaagcgtcg aggaaaacag
     9961 taggctattc aacgatttat tcccagtgag tcatgtaagt gagaaatgac aataaatcga
    10021 atagacgaac atcatttccg agtcaatgtc gaaaacgtag atcattgtgg ctgcctccat
    10081 tatcaggcta gcggataact ttatcaaaaa gcgtccgtga atgaagaagc ttttttaagc
    10141 gaaaaaaggt ggtaccgttc tagaatctag agcccttttc ccaagtggaa aagggctttt
    10201 ttttatattt taaggtggtg gttttcatgg aatctgatat tagtggcatt actaattgct
    10261 gcaacgttta tatcgtcaat caaaatgata attattggag gaaaaattta tggaagaaac
    10321 aaaaacttat tcatggaaac aactattgat ggtcagttca cttatcttcg ggatgttttt
    10381 cgggtcaggt aatctaatct ttcctgtcca cttaggtcaa atggctggcg caaactgggt
    10441 cagtgctggc gtaggatttg ccatctcagg cgctcttttc ccattactag ctatcttagc
    10501 tgtagtagtg acaaaaagtg atggtctgta tgacttagct aaacctgtcg gaaaatggta
    10561 tgctgccttg ttcttaatcc ttgttcattt gacgatcgga ccatttttcg gtacaccacg
    10621 gacagctgct actgcttttg aaatggctgc taaaccattt ttgcctgaaa aatataattc
    10681 attaggtatg tttttattct ctgctctttt ctttttactt gcttatttcc ttactgtcca
    10741 tcccacacgg ttggtcaaat acgtcggaaa gtatctaaac tccttgtttc ttgcattatt
    10801 agcaatcatt tttgtcgttt ctttattcca cccaatggga aatctaaatc aatctgctgc
    10861 agatacttac caaacaaacg ctttaacaaa tggtgtccta gaaggttata acacggttga
    10921 tgcagtagcc ttgcttgcct taagtgtcac ttttgtccat gcagtccgtg accttggttt
    10981 caaagataaa aaagtcacag aattaacagc aaaagctggt agcctgagcg ttgcgctaga
    11041 agtcatgatc tattttggtc ttgttcttct cggtgcgatg agtttgaata agatgtcttt
    11101 atcagaaaat ggcggaactg cactttctca gatcactaat ttttatttag gtaacttcgg
    11161 cgctagcttc ttaggagtga tggtcacatt aggtgtcttc actaccgcta tgggactcgt
    11221 tgtttctttt gcacaagatt tccataaact gttccctaaa gtcagttata tgacatggct
    11281 gcggttaacg actttcgtct cttttgtcgt tgcaaatgct ggtttggaca atatcatcca
    11341 atggtcttta ccagtattga tgcttttgta tccattgtcg cttgcgttga ttttgctttc
    11401 cttaacagca aaatttttcc aaaagacacc atttgtctat caagtaacga tgttgtttgc
    11461 tgctgttccc gccgtattgg atatgctggc aaattcgcct gctttagtga gtcaacaaag
    11521 agttgtagca agcatgctcg aattttatca tcatcacgtt ccttttgctg cattgggact
    11581 tggctggatg gtcccaacgt tacttgggta tgctggcagc ttactcttct attacgccta
    11641 tcgcctatca gggtataaac aagaagcaaa tgaactacca gaagaataac cagatcaaac
    11701 acaatttaac ataagaaata ttaaacagga aaaaaacagc tagatgaaag aatcctattc
    11761 tttcgtctag ctatttttta gatctctttt ttacgagcac aaaaaaactg cggacaatga
    11821 ttgtccgcag tttaaatgat aaaattaaga ttgtaatagt tctttcacaa tggcatttac
    11881 ttggtttcca tctgcttttc ctttgacttt aggcatgatc gcacccatga ctttgccaaa
    11941 ttctttcatt gatgaagcac cagtttgcgt gattgcttct tgaacaagtt gtcgaatttc
    12001 ttcgtcggaa agttgttccg gcatgtattt ttcgactatc acaatttcac tttttacttt
    12061 ttcagctaaa tcgtcacgtc ctgcttcttc aaactcatgc aaagaatcac gtcgctgttt
    12121 catttcgcga gacaacaccg ttaattcttc ttcttctgtc aagtcgtgac cttctttaat
    12181 ctgctcgttt tgtatagatg acttgatcat tcggatgact tgtaaagatt ccttatcttt
    12241 cgctttcatc gctgttttca tgtcatcgtt taatctactt agtagtgaca cactaccaac
    12301 tccaattcat cacagaacta gaattttttg cgttttctag ctgcttcaga ttttttcttg
    12361 cgtcttacac ttggtttttc gtagaattca cgtttacgag attcttgtaa agtacccgct
    12421 tttgacacgg aacgtttgaa gcgacgaaga gcatcgtcaa gtgattcgtt tttgcgaacg
    12481 actgtttttg acatgttaat tccctccctc cgagcttaaa aagtaaccgt aattgttatt
    12541 gaaatatatc tcaaaaaaca agactgtcct gtaaatatta tatctaatgc tgttttgacc
    12601 gtcaaggaaa tcttgctttt ttttaaaatt atcaaatgtt attttattta aatccttatt
    12661 gacaattttc acatcttccg aaaatctcga atctatgccc ttcgatcgta catccaccga
    12721 gctgttcttc gaaataattc attggacaca tatggatttc tttcgttgtt ccgcacaccg
    12781 tacagataaa gtgatggtga tggccgattt ccccttgaca gcaatgaaaa cgaaacttca
    12841 tctctccatt taaatcggtt tcttccagta aatcgatttc tgcaaaatca tggagatttc
    12901 gataaatcgt atcgtaactt actcctttga attcctgatt catatagtca aaaacttctt
    12961 tagcggatac gtagcgattg cgcttcacta aataagttaa caatgcttct ctttttttag
    13021 tatatttaaa accgttattt ttcaatgttt ctagtgattg ttcgatcaac gtctgttttt
    13081 tcatgactta ttcctccaaa tcaaaatgat tacgaagtac acattctaga gtatggtata
    13141 ataaacataa aaaaaatgca agtgaggttt tatccatgtc ttccgattct acagaaatcg
    13201 ttactttttt tgtcatctcc gactctgctg gagaaactgc gacaaaacta gcgcaagcca
    13261 ctatggccca atatcctagc gttgagttca atttattccg cagaacattt gtgacagatg
    13321 agaaaacatt gatgcaggca ctgcaagatg cactagaaga aaaagctctt gtcctgcaca
    13381 cattgatcaa tcaagaattg atcgagatga cgcgttcttt ttgtgaagaa catcaattat
    13441 ttagttttga tgtgatgact ccgccgatat cagaaatcga gcgcttaact ggtatcaagc
    13501 ccattcggca acctggcgcc cttcatttat tgaatgagaa ctatttcaaa cggatcaaag
    13561 caatggaatt tgctgtaaaa tacgatgacg ggaaagatcc tcgtgggttt ctagaagcag
    13621 atgtcgtttt gctaggcgta tcccgaactt ccaaaacgcc tttgagcttg tttttagcta
    13681 acaaaaattt aaaagttgcc aatctacctt tgatcccaca agcacatatt cccaaacagc
    13741 tttgggagat cgatcctaaa aaaatcgtgg gactgacgaa taacccagat attttaaaca
    13801 atatccgtaa agaacggatg cgctcttacg gattaaatcc tgatactgct tattccgata
    13861 tcgaaaaaat acgagctgaa ctcgattttg cgaatgatct ttatgaaaaa ttgggctgcg
    13921 tagtaatcaa tgtcgcttct ttatctattg aagaaacagc ttcgcttatt ttgaatgctt
    13981 tagacctaga agaccatagt tattatggaa ctgaaaccac cgaagaaaca gactaacaat
    14041 ttttctttaa aaaaactgga ctgtgtcagc gaagaagatt cgttgacaca gtccagtttg
    14101 tctctatttg cacctatcgt tattgatgtt ccacatgttt gagtgtctgg ttcaaaatat
    14161 ccagtacgtg agaatcatca agactataca aaatcgcttt tccctcacga tgggacttga
    14221 cgacatggtt ttctcttaat aaacgcagtt gatgcgatac agcagattgt tccatttcca
    14281 ctgcttggat gattgctgtc acattttgtt ccccgtcttt cagatacagc agaattttga
    14341 gacgagtggg gtcactcaac attttgaata gttggctgac tttctctact tttgtttttt
    14401 gcgtgtctgg caatccattc acctccaact tgaaaaaaga ctgacttcta aagtttacca
    14461 ctttttccat cagtctcaag tttttttatt cttctgtcat cttttggata atcgtttcat
    14521 aagcggctac tttttcagct gcgtcttctg aagagtttcc ttttacaccg atataaaatt
    14581 tgattttcgg ctcagttcct gaaggacgga tagcgatcca gccattttct tccagcgtat
    14641 acttcaatac gtcagatggc ggtgtcgtta gtttttctac gtttccttca cggtctgttc
    14701 tcgtcaactc tttgaagtct tctgtttgga tgacttttgc tccggcaaat tctgttggtg
    14761 cttcttcacg gaatttttcc atcaaagcag agattttcgc agaaccttct tgtccgctca
    14821 ttgtcacaga aatcgttttt tctgcgtagt agccataggt ttcaaaaatc gtttgcaagc
    14881 catcatacaa cgttttgcct tgttttttat agtaagctgc tacttctgct aataagagca
    14941 atgcttggat cgcgtctttg tcgcgaacga aaggtttaac taaataaccg taactttctt
    15001 cgaatccgaa cataaaagta tgggaatgat cttcttcaaa ttgttgaatt ttttcagcaa
    15061 tgaatttgaa tcctgtcaat acattgaaca tggtagcccc atagtgttcc gcaattgctg
    15121 taggtaattc gctagaaacg atcgatttca ataccgctgc gttttcaggt aaagtgcctc
    15181 gcgattggtg tgcttccaaa atatattgag caaacagtgc tccgatttgg tttccggtca
    15241 atacttcata ggagccattt ggcaaacgaa cggctgcacc taaacggtct gcatcaggat
    15301 ctgttgcaat cagcaaatca gcgccttctt tctcgccaag tcgtatcgca tactcaaaag
    15361 cagagtgttc ttctggattt ggtgatttga ctgtagtgaa atctgggtct gcgacagctt
    15421 gttctggaac tagtacgaat tgttcgaatc cagcttgttt caacgcacgt tcgcccaaca
    15481 tttttcctgt tccgtgaagt ggtgtgtaca caagtttcaa atctttcccc attgtttcca
    15541 ccaattcatg atcaatcgtt actgctttga tttcttctag ataagcggca tccacttctt
    15601 ctccgatgat cgtgatcaat ccgctatgtt cagcttcttc gtcagataat acttcaactt
    15661 ttaacggatt gctgacttca cggacatatt tcgtcaatgc atctgcgtct gcaggaggca
    15721 tttgtccccc atcttctccg tagactttat atccgttgta agctgctgga ttgtgggatg
    15781 cggttaccat gattcccgca aacgtcttca aatgacggac tgcaaaagaa agctctggtg
    15841 ttggacgtag actttcgaat acataagatg ggatattgtg atgtgctaat gttttggctg
    15901 cttccatggc aaattctggt gattgatggc gtgagtcata agcgatagcg acacctcggc
    15961 gttttgtttc ttcgccttgt gtatccatga aacgtgcaag tccttctgtt gcttgtctta
    16021 ccgtatagat gttcattcga ttgatcccag gccctaagat tccccgcatg cctgcagtac
    16081 cgaattccaa cggtgcataa aaagcatctt caagtttttc aggatcttca cccagatcat
    16141 ttaattgttt ttttaagttt tcttctaaat tttcttcatg tacccattgt tcatacactt
    16201 gttcccaaga catgaaaata acacctcttt ctgaaatatg gttcttaata agtatagcat
    16261 tcacttatta gatatgaaag tatgaggacc aaaaaacgct taaatcaaga aaggattctt
    16321 ttatcaagca cggttgcaag tattcgcata aatcggattc agtagatttc acgcgaaaaa
    16381 aaagagtaaa agaacaatta aaccgttctt ccactctttt taaacttatg cagttgtttc
    16441 ttctaaagat tccaagtatt tatacacttg ttgtccagcg atcccaccat caccaacagc
    16501 agtagtgatt tgtcgcaaat ctttttcacg aacatctccg atggcaaaaa cgcctggtat
    16561 attcgtcttc atttcgttgt ctgttggaat ccagccagct tcgttcgtca accctgcttc
    16621 tctaaatggt gcagttaatg gatccagtcc aacatagatg aatactccgt ctgctgccaa
    16681 atcaaactca ttgccggttt tgacattacg tgctttcaca cctgtcacta ccatttcatt
    16741 cccaacgatt tcgtcaacga ctgtatccca cataaaggaa attttttcat tcgcaaatgc
    16801 acggtcttgg atgatctttt gtgcacgtaa ttcatctcta cggtggacga tgactacttc
    16861 agaagcaaat tgtgtcaaat agatggcttc ttctactgct gagtctcctc ctccgatcac
    16921 tactagacgt ttgttacgga aaaacgcacc atcacaaact gcacagtaag aaacgccacg
    16981 tccagcaaat tcttcctcgc caggtacgcc taatttacgg tggatacagc ctgttgcgat
    17041 aatgactgtt tttccttcgt aagttttatc ttcacaaata acttctttgt ggctgccgtg
    17101 atccttgata tcttgcacga ttccataagc attttctgtc ccaaatcttg aaacaccttc
    17161 atacatctta taagctagat caggacccat tattgaatcg aaaccaggat agttttcgat
    17221 ttctgccgta ttgttcattt ggccgccagg ggcgccttgt tcgatcatca atacggataa
    17281 gtttgaacgt gaagcatata aagcagcagt catcccagca ggacctgcgc caataacgat
    17341 tacatcatac atatgtagat tctcctttac ttaatcaagt aagcatactt tacagccaat
    17401 gcgaaaaaaa gtctattgtt ctgcttgcgt ttctcgaata gctttattat actcgaaaaa
    17461 tccgctgaaa aacaatagac ttttataaat cattgatcaa tcattcgaaa gattttctcc
    17521 atttgaatca attacttttt tataccagtt gaatgatttc ttcttcgaac gggctaatgt
    17581 gccatttcct tcgttgtcac gatcgacata aatgaatccg taccttttct tcatctcacc
    17641 tgtaccagct gatactaaat caatacatcc ccaagtcgta tagcctaata gatcgactcc
    17701 atctaattct actgcatctt tcattgcctg gatatgtgct gccagatagt cgattcgata
    17761 gtcatcttcc acataaccat tctcatcggg cgtatcgact gcacctaagc cgttttctac
    17821 aataaatagt ggtttttgat aacgatcata aatatcattc atcgttattc tcaagcctaa
    17881 tggatcaatt tgccaacccc attcacttgc ttccagatat ggatttttga cagaagcaaa
    17941 gatatttcct gcagtctgtt ccaagagttc gttgtcagta gtcgaaactc gagaagaata
    18001 ataagaaaag gagataaaat caacagtatg ttctttcagc aatgcggcat ccccaggttc
    18061 cattttgatc tgaatgccat ttcgttccat ttctttcaat gcataagcag gatattctcc
    18121 tcgtgactgg acatcaatga agaaataatt ttctcgatct gattttctag aagcccaaac
    18181 atcttcagga ttgcaagtgt atggataata tgctcctgct gccagcatac agcctacttt
    18241 gttctccgga tctacttcat gagcaatctt cgttgcgatg gcacttgcaa ccaactcatg
    18301 atgtgccgct tgatatttga tttgttcttc attttctcct tcttcaaaat acagccctgc
    18361 gcccatgaat ggtgcatgaa ggatcatatt gatctcattg aatgtcaacc aatatttgac
    18421 aagtccttta tagcgattga agatgactcg gcacagattt tcataaaaac caacgagttc
    18481 tctggaacgc cacgcaccat attctttgat caaatgcatc ggacaatcaa aatgtgtaat
    18541 cgtcacaagc ggctcgatcc cgtacttttg acattcttta aagacatcct cataaaattt
    18601 caaaccagat tcatttggct ctttttcatc gcccattgga aaaatacgac tccaagcaat
    18661 ggacatccga taagtcttga accccatttc tgcaaataaa gcaatatctt ccttataatg
    18721 atgatacata tcgatcgcaa tttttgctgg ataaaaatga ttttcatcaa attcaaacat
    18781 tttctttttt ccagtaatga caggaaaacg gtcttctccg attggcacaa catctacgtt
    18841 cgctaaccca cgtccgcctt catcataacc gccctcgcat tgattggctg ctgtagctcc
    18901 gccccataaa aaatcttttc tgaatcccat catacttcct ccattacatg tgtattgctt
    18961 gataattctc ttgccagttc atcttggact tcgattcctt ctgcttttaa ccggctgatt
    19021 gtttccttga attgcggtaa atactgctga tgtgcaataa acaactcatt catgatccgt
    19081 tttgctgtct ttcctgatcg tataagcgga ttgatcgtaa acgcttgtaa agctgttcca
    19141 taatcaccag tcacagctgc ttcgatcgtc agcaattcca tattcttcat tacttgcaac
    19201 cagcctcttt cagcagcagg aagggaacca aacgctacat ttcgtgcgcc ttgtgcgcca
    19261 acataggcag tgacttctac tacacaatct gccggcagat caggaacagc tccatcattc
    19321 tttgtagata ccacgatctg tgtttcttta tttccataga tcgaagcaat cgtttcacag
    19381 gcagcatctg aataataagc accacctcgt ttttgcaatt gttcaggttt atgatccaat
    19441 tctggatctt tgtataattc aaacagctct gcttctgttt ctttcacttg ctgcgctctt
    19501 gtaccaatcg tttgatattc ttctaaagca tgttccagca tttcttcttc acggtagtaa
    19561 tagcggtggt agccacaagg gatcatgttc atttgtttta attgttcttt gaaaaacggg
    19621 atatcaaaga tatttttcgg caatccattg tcttcatcgt ataaacgatc aatcaattct
    19681 gccgtgcggt catttccttt attatctgct actttgtgcc aatggaagtg atttagaccg
    19741 gcaaacttgt agatcagctc ttcttttttc ttgccaagca ttgttggttc tgtcatcatc
    19801 gccattactg gcacattgca taatcctatc actttatccc atttgccata tctgataact
    19861 gcttctgtca ccatcccgct tgggttcgcg aaattgatca gccaagcatt tggacataaa
    19921 cgcttcatgt cttcaacgat tgccaaaacc actggaacgg tacgaaaagc tttgaatatc
    19981 ccgccagcac catttgtttc ttgcccaatc atcccataat aactagggat ccgctcgtct
    20041 ttgattcgtg catctaattg accgacacga aactgagtcg taacaaaatc cgcatctttc
    20101 aatgcttctt cccgatccag agttgcatag attttgactt catacggaga agcatcccac
    20161 atacgctgag acatctgact gacgatctca agcttttctt ttccttcttc tacatctacg
    20221 agccagattt ctcgtatcgg taattcctca tatcttttga taaatccttc catcaactcg
    20281 ggggtgtaac tgctgcctcc accaatcgta gcgattttga ttccttttgc catgttctca
    20341 ctcctttact ttttacactt ttattatctt ttttgtaaac aaaacaaaca atagaaattc
    20401 gtttctttcc agtaacattt acaaaagtta gtgttttcta ctggattttt gtaaatatct
    20461 tgtcaaaaaa tgtctttatt aagctatata acataaatcc gtttacaaat cattttcaaa
    20521 aaagttataa tttacgtaaa aaaacaagaa gaaggtatct acatgttatt acgtgaaaaa
    20581 atcaaagaaa tctccttttc tccttcagaa aatgaagtga ttcagtttct cttaagcgat
    20641 tctccagcac ttggcgaaat gaccatccaa gagattgctg agcgatgtta tgtccacccg
    20701 tccacactca tccgtgtagc aaaaaaaatg ggttttgatg gctgggtcag ttttcgtaat
    20761 gcttttttag ctgaaacagc ctatcttgaa gggaattttc aagacgtaga tgcgaatctt
    20821 cctttttcca ccacagacgg tattatgacg atcgcaaata aaatggcttc tttagaacag
    20881 atgacgattc aagatacact ttctctcatt catcatgacc aactgcaaaa agccaaacaa
    20941 ctaatgcttc aagcaaaaaa aatcgtgatt ttcgccagta actcgaatac tttgatttct
    21001 caagatttca tgctgaaaat gaagcgcatc aaaatggatg tcacgattgt caccactttt
    21061 ggtgaatcgt tctatgaagc gtacaattgc acgagtgata tgtgcgggat tctgatttct
    21121 tatacgggtg aaaacaatgt gatccttcgt accgcagaaa tattgaaaca aaatcatgtt
    21181 ccaattttag ctttgaccag tatcggtgat tcaacgctat cttcaatgag tacagccgct
    21241 ttgcgactta cgacacgcga acgactgtat tcgaaaattg gtaattttac gatcaataca
    21301 tcgatttgtt atcttctaga cgtgttatat agttgtgttt ttgcagaaaa ttatcaacag
    21361 aatttagtcc atctaatttc tgtaggacaa aaatttgata aacgccctat cagctcagcc
    21421 atcatgaaag agcctttcaa ttttgaaaat aaagaagtgg actaaaaaga ataattaagc
    21481 ctagtccatt ctttcaccta accgttcagg tcagtgcggt gataagtgca tcgtctggcc
    21541 cgaccgtctc cccttgattt tccaaaatat ccaaataatc cgtgtaattg gtgacgatca
    21601 caggtgtttc taaactgtat ccttcctctt cgattttctt tttgtcgaag cggagcaaca
    21661 gatcgccttg tttcactctt tctccttgct gcaccaagct ttcaaaatat ttcccttcca
    21721 actgaacagt atccaatccg acatgaatca gcaattccag acctgcttca gaaaccattc
    21781 cgattgcatg tttcgtcggg aacagggtca tgactgttcc gtcaaaaggg gcacgtactt
    21841 ctcctttttc agggtagatc aagattcctc gacctagtgt tccttgtgca aaagctgcat
    21901 cctttgctgc attcagtgga gcgatttgtc cttgtatcgg tgtttttaca atttctttac
    21961 ctgatctttt ctgtctatca tctgtttcac ctgcttcctc cttccaaaag aaaaaagtca
    22021 gcgcaaagga taccaccatc gcaatggcga ttccaatcaa tacattaatc acatccgtta
    22081 aatcaccatc tggtctaata tagttgggaa ttgtaaagat gcctaatcca cctggattcc
    22141 aagaagttaa attcattaat ccactatacg cgccccctaa cgcaccaccg acacaggtaa
    22201 aaataaatat ttttttacgt ggcaatgtaa acccataaat agctggctct gtaatcccca
    22261 caataccaga aacaatggct ggtattgcga ttgctttgtc ttttgggttt ctaagcttaa
    22321 agtagagtgc agtaagtgct gcagtttgtc caaaagacac tactgcaaca ggtgtcatga
    22381 tattttgcca accattcaca gaaaattgca tcaatcccat tggtacgatt gcccaatgga
    22441 gaccaaacat cactagaatt tgccagaaga agcctacgat tgctccataa ataactggcg
    22501 aaagtgctaa aagtgtttca aatccagcca ttaaaatatc agttgcgaat gtgaatgctg
    22561 gtccaacgag taaaaaacct aagggcattg taataagaac ggtgaagaat ggaacgaaga
    22621 aattcgcgat catctcaggt actaactttt taattggttt ctgaatttgg ctagctaaca
    22681 acacaataaa gataatggga atgacagaag aagcgtagtt acgcgcaatc cagggaatgc
    22741 cgaatactgt ttgataaata ggtgcttcaa aaatagtgcc agaaaatatg gtagtcagtg
    22801 gtgcttctgc tgcaccactc aaagcttcca gcgacaagct aggattcatt aatgctgccc
    22861 caagcaacat ccctacgaat tcatttactt taaatttacg ggcagctgtt aaaccgataa
    22921 taacaggcat aaattggaat acagaatcac cgatattatc aaacataaca aatgtgccag
    22981 aaccgcggtc aaatgcgcct aagaagacaa gtaatgctgt cagtccacga atcatcccac
    23041 cagcagctag aatagcaagg aatggctgga aacagcccga tattccatca ataagcatat
    23101 caaacggtct cattttttct gttgaaacag cctcatcaaa agtaaggttt cctgctttta
    23161 taacctcttc aaacacgact ggcacatgat tcccgatgac aacttggtac tgtcctcccg
    23221 ctcgcattac cgtcacaaca ccgtccatat ttttcaagat ctcatcattt gctttttctt
    23281 cgttttttaa tttgaaacga agccttgtga tacaatgtgt caaaccattg atattttcct
    23341 tcccgccgac attttctaca attttgctcg ctaattcttg atattttccc atttctattc
    23401 cctccaattt attagtggaa ggtttagcca actgaatgtc actaccctta tttcatgcgt
    23461 tcttgttaat ttatcctcct ttttttattt atttacaacg attctcatgc actaaacgcg
    23521 caatatggat cgttaaatac attttttcgt ccgtggacat ctggtagttg aatatctcgg
    23581 ctaaaaagtc tgctattttc tcaacgcaac caaacgtatc cttatatttt ttttgaataa
    23641 cctggtacaa ttcctcagaa acttctccca cttctgattt ttctccatct aggacgcgtg
    23701 tcagaaaaaa acgtaggtgt gtgacgaatc gaaaaaaatg gactgaatct tcatcaaatg
    23761 taatcttata gtaatagcgg acgatattta gaatatcctg tattgttgta gtaaacaggt
    23821 aggtattgtc ttgttggctt tgaatgcctt gtgcattgac taaatgcaat gcgataaatc
    23881 cggcttcatc ttctgataac ttgatgtggt atttatccga gattttcttc actgtttttt
    23941 tcccgatggc atactcttta ggaaatagtt gtttgatatc atacagcaat acatttggta
    24001 caaatattcc cattttgtga cgttcgatag ccgtatacaa atgatccgtc aatgcaatat
    24061 acaccgaatc attcaactgg acttgtagag cctcttttgt atattcaatg atttcacaag
    24121 aaatttctaa gtactcaaga ggaatcgctt gtgccaattc ttggaactgt tgtgaaagtc
    24181 cgtcatttgt caactgaaat tttttgtcga tgcatgagtc aaaaatcggg tcacccactt
    24241 tctttttgaa tgccaaacct tttcccatca cgatcatttc ctgatttctt tcatccctgg
    24301 ttattacgac gttgttattc agtactttct caatcagcat gttttactcc tttccatgat
    24361 atatagggct gtatccaaaa caaaaagaaa aacccaaaaa gccgtccatg gaaccatggg
    24421 agactcatca ggtttagctt gcatcaggca atcactatcc aagttgtatc gttttcttta
    24481 tattatcgaa agcaagcact tttgtcaacg ctttcttagc ggctattggg cacttctgac
    24541 tagctgtcgt gatttttttt aaatctggta attacgacac taacgctcac agatgaagaa
    24601 tctgggaagc tctgttttat tttcactcta gcgcttaggt caaaatgcta ctatgctact
    24661 gtcccaactt ctaatatacg gtgttccagt accagcttat cggtgataag ccaaatttat
    24721 gcaaaaatct ggaaagcctt ttttacaatt tttttcttat cacctaaagc tgaacggagc
    24781 cctgtcacaa ccacttttta cacaccactg ctttgcagtt tgtacatatc tgcatacaaa
    24841 ccattttgcg ctagaagtgt ttcatgattc ccacgttcta ctatatgacc tttgtctaaa
    24901 actaaaatca attctgcatc ccgaatcgtg gacagccgat gggcaatcgc aatcgttgtc
    24961 cgtccttgtc gcatttttgt caatccttct tggatcaatc cttctgtttc agtatcgata
    25021 tttgctgtcg cttcatccaa tactagtatt ttaggatctg tcacgattgt tcgcgcaaaa
    25081 gtgatcagct gtcgttgtcc gctagaatag ctggcaccgt gttcgatcac ttttgagtga
    25141 tatccttttg gtaattcatc gatgaacttg tttgcttgaa caaactcagc tgcatggcga
    25201 atctgttcgt ctgtgatagt tggattcatc atccggatat ttcctgcgat atctccataa
    25261 aacaagaagg catcttgcaa gaccaatccc attttcttac gtaactcttc cattggatat
    25321 tctcgaatgt catgatcatc aatcaagatc tggccttcat aaaattcgta aaaccgcatc
    25381 aatacgttga tgatcgagct ttttccgctt ccggtgtgcc ccactaatgc aacggtctct
    25441 cccggattag cgacaaaaga gatattgttc aatacattgt gctctccatc ataagaaaag
    25501 cttacattgc gaaactcgat cttacctgaa gtaatcgctt gatctgctcc aggattttgt
    25561 tgcggtgcat attcttctgt atccatgatt ttcaaaatac gactaccggc aaccattcca
    25621 tctgtaaagg tgctcaaaaa gtccatcatt tgagacattg gattaaaaaa tccctggaca
    25681 taggtcgtaa atgcatagat cagtccaact tctacgggag aatgcagcgc atcgatccca
    25741 aacaaagtca acgccaacgc aatcgccaat gcatatagaa aattgatgat cggacttaac
    25801 agaatcgaat ttgttttgat catcgcatag cgcgtgtcta aatactcgtt gttcacttgt
    25861 tcaaattctt tagctaaacg agcttcttgg cgaaactgct ggataatacg catgccggaa
    25921 atcgattcat tcaatttcgt gttcagctga cttaattttt cccgcatatt ccggtaaata
    25981 cgagaactga atttctggta ataccagatg acgattccta aaatcggcaa gaacaccaaa
    26041 gtccacaagg caatttctcc attgatttga aacatggcaa tgaaggaaga aacgactgca
    26101 aagatcccag tcaataccat caaaaagaca taccaaaatt caaatagcgt ttctgtgtca
    26161 tttgtcactc gagaaacagt cgatcctgcc ggtgtctgat caaaataacg catacctagt
    26221 gtatgcagct tttcaaataa tcttacccga acatactgat aggtcttcaa tgaagccatg
    26281 gaatacaaat accattggaa aaaccaaatg atacttttga ctatgactcc aaacaagtac
    26341 ataccagcaa aaaacaaaat aacttgtgtc gtagccgact gtttagccag atgatcatcc
    26401 ataaaagttt ggatgatcct tggcaatagg acattgatca cagacagggc aaacgcaaat
    26461 aagatagcaa cgatgaacgt tcttctaaaa ggtttggcga acttcatcag tcgtttgatg
    26521 atcttcttct gttctttaag tggaatcgat tttgtccatt ccgattgata attttcatcc
    26581 atcaggcctc gcctccttct atcttcgctt ctaatttctg tttctcccac attcgttcat
    26641 accagccgcc taatgcaagc agctcatgat gggttcctcg ttcaatgatt ttcccttgat
    26701 cgacaacaat gatttctttt gcatgcatca cgctgcttaa acggtgagct gcaatgatgg
    26761 ttgttttctc ttttcttatt tcttttaaat tatgcaagat agcttcttct gttttggcat
    26821 ctactgcaga aagtgcatca tctaagatca gcaattcagg atttttgatc aatgctcgag
    26881 caatcgaaat cctttgtttc tgtccgccag ataaagagac tccacgttct ccaactaagg
    26941 tatcataacc ttttggtaat tccttgattt cattgttgat aaatgctaaa gaagccgcat
    27001 gctctacttc ttcttctgaa agttttggat tagaaaaacg gatattatct cgaatggtca
    27061 tcgaaaacaa gaagtgatct tgaggcacat agccgattga tcctaataaa gcattcaatg
    27121 aatattcttt gatcgaacat ccgccaaatt gaatttttcc ttgataatca tcgtattcac
    27181 gcatcagtaa tttgatgatt gtcgtttttc ccgcaccagt tttcccaaca atacctaatg
    27241 tttctccttc ttggatcgca aatttgattt gttctaatgc tggtgattct tctttcggat
    27301 agttaaaaga ggaaatagct acattcagct cgccttttgc cggagtctgc actgcaccca
    27361 gttgttccac gatatgcgtc ttttcatgca aaagttcatt gacgcgatca taagaagcat
    27421 ttcctctttc caatacgttg aacaatcgac caatcgcaaa catcggccaa acaagcatac
    27481 cgatatagct aataaatgag accatctgcc cgattgagat cgtgccttcc aagacatact
    27541 ttccacctaa aataattgtt gcaacataag acagaccgat aatcaaggta atgaatggat
    27601 caaataagga gtctaaaaaa ttgactcgtt tgtttttaat aattgcatct tcaatctttt
    27661 cttcaaaatc cgcgagatct tctttttctt gtccaaatgt tttaatgact ttgatcccag
    27721 taatactttc ttgtgtctta tcattgatac tagaaaaagc ttcttgcgaa tcacgaaaag
    27781 catcgtggag ttttgacccc agcactcgtg aagtaacggc tagtaaaggc agaggaatca
    27841 gcgcaatcag tgttaagcgc caatcaataa acaaaatcat cgcaatgatc gttgttccgc
    27901 ccgtgatcac tgaatctgca aaggtcaaga taccagctcc tgctacattt tggattgcat
    27961 tcaaatcatt cgttgcatga gccatcaaat ctccagtccg atatttttgg taaaagagat
    28021 tgtccatttc tgtaaaatgt ttgaatagct gctgccgaag ttctttctcc aaccgagctg
    28081 cacttcccca aatattcgtc cgccagatat aacgaaaaag atattgtaag agagctgcaa
    28141 ggatcaataa taagatccac caggaaatga tctttattga taaattttta tcggcgatct
    28201 catcaatgat gatcccaatc acttttggag gagctaactg taccaaggcc actgcgaata
    28261 gggagaaaat cccaattaaa taatgtttct tttcctgtcg aaaaaaccaa cctaattttc
    28321 taaaaatcga cattttactc ctcctttgtc tttatcaaga gcataggatt gtctgtgctt
    28381 gtcttttttg ctgaatagtc tgaatagtct aacaaattac gaaataaaaa acggactgaa
    28441 aaaatcagcc cgcaaaaagt ctttgggtca gaacctattt tttcccttgg ttcttcattt
    28501 gctgcatcat ctggcgaatt ttcttctcag atggtttttg ccccattgac atcatcattg
    28561 atcgcaacat gtcctcatta acgggaggat ttttttctaa atagtctttc atatatttac
    28621 gcgctaggaa aaagccacct actgcgccga ttagcaaagc aataatagca ataagtacga
    28681 caatacctgt tgataccata taaatctctc ctttctattt ccgaattgct ctcaatgatt
    28741 tattttacta aagtttattg aaaaaagaaa ggcgtattct ttagtttcat gcaaaaaata
    28801 gtggtttttt tagagaagaa caaaatttct ttcattaacc agcaagacac gccacgaaaa
    28861 aaaattaggc ataccaaatc tttttcttta attttttctt tctgaggtgt agaatgtaat
    28921 cgtagataaa taggaaaggt ggttttttct tgaataatca atccaacaaa caatttcata
    28981 agcatcgact tattgaacat acaaatggtt tatctttagc tgaagtaaat ggaacagtgg
    29041 atgtacccaa gggaaaaagt ttttttaaaa cacttcttgc ttactctgga ccaggtgcat
    29101 tagtagcagt tggttatatg gatccaggta actggtccac ttcgatcact ggtggacaaa
    29161 atttccaata tttattgatg tcagttattt tgatgtctag tctgattgct atgcttttac
    29221 aatatatggc agcaaaatta ggaatcgtga cccaaatgga tttggcccaa gcaatccgag
    29281 cacggacaag taagacattg ggtgtcattt tatggatctt gactgaatta gccattatgg
    29341 caacagacat cgcagaagtc attggtgcag caatcgccct ctacctgctt tttgatattc
    29401 cattggtaat tgccgtattt atcactgtgt tagatgtttt cgtcctttta ttgctgacaa
    29461 aagtcgggtt tcgtaaaatc gaagctttgg ttgtctgctt gattttcgtc attttattcg
    29521 ttttcgtcta tcaagttggc ttgtctaacc ctgattggca cagtttgttt gccggattta
    29581 tccctaacag tcacacattc tcagactcac cggtcatcgg cggcgaaact ccgctgactg
    29641 gagctttagg gattattggt gcaacagtca tgccgcataa cttatatctt cattcagcag
    29701 tttctcaaac tcggaagatc gatcaccaag acgaagaaga tgtagcacaa gcggtacgct
    29761 tttctacttg ggattctaat atccagttgt caatggcttt tctagtcaat gcactgctat
    29821 tgatcatggg tgtggctgta ttcaaaaccg gttctgtcca agatccttcc ttttttggtc
    29881 tgtatgaagc tttatctgat ccatcagcta tgagcaatgg tatcttgatt gctgtagcaa
    29941 aatctggtat cttgtctact ttatttgctg tagcacttct tgcttctggc cagaactcta
    30001 ctattactgg tacgttgacc ggtcaagtca tcatggaagg cttcatccat atgcgtatcc
    30061 caatttggct aagaagacta gtcacacgat tgctttctgt gattcctgta ttgatttgtg
    30121 ttttgtttac aagtacaaaa ggaacgatcg aagaacatac cgctttgaat aacttgatga
    30181 atgaatccca agtttttctg gcttttgcat tgccattctc gatgattcct ttactgatga
    30241 tgaccaatag ccaagcggag atggggagcc gattcaaaaa ttcatttgtt gtaaaactac
    30301 ttggctggtt ctctgtgatt agtctgactt acttgaattt acgaggatta ccaggtcaaa
    30361 tcgaaagttt cttcggcgag caagccacct cagctcaact agcattggct gatcaaatcg
    30421 cttatgtaat cattgttctt gtccttctcc tgttggcatg gacgattggt gatttatata
    30481 aaggaaacaa aaaatatgaa cagcgtttgc aggaaacgat agaagaaatc gagtagaaac
    30541 tgattctttt acacaaagga ggttgtgtca gaagtgggca gcttcaagaa ataagaagga
    30601 atttaagaaa attgcttttc aaatttttgt gaaatttcgg cttatttccg aagaagttac
    30661 ttctggaaca ccgtgtatca gaggttgtga aaaagctgcc ttgcatcaag taataagaac
    30721 agccaagtaa aaacagcttt ttatgttttt aacttggttg gacttattac cgcagatgca
    30781 agcttttgag caccgtttat tcggaaaaag gaactgcgac aagacttttg tcacagttcc
    30841 ctttcctacg attagtcaag taaaaggtgt aagaaaaata gctcataaac gaaagcgaca
    30901 aaatcaa
//
LOCUS       DAMEEU010000029        30017 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.030, whole genome shotgun sequence.
ACCESSION   DAMEEU010000029 DAMEEU010000000
VERSION     DAMEEU010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 30017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.030"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(61..2424)
                     /locus_tag="PB779_001311"
     CDS             complement(61..2424)
                     /locus_tag="PB779_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
                     /protein_id="HDE0738844.1"
                     /translation="MDYSSKEYFDKMTAWWRAANYLSVGQLYLKDNPLLRRTLKPEDV
                     KKHPIGHWGTIPGQNFIYVHLNRVINKYDLNMFYIEGPGHGGQVMVSNAYLDGSYTEI
                     YPEVTEDETGMQKLFKRFSFPGGIASHAAPETPGSIHEGGELGYSLSHAVGAVLDNPE
                     VISAVVIGDGEAETGPLAGSWFSNVFINPVIDGAVLPILHLNGAKIANPTILARKSDG
                     ELANYFNGLGWEPFFIEGNDPEKLNPVMAEKMDQAIEKIKSIQKEARLKTATDVVMPK
                     WPVLIVRTPKGWTGPKEWDGEPIEGTFRAHQVPIPVDQEHMDHADALLRWLKSYEPEK
                     LFDAQGRILEEIREIAPTGDQRMAKNPITNGGIDPRPLIMPDWKKYTLQFEKPGSVKA
                     EDMTELGKFVREIIEKNPENFRIFGPDETKSNRLNQVFKTTNRQWMEKIEPENDEWLS
                     PSGRVIDSQLSEHQDEGFLEGYVLTGRHGFFASYESFLRVVDSMLTQHFKWIRKSHDL
                     SWRKDYPSLNLIASSTVFQQDHNGYSHQDPGILTHLAEKKAEFIREYLPADANTLLAV
                     MDKAFRSSEKINLIISSKHPRAQFYSAEEAAVLVNEGLKIIDWASTAKEEEPELVIAA
                     AGTESNLEALAAVTLLLEEFPKLKIRFINVVDLLKLRHPSQDPRGLSDEEFDQYFTKD
                     KPILFAFHGYETLVRTIFFDRHNHHLMIHGYKENGDITTPFDMRVVNELDRYHLAKDA
                     ALKIKGSQAEDFAEKMDQKLQEHQNYIRENGIDLPEVLDWKWKNLDQ"
     gene            2872..3093
                     /locus_tag="PB779_001312"
     CDS             2872..3093
                     /locus_tag="PB779_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738845.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYYRKKKVEFFTFLFLFFG"
     gene            complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="PB779_001313"
     CDS             complement(3201..3548)
                     /gene="rbfA"
                     /locus_tag="PB779_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HDE0738846.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKKAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
     gene            complement(3575..5881)
                     /gene="infB"
                     /locus_tag="PB779_001314"
     CDS             complement(3575..5881)
                     /gene="infB"
                     /locus_tag="PB779_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HDE0738847.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSSDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            complement(5894..6205)
                     /locus_tag="PB779_001315"
     CDS             complement(5894..6205)
                     /locus_tag="PB779_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HDE0738848.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            complement(6202..6495)
                     /locus_tag="PB779_001316"
     CDS             complement(6202..6495)
                     /locus_tag="PB779_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HDE0738849.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="PB779_001317"
     CDS             complement(6517..7692)
                     /gene="nusA"
                     /locus_tag="PB779_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HDE0738850.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="PB779_001318"
     CDS             complement(7716..8189)
                     /gene="rimP"
                     /locus_tag="PB779_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HDE0738851.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            complement(8333..12685)
                     /locus_tag="PB779_001319"
     CDS             complement(8333..12685)
                     /locus_tag="PB779_001319"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HDE0738852.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIQ
                     LGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSFIV
                     KKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYAPE
                     GEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGKKA
                     GVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAVKM
                     YKGNVIESFDEFIDPGHPLSRTTVDLTGITDEMVRGSKSEEEVLRMFLEFSKDTILVA
                     HNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSLEQ
                     HHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILAKN
                     QAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKGVE
                     EARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVATGN
                     VHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEIVV
                     ENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRLEK
                     ELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAPHY
                     YCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPDID
                     LNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSAEV
                     DRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHSIH
                     DNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIYSK
                     TGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDATLA
                     EVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVPDW
                     YIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMCKG
                     KDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFVIE
                     GDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGVLK
                     DLPDENQLSLFDML"
     gene            complement(12897..14606)
                     /locus_tag="PB779_001320"
     CDS             complement(12897..14606)
                     /locus_tag="PB779_001320"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HDE0738853.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPKRDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="PB779_001321"
     CDS             complement(14674..15942)
                     /gene="rseP"
                     /locus_tag="PB779_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HDE0738854.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            complement(16103..16903)
                     /locus_tag="PB779_001322"
     CDS             complement(16103..16903)
                     /locus_tag="PB779_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HDE0738855.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSTVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            complement(16900..17712)
                     /locus_tag="PB779_001323"
     CDS             complement(16900..17712)
                     /locus_tag="PB779_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HDE0738856.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            complement(17907..18464)
                     /gene="frr"
                     /locus_tag="PB779_001324"
     CDS             complement(17907..18464)
                     /gene="frr"
                     /locus_tag="PB779_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HDE0738857.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(18467..19189)
                     /locus_tag="PB779_001325"
     CDS             complement(18467..19189)
                     /locus_tag="PB779_001325"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HDE0738858.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(19325..20206)
                     /locus_tag="PB779_001326"
     CDS             complement(19325..20206)
                     /locus_tag="PB779_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HDE0738859.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="PB779_001327"
     CDS             complement(20305..21087)
                     /gene="rpsB"
                     /locus_tag="PB779_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HDE0738860.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            21446..21925
                     /locus_tag="PB779_001328"
     CDS             21446..21925
                     /locus_tag="PB779_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HDE0738861.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            22142..23233
                     /gene="phnW"
                     /locus_tag="PB779_001329"
     CDS             22142..23233
                     /gene="phnW"
                     /locus_tag="PB779_001329"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HDE0738862.1"
                     /translation="MYKLLTPGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSGSFGVESVLSSVIRPEDTVLICSNGAYGQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQEKDLL
                     FIVDAMSSFGGIPIRVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            23226..24011
                     /locus_tag="PB779_001330"
     CDS             23226..24011
                     /locus_tag="PB779_001330"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HDE0738863.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGIQLTDKEIREP
                     MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEHYLFKDLVKHSTLKP
                     DTLETIERLRNAGINIGSTTGFTAPMMTIVAETAKKEGYSPDFMATSEDVEGYGRPFP
                     YMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEGSSLMGISYDEYQKL
                     EMGKKDRLKQSVALRFQQAGADICVNNLKELTEYILYADKNPE"
     gene            complement(24357..26048)
                     /locus_tag="PB779_001331"
     CDS             complement(24357..26048)
                     /locus_tag="PB779_001331"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HDE0738864.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDEEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMRHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
     gene            complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="PB779_001332"
     CDS             complement(26470..27417)
                     /gene="arcC"
                     /locus_tag="PB779_001332"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HDE0738865.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(27532..28551)
                     /gene="argF"
                     /locus_tag="PB779_001333"
     CDS             complement(27532..28551)
                     /gene="argF"
                     /locus_tag="PB779_001333"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HDE0738866.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="PB779_001334"
     CDS             complement(28642..29871)
                     /gene="arcA"
                     /locus_tag="PB779_001334"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HDE0738867.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
BASE COUNT         8006 a         6456 c         5350 g        10205 t
ORIGIN      
        1 cttaatttga caaataatac aatgtaaaaa attctgtttt gcgggatcga ttttatcatt
       61 ttattggtca agatttttcc atttccaatc caatacttct ggcagatcaa taccattttc
      121 acgaatatag ttttgatgtt cttgtaattt ctgatccatt ttttccgcaa aatcttctgc
      181 ttgacttcct ttgattttta aagctgcgtc ttttgccaaa tgataacgat caagttcatt
      241 tactacacgc atgtcaaatg gtgtcgtgat atctccattt tctttgtagc catgaatcat
      301 taaatgatgg ttatgacgat caaagaaaat cgtgcggacc aatgtttcat aaccgtggaa
      361 agcaaataag atcggtttgt cttttgtaaa atattgatca aattcttcat cgctcaaccc
      421 acgcggatct tgacttggat gacgtaattt caataaatct acgacattga tgaaccgaat
      481 ttttagtttt gggaattctt ccagcagcaa agttacagct gctaatgctt ctaagttaga
      541 ttccgttcct gcagcagcaa tgaccaattc aggttcctcc tcttttgctg tcgaagccca
      601 atcaatgatt ttcaagcctt cattcactaa gacggctgct tcttctgctg agtaaaattg
      661 agcacgcgga tgtttggaag agatgatcaa attgattttt tctgacgagc ggaatgcttt
      721 atccatgact gcgagcaatg tatttgcatc cgcaggcaga tattcacgga tgaactccgc
      781 cttcttttct gccaaatgtg tcaatattcc tggatcttgg tggctatatc cattgtgatc
      841 ttgctggaag actgttgagc ttgcaatgag attcagcgaa ggataatctt ttcgccaaga
      901 aaggtcatgt gatttccgta tccatttgaa gtgctgagtc aacatagagt caaccactcg
      961 caagaatgat tcgtaacttg caaaaaaacc atgccgtcca gtcagaacgt acccttctaa
     1021 gaacccttca tcttggtgtt ccgataattg actgtcgatg acgcgaccag atggcgaaag
     1081 ccattcatca ttttctggtt cgattttttc catccattgg cgatttgtcg ttttgaaaac
     1141 ttgattcaat cggtttgatt ttgtttcatc tggtccaaat atacggaaat tttctggatt
     1201 tttctcaatg atctcgcgaa cgaatttacc aagttcggtc atatcttctg ctttaacgga
     1261 gcctggtttt tcaaattgca aagtatattt tttccaatct ggcataataa gcggtcttgg
     1321 atcgattcca ccattggtga taggattttt tgccattctt tggtcaccag taggcgcaat
     1381 ttctctgatt tcttctaaaa tacgtccttg tgcatcaaat aatttttctg gttcatagga
     1441 tttcagccaa cggagtaaag catctgcatg atccatatgt tcttgatcta caggaatcgg
     1501 tacttggtgt gctcggaagg ttccttcaat tggttccccg tcccattctt ttggaccggt
     1561 ccatcctttt ggtgtgcgta cgatcaatac tggccatttt ggcatcacga catctgttgc
     1621 tgtcttcagg cgagcttctt tttggatgga tttgattttc tcgattgctt gatccatttt
     1681 ttcagccata acaggattta atttttctgg atcatttcct tcaataaaga aaggctccca
     1741 gccaagtccg ttaaagtaat ttgctaattc tccatctgat ttacgtgcca agatcgttgg
     1801 gttggctatt tttgcaccat ttaaatgaag gatcggtaaa acagctccat ctatcactgg
     1861 attgataaag acatttgaga accagcttcc agctaaagga ccggtttctg cttcaccatc
     1921 accaatcacg acagcagaga ttacttcagg attgtctaat acagctccga ctgcatgtga
     1981 aagagagtat ccaagctctc cgccttcatg gatagaacct ggtgtttctg gtgctgcatg
     2041 agaagcaatg cctccaggaa atgaaaatcg cttgaataat ttttgcattc ctgtctcatc
     2101 ttccgttact tctggataga tctctgtgta acttccatct aaataagcat tcgataccat
     2161 gacttgtccg ccgtgtcctg gcccttcgat ataaaacatg ttcaaatcat atttattgat
     2221 gactcggttc aaatggacat aaataaaatt ttggccagga atcgttcccc aatgaccgat
     2281 tggatgtttt ttgacatctt ctggtttcag tgtacgtctc agtaaggggt tatctttaag
     2341 ataaagttgc ccaacagaaa gataattagc agcacgccac caagccgtca ttttatcaaa
     2401 gtattcttta ctagaataat ccatacataa cactcctttt cattattact cttattctag
     2461 cgcagatact cccaattgaa acctaataag cacttctgtt catttgtttg gattttatat
     2521 ctagccaaat gaacaggtat aaaaaaccac gaaatttttc ctttcgctga cgttttttac
     2581 attgatccaa aaaacttgtc gttatcacaa tggctgttcc gcagttcatt tcgctcctca
     2641 tcatgcataa tttgctgaat gacgctaggc cagttaacac attgttggaa aactggggct
     2701 ggatcgagca attcctttcc tgattgatcc gttttatgta aaagtctctg ttatctttgt
     2761 caatatgtga attggtatcc cagctactat gctaatttct acagggatta tccaaaattt
     2821 ggatcgtgac caaatcgaag cggcgtaatc ggaaatatca ataacttcaa cgtgattttt
     2881 cttttaactg tcaacggacc gacaaactca aacttttatg gtgcaggttc cactgatctt
     2941 ctagttactt ggctatacct gactgtcact aaaatagatt acaatctagc ttccgttatc
     3001 ggtatcttga tctttatcta tatgcaaaaa tttatatact atagaaaaaa gaaagtcgaa
     3061 ttttttactt ttctttttct cttttttggt tagctgacac gctaccagac taaagtcatg
     3121 gaactcttag gtaatacgtc ttaatgaaaa caaaaaaatc ccgcaacccc tgatttcaca
     3181 ggatttgcgg gattttttga ttagtctttg ttcaagtcgc gaagcaattc atcgatatgg
     3241 ttcccataga caactgattc atcaagttca aagaacaatt caggtgtctt ataaatactt
     3301 agattgtgcc ctaactctcg acgaatcaat cctgatgctt tattcaatcc atcttgtgct
     3361 tttttcttat ctgatgctaa gtcagataaa atgctgtaat agatcgttgc ttgctgtaag
     3421 tcccccgtaa ctttcacatc tgtgatcgtt acgttctcca cacgagggtc acggaccttt
     3481 ttgcgcaaaa tatcattgac ttcttttaag atttcttgac cgactcggcg atcacggtag
     3541 ttagccataa tgattggcct ccttttatca gtttttagtc atttttgact tcttccatga
     3601 taaatccttc aattacgtca tctactttga tgtcattgaa tttttcaatc atcgcaccac
     3661 attcataacc cattttgact tctttcacgt catctttgaa tcgtttcaga cttgcaagtt
     3721 ggccttcata gattacgatt ccgtcacgga ttacacggac accgctatct ctacgaatat
     3781 atccttctgt tacataggca cctgcaatcg taccaacttt agaaactttg aaggtttcac
     3841 gaacgatcat ttgaccggtg attttttctt caaattcagg gtctagcatc cctttcatcg
     3901 cagtttcgat ttcttcgatg gctttataga tgatacggtg aagacgaata tcgacttctt
     3961 cagtatcagc ttgcactttt gcctgcggtg taggacgaac gttgaaaccg atgataatag
     4021 cgttgctggc tgctgctaag gttacatcac tttcattgat tgctccgaca gctgaatgga
     4081 cgatttttac acggacacct tccacatcaa tcttcttcaa tgatgcagcc agtgcttctg
     4141 ctgaaccttg tacatctgct ttgatgatta cgttaacttc tttcaattcg ccttctttca
     4201 ggctttcaaa taagttgtcc aaagtcacac ggcttgtggc agcacggttt tccaataatg
     4261 cacgttttgc gcgttcttca cccgctgcac gtgctgtctt ttcgtcttcg aagactacga
     4321 aacggtcacc tgcttgaggt acatcattca agccagtgat ttctactggc gttgcaggtc
     4381 ctgcttcttt atcgcgacgg ccaagatcgt ttgtcattac acggacacgt ccgtaagtat
     4441 taccgacaac gattgggtca ccaacgtgaa gtgttccttc ttggacaagt aaggttgaca
     4501 caggaccttt acctttatca agacgtgctt cgatcactgt tccgattgcg cgttgtgttg
     4561 gatctgcttt taaatcttct acttctgcga ctaacaggat catttccagc aattcttcga
     4621 tgttttggcc gaatttcgct gagatctcaa caaaaatcgt ttctccaccc catgcttcag
     4681 gaattaattc atactcactt aattcttgca taacatgctg aggatttgca cctggtttat
     4741 caattttatt tacagcgacg atgattggaa cgcctgcagc tttggcatgg ttgattgctt
     4801 caactgtttg tggcatgacg ccatcatctg cagcaacaac taagatcgtg atatctgtga
     4861 tacttgctcc acgtgcacgc atacttgtaa aggccgcatg tcctggtgta tccaagaaag
     4921 tgattggttt accatcaata tcgatctggt aggcaccgat atgctgtgtg attccgccgg
     4981 cttcgccgct tgttacacgt gaatggcgca atgtatccaa taaggttgtt ttcccgtggt
     5041 ctacgtgtcc cataatcgtt actactggcg gacgtgagac taatttatct ggatcgactt
     5101 cttctgcctc gaagaattta tcgatatcag caatgtcaac ttggactttt tcttgtggtt
     5161 ccatgccata gtccgtcgct aacagttcaa tcgtatcttt atccagtgct tggttttgat
     5221 tgaccatgac accaagcata aataattttt taatgatttc tgctggctca cgatgaattt
     5281 ttttcgcaat atctgctacg ttcatacctt cagtatactc taatacatct ggcaattcac
     5341 ggaatttgcg tggtggtaca gctggtttag ttgattgttg ctgtttgcct tttttacctt
     5401 ttttattata acgattacgg ttattattat taaatttgcc gcgattgtta ttgtttggtt
     5461 tgttgttatt gttagtacgg ttttgattgc cgccttggct cgttccttga cgattttggc
     5521 tgctggtatt tcccgtatta ttttggtttg ttgttggttt ttttccttga ttcacttgac
     5581 cgctcccttg accgcgatct tgataactgc ggttattttt atttttttgt tgattgttcg
     5641 ttgtttcttt tttacgttga tcgttcggct gttgattggc tggttttctg cttgcttgtt
     5701 gtgcagcttg ttgtttcgtg cttgggtttt tgaacgcttg ttgcaatttc ttctcatcac
     5761 tgctagtaat cgcacccata tggtttttca catcgatgcc aagttgttgt gctttttcca
     5821 cgacgtcttt actagatttt ttgagttctt ttgctaattc atagattctt ttgttgccca
     5881 tgcaatcacc ttcctaacct tcaattagct ccttggtctt cttcgcaaat ccggcatcca
     5941 ttattccgaa taccttgcga ggttttccga tcatctgcgt gatttctgct tcagaaaata
     6001 gctcaaagca aggaacttca taatatgaac tcttatcttt tatctttttt cttgtattct
     6061 cacttgcatc ggttgccaca aacaccaatt ttgctttttg tttgcggatt tcagcaatgg
     6121 tcagttcttc acccgtgatt agttttcccg cgcgcatcgc tagaccgatg agattcatgg
     6181 ctttttgccg attaactgta ttcattttcc aaataactct ttacgtgctt tttggtgagt
     6241 gacatagtca agaagttctt gataaaactc atctgttaat gttgtttcga gtactcgatc
     6301 gagaattttt ttatcccaag cttgttgtac ttcttccggc tcaagtgaga catacgctcc
     6361 tcgtccaggc atttttccag ttggatcgat cgatacttcc ccttcttttg aacgggtgat
     6421 tcggaccatc tcttttttag gtttcatttc acctgaaacc acggatttgc gtaaaggaat
     6481 tttcctttgt ttcatctctt tgcctcctta ctaaagttaa gcttctggtt tttcttcgac
     6541 cgtttcattg ttgaatgcaa ttgtttcata ttcatcgtct gttaaatctg actgaacgat
     6601 tgcttcatca tgcagttctt ctgtttcttt ttgttgttct tgattttcat aaaattccgt
     6661 catgtcagat tctgatttga tatcgatttt atggttagtc aatttagcag ctaaacgtgc
     6721 attttgtccg cgtttaccga ttgctagcga taattggtag tctggaacga caactgtgca
     6781 ggcctttgga tttgtctcat cgaagatcac atccatgact tgtgcaggat tcaatgcatt
     6841 tgcgatgaat acagctggat cttcattcca ttcgacgata tccatgtttt cgccttttaa
     6901 ttcattgacg attgcttgaa ctcgttgtcc ctttggcccg acacatgtac cgactgcatc
     6961 gatatttgga tcatttgagc gaactgccac ttttgaacga tcgccagctt cacgggcgat
     7021 gctgacaatt tcaacgattc catcatagac ttctggtact tcttgttcaa ataagcgacg
     7081 caataggtct ggatggctgc ggctaacaaa tacttgcgga cctttagacg tattttctac
     7141 tcgggaaaca taaactttga ttcgatcatg tggttgataa aattcatttg gcatttgatc
     7201 ttgtttagaa agaactgcct caattttacc aagattgaca taaatataac gtttatcctg
     7261 gcgttcgacg attccttgca tgatgtcttt ttcataagca ctgaattcgt tataaataat
     7321 cgttctttct gcttcacgta cacgctgtaa aataacttgt ttagccgttt gcgcagcgat
     7381 ccgtccaaaa tcttttggtg ttacttcaaa acggatcgta tcaccgatct catatgctgg
     7441 attgattaaa agtgcatctt tcaatgagac ttccaactgt gaatccatca cttcttccgt
     7501 tacttctttt accgcataga catggatctt tccttttttc tgatcaaatt ccacttcgac
     7561 gttttgtgct tggccatagt gacgtttgta tgcagaaacc aatgctgctt ctaaagcatc
     7621 gatcacgatt tcttttgaga tccctttttc agcttctaaa gcgtctaacg catttaacat
     7681 ttctttactc atttttttct gattcctctc cgtgattaaa attggatagc taagcgagct
     7741 tttgcaatat tttttcggtc aaaagtcaat tctttttctc gtgtttttat gcgtattttc
     7801 aatgtaagct gttcagcatc aaatgattga agaaatcctt catattgttt ttcgccatct
     7861 actggttggt ataaggagac atggacataa tcaccaagtg ccttttcata gtcgctttct
     7921 tttttcaatg gccgctctgc tcccggggag gatacctcca ggaaataagc ttgaggaatc
     7981 ggatctggat ctgctgcatc aagtttttca ctcagtttct cactgacaaa ggcgcattct
     8041 tcgatatcga taccgccttc tttgtcaata aatactcgta agaaccagct ttttccttct
     8101 tttacaaatt cgacttcgac aagttcaaaa ttttgttcat ctaaaatcgg tgtcaccatt
     8161 tctgtgactg tttcaacgac gctactcaaa agtttcgcct ccttaaaaat taagtgcgta
     8221 attccattaa aaagagtgag cgaaaaatcc gctcactcac agttagtatc attacctata
     8281 agaactatac catactctgc ttaaaattac aagcagacag gaaaacagat gcttatagca
     8341 tatcgaataa cgataattga ttttcatctg gtagatcttt caatacgcca ttgtcgttca
     8401 tatattcgat caatgttttt gaaactttac cgcgggtggc aagatcttct ttggataaaa
     8461 atggaccgtc ttttcttgct tcaacgattt gtttcgccac gttggttccc aaacttggga
     8521 cagctctaaa tggtgcgatc aacgtatcac cttcaataac aaagttaacg gcatccgatt
     8581 tatacaaatc aatcattcca aatttgaatc ctcgttccag catttcattg gctaactcca
     8641 gcactgtcag ttgattcttt tcttttacgg aagcatctaa tcccttgtcc gtgatttctt
     8701 tcattgcttg tttcacagca tcttttcctt tgcacatgga gactagatca aagtcgtctg
     8761 cacgtacaga aaagtatgca cagtaataca aaatagggaa ataaaccttg aaataagcga
     8821 cacgaagagc catcaatacg taagctgcag catgggcttt cggaaacata tatttgattt
     8881 ttgaacaaga atcgatatac cagtcgggca cattattttc tttcatcgcc gatagatagg
     8941 tttctcgcaa ttcatcaggg atcttgttcc attgtccttt acgaacagtt tccatgattt
     9001 taaatgccat cccgctatct aatccagcat ggatcaaata aaccataata tcatcacgac
     9061 agccgattac ttccgccagt gtcgcatctc ctcgtcgaat caattcttcc gcatttccta
     9121 accatacgtc tgtaccatga gatagtccgg aaatttgcag tagttctgca aaagttgtag
     9181 gatgcgtttc ttctaacatc cctcgaacaa aacgagtgcc gaattctgga atacctaatg
     9241 tccctgtttt ggaataaatt tgttcctgac ttactccaag tacttcagga ccggcaaata
     9301 tccgcatcac ttccgggtca tccgtaggga tcgtttgtgg gtcgatccct gataaatctt
     9361 gaagcatccg aataacagtt gggtcatcat gccctagaat atctaatttc aatacattat
     9421 cgtgaatcga gtggaaatca aaatgagtcg ttttccattc tgaattttga tcgtctgctg
     9481 gatattggat cggcgtaaaa tcatagacat ccatataatc gggaataacg atgatccccc
     9541 ctggatgctg gccggttgtc cgtttgactc cagtagcgcc ttttgctaat ctgtcgactt
     9601 ctgcacttcg aaactgcaga ttattgtccc tttcgtatcc ttttacatag ccatatgctg
     9661 ttttgtcggc gactgtacca atcgttccgg cacggtaaac atagtcttcg ccaaacaata
     9721 ctttcgtata gttatgggct tctgcttgat aatcacctga gaagttcaaa tcaatatcgg
     9781 gcactttgtc tccatggaat cctaaaaatg tctcaaatgg aatatcatga ccgtctttgt
     9841 ttaagcgtgc accacatttt ggacattgtt tttctggcat gtcaaatcca gaaccatacg
     9901 taccatcttc aaaaaactcg gaatattggc actctggaca ataataatga ggggctaatg
     9961 gattaacttc agtgattcct gtcatcgtcg caacaaagct agagccaaca gagccacgtg
    10021 aacctactag atagccatct tcattacttt tatgcactag tttttgggcg atcagataaa
    10081 taaccgagaa gccattacca ttaatagaat tcaactcttt ttctaatcgt ttttgaatga
    10141 tctcaggtaa cggatctccg tacatttgtt ttgcttttgt gtaactcaat tctgatattt
    10201 catcttctga acctggaatc ttcggtgtat aaagttcatc tttgactgga atcacttctt
    10261 cgcagatatc tgcgatttta ttcgtatttt ctactacgat ctctttcgct gtttcttccc
    10321 ctaaaaagtg aaatgcagtt agcatctcat cggttgttcg gaaatggaca tccggcaaac
    10381 tatgacgatt caacggattc gctccgccca tagaattgat caaaattttt cggtaaatgg
    10441 catcttcttc gttcagataa tgtacattac ctgttgcaac aacgatttta tccaaacttt
    10501 ttccgatttc taccaaattt tggataattt cttccaaatc atgttcattt tttaccaatt
    10561 cttgctcgat caaaggcgca tagaccgctt ttggcataac ttcaatataa tcatagaatt
    10621 ttgctcggtt tcttgcctct tctacccctt tttgcatcat ggcttcgaat atttctccct
    10681 tatcacaagc tgagccgatc aatagatttt cacgcatctt tttcaattgg gagcgtggta
    10741 ttcgtgggac gcgttcgaag tattcgacat tcgacattga aatcagtttg aacaaatctt
    10801 tcagtcctgc ctgatttttt gctaaaatcg ttacatggaa aggtcgagcc cttttgtaag
    10861 aatctccttc tccgatatgc tcatttagct gatcatgata aagcatgtta tgattgtcca
    10921 ttgcctcttt cacaaagatc catgctaagt gaccagttgc ttcagcatca tagattgctc
    10981 ggtgatgctg ttccaagcta acaccaaact ttttagataa cacacctaat ccgaaacgtt
    11041 tgaattgagg atacagatat ctagctaatt ccaacgtatc aatgactgga ttggccgctt
    11101 caggaatacc ataccttgcg tagctagtat tcaagaaccc catatcaaaa gccgcgttgt
    11161 gggctaccaa aattgtatct tttgaaaatt caaggaacat ccgcaatact tcttcttccg
    11221 actttgaccc tcgaaccatt tcatccgtga taccagtcag atctaccgtt gttcgtgaca
    11281 atggatgtcc tggatcgata aattcatcaa agctttcgat cacatttcct ttatacattt
    11341 tgactgcggc tagctcgatg atcgtgtcat atactgcaga caatcctgtc gtttccacgt
    11401 caaatacgac gtatgtggct tcactcaatg cttcatgtgc atcattataa gcaattggga
    11461 caccatcatc tacgacattc gcttccacgc cgtataagat tttcacacct gctttttttc
    11521 cagcactatg tgcttccgga aaggcttgcg caccaccatg gtctgtaatg gcgatagctc
    11581 ggtgtcccca ttttcctgct tgtgccacaa gatcagagat gctgtttgtt gcatccatcg
    11641 tactcatatt gctatgaaca tgaagctcta ctcgtttttc cccttcagga gcataatctt
    11701 tgcgaggtgt atgtttgact tctatgatat cttgcgcatt catgaccaaa tcacggacaa
    11761 acgtatcttc ttgaatactt cctcgtacct ttaaccagct accgacactg atcgcatcaa
    11821 atacttgttc atctttttcg ccgttcgaga attttttgac gataaatgat gaagtataat
    11881 ctgtgatttt caaagtcaag atcttgcgtt ttgaacgtag ttctctgact tctttgtcga
    11941 atacgtaccc ctcaagtgtg actcttcgtt cttcttcaac gatactgatc attggtgtcg
    12001 ttggttcatc ggctggaata tttcgtccta gctggatggg tccttcaaga gctggcgatt
    12061 gctcttttct ttcctttttc ttttgttcgt ggacaactag actttcagct gcttgcttca
    12121 taaaggcttc tgcctgttct tgtttgcgtt cttcaaaaag tttcaataca cgttccgctt
    12181 gctgctcatc cacttctggt tcgatacgaa attttgggaa tccgtaactg acgaacaact
    12241 cttctactaa tggcaagtat tgttgcttca aataagaaat agctcctgta ctgtcgattg
    12301 gcaagatgac tttacgatct tttatcacag gtacctgcgt tttcaatact tgctgtgcta
    12361 gtggtgtatc gcattgctga ttttccaaag cttgggccca gtaatcttgc aagagctgtt
    12421 catcgaatgt ctggtcatct gctaagatat tcagtttgac ttgtgcaata tctttaaaag
    12481 cgatagtcag atgctgagtc aatgaccgat atagcataat aggcaaaatt ttggaaaaat
    12541 gtagcgtaaa ttcccataaa cgcgatttac gatggaccac tacactatcc atttcaccag
    12601 cagtaagcag tggatgattt ttttctgctt cctctagttg gatttgttcc aacagttttt
    12661 caaataaatc tcgtttttct gacaaagata tacgcccttt ctgatgagaa acaatgcaat
    12721 tgatcgcatc ttatcctctt ctttttcagt accttttagt atactcgttt tttctgagtt
    12781 ttacattaaa aaattggaac tgcgattcaa atcgcagttc caattttaaa agcgaatcat
    12841 cagattgtca aaaacagctg attcagctat ttttattttc tgtgttttaa cgcttattat
    12901 tcgccttggt tcaagaggat tggtaaagta ttcgccaatt cttctttacg tacttcaacc
    12961 atttcgccag ttttcttgat tttcacttct acgattccat ccactgcttt tttaccgaca
    13021 gtgattctga ttggacagcc aatcaaatca gaatccgcga atttcactcc tgcgcgttca
    13081 tttctgtcat caaccagtac ttcatagcca gcttttgtca tcgcttcttc tagttcattc
    13141 gtcaggcttg tttggtattc gtcttttaga ttcatttgga cgatatgcag atcaaatggc
    13201 gcaattcctt ttggccaatt gattccttgt tcatctgaat gttgttctac gattgctgat
    13261 aataaacgac ttacaccgat accataacag cccataatca caaatttttc tcgtccattt
    13321 tcgtctagta cagttgctcc catagattca ctgtaacgag tgccgatttt gaatatatgt
    13381 ccgatttcga ttcctcgagt aaaggcaaga acaccgttgt tgtctggtga aggatctcct
    13441 tcttgtacaa aacgaagatc ttcataagaa agcacagtga aatcgcgttt tggattcaca
    13501 tttttatagt ggaatcctgt ttcgttcgct ccagtaatgg cattcgctaa atcttggaca
    13561 taacggtctg catatacttt tacgtcatct gaaacaccga ctggtccgac agaaccaaac
    13621 tcagcaccta gatatttttg tgcttcttct tctgttgctt cttctaaaaa gtcagcagat
    13681 aaaaagtttt tcagttttac gtcattgact tcatggtctc cacgtaccaa aacaaggaca
    13741 ggttgttcat ccgcaatgaa caatacagac ttgatgattt tttgaggttc aacagaaaag
    13801 aaatctgcta cttcgtcaat tgattttacg ttaggtgtag ctactttctc caattcaagc
    13861 tgtgtttcat gcgatttttt tgatacatag tagcttgtag ccatctccaa gtttgcagca
    13921 taatcacttt cagtcgaata acagatcgta tcctccccga tttctgagat cgccatgaat
    13981 tcctttgagt ctttcccgcc cattgcgccg ccgtctccga tgatcgagcg aaattctaag
    14041 ccacaacgct tgaatacttc ggtataggct ttttcgtaat ctttatatgt ctcgtccaaa
    14101 ctttcttccg ttgcatggaa agaatatgca tctttcatga taaactctct tccgcgaagc
    14161 aaaccgaagc gaggtcgttt ttcgtcacga tatttaggtt ggatttgata aagatttaaa
    14221 ggtaatttct tatatgaatt gatttcatta cgcatcaaat cagtaaaagt ttcttcgtga
    14281 gttggtccaa ggatcatttt tcgatcattg cggtctttga aacgatacaa gtttggtcca
    14341 tatgtttcgt aacgcccgga ttcttcccaa agttctgctg gcaagatggc aggcatcagc
    14401 atttctaccg ctccgatttt ttcaaattct tcccgcataa tgcgtttcag tttttccaat
    14461 acacgatttg ctaatggcag atatgaataa atacccgctg atacttggcg gatatatcca
    14521 gctcttagca agatttgatg gcttaatact tctgcatcat ttggaacttc gcgtaatgtt
    14581 ggaatcaaca tttttgattg tctcattcta tatactcctt tatttcctca aaatagttat
    14641 cgtttgttat tataccctat ttgtcaactt tttctagaaa aagaatcgtt gaatatcgtt
    14701 ccatgtaact agcaccatca acaacattaa aaatccaaag ccagctaatg tcaatattcc
    14761 ttctttttct tgacttaatg gtttcccgcg aatcccttca aaaatattca agactaattt
    14821 cccgccatct aaggcaggaa tcggaagcag attgacgatt ccgagattca ttgaaagaag
    14881 cgccatcaaa ctaataacag ttgttacacc ttgatttgct gcttctgaag acaattggta
    14941 catcatgaca ggtccgccta atttatctaa actgaaacct gtaaatagtg atcctaaggc
    15001 tttgaaaatt tccaatgaac cgctgaaagc ttgacgcgtc cctccaatga tcttatccat
    15061 aaaacctgta ttcattgggg cttttatacc aagttggcca actttttcgc catttgactc
    15121 tacagatttc ggtgtcacgt cgacagattg cacctgacct tctcgttcga tcttaaagtc
    15181 taatgtttta cctggatttt tcgtaatgac tgttgtcaga tcattccatg aatggatttc
    15241 ttttccgtcc acactgacta cctcatcatt ttcttttaag cctgcttctg ccgcagctcc
    15301 attaggcatg atctctccta cgcgattagt gttcgtcact tgaacaccac cttgcataaa
    15361 tgccagaatg atgaataaca cgattgccaa aataaagtta ttcatgggtc cagcaaagtt
    15421 ggtcagcata cgctgccaca atttagccga ttggaactgt acgtcttttg gcgcaattct
    15481 gatttctgtt ccgtcgtttt caataatcgt cgcatcgtga tcaacagggt aggttactac
    15541 ttctgtttcg tctccattca cataaccagt gatagtcagc tcatcttcta aatcataacg
    15601 gctcaattcc atcgggatag catttgtcaa ttggattttc ttacttaaat ttatcttctc
    15661 tacgatgccg tcagaattta gtaaaagaga aagaggcatt cctggtgcca tttctgtttc
    15721 atcatcccca ttgcctgcca ttcgaacata accgccaata ggtaataggc gaagcgtata
    15781 tgttgtcccg tcttttgctt gatgcccata aattttcgga cccataccga tagcaaattc
    15841 gcggacgagg attcctgatc gtttcgcaaa gaagaaatga ccaaactcat gaacaatcac
    15901 taatatacca aaaacgatga taaatgtcag aatcgttttc atagcttttt tctcctttac
    15961 ttgttttttg tgttttttat aaaacaacga taaaacacta taattttacc atagtatacc
    16021 aaagacacca atagtatcaa tataatgaaa aataaaaacc tgcgtctttt atgaaattca
    16081 caaagaaacg caggtatact tactaaataa tgccaaataa atgcatgata ggaaatacaa
    16141 acagcaaact gtcgaaacgg tctaagattc caccatggcc tggtaagata tttcccgagt
    16201 ctttcacatc ataatgacgt ttgattgcag attcgaccaa atcaccaaat tgtccgactg
    16261 ctgaaaaaat aatcgtcatc agaagcatga caaacatacc atgattgaat agttcttttg
    16321 ctgggtatag caataaataa agaaatgcga ctacaacagt actaccgata ccaccgagcg
    16381 caccttcaat cgttttgttg ggcgaaatat caggacttaa cttatgctga ccataacgtc
    16441 gaccaaccat atatgctccg atatcagttg cccaaacaat aaatagacca aatatcaaaa
    16501 cagccaagct ttctgttcgt gcattgacaa aattctggaa acctattccc acatacaagc
    16561 tgacaagcac aggaaaacct gcttcatcaa tcgtatacgt atttttagaa ataactgatg
    16621 ttcctaaaag aatcataact ataagataaa ataacataaa tgtacttaca ttctctggaa
    16681 gaaagaaaaa ccatctttct tttggcaaaa caagtaacac tgcaccaacg gcggataaaa
    16741 ctccttcaaa acttaagagt gtcaatcctt tcatccggaa cagctcgtaa actcctacta
    16801 ccgctaagat tgctgctgta agctcaaccg ctatgcctcc gatccatata atcggaataa
    16861 acaagactag cgccacagct gctgtgatca cacgttgttt catgactgat cccctttctc
    16921 atcttctgtt ttttttacac cgccgaatcg acggtctcga ttttgataag aggcgattgc
    16981 ttcttcaaga tgcgcaccat caaaatcagg ccaaagcgct tttgtaaaat acagctcact
    17041 atatgcgatc tgccataaca gaaaattact aattcgctct tctccacttg tacggatcat
    17101 cagctcagga tcttgtaact ctttaggcaa gaaacctgtc attaaatgct tagcaatcaa
    17161 ttcatcatcg atttcttctg cgtgtatttc tccttttgct acttcttcgg caatttcttg
    17221 gacagcagtc acgatctctg ctctacttcc ataattcaaa gcaaaattca ataccattcc
    17281 agtattgttt tttgtttgct caattgcacg tcttacagca tcttgcgtat gttctggcaa
    17341 tacgttttca taacccatga catgaacttt gacattttct ttaatcaatt ctggtacgaa
    17401 cgtatcaaag aagtcgacag gtagttgcat gagaaaactt acttcatctt ttggtcgctt
    17461 ccagttttca gtcgaaaagg cataaagcgt caacactttc actccaagcc ttgatgcttt
    17521 ttttgtgact ttctttactg tttccatgcc ttctttatgg ccagcaactc gtggcaaacg
    17581 acggttttgc gcccaacgac cattgccgtc catgatgatg gcaatgtgct gaggaattgg
    17641 tccatcggta ttaaattgaa attcgctttt ttcttgaata tatttgtttt tttgcggaaa
    17701 aaaacgtaac attctttttc ctcctatact taaaagattc ccactatctt aagtattata
    17761 gcaatatcta actgtttttc ctatgaaatc attgtttttt tatttaaaaa ctgaataatt
    17821 ttttcttttt ttaattttta aataaaagaa atataaataa aaacagagga agcggaatga
    17881 tccgcccctc tgtttttatg attttattaa acttccaata attctttttc tttatcagca
    17941 gcgatcttat ctacttcttt aatgctgtta tctgtcaatg tttgtacgtc tttttctaat
    18001 ccgcgcaaat catcttcggt aatatcacca tttttttgtt gttttttata ttcatcgatc
    18061 gcatcacgac ggatgttacg aatcgcgatt tttgcatttt ctgcttcttt tttcacatct
    18121 ttagctaatt cttttctgcg ttcttctgtc agttgcggga taactaagcg aatgacattt
    18181 ccatcattgg ttggactgat tccgatatca cttgccataa tagctttttc aacatcttga
    18241 agaatgctct tgtcaaaagg tgtgatcatt aaaacacgtg cttctggaat ttggattgat
    18301 gccatttggt tcaatggtgt tggcgcaccg tagtagttca cagtaatacg gtccaaaagg
    18361 ctagcgttcg cacggcctgc gcggatttgc ccaagttcac gttgaagatt ttgtgctgct
    18421 tttttcattt tttcttttgc ttctgtcata attgcatctg ccatttttat ttccccctta
    18481 cagttgttcc gatattttcg cctaagattg cacggcgaat atttccgtgt tcatttaaat
    18541 tgaagacaag cagtggaata tcattatcca tgcttagtga acttgcagtt gaatccatga
    18601 cttgtaatcc tttggcaata acttccagat gagtcagttc ttcaaatttt actgcatttg
    18661 catctacttt cggatcagca gaataaacac cgtctacatt gtttttagcc atcaggataa
    18721 catctgcgcc gatttctgcc gctcgtaatg ctgctgttgt gtctgtcgag aagtacgggt
    18781 tgccggtacc gcctgcaaag ataacgatcc gtcctttttc taaatgacgt tctgctttac
    18841 ggcgaatata tggctctgcg atttgacgca tttcaatcga agtttgcacg cgtgtcggta
    18901 cacccacgtt ttccaacgta tcctgtaaag ctaaggcatt cataactgta gctaacatac
    18961 ccatgtaatc agcttgagca cgttccatgc ccatttgtgc tccgatttgt ccgcgccaga
    19021 tatttccgcc acccacaacg attgccattt caacgcccag ctcgtgaact tctttgattt
    19081 cttggatgat ttctttgatt actggtggtt tgattccaaa tcctgcatcc ccagctaaag
    19141 cttctccact caattttaag actacacgct gatatttcgg tgtgaccatg ttcattcctc
    19201 caatattttc tattgccatt ttaccatact tagatgattt cgacactcta agactggttt
    19261 ttcttgtttt gcttaaaaaa agggagcgca caaaccgtgc gttcccgtct gttattcaac
    19321 agaattattt tttcacttgg ctcataactt cttctacaaa gttatcttcg cgtttttcga
    19381 taccttcgcc aacttcgaaa cgtacgaatg ttttaacagt tgcgcctttt gatgcaacgt
    19441 atttttcaac agtcatatca ggatctttaa cgaatggttg gtccaccaaa gcgatttctg
    19501 ctttgaattt cttcaagcgt ccttctacca ttttttcaac gatattcgct ggtttgcctt
    19561 cgttcaatgc ttgttctgta agaacagttt tttcatgttc taattcagct tctggaattt
    19621 gtgattcgtt tacataacga ggattgatag ctgctacgtg catagctacg tctcttgcaa
    19681 ctgtttcgtc agttgttcca tctagaacag tcaatacggc aatacgtccg cccatatgca
    19741 agtatccacc aaatgcagca ttgtcgtctt tttctacaac ttcaaagcga cggaagctga
    19801 ttttttctcc gataacttga gttgcttcga tcaagtcaga ttcaattgta cctttatctg
    19861 ttttgatttt cattgcagct tccatgtctg ctggtttgtt ttcagcaaca agttctgcaa
    19921 tttcttttac taaatcttgg aacatttcgt ttttagaaac aaagtctgtt tctgagttta
    19981 cttcaacgat tgctgcagtg ttacctttca cagcaactga agccaatcct tcagctgcaa
    20041 tgcggtcatt tttcttcgca gcctttgcca ttcctttttc acgtaaaaga tcaactgctt
    20101 tttccatgtc gccttctact tcaactaatg cttttttcgc atccatcatt cctacgccag
    20161 tcatttcgcg tagttctttt accattttag ctgtaacgtc tgccatgttt aactcctcct
    20221 gtgtgttttt ctttttaaaa aaagctgctt caaaggagag tgaggcttgt cgcccagcct
    20281 ttgaaacagc tccatcattc aaaattattc tgctgaagaa ttgtcgcctt caacaacatc
    20341 tacgatttct tcgattgatg ttgctgtgtt ttcttctgtg aaatcttctt caactacttg
    20401 atcttcacct tggtttcctt cgatgaaagc atcagccatt tttgaagtaa tcaatttaac
    20461 ggcacgaatt gcatcgtcgt ttgaagggat tactacgtcg atttcatctg gatcgcagtt
    20521 tgtatcaacc atagctacga ttgggatatt taatttgtgt gcttcttgaa cagcaatacg
    20581 ttctttacgt gggtcaacga tgtacattac atctgggatt cttggcatat cagcgatacc
    20641 gcctaagaat ttttcaagac gttcacgttc tttgttcaaa ccagcaactt cttttttagg
    20701 tagaacttca aaagttccat cttcttccat tgcattgatt tgtttcaaac ggctgatacg
    20761 tttttggata gtatcccagt ttgtcaatgt tccgcctaac caacgatggt taacgaagta
    20821 ttgtcctgca cgagttgctt cttctttgat tgcttcttgt gcttgttttt ttgtacctac
    20881 gaataatgct acgccgcctt cttcagcaac gctcttcatg taatcataag ctgcatctac
    20941 taatttaact gttttttgca agtcaatgat gtagattccg tttctttctg tgaagatata
    21001 tttcttcatt tttggattcc agcgacgagt ttggtgacca aagtgtacgc cggcttctag
    21061 taattgtttc atagaaatta ctgccatgtt tgtttcctcc gatttggttt tatttttcct
    21121 cttcttatct tctaccttgc cggcaaactt tttcaagcac ctaccgacaa tccaataaga
    21181 atgtggattt gctgatgcat aaagcaccct cagctattat acagacaaaa gatccgtatc
    21241 gcaagagcaa atatactttt ctgctcaaca ttcaatagtt tacctgaaag ataaaaagaa
    21301 ttcaagaaaa acagtagatt tctctttgtt tctttattat cctttttcca taaaataatt
    21361 ttaggtataa aagacgaata ttattgggca atccttcttt tttttgttat gatacatgtg
    21421 aaatctttcg taaaggagaa agaaaatgcg caaagctcaa agacatttgc tgattaaaca
    21481 agtcattgaa gaattcccga tccgtacgca agaagaacta ttaaacaaac ttgggcatta
    21541 tggcgttacc gccacgcagg caacgatttc tcgagatatc cgtgatctaa aaatcgtgaa
    21601 ggcacctgat gaaaatggcg tttcccgctt cgtattgttt cgcgaaaaag gaactcctga
    21661 gactaggact gaggaagagg atcggctggt tcaaatgatt gaagacattg tattgaaagt
    21721 cgaacgagtc cactttttga cgatcgtcaa taccttgcca gacaatgctc atttatttgc
    21781 atctgtttta gatgagatca aacctccctc tattgtcagt acaattgctg gattcgatac
    21841 gatcatggtc atctcggaaa atgaggagga cgcaaaacga gtagaagaat ttcttcacca
    21901 tccaactgaa gtatcacttt tttaatcaga gcacgtattc ctaatatgga atgcgtgttt
    21961 ttttattttc aatattttcc ttattaaata aacctttaca ctctttacaa aaatacatca
    22021 ttttttattc aattttttca acaccttgat tgaatcacaa taatcatcat ttatattgga
    22081 tgttaacaag agcagcttct tgctctttgt gtatttcaaa aaagaaatga aaggaaatca
    22141 tatgtataaa ttattaactc ctggaccatt gacgacttct gaaacagtga aaaatgctat
    22201 gctgatcgat cattgtactt gggatcaaga atacaaagaa attacacaat ggataagaaa
    22261 aaaattattg gatcttgctc aagtatcgga aggaatatac acaacggtct taatgcaagg
    22321 tagcggctcc tttggggtag aatcggtatt aagttctgtg atcaggccag aagatactgt
    22381 actgatttgt tcaaacggcg catatggaca acgaatgatc aacatgtgcg aatgtctgaa
    22441 actgaactat accgtttatg aggtatcgga acatcaaatc ctccaagctc atgtgattac
    22501 acagctgatt gaagagaatc cctctatctc cgcactagca atggtccata gcgagactac
    22561 ttccggtatt ttgaataatt tggaagagat tgctgctgtc acacaagaaa aagatctttt
    22621 gtttatagtg gacgcgatgt caagctttgg tgggataccg attcgtgtag ccgaactagg
    22681 gattgatttt ttgatttcca gctcaaacaa atgtattcaa ggtgttccag gcttttcttt
    22741 tgtacttgct aataaagcgg aactagaaaa gcgaaaaaat gtgagtcgaa gtttgtcact
    22801 tgatctatat gaccagtacc gcgtgatgga aaacgagaat ggcaaatggc gtttcacttc
    22861 ccctacccat acggttttgg cttttcaaca agcgctgaag gaactagagg cagaaggagg
    22921 aatcgaaact cgatattcac gttatctcgc caataatcat gtactacgac aaaaaatgac
    22981 agagatgggg ttccagcctt tcattcaaga atatcagggg ccattcatca cctcttttct
    23041 ttaccctaag gactggcgat ttgattttaa tcatttttat cagtatttaa agcaaaacgg
    23101 atttgtgatc tatcccggga aaatcagcga tcatgaatgt tttcgtatcg gaaatattgg
    23161 cgagatctat ccggaagata ttttggaact gacagcaatt atcaaagact ataaggagaa
    23221 cgttaatgat taaaactgta atttttgatt gggcaggaac aactgtggac tttggctgta
    23281 tggctcctgt ccacgctttt agaaatgctt ttctagaaaa aggaatccaa ctgactgaca
    23341 aagaaatccg cgaaccgatg ggaaaattaa aatgggatca tatccaacag cttctttccc
    23401 tcccttctgt caaaaaacaa tggatagcta tttatggaca actacctcag gaaaaagagg
    23461 tggaggaatt gtatcaacaa tttgaacatt atctgtttaa agatttggtc aagcattcta
    23521 ccttgaaacc cgacacattg gaaacgatcg aacggttgag aaacgctggg atcaatattg
    23581 gttccacgac tggatttact gctcctatga tgacaatcgt agcagaaacc gcaaaaaaag
    23641 aagggtattc accagacttc atggcaactt ctgaagacgt cgaagggtat ggtcgaccgt
    23701 ttccttatat gatccataaa aacatgcagt acttcaaaaa caagtcggtt gatgaagtaa
    23761 tcaaagtcgg agatacggtc tcagatatcc aggaagggaa aaatgccgga gtgttgacag
    23821 taggtgtaat tgaaggtagt tcgctaatgg ggatttctta tgatgagtac caaaaattag
    23881 agatggggaa aaaagatcgt ttaaaacagt ctgttgctct tagattccaa caagctggcg
    23941 ctgatatttg tgtaaacaat ttaaaagagt taacagaata cattttgtac gctgacaaga
    24001 atccagaatg acttttatac aaaatcagag gtcgtgaaaa agctgtactg catcaagtaa
    24061 taagaacagc caaacaaaaa tagctcctca tatttttcgt ttggttaggc ttattaccgc
    24121 agatgcaagc ttttgaacac cgtttattcg aaaaaaaaag ggagctgtga cacgactttt
    24181 gtcacagtcc ccttatttac aaacaaacag tgtttaagag acaacctctc cactaaacgg
    24241 tgttcattca gctgactctc ggtatttgct caaaaaacga taaaatttga aaagctattt
    24301 tctcttttgt ttctctaata ctcggatcag aacgctgatt tcacattctc tttttcttac
    24361 atcttatctg gtgcatgaag tcctagcaaa cgaaggtctt ctttcaataa tacagtcact
    24421 gcataaacta gagctaagcg tgcttctttt tgttcatcat cagctaaaat cttcgtatga
    24481 gcatagtatt tgttgaatgc ttgtgctaat ttgattgcat gtttcgcaat cactgacggt
    24541 tcgtattttt ccccagcaga caagaccgtt tcagggtatt tttgaactaa tttaaccact
    24601 tcccagctgg tatcgtcatt caatgcatag tctgctgttt ctgaagggac aaatcctgct
    24661 ttttccaaca ggctgactgc acgagcatgt gtatattgca cataaggtcc agtttctcct
    24721 tcaaatcgaa caacttcttc caggttaaag tcaaatgtat tcagtcgatc gtttttcaaa
    24781 tcgtggaaaa tgactgcccc aaccccaact tgtttagcta cagcatcttt gttttccaaa
    24841 tcagggtttt tctcgctgat ttgttcttta gcagattgga ttgcttcatt taatacttct
    24901 tctaataaga cgatctttcc tttacgagtt gataattttt taccaccttg cgtgatcaaa
    24961 ccaaatggaa tatggcgcat atcgtcagac cagtcaaagc ccatttcctt caagacagct
    25021 ttcaactgtt taaaatgata gctttgttca ttccctacta catatagaga ttgtttgaag
    25081 tcgtaagtac gtttacggta caatgcagca gctaagtcac gtgtaatgta tagtgtcgca
    25141 ccgtctgact tcttaatcaa cgctggattc aggtcataag cagataggtc aacgatctct
    25201 gcacctttat cctcgttcag caaatgtttt tcttctaaaa gtttgacgat ttcatccatc
    25261 ttgtcattgt agaaagcttc accgttcaac gaatcgaaac gtacttccag cagatcatag
    25321 attttattga attctttcat cgattcatca cggaaccatt gccataattg aatagcctct
    25381 tcatcgcctt cttccagacg tttgaaccaa gcacgagctt cttcatttaa ttctggttct
    25441 gtttcagcta cttcatggaa ttggacatat aaacgaagca attcattgat tggttctgct
    25501 ttaacagctt cttctgtacc ccattttttg taagcgacga tcagttttcc aaactgtgtt
    25561 ccccagtcac ctaaatggtt gatgcggatt ggctgataac cgattttttc cataatgaaa
    25621 ccgatcgaat taccgataac tgtcgaacgc aaatgtccca ttgagattgg tttggcaata
    25681 ttaggagaag acatgtcgat tggtactgtt ccttgattcc cgatattgct atccccataa
    25741 tgttcttttt ctttcactac tgtttgcaaa acttttttgc tgataagttc tttattcatg
    25801 aaaaagttca agtaaggtcc gacaacttcg attttttcaa agttggcaga atcgattttt
    25861 tctgctaaat ctgcagcgat ttgctgtggc gcttttcggt aaacttttgc taatgaaaag
    25921 gctggaaatg caacatctcc gtgttcagct gattttggat tttctagtaa ttgttcgact
    25981 tgttccagtg ttaaatcatc tttgacagcg tcatagacag cttttgcgac aagatcttta
    26041 ttattcatct ttattcctcc taaagtgctc ccttgattgt taaacaaaaa aaatctctag
    26101 cgacggcata cttagtatgc catcactaga gacgagattt cccgcggtac cactccaatt
    26161 gtcctaaaaa aggaccagct ccatctgata tcggtagacg accgtctgtt taaaacagaa
    26221 ttctccaagt gcgcttcgtt gtatcttctt cattcggctt ccaccacttc cgaattcgct
    26281 agccaagaat gatacaagta ctctcttgtt caacaaatct tagtcttatt aaactttctt
    26341 gaattatatc agaaaaaaaa acgaaaggct agtcgtttct gataaaaaaa caatccagat
    26401 ggcctaaagg agaagaaata ccacctggat agctataaat catttcgtaa atacgaaaga
    26461 cttaacaaat taatcagcta cgataatcgt tccttcttca gaagctaaaa gattctcgat
    26521 attttctaaa gaagtgatga ttgccttagc gtttggtttt gcttcaacaa atgcaatagc
    26581 tgcctctact ttcggaagca tgcttcctgg agcaaattgc ttttcatcaa tgtattgttt
    26641 catttctgaa acagtaacag tttctaattt cttttgatct ggtttttggt aattgacata
    26701 cacattgtct actcctgtca atacgatcag caaatccgca tcgatgattt cggctaattt
    26761 ttctgaagca aaatctttat cgattacggc ttctcgtcct tctaatccag tagctgtttc
    26821 tacaacagga atcccaccgc caccaacaga gactgtgata actccttgat cgaccagcgt
    26881 ttcgatgaca cgtgcttctt taatcgagat gggtttaggg gaagcgacta cttttctcca
    26941 tccacgtcca gcatcttctt tgaatgtcac agtggagtca gcattcattt gttctttggc
    27001 ttcttcttcc gtgtagaatg gaccgactgg tttacttgga tttttgaatg aaggatcatt
    27061 ttcatccaca ataacttgag tgactaaaga aaccacatct ttatcgatcc ctttttcctt
    27121 cagtacttcg cccatggcgt tttgtaacca gtaaccgata gatccttctg tcattgcaac
    27181 acatgtatct aaaggcattg ccggtgtttt ctcagaatca gcagcttgct gctgaatcaa
    27241 taggttaccg acttgcggac catttccgtg ggagatgatc aattcatctc cttgttcgat
    27301 aaatttcact aaatactttg ctgtttccat taacgcttct tgttgggctt ttgcacttgc
    27361 atccgtagac aagatggcat tgccccctaa agcgacaact acttttcgtt tggccatttc
    27421 attcgtcctt tcttcagttc taccgaattt tctagataac aaaacgagcc agcgttttgt
    27481 gattttccct caatgctgac tcgttttttc gtgagatgaa tgtggttatg cttaaacgcg
    27541 agggataaac aagttaccta atgttgctgc catgatcgct ttgattgagt gcatacgatt
    27601 ttctgcttgg tcaaattgac gagcatattt gctgcggaag acttcatctg ttacttccat
    27661 ttcagtgatg ccaaagcgtt ctttcatttg ttcaccgtaa acagtgtttg tatcatggaa
    27721 agctggcaag cagtgcaaga agatcaaacg atctgtgttg tgtgtttttt ctaccatttc
    27781 catattgatt tggtaaggtt tcaacaattt gatacgttct tcgaatttat cttcttcacc
    27841 cattgatacc catacatcag aataaaggac gtctgctccg tctacacctt tatcaacatc
    27901 gtcggtaatc atcaattgtg caccggattt ttcagcaaag ccttctgcca ttttgacgat
    27961 ttcttcttca ggttgtaatt cttttggtgc aacgatacgc atattcgctc ctaaaattgc
    28021 acctgtgact aataaagagt tagccatatt gtttcgacca tctccgcagt aagcaacagt
    28081 gataccttct actgttccaa agttttcttg gatagttaaa aagtcagcga tcatttgtgt
    28141 tggatgccat tcatcagtca agccattcca aactggaaca ccagagaatt ctgctagttc
    28201 ctctaccatt ttttgactga atccacggaa ttcgattccg tcaaacatac gtcctagtac
    28261 tttagctgta tcttctgtgg attctttttt acctaattgg atatcatttg cacctagata
    28321 ttcaggatgt gcacctagat cgatcgctgc agtagtaaat gcagaacgag tacgtgtaga
    28381 tgttttttca aataaaagcg caatattttt tccttctaga tagtgatgtg ggataccacg
    28441 ttttttcaag tctttcaagt gttctgaaaa atcgatcaaa tattgtaatt cttcttttgt
    28501 aaagtctttt tctgctaata agcttcttcc ttggaatact gattctttca tattaaacat
    28561 tctcctttag attgttttta tttaagatta aagaggaaat cccgacggca gctgacagta
    28621 agactgccgt caggaaacaa attacttcaa gtcttcacgg acaagtggtt ggctcatgca
    28681 gcgtggacca ccacgacctc gtgacaattc acttgaattg atttctaaca ctttgatgcc
    28741 atagctacga agcaattcgt tcgatacata atttcggtta taagtgacta caacacctgg
    28801 agcgattgcc aatgtgtttg atccatcatt ccattgttct cgaggtgcaa cgatctcatc
    28861 tccattacca gttgggatca gtacaagatc atctaatcca agagcagctt tcatcgtttc
    28921 gtgtaagtta tctgaatgag taatcttgat atcatcacca tctggttcga ttgtaaagac
    28981 atccatctta ccgtctttac tttgaattgc tggatggata gtgaatttat cgtgatctac
    29041 cattgtaaat acggtatcca aatgcatcat tgcacggttg ttcggaattt tgattgccaa
    29101 cactttttca aatcctgaat tttttgcgaa taggtggcgt gctaattttt ctaaagcttt
    29161 cgcattagtt cgttgagaaa tcccaacagc tactacttta tcgcttaaga tcaattcgtc
    29221 tccgccttcg atatgatctg gattttcacg atccaaccat acttcgattc ctttatttgc
    29281 aaatcttgga tgatgtttca aaatatattc tgtaaacatc gattcacgac gacgtgcttc
    29341 aaaagtcatc ttattgactg tcatcccatt tcccattgat gcggaagggt cgcgtgtaaa
    29401 gtacaagttt ggcattgggt ccatgtaaaa tggatagtca tcgtctgctg acagatcata
    29461 tagactgcta gaacgtactt cgatatcttt tgtacgaacc ccagccatga ttttatctac
    29521 catttcttgc gtttccattg atagaaggaa ctcatgaaga ccctctctta cagcattcga
    29581 tgcaatatga gattcatcca acattttatt caagaattgt tctttgacat tgcctgcgtc
    29641 aatcgcttct gccgctaatt tttccaagta aagagtctcg acgccttcat tttgcaatgt
    29701 cttcgcaaag ttgtcatgtt cttcttgagc aatcggaaga tatggaatat catcgaacaa
    29761 cagacgatcc ataatatctg gtgtcaaatt ttccacttct tgtccaggcc gtttcagtaa
    29821 aactgtcttt aatttcccta tttcagagaa aacgtgaata ggtttatcca tgttgtgttg
    29881 cctccttctt tttgattaca tgtataggat atcctccttt tgtaatcact ttcataattt
    29941 tgtctcattc aaaatgagac attcctcaca ttaatattcg ataattaaat aattaaacgt
    30001 ttttctattt ttaagcg
//
LOCUS       DAMEEU010000030        29096 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.031, whole genome shotgun sequence.
ACCESSION   DAMEEU010000030 DAMEEU010000000
VERSION     DAMEEU010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 29096)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29096)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29096
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.031"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..1030)
                     /locus_tag="PB779_001335"
     CDS             complement(<1..1030)
                     /locus_tag="PB779_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0738868.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="PB779_001336"
     CDS             complement(1112..1801)
                     /locus_tag="PB779_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDE0738869.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
     gene            complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="PB779_001337"
     CDS             complement(1907..2275)
                     /gene="rplL"
                     /locus_tag="PB779_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HDE0738870.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(2328..2831)
                     /locus_tag="PB779_001338"
     CDS             complement(2328..2831)
                     /locus_tag="PB779_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HDE0738871.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(3035..3162)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="PB779_001339"
     CDS             complement(3241..3930)
                     /gene="rplA"
                     /locus_tag="PB779_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HDE0738872.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="PB779_001340"
     CDS             complement(4034..4456)
                     /gene="rplK"
                     /locus_tag="PB779_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HDE0738873.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            4799..5467
                     /gene="sdaAB"
                     /locus_tag="PB779_001341"
     CDS             4799..5467
                     /gene="sdaAB"
                     /locus_tag="PB779_001341"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HDE0738874.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            5480..6352
                     /gene="sdaAA"
                     /locus_tag="PB779_001342"
     CDS             5480..6352
                     /gene="sdaAA"
                     /locus_tag="PB779_001342"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HDE0738875.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(6443..7462)
                     /locus_tag="PB779_001343"
     CDS             complement(6443..7462)
                     /locus_tag="PB779_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HDE0738876.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(7635..8540)
                     /locus_tag="PB779_001344"
     CDS             complement(7635..8540)
                     /locus_tag="PB779_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDE0738877.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="PB779_001345"
     CDS             complement(8599..9144)
                     /gene="nusG"
                     /locus_tag="PB779_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HDE0738878.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(9245..9415)
                     /gene="secE"
                     /locus_tag="PB779_001346"
     CDS             complement(9245..9415)
                     /gene="secE"
                     /locus_tag="PB779_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HDE0738879.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="PB779_001347"
     CDS             complement(9439..9591)
                     /gene="rpmG"
                     /locus_tag="PB779_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDE0738880.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            9753..10397
                     /locus_tag="PB779_001348"
     CDS             9753..10397
                     /locus_tag="PB779_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDE0738881.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(10453..10956)
                     /locus_tag="PB779_001349"
     CDS             complement(10453..10956)
                     /locus_tag="PB779_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDE0738882.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(10969..11015)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            11553..12518
                     /locus_tag="PB779_001350"
     CDS             11553..12518
                     /locus_tag="PB779_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDE0738883.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(12617..13789)
                     /locus_tag="PB779_001351"
     CDS             complement(12617..13789)
                     /locus_tag="PB779_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738884.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(13776..14921)
                     /locus_tag="PB779_001352"
     CDS             complement(13776..14921)
                     /locus_tag="PB779_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738885.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(14935..15867)
                     /locus_tag="PB779_001353"
     CDS             complement(14935..15867)
                     /locus_tag="PB779_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738886.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            15984..17063
                     /locus_tag="PB779_001354"
     CDS             15984..17063
                     /locus_tag="PB779_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDE0738887.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            17060..17678
                     /locus_tag="PB779_001355"
                     /pseudo
     CDS             17060..17678
                     /locus_tag="PB779_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
     gene            complement(17788..18015)
                     /locus_tag="PB779_001356"
     CDS             complement(17788..18015)
                     /locus_tag="PB779_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDE0738888.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(18118..20706)
                     /locus_tag="PB779_001357"
     CDS             complement(18118..20706)
                     /locus_tag="PB779_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HDE0738889.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(20726..21385)
                     /locus_tag="PB779_001358"
     CDS             complement(20726..21385)
                     /locus_tag="PB779_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDE0738890.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="PB779_001359"
     CDS             complement(21434..21937)
                     /gene="trmL"
                     /locus_tag="PB779_001359"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HDE0738891.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(22158..23024)
                     /locus_tag="PB779_001360"
     CDS             complement(22158..23024)
                     /locus_tag="PB779_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDE0738892.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            23133..23774
                     /locus_tag="PB779_001361"
     CDS             23133..23774
                     /locus_tag="PB779_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HDE0738893.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="PB779_001362"
     CDS             complement(23836..25197)
                     /gene="mgtE"
                     /locus_tag="PB779_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HDE0738894.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(25215..26114)
                     /locus_tag="PB779_001363"
     CDS             complement(25215..26114)
                     /locus_tag="PB779_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HDE0738895.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(26116..26913)
                     /locus_tag="PB779_001364"
     CDS             complement(26116..26913)
                     /locus_tag="PB779_001364"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HDE0738896.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(26891..27595)
                     /locus_tag="PB779_001365"
     CDS             complement(26891..27595)
                     /locus_tag="PB779_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HDE0738897.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            27726..28301
                     /locus_tag="PB779_001366"
     CDS             27726..28301
                     /locus_tag="PB779_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HDE0738898.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVGDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            28419..29096
                     /locus_tag="PB779_001367"
     CDS             28419..29096
                     /locus_tag="PB779_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HDE0738899.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         8560 a         6167 c         5231 g         9138 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
     1861 gcaccgaaat ccaacatagg atctcagtgc ttttaaatag taaaaattat ttaacagtta
     1921 cagatgcgcc aacttcttca agtttagctt tcaattcttc agcttcttct ttagatacgc
     1981 cttctttaac tggtgcagga gcgccatcaa ctacagcttt agcttctttc aagcctaaac
     2041 cagttgcttc acgaactgct ttgataactt taactttttg gtctccagct gcagttaatt
     2101 ctacagtgaa ttctgtttgt tcttcagcag cagcagcgcc accagcagca gctacagcta
     2161 caggagcagc agcagatacg ccaaattctt cttcaatagc tttaactagg tcgttaagtt
     2221 ctaggatagt tgcttctttt aactcagcaa cgatgttttc aatgttcaat gccattataa
     2281 tttcctccgt ttaattgttc ttttttattt aatgctttat gcggcaatta agctgcatct
     2341 ccatcttctt tgtctgccac tgctttgaca gcgtaagcca cgttgcggac tggcgcttgt
     2401 agtacagata gcaacataga tagaagtcct tcgcgatttg gcaattttgc caatgctgtg
     2461 atttcttcca atgaagagac tttaccttcg atgataccgc ctttgatttc taatgctttt
     2521 gcttctttag caaattcgtc catgattttc gctggtgcga ctacatcttc gttactgaat
     2581 gcaacagctg taggtccagt gaatacttcg tccatgcctt caaggccagc ttttttagct
     2641 gcacgtgaaa gaatagaatt tttgataact ttcatttcta cgttagcatc acgaagttgt
     2701 ttacgtaaac gtgttacttc atcaactgtt aatccgcggt agtcaacgac tactactgat
     2761 gcagctgctg taaatttttc gcttacttca tcaacgattg ctgctttttt tgcgataatt
     2821 gcttcactca tttttgagtt tcacctcctg aattttgatg gaagagtttt ttgcactgaa
     2881 aaggcaagtc acttttatag ttactttgct caaccagtat tattcatcac ctattcactt
     2941 cgttcatagt gattctactc gctttgctcg aaaggaaact cctttcgctt tgctcaacca
     3001 gtattgttca tcatctcttc acttcgttca tagtgattca caataaaaaa ctctatgcca
     3061 ccgcagacat agagggacta ttgaatatat tcaataaacg tcctcggtag gaaattaagg
     3121 cttgatgcca cctactgtct tcggtacaag ttaattatta acctcaacta gcttagcatg
     3181 ctaaactagt tgagtcaaga attatttttc agttggatca atcaacattc taatatttaa
     3241 ttagaaagaa gcttggtcaa catggatacc aggtccaaat gttgttgtga tcgttacatt
     3301 tttcatgtat tgacctttag ctgctgatgg tttagctttt agcaatacat catggattgc
     3361 tgcaaagttt tcaactaatt tttcatcgtc aaatgaaact tttccgattg gtacatggat
     3421 atttccagct ttgtccacac ggtaagttac tttaccagct ttcacttcgt ttactgcttt
     3481 tgttacgtcc attgtaactg taccagtttt agggtttggc attaagcctt ttggtcctaa
     3541 tactcgtcct agacgaccta cagtagccat catatcaggt gttgcaacaa ctacatcaaa
     3601 gtcaaaccat ccgttttgga ttttttgaac catgtcgtcg tcacctacga aatctgcacc
     3661 agctgcttca gcttcttttg ctttgtctcc tttagcaaaa actaaaacag tttgtgtttt
     3721 accagttccg tttggtaata caacagcacc acggatttgt tggtctgctt ttttagggtc
     3781 tacgttcaaa cggtatgcaa cttcaactgt tgcatcaaat tttgcaatgt ttgtttcttt
     3841 tgctaaagct actgcttcgg caacaggata aactttactt gaatcaactt tttttaatgc
     3901 atcttgcatt tttttgctct ttttagccat tttggttcct ccttgattgt ggttataacg
     3961 gttgtacctc ccacgtgttc tatatctttc aatatagagc caactgagaa gctgctgtct
     4021 tagggtgtat agattattct acagtgatcc ccatgcttcg tgcagttcct tcaaccatgc
     4081 gcattgctgc ttcaacgtta gctgcgttta ggtcttccat ttttaattca gcgatttctc
     4141 ttacttgatc gctagaaact ttcgcaactt tatttttgtt tggttcgcct gaaccttttt
     4201 cgattttagc tgcttttttc aatagaacag cagctggcgg tgtttttgta acgaatgtga
     4261 atgaacggtc ttcgtataca gaaataacaa ccggaatgat caaacctgct tgatcagctg
     4321 tacgagcgtt gaattctttt gtgaatccca tgatattgat acccgcttga cctagtgcag
     4381 gacctactgg tggagctgga gttgctttac ctgcaggaat ttgcaattta acgatttttt
     4441 ctactttctt tgccacgaga catacctcct taagtccgtg atgtggttaa ttggagatgc
     4501 atatttctcc tcccacgttt tatctgatct gaaaaaatcc agacaaataa tgtgcaaaac
     4561 aatgcacact ggtacagtat agcaaattta tttgtttttt caagattttt ttctgctatt
     4621 tttacatttt gcttgaataa acgctaaatt tattctaaaa aaacaacaat ttttcgttct
     4681 catttcttct tttatgttac acttgcgcta gcatggttca acagatgaaa gcaaacaata
     4741 acacggtttt ttagaccctt gtacaaagat tcctacataa caaaatgagg tggagaaaat
     4801 gaaagattta aggtatagaa gtgtctttga tattattgga cctgtgatga ttggtccaag
     4861 tagctctcac actgccggag ctgctagaat cgggaaaatc atacgtagta tatttggcga
     4921 acagcctgat tctgtagata tttatctata tgaatcattt gcaaaaacct atcgggggca
     4981 cggaacagat attgcattag ttggcggcct gttagggatg gaacccgatg atgaacgttt
     5041 agctgattct ttgaaattgg catatgaagc cggtatggaa gtcttgtttg ttcctaagag
     5101 tgaaaaagcc gaacatccaa actctgtaaa gatgcttcta aaaaaaggaa cacgaaagct
     5161 ttcagtcact ggcatttcga tcggcggtgg caatatccag atttctgaat tgaatggatt
     5221 caaaatttct ttaagcatgg gtactcctac cttgatcgtt gtccaccaag atgttccagg
     5281 tatgattgct aaagtgacta gtatactttc tgagaccaat acgaatatcg gcactatgac
     5341 agtgacacgg gaatcaaaag gtgaaaatgc cattatgata attgaagtag atgatcctca
     5401 agtagaagaa acggtaaaaa gactcaaaca gctgccaaat atcgacagcg taaattattt
     5461 cgattaagga gctaaaaaaa tgtttttatc gattgaagaa ttagtagatc aagcaaaagc
     5521 ttatccaagt gtagcagaat tgatgattgc agttgaaatg gaaatgagtg gccgttcccg
     5581 tagtcacatc atcgagatca tggaaaaaaa cctctcagta atggaacaat caatcaacga
     5641 gggaaaagaa ggtgttacct ccgtcacagg aattaccggt ggtgatgcaa aaaaattaga
     5701 tgattattta aatgaggcag actttttaag tggagaaaca atcttaaaag ctgtacgcaa
     5761 tgctgtagct gttaatgaag tcaatgcaaa aatggggttg atttgtgcta caccgactgc
     5821 cggaagcgcg ggtgttgttc ctggtgtgct gatggctgtc cgagatcggc ttgatttgac
     5881 acatgaacag caattggaat tcttatttac cgctggcgct ttcgggttag tcatcgcaaa
     5941 caacgcttct atcagtggtg cagaaggggg atgtcaagca gaagttggtt ctgcaagtgc
     6001 aatggcagca gcagctttgg tttgtgcaaa aaatgggact cctcatcaag cagcacaagc
     6061 agtagccatt acattgaaaa atatgatggg actgatttgc gatcccgttg caggcttagt
     6121 tgaagtcccg tgtgtcaaac gtaatgcttt aggctcttct caagctttta tctctgctga
     6181 tatggcatta gcgggtatcg aaagtgtcat tccgccggat gaagtcgttg ctgcaatgta
     6241 ccaagtcgga cgtcaaatgc cgtcgatttt caaagaaaca gcagaaggtg gcttagctgt
     6301 tacgccaact gctaaacgac ttgcggaaga gattttaaat aagagggcgt gataaagctc
     6361 cttaatttcg agtattaaga gattagttat cttcataaca aaaaacgaag agaggactaa
     6421 ttgcccttct cttcgttttt tattaatcca tcaatttcgt attttttact tcatcgatcg
     6481 tttttgttcc tgcaagttgc atcgtgatcg acaattcttt gttcaggtgt tcaaaaacag
     6541 atgttactcc ttctgcccca cctagattca acccataaat cactggtcgg ccaatcgcaa
     6601 ctaagtcagc accacttgcc agagctttga agacatgctc tcctcgacgg acaccagagt
     6661 cgaaaatcac tggtacacgt ttgttgacta cttcggcaat ttttggcaat acttcaaagg
     6721 acgcaggacc tccatctaat tgacgtccac catgattgga tacccagata ccatctgccc
     6781 ctgcagagat agcgattact gcatcttctg gcgattgtat tccttttacg ataactggaa
     6841 gatgggtgat ttctttgatt gttttgatgt catctggtgt caagccttgt tttgcagctg
     6901 cataaatttc tgcgattcct tttccttcgc cattaccact tgcactttgt tcgctatacg
     6961 cagctaagtt aggcattggt aatggaaatt ggaattgatt gatgacgtct tcttcacggt
     7021 aaccaccgag cgttgaatct gccgttaaaa tgatagcttt agcccctgct tctactgctt
     7081 tgttcaaaat gaactcattg aatctgtcgt ctttactcat atataattgg aaaaactgcg
     7141 gtgcgcctgg cgctgcatcg gctgcgtctt tgattgtcgt atttgcataa gtgctgatgg
     7201 aaaagattga tccagcagca gctactcctt tagctgtatc agcttcccct ttttcatgtg
     7261 ccaatccttg ggccgctgat ggcgcttgga taatcggtgt atctaattca attccgaaaa
     7321 cagatgtatg caaatcggct gagtcgattc cgcgtaatat ccgtggcatg attttctttg
     7381 tattaaaaga agtcgtattt tctttcatcg tccactcatc ttcagaacca ccgcgaatat
     7441 agccaaaagc tcctgcttcc atgcgctctt ttacacgacc ttctagttag gcaatgttta
     7501 caatatcgat tggatgttct tcattacttg tatgataagt catagtagat ccttctttca
     7561 tcttcttgat tacatataaa tcatactaaa cttacaaaaa gtaagcaaac atttactctc
     7621 agatactttt atcgctattc tttccaaata aatcgactta caagctgatc tacttcttgg
     7681 ttttcatgaa gcatactatg agaggcattt tcacctgtca ctactttttc ctctatttca
     7741 tttccgcgtt gcttcaacaa cgcatagacc gctaatgcac tgtttaacgg tactgttcca
     7801 tcactcaagt ctgtttcatc tagttgacca gcaatcaaga aaaatcgagt ggttatagga
     7861 atattaccga tcatttgctg gtaatcttga tagcggttag aaacgacagc aggccccttt
     7921 gctaactcat ctgtcagaga ctgcgcacta tcatcgacaa aatcattaaa aggcgcgcca
     7981 attgctgtta atgtctgaac ttgtggcaat gacgtatcct gtccatacgt tcctaaatag
     8041 cgtagtgcac taactcctcc catggaatgc cccactatgt tgactttatc tatgccgtag
     8101 ttttctttca gatacaaaag acaagttttg atccattctg cttgattcca ctcgttattt
     8161 ttattatctt caaacaatac ttggaccatc ggattgtctg cttttccaga caaatctcct
     8221 gttgcttgta tttgtccatc tgttcctact gttaaaacca attcttttac tgcttgctga
     8281 tttttttcca aacgccgcaa catcccttta aaggaatttt ctgtcccgct gtagccgtgg
     8341 aaaaaaagtg ttggaatagt ggttttttct atcactttac tggattctgc cgttttttct
     8401 ttatcagaaa cttcagtagt atttatcttc gtcgtctggc aaccacttaa cgcaaacaaa
     8461 ctgataagga ctaaagctgc tgcagttgca cgtttgcata aatttttgat tggttctgtc
     8521 atacacctct tcctttccat atagaaaaaa gaaagacttg aaaggccaat catatgatcg
     8581 acatttcaag tctctttatt aatcgatttt atctacttga tcgaaatcaa gttctgtact
     8641 ggtttcacgt ccaaacatat cgatgttgac tttcaatttt tctttttctc cgtcaacttc
     8701 tgttacttgt ccttctaatc cagcaaatgc gccttcgatg attttcacga cttcgccaac
     8761 ttctacttct agatcatttt gtcgcaggct cataccgata gaacgcaaga tatgattgac
     8821 ttcttctgga agtaatggtg ctggtttgct tccggctccg tgtgaaccaa cgaatcctgt
     8881 cacaccaggt gtgttgcgga caacatacca tgaagcgtct gtcatgatca tttcaacaag
     8941 tacgtatcct gggaatgttt tatgaacgat ttctttttct ttcccatttt tgacttcagt
     9001 ttctttttct tcaggaacaa cgacacggaa aataaagtcg gccattttca tactttgcgc
     9061 acgagattcg atatttgctt ttactttgtt ttcatatcct gaatatgtat gcaagacata
     9121 ccagtttttt tcaaaagatt ccattgaagg ctcctcattt cattgtaaaa taaaaaaacc
     9181 tcagtacacc cgaagttttt ctttcgcttc attatagcac taaaagtacg ttgtggctag
     9241 cgagttattt taaaatccag ccaaataagc tttggatggc tgtatccatt acgtaaaaca
     9301 tcaatccgaa aataatagaa gtttcgatga ctactaacgt atctttacgg agttgttttc
     9361 tgcttggcca agttacttgt ttgatttcat cttttacgct ttttagaaat ttcatgagac
     9421 aacctccctt gctactgttt atttcgtttc tttatgtaat gtatattgat tacaatattt
     9481 acaaaactta ttgatttcca aacgttcgcc gctttttcct tcactgactg attttgtgta
     9541 gttgcgagac ccacaaacgg aacaagcgag tgctgctttt ttctttgcca tttacttctg
     9601 cccccttgct gagaatcaga cttatacttc ataacagtat cacgtaactt tttacttgtc
     9661 aatttgtgaa ataaactatc tattgttttg gataaaatta tgatatgatt aatttgaaat
     9721 taagctaaaa tgagacaatt ggaggtatag cgatgctatt aaaaacactt gtatataaga
     9781 aaaaagatct gacaaccgtt acagagacta gtacattaga agaagcatta aaaattttag
     9841 aaacttccgg ataccgttgt gtgccgatct tagattcttc aggtaatatt ttccgtggaa
     9901 acatttacaa aatgcatatc tatcgtcata aagcaaatgg cggtgatatg acgcttcctg
     9961 tcactcatct tttgaaaaac gctacaaagt tcatttacct ggatacttct ttcttcaaag
    10021 tattctttac gatcaaagag cttccttata ttgctgtcct tgacagtgaa aatcattttt
    10081 atggtatttt gacacatagt acgttgctta atatgctctc tcaatcttgg agcgtagaac
    10141 aaggaagcta tgtactgaca attgcttcca caggaaagca aggagatttg gctgctattg
    10201 caaaaatcat ttcaaaacac agcagcattg ccagctgtat tactcttgat atcgaaaaag
    10261 acgaatacat tcgacgtaca ttgatcacgc taccggctaa cactgaagcg aaagtatgtg
    10321 aaacgatcgt caaccactta gagaaaaaga attataaagt ggtagaaatt gaaaatttgc
    10381 aaaaccaaga agcataatca aaaagcgaaa aaagaaaaca gctaatctgc tttctttttt
    10441 cgctttttat aattagacac gcttttcaaa atcaagcgcg cgatctaaat aatacatcaa
    10501 tggtgctgaa acagccatga cgataaactc acttaatgca agcgtgccat aggttgtcca
    10561 aaatgcttgg ccacctgttg gaactaacat ataagcaatc agtcccatgc tgatggtaaa
    10621 gaagatcgtg ttcaatacta aacgcatctt tacatttttc actttgtttt gcaataaagc
    10681 tgtcaggcct aaagaaagca atgtttggcc gccaccaaaa accacatcca tgataccaaa
    10741 accaaagaag gcattataga cgatgacccc gcctaaaact ccccaaagca atttacggtt
    10801 aaagacaact aaatgattca aactttctga aatacgaaac tggatcggcc ctgaggatac
    10861 aggcgcaact aaaatagtta acgctagata aagagccatg atgatgccat ttacaacgat
    10921 tacggataac cgttgtctgc ttttcgtttt ttgcattttc tctcctcttt tctcctagtt
    10981 tttttaacgc gggatggttg atgaaccgcg gttatgtgaa acaaacaata attataacag
    11041 acttttcatt tatttcaatc cgtcttatct gcttttaaaa aagcaaaagc ttaaacaatg
    11101 taaacgtttg ctaaaaatcg tgggatatgg tataaagtaa gtgtaagggg tcataagaat
    11161 tcccagtaaa gcagacgaag taggatctgc aagaacagaa ttgttgtgaa acttaaataa
    11221 ataaaaaagg atgtgggaat ttgagcaacc tcttactaga gaacggtcta gcaagcagct
    11281 gaagatctaa gtggacatgc cgaaccttgg aacttctcct tacgtaagta atggatcatg
    11341 cgcttgctag gcttttttgt gtttttcggt cttcggacct ttttcatttt cctagacttc
    11401 tgctataata accaagaatt aattttgtaa cagatttttt tgaaaaaaca agtttctttc
    11461 attcaaaaaa tagaaaaagc ttgctaatta ttggttaacc agcaaacagg agtattaaaa
    11521 tatcttgttt tattgaatag caggaggaaa tcatgaaatt ccattatcat atattgatca
    11581 atccatcggc aggcagcgga aatggctata aagtagcaga aagaatttta ccggtattaa
    11641 aaaataagca tattgactat acacttcatt atagtgaata caaaggacac gatgctgaga
    11701 ttgctgaaac tttggcaaaa gaaacattga ttccttggat agaagaagaa cagaaaacaa
    11761 tcgatacttt cccccttttg atcatcgtag gaggtgacgg caccttacat caggtacttg
    11821 atactttcta tcagatggaa gtagaattcc cagttgctta tattccagca ggttctggaa
    11881 atgattttgc tcgaggggca ggccttccaa aaaatcccaa aaaaggactt cagctgattt
    11941 tagcagctca atcaccagaa aaagtccaca taatggctta tgaagaaaaa ataagtgaaa
    12001 aaaaaggaat agctgttaat aatttcggta taggattaga tgcagctatc gtccatgcga
    12061 caaatcattc ttccacaaaa aagcgattga acaaatacaa cttaggatca ttttcgtatt
    12121 tattctctat tctccgtgct ttattcactc aaaaaggatt tccaattctg gtagatgcag
    12181 gaggaaaaca attaagtttt tcaaacgcat ttttatgtac agcaacgaag catccttttt
    12241 ttggcggagg aatcgcgatt gttccaactg ctgatgcgtc taaaccagtc attgattttg
    12301 tcgtggtcga acgaatcaat ttctttaaaa tcttgtggct cattctttta cttatacaga
    12361 aaaaacaatt gaaatcgaaa tatttccatc actacacaac aaacagatta cgtatcgttt
    12421 caacaacacc gcaacatggt caagaagatg gagaagaaat ggaaaaacga ccttttgata
    12481 tcacaataac cacaactaaa cagttgtttt ggtgttaata aaagaggttt tgtcagaagc
    12541 tacatctgga acaccgttta ttcggaaaaa aggactgtga cacgactttt gtcacagtcc
    12601 tttttttact atgcagttaa ttctttgccc aattgggttg ccatcgatag tttctttctt
    12661 tacccaaaat aaattggatc attgaaaaca ccgcagcaaa agcaactaag acacaaccat
    12721 tgaaccaaaa agattctgca aatgtttgat tgtaactgag tgtttcactg atcaagttat
    12781 tattttgaac aaaccaatat gttggtgtga atgccgctat tttgctaacc atttctggca
    12841 agtattctgc tggtacaaac accccaccga taaagcaact gcctgtgata aaaatatctt
    12901 tgatcccacc gctggtttct gagtttttta ccaatgaagt gatacaagcc gaaaagctaa
    12961 tgatcggcaa taaaaacaag aaagtattta aaatatgata ccataccgtt atatcccacg
    13021 aggtgtggat cactaacaga accattagaa gtaagaagcc actgaacaac agcagcgagt
    13081 aactaatcaa actaaaggtt actttgcgat tcaagtttcg tttggtaatg ggcgcactct
    13141 ggtttcgttt actgatctct ttgcgattaa acgctagatt gatgacgctg aaaccgctaa
    13201 aaatggatag aaacaaccca taagacaaga aattaaaggt tgtgcccgtc aacagctttt
    13261 tcatccgctg actatatccc gcacttagct caacttctcc agtaaccgag agtgccattt
    13321 gtgtctgttc catagctgca tcgattgttt tatcttcttc ttgaaacaga atcagtgttt
    13381 gcaaaaaggt gttcacttgc tgtgtaacaa ctgttttaga aaaggcatct gggcgactct
    13441 gtatcttgat cgtcgccatc tttcctactt cgacttgttc ggtaaagtct gcaggcagat
    13501 gtaagataat gtttacacga ttaaaataaa gagcatcatc gatttctttt tgtgaggttc
    13561 catccaatgt aacgactgtt tccttgtcat tcaaatattt acgaaggcca tcgactacag
    13621 gcgactcttc ttcactaatc aaggcgattt tcgcatcttg cagagaggta ttttcaacat
    13681 caatattttg cgcaaaaaag aatgtggcaa caacagtgat aattacacct atcagtaaat
    13741 tcgatttatt tgctttaagc aatgtccaaa tcgttttata aagcgtcata acgcacccct
    13801 ctttccatcc aagcatttcc taacgcaaaa aggaaaataa atccgatcaa ccatagaaga
    13861 ttggtataaa aactagccaa atcagtgtag aaataaagtt tatacaaact ttcgctgatc
    13921 aagttgacga gatttaattg accaacaatc ggaatatgaa gatcaatcca atacttcact
    13981 tgttccgacc ccatcatacc agcaaaaaag ctcatcgcaa tcgtcactga aatcaagatg
    14041 ctatcctttt gcaccagatt catttttggt atcaaattac caaccaatgt acctaacaaa
    14101 atcgcacaca acgaccccag agcggtaaca atcatcaacc attgccaacg ttcaccaaag
    14161 tctacttgat agataaaacg aaagacagct aacataatat aaatctctgt caaaacaatc
    14221 gtaaagcttg ctgccaaatt agcgattgaa actaacgatt gctttctagg aatcaaggac
    14281 aagcgaatac catttgacga ttgatttgct tgctgatcct gtacattgcg gaccccccac
    14341 atcgtcccgt agagaatcgc cattccaatc agagtgaaga aataaaaact tttgaaactc
    14401 atattacgac ctgcatgaac ttcttgaaaa gatacttctt gttcaaaaac agtcatgatg
    14461 ggcgcgagat caacgttctc cacttctgcc actttactcg aaattatacc aatacgctgt
    14521 aaaaattgat ccatgacgtt tttcatcaac gtctgactca ttcctgcttg acccacatgg
    14581 agcgaaacag atgaaccatc aatgagataa aaaccagcca aatcatctgc atttagcttt
    14641 tcattcgctt ctacttccga tagttcctgt acttcaaata atggtttatc attgacttcg
    14701 acttgttcta agactgtggt aaaattttcc gaaagcgctg tttgatccgc tttgattaca
    14761 attccagtat taatcgtttc aagattgcca ccttgatcaa tctcgccaaa ggccgccata
    14821 aacatcaatc ctaaaagaat tggaaaggcc aatgtccaaa acaacatgga tttatttcgc
    14881 agcagtattt ttgtgcgata tttataaaaa tgccaaaaca ttatttcccc tcctctagtc
    14941 tctcaaatcc ttgccagtaa tctctaaaaa gacatcattc aaggacgctt ctttggttgc
    15001 tatttttccg taactgatct tttcttcttg taagattgta agaatcggca acaatactgt
    15061 atttagttca gtagttgtta cttggagctg acctttttta taagcgattc catcagaagc
    15121 tattgttcgc tgaatcgctg acaacacatt ttctgggagt aatgggatgt cgatcgtcaa
    15181 acgatccgcc gtccgtacca tatcttttag agattctttg gttcctttag caatcacctg
    15241 tccttgatcc atgatcacga tctggtcgca aagaatttct acttcttcca tgtaatgtgt
    15301 tgtatagaca atggttgctc cttgtcgatt cagctccttg atactttcta aaattttatt
    15361 ccgactttgg gggtctacag ctactgtcgg ctcatctaaa aaaattaacc gcggcttgtg
    15421 ggcaatccca catgcgatgt tcaaccgacg tttcaagcca ccactaagtt ctcctggacg
    15481 aaacgaaaca tatttttcta atcccactaa ttgaatcacc tcttcaatca aggctttcct
    15541 tttctctttt tcggaaacat ataaaccgca aaaataatcg atattttctt gcacacttag
    15601 ttcgtcaaag accgcaacgt cttgaggaac gaccccaatc attgccttga cagcataatt
    15661 ttcaggagtc attgttgtcc cgaacaattt aatggttcct ttgtcataat ttaacaaaga
    15721 aagcatacag ttgatggcag tcgatttccc actgccgttt ggacctaaca gacctaagac
    15781 ttctccttct tgtacttgca gatcaaaatg attcaatgct acaaaatctc catagcgttt
    15841 gactaattta tcaatttcga taatcatcat gaaaaactcc ttccaaattt cttgttgatc
    15901 tgactataat aaagtgcaag aaaagaaact agtgacgatt ggctaaacca cacatgacat
    15961 ttgtcacaat gaaggagtct gctatgcata aatctcggct actcaacgaa actagctttc
    16021 tactggttat ctcattgctt ttgctggtaa gtcaaggatt cgttgctatg caagttatct
    16081 atttattgat cgccgtttta ttcactggtg tcagttattt actgcctaca aagccaaatt
    16141 ggattttcca agttattcta tttcttttat gtgccttttt acctgatctt gtcctgtttc
    16201 tgccagcgac gatgcgagtg atcgcccctg aagaaagcca ccttgattac ttgtttttgt
    16261 taggtttttt gttgatttcg acggttggta atcatccccc catcaaggtc gcctttgtcg
    16321 taattttgct gtttttttcc ttttacttac gaaaaaaaga tcaacgaacg accgatcttg
    16381 agaaaaagta cattgtctcc aaagatactc attgggaaaa acaacaagag ttatcggaac
    16441 aaaataaagc attggccctg tcacaagaaa cacaattagc cttgcaaatt gtggaagaac
    16501 ggaaccgaat tgcccgagac atccatgaca atgtcggtca tctgctgtca agtgcgattt
    16561 tacaaattgg tgcgcttgaa atgatcaatc aagaaccaaa actaaaagaa ccattagaaa
    16621 atttaagtgc caccgttcac actgggatgg atcggattcg tcaaagtgtc catgacctcc
    16681 atgagacatc gatctctttt caacactcct tagagtttct gatcgctgat tttccttctt
    16741 ctgttacgat tgaaggaaac ttgtttgaag gattgaatga aacgcagcaa aactgcttct
    16801 taatggtcat caaagaagcc ttaaccaaca gtatcaaaca tagtcatgcc aaaaccgttg
    16861 ttttacattt tcgaacgttg ccggcctttt atcgcttgca aatcacgaat gatggcacca
    16921 gcccacaaaa aaattctgct cccggtattg gtttgaaaac gatgcgtcaa cgtgttcaag
    16981 aacaaaaggg acaagtccat attttccaag aaaaccagca atttcagtta acgatcattt
    17041 taccaaggga gggacaccaa tgataacagt agtcattatt gatgatgatc catttgtgac
    17101 gaaatcgtta caaaccattt tagaaagcac gaaagagatc cgtgtgttag gcattggtca
    17161 ttgtgccaag gatgcgcgaa acccatcgtc ccgatgtttt gctgacggac atccgcatgc
    17221 ctaaacaaac gggcatcgat gctgccaaag aaattttggc taaatttccc aaagccatcc
    17281 ttttgctttt gacgacattc aaagatgaag aatacatccg cgaagcattt tccatcggtg
    17341 tcaaagggta tttaatcaaa cagaacttgc aagcgattat tccttctgtc aaatccgctt
    17401 ataatggaca ggccgtattt ggtaatgaaa tcatcgagac tttcactcaa atgatgaaga
    17461 ataaaccgac gattgatagt catgcttatg cttcttttag tgaacgtgag cttgcaatca
    17521 tcaaagaagt agctgccggg aaaaacaata aagaaattgc agatgccttg tacttgagtg
    17581 acggcactgt tcgcaattac atcagccaat tactagaaaa gctagattta cgggatcgca
    17641 cgcaattggc tatctatttt tatcagcatt tgcaataagt cttatctaac acaaaaaaac
    17701 ctgaatgatg ctccttcgca tcattcaggt ttttttcaca tcttctattc aattgtcccg
    17761 caaaccattt cctcacgatt gaaagaatca aggattcgca gggctgccag gattcgttgg
    17821 attgttcggc gtgttaggcg gaaaaatagg cgccttgtct aacgtttttt ctagttttga
    17881 ttcttcacga tcgtctcgtt ctacatcagg actttcattc aatttgaatt ctttttccat
    17941 ctcatctaac tttttaaagt cattgccaga ttcttttgct aatttcgcta atttatcttc
    18001 ggtttcttta gccataaagt aacgcccccc ttttgatttc agcttagcat atcacactga
    18061 aaaaacaaaa gaaaacgcta accaacgatc atttttagct atttctcatc tttaaaatca
    18121 agcatttttt gccggtataa aatcgtaggg agaactgttt tccataccaa tcatcggatc
    18181 tactaactgg ttatcgatca cttctgctgt aagaacgaaa tctttagaaa cagcaggttc
    18241 tacctcttct ttcttttctt ctccaacaaa tgaagaaaac agatctggtt ccactgtttc
    18301 cattacttgg tttttcgttt cattcgtccc actgtcatct tctacaggta gcttttcttt
    18361 tacaacccgt ggctcttttg tatagttccc atcttcaaat ggatcatttc cgaccaaaga
    18421 atcttcataa gctgctagtt tggtccggag agtgatattc attttatcat tatccatgat
    18481 ccttgatttc aacgtagtca tccggcttgc tgattcattc gctacacaag tgacataggc
    18541 ttgctcttcc cctaacaaaa tcaacagttc cttactgcga gtcactgccg tgtagagcaa
    18601 attacgctga agcatccgct gatattgatg gaccatgggc aaaataacca tcttgaattc
    18661 actgccttgt gatttatgga ttgagcaaca ataagaaaga gtgattttat tccattcgtt
    18721 tcttttataa gtgacctcat ttgcatcaaa ctggataact aattcatcca ctttatcttc
    18781 agaatctttt gccaagatga tacccgtgat ttctcccata tctccattga atacattcaa
    18841 ttcgggagta ttgactaatt ggaggacttt gtctcctatc cgataaacgg tgtcgttcca
    18901 atgtacttcc ttttttccag gtttccctgg attgaatatc tcctgcatca ttttatttaa
    18961 cgcatcgatc cctgcaggtc cccgatacat tggtgctaat acttggatat cttgtgcacg
    19021 gaatccctta tttttcgctt tttccacaat tttagagatc aagggttcaa tttgataagc
    19081 atcacttcgg aaataggaac gatctttttg attctttgtg aaatcttttg gcagacgtcc
    19141 ttctttgatc tcatgggcaa gaggaataat actagaacca tcaccttgcc gataaatctg
    19201 attgagttcc attttgggaa tttgttcgat ttccaaaaga tcatggagta cttgaccagg
    19261 accgacagag ggaagctgat ctttgtctcc tactaagata acttgcatat tcgtcggaat
    19321 cgctttgaat aatgtgttag ccagccatgt atcgaccata gacatctcat caacaatcaa
    19381 aagtccgcct tctaattctt tcgtactgac tgaaggtgtt ttttcccgtc cattcagccc
    19441 cagaagacga tggatcgtac tggcaggcag acctgtcgtt tcgttcattc gtttagctgc
    19501 tcggccagtt ggtgctgcaa gtagaatagg aaaaatttct tgggtatatt ttgaaggatc
    19561 caattccagt ccgttcaact ctgcaaaaag attgacgatt ccgttgatca cagtagtttt
    19621 ccccgtacct ggtcctcctg ttaaaataaa tagaggggaa cggattgctt cagcgatagc
    19681 ttgttcttgc gaaggtccat actgtatgcc gaatattttt tcgatacgcc gaatattctt
    19741 ctgcacttct ttttcaggat aatggatttc ttttttacga ctgagaaggc gctggatcga
    19801 attaccgatc ccccattcag aaaagtacaa actgttttcg taaagattag tctcttcttg
    19861 ttgtatcttt ccttcttcaa caagttggat aattacagta gcaacctgat caggctggat
    19921 ttcaattggg cgacttgttt ctaaaatacg gatcgtttgc tgaagcaatg tctccgccgg
    19981 tacgtatgta tctcctgttt gaactgcatg ctgaaaaatc tgatgcaaga tagctgctcg
    20041 aattcttctc ggtgaatctg ctgcaatacc gatttgttcg gctagattat ctgcacgttt
    20101 gaacccgatt ccttctatgt cttcgactag ctggtacgga ttttcttcga tgatatccaa
    20161 agactcgttc ttataggcct ggtagatact gaaagctaac tgactaccga acccgtaacg
    20221 attcagtccc atgatcactt gatccatccc gtggtttagc cgaatcgtct cagcaagcat
    20281 ttctcttttt ggcttcgtca aaccggagat ttgttttaat accgaaggat cagcaatgat
    20341 tttttcgata gcatcttctc ccagcaattc tacaattttt tctgctgttt tcttcccgat
    20401 tcctgggaat ttttcgctgg aaagatacgc tacgatccca tttgcagttg ttggcttttc
    20461 ttgctcatat ctttcgagtt taagctgcct tccgtattta ggatgatcca ctaattctcc
    20521 ataaaaacga taagtctcat tttcttgaat atcgccgaaa cttccggtga ctacaatctc
    20581 tttttcacgg taatcagctg tggtttcact gatgtgtacc aaaagcactt tgtaaaaatt
    20641 actaggattt tgaaaaaaaa tcgcggcaac tgtaccaacg aaataaggca tttcttctgg
    20701 ctgcatcgga agccgcctcc ttcttctata gtaaaggttc tggtgctgtt tcagttccta
    20761 aaaaatctgt ttggttccat actttcagtt catatggcaa taatctgcaa ggctcttcag
    20821 tctctaaaat cgtcaaacta ctattgaaca atccacccat ttcacgcaac tcacttagct
    20881 cttttcctgt catccattga atggctgcag ttaaagaagc tccatgtcct acgaataaaa
    20941 gtgggccatc tttatgtcgg gcaaccgcat ctgctacaac agtttcgata cgtgtgattg
    21001 ccgattcaat cgtttctccg tgaaaaggag aaggatcata cagatctaaa tgattacgca
    21061 aattcggcag attatccgga tatttctggt acatttcatc gatcgactga ccttctaaag
    21121 tacccagccc tagttctctt agcttatctg tataaaaaat ctctaccgga cgagcaagct
    21181 ctttgttgat accttctgct gtatcacgtg ctcgctttgc tgtactggaa taaattgctt
    21241 taaaaggaac atattttacc tttttcccaa atgctttgat ttcttcgtaa ctttgtggca
    21301 aaagcggaga atcgccattg ctcccttgaa aacgtctttc ctgattccat tgtgtcttcc
    21361 catgtcgggt aaaatatagt tccatacgca gcaaactcct gtctttcttt tattttactc
    21421 tataataaac tgtctaatcc agcttgtcat tttcatagtg atgcgtcaat tctaaattag
    21481 ggaatccttg ctggcgaagt gcttcataca ctatcattgc agctgtattc gataaattca
    21541 atgagcggac atgctcatca ttcataggga tgcgtaaaca cttttcttcg ttttcacgca
    21601 taaatgtttc tggcaaaccg gttgtttctt ttccaaataa aaagaagtgc tcttctccat
    21661 cagcaaaatt ttcgtcacta tatactttat gggcaaattt tgagatcaaa tgtagtttac
    21721 gattacctaa aaatgttaaa aaagcttcta aattactgtg gtaagtaata tttacatcat
    21781 tccaataatc caaccctgcc cgttttagat gtttgtcatc agttgaaaaa cctagtggct
    21841 cgattaaatg aagcggagta ttcgtggctg cacacgtacg ggcaatattt ccagtgtttg
    21901 cagggattaa tggttcaaat aaaacgatat gattcatcag gatcattcct ctcatattta
    21961 tgttcgtttc tattttctga caatttgatt tttgcataaa aaaaaacgta tcaactcggt
    22021 gtcagtcact gcgagtcgtt acgttagtga agctcttctc actaactttt atcagaacag
    22081 gaacctgata aaaaccaatg aaaaaacaac ttgttgctaa tataacaccc tcaacttttt
    22141 tttgcaacct ctactcatta aaaactgcta gaaaaacgtt ttctcttagt tccttttaat
    22201 aattctatgt caattgtaat cttcttcaaa ggattcttat ataagtctgc tttgattcgc
    22261 tcttctacct gccattctaa aggtgacatg gccaaaagat ctttttgatt ttcctctggt
    22321 atctcaaatt cataggttac acgctgacgt tcagttaatt tcattgcttc agcaaacttg
    22381 gctactacac gttcattgga ataactctgt ttttcaggtt gattcggata aaaagcctga
    22441 cgtagttcct ttaaataatt ttcttgtggc accaccttca acacttctcc atcttctgag
    22501 agtacacgtt ggaattcttg gtaatgagaa ggcgaaaaga tatttaaaac cgcgttgaat
    22561 gtttgatcag caaacggcaa attggtcaaa tcagctacac accaaaatgc ttcggcagat
    22621 tgttctgtag ctgcgtagac tccttctttt gaaatatcaa atccaacagc attttgaatc
    22681 tttttcaatt ttgaaagttc attcaagaag ctaccttctc cgcagccaac atctaatagc
    22741 gagacttctt caggtaaatg ctgcgcaata gtctcaataa cgggctgata catgccagat
    22801 tggatcattc tacgccttgg aacgaacatt ccttgatcgt attctgtttt aaccgcatgg
    22861 gataaaaaat aaagtgttcc ttttttggaa aggtcaaaac ggtgattatt tttgcatatc
    22921 aagccattat cagacttttt tacttcttct tggcaaaccg gacagcggaa cagctgatga
    22981 ttttctgcca aaaactggcg tcctcggtca atttttttta acatagttcc ccctcatttc
    23041 tgttttatct taccgttaga tgctcacttt ggcaactgct aaaaatatga tacaatgcct
    23101 agaagaaagt gaaagataaa ggagaagatt agatgatcaa agaattttgc gctgaaaact
    23161 acacatctat tcctctagca attgctagag gagccgatcg gatcgaattg tgtgacaact
    23221 tagcggtcgg tggcacaacc ccgagtactg gtgtgatcga agaaacgtta agttatgctg
    23281 gggaaaaaga tatccccgta atgacgatta ttcgtcctag agggggcgac ttcgtctata
    23341 acgatatcga attgaaaatc atgcatactg atttgattga agcaaagaaa ttagggacgg
    23401 atggcgtagt atttggttgt cttactcctt caggctggct agacgaagag gccttagaac
    23461 tattgatcga aacagcagaa gggttgcaga tcaccttcca tatggctttt gacagtattc
    23521 ctgaagatcg gcaattcgaa gcaatcgatt ggctggtaga acatggtgtt gaccgtatct
    23581 tgactcatgg cggtcctgct gacaaaacta ttgtagaaaa tttcccacgg cttaaagaat
    23641 tgattgccta tacagatggc cgcttaatca ttttgcctgg tggtggtgtc actgcagaga
    23701 atgcagcaca tgtagctaaa gaattgaacg taagcgaagt acacggaacc aaaatcgtgg
    23761 atcttcagtt ataatcttat aaacaaaaaa acatttgcaa caggcataat gcttattgca
    23821 aatgtttttg tttttttaca taaaatagcc cataaataaa gaagcaatat tgaaataaat
    23881 cagtacactc gtcaaatcgc tcaaagtcgt gataaaggga ccgcttgcta ctgctggatc
    23941 aaatcctaga cgatccatta gcatcgggat taaactacct gcaagattcg ccactgtgat
    24001 tgcaaatagc atagccatcc ctatgacaaa ccccaagata aaattatgtt tccaaaaacc
    24061 tacgattaga aaaatcgtga tccccgtaac agctcctgtg acaacgccgg tcaagacttc
    24121 agccaaaaca agtcgaacaa atccatgatc tttctcatca gaaatcgcaa gtcgacgaac
    24181 agccacagct agcgactggg ttccagcatt accggcagtt cctgtaatca gcgaaatgaa
    24241 gactgctaaa atactcgctt cacttaccaa gtcttcatag tgactgatta aagaagcggt
    24301 cgacatacct aaaaacaaca gagtgatcag ccaaggcaaa cgtcgagacg ctgcctttac
    24361 tggattttca ttaatttctt ccacattgac cccggcaagt cctgaataat cgctagcagc
    24421 ttcatcatca ataacgtcga tgatatcatc gactgtgacg attcctaaca aatgatcatc
    24481 ataatcggta acaggaagag ctaagaagtc ataatctcta aatgtttgtg ccacatcttc
    24541 ttggtcgtcg cctacatgaa ctgaaagcac tcgttcgctc atcagatcag aaatcattgc
    24601 gtcgtcatca ttcacgatta ggtcgcgcag agaaataacc cctactagct gaccttcttg
    24661 attaacgaca tagatgtaat agattgtttc agctacatct gcttcgttct tcagcacgta
    24721 catcgcagag cgaacagttt gattggctac gatcgaaaca aattcagttg tcatgatcgc
    24781 gccagccgtt tcatcctcgt aatggagaag ttccttgatt tcactggcat cgtctgccga
    24841 catcaaactt aaatatttag caatttgctt tttatccagc gtattaagca agtcaacagc
    24901 attatctgta tacatctcag aaagcatatc agctgcatag ctaggacgca tttcatctag
    24961 gtattctttc atatgttcgt tgtcttcttc aatcacatcg aacatatccg ctaattcttt
    25021 aggcgacaga taggaataga tcagctgcct gttctcttct gtaagagatt ggtagaattg
    25081 cccctgctca tagatatgca tctctaaaaa actgtttctg aatgcctgaa tattattttc
    25141 ccttaaatct tgagtcaact gggcaaatct ttcctctaat tcttgatttt catccaaacc
    25201 aatctcacct cgccttattc ttcaaaccgt ctcacaactg cctccatgtc tgcggctaaa
    25261 ggctgcttga actccagcaa ctcttctgta aatggatggt aaaaacgcag atcataacaa
    25321 tgaagggctt gtctttttat tcccagatcc attcgcccgc catacatatc atcaccgagc
    25381 agggcacagc caattgcgga aaaatgaact cttatttgat gtgtccttcc tgtatgcagc
    25441 tggatatcaa ctaacgcgat ttctgttagt cgcttctcta tccagtactc agtctgtgcc
    25501 gaacgtcctt catcagagac cattcgcttc aatagcgaag aataatctcg ggcgatcggc
    25561 aaatcgatat gtccatgtgc cgataaatct gaaagccttc cactgactaa ggcctgatat
    25621 tttttcacaa acttcttttc acgaagttgc atatctaatt ttgcgtgcgc aaatccatgc
    25681 tttgcaaaaa gcatcaagcc agatgtatcc cgatctagtc gcgtcaccac atggattact
    25741 tggttttcgt aaccttgttt tttataataa gcctttacac gattagccat tgtcccattt
    25801 ggatggtatt gggcaggaat agacgaaacg cctgctggtt tatttactac cagaacgtgt
    25861 tcatcttcat acacgatatc gatcggtgtt tcatccaaaa gtacggtttc atgttctcct
    25921 tcagcaggaa tcacaatggt taccttatca tccttagcta gagaaaacaa gacattttct
    25981 acttgatcat taactttgat ttgaccgcct tgaaatttta ttttcgctaa cagacccttt
    26041 gagatccctt tttcttttaa aaaatatttt acttgctgag aatgatcttt ctcataatcc
    26101 catgtaaact gcatatcaat cctcactaat aaaggcatct ttcacacgat gccaaaaatg
    26161 catatgtcga taagaagcaa aatggatccg ttcttctgct attcgataat aaattgagcg
    26221 gatatttgct tttgcgacat tcaattgatc aaccgttaca agataatctt ctgtattttc
    26281 caattttatt tctagccatt catcatgggc aatcacgatc ggagaaccca aagtacgaaa
    26341 cactcgatta ttcagtgaag caatctctgc caactgaaag gcattgatac taggatggat
    26401 cacagcaccg ccgacacttt tattatatgc tgtcgaacca gtaggcgtag aaatcgtcaa
    26461 tccatctcct ctaaaacttt caaacagctc gtttttgatg tatacatcgg ctaccatcgt
    26521 acgattggcc cgtttaatcg ttgattcatt cagtgctaaa aaatgctggt ccggtgtttc
    26581 atccaaataa ctgatccgaa catccagcaa gggataacta acactttgtt cccggttcgt
    26641 tcgtaagctg tctactagtt cttccagctc gtaatcccgc caatccgtgt aaaaccctaa
    26701 atgacctgta tgcacgccca agaaacgcac atcattcaga caatgactgt agtgatggaa
    26761 cgccgacaat aatgtgccgt ctccgccgac tgagatgacc aattctggct catgatcatc
    26821 tcgttgaatc cctgcttgtt ctaaaagtgc gttcaaacgt tctgtcactt ctatagtctt
    26881 tgcttcttta ttatgaacga tcgctacttt catcccctgc ctcctctctt tcgctttctt
    26941 tcttcaaaag cgttcgatag tagacatcat ctgattttcc tcttccatgg gagaataacc
    27001 gctgtgcttc ttggatttct tcacggatac tggacatctc ttcatccaac tgataggcag
    27061 cttctgccgc acgctgaagt cgttcactca tttcttctgg aaaaacgcct tgatatttat
    27121 aattcagcga atgctcaatc gttgcccaga aattcatcgc aagagtccga atctggattt
    27181 ccgccaaaat tttcttctca ccgctgatca gctgtacagg atactcgatc accagatgat
    27241 aagaacggta gccacttgct tttttatttg tgatgtaatc tcgttcttgg agaactttca
    27301 tgtcttttct tttacggatg atctcaacaa cttgatggat atcttctaca aactgacaca
    27361 tgatccttaa cccggcaata tcagacattt cttcttctaa acgtcccatt ggaatatgcc
    27421 gtaattgtga ttttgttaca atactatcga ctggcttgac tctcccagtg acaaattcaa
    27481 tcgggacatg tcgattttgt tcacggaact gtttgcggat cccccgcagt ttcactttca
    27541 attctgatac agtttgttca tatggtgcta aaaatgcttc ccaatctcgt tccatagctg
    27601 atacctctac ttcattaaca ttcattgttt attctaccat atatgcaaag ttttttcgta
    27661 ctcttgattt atgcattgac caaaaaaaga aaattaggca aaatagacaa aaaggagtcg
    27721 atcaaatgac acaaatgctt gaaatcgaat ataaatctat gctgacaaag caagagtacg
    27781 agatattcat cgctcactat caattaacag ataaagattt ccgtgtacag actaatattt
    27841 atttcgatac cgttgatgaa cagctgaaga aacaaaattg tggcctacgg atccgtttcg
    27901 ttggtcatca agctgaatat acattaaaaa cacctgctga aaaagggcgt ctcgaaacaa
    27961 cggatacctt tataacagaa gaagcagaag catttatctt cgaaaaacgt ctgcctcgtt
    28021 caggcgcagt ttttcaaaaa ctttctgatt tgaatatcga tcctgcttca ttaatccaaa
    28081 ccggaaagct tacaacaaaa cgagctgaat tccctattga agaaggactt ttagctattg
    28141 atgaaagctg gggagacaat ctacacgatt ttgaactgga actagaggta ggggatgcat
    28201 ctgtgggaaa aattgctttt ataaattttt taaaacgttt ttctttacct tatcgtcctg
    28261 ctaagaacaa gatccaacgt atgcttgaag ctaaaaatta gaaacctttc attttcacaa
    28321 ggcacttgag ttcatttttt tacttttttc tgttaagtta taggatgtga aagaatctag
    28381 tcactagttg tatagaatct attttggggg agattcatat gatcgaaatc tatttatttg
    28441 ttaatccttt aggggaatac tgtttcgaaa tggaacaaca gttattacaa tttatcgaag
    28501 aagagtacgg gacaccatca aaagaaaaga tgcaatttcg ctttcttcct ttggtcaatt
    28561 tgcagacaat tggggatgtc atgcaacaaa aaggaatttc tcagaacaat cttgaggaac
    28621 gtaatcactt attctcaatg acttattctg cagcattgga ctgcaaagcg gcgcagtttc
    28681 aaggaaagaa aaaaggccgc cgttttttga tcaaattgca agaagcagtc ggctgtaatg
    28741 acataccata ttctcaagaa cttgctgaat ccatatttga agaaatcggc ggcgatttga
    28801 atatgtttaa agaagatcgt cagtctgact tcgttaaaga agtattcttt tctgatcaaa
    28861 aaattgctcg ggaaatgggc atcacaaaac acccttctgc agtcgtttac aattatgcct
    28921 gcgaccgtga ttttggtgtt ttagtagaag taaaaggtac aagtagcctt tggagaatca
    28981 cagagctgtg taaaacaaca gataactcat atcaagtttt taatggtgaa catttacata
    29041 caaatgattc tcagttccat tcaagaacta gccatttaca cttgctttct aattaa
//
LOCUS       DAMEEU010000031        28082 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.032, whole genome shotgun sequence.
ACCESSION   DAMEEU010000031 DAMEEU010000000
VERSION     DAMEEU010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 28082)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28082)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28082
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.032"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..208)
                     /locus_tag="PB779_001368"
     CDS             complement(<1..208)
                     /locus_tag="PB779_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738900.1"
                     /translation="MLLLIGLILLIIGITKLSKANTIKKEAYELEQKNDEKLNKLHDR
                     ERFILSKEETLSDLNKQITMLKNDI"
     gene            complement(299..751)
                     /locus_tag="PB779_001369"
     CDS             complement(299..751)
                     /locus_tag="PB779_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDE0738901.1"
                     /translation="MHLNKYWILEEIEKLFVEFGSDAINPYKIIKYSDIDLIETDLGN
                     KTLGQTIHNKRCYVILINQNLSPSMKRFVLWHEIAHVRLHKGICTAAFRANNLSCMIY
                     GIEAEANMFAIEMLTRTIDEQDLSDMSQFQIIEYLGLPHNLEHLVLQH"
     gene            complement(764..1174)
                     /locus_tag="PB779_001370"
     CDS             complement(764..1174)
                     /locus_tag="PB779_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0738902.1"
                     /translation="MLLDRIKILLKERSMTLAELERKLNFGNGSMSRWNKSTPSGDKI
                     QKVADYFNVSTDYLLGRTDKRHYYDLTEKDKQDIALQAEKLLEGLNSDAETNYYGEPL
                     DDEDKEKLYDAIQLALALTKVKAKKKFTPKKYRQ"
     gene            1449..1661
                     /locus_tag="PB779_001371"
     CDS             1449..1661
                     /locus_tag="PB779_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0738903.1"
                     /translation="MTLKQQVLIALVKKGWSQRELARRMGISITYLRDIFIEKRKPKE
                     RLKQIEELLDIKLEVDSNDQPSEQEA"
     gene            1664..1876
                     /locus_tag="PB779_001372"
     CDS             1664..1876
                     /locus_tag="PB779_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738904.1"
                     /translation="MVQRLSKAEFKEKYKYSESTYQRRMKEFKKSRFSEGYNAVTSKE
                     ITIDVDLYEQFRTWRSKNRFRVRAVC"
     gene            2016..2171
                     /locus_tag="PB779_001373"
     CDS             2016..2171
                     /locus_tag="PB779_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738905.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGKKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(2168..2392)
                     /locus_tag="PB779_001374"
     CDS             complement(2168..2392)
                     /locus_tag="PB779_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDE0738906.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            2470..2658
                     /locus_tag="PB779_001375"
     CDS             2470..2658
                     /locus_tag="PB779_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738907.1"
                     /translation="MAYTLQQEHQILGLIKQRRKQLQDDRAALRKADELSDRQAELIA
                     SELEDLRMLEIKNREIRL"
     gene            2984..3319
                     /locus_tag="PB779_001376"
     CDS             2984..3319
                     /locus_tag="PB779_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738908.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            3552..4493
                     /locus_tag="PB779_001377"
     CDS             3552..4493
                     /locus_tag="PB779_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HDE0738909.1"
                     /translation="MSKSTLEMSHQEWLEDRKKGIGGSDVGTILGLNKWKSPYQLWLE
                     KTGQVVLEESGSEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPIIDGSQATADFLKEKYADVEDVQTT
                     LPIHFDELVEQKNELKRTKKEIESAIRQVDNEIISELGKREASIGITQKNIISWKFVR
                     TRRMNSKKLAEKYPDVANDEEIYNVTESRRLTEREIK"
     gene            4495..5385
                     /locus_tag="PB779_001378"
     CDS             4495..5385
                     /locus_tag="PB779_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HDE0738910.1"
                     /translation="MATNESLKNQLAAKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            5428..6228
                     /locus_tag="PB779_001379"
     CDS             5428..6228
                     /locus_tag="PB779_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HDE0738911.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWNLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADDIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            6243..7094
                     /locus_tag="PB779_001380"
     CDS             6243..7094
                     /locus_tag="PB779_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDE0738912.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGAIA"
     gene            7295..7756
                     /locus_tag="PB779_001381"
     CDS             7295..7756
                     /locus_tag="PB779_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDE0738913.1"
                     /translation="MPKILDACCGSRLFWFDKNNSDVTFMDCRQQYEELSTGHVINVD
                     PDVVADFRDMPFEDDVFDMVVFDPPHLRHVGENSWLAKKYGKLDELWPEDIRQGFAEC
                     MRVLRPSGTLIFKWNEEQIPLSDVLEAIGEQPLFGNKRSKTHWLVFMKKFS"
     gene            7782..8234
                     /locus_tag="PB779_001382"
     CDS             7782..8234
                     /locus_tag="PB779_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738914.1"
                     /translation="MKIVLNKCFGGFGLSHEAKMEIFKRKNIEVFPYINNFSYDSDDE
                     YTRYTGQKLGSMDFIYYFKKDPKIDKVTGIYSEIDRLYGIADDSSFSSDSNRGDKDLV
                     AVVEKLGSEASGPYASLKVVDIPDGAEWEISDYDGVETAHYGFQTGSI"
     gene            8340..8534
                     /locus_tag="PB779_001383"
     CDS             8340..8534
                     /locus_tag="PB779_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738915.1"
                     /translation="MDASEVVNKINSLKEVFGDVEVVINAQGYDNEFFKQITDISIQQ
                     GMEDEDGNFIDEVAILVTCE"
     gene            8565..8858
                     /locus_tag="PB779_001384"
     CDS             8565..8858
                     /locus_tag="PB779_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738916.1"
                     /translation="MKLKDGFYSSGHGIGGLMLDMPTKNPKTRKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVVRLVDMEVIKS"
     gene            8888..9328
                     /locus_tag="PB779_001385"
     CDS             8888..9328
                     /locus_tag="PB779_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDE0738917.1"
                     /translation="MSVIPQLEGEEAIVNILENIDIKQTRKNARRLLKRYRNLERLVG
                     PVKIDFSVMTVTKNLKFTIDSQNEEIIEAISTRDSVIEALTRLSRIHFQVLYYSYCFP
                     NKMSMYQIGEKLGYSDRTIERMKAVALVEFAEAYKSGELISRTK"
     gene            9403..9870
                     /locus_tag="PB779_001386"
     CDS             9403..9870
                     /locus_tag="PB779_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArpU family transcriptional regulator"
                     /protein_id="HDE0738918.1"
                     /translation="MVLFDVKKYETPSAKDVDMERTKHNVAVFLSAYLSARCRVGQHR
                     EPKVTASYSLVPPSTADHIFEAERMLIDKEEAQEEFEYLHKLFVRGYSAIQHPHKPDV
                     TERRKKIFYDRYINGLPIYVTAQRNNTSEESVKVESNRIIIQFASSLELVAFK"
     gene            10617..10847
                     /locus_tag="PB779_001387"
     CDS             10617..10847
                     /locus_tag="PB779_001387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738919.1"
                     /translation="MRNYWYVSLTNEYPRTIDDCSVRVVRSVQIKGKYSIVEMGREAE
                     PCEIDACKLVYCGHGFYDEPNIQNNINKNLRD"
     gene            11006..11839
                     /locus_tag="PB779_001388"
     CDS             11006..11839
                     /locus_tag="PB779_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small subunit of terminase"
                     /protein_id="HDE0738920.1"
                     /translation="MARQRDPRRDEAKRIWLESNGEKQLKEIASELNVSDSQVRKWKS
                     QDKWSAELISNVTNGKSNVTNQGGAPIGNQNAKGNKGNSRASPPVGNKNALKTGEYET
                     IFFDTLTDNEKDIYSSLNDDPSFALSEEIRLLKIRQLRMMKRIQQAEAGLNDEEVERL
                     QQLRKIKTPIEKNGKKLEIKREVMQDVQISRKKHRKIDDILSIEDSLTRISNQLAKAI
                     KQMNELYMNEYRTDLIKAQTDKIQAETNEIGGNNSGEEIEEWKQAVLNAANKRAVKEN
                     E"
     gene            11832..13247
                     /locus_tag="PB779_001389"
     CDS             11832..13247
                     /locus_tag="PB779_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDE0738921.1"
                     /translation="MNNEFIPFADIGSAIDYYYDKPVAFCQDILHLNPDEWQENVLND
                     LAEFSKVSVRSGQGVGKTALEAGAILWFLTCRPYAKVIATAPTMKQLYDVLWAEVAKW
                     LNDSLIKNLLKWTKTKIYMVGDSERWFATARTATKPESMQGFHEDHMLIVVDEASGVS
                     DPIMEAILGTLSGFDNKLLMCGNPNNIEGVFYDSHNSDRDKYRVHKVSSYDSKRTNKD
                     NIEMILKKYGKESDVARVRIFGEFPKGALDSFISLETVELATEKQISDSLVNKTKVAH
                     IGVDVARYGDDSTILFPRIATRALEYEKYSKRSTMETTGYVINMAKNLMSQYPSIDKV
                     MIKVDDTGVGGGVTDRLEELIEDKHYPFEVFGVNNGSTSEDDFYDNLGTQLWGNIKEM
                     LEENMTANLNGEQPVIELPSDSSLIKELSTRKFKMTSRSRIRLESKDDMKKRNIGSPD
                     IADALALAFYEPPSHYQFIQF"
     gene            13259..14788
                     /locus_tag="PB779_001390"
     CDS             13259..14788
                     /locus_tag="PB779_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDE0738922.1"
                     /translation="MISTVLSLERYKKLRVKYATQIEDGMFDPNGFIEDMKPFFADRE
                     RKYLAYTSEKNEIDNRPKPNTDIVKVNNKLHAGMYSIVVDQAVNHFTGIPIKWDYDVS
                     EQKRTLIQRLKDKFLKNDIELPTVPEAFNKLTSNLDSMRFAMLDSETATFQGACGVAF
                     RLLEPVEEDDGWKLRASNIEPWRAERYGNAGIYIKEKYDSYQKKFFQEMKVMTRNKIL
                     TYACYGDLNFVTSGTFKKIDETDNPLGTITLAEFKNNTNRYCDFEVAEEIGDAIDRAL
                     SDQQNEIEQFKLAYMLVTGTTMSKGTAKEMMNQLGIINLKAPTAKAEYVTKNLAKDFN
                     EYHMDLLKKQFYTICKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAETIAAFLKFHDKVEIEPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMMELESGSAYPDSEYNFGGGGNSDDRNEVLDQTSRTGGSSKAQTRKSD
                     T"
     gene            14706..15758
                     /locus_tag="PB779_001391"
     CDS             14706..15758
                     /locus_tag="PB779_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HDE0738923.1"
                     /translation="MTIETKYWTKRRELEDQARLKQENQTLKKLTSVFPEALKEIQAK
                     LLSQADLHNITYPEMMEFYSTSNQKKYREYVEKNYKSLKMYDAKYKEFIDEFFPPFDY
                     AKVNRLLQIRSDVFKILAEYAMDADVNQYFSDRLEEILQRTYSSNANVFVQLLNVDIP
                     NYLPENEIKHYLNYPWSGKTFSRRLWGNISSLEQKLSNAIVKSVASGEGVIHALNTMR
                     LDSEICDMFKLEESKYNKAIENLVRTEYAKFAQDGIEKSYLETGIEEYNVLTAKDERV
                     CRICGGKASKNPYKLKDAVIGENRAPFHSRCRCTDVPNLPKLGKDIDEEYDRLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            15760..16077
                     /locus_tag="PB779_001392"
     CDS             15760..16077
                     /locus_tag="PB779_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738924.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYEKMGCIVVRTDYKEGK
                     SSN"
     gene            16204..16827
                     /locus_tag="PB779_001393"
     CDS             16204..16827
                     /locus_tag="PB779_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HDE0738925.1"
                     /translation="MSMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            16842..17732
                     /locus_tag="PB779_001394"
     CDS             16842..17732
                     /locus_tag="PB779_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HDE0738926.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            17755..17970
                     /locus_tag="PB779_001395"
     CDS             17755..17970
                     /locus_tag="PB779_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738927.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            17982..18323
                     /locus_tag="PB779_001396"
     CDS             17982..18323
                     /locus_tag="PB779_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738928.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            18323..18694
                     /locus_tag="PB779_001397"
     CDS             18323..18694
                     /locus_tag="PB779_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738929.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            18687..19082
                     /locus_tag="PB779_001398"
     CDS             18687..19082
                     /locus_tag="PB779_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDE0738930.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGEVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            19084..19461
                     /locus_tag="PB779_001399"
     CDS             19084..19461
                     /locus_tag="PB779_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738931.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNNPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            19462..20070
                     /locus_tag="PB779_001400"
     CDS             19462..20070
                     /locus_tag="PB779_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0738932.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            20070..20414
                     /locus_tag="PB779_001401"
     CDS             20070..20414
                     /locus_tag="PB779_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738933.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKSK"
     gene            20380..20613
                     /locus_tag="PB779_001402"
     CDS             20380..20613
                     /locus_tag="PB779_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738934.1"
                     /translation="MKLIQRRKKVSEALKSPSFKYSITYRELDIKTQLLEAGWTLPEI
                     ERTDLDELMRLFAFRDAVKEHEDVEYYDNFTQF"
     gene            20652..23237
                     /locus_tag="PB779_001403"
                     /pseudo
     CDS             20652..23237
                     /locus_tag="PB779_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
     gene            23326..23838
                     /locus_tag="PB779_001404"
     CDS             23326..23838
                     /locus_tag="PB779_001404"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0738935.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLY
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            23835..24872
                     /locus_tag="PB779_001405"
     CDS             23835..24872
                     /locus_tag="PB779_001405"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDE0738936.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
     gene            25212..25952
                     /locus_tag="PB779_001406"
     CDS             25212..25952
                     /locus_tag="PB779_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0738937.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKGYYKNVTRKIECYYKAPSIDMVQEWEDRITEWLDMSSYSDFILYYDEQYIYQ
                     AVVIEGPEFKGTRKTGNIVPFEFTVSIRPFKENYNGRFTIRQTETFEIYNPEKYSSKP
                     LIKLSGSGDASFYINKDKYDLKSLDRELFIDSKLEEAYRKLDGNLEHQDQVTLFLDFP
                     FLYPGKNEIKWTKNIHSFEIMPRWWRKV"
     gene            25949..>28082
                     /locus_tag="PB779_001407"
     CDS             25949..>28082
                     /locus_tag="PB779_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0738938.1"
                     /translation="MKPRIYSPTETDFSTNGLGILKDCTRCGIYEVANGKYELELDYP
                     LGTRFDEYFENDYQIKAKPNDQEEYHIFFIDDKDIDTFLNTVTIYAQSRTNRLGRRVV
                     TLVEVDSKTGQEAISIIETKMDKKSDIRLYSDITAVSSTIFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRNNVGTIRYGKDMSGLKVKLDWTGIKTRIIPYADPQS
                     EVGTTNRIYGSPVDSAYINNYPDVYTEHVQFTEEQGVKDIKSLNKIAKNYFKTINPGC
                     DKPKVSITVEFDKLTDSEEAKEFAKIRNYGLFDTFKIYHKKYNIYLESKVSGLQYDSL
                     SEKTLKLEAGDIQVAFYQQQAVTIQDKLKDYATNNYMSDFNDYVSSMITGQGSAGGYV
                     VLWPKEKPSNIFIMDNPDLEKAREVLRMNKNGIAFSKKGWRGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSKGSIGTI
                     GTTDSVGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVKGKEIIPGQGGGPSGGGESTGGYPSELKTDAEKRAWRIYDILCNNGFTK
                     QSACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLF
                     NAAGIKEPITSLDAQVRLLIWTFTNGQWM"
BASE COUNT        10108 a         4112 c         5722 g         8140 t
ORIGIN      
        1 taatatcatt ttttaacata gtaatttgtt tatttaaatc tgatagtgtt tcttccttac
       61 ttaatataaa tctttctcta tcatgtaatt tatttagttt ttcatcattt ttttgttcta
      121 attcataagc ttcttttttt attgtgttag ctttcgacag tttagtgatt cctataatta
      181 ataaaataag tccaatcaat aataacattc aaaactcctc atttctttga tataattatt
      241 gtagagttta ctcagaaatg aggaaagagt ccatgtgaaa gcatgggctt ttttattttt
      301 aatgttgtaa tactaaatgt tcaagattat gaggaagccc taaatattca ataatttgga
      361 actgactcat atcagataaa tcttgttcat ctattgttct agttaacatt tcaattgcaa
      421 acatattagc ttcagcttct ataccataaa tcatacaact aaggttgttt gctctaaaag
      481 ctgctgtgca aataccttta tggagtctaa cgtgggctat ttcatgccat aatacaaatc
      541 ttttcataga aggtgatagg ttttgattaa ttaatatcac ataacatctt ttattgtgta
      601 tcgtttgtcc taatgtttta ttccctaaat cagtttcaat taaatctata tcagaatatt
      661 tgattatttt atatggatta atcgcatcag atccaaactc tacaaataat ttttctattt
      721 cttctaatat ccagtatttg tttaaatgca taccaaagcc cacctattga cgatattttt
      781 taggagtgaa ttttttcttt gctttaactt tggttaaggc aagtgcaagt tgaatggcat
      841 cgtataattt ttccttatct tcatcgtcta aaggttcacc ataataattt gtttcagcat
      901 ctgaattcaa gccttcaagt aatttttcag cttgtaaagc aatatcttgt ttatcttttt
      961 ctgttaaatc ataataatgg cgtttatcag tacgtcctaa aagataatca gttgatacat
     1021 taaagtaatc tgcaactttt tgtattttat ctccagatgg agtactttta ttccatctag
     1081 acatgcttcc atttccgaaa tttaactttc tttcaagttc tgccaacgtc attgaacgtt
     1141 cttttaataa gatttttata cggtctaata gcataggata tgcattcctt tcaaaatacc
     1201 gacaaaaaaa gtatttttct gcaaattatc tatttacaaa tagagaattt gcagttatac
     1261 tagttttgta agcaagatat ttacggcata caaagactaa aagcaataaa ctaatagtct
     1321 ccccagacat cagtaagctc gctttttgtg cgctgtattt tgtatgctta cataatagca
     1381 tatttgcagt ttttgtcaaa cttattagac aaaaatatta gaaaatattc gataaggggg
     1441 tatgaagcat gactttaaaa cagcaagtat taattgcttt agtaaagaaa ggttggagtc
     1501 aaagagagtt agctcgacga atgggtatat caattactta tttacgagat atcttcatcg
     1561 aaaaaagaaa acctaaggaa cgtttaaaac aaatcgaaga acttttggat atcaagttag
     1621 aagtagattc taatgatcag ccatcagaac aggaggcgta aaaatggtac aacgtttgag
     1681 caaagcggag tttaaagaga aatataagta ttctgaaagt acttatcaaa gaagaatgaa
     1741 ggaatttaaa aaatcacgtt ttagtgaggg gtataacgca gttacttcca aagaaataac
     1801 aattgatgtc gatttatatg aacagtttag aacatggcgt tctaaaaatc gatttagagt
     1861 tagagctgtt tgttaatagc taaaaaatct aaattcacca cttctgaaaa gaggagttgc
     1921 tgctctcctt tcaagtttgc caaagtccac gttttttcat tttggcaact cctcttcttg
     1981 gaggtggtga cggcgagaga cgaaggaggg atgacatgaa ggaagaatca aaaataggga
     2041 ttttgaatga gaacaattac acaagattaa ttattgaaac agaagaaggg aaaaaagtag
     2101 cagaagttac attgaccgat gcaactcctg ctgacggtta tcgtattcga ttaactccta
     2161 aatatgatta accttttggt gggtgtggat cgtttccgtg actatcacgg ctttgaattt
     2221 ttccatctct gccatgaata aatagctcag atccttgatt tttagaaatc tctctagcga
     2281 tttttactgc ttctgatttt gtattagtat gtgcagtcgc tttagaattt ccagcacctt
     2341 tgacattcca accaccattg gaattaggta caacatgttg attttttccc atagttttca
     2401 cctccatttc tatagaaata ttttatcaaa tagaaatgga gaaattcaat aaacgaaagg
     2461 agaagtgata tggcatatac cttgcaacaa gaacatcaaa ttctcggttt gattaaacaa
     2521 cgcaggaaac aattacaaga tgaccgtgca gcgcttagaa aagccgatga gctatcagat
     2581 aggcaagctg aactaattgc ttctgaactt gaggatttga gaatgctaga aataaaaaat
     2641 agggagatta gattatgaag aagacagaca cactttttat aggattcatt ttggggttat
     2701 tagtgattgt agcgcaccaa agtattatcg ggggaagctt gttcgcagca ttgatggttt
     2761 taatcaatct gcttgattca aaagaaagga gcaactatgg cacgagaaga agcgctaaaa
     2821 atcggtaaag tgattgctga taatcggtgg ggaaatagcc gccctattat tttaagcaag
     2881 caacatatcg aaaagcaaaa agcatggcaa caaataaaaa agtgactctg ccagccagca
     2941 aagagtcaca tacaaattta taaaactagg agaattatat cacatgaata agaaaattga
     3001 aaatcttatc gaagaattga aacgtgaatg ccaaaagcaa ggtgtttcta ttatttgtac
     3061 agcccaaaaa gaaggggaac ttaaaagtct cgtttatggt gagacaacag aaattttact
     3121 ttgtcttgct atgcaagaag aacatttaga tgaaaatctc ccattgtcag cacatattat
     3181 gcgtagaatt gctgtggatg cttacgaaca agcgaaaaat gaagaagaaa atcaaccttc
     3241 aaatcatact tttgttatta ataacaagga agatttagct gatgtgatga ctcgtattct
     3301 caagggggaa tttcaatgat gaatgaaaaa acaattgatc tactcattat tttatttttc
     3361 acgttagtga ttgtagcgaa aagttatgta atctttggct tgttattcgc aattaccatg
     3421 cttgtgcttt gcgtgttagc aagcagaaaa gaggttaaac atgaacgagt tagcaaatct
     3481 tgacaactat ttaactgatc ctgattatgc taaaccacca tatgaagcac caattgatga
     3541 ggaggatgaa gatgagtaaa tctaccttag aaatgagcca tcaagaatgg cttgaagacc
     3601 gtaagaaagg catcggaggt tcggatgttg gaacaatttt aggattgaat aaatggaaat
     3661 ctccttatca actatggcta gaaaaaacag gacaagtagt acttgaagaa tcaggaagtg
     3721 agcccgctta ttggggtaat gttttagaag aagtggttgc taaagagttt caggaacgta
     3781 caggcaaaaa agtacgcaga agaaaccaag tatttgaaca tccattacat ccatttttaa
     3841 gagcaaatat tgatcgggaa gtagtgggag aaaatgccat tctggaatgc aaaacagcca
     3901 atcaatttct cggtaaagaa tgggaaggcg aagaggtacc gcttagctat ctctgtcaag
     3961 ttcaacatta catgaacgtt ctaaacaaag actattgtta catcgctgtc ttaatcggtg
     4021 gtcaaaaatt tatctggaag cggattgaac gagatcaaga gctgatcgat acaatcactg
     4081 aacaattagt agagttttgg gaaacaaacg ttcttggagg tatcgagcca attattgatg
     4141 gtagtcaagc gacagctgat ttcttgaaag agaagtatgc agatgttgaa gacgttcaaa
     4201 cgacgttacc aattcatttc gatgaactag ttgaacagaa aaacgaactc aaacggacta
     4261 agaaagaaat tgaatcagct atccgtcaag tagacaacga gattatcagc gagctaggta
     4321 aacgtgaagc cagtatcggt atcactcaaa aaaacatcat cagttggaaa tttgtccgta
     4381 cgagacgtat gaactcgaag aaactagcag agaaatatcc agatgtcgca aatgatgaag
     4441 agatttataa cgttactgaa tcaagaaggc taaccgaaag ggagatcaaa taatatggca
     4501 acaaatgaat cgttaaaaaa tcaattggca gcaaagccac agaaacaagt tgcaccaggt
     4561 caattaggac ttaaagcttt gatgaataca ccaacaatga gaaagaagtt cgaagaggtg
     4621 cttcatgaca atgctaatgc ttttatgtcg aatgttatga ctcttgtatc taatgacagt
     4681 tatcttgcag atagtgaacc gatgtctatc atgagtggtg cgttaactgc tgcaacatta
     4741 aatcttgggc tagataagaa tttaggttat gcatatttag ttccattcaa tagtaaaaac
     4801 aagcaaacag gaaaatggga aaagaaagct caattcatgc ttggctataa aggatatatc
     4861 caattagccc aacgatcagg taaatacaaa gcattaaatg tgatcgaagt ttacgaagga
     4921 gaactaaaaa gctggaaccg actgacagaa gagtttgagt ttgatccaaa tggtagaacg
     4981 tctgatgaag tcattggata tgttggctat ttcgagttac tgaatggatt caaaaaaact
     5041 gtctattgga ccaaacaaga aatcgaagct catcggattg ctaacaataa agatcgcgat
     5101 aagacaaagt taagtggtgt gtgggcatct gattacaatg caatggcacg aaaaactgtt
     5161 ttgagaaatc ttctttctaa atggggaatc ttgtccatcg aaatgcaaga agccaccaca
     5221 tcggatgaga gagtccaaag ggttcaagaa gacggcagca ttattgctga aacagaagtt
     5281 gaagaagata ttcctgaaag aaaagaagca gaggttatat ctgaagaaaa tgaagatgta
     5341 caaactggat tatttgatgc atctaatccg ccgttaaaca aataatgagg gagctttctc
     5401 ccttgctttt ctagaggaga aatacgaatg aacacaggat atgtcaaatt acatcgaaaa
     5461 gtgatgaatt cattcgtttg gaccaatcct tatatgtata aattatggaa cttgtgtttg
     5521 atgaaagcga gtcatgagaa tcgcaagata ctttttaatg gaaaagagat acaagtgaac
     5581 agcggagaat tcgtcacagg gcgcgatgct atcacatctg agatgaacga aggcgtgaaa
     5641 cgtgaacatc aagtgaacag cggttctgta tggagatggc taaaacaatt tgaaaaaaac
     5701 ggaatgttga acatcaaatc aactacgaaa tacagcgtta tatcaataaa aaactggtct
     5761 ttgtaccaaa gcagtgaaca acaaatgaac atcaaacgca caacaagtga acaacaagtg
     5821 cacacaaaca agaatgaaaa gaattataag aatgaaaaga ataataaaac atcatcgtcg
     5881 caaccacgca aaaagcgtgt ttacgacacc gactcagttt actacattct cgcggaggag
     5941 ttattcaaac agatttgtca gaatcaggaa atcaaaaagc cgaatctgca aagttgggca
     6001 gatgacattc ggaaaatgat cgagatcgac aagcggaccg aaaaccaggt acggggaatg
     6061 attgaatgga gtcagcacaa tgtgttttgg gcatcgaata ttttatctgc taaaaaattg
     6121 cgagaaaaat acgacacaat ggcagcgcaa gcaaatcgtg attataaaac aaaacaaact
     6181 aaaacgcttg aatacgagaa atttagcaca gatgagttgc ctatttgaga ggaggcgtag
     6241 gcatggaaac tgttggggaa atcatggaaa agctgataca gaaagtgctt gtccaacgtg
     6301 gcgaatgtcc tgaatgcgga cagcctttgt atggatggcg tacgaagaac cctgatggct
     6361 cagaacgttg taagccaacc tgtatgcaat gtgggtataa agcattgcga gttcaggaag
     6421 acttacaaac agaacgaatt tacaacgaga gcctgaaagc aagagcaatc aattttttca
     6481 aaggtggttc tgttgtgcct aatcaagcgt tgtttgattg cacattgcag aattatcaaa
     6541 ttgtcgatca agaaacaaga caagcggttg aagtaaccaa acgctttgtt aattcagtct
     6601 tgttaggaaa tccaagtcac cttgttttaa ctggaaaaca aggaacaggt aaaagtcacc
     6661 tagcgatggc agcggcttgg gaagtcttga agcgatcaaa ctacgataaa aaaatcttat
     6721 ttatcgggtt acaggaaatg ctggatcaaa tcaaattttc gtacaacaat cctgaactca
     6781 gaaaaacgat tgagggatcg ttgattgcag atatcaaaac agcggattta gtcatcattg
     6841 atgatatcgg ttcagaacta ggaaaagatg catcagatag tcgagcgttt ggcataaaca
     6901 cgctaaattc gttcttggat gcacgacaga acctagcaac gattatcaca acgaacttgc
     6961 ttggtgaaga actgaaaaaa gcttacggta cgagaacaat atcaagaatg tttgtcaact
     7021 ctgatggatt tacgatggta ttttctcaaa cagcagacaa gcgcataaaa ccagtcaaag
     7081 gagcgatcgc atgaatttga ctaaacaaga aaaaagaatc tgtcgtcaga taatgttgca
     7141 aattataggt gatcgtgaca tggacgaatt atctcaacaa gagagtcgaa tggttcggaa
     7201 gataagtaag ctaattattt atcgggatac agaaagattt ctcactgttt taggtaacgt
     7261 ctacgagaat ccagagttat tggaggtaga gtaattgcca aaaatattag atgcatgttg
     7321 cggtagtaga ttgttctggt ttgataagaa caattctgac gtaacattta tggattgtcg
     7381 tcagcagtat gaagaattat caacaggtca tgtgatcaat gttgatccag atgtggtcgc
     7441 agactttcgc gatatgcctt ttgaagatga tgtgttcgat atggttgtat ttgacccgcc
     7501 acacttaaga catgtcggcg aaaactcatg gcttgccaaa aaatatggaa aattagacga
     7561 actttggcca gaagacatca ggcaaggttt tgcagagtgt atgcgagttt tacgaccttc
     7621 aggaacatta atttttaagt ggaacgagga acagatacca ctttctgatg tgttagaggc
     7681 tattggagaa cagccattgt ttggtaataa acgaagcaaa acacattggc ttgtgtttat
     7741 gaaaaaattc agctaacgga ggaaacaaag gaggaaaagt aatgaagatt gtattaaata
     7801 aatgttttgg tggctttggg ttgagccatg aagcaaaaat ggaaattttt aaaagaaaaa
     7861 atattgaagt attcccatac atcaataact ttagctatga ctcagatgat gaatacacga
     7921 gatacacagg ccaaaagcta ggttcgatgg attttatcta ctatttcaaa aaagacccga
     7981 aaatcgacaa agttacagga atttatagcg aaattgaccg actgtacgga attgctgatg
     8041 attccagttt ttcaagtgat tcaaacagag gtgataagga cctcgttgct gttgtcgaaa
     8101 aactaggaag tgaggccagt ggaccatatg caagtcttaa agtcgttgat atacccgatg
     8161 gggctgagtg ggaaataagt gattatgacg gcgttgaaac tgcacattat ggttttcaaa
     8221 caggtagtat ttagtccact aatgacaact aaagaggagg cagaaggatg agtgaagatg
     8281 aatactttga acagtagtct attaacgaca gagattttta actggaaagg ggtgtagtca
     8341 tggacgcatc ggaagtagta aataaaatta atagtctcaa agaggttttc ggagacgtcg
     8401 aagtagtgat aaacgcacaa ggctatgaca acgaattttt taagcagatt accgacatta
     8461 gcattcagca aggaatggaa gacgaagacg gaaactttat cgatgaagta gccattttag
     8521 tgacttgcga gtaagtaatt gacagctaaa gaggaggaag cggaatgaaa ctaaaagacg
     8581 gattttactc cagcggccac ggcatcggcg gtttaatgct agatatgccg acaaagaatc
     8641 ctaaaacacg taagaaacca aaattcaaag tcggtgacat ggttcgctgc gaagcagaag
     8701 gattcatcta tccatttcgt ggatatgtag aacacgtcta taatcactca gcaatcattc
     8761 gcattgaaaa cacgatggaa tgtgataagt ggttagcgaa aagcaaagag aatttagcag
     8821 tggtgagatt ggtggacatg gaagttataa aatcttaatt ttgctttttt acaactatcc
     8881 tacaacaatg agcgttattc cacaactgga aggagaagag gcaattgtga acattttaga
     8941 gaatatagat attaagcaaa caaggaaaaa tgctagacga ttactaaaaa gatacagaaa
     9001 tttagaacgt ttggtcggac cagtgaaaat agacttttcc gtgatgactg ttaccaaaaa
     9061 tttgaaattc acaattgaca gtcaaaacga agaaatcatt gaagcgataa gtactcgaga
     9121 ttcggttatc gaagcattaa cacggctaag tagaatccat ttccaggtac tttattatag
     9181 ttattgtttt cctaataaga tgtcaatgta tcaaatagga gaaaaattag gatattccga
     9241 tagaactatc gagagaatga aggcagtagc tttggttgaa tttgctgagg cgtataaatc
     9301 aggagaactc atttcacgta caaaataaaa aaagtcggat tcctccgact atgaataata
     9361 tttccgacat aagtattata tcataattgg gggaatcaga ggatggtact tttcgatgta
     9421 aagaaatatg agacaccaag cgcgaaagat gttgatatgg aacgcacaaa acataatgtc
     9481 gctgtgtttc tttcagcata tctatcagct agatgtagag tagggcaaca tcgagaacca
     9541 aaagtgacag catcttattc cttggttcca ccttctacag ctgatcatat atttgaagca
     9601 gaaagaatgc tgatcgataa agaagaagca caggaagaat ttgagtatct gcataaattg
     9661 tttgttcgag gctattcagc gatacagcat ccgcataagc ctgatgtgac tgaaaggcgc
     9721 aagaagatat tctatgatcg ttatatcaat ggtctgccca tttatgtaac tgctcaaagg
     9781 aataatacta gcgaagaatc ggttaaagta gaatcaaaca gaattatcat ccaatttgct
     9841 tcatcgttag aactggttgc tttcaagtag ccagttttta cactttttat acccttttat
     9901 taccaatttg gtttccattt tatacctttt ttataccaat cacttaccta ttcaacgttg
     9961 tattatgata gtgtcgaaaa attaggaaac aggatcgaca aaataaaatg taagggagga
    10021 aatctccctc atcgtttaat taagcttcga taggcagcaa cggaaatatt aagaataagg
    10081 atgtgaattt caactccttc taaattgttc ttattatcta tcatccgttg ctgtctattg
    10141 tttttttaat tattcacacg ataactaaag gtaagtgaag agaaatgatt ccattaataa
    10201 tttcaatttt tgcgctttgt cttaatgtat atatgattgg atttaaaaat gggcaaaata
    10261 aaaaatagta gcagccaaga ataattttat agtgtcactg tggcggaaag ggtagacgct
    10321 aagcatgtgt gctaggtcaa tgcttcggca accatgcaag gttcgattcc ttgccagtga
    10381 ctttggcaac cgaggcatcg gcggtttaaa aatatagggg tgcgcaattt cgtacgcgtt
    10441 ttgtgcatcg tgtaggttgc tattacataa ctggttaggt tagattgaga tttgggattc
    10501 ggtacaaatg aatcgtcaaa tgtctcaagc acaggatcgg aaacgtccct gcctgtgcat
    10561 tacatattag atcactcttt gagtggtctt tttctttaca taaaggaggc tacataatga
    10621 gaaactactg gtatgtatcg ctaactaatg aatatcctcg aaccattgat gattgttcag
    10681 tgcgtgttgt gcgttctgta caaatcaaag ggaagtactc tattgtcgaa atggggagag
    10741 aagcagaacc atgtgagatt gatgcgtgca agctcgttta ttgcggtcat ggtttctatg
    10801 atgaaccaaa cattcaaaat aatattaaca agaatttgag ggattagaat gcaagaaatg
    10861 gcttaaaaat ctccaatcag gacaaatcaa gttagacaaa gtttccgatt taaagatatt
    10921 gattgaagct gatttaatgc taaaagatat tgaaaattag aaaacaaaac tcaacctaaa
    10981 cagaatgtga ggtggtgtgt attgaatggc aagacaacgt gatccaagac gtgatgaagc
    11041 caaaagaatt tggttagaat ccaacggaga aaagcagtta aaggaaattg catctgaatt
    11101 aaatgtttca gattctcagg ttagaaaatg gaaatcgcaa gacaaatgga gcgctgaatt
    11161 gattagtaac gttaccaatg gcaaaagtaa cgttactaat caaggtggcg ctcctattgg
    11221 taatcaaaat gctaaaggta acaaaggaaa tagccgagct tctccgccag tgggtaataa
    11281 aaacgctttg aaaacaggtg agtatgaaac aatatttttt gacacgttaa ccgataatga
    11341 gaaggacatc tattctagtt tgaatgatga tccttctttt gctttgtccg aagaaatacg
    11401 acttcttaaa ataagacaac ttcgaatgat gaaaagaatc caacaagctg aagctggact
    11461 aaatgatgaa gaagtcgaac gattgcagca gctaagaaag attaaaactc cgattgaaaa
    11521 aaatggtaaa aagctagaaa tcaagcgtga ggttatgcaa gatgtgcaga ttagcagaaa
    11581 aaaacatcgc aaaattgatg atattctttc aattgaagat tcattgactc ggattagcaa
    11641 ccagttagct aaagccatca agcaaatgaa tgaactttat atgaatgaat acagaactga
    11701 tttaattaaa gctcagactg ataagatcca agctgagaca aatgaaattg gcggaaataa
    11761 ttcaggtgaa gaaatagaag aatggaaaca ggcagtttta aatgccgcaa acaaacgggc
    11821 ggtgaaagaa aatgaataat gaatttattc cttttgctga tattggttct gccattgatt
    11881 attactatga taaaccagta gctttttgcc aagatatttt gcatttgaat cctgatgaat
    11941 ggcaagaaaa tgttttaaat gatttagctg aattttcaaa ggtttctgtt cgttctggtc
    12001 aaggagttgg aaaaacagca ttagaagcag gagcaatact ttggttctta acgtgtcgac
    12061 cctacgctaa agtaatagca acagctccga caatgaagca actttacgat gtactttggg
    12121 cagaggtagc taaatggtta aatgatagct tgatcaaaaa cttactgaag tggacaaaga
    12181 ccaaaattta tatggttggt gattcagagc gttggtttgc tacggctaga acagcgacta
    12241 aaccagaaag tatgcaaggt tttcacgagg accatatgtt gattgtggta gatgaagctt
    12301 ctggtgtgtc tgatccaatt atggaagcta ttcttggtac gctatcaggt tttgataata
    12361 agctgttgat gtgtggaaac cccaataata ttgaaggtgt cttttatgat tcccataatt
    12421 cagaccgtga taaatacaga gttcataaag tatcaagcta tgatagtaaa cgtacaaaca
    12481 aagacaatat agaaatgatt cttaaaaaat atggaaaaga aagtgatgtt gctcgtgtcc
    12541 gtatttttgg agaatttccg aaaggtgcgt tggattcatt tatcagtctt gaaacagttg
    12601 aattggctac agaaaaacaa attagtgatt ctttagtcaa taaaacaaag gttgctcata
    12661 ttggtgtcga cgtagctcga tatggtgatg attctacgat tctctttcct agaattgcta
    12721 ccagggcatt ggagtatgag aagtattcaa aacgtagcac catggaaaca acaggatatg
    12781 tcatcaacat ggccaagaat ctaatgagtc aatatccgag tattgataaa gtgatgatta
    12841 aagtcgatga cactggtgtc ggaggtggtg taaccgaccg cctagaagaa cttatagaag
    12901 acaaacatta tccttttgag gtgtttggag tgaataacgg ttcaacatca gaagacgatt
    12961 tttacgataa tttaggtact caactatggg gaaacatcaa ggaaatgtta gaagaaaata
    13021 tgacagcaaa tcttaacgga gaacagcctg ttattgaatt gccttctgat agttcgttaa
    13081 tcaaagaatt aagtactcgc aaattcaaaa tgacaagtag aagtcgtata cgtttagaaa
    13141 gtaaagatga tatgaaaaag cgaaatattg gtagtcccga tattgctgac gcactggctt
    13201 tagcgtttta tgagccacca agtcactatc aatttattca attttaggag gtgagctttt
    13261 gattagtaca gtattatctt tagagagata taagaagcta cgtgttaaat atgcaacaca
    13321 aattgaagat ggaatgtttg atccgaatgg ttttatagaa gatatgaaac cattttttgc
    13381 tgatcgcgaa agaaaatatc tagcttatac tagcgaaaag aatgaaatag ataatagacc
    13441 aaagcctaac actgatattg taaaagttaa taataaactt catgctggta tgtattcaat
    13501 tgtcgtagac caagcagtca atcattttac tggtatacct atcaaatggg attacgatgt
    13561 atcggaacaa aaaagaacac tcattcaaag attaaaagat aaattcttaa aaaatgatat
    13621 agaacttccg acagttccag aagcttttaa caaattaaca agcaatcttg attccatgag
    13681 attcgcaatg cttgattctg aaactgcaac ttttcaagga gcttgtggag tagctttccg
    13741 attgctagag cctgtggaag aagatgatgg ttggaagtta agagcaagta atattgaacc
    13801 ttggagagca gaaagatatg gaaatgccgg aatctatatc aaagaaaagt atgactctta
    13861 ccagaaaaaa ttttttcaag aaatgaaagt tatgacaaga aataaaattc tgacatatgc
    13921 ttgctatggt gatttgaatt ttgttacaag cggaacgttc aaaaaaattg atgagaccga
    13981 taaccctttg gggacgatta ccttggcaga atttaaaaat aatacgaatc gttattgtga
    14041 ttttgaagta gctgaggaaa ttggagatgc aattgatcgt gctttgtctg atcaacaaaa
    14101 cgaaatcgaa caatttaagc ttgcgtacat gcttgttact ggcacaacaa tgagcaaagg
    14161 cactgctaaa gaaatgatga atcagctagg gattatcaac ttaaaagccc ctactgcaaa
    14221 agctgaatat gtcacaaaaa atttagcaaa agatttcaat gaatatcata tggatctatt
    14281 gaaaaaacag ttttacacca tttgtaaagc aatcgatttt aacgatgagg tgtttaaatc
    14341 aaacagttct ggagaagctc gcaagtggca aatcattagc ctagaagcga aaacaaatac
    14401 taaagagcaa tattttagag aaggattgaa agaatgcgca gaaacaattg ctgcttttct
    14461 taagtttcat gacaaagtag aaattgagcc tgaaaaaatt atttttactt tctctagatc
    14521 tttgccaact gatttaagtt atttagctga agctttacct aaacttgcac catacgtatc
    14581 caaacgaact attcagagcc aaattccatt tgtaacagat gttgattatg aaaatgaaat
    14641 gatggaattg gaaagtggaa gtgcttatcc agatagtgaa tacaattttg gcggaggtgg
    14701 caatagtgac gatagaaacg aagtattgga ccaaacgtcg agaactggag gatcaagcaa
    14761 ggctcaaaca agaaaatcag acacttaaaa aattaactag tgtatttcct gaagcactga
    14821 aagagataca agcaaaacta ttatcacaag ctgacttaca caatatcact tatccagaaa
    14881 tgatggagtt ttacagtaca agtaatcaga aaaaatatcg tgaatatgtg gaaaaaaatt
    14941 ataagtcatt aaaaatgtat gatgcaaaat acaaagagtt tatcgatgaa ttttttccac
    15001 catttgacta tgcaaaagtc aatcgcttat tacaaatacg atcagatgta tttaaaattc
    15061 ttgcagaata tgcgatggat gcagatgtga atcaatattt ttctgatcgc ttagaggaaa
    15121 ttcttcaaag aacatattct tctaatgcta atgtttttgt tcaactttta aacgttgata
    15181 taccaaatta tttaccagaa aatgaaatta aacattattt gaactatcca tggtcaggaa
    15241 agacattttc aagaagactt tggggaaata tttcatcgct tgaacagaaa ctctctaatg
    15301 ctattgtaaa aagtgttgct agtggagaag gcgttataca cgcattaaac accatgagat
    15361 tagactcaga aatttgtgac atgtttaagt tagaagaatc aaagtataac aaagcgatag
    15421 aaaatctcgt tcgaacggag tatgcaaaat ttgcacaaga tggtattgaa aaatcatatt
    15481 tagaaacagg tattgaggaa tacaacgtat tgactgcaaa agatgagaga gtttgccgga
    15541 tttgtggagg aaaggcaagt aagaatccct ataaactgaa agatgctgtc ataggtgaaa
    15601 atcgagcacc tttccatagt cgttgtagat gtacggatgt tcctaattta ccaaaattag
    15661 gaaaggatat tgatgaagaa tatgaccgtt tatttggcga tttattagat gagtttgcac
    15721 atgattcttt tggaattaat ttgaaacgga ggaagtagaa tgaaagattt ttttgaagca
    15781 gtactaacaa ttaatgtaaa tgctgatatt gcagaagcct acaaaacagc tattgagtct
    15841 gagaaccatc ctaatggctt gagagaccat tggaatggca attatgccta cgtggttatt
    15901 ggcgatcaaa ctgttaatta tcaagataat actccagttg ataagaatac cgttaattta
    15961 acgattcaat tattatctca ttcattacca aatttaaaag aaacagttga ttggtatgaa
    16021 aagatgggat gtattgttgt tagaactgac tacaaagaag gaaagtctag taattaggct
    16081 tttttatttt gtccgaaatg acgttaaact agcgcaatac tgggcttggt tgaatggtgg
    16141 ggcgcaacta ttaaaactca aagcaatgcg gggcgtgaaa acgaatcgtg gggcgaaagg
    16201 agaatgagca tgaaacacaa atcattaatg ccaatgaatt tgcaatactt tgccgaaggt
    16261 gacgatcaaa agttttcttt tgatgacttc aaatcttttg tggaatccaa tgaagaagct
    16321 caaaaattta ttcagtcaca atctcaaagt gttgccgaca aacaattgga agcttggaaa
    16381 caaaataact tagataaaat taaacaggat accatcaagg aatatgagga atctaagaaa
    16441 aacaagtcac ctgagcaaat tcaactggaa aaactacaag ctgaatttga agcagaaaaa
    16501 gcgttgcgtg tgacaagtga taataaagca tttgttgcag aacaaattgc tggattagaa
    16561 ctagatggag agttaaaaga gtctatttct caatttatgc taaataatct tgttagttcg
    16621 gatacagatt tcactaagaa tgctgttgaa ggttttacaa gtgttttgaa tgcaattaat
    16681 gagaaacatg cagatgcatt aaaagaacta caaatgaagt ctgcatttgg tggaactcaa
    16741 caatcgaata accaggttca gcagaacaat gaaacattaa caaatccaga agaacaatta
    16801 ggacaaattc ttcaacaatt taactaggag agtgaaaaat tatgaaaaaa acatctttaa
    16861 ataatttaga gtatttggat atttcaccag cgattaatgc tatgcaagta ccaaatacac
    16921 cttttttaag ctatttactt ggtgctggaa aaacagagcc agcaaactcg acagaaatta
    16981 aatggcgtga atatgatatc aacaacgatg attcttctga aaaacttgag ggcggagaat
    17041 atccagatgc tgaatcaggt cgaacttggt ttaacaacta tactgaaatt tttagaaaat
    17101 caacctctgt atctggtaca ttagatgcta ttaatgtgaa tggagtcgga aatgaattaa
    17161 ctaatcaagt agcactacgt ggtatggaaa tgaaaattga tttgaaccga aaattgatta
    17221 ctggtgtaaa agctgatgaa aatggttcta aaggtcgtcg aatgaatggg attttgaact
    17281 tgatcaattc agcaaataag gcagaaacag ccactgcggg tgcagtaaca agaaaagata
    17341 tcgatacttt atttaaattg atgtatgaaa aaggttatat gggagaaaaa ctatgcttga
    17401 tttctccaga tatgcaggag ttaatgactg atgagttaga tggaaaatca acaaaaattg
    17461 ttcagttcgg ggaaagagta acttttggat tgcaaattgg aaatatcgtg tctaattacg
    17521 gtacaggtat tgctctacta gaaccatcat tgccaaaagg aacaattgcc gcaatcgata
    17581 ctaattatgt gaaactacgt ccattacgtg aatggagagc agaagaactt gcaaaaacaa
    17641 cggattctag acgtatcggt cttgtaggtg aatactctct tgaatacaat gcttcaaact
    17701 ctggggcaat tttaaattta aagtctgaat aaaagggagt tagtactccc ttttttgata
    17761 ggaggaatta cagtggtaaa aaaagatgaa actaaaaaag atgaagtcgt gaaatataga
    17821 gtaggtaaaa ctaaaaattt tgttgggttt gttcatccta aaactcgtag atttatcaca
    17881 gcagattcaa ataacgaatt tatcatttct atagatgata aagaagcaat tgcaattttg
    17941 gaagatgcaa ttgatgttaa tgaaatttag gaagtgatct gatggatgaa tcgctaaaaa
    18001 cggaaatcat tgagtctaca aaagaagatt ttccagattt gagtgaagaa cgcataacta
    18061 atttattaga aataattttg ctagaaattg aatcatacaa cacttgtaaa aatgatattt
    18121 catgggaaaa gttaaaaagc gtgattagtg aagtgttgta taaaataata aaaaatgaat
    18181 cagaaaaaac agtatcttca gttagacgtg gcgatacaac gattagttat gcttcaacaa
    18241 caaatgatgt tagtgagtta cttctaggct atggtgattt gatacgaaga gttattggtt
    18301 gtggaggatt ggagtttttt taatgaatga agcagatatt ttagaaacta cttatgaaga
    18361 tagttgtatt attgaaagac tgacggacat tgaagattct aatacaaata ttactattca
    18421 agattacaaa aaagtatatg ataatcctat ttcttgcgct ctttcacaag gtcaaatcga
    18481 tggactagca gtcatagaag atggagagat ggtaaatgtt tcaactgaca catataaatt
    18541 atttgttcat cctaagatta aactaaaaaa aggagatcga ataacaataa ctcaaaaggc
    18601 cagtggctta attttttctc tatttgctac taagcctttt tactatccta gtcattgtga
    18661 agtgaatttg ataggaagtg agaaaaatgg gtaatctcaa atatgaatca aatgcagaaa
    18721 agatcattga gaattttaaa aatatgactg taattgctca aaaagaagga atatccttcg
    18781 ttaacgattc aatgaataaa gtcgttagtt tagctaaacc attaactcct gtaaaatcag
    18841 gtaatttaag gcgaggatat cgtgtagtaa aagctagaaa actatcaagc ggtcgaattg
    18901 ttggagaagt tataaacaat gaacattatt ttaaatatgt agaagaaggt cataggacta
    18961 aaaatggtgg ctttgtcaaa gggaaattca tgttaactcg tgcaacgaat cttgcaaata
    19021 tgtcttatat tcctcgaaga tttaaacaaa tggcaataaa aatcgttaag aaaggaaagt
    19081 aacatgaaag atgaaatcat tgctgcaatc agtagcaaat taaaagaaat ctatcctgat
    19141 gggacaatat atcttgattc agttatgcag tcaactaaag atttttattt cgttttatca
    19201 gtaatggaat ctggaactga aaatgtagga attgatattc aaaatgtttc tttcttaatt
    19261 gatattgcat tgattgataa taaccctaat agaaatttaa ttaatgaatt agtctcacgt
    19321 tgtgggactt tttttaatac gattacaatc gatgagcaaa tattatttcc aaaagcctat
    19381 ttacctgatg aagcagatgg tgttcaacat attcgtttta cattagaatt tccacaatat
    19441 attgaatgga gtgaaagata aatgggagaa aaaagaagta aaaccggaat tatttctgtc
    19501 gaaaaaccta cttggtttcc tttggaagat gagacaggga attttccggt atatggtact
    19561 gcgttgccaa tgggaacagc agtaagtatc aaaccaacag ctaattatga aacaacacaa
    19621 gattatgggg attcagtggt tcaagatcaa tttacagctt ttggtggtgc agaagttgaa
    19681 ctggaagcaa atggatatac tcataaagtt ttatctacaa ttactggagg gaaaattgtt
    19741 aaaggtggtg ccttgcgttc tggagaagat attgcgcaag atggtgcgtt tgcatataga
    19801 cgtaaaaaat cgaatgggaa ataccgttat acggtctttt ataaaggaca gtttgctcta
    19861 gattcagatg aaacatcaac gattgaagga agtaaagtaa gttttactca tccaacttgg
    19921 aagggttcat ttgtagatgt accaggactt ggatatatgt attcagttga tgaagatgat
    19981 gaaggcgtgg ataaagcaat gatcggaaat tggtttacaa aagtagcaat tccaattgaa
    20041 gaagcagaac tttcaggagg tacagaataa tgtcaaaata tcaaacaacg attaaattaa
    20101 cgaaaaaaga cgaagaaggt aaatatgagc aagtacaatt taaatctgct gaatttttac
    20161 caggaacagt tgtagaagat gctgcaggag ttatggaaga aatgcaaaca gcgactgata
    20221 agcaatcagt taaaaaagct ttaagtcgtg cttattcatt tattgcagat actttatttg
    20281 agggacaatt tactggtgaa gattattgca aaggaattga tgctcgtgag attgcctcat
    20341 tgacaggaaa attattgaag tctgttactg caggttttga tgaaacttat acagagacga
    20401 aaaaaagtaa gtgaggcgct caagtcacct tcatttaagt attcgattac ttaccgagaa
    20461 ttagatataa agacgcaatt actcgaagca ggttggacgt taccagaaat tgaacgtact
    20521 gacttggatg agttaatgcg tctttttgct tttagagatg cggtaaaaga gcatgaagat
    20581 gttgagtact atgataattt cactcaattt taggaggtga tactttgaat aacgatgacc
    20641 taattctgaa gatgatacta gatgaatctg gttttactgc cggtatgaat aatgctgtca
    20701 aaaagttgaa ctcttttgat gaaacaatcg aaagaaaaag tagaaatagt ggcagttcat
    20761 taggtagtat ttggaaaata tttgctggaa gttttctagc tagcggagta actagaatcg
    20821 taggagctgg ctttgatcta atcaagggtt ccataagtgg agcggttgat cgagtagata
    20881 cgatgaataa cgctctacga aatttccaaa atatgggatt tagtaattca gaaattatga
    20941 agaatatcgg aaagaatggg cttttatctc aaggtattca aggacttcct actgctttga
    21001 atgatgcgat aagtcatgtt caacttcttg cttcttctac aggtgattta actcgttcaa
    21061 ctcaaatatt taaagcttta aatgatggaa ttcttggttt cggtggttca actgatcaag
    21121 ttaatgaagc tgttattcaa ttatctcaaa gtttctcaaa cggaaaagta gacgcacaaa
    21181 cttggaactc aatgatcaac gctcaacttg gacctactct ttctgctatt gctaaaaaga
    21241 tgggaattac aatgggagat ctgaaagaag gtttatctca aggtaagatt tctgttgaag
    21301 aattccaaaa tcaattaata gaaatggata ccaaaggtgg cggaggactt aaatcattaa
    21361 gtcaaatcgc taaagattct actaagggaa ttaaaacctc tatacaaaat gcaaaaacag
    21421 ctgttacacg tggtgttggt gaggtaatag aaggattaaa taaagcatta gtagattcag
    21481 atttaggtgg atttaaggga attattgata aagtgggcag ttcaatggaa tcgttcttaa
    21541 aagtaattgc tgcaaatatt cctacagcag tatcattttt aagtaattta tttaacgaaa
    21601 ttcaaaaatt tggttctgct ttgaaattca tgatgccctt tcttgttcct gcagctaccg
    21661 cttttggagc gttcatgttt caacttaaag gtataccagc aataataaaa agcttcaata
    21721 attttaagaa tgccataatt ggcgttggaa attcattaaa gattatgggg gcaatagctg
    21781 ctgctaatcc atttgtttta attattggtg cagtcgttgg tgcaatagct gttttcggtt
    21841 actttatggc aaccaatgaa gagcttagaa acaaggttat atctatttgg aatgatgtga
    21901 aagattccgt aattggtgta ttaaaaaata taaaggactg gggaattgat acttggaatt
    21961 ctgctaaaga aatggcatca aatgcagttg agggtgtcaa agatgcttgg tcaggaacaa
    22021 aggaatggtt ttctaacacc tggaaaggta ttaaggatgg ggccacaggt ttatttgata
    22081 aaacagtaga gacttcaaga aatgcagtcg atagtgtaaa aaatgcatgg tctaatatga
    22141 agaaatggtt ttctgatact tggcaaagta taaaagattc agccagagaa aaatggaatg
    22201 gaatcaaagg ttctattatg tcagttgctg gtccattgat tacaggtata aagaatgcat
    22261 ttttacatgt tactttttat ctagagacct tatggaataa tttagttgag attggtaaaa
    22321 acgtctttga gattttaaaa aatgttatac ttgcgccggt tttgtttatt acctccatga
    22381 tttctggtgg atgggaagaa acaaaaaata atatgattgc tgtttggaat aatattaaag
    22441 aaagtgccat aaatatttgg gaatctataa agaatatatt tgtaagttat tttacaaata
    22501 tttattttgc tgcactcaat atttggacag ggttcaagct tacattgata aatatttgga
    22561 atgaagtggt aaatcaagct aaatcgattt ggttaaacat aaagtatttt tttattaatc
    22621 tttggattga tataaaatat tttgcaattc agaaatggat tgaattgaag ttttctatta
    22681 ttcaaacttg gatcgattta aaatataatg ccattactac ttggaataat attaaacagt
    22741 ttttcaaaga tacttggaaa aatattaaag atacggcata caatacgtgg atttctataa
    22801 aaaataccat gattaataca tggaataaca ttaaggactc tttctggaat attgttactg
    22861 gaattgttaa ttctgctgaa aatgcatgga caaatctaaa aaatggtgtt tcaaatgcta
    22921 ttaatcgggt aaaagaaatc tttaattcgt taagggaagt caatttattt gaaattggca
    22981 agaacatcat tgatggactt ataaatggtg taaaagaaaa gtggaatgct ttgaaagata
    23041 ctatcaaagg tattgcaggt aatatcaaaa attggattaa aggagcttta gatattcatt
    23101 ctccatcaag atggatgcgt gatatggttg gtaaaaatat tgttcaaggt attatcgttg
    23161 gtattgataa agagcaaagt aagttagatc aaaccatgac aaatttagta aaaacaccgt
    23221 ctgttcaacc tgtagtaaat ggaataagtc acctaccccc tatgttaggc tagttgtcgt
    23281 ataggataat aagttataat aaagactata cggaggatga ttaccatgac aaataaaaac
    23341 aatgaacgtt actctaccga actgaaagcg acagccatca agaaaatgat gccacccgaa
    23401 aataggggga ttcgccaatt aagtcaaact ttgggcattc cagaagcgac tctttattct
    23461 tggcgtaaaa aagctagaat tcaagggaat actacacccg gaacgaaaaa aaatgtcgaa
    23521 aaatggtcaa gtgaagataa atttttaatt gtgatggaat cattctcaat gaaccaagta
    23581 gaacttgcgg aatattgccg aaagaagggc ttatttaaag aacaaattga ggcttggaag
    23641 aaaacgtgct tatctgcgaa tgaacaggaa gaaaatcgaa cgagagaact tgcaactgaa
    23701 ctaaaagaag agaaaaaaca agcgcgtcaa ttagagaaag aattacgtca taaggaaaaa
    23761 gcattagcgg aagccgctgc tctcttatta ctaagaaaaa aagcacacgc gatttggggg
    23821 gaccaagagg aagaatgatt tcatcttcag atcgcaaaca agctgttgaa cttattcaag
    23881 aagccaatcg caatggggcc cgtctcacct atgcctgtaa tgagctgaat attagcgttc
    23941 gaacctacga acgatggacg cgtgaaggta cgatagcgca tgatcaacgc cctttggcga
    24001 aacgtcctgt acccaaaaat aaactgacgg atcaagaacg cgaaaaaata atagaaaccg
    24061 tttcaaaaaa agaatttatg aatttgccac ctagccaaat tgtaccaaaa cttgcggatt
    24121 gctcgattta tattgcatca gagtctagct tctatcgtgt attgcgagaa aaaaatatgc
    24181 aacatcaccg tggccgaagt caagtttcac aaaaacgcat accgccaagt caccttgcga
    24241 cgaagccaaa tgaagtttgg acttgggata ttacttggct aaaaggtcca ataaaaggac
    24301 tcttttaccg gttatatctc atcattgatt tatttagccg taaaatggta ggctgggaga
    24361 tttgggaatc agaagaagct cgtcatgccg aaaaacttat taaacagacg gtgcttaagg
    24421 aacgtatcca aggacagccg ttggttttac actccgataa tggcagccct atgaaagccg
    24481 cgacttttca agtcttactc gaaaaattag gaattcaaag ttcttattca agaccacgag
    24541 tgagtaatga caatccttat tcggaagcgg ctttccgaac gttaaaatat cgaccagaat
    24601 atcccaataa cggctttaaa acaatagatg atgctcgaaa atggacgaaa gagtttgtcg
    24661 attggtataa cgattctcat ttgcatagtg ggattcaatt tgtgtctcct gcagcgtgtc
    24721 atgaaggacg acatctcgct attttagaga aacgaaagca ggtttacgag gacgctaaaa
    24781 agcgccatcc tgaacgctgg tcaaaaggtg ttcgaaattg gactccacat caatcggtgg
    24841 cgttgaatcc tttaaaagaa acagaaagtt aacaggagca taatctttca agattatcaa
    24901 ataaccctcg tcacccaata ggggaaaaag ttattcttcc cctattggat aacgaggcca
    24961 accgaccata gggaggttct gctttttgat aggtggaaaa taaaaatacg acaactatat
    25021 tgacaaacac cgcctaccaa ttacacaaac aaagcaaaat atatctgcta gtgaaacaaa
    25081 agaaattcat ttacatttaa atgtttatgg agatttacct gattcaatgg ttcggaagat
    25141 taccacaaaa attaaaacag aattgacaag acaaatgaaa cgagatgctg gtgcagtagg
    25201 aggaacatta tatgcaactt aagagaggac aattttttat taatcaacat tattcttctg
    25261 aatttaatgt gtatattcaa aacaggcctg cttctgtttc agctagtcga gtaattgaat
    25321 tgagagagcg agaaggaaat gattctatca ttattgataa aggctattac aaaaatgtga
    25381 ctagaaagat tgagtgttac tataaagcac cttcaattga tatggtgcag gagtgggaag
    25441 atcgaatcac tgaatggtta gatatgtcgt cttatagtga ttttattctt tactatgatg
    25501 aacaatatat ttatcaagct gtagtaatag aaggacctga atttaaagga acaagaaaaa
    25561 caggaaatat tgtccctttt gaatttacag tgagtattcg accatttaag gaaaattaca
    25621 atggtagatt tactattcga caaacagaaa cttttgaaat ttataaccca gagaagtatt
    25681 cttcaaaacc gcttattaaa ttgagtggtt ctggagatgc ttctttttat attaataagg
    25741 ataaatatga tttgaaatcg ttggacagag aattatttat agattctaaa ttagaagagg
    25801 cttatcgaaa attagatggt aatttagaac atcaggatca ggtcacctta tttttagatt
    25861 ttccattttt atatcctgga aaaaatgaaa ttaaatggac gaaaaatatt cattcatttg
    25921 aaataatgcc taggtggtgg agaaaagtat gaaaccaaga atatatagtc ctactgaaac
    25981 agatttctca acgaatggct taggaatttt aaaggattgt acaagatgtg gaatatatga
    26041 agtagctaat ggaaaatatg aattagagtt ggattatcct ttaggaacta gatttgatga
    26101 atattttgaa aatgactatc aaataaaagc aaagccaaac gatcaagaag agtatcatat
    26161 cttttttatt gatgataaag atatagatac ttttttaaat acagtaacta tttatgctca
    26221 gagtcgtaca aatcgacttg gaagacgggt agtcactctt gtggaagtgg actctaaaac
    26281 tggtcaagaa gcgatatcaa ttattgaaac taaaatggat aaaaaatctg acatacgact
    26341 ttattctgat attacggctg tttctagcac aatctttgaa gcgagaaatg ttttaaattg
    26401 tattgctggt gaacaaggat cattgcttca atattggggc ggagaaatta aacgtgaacc
    26461 atttaagctt tctttgttaa agcgaagagg tcgcaataat gttggaacga ttcggtatgg
    26521 aaaagatatg tctggtttga aggtcaaatt agattggaca ggtataaaaa caagaattat
    26581 tccatatgct gatcctcaaa gtgaagtagg tacgactaat cgaatttatg gttcgccagt
    26641 agatagtgcc tatattaata actatcctga tgtctataca gaacatgttc agtttacaga
    26701 agaacaagga gtaaaagaca ttaagagctt aaataaaata gctaaaaatt actttaaaac
    26761 gatcaatcct ggctgtgata agcctaaagt ttctattacg gttgaatttg ataagttgac
    26821 tgatagtgaa gaagcgaaag aatttgcgaa gattagaaat tatggtctgt ttgatacatt
    26881 taaaatatat cataaaaaat ataatattta tcttgaatca aaggttagtg gactacaata
    26941 cgattcttta tctgaaaaaa ctttgaaatt agaagcagga gacattcaag ttgcttttta
    27001 tcagcaacaa gctgtaacta ttcaggataa attaaaagat tatgcaacga ataattatat
    27061 gagtgatttt aatgattatg tttcttcaat gattacaggt caaggcagtg caggaggata
    27121 tgtagtttta tggccaaaag aaaaaccttc caacatcttt attatggata atccagattt
    27181 agaaaaggca agagaagtac taagaatgaa taaaaatggg attgcttttt ctaagaaagg
    27241 atggcggggg ccttttaatt cagcttggac attagatagt atatttaatg ccaattttat
    27301 acaaactgga ttaatcaaag cagatatctt tcaaaattct tttaacaaga ctggagatgt
    27361 attgaaatta gttaatggac tactccaaat ttggaacaac aaaaagaaaa taatggagtt
    27421 aactaaaaaa ggaatggaat tttggaattc taagggttca attggaacga ttggaacaac
    27481 tgattctgtt ggtaatcctt ttcctggggc ttctactcca acccctattg aagataattc
    27541 tttagttatt cgtacaaatg gagacggcaa atatattttg atttctccta aagtaggaaa
    27601 aggattagtt ttattaggaa atggtaaagc aatttatttt ggagacttag atgtacaagg
    27661 aaaacttaca gttaaaggaa aagaaataat tcctggacaa ggtggtggtc catcgggagg
    27721 tggagaatct actggtgggt atcctagtga attaaaaaca gatgcagaaa agagagcttg
    27781 gagaatttac gatattttgt gtaataacgg atttacgaaa caatctgcat gtggaatatt
    27841 ggggaacatt caacaagaaa caggaggaac ttttgatcct gatactgttc aaataggtgg
    27901 accagcatac ggattagttc agtgggatgg ttcttcatat cctcttgttg gtccagcaac
    27961 atgggatgga aaagtttatg ttcaaaactt atttaatgct gcaggtatta aagaaccaat
    28021 aacgagctta gatgcacaag ttcgattgct tatttggaca tttacaaatg gacaatggat
    28081 gg
//
LOCUS       DAMEEU010000032        27915 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.033, whole genome shotgun sequence.
ACCESSION   DAMEEU010000032 DAMEEU010000000
VERSION     DAMEEU010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.033"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            207..1373
                     /locus_tag="PB779_001408"
     CDS             207..1373
                     /locus_tag="PB779_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0738939.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            1790..5017
                     /gene="fss3"
                     /locus_tag="PB779_001409"
     CDS             1790..5017
                     /gene="fss3"
                     /locus_tag="PB779_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HDE0738940.1"
                     /translation="MYKKQKKKLCVLTILSLAVQSIVGAIAPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCVEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIADYQKKPSFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENTANIDYRVN
                     GNQLIISPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTVKIDVE
                     MEGSLKIKKVDKESGDIIPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTATIKAGETISVTSKNTREKGQIILDKTGIETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGHETQGKAEFKRAEYTL
                     FTVKDGKAVKWTENFKPELLKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDSEKNAVITRDVAAKEQVIRFGFDFFKFAGSTTGTAETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDYTKSDYIFTITEKGQKQPIKTVTVPYGNLTNENFSVSLNR
                     LMLYDLPEEEDSLTSLATWKEGDKELTTLDSTELVDKLSYNLHEIKEDWYIVAQAIDV
                     DATKAAQEKDKKAKPVAIAETTATLANKEKTGTWEILHKLTVEQVLDKTIVLFNYVYE
                     SKEAYEAGDEPVAKDASLNNQAQTVNCMVERHVSIQTKAHLEEGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALFPDGTSKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYDKDGNINGKHNEDLKEKSQTLTPKKVPTTPSTPEQSEMPTVP
                     SGSQESSPTVKAFPQTGEKTSNVLLFIGFSLIFATAGYYFWNRRN"
     gene            5129..5443
                     /locus_tag="PB779_001410"
     CDS             5129..5443
                     /locus_tag="PB779_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDE0738941.1"
                     /translation="MELKFVVPDMVETFGKLTYGGEGEVLSEGYGRNTTIVGRSYHLF
                     SNKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLIAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            5456..5830
                     /locus_tag="PB779_001411"
     CDS             5456..5830
                     /locus_tag="PB779_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HDE0738942.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQLNQGKPTNQNEGKK"
     gene            5831..6184
                     /locus_tag="PB779_001412"
     CDS             5831..6184
                     /locus_tag="PB779_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HDE0738943.1"
                     /translation="MKNMEINVEHILDCLDQFGKGELTEEQLTNALTYDEKMFLIMHQ
                     GLLEVGNDAKEDFDVLDWLGEEESFFMVVEVNESLCRQAESVLEEIDVEMPDAIERFL
                     KQLVETKQLPVVVND"
     gene            6253..7269
                     /locus_tag="PB779_001413"
     CDS             6253..7269
                     /locus_tag="PB779_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HDE0738944.1"
                     /translation="MYKGHRIRAGDQHLIYHFVLGWLIFLFIGWMSVFYLQELRQFDI
                     SKVSFSTSEIGWSMKDVICLLGSLALSGSMMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQGEGFFKDLNSSWTKESISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LENKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIEEIVAENGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIQALLKSDAELFILDPKNADLADLGTIMPHVYSQK
                     EEISECVEDFYERMIARSRSMKEMPNYKTGENYAYLGLPPNFLIFDEYVAYMGANRFP
                     TSIE"
     gene            7863..9737
                     /gene="ltrA"
                     /locus_tag="PB779_001414"
     CDS             7863..9737
                     /gene="ltrA"
                     /locus_tag="PB779_001414"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDE0738945.1"
                     /translation="MNVETDEVQGSGKNVGKSVMEVPRLNTKIRYWEYYDLQETFDQL
                     FTQSRNGKKFYQLYELIISENNILLAYRTIKANKGSSTPGTDSFTIDNYKEMNQAEFI
                     HLILSHLENYKPKSIKRVMIPKPNGEKRPLGIPCMIDRMIQQMFKQILEPICEAKFYE
                     HSYGFRPLRSAKHALGRIMYLINISKMHYAVDIDIKGFFDNVNHRLLIKQLWNIGICD
                     KQVLAILSKSLKSPIQGEGIPSKGTIQGGIISPLLSNVVLNDLDHWVSKQWHTFETKY
                     PYTKGYNKFRALRDTNLKQGYIVRYADDFKIMTNDYPTALKWFHAVKLYLKDRLKLDI
                     SNEKSKIVNLRKCKSEFLGFAICVKQKGKKWVCNSRISNKKKDQIKEEIKQRIKDIQK
                     SPTAQNALLFNALVLGVHNYFRYATHINLDLNRMNYVLSFTTYNRLSNCSTRCYPNKA
                     SPTYKKFYSTTMKTYKVAGVYLYPLCDVSTKTIYGFNTEDTPFTPFGRQRLEHKSLQS
                     LVFQELRKLMESKIPNRTVEYLDSRISRYSMKSGKCEITKQFLPAKAVHCHHYLPKSL
                     GGDDKFDNLRIIHKDIHLLIHTTNKMIIDHYVHELKLVPEQIAKINLYRKMCNLQNIQ
                     "
     gene            9863..10219
                     /locus_tag="PB779_001415"
     CDS             9863..10219
                     /locus_tag="PB779_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HDE0738946.1"
                     /translation="MILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQFNFRV
                     ALGRMSELGYSMMFGEVDKNFFMKRIKGRGYVDTGGSVISEFYTPLVPKGYDFLREIS
                     NIVGLTVHTERENNSV"
     gene            10264..11406
                     /gene="dcm"
                     /locus_tag="PB779_001416"
     CDS             10264..11406
                     /gene="dcm"
                     /locus_tag="PB779_001416"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HDE0738947.1"
                     /translation="MTFLDLFAGIGGFRLGMEQAGHQCIGFCEIDEFARRSYKAIHDT
                     RKEVEMHDITSVSDEFVRSLGPVDILCGGFPCQAFSIAGKRQGFSDTRGTLFFEIARF
                     ATLLQPKFLFLENVRGLLNHEGGATFETILRTLDGLGYDVEWQVLNSKAYVPQSRERI
                     FLIGHSRDACTEQVFPIIGSSSTSDQNIRNLVNINPSNRGMGGQVYGSDSVAPTLTGD
                     EGIKIALPVKDGISVAGMLSGNFEQGNRIYEVTGTAPTLSTKQGGTKIMIRKNETEYQ
                     EVKPGDSVNLAFPNSTSRRGRLGKQSVHTLLTGDQQAVVTDQYQIRKLTPRECWRLQG
                     FPDWAFDRASQVNSDSQLYKQAGNSVTVPVIFDIARRLKGVKAYDL"
     gene            11396..11685
                     /locus_tag="PB779_001417"
                     /pseudo
     CDS             11396..11685
                     /locus_tag="PB779_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            11941..13125
                     /locus_tag="PB779_001418"
     CDS             11941..13125
                     /locus_tag="PB779_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDE0738948.1"
                     /translation="MAQRNLDYRLLKERRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     IASTKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDVRKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPDLTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAYYAIQDLL
                     KGRSIESTTFSIINRYLRFADKVDGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNQTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     IV"
     gene            13122..13235
                     /locus_tag="PB779_001419"
     CDS             13122..13235
                     /locus_tag="PB779_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HDE0738949.1"
                     /translation="MKRGILMEIVKDMLLVLGGSMLGVTVMCLMNASAAAD"
     gene            14005..15915
                     /gene="ltrA"
                     /locus_tag="PB779_001420"
     CDS             14005..15915
                     /gene="ltrA"
                     /locus_tag="PB779_001420"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HDE0738950.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
     gene            16019..16243
                     /locus_tag="PB779_001421"
     CDS             16019..16243
                     /locus_tag="PB779_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738951.1"
                     /translation="MSGTYLSIYQWFLTNAQSLVLLAIVVIGLFLGFKREFSKLIGFL
                     VIALIAVGLVFNASGVKDVLLNLFNRIVGA"
     gene            16256..16759
                     /locus_tag="PB779_001422"
     CDS             16256..16759
                     /locus_tag="PB779_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HDE0738952.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKEQIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCNLAEELEGTPIGEAASEIQHAFFNSFEEMVEH
                     VDDIVYYPDCDDMSDVAHYLIVEAGDFGEVPEQLKPYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPE"
     gene            16886..17923
                     /locus_tag="PB779_001423"
     CDS             16886..17923
                     /locus_tag="PB779_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738953.1"
                     /translation="MANIQTSFIDFHNSIRLDVEDNTLLKDYKDQVIDGLKDYLPDDV
                     KFETFLQGSYSVYTGIKSCDEKIDFDIDIAVAFEIDHTVYEDPREPKLWVKEALVEIF
                     PNAQVNLKVPCVTATFTGKKTKKNVHVDVAVYAKEDENYFLAKAKEFSAPENRCWEEA
                     DPKVLKEKINSHVADSDDRKQFRRCIRYLKRWKDNNFNQEYKPTGIGLTINVMDTFLV
                     NKSTDFLTRKVQYNDMECMKQIVSSLKDSFVYEYSETDGWHYRLHAYLPVKPNSDTYS
                     KMTVNQMSDFKNKLSKLYDDLIFAIDTEDEYEATKRLNNQFGEDFLIISEEEVTEKNL
                     RNAFVTDYPSA"
     gene            17938..19635
                     /locus_tag="PB779_001424"
     CDS             17938..19635
                     /locus_tag="PB779_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ThiF family adenylyltransferase"
                     /protein_id="HDE0738954.1"
                     /translation="MDYTDILKEKLTDVVRLFDGNYYGDFSFATIGKLRLKIEIPKHF
                     PLVLPRIYIHNFDHLGLYLPHVEKDGLVCFSSDINYLVDEENSELVLLQCVNKTIKTI
                     EEGLKGLNKNDFRKEFVAFWDKQENQISLFYLCEPALFIKSVDTIMYGKSLVALDKEN
                     ELQLNAASRLFNGEKEDTHELDAYYVPIRNKNNIMPPKNNKAWSKKDILQIVKKNVTG
                     ANKRFFLKLEKRKNRHNVLLILDIPIEEKSNNVIIGFLFTKQSGSIKDYKGTPRTVLV
                     QRHDELYLVNRTSGENYGLGANIAIVGVGSVGSKIAENLGPLGVRKMTLIDNDCFQAE
                     NLYRNSLGADSLKNARSQNNFFKVDLMQEELEKKIPYLCVEVESMNVLDLISMQPGFF
                     KEYDYVFVCIGDTMASLALNNYFSKSSQKVFYSWLEPYGIGGHTLFINYSLNQKGCFN
                     CLYTDSNSKNRCSNRASLVKEGQIFERTLASCRSKFIPYNAIASTECAINAIKLFHKV
                     NQNNMTNSTLFSWIGDGSTFENLGYQYSDRNTFLNGVNKFEERFFSKYCKVCGELDD"
     gene            19628..20089
                     /locus_tag="PB779_001425"
     CDS             19628..20089
                     /locus_tag="PB779_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mov34/MPN/PAD-1 family protein"
                     /protein_id="HDE0738955.1"
                     /translation="MIKFSCDRIVIEVRDEVLKIFEQYRQGKDDLPEAGGVLHGKRLK
                     NGSIIITDITTPQIGDIQKRLLFKKNREIHQQLSNEKWIESNKFSIALGEWHTHPEAV
                     PTPSNVDKKSWRLNVSKQHDDRVYVFIIVGFSDLRMWLLSKKSDIRQAIKL"
     gene            20102..20962
                     /locus_tag="PB779_001426"
     CDS             20102..20962
                     /locus_tag="PB779_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738956.1"
                     /translation="MKSQKNIWWWGFLVGKVMIPALLLISLPMITFFFTNKKMSKEAV
                     IFFFGDQKATFIETLVTSLQLNLNYIFSIIIVISLLNFFKKRNSGKVFNSNGNVYYNY
                     FYFVFWVAATLLGYDKIQIAGIPIHMQYKLVLSGIFSEVLPDIYDDHYDSDGTCKVSI
                     EKENFDDIDGYDSVNLLIIDTYDIKMSELSMENQTYPTIIVRGNSIDGVRKVNRSLIL
                     EIKKTMDEIQKSDFKKVFVASTSNPKNSINIINSSFRFFGRSRRFKLYVLQKDYASNG
                     KYSKKYRIFI"
     gene            21000..21389
                     /locus_tag="PB779_001427"
     CDS             21000..21389
                     /locus_tag="PB779_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDE0738957.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLMFV
                     IVFAHVPPLSMIEGAFLKYLGIPIAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            21373..23823
                     /locus_tag="PB779_001428"
     CDS             21373..23823
                     /locus_tag="PB779_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDE0738958.1"
                     /translation="MMYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKYQVHD
                     NFRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDLQTDALVSM
                     IGDSQIDYRFFIGFKLISTDEEVNLKNLRKSFFSGLQEFVYGVNHHLMGDFVSLSNEE
                     IRRYTKLEKLMESKLARRFKVKRVTPSDLTYLIEHIYGEKGTPFEEYEFQLPKKKLKS
                     ETLVKRYDLLRPTRCLIEEKPRYLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQ
                     QQQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSV
                     DELETTLDQSKESMYKLSYVVRVSAKSVDELKRRCDEVLDFYDDTNVKLVRPFGDMMG
                     LHKEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKP
                     ALASQGVKGSVTNALASAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWK
                     ETLPEIADEINILNLTSKPENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEK
                     FPVLRKAIRTVTQSDQRGLLQVIVELRKEDSPVAENIADHIESFTDYDFAHLLFSDGS
                     ITQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNRE
                     IFKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGL
                     KFAFRSTDIHEIKKTLEFFGLDKEDESNQKCMRDLENGQCLMQDLYGRVGVVQVHPVF
                     EELFHAFDTRPPVQERME"
     gene            23828..25936
                     /locus_tag="PB779_001429"
     CDS             23828..25936
                     /locus_tag="PB779_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDE0738959.1"
                     /translation="MKKKLFRIFGIVLISLVTLIILLSLVGTVAEATGLVDDTVGAGN
                     LYSQYSLGNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEVGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMNMFNLQSNDSQSMGRRVMRKPQMLMNRTLR
                     QLNRNVGRTLAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEIPSDLNKEK
                     PIPNNKKQSRMNLAGRKVGKVLDTQALVKDKTKQVKDGVRNTPTNLKYNFHKGIEKTK
                     KAPEEFKRGLVQEKANRGELREKQQQRRDEKIAEKRKVLNEIGNPHGKRRENVPIKAK
                     VQSQKDRAPKRIVRANSNPEIKRKFASQEIISKGINQSSSKKNSFQQVKRRSTLSKRT
                     NRKVQKSLNPHPKPRSGEKK"
     gene            25933..26937
                     /locus_tag="PB779_001430"
     CDS             25933..26937
                     /locus_tag="PB779_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HDE0738960.1"
                     /translation="MNVKKLSAISLTFLTISFMGILMCVGLLFGEDSEGSSSSGAPPG
                     GSSVSEEVLKHRAMVEKYAKESDITEYVPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNFGGGYLDYVAKNGKKHSFALA
                     ESFSKEKSCGQKIDYPNPIANKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSRPETGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTESYWQQHLIGAGRYK
                     "
     gene            26956..27867
                     /locus_tag="PB779_001431"
     CDS             26956..27867
                     /locus_tag="PB779_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDE0738961.1"
                     /translation="MKIKIERNQKEKSLKKKKERVVSVGKHRKMVLALWLLLSCSLTF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGIENFTKDFSKEYFSWKNNKEAIEKRMNNL
                     EQYLTEEGFALSQDMVRADIPTNSEVQSVKVLDVEKSSEEFVVSFLVEQKITEGKKAQ
                     SISSAYRVTIFEDENRNYIVTSLPTMIAKPDRAKYKTKQVENDSKIDAKTTEEIAEFL
                     ETFFKLYPSASEKELEYYVENDAMRPINIDLKFSKLEDPVYLQNGKKILVSTKIKYLD
                     NVSKTTSYFQYKLILQKNGNWKIIDVK"
BASE COUNT         9576 a         4471 c         5939 g         7929 t
ORIGIN      
        1 ccaaacaaaa gaagtttatt aataaagctt taaacttaaa tatcgatgaa agaaaagagt
       61 tagaatctga gttatttggc aacttaaccc aagtacaggt taacaatcta aaaagagaga
      121 taacagctcg attaatatca aaacttcaat aaaactaatt attcaatcag ccaactcgcc
      181 aagttatcag attggagaga ttagttatgt caatacaaaa gtacacaaca aaaagcggtg
      241 cacgatatag tgtccgcttg tatgttcgta aagatgaaaa tggaaagcaa gaatactatg
      301 taaaaaaagg gtttaaaact gaaaaagaag ccaagttaca cgaagcaaga aaaaaggtcg
      361 agattgaaga taccggctat cataagcctt ctaatgactt gtttataaca gtgtatgaag
      421 aatggttgcc ttcttatagg aatcgtgtac aagaaacgac atatcaacgt acaaaagacc
      481 ttttccgctt gcatatacta ccaaaattcg ggaataagtc catttctaag attactcctg
      541 ttcactgtca gaatgcagtc aatgaatggg ctttaaaatt caagaatatc aaacagctta
      601 agtcttacag ctctcaaata tttgagtatg ccatttttgc agagctatta caccgaaatc
      661 ctatggcaaa tacaaatcta ccaaagcggg aaaagaaaga aaatgaaaat tacttttcat
      721 tagaagaact aaaagctttt tgggatattc tcaataaaga agagccttta aaacatattt
      781 taatcttcca gcttttgatt actactggta tacgtaaagg agagctagct gctcttcatt
      841 ggtctgacat ttattttgaa gaacagctaa tgtatgttag aaagagctat gcaactattc
      901 gaaatgaaga gaagaatgca agaagaaaaa ctgtcaggat tcaaaaaaat acaaaaaata
      961 tatcttccga acgaatatta ccaattgatg cacaaactat tgaaatgtta aaaatctgga
     1021 aaaaagaaca agctcgagag cttttgcagt ttggcataaa tacaaataca aaaaatcaac
     1081 ttatctttac ctatgtaaat gcagacggtg acattaatca acctttgcat gcggactatt
     1141 caaataatat attgaaacgt ttagagaaga aatataaatt taagcacgtt actattcatg
     1201 gattccggca cactcacgct actcttctac tagaaggtgg agcaagtatc aaagaaacac
     1261 aagatcgatt gggtcataaa aatgctgaaa ctacccttaa cacttattct catgttactg
     1321 aaaaagctca acgaaatgcg ttagaaaaat tcattgctta cactggttta taatattgtc
     1381 attacctttc tcattaccag aacgaaaaaa agacaccttc tcgcaatgag aaagtgtctg
     1441 aaatcgttgg tataacaacg attaacgttt tgaaaactgt gaagctttac gtgctttctt
     1501 aagacctggt tttttcttcg tatcattgaa taagtttgaa aagccttgat ttataaaggt
     1561 ttttccgtaa atatattttg ttatatttga ttaaatttga aatgtttgtg ttctaaaatg
     1621 tgttctaatt taaaggcagt atatttcgta ttttatatta aatttttagg ctcattcatt
     1681 ctcaaatcca ttctatttag tcaataaata ttttaaaaag actttataaa caaagatgtt
     1741 caagcgagca tcttattttt ttgtgcctaa tttgaaagga gaacatttca tgtataaaaa
     1801 acaaaaaaag aaattatgtg tattaactat tttgagtttg gctgttcaat caattgtagg
     1861 agcaattgct cctacgattg cttttgctga tgaaattacc catccacaaa cggtaaccgt
     1921 agaactagat ttagcacatc aatatgctgt tgaaggaact tttagtgatg gtcgtccaat
     1981 gtcagaagtc actgttccgc attatgcagt gtacaacggc gttaaacaag atattttctg
     2041 tgttgaacca ggagtcccga tttacaatga gttcactcct ggatatgaga agaacccgtt
     2101 accagatatg tccgataaag ccaaattagt ttccgtttta tggaaaaaag taggtacaga
     2161 tgcagatact catattgtgg cacagaagat gatctggcaa gaagttaatg ggtataccct
     2221 tcactcaata aaacgatcag atggtagtgc cgtaaatatc gcagccattg aggcaaaaat
     2281 caatcaagcc attgccgatt atcagaagaa accaagcttc cataatagta cggctaaaac
     2341 agtattaggg caatcgacta ctgtgacgga tacgaataat ctgaatttgt cagagttcga
     2401 tgaggttgtg gaaaataccg caaacattga ttatcgtgtg aatggcaatc agttgataat
     2461 cagcccaaat gccaattcaa aagaaagtgg tgtgttgacg cttaagaaat ctgctggtac
     2521 cggaacacct gtcgcctata aaaaggctgg ccaacagact ttaatggccg gggcgatcga
     2581 taagccgaac acttatacgg tcaaaattga tgtggaaatg gagggttctt tgaagattaa
     2641 aaaagttgat aaagaatcgg gtgatattat accaggaacg gttttccatt tagactttgg
     2701 aaaaacttta cccgcaaaag acgtgaccac cgataaagaa ggcattgcga ccttagatga
     2761 gattcctcat ggtacaaagg taaccattac tgaaaaatcg gtgccggcgc cttatacgat
     2821 tgataccaca cccatgactg ccacaattaa agcaggtgaa accatttcag tgacttcaaa
     2881 aaatacgcga gaaaaaggtc aaattattct ggataaaacc ggaattgaaa cagggagtga
     2941 tctttggaac gataattact ctttagcggg caatacgttt gccattcgca aggatagccc
     3001 aactggtgaa atcgtccaag aaatgaccac ggatgaaaaa ggtcatgcag aaacaccaaa
     3061 agagattgcc aatgcgttgg aattgggaac ctactatgtg actgaaacca aggctagtca
     3121 tggctttgtg aatactttca aaccagtaaa agtcgaattg aattatgtca atcaaacagt
     3181 ggctcttgtt accagtaacg taaaagggca aaaccaagaa attactggtg aaaccacttt
     3241 gacaaaagaa gacaaagata ccggtcatga aactcaaggg aaagctgagt ttaaaagagc
     3301 tgaatacacc ttgtttactg ttaaggatgg aaaagcggtc aaatggaccg agaactttaa
     3361 accagaattg ttgaagggaa cgaaagcttc tgatgaaacc gtaactttga ctttagatga
     3421 aaagaatcaa gttgccgtta aacacttagc gattaatgag tattactggc aagaaaccaa
     3481 agcgcctgaa ggatatacct tggatgaaac aaagtatcct gtatccatca aaaaggtgga
     3541 tgatagcgaa aaaaatgctg tgattactcg agatgttgcg gcaaaagaac aagtgattcg
     3601 ctttggcttt gatttcttta aatttgctgg atcaactact ggcactgccg aaactggctt
     3661 caatgatcta acctttaaag tgtcgccatt ggaaggaacc aatgaaatca ccggtgccga
     3721 agatgaagcg accacagctt ataacgagca attagggttt gatggttatg gcaagtttga
     3781 aaatcttcct tatggggatt atttacttga agaagtagaa gccccagaag gttttcaaaa
     3841 gattacgcca ttagaaatcc gttctacttt taaagaaaat aaagaggatt ataccaagag
     3901 tgattatatc tttactatta ccgaaaaagg gcaaaagcaa ccgattaaaa cggtaacggt
     3961 cccttatggg aatctaacca atgagaattt ctcagtcagt ttgaaccgtt tgatgcttta
     4021 tgatttgcct gaggaagaag atagcttaac ttctcttgcg acttggaaag aaggagataa
     4081 agaattgact actcttgatt ctaccgagct agtcgataaa ttgagctata atctacatga
     4141 aatcaaagaa gactggtata tcgtagctca agccatcgat gtagatgcta caaaagctgc
     4201 ccaagaaaaa gataaaaaag ccaaaccggt ggcgattgcg gaaacaaccg caactttagc
     4261 gaataaagag aaaacaggaa cttgggagat tctgcataaa ttaactgtcg aacaagtttt
     4321 agacaagacc attgtcttat tcaactatgt gtatgaaagc aaagaagcct atgaagctgg
     4381 tgatgagccg gtagcgaagg atgctagctt gaacaatcaa gcgcaaactg ttaattgtat
     4441 ggtggaacgt catgtttcca tccaaaccaa agcgcactta gaagaaggtt ctcagacctt
     4501 tactcatggt gacgtggtag atatgtttga tgatgtatcc attacccatg atgtactaga
     4561 tggctcaaaa gaagcttttg aaacaattct gtacgcttta tttccagatg gtacaagtaa
     4621 agaaatttgg aaatctggca agattgatta cgaagtgaat gacaaagaat ttaccaaaac
     4681 cgtacttgcg gaaaaagtgg atacaagtaa atatccagaa ggtacaagtt ttaccttcaa
     4741 agaaattaac tatgacaaag atgggaatat caatggaaaa cacaatgaag atttgaaaga
     4801 aaaatctcaa actttaacgc ccaaaaaagt tccgacaaca ccaagtacac cagaacaatc
     4861 tgaaatgcca actgttccaa gtggctctca agaatctagt cctacagtga aggcattccc
     4921 tcaaaccggg gagaaaactt ccaatgtgct actgttcatt ggctttagct tgatctttgc
     4981 gacggctggc tattattttt ggaatcgtcg gaactaaggt gataagatga aacatgtaaa
     5041 tagtagaaaa caatacgcgc gaccgcctcc taaaaaagtg gtcgcgctat ttttgtattc
     5101 aaaactaaca atgaaaagag gaaaaaatat ggaattgaaa tttgttgtac cagatatggt
     5161 cgagacgttc ggaaaactaa catacggtgg tgaaggtgaa gttctatcgg aagggtatgg
     5221 tcgaaatact acaattgttg gtcgaagtta ccatctgttt tcaaataaac aacgggccga
     5281 tgatattgaa gtggtggtag ctgcggaagc cggcgaaaag gattttgacc aagatcaacc
     5341 actaaaagct gtaaatcccc acttaattgc caaaggctat gaaattgaga atcgtgggtt
     5401 taccgattac gtgttgtatg ttgatgattt agtgaaagca taggaggaaa agaagatgag
     5461 attaacagaa ggtattgtcg tagattcagg attaaccttt ggcaagttgc gtttttccgc
     5521 attacgtcga gaagtacgca agcaaaatga ggacggaacg gttagtaacg aggtaaaaga
     5581 acggacctat aatttgaaat cctccgcgca aggtcgaatg atccaagtca gtattccagc
     5641 aaatgtaccc ttacgcgagt ttgcttatga tgcagaggta gagctggtca atccaatcgt
     5701 ggatacggtc gccaattatg tttttcggga aggaaccacc gttaattggt ttatcaaggc
     5761 agatgattta gtcttgaaac gacaactgaa tcaaggaaaa cctacgaacc aaaatgaagg
     5821 aaagaaatag gtgaagaata tggaaattaa tgttgaacat attttagatt gtctcgatca
     5881 atttggcaaa ggtgagctaa cggaggaaca actcactaac gcattaacct atgatgaaaa
     5941 aatgtttctg attatgcatc aagggttact ggaagtaggt aacgatgcca aagaagactt
     6001 tgatgtactg gattggttag gggaagaaga gtctttcttt atggttgtcg aggtaaatga
     6061 aagtttatgt cggcaggcag aatctgtttt ggaagaaatc gatgtggaga tgccggatgc
     6121 catcgaaaga tttttaaaac aattagtgga aacgaaacaa cttcccgtag tagtaaatga
     6181 ctagcataac tttttgaaat tgcccaatga aatcctattg ggctttttcg actggaggtg
     6241 gaaaccatca aaatgtacaa aggacatcgc atacgcgcag gagatcaaca cttgatttat
     6301 cactttgttc ttggctggct aatctttttg ttcattggtt ggatgagcgt cttttattta
     6361 caagaactta gacaatttga tatttctaag gtatcatttt ccactagtga aattggctgg
     6421 tctatgaagg atgtaatctg cttgctagga agtctcgctc tttcaggaag catgatgtta
     6481 ctttatatac acttttttca ggatcattgg cgaagtcttt ggcatcgaca aaagttagct
     6541 cggatgattc tagaaaacca ttggtatgaa gtaaagcaga ctcaaggtga aggttttttc
     6601 aaagatttga atagtagttg gaccaaagag agtatcagtt acttccccaa aatttattat
     6661 cgaatgaaag atggcttact ttctattcgc gttcaaattt cactgggaaa atatcaggat
     6721 cagctattga agttggaaaa taagttagaa agcggactgt attgtgagtt agtagaaaaa
     6781 gaactcaaag actcctatgt ggaatacacc ttgttatacg atatgattgc caatcgaatt
     6841 gggatagaag aaatagtggc agaaaatggg gcgttgcgat tgatgaaaaa tcaagtatgg
     6901 gcgtatgatt ccttgccgca tatgttaatt gctggcggca caggtggtgg gaagacctat
     6961 ttcttactca ccattattca agcactattg aagtcagatg cagaattgtt tatcctcgat
     7021 cccaaaaatg cggacctcgc cgatttaggt acgataatgc ctcacgtata ctcccaaaaa
     7081 gaagaaattt ctgaatgtgt ggaagatttt tacgaacgca tgatagctcg tagtaggtca
     7141 atgaaagaaa tgcccaacta caaaacagga gagaattatg cgtatctcgg acttccgccc
     7201 aactttttaa tctttgatga atacgtggct tatatgggtg cgaatcgttt tcctacaagc
     7261 atcgaataga tgtgaaatgg aagcctattg agattatcaa tagtgacaac taatgttttg
     7321 agagatggaa tgaaagcctt caagttgagc tgaaacatcc ccgctaatac tcctacatgc
     7381 tctaatcaat gaagtagatt ggttttggta tgaagctagg tgaagtcgtc tgaaatctgc
     7441 ctaagtgctt gagcataagg ctgactatag ggcgggcggc tgaaaaagat aactatggta
     7501 agaatgtctg aaaatgactg acgaatctgc gaatgtacgg gtctaaaagg ctgatcttat
     7561 tgaaagatag gaacatacgg acgtatggtg agataccgac aagtaaggtt ccatgatatg
     7621 aaaatcggga tagctaacga agaagctata atttcacagg ctcatagtag atacctaagg
     7681 ttatacatga tagctaaaaa cattggaacg atgtaagcag aaaactatca attaaatgac
     7741 tacttctaga taggtgcata taagtaataa cgaaattgct ttgtttctgt gaaagtaagg
     7801 gcacagtacc gatgaagcgt ctaacaaatg tggagggata gccctaagtc tatttaataa
     7861 caatgaatgt tgaaacagat gaagttcaag gatctggtaa gaacgtggga aaatccgtta
     7921 tggaggtgcc acgcttgaac acaaaaatac gttactggga atattatgat ctacaagaaa
     7981 cattcgatca gctatttact caaagtagaa acgggaaaaa gttttatcaa ttatatgagt
     8041 taatcatttc tgaaaataat attcttttag cataccgtac tatcaaggca aacaaggggt
     8101 cttcgacacc aggaacggat tccttcacaa ttgataacta taaggaaatg aaccaagcag
     8161 agtttatcca tcttattctc agtcatttag aaaattacaa accaaaatcc ataaagcgag
     8221 taatgatacc taaacccaat ggtgagaaac gcccattagg aattccatgc atgattgatc
     8281 gaatgatcca acagatgttc aagcagatac tggagccaat atgtgaagct aagttttatg
     8341 aacatagcta cggtttcaga ccattgagaa gtgcaaagca tgctctaggt cgcattatgt
     8401 atctcataaa catcagtaaa atgcactatg cagtagacat tgatatcaaa ggtttctttg
     8461 ataatgtaaa ccaccgttta ctgataaaac aattatggaa tataggaatt tgtgacaaac
     8521 aagtcttagc tattctttca aaatctctga aatcacccat tcaaggagaa ggtatcccga
     8581 gcaaaggaac gatccaagga ggtatcattt ctccactatt atctaatgtt gttctaaacg
     8641 acttagacca ttgggtctca aagcagtggc atacctttga aacaaagtat ccctatacta
     8701 aaggttacaa taaatttcgt gctctaagag atacaaatct aaagcaaggc tatattgtca
     8761 ggtacgcaga tgactttaaa atcatgacta atgattatcc gacagcatta aaatggttcc
     8821 acgctgtcaa gctttaccta aaagacagac ttaaattaga tatttccaat gagaagtcta
     8881 aaatcgtcaa tttgcgtaaa tgtaagtcgg aatttttagg attcgctatt tgcgtgaaac
     8941 aaaaagggaa aaaatgggtt tgtaattcac gtatttctaa caaaaaaaag gatcagatta
     9001 aagaagagat taaacaaaga atcaaagata ttcaaaagag tcctacagca caaaatgctc
     9061 tcctgtttaa tgctctcgtg ctcggtgttc ataattattt caggtatgcc actcatatta
     9121 atttagattt gaataggatg aactacgttc tttcattcac tacttacaac cgattatcaa
     9181 attgtagtac aagatgttac cccaacaaag cttccccaac ttacaaaaag ttttactcaa
     9241 caacgatgaa aacgtataaa gtagctggag tctatttgta ccctctttgc gacgtatcta
     9301 caaaaacaat ttacggattt aatacggagg atacaccgtt tactccgttt ggtcgtcaaa
     9361 gattggagca caaaagccta cagtctcttg tgttccaaga attaagaaaa ttgatggaat
     9421 cgaaaatacc gaatagaacg gttgagtatt tagatagtag aatatctcgt tactcaatga
     9481 aatcaggcaa gtgtgagatt acaaaacaat ttttgccagc aaaagccgtt cactgtcatc
     9541 actatttgcc aaaaagtctt ggtggagacg acaaattcga taacttgaga attattcata
     9601 aggatatcca tcttctgatc catacaacaa ataaaatgat aatcgatcac tacgtgcatg
     9661 aactgaaact ggtgccagag caaatagcaa aaatcaacct ttatcgaaag atgtgtaatc
     9721 tgcaaaacat tcaatagaaa ataaatagat ggaacgccgt atgaggtgaa agtctcacgt
     9781 acggtgtgga gcgggggaaa agatggagat tatatcaaat tcttacctat cgctatagat
     9841 gttaacgaca aaagaaagtg cggtgatttt gaataagctt aaacaaatcg tgatgttagg
     9901 ccgtcaatct ggtttctttc tgattctagc ttgtcaaagg ccggatgcga aatatctagg
     9961 agatgggatt cgcgatcagt ttaacttccg tgtggctttg ggtcgtatga gtgagcttgg
    10021 gtattccatg atgtttggag aagtcgataa aaattttttt atgaaacgca tcaaaggacg
    10081 aggttatgta gatacagggg gcagtgtgat tagtgagttt tatacgccac ttgtaccaaa
    10141 agggtatgat ttcttaaggg aaattagcaa cattgttgga ttaaccgttc atacggaaag
    10201 agaaaataat agtgtgtagc ctaggaatat caataatcct gggctttttt attgaggtga
    10261 tttatgacat ttttagattt attcgccggg attggtggct ttcgcttagg tatggaacaa
    10321 gccggtcacc agtgtatcgg tttttgtgaa attgatgaat ttgctcggag gagttataaa
    10381 gcaatccatg atacaaggaa ggaggtggaa atgcatgaca tcacaagtgt atcagacgaa
    10441 tttgttcgat ccctcggacc agtggacatc ctttgcggcg gctttccgtg ccaagctttt
    10501 tcaattgcgg gaaagcggca aggattttcc gatactcgag gtactttatt ctttgaaatc
    10561 gctcggttcg ccactcttct ccaacctaag tttctattcc ttgagaacgt ccggggattg
    10621 ctcaatcacg aaggaggggc tacgttcgag acgatcctcc gaacgttgga tggattgggg
    10681 tatgatgtgg aatggcaagt gcttaactca aaggcctacg ttccccaaag ccgtgagcgg
    10741 atcttcctta tcggacattc tcgagatgca tgtaccgaac aagtatttcc tatcattgga
    10801 tcgtcttcaa catctgatca aaacatcaga aacttggtaa atatcaatcc ttccaatcga
    10861 ggaatgggtg gccaagtcta tggttcagat agcgtagcac caaccttgac cggtgatgaa
    10921 ggaattaaaa ttgccttacc ggtaaaggat gggatttctg tagcgggtat gttgtcggga
    10981 aattttgaac aaggcaatag gatttatgag gtaaccggaa cagcccccac tttgtcaacg
    11041 aaacaagggg gaacgaagat tatgattcgg aaaaatgaaa cagaatatca agaggtgaag
    11101 ccaggggaca gtgtgaacct ggcttttcct aattccacaa gtcgccgagg tcgtctggga
    11161 aaacaaagtg tgcatacctt actaacagga gaccaacaag cggtagtcac ggatcagtac
    11221 cagattcgaa agttaacacc tagggagtgc tggcggcttc agggctttcc agattgggct
    11281 tttgatcgag cttctcaagt caattcagat agtcagttgt ataaacaggc cggaaactca
    11341 gtaacagttc cggtcatttt tgatattgct agaagattaa agggggtaaa agcatatgat
    11401 ttatgacgag ttgattggag aaatctactg gatgattggc aagattcagg cagatccgaa
    11461 attggaagaa gaactgtacc ggctcaattt tgatattcgc aaaaacgggg tgaaagtcca
    11521 ggtgattcgt atgtagtgga tgaggaaacg gatgctcgaa tggagctcaa tcaagtcatc
    11581 ggtgaattgg aacgaattgc ggaccttgcc aaagaacctg atatccgcca atacttgttt
    11641 gagataaaag cagagttgga aattgagggt atcaccgcgg agtaataggg aaataaccca
    11701 ctgataggca ctgaccgcgg gggatttgcg aagcagaaat cctccgtggt gctgtgcctg
    11761 ttcatggacg gcggcagccg gccatgatgt ctcacccccc gtatctaaca ggggggtaca
    11821 aaaacacaaa aaacaagcaa gtaaccataa aaaatgcttg ttgtatcaag gatattaagt
    11881 aatttgtata ggtgttaact catttggaaa agttaacacc ttgaatttgg aggtgaaaac
    11941 ttggcgcaac gaaatttaga ttatcggtta ttaaaagaac gacgcaacga atatggcgtt
    12001 tcacaaaata aattagctac tgcttgcgga cttagccgcc catacctaaa tcagatagaa
    12061 aacggtggcg taatcgcctc tacaaagacc atgagaaaaa tttttgatca actggaaagt
    12121 ttcaatcccg atttaccttt aacgttacta tttgactatg taaggattcg ctttcccaca
    12181 acggatgtgc ggaaaattat tcaagaaatt ctccatttga aattcgagta tatgcttcat
    12241 gaagattacg ccttttactc ctatcaagaa caatatgtca tgggcgatat tgtagtgatg
    12301 ttatctcatg aagaagataa aggtgtcctt ttggaattaa aaggtcgtgg ttgccggcag
    12361 tttgaaactt ttttactcgc ccaaaagcgt agctggtacg acttttttga agattgtcta
    12421 aaagccggtg gcgtgatgaa acgcttggat ttagcaatca atgatcgagt ggggctactg
    12481 gatattcctg atttaacgaa aaaatgtcag aaggaagaat gtatctcctt gtttcgtacc
    12541 ttcaaaagtt accgttccgg ggaactgttg aaagctgatg aaaaggatgg tatgggcaat
    12601 accttatata ttggcagcct caaaagcgag gtttattttt gtttgtacga aaaagattat
    12661 gaacaatata tcaagttagg gattccattg gaccagaccg aaacgaaaaa tcgttttgag
    12721 attcggttga aaaatgaccg tgcttattat gcgattcaag atttgttaaa aggtcgtagc
    12781 attgaaagta ccacgttttc cattatcaat cggtatttgc gatttgcgga taaagtagat
    12841 ggaaaacggc gaaccaattg gcccttgaat gaacaatggg gtcgttttat tggacggaat
    12901 cggaaagaga ttcaattaac ttctgaaccg aaaccgtata ccattgaacg aacattaaat
    12961 tggctaggta gacaagtcgc ccctacgtgg aaaatggcta aggagttgga tcgattgaat
    13021 caaacaacgt atatccagga tatggtacag aatgcgcgac tctcggaccg gcataaaaag
    13081 attttggagc aacaaagtat ggcaatcgaa aacttgattg tatgaaaaga ggaattttga
    13141 tggaaattgt aaaagatatg ttattggtac ttggtggcag tatgcttggt gttaccgtga
    13201 tgtgcttgat gaatgcaagt gcagcagcgg attgagcaat ggaaaagaaa ggaaagtgac
    13261 aaaatgaatt tcggacaaaa tttatgtgcg actcgttcct tagtgaaaag ctaaggcact
    13321 aataaaagaa cgaaaaagtt tggttattag gagaactgat aatctgacag gtggaatgat
    13381 gaagtaacgc tctgaaacgc ctgccctgag cctccgacaa gcattgtatg aggaaactca
    13441 gaatgtttga agctcggtaa agacggctga aagataccgt aatagttgat gaacatatat
    13501 cttctatcga aaactatcca gaggtgggta gcgtatccaa caggtcgggg gtctataaaa
    13561 tatctatggt tagaatgttc tataaggaac tgacgaaaca gcgaatgtac gggtctaaat
    13621 ttgaactttg tagaaatgca aaggtacgag aaatcgtagc tggtgtggca aagtaagaat
    13681 ataggttatg aaatgccata taacgttaca ggcggtatca agccagcagg cttatagcta
    13741 gtgacctaag gatatatatg tatagataag attatcggaa cgaggaaagg tattgggttc
    13801 tcatcaagag aataaactga cgaagaacaa taagcagttg aactaatgct gaaaagcaga
    13861 gggcgaacct aagaaattct tgtaatgaga atggaggaat gccctcaagt cgtgtatata
    13921 ttagaaaagt attatgttgt ttcaataagg attacgagta agataaaaaa gctcactcaa
    13981 tttcaagtaa aggagtgaag ccttatgcct aaaaataaaa atgaaacatt gtgtgtagaa
    14041 gatttaagac acgctgaata ttacgaaatg caaaacacct ttgatgattt atatgccaaa
    14101 agtaagaatg gagatatttt cactcatctt atggatatta tcctatcgag agaaaatata
    14161 ttactggcat atcgaaatat caaagcaaat gcaggcagta aaacagcagg aacagacggt
    14221 acaataatta aagatattgg caaattgcca gcagaaacag ttgtcaaaaa agtaagatac
    14281 attgttgcag gcagtccaca tgggtatcga cctaagccag tgaggcgaaa agaaatacca
    14341 aaaccaaatg gtaaaaccag acctctaggt attccttgta tgtgggacag gcttatacaa
    14401 caatgtataa aacaagtatt agaaccaatc tgcgaagcta aatttagtga aaacagctat
    14461 ggttttagac ctaataggtc agttgaaaat gcaataaaag caacctataa ccgcctacaa
    14521 atcagccagc tacattatgt gattgaattt gatattaagg gtttctttga caacgtgaac
    14581 cattccaagc tgataaaaca gatatgggct atgggaatac gggacaagca cttgatattc
    14641 attttaaaaa ggatattaaa agctccaatc aaaatgacta acggtacaat aacatatcca
    14701 gagaaaggaa ctccgcaagg gggaataata tccccactac tagcaaacat tgttcttaat
    14761 gagttagacc attgggtaga aagccaatgg caggaaaatc ctgttacaaa aaactatgtg
    14821 gttcatatca ataaaagcgg tagcccatgt aaaagcaacg cttacaaaga aatgaagaaa
    14881 acaaagttaa aggaaatgta tatggttcgt tatgcagatg attttagagt tttctgccgc
    14941 tacaaggaaa gtgctgaaaa agccaaaata gcaatcactc aatggattga acaacgatta
    15001 aaattggaag tatcacaaga aaaaacaaga attgtaaatg ttagaaaaag atactccgac
    15061 tttcttggtt tcaagattaa aatgataccg agaagaaaga agttagttgt taaatcacat
    15121 ataagtgata aacaattcaa aaaccaaaaa gacaagctgg tatcacaggc aaagaaaatt
    15181 gcttctccct caaaagggaa aacggaatta gaagaaacaa gactttataa ttcaatggta
    15241 ttaggtatgc aaaattatta tcagattgca acgaatgtaa atctggattg tatgaaactg
    15301 aatagagctg taatggctat cttcactaac agattaggta caaacaaaag gggcagattg
    15361 agaaaaacag gcagacaact tacgacaaag gaggcaacaa gatatggtaa atctaaaatg
    15421 cttcggtatg ttgctggcga gggcgaacct attttccctg ttggatatat ccaacacaga
    15481 aaaccaatgg caaaggtgta tttagcgaat tgctacactc tagagggaag aaaatttatc
    15541 cacaccaatc taagtgttga taaattactg atgtaccagt taatgaaatt atctttggaa
    15601 aatcgcacaa tagaatacgc agacaatcga atttcgctat tttctgctca acatggaaaa
    15661 tgtgctataa ctctggaaga atttcaacaa gctaatgaaa tacattgtca tcatattgta
    15721 ccaactggag ctggtggaaa tgacgattat aaaaatctta ttttggtaaa agaggcggta
    15781 caccgtctaa tacacgctaa aacagaagaa acaatacaaa aatatatagc tctattgaag
    15841 ctaaataaag tccagctcat aagactaaat aaatatagag tattagctgg caatcaagaa
    15901 ttaaacttga tataggtcta ctacataaat acttttcaat ataaacacga tggaacgcgg
    15961 agtgcggtga aagtcgcacg ctccgtgtga atggggggaa aagtttgaga tatttataat
    16021 atcaggaact tacctatcca tatatcaatg gtttttaacc aatgctcaat ctttagtctt
    16081 actagcgatt gtggtcattg gtttgttttt aggatttaaa cgggagtttt ccaaactgat
    16141 tggcttcttg gtgattgctt tgattgcggt aggtctggtc tttaatgctt ctggtgtgaa
    16201 ggatgtccta ctcaatttgt ttaaccgaat tgtcggtgcc tgagggggaa tcacaatgga
    16261 acagatgcgt gtttatattg cgaaccttgg aaaatacaat gaaggtgagt tggtgggggc
    16321 atggtttacc ccacctgtcg attttgatga agtgaaagaa cagattggat taaatgacga
    16381 atatgaagag tacgcgattc atgattatga actgcctttt gagattgatg agtatacgcc
    16441 aattgaagag attaatcggt tgtgtaactt agcggaggaa ctagaaggaa cgccaattgg
    16501 tgaagctgct tctgagattc aacacgcttt cttcaattct ttcgaggaaa tggtagagca
    16561 tgtggatgat attgtctatt atccagattg cgatgatatg agtgatgtgg cgcattactt
    16621 gattgtagaa gctggtgatt ttggcgaagt tccagaacaa ttgaagccgt atattgattt
    16681 tgatgcttgc ggtcgagatt tggagattgg aggaaattat ttggttacta gtcgtggagt
    16741 ttttgagtat ccagaatgaa tcaaacacta tatatagtgt ttgattagta tatgtaagca
    16801 aaaaaacaca atatatagag tgcaaactga agggtaatgt gatataatat ttgccgaaga
    16861 aatatttttg aaatgaggta atattatggc aaatattcaa acaagtttta ttgatttcca
    16921 taattcaatt agattggacg tagaagacaa tacgctactt aaggactata aagaccaagt
    16981 aattgatgga ttaaaagatt acttacctga tgatgtgaag tttgaaactt ttttacaggg
    17041 aagctattct gtttataccg gaataaaaag ctgtgatgaa aaaattgatt ttgacatcga
    17101 tattgcagtt gctttcgaaa ttgatcatac tgtttatgaa gatccaaggg agcctaaact
    17161 gtgggtaaaa gaggcgctag ttgaaatttt tcctaatgct caagttaatt taaaagtacc
    17221 ttgtgtaact gctacattta ctggaaaaaa gacaaaaaaa aatgtgcacg ttgatgttgc
    17281 ggtttatgct aaagaagatg aaaattattt cttagcaaaa gcaaaagaat tcagtgctcc
    17341 cgaaaaccga tgctgggagg aagcggatcc caaagtatta aaagagaaaa ttaatagtca
    17401 tgtagcagat tcagatgatc gaaaacaatt tcgaagatgt attcgctatt taaaaagatg
    17461 gaaagataac aattttaacc aagaatataa accaacagga attggactta caattaatgt
    17521 gatggatacg ttcctagtta ataagtccac tgatttttta actagaaaag ttcagtataa
    17581 tgatatggaa tgtatgaagc agattgtttc ttcgctgaaa gattcatttg tgtatgagta
    17641 cagtgaaaca gatggttggc attatcgtct acatgcatat cttccagtga agcctaacag
    17701 tgacacctat tcaaaaatga cagtgaatca gatgagtgat tttaaaaaca aactttctaa
    17761 attatatgat gatttgattt tcgctatcga tactgaagat gagtatgaag ctacaaaacg
    17821 attaaataat caatttgggg aggatttttt aattatttca gaagaagaag ttacagaaaa
    17881 aaacttaaga aatgcatttg ttacagacta tccgagtgct taggttggtg ttaaagattg
    17941 gattatactg atattttaaa agaaaagcta acagatgttg tgcgtttatt cgatggtaat
    18001 tactatgggg atttttcatt tgctacaatt ggaaagttgc gtttaaaaat tgaaatacca
    18061 aaacattttc cattggtact tcctaggatt tacattcata attttgatca tttaggactt
    18121 tacctaccac atgtagaaaa agatgggttg gtatgttttt cttcagatat aaattattta
    18181 gtagatgaag aaaattcaga attggtttta ttgcagtgtg ttaataaaac tataaaaaca
    18241 attgaggaag gtttgaaagg gttaaataaa aatgattttc gaaaagagtt tgttgctttt
    18301 tgggacaaac aagagaatca aatttcgtta ttctaccttt gtgaaccagc gttgtttatc
    18361 aagtcagttg atacaataat gtacggtaag tctttggttg ctttggataa agagaacgaa
    18421 ttacaattaa atgcagcgag tagattgttt aatggagaga aagaagatac tcatgaatta
    18481 gatgcatact atgttccaat tagaaacaag aataatatta tgcccccgaa gaataataaa
    18541 gcatggtcaa agaaggatat tttacaaata gtaaaaaaaa atgtaacagg tgcaaataaa
    18601 agattttttt taaaacttga aaaaagaaag aatagacata atgttttact tattctagat
    18661 atcccaattg aagaaaagtc aaataatgtc ataattggat ttctttttac aaaacaatct
    18721 ggatctataa aagattataa gggtacgcct aggactgtat tagttcagcg tcatgatgaa
    18781 ttatatttgg tgaatagaac gagcggagaa aactatggat tgggtgctaa tatagctatt
    18841 gttggggtag ggtcagttgg cagtaaaatt gctgaaaatc ttggtccatt aggtgtgaga
    18901 aagatgacac tcatagacaa tgattgtttt caagctgaaa atttgtatcg aaattcactt
    18961 ggtgcagata gtttaaaaaa tgcccgatct cagaataatt tttttaaagt tgatttaatg
    19021 caggaggagc tcgaaaaaaa aatcccatac ctttgtgttg aagtggagtc aatgaacgtt
    19081 ttagacttaa ttagtatgca acctggtttt ttcaaggaat atgactatgt ttttgtttgc
    19141 ataggagata caatggcaag cctggcttta aataattatt tttccaaaag tagtcaaaaa
    19201 gttttctatt cttggctgga gccatatggc attgggggac acactctatt tataaattat
    19261 tctctaaatc aaaaaggttg tttcaattgt ctttatacag attcaaactc taaaaatagg
    19321 tgttcaaata gagcttctct ggtaaaagaa ggacaaattt ttgaaaggac tttagcgagt
    19381 tgccgctcaa aatttatacc atataatgct attgcctcga cggaatgtgc aattaatgca
    19441 ataaaacttt tccataaagt caatcaaaat aatatgacca atagtactct tttttcatgg
    19501 ataggagatg ggagtacttt tgagaattta ggatatcaat atagcgacag aaatactttt
    19561 cttaatggag tcaataagtt tgaagaaaga ttcttttcta aatattgcaa agtatgtggg
    19621 gagttagatg attaaatttt cgtgtgaccg tattgtcatt gaagtaaggg atgaagttct
    19681 taagatattt gaacaatatc ggcagggaaa ggatgacttg cctgaagctg gaggagttct
    19741 tcatggaaaa agacttaaga atgggagcat aataattacc gatataacaa cacctcaaat
    19801 aggagatata caaaaaagat tactctttaa aaaaaaccga gaaattcatc aacagctttc
    19861 taatgagaaa tggatagaat caaataagtt ttctattgca ttgggagaat ggcatactca
    19921 tcctgaagct gtaccaactc catcaaatgt tgataagaaa agctggagac tgaacgtgag
    19981 caagcaacat gatgatagag tttatgtttt tattatcgtt ggattttctg atttgagaat
    20041 gtggttactg tcaaaaaaat cagatattag gcaggctata aaactataaa ggagtgatta
    20101 ggtgaaatca caaaagaata tttggtggtg ggggttttta gtaggaaagg taatgatacc
    20161 agcccttctc ttaatttctc taccgatgat tacttttttc tttaccaata aaaaaatgag
    20221 taaagaagcc gtgatttttt tctttggaga ccaaaaagct acctttattg aaacgttagt
    20281 aacatctctt cagcttaatt tgaattacat tttttcaatt attattgtta tatcgttatt
    20341 gaattttttt aaaaaaagaa attcaggaaa ggtgtttaac tctaatggaa atgtgtacta
    20401 caactatttt tattttgtat tttgggtagc agcaacttta cttggttatg ataaaattca
    20461 gattgcagga attcctatac acatgcaata taagttggtt ttgagtggaa ttttttctga
    20521 ggtgttgcca gatatatacg atgatcatta cgacagtgat ggaacatgta aagtaagcat
    20581 tgaaaaagaa aatttcgatg acatcgatgg atatgactct gtgaacttac tgattattga
    20641 tacttacgat ataaaaatga gtgaattatc tatggaaaat caaacatatc ctacgataat
    20701 tgttagaggg aattcaatag atggagttcg taaagttaat agatctttaa tcttggaaat
    20761 aaaaaaaaca atggatgaaa ttcaaaaaag tgactttaaa aaagtatttg ttgcttcaac
    20821 atctaatcca aaaaatagta tcaatattat taattcatcg tttagatttt tcggtcgatc
    20881 acgtaggttt aaactttatg ttcttcaaaa ggattatgca agcaatggaa agtatagtaa
    20941 gaaatataga atttttattt aagaaggaat ttttccttct ttttattttg gaggaaacta
    21001 tgaaaaaaat aaaaagctac accagtattt gggcagttga aaaagtcatt tatgcgatta
    21061 atgactttca gctgcctttt cctgtgacct ttaaccagat ggcttggttt gttttatcct
    21121 tgatgtttgt cattgtattt gcccatgtgc ctccgctatc catgatagag ggggcttttt
    21181 taaaatactt gggcattccg atagcggtca cttggttcat gtcgcaaaag acctttgacg
    21241 gtaagaaacc attgggattt ttacgatcct ttatcagcta tcacttacgg tttaaggtca
    21301 cttttgcagg aaagaaagtt aaagaacaga agaaacgatg ggacgaacca atcaccttgg
    21361 taaggagtgt gaattatgta cccgattaag tatattgaaa ataatcttgt ctttaaccaa
    21421 gaaggcgagt gttttgctta ctatgaatta gtgccttaca attactcctt tttgtcacct
    21481 gaacagaagt atcaagtaca tgataacttt cgccaattaa ttgcgcaaaa tcgtgaaggt
    21541 aagatccatg ccttacaaat tgccacagaa agtagtattc gtgccacaca agaacgttcg
    21601 aaaaaggaaa ttaccggtag actcaaagaa gtagcaaagc aacgaattga tttacagaca
    21661 gatgcattag tatccatgat tggcgatagt cagattgatt atcgcttctt tattggcttt
    21721 aaactgattt cgacagatga agaggtcaat ctaaagaatc tcaggaaatc tttcttttct
    21781 ggacttcaag aatttgtcta tggagtgaat catcatttga tgggtgattt tgtttcctta
    21841 tccaatgaag aaattcgtcg ctataccaag cttgaaaaac taatggaaag taaattggct
    21901 cgaagattta aagtcaaacg agtaacgccg agtgacttga cgtatttaat tgaacatatc
    21961 tatggtgaaa aaggcacacc gtttgaagaa tatgaattcc agctaccaaa gaaaaagctg
    22021 aaatcagaaa cgctggtgaa acgttacgac ttattacgtc ccactcgttg tttgattgaa
    22081 gaaaagcctc ggtacttacg gatggaacat gaaaatcatg agtcttatgt agcgtactta
    22141 acaattaata ccattgtagg ggaaatggag tttccttcct cggaactttt ctattaccag
    22201 caacaacaat ttacgtttcc gattgatact tcaatgaatg tggaaattgt gacgaataaa
    22261 aaggccctag ctaccgttcg taataagaaa aaggaattaa aagatttaga caaccatgcc
    22321 tatcaatctg ataatgaaac gaactccaat gtattagatg ctttggattc cgtggatgaa
    22381 ttggaaacca ccttggatca gtcgaaagaa tccatgtata aactaagcta tgtggttcga
    22441 gtgagtgcta aatcagtgga tgaattaaaa cgccgctgtg atgaagtgct cgatttttat
    22501 gacgatacca atgtaaaact agtccggccc tttggcgata tgatgggtct acacaaagaa
    22561 ttcttaccct caagtaagcg atacatgaat gactatattc aatatgttac gtctgacttt
    22621 ttggcgggac ttggttttgg ggctactcaa atgctaggag aattagaagg catttacttt
    22681 ggctataacg tagatacggg gcgcaatgtt tacctgaaac cggcattggc atcacaaggg
    22741 gtcaaaggct cagtaaccaa tgctttggca tctgctttcc ttggttcgtt aggtgggggg
    22801 aaatctttta gcaacaatct cttagtctat tatgccgtcc tttttggtgg gcaagctgtg
    22861 attgtcgatc caaaaggaga aagaggcggt tggaaagaaa cgttgccaga aattgcggat
    22921 gaaattaata ttcttaactt gaccagtaag ccagaaaatc aaggcttact tgatccctat
    22981 gtgattatga agaaaaagaa agactcagaa agtttggcga ttgatatcct gaccttttta
    23041 acagggattt ccagtcggga tggggagaag ttccctgtgt tacgcaaagc cattcgaacg
    23101 gttacccaaa gtgatcagcg aggattatta caagtaatcg ttgaattgcg taaagaggac
    23161 tcaccagtcg cggaaaatat cgcggatcac atcgagtcct ttaccgatta tgattttgcc
    23221 catttgcttt tctcagatgg ttcgattacc cagtcgatta gtttagataa gcagttaaat
    23281 atcattcaag tagcggattt ggttttacca gatgcagaaa ccacttttga agaatatacc
    23341 accatggaat tgctgagtgt ttccatgcta attgttattt ccacttttgc cttggacttt
    23401 atccatagca accgagaaat tttcaagatt gtggacctgg atgaggcttg gagttttctt
    23461 caagtagctc aaggaaaaac gttatcgaat aaattagtgc gtgctggtcg ggccatgaat
    23521 gccggtgttt acttcgtcac gcaaaacagt gatgacttgt tggatgaacg tttgaagaat
    23581 aatattgggc taaagtttgc atttcgcagt accgatattc atgaaatcaa gaaaaccttg
    23641 gaattctttg gattagataa agaagatgaa agtaatcaaa aatgcatgcg agatttggaa
    23701 aatgggcaat gcttgatgca ggatttgtat ggtcgagtag gtgtggtcca agttcatcca
    23761 gtctttgaag aacttttcca tgcttttgat acccgtccgc cagttcaaga gagaatggag
    23821 tgaggagatg aaaaagaaac tttttcgtat ctttggaatt gttttaatca gtttggtcac
    23881 tctgataata cttttgagct tagttggaac ggtagctgag gcaacaggtc tggttgatga
    23941 tacagttgga gccggaaatc tttattccca atattcactt ggtaactatc agttggattt
    24001 ctttgtggat agttcgtggg attggctgcc ttggaattgg ggtgatggcc tagggaagag
    24061 cgtaatgtat ggactttatg ccattactaa ttttatttgg acagttagtc tctacttatc
    24121 aaatgccacg ggctacgtgg ttcaagaagc ctataagctg gatttcattt cagatacggc
    24181 tgaaagtatt gggaagaata tccaaacctt agccggcatt accgaaaatg gactccagac
    24241 ctcgggcttt tactttgggt ttctattatt gatgatttta gctctaggag tttatgtggc
    24301 gtatacagga ttattaaaac gagaaactac caaagcagtc cgggctgtca ttaattttgt
    24361 gatgattttt ctactttcgg gttcgttcat tgcgtatgcg cccacctata tcacaaaaat
    24421 caatgatttt agctcagatg tcagcgaagc ggctcttagc cttggaaccg agattgtcgt
    24481 gccgaattca gaaagccaag gaaaggacag tgtggattta atccgagata gcttgttttc
    24541 cattcaagtc caacaaccgt ggttactctt gcaatttgat gattccaata tagaagaagt
    24601 tggcgaagat cgtgttaaca aaatcctgtc tgtaagtcca gatgaaaata aaggcaagga
    24661 tcgggaagaa gcggtcaaag cggagattga agataatgac aatgcgaatc tcagtattac
    24721 caagaccatg aaccgcttag ggaccgtggt ctttttggtg ttgttcaata ttggcatatc
    24781 cttctttgtc tttctcctaa cagggattat gttgttctcg caaattctct ttattatctt
    24841 tgcgatgttt ttgccgatta gtttcttatt gtccatgttg ccgacttatg agagtttggg
    24901 caagaaggcg attattcgct tgttcaatac gattatgatg cgagcaggag ttactttggt
    24961 gattacgact gcatttagca tctccacgat gtttttcaat atttcggcaa cctatccatt
    25021 tttcatggtt gcttttctgc aaattgtgac ctttgccggt atctatttca aattgggcga
    25081 cattatgaat atgttcaatc tccagagtaa tgatagccaa tcaatgggaa gacgggtcat
    25141 gcgaaaaccg caaatgttaa tgaatcgaac attgcggcaa ctcaatcgaa atgtgggacg
    25201 gactttggct tttggtggtg gtgcagcagt tggaaataag ttggcaaagg aacaatcaaa
    25261 atccaaattt aagccatccg gttcttctct acgaaagaat tcacgattac cgaacgatca
    25321 cgagatacca tctgacttga ataaggaaaa gccaattcca aataataaga aacaatcccg
    25381 aatgaatttg gccgggagaa aagtcggcaa ggttctggat acccaagctt tggtgaaaga
    25441 taagaccaaa caagtaaagg atggagtacg gaatacgcca accaacttga aatacaactt
    25501 ccataaagga attgaaaaaa cgaaaaaagc accggaagag tttaagcgag gactggtcca
    25561 agaaaaagca aatcgaggag agttgcgaga aaaacaacaa caacgtagag acgaaaaaat
    25621 agctgaaaag cgcaaagtat tgaacgaaat agggaatcct catgggaaaa gaagggaaaa
    25681 tgttccgata aaagcaaagg tccaatctca aaaggataga gcaccaaagc ggattgtgag
    25741 agcaaattcg aatcccgaaa tcaaacgaaa attcgctagc caagaaatca tttcaaaagg
    25801 aataaaccaa tcctcaagta agaaaaattc ttttcaacaa gtgaaacggc ggtctactct
    25861 gtccaaacga accaatcgaa aagtacaaaa aagtttgaac cctcatccca aaccaaggtc
    25921 aggtgagaaa aaatgaacgt aaagaaatta agtgccattt cgttaacttt cctaacaatc
    25981 tcttttatgg gtatcttgat gtgtgtgggc ttattgtttg gtgaagacag tgaaggaagt
    26041 agtagttcag gtgctcctcc tggggggagt agtgtctcag aagaggtttt gaaacaccgt
    26101 gcaatggtgg aaaaatatgc caaagaatcg gatataacag agtatgttcc gattctttta
    26161 gcgattattc aagtggaatc tggtggcaca atggaagatg tgatgcaaag ttctgagtca
    26221 gccggtttac caccgaattc attaagtacc gaggcatcca tcaaacaagg atgtctctat
    26281 tttgcgtctt tggttaagcg ttccaaagaa ttaggttgtg atcaagatag tatcattcag
    26341 gcctataact ttggcggtgg ttatttggac tatgtggcaa aaaacgggaa gaagcatagt
    26401 tttgctttag ctgaatcttt ttcaaaggaa aaatcttgcg gtcaaaaaat cgattaccct
    26461 aatcccatcg cgaataagga aaatggtgga tggcgctata actatggcaa tatgttttat
    26521 tgcttattgg tgaagcaata cctaactaca acacagtttg acgataaaac agtccaaggg
    26581 atttttgacg aggcgtttaa gtatgaagga acggcttatg tatttggtgg gtcaagaccc
    26641 gaaacaggat ttgattgtag tggcttgact caatggtgtt atgccaaagt tggtctgaaa
    26701 cttcctcggg tggctcaaga tcagtatgat gccatgaccc atattgacct aaaagatgcc
    26761 aaaccagggg atttggtttt ctttcattcg acttatgatg ccggtactta tgtgacccat
    26821 gtcggtattt atgcagggga gaatcgcatg tttcatgcag gagatccagt aggctggacg
    26881 aatctaacag aaagctattg gcagcagcat cttatcggtg ctggacggta caaataagag
    26941 aaaagaggaa aaagaatgaa gataaaaatt gaacggaatc aaaaggaaaa gagcctaaaa
    27001 aagaaaaaag aacgagtcgt atccgtgggt aagcatcgaa aaatggtgct tgccctttgg
    27061 cttttattat cttgtagtct tacttttggc gtttataaaa atttcaccgc cattgatcaa
    27121 catacaactc atgaaaaagt ggttattaaa gagaaagtag tgaatacttc tggtattgaa
    27181 aactttacga aggatttttc gaaagaatat ttttcgtgga aaaataacaa agaagcaatt
    27241 gaaaagagaa tgaacaacct cgaacagtac cttacagaag aaggtttcgc tttaagtcaa
    27301 gatatggttc gagcagatat tcccactaat tccgaagttc agtcagtaaa agtcttagat
    27361 gttgaaaaga gctcggagga atttgtcgtt tcatttttag tggagcaaaa gattacagag
    27421 ggaaaaaagg cacaatcgat ttcttctgca taccgagtga cgatctttga agatgaaaac
    27481 aggaattata tagtaacgag tttgccaact atgattgcaa aacctgatag ggcaaaatac
    27541 aagacaaaac aagtagaaaa tgattcgaaa attgatgcca aaactacaga agaaatcgct
    27601 gagtttttgg aaacgttctt taaattatat ccatcagctt ctgaaaaaga attggagtat
    27661 tatgttgaaa atgatgcgat gcgaccaatc aatattgact taaagttttc gaagttagag
    27721 gatccagttt acctacaaaa cggaaaaaaa attctagtga gtacaaagat aaaatacctt
    27781 gataatgtat caaaaaccac tagctacttt cagtacaaat taatattaca aaaaaatgga
    27841 aactggaaaa tcattgatgt taaataataa tgactcaatc taaatttatg agaagttata
    27901 agtagtttaa cttat
//
LOCUS       DAMEEU010000033        27614 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.034, whole genome shotgun sequence.
ACCESSION   DAMEEU010000033 DAMEEU010000000
VERSION     DAMEEU010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27614
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.034"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(644..1624)
                     /locus_tag="PB779_001432"
     CDS             complement(644..1624)
                     /locus_tag="PB779_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HDE0738962.1"
                     /translation="MLFLKKEDIIKSFSMREAIDADKKALSLYSAGKASVPLRTNIDV
                     PKSNGQSLYMPAYVEGGEGALGVKIVSVYPENIKKNLPSVPATMIVLDPETGMVSACL
                     DGTYLTQLRTGAVQGAATELLAREDAKIGALIGTGGQAQSQLEAMLTVRKLEEVRIFD
                     IDFERASQFAEKMMQQFSVTMRPTKTSQECVEGADIITSVTTSKRATFSAEWVKKGAH
                     INGVGAYTPEMCEIPREIIKAADVVIFDTMDGVLKEAGDFISPLQDGYIQRDSYHGEL
                     GQLINEELIGRTSGEQITIFKTVGSAVLDVVVATEIVKKAKENNLGKLIF"
     gene            complement(1637..2515)
                     /locus_tag="PB779_001433"
     CDS             complement(1637..2515)
                     /locus_tag="PB779_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HDE0738963.1"
                     /translation="MIRNILLTLIVAINLYFIIYFLRDLFKNKQNFKEEPGDMRLLPF
                     TSFIIFFLSTFGVSDFAIGTVLYPKLKWVSMKKLPGTLNTQCVVPVAVMALSYITAIN
                     VGIKTLAVCIICQIIGAYLGPRFVVKLPEKTIKLFVGIGLVIAALLIFAGQMNWIPSN
                     GTASELYGGKLILAGFLLFVYGALNNIGIGSYALTMVTVYLLGLNPVAAFPIMMGACT
                     FSVPIGSVQFIKFNEYSRKITLFTSTFGVLGVLVAVFLVKSLDTYILKWIVILVLLYS
                     AYTMLGSQLKKVTAAN"
     gene            complement(2531..3331)
                     /locus_tag="PB779_001434"
     CDS             complement(2531..3331)
                     /locus_tag="PB779_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HDE0738964.1"
                     /translation="METIIQIMKKYDFSEMETRVYTTLLEKGNLTGYEVSKISGVPRS
                     KVYNILEKLLKKNLIVVNKSEPKLYHAISANEFLEKLEKSVKNDLSFLTKNLGMIKEK
                     DEEEMLWKVDGIEYVLDKVEHLVKNAKESLLIQVWHENFTDSLLKALQQAEKRVDKFV
                     LILFSSTHEYDLPLEKYYIHGFETDKLADFGARWINIVADEQEVVFGTINEELQSTDV
                     TWTKNHAMVNLAKEYVKHDAYTLKVIAESPEELKAKYGEGFEGIRKIY"
     gene            complement(3606..3755)
                     /locus_tag="PB779_001435"
     CDS             complement(3606..3755)
                     /locus_tag="PB779_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0738965.1"
                     /translation="MKKKVIPYCPKPRNAFERGLFKYFEGKKGQDHKEENQKKKSKKR
                     SEYIF"
     gene            4723..5049
                     /locus_tag="PB779_001436"
     CDS             4723..5049
                     /locus_tag="PB779_001436"
                     /inference="COORDINATES: protein motif:HMM:NF013698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0738966.1"
                     /translation="MFKIFRKNCCGLDVHKTWIYACIGITDANGRTVYKQARFSSFTK
                     GLNELAEWLAKYNCKDVCLESSGKFWIPVFNILEKTCFVTLAHPKYTKPQKGNKTDRK
                     DAKMDL"
     gene            5030..5965
                     /locus_tag="PB779_001437"
     CDS             5030..5965
                     /locus_tag="PB779_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDE0738967.1"
                     /translation="MQKWICDLFMCDMIKPSFIPGLEIRQLRDLMRYRTKLTNMKTSE
                     KNRALNCLTVSNLKLDDVFSDVFGKSSTSIIQYLLEHPGESFDVRPFIHARCKTPVEE
                     IQAAVEGAISVPQAIKLRQCLNHINEIEKHREEINLEIQALAEPFSPVLELLRTIPGL
                     DTQPITAIAILSEIGPDMSVFPTSKHFISWAGCCPRNDRSARRTKSTRISRAGQSLKP
                     LLVQIANALLRSKEHPEFKNRYRRIKANRGHKKAIIAICKMLLTAIWNVLSKVEPYSA
                     KGYLEPKPAKEEKVLTQSQALDLLRKRGYTIIDSA"
     gene            6594..6845
                     /locus_tag="PB779_001438"
     CDS             6594..6845
                     /locus_tag="PB779_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lrp/AsnC ligand binding domain-containing
                     protein"
                     /protein_id="HDE0738968.1"
                     /translation="MKSNQKSGFYTFIKAISSVLECDCIIGPYSMLIKMGFPSTESLD
                     SFINDLSKFGRTNTQIVFSTLVSLMVYQFWNVYHALLLK"
     gene            7387..7545
                     /locus_tag="PB779_001439"
     CDS             7387..7545
                     /locus_tag="PB779_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738969.1"
                     /translation="MNKKQACEFLGIDNNTLDKWIRVYNFPVIKIDGVVRFDVEDIKD
                     FMNTFKKN"
     gene            7617..8843
                     /locus_tag="PB779_001440"
     CDS             7617..8843
                     /locus_tag="PB779_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0738970.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGIASEKYQKVFPTRQLAIKA
                     EREMKKKIETVLREENANSLELKGKIKFKDFYESKWLPRYELGQTTRSNRAPSNVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILCYIEFNRTTKIIQCITAPKKMALEEKRIREGNQALSSEELTDWIEAVNNDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFNKNTVRLKYALDKYQRKTHTKGWKDTV
                     IQAPEVVMTLLREWKSAQAEQLLKLKIIQTPDQYLFTYSKPSGEVNCPVHADYLNYRI
                     NAIKKRHPELAQLSPHKLRHTYATIAREGGANMNQISNALTHSDISTTKIYVNTPDVV
                     DKSVFEAFQKGLNKCD"
     gene            complement(8932..9324)
                     /gene="rpsI"
                     /locus_tag="PB779_001441"
     CDS             complement(8932..9324)
                     /gene="rpsI"
                     /locus_tag="PB779_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HDE0738971.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(9340..9783)
                     /gene="rplM"
                     /locus_tag="PB779_001442"
     CDS             complement(9340..9783)
                     /gene="rplM"
                     /locus_tag="PB779_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HDE0738972.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(10302..10769)
                     /locus_tag="PB779_001443"
     CDS             complement(10302..10769)
                     /locus_tag="PB779_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDE0738973.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(10889..12427)
                     /locus_tag="PB779_001444"
     CDS             complement(10889..12427)
                     /locus_tag="PB779_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HDE0738974.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            12507..13193
                     /locus_tag="PB779_001445"
     CDS             12507..13193
                     /locus_tag="PB779_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HDE0738975.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(13394..13921)
                     /gene="msrA"
                     /locus_tag="PB779_001446"
     CDS             complement(13394..13921)
                     /gene="msrA"
                     /locus_tag="PB779_001446"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDE0738976.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(14005..14682)
                     /gene="pgmB"
                     /locus_tag="PB779_001447"
     CDS             complement(14005..14682)
                     /gene="pgmB"
                     /locus_tag="PB779_001447"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDE0738977.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(14679..15807)
                     /locus_tag="PB779_001448"
                     /pseudo
     CDS             complement(14679..15807)
                     /locus_tag="PB779_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
     gene            complement(15807..17990)
                     /locus_tag="PB779_001449"
     CDS             complement(15807..17990)
                     /locus_tag="PB779_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDE0738978.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(17987..19012)
                     /locus_tag="PB779_001450"
     CDS             complement(17987..19012)
                     /locus_tag="PB779_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0738979.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTANRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(19057..19884)
                     /locus_tag="PB779_001451"
     CDS             complement(19057..19884)
                     /locus_tag="PB779_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HDE0738980.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(19881..20948)
                     /locus_tag="PB779_001452"
     CDS             complement(19881..20948)
                     /locus_tag="PB779_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HDE0738981.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(20974..21810)
                     /locus_tag="PB779_001453"
     CDS             complement(20974..21810)
                     /locus_tag="PB779_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0738982.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(21807..22676)
                     /locus_tag="PB779_001454"
     CDS             complement(21807..22676)
                     /locus_tag="PB779_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0738983.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(22746..24029)
                     /locus_tag="PB779_001455"
     CDS             complement(22746..24029)
                     /locus_tag="PB779_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HDE0738984.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(24043..25728)
                     /locus_tag="PB779_001456"
     CDS             complement(24043..25728)
                     /locus_tag="PB779_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HDE0738985.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            26003..27028
                     /locus_tag="PB779_001457"
     CDS             26003..27028
                     /locus_tag="PB779_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0738986.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
BASE COUNT         8030 a         5733 c         4884 g         8967 t
ORIGIN      
        1 taaaaaatat gcggcgcaca gaacgcgccg catatcggac taagttttat tcaaatttgt
       61 cttcgccaac acaatttgac gaagagcctt ttctttcagg aagacttcgg taatttttag
      121 gagttctacc tattctttta accgtttatt ctctttttct aagcgtgtaa tttcatttct
      181 gcgaatggat ttcatgactt cctctaccga gaaaagtacg ttatccatat ttttcaactt
      241 cttgaactca tcaatacacg ctattagagc gagcttctag ctatagacta acttctttaa
      301 cagaaaaccc ttcttccgtt accagtttta cagcggtaat tttaaatatt tcatcaaatg
      361 aacgtcttgg cataatccag atcttcgctt tctcttaatt tggtgtcaat tttagtataa
      421 cccgtccaac ttatttttta actaagtgcc cggtttttct tgacaactcc acccaaaagt
      481 tagatttttt ggtctaagtt ttagggtcgc ttcattacta gaattcaaca agagatgttt
      541 tttattttat ttaaattatg gggtcagttt ccatttgatt acaaacttct ttgttttctt
      601 tttttaaacg caataataaa ggttttaatt tcagcctttt taattagaaa atcaattttc
      661 ccaaattatt ttctttagct ttcttaacga tttctgtcgc aactaccaca tctaatacag
      721 ccgaaccaac tgttttgaag atcgtgattt gttctccact tgtccgaccg atcaattctt
      781 cattgatcag ttggcctagt tccccatgat agctgtctct ttgaatatac ccatcttgca
      841 gcggtgaaat gaagtcccca gcttctttta gaacaccgtc catggtatca aaaataacaa
      901 catctgcggc tttgattatt tctcgtggaa tttcacacat ttccggtgtg taagcaccga
      961 ctccattgat gtgcgcacct tttttgaccc actcagcaga gaatgtcgca cgttttgaag
     1021 tggtcacact tgtaatgatg tctgctcctt caacgcattc ttgactggtt tttgttgggc
     1081 gcatcgttac agaaaattgt tgcatcattt tttcagcaaa ttggctggca cgctcaaaat
     1141 caatatcaaa aatccgaact tcttctaatt tacgaacggt caacattgct tctaattgtg
     1201 actgtgcttg tccgccggtt ccaatcagcg cgccaatttt agcatcttct cttgcaagaa
     1261 gttctgttgc tgctccttga acagcgcctg ttcttaattg tgtcaaataa gtaccatcca
     1321 aacaagcgga taccataccc gtttctggat ccaatacgat catcgttgct ggtacacttg
     1381 gtaagttttt cttgatgttt tcaggataca cggaaacgat tttgacacct agcgcgcctt
     1441 cgccaccttc tacataagca ggcatatata agctttgtcc gttgcttttt ggcacatcga
     1501 tattggtgcg aagaggcaca cttgcctttc ctgctgaata caatgacagt gcttttttgt
     1561 ccgcatcgat ggcttctctc attgaaaaac ttttgataat atcttctttt ttaagaaata
     1621 acatttgaat cgctccttaa ttagctgctg taactttttt taattgactg cccaacatcg
     1681 tatatgcact gtatagtaag accaaaatca cgatccattt caggatatag gtatctaaag
     1741 atttgactag gaatacagcg accaataccc ccaatacacc gaaggttgaa gtaaaaagtg
     1801 tgatttttct gctgtattca ttaaatttaa tgaattgaac actgccgatc ggtactgaga
     1861 aggtacaagc ccccatcata ataggaaagg ctgcaactgg attcaagcct agcaagtaga
     1921 cagttaccat cgttaacgca taagaaccaa tgccgatatt gttcaatgca ccatagacaa
     1981 agagtaaaaa tcctgccaag attaattttc cgccatacaa ttcactggct gttccgtttg
     2041 atggaatcca gttcatttgt cctgcaaaaa tcaacaatgc agcaatgacc aatcctatgc
     2101 cgacaaacag tttgatcgtt ttctctggta acttcacgac aaatcttggt cctaaatatg
     2161 caccgataat ttggcagata atacaaacag ctagtgtctt gatccctacg ttgatggcag
     2221 tgatgtaaga caatgccatg acggctaccg gtactacaca ttgggtattc aacgttccgg
     2281 gtagtttttt catgctgacc catttcaact ttggataaag gacggttccg atagcaaagt
     2341 cggaaacgcc aaatgttgaa agaaagaaga tgataaatga cgtgaagggc aacagacgca
     2401 tatcccctgg ttcttctttg aaattttgtt tgtttttgaa aaggtctctt agaaagtaaa
     2461 taataaaata tagattgatt gcgacaatta gtgtcagcaa aatattccga atcataaaaa
     2521 attcctccta ctagtaaatc tttctgattc cctcaaagcc ctcaccatat tttgctttaa
     2581 gttcttcagg agattctgca atcactttta gtgtatatgc atcatgtttg acatattctt
     2641 ttgctagatt gaccatggcg tggttttttg tccaagtgac atcggttgat tgcagttctt
     2701 cgttaatggt accaaacacg acttcttgct catcggcgac gatgttgatc catcttgctc
     2761 caaagtcagc aagtttgtct gtttcaaaac catgaatata atacttttct aagggaagat
     2821 catattcatg ggtagaactg aataaaatca gtacaaactt atcaactctt ttttcagctt
     2881 gctgcaatgc ctttagtagt gaatccgtga aattctcatg ccaaacttga atgagcaaac
     2941 tttcttttgc gtttttcacc aaatgctcta ctttatccag aacatactcg ataccatcaa
     3001 ctttccacag catttcttct tcatcttttt ctttgatcat ccctagattc ttggtaagaa
     3061 aagaaagatc atttttaaca cttttttcta atttctctaa aaactcattt gccgagatgg
     3121 catgataaag tttaggttct gatttattaa cgacaatcaa attctttttt aatagttttt
     3181 ccaaaatatt atatactttc gagcgtggca cacctgagat tttacttact tcatatcctg
     3241 taagattacc tttttctaat agtgtggtat acactcttgt ctccatctct gaaaaatcat
     3301 attttttcat gatttgaata atcgtttcca ttgattaatc ctcactttat ttttagtagc
     3361 tactacggta acaactataa attctttttg attatctgtc aagagttagt tcaataacac
     3421 acatataata attagcttaa aaacaatctt tttattaaaa agaaacatta taatatgaat
     3481 gtttgtgaaa aaataataca acttagtcat tctttacaac gatttataga aaaacaacct
     3541 ctttaaatat aaaaggtacg ggttactgat tacttgtaaa tctttacgtt ccagttttat
     3601 tctttctaaa aaatatactc acttcttttc ttagacttct ttttttgatt ctcctcttta
     3661 tggtcttgtc cttttttgcc ttcaaaatat ttaaataaac ccctttcaaa agcatttcta
     3721 ggttttggac aataaggaat gacttttttc ttcatataaa tacctcattt aactatttga
     3781 tatcatcaca ttatcaaaaa aaataggttt tttattaaaa ctatcttgac ctttcgggag
     3841 atttcactgt gatttatttt tattcccata cttttttcgt tggtcacttt cgtataccta
     3901 atctaagcga tcatcggcga cggtgctttt acaacgaatg gcaggacaaa acaaggggcg
     3961 gaaaaacttt tttgcctatt tcataaaaaa ctttttccta cagcaatccc ttgttttgtc
     4021 ctaccacacg ttgtgaaccc aaagcacgcc gacgaacgct tagctatacg aaaatgacct
     4081 ccaaaaacaa aaaagtgagg tgaatagaaa caaaaagaaa ttgaaatctc ccaaaatgtc
     4141 gtccgcctcg gagacaactt gctgctgaaa atggttggtt aattcattta agtattaaat
     4201 aagataaatc atcaaattaa tcggaaaaat agcatgattg gccttatcaa aaataaactg
     4261 taaaaactta tatttctatg agtggtggaa caatgctaat accaaattaa tttatcgatt
     4321 acccacctgc acaaaccaaa gatagcatta ttaggaaacg aatcaatcag cgaatccagc
     4381 attataatga ggatactaaa aataaagttt tcataattat aaatccgcct tcctacgaaa
     4441 ggcaccaatg aggtgatgaa aaccttagag cgctttcttt ctttttttat tccgtgttac
     4501 cctttccttg caggtccctg gtacactaca gaacccgagg aggtgagtgg cggggctgta
     4561 tagcggcaac cccgcataat tatatggtgt cggtcatccg ttaaggcatc aatgaatggc
     4621 gcaaacccgt agcccgtaaa cttatctctt ccgaagttga ctcgatttcg ccggatgacc
     4681 agtccctacc aaacctgtac tattttttta caggaggttg ctatgttcaa aatctttcgt
     4741 aaaaattgtt gtggcttgga tgtccacaaa acgtggatct atgcgtgtat cggaatcaca
     4801 gatgcgaatg gtcgtacagt gtataagcaa gctcgcttct cttcctttac aaaaggtctc
     4861 aatgaattag ctgaatggct tgctaaatac aactgtaagg atgtgtgttt ggaatcttcc
     4921 ggtaaatttt ggattcctgt ttttaatatt cttgaaaaaa cttgttttgt cacactggct
     4981 catccgaagt acaccaaacc ccagaaagga aataaaacag atcgcaaaga tgcaaaaatg
     5041 gatttgtgat ctctttatgt gcgacatgat caaacccagt tttattcctg gtcttgaaat
     5101 ccgccagctt cgtgatctaa tgcgttatcg gacgaaactg accaacatga aaacaagtga
     5161 aaagaatcgt gctttaaact gcttaaccgt ttctaatctg aaactagatg atgtttttag
     5221 tgatgtgttc ggaaaatcat ccacttctat catccaatac ttgttagaac atcccggtga
     5281 atcatttgat gttcgaccat ttatccatgc ccgttgtaaa actcccgttg aagaaatcca
     5341 agcggcagtt gagggggcga tttctgtacc tcaagcgatt aagcttcgcc aatgcctcaa
     5401 ccatattaac gagattgaga agcatcgaga agagatcaat ctagagattc aagctcttgc
     5461 agaacccttc tcccctgttt tggaactact tcgtaccata ccgggcttag acactcagcc
     5521 aataacagcg attgcgattc tttcagaaat aggaccggat atgtccgtgt ttccaacttc
     5581 gaaacacttt atttcttggg ctggatgctg tccaagaaac gatcgcagtg cccgacgaac
     5641 aaaatcaaca cgtatctctc gtgcagggca gtcgttgaaa ccgctacttg tacagattgc
     5701 caatgctctt ctcagatcca aagaacatcc agaatttaaa aatcgctatc gtagaatcaa
     5761 agcgaatcgt ggacacaaga aagctatcat tgctatttgt aagatgctcc tgaccgctat
     5821 ctggaatgtc ttatcaaagg tggaacccta ttctgctaaa ggatatctgg agccaaaacc
     5881 tgcgaaagaa gagaaagttc tgacgcaatc ccaagctctg gaccttttaa gaaaacgcgg
     5941 atataccatt atagatagtg cttaaaccaa agttacgttg attcttccta aatagactcg
     6001 ttgtcttcca tttcaaaaat tttgaaaacg gtaggcttat ttagtgtacc gttcttcagg
     6061 tatcttcaaa tagatttatt ttcaaactta tttcctttct tcttttactc tcctatagct
     6121 tagcatttaa gtgggcactc gtgtcacctt gctagatagc tatgaatgcc gtaataagcc
     6181 tcctagtata taggcagact gccaattata actgattcaa tccacattat gataaaatcc
     6241 accttttcgt ttcatatgtg ttgaaatatc acatatgtca aaagtgcacg agtcttttca
     6301 ttcagtgctt tgtaaatact caaaattatt ccttttcact ttaaaaaaaa gataattagt
     6361 acaaaatcag aaatgaggaa agtattagga tggactagaa aggagttgtt gaatttgttg
     6421 caacagattg gtcatttatc aattaaaaat taggtgaagt tttattcatc actgcagctg
     6481 ctgtttccca gagaataaaa cgtctagaag aaactggtca gttactgtat tatcaagcag
     6541 caattgacta cgaacaagct tgattactaa ccaaagcgtt tatccacctg ttgattaaat
     6601 caaatcaaaa atcaggtttt tatacgttca taaaagcaat ctccagtgta ctcgaatgtg
     6661 actgtatcat aggtccttat tcgatgttaa tcaaaatggg gtttccttct accgaatcat
     6721 tggacagttt tatcaatgat ttatcaaagt ttggacgaac caacacccaa atcgttttct
     6781 cgactcttgt ttccttaatg gtttatcagt tctggaatgt ttatcatgcg cttttattaa
     6841 aatagaaaag agcttttttc atgcgacaaa gcagtgatca tttattggca catgcaatct
     6901 ttgtggatcc attttttgaa aatacgatat ttagttttga cccaaaaatc tttaaatacg
     6961 tatttgataa tttatcttaa caaccagata attttattca gcaccgtatt atctatattg
     7021 aattctcgga atcaagataa atttttttcc gtttttgttt cttttttaat cttcttcttg
     7081 ttattaatag tgattaggat gatattccta tattgatctt tgataattag atataatttt
     7141 tgaataacgt tccctgctat tcgagctaga aatacaagta cgccatgacc tagttagcga
     7201 caactactta gagatttctt ttgttctggg acaacaaaat gccatgacaa tagcagtaaa
     7261 taatgatact tccgtaaggc tcgccgtaaa ctggggagag gtgaaattcc tatgtgctta
     7321 cccaaagcgg ttcaaaaatt ttaaactatt attttaggag atgattttat aaaatcgaaa
     7381 gcctacttga ataaaaaaca agcctgtgaa tttctaggaa ttgataataa tactttagat
     7441 aagtggattc gtgtatataa ttttccagta ataaaaattg atggcgtagt tcgctttgac
     7501 gtagaggata tcaaagattt catgaataca ttcaaaaaaa attgaaattt tcttctcgtc
     7561 acatatacta taaatagcga aatgtactgc cttacttttt aaaggagtga ggaagtttgc
     7621 ctacaaagct ttcaaatggg aaatataaaa ctaatctgag gtatccaaaa aaattcagag
     7681 aaatcactgg aattgcatca gagaagtatc aaaaagtatt tccaactagg caattagcta
     7741 ttaaggccga aagggaaatg aaaaagaaga ttgaaacagt tttaagagag gagaatgcaa
     7801 actcactaga attgaaagga aaaataaaat ttaaagattt ttatgaatca aaatggcttc
     7861 ctagatatga actaggtcaa actactaggt caaacagggc tccaagtaat gtaacaatta
     7921 gtaatactaa ggatatattc cgattgcaca tccttccaat gtttggtgaa tatgcaatga
     7981 attatctgaa ttcaaatact gagataatat cagatgaatt aacaaagaaa tcgaaagaat
     8041 acgcaaatat aaaaattatc aaaggctatg ttcgctctat gtttgatatt gccgaaatac
     8101 tatgttatat cgaattcaac cgaactacca aaattattca atgtattacc gcgcctaaga
     8161 aaatggcttt agaagaaaaa aggataaggg aagggaatca agcattatca tcagaagagc
     8221 tgactgattg gatagaagca gtaaacaatg acttaaataa tcacttgctt acacttcacg
     8281 attacacact tttcatgctt accttatatc taggtgatag aaaaagtgag acttatgctc
     8341 tgcaatggaa atatattgat tttaataaaa atacggttcg tctcaaatat gctttagata
     8401 aatatcaaag aaagacacat acaaaaggtt ggaaagacac cgttattcag gcaccagaag
     8461 ttgtgatgac attattaaga gaatggaaat cagctcaggc tgaacaattg ttgaaactaa
     8521 aaattataca aacacctgac cagtacctct ttacctattc caaaccttct ggagaagtaa
     8581 attgtcctgt tcacgctgac tacttaaact atcgaatcaa tgcaataaaa aaaaggcatc
     8641 ctgaattggc tcaattatct ccacacaaac ttcgtcatac ctatgcaact atagctaggg
     8701 aaggtggagc aaatatgaat caaatctcta atgctttaac gcactcggat atttctacta
     8761 caaaaatata cgtgaacaca cctgacgtag ttgataaatc tgtttttgaa gcatttcaaa
     8821 aaggattgaa taagtgtgat taacatgtgt tctcaaatgt gttcttatta taaaaaaaga
     8881 cactttccaa ataattgaaa agtgtcctga aatattgata taaaaagaat attaacgttt
     8941 tgagaattgt gaagctttac gagctttttt aagacctggt tttttacgtt cgaccatacg
     9001 tgcgtcacga gtaagtaagc cagcacgttt aagagctaaa cggaagtcag gatcaacttc
     9061 tagcaatgca cgagcgatac catgacggat agctcctgat tgtccagcgt atcctccgcc
     9121 gtttacgtta acaaatacgt catatgcgcc ttttgtttca gtaacagcga aaggttgatt
     9181 gattacttca cgcaagtcag catgtggaat gtattcttca acatcttttt tatttacagt
     9241 aattttgcca gttcctggta ctagacgtac gcgagcaact gcgtttttac gacggcctgt
     9301 gccgatatat tgaacttgtg ccaatgaaat tccctcctat tagattaagt ttgtgatgtc
     9361 taaaacttct ggttgttgtg ctgcatgtgg atgttctgct ccaccgtata cgttcaattt
     9421 tgtaaattgt ttgcggccta aagtgttttt aggaagcata ccttttacag aagtttcgat
     9481 caaacgacga gaatttttag cacgcaattc gccagcagtg attgatttca atcctcctgg
     9541 gtagttgctg tgacggtaat aaattttgtc agtcgctttt ttacctgtta atttcacttt
     9601 gtctgcattg atgacgatga cgaaatcgcc agtatccaaa tgaggtgtga aagttggttt
     9661 atttttacca cgtagtacag atgcaacaac tgttgaaaga cgtcccaatg gaacatcagt
     9721 tgcgtctact acataccatt tacgttctac ttcgcctggt ttggccatat atgttgtacg
     9781 cacgttattt tcctccaatt taagttctga tgtttgacat acacttcgag tttccggggc
     9841 tctttgtggg gcaaacaata ccatttaaca tattacccgc taatctagtc aatgtcaacg
     9901 tttttctgct tgattgaaaa atttatatga aactttactt cttttctttc ttttatataa
     9961 aagggtcgtt tcctgtcaaa atgaaaaaca aaaagaggct gtgacaaaag tcttgtcaca
    10021 accccttatt ttgaataaac ggtgttctcc tgccaactcc tcggtcacaa gtcacaatat
    10081 ccataaaaca taagaagctg ttttttaaaa ttgtttcttg tgactcggag ctgaacggca
    10141 ggcttacaac ctcttggtaa acggtgttca atcagctgac cctcggtatt agctcaaaaa
    10201 acggcaaaat atgaggaact attttgacgt ttgtttctct aatactcagg tcaaaacgct
    10261 gatttcacaa cctctttttc ggtcaagttc aacaacagtt tttacgcgtc gatctctggc
    10321 gctttgccca aatgagcttg gatcatccag atacgttttt ctgtggctgt tttgaattcg
    10381 ataaagatat cttgtgttgg atcgtcgcct tcttctccag aaacttcgat tcctttttgg
    10441 taaagatctg ctagataacg atagcctgca acaagtgttt ccaaacgttc tggaatagta
    10501 cgatcccagc ggccaatttc atcagggatt tttgtgttat ctgcaaattc acgcaatgta
    10561 gaataaggtg aaccgtctaa tgtgatcaag cgttcggata cttcatctaa ctgagcgttc
    10621 aaatcatcca tgaactcatc catcattggg tgcaatgtaa ggaaacctgg tcctctcatg
    10681 taccaatgtg tttggtgaac aacaacagac atttggctta gatctgcaac taattgattt
    10741 aatacttctt tggtttgttg gaatttcatc tttcttgcct cctaacattt tcttacactt
    10801 aaaataatag tagactttca atgaaaagta caacaaaatc atttacctga gaacgatttt
    10861 cagttcgctt ttttatccgt aaagccaatc atttttcaga atcagctaat tcttctcgca
    10921 gttgagcaaa ttgctgataa gtctgtgcta aatgcttttg tgtcgaaaca aataatggat
    10981 agattttctg atatttttta tgatcagttt cttgtactcc aacttgctct ttcaattcta
    11041 tcaattcctg tgcttcactg atactttgga tctttccgat gcttctccag cctaaaatca
    11101 cagctcctaa tgcggatgct tctgtgacag tagggaaaac aagcgggtaa cccagtacat
    11161 cagccatcat ctgacgaaaa atcggagatt gagcaaaccc gcctgtagca cggatctctg
    11221 tgagctgatt ttcctggcaa actcctttta aaatccgata aaggttgaga cagatccctt
    11281 ctagaatcgc cttcatcatt tctttttctg tatgttgccg ctgtaaaccg ataaaactgc
    11341 caaacgcatc tgcgtcccaa agcggtgctc gctcaccaag taaataggga tgaaaaatca
    11401 gaccattggc acccgctggc acaaaagcga tagccgaaag cagtgcatca tatggatttt
    11461 ctcctttttc tttagcagat tgaacgactt cctgtaaaaa tgtatgccct gcccaatcaa
    11521 agatgccagc accattgcta gtcgctcctc ccactaccca atgtttctga tccagaacat
    11581 aacaaaacgt ctccatttct ggatggaact gaggctgagt agtaataaaa cgaagtgctc
    11641 cgctcgttcc tacggtcaaa gcggcgatcg tatcaccaaa agcacctaac cctagattag
    11701 aaagcggccc gtctgcccct cccaaaacaa atgatatatc atttggcaaa cctagttctg
    11761 ctgctgtttt tgatggtaga cctgttactt gataggtgga aggaaagact tgcggcaatt
    11821 gctctattcg aatgttcaag tagtcaagca cttcttctgc ccattggaat tcatggatat
    11881 caaaatatcc agttcctgaa gctgttccgt agtcgctgat cagttcgcca aacaatctat
    11941 aaaagatata gtctttgata ccgacaaaat aagcagtttt tttgaataat tcaggttggc
    12001 tgttttgcag ccacttgatt ttgttcaatg gtgtcattgg atgaatcggc gtcccagtct
    12061 gccgataaaa ttctttgcca agcacggtat atttcagttt ttctgcttcg tccgctgctc
    12121 ggttatctgc ccaagtgatc attcgagata acggtgtttt ctcttcatcc aacaatatca
    12181 ggccatgcat cgcagaggag aaggagacaa attgaatgat tgtgtctgaa ggcaactgtt
    12241 taattacttc ttttataacg gtgcagacac cttgaaagat caattcctga tcttgttctg
    12301 ccatcccttg tgtttcttgg atcaaagggt agcgaaaata agcggatgct gcttcttggg
    12361 cttcatctgt gaaagcaact gctttggttt gtgtggttcc gatatctaat ccgattgaaa
    12421 cgttcatttt ttcacctcaa attttatgta tgtacaaaaa tttagtttaa gcttgcgtat
    12481 cttggttttg aaaaggggga gatggcgtgt tactttattt tatcattggt tgctgtatcg
    12541 gatcattttt atgtttaacc gcccagcgga ttccgttagg tcactctatt atttatccta
    12601 gatctcattg tgtcaaatgc tgtcgttcgc tttcttggta tgaattgatt ccgattctct
    12661 cgatcatcgt ccaacgattt cgctgccgct attgcaggtg tcggttgccc ttctactatt
    12721 tgttggcaga agccttatgt ggtggtcttt ttgcctggtt ctttactttt tcttccgcaa
    12781 gaaatttttc gacgttcata tggatgcttt cggctttgct attttcgttg atggatttat
    12841 tttacttcat ggtccattct cacacgctat tctgttcttg ggcaatttta tggatttttt
    12901 ggttgcaggc cggcgtcttc caatggcaaa gtgtgctgtt aacgtttatc gtaggcggtg
    12961 tgtgccttcg ctatggtcaa tcctatctcg gagctggcga tactctgttg atgctttctt
    13021 ggagtggtgg cttgtctcta gaagagttgc ttcagatctt gtttcttgct agtctgtttg
    13081 gaatatccgt tttttctgtt tactttatct gtcataaaaa aaagttggaa aagctgcctt
    13141 tcattccttt tttgagcagt gcgttgctga ttgtccttca tcttaggtat tgaaaaaagg
    13201 ttgtgacaaa cgacttgtca caacctctga tatatagtgt tctcttacca aatccttgtg
    13261 acttggagct aggcgacagg ttcacaacct ctccactaaa tggtgttcaa tcagctgacc
    13321 ctcagtatta gctcaaaatg ctggttttac aacctctgat atacggtgtt ccataagtag
    13381 ctttttcggc ttcttatttc ttgacgcccc aatgtcgacg aaggaaacct gcacgtccag
    13441 aaccttctcg ataaagattg taatggagct tgtttttctt gtaataatcc tgatggtaat
    13501 cttctgcagg ataaaattcg cttcttggtt cgatttttgt cacgattggc ttatcgaatc
    13561 gcccgctgtc ttgcaatgct tgttttgaac gctctgcaat atttcgttct tcttcatcat
    13621 tatagtagat cactggacga taagaatcac cgcgatcagc gaactgtcct aatgcgtcag
    13681 tcggatcggt ttgctgccaa tagatttcca ccaactgatc ataagaaata acttctggat
    13741 catattcgat ctctactgct tctgtatgcc ctgttgtgcc tgttgttact tgttcataag
    13801 ttggatttgg tacatgcccg ccagtataac cggatgtcac agaaatgatc cctggctgct
    13861 cttcaaatgg tttgaccata caccaaaagc atccgcctgc gaaaactgct ttttttgtca
    13921 tataaaatcc cccttttttc tcatcatacc ttgatttcca aaaggaggat aacgttttgc
    13981 ttgtgacaga aaaaacggaa actattatat acgtgatacg gcttctgata aatgccaaaa
    14041 cgaacgtact tgatcaaaaa cggttaaatc aggaatcaca tattcagcag aaggaagatt
    14101 tatgttttca cctattccca atacatgcat gttaccagcc aaagctgctt gacaaccagc
    14161 ttctgaatct tcaatgacca agcatgcatt tggcggtaca ttcaattgct gtgctccttt
    14221 gagaaaaact tctggatcag gttttgcttt tgatacttgc gtgccgtcaa taaggacatc
    14281 aaaataactt gtcaaattcg ttttttctaa aatgaggcgt gcatttttgc ttgctgatcc
    14341 caatccgatc ttgatgtttg tttttttcaa gtactcaaga acagctattg caccaggcaa
    14401 aacggatgtt tcatccattt tttgaatcgc ttgaagatat agattgtttt tttgctcagc
    14461 aaaggctgat ttctcttttt ctgagaattt ctgttccatt tttccaaatg acagcaatcg
    14521 ctctagtgac tcggttctgg atattccttt cagttgctcg ttttctttct cagtgaatgg
    14581 aatggacagc tggttagcta aaaccagcca cgcttcgtaa tgataacgag ctgtgtctac
    14641 aagaacgcca tctaaatcga atagtgctgc tttgattttc atcgattacc tccttgaaaa
    14701 tgaacgactt gaagtaaaga tgcgatgttt ttagctgtgc gatgaagatt atcagtggct
    14761 tgctgtaaag cttcttgtaa aggcacagct gcaggaagga tcggaaaaac ggccgaaatg
    14821 ccaacatctg ctgctttttc gcttccttta ccaacacttc cgcaaatagc tatcacagga
    14881 acgccctctg gtactcttct agcaatccca actggcgctt ttccttttag actttgtcca
    14941 tctagacgtc cttcgcctac gattacgagg tctgcttgct gtacccgtat cgaactccag
    15001 taaatccaat acgtagtcga tgccagagac tattttccct gaagcaaatg ctaacagtcc
    15061 tgcacccatt ccaccaccag cactactgcc cgatgcctcg attacttgag gggcaaatct
    15121 catataaaaa tcatgcatgg cttggtcagc cactgctaat tcattttctt tcaagccttt
    15181 ttgtggtccg aaaacaaaag aagcgccttc ttttccgcat aaaagattag taacatcagt
    15241 aatgacagtg attttggctt taatcagctc aataggcacg ttcgttttat caactgtagc
    15301 aattttacct agattttctc ccagtgcttc tactttttga ttatcttgat cgtaaaaagc
    15361 ataacctaga ccttctgcca tgccgatgcc gccatcgttg gtactacttc cgccaacgcc
    15421 gatgatgatg tgtcgaacac cttgttgcaa caattgtcgt atcagttctc ctactcctcg
    15481 cgtggataac ctaagtggct gttgttggtt tagtgggaca tctttcaatc cgacgatttc
    15541 tgccatttca aaaatcgcag tttgaccgtc tgaagcgtac tggatttctt tgtttttgcc
    15601 aaatgcatta gtaacgactg ctgtttgccg cttcaacctt aaactgtctg ctaatgatga
    15661 aaccgttcct tctcctccat cgcctatagg tagcagatca tattcagcct gaacaaaaac
    15721 ttcttgaaaa cctgattgaa tggcttgtgc tgcctctaag gctgtcagac tttctttgaa
    15781 agaatctggc gcaatcagaa tacgcattat tttcccctcc gttccaagat cagttctttt
    15841 tccagctggt attggtctcc attgacaaaa ataggtaatg tttctttcgt ctcttttttt
    15901 attactattt gtttttttgt caaaacaaat agcaacctgt gatttttcca aataaaagga
    15961 aaagaaattt tttcccatgc tgaaggaagt cttggagaaa tagaaagagt tccattcgtt
    16021 actgtaatac ctgaaaaacc aaatataact gctagccata gtgctcctaa tgaagcagca
    16081 tgaattccgt catctgatga atgcggatct ggtcctaaat caatcaggca cgcttcttgg
    16141 aataaatgat acgcccattc catttcttgg atacggcaag cctctatggc gtgaatcgct
    16201 ttactcaacg atgagtcgtg gattgttttg ttttcatagt aatgcaaatt cttagaaacg
    16261 attggttgag aaaaatactc aggtaataag tataacagca tgacaagatc tgcttgcttg
    16321 ctgacttgga gttcatttac ttcgctacgg gcataatcaa gtaaaataga ctggctgcca
    16381 ggacgttctt tgtaagtggt caaatcaata actggcttac tgagatacgt gtcatcttgc
    16441 ggaatcagct gttctttgtt aggcactggc aaatataact tatctaaaaa attttgacat
    16501 tctttcaaaa aaagcggatc gccagcttga tatttaacag ctaaggccac attataatgc
    16561 gccagatagt tcgtatatgc attattgtcg atatattctg tgtattcatc tggaccaatg
    16621 actctgtgta tctctaaatg atcatcgact tttacagctc tgctcagcca aaaagctgct
    16681 gtttcatgaa tgagcgtttt tccctttgtt tctaaaaacg attgatcctc tgttgcttgg
    16741 acatactctt gaacggcata agcaaggtct gcactgatat gatgttctgc ggcagctgaa
    16801 gcaacttctt gtcttgttcc ggttttgata ttcaatgcag caaatttggg tgtctcttcc
    16861 tgaccagtgt gtgcgctttc ccatgggaaa agtgcacctt gatagtgata atctcttgct
    16921 ttttgccgtg cgccttctaa tcgatcataa cggtacagca gcaaattctt tgctacttca
    16981 ggaaactgat ataaaaagaa aggcaggata aaaatttccg tatcccagaa aacatgccct
    17041 ttataacctt cgccagttag tcccttcgcc cctacactaa cacttggatc attgcgggga
    17101 gtcataatct gtaaatggta agcagcgaag tccatcgcta actgatcgaa agaagaatcg
    17161 ccttggatcg ttatccgatg ctgatgccaa aaatctgtcc aataagacat cgactgctct
    17221 aaaatttctg tataactaac gcttttctgg gcttgggcaa tacttttctt aaacgggtct
    17281 gtttgctgaa gagaggtaga gagcacgatg atcttctcca gcgtaaagga cgtatttttt
    17341 ctgatctttt ctgaaaagga agcggtgatc cggcgatttt ttgcttggaa tacacctgct
    17401 ttattgaatt tagctgcaat cccaatatca attttacttt ctgttgtctg gtaggatgca
    17461 ctgatcaaat cgtcaccaaa tactcgcagt tctttttcaa ccaactgctg tgtaccaaaa
    17521 ttggtttgct gtccatcgat acccgttttc acatctactt ggcagtcttc ggtcaacggc
    17581 ttgatgacca ctttcagggc tgcctgatgg agattatttt gatcagcaac acgacaagta
    17641 atgacttcca ctttttttcc ttgagcagtt tcaatgagcg catagcgttt aagctctccc
    17701 atttctaaat ctagtgcccg ctcgtatgca agaactttca tcgtctcaag agaaaaatgt
    17761 tcaccgtcga tttttatttc ccatctgatg acatctggga gattcactaa ctcggctgat
    17821 tctgctccta aaggtcggtt atatacacca gctgcaaaca ttccccttac ttgattccga
    17881 tagtcttcct cctggcttcc tctgatacca aaaaatccat ttccaatggt catctgactc
    17941 gcatacttat tgatatactc taaatcaaac tgtttttctt ctactttcat aaggtaataa
    18001 cttctcctgt ttctgccgaa cgatataaat tttccaccag attctggatg acatatcctt
    18061 gccagccatc tgcaatcatc tgagtctggt caccgagcgc ccgattcaca aaatgagcca
    18121 tacttagttc atgtgggtca ttaactggcg tggtcttttg taaggaaacc agctttccat
    18181 ctacatcttc gaatagttcg cctggataca gattagcacc tgcctgatcg ccacaaaaag
    18241 ccacattcag tttgtcttct ctgatattca aagcaaacga agtattcagt tggatgatct
    18301 tgccgttttc taattccagt gtgccaaaaa ttgcatcttc tactgtgaat ttgcttggat
    18361 cccatttccc gaatttccct gaattttttt tcgtaccaat tttttggaag ctgtacgccc
    18421 gaacgctttt tactttagga aatccagtaa tatacatcgc tgtatcaagc atgtgaatgc
    18481 cataatcgat caaaggcccg cctccttgaa gttctttgtc gataaacgtt ccccagcctg
    18541 gaacaccaga ccgacgaagc gcattcgctt ctacgtaata aatatccccg agaacatcaa
    18601 gatgattctt gatcattgtt gcttcgtcag aaaaacgatg ctggaatcca taagccaaaa
    18661 tctgcccgtt tttatcggct gtctctgcca tctttcttgc ttgatcagct gtcatagctg
    18721 gtggtttctc gcacatcact gaagcattag cttcgagggc agccaataca tgttcgaagt
    18781 gaaagcgatt ggctgtacag acactcacga tatcgggaga aatctcattc agcatttgtg
    18841 taactgatgt atacgcatga gaaaatcctg tacgtcggca aaagtcttct gctcgctggc
    18901 tgactggatc aaccacagcg gccaattcta agacatctga tcttttttga taataagcag
    18961 catgtacttt ttctgctact tgtccagcgc ctatgattgc tactttcttc atttatttct
    19021 ctctcctttg cttatttact tattgttatt ctttctctat tctttctcta aatcatttaa
    19081 atgacgcgct gtttccagac agtttttcaa gtattgcaat gattcctgat aaattttcac
    19141 ttcattttct cctcgcaaac gacattcata taccatataa ccttcatact cattttgaag
    19201 tagcgtttga aaatggcgag taaaatcaat tgcgccagat cctggttggt agcgatgatt
    19261 atctgctaaa tggatatgac ccacatactc tttttgcgta gtcaatgctt ttgaaatatc
    19321 atcttcttca atattcatat gataaaaatc agcgatgatc tgcacatgtt tcaattgatt
    19381 agagtcaatg taatgacgcg catccgctaa caaattgatc atatggtctt ggtatcggtt
    19441 caaaggctcc aaataaataa ccgtacctgt ttcttcggct actttatcta aataacgaag
    19501 tgattcgctg actgctttat agtctccttc tttgcttcgg ggtgaaacca tcggcggtaa
    19561 tcgataagtg aacattcccc aagctgctgg gataacgatt cctttgcctc caacctcgct
    19621 tagtgcacgc aaaatctcag caatttgacg tacaccatta agacgccgtt cttcgataaa
    19681 gtcaccgatc cacccatcgt agccgttaca agctgtcact actgggatcc ctgtttcttt
    19741 gattgcctgt ttgactgtgt cgatattttc tattaacaac ttaccgtcga tttcgtattc
    19801 ttcaaatcca cagtctttga taaatctaaa tttttctaaa atgtctcttg ggaaaaatgc
    19861 ttgatcttgc gtaccgaatt tcattgttct cctcctcgga cttgaacgcc cattttgata
    19921 ctttcttctg ggtgctggtc tacataacgc atgtaagctt ctgcgctttc tgcaaatggc
    19981 acaactggat caatgatttc ttcacaatcc aagtaaccgt tcatcaataa ttcccaacat
    20041 gtgtcctcga ttcgtttacg gttccatctt gggtaatctg ggtttggttc actagatgct
    20101 cgagcaaaga cgatttttgc attattgaaa tgtgcttcgc gaccaagatt aaacccagct
    20161 ggaaaaggtt tagcaaaggc aacataagaa atgatcccgc catagccgat ccctcttaaa
    20221 gaagcttgta atgcggcagc actgccactc gtttcaataa ctgaatctac tccacgttta
    20281 tctgtcaatt cctttagacg aaaaccgaca tctgctttca taggatctag cgtgtaatcg
    20341 gcaccgtatt tttctgctaa ttctctacgc tgcgctatgg gatcgatccc aacgatggta
    20401 gtagcacctg cttttttagc taattgaatc gcaatttgcc cgatagcgcc taaaccgaag
    20461 attgctacag catcacctgc tcgaacatgt gcttcccgga taccacctaa agcgaattga
    20521 gcaggatcgt aacatactgc atttttccat tgatccaacc gatcaagttt acgtagttta
    20581 taattatcaa caccgtttgt aatcagcgtt tcacgaatgg gtccataagt gcagactaac
    20641 tctccttttt gatactctgt caccaaactg cccgtttctt cgatcgtacc gacaatcata
    20701 tttcctaatt gaaattcgcc aaataccaca ccgcgttggc ttccttcttc tcttggcaag
    20761 aataggcgcc attcttctga aaattcttca tcgataaatg gacttaatcc tctaaagtcg
    20821 acaatttctg ttcctggttt tggagtagcg aaaattactc ggatacgtac ttcgttcttt
    20881 tcgatctcac ggtcttcgta atctttgaat ccggctattc ttggttctaa tgcaactaat
    20941 tttttcatct tttctttcct ctttcttttc tttttatcct tttacgccgc cttcgactaa
    21001 atcaccttta ataaatcgtt cagataacgc atacataatg atgactggta aagcggtcac
    21061 caatgaagcg gccatcattc gtccccaaat gtagtctggt gtactgaata atgtgttcaa
    21121 accgattggt aaagtaaatt tttcggaggt cgacaggaaa atcgaagcaa ataaataatc
    21181 attccacgaa accataaagc aataaacgaa gacagaaatg attccagaaa tagccaatgg
    21241 tataatgatc cgaataatga tctggatccg gctaagacca tcgatcattg ctgcttcttc
    21301 aatatcagtc ggaatcgtgt caaaataact ttttagcatg aatatcgcag taggaagtgt
    21361 ttgaacgacc atcgtgataa tcagtgctgt attggtatca tacaaaccta gaccggaaat
    21421 gattttaaat aatggaacaa cgatcaaaat accggaaaac atataaacgg tgtaaaagct
    21481 agcattgatt ttcgagcgag ctttgaagcg tagttttgac aaagcgtatg ccccgctgat
    21541 cccaatcact actgcagtta cggaggctat caaggagatc actaaactat ttttgaaata
    21601 catgatgaat ggaaaaatct cagcattgaa aatatcctga taatgttcaa aagtccattc
    21661 tttcggaaaa atagtttgtg tcgttgcaat tgcttcttgt gaatccttga atgatgtcat
    21721 cagcatgatc aaaaatggaa acaaattgac agctaatagc aacaaaatcg tcgcgtaaaa
    21781 taagattttc ctgctctttt tatttttcat ttcaagtcca ccttctttcg tgagagcaag
    21841 acgaccgctg caataatgat gaacaataga atcgatatag ctgctgcttt tccaagatca
    21901 ttgaacgcaa aggctgtctg atacaaataa acgcctaaga tattgacttt attcgtcagt
    21961 agatagacat ctgtaaacat atagaacatc cagatagatc gtaaaacaat cacagttgct
    22021 agtactggtt tgattgccgg cagtgtcacg atcttgaact tctgccaagc atttgcaccg
    22081 tccatttcag ctgcttcata aagcgttttg tcgactgttt gcaaaatagc caaaaatgaa
    22141 ataaacgcat acggatagta tctccagata gcaaacaaaa cgaccataaa gaagctagca
    22201 actggctggt cgaaccacag cggtgcttcg ttgaaaagct gcaacctatc tactaacaga
    22261 tcattgacga ttccataact attattgaac atatatttcc aagcaaaaat caaagaaata
    22321 gatggcgtaa cataacttaa taaaatcagt gaacgcaccg ttttcctaaa tctgaacttg
    22381 cggttaagca aaatagctac ggctaatcct aaagctgtac tgcctgctac aactaagaat
    22441 gtgtaagcaa ctgttaaacc taaagaacga taaaattcac tatcacttaa aatttcaaga
    22501 taattgctta atccgataaa aacggcgtct gagttaggat tcagcggcat atcgaaaaaa
    22561 ctgatctgaa tattggaaag cattggaatc agcactaaaa cagctaataa aagcatgctt
    22621 ggtgctaaaa gtcccatggc taattttaag tcagaatgtt tccttggacg attcattgaa
    22681 acctccccct gataatctgc caatagctat ctactttttt cgaacaccat tggcagaact
    22741 tcttgttatt tcgtattttt ttgtgcgtca gctaaagctt gatcgacatc ttcgtttccg
    22801 acagttactt ggttcactgc ttttccgatc acacctgagc ttgtgatatc tcccattttc
    22861 gtgaaattct tttccccgac tagtccaaag acttgtactt catcaaaagc actagcaatc
    22921 tcagatggca gctcgccaaa agacttgatg acttcatttt ctttgtaacc atccagttcg
    22981 actacttgtt tattcactgg ttgagcacca ccaggagaca tcaagaccca cttttccatg
    23041 tttttcggtt gagataagaa agctgtgaat gcttcagcag cctctttttg tttctcgtct
    23101 agaccagaag aaatcgtcaa tccagatact gtgccataga cagcttgatc tttttgtgtt
    23161 gggatagcaa aaccgatatt ttctgagttc cccgcttcat aaacagaagg caaaatgtaa
    23221 gttgaataga ttgccattgg tgctgttcca ttcatgaaag catctttgat ttctgtcaca
    23281 tcattagagc ctggcatcgt gtattgggat aagttttgat aaaacgacaa tgcttctctc
    23341 atcttttccg tatcgatcgt tacctcgcct tcatcatcca aaacatttgc tccatttgac
    23401 aaagcaaatt gagagaacgc ttgctcactc attgttcctt cagcagtagg catagcaatt
    23461 ccatattgtt tattctcttt atctgtgaaa tgttgagcaa tttttaaaat atcatcccaa
    23521 ttttctggtt ctgaaaaacc agcttctgat aatttttctt tgtcatacca aataccttga
    23581 acccagccgc taattggtgc agcaatatag ctttttccat cttctgaacg aacaaggttt
    23641 ttggctccgt cataataatt atcttctcca gcttcctcga taacgttttg gactgccgtc
    23701 tgatcaatca gttcatcttt atccatcact ttagcaaaat cctgactgac ttccattact
    23761 tctggtaatt taccggaacg agctaacgta acgatttttg tattgaacgc tgattcttct
    23821 accggcactt gcttgatttt gatgtctgga ttttcttttt caaaatcagc aaccagttca
    23881 ttgatcacac ttaatcgttc ctgttcgaca gaagagtgca tgaattgaat cgttgtctgt
    23941 tgtgattcgt tagagctttg actttcacca caagcagtaa gaagaaatcc agtagctagc
    24001 agacaggtag taacaataat ttttttcatt tttttccacc tcttatttta ttattttcag
    24061 ccacatatat tcatacggct ggaatatcaa ctttcgttct tgactgcaat ggataatttg
    24121 tccagaaaac aggtctaggt aatctccttt tggtaaaaga taacctgctg attgattgga
    24181 aaaattatgg ataactaaga ctttctcttc cttcgcttcg cgaataaaac tgataaaaga
    24241 atctgctgag tccagtaagt aaatcaaact attcggatgg aaggcttttt ctttttttcg
    24301 aatagatagc atctgggtca attcaccata tactgctgtt cttaatggat ctgtctgcaa
    24361 ctctttctca atatctgcta acaaaaattt ttgccgattg atttttcgat tctctcctgt
    24421 tttttctacg cctttgtaat catttcgact tcccagcaca ctttgaatat aaattgccgg
    24481 cacgcctggt aacgttacca aaaatgaatg agcagctaaa aagcgtttgc ttctccattc
    24541 cgtcgtatct gttggagaac ttaacgcatc tagatacgta gcgtttatct catatggact
    24601 ggtcgttcca tctgggtttt tcttgtagtt tactcgggca ccctctttct tcagctgttc
    24661 cactaattca aggatcgttt tttccggcag aatacctcgt accggattca atccgatacc
    24721 gtcatgggag gctaaaaaat taaaaaaagt tgtttttttc gatgcgaaat cgatggtttt
    24781 taaccattct ttcaacttac ttgtattacc cgaacgaatc gcttgaaggg tcaaaggtgg
    24841 tagcgaaaac tgatagacca tctgtgcttc attctcgcca ttcccaaaat aactgatatt
    24901 atctttgtgt ggcacatttg tctcagtgat caataccgtt cctggagctg cttcatcagc
    24961 gattgcacgg aataattgga tgattttatg cgtttctggc aggtgtatac aagaagttcc
    25021 tagttctttc cataaaaatc ccacagcgtc caagcgaata aatgaagcgc ctttttctaa
    25081 gtaaaacaaa agaatatcga tcattttcaa taaaacttct ggatttttaa aattcaagtc
    25141 tacttgatct tcgctaaaag tcgtccatac gtgtttttct ttcccgtttt tgtcaatgaa
    25201 cgttgtaagt aacgggctgg tccttggtct agtcacgctg cttgtatctg tatccagtgg
    25261 caaatcaata aaaaaatctt tgtacgtatc attcaagttt aaatattcct gaaaccaagt
    25321 actttcggca gacatatgat tgcagacaaa gtcgaacatt aaccgtgttt cgcttctcat
    25381 ttcttctata tcttcccatg tgcccaaacg gtcgttgatt gcctgataat ttacaacgga
    25441 gaaaccatca tcagatgtat atgggaaaaa tggcaagaaa tgtacaactc taaatgtatc
    25501 tgccaaatac ttttgataaa atttcttaaa tgtacgcaaa gttggttgct gctcttcaaa
    25561 aaattgatcc ccataagtaa tcaagaaaat atcttcttcg tcccaatgca gtttgcctgc
    25621 ctggcctttc ttctgctgat aaacactgac tttttgttca atcatagagg cggttttctc
    25681 agacaaatct gagtcgcgat aaatcgcttg taaaagtttt gtatacatcg gattcccctt
    25741 tcttttttgg gagcgttccc aacgatttga tcatattatg gaaaacgctt actgtcaata
    25801 gcattttttt aaataatttt gatatacaca aaaatacaaa taagaaagct tatgtatcaa
    25861 taattaatag cttcttaaaa aaatatggtc tctcatgatc atgcaagcta ttcctaaatt
    25921 ttcaaaatca tagacaaaaa agaatgtcta ttgtactatg gaattattct aaaacgctcc
    25981 caaaaaggag gtgcatataa aattgaaacc tactatttat gacattgcga aaaaagctaa
    26041 tgtctcaaaa tcaactgtct ccagagtatt aaataaccag ccaaatatct ctgataaagc
    26101 aaaagcaagt gtacttcaag caatcaaaga attgaattat gaaccgagca aaattgcaag
    26161 aggactgtca ggaaatggtt ttgacgcgat tctagcatta tctcatcgta cttctcatac
    26221 gacctatggc aatccttttt tttcagatgt tattcaatcc atttctgccg tttctgaaca
    26281 aaataacttc gacttgattc tacaaacggc aaaaacacca gaagaagagc tagaaaaatg
    26341 cgcgaaaaag atccaagaaa aaatgatccg aggaattatt attttaagct ctacgatgga
    26401 tgaaacactt ctttttgaat tggatcaata caatattcct attgtggtaa tcggaaaagt
    26461 cggaaacgac tacacgaaca tctactcagt ggacacggat aatttccagg atagttacga
    26521 tttggtggaa acactgatca agaatggaca ccgtcatatc ggctgtctcc atgctccgac
    26581 agaagtttat gtatccaatg atcgtctcaa tggttaccgt caatgcttat ttgatcacca
    26641 cctagatatc cgtaatgaat ggattataga cggcggcttt cgcttagaag atagcatggc
    26701 agcaatgaat gatttaatga agctacgaga aagaccaact gcgatttttt ctaccgatgc
    26761 attaaaatca ttgagtattt acaaagtggc agaacaatct ggaaagcaga tacctgatga
    26821 tctttcgatc gcaggattca gtgatccctt attgtcctcc ctattttcgc cacagttgac
    26881 tcggatagac attccgacaa atcagttagg aatcaaagcc acagaacttt tattccaact
    26941 aatccaccac caataccctg aagaaaaaag aatcattctt tcaaccgaga ttactctcac
    27001 agattcgatc caacaacaag aaatgtagaa cagaattata aaagaacaga aacactgagg
    27061 ataagtcagt tactctgttc ttttttcaat cactcatccc tcgttacccc ctcccggtat
    27121 tttagcgaat ttttcttatt ttccatctgt tttagatagc tgtggataac tataatgttt
    27181 gtgttaaact attttttcca cagggaagaa aaaactattt ttaaccacgt tgtgtataag
    27241 tttttatagt tcgttttttt aaacacattt acccttattt caatccatgt tatttgggga
    27301 tacttatctc taaaacataa atagaataac agacatgtct actggttttg ttttattcga
    27361 ggaattattc aataatagct agcaaaatat taaaaataac cgctctatct tcccatcaat
    27421 ttattttgca ttcaaaaaat gatctatctt tacttttgtt gattgacttc tcttggaaga
    27481 tgatcgttcc gataccttaa ttggatacga accgatgttg ttaagatcct ttcccacttt
    27541 tcttctagtt agacaaatta ttttagacaa accaaaaaag aggttgtgac aataatttgt
    27601 cacaacctct tttt
//
LOCUS       DAMEEU010000034        27602 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.035, whole genome shotgun sequence.
ACCESSION   DAMEEU010000034 DAMEEU010000000
VERSION     DAMEEU010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27602
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.035"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            214..1953
                     /gene="yfcC"
                     /locus_tag="PB779_001458"
     CDS             214..1953
                     /gene="yfcC"
                     /locus_tag="PB779_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDE0738987.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            2110..3294
                     /gene="iadA"
                     /locus_tag="PB779_001459"
     CDS             2110..3294
                     /gene="iadA"
                     /locus_tag="PB779_001459"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HDE0738988.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            3405..3608
                     /locus_tag="PB779_001460"
     CDS             3405..3608
                     /locus_tag="PB779_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDE0738989.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(3709..4371)
                     /locus_tag="PB779_001461"
     CDS             complement(3709..4371)
                     /locus_tag="PB779_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0738990.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4384..5886)
                     /locus_tag="PB779_001462"
     CDS             complement(4384..5886)
                     /locus_tag="PB779_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0738991.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNVKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDTTYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            6434..8113
                     /locus_tag="PB779_001463"
     CDS             6434..8113
                     /locus_tag="PB779_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HDE0738992.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            8240..8719
                     /locus_tag="PB779_001464"
     CDS             8240..8719
                     /locus_tag="PB779_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HDE0738993.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
     gene            8938..9618
                     /locus_tag="PB779_001465"
     CDS             8938..9618
                     /locus_tag="PB779_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HDE0738994.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            9626..10957
                     /locus_tag="PB779_001466"
     CDS             9626..10957
                     /locus_tag="PB779_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDE0738995.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            10972..11934
                     /locus_tag="PB779_001467"
     CDS             10972..11934
                     /locus_tag="PB779_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HDE0738996.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLASGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            12045..12383
                     /locus_tag="PB779_001468"
     CDS             12045..12383
                     /locus_tag="PB779_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HDE0738997.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            12462..13169
                     /locus_tag="PB779_001469"
     CDS             12462..13169
                     /locus_tag="PB779_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HDE0738998.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(13272..14753)
                     /locus_tag="PB779_001470"
     CDS             complement(13272..14753)
                     /locus_tag="PB779_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0738999.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLIKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            15062..15598
                     /locus_tag="PB779_001471"
     CDS             15062..15598
                     /locus_tag="PB779_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0739000.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            15676..17046
                     /locus_tag="PB779_001472"
     CDS             15676..17046
                     /locus_tag="PB779_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HDE0739001.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            17113..17448
                     /locus_tag="PB779_001473"
     CDS             17113..17448
                     /locus_tag="PB779_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739002.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(17529..18386)
                     /locus_tag="PB779_001474"
     CDS             complement(17529..18386)
                     /locus_tag="PB779_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739003.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            18493..19008
                     /gene="tadA"
                     /locus_tag="PB779_001475"
     CDS             18493..19008
                     /gene="tadA"
                     /locus_tag="PB779_001475"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HDE0739004.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            19031..19115
                     /gene="ffs"
                     /locus_tag="PB779_001476"
     ncRNA           19031..19115
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="PB779_001476"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            19325..20710
                     /locus_tag="PB779_001477"
     CDS             19325..20710
                     /locus_tag="PB779_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDE0739005.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            20747..21424
                     /locus_tag="PB779_001478"
     CDS             20747..21424
                     /locus_tag="PB779_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HDE0739006.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            21432..22196
                     /locus_tag="PB779_001479"
     CDS             21432..22196
                     /locus_tag="PB779_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HDE0739007.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            22198..22857
                     /locus_tag="PB779_001480"
     CDS             22198..22857
                     /locus_tag="PB779_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HDE0739008.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(22887..23396)
                     /locus_tag="PB779_001481"
     CDS             complement(22887..23396)
                     /locus_tag="PB779_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HDE0739009.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(23508..24506)
                     /locus_tag="PB779_001482"
     CDS             complement(23508..24506)
                     /locus_tag="PB779_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDE0739010.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            24707..25291
                     /locus_tag="PB779_001483"
     CDS             24707..25291
                     /locus_tag="PB779_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDE0739011.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(25368..26561)
                     /locus_tag="PB779_001484"
     CDS             complement(25368..26561)
                     /locus_tag="PB779_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDE0739012.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            26625..27005
                     /locus_tag="PB779_001485"
     CDS             26625..27005
                     /locus_tag="PB779_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HDE0739013.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            27079..27441
                     /locus_tag="PB779_001486"
     CDS             27079..27441
                     /locus_tag="PB779_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739014.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         8971 a         4664 c         5761 g         8206 t
ORIGIN      
        1 aaaaagaatt ttaaggaaaa acagagaaat aaaatactta atataaatgg aaagagaaaa
       61 aaataatcat acataggaga aaaaaaacaa aatagaaaaa agtgattttc taataaatta
      121 ttcatgtgga aatgtcattt ttactgtata attcatttga ttatccattt tttattcatc
      181 aaaattactg aaaaaagaaa ggaagaaata aatttgaaga aaacaaattc ttcaggaaaa
      241 ccgaaacgcg acttcactaa attatcgaca ccccatacgt atgtcattat ttttggtgta
      301 gtcatctttg catggatact gacttttgtc gttccagcag gaaagttcag cacgcaagat
      361 attgaataca aagatgcaaa tggcgaaaca agtactcgta ctgttttacg tcaagattcc
      421 ttccgttatg cttacgagct ggataagtcg tatgtgtttg atcaattaga agaactgcaa
      481 gatcatccag cagaacgtga aaaactggat gttccggaaa aaggattgga aaaagtcatt
      541 gctgacggag aaaaaaatct tacgcaggaa aaactagatg aaatctcctt gacagatgat
      601 gtgctttacg atcagtacgg cgaaaatatc tatgatactt ctaaaaaatt gcataaaaca
      661 gccaaaatat ggggaacaga tgattttggc ggctttggtt tcttaaattt tgtttttgaa
      721 ggactagtat ctggagataa gtatggatct gctgtaggga tcgctgcatt gatccttgtt
      781 gttggaggtg cttttggtat tattatgcgt accggagcga tcgacgcagg tatctatgcg
      841 tttatcagta aaactaaggg actggagcgt ttagctttac cgctattatt ctttgctttt
      901 tcattcggtg gcgctacatt cgggatggca gaagaggtaa ttccattctc aatggtgatg
      961 gttccatttg tcattgcgtt aggatatgac tcgatcgtag cagtaaccgt gacttatgtc
     1021 gcatctcaag tcggaaatgc gacctcttgg atgagcccgt ttagcgtagc ggtggctcaa
     1081 gggattgctg gaatccccgt gttgtctggt gcgacattcc gattgattat gtgggtagtt
     1141 gttactgcat tagccgctgg ttatatgatg atatatgcag aaaaaatccg taaaaaacca
     1201 gaaagttcgt tgacttacaa atcagatgat tatttccgtt ctcatatcaa aaagacatct
     1261 gatgaaaata aaaaattcat gcttgggcat aaattgatct tattagagat gttagttgtc
     1321 cttgtctgga tcgtttgggg cgtgactcaa aaaggctatt acattccaga aatcgcttct
     1381 caattctttg tgatgggatt agttgctgga atcattgctg ttcttttcaa attagatgga
     1441 atgaaagtca atgacatcgc ttcttctttc caatctggtg cagctgattt agctggtaca
     1501 gcaatcgtag taggtatggc caaagggatt cttcttgtct tgggaggatc tgatgcatct
     1561 gttccttcag ctttgaatac gattttgcat gggatcggga cggcgttgac cggtgttcca
     1621 gctgtcattg gtgcttgggc gatgtacatc ttccaaagtt tgttcaactt ggttgttaca
     1681 tcaaattcag gacaagcagc tttgactatg ccaatcatgg ctccactggc agatttagta
     1741 ggtgtatcca gacaagtagc agttcttgct tatcagcttg gttcaggttt tatggacgct
     1801 tttacacccg tatcagccag cttgattggt gtgctaggtg ttgcacggat cgaatgggca
     1861 aaatgggcaa gattccaaat caagatgcaa ggattcctgt ttgttttagg aactattttc
     1921 atcatgattg ccattgcaat aggtctgcag tagtactgga gacctgtaaa taaaaaagta
     1981 atccaaacag tagataagga ctccaagaac cgtcatttta cggtaaaatc aaaggagtaa
     2041 agatcctatc gtttggatta ttttttaaga tcctatcatc agttatactt aaagaaagag
     2101 gaaaaatgta tgaaaatcat tcgacaaatt gaagtgtttg caccagatta cttaggaaaa
     2161 atggatgtac tgattgccgg tgggaagatt ttggctgtag aagaacagct agaaggcggc
     2221 tacgaaggag tggaagtaga agaactttca ggtgagggaa aagtactaac cccgggtttc
     2281 attgactgtc atttccatat tttaggtgga ggaggagaag gcggttatca aaatcgaacg
     2341 ccagaagtca cattgagcca attgactaca gctggtgtaa cgacagttgt cggttgtttg
     2401 ggaacagacg gagaaggtag agatatgact gcgttgatca gcaaagcgaa aggtctggaa
     2461 gcagaaggaa tctccactta tgtatacgaa ggttcgtacc gattgccggt aaaaacagta
     2521 acagattcta tcatcaaaga ctttttgaca attgataaaa ttatcggaat cggagaaatc
     2581 gcagtatccg atcaccgttc ttctcagcca agttttgaag agttcgctcg tgcagtagca
     2641 gatgctcgtg taggaggcat gttatccgga aaagctggga tcatcaatgt ccacttaggc
     2701 ggaggaaaaa gaaagctaga gctattgaca cgaatcgtag aagaaacaga aattccgatc
     2761 acacaatttt tgcctactca tgcaaatcgc acaccagaat tatttgaagc ttgcgtggca
     2821 tttgccaaac gtggtggcac gattgacttc actgctagcg aagatcctga tttttgggag
     2881 aagacagatg gtgaagttcg cttcagcaaa gcactgaaac gattgatcga ggaagatgtt
     2941 tctttagata atttcacgat gacctcagat ggacaaggaa gcttgcctta ttttgatgaa
     3001 aacaatcatt tcctagggtt aggagtagga agtgccaagg cattgctagt agggatcaaa
     3061 gaagctgtgc aaaaagaaag tatccctttg gaaatcgcct tacgagctat aaccagtaat
     3121 ccagcacgta tattgaaatt ggataaaaaa ggaaaaatcg aaattggtgc tgatgcagat
     3181 ctgtgtatct tggataaaga aacgcttgat attgatacag ttatcgctaa aggagaaata
     3241 atggtccaag aaaaagaagt caaagtatgg gggactttcg aaaaaagttt ttaatcaaca
     3301 gctctaacta tcttttttag aaaacgagcg ttctgtttgt ctgtatctgt tgttgatgtt
     3361 accctgaagg tagatcaata aacaaactaa gaggaggaag cacaatggca gatttaaaag
     3421 gacgttctaa agatatgaaa gataaagtag tcggtgaagg aaaagaagca tacggcaaag
     3481 caacagacga caagagcaaa gaaacagaag ggaaagcaca atcactaggt gctgacatca
     3541 aagaaaaagc tcgaaattta ggcgacgaag tcaaagacaa gttttctcga aaagacgaaa
     3601 aaaaataaaa accacttatt actaattgaa tcaagcaaat aaaaaatccg aaccatatct
     3661 gcgagacaga tatggttcgg attttttatt tgatcattat cctgtttttt aaacttcgat
     3721 tttttgaaat tttttatttt ttagttcaaa gacttcatca cagctttttg ctacttcaat
     3781 ctcatgagtc acgatgataa tacagcgatt ttgttcatgg gcgatttctt ggaaaagttt
     3841 gacgatatct tgtgaagttg tttcatctag atttccagta ggctcatccg ctacgattag
     3901 ttgatgttca cagcagatag cacgaacgat agcgactcgc tgctgctgac ctcccgaaag
     3961 tttggtcacc tgtttttttg ctaatatttc atcaattcct acacgagcca gtcgatctaa
     4021 agcaacttgt cgataattct cttgcttggt cttagtgatt tccattgctg ctatgacgtt
     4081 gtctagagcc gataaataag gaagcaagtt gtaagcttgg aaaataatcg agacatcatt
     4141 tttacgataa cttcttaacc cgattttgtt cagtgaacga tcttgatagt atacctttcc
     4201 ttcttttggt gcatctagtc cagaaataag cgaaagaaaa gtcgtttttc cagaaccact
     4261 tgctcctaaa atagcgtaca tttttccagc ttcgaaattc agttctacat ctttataaag
     4321 cgcatcttgc ggatcttgat accaaaatcc caattgttct gtccgtaaca tcaaattcct
     4381 cctttagttt aataggattt ttcttgggtt taatcttaat atccctatag aagctaaaaa
     4441 gacagaaaac agactgattc caaatgctac tccggctaat agtcccaatt gtgcaggttt
     4501 gacattgatt tccaattcgc tgacttgatc agaaacagca aatggattat tcgtggttcc
     4561 ttgttgacca tcgcgttgac cgccttgttc ttgtctgtta cctggcattt gtccaccgcc
     4621 aggagcttgc tggttttgtg tcgtggtttc tgtctgttgg tcaagtagct gctgtcccac
     4681 ggcattcgcg acgacgtttc cgctaagcga agcaactcct aatgcaagaa tcatacaaat
     4741 agccacttcg gtaaacaatt ggagaatgat tttacttctg gattctccta aagatagcaa
     4801 gacgcctaac tcatgccgac gctcccgaat ggtaatcata atgatcagag taagtatgat
     4861 aataccggct acagccacta gtaaaacaac atttttagaa aaacttgcca cgttgtttaa
     4921 aggttccaac attgactgat acatggaatc atttgattgt aagctaaatg tatctgtgtc
     4981 gatcagcttc tcagcttctt tgagaaactc atccatttta tctggatcag atagagtgta
     5041 aatagcagaa tctatcgtgt tatcgtcaga tgtcccattt agttcatttg caaaagtgta
     5101 agaagtgtaa agtgtattcg acggattcat gaagttgaat ttcataccca tactgccgct
     5161 tgtttcgctg gattcataaa ttcctttgat cgtcatttca taagtggtat cttcatcttc
     5221 agtactcgtg attgtgaaag tatctccgac tgccaggtca tttgtttctg ctagagtaga
     5281 atcaatgact acattgtttg tgcctttgtc gctgtcatct attccttcac catccgtgat
     5341 ttttgctgtt ccatcagaaa aattactatt ttgtgcagtt gctgacacac cactgatttg
     5401 aaagtctgct tgagtcattt gcggattccc gcccattcct ccagcaggtt caccgcctgc
     5461 atcagtagtt tctgaactgt cttcacttga atcagaacta gtgatggcag ttattccatc
     5521 ttttgccata gctgaggcgg aactttcaaa ggaataactc tttacattat ctaattcagc
     5581 tattttttcc gcgtccgtta aggaaactgg tgtaagagaa aaactgcctg gatctggacg
     5641 ttcttcagtg gtagaaccgc ttgaagaagt ttgttcctgt tttttaaatg aagcttctcg
     5701 attggcactt aaagtcactg ttgctccaac ttctttttgt gcttgattcg ctgcttcttc
     5761 tgcagcgctt cgaatcgtga ggccagctag cacaaaaata agaatggctg tgaacacggc
     5821 aaacaataac aatgaacgtc cccattttac ttttgtactt ttccatgcac gtttcataaa
     5881 attcatattt tgcatccctc ctagtagatg catttgataa tagacaacct atcttaaagc
     5941 tagcttaaat cttatgctgt ttgcacacca tcaacatgag gttctgtata tataaaaagt
     6001 cactatagtt attgcaaaaa atgtggtaaa atgaaaaaag tatgtttcaa accgacgaag
     6061 aagaaatgaa agaggaatag caaaagaaat cctagatgct acagagggat ttttacgtgc
     6121 atagttgttc taacaattgc tgatactagc gatttagttt atttgttgta taataatggg
     6181 gaacagctga atacttatat aagtattctg gctatagcgt ttcgcaaaag atccattttg
     6241 ttaatgaagt atatccaaaa taaaatgccc atccaactgt cagaacgcgg atgtgctggt
     6301 aattttcctg ctgattctcc ataagttgag aaatagtgat tttgcatatg cttcattgga
     6361 atggctcata tatttagata aagaagaaaa tcgacatctt taaacttgga tgtcataaga
     6421 agaggtgaag tttgtgagta ccattaaaat tatcccatta ggcggcgttc gtgaaaatgg
     6481 aaaaaacatg tatgtcgcag aagtgggcga ggatattttt attttagatt gtgggctaaa
     6541 atatcctgaa aatgagttgt tggggatcga cgtcgtaatc cctgatttta cgtatttaga
     6601 agaaaacatt gatcgtgtag ctggtgtctt tttaacacat ggacatgcag atgcgatcgg
     6661 ggcacttcct tacttgttgt caaaaatttc tgtaccagta ttcgggacag agttgacgat
     6721 cgagttagca aaattgaatg tcagtcgtaa tgaagcagcc aaaggattta aggatttcca
     6781 tgtggtagat gagcatacag aaatagactt tggtgaaaca gtagtgagct ttttccgtac
     6841 cactcatacg ataccagatt cagtggggat caatctgaaa acaaaagaag gtagtatcgt
     6901 ttatacggga gattttaaat ttgaccaaac ggctatccca atgtatcaaa cagattatgc
     6961 acgattggcg gaaatcggca aagaaggagt cttagcctta ctaagtgaat cggcaaatgc
     7021 agaaaatcct cagcctgtag cttctgaagc ccaaatagca gatgaagtat ttgatacgat
     7081 caaatattgg gaagggcgta tcatcgtcgc ttgtgtagca agtaatttgc aacgagtgca
     7141 acaagtattg gatgcagcag aaaaagcaca acgaaaagtt gtcttgactg gtcaagattt
     7201 cgaacgaatt attcgcacag cgatgcgttt agaaaaactt caattaccaa gtgaagatct
     7261 gcttgttacg ttgaaagaca tgaaaaacta tgatccagaa gaactgatca ttttagaaac
     7321 tggccgaatg ggtgaaccca tcaagtctct gcaaaaaatg gcaaacggta cacaccgtaa
     7381 tgtcaagatt gaagaaggag atttggttta tatcactact acgccaagca tcgcgatgga
     7441 aaccatcgtg gcgaaaacgg aagatatcat ttatcgagct ggtggaacag tgaagttgat
     7501 ctctgagaat atgcgcgttt ctggccatgc caatcctaat gacttgcaat taatgatcaa
     7561 tttgatgaaa ccaacatatt ttgtgccagt tcaaggagag tatcgtgaat tagctgctca
     7621 tgcagatttg gctcatgcag tagggatgcc atacaaaaat atctatatta ctggacgcgg
     7681 agacgtgctg gaatataaga acaagcgtat gagtgttgca ggaactacaa gtgcagaaaa
     7741 tgtaatgatt gatggattag gcataggtga tatcggaaac attgttttac gtgatcgaaa
     7801 aatcttgtca gaagacggga ttttcgtagc ggttgtcact atcagtcggc gagaaaagaa
     7861 aatcatttca aaacctcaaa ttacttcacg gggattcgtt tacgtaaaag ctagccgtga
     7921 tctgatgaaa gaaagcagca atatgattga aacaatcgtt gagaaacatt tagaaagcaa
     7981 tgattttgag tggagcaaat taaagcaaga catccgagat caattaggcc gttacttatt
     8041 tgaacaaaca aaacgccgcc cagtgatctt gccagtcatt atggaagcta ctcaacgtcg
     8101 aaataaaaaa taaacaaaaa gagtaagatg aacctctcta tagagtgctc gtcttgctct
     8161 ttttttgcga aaaacaaata atttttgaat acagcatccc tcgctttata ataaacgata
     8221 gaataaaggg agtgaatcaa tgatgagtca aacaaaagtc gaacgttatt tagaagaaca
     8281 aaagatcagc tatcaaccac ttgattttag tcatgtggta gaagaatctt tcacagaaga
     8341 actacaaaaa agagggattg atccagcttt gatatgtaaa actctcgtag tgaaaggaaa
     8401 caaaactggg gtgatcatcg cattgattcc tttgaacgat cacttagatt acaaaaaaac
     8461 gagacaagtg acgaaagatc gtaaagttgg ttttcctgga atggattttg tattaatgca
     8521 tacaggatat ccccacggag caaacacccc tattggaata aaactcgcac atcctgatta
     8581 ttgtttttta gcagacagtt ctttaaaaga aaaagaagaa gtaattgtgt caagcggtga
     8641 aatcgggaga agccttcgga taaaagtagc cgatttagaa aagatcgtcc atcctattta
     8701 cgctgattta attagttaag ggacgagaag agaagctaag cagagcagag acctcaaact
     8761 tgagattata tctgcttggt acttggtgca tcctgtatta tctgttacaa ttgctttgta
     8821 catactgtac tatcaatcca atgaaaatat atttagcagc tatatttttt cattgatgtg
     8881 caagtgatga aatcgttttt aataaaaaag atacagagaa aacgcgaggt gtaaaatatg
     8941 aaaattacgt atcatggaca ttcctgttta acaattgaaa tggaaaatgg ccaacgcgtg
     9001 atgattgacc cgtttattac aggaaatcca ttgacagact taactgcaga agaagtaaag
     9061 acagattggt tgctgattac tcatggtcat agtgaccaca taggagatat gattcctatt
     9121 gcaaaagaaa atcaagccac aattatcagt attgttgaga ttgctgatta tgcgaacagc
     9181 agaggagtag attcattcgg tatgaatatc ggtggaaaac atgcgtttcc attcggcgtg
     9241 gtaaaattcg tacatgcaca gcatagttca agctatgaag tagacggtat cgttcagtat
     9301 atgggcgagc ctagcggaat tattattcaa gcagaaggaa aaacgattta tcatgcaggg
     9361 gatactgctt atttcagtga tctaggattg cttgcagaag aattcgatat tgatgtcgct
     9421 ttcttgccga ttggcgataa ctatacgatg gggccagaag atgcagcaaa ggctgcgcaa
     9481 acaattcgtg ccaagaaagt agttccaatc cattacaata ctttccctgt cattgaacaa
     9541 gatcccgaat cttttgtaga gttactggaa gatagtgaag gaaaaataat gagcgtctcg
     9601 gaaacgctgg aagtgtaggc agaaaatggc gacaaaacat gatttgattt tagaatatat
     9661 tgaaagttta cctgttggca atcgaatttc tgtaagaagc atcgcaaaag aattgaatgt
     9721 cagtgaagga acagcgtacc gtgcaatcaa agatgcagaa aatgtcggac tagtttcaac
     9781 aattcaacga gtagggacca tccgtatcga acgcaaatta aaaaaacata ttgaacgttt
     9841 gacatttggc gaggtcgtca ggatcattga aggggacgtt ttaggcgggg cggcaggatt
     9901 agacaaggtc ttgaataaat tcgtcatcgg cgcgatgact aaacatgcca tggaacgcta
     9961 tattacgcca ggatcactaa tgatcgtcgg caaccgggcg gaagtccaaa aattagcatt
    10021 ggaagatggc gccgcagtat tgatcacagg aggattcaat acgactgctg agattgcaaa
    10081 gctagctgat gatcttgaaa tgccgatctt acgcacctct tatgatacat ttacagtcgc
    10141 aaccatgatc aaccgagcgt taagcgacca attgatcaaa aaagatatca tgcttgtcag
    10201 tgatatctat atgccagctg aaaagactca ttatttgcag cagacagata cgatttctga
    10261 ttatcagcgt ttgtcagaag aaacgcagca ttcgcgtttt ccagtcgtca accgccatca
    10321 tcgtttgatg gggattgtta cggcaaaaga tgttttaggg aaatcgccaa accagatcat
    10381 cgatcgggtg atgacgaaag aaccaatcag tgtaaagaaa acaatgagta ttgcctctgt
    10441 tagccatcaa atgatctggg atgggctaga agtcatgccg gtcgtttccg atgacttgac
    10501 attggaaggc ttgattaccc ggcaagatgt aatgaaagcg atgcagcttg tccagcgaca
    10561 accgcagatt gcagatacga tttcggatca gatatctgga aatatccata cgattgatac
    10621 tgaccgtgaa ggaaatcgtt tggaaaaccc taagttcaaa ttcgtagtag caccacaaat
    10681 ggtcaatggc gttggaacca tttcttttgg cgtacttagc gaaatcattt ctgatgtcgc
    10741 acaaaaaaca atggtgatga accaaaaacg aaatatcttg attgaacaag tgaacctaca
    10801 ttatttgcgg ctgatccaat tggaaagcga attagacatt cgtccacgtg tattggaaat
    10861 cggcagacgt tccgctaaac tggatatcga agtgtttatt gaaaacacca tcgtttccaa
    10921 agcaatcgtt gtttgtcaag taatggaacg ttcttagaaa gcaggagtga aatgacagta
    10981 cagcaagaaa tagtagatac aataaaaaaa tacgataaaa tcattatcca caggcatttg
    11041 cgccctgatc ctgatgcatt aggatcacaa gtaggattag ccgaactatt acgggaaagt
    11101 ttcccagaaa aagaaatacg tcaagtaggt gaaacgattg aagggcttcg ctttttagca
    11161 gaaatgcaag aagttgaaga tgtcttctac caaggagcgc tagtcatcgt gactgataca
    11221 gctaattcac ccagaatcag tgatcaaaga tatcagttgg cagaaaaact gatcaaaatc
    11281 gaccatcatc ccaatgatga cccttatgga gatcttgtgt gggtaaatac aaaagcaagt
    11341 agctgtagtg agatgattgc agaatttgct ttgatgtttc ctgaatcttt aaagatgaac
    11401 gttaaggctg cacggttact ttatgcagga atcgtcggag atacagggcg ctttttgtat
    11461 ccctccacga cgtcccgtac attagagatt gcttcgatat tgagaaatta tccatttgat
    11521 gcaagtgctt tgaacagaga gattgaacaa atgccgatga aagtcgctaa actttccggt
    11581 tatctttatc aaaatatcca ggtggatgaa aatggtgcag gaagaataat ccttccgcaa
    11641 gaaattcttg ataaatatgg aatcgatgat tcagagacag cttcgatcgt ttcacttcct
    11701 ggagtgattg acgaagtgct ggcttggggg atttttgttc agcagccttc agggtattac
    11761 cgcgtacgtt tacgttctaa ggggccgatc atcaatgaat tggctaaacg ccatcatgga
    11821 ggaggccatc cattagcaag tggtgcgaat gcaaaagatt tagcagaagt agaggaaatc
    11881 tataaagaga tccaagatat atgccaatcg tataagagca gaaaaacaga atgatacttc
    11941 gttcgaaaac gtgccttttg tagtaaaaat cacaaatgta tcttttcaag atcttctttt
    12001 tccgttacaa tagtgctcac taaagatttt aaaggagaaa gaagatgaca ttaccaaatt
    12061 gcccagaatg tggctcagag tacacatatg aagatcgagg cttgttgatt tgcccagaat
    12121 gcgggaacga atggaacaaa gaagaacaag aaactgtcat agaagacgga ttagtggtat
    12181 tagatgcaaa tggaaaccgt ctgttagagg gcgatagcgt gacagtgatt aaagacttga
    12241 aagtaaaagg tgcgtcaggt gccattaaac aaggaacaaa agtcaagaac atccgtttag
    12301 tagaaggcga tcataatatc gattgcaagg tagaaggatt tggaccgatg aaactgaaat
    12361 cggaatttgt gaaaaagaat taaagaatat tcaaggtctt ttcacattct tttcctacta
    12421 ctaatgataa aataaagtaa acgaaaagga gtgaaacgaa aatgtatggt tatggaatgt
    12481 atggtttttt agatccgaca tttcttttgg tcattcttgg attagttatt tccggaattg
    12541 cgtcagcgta cgtcaatagt actttccgaa aatacgatca agtgagaagc aaaaacaatg
    12601 tgactggtac acaagcagca caatatatat tacaaagtca acagataaat aatgtcggtg
    12661 ttcaacaaat tgccggagat ctcacagata actacaattc aggtaataag atgttgagtt
    12721 tgtctcaagc aactgcacag tctacttcag ttgctgcgat aggtgtagca gctcatgaat
    12781 gcggacatgc ggtacaagat gcttcgggtt atgtcccatt gaagattcgt gcagcacttg
    12841 ttccagcagc taactttggt tcgatgattt cgttcccctt gattatggta ggtgtattgc
    12901 ttagctggaa ctctacgtta atcaatatcg ggattttcgc tttttcttta gcattacttt
    12961 tccaattggt gacattacca gtcgaattta acgcgtctcg gcgagcaatc caaattttga
    13021 gtgaaggcgg actactgacg gaagaagaag taccgatggc aagacacgta ttatttgcag
    13081 cagcactgac ttatgttgca gcagcgcttt cgacattcct gcagctgttg cgcttgatct
    13141 tattgttcgg cggcaaccga agagattaaa ataaagaagt tgtgaaatca gcgctttgat
    13201 ctgagctaat accgagagtt agctgattga ataccattta tttggaataa gaggatgtga
    13261 caagaatttt gtcacatcct ctttgttttg ttctcataac cttttttcat atacagttca
    13321 tgaaccgctt ttattaactt gccaaataac actgtattgt gcgttgtatc cagatagaaa
    13381 gtctccgttt catctgaaat tttctcatgc tgatctgtaa tgatcaaatc agcatgttct
    13441 gaatatgcgg taattttaac agcatctttg cgaaataact gctgcaaatg gctttgaaga
    13501 tgataatttc ctgtaaactg tttggttatc tgcaaatgga tgagtaactg ctctttcgtt
    13561 tctgtttgta gtaagtgttg gatcaattga ctaaggtatt gactgatttg gtttctttcc
    13621 ccattttttg aaaaaattgt atcgattttt tctcttaatt tcttttcctg tataaaagaa
    13681 ctagaatgat tggacgtggc ttctggaaag caaagtgtag aaaaactact gctggattca
    13741 cccaacagtt cgaaaaaaac aactgccaac acaagaaaat aaaaataaat tggtatttta
    13801 ttttctaaat ggttgagagg aaactgttga gttaagtaag tcatcaattg accgacttgt
    13861 cgacaaataa ggtttttgct tgtggaaaat aaaaaaccaa tctcctgttt ttgtcgaaaa
    13921 gagatttgat ttggaaaaaa acaatagaaa aaataattaa agtaggctct ctctgtttct
    13981 gtctcttcac aagggcgact cactgaaaaa gaagtaaagt attctgaata atcatgtgta
    14041 tgctgcaata agtccatcaa ttcagtgatt tcagaagaag tttttggaaa atatgcctgt
    14101 tgtttgtttc gtaatatgaa taaagttaac agcaagtaga tatttttttc ttgttttgaa
    14161 attttttcta tttgctcatc tgtactgttc atttttagtg catttaattc aagtgaggaa
    14221 aatggccaat cgttacctcc aaatgtatct gaaagaaaaa agtaaagata gagacggata
    14281 gataactcat ttccttcaag agtacagcaa ttttttacag ataggatccg taaatggaat
    14341 tttattaagg aatgattgag ctgttttgtc agtttttcga gataggaggg cgatatataa
    14401 agttgttcaa gtaaatattt ttttggtaca gcagtttgtg gataattgat tagtaacatc
    14461 aaatagttaa aacgattgga ttcttttagg tagcataatt ttaacttaga aaaaacagct
    14521 aactttttag tttgatcggt ttctttggtt tggatctctc ctttatgatt agaataaata
    14581 aattcatcaa tcaataaaaa ttgcttgagt gatacattta tttttcggat cagttctttg
    14641 attgtccgtt ttggaatatg taagtcattg gataattctt gtaaagaaca attatttttt
    14701 tgaatgacca tttgtagaac aagtaactct ttttttcttg cttcaattag cataaatacc
    14761 tcctttttat tctgtttttg tatatagtta gacaaaaact gtgagtggaa agtcatttca
    14821 gtctgtgtta ttctcacaga gtgtcgcctt cttttttata taacgttatt taattttttt
    14881 gttaccttgt ttattctatt gtttatttcc tagggtattt tgtcaagata ttcttgtttt
    14941 taaggcggaa aaattgattt ttaatggata taactaaata tgttttgata attatcaata
    15001 atatttttag aattatttat gttatttatt tatgggtaga tgaaaagaga cggaggtaag
    15061 aatgatgggg agagtaacaa attatagtaa agaatatttg ctgttcaaaa gtatggtata
    15121 cgtggaagaa tatggaatga agtcaattac tgcaagagag ttagcagagt tctgcggttg
    15181 ttctacatac ccgatttata cacatttcaa atcaatcagc gggttaaaag agaagatatt
    15241 agaagaaatc actgtttatt ttgaaaacta cttagctgaa tgcagttccg atgatgtttt
    15301 aagcattgtc tacttattga aagatttttt ttctatccat gaaagtattc gtgaaatcat
    15361 tgcaaaatct gatttagaca tggattcgct atttaagcgg ccatttttct catatgtcaa
    15421 aggtcacacg aagatcaaag aagaaaagtc gcttgaattg gtatggctta atgcattggg
    15481 aagtttgcgc tcagatgatt cttctcaaga ttttcttgaa atgatgaacg ctgtttggga
    15541 taaaaacgag gtgacggatg aatacttgga aaatatctta aaggaacagt caccttaggc
    15601 agcaacatga aaaagtagat cagccacctt tatttttcgt aaaaaagatt gtaaaatgtc
    15661 taacgaaaca ttggaatgaa ggaggaagcg acaacgttac cacagcaatt tatcaaaaaa
    15721 tatcgtcttc ttttaggcga agaagcatcc gatttttttt ctgcgcttga acaaggaagc
    15781 gtgaaaaaag gatttcggtg gaatccacta aaaccggcag gattggacat ggtccaaact
    15841 taccatagcg aagaattaca acccgctccc tacagcaatg agggatttct tggcactgtc
    15901 aatggaaagt ctttcctcca tcaagctggg tatgaatata gccaagaacc aagtgcaatg
    15961 atcgttggaa cagctgctgc agcaaaaccc ggtgaaaaag ttttggattt gtgtgcggct
    16021 cccggtggta aatcaaccca attagctgct caaatgaagg ggaaagggtt attagtgacg
    16081 aatgagatct ttccgaaacg tgcgaagatt ttatcagaaa atatagaacg atggggagtt
    16141 tcgaacgcaa tagtgacaaa tcatgcaccc gcagaacttg tccctcattt ttcgggcttt
    16201 tttgatcgga tcgtggttga tgctccttgt tcaggagaag gaatgttccg aaaagatcca
    16261 aatgcaataa aagagtggac agaagaatct ccgctatact gtcaaaaacg tcagcaagag
    16321 attttgtctt cagcaataaa aatgctaaaa aataaaggac aactgattta ttcgacttgt
    16381 acgtttgcac cagaagaaaa tgaagagatc attagctggc ttgtagaaaa ttatccagta
    16441 acgattgagg agattccttt gactcaatcc gttagttcag gacgttctga atggggaagc
    16501 gtagctggtt tggaaaaaac aatacgtata tggcctcata aagatcaggg tgaaggacat
    16561 tttgttgcaa agctgacttt tcatggacaa aatcagatgc ataaagaaaa gaagacacga
    16621 aaaaaaagta aagtgcaaat gacaaaagag caggaaaaac tctggacgga gttttcaaat
    16681 gattttcatt atgaagctac tggaagactt ttagtgttca acgaccatct ttgggaagtt
    16741 cctgagttag ccccttctct cgatggttta aaagtcgtac gtacaggttt gcatttagga
    16801 gatttcaaaa agaatcgatt tgaacctagc tatgcattag cgcttgctac aaaaaagata
    16861 gagaatatac cttgcttgcc gatcactcaa aaggaatggc aatcttacac agcaggagaa
    16921 acatttcaac gtgatgggaa tcaaggatgg gttttgctag tattagataa gatacctgtc
    16981 ggatttggga aacaagtaaa aggaacagta aagaactttt tccctaaagg attgagattt
    17041 cactgagtgg attagttcgt ttattttttt gtctatgcta tgatggagat agataaaaag
    17101 gagctgatac ttatgaaaac atcaacaaaa gtaacaatcg gattaagcgt agcagccgct
    17161 gccagtgtag cgacagcagt cgttgtatcg ggaaaagtaa tggaaaagat ccatcatatg
    17221 actactcgga cgaaagtaaa aaaattcgtc tatgacaaat ttgatggaaa tgaaaaatta
    17281 ctagaaatcg tagatggtct ttcagatagt gacttggatt ctttgatggg aatgttagca
    17341 aaaatcaaat caggaaaaaa gaaaatctct gtttatggtg attcaatcaa agattcaacc
    17401 gaagatgtaa aagaccggct aatgcatttt gttgaaaaaa tgatgtaaga gaaactagct
    17461 tttgaacact attcattcga aataaggggt tgtgacaaaa ttattgtcac aaccccttta
    17521 atctatcttt aattatgttc atgaagcaat aaaagatagc aaaacagtaa atcgttggct
    17581 ttttttagat tgaaaccaga ctgttcttga aatttttcga ttcgatattt tagagtatta
    17641 cgatgaagaa acagtgtttt tgcagcagag ctgacattgc ctaattcatt ccataattct
    17701 tgaatgatca cttccatttc attttgtttg atcagttcta tgtaactttt gatcaactta
    17761 ctatctttta cagtatcttt tgtatagtaa tgtaaagcca catcttgcat agaaaaagta
    17821 cggctgtgag tataaagatt gttttgctct gttaaaaaaa tttttctttc ttcagcaaac
    17881 aaagggacga ggtcggtgcc aggtgaatgg aaagaaccaa cgaatacaga cgttgtcgta
    17941 tcaaaatcag catctaaaga tagaaaaata ccgttgattt cagtagcatc aagataatca
    18001 cggtttattt gttcgactaa gagcgcatct gtgtctgtat aaaaaaagaa atcagcagaa
    18061 tagcgaaata attccaaaat agtatcttgc cattcttttt ttaagaattc tccttttgat
    18121 tcgacgtgaa gctggatcaa acgaaagctt ttttcttgaa cacaagaagc atctttaaaa
    18181 agatagtgat accatgggtg ttttttttga tcgttgatta cagggaataa cgctttcaaa
    18241 aggctggttt cttgttgaga taatgaatct tgtttgatcc agataaaagc atcatcaatt
    18301 gcaaaagaaa ggatatccgc ttctgatgct ggagagtttt ttttctgtgc ttgtgggtaa
    18361 agagcaagta atttatccat tttcatcttg ttcacctctt gtatttattt taccatagaa
    18421 aaaaaagtta gttacagcct ttttatcata tgctaaagta aaacaagaaa aaacaaaggc
    18481 agggaagggt aattggtaaa tacaaatctt gatgcagtag aaaaagaaaa atggatgcgc
    18541 cttgcattgg cagaagcaaa gaaagcagaa atgcttcatg aagttccgat tggagcagtg
    18601 gttgtattgg atggaaaagt gattggaaga ggatataacc ttagagaaac cacgcaagat
    18661 gctactacac atgcagaaat gcttgcaatc aaggaagcct gtgaaaaagt gggaagctgg
    18721 cgcttggaag atgctgcact ttttgttacc ttagagcctt gtcctatgtg cagcggcgcg
    18781 atgattttgt ctcgtgtagc agaagtttat ttcggcgcgt atgatccaaa aggcggaaca
    18841 gccggtacct tgatgaatct tttggaggac gagcggttta accaccaagc atatgtagaa
    18901 ggtggcattt tagaagacga atgtgggatg attttgactg actttttccg aaagctccgc
    18961 cagcgaaaaa agaaattaaa aaaagactgg tcaacgaatg aaaaataagg tatactattc
    19021 tttgccgaaa ggctaggaca atggtgggct tgtgaagcgt gtcaggtctg gaaggaagca
    19081 gcactaagca ggttccgcca tgtgtctgat tataatgaaa cgacaacaga ctttcgggtc
    19141 tgtttttttt atttttatag tactgtaaaa atgaatgttc ctgatttttt agccagactg
    19201 atttatcgaa tattgtactt atacaatttg cttcaaggca ggaaaaactc tgaaatagag
    19261 cttgtttcaa tggaagaaaa agctgcctat ggtatgataa agataaagag aggcgagagg
    19321 gtacatggaa aaaatagtga ttttacatac gaatgatctg cattctcatt tagaaaattg
    19381 gccaaggatc agaaggtttt tggatcaacg taaacgagaa aacgaaaaga aagaaaaaac
    19441 gacaacgatt gcagtagatc taggtgattt tgtggatcgt tggcatccat tgtcagaagc
    19501 aacgaatgga caggaaaata tcttgctgat gaatgaagtt ggttatgatg cagcgacgat
    19561 aggaaacaat gaaggcgtag gaaattccaa agaagagttg aatcatttat acgatcatgc
    19621 tgagtttgat atcatcctgg ataacttatt cgataaaaat acgctccagc caccggcatg
    19681 gacgaaacca tataaaatca ttacaacgaa acaccagacg aaaatcggac taattgcatt
    19741 tactgctcca tttccgctta cttataatcc gaatggctgg gacatacgga atccttatga
    19801 tattttgcca gaattagtcg aagatttacg ttcacaagtg gatgttttag ttttgatgag
    19861 tcatctcggg attcaggatg atttccaaat tgcaaaagaa ataccagcaa ttgatgttat
    19921 tttaggatcg cacacccatc atttattcag agaaggtcac gtaatcaatg atgtccaaat
    19981 agcagccgct ggaaagtacg ggcagtatgt cggtgaagtc catttaacca tcgatgaaga
    20041 gaaaaaaatc cttaagcatt cagccaaagc catccctacc gaaacaatga cagcttttac
    20101 agaagatgaa caagaaataa atagttatct agaacgtggg catgaattat taaaagaaaa
    20161 agaagtagca gatttgccat tttctctgag tctagatatc ttcaatgagc attcgtttat
    20221 ccaagtagcc tttgaggcgg tgaaagaacg aggaaagacg gaagcagcaa tattaaacag
    20281 tggtctgttt ttaactgaaa ttccaaaagg gcgggtcaat caggatcagc ttcacactgc
    20341 gttgccgcat ccgatgcact tgttaaatgt cacattgggt ggaaatgatc tgatccgctt
    20401 agttttagaa atagaaaaaa atcgtaactt tttacgtaac tatcctatga agggaatggg
    20461 atttcgcggt aagatttttg ggcagatggt ctataatgga atcacatatg attctattaa
    20521 ccatcaagtc ttttggaaga acaagccaat cgatctgaat aaaaattata cttttactac
    20581 cgtagatcat ttgatgtttg ttccattttt tccaacgatt gagattgctg gaaaaaatga
    20641 atttttgttc cctgaattta tccgaagtgt ggtaggagat tacttgaaag ctcactaccc
    20701 aatcaaataa aaacaaggta taataaaaaa gataggtggt gaacgcatgt ctgcaaaaca
    20761 aaatgaacag cagaacgttg agcataaaac agaaattgct aagaaaaaat catcagctga
    20821 acaggaaaca acagtcaccg aagaactgac agctgctttg gaagaaatcg ttgaggagcc
    20881 taaagcagaa aaagtcaaag gcgagctagt gacactgtta gatgacagta attttttgat
    20941 aggtgaaaga cattatcggc ttgtgtccga ttatcgtgaa ggatttaatg cagaaaagct
    21001 tggagaacgt tacagtgatg tactagcccg atatgattat atcgtaggag attggggtta
    21061 tgaacaacta cgcctaaaag gatttttcca agcggataat cgacgggcgc atccagatca
    21121 gcgaatcgat tccttggaag actatcttta cgaatattgc aattttggtt gtgcgtattt
    21181 tgtcatcgag agaatcggcg gtaaaaaaga aaagacaact cagcgccgaa aaaagaaaaa
    21241 aaaccataat cgtgcgtata tcgatgagaa aaaaggacca gtcgcatcta atcgcaaaaa
    21301 accggttatt aaaaatcgaa aaacagagtc agcaaaaacc tctgaaaaag taaaaaaaca
    21361 agaacaacct aaacaagtag aaaaaacaaa aacagcattt acgatcagaa aaagggaaga
    21421 gtagtggatg aatggactat aaaggatatt taattgattt agacggaacg atttatcgtg
    21481 ggacacaacc cataccggcc ggtaaacgat ttgtggaaga attgcaaaaa agaaaattac
    21541 ctttcttgtt tgttaccaat aacacgacta agtcaccaga aacagtagct aatcgtctag
    21601 cagatgagtt tgacattcat gtagctccag agacagtcta cacagctact ttggcaacaa
    21661 tcgattttat gaaagcagat ggaaaaggga aaaaagtcta tgttatcgga gaagcaggat
    21721 tgattgactt gattttagct gccggattta catgggaaga agaggctcct gactatgtag
    21781 tggtaggctt agataattat ctgacctatg aaaaagtagt taaagcaaca cttgctattc
    21841 aaaaaggtgc tactttcatt ggaacgaacc cagataagaa tatacctact gaacgcggcc
    21901 ttcttcctgg agcagggtca gtcatctctt ttgtagagac agcaacccaa acgccgccga
    21961 tctacatcgg aaaaccagaa gccatcatta tggataaagc cgttgaagta ttagggctgc
    22021 aaaaagaaga agtaatcatg gttggagata actatgaaac agatatccaa gctgggatac
    22081 gcaataatat agatactttg ctcgttttat caggttttac aaaagaagaa gatgtacctg
    22141 ggttgcctat cccagctacc tatgtgaaac aatcactgga tgaatggagc ttctaatatg
    22201 aaaaattcga gatggcagtg gatggaatat gctggattgt tcagcctatt tctgacactg
    22261 atcagtctgg cagttggtgt gacgatcaac tttcgaccac tatacgtatt tgatatcgga
    22321 catttgcaaa ttttggatta tacttcttta gatcaagaga cgttactgaa aaattttgat
    22381 cacctaatga attatctcaa taatcccttc aaaaccatcc tcagcttgcc agatttccca
    22441 gtttctgcta gcggagccca tcacttttat gaagtgaaaa ttttgttttt agtggattat
    22501 gctgtgtttt tcatcacttt gatcccgagt attttgttta tcaaatattt gcaaaagaat
    22561 gatcggcttt ggcggttgat tcgtccgttt caaatcggca tgttactgcc agttgttttc
    22621 ggttttttca tgatgatagg atttgatcgc ttttttatcc tttttcatga aacgtttttc
    22681 aacaacgatg actggttatt cgatcccgtt actgatccaa tcatcaatgt acttccagaa
    22741 gaatttttca tgcatagctt tatcttattt tttgtattat tagaattatt ttttgctgtt
    22801 tttcttttct taggaaaaaa tagcttgaaa caaacaaaaa agaaagaact cgtctaaata
    22861 gacgttttct ttcttttttt gttgaattat tgagtaaggc gacttctttt ttctggttct
    22921 ttgtgtgcta atcgactggc agcagcagcg gcgatcgctc cgacgatatc atctaagaag
    22981 gtatggacat gaacgccatc gtggctgttt agttctttta aaataccagg tttcaccttg
    23041 tcgatataac cataattcgt aaagccgatc gtaccgtaaa cattcacgat tgacaaggct
    23101 aggatctcat cgataccgta aaggccttcg tcatcttcga taatatgttg caacggactc
    23161 atcaattttt tcttttctgc taatatatct aattggattc cagtgataat ggcgttatgt
    23221 acttcacgct ttgttagcac gctgttgaca ctttcagtac aatccgccaa agtcaaatca
    23281 gaaatatagt ctttttgtaa aaacatgaca agttgtgcga tatcttctac agttacgcca
    23341 cgttccttca atagttctct tgccttttct tctaaagtct cagttttgac gaccatatta
    23401 ttgctccccc tttatttttt ctttctctat ttcatgttaa cggaacatga aaaaaatgca
    23461 agaaactgct ttcgggttta acttgaaatg caaagagata taaaaaatca actaggacga
    23521 agatttttat cgtataagct tgtgctgtga ccaggctgag ttcgttcctt tggattaata
    23581 tagtgtaaag cgttgttcac tgcagtaggt gcttcaccga gcccagtagc aatcagtttc
    23641 acttttcctt cataggtaca gatgtcacca gctgcataaa cgcctggaat agaagtagac
    23701 atatctgatt ttacagtaat ggcatttctg gtactatcaa gtccccaaga agaaagatgt
    23761 tctaaattag aagagaatcc ataattgacg atcagagaat caatcatcaa atcaatcgtc
    23821 tcgtcacttt tcactttttt taaccggata tctgtcagtt ccccattatt gcctgataat
    23881 ccatcgatga gatagggagt aagcaagttg acagatgaag atttcaagcg tgatacacta
    23941 tgttcgtgcg cacgaaattc cgggcgacga tgaatcaagt aaacttcgct tgcaataggc
    24001 tctaacatca acgtccaatc gatagcagaa tcaccacctc cagcaatagc gacttttttt
    24061 ccagcatact tcatcaaatc attcacgaaa taatccaatc cgtggttttc aaatgattca
    24121 gcattatcta aattcaattt tcttggctgg aatgaaccat ttcctaaagc taaaatgact
    24181 gctttggaat aatggatgcc tttatttgta gtaatctcga taacttcgtc ttcacgagta
    24241 agcgagagaa cttcttcttt taaatggaat gtatggttaa aagtagttaa ttgtttttct
    24301 aattgatcga ttaattcact tgcttttatt gctggatacc caggaatatc gtaaatatat
    24361 ttttcgggat acaaagttgc taattgacca ccaagttgag gtagactgtc aatgattttt
    24421 gttttagctt ggcgcattcc tgcgtaaaaa gcggcaaaca tccctacagg acctgcaccg
    24481 atgattgtaa tgtcatagat ttccataaaa attcctccct tttcacacta tatcagaatt
    24541 taattgagaa tgcttctcaa aaatgtttga attcgaaatc gaaacggtaa gttatagaat
    24601 gtatctagtg atgaaaaata aaagaaaaca aatctagtat ttttacgaga ggttaggtat
    24661 tatgttatta ttattatgaa gtatgcaaat attaggagga aacaatatgg cattcccaca
    24721 actagattta aaaagtgaaa aaggaccaaa agctgttatc aaaacaaacc gtggtgacat
    24781 tactgttcaa ttattccctg aactagcacc gaagacggtt caaaatttca ttgaactttc
    24841 caaaaaaggt tattatgatg gcgtgatttt tcaccgcgtt attcctgatt tcatgatcca
    24901 aggcggcgat ccaactggaa caggaatggg tggcgaaagt atttatggcg aaagttttga
    24961 agatgaattc agtcgtgaac tgttcaacct tcgcggagct ttatctatgg caaattcagg
    25021 tccaaacaca aacggaagcc aattctttat tgtaaataac acaaatgtgc cagctaatat
    25081 gcttggacaa ctagaaggtg ctggattccc atcagaaatc attgaagcgt ataaaggtgg
    25141 cggaactcct tggctagatt tccgacatac agtctttgga catgtactag aagggatgga
    25201 cacagtagat gaaatcgcaa atgtacaacg tggtccacaa gaccgacctg tacatgatgt
    25261 agtgattgaa acaattgaaa tttcagaata gtttggtatg gtacggagta attatgaaaa
    25321 aggacgaaac ctagtaaggt ctcgtccttt tattttgaat aaatgattta atcgattgtc
    25381 tctaaagcat acttgattcg attaagtcct tccagtaaag tttcttctgg acaagcaata
    25441 ttcaagcgca tatgcccatg accggaagga ccaaacgtga tgccaggatt taatacgact
    25501 tttcctttcc gaacaagagt gttctccaat tcttggtcgt ctgaaatata ggcggtaaaa
    25561 tctaaccaca ttaagtaagt tccttcaggg ttcattattc tcactttcgg aagatactgt
    25621 tcaaaaaact gattaactgt ttgaacattt ttttctagat aaggaatcag ttggcttaac
    25681 cattctccac ccgtctcata agccgcttgg gttccaatca gtccaaaagt gttgatttcg
    25741 tgctgttggt tcatcactaa atgtttttca aaatcagctt tcatctctgg atttttgata
    25801 aataccattg aatttttgat tgcagctaga ttgaaagtct tggttgcgga agtaaaagca
    25861 actagtagat catctaaatt aggatcaatc gttagcatgg aagtaaatgt atgatcgaat
    25921 aaagttaaat cttgatggat ctcgtcacta aacagaatca cttgatgttt taaacacaat
    25981 tcgcttaact gtttcaattc ttctttgctc caaacacgcc ctccaggatt gtgaggattg
    26041 cataaaatca ttgcttttac attgttttct tcgatttttt tctccatgtc agacaagtcc
    26101 atgatgaaat gattattttt ttctagcaaa gagcttcgaa cgatgtgacg ttgatttgtt
    26161 tctataatag aggaaaatgg aggataaact gggtcatgaa tcaaaataga atcgcctggt
    26221 tttgtaaaag tttgtactgc tgcagctaaa ctggttaaca caccacttgt aaaaacgata
    26281 ttttctttcg tcaactccac agcatggtgt tggcgttccc aatgaatgat agcctgatat
    26341 agtttatcag acagagtggc ataaccaaag attccatgtt tgatgtattc actaaacgct
    26401 ttagctaccc caccgggaga caagaagtcc atatctgcta cccacaaagg aagtaagtca
    26461 tccatttgat atgtctcagc aattgcgtcc cattttacac tttctgtatc ttttcttgaa
    26521 atctgtttat caaattcgat catcttaaga cctccagtca ttttcgtcgc ttcttttttt
    26581 gagctattta cagtataatg ataaatgcga agagagggaa gtagatgact tataaaattg
    26641 gacaaataat tgaaggaaaa gtgacaggga tacagcctta tggcgcattc gtttctcttg
    26701 ataacgagac gcaaggactt attcatgttt cagaagtaca atccggttat acgaaaaata
    26761 tccattcatt gttaaaagtc ggacagccag taacagttca gatcatcgac attgatgaat
    26821 attccaaaaa aatcagttta tctttaagaa cgttagaaaa aacaaatcca gctgttccat
    26881 atcgcagaaa aaggtatttc acgaataaaa atcgtaagat cggatttacc actattgcgg
    26941 agcagttacc tatttggata gaagaagcat tatctgaact agaacggaaa gaaaataaga
    27001 aataaaaagt gtattttttc tgaaaatgtg ctagaatttt tatgtaagcc atagaacaag
    27061 ttgatcgagg tggaaatttt ggcaagcaaa agagttgctg gtacaattat gttgcatttg
    27121 gaggatggta ctaaaaaatt tttggtccat tcaattgatg acaagttgga atttgcgtta
    27181 gcggaacttt ctgaaggaaa gactggttta gcgaatatac ttaatttctt aaaagaaata
    27241 gttcatatcg atgttagcaa gattagtttg atggaattga caaatacaca tattaaagag
    27301 gaaaatgttc cgttgtttgt ctttgaaact gaacaaaaga atcaaagaga agaattaggc
    27361 gaaggatata tttgggaaga accaggtcaa atgcgctctg ttcttggaac ttacgaagta
    27421 gagggagtgc ctttcttcta aaatacagat taagcgaaca aagaagtttg aatttttttc
    27481 aaacttcttt ttttattgtt tggtccaaaa aatacaatga aatgttctgc taaagatagt
    27541 tttttagtgc attttatttt caaaatatgt tgaaaacggt tgtataacga ataataataa
    27601 tt
//
LOCUS       DAMEEU010000035        27232 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.036, whole genome shotgun sequence.
ACCESSION   DAMEEU010000035 DAMEEU010000000
VERSION     DAMEEU010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 27232)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27232)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27232
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.036"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(161..445)
                     /locus_tag="PB779_001487"
     CDS             complement(161..445)
                     /locus_tag="PB779_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739015.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(463..1353)
                     /locus_tag="PB779_001488"
     CDS             complement(463..1353)
                     /locus_tag="PB779_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HDE0739016.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(1373..1591)
                     /locus_tag="PB779_001489"
     CDS             complement(1373..1591)
                     /locus_tag="PB779_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HDE0739017.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(1561..3261)
                     /locus_tag="PB779_001490"
     CDS             complement(1561..3261)
                     /locus_tag="PB779_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HDE0739018.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            3528..4301
                     /locus_tag="PB779_001491"
     CDS             3528..4301
                     /locus_tag="PB779_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739019.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="PB779_001492"
     CDS             complement(4382..4951)
                     /gene="thiT"
                     /locus_tag="PB779_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HDE0739020.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNPWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(5017..5119)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(5125..6096)
                     /locus_tag="PB779_001493"
     CDS             complement(5125..6096)
                     /locus_tag="PB779_001493"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HDE0739021.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="PB779_001494"
     CDS             complement(6190..7563)
                     /gene="glmU"
                     /locus_tag="PB779_001494"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HDE0739022.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(8066..8884)
                     /gene="purR"
                     /locus_tag="PB779_001495"
     CDS             complement(8066..8884)
                     /gene="purR"
                     /locus_tag="PB779_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HDE0739023.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(9051..9875)
                     /locus_tag="PB779_001496"
     CDS             complement(9051..9875)
                     /locus_tag="PB779_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDE0739024.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(9848..10528)
                     /locus_tag="PB779_001497"
     CDS             complement(9848..10528)
                     /locus_tag="PB779_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDE0739025.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(10551..11489)
                     /locus_tag="PB779_001498"
     CDS             complement(10551..11489)
                     /locus_tag="PB779_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HDE0739026.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(11734..12597)
                     /locus_tag="PB779_001499"
     CDS             complement(11734..12597)
                     /locus_tag="PB779_001499"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HDE0739027.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="PB779_001500"
     CDS             complement(12739..15312)
                     /gene="mprF"
                     /locus_tag="PB779_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HDE0739028.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLP
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            15453..16259
                     /gene="proC"
                     /locus_tag="PB779_001501"
     CDS             15453..16259
                     /gene="proC"
                     /locus_tag="PB779_001501"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HDE0739029.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
     gene            complement(16338..17894)
                     /gene="rny"
                     /locus_tag="PB779_001502"
     CDS             complement(16338..17894)
                     /gene="rny"
                     /locus_tag="PB779_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HDE0739030.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELGEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(18305..19354)
                     /gene="recA"
                     /locus_tag="PB779_001503"
     CDS             complement(18305..19354)
                     /gene="recA"
                     /locus_tag="PB779_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HDE0739031.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(19463..20704)
                     /locus_tag="PB779_001504"
     CDS             complement(19463..20704)
                     /locus_tag="PB779_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HDE0739032.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="PB779_001505"
     CDS             complement(20944..21522)
                     /gene="pgsA"
                     /locus_tag="PB779_001505"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HDE0739033.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(21731..22654)
                     /locus_tag="PB779_001506"
     CDS             complement(21731..22654)
                     /locus_tag="PB779_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739034.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(23392..24678)
                     /locus_tag="PB779_001507"
     CDS             complement(23392..24678)
                     /locus_tag="PB779_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDE0739035.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(24671..25939)
                     /locus_tag="PB779_001508"
     CDS             complement(24671..25939)
                     /locus_tag="PB779_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HDE0739036.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            26191..26652
                     /gene="mscL"
                     /locus_tag="PB779_001509"
     CDS             26191..26652
                     /gene="mscL"
                     /locus_tag="PB779_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HDE0739037.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(26711..27157)
                     /locus_tag="PB779_001510"
     CDS             complement(26711..27157)
                     /locus_tag="PB779_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739038.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
BASE COUNT         7741 a         5873 c         4723 g         8895 t
ORIGIN      
        1 taataccgag aaaatggttt ttgaacatca cttattcaaa ataaaaaaag attgtgacac
       61 gaattttgtc acaaccttta aatgtattcc tagagcaaag aagctaagcg aagaaatcca
      121 attctgatta tttattgtat ttctttgttc agcatccttg ctaaaagccc atattggaca
      181 aagtattcac tacacccatg atctcatctt ttcgagaacg tgctttttct gtcggatctt
      241 ctacctcttc tgtgtcaatt cgaacaataa atttccgatt catcgtcacg taagcaccgt
      301 cgttgatcaa aataaacagt tcgttctcat tatagtctgc acaggcatct ttccatacgt
      361 caaagccgtt tttttcagaa gggatatccc gtttaaccac agtttttcca cttaattcgt
      421 ggaacgttac gtcataatat ttcattatct ctacctcttt cgtcattcaa tattttgtac
      481 ttgttctctg attttttcta agatcgtctt agactggacg acttgatttt taatttcgat
      541 tgcatttgat ttggaaccga tcgtgttgat ttcccgattc atttcttgga tcaggaaatc
      601 taattcccga cctacaggac attgtgcttc gataagttca tctagttttt gtacatggat
      661 cgccagacga tccagttcct cgtgaatatc tccgcgttcc aacaagatgg ctagctccgt
      721 caacaaccgt tgctcatcga ctttcgctcc aagaaattcc tccagctttt tttgatacct
      781 tatttgaaat tccttttcat agatttctac aaaactatcg agttttttta gtacttcttt
      841 gaattcttca gtattctttt tcaacactaa agctaaagct tgaccttctt tttctcgact
      901 cgcctcaata gaatcaagtg cgcttttcaa tgtatctaga gctaactgtg ccaattcttc
      961 catgctctct tccggttttt cttctaccgt tacgaagttt tcgtccagcg cgaagcgttc
     1021 cgccatccga ctaattgaca cttgattttg actaccgtat cgttgttgaa ttccgtctgt
     1081 caattgagtg ataagtgaat caatcaattc ccagttgatg acgatctgtt tttcgttttt
     1141 gccaatataa gctagattca caaatacttc gattcgaccg cggcttaact gctgtttaat
     1201 aagctgacga aaatcgtttt caacaaagtt caggatttta ggacttcgta tttgaacatc
     1261 tagaaaacgc tggttgacac tttttatttc aatatctaac tgatacgctt ttgtttcgcg
     1321 gatggctttg ccaaaaccag tcatactttt cattcgacag ggtccttcct cattacatat
     1381 tttctattgc tttttgcagt tgttcaaact cttcgttcgt caatgtcagg cctttcccca
     1441 ttttttcatg gtctggcgcc caatctcgaa gatcgaattt tggcgggcga ccattccagc
     1501 tgactaggtt cagttcttta cgccacccct tgttgttttc tgacaatata gcgatttctt
     1561 ctacgatttc atatgaaaat tcttgtgcca tggttgttcc tccttgagat aatataaata
     1621 taggatcagt aatgtgtcaa ctggttgctt aagcaattca tgctgcaaac gatccttgcg
     1681 ttttccttgt agcagataat caaaataaac agttttcgtg cgctcatttt gtattttttg
     1741 ctggtatttt cgataccttc gccattcttc agtacttaat tgaccaattt gtgccaataa
     1801 atcatccggc atacttttta tatcttgttg gcagatcatt tgaatcatca tgtctacttg
     1861 atagatttca ttgggcagta aaaaatgttt ttttgctaaa agttctagca tcgccaatcc
     1921 gcatgtctct ggtacgaccc tgttcttata taaattacgc agtttttgcc aaaattttat
     1981 gcttttgaaa aaagataatt ctaactgaat ttcttttgtt aagtaagaca aaaatcctcg
     2041 ccagtatgtt cttgcaggtt taacagaatg aaatgtatac cagttcccat agtaatagcc
     2101 taatcgtttt ttcatttcca gatagcctaa ttgtaaattt aattggttcc tttggctatc
     2161 aaaaagcaga aagctgccta gtgtccacaa tgtttgacat ttccaatgga taaaaatgtc
     2221 tggcatacga atttttttcg ctgggcctgg cccttgcaca tctacgacaa atgcctctgt
     2281 tgctcctttg ttaatcgcaa tatcaatagg tattttgttg cgatacccac cgtctgcata
     2341 tttatttttt ccgatctttc gataagccat agcgggataa aatgaagcag aggcgagtat
     2401 ccaatctggt atttcttctg tttttgtctg ttggatatca gtcactactt ccgctagttc
     2461 tggcagttta gtagacaccg tatataaacg tattttggga ttatgtttga gtaaggacaa
     2521 atccaaattg tctttgacca tcttttccaa tggagcagaa gaaaccccgc cttcaattag
     2581 tgctgttttc gtcatttggc gtctttctcg atagaagcgt tcacgaaggt cttcaactgc
     2641 agccatttct ggtaacgcaa gcacttgtct tgtcgacagc tttttccata aattcacagc
     2701 ttttttcata tctccttgta aaatcaatgc gccgttcaac gcacctaccg aggtacctgt
     2761 gataatctca aagttgatat catgttcctt cagcgcctgc cacacaccaa tctgataagc
     2821 accgtgcgct cctcctccac ctaaaacaag tgctgtatga tagaccagct ttttatttaa
     2881 ttgtgtggtt ccttgatagc cgtttttatg aaaaatacgc aaccattctt ctgatagagg
     2941 agattgaaat aaaaaacaac agttttcttt aataaaaaaa cgagcgcaag cttccatata
     3001 ccgaaaaaat tttttccatt caaaagtttc accttcaatc aacagattat taaaaataac
     3061 atctcctcta cttttagcaa tagtaaaata gacggtatat tttttcgata ctgctttaaa
     3121 agcacattgc ttttttgcag aacgccaaaa agcgtctcta ctttcttgat gactttgaaa
     3181 aaatggaagg ggttgttttg cttgctggat aggcgaatac agcgacattt tctgtgaaaa
     3241 gtaaactttt tttatctcca tcgcgctctc ctttttcttc aagtatacca gtacgtcata
     3301 aaaaggtcat gagtctcgta ttcgactttg tagattccat aagaaaacaa ttcataaaac
     3361 ctcctttaaa taaaaaaata caaaaatcac aaaaattaat tgaaaatgag agtgttttca
     3421 atgaaaacgt gattttgtaa tggaatttta aaataaaaga aacaagcttt tttaatgcaa
     3481 atgttgtaaa ataaaagaga ttaagaggaa ataagaggag gaacatgatg actgagtcag
     3541 tttatgtaca tattgatacc acaagtaatg ctgttttaac aaaagggctg actgctactg
     3601 actttgcaaa cagtatcgtg cattttcctc aaaacttgct cttgcttgat ccatctgctt
     3661 ctgctggaga atatgaatcc catacagggc tgaaagtaat ccgtggtaca gaaaatattc
     3721 agcgtttctt ttcctcttct cgtaacaggc gtggattcga tgaattgaag tggatcgact
     3781 ttactgattt aacgatgctg aaagaattga cacctttaga aatttcagaa ttattatatt
     3841 ttggtcatat gaaaacacat cttcattcgc cgttttttta taaactacag aataattttg
     3901 tatacttcga tcttaatgat cagctgaatc ggatttatta tcgctattta gatgaatttt
     3961 ataggatttt tgctagtaaa ttaagttcga tcttgtcaga taagatcaat gtaaaaaaat
     4021 cttttttcaa aaaagaaaca cctgttgaaa aaatcagtgt ggaattattg aaagaaatgc
     4081 gtaatttgat gcaggaaggg atcatttttt cttttgatca agttggtttg atcgatggta
     4141 aatatcgtat cccaatctat gtgattgaag attatatttg gaaattaaaa ggcacccggt
     4201 atcgagaaga ggaaatcatc gctactttaa tctactctgt caccgatcga cactggcaat
     4261 tggtagaaga tgccgatctt tcttatctgc cattgaagta gatctatttc ttatcaaaaa
     4321 ataaaaagga aacaagaaac taggacatga ttctgtctca agtttcttgc ttctttttta
     4381 tttacagctc ctgtcgttta tctggcacaa aaatcgaagg agtcgtttgt tggatcccta
     4441 ataaaacgat gatcgttaca atagctgtac tcaacccgct ggcaccattc attacgaaag
     4501 aaaagagcca aggattcatc ccccatagtg catacgctcc ccagaaaacc actcctgcaa
     4561 taaaatgcca aaaatatctg gaaagtgcgc caatcaatgc accaaacacg atgctttttc
     4621 taatttgttt cgtattatcg tctacatagc ctttttggac atttgaagcc atgagccctg
     4681 ctgcgcctgc aaaagtatag gcaatcgggt actcaatcaa cacttgaacg acacttaaat
     4741 aataaacttg tcccaacgga aaatgtagga tgccccaaat gaaacctgcc agcatccctg
     4801 cctttgtccc tcttcttaac gcaaaaagag tcaatggaat ctgccctaat gaaatagaaa
     4861 aactgctgcc gatctggatc ggaatcaacg acaacaccat cgctaacgct gcaacaatcg
     4921 ttccttctac ccaaactcta ttttttccca taaaaaaact tcctcctttg aataaaaaag
     4981 tcacaaagga ggaagcagct ttcgaaaata gtcaaacagc tgtttattca caattcctac
     5041 gctcgcataa ccgatacagg tacgaagggt ttagaaatag attcaatctc agcccaattg
     5101 gactcccctt tgtgagttta tttattattt attttttgtt tcaaacaatg gactaactgg
     5161 tttgttttca tggatacgtt tgattgcatc tcccattagt ccgccaacac ttacttcatc
     5221 gattttgtcg attttacgat cttctggaag atagatcgag tctgtaacaa ctagacgctc
     5281 gatagctgaa tcttctattc tttgtaaagc agggccggat aatactggat gtgtacatga
     5341 agcatacaca ctagttgcac cagcttcttt caaagcattg gcagccaatg tgatcgtacc
     5401 tgctgtatcg atcatatcat cgatcagtac acaagttttg cctttgactt gtccaatgat
     5461 attcattact tctgcaacat ttgcttttgg acggcgtttg tctatgatcg caatcggaga
     5521 tttcaaaaat tccgctaatt tacgtgcccg tgtgacacca ccatggtctg gtgaaacaac
     5581 gacaacatca tcgcctttga ttcctttttc taagaaataa ttggcaataa gtggcgcacc
     5641 catcaaatga tcgactggaa tatcaaagaa accttggatt tgaactgcat gaaggtccaa
     5701 agtcagcatt cttgttgcac cagctttttg aatcatgttt gctactaatt tcgctgtgat
     5761 tggttcccgt gcacgtgctt tacggtcttg acgcgcatag ccataataag gcatgactac
     5821 gttgattgtt tttgcacttg ctcgtttcag tgcgtcaatc atgatcagca actccatcaa
     5881 gttatcattg actgggctgc tcgttgattg aataacatag acatgcgatc cacgaatact
     5941 ttcttcaatg tttacttgaa tttctccatc actaaattga gtaacagatg attttcctaa
     6001 ctcgacgccg actgctgctg caattttctc tgctaatggg cgattggaat ttaacgcaaa
     6061 aatttttaat cttgggtcaa agtaatgttt tgacatgggg acctccactt tctttttcac
     6121 aactctagaa ttctacctaa taaatagtag tcatattttt taaataaatc aagtgatttt
     6181 gcaaaagtct tagtttagat aagggagttt ttttgcatat ccttctttat tgacttgtct
     6241 tgctctcgca attgccagcg catattctgg aatattgtct gtaattgttg acccggcagc
     6301 aatcgaactg tttttagcta cctcgacagg tccgatgata ttcgtgctag aaccaataaa
     6361 gctgtggtcg ccgacagtcg tatgatgttt gttctttcca tcatagttga cgaagacaac
     6421 accacatccg acattgattt cttctcccag cgtagcatca ccaacataag tcaagtgacc
     6481 gactttagtt cctttgccga tttgagcatt tttcacttcc acaaagtttc cgatatggac
     6541 gttttcgcca atttcagctt ttggtcgtaa atgtgcataa ggtcccacat ctgcatgttt
     6601 cttgacatgg ctgctttcaa tgactgagtt ttcaatgacg acgtgatcct caatcctact
     6661 gtctacgatt tttgaatgtg acccgatgac acaatcagaa ccaatgactg tatttccttg
     6721 gatttgtaca cctgcttcga tcaatgtgtc tggaccgatt tctacgcctg catcgatgta
     6781 tgtcgttgct gaatcgacaa agcttacgcc attgaccata tgcatctggt taattcgctt
     6841 tctcatgatc tcatttgctt tagctaacgc gatccgatca ttgactccca ttgattcttc
     6901 aaaatcatcc gtttgataag cagcaactgt atggccttct tcttttaaga tttcgatgat
     6961 atctgttaga tagtattcac cttgagcatt gtttgttcca actttgctta acgcatcgaa
     7021 caaagcttcg ttgtcaaaac agtaagttcc tgtattgatt tcttgtacaa gagcttcttc
     7081 tggtgttgca tctttttgtt ccacgatttt ttctacgatc ccaatatggt cacggatgat
     7141 tcgtccatat cctgttgggt tttctgcttg tgccgtcaag atcgttgcac ttgcattttt
     7201 tccttggtga tattcaaaaa gattgttcag cgtttcagta gtcaataatg gtgtatcgcc
     7261 actgataact aacgttgttc ctttttttcc ttccaagaaa gaagcagctt gcaaaacagc
     7321 atgtcctgtt cccaattgtt ctgcttgtaa cgcatattta ctgcgttctc ctagttgtgc
     7381 tttaacttgt tctgctccgt gtccaacgat cgtaatcact tcatctggtt tcgtttcact
     7441 gacccgatta atgatatgtt ctaccatagg tttaccagaa acgggatgta aaactttata
     7501 taattttgac ttcatgcggg tacctttccc tgccgccaaa ataattgcat aacgtgcgtc
     7561 caactgcgtc actcctaaat atagtttgct gatttcagtt tatcccagta tacccatttt
     7621 ttcaacaaaa caagtgattt tcttttatcc cagcgttttc tggataaaaa aatagataga
     7681 ccataacggg cctatctatt tggtaaccgg tgctctcctg ccaactcctc ggtcacaagt
     7741 cacactactc ataaaacatg aaaagctgtt ttttgaaatc gtttcttgtg acttagagtt
     7801 aaacggtagg cttacaacct cttcattaaa cgtttttcaa tcagctgacc ttcggtatta
     7861 gctcaataaa cggcaaaata tgaggagcaa tttttccgtt tattgagcta atactcagga
     7921 caggacgctg atttcacaac ctctagataa acggtgttca aaagccagtt tctcggtatt
     7981 aagccaaatt tatgaaaaaa tgtggaaagc cattttcaca aaatttttct tactactcga
     8041 aactaagcag ctttttcaca acctcttatt ctgaaaaata atttcctggc acaaccgtaa
     8101 tatttttcgt ttgagtatct acatctttga cataaagcag tgacgtataa tcatcgatgg
     8161 cgcgatgacc gttgaatttt gattcggcaa atacagtgat gccaacaagt tctgattcga
     8221 attcttcaat caagctcttc attccgttga ctgttccgcc gcctttcatg aaatcatcca
     8281 ctacaaggac acgtgaacca cgtttcaaac ttctcttaga cagttccatc ttttcaattc
     8341 tttcagaaga tccagacaca tagttgacac ttactgttga tccttctgtt atttttgagt
     8401 cccggcgtac aataacgaat ggcgcattca gataatagga cacagcttgg gcaataggta
     8461 cgccttttgt ggctacagtc attacagcat cgattttttc accaaggtat ttagaagcaa
     8521 tgattcttcc aacttgacgc agcagttcag gttctcctaa caaatcagag agataaacat
     8581 atcctcctgg aagcagacgg tcttgttctg atagacgttc tgctagagat tcaatatatt
     8641 ttttcgcctc ttcatatgaa atttcaggga tgaacaatac accacctgca gcacccggga
     8701 ttgtttccaa ggttccatac cctcgttctt taaatgtttt cttgatgatt cccaaatctt
     8761 cactgataga agatttagca gattcataac gttcggcaaa gcttgttaag gaaatcaatt
     8821 catgcgggtg attcaataaa tactgtgtca tgtcaactag acgttcactg cgacgtactt
     8881 tcacctattc caactccttt taagaaattt tatcgtttta cattatataa gtttttcttc
     8941 aaaaattcga gcattttatg aaaaaataag aaaatagttc ggtatttatt aaaataaaaa
     9001 gaagcctata aaaaattttt cgtttttata aggcttcttt tctttataat ttagttattt
     9061 tttcttctga aggcaaccaa tattcgtttg atgatattta caatcaggaa caaagcaata
     9121 aagactaatg tgattgttgc tcctggaggt gtatctagat aaaacgagct agttagtcct
     9181 gacagcatcc ctagaaatcc tacacaaaca ctgatagcaa tcacgacatt gaagcttttg
     9241 cctaatcgca taccgattgc tgcgggaaga accatgattg cggatatcaa aagtgcaccg
     9301 gcaatcggga tcatcacagc aatagccaca ccagtaatca cattgaacat catcgacatc
     9361 aaatgaacgg gtagcccatc cacgtgggcg gtatcttcat caaaagtcag aacatacatc
     9421 ggccgtttga ataaaaagaa caatataccg atggcaacga ataagattcc taaaaagatg
     9481 acttgctccc atgtaatggt cacgatcgaa ccaaacagat aggattggat acttgttgct
     9541 gaattccctc cgctcaaatt catcaatact aacgctagcg ccaaaccacc agccattaaa
     9601 atggcaatgg agatttctga ataggttcgg tagatcgttc gcagatactc caatatcaca
     9661 gctgctaata caacgactag catggtcgta agtgtaggat taaggttcaa aaagaatcct
     9721 aacgctaccc ctgctaaaga gacatgagaa agcgtatcag ccatcagcga ttgtcttctg
     9781 atcactaaaa acacacctag catcggggcg attccggcaa tgaagatagc ggcaagaaac
     9841 gctcttctca tgaattcata tgaaagcaac gccattgaga atcctccttt ctcaccagtc
     9901 ggatctgtct gtccgcatac tgtttgatat cttcatgatc atgggtgatc attagaactg
     9961 atttcccatg gacatgcgca ctatgtcgga gaagacgata aaattcattt ctggattctt
    10021 catccatacc tgttgttggt tcatcaagaa caaataagtc agggtcagta gcaaaaatac
    10081 gcgctaaact gattcgctgc ttttgtccgc cagacaattc acctattcgc cgatttcgca
    10141 tatcccacat ccctacagct tctaaagcac gctgtacatg ttgatgatct ttttcagaga
    10201 gacgcttgaa ccagcggcct cttggatatc ttcctgaacg gactaattcg atcaccgtac
    10261 taggaaaacc tgcattgaaa gatgcaactt gttgaggaat ataaccgata cttaattttt
    10321 ttccttcttg atttttctca gcaatcttta tcattccttt tgaaggtttc agtaatccta
    10381 acgatgcttt caccaaggtt gacttggctg ctccattttc tccagttaaa atgacaaatt
    10441 cacccgcatc tacatgataa gagacatctt ctagtacagg ttcatcatca tagtaaaagg
    10501 tcaaatcaga tatttcgata taacgcacct tacaacctcc attctaaaac ttaattgata
    10561 ctttctttta aagctttcag atttttttcc atgacagaaa tataattttc gcctgctttg
    10621 atttgttcat tagtcaagct ttctaaagga ttcaacactt ctagcttcac tcctgtttca
    10681 ttcgacaatg tctcagctac cttcgaagag gcattttctt caaaataaat cactttgatg
    10741 ttgtttttct tcacaaattc ttttagctca gctaagcgac ttggtgtggg ttcctgatct
    10801 ggtgaaacgc ccgaaatcgc tacttgtttt aagtcgtatt gattcgctaa ataagcaaaa
    10861 gcagcatgct gagtgacaaa tgtgcggttt gttgcatctt ttagctcatc ggagtatttt
    10921 tgatccagtg cttcaagctt tttgatataa gcatcggcat tcttcgtaaa agtttccttt
    10981 ttatctggat atttttcgcc taattcttca gcaatcgttc tgacttcttt tatagctaat
    11041 accggatcga gccaaacatg tggatcgtat tcatgtgaat gaccatgccc ttcttctgat
    11101 tcttcatgtt cgtctgcttc ttgcgattct aaacggtcga ttcctttagc tgcttcgatc
    11161 atcaaggtct gtttgctatc cactgaatcc tttaacgaat ccacaaaaaa ttccatgtct
    11221 gaactattat acacgaaaac atctgcatcg gaaatttctg ctctttcttt tgcacttggt
    11281 tcgaaatcat gcggctccgt tccagcaggg atcaaaagtt tcacgtttcc ttcatcccct
    11341 acgatctctt ttgtaaaatc atacatcgga taaaaagtcg taacgatcgt caaatcctct
    11401 tttttgtctg cttccttgtt cgtatttcca catgctgcaa acagtaaagc acctatcatt
    11461 accgtagctg tcaaaagata ttttttcatt tatatgctcc tttcaatgaa caaatcggaa
    11521 ttttacgatt tattaacgtg aactaatgta tcaaaataaa aaaacacagt caatagaaat
    11581 ccatcaattt ctgatttaag catgtatatt cttgattaaa tcgtaaaatg gatgagttgc
    11641 tgctcatatc tagccatttc actacaataa aaaactgaag aataccattt taggattcct
    11701 cagtttttca tcacctattt tacttcttat attttattgc agggttcgta ctaaataaac
    11761 ttcctcacaa aaacctttta acccattata tactctctgc gctcttgaat aatgttgaca
    11821 caaggcaaaa acggttggtc cgcttccact catcaatgca gcatctgctc cgtacttgat
    11881 catacgctct ttgatttgat ggatgactgg atgccgcttt cccgttatat cttctaaact
    11941 gtttcccatt tttttgatca tctgctgata atcttgctct cggatggctt cagcaagtcc
    12001 gtggatgtct tgatgttgga tggcttgcgt atctacttct ctaaacactg tacgtgtaga
    12061 gacactcatt cttggtttga ccaacacaac ccagcactgt ggcatagaag gtaatacttg
    12121 gatttcttcc cctttgccac cgacaaatgc cgtacttccg tagacacagt aaggaacatc
    12181 tgtaccgact tccaaaccga tttctgccag ttcttctaac gaacagccca gattccataa
    12241 ttggttgatc cctcttagag cagctgcaca gtctgtactt cctccgccta atccagctgc
    12301 tactggaata ttcttcttaa caaagatctt gacaccggtt ttgatattgt atttattttt
    12361 tagcaataaa gcagcttgat aaacattgtt ccgttcatct accggtaaaa atgctttatt
    12421 tgtttctaca atgattttgt cttctgttat ttcttcaaaa aatagatgat ctgccaagtc
    12481 tacgctcgac atcaccattt ccaactcatg atacccatct tgccgtctat ataatacatc
    12541 cagtcctaaa tttatcttgg ctggcgcttt ttcaatcaat tccatcctct cacccattcg
    12601 aaaagtctaa gtcgcaagta ttctatcata gggaaaaata aaagtatagc ttatgtctgc
    12661 ctagtggttg attttgtcat cgtttcaaca gctttcacag aattttctct tcataatcca
    12721 aacaagttct agtgattctt ataattctgt gagcacttct tctgccaaac tcggaacatt
    12781 tcctttttct tttcctatca gactgagtag ctgcatggta gcaaatccga aattacttcc
    12841 tttcctataa gcaaaataac gtccttccca atgatcgaca tattttaatt tcttttcata
    12901 agcagactgg aaggaataga aaaaattacc ataattatat acgatatgca tgactttttc
    12961 ttgaaagaaa gaaaaatctg tttctccaac attagctaat ggagctaagc ctagattggc
    13021 ttccgagtag cccattttct cgtatacaat aaacagattg gctaacagat agtcagctaa
    13081 ttcctcagat tctttaggta agacccgcaa caaatcatat cccgcctgct tcttcgtcat
    13141 cggctgagcg gtgatgaagc caacgacttt ttgatcttta cggacaatac cgacaccgct
    13201 agataataca tatgatttat caaatcgtcc cacagagaag tatttttctc gtgcaccttg
    13261 aagccatttt tgtgaaactt catttacagc ttgatgtaat tcttccggca gttgatcgta
    13321 ccaagtaaaa tggtatcctt ctttcatcaa acgttgatat tcaagttgct gactcagccg
    13381 agacaagtct tctgttgcta gatcaacaat ccctgcttca cctactttcg tgaagtgaaa
    13441 acccaattca tgaagcatca ctacgtagct ttctgatatc ttataaaacg caagctgata
    13501 gcctaaacaa tctgcttgtt tcataaactg attcgttgct gcccgcatca ttttaggatt
    13561 gccaactgga tctcctaaaa caaagcattt gtttcctttg atctgataac caaaaacgac
    13621 ttgatcttgg tcgtcttctt ggtaataaaa ataactgtaa cctgacaagc gaagctgatg
    13681 gcttgtagct gtgcctccgt atgtttccaa taaacggtca aaacggtctt tttcgtactc
    13741 actgccaagc ttcgtagtat cttcagctaa atattgataa agcgccacta aagctagcaa
    13801 tgagatgccc aaaccaataa gccctgagaa ccacacatca tctgaaggaa acaaaataaa
    13861 atgatttcct gttattcgac cgactaaaaa gcgtccgctg tgatagcctg caattgcgta
    13921 aacgataaac aaaaagccga acaagctagc atcaaagatt atagctcccc aagaataaac
    13981 gaattttgtt cgataaaatt cttttctgga taaccacaca gctaacagaa tcaagacata
    14041 taccaatatc aactgccaag ataacgtacg tgtgattgta tttaaaatac caaaagatag
    14101 taaagcaatc gtaggcagaa atgccttttt gacttttact gaaagtgctc tagcaaggcc
    14161 gagtaataaa aagccaacca atagattcac tgtctgatct aaaaaattga atgagaacgg
    14221 caataatact tgaaatagcc gactgattgc agacagatta gtgattgttg atagaagtac
    14281 catcatgatc cccgcaaaat agacagcact tacgagcacg atatgcgcaa ccttttggaa
    14341 aaacagtcgc ggaatgttat ctaaaaatcg attgattttg actcctgtat gtgtgatgaa
    14401 caatagaagt cccgtcataa aaggtagaac ataataaaac aaccgataat ataatagcca
    14461 aactactgct acatcttgcc gaacaggcaa ttgactcatt cctaagatca tcaaaacgtc
    14521 aaaagtcccc attccacctg ggaccatcgt cagcattcct atcaatgtag caatcatgaa
    14581 cataggatag atcgaaagca tcgaaatatc tattctcatc aacttgccga tgatcaaaaa
    14641 taccgcaagg gctcccgtcc attgtccaaa ggatgccagt agcagaccaa gcaagccttt
    14701 tggataaaac tcgaagaaca atgtctttct ctttagataa gcaaaaaaga aaatgactgg
    14761 tgctaaaaaa ctaccgccga aaagccagat ccaatagctt cgaaaaatac tttctgactg
    14821 aataaaaaag acatcaataa atgtaagaaa cgaccataca gacaaaccag tcagcataaa
    14881 tagtgcgact tttgatacag tggctaaaac catttttcta tttgtctgct ttccataaaa
    14941 actagcccgc agacttgctc ctaccacacc accaaaaccg gcgagattgt tgatcgtgtt
    15001 tgttacccac gcagcaagaa gaaactcttt tctttccatt tttggttttc cttgtttttc
    15061 taagactctg atcgtcaccc aatcatacaa caacatcgga gtgacaccca gcagtccagc
    15121 cagaatcatg agcaggatcg tcatgcggct ttgttgtccc atcctttgcc aaatatcttg
    15181 ccaactcatg ccattagcaa tatttgcgac ttgatttgcc acaaagacta acacggagcc
    15241 gaaaaaaatc agttttaaaa tcagactatg ttcctttatc cattgcagca tcaagtatcg
    15301 tttatttttc acattttccc attcctaact tgtatacttt tgtgtcatac cccaatgtta
    15361 tcttatttat tttaattttt ccactttaga cctgttcttt gcttgcgatg atagaaaaag
    15421 aaagatatcc taatgctaaa ggagaggata acatgaaagt aggatttatc ggcacaggga
    15481 atatggcaca agctattatt gatggtttat taaaaaaagg aacagtctcg aaagaagagg
    15541 tgttcgtttc cagtggacat tttgaaaatg cacaaaaatt tgctgctgaa actggcgtcc
    15601 atgcatgcaa aagtaatcag gaagttgcat cacaatcaga tatcgttctt ttagccgtga
    15661 aaccaaaaat cattgaaaaa gtattggaag aactaagaga atatagccag aaagtcttat
    15721 tcatttctat tgcttcagga aaatcattaa cagatttaga aacagcgctt gaagatcctc
    15781 aggcctccat cgtacgtgtg atgccgaatg tcaatgtcag cgtaggagca ggcgtttctg
    15841 cgatttgcaa aaatgaagct gccacggagg aacagcttca gcaagctacg atgatttttg
    15901 aagcaatcgg cagcgtctat cctttagcag aatcagattt cagtacattc attggccttg
    15961 ctggcagctc acccgcattc gtttacatgc tgatcgatgc gatgggacgg actggtgtac
    16021 tgaatggttt gtccaaacag acagccactg agattgctgc aaaagcaatt atgggttctt
    16081 gtcaaaaatt cctttcaagt gataaaaatc catgggaact tgtagaccaa gtttcttctc
    16141 ctggcggtac aactgttgca ggtgtagttg ccttagaaga agcaggattc atcccagcaa
    16201 tcatcaaagg aatcaatacg acgatcgaga aagatcttga gatgttgaat aaaaaataat
    16261 gatagcaatg ttttttcgtg ccttacaaaa aaagaagagc tgtggctttt gccgcggctc
    16321 ttcttttgta ttttttatta tttagcataa tcagttgcac gagtttcccg aataacgatt
    16381 actttgatgt gtccaggata atccagttct tcttcgattc gtttacgaat atcacgtact
    16441 aaacgaacag cgtctaaatc cgagatttct tctggcttga ccattacccg aacttcgcgt
    16501 ccagcttgaa ctgcgtaact tgattctaca ccggcgaagc tgttcgaaat attttccaga
    16561 cttcttaaac gacggatgta gttttctaat gattcacttc gcgcaccagg tcttgctgct
    16621 gagagcgcat ctgctgcagc tacaaggaca gagataacag aagtagcttc cacatctcca
    16681 tgatgagaag cgatcgcgtt gattactact gggttttctt tgtacttggc agctaattcc
    16741 gcaccgatct caacgtgaga tccttcaatc tcatggtcaa gtgctttccc aatatcatgg
    16801 agcaacccgg cacgttttgc taattggata tcttcgccaa gctctgctgc taagatacca
    16861 gctaattttg caacctcgac cgaatgcttc aagacgtttt gtccataact agttctgaat
    16921 cgcagacgtc cgatgatctt gattagatct ggatgaagtg tatgagcacc gacttcaaac
    16981 gctgcctctt ccccgtattc gcgaatacgt tcatccattt ctttacgaga tttctcgacc
    17041 atttcttcga tacgcgctgg atggattcgt ccatcttgta tcagtttttc caaggtcatc
    17101 cgtgcgattt ctcttcggat tggatcgaat ccggaaagaa caactgcttc cggtgtatca
    17161 tcgatgatta aatcgatacc agtcagcgtc tcaagcgttc gaatattacg accttctcgt
    17221 ccaatgatac gacctttcat ttcatcattc ggaagggtaa cgactgaaac agtcgtttct
    17281 gaaacttgat ctgctgcgca gcgttgaatc gctaatgata ataagttttt cgctttgcga
    17341 tctgcttctt ctttggcacg ctgttcagat tcttttacca ttagagttaa ctcatgattc
    17401 agctcttctt cagtcgattt catgatgaca tctcgtgcgt cctcttttga taaaccagca
    17461 attttttcta gttctttttg ttgatcttca atcatttttt caacgtcttt ttctcgctct
    17521 tcaattaatt gctgttttga actaagtgct tcttctttac tttcaagtga gttctcgcgt
    17581 ttttctaacg agtcatcttt acgattcagc gtttgttcgc gttgaatcaa acgattctct
    17641 tgagatttta attctaactt actttctctc agctcacttt caacttcaga acggtatttc
    17701 tgattttctt ccttagcttc taacaatgct tcttttttta gagtttctgc ttcttttttt
    17761 gcactatcga tgattccagc agctgatgat tgtgcaccag ctatttcttt ctcgtgacgt
    17821 gactttgcga ccataaaccc taaaccaaga ccgacaatta aaccgatgat agcgaggaga
    17881 atgttgaata ccataaaatc cacctccata ctatcttttt catttttatc atctatacag
    17941 cttctatgat aaattattct aaactcgtca atatgcatct tcgcatatat gtgtacaaaa
    18001 aacatgcaca actttattct aatgtttgta ccccgtagtg tcaactttaa ataaacaaag
    18061 aaacggcttt ctacttattc attaaacgat ggtttttaaa ataaatgaca ctagtttcat
    18121 ataggtaaac ctttaaattg agaaactttt ctattaaatt attctttgta gatgaacaga
    18181 tatttttatt ttatgtaccc actcgtataa ttaaataact cacgatttct ttattcaata
    18241 aaaaaacggc aggtcaagga gagtacctac tcttcagacc agccgttttt gtttatcata
    18301 atttttattc ttctactaaa ggcaattctt cttgtccttt ttcatcttct gggacagcga
    18361 cttcttcacc aataccataa gctgctctaa ctagagcaga aacttctgcc atcatttcag
    18421 gatgattagc catatagatt ttagcgtttt cccgtccttg accaatccga tcttctttat
    18481 aagaatacca agcaccgctt ttatcaacaa tgtctttttc tactgccatg tctagaagtt
    18541 ctccttcttg tgagatccct aaaccataca tgacatctac ttcagcgatt ttgaaaggag
    18601 gtgctacttt gttttttacg actttgatct ttgtacggtt accaacaata tctgtacctt
    18661 gtttcaattg ttctgcacga cgtacttcca aacggatcgt tgcgtagaat ttcaatgcgc
    18721 gtcctccagg agtgatttct ggattcccaa acatcacgcc tactttttca cggatttggt
    18781 tgatgaaaat agcgattgtt tttgttttgt tgatcgaacc agagagttta cgcaatgctt
    18841 gagacatcaa acgtgcttgt aacccgacat gtgagtcacc catttcgccg tcgatttctg
    18901 ctcgtggaac taaagcagca actgaatcga ctactacgat atctacagcc ccacttgata
    18961 ctaaagcatc agcgatctct agaccttgtt ctcctgtgtc aggctgtgaa agaagtagtt
    19021 catcgatatt cacacctaat ttttgtgcat attgcggatc taacgcatgc tcagcatcaa
    19081 tgaaagcggc cgttccgcca tttttttgta cttctgcaat agcgtgtagt gcaactgttg
    19141 ttttacctga actttcaggt ccatatactt cgatgatacg tccacggggg taaccgccga
    19201 cacctaaagc gacatctaac gcaagagagc cacttggaat tgtagagatt tgttggtcga
    19261 ttttttcgcc caatttcata atagagcctt taccatagct cttttcaatt tttttcagtg
    19321 cagcatctaa ggctgcttta cgatcatctg ccaatacgat aatcctcctt atatttacaa
    19381 atcagagcaa catttcatta tccttatcat atctttttta gtgaaaaaaa gcaagaaaaa
    19441 accgaacaaa tattcgcatt tatcattttc ttaaaagctg ttttctcaaa agatcaaatc
    19501 cttgcataac cgcattatat ctgatagcag cacgatctct ggcaaagtga tatttttccg
    19561 aaaccacgcc gtctttagat gaaatagcga tccatactgt tcctgcagat tgaccttcta
    19621 acgtgtccgg tccagccact ccggtgaaag ctacactgta atctgttctt gctatctcac
    19681 gtgcttgaat ggccatctgc tccacacatt ctttgctgac tgttccatat tctgctaata
    19741 gctccggatc aatctccaga aaaccagctt ttgtttggag cgagtaggta acgaatccgc
    19801 ctggaaatac ttcagataca ccagcaatgt cgcctaatgc ggcttggaag gcgccggctg
    19861 tcaaactttc cgctgctgtt acagtctgct tgttttcttt cagtagttcc actacgactt
    19921 ttgctagcga attatcatcg ccgtatccat aaaaatattc ccctactcgt tcttggattt
    19981 tttcttctaa tgctaaaaga gcttgattcc ctgcctgaac atcatttgtt ttcactgtca
    20041 gtcgtaatgt cacttcattt ggtttggcat atggtgcgat cgttggattg atctgtgtct
    20101 caatcagatc ttttagctca gtgaccagtc gcgattcacc aatcccataa aagcgcaaaa
    20161 ctttagaaat tagtttttct tcagaaggaa aacgttcctc tagtaaagga cgtacttgtt
    20221 ccacaaacat tggtttcaac tcattaggcg gaccgggaag aaggatatac gcatgtgtat
    20281 ctgtttgata aaaagtccct aaagcaagcc ctgtacgatt tggtagagga accccgcctt
    20341 cgataatctg ggactgttgc agattgtttt tggtcatttt tcgatgggtt gtttcaaaat
    20401 atgccaataa ttttttgtat ccttccgtat tttgtatgag agacttaccg aggtgagccg
    20461 cagttgcttc ttttgtcagg tcatcttctg tcggtcctaa tccgccacat aagagtatga
    20521 gttcacttct tgtttcagct agagcaatca actcttctaa acgctgctga ttatctccta
    20581 caactgtttg ataataaact tcgataccta gatcagctag ctgttctgac aagaaagtgg
    20641 cattcgtatt cacgacttgt cctagtaaaa gttctgttcc gacagctatt atttctgctt
    20701 tcattacttc ccgctccctt atatagtata cgctgtattt ttatattttt ttatttaaaa
    20761 agagggcaag gagctgtgac aaaaatcttg tcacagctcc ttgttccaaa taaacagtgt
    20821 tctcctgcca aaacctcggt cataagtcac aatatacata aaacatgaaa agctgttttt
    20881 tgaaattatc ccttgtgact cagagttaga cggcaggctc acaacctctc cactaaacga
    20941 tacttacatt gatcctttga acacaccgct gtttttgatg aagtaatcca cacctgaata
    21001 gatagtaaag atcagacaag cataaagcat gatttgatct actggaatac cgatcaggct
    21061 gaatgggata ttattgataa acagcaagat aatagcaacc atttgtgtag ccgtcttgac
    21121 ttttcccggc caagctgcag ccatgacttc tccatgttcg acaagtagta aacgcaagcc
    21181 tgtgacggct aattcacgac agacaatgat cgctactacc caaccagggg cctttccttg
    21241 gtcaaccaac atgataaaag cagtcataac tagcatttta tctgccaacg ggtccgcaaa
    21301 cttgccaaaa ttagtgacaa ggcctcgcgc acgggcaatt tttccatcta accagtctgt
    21361 gatactagct aaagcaaaaa taactgcacc tactagctgt gtgacagcca gtgtggtgtc
    21421 tcctacgtta aattgtcccc aatctaaagg taaacctaca accaaaatga aaatcgggat
    21481 catacaaatt ctaagtacag ttaatttatt tggtaaattc acactatcga ctcctttctt
    21541 ccctattcta cgtgactatc agcgaagttt ccaccgatat tatttacttt tccaaatgaa
    21601 tttattcaaa ggagtatttt tattgaaatt gatctttttg aattaacgaa gaaggaccgc
    21661 gacacagatt tgtcacgatc cttctttttt atacctacaa gtaaacagat gcgtaaacta
    21721 atttatacga tcattctgcg tattgaagag taaggttcac attttttgga ctctgattgt
    21781 tttcccctgg attaactggt acggattctc cattcgcttt gatcgttgca ttgcttgctg
    21841 caccaatcgt gatggtcgca tttgttgctg tttccggtaa cacggtactc tgtgtttcat
    21901 ttgctgccag tgtcccttga taaacatagg cattgtctac tagcacacct aaccatacac
    21961 gattgacagc agtaaattca agggttacag gcttggtagc gtctgtgata tttactgcga
    22021 tggcactgcc agaatcttct cctgtagcta ttgccatttt cttttcttca cttgattttg
    22081 ttgttgattc tactgtagaa gactctttgg tctgcgtgct ttgctctgag gaagaggact
    22141 cctcgactga tccttctact ttaagcgaag aagctgtgtc tccgattatt ggatcagctt
    22201 gacgatcttg ccaagtcata tagcccacga caacgacaat cgccaaagca accaatccta
    22261 ataaaatgac aggaagactt gtccaaaagc gacttggatg cgattcttcc tgatgcattg
    22321 cttttctaga agtacttact gtttcaggct gcggacgttc agggaccgat cctgtcaatt
    22381 tgcttttccc atcaaaaaca tcgactaaat ggtctccatc ttctcctaca gcttcagcgt
    22441 attgccgaat aaatgcccgc acgtaaaatt taccaggcaa ttggtcaaaa tcatcattgt
    22501 cgattgcttc caaataacgt ttttgaattt ttgtaatctg ctgtaattca tctaaagata
    22561 tttttttatt caggcgtgct tgccgtaatt tttctccgat ggtttcaaaa gccactcgtt
    22621 catcttctcc agtctgtttg attctccgaa gcatctgctg ttgcaacgaa agacgttatg
    22681 tttgggtgct gtgacaaaag tcatgtcaca gctccttttt tccgaataaa cattgttctc
    22741 ctgccaactc ctcggtcaca agtcacaata tccaataaat ataagaagct gttttttgaa
    22801 cttgttcctt gtgactcgga gttaaacggc aggctcacga cctctttctt aaacggtgtt
    22861 caatcagctg ttcctcggta ttagctcaaa aaccggcaaa atataaggag atatttttcc
    22921 gtatgtttct ctaatactca ggtcaaaacg ctgatttcac aacctcttcc ttaaacggtg
    22981 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacatta agaagctgtt
    23041 tttacttggc tgttcttatt acttgatgca gggcagcttt ttcacaacct cttggtacac
    23101 ggtgttccag aagtagcttc ttcggcaata agccgaaata tcacaaaaat ttgagaagca
    23161 attttcgtaa attccttctt atttcttgaa gctgaccact tctgtcacaa cctctttgat
    23221 tacttcgttt gattttattt taatataagt tgattaaaag agagcatgat ttgttttatt
    23281 ttctcactaa tttttccaac acaactaaga ataccataaa agctgatttt ggaggaggtt
    23341 cctactacaa gtctaaaacg aaatttaaga cttttcctca taaatactgg tttattttgg
    23401 tctcatgtaa aactcgctga aggcctcttc acttataaat gcttccccag ctgccagtac
    23461 gtctttcatt tggatcgaat cgatgatttc aggaagatca aataaagttc gatcgccaaa
    23521 taaactttgc gtaaattgat tggcaatata ttcgatcgaa tttaatgatt ggaaatattg
    23581 tccaagcatt ttcttcttca gcaaatcgag atttgtttct gacacttccg gatcatcagc
    23641 gaatccaaga atgatttctt tgactttttc tgctgctttc tctggttcgt ccgtatctcc
    23701 gctgaagtcc gcaaagtgaa attcacgatc caagctgaat tcaaaaccaa agctgtcatc
    23761 gataattcct tgattgtaca tcgctagata gtttcgagaa gtattgccta aaatcatttg
    23821 gaacaacaga ttgattgctg ttttatagcg taacagttct gttccttctt gcggcaatgt
    23881 gtctaatcct ttaataccaa gtacaaattt atctcgtgta atggctgctt ccaatgcact
    23941 ttgtttgatg atttcttttg tgttttcagg gaaataacgt acaatttctt gctttggagg
    24001 gaaatttttt gcttcttggt tttcccgaat aagtttcatc aatttctcag gctccatctt
    24061 accaactaca aataaaacca tattgcttgg ctgataaaac gtccgatagc acgtatacaa
    24121 gtcttgagct gtgattttgt cgatactttc aaccgtgccc gcaatatcga tatgcaatgg
    24181 gtgtgtagga tacaagttat ttagtatgcc aaaaaacatc cgccagttag ggtcgtcttc
    24241 atacatttgg atttcctgac cgatgattcc tttttccttg tttacagttt cttctgtgaa
    24301 gtaaggtgct tgtacaaaat cgatcagagt cgtcagattc ttttctacct gatccgtcgt
    24361 agaaaacaga tagctggttt tcgtaaaact tgtgaaagca ttggcggaag ctccttgttt
    24421 cccaaataat tgaaagacat caccatcttc tttttcaaac aacttatgtt ctaaaaaatg
    24481 ggcaattcca tctggaactt tcaccttttc tttttcacca tagggaataa attcgttatc
    24541 gatcgaacca taattcgtac tgaacaaacc atatgtcttg tgatagtcat ttttaggcaa
    24601 caaatacacg gtcaaaccgt ttggcagtac ttcatgataa agtgtttcat tgatttgctc
    24661 atattctgtt ttattcattt gcatttcctc ctgctaaaaa gaagattgcc tgcaattcga
    24721 tttgctcagc tacttgttgt atctctttga tcgttacgct ctccatacgt ttcaaccatt
    24781 cttcatcaga taattttgtt tccggcagcc agctgtccaa aaaagaagct tcgattgccg
    24841 cttgcggaga gtctagagaa agcagatatt ggtttctcag cattgctttt gtctgagaca
    24901 gttccaactc tgttatttca ccatttcgca aactttctaa ttgctcgtga atcagatgaa
    24961 gtacttgatt tcggttcttt tcatcgatac cggtttggac actcatgaat cctcggaacg
    25021 tatccacgct actagaggca taataagcta gactttcttt ctctctgaca ttcatgaaaa
    25081 gtttagagtg aggaaaaccg ccaaataaac cgttaaagac cattagcgca aaacgttctg
    25141 gttcatcgta atacacattt gtctgataag ctaggttcag ctttgcttga acgattggct
    25201 cacgtacttg tcgttccttc acgatattca cttgaggttg ggtataaaac agatctggat
    25261 aaactgtttc ccgcgactca aatggtaatt gcccaactgc ttcagctgct ttgtccggat
    25321 caacatcgcc gacaacaaaa atgtcgattt gatcatttgc catcatttct tgatagtagg
    25381 acgctagcga actagcagtg atcttgtcca aatcttcgac tacgcccaac cctgggatct
    25441 tttgttccgg gctgttttca aaataaagtt cttgcaaggc ataggaagca aaagtttgtt
    25501 tatcttcctt caaactttcc aaatatagac gcagattgtt cttttccaag tcaaacgtca
    25561 actgatcaaa ctgatgattt ttaatatttg gataaaataa aacctctttt aaaaaatcta
    25621 ccgcttgaga aaaaaggttt ggatcattga catattcacc attcacaaaa ctgatccctg
    25681 cgtttagcca atgtaaattt cctttttttc taactgataa tccaaagctt gcgccataaa
    25741 gctctgcaag ttgcgcactt aactttgtct gatccggata attcaaacta tttgtttcca
    25801 acatgctgct gagaagtgaa cgtttcgtga tgacttcttg ttgcagacgc gcagtaaaac
    25861 ggataaaaat ccggatcgtt ttgtattgtt ttgttggtaa gacatgaaga ttcacgcctt
    25921 ctgccaattg atacaccata tttatatgct ccttttcaca gttgattgcc cgcttactct
    25981 tttaatgggt caacctgcct tttttactta ttcctctgct tgaaatttat aagttcaggc
    26041 aattcgccgt tttttctaaa tgatgttaca ctttatagta tagcatagat gttttttatc
    26101 aaaagaaaca gacggctaaa agcgtatatt gtttttttat tttttatttt tcgatatact
    26161 aaagacaaat aaaagaaggg agggtcattc atgatcaaag aattcaaaga gttcatcatg
    26221 cgtggagatg tcttggatct tgctgtcggc gttgttattg gtagtgcgtt tacaagcatc
    26281 gtaaaccaag tggtgcaagg cttgatcaca ccactaatag gttggtttgt cgcaatgatc
    26341 acaggtactt ctgatttaga aggagcactt tcaattcttg actggtcgcc gacaaaaggc
    26401 gtcacatttg cgtttggtaa cgttattagt gctatcatta catttctgat cactggtttt
    26461 gtcttattct tagttgtcaa agcggcaaac cgtgcgaaga atttacgctc caaagaagag
    26521 caagtggaag tggaagaaac tcctactgca gaagattatc ttagtgacat acgcgatctt
    26581 cttgccaaac aagtggcaga agacaataca catccagtag agcaaacaaa tctttccgat
    26641 acttctaaat aataaagaat ctaaaaaaaa gaaagccgat tttcagtgtc ggctttcttt
    26701 ttttagattc ttaacttgct acttgttcct ttttcatgtc gatatgtgga atatcatctt
    26761 ccaaatacac atctgagatt gccttgaatc caaacgactc ataaaaagct tgtaggtatt
    26821 cttgtgcgcc gatcacgatt ggtttttctg gaaaattttt ctggatcatg ttaatcgttt
    26881 cttgaacaat ctttcttcct aaaccatctt tacggttgtc ctgatgaaca aggacacgtc
    26941 caaaatggat actctccgct tcttcatata ctcgcgtgta ggcaaggatc ttcccatcag
    27001 tatcttgaaa aaacgtatgc caagcttgtc catcaatgtc atcaacttct tgataaggac
    27061 actgttgttc cacaacaaaa actgcgattc gttctttgac gatcgcgtaa aactctgctg
    27121 ttgacaattc ttcaaatttc tttacctgat attccactaa gcaaacgccc cctgcttttt
    27181 tattcttagc ataccgattc gcacacaaaa aagcaaacga accttacgaa tc
//
LOCUS       DAMEEU010000036        26174 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.037, whole genome shotgun sequence.
ACCESSION   DAMEEU010000036 DAMEEU010000000
VERSION     DAMEEU010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26174)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26174)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26174
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.037"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            133..3660
                     /locus_tag="PB779_001511"
     CDS             133..3660
                     /locus_tag="PB779_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HDE0739039.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
     gene            3657..7379
                     /gene="addA"
                     /locus_tag="PB779_001512"
     CDS             3657..7379
                     /gene="addA"
                     /locus_tag="PB779_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HDE0739040.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSLLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            7448..7789
                     /locus_tag="PB779_001513"
     CDS             7448..7789
                     /locus_tag="PB779_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0739041.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            8098..9141
                     /gene="pheS"
                     /locus_tag="PB779_001514"
     CDS             8098..9141
                     /gene="pheS"
                     /locus_tag="PB779_001514"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HDE0739042.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            9146..11566
                     /locus_tag="PB779_001515"
     CDS             9146..11566
                     /locus_tag="PB779_001515"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HDE0739043.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="PB779_001516"
     CDS             complement(11736..12746)
                     /gene="trpS"
                     /locus_tag="PB779_001516"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HDE0739044.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            13000..13737
                     /locus_tag="PB779_001517"
     CDS             13000..13737
                     /locus_tag="PB779_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDE0739045.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            13751..14566
                     /locus_tag="PB779_001518"
     CDS             13751..14566
                     /locus_tag="PB779_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HDE0739046.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            14579..15226
                     /locus_tag="PB779_001519"
     CDS             14579..15226
                     /locus_tag="PB779_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDE0739047.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            15242..15898
                     /locus_tag="PB779_001520"
     CDS             15242..15898
                     /locus_tag="PB779_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDE0739048.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            16060..16881
                     /gene="racE"
                     /locus_tag="PB779_001521"
     CDS             16060..16881
                     /gene="racE"
                     /locus_tag="PB779_001521"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HDE0739049.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            16884..18239
                     /gene="rph"
                     /locus_tag="PB779_001522"
     CDS             16884..18239
                     /gene="rph"
                     /locus_tag="PB779_001522"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HDE0739050.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            18240..18758
                     /locus_tag="PB779_001523"
     CDS             18240..18758
                     /locus_tag="PB779_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDE0739051.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            18865..19365
                     /locus_tag="PB779_001524"
     CDS             18865..19365
                     /locus_tag="PB779_001524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HDE0739052.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(19645..20565)
                     /locus_tag="PB779_001525"
     CDS             complement(19645..20565)
                     /locus_tag="PB779_001525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HDE0739053.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            20730..21743
                     /locus_tag="PB779_001526"
     CDS             20730..21743
                     /locus_tag="PB779_001526"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HDE0739054.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="PB779_001527"
     CDS             complement(21853..22608)
                     /gene="fabI"
                     /locus_tag="PB779_001527"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HDE0739055.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            22828..23268
                     /gene="fabZ"
                     /locus_tag="PB779_001528"
     CDS             22828..23268
                     /gene="fabZ"
                     /locus_tag="PB779_001528"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HDE0739056.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            complement(23383..24144)
                     /locus_tag="PB779_001529"
     CDS             complement(23383..24144)
                     /locus_tag="PB779_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HDE0739057.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            24333..25427
                     /locus_tag="PB779_001530"
     CDS             24333..25427
                     /locus_tag="PB779_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDE0739058.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            complement(25513..>26174)
                     /locus_tag="PB779_001531"
     CDS             complement(25513..>26174)
                     /locus_tag="PB779_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HDE0739059.1"
                     /translation="VSCGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQR
                     SIHDRPDNYPDFNSEFGHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIE
                     TALNQWFSRFPKNFFKSITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSN
                     GILRRNGLPKSMDFRKVNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSL
                     I"
BASE COUNT         8652 a         4537 c         5510 g         7475 t
ORIGIN      
        1 tttttgcgta tacttaaaaa agtagaaata tcagaacctt aaaaggatat aatttgaaga
       61 atatagaaca aatgttcagt attttttgat ataataaagg agcaccgtat catgtgttga
      121 aggaggaaaa gcatgtcttt acaatttatt cttggaaacg ggaaaaaaga tcaccgtcaa
      181 gtcttgatcg acgaagcatc cgcttggctc gaccaggatg caagtaacca agtatttttc
      241 cttgttccca actacagcaa attcgaacag gaacaagaaa ttttagcgga gatgcgaaga
      301 agaagcggaa aaaaaacttt cagcacaaca aacgttcaag tatttagttt ttatcgtctg
      361 gcttggtatt tgctgcaaca gacaactctt cttacaggaa atgaattatc agaatcagga
      421 tctgcaatga tcttgcgaca gattttagaa aaaaatgagg aagaattaac aatctttcgc
      481 ggagaaatca ataaaagagg gtttattcgt caattacaag aactctacag tgaattgcgt
      541 acaggaaata ttcaaccaga agacctgatg cttttatttg gtgattcacc taatgcagaa
      601 gaccagcaac ttaaaatgaa agacttgaag ctgatttttt cagcttatga cagcgaattg
      661 actcaacgtg cactaacaaa tgaagatgca ctatctatac tagcaaatta tatgcagaca
      721 caagatttca acaacgtcaa atttattgtc agtggttttt ctcgaatcaa tggtcaagag
      781 tatcaattac tgcaggcaat gatggaaaag gggcaattgg ttgtcgattt attgctggat
      841 cgtccttata cagcggatct tccagaagta cttacgctct ttcatgagac tggaaagctt
      901 tatttccgtc tttttcaaag tgcaagagaa cggaaagtcc ctatattagt ggaccgattt
      961 gcaccagagc agactcgtcc gacagagctt caactgctgc aaacaatgtg ggaagagaca
     1021 tctagccaaa agaaagcggc agtacacaaa atagggggac aagagcatct ccatttgtgg
     1081 gaagctgaaa atccaactga agaagtccga caattagctg ttgaaatcag acgactagtc
     1141 agtgaagaaa actaccgtta tcgtgatatc caagtgctga caaaaaatat gtctttatat
     1201 ggaaatatcc ttcggccgat ctttcaagaa atggcaattc ctttttatat cgatgaagaa
     1261 caaatgatgg aaaatcatcc gctgatcgaa tggatcaaca gtctgttcgc tcttgaccgc
     1321 tattcttatc ggctaagtga tattatgcgt tttttcaaaa ctgaattatt tctgtcgacg
     1381 gaagcagaaa ccgaacttga tgaatggaaa caagagcgag atgaattcag gaaaaaactg
     1441 gacatcactg aaaatgtagc acttgcttac aattatcaag gaacttattg gactcgtgaa
     1501 aaagactggc agtttgtggc gtatgatttt gaagcagaac agattgaaga cgtacagtat
     1561 ttggaagaac agtcaaatac gattagacga ttatttcaga aagctgtacc agtatttttg
     1621 aaaaaaataa agaaaagcaa aacaggacaa gaggccgcaa atgtttttta tcaatttttg
     1681 atccaaagtg gcgtacagca acaattattg ttttggcgta atcaggaagt agacagagga
     1741 aacttagaag cggcaagaaa ccatgagcag acatggggag cgctgattga tctgttggat
     1801 gaatatgtag taatttatgg tgaatcggct tttgactggt cactgttcca agaaatcatt
     1861 acaagtggtc tagaaaatct aagttatggt aaaatcccta ccgcaatcga ccaagtgcga
     1921 atcaatcgtt tggaattagt tcgaccaaat caagctgccg tcacttttgc attagggttg
     1981 aatgatcaag tgtttccaga ccgaaaagag acaaaaggat tgttgtccag tgaagaacga
     2041 gaagtattaa atcaggcctt gccagatgga cagtttttat tcgacccatc aaaggaaagt
     2101 atctcttttg agcctttcca agcctatctt gtttttcttt ccggaacaga tcgattatat
     2161 cttagttatg cacaaagcta tgacacagat ggttcgctga agatgtctcc ttatttgcgt
     2221 agaatcacag aatatttatc tgttcccgtc gagagaaaag agcatttgac gatcgaaagc
     2281 gaccctaatt gttatgtagg gacttacaga agcggaatca atacagtcaa taggatttat
     2341 cgattagctt tagatgaaaa aaaacctgta ccaaagcact ggcaaaagct caaagaatta
     2401 gtactgaatt cgtcatggcg aaattttgct ttacagattt ttgaaagtca ggaacattta
     2461 aatgttcctg tttcgatgcc agaaaaaatg gcggaagagc tttatggaaa agagatttat
     2521 acttcaattt cacgtatgga gaatttttat aattgtgaat acaaatactt catgcaattt
     2581 ggtttgaaat tgaaagaacg aactgtttat ggtctaactc cagcagcaac tggtgatttt
     2641 tatcatgaat cattggatcg tttcttcaag ctactgtttt caaaccaatt atccttagtg
     2701 aatatgtccg atgcgcagcg tagagacttt actgaaaaag tgctgcagga agtattcgga
     2761 gaacttcggt ttgagatatt ggatagttct gcaagaatga actatatccg ctaccagtta
     2821 ggacagacga ttcaaaaagt gacatgggct ttgcaaaaac agagcaaaaa tacaggcatg
     2881 catcctcttc agacagagat tctatttggt cagattgctg gagcaaaagg tatcacaggt
     2941 ctggaattac cgttgagtaa tggtggaaaa ctccatgttc gagggaaaat cgatcgaatc
     3001 gatgtagctt ctgaacaaga agatacttgg ctaagcgtcg ttgattacaa atctagcgga
     3061 cgttcattcg atgtcacaga agcttattat ggcatggcta tgcaattatt gacgtatctg
     3121 gacgtagcat tgatggatgc ggtacgtttg actggaaagg cggctgttaa accagcagga
     3181 tcatattatt tacatgttca taatcctgta ttgacggaga cagatgatgt agagaagaat
     3241 acattgaaaa aatttagtta tgatggcgtt tttgtcgatg atcccgctct tttagaagta
     3301 ctagatcatt cactggaagc aaaagaacaa tcactgatct atccagtgaa aaaaaatgcg
     3361 aaagatgaat accaaaaagg tagtttcagt aaagacaaat ttttcacgga agaagaactg
     3421 caactattca tggcgcataa tcgggaaaat atgcggttag ctggagatgc gattacttcc
     3481 ggagaaatca aactaaatcc agcttataaa gataaacagc ggattgcctg cgaattttgt
     3541 ccattcagaa gcatctgtac gtttgatgtg atgctgaaag aaaataatta ccaccgtctg
     3601 gagaaaatag ataaggaaga agcactgcgt agaatattga aaaggagtga agaagagtga
     3661 atcaaattcc tttaaaaccg caaaatgaac gattcacaga tgatcagtgg caagcgattt
     3721 ttgatcaagg agataatcta ttagtctctg cgtctgccgg atcaggtaaa actacagtgc
     3781 ttgttcgaag agtgattgaa aaactaaaaa tgggttttga tatcgatgaa ttattgattg
     3841 tgacatttac tgaagctgcc gcaagagaaa tgaaagaaag aattcaagag gcattacaag
     3901 aatccgtcaa tagcgaaagt gaccctgtac gtagacagca ttttactaag cagttagttt
     3961 tattgcccac agcgaatatc tcaaccttac atgctttttg cctgacagtt attcgacgtt
     4021 attattactt aattgatatt gatccagtct ttcgcatgtt aacagatgaa acagaaacga
     4081 tcttgatgaa ggaggatgtg tgggacgagc tgagagaagc actttatgca gaaaatgatg
     4141 aacgattttt ccaattaaca atgaattttt ctaatgatcg ttcagatgac ggcttgacga
     4201 atctggtgtt ttctctttat gagtttgccc gtgccaaccc tgacccccaa aaatggctag
     4261 aacagttaag cgataattat cgtttgcctg aggggctagc gaaatctcga ttatatcaaa
     4321 aacaaatccg tcctttagtt ttggcagata tataccaatg tgtacagtta tatgaacaga
     4381 tgactcagtt agcacaaggt gaaggattag aaaaaatgca tgagcaagta gctggagaac
     4441 aacagcagat caagaatatc tatgaagcgt tctcgcaaga tcggttagaa gaagcttatg
     4501 ctggtttgga acaactaact ttttcaactt ttaagagcag tcggaaagca gaattgaaag
     4561 aaatttccaa tgaagtcaag ggcatgaggg ataaagcaaa aaaactgatt cagcagataa
     4621 gtaaaagtta ttttcctgtt tccccaagcc aaatggaaga attaacggac aaagcactac
     4681 cgttagtcga agaaatgaca aaagtcacgc aaagcttcat ggacggtttc agtatgcgta
     4741 aacgggaaaa aggtgtgctg gatttcaatg atctggaaca tttagcgttg cagattctca
     4801 cagaaaaaac gaaagatgta tggctgccaa gtgaagcttc aaaacattat cgaaaaaaat
     4861 tcaaagaagt aatggtagat gaatatcaag acgtgaacca attacaagaa gccattttat
     4921 actggctaag agaacccgat gatacaaaag gaaatatgtt catggttggg gatgtcaaac
     4981 aatccatcta ttctttccgt ttagcagatc ctagtttatt tatcgggaaa tacgagaatt
     5041 tctcaaagaa agaaggcgga cgtcgaatcg ttttggctga gaacttccgc tctagaaaag
     5101 aagtcctttc ttttacgaat cttatttttg aacaactaat ggatccagca gtgggtcaaa
     5161 tcaattatga cgaagcagcc aaactgatcc aaggattttc agactttcca gagaatgaac
     5221 agtttgagcc ggaaatcatg atctatgaaa aagaacagga agaatcagag attgagattc
     5281 cgacggatga tatactggaa gacaaaacag aaggcgaact ttttatgaca ggactaaaaa
     5341 ttcgtcaatt aattgattcc tcctttatga tttatgataa aaaatcaaaa aaaagtcgtc
     5401 cgatagagta caaagacatt gttctcttga cacctacaaa gaagaacaac ttaacgattt
     5461 tagagatttt caaaacattg gatattccat tagagatgaa tgatgctcaa aactattttc
     5521 aagcgacaga aattcgcacg atgatctcgc tgctacaatt aatcgataat ccctatcaag
     5581 atattccgct tgcggctgta ttgcgctcac cgatcgtggg tctgattgaa ccagaattag
     5641 ccagcattcg attagctaac cgtgcacata cttactatga tgctgtgctt gcttatcaag
     5701 catcaaacga agatgaatta gcagctaagc tggaacattt tggcaagcaa ctagagcatt
     5761 ggcgagaact tgctcgccgt tcttcgatca ctgacttgtt atgggatatc tattatgaga
     5821 cgggatatct agagtatgtg gtcggtctgc cagcaggggc acagagacaa gccaatcttt
     5881 atgcattggt tgatcgtgcc aaagcttacg agcaaagttc tttcagagga ttataccagt
     5941 tcgtgcgttt cattgaaaaa atgcaagaaa aagataaaga cttagcagaa ccagtcattt
     6001 caatagaaga taatgctgtt cgcgttatga cgatccatgc aagtaaaggc ttggaattcc
     6061 cagttgtatt tttgttagat atgacaaagg agttcaactt acaagacttg cgcaatcggt
     6121 atgcttttga agaaaaactt ggagcaggaa ttcgctatat ggatcctgaa acacgagtgt
     6181 tatatgatac gttaccgttt caagccatca aattggcaaa gcaaaacaaa ttgttgtcgg
     6241 aagaaatgcg taaattgtat gtaggattga ctcgggcaga acaaaagctt ttcattgtcg
     6301 gttcctataa aaataaagag caaatgatcc aaacgtggtc tgaagcagct gatcatgagg
     6361 agttagtttt tgatcctgcg ctacgtttga agggcagaag cagcttgatg aattggattg
     6421 gttacggatt gatccgtcat cctgaaatgc agaaatactt agaggaagaa atttcgactt
     6481 ctcttcttca acattcaaat gcacagtttt ctatttcatg gatgaatcag caatcgatca
     6541 ttgaacaaag acagttgctt gctgaaaaag aactggttaa cttagatcag cagatgaaag
     6601 aagatgaaac tttattagca gattcgttac aaaaacgtct ggcatatgaa tatccttatc
     6661 aagcttcttc acaaaccaca agttatcaat ctgtatctga aatcaaacga ttattcgaag
     6721 atccagatga tacacaagaa tcacgtttga ctctggaaag cagtcagaac aaagcagcat
     6781 cccgtcaatt tcgttatacg caagaacaac tagcagaacc aaaatttttg caaaaagatc
     6841 ggcaagtgtc agcagctgct gttggaactg ctacgcatgc tttgttacaa ttactgccat
     6901 tagagatgcc aactacagag agtatccatc aaaaattaca ggaattggta aggaaacggt
     6961 tagtagacga aaaagtcgcg aaaaaagtag atgtttcttc tattatatgg ttctttcaaa
     7021 cagaacttgg tcaacagctg attgccaaca aagaaaacgt aaaacgagaa caaccttttt
     7081 ccatgctgct tcctgctgac gaagtatttc aagactatcc aaatcaagaa gatgaactat
     7141 taatccacgg aatcgtcgat ggatacctag aagaaaaaga tcatctcaat atctatgatt
     7201 ttaaaacaga ttttatttta catccggatg atccagcaga aatagatgca atcgtccaaa
     7261 aatatcaagg acagctaaga ctttaccaac aagcaatgtc agaagctttg aataagccag
     7321 tagaaaatgt tttcctaatt ttgcttcgag tgaaacaaat tataaacatt aacaaataat
     7381 tataattgag caaacttgac ttatgttttg taaggattat gctatactct gggaagaggt
     7441 gagtatgatg gagctaacac agacagaatt cgttttatgc cctaaatttg aaaaaacatt
     7501 ctctatttta ggaaaaaaat ggaacggatt gattatcgat gtactactcg aaaacggtcc
     7561 gcaacgcttt gttgagcttg cggcaaaaat cccgatggtc agtgatcgag tattagtcga
     7621 acgcttgaag gaattagaaa aagaaggaat agtcactcga aactttgcct gtagcgaaaa
     7681 gagccgttca gaatatctct tgactgaaaa aggagcagac ttgcaaaaag cgatgcgtca
     7741 aatacaagtt tggagcgaaa aatggatcac agaggaagaa tgcggttgat tttgtaaaaa
     7801 aaatcttgta aactatagtc catacgaata agtaaagaac gatgacgaaa aagagtagtt
     7861 tggctaaacc agttcaggga gatctgtcgc agactgaaag cagatcctgt gtttgaaaaa
     7921 tgaagttcac tttccgagtt cgtctgataa aatcagaccg gcaattgtcg ttaacgaagt
     7981 aagagtgcgg tgtaagtcat ttatccgcaa attaggatgg taacgcgaag acctcgttcc
     8041 ttaacaggaa tgaggtcttt ttgttttgta tttggaattt aaaggaggaa caagcacatg
     8101 tctctacaag cacaattaga gagcttgaaa gaagcaacgc tcgtcaaaat cacagcggca
     8161 caagatttaa atgaattaaa tcaaatacgt gttgaaacgt taggaaaaaa aggaccgatc
     8221 acagaagtat tacgtgggat gaaagatcta agtccagaag agcgaccaaa agtcggaagt
     8281 ttcgcaaatg agatccgaga tcttttgaca gaagagatcg agcgaaaaaa acaagtatta
     8341 gaagaagaag cgttaaatgc agctttggca aaagaaacaa tagacgtgac actacctggt
     8401 agaaaagtaa aacatggtac acgtcatatc gtgacacaaa tcatggaaga aattgaagat
     8461 atttttgtgg gtatgggcta tcagatcgta gaaggatatg aagtagaatc tgatcattac
     8521 aatttcgaac ggatgaatct gccaaaagat catccagcaa gggacatgca agatactttc
     8581 tatatttcag acgagatatt gattcggaca catacttcac cagtccaagc acggacaatg
     8641 gaaaaacatg atttctctaa gggtgctcta cgaatgatct cgccagggaa agtcttccgc
     8701 agagatacag atgatgcgac ccacagtcat cagttccatc aaattgaagg gctagttgtt
     8761 gataaaaaca tcacaatggg cgaccttaaa ggaacattag aagtcgtaat gaaaaaaatg
     8821 tttggggaag atcgtgaaat tcgtttgcgt ccaagttatt tcccatttac ggaaccatca
     8881 gtagaagtag atgtcagctg tttcaaatgt ggtggtgccg gttgtaacgt atgtaaatac
     8941 actggatgga tcgaaatttt aggagctggc atggtacacc cgaatgtgtt gaagatgtca
     9001 ggaatcgatc cagaagaata ttcaggcttt gctttcggcc ttggaccaga ccgcgtagct
     9061 atgttgcggt atggagtgaa tgatatccgt aatttctatc aaaatgactt acgtttctta
     9121 agtcagttca agggggagta agaaaatgtt agtttcatat aaatggctca atcgttatgt
     9181 agatttatcg aatgtaacac caaaagaatt agcggataag atgtctgtga caggaatcga
     9241 agtagaggga gtaacggttc cagaagaagg cttgaaaaaa atcgttgtcg gtgaagtcaa
     9301 ggaatgcgta ccacatccag attctgatca cctttctatt tgtcaagtcg atattggcga
     9361 agacgaactg tctcaaatcg tttgtggagc gcctaatgtg aaggttggaa tcaaagtgat
     9421 tgttgcactt cctaactcac gtatcgctgg taatgtaaaa atcaaaaaag gaaaaatgcg
     9481 tggccaagta tcaaatggca tgatttgctc attacaagaa attggctatt cagatagtgt
     9541 tataccgaaa gaatacgctg aaggtatcta ttatatgcca caagaagctg taaatggcga
     9601 tccagttttt ccttatttgg atatggatga ttcgattatt gaattatcta tcacaccgaa
     9661 tcgtgcggat gcattgtcaa tgcgtggcgt agcttatgaa gttggggcaa tttatcgtca
     9721 gactcctaca ttcgatgacg aaaagctggt agaatcctca cgtcctgcta gcgataaaat
     9781 tcaagtggaa gttgaagata aagaagcagt tcctgcttat caaatcagaa tcattgaagg
     9841 agtaagaatc cagccaagtc ctcaatggct gcaaaatctt ttgatgaacg aaggcattcg
     9901 tccaatcaac aatgtagtag atgtgacgaa ctatattttg cttttattcg gacaaccact
     9961 acatgcattt gactacgaca aattgaaatc aaaagagatc tttgtccgcc gtgcaaaaga
    10021 aaatgaaaca ttagtaacac tagatggaga atctcgggaa ttgacaactg acaatctcgt
    10081 cattactaac ggcaaagaac cagttgcttt agctggtgtc atgggagggt tagactcaga
    10141 gatcacgaat gaaacaacaa cagttgcact agaatctgct ttatttgatc caatttcgat
    10201 tcgtcgtaca gcaaaacaat ttaatttgcg tagtgaatcc tctgcacgtt ttgaaaaagg
    10261 aatcaaccat gcgactgttg gagaagccag tgaggttgct gcagcaatga tcgtttctct
    10321 tgcgggtggg gaagttctac aaggcgcggt caaaggctca gagatcaaag cagaagacgt
    10381 atcagtgaag atttcacttg aacgcatcaa tcaatattta ggaacatctc ttgtcgttaa
    10441 agaagtaaat gagatttttg aagcacttgg atttagctat gaagaaaagg agtatgttta
    10501 ttccgtagta gtaccaccaa gacgctggga tatccaaatc gaagcagata ttatcgaaga
    10561 agttgctcgt atttatggat acgaccagtt gccatctaca cttccaagtg gagaaacggt
    10621 tgctggaagc ttgtcaaaag aacaagaaac tactcgtaaa attcgtacaa tctttgaagg
    10681 aagcggattg agcgaagcaa tcagttatgc attgacaaca gaagaaaaat caagacagtt
    10741 tgttataaat gaaagtaata ttacacgttt ggactggcca atgagcgaag aacgttctgt
    10801 attacgaatg aatttgatca gcggactatt agatgatatc agttataaca ctgcccgaaa
    10861 aaatacagag attgctttat atgaaattgg tcgggtgttc ttccaagaaa atgatccacg
    10921 tacacatctg ccgcaagaag taaaacatgc agcaatcgct atttctggta tttgggaaga
    10981 aaaagattgg cagacgaaag ctcaaaatgt agactttttc accatcaagg gtcttttaga
    11041 aaacttattt gaacaactag gcatcactga agatgtccat tatcaaacag tgacagaaat
    11101 gaaggaaatg catcctggaa gaactgctgc gatttacctt ggcgaaaaat ttattggttt
    11161 tgtcggtcaa gtgcatccaa cgattacaaa aagttatgat attccagaaa catatgttgc
    11221 tgagtttgat ttatctgcta tagtggaagc tgctcaaaaa gggatcgttt tcgaagcagt
    11281 gacaaaattc ccagcagtca gccgggacat cgctttgctt gtaaaagaaa ctgtgacaaa
    11341 tcaggaatta acagaagtta tccgttctgc tgccggaaga tttttaacag atatccaatt
    11401 atttgatgtc tatcaaggag aaaacattga aaaaggacat aaatccatgg cgtatagcct
    11461 gacattcgtc aacccagaag caacattgac agatgaagaa atcaataaag caatggaaaa
    11521 agtcgaaaaa gcgttggtag aaaacctaga ggcaagtatt cgctaagaag gaaaatatag
    11581 taagtaacga tcaagtagct tttgaagacc atacatttga aaaaaagatg tgacacaact
    11641 tcgtcacatc tctttttttg attttaaaaa aggaatagca cagagacgag ataaaaaaac
    11701 aggcctttac agcctgcttt tttagagtaa atgaattaat ggaagtaatt gattcccatt
    11761 gctgatttta cttcagaaag tgtttgtgca gctactttag cagcttcttc actaccttta
    11821 cgtaagattt ccataacagc tgaaggatct ttttccaatt cttctcggcg cgcacggatc
    11881 ggtgcaaatt cagcttccaa tacatcaatg aggtatcgtt tgatctttac atcaccaagt
    11941 ccgccgcggc ggtaatgagc tttcatttct tcaattgctt ctttatctgt tccgaataca
    12001 tccaagtagg tgaagaccat attcccttct acttgtccag gatcttgtac atggatgtgg
    12061 tttggatcag tatacatact catgactttt ttctgtaaga catcggcagg atcggagata
    12121 taaataccgt ttcctaacga tttactcatt ttgccatttc catcgattcc aggtaatcta
    12181 cccattcctt ttggtgggaa tacgcctttt ggttccacca agacttcacc atatgtatga
    12241 ttgaagcttt gtacgatttc ctgtgtctgc tctagcattg gtttttgatc ctcaccaaca
    12301 ggtacaagat tcgctttgaa tgcagtgata tctgctgctt gagaaacagg atagataaag
    12361 aatcctgtag gcacgctttc accgaatttt ttttgttcga tttctgtttt gacagtcgga
    12421 ttgcgccgaa cgcgtcctac gctgactaag ttcaaataat acatggttaa ttcagctaat
    12481 tccggaattt gtgattggat aaataaagta gattttgcag gatctaatcc cacggctaaa
    12541 tagtctaaag caacttgcaa gacatttgat gaaaccttct caggattttt agcattatct
    12601 gtcagtgctt gcatgtcagc aatcatgaca aacagttggt tgtcttcatc tgcctgcata
    12661 gccactcggg tttttagaga accgacgtaa tgccctaaat gcagcttccc agttggtcga
    12721 tctcccgtta aaataatatt tttcaaaaaa gacacctctt tacgatttgt aagtctgagc
    12781 acttaatatc ttaccgtttt tcctgaaaag aaacaacagt tcctaaggaa aaaacaagga
    12841 aagaggataa aataactaat agattagaaa tggaagaaat atttatggga gaataaacgt
    12901 tctaagaaac tttacaaatt actaaactat cagatataat gtattttatt atacatcttt
    12961 aaaagaaatc ttactaaata ataatgggag tgtaattcta tggcaatgat taaatttgat
    13021 cacgtggata aatattatgg caagttccac gcattaaaaa atatcaatct cgaattcgag
    13081 aaaggagaag ttgtcgttgt cattggtcct tctggttcag gaaagagcac gatgcttcgc
    13141 tgtatcaatg gattagagac gatctcttca ggtaagctgc tgattaatga tactgacttg
    13201 catgataaaa agacaaaact gacagaagtc cgaaaaaaca tcggcatggt tttccaacat
    13261 ttcaatttgt acccaaataa aactgttctg gaaaacatca aattagcacc aatcaaagtg
    13321 ttgaagcaag accaggcaac tgcagtcaaa aacgcggaga aatttttgaa aactgtcaat
    13381 atgttagata agaaagattc ttatccttcc atgttatccg ggggacaaca gcaacgggtg
    13441 gcaatcgcca gaggtttagc gatgaatcct gagatgctgc tgtttgatga acctacttct
    13501 gctttggatc cggaaatgat tggtgatgta ttagacgtta tgaaaaaatt ggctcatgac
    13561 ggtatgtcaa tgattgtcgt gacacatgaa atgggctttg ccaaagaagt ggcggatcgt
    13621 gttatcttca tggctgatgg agaagtattg gaagacagca gaaatgtgag agactttttc
    13681 gaaaatccaa atgaagtccg agcacagcaa tttatcagta aagttatcaa tcattgatag
    13741 gaggaaaaag atgcgcaggt taaaaaaaat acgcctgatt ttccttttag gcattgcttt
    13801 tcttgcacta gccggatgta aaggaaatgg gttggcaaat gaagatattt tagagcgaag
    13861 caaatctacc aatgaaatca tctggggtgt caagtatgat actcgattat ttggaatgat
    13921 ggatattgag agcagaactg tacaaggatt tgatgtagat attgcaaaag caatcactaa
    13981 aaagatcctt ggtgacaatg gaaaaacaga atttgttgaa gtcacttcta aaactcggat
    14041 tccattattg aaaaacggaa atatcgatgc aattattgca acgatgacga tcacagatga
    14101 acgaaaaaaa caggttgact tttcagatgt ctatttcgat gctggccaag ctttgttggt
    14161 aaagaaagga agccaaatca aaagtgtaga tgatttgaat gcttctacaa cggttctagc
    14221 agtcaaaggt tctacatcgg ctgcgaatat ccgacagcat gcaccagatg caaaaatttt
    14281 agaattagaa aactatgcag aagcatttac tgctttacaa tctggtcagg gagacgcgat
    14341 gactacggat aatgcgattt tgttagggat tgcagatgaa aatccagagt atgagttagt
    14401 tggtggaacg tttactaatg agccttacgg gattgcgatc aacaaagggc aagaaaactt
    14461 cttgaaagct gttaaccaag cgctagagga aatgcatgca gatggcacat acgataaaat
    14521 ctatcaaaaa tggtttccaa atgaaactga aggaaaagta gagtaagggg gagaggcaat
    14581 gagcgaattg atacaaactt atggaccaat ctttgtcgac gggttcaaga tcacattgtt
    14641 ttcgagtgtc ttagcacttg tgtttagttt gattatcgga acgttaatgg caatcttcca
    14701 attatcaaag aataaagtag tgagcgcctt agcaaaggca tatgtagaat tttttagaaa
    14761 cattccatta ttaatcatcg tgatgttttt ttatgttgtc gtaccgattt attggtttaa
    14821 tctagatgga ttccaagcag gtacgattgg attaacgatc tatacatctg cttttattgc
    14881 tgaaacagta cgttcaggga ttcaaaccgt accaaaaggt caaacagaag caggactatc
    14941 ttctggtttt acctattcag aaatcatgcg ttatattgtt ttaccgcaag cattcaaaat
    15001 cgttatcccg ccattaggca accaatttat caacctcgta aaaaactcat ctattttagc
    15061 aatcgtagct ggtttagatt tgatgtatca aggagacttg atcgctagtg aaacattcaa
    15121 taccttcgat acgtatatca tcgttgggtt attttactta gttatcacgc taccgttatc
    15181 ttacttaatg gtttatcttg agaaaaaatg ggcggttcgt tcatagaagg aggggaaata
    15241 catggatttt agcggcgctt tttcatggat gaatatccgt tttttattgg aaggattaaa
    15301 ggttactgtt gaagtttcat tgttttcgat catttttagt ttcttgatcg gtggtctgac
    15361 aggtgtgatt cgttttgcga atatcccttt cttttccaaa atccttggtg tagtgattga
    15421 tattatacgg aatcttccat tattattgat cattttcttc acttactttg ccttacctca
    15481 aatcggcatt cagatgaaca tcttctggtc cgctgtcgca gcattaacga tttttgagtc
    15541 agctatgttg tcggaaattt tccgagctgg actcaatgct gttccaaaag gacagatgga
    15601 agcaggatta tcaacgggac tgacttatgt agaatcgatg cgaacgatcg tgttaccgca
    15661 agcatttaaa tcaatgatcc cggcaattgt gagccaattg atttcactga tcaaagatac
    15721 ttcattagca gtaatcattt ctttacctga actttctcat caggcacgta ttatttatgg
    15781 acagaacacc aattatgtgc ttccgatgtt catcatcatg acacttatgt acttcgtggt
    15841 atgttacgcg ctttctctgc tttccggtta cttggaaaag agacggtaca gttattaata
    15901 gatgattctt ttagcggttg tggcaaacta aagtcacaac cgcttttcct ctttccattc
    15961 gaaaaaaaga gatttcgatt gttttaagca agtaagagca cttgaaaatt cacgctaaaa
    16021 agtacacaat agggaggata gaatttattg aaaaaaagga tgatacgatt gacagataat
    16081 cgccctatcg gatttattga ttcaggtgtc ggcggcttga ctgtagtaaa agaagccctg
    16141 aaacaattac cgaatgaaaa tattttattt gtaggagaca cagcacgctg cccatatggc
    16201 cctagacccg cggaacaggt aatccagtat acttgggaaa tgacggatta tctggtggag
    16261 caaggaatca agatgctggt gatcgcctgc aataccgcaa ctgcggtggc tttagaagaa
    16321 atcaaagctg ctctttctat tccagtcatc ggtgtgatcc ttcccggtac tagagcggca
    16381 gtaaaaaaaa cacaaaataa acaagttggc attatcggta cgattggtac ggtaaaaagt
    16441 caagcttatg aaaaagcact gaaagagaaa gtaccagaat tgactgtgac aagtcttgct
    16501 tgtcccaaat ttgtttcagt tgtcgaaagt aatgaatacc attcatcggt ggcgaaaaaa
    16561 attgtggcag aaacattagc tcctttaacc actaaaaaaa tcgatacatt gattttggga
    16621 tgcacccatt atccattatt acgccccatc attcaaaatg taatgggaga aaatgttcaa
    16681 ctgatcgatt ctggagcaga aacagtaggt gaagtatcta tgctgttaga ttatttcaat
    16741 ttgagcaatt caccgcaaaa tggtcggaca ttatgccagt tttatacaac tggctctgcc
    16801 aaacttttcg aggaaatagc tgaagactgg cttggaatcg gacacttaaa tgtagaacat
    16861 atcgaattgg gaggaaaata aggatgcgtc atgacgggag aaaagcccaa gagcttcgca
    16921 aactggagct tcaaacaaat gttttcaaat atccagaagg atcggtagtg atccgttttg
    16981 gtgatacaac agttatttgt tctgcaacaa tagaaaattc tgttccccct tttttgagag
    17041 aaacaggaac aggatgggtg acagcagaat atagtatgct gcctcgagca acgagtacga
    17101 gaaatcgtag agaaagcagc aaagggaaac tttctggtag aacaatggaa atccagcgtc
    17161 ttattggtcg ttccttgcgt gcagtagtag acttggaaaa attaggagaa cgtagtatca
    17221 tcgtagactg cgatgtgatc caagcggatg gcggtactag aacagcaagt atcactgggg
    17281 catttgtggc attgaaatta gccattgaaa aacttttaag agaaaaagaa ttgtcagaag
    17341 atccaataaa agaacatctt gctgcagtta gcgtaggaat cttaccagat gggacttgcg
    17401 tcacagattt ggattaccaa gaagattccg cagcacttgt agacatgaat cttgtaatga
    17461 cagaatctgg aaaattcgtg gagattcaag gaactggaga agaagcaacg tttgatggtg
    17521 aacagttgaa tgaaatgctc ttttttggaa aaaacgcgat tgaagatttg atcaaagagc
    17581 aaaaacatgc tttgctaaca gagtttgctc aaaatgatga gcggatagaa gaaacaaaaa
    17641 caatcatcat tgcgacaaga aatccaggaa aagcagaaga gtttcgaaat atgttcaaag
    17701 aagcgggata tcatgtaaaa acattacttg actatcctga attgccagat gtggaagaaa
    17761 ctggcagcac atttgaagaa aatgcccgat taaaagcaga aacgattgca caattgcttg
    17821 atcagccagt cttagcagat gattcaggtt tgaaagtgga tgctttaggc ggtatgccag
    17881 gaatctattc tgcacgtttt gcaggggaac aaaaaagtga tgcggggaat aacgccaaat
    17941 tattatatga attgacagat gtgccggatg aaaaaagaac agcacaattc cattgtacgt
    18001 tagtattcgc ggcacccaaa aaagacagcc ttgtagtaga agcggaatgg cccggtcgag
    18061 tagcccgtat accatctggc gaaaatggct ttgggtatga tcctttattt atcccagaag
    18121 gtaagaaaca aacagcagca gaattatcga gcgaagaaaa aaacaagatc agtcatcggg
    18181 ctcaagcaat gaaaaaattg agtgccgagt ggaaacaatg gctggaagga gagagataga
    18241 tgcggtattt agtagtaagt gataatcatg gagacagaga tatcctcgtt gacttagtag
    18301 atcgttatcg ttctgaagtg gatatctttt tccattgtgg tgattcggaa ttagaagctt
    18361 ctgacccatt atgggataca ttccaagtgg ttcaaggtaa ttgtgattat ggaccaggat
    18421 tcgaacagaa aaaagtgatc caaactggtc aggatacagt attcatgact cacggtcatt
    18481 tatcgaatgt ccgatttggt ttgacacagt tagcaatcga agctcgagct gcaactgccg
    18541 atatggtgtt ttttggtcat acccatcaaa taggctgtga gatggatcag aaaatcctgt
    18601 ttttgaatcc tggtagcatt tctcagccta gaggcccgat ccaaatccca tcatatgctc
    18661 ttatcgaaag tttagatgac caaatttctg ttcaatacta taaccgtgcc catcaggcag
    18721 ttgaagagtt ggccttttct ttttcgagag agcgctgaat aaaaaaactc taatttttaa
    18781 taaaaataag ctttatttta tgaattttgc atccggtttc ggtaaaatag tagtgttgaa
    18841 tgaaatagaa atggaggcca tcagatgatt ggacctatag taagagaaat gctgctggaa
    18901 aatcaggaaa cgtttttgat tcctgcagaa aatgtggcaa atgttatgta tcatcatcca
    18961 ttgtcccatg gtttacttgt gttatcgaag gtcggttatt ccaaaattcc tgtattagga
    19021 aaagatgatc actttgtagg actagtaagt ttatcagatg tggtcaataa aatgattgac
    19081 ttgcaaacaa tcagcatgga cccgttagaa ggactaacgg ttgctgatgt gacagaaaca
    19141 gatgttccga caattgatga aaattgggaa ctagaagaag tactccattt gttagtcgat
    19201 tcgccttttt taccggttgt cacagaagat cggattttca aaggaatcat tacaagaaaa
    19261 gagctgctta aagccgtaaa cttcatggtg catgaattag aacgtcgtaa tatattgtct
    19321 ccgaaaatcg aagaattaaa agaacaaatc gatatcgtga gctaaagaac gagaaactaa
    19381 aagataatca aaaaataagt agaaaaaaca gcgtaccagt tttgacttta tcttgaaaaa
    19441 gaggctggga caaaagcgtt taactccaag aaataagaag gaattcacga aaattacttt
    19501 tcaaattttt gtgaatttca gcttatttcc gaaggagttg cttctgcttc cgccgtttat
    19561 acgtgtttag agcgtgggac aaaagtgttc tttacttttg tcccacgctc tttttagtga
    19621 gattcgttgc atcgtttgtc caaattattt tccgacagca attggactgt tcggaatcgt
    19681 gaaaccagaa gctgtcaatt ctttgacata ggagctcaag aactcttctt ttaaggcata
    19741 ttgttttccg ttcaatgcgt agcagaccgt acgaatcgca aaattgctgt ttccaagatc
    19801 cactaatcca aagatagaag gttcagtttg gagctcttct tggtattttt cagctaatgt
    19861 acgatttact cgatcaatga tctcatagat tttgtcatat ccttcttcag gaacaatccg
    19921 aatatctaaa agtacttgca tatttgcacg agagagattg ctgatcgtgg tgatgtttcg
    19981 attcgggatg aaatggacag taccatccgt tgctttcagc tgaagggtac ggataccaac
    20041 agatacgacg gttccttcaa tcgttaagtt tgctagcttg atgtagtccc caacatccat
    20101 ctgttgttcc atgataataa aaaatccggt aataacatca ctcatgaacc cttgggcacc
    20161 aagaccgatt gccacacctg caattccggc accagccaaa agtgatccga tcggcacacc
    20221 gatagcagat aaaattgcat agataaaaaa gaaaccaagg gtataatgaa aaatagtatt
    20281 taaaagacta tgtaaagtct ttaagcggct ctcgtttaga atggcttttt tagaatactg
    20341 attaaaagac ttatcaatca gatattttcc cacacggtga agaatccaaa aaaggacgat
    20401 caaaaaaatc agatataaac ttttttggat aaaggcagcc aaaatggcgt cccaatcaat
    20461 cccgtcccaa aaccgctgaa acgcatttac tttgctgaca gcttgatctg tcaatgtctc
    20521 gccagaagag tctgtcgtac cggcagttgc taataatgaa aacataaaat cctcttttct
    20581 aaaatttgat tctttctgta ttgtaccaag aagttttcaa aaaaggaaat agcaaaaata
    20641 actataatga aggaaaaaag ctgaaaataa aatgacaaat aatatggata atgataaaat
    20701 gtggagaaaa taacgaaggt ggtaagtata tgcaaatcga ttggaacaat ctaggttttt
    20761 cttatatcaa aactccttgg cgttttattg ccaaatggaa agacggacaa tgggaagaag
    20821 gagaattgac agaagataat tacctgacga ttcatgaagg ctctccagcg cttcattatg
    20881 gtcagcaatg ttttgaaggt ctaaaagctt atcgtcgaaa agacggcaag gtcaatctct
    20941 ttcgacctga acaaaatagt cgacggatga atcaaagtgc tagacgattg ctgatgccaa
    21001 tggtccctga aaagatgttc gttgatgctg tcaagcaagt ggtaaaagca aatgaagatt
    21061 ttgtgccgcc ctatggaaca ggcgctacat tatacttgcg ccctttactg attggggtcg
    21121 gtgaaaacat tggtgtccat ccagctccag aatatttatt tgtcgtcttc tgtacgccag
    21181 taggagcgta tttcaaaggt ggactaaaac caacgaattt tattgtatct gattacgatc
    21241 gtgctgctcc taaggggact ggtgcagcaa aagtcggcgg aaattacgca gcgagtttac
    21301 ttccaggaac agaagcaaaa gaactggatt actcagattg tgtttatctt gatccagcca
    21361 cacatacgaa aatcgaagaa gtaggtgcag caaatttctt tggaattaca aaagacggaa
    21421 aattcatcac tccgcaatcg ccctctatct taccaagtat cacgaaatat tccttgttgc
    21481 agttagctga agaacgacta ggactgcaag caattgaagg agatattttc attgatgatc
    21541 tagatcaatt tgcagaagct ggtgcatgtg gtacagcggc tgttatttct ccaatcggtg
    21601 ggatttatca caataacaat cttcatgtat tttatagtga aacggaagta ggaccagtaa
    21661 caaaacggtt gtatgatgaa ttgacaggta ttcaatttgg agacatagaa gcaccagaag
    21721 gctggattga agtcgtggaa taatttcaaa gtaatgagtt gaaaaaaacg taaaaagaaa
    21781 aaatcaggaa gagactttaa aaagtttttt cctgattttt atatgtttta ctttaaagaa
    21841 tgcaacaaaa gtttatgaaa gatggacacc tttgtcaacg tagataatat caccgatgat
    21901 tccgctggaa agtgggctga ttaagaaagc acaagcatta ccgacttctt cgatcgtcac
    21961 accttgctga tcaggcgtac gagattcaga taactggatc agtttttgat agtctttaac
    22021 acctgtgaca gctaatgttt tgattgcccc agctgagatt ccattgaccc gaattccttt
    22081 aggcgagaac tcagctgcca aataacggat agcagcttca agagaagctt tcgcaatacc
    22141 catcatgtta taattcggga ttgcgcgttc tgaacctaga taagtcatgc taacgatccc
    22201 gctgtttggt gcaagaaacg gttgtgcgta ttttgataca gcaattaaag agtagctgct
    22261 gatatcttga gctaattgat agccgtctct ggaaatatca gacacatttc cggacaattc
    22321 ttctttgttg gcgtaagcaa ctgcatggac aaggccgtgg atctccccag catattcacc
    22381 gatggcattc attgcttttt cgatgctttc gtcgctagaa acatcacatt ctacagtgaa
    22441 tgcttcttcg ccgaccaatt tgactaatga ttttttcatt cgttcatttt ggtaagtata
    22501 gataatttct gccccttgtt tcaacattgc ttcagcacaa ccccaagcaa tgcttttttt
    22561 gttagcgacg cccataatga cgattttttt tccttctaga aatgacataa tgactctcct
    22621 ttgtttctga taaaaatttg atagtcgtaa aaaaatagag aataatagct aaaataactt
    22681 cttgatttct taattattag tcaaaatgtt ttgattgtca aactattttt tcttaaatta
    22741 aaaaaagatt gctaaatatt taggaatatg atactttgat agtcaaagta atgaaaatgg
    22801 caattgcctg aaagaaggag tttaattatg tcttacgtat tatctgctac tgaagtaatg
    22861 gaattgattc ctaatcgtta tcctatttgt tatattgatt atgtagatac tttagaacca
    22921 ggaaaaaaga tcgttgcgac aaaaaatgta acaatcaatg aagatttttt ccaaggtcac
    22981 tttcctgaca atccagtgat gccgggtgcg ttgattctag aaacactggc acaagcaggt
    23041 tcgatactta tcctaaaatc agaagagttt ctaggaaaaa gagcttatat cggtgggatc
    23101 aataaggcca aattccgtca aaaagttgtt ccaggagatg tgctgaaatg tcattttgaa
    23161 atcaccaaaa tgaagggatc agtcggtaca gcgttatctg cagcatatgt agatgataaa
    23221 aaagtctgtg agtgcgagtt cacgttcatc gtcaaccaaa atgcttgact ataaaacctg
    23281 atatagcaaa acaaaaggaa gcttacttgc tttttatgta aaaagaagac gcctgaatcc
    23341 tagcatacgt tgtcatctat gcaggattca gacgttattt ttttattttt gttttgcttc
    23401 ttgcagtata ttgattttat cgatttttac ttcttctttt ggtttgtctg aactatctgt
    23461 ttcgatattt gcaatagcat ccacgacatc cattccttca atcacttggc cgaagacagt
    23521 ataatggcca tctagtgaag gataaccgcc gtttttataa gcgtcgatga ttgcttgagg
    23581 atagtcgtct tttaaaagac catcatgcat atcatctgta ttttgaacga taaagaactg
    23641 gctgccgtta ctgttaggat cttgtgagcg agccatagat aacgcacctc ttatattata
    23701 aaggtggttg ttgatctctg tttcaaatcc ttctccccaa atgctttccc ctccagtgcc
    23761 atcgccttta ggatcgccac cttggatcat gaaatctttg atgacgcgat ggaaagtcag
    23821 tccgttgtag taaccgtctt ttgcatgtgt cataaagttt tcaaccgctt ttggtgcgtg
    23881 ttcgggaaat aatttgattt tgattgtgcc tttattcgtc accatttcga ccagatcttc
    23941 attttcggcg acatctttcg tcaattgtgg taattccaat gcgttcaaat cgacgctact
    24001 ggcagtcgtg ctttccgcag tagatgtact ttttgaactt tctgtagacg aactagaaga
    24061 agtcgtgttg tttgcagaac aaccagcagc aaacagcaat gctgctgcta aactaatact
    24121 taaaataact ttatttttct tcataactgt tcctttccaa tttactattt tgttatcttt
    24181 aatgataaca aaatagaggg aaaataccta cttaaattat tggaatttat catttatttt
    24241 aaaagaaaaa gaaaaggtgt agaccattta ctttgtgttt gctataatgt aagtggatac
    24301 aaaaacgaaa agatgcagga ggaaatggta atatgggaaa attaggaatc tcgatttatc
    24361 cagaacggtc aacatttgaa aaggacaaag cgtacttgga tttagctcat aagtatgggt
    24421 ataaacgggt ttttaccagt ttgctgcaga tcaatgatga taaagaaaaa gttctttcag
    24481 aatttaaaga agtagttgat tacgcgaata gcctaggcat ggaagtaatg gttgatatca
    24541 atccagcgtt atttgaacag ttggagattt cttacgatga cttatctttt ttccataaga
    24601 tgggtgccta cggggtccgc ttagatatcg gattcacagg agcagaagaa gcaaaaatga
    24661 cgcgcaatcc ttttggtatc aaaatcgaga tcaatatgag ttcgggcacg aattacgttg
    24721 acaacatcat gagttattcg ccaaacacgg ataatttatt aggttctcat aatttttatc
    24781 ctcatcgata ctctggttta ggatacgaac actttgtttt ttgttcagaa aaattcagaa
    24841 aatataattt gaatacgatg gcattcgtca attcgcaatc tgctgagttt ggcccttggc
    24901 ctacgcaaga tggcttgtgc acgctggaag accaccgaga tcttgaaatt gcgacacaag
    24961 tgaagcattt aatccttaca ggattgattg atgatatttc tattggaaat gcgtacgcaa
    25021 gtgaagaaga attgaaagaa atggcagaag catttaacgc ggattatcca acattgaaag
    25081 tagatacgga agaaggtatt acagaaaacg aacgaatctg cttgtttgat aaccttcata
    25141 gttatcgagg ggatcgctca gaatatatcc ttcgttcaac gatgactcgt gtatactaca
    25201 aagataaaga tttcccgcct cataatacgc gagatatgca tcatggggat gtactgattg
    25261 acaatgaagg gtacggtcaa tacaaaggag aaacacaaat cgccttgaag gatatgaaaa
    25321 acgacggacg tgtcaatgtt gtaggaagaa tctccgatga cgaattattc ctccttgact
    25381 ttttgaaacc atggtcaagc tttaaattaa ttgaaaataa aaaatagata attagttatt
    25441 gcagaaataa tccgctagaa atagccagtt atttctgctt ttttattttg tttttttata
    25501 ggttatgatt tgtcaaatta agctagaata aaatgcttct tgtacatagc tcaaaaatat
    25561 ttcgattggt gttctgtaat tcaatgattt tcttggaata tgattacgtt gattgctgac
    25621 actggaaata aatgtctgat tcacttttct aaaatccatt gatttcggca gtccattacg
    25681 acgcagaatc ccgttagaat tctcgtttaa tgggcgttga gaaggtgttc cagggtccgc
    25741 aaaatatata tcaatatcat gttggttact aatggctttc cagttagaaa attcttttcc
    25801 acagtcaaac gtaatagatt taaagaagtt tttagggaag cgagaaaacc attgattaag
    25861 ggcagtttca atatctaatg ccttacggcc gttgggttta atcgtgataa tgactttaga
    25921 taatctttca actaaagtaa tgacggcact tttatgatga atgccaacga tcgtatcacc
    25981 ttcaaggtga ccaaactcag aattgaaatc aggataatta tcaggtcgat catggattga
    26041 gcgctgatac tgttgttttc cccgtttttc ctgatggcca ttgggttttc ttttaccttt
    26101 catcggtagt gtgtcaatat caaatattcc tttagaaaat aaacgataaa gtgttctcat
    26161 accgcatgaa acag
//
LOCUS       DAMEEU010000037        26160 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.038, whole genome shotgun sequence.
ACCESSION   DAMEEU010000037 DAMEEU010000000
VERSION     DAMEEU010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 26160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26160
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.038"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(62..1093)
                     /gene="queA"
                     /locus_tag="PB779_001532"
     CDS             complement(62..1093)
                     /gene="queA"
                     /locus_tag="PB779_001532"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HDE0739060.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            1286..2461
                     /locus_tag="PB779_001533"
     CDS             1286..2461
                     /locus_tag="PB779_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HDE0739061.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            2465..3106
                     /locus_tag="PB779_001534"
     CDS             2465..3106
                     /locus_tag="PB779_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739062.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            3103..4020
                     /locus_tag="PB779_001535"
     CDS             3103..4020
                     /locus_tag="PB779_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0739063.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            4017..4688
                     /locus_tag="PB779_001536"
     CDS             4017..4688
                     /locus_tag="PB779_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739064.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(5229..5717)
                     /locus_tag="PB779_001537"
     CDS             complement(5229..5717)
                     /locus_tag="PB779_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HDE0739065.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(5918..6184)
                     /locus_tag="PB779_001538"
     CDS             complement(5918..6184)
                     /locus_tag="PB779_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HDE0739066.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(6184..6447)
                     /locus_tag="PB779_001539"
     CDS             complement(6184..6447)
                     /locus_tag="PB779_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDE0739067.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            6923..7108
                     /locus_tag="PB779_001540"
     CDS             6923..7108
                     /locus_tag="PB779_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDE0739068.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(7250..9073)
                     /locus_tag="PB779_001541"
     CDS             complement(7250..9073)
                     /locus_tag="PB779_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HDE0739069.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(9671..12376)
                     /locus_tag="PB779_001542"
     CDS             complement(9671..12376)
                     /locus_tag="PB779_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HDE0739070.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(12682..13629)
                     /locus_tag="PB779_001543"
     CDS             complement(12682..13629)
                     /locus_tag="PB779_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HDE0739071.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            13819..14088
                     /gene="rpsN"
                     /locus_tag="PB779_001544"
     CDS             13819..14088
                     /gene="rpsN"
                     /locus_tag="PB779_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDE0739072.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(14264..14626)
                     /locus_tag="PB779_001545"
     CDS             complement(14264..14626)
                     /locus_tag="PB779_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDE0739073.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(14637..15758)
                     /locus_tag="PB779_001546"
     CDS             complement(14637..15758)
                     /locus_tag="PB779_001546"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HDE0739074.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(15774..16124)
                     /locus_tag="PB779_001547"
     CDS             complement(15774..16124)
                     /locus_tag="PB779_001547"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HDE0739075.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(16254..17765)
                     /locus_tag="PB779_001548"
     CDS             complement(16254..17765)
                     /locus_tag="PB779_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDE0739076.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(18087..19439)
                     /locus_tag="PB779_001549"
     CDS             complement(18087..19439)
                     /locus_tag="PB779_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HDE0739077.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYLEKEKNKLIDAIKQNLEATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(19592..20668)
                     /locus_tag="PB779_001550"
     CDS             complement(19592..20668)
                     /locus_tag="PB779_001550"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HDE0739078.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            20864..22609
                     /locus_tag="PB779_001551"
     CDS             20864..22609
                     /locus_tag="PB779_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HDE0739079.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(22889..23326)
                     /locus_tag="PB779_001552"
     CDS             complement(22889..23326)
                     /locus_tag="PB779_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HDE0739080.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(23310..24683)
                     /locus_tag="PB779_001553"
     CDS             complement(23310..24683)
                     /locus_tag="PB779_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739081.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(25005..25493)
                     /locus_tag="PB779_001554"
     CDS             complement(25005..25493)
                     /locus_tag="PB779_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739082.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(25515..26117)
                     /locus_tag="PB779_001555"
     CDS             complement(25515..26117)
                     /locus_tag="PB779_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDE0739083.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         7503 a         5561 c         4838 g         8258 t
ORIGIN      
        1 ctttgtcata aaatctttgt aaagcttttt tgttattcaa aactagcggc ttttcataac
       61 cttatttcac gaacatcgca tctccaaaac taaagaaacg atagcgctct tcaatcgcat
      121 gctggtaagc agataaagtc aattctcttc ctgcaaaggc actaactaac atgactaaag
      181 tcgattttgg caaatggaaa ttagttgaga aagcttctac cactttgaat tcatagccag
      241 gcgtaatgaa aatatcagtc catccgctgt ctgctttgat ttctccatta aatttcgttc
      301 caatcgtttc taatgttcga attgaagttg ttccgacagc cacgattttc ccgccatttt
      361 tacgtacttg gttcaatcgc tcagccgctt cttccgtcaa acggtagaat tcactatgca
      421 tatggtgttc ttcaatttta tctacgctga caggtcggaa tgtacctaac cctacatgta
      481 gtgtcagata gactaattca acaccctttg cttcgatctc atcaagtaat tctttcgtaa
      541 aatgcaatcc agctgttggc gctgcagcag aaccattttc tttcgcatag acagtttgat
      601 agcgatctgg gtcttccaga cgttctttga tatatggagg caatggcatt tctcccaatg
      661 attcaagaat ctctagaaaa attccttcat actcaaagtc aatgatccgt ccgccgtgtt
      721 ccaattcttc tttcactact gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa
      781 ctttggcacg tttcgcaggt ttgatcaatg tctcccacgt atctccttgt gtattcgtta
      841 gaagaaggac ttctaaatgc gcaccagtat ctggtttttc tccatataaa cgagcaggca
      901 gaactcgtgt attattcata actagcgcat caccaggctg taactcttca atgatttcat
      961 ggaaatgttt atcttccatc tctccagttt tccgatccaa aacaagtaaa cgagaatgat
     1021 cgcggtcttt taatggtgtt tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt
     1081 ctgttgttaa catatcgtca ctcactttct atcatgtgct tcatcattct atcatgtttt
     1141 tcgttctgtt ggcaaaatca gcactttttc acttctattt tttgttttcc taaataaaaa
     1201 aactacccta tttgtatttt ttcattgttt taggcatact agtaatagat agttcttcat
     1261 tgaaaataga aaaagaggtg gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa
     1321 aggtggaaaa gtcgctgtag aggacgtcaa tctttcattt gaaaagggtg agttcatttg
     1381 ttttatcggt acgagcggaa gcggaaaaac gacgacgatg cggatgatca accgaatgac
     1441 tgatccaaca caagggaaaa ttttgattga tggaaaatcc atccaagaaa ttgatccagt
     1501 ggaattgcga cgtcagatcg gctatgttat ccaaagtatt ggattgatgc ctcacatgac
     1561 gatccgtgaa aatatcactc ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa
     1621 taaaacagct gaaaaaatga ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta
     1681 cccacatgaa ttatctggtg gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc
     1741 gaatcaagat atcatcttga tggacgagcc attcggtgcg cttgatccaa tcactcgtga
     1801 ttccttgcaa gaccttgtca aagatttaca agagcgtttg ggaaaaacga tcgtatttgt
     1861 aacccatgac atggatgaag cgattaaact agcaagccgt atcgccatca tgagtgaagg
     1921 ccgtgtgatc caatttgata caccagaaaa tattttacgt catcctgcaa acgatttcgt
     1981 agaagagttg attggagaag atcgcctact acaagccaag ccaaatgcga caagagtcgg
     2041 cgaagttatg ctaaatacag caatcacgat tacaccggaa aaatcattac aagaagcaat
     2101 caaactgatg agggaaaaac gtgtagatac gttgttagtt accgataatt cgaatgtatt
     2161 aaaaggattt atcgatgtag aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg
     2221 cgacattttg aataaacatg ttttttacgt aaaagaatcc gcctatcttc gtgatacctt
     2281 gcaacgcatt ttaaaacgcg ggctgaaata cgtgccggtc gttgatgaac agaacaaagt
     2341 cgtaggtatc ctgactcgtg catcattagt ggatatcgtc tacgatgtga tttggggaga
     2401 agatcccgca actactgatg ttgcagagtc agctactcct gaagaatcta aggaggtctg
     2461 acctatgcag cagttttttc atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca
     2521 tctttatatt tcaggacttg ctttgatcat tggtatcatc attgctgtac cgcttggtgt
     2581 cttactgaca cgttttccaa aagctgccac gattgtgatt ggcttaacca gtgccttgca
     2641 gacaatccct tctcttgctt tattggcatt gatgatcccg ctatttggcg taggtaaatt
     2701 acctgcgatt atcgcactct ttatttattc attattgccg attttacgta atacgtacat
     2761 tgggatgaaa aatgtcgatt ggaattatcg ggatgtggca aaaggcatgg ggatgactga
     2821 gttccaatcc attttttccg ttgaattgcc cattgctatg ccaacgatca tggctggtat
     2881 tcgtttagct gccgtttacg tgattgcatg ggctacactt gcctcttata tcggcgctgg
     2941 tggtttaggc gatttgattt ttagtggact gaataattac caaccagatc tcattttggc
     3001 aggtacgatc cctgtaacaa ttttagcact attggctgat tggcttctag gtctcttgga
     3061 acaccggctg acaccgatcg cacttagaga ggagaatgaa gaatgaaacg tatactaaaa
     3121 atgaccatgg ttcttttctc tcttcttata cttgcgagtt gttccttccc tggtcttgcc
     3181 agcaatacag atgaagacac catttcgatc acaggtggaa tcacttcaga agcacagatc
     3241 ttagcaagtc tagttgccgg aatggttgaa cattatacag ataaaaatac cgcaatcatc
     3301 aacaatctgg ctactacaac tatcaaccat caagcgatga tgaacggaga tgcttcaatt
     3361 tcagcggctc gctacacagg aacagattta acgactacat tgaaccttcc tcctgaaaaa
     3421 gatccgaaaa aagcgtttgc taccgtgaaa gatgaatttg agaaaagata cggtcaaacg
     3481 tggttcccgt cctatggttt tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca
     3541 caaaaatacc atctatctaa agtcagcgat ctgaaaaatg tagcggatga attagtagct
     3601 ggtgtagata cttcttggat caatcgtaaa ggagacggtt atgacggctt ccaagaaact
     3661 tatggcttct ccttcaattc gatattacct atgcagattg gacttgttta tgacgcagtc
     3721 gaagcaggaa aaatggatat tgttcttggc tactctacgg atggacggat cgccagttat
     3781 gatctagtca tgttggaaga tgatcgtcaa ttcttcccac catatgatgc tgctccagtt
     3841 gtagacaaca agatattagc tgatacgcct catttaaaag aagccttaaa taagttaggt
     3901 cataccatca gtacggaaaa aatgcaggaa ttgaactacg aagcagataa taatctagtg
     3961 gaaccatcag tagtagcaca acgtttctta caagaaaacc actattttga agggaagtga
     4021 agcaattgga taaaatgaat gtctttcaac aatttttcta ttatttccag gaaaatggct
     4081 cctatatctt tgcacaattt atccgtcact tcctgatttc tatctatggt gtcctctttg
     4141 cagcagttgt cgggattccg gttgggatca tgatttctag gagacgtaaa ttagcaaact
     4201 gggtgattcg tttggcgaat atcatccaga cgatcccttc tctagccatg atctccattt
     4261 taatcattgg attaggcctg ggagtcaatg tcgtgattgt tactgtattt ttgtattccc
     4321 tcttaccgat catcaagaat acgtataccg ggatgatcca agtagacaaa aacatccttg
     4381 atgtcggcaa aggcatgggg atgactgcta gacaacgact attcatggta gagttaccac
     4441 tctctgtttc tgttatcatg gcaggcataa gaaacgcgtt agttgttgcc atcgggataa
     4501 ccgcgatcgg tgcattcgtc ggtgctggtg gtcttggaga tatcattatc cgaggaacca
     4561 atgcaacaga gggcacatcg attattttag caggtgcatt gccaactgca ttaatggcga
     4621 tcatcacgga ctggctttta ggtattttgg aaagacggct agatccagcc agccgtacat
     4681 cacgctgatg ttattgtaaa aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct
     4741 tttttagttc tgtcattttt aaggcaataa tccactctga ttcttccctc cttatgggca
     4801 aagagttgct tttcttagct atttatccat tccgtatact ccaacttcat actgccaacg
     4861 ggttcatatc tgcatccacc gactaagttt ttttcttatc cgctaaggca ttttgccaat
     4921 ccattttccc atcactcgtc atggaattca taccacatga tctctaaata ctcgtctgct
     4981 tgttctttga attgggcatc aattcttaca tcctttggcg tggctttcat ttaagccttt
     5041 tccatcagtc ctcgattgtt cgatgccttc agctgcatca tcaaaactgg tgactgccgt
     5101 atcggtaact tcgatcatct tttatacaat cgggaacttg ccatcctcat ccttggctaa
     5161 aaacatatct agccattcca gcttctcgcc atgggaggtt tgcggttcct aaaaccggta
     5221 cacgattctt atggactgca tccgtcgcaa ctagacttgg cgatacgatg atccttcacc
     5281 agaagagcac ccccgtaaac caattgatcg atatattgcc aataagaaaa gacattggcg
     5341 taaaagatat cgatccctcg tgatgcattg ccgttgatac tgctattcat ggccgaaagc
     5401 gccacgactt taacttcttc cgtttgagtg acattcatgt tcggcaatgt cgctttggat
     5461 acccgctctg ctaaaggaac gacactggta ttgtatttcg tatctgtatc ttttccaaaa
     5521 gaccatgcca acgaatcctc tgggaaccaa taagacgact ccggttgatt gtccattgct
     5581 tttttcaaca tacttttggc tgtttctcga taaacgacat ttccaattgt cttcgcctca
     5641 ctttggcgat aatcgatggt cgttgccact gccaacacta acaacgatgc tccaatttta
     5701 ctgattttcc ttgtcacact tcttcctcct tgttttacat aaacccgtca acattccatt
     5761 cctaaactca aacaatgacc cttcaaaggt ggagatatag gaacaaatta aagaaatcat
     5821 gcaataaatc caagaaggtt ggttttagaa caaaaaaaga gtctcctttt tggggagact
     5881 ctttgttaac tatctaaaaa ggttggctct tctcacttca ctcataatgt gtccaggcag
     5941 aataaatttc tacaacttta ttttcctcat caactttgta aaccactcga tgctgtctat
     6001 tcagcctgcg tgagtatctg ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg
     6061 gcatatatgg atcttccttc aatgtctgaa tcacttcttc aaattgtttc tttaaattcg
     6121 tttgcttgat ttttcttaaa tccactttcg cagagttttt gattgcgact gtatagttac
     6181 tcatcaaaga gcttcccaat caatatcatc gatattcgta aagctactgt cgtctttttc
     6241 gcggtctcgt actttatcta aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc
     6301 tctccagtct tccagcccaa tcaatacagc attgtttcca ctacgatcac taataatctc
     6361 gatttcagta tgattttcat ttacctcttt caataactga taaaaatttt tacgagcagt
     6421 gctaggattc atcgttgtat tagccattgt ctctcctcct ttttctgata taattatagc
     6481 gtacttgatt aagtacgtca aaaaaataca ataaagcact taaattcagc aaacttttcc
     6541 tcttttttac atagagaaaa agaccccttt ttagggagga tctttgtcca cgctcacttc
     6601 ttactccttt acgactagcg gtagccaaac gtaaagtaat tggtaacaac gtatcatctt
     6661 tagcaaaggt cgaatccaaa gcctgtgagt ctatgcaaca acaccaatac acgaaggttc
     6721 ctcgttgcag tgtgacttga ttgatatctt gaataacctg aggatacgca cgaaagattt
     6781 gtaacggtta ttcaaaactg attttggccg tcaagtcttc tactgcctca aaaatgattg
     6841 cctctttcgt ctcctgtcat tcatgttcac tatcgatttg atacttgctt agaccgttgg
     6901 gtttgtgaat caccaattaa aaatggcact gagttatggt aacaaaaaat ggtcacttga
     6961 cgaggctgag attcctactt atgaagacac atggcactta agagtcgagg taaaggaaga
     7021 agctgaaaat ataggaggct gtacattatt tggcaaagga ttcggaaatt atgatcaaga
     7081 catcaaaatc aaaatgtttt acagctaaat aggaagaata ataacatttc atacgctgtt
     7141 cccatcttta atggcttata gagggcacct ttagctgaga ataagacaaa acagaccctc
     7201 tagcttcaat taagagctag agggtctgtt tttgatttta aaacttggtt tatttcttca
     7261 aatggtagct ataggtgctg acaacgatat tttcacgcca agacaatcgc aatcttaacc
     7321 gcaaacttgt ttggttatgg agaatattct gccagcgtct gtttggtaca aattgaggaa
     7381 tcaacacagt agttgtatag ttttgtttcg ctgcattttt acttacgata tctacataac
     7441 ggataattgg attttcaatc gagcgataag aagagtggac gattgaaaaa cggacatctg
     7501 ggaaatgctt tttaaattct gcttcgattt ctttttcttt ttcgacatct tcgtctagcg
     7561 aaacatgcat cgcaacgaca taatcaccga tcgaacgtgc gtaattcaac gcaccgatat
     7621 ttacccgtgt cacattcccg actaatacaa gaacggtatt cccgtcataa tcatgtagtt
     7681 ttgcatcatt ttctaaacga agctgttctg ctactttttt ataatgatca tggatcttat
     7741 aaaaaatgaa cataacgatt ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat
     7801 agacaaacaa aatcgcaatg attgcatatg agatgaacgc acccgtaata ttggcaatcg
     7861 atttgcttaa ccatcttttt ccttcttttt tccatttgac gaccatccct gtttgagata
     7921 aagcaaatgg aatgaacacg ccgatagagt ataacggaat caagcgttct gttgagccat
     7981 ggaaaataaa cagcaatacg atcgaaccta gcgctagtgt gataatccca ttggaatagc
     8041 ctagtcgatc cccacgatct tgatacatgt gaggcatgaa tttatctttt gccagattgt
     8101 atgcaagaac tggaaaagca gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg
     8161 tagcaaattg aaggacgtaa tacaaaatac catgtccaaa gacagcttta ccaatttgag
     8221 acaaaacagt gacttctttt tcaggaacga tcccatacca atagttgata aatgtgatcc
     8281 ccacgaagaa gaaacctaag atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg
     8341 ctcttggctt cttaaagaat ggtacagcat tactaatcgc ctccacccca gttaaagagg
     8401 aagaaccaga agaaaatgct cgtaaaatca aagcgataga aacacccggc acagccgctc
     8461 ctggaagtgc agtagcttgc aatggcacag cacctgtcac gatattatat aaaccaacaa
     8521 cgatcagtaa cgagatcaca aggataaatg tgtacaccgg aaataatagg aacgatgcag
     8581 attccctcag cccacgaaga ttcagcatca tcagtagcaa aacgattgtc acagaaatag
     8641 cgacttgatg accgtagagt gctggcaccg ctgatgtgat cgcttcagca cctgctgaga
     8701 cagatactgc tactgtcaac atgtagtcga tcaataaaga gccaccggaa atcaagccag
     8761 cattctttcc aagattctca ctgctgacga catatgctcc cccgccatga ggataagcat
     8821 ggatgatttg acgatatgat agcgttaatg aaatcaataa aataataaca aaagcggcaa
     8881 tgggtagcga ataccagatg gctgcagcag acaaagcgac taaaacgaca acgatttgtt
     8941 ccgtaccata tgcaatagat gataacgcat cagacgacaa taatgccaaa gcagcaaatc
     9001 gggttaattt gtgctcatca ttttcagcag attttaaagg cttacctact aacaaccttt
     9061 ttaagtaatc caatttctaa actcctttac acacaatttt acttcaagtt ttatagtcga
     9121 aaatttatag taaacaagat gttatagtac gctcactgac cttaaaagtc aataaacttt
     9181 aagaaaataa ttggaaaaaa acagaaaaat atcaagcgct ttttcaaacg ctttaataca
     9241 gcaaaaatct aacatttttt tatgggcttt ttctttgaat tctataataa aaggatagaa
     9301 cttgacttag aaaatcaagt tctatccttt ttgatatctt aacttttgga agagagatgt
     9361 aaggctgctt tctacccatc attcttacta ctcgaagcat agcgcagttg tcacaacctc
     9421 ttgataaacg gtgtttaaaa gcttgcatct gcggtaataa gcccaaccaa attaaaaaca
     9481 taagaagctg tttttatttg gtcgttctta ttacttgatg cagagcagct tttttacaac
     9541 ctcttggtac acggtgttca atcagctgac cctcggtatt agctcaaaaa aacggcaaaa
     9601 tatgaggaac tatttttcca tttttttctc taatactcag gtcaaaacac tgatttcaca
     9661 acctcttttt ttaatgaaaa atatggctct catgcgccgc ttctttgaat ttcgtcattt
     9721 tttcttcgat gaacggatag attgccgttc ctacgattcc aaagacaaca aacaaaccga
     9781 tcatgatcca gattgctttc gtagcatttg gccaataaat tcctcctgca gattcccgta
     9841 acaagtttac cgcatgagta aatggcaaga acggattgat catttggaag aatttccctg
     9901 agacttggat cggatagttc ccgcctccgc cagagatcga cagtactaag atgataatag
     9961 cgatcccttt accgacatta tcgaataatg cagccaagac atagacgatc atcatgaacg
    10021 ctaaggcgat caagacagca aatgacacgc tgtagaccgg attttggaca tctactccta
    10081 gtaagaaaat attccctaat gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg
    10141 tcagcatacg agcaacgaat tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta
    10201 aatagtattc tgtcgtagca acacttgaaa gaagaacagc gccgacccac agacatagtg
    10261 cagtataaaa cggggtgcta gctgaaccgt tatttgcgat tggataaagc gcattggttt
    10321 gtagctcaac aggttgtgta aagaagtcac tttcttttgt tgcgtctagt ttcaataatt
    10381 tgatgacttc gcctagatcg acttcttgtt cgccttttcg gatcgcgtct gctgcttttt
    10441 ggataccagc tttgatattt ggccagtcat tgttgatcaa gtccgcagca gcgttcacag
    10501 ctgtttcgac ttctggcatt ttttcattta ctgttgtcaa tgtaccggtg atttcatttt
    10561 ttagtgctgg ccaatcattt tggataaaat cagcggccaa tcctaatttt tgctgaatga
    10621 tcggtaattc attgttgtat aggtctgccc cttcattgat gccattgacg atggtatcca
    10681 tatttccatt cagcattgta ttggcatcat ggatttcttg tccaattgca ggcatttctt
    10741 tttgatattt ttctaaaatt gccactgcat tcgttacagt tgctttcgtt gagctgagaa
    10801 gcgaatcaaa gtcgatctgg tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat
    10861 cgatgacttg gtctagtaga gaagtgacag tggaactgat ttgacctgta ttgataccag
    10921 caatgatgcc attgatatta ttaacaacgg catcaatttg atctagcaat tcatcaatag
    10981 ccttcgtgtc ttcattttga acagctgtgt tcaaagcaga taggcggttt tgcagattgc
    11041 ttagcaaggg ttttaattga tttagctgat caataattgg ctgtaatttc gtatttccag
    11101 cacttgtttg caatttagtc aggaactcga ccagtttatc gattgcattt tgttgttgag
    11161 atattccgtc aataaagccg ttcaatacat tgctgatgtt tttcttttca tcatcagtca
    11221 gcttaccatc ttcaatagct gttcttacag tatctattaa cgaacctgtc gttgttgcca
    11281 cttgtccaat tgacttcaat gtaacatcta cactgtttgt gatgcttggt atcgcatctt
    11341 tcagctgaga ggcacctgat tttgtttggt ttgctagatc acttgcctga ttttctaaat
    11401 ttttcacatc tggcaagata tcttgtactt gttggatgat cgtcaagcct tgttttgctt
    11461 catcgattcc ttggttcatt gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta
    11521 gttgcttacc ggcattttgg atctctggga ttttttcttg caaatcaagg atgatttttg
    11581 cttgatcttt caactcaggc attttgtcat tcaatgcaac gactttttca cccatctcat
    11641 ctactttagg gatgtaatcc acgaattcat ttgctttatt cagtttttcc ttgatttcag
    11701 gtagttgact ttgtaattcg aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt
    11761 catctgttga taaaatcata tctttaactt tattgatact tactaggttc gtatcgatgt
    11821 cgtaacctat ctcattgaat actttcaata aagtcgaact ggctgttttg ataaattcat
    11881 ttgtgatttg cgattggatc gaacttgctc ctttatcggt gattttcggt gcaatcgcat
    11941 tgattttttc atttaccgta tattcgattt ttggtttctt gatatcacca ctagtaaaac
    12001 tcagcagatc ttctgagaaa tcctttggca agtaaatacc tgcgtaatac tttccggaac
    12061 ggactccgtc ttctaattgt tcttttgaat caacgaattg ccatcctaat tgtttatttt
    12121 tatgaagcga ttcgatgact tgctccccaa tggccacttc tttaccttga aactctgctg
    12181 gcttgtctgc actgtaaaca gcaattggca gctctccagt atttccatat ggatcccata
    12241 atgctttgat gttaaaccac gcatatagcg aagggatgat catgatcgcg atgatcagaa
    12301 gtgttgcaat cgggtttttg aaaatccgtt tccagtcaag caaatataat cgaagcgtat
    12361 ttttgattga ctgcatagtt ctcccccttc ttcttttttc agctgaatta ctttaccatg
    12421 tatttcatac ttttttcaat cggctttttt caaaaaagtc gaatttttgg acatatcacg
    12481 gcaattgtct cattgtaatc tcttacatat tgagaaataa ttaaggatta cagcctttac
    12541 tttatcatga aataaaaggg aaagataatt ttatgccaaa gtttttatct attatacgta
    12601 tacgcaaaaa agctaaaaca ttttttgtct ttgcccctac aaaaatgttt cagctttttt
    12661 cgttttttat tcctgtattt cttatttttc gaatgacagg atgattttcc cagcaggagg
    12721 atgtccttca actagctgat gtgcttggat gacatgctta agtgaagcag acagattcat
    12781 tgaaataaaa acatgaaagg ctcctttttg gtaggctttg attatgccag caaaggcttc
    12841 tgcatctaga tattcctttc ttggaacaaa cgattcataa aagccttcct ttttttgccg
    12901 caaatctaga tctgggaggt catttaatgc aacatacctg ccgcctggtt tcatgatctg
    12961 gatgccggtt tctcctttga tacttccttt cgtcgcatcg attacaaggt ctgcctgatc
    13021 agcaaattgc agacctggat ttgttttatc ataagcagca aatgctgaag ctcctaattt
    13081 ttttaccttt tcctcatttt tactggatgc actggttaag attcggattc ccttttcatg
    13141 gagaagctgg atcagacttg acccgaccgc acctgatgct cctagtatca ttacagtatc
    13201 tgtcggctgg atttccgtca aatggttgat tagattataa gccgtaattc ctggcgtgac
    13261 cattccggct gcttcttccc aactcatttt atctggaatt tttgctactt ttgctgatgg
    13321 caacacgact tcttctccgt aagtcccgcc gactgcatgg acagctactc gatcacctac
    13381 atgaacagtt gtgacatctg aaccaatctc tgtcacaata ccagcgccat cattacctgg
    13441 tacataaggg aatttcaatg ttcgtatctc tttcatttct cctaaacgca aggcaacatc
    13501 ataaggattc acactgaatg cttttatttc tacacgaaca tgtccagaac cgacttctct
    13561 gggatgagca tcgatttctt caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa
    13621 tcttcgcatg gtcaccatct ccctttttct ttaagtttac gtttatgcct ttattttgac
    13681 aaaaaaaatg tcttttcgtt ttggcgcatg attcaaaaca aaatagttgt cttttttcgc
    13741 gtaacgtgtt aaattattta tctaaaagcg taaagattac gatttacgct aataaaaaat
    13801 aattggagga atttgttgat ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa
    13861 gaaacgattg aacgctatgc tgctttacgc caggaattaa aagcgcaaaa agattacgaa
    13921 ggcttgcgta aacttccttt agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc
    13981 gatggacgcc ctcgcggata catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa
    14041 ttagcacata aaggtttgat tccaggagta aaaaaagcca gctggtaatc caagtctggc
    14101 tgtaatgtaa aggaggaggg cgcatggacc actccttgga tcatcaaaaa agatacgttc
    14161 gcttcttcta gcagaaatgc tggtactaga agcagacgta tcttttttta cgcacagctg
    14221 gtcctttttt atatgtaaag gctgcatggt tacttcgcta tatttattta gtaacaggag
    14281 tcagtgcttc gatacccaca ctaattttca atgctcggtc aacttctgcc ataatgggtc
    14341 gatccaaatg gcagaccttt tctttcaatc ttgatttatc gatcgttctg atctgctcca
    14401 acaggataac ggagtctctt tctattcctg ttccagtagc tttgatccca atgtgagtcg
    14461 gaagcttagg tttagccatt tttgccgtta tggccgcaac aatgatcgtc gggctaaaat
    14521 ggttacctag attattttga ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca
    14581 cgactggaga aagatcagca aaataaatat ctcctctttt taccatagga tcctccttat
    14641 tcttgatatt ctcttggtat ccgctgtcct aatccgcaag ccacttcata gtggatcgta
    14701 cctaattgat ctgctatatc ctgcatagtg atttctttgt ctgcattttt gccgataagc
    14761 gtcacttttg ttccgacagg aaattcttga ggcaatcgga tcatcagttg atccatacat
    14821 acacgcccaa tcgtttcaca gtagttccct tctaccaata gagaaaaacc ctgcatcttt
    14881 cgtggccagc catctgcata accgatcggt atcgttccga tccactctgc ttcaggagtg
    14941 atatatgttt ctccatagcc gattccttca cctgctggga gttttttgac ttgaatcaat
    15001 tcagaaacca gctcaagtgc tggctgcaat ggataaactt ccggtagtgc gtgcccagag
    15061 ggattaagtc cgtacattgc tactccataa cgaatcatat tgccgattgt ttcatcatgc
    15121 cataaagccg ttgcactatt gctgacatgt acatatcgag gaagttcggg aagttttttc
    15181 agcacttcta taaagcgttc tttttgcaga ttccaatatg tatcatctgc ctgatctgct
    15241 gtagaaaaat gggtaaataa accttcccat tctaatacac gactttcttt gatgaatgca
    15301 gctgcctctt ttacttcttc aggtgtacaa aatccgatac gacccatccc agtgtctgct
    15361 tttagatgaa tcgaaagagg cgtctctagc ttacttttct ctaaaacagc agctgctgct
    15421 tgcaaccatt cccgtgtacc tgcagttact gataaatcat gagcaacagc tacagtcagt
    15481 gcgtcgtaag gaaccatatt caagataagg atgggctgag taaatccagc ttctctcaac
    15541 tcgactcctt catctaaatt tgaaacacaa aagcccgaag ctccacctgc aactgctgcc
    15601 tcagctgttt caatagctcc atgaccgtat ccgttcgctt ttactactgc aaacaattct
    15661 tttccttgcg gaagtcttgc aacttcattt gctacatttt cagttatagc ttttttatgt
    15721 atcactgctt tcgttgggcg gtgccaagcg acaaccatcg tttttccttc tttctagtct
    15781 tccaaaataa tttgtgcaaa agctgtttca tttgtatgag taatactgac ccatacattg
    15841 ccttcatgag gtgaacgcgt cacaacaggc tgaccatttt cattttttaa aatctcgaca
    15901 tcttgaaagg taacttttcc gatcccagtt ccccaagctt tagagaaagc ctctttgcaa
    15961 gcgtaacgcc cgcctaaaaa ttctacttgg cgatgaaaag gcaaggactg gaatagtttc
    16021 atttcatcag aggtcaagat tcgtgcaatg aattttggtt tttcttcgat cagccgagtg
    16081 atcctaggaa gttcgactgc atcgatccca attcctttta tcatatgctt ttctcttttc
    16141 aataaattta gaacactctc attctaccaa attataacca ttttgccaca aataagtcca
    16201 caaataacaa aaatgaaagt ttctcttaaa aaagagaaac tttcatttta tgtttaatcg
    16261 ttatttgaac ggattacaaa tccgcgtttt ttatcattgt gacgtttacc gccatctttt
    16321 tggctgttat tatttttgct ataaccgcct tttgatttgt ttccacgata attaccgccg
    16381 tcacgacgat tacggttgtt tccgccacca cgtttgccat ttttattgta tccttttttc
    16441 tgcattggca atgggcgttc tggtgtgatc ttcactggca ctgcatcagc tggatctttt
    16501 gctgtcgttt ttagcaaaag tgcaactaaa tcttgtgcag aatattcttc taataattta
    16561 tctgctgttt gcaggtattt atctagacca ttttctgcaa gttttgtttc gatttgttca
    16621 actgcagcac ctaattgacc tttgaatgct tctttttcgg ttggtggacg taaagtcgtc
    16681 atccgttttt tcgtcaagtt ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg
    16741 aaagtcacag acataccgcc ttttccggca cggcctgtac gtccgatacg gtgaacgtag
    16801 ctttctggat cttgagggat atcatagttg tacacatgag tgacacctga aatatctaat
    16861 ccacgtgcag caacgtctgt cgctacaagg atatctaaat gaccgctctt aaatgaacgc
    16921 aatacgctca ttcgtttttg ttgagacaaa tcgccatgga ttccttctgc acggtaaccg
    16981 cgtgcttcta atccgcgtgc caattcgtct acacggcgtt ttgtacgtcc gaagacgatt
    17041 gttaattcag gtgtttgaac atcaaacaag cgagtcatga tatcgaattt ttcgtattct
    17101 tttgcgcgga catagtattg atcgatcaag tcagctgtca tttctttcgc tttgatcttc
    17161 acatgatgtg gatttttcat gaatttaacg ccaatattct tgatagctgg cggcatcgtt
    17221 gctgagaaaa gtaatgtttg tctttgatca ggaacttgtg aaatgatttt ttcgatatct
    17281 tccaagaagc ccatattcaa catttcatct gcttcatcca aaactaatgt ttgaacggtt
    17341 ccaagtttca atgtgtggcg gttaatgtgg tcaagcatac gtcctggtgt acccacaacg
    17401 atatgtggac gatctttcaa gccacggatc tgacggccaa tatctgctcc gccgtaaacg
    17461 gcttgtacac gtactttttt gtcgcgccct aaacgatata attcttcttg tgtttggata
    17521 gctaattcac gtgttggtgc gataactaaa ccttgtaatt cgtgacgatc tggatcgatt
    17581 ttttctaaca ttggtaatcc aaatgcagct gttttccctg tacctgtctg tgcttgtcca
    17641 ataacgtctt ttccagctaa tgctagtgga atcgtttctg cttggatagg cgttgcttct
    17701 tcaaaaccag cgcgttcgac tgatttcaac aattctggtg ataattctag ttctttaaat
    17761 ttcaaatgaa tcctcctata tggttgttaa ctgaggatgt agcttttttg ctaccccgtc
    17821 gatttgttcg gtcaaagtgt attgtttctt tttgacagtg gccacgcacg tttttatcca
    17881 ttcttagccc ctgtggcacc accgaaaaat cactttgcga agtttaggca ttagaaaagc
    17941 caaacgggtc gcgttcagct ttatcattat tatgacatct ggcttcaaca agttgtttct
    18001 atggcaaaac cagtccaatt tctcttcatc tttcggcaat aggttattct aacatagttt
    18061 ttcgttttct gcaagtttac agatttttat ttcatttgct gaagttgttc taccacttca
    18121 aataagccca tgctgttgct gccttttagc ataatactat ctgttgcttc aagattttgt
    18181 ttgatagcat caatcaattt attcttttct ttttccaaat agaacacagg tagttggggg
    18241 tatttttggt tcaattcttc ttttagtgca tgcatttgtt ccccataaag gaaaatcatg
    18301 gcgaatttct caggatcgat atgttcactc atttgcgcat gcatatttaa agactctttc
    18361 cctaattcca gcatatctgc taacacagcg attctgcgtc cttttgttgg cagattttta
    18421 aaagtatcta ataccagtcc catggctgtt ggatttgcat tgtagacatc gctcaaaata
    18481 gctgcaccat ttcctgccgt tagccattcg gttctgtttt gagtgataga aacatgggcg
    18541 agcccttggc gtatctcagg tatggacagt ccaaagaagc gcccgatcgt atacgcaatc
    18601 aaagcattcg ttacattata acttccaggc agcgggatcg taaatgtttc tccttctact
    18661 acaaaatcgg tttgtgcttt tccttttgct gtcacttccg catgaacatc gccatttcca
    18721 ataccgaatg ttgtgactgt ttgtactaat gttgccgtta aaggtgtcag caacggttca
    18781 tctgcgggca caacgagtaa tccgtctgat acaagtccgt cagtgatttc cattttggct
    18841 ttagcgattc cttctcgcga cccaagattt tctatgtgtg cttcaccgat cattgtgatt
    18901 gctgcagctt ttggttgagc cataagtgaa agttccgtga tttcattggc gtgatccatg
    18961 cccatttcca aaacgatctt ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga
    19021 ccaatattat tgttgtaatt tccttgcgtc ttatatgttt tgtatttttc agacaagaca
    19081 gacgcggtta gatctttcgt ggtggtttta ccattgcttc ctgtaattgc aacgacttct
    19141 gcgcctactt tttccaagta ataggttgcc aattgctgca tggctttcaa aggatctgct
    19201 acaggaataa ctggaaaatt ttttggagct tgttcaacag gcaagctcca aaatgaagca
    19261 gatgctccgt ttgtgatcgc ttgctggata aattcatgtc catctcgcgt accagcaaga
    19321 ggaacgaata aacttccttc ggttatcttc cggctgtcaa attcgacatt ggtaatcttt
    19381 gtcagtgcag agcattcgct gcccacggct tgtgcaattt cttgtattgt tagattcatt
    19441 gagatctctc ctaaaaaagg ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg
    19501 actctcactt ccaagtaaat ttctctattc gtatttagaa gctagaatga acgcggttac
    19561 gcaatcactc cagcctcttc tttatttctc tttattcatt tttttcaaaa aaagattgac
    19621 gctgatggta tcgattcatt cctaactgga tcagttcttc aatcaaatca ccgtatttca
    19681 agcccatatt ttcccataag agtgggtaca tactgaactc cgtaaatcct ggcatagagt
    19741 ttaattcatt caggaataat tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc
    19801 cgcttccacc taacatcgtg taagctaact tcgcgtactc ttgcgctttt tgataaactt
    19861 cttctggcac ttcggctgga atctgcattt cgattttatt attgatatat tttgcttcat
    19921 aatcatagaa tgctacgtct tttacgactt caccaggcaa agtcgtccga acgtcttcat
    19981 ttcctaatac agcaacttcg atttcgcgcg cttcaattcc ttgttcaacg attgctcgag
    20041 aatcatactg ataggctgtt gctaaagcat tttgcagctc ttctcggttt tctgcttttg
    20101 taatgccgac actagaaccc atattcgccg gtttgacaaa catcggataa agcaaagaac
    20161 cttcacattg atcaaatact tttttaggat tttctttcca ttgattctta agtactggta
    20221 cataaggaac ttgcggcaca ccagcagctt gtaaaatata cttggtcatg attttatcca
    20281 tggcacatgc actggtcaat acgcctgcgc cgacataagg catattcaat gtctctaaga
    20341 agccttggat cgttccatct tccccgtttg gcccatgtaa aactggaaaa acgatggctc
    20401 cttcttcttt gatttcgccc ggattgatca cttttcctgt aaagccttcc tctgtctgtc
    20461 cacttgggtc ccatgaaaga tgcaagacat ctttgctggc aggtttttct gttagtaatg
    20521 gacctttgac ccattgtcct tcttttgtaa taaatacgag ttgaacttgg taataattat
    20581 aataaatggc atttaaaact gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc
    20641 gtccgccata tagtaaagta atcttcaaaa gattgtcctc ctgtattcta aatcgttcag
    20701 tgatttactc tcatatttta gcacaaaaca aaaataaacg aataacttat ttataaaaaa
    20761 acgagccagc ttctaaaaga acgagcgtca tttatttttt gtcagctaga ttatttgtcc
    20821 cgttttttat aaaaagttat gataaagaaa aggagggatg atgatggcgc aaacaaatcc
    20881 acgcagccgc ttggcagaaa tcattcgagt gttcatcaat tacaatgtag tgccaaactt
    20941 tgtacagcaa aaaaatcccg aacaggtaaa aaaagccttt gaagaactag gccccacctt
    21001 catcaagata ggacagatgc tttctgttcg agaagatttg ctttcttctg ccttcactca
    21061 aacattcaaa acattacaag atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac
    21121 gatcgaaaca gaactttctc tttcattatc agatatattc gatgattttt caaaatcgcc
    21181 ttttgcctct gcttctatgg ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt
    21241 agtcgttaag atccaacacc ctaacatcgc cgaagagatc cgacttgatc ttcaactatt
    21301 tgaacgagcg atccctttga tcaaatacat tcctgaaact agcgtagttg atctaaaagg
    21361 ggtactccaa gaagtaaaac gttccttgat caatgaaatg gacttcttaa aagaaagtca
    21421 aaatggcgaa caattctatc aaaagaacaa tggctggaaa gagatccgca gccccaagat
    21481 ttatgacgct ttttgttcga aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt
    21541 gaatcattta atgaacgccg aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa
    21601 gcagctgaaa caagaagttg caaagctttt agttgagaac tttatgaaac aggtgtttga
    21661 tgatggtttt ttccatgctg atcctcatcc agggaatctg ctattccatg tactaacaaa
    21721 agaagaacag acacaagcta gccgaaaaac tgaaacagtc catgaaaaag agttcggttc
    21781 ctttgctttt cgagcctcca cttctgcaga agaccctgtt gcgccatata ccatcaacta
    21841 catcgatttt ggtatgatgg ggcatctttc tgcaggactt aggcaaaaac tcacacaagc
    21901 cgttttagcg ctgtatacga aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg
    21961 tcagcaagaa ggctcgtttg atgaaagtcg gttccaccaa gaactgacaa gttttcttga
    22021 acagtattat gattctccta ttgatgaaat caacttgcaa gaagtattca cacatgtcgt
    22081 gacgatttgt catcaaaata atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc
    22141 atttgggaca ttagaagggg tgatccgcgt cctcgatcct gaagtttccc tcatggaagt
    22201 cgcttcgcct tttgctcaac attattttct cactcatctg gatgtagaag atacattgaa
    22261 acaaagcgga ttagacttat tggaagggat gaaggctgcg cctaagatcc ctcaacagct
    22321 ccaccatcta ttagaaatgt ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa
    22381 gcaagacaaa ttattgagca ggatcgaaag tatgatcaat cggcttgttt tcggtatgat
    22441 tttagctgca ttgatcgtag ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc
    22501 agaggtcgtt tccttattag ggatatttac gtatgctatt gccgcattcg tcattatttt
    22561 tttggcaatc gatgcattga tccaaatgta taagaagagg aaaaagtaga aaaaggttgt
    22621 gacagaaaga atcagcttca agaaataaga aggggtttta cataaattgt ttctcaaatt
    22681 tttgtgaaaa ttcggcttat ttttcgaaga ggctacttct gaaacaccga gaataaaaaa
    22741 tgtgaaaaag ctgttctgca cccagtaata agaacaatca aaaagggaac atggaacaca
    22801 tttatcctgt ttccctgttc cctttttgat gtattcgagc ataaataaaa taccttcgtt
    22861 acctactatc ttctgtactt ggtaaacctt agtcaattgc cttttttaac gcttgacgaa
    22921 aagacatatg atctttctcc gtaaagggtt ttggaccctt tgtccttatg ccagcttttc
    22981 ttaactttcc actatgataa cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt
    23041 cttttccaga gtgatggaac actcgcacac ccttcggcaa tacaagtgaa gctaaaccat
    23101 aatcttgcgt gatcaaaaag tcattcttct taaccatacc gacgatttta taatccgcac
    23161 tatcagctcc gcggtctacg tagacgattt ggacatgatt agcgtattct ttggtcgtat
    23221 aatggtccac actggtcacg ataaccacgt caagaccata ggattctcct aattttatga
    23281 catcttcttt tactggagaa ccatctccat caatgaatag cctcattctt tttcgccttc
    23341 ttccataaat gataaacagt tactaatccg ctcagtaaaa gaccaacatt gatccatttt
    23401 gccaagataa gcagttgtac actttctatc ggcactgatt catggttcag cgtgatcaat
    23461 aatagatgga ttggctctcc catttctttt gctaaaacaa acaaaagcgt catcaataaa
    23521 aactggtgga tcacactccc tttattttga gtagtatact tgacaacgat ccggcgatcc
    23581 attggaatag ctgtatcagt ttgataatat tccttattta gccagctgcc tgttactacg
    23641 tgccagaaac taagcagaaa gacacctatc gcaaaaccat ttggaatcaa gaggaccaat
    23701 aaagaagaac tcagtccaag caattgcata gccaatggag accatgttaa acgtttcaaa
    23761 atccatggtc cgactatttt tgctgcaatc aagcctgctg cataaggcaa atacataaaa
    23821 atcgaaagtt tttctaatcc gtacagtatg ccaacataaa aactgctaaa taaaaaaagg
    23881 aaattcccta gcattccatt tagaaaagta aacagattta gccagcttgg caacttccat
    23941 tccttcttct ggtgtcctaa aacaaacacg aacaagatga acagcagcaa gaaaccataa
    24001 atagcaagat caaaaagcct ttcatcgaat aacaatcggg catttctcaa aagaaacaat
    24061 aagccaaaga atatcaaaaa taaaacaagc tctcgcgtag ctaccagatt tcttttgatg
    24121 tctttgaaat ccagttcgta acgcggataa tgactaaccg tatggtaggc catgacgtaa
    24181 aaaagtgtat aaatagtaaa gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct
    24241 tgatacagga gaaatagcca gatagctgca aataagtact ttttcccatc catattgata
    24301 aaaccttgcg tcttttcgtg aaaattgacc gtggtattag caggtacaag ccatgctgca
    24361 ctcagcccta gcaaaacact tgaaaaataa aataaaggaa aataaaatac gcctaatatt
    24421 ccaagcaatg aaccagcacc accaatcagc agagcgatca tcagcaacgt gtaactatct
    24481 agaccaaatc gtagactgtt gactaaaaat agtccagtca tccgaaaggc ataaaacagc
    24541 gtaaatggca aaatcgtcag ccaattatgc gagtctgtta gtcccaaaaa taaaagataa
    24601 ggaataaaaa taaccgtgtt acttaagata aagggcgttg tttgtgtaaa attacgccca
    24661 aatcgtttga gtttttcgaa catgacaatg gctccttaaa cagtcttata actaatctgc
    24721 tcttcgattt tagcattaaa ggggaaataa accaatttta cagaatatat tcttgtaaaa
    24781 aaaaatacag aaagaagcat aagcttcttt ctgcattttt acggtacttg attactcaag
    24841 cagacaagcc cttctccaca aaagtcttgc ccgacacccc tgcatccggc aggtgataaa
    24901 gatagaaatc aattatcctg tgcctccaaa atcaattagg agctctgtaa accagagtcc
    24961 ttctcgaccc gtcgcataaa tttactttaa cacagttcct atgtttatgc gagagctttt
    25021 ttcattttat aatcgaccat ttgaaatcct tgaccgatat ctgaaataag ttcttctgta
    25081 atctcaaatc cttcatgctt ataaacctcg attgcttgat gattcccctg attcactcgc
    25141 aaaaagatct ctctttcctt tgtttgcgca gcaagttctt cataccagcg aaaaactgaa
    25201 gaagtcaatc cttgaccacg tactttattt agcaaatata atttacttaa ataaattttt
    25261 ccatttatct cttcataagc agtgtaaccg acagtctttt cttcgctttt taataaaaag
    25321 taggacacac cttctgtcag ttctttttga atctgttttt ttgactgata agttttcagc
    25381 atgtaatcca cttgtttttg accaatgatc ggcacaaaag cttccggcca tacttcttgt
    25441 atgactgcca tcagctcatc cagttcattt tctgttactt ttattttttc catacaccca
    25501 cgtccttttt tacattataa atgaccttgc gcttgatgga ataaaaagag catgatcatg
    25561 ctatacacac ccaccgacca tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa
    25621 gataatttcg tcaaaccagc tactagacag atcaagtcgt ctggcgcaaa gggaagcagc
    25681 aaggtaacaa ctagtacttt tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat
    25741 ttctgatact tttttggcga taaaataagc tggacaaagg ctacgccata gtaacggaca
    25801 agcaaaaatc cgattgcttc cccaatcact aggccaatac aactatataa aagcccaaat
    25861 ccattgccaa acatcagcat gcccgctact gaggagatcc ctcccggcaa aataggaatg
    25921 atcacttgga tcacttgcaa cagaacaaat atcatcactg catacttgcc aaattgctgg
    25981 ataaacgctt gcaaagacgt gctcgatcga aaaatcccat gatgataagc ataaagaatc
    26041 aacacaaaga aaaaaaacag accaataatg ggcatgatct gaagacattt ttgtaaaact
    26101 gatccttttt tagacatcta tattccccac atcttttttc atttattaaa actgcctcct
//
LOCUS       DAMEEU010000038        25897 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.039, whole genome shotgun sequence.
ACCESSION   DAMEEU010000038 DAMEEU010000000
VERSION     DAMEEU010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.039"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(179..586)
                     /locus_tag="PB779_001556"
     CDS             complement(179..586)
                     /locus_tag="PB779_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDE0739084.1"
                     /translation="MKFLRKAGVKIGDVIIIGILIIPSFIPLFVFSIEKENETTEDAI
                     KYAIVQIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVR
                     TGWISKPGQTSICLPHKLVISIEKKESKDYYIY"
     gene            complement(581..1785)
                     /locus_tag="PB779_001557"
                     /pseudo
     CDS             complement(581..1785)
                     /locus_tag="PB779_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180763.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
     gene            1911..2129
                     /locus_tag="PB779_001558"
     CDS             1911..2129
                     /locus_tag="PB779_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739085.1"
                     /translation="MSQYCHLTILKRERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTNHLPKRKKIMLIEEKNADVITF"
     gene            2150..2785
                     /locus_tag="PB779_001559"
     CDS             2150..2785
                     /locus_tag="PB779_001559"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDE0739086.1"
                     /translation="MVRHLFVDFQWSPEKISNRLKHEHMDFSISFITIYRAICNDLFD
                     TEPLSHGNKGLIRSLHHRGKTRHTKNHVESRGKICLTHSIHGHPKSADDRSDFGHWKA
                     DIVAGKTSGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEVLNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(2978..3217)
                     /locus_tag="PB779_001560"
     CDS             complement(2978..3217)
                     /locus_tag="PB779_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739087.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYQFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(3241..4764)
                     /locus_tag="PB779_001561"
     CDS             complement(3241..4764)
                     /locus_tag="PB779_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HDE0739088.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLIQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKLNKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNEMHNWPTFYPASLSEHEIAQEMMAH"
     gene            complement(4782..4904)
                     /locus_tag="PB779_001562"
     CDS             complement(4782..4904)
                     /locus_tag="PB779_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HDE0739089.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKQNKMKKLA"
     gene            complement(4934..5917)
                     /locus_tag="PB779_001563"
     CDS             complement(4934..5917)
                     /locus_tag="PB779_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HDE0739090.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVIADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLEKFNHPLVFESDSSENH
                     YNGKHYHQHHQEHEFKSILLTSDQDIKKDFLFQLIDRLILTNQGSLYRFKGLIALQDQ
                     DFIVAIQGVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            complement(5941..6090)
                     /gene="rpmG"
                     /locus_tag="PB779_001564"
     CDS             complement(5941..6090)
                     /gene="rpmG"
                     /locus_tag="PB779_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDE0739091.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            complement(6111..6488)
                     /locus_tag="PB779_001565"
     CDS             complement(6111..6488)
                     /locus_tag="PB779_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739092.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            complement(6520..6699)
                     /gene="rpmF"
                     /locus_tag="PB779_001566"
     CDS             complement(6520..6699)
                     /gene="rpmF"
                     /locus_tag="PB779_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDE0739093.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            complement(6714..6983)
                     /gene="rpsN"
                     /locus_tag="PB779_001567"
     CDS             complement(6714..6983)
                     /gene="rpsN"
                     /locus_tag="PB779_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HDE0739094.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            complement(7506..9272)
                     /locus_tag="PB779_001568"
     CDS             complement(7506..9272)
                     /locus_tag="PB779_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739095.1"
                     /translation="MQMIGGLTMKSFYKNKFALTNQGAEDLVKASISSFFVYCINMVP
                     AFIIMMLIDELVLENVKPPWLYFTVSFVTLLFMYWLLDREYENLYNSTYKESAHLRMQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKIVDQGTHSELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            complement(9232..10986)
                     /locus_tag="PB779_001569"
     CDS             complement(9232..10986)
                     /locus_tag="PB779_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739096.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLK
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQHLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHQVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            complement(11096..11665)
                     /locus_tag="PB779_001570"
     CDS             complement(11096..11665)
                     /locus_tag="PB779_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HDE0739097.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVASWALMQLGSAAGQWIPIWFFTDRFRQDWIDKGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            complement(11683..13098)
                     /locus_tag="PB779_001571"
     CDS             complement(11683..13098)
                     /locus_tag="PB779_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HDE0739098.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQDPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            complement(13109..13777)
                     /locus_tag="PB779_001572"
     CDS             complement(13109..13777)
                     /locus_tag="PB779_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HDE0739099.1"
                     /translation="MSKINPLTLITLNIFFPVIIFLGKGNIFQVGCFIIATVLVLMFR
                     KIKTCIYFILIYSVLFLVMKIIDAIKIEFFTIFFGTSLYIVFRMLPVVMISWLLVSVY
                     TSNELLSSLEKIHLPKKIMLSITVVIRFFPTYRSEIRMIKESLKMRNIRLSFFQPLQY
                     LEFLLVPVLIRATMIAEEMTANAITKGIESPVKRSSYYKTNMSLLDYIILFSVTIFFL
                     SILI"
     gene            complement(13908..14492)
                     /locus_tag="PB779_001573"
     CDS             complement(13908..14492)
                     /locus_tag="PB779_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0739100.1"
                     /translation="MESGLSHFEKVGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            complement(14827..15057)
                     /locus_tag="PB779_001574"
     CDS             complement(14827..15057)
                     /locus_tag="PB779_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010708749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HDE0739101.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLTKLRYEDYLDIGFQLTDKGKKFIDDYKKRF"
     gene            complement(15072..16019)
                     /locus_tag="PB779_001575"
     CDS             complement(15072..16019)
                     /locus_tag="PB779_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HDE0739102.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            complement(16019..16861)
                     /locus_tag="PB779_001576"
     CDS             complement(16019..16861)
                     /locus_tag="PB779_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HDE0739103.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            complement(16994..17719)
                     /locus_tag="PB779_001577"
     CDS             complement(16994..17719)
                     /locus_tag="PB779_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HDE0739104.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIFIGEGGTA"
     gene            complement(18180..18494)
                     /locus_tag="PB779_001578"
     CDS             complement(18180..18494)
                     /locus_tag="PB779_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDE0739105.1"
                     /translation="MHKDLLIICETGISASLLVSKMLETIRAKNLSYEIDYATIRNVE
                     EKLNYKDYDVLLLTPQVARSEEKVKEIIKKEKCTAQIVYIKQEDFRYMNIENIIASIE
                     ED"
     gene            complement(18510..20105)
                     /locus_tag="PB779_001579"
     CDS             complement(18510..20105)
                     /locus_tag="PB779_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HDE0739106.1"
                     /translation="MNLFSIISFLVIVICVWLFAYSRSRSVDTSGSEGFFMGGRSLTA
                     LPIAGTIIMTNLSTEQIVGQNGQSYHAGMEVMAWEVTATIAIVALAVIFLPKYFKYGI
                     NTISDFIEIRYDTVTKRIISILFIVTYMTSFLPVVLYSGSLVFNKIFHIDELLGVQPI
                     VAIIIVAMAIGIVGILYLLIGGLSLSANSDSIYGVGLLACGLLVPILGLMKLGDGSFV
                     GGIEHVVVNTPWLLNSVGSIDSAVVPWPTLFTGMLFNNLYFWCTNQMIVQKALSGKNL
                     AEAQKGAFLVGVFKILGALFLVFPGIVARNIFGDSLMSNPDNAYPFLVSEVLPKMIFG
                     IFAAVIFGAILSSFAGALNATSTLFSLDFYKPLINKKANDKQIARAGKTVTVVVGIIS
                     IIVAPFISFAPAGLYQFVQEFNGLYNMPLLVIILFAFYSKKATAFGAKTTIAVHIVLY
                     ALSKMLFQNIHFLYVLTALFVLDIIILMVVSKLKPDGEFVLNSFDTKVDIEPWKYTKV
                     TAIALVVIVILTYVAFSPIGFAG"
     gene            complement(20128..21018)
                     /gene="iolE"
                     /locus_tag="PB779_001580"
     CDS             complement(20128..21018)
                     /gene="iolE"
                     /locus_tag="PB779_001580"
                     /EC_number="4.2.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010777829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="myo-inosose-2 dehydratase"
                     /protein_id="HDE0739107.1"
                     /translation="MTKQIQLAIAPIAWTNDDMPELGSENTFEQCISEMALAGFTGTE
                     IGNKYPKDPEVLEQYLNIRGLKVASAWFSAFLTTKPFEETAEAFKAHRDFLHAMGAKV
                     IVVAEQGHSIQGIMTAPVFDDKPVFTDEEWKKLAEGLEKLGDLAHEKDMEIVYHHHMG
                     TGVQTTEEIDRLMEMTDPDKVKLLFDTGHLVFSGENPIAVYNRHQDRIKHIHFKDIRQ
                     ETAEEVEKEKDSFLNGVKKGVFTVPGDGMIDFTPIWTAIHASDYEGWIVVEAEQDPAK
                     ANPFEYAVKARSYIREVTGL"
     gene            complement(21035..22060)
                     /gene="iolG"
                     /locus_tag="PB779_001581"
     CDS             complement(21035..22060)
                     /gene="iolG"
                     /locus_tag="PB779_001581"
                     /EC_number="1.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol 2-dehydrogenase"
                     /protein_id="HDE0739108.1"
                     /translation="MNNIRVGIVGLGRLGKVHAQNLATGVSCCELTAACSLVETELAF
                     AQKKLGVKHTFSSYEEMVKSSVIDAVFIVSPSGFHCDQVRLAMENGKHVFTEKPLGLE
                     VEDIKKTQKVIEEHPEQVFMLGFMRRYDESYQYAKKMVEDGEIGEITLIRCYGIDPSE
                     GLESFVKFAMNNDSGGLFLDMAIHDIDLVRWFTGQEVDQVWAIGKNAAYPELDQAGEL
                     ETGAAMMSLSDKTIALLVAGRNAAHGYHVETEIMGTKGMLRVAQAPEKNLVTIMNDQG
                     IIRPCSQNFPERFREAFIREAQEFVSCIQEKRQPAVNAEDGLQSTKIALACQESFDTK
                     SLVQLKK"
     gene            complement(22084..23091)
                     /locus_tag="PB779_001582"
     CDS             complement(22084..23091)
                     /locus_tag="PB779_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016634067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0739109.1"
                     /translation="MRVKVGVIGTGAIGIEHIDRINQKTQGAYVTAVSDINVKAAKEV
                     AKRVDAKFFETGEALIASEDVDVVVVTSWDPTHEQYVLEAIKHGKYVFCEKPLAMDAA
                     GCRRIVDAEVAYGKKLVQVGFMRRYDRGYIELKEAIESKQYGEALMMHCAHRNPSADE
                     NYTTPMAISNTAIHEIDVLRWLLNEDYESVQMILPKKTSNSHADLHDPQLLIFQTKSG
                     VTIDLEIFVNCRFGYDIKCDVVFETAEVGMTDPAYTRIKSEEKNYTPVSPDWQTRFLD
                     AYDYEFKLWIDSIKNDAVVGPTAWDGYVAAITMMACHESRETKTKVMIQMDERPALYN
                     E"
     gene            complement(23204..24364)
                     /locus_tag="PB779_001583"
     CDS             complement(23204..24364)
                     /locus_tag="PB779_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HDE0739110.1"
                     /translation="MNIQLKMPANLRIGGGTIQFLMEESEQLGNKPLIISDTVMEQTG
                     HLQKIKELLGKTDDQLAEYTDIQAEPTQENVYDALKLFQKHQCDHIIAFGGGSCLDTA
                     KVVAVLAANQLSLEAIHARNFDQLQAGIPLIAVSTTAGTGSEVTDVAVITNTKTAVKM
                     MMKDLVFMPQISIVDSDFTKTVPPKVTAATGVDALCHALESYVSVKANEVTQLFSLEA
                     MKKILNTLSQAYENSDDTEAREQMSLASTEAGIAFSNASVTLIHGMSRPVGALFHIPH
                     GISNAMLLPVFFEFSKDAIQTELATIARFIYPAAEDLSLEEAADYLIKKIQELCEQLS
                     IPTIRDYGIDQQAFMAALDKMAADALTSGSPQNNKKVPSHSQIKELYVQAYG"
     gene            complement(24440..25894)
                     /locus_tag="PB779_001584"
     CDS             complement(24440..25894)
                     /locus_tag="PB779_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010825391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-acylating methylmalonate-semialdehyde
                     dehydrogenase"
                     /protein_id="HDE0739111.1"
                     /translation="MTRFLRNYIDGRWVASRSTEFEEVMNPATEEALANVPLSSKAET
                     AEAVKAADAAFQTWKKVPVPVRGRYLFKLHQLLTDHKSELARLITLENGKSLSESLGE
                     VQRGIENVEHAAGITNLMMGDSLSTAATDIEITNYRYPIGVIGGITPFNFPMMVPFWI
                     FPMALAAGNTVVLKPSEKTPLLMEKIVELVEKAGFPSGVFNVVYGAHDVVNTLLQDPL
                     VKGISFVGSKNVGEYVYREGTKNLKRVQALTGAKNHVVVLKDANIDRAVKDLIGGAFG
                     SAGERCMAASVIVLEEEIADQFVEKFKAAAKAIKIGNGLDEGVFLGPVIRKDAQQRTF
                     DYIQKGVDEGAKLVLDGRENIPEKGYFVGPTIFDNVTMDMKIWQDEIFAPVASIVRVK
                     DLMAAVELTNESEFANGSCLYTNNASAIRYFRENVDAGMLGVNLGVPAPMAWFAFSGW
                     KHSFFGDLHANGKDSVEFYTHRKVVTARYAQSEI"
BASE COUNT         7946 a         5295 c         3975 g         8681 t
ORIGIN      
        1 aaataagtaa tctaaccgac tgttaactaa accattgcag gtcccgttaa agatacttgt
       61 gcctgttgtc accgcttctt tttcttgtcc acaagcgctt aacacactta ataaagcccc
      121 tgctattatt aataataata tctttttctt attaaaaacc tcctcatcta tttccagatt
      181 agtaaatgta gtaatctttg ctttcttttt tctcaatact aataactaac ttatggggta
      241 aacaaatact cgtttgaccg ggttttgaga tccatccagt tctaaccgcg atttgatcag
      301 gactattatc ttctttaact cgaattcttc catctttaat ctcaacaata ttatattgtc
      361 ccttcgcagg atgataattc acgagtttat gattgatctt atccaaatcg aagcgatcca
      421 tttccttgcc atcaatttga acgatggcat atttgatagc atcttcagtt gtttcattct
      481 ccttttctat agagaataca aataagggaa taaaagaggg aataatcaaa atgccaataa
      541 ttatgacatc gcctatcttg acaccagctt ttcttaaaaa tttcattaac gatatctggc
      601 taaacatatt agaatttttc catggaaatg gtgaaatttt tcggaaatta tctgcattaa
      661 gagaatcagt taaacaaccc tcaagttgtt ccttaataca ttgttgatcc atcttcatac
      721 caataaaaac tagtttatta atgcgttcac caaacaacgg atgccaggct tccttcaatt
      781 cgggtttttt tgtataatca tttgacactc aattttaggt aaactagcta cccaataatt
      841 taatgattca atacttttat ggctacccga tgtttcaaag atcgtcgaaa aatcactatg
      901 ttgggcaaac caaagaaacc cttttgctct tgtaatattg ccaggaaaat ttttatccgt
      961 aagatgggca aatttttgtg cgtcaaggag taaccgattt cgatagataa aacttgagat
     1021 accatattct tctgtttcag gaatatgatt ttgatagcca agctctaact ctttgaacca
     1081 gcccattgaa taggaagtct catctatatt aaaaagattt gtatttagaa ttttcgataa
     1141 gtctacttca cctttaattg tcctaattat tttggcattg gactgtaact tagcaattag
     1201 accgttaatt ttgtaaatcg tcttggttga cactaagtca ctattattta aaagtaatat
     1261 gttacaacac tcgaattgat caattaacaa gccacgaata tcctgttctt cttcaactac
     1321 attaccttca gcttttcttt cctgaatctt ttcacccgtt tcgaaattat cccaaaaacg
     1381 ttttacatcc actactataa taatggcacc aatctctaat cgttgggtca aatcaatgtc
     1441 taaagggttt ttagctaata taattgcttg aataattgga attggtttgc tgattcctga
     1501 agcttcaata acaatttgat tcaagtcaga aaattgcact aattgatcta gttcaacaat
     1561 caaatcttcg cgtaatgtac aacaaatgca tccattcggc atcgaaacaa gtttttctcc
     1621 agttctttta aaacctttct tgtcgactaa taccccatca acatttactt cccctatgtc
     1681 atttacaatg acagcaattt cctttccgtg atcaccgtac agaatatgat ttagaagtat
     1741 cgtttttcct gaaccaagat agccagttaa gattgtaata ggtatttttt catagggaac
     1801 ctctttctat accttgaatt tacactttaa gtgcaacaca taaaaatgag tcataatcga
     1861 tatccaacta gtataagttt gtcgagaaca ctcctagaag gaaaataatt atgagccagt
     1921 attgtcatct tactatactc aaacgagaaa gaatctttct gcttcacgaa gaaggatttt
     1981 ctattagtat aattggcaac gacattcagc atagcccgtt tactatttta catgaactga
     2041 gaagaaacaa gaaaaaaact aatcaccttc caaagcggaa aaaaattatg cttatcgaag
     2101 aaaaaaatgc ggacgttatc acattctaaa tgatccgtga gtttggtcaa ttgttcgtca
     2161 tttatttgtc gattttcagt ggtcgccaga gaaaatctcg aatcgtttga agcatgaaca
     2221 tatggacttt tcaattagtt ttatcacgat ctaccgtgca atttgcaatg atcttttcga
     2281 tacagaaccc ctctcacacg gcaataaagg cctgatccgt tcattgcacc atcgaggaaa
     2341 aacaagacat acaaaaaatc atgtcgagtc tcgtgggaag atttgcctta ctcattcgat
     2401 ccatggccat ccaaaatccg cagatgatag aagtgatttt ggtcattgga aagccgatat
     2461 tgtagctggc aaaactagtg gtacttgttt agtgactttg acagacagaa aatcatgctt
     2521 ccttttagca ggaaagaagg tccccagaaa gaaagccgct tatgtgagcg agaaaatgat
     2581 tgaactttta agcagtattc caaatgaggc ggtcaaaacg atcactccag atagaggaaa
     2641 agaattctcc aatcatttcg cagttacaga agtattgaat aatatgccct tttattttcc
     2701 agatcctcat gcccttggca acaatgaaca aattaaaata cgaatagact cattcgagaa
     2761 tacttgccaa aatcgaaaga gatagctacg gtagataact caacgataaa tcagatgatt
     2821 gaaaaactga ataacagacc tagaaagtgt ttagattgga gaacacctta tgaagtcttc
     2881 tttgataaag tgttgcgctt gatttgacaa ttcaagaaat aataaaaagc agatcaaatc
     2941 caaataaggg aaaaatgatc tactctggta ttatcaatta attggccaag ctattatgcc
     3001 gttttgctaa acgtctactt cttccagtat tgaccttgat aaaacaacaa tcaggatccc
     3061 gttttaatac tctatgaact gtgtcaatac taacatgtaa agttgcagca atatcagcta
     3121 atgtactccc atttaatctc atttgctttg caaattgata acgccgataa gcatcaatat
     3181 tcttggaatc catagacaat aatacttttc ttaccatgta tttcctccaa agattggatt
     3241 ttaatgggcc atcatttctt gagcaatctc atgctcagat aatgaagctg gatagaaagt
     3301 aggccaatta tgcatttcat tataaagttt ttcttgactt tctccaccaa agaaaatatg
     3361 gaaatgctct gccttacttg gtgcaattcc atgatcgcta aattgaatat atttaaaacg
     3421 accagcacct gcatcatcag tttcaaaatt aaaacgaaca ccacggtttc ctttttcata
     3481 attcaaaatt ttgtatccaa catatttgta tgtgtattga tgatgttcac cgttgactac
     3541 aaaatcaatg gtgttgtctt taatgttgat agtatcaata tctgtcttat agccagtagt
     3601 ataataatct ttgtactcgg cagctgtcat gtctttattg agttttgctt tgtaatcgaa
     3661 aacttcatcc aaaattccat cttttaacaa cggataaaca gattgccatt cgcctgtata
     3721 atcactcaat tcgcgatcct tcacatcggc atctttaaag tacccattag caactgtctt
     3781 ttcatccttc gcttcttttt ctggaactac ctcttcacca gcaaccatag ttgttttctc
     3841 taacgctttt agattgtctt ccattactga aacataatct tcaccattat ccatttgttc
     3901 ttttgtaaga ctttcaagag gattcaatac ttccaatttt atcccagctt cattggccaa
     3961 agtttttgcg attttatcat tagcattctt ttcaaagtaa atataattga tcttattttt
     4021 tttaacatac tcttttaatt cagctaatcg accagaagat ggctcttctt caggacttag
     4081 tccagcaata ggaacttgta tcaatccata atccaaagct aaatatccaa aggctgcatg
     4141 ttgtgtcaca aaactttttt gtttcgcttc tttaagacta gtggtatagt cagcatccaa
     4201 ccgtttcagt ttagtcaaat acttttcagc atttgtctca aatacttttg cttttttcgg
     4261 atacaattta actaactgat ccttgatatt tgaaacttcc ttaattgcca ttttgggtga
     4321 aacccacgta tgaggatcta gttcatgatg gtgatcttct tctccgtgat catgatcttc
     4381 ttcttcacta cctggcaata aaatcatgtc ttttgttcct tctactacat taggcccagc
     4441 tttcttccaa ctttctttag cttttggtac ccatgattcc atgttttcgt tatgatatac
     4501 aaaaacatca gcatcatgag cttttgccat atccttagct gagggctcat agtcatgagg
     4561 ttctgatccc gctggaacca ttaaatccac gttcgcttca tcgccgacga tgtttttggt
     4621 gaaatcatac attggataga atgttgttac aatttctaat tttccatctt tatcattcga
     4681 tacttttgca tcattagtgc tggagcaagc tcccaataat cctagagctg ctatcccaat
     4741 aagtcctaca ctgattttct tcattctttt tccttcctta attatgctaa tttcttcatt
     4801 ttattttgtt tatgttcttt gataattttt aatgcccttt ttctagtttt gatattcggg
     4861 cttttaagtc gtcgatatgc actagatata tccgttttct ccattagaaa ttacccctaa
     4921 tcaatactta tcattatttg ctttccgcca gtaatttatc aaaactctgt ttgatccttt
     4981 cttcatccaa catttttcca attagaataa tagtggtttg gtctttttgt cgagtggtgt
     5041 attgaaaatt aacctgttcg tttacccctt gtatggcaac tataaaatct tgatcttgca
     5101 aagcaatcaa tcctttaaaa cgatacaggc tcccttggtt ggttaaaatc agccggtcaa
     5161 ttaattggaa taaaaaatct ttttttatgt cttgatctga agttaagaga attgatttaa
     5221 actcatgttc ttgatgatgt tgatgatagt gtttgccatt atagtgattt tctgatgaat
     5281 cactttcaaa aactaaggga tgattgaatt tttccaaatt ataaaaatcc tttttttgaa
     5341 tcgtttcact atgtgtgaac attcgaatat cggataaagg gttaatactt ttgatttctc
     5401 tctgtaattt ttttagtgca gataaattca agttttgttt tctagacaca aaaatgcgat
     5461 ctgctatgac aagttgctta agggcttgtg gttctctttc aataagttca aaactgtcac
     5521 tatcaataac agtcaataaa ctatcgatat atactcttcc tcttagttga ggcgctgtta
     5581 aaagtgtttg aatgattggt tggggatctg ctatacctgt agtttcaatg atgatttgtg
     5641 aaattggttg ttgatgttct tctattgttt ccagtaaaga aatcaatatt gctaataaat
     5701 cactgcgaag actgcaacac atacatccat tatttagttg taacacccgt tcctcgctat
     5761 gaactaataa tttgtgatca atcccaactt caccaaactc attttcaatt ataataattt
     5821 cttccctggg gtagggtgag acttgcaagg cttgattgat tagcgttgtt tttccagccc
     5881 ctaaaaaccc agaaacgatt gtaactggta tgcccatttt gtcacctttt taccacttag
     5941 ctatttcact tctttgaaaa ttgcccgtct gcgcaatttt ggcgaatact tttttaattc
     6001 taaccgttca gggttattcc gtttattttt gctggtgaga tacagacgtt ctccagtttc
     6061 gacacattcc aaaataatat tttgacgcat aaatcttcct ccttcaatac ttatcgatct
     6121 tcaagatatg cttgaatttg ttgtgcatct tcaaaagtta actcgccaga ttccaattgt
     6181 gaaactaaat tttctttcat atcaacaggt atctcccaat aaccatcaat acattgaaat
     6241 aactcctcgt catactcttc aaaaattgga tagattctta aaaaatcatc aaatgataag
     6301 ccttggtcct catagtaatc tttgactaat ccattttcaa ttgcctgttg ggtcggtaaa
     6361 cccgtttcag taataattcc tctctctacc atcgaacgat aaaaagtgca tttatctagc
     6421 gattgctggg tcgtttcaag ataatacttt aatccttctt caactaaagg tgggtaaata
     6481 atttccattt tgattccctc ctaaaagtta tatattaaac tattttgaag ctcctttaat
     6541 tactttcttt ccattatagt acccttttaa agatacatga tggctacgtc tataatcacc
     6601 attcgcttcg tcaaatgaaa tttctggttt tactacagtt tgatgagttc ttcttaaccg
     6661 tttcttcgcc ttagatgttt ttcttgctgg tactgccatg atatttcctc cttttaccaa
     6721 cttgcttttt ttactccagg aatcaaccct tgatgggcaa gttctctaaa cttaatacgg
     6781 gacataccga actttcgcat ataccctctt ggacgaccat ccgtctgatc acgaagcctc
     6841 agacgattcg gatttgaatc tcttggcaat ttagcgagag cggtgcgatc tcctgcggct
     6901 tttaattcct gacgtttatc tgcgtacttt tcaatcatcg ccatttgttt ctttgcttta
     6961 gcaattttcg acttttttgc catatacctt tatactcctt ttattttgat ttagacatct
     7021 caaatcgtaa tcgttacgtt ttgacactga tactttacca acaagagttg ctcttgtcaa
     7081 caataaataa catgaaataa aactcatatg aatagataac tatttgaaaa cgaatttatc
     7141 ggtacataga gataatcaaa tcatttaaaa gaatatgcag tttaagctct gaaaaataag
     7201 aattcacttt tattagtcca atcaaacaca aataccgttt taagtagctt ttcctctact
     7261 taaaacggca atatgaaaga aactataact ttttattcaa tcttttatgt ttaactggtt
     7321 tatcgccaat tttttaaaac tttgattatt ccttatatta taagaataga cattaagtga
     7381 actaattcaa tcatactgat tctttcgtgt attcaaaatt agatgctgtt taataaaatt
     7441 attctttttg aaaaagaatt ataactatat cccaaaaatt gtaggttaat ttaaagccta
     7501 tttcatcatc gtgattgagc ttctttttca tagacgaatt tctcagatag tttagttttc
     7561 tttatgagat ttttgtatat ttctgacctt cgatacaact cactatgagt accttgatca
     7621 actatttttc cttgatccat cactacaatt ttatttacct tttcaataga cttcaagcga
     7681 tgcgatataa ttagtactgt cttatcttgt attaaacgat ttaaactttc ctgaatacgt
     7741 ttttcatttt ccgcatctaa actggcagta atttcatcta aaattaaaat tggcgcattt
     7801 ttcaaaaaag cccgtgctat ggataggcgt tgtcgctctc ctccagaaag tgaacttccg
     7861 ttttctccga ccaatgtatg ataaccgtca ggtagttttt caataaagtc ttcgcagtta
     7921 gctaaacgag ctgctttttt cacttcctca tctgacgctt gactatttcc aatacgtata
     7981 ttttccaaaa tacttgtatt aaacaaagtt acctcttgaa aaacaatagc gattttgcta
     8041 aacaaagaag ctggagatac acgtttaata tcatacccat caattaaaat acagccttca
     8101 tcataatcat acagtctaga cactaatttc aagatactag ttttcccgga accactagca
     8161 cctactaacg cagtcacttc tccttgttta gccgtaaaag agatatgatc taaaattggg
     8221 gtattgttat catatgagaa agagacatct cgcaactcaa tgtcaaaaga tttcagagga
     8281 ctatctgatc cctcttggat actggtttcc ttcatagctc taattcgctg tattttagga
     8341 gctaaataaa atatttcaag cactgcttct ttcatagaat cgaaggaatc ctttattttt
     8401 attgcggcta gtaagtaacc aacgacgtag agtatagtca cttcacccgt taacagtaag
     8461 tgaacaccta ctagaatgac tactgctaaa ctaacatatg agaaaataga ggataaggcc
     8521 atgactgaaa aagtacttaa ttctaccttt aaatgaatcc tttcactctc ttccattttt
     8581 ttgaaaagtc tgtcttgaac ttttttagat agattaaagc tattaatctc ttgctgcaat
     8641 tctatagttt cttgaaattc ttccgagttt tctctcaaag tatcgtaata tttagtattg
     8701 gctttcgttt gggatttctt tgataacaag attaagacaa aactaaataa cgttggcaaa
     8761 ataacagcta atcccatttt gacattacca accaaaagca tcactgaaat aaaagggaaa
     8821 aacagagcca taccgccggc tttaggtatt gcatgactca tcgcatgctc aataccttca
     8881 acgtcagaca tgatagtttg agataaatct gataaattat gttttgaaaa ataggataat
     8941 ggtaaatttg acaaatcgtc tgcaatttgc attcttaaat gcgcactttc tttataagta
     9001 ctattatata agttttcata ctccctatct aacaaccaat acatgaaaag caaagtaacg
     9061 aacgatactg taaaataaag ccaaggcggc tttacatttt ctaaaactaa ttcgtctatc
     9121 agcatcatta taatgaatgc tggtaccata ttaatgcagt atacaaaaaa gctagaaata
     9181 gatgctttaa ccaaatcttc tgcgccctga ttagttaaag cgaatttgtt tttataaaaa
     9241 cttttcattg tcaagcctcc aatcatttgc attctcataa ttagtgacca attgtttata
     9301 cacttgatgt ttagccatta attcattatg atttccacgt tctactattt tcccttctga
     9361 caagacaaga atttcatcta cagatttaat gctggataat cgatgagcta tcataataac
     9421 tgttttttct ttcatcagat gttgaaaagc cttttgtagt tcatactcat tatctggatc
     9481 aatagatgca ctggcttcat ccataataac aatctttgca tcttttaaaa ttgctctggc
     9541 aatagctata cgttgttttt ctcctcctga cagataaact cctttactac caattaaggt
     9601 atgctctctt tcgggaaatt tttctaaaat cgattcgcaa ccggctaatc ttagcgcgtc
     9661 aaatacttta cttgctggcg cttgaggatt tgctatagaa acgttatcgt aaatactctg
     9721 attgaatagt ttcgtatctt gaaagacaaa agcaattgtg ttaataattg tgtcttttga
     9781 atagtgattt aaaggcttac caccaatttt aatctgtccc ttatccacat tgtagaaacc
     9841 tgaaattagt ttagctatcg tactctttcc gcttcctgat tttcctacta atgcataaat
     9901 tcttttttgt tctaaaacta agttgaaatt ttctaaaaca cactcttctt tgtatgaaaa
     9961 gctgacattt tcaaatgcaa tgtcacaatt tttaatctgt gtctcgttcc catattttag
    10021 ttggtcttgc ttcatttcta aataaaggga gtctagtgtt tcgactgcat atcttgcttc
    10081 aaacaagtgc atacttacat acattattct catgaaagaa acaaaaataa ttccacttaa
    10141 aaaaaacaac atcaacaagt caacagctaa tatcttggga gtggtaagag aagttataaa
    10201 aaaggttata ggaactatca aaatgcaaac tatgccaaaa aatagccatt gaaaaagaac
    10261 aaaaggtgtt ttcccactca aagaatactt atatgcaaac ttagcataat cgttaattgc
    10321 tttattcaag gctttaaatg atgttacttt agcaccaaat atctttataa cttgaattcc
    10381 tcggatatat tctaccgttt cagagcttaa cacatctaac gattcttgat atttttgaat
    10441 aaaatttgta ttctctgtca ttttctttaa caagaataca ccaattacta acatggcgat
    10501 tagaaccaat ccaattttaa aattaatgaa aaagcctaag gcaactgata aaacaggtgt
    10561 tactatggct tgagcactat ctggaatcaa gtgagcaatt gccatatgtg ttttagccgc
    10621 gttgtcatca attgtctttc gaatatatcc cgaagaattt aaatcaaaaa aacgaaaact
    10681 tgcttctgtt aaaccgctaa ttcccttttt tctcaaatta gtctctaagc gaaacccaag
    10741 gatatgagaa aataagccag aaaaaatata aaataaagct cctaaagtta accaagcaac
    10801 agtttgaacc gcataactct tagctaaata ttcatctcct acaataatta gagacttaag
    10861 aaatttgtaa atactgtaat atccatagac tgttaatacg acagaaaaat cagaaaataa
    10921 agtggctaac catccgtagt atttcatttt agggacataa ctaaataatt ttttgtatac
    10981 tttcattttt tcctcccccg cattcaattt cttctcttat tcgtttacaa ctgttaatgc
    11041 tttccgtaat agcgtaaatt agagatgtac aaacagatag aaggtaaact acgttctatt
    11101 ttttgtattt ttttaagact tttcttccaa tcaatacacc aatcatagat aaacttgcta
    11161 caactaacac tgaaatgatt ccccatatac ctaccgcata gtggatcatt gcatccattg
    11221 ttgcagcaga ttgtccttta tctatccaat cttgacgaaa acgatctgta aagaaccata
    11281 taggaatcca ctgtccggca gcactgccta attgcattag agcccaagac gcaacttgag
    11341 gaattgctcg atcatatcca aatacagata gaataatatc agctaagatc gccatactaa
    11401 tcgaactgat aaaccaaggt aagtacgccc cgcccattaa cgtaaaaaat aacaataaaa
    11461 caattgtgta aatagtaaaa attccttttc tagggtagtt atagctaata taaacaaata
    11521 tgattccaga taataatcca aaaatccctg gggatatgct gtgaccaaac gccccaccaa
    11581 tactactaac cattattgaa aaaaagtaaa ttactaggga aataactgta gctaaaccaa
    11641 taaaaatata atcttttgtt ttcatatata ttctcctcaa ttctatttcg ttatgtcatt
    11701 aaaaatctgt tctatcaaag ttgaatcttc tactctaagt tttatatctt tttttattcc
    11761 accatttttt aaataaataa ttctattgca tgttttataa agaaattccg gatcatgagt
    11821 ggctataact actgcaccct tttcttttaa gtctttaata aggtcagcaa tcctttccat
    11881 attaatataa tccaacccac ttgtaggttc atcaaataga aataaattag tttttgacaa
    11941 tgaagctata gaaaccaata atctttgttt ttctccaccg gataaatcaa acggtaattg
    12001 atctttcatt ttataaagtt ccattttttt taaaattttt tcttgctgat ctttactaac
    12061 tatttcattc cccagggcta actcgctcct cactgattct gtgaaaaatt ggtaatccat
    12121 ttcttgcatt actaaaaacg gcgatgacaa atttttttta ttttcgatta tctttccttt
    12181 ggtagggcga ataatcttca tgagtattct tagtaaggtt gttttcccca caccgttttt
    12241 ccctaccaaa ccaataacat ctccaacttt gacatcaaaa tttatgtctt ttagaatatt
    12301 ttcataagta atttcttcaa cttttaatac atctgcactt accttttcga tatagggaac
    12361 ttcaatcgaa ctattaaaaa tgtcaaattt ccttaatgcg ttattgtttt cagtttttaa
    12421 caactgaata gttgtagttt ttacagttct atttttaaca aatagaactt gatcaattaa
    12481 ttctttcaaa tagtaaaaac gatgttcagc tataacaata gtaaatcctt tattttttaa
    12541 atcacaaagt aagtcagcaa gtttcttagt cgctttgaag tccaaatttg aagacggttc
    12601 atccaatata attaatttag agtttagcga taaactacat ccaatagaaa ttttctgccg
    12661 ttcaccactt gatagcgaaa aaatgttttt atctaatata tttgaaagat ctaataattc
    12721 agctaattca ttgattcttt tatccatatg ctcttttgta aatccaaagt tttccatcga
    12781 aaatactaac tcactcgttg tatttgttgt aaagaattgt cctctaggat cttgacttac
    12841 gtagccaata ttttttgata tactttcttg tgttaaggat tgtagcgagt tattttcaaa
    12901 taaaatttcc ccaaccaatt ttccgtcata aagtcttgga ataagtccat tcattaactt
    12961 taatagtgtg gatttcccac tcccagaaga accagtaatc aatgtaagac tacctttttt
    13021 tattgaaaaa ttaaggtcaa caagcgcttg ttccttaaca tccttatatg aaaaagaaac
    13081 attgttaaat tcaaacaatt ctttcacctc aaatcaaaat acttaagaaa aaaatagtaa
    13141 cggaaaacag gatgatatag tctaataagc tcatgtttgt tttatagtaa gaacttcttt
    13201 tcacaggaga ttctatcccc tttgttattg cattagcggt catttcttca gcaatcatag
    13261 ttgcacgtat aagaacggga actaacagaa attccaaata ttgcagaggc tgaaaaaaag
    13321 acaagcgaat gtttctcatt tttaaagatt ctttaatcat tcttatttca gaacgataag
    13381 tcggaaagaa tctgatcact actgtaatac ttaacattat ttttttcggt aaatgtattt
    13441 tttctaaaga ggataataat tcattgctag tatagacact aaccaacaac catgagatca
    13501 ttacgaccgg caacattcga aatacaatat ataaggatgt cccaaaaaat atagtaaaaa
    13561 actctatctt gatagcatca ataattttca ttactaaaaa cagaactgaa taaatcaaga
    13621 tgaaataaat acatgtcttt attttacgaa acatcaatac taaaactgta gcaataatga
    13681 aacaccccac ttgaaatata tttccctttc ctaaaaaaat aatgaccgga aaaaaaatat
    13741 ttaaagtaat caaggttaac ggattgattt ttgacactct ttcacctcca aaaaataaga
    13801 tcgcactgtt atcttaagct gataaaaatg caccgttatt cagataacag tgcgatctta
    13861 tcaaaaagca taactgagaa caattctcaa tgcaagcttt tttttaatta actcagtaat
    13921 tcaatccacc caggaacaga aaattgatac aatcttctgg ttaatagcat agtcttttct
    13981 tttgaatagc tatgcttcaa tatatcatag aatgtagcgt agaatgagta aatgtagaag
    14041 tggatttctt cttcattaaa gactaaattt tgattgatca ttccgatagt ctttaactta
    14101 tctagacaac agactgtctt ttttgtcaca aatgatgtaa ttttttcaac aatatcttga
    14161 tatttggttc cagctgattg gaataaaacc aaatcgaata tacgtttatt ctcaaaaata
    14221 taattaataa atggatctaa ttcattgaag ttctctctcc aacttttctc tatatctata
    14281 ttttctaagt ttaagaggta tttggtaaac tcttcattat acatattaat aagcgcatta
    14341 atatgcggct gaataatttc ttcaaataac gcttccttag aagtaaaatg tttataaaaa
    14401 gcacccgtag ttacgcctgc ggtcaagcac agttgcctta tcttagtttg ctgaaatcct
    14461 actttttcaa aatggcttag tccactttct attaattttt ggtgagttgt aatataatct
    14521 ctggtttcta tgggtacttc ctcctaataa gatgaattaa ctatattatc ttacacagga
    14581 cttgaagttt caatcgttaa cgtctattac tgaactcatt ccttagagct aaactaatga
    14641 gaaagagcaa aataactgat acaaaaagca atcctacaag aattaataga ctcatctaaa
    14701 tcattcacct tttctaaaat aatccgagaa agatttaaaa aaattatatc cagctattag
    14761 gataagtcct atcataatca ctccaatagc cattttctta tcctccctaa aaataaagcc
    14821 ttttacttaa aacctttttt tgtaatcgtc aataaatttt ttccctttat cagttaattg
    14881 aaatcctata tctaaatagt cctcatatct aagtttagtc agcatctcac ttacagatgc
    14941 tggactaaca cttagaactt ttgctaaatc attatttttt aatttctttt ttctttttga
    15001 taattcctga attgctagta aataaattag tatagtagtt gttttaattt gtaccatacc
    15061 taccctccaa attatttcga aaggccttca gcaattttat ccaggttcca tttcatcatc
    15121 gcatagtaac tatcaccatc ttgtcctttt tctgcaattg aatcagtaaa aatcgttgaa
    15181 tagataggaa tattggtatc ttttgatact gttttcattg gtctatcgtc cacactgctt
    15241 tctacgaata aggagggaac ttttgttgtg cgtaattttt caactaagtg ttttatttga
    15301 tctggtgttc cttcttcttc agtgttgatt tcccaaatgt aagcagaagg cacattatac
    15361 gctttcgaga aatatttaaa gcatccttca cttgtaacaa tcattttttt atcattcgga
    15421 attgaagcaa atttagattt agcttctttg tctagagaat ccaatttttc aatatactta
    15481 tctagatttt ctttatagaa ttttttatta tcaggatctt tttccgctaa ctgtttttca
    15541 atatttttag cgtaaataat accgttttct aaatttaacc aagcatgggg atcttccttc
    15601 cctttctcac tctgaccctc taagtaaata acatctatgc catcacttgc tgcaaaatag
    15661 tctttgtttt cctctttgtt cgcatttttt actaattttg taaaccaagc atttcctcca
    15721 gtttccaagt taacaccgtt ataaaaaatc aaatctgctt ttgaagtttt ttgaacatct
    15781 tcaggcaaag gttcatattc gtggggatct ttcccaatag gtacgatact gtgtaaatca
    15841 attttatctt ttgctatatt ttcagtaata tctgctaaaa tcgaattagt aactactacc
    15901 tttaattttt cgttcgaagc cactgtatct ttgtctttac tatttgttga acatgccccg
    15961 aatataaaaa gagcaatcaa aatccccaga cttcccagta ctgctttcca ttttctcatc
    16021 ataactttct ctccttcttt cttaaaaatt tttgttttgg tgagattaga aaactaatta
    16081 caaataagaa tgccgctgtt aaaacaatac ttgatcctgc tgctatgtta aaactataac
    16141 caatgaacaa acctagcaat gatgagcacg ctccgactgt cgccgaaata aatatcatag
    16201 tttttaaact gtttgcatat aaatatgctg tagcagctgg tgtaattaac attgcaacaa
    16261 ttaatatagt tcccacactt tgcatagctg ttactgctac taaagttaat agaatcatta
    16321 atagataatg ataaaaactg acattcatcc ccattgcttt tgccattaat ggatcaaaag
    16381 aagtgattaa taattcttta aaaaatagaa caactgtaac caacactaaa acagaaacgc
    16441 caattgtaat ccacttatca atatcttgta cagctaaaat atttccaaat aagatatgaa
    16501 ataaatccgt tgagctattt gcaactccta taaggataac tcctaatgct aaaaaagaac
    16561 tgaaagtaat accaattgct gtatctcctt ttattacact attgcttttt ataaaagtaa
    16621 taatgataga agctaataga ccaaatacaa tcgcaccaat aaaaaaatta atacctaaaa
    16681 tataagaaat tgctactcct ggcaaaacag catgagaaat agcatcaccc ataagagaca
    16741 ttcctcttaa aataataaaa caacctactg ttccagaaac aatccctata actacagatg
    16801 taattagagc attctgtaaa aagtgaaagt catacagacc attaataaaa ttttgaagca
    16861 tattattccc cttgtatatt agagttaggg ttttaacctt ccggttttga ttggataacc
    16921 ctatgaacca tcgttatttt aatttggtat taactcattt cttttgagat aatatattta
    16981 ttggattgag aggctaagcc gttcccccct ctccaataaa tatagtatct ccataggctt
    17041 tttttaaatt ctcttcatta aatacagatt ctacacttcc gtgagcaatt agatttcgat
    17101 tcaaaagaat aatattatca aaatacttct ttaccttgct taaatcatga tgcacaatta
    17161 gcactgtttt tccctgatgt ttcaattctt ttaacgtatc cataattatt cgttcactaa
    17221 ctaagtctat ccctacaaat ggttcatcta aaaatatgaa atccgcattt tgagcaagac
    17281 atcttgctaa aagtacacgt tgaaattgtc ctccagataa ttctcctatt tgatgattag
    17341 aatattttcc catatcgacc ttttccaaag cctttgaaac tctttgccat tctgcatttt
    17401 taattctttg aaaaactttc attccggcat atgttcccat agatacacat tcttttactt
    17461 ttattggaaa agtaaaatca atatcagctt tttgctctac atatgcaatc ttcaccagtt
    17521 ttttattgat atcttcatta ttaatggaga cctctccctg atgagggata atatttaaca
    17581 ttgctttaag caatgtagat tttccagcac catttggacc aataatacct gttaaagcac
    17641 cttcttgtat ttttaaagaa atctcgttca atgctaaaaa atcgttataa caaacattaa
    17701 gctttttcac ttctaacata actttctcct tctaaatgat aatgattatc acgatcatat
    17761 ggtatacaaa aattatattt tagtcaaccc taaattttat aatttagatt tttttctgtt
    17821 gttgaagatt aggatgtcaa aattatttga aactactcgt atagtaaata gtaagtaatt
    17881 ttcaaaacac gaagaaaaac aaaaagaaaa aaggaaacgc cgaagcattt cctttcagtg
    17941 atttaatgag aacaacacga tttgacttag agtctcaaaa agtcgaatag gtacactcat
    18001 ttaagtgtct ccattcgact ttttggggat gagctggcta ttgaggtccg cttaccctat
    18061 tgaataaata caagattggg tatttctaat aagtccgccc ttcatattgg ggtgatcggg
    18121 gcgaacatgc catcttttca tataccacct cctcgacact caataatcaa agattctcgt
    18181 taatcttctt cgatgcttgc aatgatgttt tcaatattca tataacgaaa atcttcttgt
    18241 ttgatataaa cgatctgagc ggtacatttt tcctttttga tgatttcttt tactttttcc
    18301 tcagaacgtg cgacctgcgg cgttaaaagt aaaacgtcat agtctttata attcagtttt
    18361 tcttcaacgt ttcggatcgt tgcataatct atctcatacg atagattttt ggctctgatc
    18421 gtttcaagca tttttgatac gagcagcgac gcactgattc cggtctcgca aataatcaat
    18481 agatccttat gcataatacc ctcctgtttt tagcctgcaa agccaattgg tgaaaatgcc
    18541 acataagtta aaataacaat gactaccaat gctatagcag tcaccttggt gtatttccaa
    18601 ggctcgatat cgacctttgt atcgaatgag ttcaacacaa attctccatc aggtttcaat
    18661 ttggaaacca ccatcaaaat gataatgtcc agaacgaata atgccgtcaa aacataaagg
    18721 aaatggatat tttggaaaag catttttgat agtgcataca agacgatatg cacggcaatc
    18781 gtcgtttttg ccccaaaagc agttgctttt tttgaataaa aggcaaagag aatgatcacg
    18841 agcagcggca tgttgtatag tccattgaat tcttgaacga actgatacaa tccagccggt
    18901 gcaaaagaaa tgaatggcgc tacgataatg gagataatcc ccacaacgac cgttactgtt
    18961 ttaccagcac gagcgatttg cttatcattt gctttcttat tgataagcgg tttataaaaa
    19021 tccagtgaaa acaaggtcga tgtcgcgttc aaagctcccg caaatgatga taagatcgcg
    19081 ccaaagataa cagcggcgaa aataccaaag atcattttag gcaatacttc actgactaaa
    19141 aaaggatacg cgttatctgg atttgacatt aaactatcgc caaaaatatt gcgagcgacg
    19201 atccctggaa agacaaggaa taacgcacct aagattttga agacgccgac taggaaagcg
    19261 cccttttgtg cctcagctaa attcttgccg gacaatgctt tttggacgat catttgattg
    19321 gtacaccaga aatacagatt gttaaacagc atccctgtaa atagtgtcgg ccatggaaca
    19381 acagccgagt cgatcgatcc cacagagtta agcagccatg gcgtgtttac cacaacgtgt
    19441 tcgatcccgc caacaaagct gccgtcacca agcttcatta agcctaaaat tgggaccagc
    19501 agaccacaag ccagcagacc gactccataa atggagtcac tattggcact taacgacaag
    19561 ccgccgatca gcagatagag gatgccgaca ataccaattg ccatcgctac aattatgatc
    19621 gcgacgatcg gctggacgcc cagcagctca tcaatatgga agatcttatt gaacaccagc
    19681 gatccagaat aaagaaccac gggtaagaaa gaagtcatat aggtcacaat aaataagatc
    19741 gaaataattc gtttggtaac cgtatcataa cgaatctcga tgaaatctga gattgtattg
    19801 atgccgtatt taaaatattt tggcaagaat atcacagcca aagctacgat cgcaatcgta
    19861 gcagttactt cccaggccat tacttccatc cctgcatgat aactttgacc attttgtccg
    19921 actatttgtt cggtggacag gttcgtcatg atgatcgtgc cggcgattgg caaagcagtt
    19981 aagctccgcc ctcccatgaa gaacccttct gatccagaag tatcgacact tctggatcta
    20041 gaataggcaa ataaccatac acagatgaca atcactagga aactgattat agaaaaaaga
    20101 ttcatcgtct agctcctttt caatagatta aagaccggtg acctctcgaa tgtagcttct
    20161 ggctttgact gcatattcaa atggattggc tttagccggg tcctgttctg cttcaactac
    20221 gatccagcct tcatagtcgc tggcatggat tgctgtccag attggagtga aatcaatcat
    20281 cccatcacca ggaaccgtga agacgccttt cttcacgccg tttaagaagc tgtctttttc
    20341 cttttctact tcttcagccg tttcttgacg aatatctttg aaatggatgt gtttgatacg
    20401 atcttgatga cggttgtaaa ccgcgattgg attttcacca gaaaagacca aatgtcccgt
    20461 atcgaacaat aatttaactt tgtctggatc agtcatttcc attaaacgat cgatttcttc
    20521 cgtcgtttga acgccggtac ccatgtgatg atggtaaacg atctccatat ccttttcgtg
    20581 ggccaaatcc cctaattttt ctaatccttc cgccagtttt ttccactctt catcagtgaa
    20641 aactggttta tcatcaaaga ctggcgctgt cataatccct tggatactat gaccctgctc
    20701 agctactacg atgactttag cgcccatcgc atgtaagaaa tcccgatgtg ctttgaaggc
    20761 ttcggcagtt tcttcaaaag gtttagttgt cagaaacgca ctgaaccatg cactggcaac
    20821 ctttaagccg cgaatattca aatattgttc caacacctct ggatcttttg gatatttgtt
    20881 gccaatctct gttccggtga acccagcaag ggccatttca ctgatacatt gttcaaaggt
    20941 attttcacta ccaagctcgg gcatatcatc attggtccac gcgattggtg cgatggctaa
    21001 ttgaatttgt ttggtcatat tctcacactc ctgcttattt ttttagttgt actaaactct
    21061 tcgtatcgaa tgattcttga caagccaacg cgatcttagt tgattgcaat ccatcttctg
    21121 cattaaccgc tggttgacgt ttttcttgaa tacatgagac aaattcttgg gcttcacgaa
    21181 tgaaggcttc tctgaatcgt tctgggaagt tttgtgaaca tggacggatg atcccttgat
    21241 cgttcatgat cgtcacaaga tttttctcag gcgcttgcgc tacccgcagc attcctttgg
    21301 ttcccatgat ctctgtttcg acatgatagc catgggctgc gtttctgccg gcaactagta
    21361 aagctattgt tttatcgctc aggctcatca ttgcggctcc agtttcaagc tcaccagcct
    21421 gatccaattc tggatacgcc gcatttttcc caatcgccca cacttgatcg acttcttggc
    21481 cggtaaacca gcgaaccaaa tcaatatcat ggatcgccat atctaagaac aagccgccgc
    21541 tgtcgttatt catggcaaat ttgacaaagc tttccaagcc ttcgctcgga tcgatcccat
    21601 aacaacgaat cagtgtgatt tcgccgattt cgccatcttc taccattttc ttcgcatact
    21661 gatacgactc atcatagcgg cgcatgaagc ctaacatgaa gacctgttca ggatgctctt
    21721 cgatgacttt ttgggtcttt ttaatatctt caacttcaag gcctaatggt ttttcagtaa
    21781 agacatgctt gccattttcc atcgccaagc ggacttggtc acagtgaaag cctgatggtg
    21841 aaacaataaa gactgcatcg atcacggaac ttttgaccat ttcttcatag ctggaaaaag
    21901 tatgcttgac gcctaatttc ttctgtgcga atgctaattc tgtttcaact aaactgcacg
    21961 cagccgtaag ctcacaacaa ctgacacctg ttgctaaatt ttgtgcatgt acttttccta
    22021 atcttcctaa accgacgatg cctactctaa tgttgttcat gaaatacctc cgttttctga
    22081 gaattactca ttgtatagtg ctggtcgttc atccatttga atcattactt ttgtttttgt
    22141 ttcacgagac tcatgacaag ccatcatggt gatcgctgct acatacccat cccaagcggt
    22201 aggaccgaca accgcatcat ttttgatcga atcgatccac agcttgaatt cataatcata
    22261 ggcatccaaa aagcgggtct gccaatctgg tgaaacaggt gtgtaatttt tttcttccga
    22321 tttaattcgt gtataggctg ggtccgtcat tcctacttct gccgtttcga aaaccacatc
    22381 acatttaata tcgtagccaa agcggcaatt cacaaagatt tccaaatcaa tcgttacacc
    22441 ggattttgtt tgaaagatca gcagctgcgg atcatgcaaa tcggcatggg agttgctggt
    22501 ttttttcggc aagatcattt gaacagattc ataatcttca tttagcaacc agcgaagcac
    22561 atcaatctca tgaatcgcgg tgttgctgat cgccatcggt gttgtgtagt tttcatctgc
    22621 gctaggattt ctatgggcac aatgcatcat taatgcttct ccgtattgct tcgattcgat
    22681 tgcttctttc agttcaatgt agccgcggtc atagcggcgc atgaagccaa cctgaaccaa
    22741 tttcttccca taagcaactt ccgcatcaac gatccggcgg cagcctgctg catccatcgc
    22801 taatggcttt tcgcagaaaa catatttccc atgcttgatt gcttctaaca catactgctc
    22861 atgggtcggg tcccaagaag tcacaacaac gacatccaca tcttcagaag cgatcaatgc
    22921 ttctccggtt tcaaagaatt tagcatcgac acgtttggca acctctttag cagcttttac
    22981 attgatatct gagactgctg tcacataagc cccttgtgtt ttctgattga tcctgtcgat
    23041 atgctcgatg ccgattgcac ctgttccgat aacgcctact tttactctca attacttatc
    23101 cccctgttct gttgtttaag cacacatagt atgcgcttac aaaattattc ctgtgtagct
    23161 tttattctta aaaggtagag ccctctcttt gctccgcctt ttactaccca taagcttgta
    23221 cgtataattc cttaatttga ctatgactag gcaccttttt attattttgc ggacttccgc
    23281 tggtcaacgc atccgcggcc attttgtcta aggctgccat aaacgcttgc tgatcaatac
    23341 cataatctcg aatcgttggg atcgacagct gctcacagag ctcttggatt tttttaatca
    23401 gataatccgc agcctcttcc agcgataaat cttcggctgc cggataaata aatctggcga
    23461 tcgtcgctaa ctcagtctga atagcatcct ttgagaattc aaaaaagacc ggcaataaca
    23521 tcgcatttga tatcccatga ggaatgtgaa aaagtgcccc caccggtcga ctcattccat
    23581 gaatcaatgt gactgacgca ttcgaaaagg caatccccgc ctccgttgaa gctaagctca
    23641 tttgttctct ggcttcagtg tcgtcgctat tttcatatgc ctgagaaagc gtgttcaaaa
    23701 ttttcttcat cgcttccagt gaaaatagtt gcgttacttc attggctttg actgaaacat
    23761 aagattccaa agcgtgacat agcgcatcga ctcccgttgc cgcggttact tttggtggta
    23821 cagttttcgt aaaatcagag tcaacgattg agatctgtgg catgaaaacg agatccttca
    23881 tcatcatttt gactgctgtt tttgtattgg taataactgc cacatcggtt acttccgaac
    23941 cagttccagc agttgttgac actgcaatca gcggaatgcc cgcttgcagc tgatcaaaat
    24001 ttcttgcatg aatcgcttcg agacttaatt gattagcagc caaaacggct accaccttgg
    24061 ctgtatccag acagctgccg ccaccaaaag caatgatatg atcacattga tgcttctgaa
    24121 aaagcttcag cgcatcataa acattttctt gcgtcggttc ggcttgaatg tctgtatact
    24181 ccgctaattg atcatctgtt tttcccaaca gctccttgat cttttgaaga tgcccggtct
    24241 gttccataac cgtatcacta atgattaacg gcttgttgcc tagttgttct gattcttcca
    24301 taagaaattg gattgttccg ccgccaattc ttaaattggc aggcattttc agttgaatat
    24361 tcacagaaaa aacctctctc tggcttatag cctataacag aatcctcgaa gctctttaac
    24421 agagcttcga agcaaatctt taaatctcac tttgcgcata acgtgctgta acaactttcc
    24481 gatgggtata aaactcaaca ctgtctttgc cattggcatg caaatcacca aagaaagagt
    24541 gcttccagcc tgaaaaggca aaccaagcca tcggtgcagg caccccaaga ttgaccccca
    24601 gcatcccagc atcaacattt tctctgaagt agcgaatcgc tgatgcgttg ttggtataca
    24661 gacacgaacc attcgcaaat tcagattcat tcgtcagctc aacggctgcc atcaaatctt
    24721 ttacccgcac gattgatgcg accggggcaa aaatctcatc ctgccagatc ttcatatcca
    24781 tcgtgacatt atcaaaaatc gttggtccaa caaaatagcc tttttctgga atgttttcgc
    24841 gaccatctag taccagtttc gctccttcat cgaccccttt ttggatatag tcaaaggtcc
    24901 gctgctgtgc atcttttcga atcactggtc ctaaaaagac cccttcgtcc aagccattgc
    24961 cgatcttgat cgcttttgcc gcagccttaa atttttcaac aaactgatcc gcgatttcct
    25021 cttccaaaac aatgacggag gctgccatgc agcgttcacc agcagaacca aaagctccgc
    25081 caataaggtc cttgactgcc cgatcaatat tggcatcttt cagcacaaca acatgatttt
    25141 tcgctccagt caacgcttgt acccgtttta gattttttgt tccttcacgg taaacgtatt
    25201 caccgacatt ttttgatcct acaaagctga tgccttttac cagtggatct tgcagcaatg
    25261 tgttgacaac atcgtgggca ccatagacaa cattaaaaac accgctagga aagcctgctt
    25321 tttcaaccag ctcaacaatt ttctccatca acaatggtgt tttttctgaa ggcttcagca
    25381 ccaccgtatt tcctgccgcc agagccatcg ggaagatcca gaagggcacc atcattggaa
    25441 aattaaacgg tgtgatccct ccgattactc cgattgggta acgataattc gtgatctcaa
    25501 tatcagtcgc cgctgttgat aaagaatctc ccatcattaa attggtgatt cccgctgcgt
    25561 gctccacatt ttcgattcct cgttgaactt ctcccagtga ctcggacaat gatttcccat
    25621 tttccagcgt gatcaaacgc gccaattcac ttttatgatc tgttaaaagc tgatgcagct
    25681 tgaacagata acgtccgcga acaggaacag gaactttttt ccaagtttga aacgcagcat
    25741 cggcagcttt aactgcttcg gctgtctctg ctttgctaga caacggtaca ttcgccagcg
    25801 cttcttctgt agccggattc attacttctt caaactctgt tgagcgacta gcgacccaac
    25861 gaccatcaat ataatttctt aaaaatcttg tcattta
//
LOCUS       DAMEEU010000039        25843 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.040, whole genome shotgun sequence.
ACCESSION   DAMEEU010000039 DAMEEU010000000
VERSION     DAMEEU010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25843)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25843)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25843
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.040"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..710
                     /locus_tag="PB779_001585"
     CDS             <1..710
                     /locus_tag="PB779_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HDE0739112.1"
                     /translation="LVKQSKRLFPEINCVVADAGYKTPKFVHFLTHLNLRPCLPYSRP
                     KGKKGLLSKNEFLYDEYFDCYICPQDQMLAFSTVTREGYREYKSNPKECVNCPLLNQC
                     TISKNHQRVITRHVWGDLMDEVEHLRLTDLNKSIYKKRKQTIERIFADAKEKHGMRWT
                     KYRGLEKVATHTMLVFAAMNLKKLATWLWKGKEPLFFCSKIRNEVDKKLFQARVTSLE
                     QLLSTVWLSVRTAFFVG"
     gene            1187..1831
                     /locus_tag="PB779_001586"
                     /pseudo
     CDS             1187..1831
                     /locus_tag="PB779_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
     gene            2059..3348
                     /locus_tag="PB779_001587"
     CDS             2059..3348
                     /locus_tag="PB779_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0739113.1"
                     /translation="MLKKNLVIGVVSVLSVISLAACGSGNTKTTKKSEGRVTIEYWHV
                     NADTLGGKTVNELVDKYNQSQDKVKVVAKYNPDMYKGLMQNLQASVASKEIPDVVQVG
                     WAFKDYFAENFKYTNPQSLVEEVDPDNADYFKDHFLDNIMALSEKDGKQVGIPYSISN
                     PVLYLNQDILKAAGLDENGPKTWEEVQTFSKIIKEKTGKYGVYIQEPADNWAQQAILE
                     SNGASVIKDGKATFASKDGIAAYELYQRMVKDQTALHTTWEQGVQSFIDGNVAMVYTT
                     IAQRDNIQKNSTFTAKAVESPSWEGKKVKLPAGGAMLAVTSQTDKKKEATWDFLKYLY
                     SVESLAKWTEGTGYLPPRKDVADAQNGLKAFLAENQMMIPAIDQMDKMVSWSSFPGDA
                     GLEAEQKLLDMRDKILSGNSVNETMKATQKEINELLK"
     gene            3433..4305
                     /locus_tag="PB779_001588"
     CDS             3433..4305
                     /locus_tag="PB779_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0739114.1"
                     /translation="MKRYVGYLYLAPAIILLGVFVFYPLIYTIYLSFFDWNMVAPTKE
                     FVGFANYVKVLTDPVFHKVLKNTLSYTVLFVLLSCVFPYITSFLLGIVIEKGQNLYKP
                     LFFIPAVISLVVAGMVFTWILNPVSGPIAVLLGNFGLRLPMWMNLQGWVIAVIAGITA
                     WKVFGYNFIVIFAAIVGIDQEMIEAAKLDRVPIWRIFFTIVLPMSSSTGLYLLVMTIV
                     QGLQYVFTPIKIITRGGPNNGSANVIYYAYQKAFEMYKVGESSAISVLTLLIFAVFLG
                     VIFKFVEKGVYYEN"
     gene            4295..5110
                     /locus_tag="PB779_001589"
     CDS             4295..5110
                     /locus_tag="PB779_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0739115.1"
                     /translation="MKIKRWLPHLLFMFIIIIIIYPLLFIMANSFKPLKDAYQTITSL
                     IPQPFTLENFCYLFENLPIIKITRNTFFIATIITVVKLGVAFFAAYSFTYCRIKGKKI
                     WYFIIIGTMFIPFTVAMIPNYLLIAKLNLIDTTWGVIIPQFADAMGIFLLTQTMREIP
                     VSLLDVAALDNIKQTTVMSKIVFPLTRHAITSTGIWFFITSWNEYVWPVLILRTVDNY
                     TLPLAMQTYISSEGGTNFTVAMAISLITMFVPLVLYAIFQKYIIGTFVSAGIK"
     gene            5126..6250
                     /locus_tag="PB779_001590"
     CDS             5126..6250
                     /locus_tag="PB779_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739116.1"
                     /translation="MGETLELRNIGKKYGEHTILKEIDLAVAAGERIVLLGPSGSGKS
                     TLLRMIAGLEKITSGELFLGTQLANKLPCGEREIAMVFQNYALYPHMTVKENIIFALR
                     ANKIKTADIQHRLEEALKMLGLTPYQDRLPKDLSGGQRQRVALARAVVKRSNYFLLDE
                     PLSNLDVRLRLDARKELVKIHQRYKQTFVYVTHDQIEAMTLADRIVLLNEGRIQMIDT
                     PKNVYTKPKNTFTANFIGSPGMNIMPVTYDQGTLKVASQFLTLNPAWQKQLLQVSGSL
                     YLGIRPEHVTFSKETSDLHGQVKYRELLGQSYAYTVKVDGIEMIVLNEKPTWQIGDAV
                     NLRIEPERMHFFDYQTQENLGYPDYFIEERGNSHALFASL"
     gene            6228..7031
                     /locus_tag="PB779_001591"
     CDS             6228..7031
                     /locus_tag="PB779_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HDE0739117.1"
                     /translation="MRFLHLSDIHFRENYQTNLFTAELFPTIKNPQLALEKLLQELSL
                     TVYDFILLTGDLVHEGGISDYQVLRKMLDQYFPTTPYYFCRGNHDRRSVFFEGMSVES
                     NETGEYIHCTNQNGLRIISLDSAQDTQHEGKISIGQMIQLQEWLGTPAEKGTILLVHH
                     PLSWEDPSIVTEVPEGFAELIAESDILGIFVGHIHQGSSAEFAGKKQFMAESLSFGVD
                     EYPDYSLFTNRTGFTSGSLIDGKIFTYQHYLTPHQIEIGRMKKPITGNH"
     gene            7482..7754
                     /locus_tag="PB779_001592"
     CDS             7482..7754
                     /locus_tag="PB779_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HDE0739118.1"
                     /translation="MEKMAKLQISMDEKLKNEAESIIDELGMSPKTAVTVFYKQIVEQ
                     GKIPFSIELSEKSKRIHNIQRLAEKLPVQKLDTDEKIEEWFNEDEY"
     gene            7744..8073
                     /locus_tag="PB779_001593"
     CDS             7744..8073
                     /locus_tag="PB779_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDE0739119.1"
                     /translation="MNTNDIATVYVAFTAAEGGKRRPVYILKNGLDTISFLSITSKYH
                     TKSDKIKLKYVEIRDWKQAGLKKESWIDVGTLNELPKNNKKVKWKKIGELSPSDLQRL
                     EERMEEL"
     gene            complement(8252..9466)
                     /locus_tag="PB779_001594"
                     /pseudo
     CDS             complement(8252..9466)
                     /locus_tag="PB779_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            9667..10941
                     /locus_tag="PB779_001595"
     CDS             9667..10941
                     /locus_tag="PB779_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDE0739120.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSP
                     SYCEHCRSVRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQSRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLHFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            complement(11324..12052)
                     /locus_tag="PB779_001596"
     CDS             complement(11324..12052)
                     /locus_tag="PB779_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding response regulator"
                     /protein_id="HDE0739121.1"
                     /translation="MLRIAIVDDDCTIVEGIRHYLLKKVPDIIIDHCYTDGDEAFKNL
                     QNQRFDLLITDITMGKISGLELIESLQQTSNRYFTSIVISAHQNFQYAKKGIDLSIKS
                     YITKPIDFPYLVKLVQEEKMRKSAANQNSLTDDSFNESIQQVIDYVQNNYSEKLTLKD
                     VATQFHYHPAYLGRAFKKETGYSFHDYLLDFRIKRASALLKDTFLSIDEISQKVGIDH
                     VSYFSVLFKKTTGHSPSNYRKKLL"
     gene            complement(12030..13604)
                     /locus_tag="PB779_001597"
     CDS             complement(12030..13604)
                     /locus_tag="PB779_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDE0739122.1"
                     /translation="MKNDLSKVIMRFTYILIFFITLLACFTLFFSYINVIEKEKNQNL
                     QNIQQITHYMETYNRILSGIVTEIYQNYDFQENLNDYYLSSPAEYMEDILSKDRSPTY
                     LVDNLKKLVQDDEVKNISISLDYEKYLSAYAPTKNEKISFIRSLSFISEDMPDATLIL
                     DVSINALKKSLFPTHYNYSLSNGIDSVNLSEDISPSKWKKTQQIAIGNHTLQVYENPN
                     YSSQTLLGLAIMIFLLMSLFILAIHQLLNRSFRNYIQQYQEIITSLNHSSTGDYKSIN
                     IENKVGDLKEIAMHINQFYLDNATYQKTLYENNWLKQEAKYAALQYQIEPHFLFNNLE
                     FIRMTAILNDDEEISDSIYLLSKLYRNNTYQPDIIDLKEELINIDLSLQLHQRRYRHN
                     FDYQLIDHIDQLMLPKLSLQPFVENYIKHGFDSSKKENRLTVYATETTNHYVLKIVEN
                     GKGMDQDKLEHIQQKLNDDIPYSENIGISNSFRRIKHLYPGDTRFVIESQLHVGTTIT
                     IKIQKGGNMHVENCNC"
     gene            13833..14771
                     /locus_tag="PB779_001598"
     CDS             13833..14771
                     /locus_tag="PB779_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0739123.1"
                     /translation="MKLKKGLLGNLKKNRALFIMLLPGALWLFIFCYIPMFGVVIAFK
                     DFRISSRGFFTSLFNSPWVGWENFKYLFASQDAWIITRNTVVYNVVGILLSTFCTVSL
                     AIILSQMANKRLLKKMQTFMIFPNFLSWVVISYFVYAFLSTDKGLINILLSNFGVEPI
                     NWYSEPKYWPFIIVFTSLWKGVGYGSIIYYASIMGIDTSYYEAALVDGASKWQQIRNV
                     VLPHLRSIIVIMLILSVGSIFRADFGLFYQLPRNSGALYDVTNVLDTYVYRGLMNSGD
                     IGMSTAAGLYQSSVGFVLILITNKIVNKLDPSSALF"
     gene            14783..15694
                     /locus_tag="PB779_001599"
     CDS             14783..15694
                     /locus_tag="PB779_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0739124.1"
                     /translation="MISKLKRQMYFSLPVERFFTILLILFTLSCIFPFIFVIVISLTD
                     EKALQLNGYELLPAQWSTDAYQYLIQDGGQLLRSLGVTIMITVIGTLITVFMTGTYAY
                     VLSRASFPYRKFFTFYLFFTMLFAGGMVPSYLVMTKMLGLKNTIWALILPLAFSPYNV
                     IILRTFFKKSIPESIIESAKMDGCSEFRVFFQIVLPLAIPGVATIGLFSSLGYWNDWF
                     NALLYIDTNKLIPLQYLLMKIQNSMEFLANNNDITLAQQQAIQNSLPQESTRMAMVVV
                     ATLPIAIVYPFFQKYFVQGLTIGGVKE"
     gene            15718..17190
                     /locus_tag="PB779_001600"
     CDS             15718..17190
                     /locus_tag="PB779_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HDE0739125.1"
                     /translation="MKKNMQKYLIGGASVLTLGLLGACGSSNGEANNETGTTKVTWYQ
                     VGEEPKDFDEVMTKVNEKLKEEINVELDMRLIPDGDYQQKLGVMINSGEEYDICFVNG
                     TDYVNYGNKGAFISLNDHLDKELKDYAAELNEGFIEGGAINGETYGLPVNNDIATTEY
                     WTFNKDLVDQYQLDVENVEGVETLAPVLEKFAEKNTDTNITPIGMTRTSVCIPYDNII
                     GGGVPLAVAFEGDTQTVVNTYETPEMMTYLKAMHEFYKKGYILKDAATVTTDPFRIDS
                     KNWFLGRNSSGYQPLAQKKLEALAGHGLILKPAGKAFKTTGFARVAMHAVSASSKHPE
                     AALKLLNYVNTNQEVADLMVYGIEGKHYDRNEDGSITLTNSDDYYQGAWALVNTYLVS
                     KTSPITEESKKLEEESKKFQNEAPMSPILGFSFDASDFRTEIASVQNIVSQYEVLLSS
                     GTVDPEQYVPELLEKLEKAGLDKIQASAQEQYDEWRKSNK"
     gene            17241..17852
                     /locus_tag="PB779_001601"
     CDS             17241..17852
                     /locus_tag="PB779_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDE0739126.1"
                     /translation="MNENKWTKGFNWVFQLLLLNFTYFILICLGFGILGFFPATIALI
                     AGVVNRKKYGLQESVKFMSKIYKKNFVRYNLYCWSATLLLAGNITTIWLCWQQSAPLF
                     YLLSTLLSVITLFLVFAMLNWVVIKSLGLWMMGDRLIDYLLFTATMLPTVVMQGLVLG
                     IYFRILMILPVIFLFGGTAVTVILISKLTERALAKLPCQIQSH"
     gene            17882..19795
                     /locus_tag="PB779_001602"
     CDS             17882..19795
                     /locus_tag="PB779_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 20 glycosylhydrolase"
                     /protein_id="HDE0739127.1"
                     /translation="MKLTDKQVANIAFIQQLEIPLTQKDEEQIDLIFTDTKANVRQIK
                     ITKNEQQRICLSYSHEDLLYRGLFICLPRFLAQGGEMPYIEETSIIETSYSLDASRNG
                     VMNKETLKKFISYLALMGYNTLYIYTEDTYEVEDLPYFGYLRGAYTKEEVNEIVEFAS
                     GFGIEVVPSIQTLAHLTQFLKWYAQQELMDDQNTLLIGEEKVYAAIEKMIIACKEMYQ
                     TERIHLGMDEAYQAGLGRYLSLYGYCDRTTLMIQHMDRVLSIVDKYKMKPMIWSDFIY
                     KLLDETGKDRYYNPDFKLKALAAKGLPAGLTYVHWDYGSDEVSSYEKVIDNHLKFCDI
                     DHYVLASGAHIWGRLAPNHGKTEAIVSAAVKASKNKGVRSVMLTTWGDEGQETEHWHS
                     LIGALKLADYVYSEEEWNDFEEIYDRLLGTGSYQLMSELRYFDEVDTITNNNLQMASV
                     SKLLLWQDPLVGIYDFHVAAHNKIATRTIGTYYHELAQKLDMNKNWNPKQPILTTIRQ
                     RYILLAEILAQKAELGIYLQHCCLVEDLAGLMELANRCEALANRVNELASIHEIIWYQ
                     TYKTYGWEVLEQRYAALAHRLKTVARRIKNHLQGQDALEELLEERLPFCQYQVPLEIS
                     GFNYRQSSVSGYN"
     gene            19923..22904
                     /locus_tag="PB779_001603"
     CDS             19923..22904
                     /locus_tag="PB779_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 42"
                     /protein_id="HDE0739128.1"
                     /translation="MLSDYYQNLSVISVNTEPLRNYYIPYASKEEAKQELEREKTSQF
                     IDLNGTWDFQYYPSVQQLPENFFQEAFTESYDRISVPGVWQTEGFDLPQYINVSYPIP
                     FDPPYVPNDTPCGVYRRQFQIEQTDARFYLNLEGADSNCFVWINRNFVGYDQVSHSTS
                     EFDVTKYLQVGVNEIQILVMKWCDGTYFEDQDKWRMSGLFRPVYLLQRPTMHLTSYQL
                     RTLTDPKKGSGTLMVSFQRFTPIEVSLPISYELFHPDGRLIAKGECYSEQQINLDVED
                     CLFWTAETPKLYTLLLTCNGEYFKEKVGFRALTIKNRKLLLNGTPIKLYGVNYHDVNQ
                     QGTPVMTREQLRADLLLMKKLNVNTVRTAHYPKSPDFYELADEIGLYVINEADLECHG
                     VVNLYDTEANYQLIANDPTFEKPIMDRVIRSILPYQNRSSIIMWSMGNESGYGVNFEK
                     AQALARKLDDSRLIHNERSIEPVIDQVNDFSNLDVISQMYPPLEDVHRHCQRSDTEKP
                     FFMCEYSHAMGNGPGDLKTYFDLIQQYDSFLGGCVWEWTDHAINRGTLETPSYLYGGD
                     FGEKYHDGNFCVDGLLTPDRQLTVGALEYRNIHSPIQLIAVDEELQEVTLSNITAFTA
                     GSAFNLSLEWYIDGKKTVYEVMNPFILEPGKSCSLPITVPTTIHGAHTVAVSLSVYKN
                     DELYGQQQLFLKKEKMRLPRTAHHNDAPQISVKGTELIIKGESFIYIYQLAKAAFTSV
                     KINQKELLERPTQFSIWRAPTDNDRNLVNKWKAAGYAEMSLEIRKKDWKFVDDHLLIE
                     TSYRGVIPGLQPIFTMHIQLKINGAGVINQKVSVEKNPIFPDFPRFGMDWPLNDTFSK
                     VSYCGYGPYESYPDKHYAAMFGIYEMEIEEFDQPYIKPQEYGNRWQCDWVSIKNHQGS
                     TMTVYGNSNFSALPYSQAQLTEKSHHYELIKENRTWFNLSYKQNGIGSHSCGPYLEDR
                     FRFMEDTFDWNIVITFKGENR"
     gene            22901..24562
                     /locus_tag="PB779_001604"
     CDS             22901..24562
                     /locus_tag="PB779_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hyaluronate lyase"
                     /protein_id="HDE0739129.1"
                     /translation="MKETKINQVKKKLSRYQEVVYRNHCLKWSKNKLNVRFNGLFYRF
                     EQLEEVWKPVTNFQSCPVQLINDPKETYDLCITHLYNQHLKNDGFYLKVTNDNQLTIE
                     SANLRGFQYAMEALLESFFSVGDQLLLPELILKHEPSVKIRGIIEGFYGIPWTHEMRL
                     SLFSYMKDNQLNTFMYAPKDDELLRKKWRELYDAQELDKFKELLSAAEASNIDFWYLI
                     SPGNDIDITCEEDIQVLLKKLEQLIELGVFQFGLLMDDIDYQLKGAAKRRFREPAFAH
                     AYLVNRVEEYLSTRLSNHELVICPTEYDNRHGSRYLATLSQEIPEQLPFFWTGPSTLA
                     ASISTEELQEMASVYQRPMLIWDNIPVNDYLEDKELLFMSPYENRTPNLSKERYQVTG
                     VVSNPMAQLEASKFTINSMANYLWNCERFDPLETWTSVVEKVVGSKLQPAYLTLTNAF
                     PNHYTSSLLSDEELLLAKDPEWVTKEMAALVQAVKWIQQEQHTSRLRTELEPWLQAIT
                     ESWTFWQEWQLKKDPKEAEEWLAKKKTHRIGRDLVTAHLEQIIKS"
     gene            24602..25534
                     /locus_tag="PB779_001605"
     CDS             24602..25534
                     /locus_tag="PB779_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005229489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDE0739130.1"
                     /translation="MVKRLISANYSDVKKMTSKELKQSIKASEGRVIVCETVANTLPQ
                     SGEITNAEVASAFGADLILLNGFDCYRPAVFGLPNVTIEKVFDLQQTIENPIPKLKEL
                     VGRPVGINLEPIAPKTNMMSEKVEISQGRASSVETIQKAEELGVDFICFTGNPGTGVT
                     NLEITKSVKMAKKYFSGLIIAGKMHSAGSEEPVVNKEAIISYAEAGADILLVPSVGSI
                     PGFLEQDLIEAVRLAKKYDLLTMSAIGTSQESARPETLRQLAIMNKSCGVDLQHIGDA
                     GYGGLAPAENIFETSVAIRGMRHTINCVSRSINR"
BASE COUNT         8328 a         4173 c         5288 g         8054 t
ORIGIN      
        1 agctcgtcaa acaatcgaag agactttttc ctgaaatcaa ttgtgttgtc gctgatgctg
       61 ggtataagac acctaagttt gttcactttt tgactcattt gaaccttcga ccttgtttgc
      121 cttattcaag gcccaaaggg aaaaaggggc tattatcaaa aaatgagttt ctctatgacg
      181 agtattttga ttgttatatt tgtccgcaag atcaaatgct cgctttttca acggttactc
      241 gagaagggta ccgagaatac aaatccaatc caaaagaatg tgtgaactgt cctctgctaa
      301 accaatgtac cataagtaaa aatcatcaac gagtcatcac gagacatgtt tggggagatc
      361 tgatggatga agtggaacat cttcgcctaa cagatctgaa taaatcaatt tacaaaaaac
      421 ggaaacaaac gattgaacga atatttgcgg atgcaaaaga aaagcatggg atgcgttgga
      481 ccaagtatcg aggcttggaa aaagtcgcga cgcatacgat gctagtgttt gctgcaatga
      541 atttaaagaa attagccacc tggctatgga aaggcaagga gcctttattt ttttgttcaa
      601 aaattcgaaa cgaagtagat aaaaagctgt tccaagctcg agttacgagt ttggaacagc
      661 ttttgtctac agtctggctg tctgtgagga cagctttttt tgtgggctag gcatagcaaa
      721 aaggggtagt gacagtccac tgggagggtg cacatcgacc aatcgctaga gaaacgcaag
      781 gtggtatttg tgagaagatg acggaagaaa tcctgtatca aagacttggt tcaacgagca
      841 gaaatctgat agtaagtctc ggtcattcaa tgggaataag ccattgaaca ccttgatggt
      901 atcctgtaag aaagaacctc aaggactttc agcaagaaga aggaatagct gaaaacaaaa
      961 aaaggtgtag taggttaaaa gcggggaatg tagaactact taattggtga aactagctag
     1021 aagggcaaaa tcgacgattc atgagttcgt aggaaggagc atgcaagatt tacaactagt
     1081 ttactgaaaa aacgcaggga atttacaaga aattaacaag aaattaacgc ttcatcggta
     1141 tagtggacgt gtgggagaaa atcacggaat taaaggaggg gtcaaaatga ccatgatcac
     1201 tgcacactct ggtagtgaca atacggagga gaatagctgg gcatttcttc gcttttgttt
     1261 ggatcgccag ctttgttttg aagtagatgt gcgtcagcaa acagatggta cgctaatact
     1321 agcccatgac aggtaagaag ttgtcccaga ttcggtaacc cttgagcagg tgtttcaagc
     1381 agtggccaat gagaaggcaa ccatgaccat taactgtgat ttaaaagaag agggattgga
     1441 aatggccgtt ttttcgctgg cacaaaccta tcaaatctgg ccacaaattg ttcttagtgg
     1501 ctatgtacaa ttatcttggg ctgcgatttg gggaaagcat atattttata atattgaaaa
     1561 tcagttcgaa gggaaaaaac ttggggatat taccgaagca gatttgatcg ataccttaca
     1621 gaaattagcc tatcaaagcg ttcaaatcgt caatattcat gaaggatggt taactaagtt
     1681 ggcccgtgaa gtggggcagc agctaggatt gacattttct gtatggacag tcaatgaact
     1741 agaaacgatt gagtaccttg cgcgctgtgg tgtttataat ataacctcac gttgtgcatg
     1801 ggcctattta tggaagaaag gagcacagaa taaactattt tataatcaaa acagaggagt
     1861 taagagattt ggagatggga tacatgacca tatgggggct ttattcttag cttgatggat
     1921 atgtccagtg accctgtacc ccgaaatgca caaatttcga attatttaca gaaaattaac
     1981 tagaaattta cattggtagt tcataatatt tcttgattag aaaaatggcc ataaagaaat
     2041 taggaggaag ttaatgttat gttaaagaaa aatcttgtta taggggttgt gtctgtttta
     2101 agtgtcatct ctttggcagc ttgtggtagt gggaatacca agacaacaaa aaaatcggag
     2161 ggtcgtgtaa cgatagagta ttggcatgtt aatgcggata ccctaggtgg aaaaacagtg
     2221 aatgaattag tagataaata caatcaatct caagacaaag tgaaggttgt agcaaaatat
     2281 aatcctgata tgtataaagg cttgatgcaa aatttacaag cttctgttgc ctccaaagaa
     2341 ataccggacg tagtacaagt gggatgggct tttaaagatt attttgcaga aaatttcaaa
     2401 tatactaatc ctcaatcttt agtagaagaa gtggatccgg ataatgctga ttattttaaa
     2461 gatcattttt tagacaatat catggcactg tctgaaaaag atggtaaaca agtgggtatt
     2521 ccttactcca ttagtaatcc ggttttatat ttaaatcaag atatattaaa agcagcgggc
     2581 ttggatgaaa atggtccaaa aacttgggaa gaagttcaaa ctttttctaa gataataaaa
     2641 gaaaaaactg gaaagtatgg cgtgtatatt caagaacctg ctgataattg ggcacaacaa
     2701 gcaattttag aaagtaatgg ggcaagtgta ataaaagatg gcaaagctac ctttgcttct
     2761 aaagatggta tcgctgctta tgaattatat caaaggatgg taaaagacca gacggcatta
     2821 cacactacgt gggaacaagg tgtgcaaagc tttattgatg gtaacgtcgc gatggtctat
     2881 accactattg ctcaaaggga caacattcaa aaaaatagta cttttactgc taaagcagtt
     2941 gagtcaccaa gttgggaagg gaaaaaagtt aaactacctg ctggtggcgc aatgttagct
     3001 gttacatcac aaacggataa gaaaaaggaa gcaacttggg atttcttaaa atatctttat
     3061 agtgttgaat ctttagctaa atggacagaa ggtactggtt atttaccacc acgtaaagat
     3121 gttgcagacg cccaaaatgg attaaaagct ttcttagctg aaaatcagat gatgatacca
     3181 gcaattgatc agatggataa gatggtcagt tggagttcat ttcctggaga tgctggatta
     3241 gaagctgaac aaaaattgtt ggatatgcgg gataaaattt tatcaggtaa ttccgtcaat
     3301 gaaacgatga aagctactca aaaggaaatt aatgagttac tcaaataagc aaagcaagca
     3361 gacgacagcg cctgtaagaa aggaaaaaca aggtcgtctg cttttgacat aaggatgagg
     3421 aggctgtcgg aaatgaagcg ctatgtaggt tatttgtatc tggcgccagc aattattttg
     3481 ttgggcgtgt ttgtttttta tccattgatt tatacgatct atttgagttt ttttgactgg
     3541 aatatggtgg cccccactaa agaatttgtt ggctttgcca actatgtaaa ggtgctgact
     3601 gatccagtct ttcataaagt gttgaagaat actttgtcct ataccgttct atttgtcttg
     3661 ctgagctgtg tgttcccata tattacatcc tttttattag gaatagttat agaaaaaggg
     3721 cagaatttgt ataaaccatt attttttatt ccagctgtga tttctttggt agtggcgggg
     3781 atggttttta catggatatt aaatccggta tcgggaccaa ttgctgtctt gttgggaaat
     3841 tttggtttaa gactgcctat gtggatgaat ttacaaggtt gggtaattgc tgtgattgca
     3901 ggtattactg cttggaaagt ttttggttat aatttcattg tcatttttgc agcaattgtg
     3961 ggaattgatc aagagatgat cgaagcagct aagttggatc gtgtacccat ctggcgcatt
     4021 ttttttacaa ttgtgttgcc tatgagtagt tcgacaggac tatatttatt ggtgatgacc
     4081 attgttcaag gtctgcagta tgtgtttact ccgattaaga tcatcactcg tggtggaccg
     4141 aataatggta gtgcaaacgt gatctattat gcttatcaaa aggcttttga aatgtataaa
     4201 gtcggagaat cttcagcaat ttcagtttta actttattaa tatttgctgt tttcttaggg
     4261 gtaatattta aatttgtgga aaagggggtt tactatgaaa attaaacgct ggttgccaca
     4321 tctcttattt atgttcatca taatcattat tatctatcca ttattgttta ttatggccaa
     4381 ttcttttaag ccattgaaag atgcctatca gacgattact agtttgatac cacagccgtt
     4441 taccttggaa aatttttgct atttgttcga aaatcttcca attatcaaaa ttacgagaaa
     4501 tacttttttt attgctacaa ttataacggt tgttaagtta ggcgtagctt tttttgcggc
     4561 atatagtttt acttattgcc gaatcaaagg gaagaaaatc tggtacttta tcatcattgg
     4621 tacgatgttc attcctttta ctgttgcgat gattcctaat tatttgttga ttgcaaaact
     4681 taatttaatt gatactactt ggggtgtgat aataccacaa tttgctgatg cgatgggcat
     4741 ttttttattg acgcaaacaa tgcgggaaat tccagtgagc cttctagatg tggcggcatt
     4801 ggataacatc aaacaaacaa ccgtcatgag taaaattgtt tttcctctta ctagacatgc
     4861 gattacttct accggtattt ggttttttat tacctcttgg aatgagtatg tttggccggt
     4921 attaatttta cggacagtag ataattatac tttgccgttg gcgatgcaga cctatattag
     4981 ttctgaaggt gggacaaatt ttaccgtagc aatggcgatt agtttaatta caatgtttgt
     5041 accgttagtc ttgtatgcaa tttttcaaaa atatattatc gggacttttg tttctgcagg
     5101 tattaaataa attggaggac aaatcatggg agaaacgctt gaattaagaa atatcggaaa
     5161 aaaatatgga gaacatacca ttttaaaaga aattgattta gctgtggccg ctggagaacg
     5221 aattgtgtta ctgggaccat ctggttcagg aaaatctact ttgctgagaa tgattgctgg
     5281 tttggaaaaa attacgagtg gagagctttt tttaggtaca caactagcaa ataagctacc
     5341 ttgtggagaa cgagagatcg caatggtttt tcaaaattat gctttatatc ctcacatgac
     5401 tgtaaaggag aatattattt ttgcattaag ggcgaataaa attaagacag ctgacattca
     5461 gcaccgtttg gaagaagctt tgaagatgtt aggtttaacg ccataccaag atcgacttcc
     5521 taaagatttg tcaggagggc aacggcagcg tgtagcattg gctcgtgcgg tggttaaacg
     5581 gagtaattat tttttattag atgaaccgtt atcaaatttg gatgtgcgtt tacgattgga
     5641 tgcacgaaaa gaattggtaa aaattcatca acgttataaa caaacttttg tctacgtcac
     5701 tcatgatcaa attgaagcga tgacgttagc tgaccggatt gttttattga atgaaggtag
     5761 aattcagatg attgatacgc cgaaaaatgt ttatacgaaa cctaaaaata cttttactgc
     5821 aaattttatt ggttcgccag gcatgaatat tatgccagtt acttatgatc aaggaacatt
     5881 aaaggtagcc agtcaatttt taacattgaa tccagcttgg caaaaacaac ttcttcaggt
     5941 tagtggctca ttgtatttag gcataagacc agaacacgta accttttcaa aagaaacaag
     6001 cgatttacac ggtcaagtga agtatcgtga gctattaggt caaagttatg cgtacaccgt
     6061 taaagtcgat ggtatagaaa tgattgtcct taatgaaaaa cctacttggc agattggtga
     6121 tgcagtcaat ctccgcatag aacctgaaag aatgcatttt tttgattatc agacgcaaga
     6181 aaatttagga tatcctgatt attttattga agaaagaggg aatagccatg cgctttttgc
     6241 atctctctga tatccatttt agagaaaact atcaaactaa cttgtttact gctgaactat
     6301 ttccaacaat taaaaatcca cagttggcat tggaaaaatt gttacaagaa ctctcgttaa
     6361 cagtgtacga ttttattcta ttaacaggtg atttagtaca tgaagggggg atttctgatt
     6421 atcaagtctt acggaaaatg ttggatcaat atttcccaac cacaccttac tatttttgtc
     6481 gtgggaatca tgatcgtcgc agtgttttct ttgaaggaat gagtgttgaa agcaatgaaa
     6541 cgggagagta tatccattgt acgaatcaaa atgggttacg aattatttcc ttggattctg
     6601 ctcaagatac ccagcacgaa ggaaaaatat cgataggaca gatgattcaa ttacaagagt
     6661 ggttgggtac acctgctgaa aagggaacga ttttattggt tcatcatcca ttgtcgtggg
     6721 aagatccatc tattgtaact gaagttccgg aaggttttgc tgaattgatt gccgaaagtg
     6781 atattttagg tatttttgta ggacatatcc atcaaggtag cagtgctgaa tttgctggta
     6841 aaaaacagtt tatggctgaa tctttatcat ttggtgtaga tgaataccca gactattctc
     6901 tttttaccaa tagaacagga ttcactagtg gcagtttaat tgacggaaaa atttttactt
     6961 atcagcatta tttaactcca catcaaatag aaatagggcg catgaaaaaa ccaattactg
     7021 gtaatcatta aaaattattg attaaaaata aagacttcat tcacttttta gccgtggtgc
     7081 tcaatgtctg gttccacttg aagaacttgg aaaatcgcta tcaataaacc actatccctc
     7141 caattacaaa aagggtggag aaagttttcc aagaaccata tcggtcttcg tggttgtgcc
     7201 attcgttttt taccagagca taccacatct ttgtggagtt ttcagacacg tcctagttaa
     7261 tttggttctt ttaggagtct tttcctgttc tgtgtgtcgt tgagtgttcg cttcaattat
     7321 cgctgtggcg gattttgaaa cttttctatc tatcaaggcc atttagcact atatcctttc
     7381 cttatattta gataaataca ctgcatttca aggagttcaa aagtagttgt attaattcca
     7441 tttgaactct ttccgtgata taatgtgttt gtcagaaaga ggtggagaaa atggctaagt
     7501 tacaaatttc tatggacgaa aaattgaaaa atgaagcaga aagcattatt gatgaactag
     7561 gcatgagccc caaaacagcc gtcaccgttt tttataagca aattgttgag caaggaaaaa
     7621 tcccattttc tattgaattg tcggaaaaaa gtaaacgaat ccataatatt caaagattag
     7681 cggaaaaatt gcctgtccaa aaactagaca ctgacgaaaa aattgaagaa tggttcaatg
     7741 aagatgaata ctaatgatat agcaaccgtc tacgttgctt tcacagctgc agagggcggt
     7801 aaacgccggc ctgtctatat tctaaaaaat ggactggaca caatttcgtt tctgtcaatt
     7861 acttcaaaat atcatactaa atccgataaa ataaagctga aatacgttga aataagggat
     7921 tggaaacagg caggactaaa aaaagaatct tggattgacg taggaactct aaacgaatta
     7981 cccaaaaaca acaaaaaggt caaatggaaa aaaattgggg aattaagtcc aagcgattta
     8041 cagcgactgg aagaacgcat ggaagaatta taataatact aaaaagaagg gctctttgtc
     8101 aataaggact gatgggttgt acaaaatcaa atctgggtca gaatgaacct cattctggct
     8161 cagatttttg gctctttgtc aataaggact gatgagttgt gcaaaatcaa atccgggtca
     8221 gaatgaacca cattctggtt cagatttttt gttatcttac attgattaat tgattgatca
     8281 aaaagattct aattctcatg ttctcgaatg atttaaatcc gtaggatact cgtttcattg
     8341 tctttatgtg ggtattcttc gcttcaattt ttccattgga ataaggatag atcattgcgc
     8401 tggtgatacc ttcttcatag gtcagaaggt tttgaagctt ctcccgaaag ccgtcatcta
     8461 acgtttcggg aagttctgcc aataaggaga aaaataagtc agggtctttg tctcgaaagg
     8521 cttcgactaa ttcatgaaaa aagggatacg cctcctttag aggcgcagaa aactcaagca
     8581 atcgatcaat catcattgct tcagtgagaa atgggtattt tggtgctcgg aaacttttcc
     8641 atgttttgta ctcataatgg ttgatgcttg cacgattttt tagcagaaag cgccagttct
     8701 ttttcagttt ttctgcctga cttttctgtc ctgctttacg aagctcattc atttcacgga
     8761 tacgcaactc attgagtgcc tgattcatgt gtttgacaat atgaaaccga tcaatcacta
     8821 ctttcgcatt tggcagaaca cgtttggtaa gctggaagta agcggcgttc atgtctgtga
     8881 ctaagaattc tacttcttct ggattggtgc agcctaagaa atagcttgtt aatcgaggta
     8941 atttacgcgt aggcaagaca gcaattaagt ttcctgtttc accatctgcg caaataaagc
     9001 tcattttatc ttctatggaa gcgtgcgaac gaaattcatc aaccatcaat actctgggga
     9061 gaatcttctt agaaggcttt ggtaaatagc ttttaaactc tttcaatgta cgagtaacgg
     9121 tagtcaaaga tacctgacaa cttttcgcaa taaaagacaa agatactttt tcagtcagta
     9181 aagaagcaat tttatatcga acatgatctg cgattgaatg gctgagtcgg acaaaataac
     9241 tttgagccgt ccaatgggta cgacagtttt tacaggtata gcgttgcttt tttaggcgcg
     9301 taaccaaagg catatgattg tattgttcaa aacggacaat cgtttccttc ttcccatttt
     9361 tcactataat tgctttcccg tttccatcta ccacagtaga accacaactt ctacaagcac
     9421 gaggagtagg cgagagaaca gcatcgacga ccaacgtctt tttcttggct ctttgtcaaa
     9481 taggactgat agagtgatat aagaacatct aaggtagaat tgattttgct tctataatat
     9541 tttgtgttgg tggaaaatcg aaggcgattt tctactaaca ctttttcttc gtttcaactc
     9601 aaaaagagac tcacttttgg taaaatttag tcgaccaaaa cgtcatccta ccaaaggagt
     9661 ctctcaatgg ataatcatac tagaaaatta ctcggattaa cagataaaca tttatttttt
     9721 gatgaagaat ggctgattga aaaagaatat aaaggcgttc aagcgcagtt tattaaagga
     9781 aaattggatg actctccttc ctattgtgaa cactgtcgat cggttcgtat tatccgcaac
     9841 ggttcctata cgacacgcac tcagatattg aaagtcaaag aaaagttaac tattttagaa
     9901 ttaaaacgta cccgttttct ctgccatgat tgtggaagga ccttttctgc gaaaacggac
     9961 ttagttgatg aacatcatca actaacaaag gaactgaagc aggcaattct catggaactg
    10021 tacgaaaatc aatcacgtaa actaatcgct aagaagtact tcgtctcgga tgggacggtg
    10081 acacggatct tgcgtgaagc aacgaagcat taccagtcac gtatgaactt ccttccgacg
    10141 gtgttgtgta tggatgagtt caaatcaatg aagtctgttt ctggttccat gagttttatt
    10201 tgtgttgatg ggacaaccca tcagctattt acgatccttg aagatcgcag actttacaaa
    10261 ctaactcaat acttcctgca ctttcctaga aaagcccgtt taaaggtcaa gtacctagtg
    10321 atggacatga atgccagcta ttgtcagttg cttaaaacag tctttccaaa tgcggagatc
    10381 gtaactgacc gctttcatat tgtccaacac atcaatcgca gcttcaatca attacgtgtc
    10441 cagatcatga atcgttttcg aacctcacac tctgaaaatc agaagaagta ccgtcggctc
    10501 aagcgatatt ggaaactctt actcaaagat tccacgacat gggagccact caaacggcat
    10561 tatcatcgac tgtttaaacg accaattagt caaacagaaa tcgttgatga gctgttaagc
    10621 tacaacgaag aattgcgaac tgcgtatcat ttttgtcaat tattacgcta ttatttcgtt
    10681 aaacgaggta cggaaggctt tcaagaaacc cttaaaacaa tttcatctac gttacctcag
    10741 tcgtttaaaa agaaattcac gatcttccat tgctaccaat cgggtatttc aaatgccttt
    10801 aaggtgtccc actcaaacgg cgtcactgag gggctgaata acaagatcaa gctgattaaa
    10861 cgaattgcgt ttggttatcg caacttttat aactttcggg cacggatcta tttacaacaa
    10921 ggtctgatct ttgaaaacta aaaaaatatg cggcgcacag aacgcgccgc atatcggact
    10981 aagttttatt caaatttgtc ttcaccaaca cgatttgacg aagagcctat ttaaataact
    11041 acatccattt attctatctt ctaaaatagc ctttttcatt tcagttaaat agttcagcgc
    11101 catttttgca ctcgacttgc atagtagttt tttccatatt cctcaacctc agcgggggtt
    11161 gaagacataa ggaaaatcct atgcgttatg ctcaactgga tctgattaaa tattctaatg
    11221 tatttttctc taccatcatt aaatggttaa tagccaaaaa tcaccacttt tcaatggctc
    11281 cttgttgtat aagtataact agaagatgaa cacgtctgag aaattataga agctttttac
    11341 ggtaattact ggggctgtgt ccagtagttt ttttgaagag aacagaaaaa tagctcacgt
    11401 gatctattcc tactttttga ctaatttcat caatagataa gaatgtgtct ttcagtagag
    11461 cacttgctct tttgattcga aagtctagca agtaatcatg aaaggaataa cctgtttctt
    11521 ttttgaaggc ccgtcctaaa taagcgggat ggtaatggaa ttgtgtagct acatctttga
    11581 gtgtaagctt ttcactataa ttgttttgaa cgtaatcaat cacttgttga attgactcat
    11641 taaaagaatc atcagttaga gagttttgat tagctgctga tttacgcatt ttttcttctt
    11701 gtactaactt aactaaataa ggaaaatcaa tgggtttcgt tatgtaactt ttaatagata
    11761 aatcaatccc cttttttgca tactgaaaat tttggtgggc actaatgaca atactagtaa
    11821 agtagcgatt ggatgtttgt tgcaaagatt cgattaattc gagtccagaa attttcccca
    11881 tcgtaatatc tgtgataagt aaatcaaagc gctggttttg caggttttta aatgcttcgt
    11941 ctccgtctgt gtagcagtga tcgataatga tgtcggggac tttcttcaaa agataatgcc
    12001 ttatgccttc tacaattgta caatcatcgt caacaattgc aattctcaac atgcatattc
    12061 cccccttttt gtattttgat agtaatcgtt gttccgacgt gtagttggct ttctataaca
    12121 aaacgtgtat ctccaggata gagatgcttt atacgtcgaa aagaatttga gatgccgata
    12181 ttctcactat aaggaatatc atcattaagt ttttgttgaa tatgctccag cttgtcttgg
    12241 tccattcctt tcccattttc aacgattttt aacacataat ggttggttgt ttcagttgca
    12301 tagacagtca aacgattttc cttttttgat gaatcgaagc cgtgtttaat ataattttca
    12361 acaaatggct gtaaagaaag ttttggtaac attaattgat caatatgatc aatcagctga
    12421 tagtcaaagt tatgtcgata acgacgttga tgtagttgca aggagaggtc gatattaatt
    12481 aattcctctt tcaaatcaat tatgtcgggc tgatatgtat tattgcgata caacttgctc
    12541 aataaatata tactgtcgct gatttcttcg tcatcattca atatggcagt cattcgaata
    12601 aattccaaat tattaaatag aaaatgaggc tcgatttgat attgaagtgc tgcatacttt
    12661 gcttcttgct tcaaccaatt attttcataa agtgtttttt gatatgtagc attatctaaa
    12721 taaaactgat tgatatgcat agcgatttct ttcaaatcac cgactttgtt ttcgatattg
    12781 attgacttgt agtctcctgt agatgaatga tttaaggaag taatgatttc ctgatactgc
    12841 tggatatagt tacgaaaact tctatttaat aattgatgaa tagcaagaat aaacaaactc
    12901 attaataaga aaatcatgat tgccagacct aataaggttt gtgacgaata atttggattt
    12961 tcatatactt gtaatgtgtg gttaccgata gctatctgtt gcgttttttt ccatttagaa
    13021 ggcgagatgt cttcagataa attgacggaa tcaataccat tagacaaaga ataattgtaa
    13081 tgtgttggaa agagactctt ttttagcgcg ttgatcgaaa cgtctagaat caatgtagca
    13141 tcgggcatgt cctcactaat gaaacttaat gaacgaataa aagaaatttt ttcgtttttt
    13201 gtaggtgcgt aggcacttaa gtatttttcg taatctaatg agatagatat atttttaact
    13261 tcatcatctt gcacaagttt ttttaagtta tctactaaat aggtagggga gcgatccttt
    13321 gacaaaatat cttccatgta ttcagcaggt gatgagaggt agtagtcatt aaggttttct
    13381 tggaaatcat aattttgata gatctctgtc acgataccgg agagaatacg attatatgtt
    13441 tccatatagt gggtgatttg ctgaatgttt tgcaggtttt gatttttttc tttttcaatc
    13501 acattgatat aggaaaagaa caatgtgaaa caggcaagta aagtaataaa aaaaatcaat
    13561 atgtatgtaa aacgcataat aacttttgat aaatcgtttt tcattcaaag tcctcatttt
    13621 gataatctct aattttatga atcattatag cacatattac aagtgatgta aacgctttgc
    13681 aaacagggct acttatgatt gtgaatacag tttccgttta aaaactattc tattgtagag
    13741 gtttaataaa ctaaaaataa tgtataaaaa attaatgtaa gcgattaacc aagtgggtat
    13801 aatcaaggaa acgctgagag aggagagaca aaatgaagct aaagaaaggg ttattaggaa
    13861 atctaaaaaa aaaccgagca ttgtttatta tgcttttacc aggtgcgtta tggttattta
    13921 tattttgcta tataccaatg tttggagttg taatcgcttt taaagatttc agaatttcat
    13981 caaggggatt ctttacaagt ttgttcaaca gtccttgggt tggctgggaa aatttcaaat
    14041 atctctttgc ttcgcaagat gcttggatca ttactcgcaa tacggttgtt tataacgttg
    14101 taggtatttt gctaagtact ttttgtacag tgtcattagc aatcattctg agccaaatgg
    14161 cgaacaaacg gttattgaaa aagatgcaga catttatgat ttttcctaat tttttatcat
    14221 gggtagtcat cagttacttt gtttacgcat ttttgagtac ggataaagga ttaattaata
    14281 ttttactaag caattttggt gtggaaccca taaattggta tagtgaaccg aagtactggc
    14341 cttttattat tgtttttacg agtttatgga aaggcgtagg ctatggatcc atcatttatt
    14401 acgcgtcaat tatggggatc gatactagtt attatgaagc tgctttagtt gatggtgcca
    14461 gtaaatggca acagataagg aatgtagtct tgccacattt aagatcgatt attgtcatta
    14521 tgttgatttt gtctgttggt agtatttttc gagctgattt tggattgttt tatcaattgc
    14581 caagaaattc gggggctctt tatgatgtga cgaatgtatt agatacttat gtctaccgtg
    14641 gattaatgaa tagcggagat atcggaatgt ctacggcagc gggattatat cagtcatcag
    14701 ttggctttgt cttgattttg attactaata agatagtcaa caagttagat cctagttcag
    14761 cactatttta ggaggaatca aaatgatatc aaaattaaaa cggcagatgt acttttcgct
    14821 gccagtcgaa cggtttttca caatattact aatcttattt actcttagct gtatttttcc
    14881 ctttattttc gtaatcgtca tttcattaac agatgaaaaa gcattacaac tcaacggtta
    14941 cgaattattg ccggctcaat ggagcactga tgcatatcaa tacttaatac aagatggcgg
    15001 acagttactt cggtcattag gcgttacaat tatgattaca gtgattggaa cgttgattac
    15061 tgtttttatg acgggaacct atgcttatgt tttatcaaga gcctctttcc cttaccggaa
    15121 gttctttact ttttatcttt tttttaccat gttatttgcg ggagggatgg ttccttctta
    15181 cttagtgatg acgaagatgc ttggcttaaa aaatacaatt tgggctttga ttctacctct
    15241 tgcttttagc ccatacaatg tcattatttt aaggacattc tttaagaagt cgattccaga
    15301 atcgattatc gaatccgcta aaatggatgg ctgtagtgag tttcgagttt ttttccaaat
    15361 cgttttgcct ttagcgatcc caggggttgc aacaataggt ttattttcaa gcttaggtta
    15421 ttggaatgac tggttcaacg cattgctgta tattgacacc aacaaattga ttccattgca
    15481 atatttgtta atgaagattc aaaattcaat ggaattctta gcaaataata atgacattac
    15541 attagcgcag caacaagcaa ttcaaaatag ccttcctcaa gaatcaacac gaatggcaat
    15601 ggtcgtagta gctactttac cgattgcaat tgtttatccg ttcttccaaa aatactttgt
    15661 tcaaggattg acgatcggtg gagtgaaaga ataaaaaaga ataggagatg ttaaaagatg
    15721 aaaaagaaca tgcagaaata tttgattggt ggtgcttctg tactaaccct tggcctatta
    15781 ggtgcttgtg gtagcagtaa tggcgaagca aataatgaaa caggaaccac aaaagttact
    15841 tggtatcagg ttggagaaga acccaaagat tttgatgagg tcatgacaaa agtcaacgaa
    15901 aaattaaagg aagaaatcaa tgtagagttg gatatgcggc tgattccgga cggggattat
    15961 cagcaaaagc ttggtgtgat gatcaattca ggagaagaat atgatatttg tttcgtcaat
    16021 ggcacagatt atgtgaatta tgggaacaaa ggtgctttca ttagtctcaa cgatcatttg
    16081 gataaagagt tgaaagatta tgcagctgaa ttgaatgaag gatttattga aggtggggca
    16141 attaatggcg aaacttatgg attgccagtc aataacgata ttgccacaac ggaatattgg
    16201 acctttaata aagatttggt agatcaatac caattggatg tagagaatgt tgaaggtgta
    16261 gaaacattgg ctccagtatt agaaaagttt gcagaaaaaa atactgatac gaatattacg
    16321 ccaatcggta tgacccgtac cagtgtctgt attccttatg acaatattat cggtggtggt
    16381 gtaccgctag cggttgcatt tgaaggcgat acacaaacag ttgttaatac ttatgagact
    16441 ccagaaatga tgacttattt gaaggctatg catgagtttt ataaaaaagg atatattttg
    16501 aaagatgcag ccactgttac gacagatcca tttcgaattg atagtaaaaa ctggttttta
    16561 ggtcgtaact caagtggtta tcaaccatta gcacaaaaaa aattagaagc tctagcggga
    16621 catggattaa ttttaaaacc agctggaaaa gcttttaaaa cgactggatt tgcaagagtg
    16681 gcaatgcatg cggtatctgc ttcaagtaaa catccggaag cagccttgaa attgttgaat
    16741 tatgtgaata ccaatcaaga agtagcggat ttaatggttt atggaattga aggaaaacac
    16801 tatgatcgca atgaagatgg ttcgattact ttaacaaact ctgatgatta ttatcaaggc
    16861 gcttgggcat tggtaaatac ttatctagtt tcaaaaactt caccgattac agaagaaagt
    16921 aaaaaactag aagaagaaag taaaaagttt caaaatgaag caccgatgtc tcctatttta
    16981 ggtttctctt ttgacgcttc tgattttcga acagaaattg caagtgtaca aaatatcgtg
    17041 tcacaatatg aagtactttt aagctcggga acagttgacc ctgaacaata tgtaccagag
    17101 ttgttagaaa aactagaaaa agctggattg gataaaattc aggcatctgc tcaagaacaa
    17161 tacgatgaat ggcgaaaatc taacaaataa ttttttacta aatgaaaaga atagactaag
    17221 cagttagtgg ggggattcaa atgaacgaaa acaaatggac caaaggattt aattgggttt
    17281 ttcaattgtt gttactaaac tttacttatt ttatactaat ttgtttagga tttggaattt
    17341 taggtttttt ccctgctacg atagctttga ttgctggcgt tgtgaatcga aaaaaatatg
    17401 gcttgcaaga gtctgtgaag ttcatgagta aaatctataa gaaaaatttt gttagatata
    17461 atctatattg ctggtcagca actttgttgt tggccggcaa tattactacg atctggcttt
    17521 gttggcagca aagcgcacca ttgttttatt tattaagtac attattatcg gtaattacac
    17581 tgttcctagt ctttgcaatg ttgaattggg tcgtgatcaa aagtcttggg ttgtggatga
    17641 tgggagaccg actgattgac tatttgcttt tcacagcaac gatgttgcca acggtagtca
    17701 tgcaaggctt ggtgcttgga atttatttcc gaatattgat gattttgcct gtgatttttc
    17761 tgtttggcgg aacagctgta acggtaatat tgattagtaa attaactgaa agagcgttag
    17821 caaagttgcc ttgtcagata caatcgcact aattttttca caaaaaggag tatttctttc
    17881 tatgaagtta actgataaac aagtagctaa tatagccttt atccagcaac ttgagattcc
    17941 attgacacaa aaagatgaag aacaaataga cttgattttt actgacacaa aggctaatgt
    18001 gcgacaaatc aagattacta aaaatgagca gcaacgaatt tgcttgtctt attcacatga
    18061 agacttgctg tatcgaggat tgtttatctg ccttccacgt tttttagctc aaggaggaga
    18121 gatgccatac attgaagaaa cctcgatcat tgagaccagt tattcattag atgcttctcg
    18181 taatggcgtg atgaataaag agactctaaa aaaattcatt tcttacttag cgttgatggg
    18241 gtacaacaca ttgtatattt acacagaaga tacctatgaa gtagaagacc ttccatattt
    18301 tggttacctt cgcggagcgt atacaaaaga agaagtgaat gaaattgttg aatttgcttc
    18361 tggttttggc atagaagtag ttccatcgat ccagaccctt gctcacttga cccaattttt
    18421 gaagtggtat gctcaacaag aactgatgga tgatcaaaat actctactga tcggtgaaga
    18481 aaaggtttat gcggcaatcg aaaagatgat tattgcctgc aaagaaatgt atcagacaga
    18541 gcgtattcat ttgggaatgg atgaagccta tcaagcaggt ctgggacgat atttaagcct
    18601 gtatgggtat tgtgatcgga caactttaat gattcaacat atggaccgtg tgttatcaat
    18661 tgttgataaa tataagatga aaccaatgat ttggagtgat ttcatttata agctattaga
    18721 tgaaaccggt aaagataggt attacaatcc tgattttaaa ctcaaagcat tagcagctaa
    18781 aggattacca gcaggattaa cctatgttca ttgggactat ggttcagatg aagtttcctc
    18841 ctatgagaaa gtaattgata accatttgaa attttgtgac attgatcatt acgttttagc
    18901 tagtggtgcc catatctggg ggagactagc cccgaatcat gggaaaacag aagcaattgt
    18961 ttctgcagct gtaaaagctt ctaaaaataa aggtgtacgt tctgtgatgt taactacttg
    19021 gggagatgaa gggcaggaaa cagagcattg gcattcctta attggggcat taaaattagc
    19081 agattatgtc tattctgaag aagagtggaa tgattttgag gaaatctacg atcgtttatt
    19141 aggaacaggt agttatcaat taatgtccga attacgatat ttcgatgaag tggataccat
    19201 tacaaataac aacttacaaa tggcttccgt gagtaaactg ctactttggc aagatccgtt
    19261 agttggtata tatgactttc atgtagccgc tcataacaaa attgccacta gaacaattgg
    19321 tacttattat catgagttag ctcagaaatt agatatgaat aaaaattgga atccaaaaca
    19381 accaatttta acaactattc gtcaacgata tatactttta gctgaaattt tagcacaaaa
    19441 ggcagaacta ggcatctatt tacaacactg ctgtctggta gaagaccttg caggattaat
    19501 ggaattagcg aatcggtgtg aagcactagc caatcgagta aatgaattgg catctattca
    19561 tgaaataatt tggtatcaaa catacaaaac ctatggttgg gaagtattag aacaacgata
    19621 tgctgcatta gctcatcgtc tgaaaaccgt tgcgcgtcgt attaaaaatc atcttcaggg
    19681 gcaagatgcc ctagaggagc ttttggaaga acgattaccg ttttgtcaat atcaagtgcc
    19741 gcttgaaatt tctggcttta attatcggca aagctcggtg tcaggctaca attaacgaag
    19801 gaatcttccc gttgaacgga ccacttgctc atctaatggg aaagtggttc gttttctatt
    19861 cataagtagc ttaccactaa ctcttttatt aagaagagaa aaaaagtagg aagtgagaaa
    19921 atatgttatc ggactattat caaaatctgt cagttataag tgtcaataca gaaccattac
    19981 gtaattatta tattccttat gcaagtaaag aagaagcaaa acaagagtta gaaagggaaa
    20041 aaacgagcca gtttatcgat ctcaatggta catgggattt tcagtattat ccttctgtcc
    20101 aacagttacc ggaaaatttt tttcaagagg cctttactga aagctatgat agaatttctg
    20161 ttcctggagt ttggcaaaca gagggatttg acttacctca gtatatcaat gtatcttatc
    20221 caattccttt tgatccgcct tatgtaccta atgatacccc ttgtggtgta tatcggcgtc
    20281 agtttcaaat tgagcaaaca gatgcacgct tttacttaaa tctagaagga gcagatagta
    20341 attgttttgt ttggataaat agaaactttg taggctatga ccaagtgagt catagtacat
    20401 ctgaatttga tgtgaccaag tatttacagg ttggggttaa tgaaattcaa attctagtga
    20461 tgaagtggtg tgatggtacc tactttgaag atcaggataa gtggcgaatg agcggtctat
    20521 ttcgtccagt gtatcttctt caacgaccaa ctatgcatct gacaagttat caactacgga
    20581 cgttgactga tcctaaaaaa ggaagcggaa cattaatggt ttcttttcaa cgatttactc
    20641 ctattgaagt atcgttacct atttcttacg aattattcca tcctgatgga cgtctcatag
    20701 cgaaagggga gtgttactcg gaacaacaaa taaatttgga tgttgaagat tgcctttttt
    20761 ggacagcaga aacgcctaaa ttatatacat tacttttaac atgtaatggt gaatatttta
    20821 aagaaaaagt tggctttcga gcactgacga tcaagaatcg taagttattg ctgaacggaa
    20881 cacctattaa attatatgga gtcaactatc atgacgtgaa tcagcaaggc acgccagtga
    20941 tgacccgaga gcagttacgt gcagatttgt tattaatgaa aaaattaaat gtgaatactg
    21001 tacgaacggc acattaccct aaatcaccag atttttatga attggcggat gagattggtc
    21061 tgtatgtaat caatgaagca gatttggagt gtcatggtgt ggttaatcta tatgatactg
    21121 aagcgaatta tcaactaatt gctaatgatc cgacattcga aaagccgatt atggaccgag
    21181 tgatccgttc tattcttcct tatcaaaatc gaagctctat cattatgtgg tctatgggga
    21241 atgaatctgg ttatggagta aattttgaaa aagctcaagc tttagcacgg aaattggatg
    21301 attcacggtt gattcataat gaacgctcga ttgaaccagt tattgaccaa gtgaatgatt
    21361 ttagtaactt ggatgttatt agtcaaatgt atcccccact ggaagatgtt catcgtcatt
    21421 gtcaaagaag tgatactgaa aaaccttttt ttatgtgtga atatagccac gctatgggca
    21481 acggtcctgg agatcttaaa acgtacttcg atttgattca acagtatgat tcctttcttg
    21541 gcggttgtgt ctgggagtgg actgatcatg caatcaatag aggaacttta gaaacgccat
    21601 cttatttata cggtggtgat tttggtgaaa aatatcacga cggcaatttt tgcgtagatg
    21661 gtttattgac cccagatcgg caattaacag taggtgcatt ggagtaccgt aatattcatt
    21721 cgcctattca actgattgct gtagatgagg agctgcaaga agtaaccttg agcaatataa
    21781 ctgcttttac agccggttca gcatttaacc tttctcttga atggtatata gatggaaaaa
    21841 aaacagttta tgaagtaatg aatcctttca tacttgagcc tggcaaaagt tgttcattgc
    21901 ccatcacagt acctacaacg attcatggtg ctcatacggt tgctgtttcg ctatctgttt
    21961 ataaaaatga tgagctttat ggacagcaac agctctttct taaaaaagaa aaaatgagat
    22021 tgccaagaac tgctcatcat aatgatgcac cacaaatttc agtaaaaggc acagagctga
    22081 taatcaaagg agaatccttt atttatatat atcaattagc aaaagctgcg ttcacttctg
    22141 taaagatcaa tcaaaaggaa cttttggaac gtcctactca attttcaatt tggcgtgcac
    22201 caacggataa tgatcgtaac ttagtaaaca aatggaaagc agctggatat gctgaaatgt
    22261 ctttagaaat cagaaaaaaa gactggaaat tcgtagatga tcatctcctg atcgaaacgt
    22321 cttatcgagg agttattcca ggattacagc caatttttac aatgcacata cagttgaaaa
    22381 taaatggtgc aggcgtaatc aaccaaaaag tatcagtgga gaaaaatccg atttttccag
    22441 atttccctcg ctttgggatg gactggccgt tgaatgatac tttttcgaag gtttcttatt
    22501 gtggctatgg gccgtatgaa agttatcctg ataagcacta tgctgcgatg tttggtattt
    22561 atgagatgga gattgaggaa tttgatcagc catatatcaa accacaagaa tatggtaacc
    22621 gctggcaatg tgattgggta tcaatcaaaa atcatcaagg atctaccatg acggtttatg
    22681 gaaactctaa tttttctgct ctgccttata gtcaagctca attaaccgaa aagtcacacc
    22741 attatgaatt aataaaagaa aatagaactt ggttcaattt aagttataaa caaaatggta
    22801 tcggctcaca cagttgcggt ccttatttag aagatcgttt ccgttttatg gaagatactt
    22861 ttgactggaa tatagtgatt actttcaaag gagaaaatag atgaaagaaa caaagatcaa
    22921 tcaagtcaaa aaaaaattat ctcgttatca agaagttgtt tatcgaaacc attgcttaaa
    22981 atggtcaaaa aataagctga atgttcgttt taatggatta ttttatcgtt tcgaacagtt
    23041 agaagaagtc tggaaaccgg taacgaattt ccaatcatgt cctgtacagc tcataaatga
    23101 tccaaaagaa acatacgatt tatgtataac acacctttat aaccagcatt tgaaaaatga
    23161 cggattttat ttaaaggtta ctaatgacaa tcaacttacg attgaatcag caaaccttcg
    23221 agggtttcaa tatgctatgg aagccttatt agagagtttt ttttcggtag gagatcaatt
    23281 attattaccg gaattgattc tgaaacatga accatcagtg aaaattcgag gaatcattga
    23341 agggttttat ggtatcccct ggacacatga aatgcgcctc tctctttttt catatatgaa
    23401 agataaccaa ttgaatactt ttatgtatgc ccctaaagat gatgaattat tacgtaaaaa
    23461 atggcgtgaa ctctacgatg cgcaagaatt agacaaattt aaggagcttt tatctgctgc
    23521 tgaggctagc aatatcgatt tttggtactt aattagtcct ggaaatgata ttgatattac
    23581 gtgtgaagaa gacattcaag ttcttctgaa aaagttagaa caactgattg agcttggcgt
    23641 atttcaattt ggtctattaa tggatgatat tgactatcaa ttaaaaggtg ctgctaaacg
    23701 ccgttttcga gagccagcat tcgctcatgc ctatttagtg aatcgagtag aggaatatct
    23761 tagcactcgg ttgtccaatc atgaattagt catttgtcct acagaatatg ataatcgtca
    23821 tggttctcgc tatttagcaa cgttaagtca agaaatacca gaacaattac cgttcttttg
    23881 gactggccca agcacgttag cggcgtcaat ttctacagaa gagctgcagg aaatggcttc
    23941 tgtctatcaa cggccgatgc tgatttggga taatattccg gtaaatgatt atttagagga
    24001 taaagaacta ttgttcatga gtccatatga gaatcgaaca ccgaatcttt ctaaggagag
    24061 ataccaggtt acaggagtag tttcgaatcc aatggctcaa ttagaagctt caaagtttac
    24121 gatcaatagt atggctaatt acttatggaa ctgtgagcgt tttgatcctt tggaaacttg
    24181 gacgtcagtc gttgaaaaag tagttggaag taaactacaa ccagcttatc ttaccttaac
    24241 caatgctttt ccaaatcatt acacaagcag tctgctttca gatgaagaat tactgctagc
    24301 caaagaccca gaatgggtca caaaagaaat ggctgcttta gtccaagcag taaaatggat
    24361 ccagcaagaa caacatacat ctagattgag aacagaattg gagccttggt tacaagcaat
    24421 cacagaaagt tggactttct ggcaagaatg gcaattaaaa aaagatccaa aagaagcaga
    24481 agaatggttg gctaagaaaa aaacacaccg cataggacgt gatttagtaa ctgcccattt
    24541 agagcaaatt atcaaaagtt agatatctta aaaaataaaa agcaagaaaa aggagaacaa
    24601 aatggtcaag agattaatta gtgcaaacta cagtgatgtc aagaaaatga cgtcaaaaga
    24661 gttgaagcaa tccatcaaag cgagtgaagg acgggtgatt gtttgtgaaa cggttgctaa
    24721 tactcttcca caatctggag aaattacgaa tgcagaagtt gcgtcagcat ttggtgcaga
    24781 tttgattctt ttaaatggtt tcgattgtta tcgtcctgca gtttttggac taccaaatgt
    24841 gacgattgag aaggtttttg atctacagca aacgattgaa aacccgattc ctaaattaaa
    24901 agaactagtc ggtcgtcctg tgggaattaa tttagaaccc attgccccta aaacaaatat
    24961 gatgagtgag aaagtagaaa tcagccaagg aagagcaagc tctgttgaaa cgatacaaaa
    25021 agcagaagaa ctaggagtcg attttatttg ctttaccggt aatccaggca ctggagtaac
    25081 caatttagaa attactaaat ccgtaaaaat ggcaaaaaag tatttttcgg gattgattat
    25141 tgctgggaaa atgcatagcg ccggctcaga agagccagtt gtgaataaag aggcgattat
    25201 ttcttatgcg gaagcaggcg cagatatttt actagttcct tcagtagggt ctatcccagg
    25261 ctttttagag caagacctaa ttgaagcggt tcggttggca aaaaaatatg atttgttaac
    25321 gatgtctgca atcggtacta gtcaggaaag tgcccgacca gaaacattgc ggcaattagc
    25381 cattatgaat aaaagttgtg gtgttgattt acaacatatt ggagatgctg gatacggggg
    25441 attggcacca gcagaaaata ttttcgaaac ctcggttgca attagaggaa tgcgacatac
    25501 catcaactgc gttagccgct cgatcaatcg ctaacaaaat taaataaaaa atggttaaat
    25561 tgattattta agtgggaaca tacttgagat atcagctaac ttctgtcact ttaaaaaagg
    25621 gactgtgaca gaagtgaaaa tagacaaaaa atatccgaac aagagactag gatagcagaa
    25681 aaactatcgt tttgcaacga ggaccaactg gaccgtagga gcaattctct tattgttcgg
    25741 atatttcgct tgttcaagga cttatgtctg tagtgccctt ttttggtagg aaaaatggta
    25801 gggaaccata tcatttttaa tgaaaatcaa gcatttcaaa agt
//
LOCUS       DAMEEU010000040        25676 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.041, whole genome shotgun sequence.
ACCESSION   DAMEEU010000040 DAMEEU010000000
VERSION     DAMEEU010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25676
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.041"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            172..516
                     /locus_tag="PB779_001606"
     CDS             172..516
                     /locus_tag="PB779_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HDE0739131.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            517..936
                     /locus_tag="PB779_001607"
     CDS             517..936
                     /locus_tag="PB779_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HDE0739132.1"
                     /translation="MTTKHEEIHNGVIFPAGEKNEAYAQVFTGQSYLNMLVNDPEVSV
                     GVGNVTFEPGCRNHWHVHKDGYQILLVTGGEGWYQEEGKPARRLMAGDVVVTHKGIKH
                     WHGATKDSWFEHLAITAGNSEFLEPVTDEVYEGLENQ"
     gene            complement(1028..1378)
                     /locus_tag="PB779_001608"
     CDS             complement(1028..1378)
                     /locus_tag="PB779_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739133.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1344..2675)
                     /locus_tag="PB779_001609"
     CDS             complement(1344..2675)
                     /locus_tag="PB779_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HDE0739134.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2931..3497
                     /locus_tag="PB779_001610"
     CDS             2931..3497
                     /locus_tag="PB779_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0739135.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3642..3729
                     /locus_tag="PB779_001611"
     tRNA            3642..3729
                     /locus_tag="PB779_001611"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3674..3676,aa:Ser,seq:cga)
     gene            4063..5037
                     /gene="bsh"
                     /locus_tag="PB779_001612"
     CDS             4063..5037
                     /gene="bsh"
                     /locus_tag="PB779_001612"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDE0739136.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
     gene            5362..7257
                     /gene="asnB"
                     /locus_tag="PB779_001613"
     CDS             5362..7257
                     /gene="asnB"
                     /locus_tag="PB779_001613"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HDE0739137.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNEAIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEEWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(7452..7898)
                     /locus_tag="PB779_001614"
     CDS             complement(7452..7898)
                     /locus_tag="PB779_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HDE0739138.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            8126..8275
                     /gene="rpmG"
                     /locus_tag="PB779_001615"
     CDS             8126..8275
                     /gene="rpmG"
                     /locus_tag="PB779_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HDE0739139.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            8363..8881
                     /locus_tag="PB779_001616"
     CDS             8363..8881
                     /locus_tag="PB779_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HDE0739140.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(8958..9914)
                     /locus_tag="PB779_001617"
     CDS             complement(8958..9914)
                     /locus_tag="PB779_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0739141.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            10080..10886
                     /locus_tag="PB779_001618"
     CDS             10080..10886
                     /locus_tag="PB779_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739142.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            10883..11872
                     /locus_tag="PB779_001619"
     CDS             10883..11872
                     /locus_tag="PB779_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDE0739143.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            11869..12873
                     /locus_tag="PB779_001620"
     CDS             11869..12873
                     /locus_tag="PB779_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HDE0739144.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            13005..13547
                     /locus_tag="PB779_001621"
     CDS             13005..13547
                     /locus_tag="PB779_001621"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HDE0739145.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            13567..14265
                     /locus_tag="PB779_001622"
     CDS             13567..14265
                     /locus_tag="PB779_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HDE0739146.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            14286..14498
                     /locus_tag="PB779_001623"
     CDS             14286..14498
                     /locus_tag="PB779_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HDE0739147.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            14498..15460
                     /locus_tag="PB779_001624"
     CDS             14498..15460
                     /locus_tag="PB779_001624"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HDE0739148.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            15478..15873
                     /locus_tag="PB779_001625"
     CDS             15478..15873
                     /locus_tag="PB779_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HDE0739149.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            16036..16401
                     /locus_tag="PB779_001626"
     CDS             16036..16401
                     /locus_tag="PB779_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HDE0739150.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            16398..18209
                     /locus_tag="PB779_001627"
     CDS             16398..18209
                     /locus_tag="PB779_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HDE0739151.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTKENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(18271..18438)
                     /locus_tag="PB779_001628"
     CDS             complement(18271..18438)
                     /locus_tag="PB779_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HDE0739152.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            18686..19675
                     /gene="galE"
                     /locus_tag="PB779_001629"
     CDS             18686..19675
                     /gene="galE"
                     /locus_tag="PB779_001629"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HDE0739153.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            19687..21171
                     /gene="galT"
                     /locus_tag="PB779_001630"
     CDS             19687..21171
                     /gene="galT"
                     /locus_tag="PB779_001630"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HDE0739154.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            21195..22175
                     /locus_tag="PB779_001631"
     CDS             21195..22175
                     /locus_tag="PB779_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0739155.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            22366..23088
                     /gene="tsaB"
                     /locus_tag="PB779_001632"
     CDS             22366..23088
                     /gene="tsaB"
                     /locus_tag="PB779_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HDE0739156.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            23072..23614
                     /gene="rimI"
                     /locus_tag="PB779_001633"
     CDS             23072..23614
                     /gene="rimI"
                     /locus_tag="PB779_001633"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDE0739157.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            23621..24085
                     /gene="rimI"
                     /locus_tag="PB779_001634"
     CDS             23621..24085
                     /gene="rimI"
                     /locus_tag="PB779_001634"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HDE0739158.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            24082..25098
                     /gene="tsaD"
                     /locus_tag="PB779_001635"
     CDS             24082..25098
                     /gene="tsaD"
                     /locus_tag="PB779_001635"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HDE0739159.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
BASE COUNT         8329 a         4400 c         5377 g         7570 t
ORIGIN      
        1 ataaaaaaag cgttagcaac tatgcttaaa aagcatatcg actgaataaa ctaagcattg
       61 gacaggctga aagactacat ttaaaatgaa atgcgaagaa acaatagaaa ataaagttgc
      121 cttagaacca tagttgaatc acctaacagt cgtgaaggga gaataagaga aatggcagaa
      181 aaacaaaccg caggacgaga tcaattagga gattttgcac caaaatttgc agaattgaat
      241 gatgatgttt tatttggaca agtatggtcc agagaagaat tatctgctca tcagcgtagt
      301 atcatcacca tatctgcatt aatttcagga ggaaattttg aacaattgcc agctcatctg
      361 aagattggca agcaaaatgg cattactagt gaagaaatag cagaaatcat tacccattta
      421 gctttttatg taggatggcc aaaagcttgg tcagctttta gtttagcaaa agaaatctat
      481 ttagaagaaa atagcgaaga taagaaagag gcgtaaatga cgacaaaaca cgaagaaata
      541 cacaatggcg tgatttttcc agcaggtgaa aaaaacgaag cttacgctca agtatttacc
      601 gggcaaagct atctgaatat gttagtgaat gatcccgaag tttctgttgg tgtaggtaat
      661 gtaacttttg aaccaggttg tcgcaatcac tggcatgtcc ataaagacgg ctatcaaatc
      721 ttacttgtga ccggaggaga aggctggtat caggaagaag gaaagccagc aagacgatta
      781 atggctggag atgtcgtcgt aacgcacaaa gggattaaac attggcatgg tgcgacaaaa
      841 gacagttggt ttgaacattt ggcgatcact gctggtaatt cagagttttt agaacctgta
      901 acagatgaag tgtatgaagg attggaaaat caataatgtc aagcttgaac agctcctgaa
      961 agtagatttt aatcgaactt tcaggagctg cttttttgat tcagtctttt ataaatagaa
     1021 aatagggtta ataataggaa tgagaagcac gtcgaaagat cttaatattg ataatcggct
     1081 gggcatacat gatttccacg tcatcaatca aactacctaa cagatgataa tcttcccgat
     1141 catgtcgggg attacctaat agttcttgat aatagatttc catactaggg tcccgaggat
     1201 tgttcagcaa atcagcaagt acatctaaat cttctggctg agtttctgcc gtaccctgta
     1261 tctctatgaa aagcccttcc tcagcaaatt ctactccaat acgtatttca gttatttcat
     1321 gggaatataa ataagtaaga agctcatcga tgattctttt tgataattct ttttccaagt
     1381 gtcttttttt cctttctgac agcggtaaag ttatctagta tcggtacaag gatacctgca
     1441 acgaaaccag ttgaaaaacc actgttatat agatttagtc ctccgtgcaa agtgctgacg
     1501 ttatggacaa gagcaatatg tagtacacca gctattacac cgtaaaaact gccgtaaaaa
     1561 ccgcttatgg gcgcgagacc tgtcccaaac acagctgcaa caagcatgcc agtactggtg
     1621 atctcatgaa aagttccaaa caaagaagca ataaatattc cgactagtat cggaaaactg
     1681 ttttttaaat gacaaccaaa agcactgaaa cccaccgcag ataaaatagc accgatgaca
     1741 ggtccattta actgaccgcc aaccagcaaa acataagaag acagcatcag accaactaag
     1801 cctatgttga tcaaagtagc accaatacca gaattagcaa tgaaatcagt tgtcaatttt
     1861 ccagatgaat cgaaaatttc tcgaatcccc aaaagccgaa aggaattata atagaaacca
     1921 attccgactg tcagcgaaaa aaagccaaaa ataatccaaa tgagaggaaa gtgatattca
     1981 ttgaaaacca atgtattttc gacgattgaa tagctgaata acctcaaaac agcagtaaaa
     2041 gtcatcgcaa tcaacccaga ggtgaatcca atattataaa gtgtgaatcc acgatggaaa
     2101 actaaagttt gagcagctaa gggcggaaga agtagaccaa ttgctatgcc agctaaattc
     2161 cccaataaaa tacctatcag taaaggaaaa cgcataccaa aagtgatata actaacgacc
     2221 ggtgataatg cgctaccaaa cagtccgatc atgatgtact gagaaaaagg tttattgaca
     2281 aatacagcgt atagatacac acctaaaatg attgagatag aattataaag gtttttgcca
     2341 aaaaaagaga aaccggtaac tgttagaatc gaagcaaata agggaccgtt taaaatcacc
     2401 ttgtgccgat aagctaaaag cacagaaagt aaggtcaaaa tccctacatt tatgaatgcg
     2461 cttccgaaac cgcctaaagc aaaataatct gtcaaaagat tgcttggcga ggtaagaata
     2521 gttagcaatc cactccaatt atcagtagga gtattagaaa gcaagccaat aaaaagaaaa
     2581 aaaacacctg taaaaccaag ataaaaatac tttcttttct gtgaaacgat tcgtttttga
     2641 ggatgaatat aaataacgtc agtttcgttt tccattacac accttctttt tcattttctt
     2701 taactataac ttgaaatgaa agatttggac aactatcatt taggtcaaaa ctaaaaatgt
     2761 aagggaaccc attgaattta accaaatttt tttaattttg caaaaaaaag ttaaagaaga
     2821 ctgaaaaaaa atttaaaata taacgttttg agtaaaatgt ttgcaaaaaa tgctaaaaat
     2881 agggtacaat aaaacaacat atactgcagt aaagaagtgg gggagtttta atgagaagaa
     2941 aagtctatac caaggatcaa attctaaaag ctgcttatga tgttgttgca aaggaagggt
     3001 ttaaaggatt tactgcgaga aatattgcta aaaagatggg gatttcgaca cagccgattt
     3061 atctggaatt caaaaacatg gaagatttaa aaaatacgtt gctggattct atctttgaac
     3121 aactaaaaga agatgttttc cctattgaac gtactggtga taaaatcatt gatctcggtt
     3181 tgaactatat ctactttgca aaaaagcatc atagtcttta catggcattg tacattgatg
     3241 aacatgggga cggaaagaaa atgcatgatt tttcatacaa ttatttccgt gaaatagtta
     3301 aagaagatga aagatacaat caattatcgg atgaatatgt cgatgctctg catactggta
     3361 catgggtagc agtgactggc ttagcgtcat tgatgtcatc aaacatcatg catccaacag
     3421 aagaacaaat cattgcactg atcaaacgga caattgactc gattttagca ttagataatc
     3481 ctgaaataat cagatagtgt tctatcagta tgaatttgat cggtaagtcc gttggctgca
     3541 aactgtcaat ggactttttt gctaaaaaaa gcgatttctg ttatttatct attagaaata
     3601 ggcttgacat ttcgtgaaaa aagtttaaaa atagtactta cggaaggttg gcagagtggt
     3661 aatgcaccgg actcgaaatc cggcgaaccg gctaataccg gcgcgcaggt tcaaatcctg
     3721 taccttcctt atatcaacga ttagaggttg tgaagaagct gtcctgcatc aagtaataag
     3781 aacggccaaa caaaaatagc ttttcctatt ttttcgtttg attgggctta ttaccgcaga
     3841 tgcaagcttt tgaacaccgt ttgttcggaa taaggggctg tgacaagact tttgtcacag
     3901 ccccttattg ttgtactttt aacctacaat attttttgat tccccctgag tactattttt
     3961 tataaatgct agtaaatcaa tcttctttgg cctttttttg ataaaaaaaa tactagatgt
     4021 aagataaaag tgtaaaaacg atttgtttta ggacgggaaa cgatgtgtac cgcaatcact
     4081 tatgcaacga aagaccatta ttttggaagg aattttgatt atgagatgtc ttataatgaa
     4141 gtggtcacta ttactccaag aaattatcgt ttcgatttta gaaaggtaaa aaatttagat
     4201 aaacattatg caatgatagg aatagcagct ggggtatcca actatccact ctattatgag
     4261 gctacaaatg aaaaagggtt gagtatggca ggactgaatt ttcctggcaa tgctgattat
     4321 aaagaattac aagaaggaaa agataacgtt gcaccatttg agtttattcc atggatacta
     4381 gggcaatgct caaccataga cgaagctaaa gaattattgg ctactatcaa tctagtcaat
     4441 atcgatttta gtgaaaaact acccttgtca cctttacact ggttattagc tgataaagaa
     4501 aaatcgatag taattgaaag tatgaaagat ggacttcatt tatatgataa tcctgtcggt
     4561 gtgttgacaa ataatccgcc atttgattat caattattta atctgaacaa ttatcgctcg
     4621 ctatcaaatg gaacaccaga aaatcatttt tcaaaccaga tcagcttgaa tgtttatagt
     4681 cgtgggatgg gaggattggg cttacctgga gatctctctt ctgtttctcg atttgtaaaa
     4741 gccacattta ctaaaatgaa tgctgcatca ggtgattcag aatctgaaag tatcagtcaa
     4801 ttttttcata tactaggctc agtcgagcaa caaaaaggag tatgcgatac tggagaaaga
     4861 aaatacgaat atacgattta ttcttcttgc tgtaacgttg ataaagggat ttattattat
     4921 cgtacgtatg aagacagtca aattactgct gtaaatatga ataaagaaga cttggatcgt
     4981 catgaattgg tcagttatcc agtcataaaa gagcaacaga taaactatgt caattaatta
     5041 atgaatagat ccgtttggta tcatattttc tgatacagtc ataattagac acgatcttta
     5101 ggtcgtgtct ttttttgctg gtttttttgg aaatagcatc cactaatatt tttttaacac
     5161 gaagagaata aggtagcctc aaaaaagaaa acatggtaaa ttagatattg ggactttatt
     5221 ttctgtaaaa acagaaactt tcatcttttg ttttcacgtg acgaaattgt aagagagaaa
     5281 atattcgtcc gctatttatt ctatgataag atgcatatga atgaaataaa cagtaatttt
     5341 atattaggat gtgaaagtta aatgtgcggt attgtaggtt ttgttaacga caaggacaac
     5401 aaaaaaacaa ttattaatac aatgatggat cgaatcgttc accgtggacc taatagttca
     5461 ggagaatata tcgataaaca tgttgcttta ggattcagaa gattaagtat tattgactta
     5521 gagggcggta ctcagcctat ttacaatgaa gatcggacaa agatcattat ttttaatggc
     5581 gaaatctata attaccagcc tttgagagaa gaattgattg cagctggcca cgtttttcaa
     5641 acacatgcag atacagaagt ccttttgcat ggttacgaag aatggggaac agaattattg
     5701 caaaagatcc gcggaatgtt tgcttttgct atttgggata atgaaaagaa tgagttattc
     5761 ggtgcaagag accactttgg gatcaaacca tattattatg cagaaatgaa cggaacattt
     5821 atgtttggtt cagaaatcaa aagttttctg cctcatcctg attttaacaa agaattgaac
     5881 aaagaagcgt tgaaacctta tatgactttc caatattctc cattaaacgg cgaaacattc
     5941 ttcaaagatg tctatcgttt gcctgaaggc cattattata cgtataaaga tggaaaaata
     6001 gacattcagc aatattggga tgcagatttt gaaacaaaag aaacgcattc ccgacaagaa
     6061 tggatcgaaa aaatcgacga aaccgttcaa gcttctattg aagcacatac ggtcagtgat
     6121 gtagaagttg gttctttctt atccagcggg gttgattcca gttatgtaac ctctgtattg
     6181 aaaccagatc attctttctc aatcgggttt gatgataaaa cctataatga agcgattgaa
     6241 gccagaaaac taaccgaact attggactta gataatacag cagcagtgat cgacggagac
     6301 atgtcgttca aagcattccc tttgatccag tatcacttag atgaacctga ttcaaatcct
     6361 tcttgcgtac ctttgtactt tttagcaaat cttgcttcac aaagtgtgcg ggtagtccaa
     6421 tctggagaag gggcggatga actgtttgcg ggataccaaa cgtatggatt ccatacgaat
     6481 tcaaaattca tccgtgtgat tgctcaagga ttgaaaaaat taccaaaagg aacacgctat
     6541 aatttaggac gtaaaatcgg aaaaatgaaa aatttccatg gacggatcca tttatatgaa
     6601 tcacttgctc ctgcaaaaga atattttatc ggtcatgctc gagtgttcga agaatcagaa
     6661 gcatcagaag tgttaacacc aaaatatcaa acagcaccat ctgtggatga aatcatgact
     6721 gttcattacg agaaaacaga aggaatcaaa gatgaagtca ataagatgca atatgtcgat
     6781 cttcatcaat ggatgccaaa agatatcttg ttaaaggcag ataaactttc tatggcaagt
     6841 tctttggaag tccgagtacc tttattggat atcgaagtca tgaaattggc tcaacaaata
     6901 ccaagtaagt ttttattgaa tcaaaacaac acaaaagata ttttcagaca agctgcgaac
     6961 aaacatcttc cggaagaatg gtcgaatcgt gtgaaattag gattccctgt gccaatcaaa
     7021 gcttggttga aagaagaaca cggctacgaa caagtcaaag cattattcga agcagatttt
     7081 gcaaaagaat tttttgatca agaaaaaatc atgaagttgc tagatgacca tcacgaagga
     7141 cgtaaagaag agcaaagaaa aatctggaca atcttcagtt tcttgacatg gtataaagtc
     7201 tactttgtag atgaaacgat tccgcaagca gaagcaatcg actatgtgac tgtttgatga
     7261 aaatcaaata tcaataaaaa agaggttttc tcctaccgtt taacactgag tgataagaaa
     7321 caatttcaaa aaacagctct tcccgtttta tagatattat gacttatggt tcggagttgg
     7381 cagaggaaca ccattgtttc gaacataagg gggttgtgac acgattttcg tcacaacccc
     7441 tttacatatg ttcaataatc gatttctttt tcttttgtcc catctttttt ataaatgaac
     7501 aaagttgatt ctttgttttg tgctacttgc tttccttttt cgattgcttc tttttttgta
     7561 tcaaaatggt tgcttgcctt ttttgcccct ttagatttca cgatccattg ttcttcctca
     7621 tattctacga tcacatctga atcaagcagt tttccagcac gaggattcgt atcgtgttca
     7681 tccgtcttgc ttggattttt ttctttttcg aaagttcgtt tttctgattc actagcatct
     7741 tcataccatt tttttgcttg atcaatggca attgggatcg cacggttatc agggtaccct
     7801 tcatctaata atgcatttgc gatgtcgatt gctttttttc ttgtcaattt atctaagttt
     7861 ttcattgatg caggaaagtc cttcatgttc catggcatat tagtatcccc ctttattaaa
     7921 aaacataatc tatataaaca agtgtaaggg tatttataca aaaagaaaaa gattttgttt
     7981 gagaagtaaa accgttgtat ttatcgtcaa gtagttttac ttaacaaaat cgtgaaaaac
     8041 actagcaatc tagaaaaaat catggtaaga taatcaagtc tgagagtcat cttagaggat
     8101 tcttgtaaaa atgggaggga aaaacatgcg cgtaaacatc actttagagt gtacttcttg
     8161 taaagaacgt aactatctaa caagcaaaaa caaacgtaac aatcctgatc gtttggaaaa
     8221 acaaaaatat tgcccacgcg aacgcaaagt tactttgcac cgtgaaacaa aataatgttt
     8281 ttaaagttct caattccttg ctggtcaaag aattgagact ttttttatct caaaacatct
     8341 aaaatcataa ggagcggata atatgtttat ttccatgtgg gcacaagata aaaatggtct
     8401 gatcggcaaa aatggtttgt taccatggcg attgccaaat gatatgcgtt tctttcgcga
     8461 acacacaatg gatcgaattt tagtgatggg aagaaagacc tatgaaggaa tgggggatct
     8521 ttcacttcct tatcgccata tcatcgtgtt gacaacgcaa ccaaattttc gcacgaaaga
     8581 aaatgcggaa gtaatgcatt cgatcgatga acttttgtcg tatagtcaaa cgatctcaga
     8641 agatatctat gtttcgggtg gtagtcggat ttttcaagaa cttcttcctt acactggtcg
     8701 gatctggcga acattgatcg atagcacgtt tgaaggcgat acgtatattg ggaatattga
     8761 tttttcagac ttcgccctta tagaggagta tgaggggata acggatcaag aaaatctata
     8821 tgcccatcgt tttcaaaaat gggaaagagt aaaaaatagg gttgcttcaa aagaagaata
     8881 aaatctatgc gtctagtttg ttaataagaa aaaaagcatc tcacgactaa tcgtgaagat
     8941 gcttttttta gttaaaatca atttagtttt tctttgatat cattgaccat ttcctgactg
     9001 gcaataggtc cgttatatag ccaactagat tcaggtccga attgcagtac atgattgtct
     9061 gtcactgctt ttagattctt ccagcttggt tcattgaaca tggcagcatc tttgtcactg
     9121 ttcacaagga tgatgtagtc agcatctaat tcagctagct tttcagagga aacagcagac
     9181 cagtcagaag tggctttttt ggagacctct tccactagat caggaacacc aaattccaga
     9241 tcgtcgtata cgattcttcc acttgaccga tttttgctga ccataaaggc tgagttgttg
     9301 gtcacccaca acactgcagc tgtcttgttc tcgattttat ctgctagttc ttctcgagtt
     9361 ttcttgatgg atttttgata atcggaaatg attttttctg cctctttttc ttttgccaaa
     9421 gctttgccga catcttttag ttgttcttcc catgtgacat ctgttccgtt ttttacaaca
     9481 taagttggcg cgattttgct atattgttcg tatttcccgc cttcgacagt agcggaagaa
     9541 gaaatcaaca gcaaatcagg ctcaaagctt aacactttct cataaggaag gtcataagaa
     9601 atcgttggga catcctttaa atcatcttgc agataatctt gaatggaacc actgccaaca
     9661 gtccactggg cgataggttt ttcccctagt gcaatcagat agtcttctaa gtaactgccg
     9721 atgatccgtt tgggcgcgtt tggaatctct actttatgtc caagtgtatc tgtgactgta
     9781 tgagtactat tggatgaagt cgtcgaattg gcagttgtag ctgtttcttt atctgaagag
     9841 ggggagcaag cgctcagtac tccagccagc agcaatatgc tagataatgt gaatactttt
     9901 gtttttaatt tcatttcttt cctcctaaca taattgagaa tctttctcat tggttattat
     9961 tcctgatatt tcgaacgctg tcaaccgctt catttggcta tagatatgaa agtagcgctt
    10021 gacgaaatgt tgaaacagcg tcataattga gaatgatttt cagcgaaagg atgggtgaaa
    10081 tgacgagatt aagagcagct gacattgcag ccggctacga aaacaaaaaa atcattgaaa
    10141 acatgtctgt tacgattcct gaagggaaaa tcactagttt gattgggcca aatggaagtg
    10201 gaaaatctac tttattgaaa agttttaccc gtatactacc tgtgaaatca ggaaagatca
    10261 ttgtcaataa ctctgatatc tctacataca gttcaaaaga acttgcaaaa aaaattgcat
    10321 tattagcaca aactagtgaa caccctacag gtatgacagt agaagaagta gtatcttacg
    10381 gacgataccc ttatcaaaaa ctgttcagtg gcatggacac gcaagatcat gaagcaattg
    10441 agtgggcgtt ggatgctaca ggtctagctg gatttcgtat gcgggatatc gcaacgctgt
    10501 ctggtggaca aacccagcgt gtctggatcg ctatggcgct tgctcaggaa acagatatct
    10561 tgatcttgga tgaaccgaca acatttttag atccggcaca ccaattagag atcctacagt
    10621 tattgactga aatcaatcaa atgaaacaaa caacgatctt gatgtcgatt catgacatta
    10681 atcatgcttc acgtttttca gattatttat tagcaatgaa aaacggtaag ttgatcacag
    10741 aaggtacacc tgaagaagtg atcacaaaag agtgtatgaa aaaaatattt gagattgatg
    10801 caacgattgt cacgcttcca agaacaaata aaccagtttt tctaacctat gatttgttgc
    10861 caaaagagca ggaggatcaa ttatgaggac tatgaagaaa aatagactcc tgcttttggt
    10921 ctgttttgtt cttttgatta ttttttttgt tgctctttca aatggcgcag cgactgtggg
    10981 aaaagcagat ttttggcagg cgttgtttga ttttgataga tcaaaacaaa gtcaccaaat
    11041 catacgaaat attcgtttgc ctcgtgtggc gggagcattt cttgtaggga gttgttttgc
    11101 attgagcggt gcattgatgc aaggagtgac aagaaatcct ttagcagatt caggcttact
    11161 aggaatcaac gcgggtgctt cgttggcaat ggcccttagt tttgcttttt ggcctaaagc
    11221 ttctgatttt tctgtgtttc taatgtcatt ggcaggttct tttgctgtaa ctttgctcgt
    11281 atttggtttt ttgcagtttt cgaaaatggg catgaatcct ttacagctga ttttagctgg
    11341 cgtagctatt agttcttttt ttactgctat cagccaagca cttacccaat tctttaatct
    11401 gcagcaggat cttgcttttt ggtttgtagg cggagctgcc aatatcacat ggaaacaatt
    11461 agcagtattg tttcctttat atatacttgc tgttttggtt tctttttcat taggaaaagc
    11521 aatatctttg attcatttga gtgaaacaca tgcattagct cttggaagtc atcctaaacg
    11581 aacgcggttg attgttttct gtctagttgc agtgttagca gccattgccg tttcgttagt
    11641 cggacctgtt tcatttattg ggctgttggt tccgccagtt gttcgcggaa tggttggaac
    11701 ggactatcgt tatgttctac ctgtctcttt tttagttggc ggtggattgg ttatgttggc
    11761 ggattttaca gcgaggatga tcaatccccc ttttgaaaca ccttttggat tagtcattgc
    11821 attgattggc gttccgtttt tactgataca agtaaggagg gaacaacggt gaaaaaaata
    11881 tattggacgt tctatttctt gctttttgta cttgtcatcc tgtctatagg tagtttaatg
    11941 attggtacgc cttttattta cctggatcag ctttttgcca cgttcatagg gaaagaatca
    12001 tcttctttgg cgctgattgt tagagaattt cgagttcctc gattactgat cagtttatta
    12061 gcaggagctt gtcttggcgt ttctggttat atcttgcaag gagtaacaag aaatgaattg
    12121 gcagattcta gtatattggg cattaatgcc ggagcaggat ttttagtgat gctttattta
    12181 ggtttctttt cgcactattc gctgccgttt ctattgctag ttgtagcctt tctaggtggt
    12241 gttttagctg cttgctgtgt ctatcttgcg gcctatgatc gaaatggctt tttgggtatg
    12301 aatcgaatct tattgtccgg tattgccgtt aatgccggcc tttctgcatt aacattgcta
    12361 tgcacgatcc aattatctaa ggaaaattat ggatttgtga atgcatggtt agcgggatca
    12421 atctggggtg cgagctggcc ttatgtttgg gcattgcttc catgggcggt tatcttaatt
    12481 ccgctaggag gactttatgc acagaggatt gtattgctat catttggtca agaacgcgcg
    12541 caaggattag gccttaacgt ggctaaaagt caaaaaatcc ttttgttgtt agctgttgct
    12601 ttggcaagcg gtagtgtagc ggtgacaggt agtttatctt ttgtaggact actagctcct
    12661 catgctgcga agctagtcgt acgtaaagaa aataactgga cctttgttct gagcggtttg
    12721 ttcggttcca tttttctgct tagtgcagat atggttgcta gagtgattct actaagtggg
    12781 gaagtaccta caggaatttt gattgccctt tttggtgcgc catattttct gtatgcactt
    12841 tttatcagac aaaaacacgc gctgaacagt tgaaattcat taaaaaagga aggccaatca
    12901 tttctaggtc ttctttttat tctatttatg catttatttg aaagttcgat tgctattttt
    12961 ctttttttcc tataccattt tatgagagaa ggaagggtga gtttttggac caattgaaag
    13021 taagattacg ccggaaagga atcgaaaagc tgaaaaatct ggccaaaagt ggcaagaaaa
    13081 aggaaaaaga acagcgaatc tataaacagc tattcgccag cgagtactgg aagtcagcaa
    13141 aagtgatagg gacgacttta tcgaatgaat ttgaactgga tacacagccg gttatccaac
    13201 gagcagaaaa agaacaaaag aaaatagttg tacctaaaac tttgccgaaa cgtcagatgg
    13261 cgttttatga aatggatgaa cagtccgttc ttgtacgttc gagttttggt gttcttgagc
    13321 cacaatcaga gaagctctat ttgccggaga tgatcgatct cctcattgta ccaggtatta
    13381 tctacaatag agccggttat cgaatcggtt ttggcggtgg ttattacgac cggtatttaa
    13441 ataattttca taaaaaaaca tgtagccttg tttttcgtga acaattgaat gaacaatggc
    13501 aaccggagag ctttgatcag aagatccaac aattgtttat tgactaaaat gaaatgggag
    13561 gttttcatga attatcaaca gcaaataaaa ttgcgtgcat ggttaagacg accgttatgg
    13621 acctatgctt ttttagggat acagacagcg gtcttcctca tgatggaatt atttccgcga
    13681 cttgagatcc cttattatgc cggaatgtat ggtccttatc ttgttcactt caatgaatgg
    13741 tggcgtttag tgacaccaat cttcatccat tttggactga tgcatttcgt aatgaactca
    13801 ctgatactgt attttatggg gcagcaaatc gaggcaatct atggccattg gcgttttttc
    13861 ttgatttata tgttcagcgg gataatggga aatacagcaa gctttgcttt taacgaagcg
    13921 aatgttctgt ctggtggtgc aagtacttcg atattcggtt tgttcggtgc gttgtttatc
    13981 ttagggtttc attttaaaca taacccagcg atccagcagc tagtcagaca ttttctttta
    14041 tttattgtgt tgacatttgt ttttggtctt ctggatacct ctgtagatgt ttggggacat
    14101 gtcggtgggc taattggcgg attagtgtta gggaatgttt tgggtctacc gaaacaacag
    14161 acaagctatt cgatacacca aaggattctt tctacactag tttttgtatt tctttttgta
    14221 atatgtattt tactgggttt aaaaaaatat ggtttacttg tataatatga aggaagtgct
    14281 taaagatgga gagcttatat gatgtacagc agctgttcaa aaaatttggc atctttatct
    14341 atgtgggtgc acgcatctat gacattgaat taatgactat cgaattgcgt aatctgtatg
    14401 atagccgttt gattgatcat gatacataca tgacagcgtg gcgcatatta aaaagagagc
    14461 accgaattga agaaagccga aagaaaggaa atttgtaatg gacaagaaga ttattgggat
    14521 tgatttaggt ggaacaacag caaaatttgc aattttaaca ccagaaggag agattcagca
    14581 aaaatggagc atcgatacca atattttgga tgatggtaag catatcgttc ctgaaatcat
    14641 tgaatcaatc aatcatcgtt tgaatttata taatatgaaa gccgaagact ttatcggaat
    14701 cggcatgggt accccaggaa gcgtggacag cgaagctgga acggttattg gtgcgtataa
    14761 cttaaactgg acagaagttc aatttgtgaa aaaactgatc gaggcaggaa caggaatcaa
    14821 attcgctatc gataatgacg cgaatgttgc tgctttaggt gaacgatgga aaggtgctgg
    14881 agaaaacgat ccagacgttg tattcgttac tctaggaaca ggtgttggcg gaggtatcgt
    14941 tgctggcgga aatttgattc acggcgtgag cggagctgga ggagaaatcg gacatatcac
    15001 tgtggatcct gaagggttcg aatgtacttg cggtaaacgc ggatgtttag aaactgtatc
    15061 tagcgctaca ggtgtggtac gcctaggtcg tttcttggca gaagaatacg caggggattc
    15121 aaaactgaaa gcaatgctag acaacggaga agaagtaaca agtaaagata tctttgaaat
    15181 ggctcaagaa gacgatccgt ttgcattgat ggttgttgat cgcgtatgct tctacttagg
    15241 tttagcttgc ggaaacttgg ggaatacatt aaatccgtca agtatcgtgt taggtggagg
    15301 agtatcggca gcaggagaat ttttacgtag ccgtgtagag aaatatttta aagaatttac
    15361 tttcccgcaa gtaagagaat caacaaaaat caaattagca gagcttggta atgaagctgg
    15421 tgtcattggt gctgcctcat tagccttgaa atttgcttaa aaaaacggag gcattacatg
    15481 gttttatggg taattaatat cattttgcta ttgattgtgc ttgcaatcat cctttgggaa
    15541 gtctatctac gagtaatggc caaacgttca gcaacgactt tgacagaaga agaatttcga
    15601 gaaggaatga gaaaagcaca agtaatcgat gttcgcgaaa aagatgtgtt tgatgctggg
    15661 catattttag gtgcaagaaa catcccttac actgttttga aagattcatt aggatctatt
    15721 cgaaaagacc agcctgtcta tatttacgat caaaagaaaa gtttgagcat ccgtacagca
    15781 aataaattac gtaaagcagg ttatcaagag atttatttac ttaagggtgg atatgacgga
    15841 tggtctggaa aaatcaaaag taaaaaagta taaaacagat gattgtatga cagctttaaa
    15901 aaccgaatca atcattagat tttgaccaag atcacatgaa cggcgcaatg gatagttgtg
    15961 ccgttcattt tttttatttt gtgctattat ctacatatat aagctaagcg aaaaggtaga
    16021 aagaaggaaa caactatgat caaattaaaa cgtgtttacc ttgatgctga aaaagaggat
    16081 ggctatagaa tactcgtgga tagattctgg ccacgaggaa tttcaaaaga aaaagcgcag
    16141 ttagatctgt ggttgaaaga aattgcacct agtaatgaag cacgcaaaac ttttgaccat
    16201 gtaccagaac gatttgcttc atttgcaaag aaataccagc aagaattgat tttcgaagaa
    16261 gaaaagaagc aagctatttt taaactcagt caacttatga aagaacatcc agtcattact
    16321 tttgtttatg gtgcaaaaaa tgaacatcag aaccatgctg ttttattgaa aaaatttatc
    16381 gaaatggagg catgcaaatg aaaataggga tcattggtgc cggacctaga ggattaagtg
    16441 tagcagaaag gattctccat aataatcagg acagacattc tcttgaactt tttcttttcg
    16501 atcccaatgg tcctggaggt cgagtttggc ggttgaatca gccaccggag ttattaatga
    16561 attctgtttc tcaacaagtg acgcttttta cagatgaaac attgtccagt ggaggattgg
    16621 taacacaggg acccaacttg tttcaatgga gtaaaggacc tgctacagat tatatcgaac
    16681 agacggtaac caaaaataag caactaatta tagaagaaat caatcgtctg gaaaaagatc
    16741 agcaatctac tcgatgttta tacggactct atcaacgctg gtttttctca aagttgcaag
    16801 aagaatttcc agcttctatt cagtttgttt attctttagt aaaaaaagta agcaaaagaa
    16861 aagatggtta tcttttacag acagatcagc aaagctattc tatcgatcag cttgttttag
    16921 caagcggtca ctgggaaaat gatgagacag aagaagaaag agtgtgggta gactacgcaa
    16981 agaaaaatgt tttactgtat cagcttcctt ctaatcctgc agatgtagat ctttcgaaga
    17041 taccgcctaa agaaaatgtc tttttaagag gtctaggctt aagttttttt gattatgtcg
    17101 gattgtttac agtatcaaga ggagggcgct tcgagaacga aaagggaaaa ctggtctatc
    17161 atccatcagg caaggaaccg attgtataca gtggatcaag aagggggctc ccttattacc
    17221 ctcgaggaag aaatcaaaag caaggcggag caatggcatg gccacggtta ctaacaaaag
    17281 aaaacctgga gcaatggcat cagtcgggat ttttgactgg cgaaacattt tttgactatc
    17341 tgaaaaaaga cgttgagttg ttttattaca agaaaatcat cgaagaatat cacttgccga
    17401 ttccaaagaa aaattttgag catgattttc tctccctctc ttcagaggag tgtctcggaa
    17461 agcatccagc actaatccct tatagatggg attggtcgta tttagaaact cctcttgcct
    17521 atcagaatga gcccttttca gaagctagcc gaatatttat tgaagggcag ataaaagaag
    17581 cggaaaaagg caattgcaca ggagcatttg cttcaacatt tgatgcatta aaagactggc
    17641 gtgatccaat ccggcaggct attgaatggc acgttttttc tgctaaggaa tacaaagaaa
    17701 tactatgggg atggtttact catctaaata gctttttaac gatcggtccg ccaatcattc
    17761 ggacgaaaga attagcagca ctgatagatg cgggtatttt tcatttgatc gaaccgccat
    17821 ttgatattca gcaaaagcac aaccgctatg ttatttctct acaagataaa gaaatcagca
    17881 gtcgctattt gattgaagct cgattgccac aaacaagctt ttctcgttca agtaatcctg
    17941 tcataaaaaa tttgaaggaa aacaaacttg ttcgcccttt ttcattttca gataatacag
    18001 gaagttatca ttcagaagct atagatgttg agcgaggtac gaatcgcgtg attgatgctt
    18061 caggggaaat ccagtctgac ttttattgct atggaatacc tgttgaaggt gtggattggc
    18121 taactgcagc agtagctaga ccttatacag atccatggaa tctgagacag gcagataaaa
    18181 tagcacaact tatattgact gacaaataaa aatacgcatg atgacttatc tgttttttag
    18241 aaagtcttca tgcgtatttt taaataatta ttaacgagaa acgcgtttac gcattgcttt
    18301 tttacggttt tcttcgatca ttgcttcttt ttcgtcaatt ggatcgatca ctgttttttt
    18361 cacagaagca accaaaccag caacggcagc ggctgttgcc agacttccta ctaatattcc
    18421 agatacaaat tttttcattg aatccacctc atttattatt tgttatatct attatggaac
    18481 aaaagagaaa aaaaggctag ttttacgttt gtttgtaaac ctttgcaaaa aatccttgaa
    18541 aatgtttact aaatgtttta ttataaattt accatatgaa tttacgaaat tttactttgt
    18601 ttgttttcac cataaaagta aacttcgttt tttaaattat atagaatcaa caaacacaat
    18661 tttactaatc aaaggagtgt tttttatgac aattttagta ctaggcggag ccggttatat
    18721 cggttcgcac gctgtagacc agctagttca aaaggggtat caagtagctg tggtagataa
    18781 tttgctcaca ggtcacaaac aagcagtaca tccagatgct catttttatg aaggagacat
    18841 ccgggataaa gaatttctac gttccgtatt tgaaaaggaa ccgattgaag gagtaatcca
    18901 ttttgctgca agctctttag taggagaatc tgtcgaaaaa ccattgatgt atttcaacaa
    18961 caacgtatac ggtatgcaaa tcttacttga agtcatgcac gagttcaacg tgaataaaat
    19021 cgtattctct tctactgcag caacttatgg agagccgaaa gagtctccaa tcacagaaga
    19081 tacaccagct aatcctaaaa atccgtatgg tgaaagtaaa ttgatgatgg aaaaaatgat
    19141 gaagtggtgt gaccaagcat atggcatgcg ctatgtcgct ttgcgctact tcaatgtagc
    19201 cggagcaaaa gcagatgcat ctatcggaga agatcataca ccagaaacgc atcttgtccc
    19261 aatcatttta caagtagctc ttggtcaaag aaaagccttg gctgtttatg gagacgatta
    19321 tgatacacca gatggaacat gtatcagaga ttatgttcaa gtagaagatt tgattgctgc
    19381 acatatttta gctttggaat acttgaaaga aggaaatgaa agcaacttct tcaatttagg
    19441 cagcagcaaa ggatactcag tcaaggaaat gctagaagca gctagagaag tgacaggaaa
    19501 agaaattcca gcagaaatag caccaagaag agctggagat cctagccgat tagtcgcttc
    19561 aagtgaaaaa gcgagagaga ttctgggctg gaaacctgaa tacacagata tcaaagcgat
    19621 tatcaaaaca gcatgggatt ggcatgtcag ccatccaaat ggttatgaag aataggggaa
    19681 tgagatatgt caatcagtca aacgatttgt gattttgcca cacttgcgat cgaagctggc
    19741 ggatggatgg aaatggaccg cttatattta cagaatcgtc ttttagggat ggtaggagaa
    19801 gatgctctag aaagcattga agtaagacca gttaaggaag aatctgtaga cttattggat
    19861 cagcttgtcg ctaaggcaag agaaaatggt gttctttcag aattgccagc agaacaagag
    19921 atttttgaag cgcaattaat ggattttctc acaccgccac cttcagtcgt caatgcattc
    19981 tttgcacagc actattcgaa aagcccagag gaagcaactg agtatttctt taatttaagt
    20041 aagaaaaatg actacatcaa aacaagagcc atcgcaaaaa acatcaaatt tccggcagag
    20101 tcggagtatg gtgaactgga aatcacaatc aatttatcta agccagaaaa agatccaaaa
    20161 caaatcgcag cagaacgcga ggcggtaaaa gtagactatc ctacctgcat gctttgcatg
    20221 gaaaacgaag gatatagagg tcgcttgaac tatccagccc gcaccaatca ccggattatt
    20281 cgaatgaatc tagacggtga aagctgggga ttccaatatt ccccttatgc ttattacaat
    20341 gaacattcga tcattttatc agaacaacac cgcccgatga aaatcacaaa ggaaacattt
    20401 gctagactgc ttcggattac tgaagtcttg cctcattact ttgttggttc gaatgctgac
    20461 ttaccaattg ttggaggatc gattctttct catgatcatt atcaggcagg acgtcatgaa
    20521 tttcctatgg caaaagcacc gatagaaaaa cttatcaaac tagaagatta tccgcaagtc
    20581 atcgcaggag tcgtgaaatg gccgatgtct gtgatccgtt tgcaatcaac agagaaaaac
    20641 ttgcttattg aagcagctaa ctcagtattg gaaaaatgga aagcatattc ggatgaaaca
    20701 gtatctatca gagctttttc agcagatggt acaccacacc atacgattac gccaattgca
    20761 cgaagaaggg acaattactt tgagttggac cttgtccttc gagacaacaa tgtttcagaa
    20821 gaacatcctg atgggatttt tcatccacat aaagatgtcc aacatatcaa aaaggagaac
    20881 attgggttga tcgaagtaat ggggcttgct gttttaccac ctcgtttgaa accagaacta
    20941 gtagaagtag agcatttctt attaggagaa gaaaaccaga tggctgaata tcatcgtccg
    21001 tgggcagaac aattaaaaaa agaacatcct gatttgacga aagatacggt caccgatgtc
    21061 gtacaaaaat ctgtaggtca ggtttttgca cgtgtactgg aagacgctgg agtattcaag
    21121 cgagatgaaa aaggacaggc agcgtttgaa cgatttactg cgattttata aacgtaaaaa
    21181 aggaggagag acaaatggca acaattaaag acattgcgca gttggcagga gtttctcctg
    21241 ctactgtttc aagagttctc aactatgatc ctgatctttc cgttggctta gccacaaagc
    21301 aaaaaatttt tgaagcagca gaacgcttaa attatacgaa acatcgtaaa aatgcagcaa
    21361 atactaagca aacgcttcgc ctgatccagt ggtacgacga tacggaagag cttgaagatc
    21421 tttattattt atctattcgc ctaggaatcg aaaaaaaggc agaagaagca aacgttactt
    21481 tattgaaaga aacgtgggat tccattagtg atcttccggc agatggaacg atcgcactag
    21541 gaaaattcga cgaagctcag ttattagaaa tgaaaggatc ccaaaatgcc ttgcttttgg
    21601 tagattctga cggcacttct caaggaatcg actctctagt tgtcgacttt aagtcaagtg
    21661 ttcaaaaagt cattgaacac tttgtctccc ataaagcgca acatatcgct atgcttgctg
    21721 gaacagaata tacgaagaaa aaccatcagc ggctaaaaga tcccagaatt atggcatttc
    21781 aacaagtttt ggcagaaaaa ggctacgacg aaggtccaat tatcgaagca gatttttctg
    21841 tcgagtcagg atatcaagca gtgaagcagt atttaaaaac gaatccgcat gttcctgatg
    21901 cgctttttgc agctaatgat gcattagcga ttggcgcact gaaagcgatt caagaaaaag
    21961 gtttagtggt accagaagat atttctgtga tgggcttcaa tgatgtcagt gtagcgaaat
    22021 atgtaacgcc ctcgctttct actgtaaaag tttataccga atggatggga gagctagcag
    22081 tggagacgat tcttcaatta agtaattcca aagcaccggt ttcaagaaag attattgtgg
    22141 aaacagagtt gattattcga gaatcaacga aataaaagat ggaaaagctg tgggaaaatg
    22201 gagtgatacc gcagcttttt tgtgtttcag gaaggggcaa aatttgcccg ccagcagata
    22261 atcatgtatt attgtactag ttttgccttt ggtattttca tcctcagaat aaaaaagtat
    22321 gctacaatgg aaggcgagaa tgtcatagca gaaaggatca aatatatgat tacattagga
    22381 atagatactg caaaccaaac tttggcgatc ggtgtggtag aagacgaaca aattcttgga
    22441 caaatacaaa caaatatcaa acgcaaccac agtgtaacac tgatgcctgc aatcgaccaa
    22501 ttgtttgcag atcttcaaat aagtccaaaa gacattgacc gaatcgcggt ttctgatggt
    22561 cccggttctt atacagggct tcgtataggt gtaacgacag caaaaacgat tgcttataca
    22621 ttagataaag agctagtagg agtatctagt ctgaaaacca tcgcggctaa ttgcatcggt
    22681 gtggataata ttattgtgcc catgtttgat gctcgaagaa aaaatgtata cgctggggca
    22741 taccgctgga aagaaaatag attagaaact gtacttgaag atgtacatat ttctgcttct
    22801 gatttgttca cacaactaca aaagctgaat gaagctattt atttcgtcgg gagtgattgt
    22861 cacaaattct tctctgaaat aaaggaaata ttgcctagtg cgatgattaa tacagttcca
    22921 gcatgggata ttccaagtgg tgtaactgtg gctcaattag gtgctttagt tgaaccagtt
    22981 gcagagaaac aagcttttct tcctcgctat ttaaaacgag tagaagcaga agaaaaatgg
    23041 ttggagacgc acacacctgg agacgaaagt tatgttgaaa aaatttagag cgtatgccag
    23101 aagctttttt caagataaaa tgatttatac agaaaaaaca gtcgaacaaa tcgatcgtcg
    23161 ttacgtacta agagaattga ctacagaaga tatcaaagag ctgctggatg tcgaacgaga
    23221 agtctataat ggcgaattgc catggacaaa aagtgccttt atatcagaat tgaagtcacc
    23281 gcttcctcat ctatatctag gtatctttga taatggaaga atgattggtt ttatcggttc
    23341 aagagcgttc ggtttagatt gccatatcac gaatattgcc gttcgaccgg catatcagcg
    23401 taaacgaatc ggttcgctgc ttattgacga aatcgagaac tttgctataa tgaatcgctg
    23461 tgagacgatg tcattagaag tgcgtatgag taatcaagat gcacaaagac tttatcggaa
    23521 attggggttt caagcaacaa cgatcaaaaa aagatattac actgaaacaa aagaagatgc
    23581 gttggatatg ataaaacttt tagaaaatga gtgagattag ttgatttgca gaaaaaaaga
    23641 ttttgatgaa gcgtacttgg cagaatgcgt atggatgatt agcgaaaatg cttatccaca
    23701 tggttcacct tggacgaaaa tgcagttttt ggcagacatc caacagcctc actctgatta
    23761 tctgctttta gctgaagata accagatctg tggctttatt ggatactcga aagtaataga
    23821 tgaagtcgag atcacaaata ttgctgttgc agtttcagaa caaggaaaag ggcatgcacg
    23881 gcatttgtta caattactga ttacggaaca aataaaagat tcgctgcatg tttttttaga
    23941 agtacgtcta tctaatgaag cagcaagaaa actttatgaa tcagaaaagt ttcgtatatt
    24001 aggtaaacgg aaatcatatt atcgcaatcc gacggaagat gcgatcatta tgagcagaaa
    24061 gttaaaaacg gagacgatga aatgaatgaa gaattgattc tggcgattga atcaagttgt
    24121 gatgaaacga gtgtagcggt cgttagaaat ggaacagaga tcttatctaa catcgttgct
    24181 tctcaaataa acagtcataa acgttttggt ggcgtagtac ctgaagtagc tagccgccat
    24241 cacgtagaac aaatcacctt atgcttggaa gatgcactgg tagaagctgg tgtgtcggca
    24301 gaagatttat cggcagtcgc tgtcacttat ggaccaggac ttgtcggctc gttgctgatt
    24361 ggtatttctg cagctaaggc ttttgcttgg gcacaccaat tgccgcttat tcctgtaaac
    24421 catatggcag ggcatatcta tgcagcccgt ctggttaaac cattccagtt tccattgatg
    24481 gcacttcttg ttagcggagg acatacagaa ttagtctata tgcaagaaga tggatcatat
    24541 gaaatcattg gggagacaag agatgacgca gcaggagaag cttatgacaa agttggaaga
    24601 gtattaggtc tttcttaccc aagcggaaaa gaaatcgatc agctagctca tcagggaaaa
    24661 gataattacc attttccgcg agcgatgatc catgaagata attatgattt cagttttagc
    24721 ggattaaaaa gtgcatttat caatttggtg cataatgcac aacagcgtgg agaagatcta
    24781 gacaaaaatg atttagcagc tagctttcaa gcaagtgtga tcgatgtatt gattactaaa
    24841 acacttcgag cttgtcaaaa ttatccagtc aagcaactga ttatagctgg aggtgtagcg
    24901 gccaatcaag ggttgcgtga aggattgcag gatgctttgg caactaaact ccctgaggta
    24961 gaactagtga ttccccctct tcgactttgt ggagataatg ctgcaatgat tggagcagca
    25021 gcacatgtgg aaatgcaaaa aagaaatttt gctagctatc agttgaatgc tgatccaagc
    25081 ttggttttat ctgaataaag aggttgtgaa aaagctgccc tgcatcaagt aataagaaca
    25141 gcccaggaaa aacggcttct catgtttttg acctggctgt tcttattacc gcgtatgcaa
    25201 gcttttgaac gccgtttaat caagagttcg taagcctgtc gtttaactct gattcacaag
    25261 gaacaatttc aaaaaacagc tcctcatgtt tatgaacatt atgacttgtg accgaagagt
    25321 tgacaggtac acaccgttta atcgaaatag ggctgtgaca cgtttttgtc aaagccctat
    25381 tttttacata cttttaatca ttattgttat tttgctattt tttacagctt atttatcatt
    25441 atccgttcct ctgattgccc tcactgagta atcgtttatt gtcgaggaat atcgaataat
    25501 ctagatcgga tgaggacaag acgcttcatc tagttaatct aacagtattt tttgcaaaca
    25561 gtgaatatta cataactgaa acacacatag aaaatctttg agtcttgtcc agtgatctaa
    25621 aactgccgga tctttcagaa gttttaggga ggaaaataag cagtgaccct gatatt
//
LOCUS       DAMEEU010000041        25566 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.042, whole genome shotgun sequence.
ACCESSION   DAMEEU010000041 DAMEEU010000000
VERSION     DAMEEU010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 25566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25566
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.042"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            151..279
                     /locus_tag="PB779_001636"
                     /pseudo
     CDS             151..279
                     /locus_tag="PB779_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
     gene            393..632
                     /locus_tag="PB779_001637"
     CDS             393..632
                     /locus_tag="PB779_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739160.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            744..938
                     /locus_tag="PB779_001638"
     CDS             744..938
                     /locus_tag="PB779_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739161.1"
                     /translation="MEEKLLKTMKQKHLKRLSVMQYINDMQITGKEKACLLGSMKNFE
                     QLRRTYVKTSSNCQLLLEVS"
     gene            1024..1695
                     /locus_tag="PB779_001639"
     CDS             1024..1695
                     /locus_tag="PB779_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDE0739162.1"
                     /translation="MRKWLFGFLGVALIVFCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQQEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            1748..3724
                     /locus_tag="PB779_001640"
     CDS             1748..3724
                     /locus_tag="PB779_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDE0739163.1"
                     /translation="MAINRYVKKAGMLIGMLGIIAGCFQGYRAYAEDVTQKTPPEKVN
                     ITVHKLMYDQGTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PREDSDLTNAKVDEIVQDVEDKGSNSEYVKNATNKITSAVDENGEITFTDQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDKTGSGFLKNIHLYPKNIVSKLSFELTK
                     FGDDGADQSKQTLLKGAKFELYKGEPGKGTKLGDLVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGQEHSFQIGDAVNYQGTIHIPTDIAGGADGITVNGVKSETSPYSVFKWGDTA
                     GQGLSYVAAKANIKVTNKDGSVVLKENTDYKIQNSENGFVIDFIVNNGQVSDTVASLH
                     GQDLQMTYNMYVNDSAAVANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLVDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGEYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQTYVLISCLLLGAGALSAVVYFKKKA"
     gene            3739..4491
                     /locus_tag="PB779_001641"
     CDS             3739..4491
                     /locus_tag="PB779_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDE0739164.1"
                     /translation="MIIRKPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTILSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLESNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            4507..5262
                     /locus_tag="PB779_001642"
     CDS             4507..5262
                     /locus_tag="PB779_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739165.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGHEKQEGVNG
                     AKFSVYDVSDILQKMDVKDLTTDQIESQLKNRVKKLSSDQLKLVSNEETKTIDQQTGV
                     FEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSEAS
                     QPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            5275..5535
                     /locus_tag="PB779_001643"
     CDS             5275..5535
                     /locus_tag="PB779_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739166.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            5532..7622
                     /locus_tag="PB779_001644"
     CDS             5532..7622
                     /locus_tag="PB779_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HDE0739167.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLSNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTISAVSLLL
                     LVLATFSYAVLRYI"
     gene            7649..8113
                     /locus_tag="PB779_001645"
     CDS             7649..8113
                     /locus_tag="PB779_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739168.1"
                     /translation="MKKLIIVVTSLIAMIVILVGCSNEKNKQTNQDNGVLKSGTMWKE
                     EVGGLVYNLKIIDETTWEYSESVWHPDPVQITVKRQKDYKGLERYKIVDSAGVREFIN
                     KSDSLFIVVPYEKNGVKKIIFLGSSKDEKRTKEKLIHDGSQSNKYKLQKTSE"
     gene            8110..8352
                     /locus_tag="PB779_001646"
     CDS             8110..8352
                     /locus_tag="PB779_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HDE0739169.1"
                     /translation="MIASLFICPEGGITVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            8370..8672
                     /locus_tag="PB779_001647"
     CDS             8370..8672
                     /locus_tag="PB779_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739170.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQTAATSLKNNLMIFAAAAA
                     VASIVIGGLFFLFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGLFGQTPQGL"
     gene            8742..10805
                     /locus_tag="PB779_001648"
     CDS             8742..10805
                     /locus_tag="PB779_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739171.1"
                     /translation="MYFTIAGNTKTDKELIKKATKEVGKRTSFLPKTIKYSVIETEEQ
                     LHVLGKVLEHESRSSVKLTLTLHDTEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVNQGSEVEVNEEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDPVEA
                     NEESTWTEGDSQEYIEPLISEEVEKNEIEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWEKAKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCVA
                     KINNFTQTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMEKYEKIQQELQVQIPKWKKEYEIQQQELKEQEEKQRQKEKEREQLELKKREQD
                     LAEQQMAIEKQRLNQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPTPSVAAVQTPM
                     NNQTNLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTTSIKEE
                     AQEQARKEYEQQLEELLNRTNQSTTESSMENSKESDSSKAKEGSSDSTVQSNTSESSE
                     SNEVK"
     gene            10805..13417
                     /locus_tag="PB779_001649"
     CDS             10805..13417
                     /locus_tag="PB779_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDE0739172.1"
                     /translation="MRVRETTKRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     KKIFYSGLVYLPLEYLVTRVPEVFNRLEIVKGSLQGINLFQLQEMPQVFHFDSAGFWN
                     PFTPTTSLGTRLAISTVCVVPAVLMGLKMDMWFRPLADGQKGDNRLMTLKEIQQIYPQ
                     IPETKTTFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     KQSSMVVNDPKTELYVGSKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPDNEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSVGFPKYLDLKLHESLLNQRVVVEFYHKGK
                     KFHEERVKVGYKGFCEINFDCHLVAGDQVCLKYDHQGKEYVAWYEFSQRVLKDEEGNI
                     VYRKKRGETHLPELEKEAVLTLDEEKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGYKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSLENETAKKLLIQFYEEQAADRLQEYVEKLIKNKEISEMI
                     GKRLLLESEKVVKE"
     gene            13414..15945
                     /locus_tag="PB779_001650"
     CDS             13414..15945
                     /locus_tag="PB779_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739173.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDANPKTVTKVLQDYGNYLQYQDV
                     FSWIWNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNALFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKSFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PKQAKEMADKDKSGLSDLQKDRLRALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYR
                     RYSSKPGIILAGESSLAVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSA
                     IEDISQSFLLLAFTILELRIYTLMLSGIGDLHAAGKINGFLYVVALIVLTIALFKGSQ
                     SVTKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGF
                     GHRKDVTPDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGT
                     AEDLTEKAKDTLEEKLDGTRAKELAEAVKNPSEALEKQKEKASEVKEGLKDAYGEGQV
                     NAAVKANTTTEKENQEGIVIPSVKDHQEALHSNENSIEEKNSIEERNSEEGKNGQLPK
                     TDPEQYRYKPNSDLENEKRISDLSKVNQEDKAENEGQLPKTDPEQYRYRSVNSENEKR
                     ISDLPKRNQEVQTDEDSIVLPNDNGIEVGTEKSTKIGLPKAQNLPMKDSRLNQFKEND
                     QSFVHQSTAGTVQMKPSRLPENGNLTTVSYNLSESGETGNASVQNVVTREAAPKPIQN
                     VHTGYKPANVAFTAPTKINVTRETKNRNNALKEQLLRDIKQDIKP"
     gene            15995..16327
                     /locus_tag="PB779_001651"
     CDS             15995..16327
                     /locus_tag="PB779_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739174.1"
                     /translation="MDKYINMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKMVNNLV
                     HLPLFFALLNYGLWIAIALVIVWRPYNNPGQRQIFAIIESIFFADKNHYHALDPNRNY
                     HGTYKEDE"
     gene            16328..16921
                     /locus_tag="PB779_001652"
     CDS             16328..16921
                     /locus_tag="PB779_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739175.1"
                     /translation="MRVKGQNSVERKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLKKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            17084..19108
                     /locus_tag="PB779_001653"
     CDS             17084..19108
                     /locus_tag="PB779_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HDE0739176.1"
                     /translation="MLEAIKTAFSPQNDQKVLDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTETQVTGKDPEAYPTFKEFLDFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            19108..20307
                     /locus_tag="PB779_001654"
     CDS             19108..20307
                     /locus_tag="PB779_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDE0739177.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            20323..20967
                     /locus_tag="PB779_001655"
     CDS             20323..20967
                     /locus_tag="PB779_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739178.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPADDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            20978..21784
                     /locus_tag="PB779_001656"
     CDS             20978..21784
                     /locus_tag="PB779_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739179.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIYYVH
                     EDKVKDQVKDEDYEQHAINYKVKGYKKEQKAAQKQMESFQATIDLNEELVKKLKDQLP
                     YQVADDQENTENKINSYQQEIETSKTQMKDQEEIIQKLQEKIDRMTKEKI"
     gene            21806..22036
                     /locus_tag="PB779_001657"
     CDS             21806..22036
                     /locus_tag="PB779_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739180.1"
                     /translation="MKRTNLADKDTFAEQKVLIKAYLKVVKAKEICREVNLSNTTISE
                     LKNGRKNLDTLKFRSFEALYVAAKKYFTADNK"
     gene            22550..22858
                     /locus_tag="PB779_001658"
     CDS             22550..22858
                     /locus_tag="PB779_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739181.1"
                     /translation="MEVRIRNVDEKIVREIDRRCDELSNRTGNKWSRNDYLKLLVEND
                     FDRPLMEYKQDKFDQLLNQLIDKFSFVQSHNTKVLEEYICQNNQIIELLIEQSRGGEV
                     "
     gene            22860..23282
                     /locus_tag="PB779_001659"
     CDS             22860..23282
                     /locus_tag="PB779_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739182.1"
                     /translation="MAKVIDKHIYFYETHIDVLDEIIATHAEVKNYSEAVRFLCMNYD
                     SEVEKKVNSNQAKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKTISESVTTKSEVFDPTRFLKR"
     gene            23302..24891
                     /locus_tag="PB779_001660"
     CDS             23302..24891
                     /locus_tag="PB779_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739183.1"
                     /translation="MSKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPEE
                     EQELRLIKNALEDFYIPEGETFSESKTGKEFSETSNEAQSLMKHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKVLTHSEQKEYQRLNQAIKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQTFQRGQQKGSIIYQDVVSHDHSYLEKIGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKKNTRKPYTEIENGVSYIVPKG
                     KRRQATLDEMKTNYVHELERFSYEKNRMGMEKRNLLTRKSDLRNTLTKVVKEPVRYDR
                     HAMSLLTEVYKNLPKKRSEWHYGDENRTKLSPYTREKLDELTQYVLTKEPGYQEYIQI
                     SKALKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIERMDQ
                     MQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEEK
                     YHASKAYEEQQRRIQMEQERQ"
     gene            24903..25238
                     /locus_tag="PB779_001661"
     CDS             24903..25238
                     /locus_tag="PB779_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739184.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLINEQF
                     DPNQFLVVEYPATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            25379..>25566
                     /locus_tag="PB779_001662"
     CDS             25379..>25566
                     /locus_tag="PB779_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739185.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT         9540 a         3960 c         5258 g         6808 t
ORIGIN      
        1 gatcaaataa acaagaaccg taggaactac ggggatagct tggtaaataa gaggcacctc
       61 tgttagtaaa gtaatacgct atcaagtatg ctctcttccc aagaagctcc cacttcaagc
      121 gtaagaaacc gttaggttta gctaagtggt gagtagttca caatgacgct tacgaatgat
      181 aatggagacg aattatctgt tgaagatact tggtcatatt tgagtgatta tattgtcagc
      241 gttgaaatca ttgaatttgt agcggataaa gaagaataaa aactggagga ataaatttta
      301 cagataaagg cttagaagaa gtcacgacga ataataaaaa ggtagtatta ccttaggcat
      361 tgagtaagga attcatttag gaggaaaatt agatggcgcg accagtttta gaggcgatgg
      421 atatggatac tttgacaaaa ggaaggtatg tacagctgtt agctcgtggt tattcaccta
      481 aagatgtatt caaatccctg tctaaaggaa cagatatgga aaaagaaaga ttacgaaaag
      541 aattcgatta ttggagaacc cataatggaa tcaaggattt gaaaccagca cggccagtaa
      601 ttaaacgaaa gaaaaagata acccaagact gaagtgtaga gcgtatgtga tcataggctt
      661 ttttattttt gcaaaaaaca aggaaggtag gaaaactcat gaattatgaa gaaatcgaaa
      721 acagaaaaaa agtgtcgaaa taaatggaag aaaagttgct aaaaacgatg aaacaaaaac
      781 accttaaaag attatctgtc atgcaatata tcaatgatat gcagataaca ggaaaagaga
      841 aagcttgttt gttaggttca atgaaaaact ttgaacagtt gagacgaact tatgtgaaaa
      901 caagttctaa ttgtcaacta ttgttagaag tctcatgaca ttcattaata gaattcattt
      961 ttaaaacttt ttctatggaa atgagaaaaa gattttttgt tttgtctgaa agggggtagc
     1021 tggatgagaa aatggttatt tggtttttta ggagtcgctt taatcgtctt ttgcagtgtg
     1081 tttggctatg ttagctacca aaaacatgaa ggagaggtgt ttaagcaaaa tatagaaaaa
     1141 aagatgcccg tagatcaaat caatgcacat gcaaagagtt ataaggagga tgcaacgaac
     1201 gtcaataatg atatgtcttt ggggcaaatg ttgtccatac aacaagaagc aatcgaaatg
     1261 ggcgtcaata aacaagtatt tgcacaaatt cagattcctg cacttggttt agcattgcca
     1321 atttttaaag gggcaaatca atacactttg agtcttggag cggctactta tttttatgaa
     1381 gatgctgaaa tgggcaaagg aaactatgtc ctagcaggtc ataacatgga aatgccaggt
     1441 gttttatttt ctgatattca aaagttgtca ttaggggagg tgatggactt agttagtaac
     1501 gatggcgtct atcgttacaa ggtaacgcgt aaatttatcg tacctgagta ctttaaatta
     1561 atcgatggcg ttcctgaaga gaactctttc ttgtctttgc caaagaaagg agagaaaccc
     1621 ttattaacgt tgtttacttg tgtttatacg tcacaaggaa aagaaagata cgtggtacag
     1681 ggagaactac aataacaagg ttttaatcaa cgtgagtcgt tgaaatatga aatgaggaga
     1741 gtaaaaaatg gcaataaatc ggtatgtaaa aaaagctgga atgcttattg gaatgttagg
     1801 aatcattgca ggctgctttc agggatatcg agcatatgca gaagatgtca cgcaaaaaac
     1861 gccaccagag aaggtcaata tcacggttca taaattaatg tacgatcaag gaacgcaatt
     1921 gaatgttgat attgacggga tcaaaaacga tggttatacg cacgatcaat atcctacagg
     1981 tgtaacgaaa tacaacaagg cagattatgg tgatgttgag tttacgttag gaaatattac
     2041 ggatcaagta ttaccgagag aagattctga tctaaccaac gcgaaagtgg acgagattgt
     2101 acaagatgta gaagacaagg gatctaacag tgagtacgtc aagaatgcaa ccaacaaaat
     2161 tacttcagct gtagatgaaa atggtgagat cacttttact gatcaaccag cctatgtcaa
     2221 ttccaaaggg aatgtatatg tggtttatga aagtaaatcc gctgctggat tagtcacaca
     2281 aaaagcaaaa ccaatggttg tgattgcgcc aatgacagat aaaacaggat caggattttt
     2341 aaaaaatatt catttgtatc ctaagaacat tgtttctaag ttgagttttg aattaacgaa
     2401 atttggtgac gatggcgcag accaaagcaa acaaaccctt ttaaaagggg caaaatttga
     2461 gttatacaag ggcgaacctg gaaaaggaac aaaattgggt gatcttgtat cggatgatca
     2521 aggaaagctg actgcgactg atttgacgtt aggaaaatac tattttgtgg aagttccttc
     2581 ggaagttgta gtgggatcag atcaagaacc aacagcagat caatatttat taggcgcaga
     2641 cgctcgcaac gatgcgcaca ataaattaac ctttgaaatt acgaatgatg gcgtgacaag
     2701 tgacttaaaa gcttcatacg taaactataa agcaccagtg atcgataaaa cagtaacaaa
     2761 tggaacagga caagaacatt ctttccaaat tggtgacgca gtaaattatc aaggaacgat
     2821 tcatattcca acagacattg caggtggcgc agacggtatc acagtaaacg gtgtgaaaag
     2881 tgaaacttct ccttacagtg tatttaaatg gggagataca gcaggacagg gactttctta
     2941 tgtcgctgct aaagcaaata tcaaagtaac aaataaagat ggatctgtgg tattaaaaga
     3001 aaatacagat tataaaatcc aaaattcaga aaatggcttt gtgatcgatt ttatcgtgaa
     3061 taatggccaa gtaagtgata ctgtagcaag tttacacgga caagatcttc aaatgactta
     3121 taacatgtat gtaaatgaca gcgcagctgt tgccaatcca ttaacaaata gcgtggattt
     3181 cgtttataac aacaatccat ttaatcagga agaacaccac gaaaaaacga aagctgacgt
     3241 tgtgacttat ggtgcaaaat tcttaaaagt cgatagcgga ctatttggaa caggaatcaa
     3301 agcaacaccg cttgaaggcg cagaatttgc tgctaaaaac gcagaaggaa aatattatgg
     3361 tggattagtt gatacggata aagacggtgt caaagaagca gtatgggtag acgatgtagc
     3421 aaatgcagcg atcctaaaat cagataaaga aggtcacttt gaaatcactg gtttaactga
     3481 aggtgaatat tcactggaag aaacaaaagc gcctgaaaac tatcaaaaat taacgaaaga
     3541 gatctctttc aaagtagaca aagattcata caaagaagaa aaccgaatca cgatcaaaaa
     3601 caatcaaaaa gcttccgtac caatgaccgg tagcaacggt tttcaaacgt atgtattaat
     3661 ctcttgcttg ttgctaggag caggggcact ttctgcagtt gtttacttta agaagaaagc
     3721 ctagaaggat caaaaccaat gattatcagg aagcctaaga aaaagcgaat catgggtaaa
     3781 tggatcattg ctttctggtt actttcagct gtaggtgtct tacttttgat gcctgctgaa
     3841 gcgagcgtgg cgaaatacca acaaaatcag cagattgccg caatcgatcg aacaggaacg
     3901 gcagcagaaa cggattcttc tttggatgtt gctaagattg agttaggcga tcctgttggt
     3961 attcttacaa ttctaagtat ttctttaaaa ctaccaattt atgacggaac gtccgacaaa
     4021 attttagaaa atggtgtagg tattacggaa ggaactggtg atattacagg aggaaacggt
     4081 aaaaatcctt taatcgcagg tcatagtgga ctttataaag ataatctttt tgatgattta
     4141 ccttcagtaa aaaagggaga aaagttttat atcaaagttg atggtgagca gcacgcttat
     4201 caaatcgatc ggattgagga agtgcaaaaa gacgaactac aaagaaactt tgtcacttac
     4261 ttagaatcaa atcccaatga agatcgagta acgctaatga catgtacgcc taaggggatc
     4321 aacacacacc gttttctagt gtatgggaag cgagtaacct ttacaaaatc agaattaaaa
     4381 gatgaagaaa ataagaaaca aaaattatct tggaaatggc ttttaggaag tactgttttt
     4441 ctttcagtca tgatcattgg ttcgctattt gtttataaaa agaaaaaata aaggagggta
     4501 accaacatga gaaatagaaa atggctattt gtttgtgcag ccgctctttt ttctttcact
     4561 gcctacacac agttgacgtt tgcagacaga caagaaagca cggatagcac agaacaaaca
     4621 atccaaacgt cagatagcag cacgattcaa agcagcgatg aaaccgtcga ttcgtcaaca
     4681 gttgattctt cagaagaacc taaaattgct gaagacgatc aaatagtcaa acagaccatt
     4741 cacgttcaaa agattatttc ttcagaacaa ttagacaacc aggggcatga aaaacaagaa
     4801 ggagtaaatg gcgcgaagtt ttctgtttat gatgtatcgg acattttaca aaagatggat
     4861 gttaaggatc tcactactga ccaaattgaa tcccaattaa aaaatcgagt gaaaaaacta
     4921 tccagtgatc aattgaagct agtttctaat gaagaaacaa agacaattga tcaacaaaca
     4981 ggtgtctttg aattctcggt agaagtacag gcgaatcaga aacaagctta ttatattgtc
     5041 aatgaatcaa gtcctgaaaa catttctaat agcgaggata ttttgctatt aacacctgtt
     5101 tctgataaaa acggtgaatt cttaaaggat gtgtggatct atcctaaatc agaagcttcg
     5161 caacctaaag aagaagtaaa aaaaatcgtt tctactggcg taaagaaaaa cttctttgag
     5221 aattgttggg attttgttac tcacttgttt tctagagatt aaggaagaaa taaaatgaaa
     5281 ctgatcaaat tattattatt caatttttct tgtttaaccg cagtcttttt gtactgcggt
     5341 ttattatttt ctaaactatc tattttgcca agctaccaac tatacctaat gaggatttta
     5401 aacataccag ctgcttccat gccgctagat attatggaaa agctcattag gaatccatta
     5461 tttactacga tcaatttgat cgttattgtc ggaatttcac tagtcattta taaaaaagag
     5521 gggatgaagg gatgaatttt aaacactcgt ggacaagacg gttaaaatat gtttttccca
     5581 taatgatgat gttaggtaca ttgtttgggt taaaaacagc caatgtcttt gctgaaaaag
     5641 ttattgtcga tccgtcaaat ccaatccaga acgtaaagaa taattttatt attccaaaag
     5701 atgttcctaa tgcaaaaaca aatattactg taaacggagc gtcaaaagtt tacaaatatc
     5761 atgttgatgc caacaaaggt ggttttacag acgactacgt aggattagtg gagggaaaca
     5821 aaaatatacg ctatccttct ttccaaaaag aatacggtga aacaaacctt gttttagaag
     5881 gcgtaacaac caacaccaaa gtcaatattg actatggaaa aatcggtacg tataacggga
     5941 aaaaagtcaa tatcaagcta gttctatcta atattcactt atactcggat acgttgccgt
     6001 ggaatctact agataacaac tatacaaaaa ctcattttcg agacgatggc tataaaaata
     6061 cgaatggtgc aatgagtaaa tctaaaaaaa gaacagtact ttggatctca gacaatcttt
     6121 tctcaggaat tgtttaccat tcaacacaaa tgaatgtgca gctagtagcc acatatgagg
     6181 acggtagccc cgttcaattt tcaggagata catttatcag ttttaactct ttgaaccctg
     6241 caggaggaaa aagcacggat cttaaaggag aatatgccca ctatgacaaa atgaatacga
     6301 cagattggta tgtcagaaaa gatacggttc tttcagaatt taaatctttc tacaacaatc
     6361 tgaacgtggt aggtggccac ccaggaggaa gctctaagct gacacaagcg gataatgatt
     6421 tcaataattt gcatgataaa ttaggagatc cgaagtttgg tcaaggtact gtgtccttta
     6481 aaatatctga agcaaatccg acgtttgtga ttggttcttc taatgttcaa acctggttta
     6541 ctttatcttc tgcgacaatc tttagtgttg ttcctgatca acctgaaaaa acaggggttg
     6601 ataaaaatgg aaataacgtg aacgataaaa tgttgcaagt aggagacacg attcaatatc
     6661 gaatcaaaca gaaggtgaat cgattaggag tggatttact agcggtttac gatcgatttg
     6721 agttaatcga taatttacca aaagaagtaa attacgtcga tgcacacgtt gaaagtggta
     6781 caaataaaaa attcgatgta tctggtgaag tgacctatga caaaacaaaa caccaggtaa
     6841 aatatgcagc gaaagctgat acattaaaaa atcgaatgaa gtataacggc gaaacttacg
     6901 aattagtgat caatgtaaaa gtcaatgaat tggccaatca aaatagtgta gccaaaaatc
     6961 agggaacgtc gatcattaat aaagtagaaa aggatacaaa tatcattacc gtttatttcc
     7021 ctaaaattcc agtgaaagaa gtacaacaaa atggaaaaga tgtaaacgga cgaaatgacg
     7081 gtaagaaggg tacgccgaca gctcctttaa acgcaggatc tgaagtacaa tatctagtca
     7141 cacaaaaatg gcacacaaaa ggcgtagacg ctgcgtcaga tcactacaaa caatttagta
     7201 ttcaagatcc aattgaagct cgtttgacat ataaagaagg ttctgcgcaa gtaatagata
     7261 agagtaaagg aaaagatatt acttctgaag gcacactaac ctatgatagc aattcaagaa
     7321 cgctgaagtg ggaagcttcc gctgacttct taagtaacaa tcttttagat ggacgagaaa
     7381 ttcagctgat atttacagct aaaactccat tacaatcaga aaaaaatatt gataaccaag
     7441 ccgtagtagc agtagataat gtttctaata aaacaaatgt tgtgacaatt ggggttgatc
     7501 ctaacttgcc acaggtcatt gttcctaaaa caggttctac acatttagta acgatttcag
     7561 cggtcagctt actattactt gtgttagcaa cttttagtta tgcggttctg agatacattt
     7621 aaaataaaaa aacgaaagaa tgaataaaat gaaaaagtta ataatagtag ttacttcctt
     7681 gattgccatg attgttattt tagtcggatg tagtaatgaa aaaaataaac aaactaatca
     7741 agataatggc gtattgaaat caggaactat gtggaaagaa gaagtaggtg gtcttgttta
     7801 taatttgaaa attatagacg agactacctg ggaatactct gagagtgtat ggcatccaga
     7861 tcctgtacaa ataacagtca agaggcaaaa agactataaa ggtttagaaa gatacaaaat
     7921 agtagattca gctggtgtta gggaatttat aaacaaatct gattctttat ttattgttgt
     7981 tccctatgag aagaatggcg taaaaaaaat aatttttctt ggatctagca aggatgaaaa
     8041 gcgaacgaaa gagaaattga ttcacgatgg atcacaatcc aataaatata agttacaaaa
     8101 gactagcgag tgattgctag tctttttatt tgtcctgaag gaggaatcac agtggcaaaa
     8161 gctaaaacgc catttgaaaa agccgcgtct aaaatcttag aacgccgcgg tgtatctgaa
     8221 acacagtgga aacaagaagt ccttgaaaaa gcacaatttg acctattacg gggaaaagac
     8281 aaggacttag aaggatatat ctatcaacgt gaacgtgaaa agcttgtttt cgatgaaatt
     8341 attaaacact aaaaggagcg aacaatttta tgtttgaatc aattacaatg aattttttaa
     8401 cacaaccgaa agtagtagct gcggttgata tttttagagc attacaaact gccgcaacta
     8461 gtttaaaaaa caatctgatg atttttgctg ctgctgcggc cgttgcttcc attgttattg
     8521 ggggtctttt cttcctattt ggacgaagag gagctgaaaa tgggaagatg cacgtaggct
     8581 atgtattgat gggggtagga gttattttag cagcagcttc tattgtggtt tcgttatttg
     8641 gattgtttgg acaaacacct caaggattat aagaaagtaa aaaagtagga gtaagaagta
     8701 gtcgatactt tttactcctt ttttatgaaa ggagaatact catgtacttt acgattgcag
     8761 gcaataccaa aacagataaa gagttaataa aaaaagcaac gaaggaagta ggaaagcgta
     8821 cttctttttt accgaaaaca attaaatatt ctgtcattga aacggaagaa cagctacatg
     8881 tgttagggaa agtactggaa cacgaaagtc gatcttctgt taagttgact ctcacgttac
     8941 atgacacaga aggaaaaata gagaaagctg gtacagaata cgtttttggc ccactggatt
     9001 atcaaatttc agaaggtttc tatcctacat tgatggattt aatccgcctt gatgtgttta
     9061 aagaaacgga tgaaactatg agtgtggaag agtcttatcg aaacgaaaaa cttttacaag
     9121 ttttagaaga agagttagag agcgaccaaa gaaaagtgaa tcaagggagt gaagtcgaag
     9181 taaatgaaga agtaccatgg gaacgaccaa tatttccaaa gaaggagtca aaagaaaaag
     9241 agacagtcta tgttgacgaa caagctgata ttccgactca gaaatcgata tttgaggaag
     9301 agaacgatgt gatgggtcaa ttggaggtag atccctttga agaaacaatg gaggatgaag
     9361 agacggccga agtagaagtt gatccagttg aagcgaatga agagtcaaca tggactgaag
     9421 gggattctca ggaatatatt gaaccactta tcagtgaaga agtagaaaaa aacgaaatag
     9481 agatacaaaa ggcaactgta tttgattata ttttggatca atatccgcca gagcatgaat
     9541 ggatgaaaga aaaaaacaaa ttatttttaa atgagcttta ttcgaaatat caattacccc
     9601 aaacctatca agcattttta gagagtaaag aagaattaat ctcacagggt aaaggcacac
     9661 ttttagaaca gttagagtct gtccaatcaa caaattggca tgagcttgca caagaagatt
     9721 tattagccac ctttgaagaa cgtcaacaag aaacagatca agaaattaat gagtatgcga
     9781 cggaacagtc gtctaattgg gagaaagcaa aagaggaact aaataaagaa gaacagcgag
     9841 tgattgaaga agaagtacaa aaaattaaag agcgatacga aaagaaacgc gacaatgcgt
     9901 attccttgtg tgtagcaaag atcaataatt ttactcagac gaatcaagaa gcgttatcga
     9961 aagaaaaaga aaacttgtta aaagaacgta ttaaagaacg aaaagaagaa ttttaccgag
    10021 gtttgcgtac agataagcta aagattagca aagaattaaa tgaacaactg aataagctat
    10081 atcaaacaac gactgaagtt cttatggaaa aatacgaaaa gatccagcaa gaattacaag
    10141 tgcaaattcc aaaatggaaa aaagagtatg aaattcaaca acaagaattg aaagaacaag
    10201 aagaaaaaca acggcaaaaa gaaaaagagc gcgaacaatt agaactaaaa aaacgtgaac
    10261 aggatcttgc ggaacaacaa atggcaatag aaaaacaacg gttaaaccaa gaaaaggaaa
    10321 aagaagcagc tgctcgtaag gaacgtcaag aacaaatgga tacattgcga caagctcagt
    10381 taaattatct agcacaacct caaccaacgc cttcagtagc tgctgttcaa accccaatga
    10441 acaaccaaac aaatctaact ccttcaccac agcgttcctt taacggatgg atggtgggat
    10501 gtattgcaag tttaagcttg cttctaggtg gaggaacagt atttgctttt aatcatatca
    10561 atcaatcttc acaggctgat tctgtggcca caacgacgtc aatcaaggaa gaagcccaag
    10621 aacaagcaag aaaagagtat gaacaacaat tagaagaatt attgaatcgt accaatcagt
    10681 caacaacaga gtcaagcatg gaaaatagca aagagagtga ttctagtaag gctaaagaag
    10741 gatcaagcga ttcaactgta caatcaaaca cttccgaaag ttcagaatca aatgaggtga
    10801 aataatgcgt gttagagaaa caacgaagcg aaaagacaaa cgattcaatt tagaaaagaa
    10861 taggtatctt tctcatttct atcgctatac tccctcagga gaagagctac cagaaaaaca
    10921 tgacaaacgc atttcgaaaa agatttttta tagtggactt gtatacctcc ctttagagta
    10981 tttagtaaca agagtaccag aagttttcaa ccgattggaa attgttaagg gaagcttaca
    11041 aggaataaat ctgtttcaat tacaggaaat gccacaggtc tttcattttg attcagctgg
    11101 tttttggaat ccatttactc ctacaactag tttgggtaca cgtttagcaa tttcgacagt
    11161 ttgtgtggtt ccagctgtac ttatgggatt gaaaatggac atgtggtttc gtcctctagc
    11221 agatggacaa aaaggggata atcgattaat gaccttaaaa gaaatccaac agatttatcc
    11281 gcaaatacct gaaacaaaaa ctacttttcc aggttatgga ggtattccaa tcacacatta
    11341 caaaaaatat tggtacattc aaacagatac tgttaatacg tgtattgttg gtacctctcg
    11401 atcagggaaa ggtcagattg aagtgttagc caccattgac aatttatctc gtgcagaaaa
    11461 acaaagttca atggtcgtta atgatccaaa aacagaatta tatgttggta gtaaagatga
    11521 actagaagct agagggtatg atgtatatgc ctttaatatc accgatccac tgcaatcaat
    11581 gagtgataat ccattggcac tcatcgtgaa atactggaaa cgaggagaca tagatactgc
    11641 aacacagtta accaatactt tcacaaatac gatttattat gatgccaacg cttcagataa
    11701 caaatacttt aacgaaaacg cgcagaaagc tgtcaatgcg cttatttttg cgttgttaga
    11761 acaagctgat caaacaggag attactccaa attgacaccg aataatctcg ttgagcttct
    11821 ttctgagatt ggcggtttta attattatcc agatccagac aatgaattca aacagttgaa
    11881 tgccttagat gaatttatga atcagttgcc acctggaaac attgcaaaaa aacaatatgg
    11941 ggcaacgaaa attggatctg ataaagcgaa gggaaatatt ttatcaacgg caatcacggg
    12001 attgaatcca tttactctaa cgaaaattgc aaagatgact tctcaatcaa cgattgatta
    12061 taaatcggtt gggtttccaa aatacttaga tttgaaatta catgaaagtc ttttaaatca
    12121 acgagtcgta gtagaatttt atcataaggg aaagaaattt catgaagaac gtgtcaaagt
    12181 aggctataaa ggattttgtg aaatcaattt tgattgtcat ttagttgcag gtgatcaagt
    12241 ttgtttaaaa tacgatcatc aaggaaaaga atatgtggct tggtatgaat tttctcaaag
    12301 agtattgaaa gacgaagagg gtaatatcgt ttatcggaaa aaacgaggag aaacccattt
    12361 gccagaatta gaaaaagaag ccgttctaac attagatgag gagaaaagta acttattagt
    12421 agagtctatt cggatgcact ataccgataa accaatggct atttttatgc ttacacctga
    12481 ttatgatcca tctaaccata tcattgttag tatttttctt agtcagttat ataaagaatt
    12541 atctacgcaa tgtgttaaga ctaaaggaga taaatgtcac cgcaggattc attttatttt
    12601 agatgaattt gggaatatgc caccaatgga taatatggaa ggaatcatga cggtcacagc
    12661 tggccgaaac atgttgtggg atctgtttat tcaatcttat cagcaacttt atgcgaagta
    12721 tggagaacaa aacgcagcga ttatcaaaga aaattgtcag acacatattt atattatgtc
    12781 gacagatgat aataccatcg aagaattttc taaaaaagtg gggaataaga cggttgaaca
    12841 agagaacagt accatcaatt cattaggtat gaatactcat atcaatcgca atgttgattc
    12901 agatcgtatc ttaactcctg aaagaatttc tactttttta gaaggtgaaa cgattgtact
    12961 cgctccttta aaacgacaag atttgaaagg ttataaaata cggccgtatc ctatttttaa
    13021 tcatggggaa acgaatcttc cttatgctta tcaatatatt gaagatttca atccatcgtg
    13081 ggatatcaat gatatagaca tacattgtac acatgcggac ttggatctta aggctttaca
    13141 aattgattat gattatttcc taccagatga atatgctaga aatctctatc atggactgca
    13201 tgatcaatta gaagaaaaaa acgaagaaaa tatgttttat aaaatcgttc aatctcttga
    13261 gaatgagacg gctaaaaaat tgttaattca attttacgaa gaacaagcag cagatcgact
    13321 tcaagaatat gttgaaaagt tgatcaaaaa taaagaaatt tctgaaatga ttgggaaacg
    13381 gttgttattg gaatctgaaa aggtggtgaa agaatgatca ttggaggaat tttttctggc
    13441 atagccgact ggtggtcagg cttattcgga gaaggggatg caaaccccaa aaccgtaacg
    13501 aaagtcttac aagattatgg taattatctg cagtatcaag atgtatttag ttggatttgg
    13561 aacacttttc tgtggggatt gattaaagga ttatataatc tcaatacttt actagaaaaa
    13621 accatttatc aaagctttga tttaaaagac ttattgaacg ccgctggggt aaatgcacta
    13681 tttcaaagtt tgattagtaa ggtattggct cttttttgtg tcgtcacatt aatttattta
    13741 ggcttgaaat tttttatgag taaacaccca ccaaaagtca aaaatatctt ggttaattta
    13801 tttatggcca tgatcttgat ttttggtggg agttctttaa tcgatgaagg gttaaatatc
    13861 agtaaaagct tttacggaga cgtcactgca gcaaataaag cagataaaac gggttcacct
    13921 gcttttcaaa ttattcaaaa taatgtgatc gatgtcagta cattactagc aactgacccg
    13981 aataaagtag aatccctgcc aacagacaaa agaaatgctt taacagcgaa aaattttaaa
    14041 acagcgaata tcaatgggat tattactcct aaacaagcta aagaaatggc ggataaagat
    14101 aagagtggtt tatcagattt acaaaaggat cggttaagag cgttacaata ccgattggaa
    14161 ctagatgata atgggaaaga aattcctgtt caaattagtg acgaaggctt agcaaaatat
    14221 gtctatactt cagggtatcg tcgatacagt agtaaaccag gtattatctt agctggtgaa
    14281 tcttctttgg cggtggccta tttatttatc ctatttacga tcgttacttg cattattgag
    14341 ctggtattta aaaaattcta tttagtgatt gccgcgtcaa cggactttga gacaggccaa
    14401 cggatgaaaa gtgcgataga agatatttct caatccttct tgttattggc gtttacgatt
    14461 ttagaattac gaatctatac attaatgctt tcaggtatcg gtgatttgca tgcggcagga
    14521 aagatcaatg gattcttgta tgttgttgct ttaattgtgc taactattgc gctattcaaa
    14581 ggctctcaat cggttacgaa gattttcggt gttgatacga gtctgaaaaa cggcagtaat
    14641 tctcttctta gcatgtttgc cttaggaaat attgcgaaaa atgtgggtag cggagctaaa
    14701 aaccttgcaa gtgctggtaa gagtggttta agccatttaa atgatattcg taaaaatgga
    14761 tttggccatc gaaaagatgt tacccctgat aacggggaag aacaatcaga cgataaagct
    14821 acaactgtac ctaatagtaa gaaaacagtt tccgaaatgt tcgggaaagc gaaaaatggt
    14881 gtttctaaag ccgcagaagg tcttggttac gtcaatgaac gtgggttaaa aggaacagct
    14941 gaagatctta cagaaaaagc caaagacacc ttagaagaga aattagacgg cacgagagct
    15001 aaagaattgg ctgaagctgt gaagaatcca tccgaagcac tagaaaaaca aaaagaaaaa
    15061 gcttcagaag tcaaagaagg actaaaagat gcgtatggtg aaggacaagt taatgcagca
    15121 gtaaaagcta atacaacaac cgaaaaagaa aatcaagaag gtatagtgat tccttcagtc
    15181 aaagatcacc aagaagcgtt gcactctaat gaaaattcga ttgaagagaa aaattccata
    15241 gaagaaagaa attcagaaga aggaaaaaat ggacagttac caaaaactga tccagaacaa
    15301 tatcgctata aacctaacag tgaccttgaa aatgagaagc gaatttcaga tttatcaaaa
    15361 gtaaatcaag aagacaaagc agaaaatgag ggacagttac caaaaactga tccagaacaa
    15421 tatcggtata gatctgttaa ctccgaaaat gaaaaacgca tttcagattt accaaaacga
    15481 aatcaagaag tacaaacgga tgaggattcc atcgttctgc caaatgataa tggaatcgaa
    15541 gttggaactg aaaaatcaac gaaaattggt ttacctaagg cacaaaattt accaatgaaa
    15601 gatagtcgtt tgaatcaatt caaggagaat gatcaaagct ttgttcacca atcaactgca
    15661 ggtactgttc aaatgaaacc aagtcgtttg cctgaaaatg gaaatctgac aactgtttct
    15721 tacaatttat ctgaaagtgg tgagacaggg aatgcgtccg ttcaaaatgt tgtgacaaga
    15781 gaagctgcac caaaacctat tcaaaacgtt catacaggtt acaagccagc aaatgtggca
    15841 tttactgcac caacaaaaat aaatgtgaca agagaaacta aaaacaggaa caatgcattg
    15901 aaagaacaac tattgaggga tatcaaacag gatatcaaac cataaaaggc ctacaagtta
    15961 ggccttttat ttatatgaaa aggagaaatc aattatggat aaatatataa acatgaaaaa
    16021 ccctccaaga tttagtggag aatggaagtt tttcgctttt ttctttttag atctattaac
    16081 gcttggtggc tgcttttttt gggcgaaaat ggtcaataat cttgtccact taccactctt
    16141 ttttgcactc ttgaattatg gcttatggat tgcgatagcg ttagtgattg tttggcgacc
    16201 ctataataac ccaggtcaac gacaaatttt tgcgattatc gagtctattt tttttgcgga
    16261 caagaaccat tatcatgcgt tagatcctaa ccgaaattat catggtacgt ataaggagga
    16321 tgaataaatg cgagtcaaag gacaaaattc agttgaaagg aaatccattt tgcagtttgg
    16381 aaaaccagaa gagcgctcta tcttggactt atttccgtat aaatcctgta cagaagaggg
    16441 agtcttaatt actagagaag atcattttca acgttattat cgtgtagttt ctacagacgt
    16501 ggaaggatta aatgaacaag agaaactaga acgaatgaat cagttgacca ccgtcatgcg
    16561 tacgtatgtg ccaacaatta agttagttag tttgaccaca gagacggatc taacggaaca
    16621 aatcgtgcaa aagcggcaat tattagataa aaatcgtatg gaacagtcct taggaagaaa
    16681 tctacaacga ttaaaaaaat atgaaaagaa attagtcgaa gaaatccagg aattgaaacg
    16741 agcagaacaa gaacgtcctg acttaagctt ctttttcgtc attgaaggaa agacaatcaa
    16801 ggatttacaa accagaaacc gtcagttaat gcgatctagt ggcattttag ggttaaaacc
    16861 actctacaaa aaagaattga tcaagattct gtatcgaatg aacaatatga atgatgagta
    16921 ggaatggaga agagagaatg aaatatccgt tgatatggtt agaaaaagat gttccgaagg
    16981 aagagaccac tagaaaattt cctcacactt taagcctggg taagttggga aaagggcaat
    17041 cttttaacca agtaaagaat caaacaagaa gaggtgactg tacatgttag aagcaattaa
    17101 aacagctttt tcaccacaaa atgatcaaaa agtacttgat ccattaaagc aactaggaaa
    17161 tcgggaaata gaaattttaa aatccaaagg gtatgattta gattttttaa aacaagtgat
    17221 gccacaaggt gggttaaatt ttgatgaaga atatgtgacg tatggtaatg gttattcacg
    17281 atgtgtgaca gtttatcact acacaaaaaa tcctacgctt ttttggttgg ccaatctcat
    17341 gaacaatcct catacagtgg ccacactcga tgttagcaca gatgaaaagc aaaaagtgat
    17401 tgatcaaatc aatcgtgcct tagatgaatt aaatgatcga tcagataatg aacgaaaagc
    17461 gactgaccga aataaaagcg cagaagaata cctggaacta gcggaatatg ctcgtaaatt
    17521 gacttctaat ggggaaattt ctaagcaagt caaagtgaga gtacatgttt acggaaacac
    17581 gattcaagaa gtagatgaac gagcgcagga actgatcgaa aatctaaaag ggatggatta
    17641 tcgtgcggtg acttatctgc ataaaaccaa acgagattgg caatcgatgt ttaccatgtt
    17701 cgatgaacaa gctgaatggt tcggaaatat caaagggcaa tcactaccat cgttaaacat
    17761 tggcggaggt ttcccgttcc accaccaaac gctaaaagat ccaggaggga cacaatatgg
    17821 ggaaaccatg acaggcggcc catttgtctg gaatgcgacg tataaaaata gtgtacggtt
    17881 gtctactaat accttgcttc taggaatgat gggagctggt aaatcgaccg ttcttaaaat
    17941 gatcgcggaa gcccatttag ctgcaggaga ctttatttgg ggctttgaaa agggaaaaga
    18001 ctttattcct ttcttaaagg aatataacgg tattatggtg cgtttagacg gatctgacgg
    18061 aatgatcaat cctttagaga tatttgccac acggacgtat gatgaagcat ccagtttata
    18121 tgacgatgga tcagtcaaag atttgaagat caatgaagca gcgtcctatc aaacacactt
    18181 agacaaagtg gtctatcagg tacagttagt gagtcctcag ctaaaaggaa cgatgaaagc
    18241 agaatttaag acctacttaa atcgttttta tgaagagtat ggaacagtac cacgcggctt
    18301 tacttcctca aattcgcgtt caaatacgga gacgcaagtc acaggtaaag atccagaagc
    18361 ttatccgacg ttcaaagaat ttttagactt tttaggacaa ctggaattac caggtgcttc
    18421 ccaagagaaa aagaatcgaa aagaagaaat ggaatccatc gtagaatcct tatgtgagac
    18481 gtatggcatg atttttgatg ggcatagtac gattcgacac cttgaccaac aacagttggt
    18541 cttttttgac attgactcta ttacaggctt agatcgaggg gtacaacaat gtcaaatgta
    18601 catggctatg acgttgattt ggaatcaggc attgattcaa ggaagaagac aacgacgttt
    18661 aattaaagaa aaacaaatgg aagaacaaga cttcaaacgc ttcttggcga tgattgatga
    18721 gtgccataat gcgattaatc cagattttat tgaaacggta aattatgtca caaactttca
    18781 acgagaaatg cgtaaagtag aagcaatgac tgttttagct acacaatccc cacaagaaat
    18841 ggtgccagaa aatatgtctt ctgataactt ctcgaaactg aagaaagtct ttgaattttc
    18901 ttctacgaag atctttatgc gtatggatga atctatttta cgtcatatag aaggattagt
    18961 gggtaaatca atgacgaact cagaattaga atccattcct caacaaaatc aaggagacgc
    19021 tgtgatcaat tttggctcaa aagaaaccat tcgtgttcat tttagtccga acaaacgtca
    19081 attaaaattg tttgatggag gaaaataatg gaaaaccaaa atgaaagttt aatcaaacag
    19141 tatgttaagc gtcgtgcaaa gcggcgctta tttttgtggg tgtttggtac ttctgcaggt
    19201 ttgattacta tattgatcac tgtgtttgtg accctttttc taatacttgc ggcaggttct
    19261 attgataatt ctgattcaag tagtggtggc gaagctttta caggagaata ttcggaaggc
    19321 ttacccattt ataaagaaat caaaggaaga ggcccttttt ctgatgagat tgcgcaatat
    19381 gctgtaggtg cagcagtgaa gtataaatta ttaccaagtg tgatcctttc gcaatacggt
    19441 tatgaatcag cgtttggtac gtcggcgtcc gcaagaaatg atctcaatta ttttgggatt
    19501 acgtggtttg atgggtgtct gtttcctaaa ggaactgcgc gtggaattgg tggcattgaa
    19561 ggtggctggt acatgaagtt tcccaactca aaagctgcct tctcctatta cggctttatg
    19621 gtagccacac aatcaaattt taatgcttgt gtcggaaata aaagccctgg cgcaagctta
    19681 ttgatcttag gacgaggagg gtatgccgcc gcaggaatta ctgaagacag tgcctattat
    19741 aaaaattgta tgtctattat taatacaaat aaattgatgg agtacgatga gtttgcgatt
    19801 aaacactgga gagaaggcgg cggaactggt ggtacgatta caggaagctg gggcaatcca
    19861 ttcccaggaa gtagcttaga taaaaattcg ttcagtggag gacaactttt tgggaaaaat
    19921 ccaggaggag aattccgacc taacgggttc catgatggac tagactttgg ttcagtcgat
    19981 catccaggaa gtgagattca tgcggttcat ggcggaaaag tcgtgtacgt tggcaatcct
    20041 ggtatttcag gtttgggtgc gtgtgtgatc gtgattaatt acgatggctt gaatatggtg
    20101 tatcaagaat ttgcaaatag tacaggaaat tctcgagtga aagtaggcga tcaagtgaaa
    20161 gttggtcaag taattgggat acgagataca gcacacttgc atttaggatt tactcgaatg
    20221 gattggcgtc aagcacaagg acatgcattc attgatgatg gtacatggat cgatccgtta
    20281 ccatttttga atagcagcaa aaaatagatc aggagaaaaa atatggaaaa taaaacctta
    20341 aaaatcgtct taacagctgc aattagcgtt agtttaatcg gcaatattgc gttgttttgg
    20401 cagcttaaag aagaacaaga gacaaatacc tataaaattg aagaagtggc taaaaacgcg
    20461 tctgataagc tcaaaaaaaa ttcttctgag gcacaggcga agatcgacaa gttaaatcaa
    20521 accatcaatg agaaaaacca agaaatcgat cagctgaagc aacaagatgg cacaaaagca
    20581 aaagaggaag taactgaagc acaaagaaag acggcagaag agttcggtca attggccatt
    20641 gataaatcat taagcagaaa tgaattaacg gaaaaactaa aagatgtcgc aacccaagaa
    20701 gtgatcgaca aattaagtcc tgcagacgat gatcaccaac atgacgacta cggaagttac
    20761 tcttttacat taggtgacgt gcaaacttac gctcaaacaa gcagtgtaaa agaggaacaa
    20821 aattttgtcg tatttgttga ttatacaatc ggcaatcctc aatttaaaga tgtcaaacca
    20881 caaaaaataa aaggtggatt aactgtcact gaaaaacaag tagatggtca atggaaagtc
    20941 acagacttta gttatttcac tcgttaggag gaagaaaatg agtaagaaaa aaggagcaag
    21001 acaacgtttt aaaaaacgaa aaagttatct tagatggctg gggatcttta tgattctcgg
    21061 ctttttgatt cttgctagtc cgatttacac acataaaaag gtagacatac cagatgaagt
    21121 aagcacgaac gcatttttaa acacgaagga actgacgatg gtttcaaaag aaaaaggagc
    21181 gaaccagcaa ttagtttttg aatttgcgat cgacgatgaa gatcagagct tattaaaaga
    21241 actagctaat cttaattatc gtgtagaagt aaagacagct aaaggggatt atcaagcaat
    21301 aaaagccaaa gtgatcaagg tgtctgatga ttattttgta gtgaagttag cacatgtacc
    21361 agaagaatat atcgccatgc gtttaaccat tattcctgaa aaaattgatc caaaagtgga
    21421 tatgcaagaa ccacaagatc tgatttatta cgttcacgaa gataaggtta aagatcaagt
    21481 gaaagatgaa gattatgaac aacatgcgat caattacaaa gtgaaaggat acaaaaaaga
    21541 acaaaaagca gcacaaaaac aaatggaatc cttccaagca accattgatt tgaatgaaga
    21601 attagtgaag aagctaaaag atcaattgcc ttatcaagtc gcagatgatc aggaaaatac
    21661 tgaaaacaag attaatagct accagcaaga aattgaaaca tcgaaaacgc aaatgaaaga
    21721 tcaagaagag atcattcaaa aacttcaaga aaaaattgat cgtatgacaa aagaaaagat
    21781 ttagaaggac aggtggagtg aaaaaatgaa gcgaacaaac ttggctgaca aagatacttt
    21841 cgctgagcag aaagtattga ttaaagccta tctcaaagtt gtaaaagcta aagaaatatg
    21901 tcgagaagtg aatttatcta atacaacaat atctgagttg aagaatggtc gaaagaattt
    21961 agatacttta aaattcagat catttgaagc tctatatgta gctgctaaaa aatattttac
    22021 agctgataac aaataaaaaa caggagtatt ttatgtgaaa aaagtatata aaaaatgctt
    22081 atgaatcagc tatatcacct taaccatttg ttaatgagat gggagaaaac attaaccacg
    22141 attctaacgc aaacatcaag cacataaaac atttaacact cctcctttct ggctgaagat
    22201 ttcaaccaaa caggaagaca gcgtatcaat tatagcatac actttttctt aaattcattt
    22261 ttcatatgac aaaatatttc cttctaatcg acaaagttag aaggattttt tattgtctaa
    22321 atacacaaat aaccttaatt tataaagagc ataaggaaac gtgggaacac tttttaaaaa
    22381 aagtgttcca ataggctgtg cctattacgt ttctcaaaaa taattgtggg aacaaaatat
    22441 ttaaaaatag gatagtgaaa ggatagcaaa ggatagtaaa aggatagaag caggatagcg
    22501 aaaaggatag gctccttttc gctatccttt ttaaattgga ggaattaata tggaagtaag
    22561 aataagaaat gtagatgaga aaatcgtaag agaaattgat cgaagatgtg acgaactaag
    22621 taaccgaacg ggtaataaat ggagtcgtaa cgattattta aagctactcg ttgaaaatga
    22681 ttttgatcgt cctttgatgg aatataaaca agataaattt gatcaattat taaatcagtt
    22741 aatagataaa ttttcttttg ttcaaagtca taatacaaaa gtattagaag aatatatttg
    22801 tcagaataat caaattatcg aacttttaat tgaacaaagt agaggaggag aagtttaaca
    22861 tggccaaagt tatagacaag catatttatt tttatgaaac acatatagat gttctagatg
    22921 aaattattgc aactcatgca gaggttaaaa actatagtga agccgttcgg tttctatgta
    22981 tgaattatga ttcagaagtg gagaaaaaag taaattccaa tcaagcaaag ttgaatgcaa
    23041 tgggaaaaga aatttctatt ttaaccgaaa tggtttcaga gtttgcggat ctccatttga
    23101 aagatacagg gattttaatt ggtacaaatt caactgttta ccaagaagca aaagagcgtg
    23161 tggaaggcaa gataaaagca aatcaaacga agaaatattc tcctaagata aagaaaacaa
    23221 taagcgaatc agtgactaca aaaagtgaag tatttgatcc aacaaggttc ttaaaacgat
    23281 aaaaattaga aggagaatgt gatgagtaaa tcacctgcag tcattctcac ttgtcaattt
    23341 accttgccca ataaaaaatc tttttcaaca tacattgatt atatgacaag agaaaaagcg
    23401 ctggaagaaa aggaacgacg tacgcccgag gaagaacagg aactgcgtct aatcaagaat
    23461 gctttagagg atttttatat tcctgaagga gaaacttttt cggagagtaa gacgggtaaa
    23521 gaattcagcg aaacgtcgaa tgaagcgcaa tcgttgatga aacatggaat caattttgac
    23581 aagttagaag aacaagattt taccaaatat ctttcttata tgacacgtca ctatgcgtta
    23641 gaacaaaaga aagtactgac gcatagtgaa caaaaagaat accaacgctt gaaccaagca
    23701 ataaaaaaat atcaaacaga gccacacaaa aaagcttcag gaaatcttcc tggagttttt
    23761 tctatggctt cagacgaagt gaaaggaagt gatctgaagg agatcaagca aaccttccaa
    23821 agaggacaac aaaaaggctc aatcatttat caagatgttg tctctcatga tcattcgtat
    23881 cttgaaaaaa taggattgta cgatcccaaa acagatactt tagatgaaga aggtttaaaa
    23941 gcagctggaa gaaaaatgat ggagacattg ttcgagaaag agcaactgaa tgaaacaggc
    24001 tactggatgg caacgattca ccgaaatacc aaacatatcc atattcattt tgcagttgtt
    24061 gaaaaaaaaa atacgcgtaa accatacact gagattgaaa atggtgtgag ttatatcgta
    24121 ccgaaaggga agagaaggca agcaacatta gacgaaatga agactaatta tgtacatgag
    24181 ttagaacgtt tttcttatga aaaaaatcga atgggtatgg agaaacgaaa tttattgaca
    24241 cggaaaagtg atttgcgtaa caccttaacc aaagtagtga aagagccagt acgttatgat
    24301 cgacacgcaa tgagcttatt aactgaagta tataaaaact tacctaaaaa gcgttcggaa
    24361 tggcattacg gggatgaaaa tcgaaccaaa ctttcaccat acacaagaga gaaactcgat
    24421 gagttaaccc aatatgtgtt aacaaaagaa cctggatatc aagaatatat acagatttca
    24481 aaagcattga aagaagaagc aaaaagtctt tatggggaaa gcaagagaga atcaaaggat
    24541 gcagaaaaaa atgctctctt tgatttaaaa aagcgcacag gaaatgccat tctaacagaa
    24601 ctgaagaaac aggatagtca aataaaacct ttaatagaaa ggatggatca gatgcaatct
    24661 atttacaatg aacgatcctt tcgaacactt aaacagttgc caacgaatga atacaaatat
    24721 agttacgaag aattcatgaa gcgcaggaaa caattccaac aaagagttgt cacgcaacgg
    24781 agtttgcgtc aattaaatcg aacgattaat gcccatgaag aaaaatacca cgcaagtaaa
    24841 gcatacgaag agcaacaacg aagaattcaa atggaacaag aaagacagta ggaggaatag
    24901 caatgaaaca atatttagat caatggaaag ttatagaagg atcattaaga gaagaacgaa
    24961 tcgaacaact tcccgattgt ttagaaaaag agcatttgtt tcagataaga gaaatgttga
    25021 taaacgaaca gtttgatcca aatcaatttt tagtcgttga gtacccagct actggtgtgt
    25081 actgttgtaa tcatgtgaag ggtgaaaaat attttatcat tcaagaatat gagggcaagt
    25141 tagcgcctta ttatactact tgggaaatga atgaagaggg gatcaataac ttcccgtgta
    25201 aaagcattga agagtctatt tcactcacag aatgttagtt gttaagtgaa taaaagaagt
    25261 aaaagagtcc tgaacgtgat tgtccaggac tctttttttt cactgaattg ttttccgcca
    25321 attcattgag tggtgcgatt tccgtctaca ttatatcaaa agaaaggagg aagaagaaat
    25381 ggcttattca acgattggag ttgttgttga aaaaagcaga gacaatcttg tttttgtgac
    25441 agaaattcaa acaggcagag cttttgtagt cacagacaaa gcggcaaaag catatcaaag
    25501 tggcgatatt ttaacgttaa atctgactac gaagacgttc gtcgatgcgg cagaagatta
    25561 tccatt
//
LOCUS       DAMEEU010000042        24914 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.043, whole genome shotgun sequence.
ACCESSION   DAMEEU010000042 DAMEEU010000000
VERSION     DAMEEU010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24914)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24914)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24914
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.043"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            89..829
                     /locus_tag="PB779_001663"
     CDS             89..829
                     /locus_tag="PB779_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDE0739186.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
     gene            complement(1253..1423)
                     /locus_tag="PB779_001664"
     CDS             complement(1253..1423)
                     /locus_tag="PB779_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0739187.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(1617..1796)
                     /locus_tag="PB779_001665"
     CDS             complement(1617..1796)
                     /locus_tag="PB779_001665"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739188.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            complement(1806..2030)
                     /locus_tag="PB779_001666"
     CDS             complement(1806..2030)
                     /locus_tag="PB779_001666"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739189.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            2183..3295
                     /locus_tag="PB779_001667"
     CDS             2183..3295
                     /locus_tag="PB779_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HDE0739190.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            complement(3373..3666)
                     /locus_tag="PB779_001668"
     CDS             complement(3373..3666)
                     /locus_tag="PB779_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HDE0739191.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            3834..4148
                     /locus_tag="PB779_001669"
     CDS             3834..4148
                     /locus_tag="PB779_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HDE0739192.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            4169..6148
                     /locus_tag="PB779_001670"
     CDS             4169..6148
                     /locus_tag="PB779_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HDE0739193.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            6161..6487
                     /locus_tag="PB779_001671"
     CDS             6161..6487
                     /locus_tag="PB779_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HDE0739194.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            6503..7021
                     /locus_tag="PB779_001672"
     CDS             6503..7021
                     /locus_tag="PB779_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739195.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            7021..8373
                     /gene="celB"
                     /locus_tag="PB779_001673"
     CDS             7021..8373
                     /gene="celB"
                     /locus_tag="PB779_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDE0739196.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNNSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(8457..9962)
                     /locus_tag="PB779_001674"
     CDS             complement(8457..9962)
                     /locus_tag="PB779_001674"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HDE0739197.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(10054..10644)
                     /locus_tag="PB779_001675"
     CDS             complement(10054..10644)
                     /locus_tag="PB779_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDE0739198.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            10823..12469
                     /locus_tag="PB779_001676"
     CDS             10823..12469
                     /locus_tag="PB779_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDE0739199.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            12518..13237
                     /locus_tag="PB779_001677"
     CDS             12518..13237
                     /locus_tag="PB779_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HDE0739200.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            13716..14663
                     /locus_tag="PB779_001678"
     CDS             13716..14663
                     /locus_tag="PB779_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0739201.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            14675..15595
                     /locus_tag="PB779_001679"
     CDS             14675..15595
                     /locus_tag="PB779_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0739202.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            15636..17093
                     /locus_tag="PB779_001680"
     CDS             15636..17093
                     /locus_tag="PB779_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0739203.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            17438..18052
                     /locus_tag="PB779_001681"
     CDS             17438..18052
                     /locus_tag="PB779_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HDE0739204.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            18045..19769
                     /locus_tag="PB779_001682"
     CDS             18045..19769
                     /locus_tag="PB779_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HDE0739205.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            19766..21217
                     /locus_tag="PB779_001683"
     CDS             19766..21217
                     /locus_tag="PB779_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0739206.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(21690..23843)
                     /locus_tag="PB779_001684"
     CDS             complement(21690..23843)
                     /locus_tag="PB779_001684"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HDE0739207.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(23845..24891)
                     /locus_tag="PB779_001685"
     CDS             complement(23845..24891)
                     /locus_tag="PB779_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0739208.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
BASE COUNT         7945 a         4320 c         5018 g         7631 t
ORIGIN      
        1 ggtagaaact caagcgccaa cggggtatga attagatgcg acaccgatcg agtttgagat
       61 cgaaagaagt cagacagcgg tggtagaatt gacgaaagca aaccgactta caccaggcgg
      121 tgtcgtgttg acaaagatcg atgaccaaag cggggaagtc ctgcaaggag ctgtttttga
      181 gttacaagat gccaatggaa ccgttctgca gtcaggtcta accacaggag cagatggaaa
      241 actggcgatt gacggcttag caccaggagt gtatcagctg gtagaaaccc aagcgccaac
      301 ggggtatgaa ttggatgcga caccaatcga gtttgagatc gaaagaagtc agacagcggt
      361 ggtagaattg acgaaagaaa atcgacttac accaggcggt gtcgtgttga caaagatcga
      421 tgaccaaagc ggagaagtcc tgcaaggagc tgtttttgag ttacaagatg ccaatggaac
      481 cgttctgcag tcaggtctaa ccacaggagc agatggaaaa ctggcgatag atggcttagc
      541 accaggagca tatcagctgg tagaaactca agcgccaacg gggtatgaat tggatgcgac
      601 accagtaact ttcaagatcg aaaaagaaca agaagtggcg atctttttaa caaaagagaa
      661 tagaaaagtt gctgatagct cagatataag aggaaacaat ccaacaagca gtggaaataa
      721 gcatcttcca aaaactggag aaaccatcat tagccagttt atattgtcaa tattgggtgt
      781 gctacttgtt ttcatcagta taaaatttag aaagaaacga aatatatgag ctaaaataaa
      841 aaattgaata agcatagttt ttaaaatcaa ctagtaccca tcaattgaat ggaaactacc
      901 gattttagaa ggggtataca aacaaatatt agtatcggag tagagaaggt tgaacccaac
      961 cagtaaataa gtaaagacaa ttttgtgctg cgttgagaag tgaaaaataa acctttgtag
     1021 taatactagt taataaaaaa tatacaaaaa cactgcgaaa atcattcttg agtttcgcag
     1081 tgttttttgc ctaatgactc aagtttattg ggtaatactt tgattttctt tctacaaata
     1141 atcagcgatc agttgtaatt ttttctctag ttttaatggc tctttgtcaa taaggagaaa
     1201 aacaagtcgg gtcttttgtc tcggaaagct tcaaccaact cgtgaataaa ggttacgcct
     1261 ccttgaaagg cgtggaaaaa ccaagtaatc gatcaatcac caatttcgca tttggtagaa
     1321 catgtttggt gagctgaaag taggtggcgt tcatgtctgt aactaagaat tctatttctt
     1381 taggattagt gcagctaagg aaatagtttg ttaatcgagg aattttttgt gtaggtaaat
     1441 tttctcgatt aatttttctg tctcgccatc cgcggaaata aaactcagtt tatcctcaac
     1501 ggaaacgtga gaacgaaatt cacaaccctc aacactcaag acagaattct tttggaagac
     1561 tttggtaaat agcttctcaa ctctttcaat gtgcgaataa cggttgtcaa agatacctaa
     1621 caacttttcg aaataaaaaa taacgacact ttttcagtca gtaaagaagt gattttatgt
     1681 ctgacatgat ttgaaatcga gtgccttgga cggataaaat aactttgagc gttccaatgg
     1741 cttcgacagt ttttacaggt atagcgctgc ttttttaggc gtataaccat tggcatatga
     1801 ttatattatt caaagtggac aatggtttcc ttcttcttgt ttttcaccac cattaatttc
     1861 ctatttccat ctaccacagc agaaccacaa tttctacaga cacatggagc agggaagaga
     1921 actgcagcaa cgatcaatgt ttttttcttc tgtaaggttt cgtaagagac ctctgtaatc
     1981 atcaaatttt tgtctattga tctcagaatt tttttgatag aaccattcat aaagcatatc
     2041 gttctctcag ttgtttattt tgtggtgatt taatcataca agaaaacgat atgttttttt
     2101 ataaaaacat gaataggaaa aatagttgac aagaaaatga caacgccata tgatgttcca
     2161 tagtatttac aacctgtcat agatgactgt aaaaaataaa agtaaaaaga aaggacgaca
     2221 acaggtggat ttttatcagt ctctacaact agatccgttt attttaaaac aaaaaatacg
     2281 agaagcagct tctaaaaaag aaaagtgcat gtatatttgt tcattgtttt tacgatcatt
     2341 attcatcgta ttgtttgcca tttgttttat cattataatt acaacattat ttgaatcgaa
     2401 gcataaacca tacgctgtgg ttttattctg tatgttgatg agtattcgtt ttgttgactt
     2461 tggttataag atttcccatt cgatcatagg tttagcaatc gtcatgttct cactattagt
     2521 agcaccgtat gtccagctga tcaaatggtc agttatgggc atgttgattc attttatttt
     2581 actaagcagc atattaatgg caaccgctag tgatcccaaa atggggaatg cttctttgta
     2641 cggcttttca tatctcttta ttgtttattc gttacctaaa gattcgttga acaagaattt
     2701 ctttacacaa acaagtagct tattattttt gtttttttgt tggttttcag ttctccttta
     2761 cagaaaacat cgagaaaaga acaaagacaa aagcttgttt aaagagattt ttttgaaagg
     2821 catgtattcg caggaaaaaa tttggatgct catctatgca tttggcatta gtcttttgat
     2881 cgttgcagga gagtatgtcc cttttcagcg attgatgtgg gcagggtttg cattttcttc
     2941 tattgtatct agctatggat tgatgtcgat tggtttcaaa gaacgagcag tagaccgaat
     3001 cattggctca ttgattggat gtgttttatt tattggtatc agccaattta ttccttttaa
     3061 ctgggtcggt atattaggtg gtctagcttt aggtgtttgt tctacctata gatataaaac
     3121 agtttttaat tcttttggtg ctttggcaat cactgccagt ttattcgggg ttccaggagc
     3181 agtaacgatc cgcatttttg agaatatcct tggggtatgt ttaggaatca tgtatattgg
     3241 ggtgactgaa atacttatcc gaaaaataag agaaaaacac ggtttgaatc attagatgag
     3301 atcgaataaa aaataaggaa aaagtgaaga tacacatgga tgataaattg ctatcattcc
     3361 atgtgtatct ttttacggta aatcagtgaa acgttcgact ttcattttta atttatactt
     3421 tttacggagt tcgtttattt gagccatcat ttcggatttg tgatgctttt cgattgcttc
     3481 ttcatctttc caacggtcga tcagtaaaag agattctgga tcttctagtg gaaagtaata
     3541 gtcatatttc tcgtttcctt cttctgcacg aatcgctttg acaatgtttc tttcgaccat
     3601 ttcttctgca aattttctgg cttgtccatt tgtacttgta tacaaaatat tcactgtgat
     3661 actcactaaa tcccctcctg aaaaaattct atcactagta tatcacggtg ccagaaatta
     3721 ttattcaaga tatgatacac attttttccg caatgctacg gaaatatata ttttgaatag
     3781 aaaacgctta caagatatgc ttggtttata aaaataaaag gagtgattga tttatgaaaa
     3841 aagcattgat tatttgtgcg gcaggaatgt catcctcgat gatggcctca aagacaacgg
     3901 atttctttaa gcaaaaaaga gaagaggtac tcgtagatgc agtttcagct acagaaggcg
     3961 ataatatgat taagaatagt gattttgatt tatttctgat cagcccgcaa acgacgatgt
     4021 ttttggataa attcaaaaaa ttaggagaat ctgttggaaa gcctgttgtt agtatccctt
     4081 tccaagcgta tgtcccaatc cctacaggca tccagaagtt agcagaggtg atcgaagaga
     4141 acatatgatg gaataggagt ggatgataat gaaacagaag gaaaaattgc tgttgagata
     4201 tttgattgat cacaagaagg agtatgtcac cagtcaacgt ttagcttctg aattgttatt
     4261 atctgatcgg acaatccgta attacttgca gcggatcaaa gagttagtag aaaaaaacgg
     4321 aggtaagatc attgctaaac caggttatgg ctaccaactg catattttac aaagactgac
     4381 atttgacttg tttttgagtc ggcaagaaat agtacctgga tatgctagag aaccgcaagg
     4441 attttatgag tccgaagatc gacaaaagta tatattgaac caattgcttt tggaagatgc
     4501 cattcttttt atggatgatt tggcagaaga gctttatatc agtcgttcca gtttgacaaa
     4561 ggacatgcaa gaaatcaagg agcgattgat tccatattca ctaaaaatcg tttctaagca
     4621 tggtcaaggg acatggatcg aaggggaaga aagaaatcga cggcatttta tcatggatac
     4681 tttttttgga aaccattatg gaaattcatt gaaagaatat ttagggcaaa gccgtttttt
     4741 cccagacatc agttttgaag agctagtcat tatcattctc gatgaaacaa gagaagctaa
     4801 gttaaaagtt tcggatttta tcatacagaa tctgacttta cacttggctt tggggatcaa
     4861 acggctccga gaagggtttg aaatcaagga attaggcatc gaacaagaag tttctaagcg
     4921 agtagagtat caagtggcgc agcggatcgt tcaacgtatt gaggtaatcg caggtgtatc
     4981 gtttcccgaa gaagaaattg cttatttgac attacatctc atggctaagt cgaatcacaa
     5041 agaaaatcaa aatgatcagg aactatcaaa ggaattagcg aaagttctga aaagattgtc
     5101 tcaggaattt catttttcat tagtagagga tctccagctt ttcaatggac tactcgatca
     5161 tttgtcaccg atgatgattc gattgagccg aggtattcgc attgagaacc cattgactga
     5221 ggagataaag aaagaaaatc ccaaagtctt tgacgcagta aaaaggcatt tcagcaacat
     5281 gccggctttg aaaaactata ccatcaatga agatgaatgg gcctatttgg ctttgcatct
     5341 catggcggca ttggaaaaag aaagagctgc gcataaacta catgcattga ttatctgtgc
     5401 aacgggttac ggcagtgccc aactattaaa gaatcgcgta gtcagtgaat tcggtaaaaa
     5461 tattacagtg gtaagtgtaa aaggctatta tgagatcaat gaaacaactt taaaaggaat
     5521 cgacctgatt atttcttcta ttgatctttc gacaatgttt ttcaaaattc cagttttaca
     5581 tgtcagtatt tttttgaatg aagatgatgt tcgtaaaata cgaaaggtag ttggagaatc
     5641 tataccctat cattcctcag atagaccgat accagcattt tctctacagc aaaaaaagca
     5701 gatttacacc gaacagttgt ctgaaaaatt tttcaagact tatacgtacg aaccgaaaaa
     5761 ggaagaaatt cttcatgatt tgctgcaaaa gctgagcata aatgaagaag aaggatatat
     5821 aagagaaatg cgaaagcaga tccagcaacg tgaaaatatg ggacaaatca tattcagtga
     5881 tacagtggca gtcccacatc ccgctgttcc agttggaatc gaaacaaagg tagccgttgc
     5941 attgattcct tctgggatgc agtgggatca atatcaagaa attcattttg tttttttagt
     6001 ttcgccttct tatgtcgaaa atgaaggaat tacggtcgtg actaaagcaa tcgttaggtt
     6061 agttgaccag ctaaaagtac agcaggaaat cttagctgaa cctatttttg agaatttcag
     6121 cagtaaattt atcaaactga tcgaataagg aggaaaacag atggctgaaa aaataaacag
     6181 tgaaacacta caagtgactt cttttgatat cattttccat agcggaaatg cacggacact
     6241 gatacatgaa gcatttcgct cgatgcgtaa agagatgttt gaagaagtag aagagaagtt
     6301 gcgacaagca aatgaagaga ttcttcatgc gcatcagtca caaactcaac ttctgaaaga
     6361 atatgccagc gggacaaaaa tagaaatgga aattatcatg gtccatgcac aagatcatct
     6421 gatgacgacg atgacattat tggaagttgc acaggaaatg aattatttgt atcaaaaaaa
     6481 taaatagaaa ggaaggatca ttgtgcagga tacagtaaaa aggaaaatcg aattagaaaa
     6541 aaagcaactt agtttgaaaa acatgtattt caatcgttat ctaatcgtac gttacctgac
     6601 tgcctttttc tttttcatga acatgcaatg gatgattctg cttctatcag ctaaaagttt
     6661 aggaagtagt ttaccgatga ttctgatttt agctattttg cctgcagtag gagaacaagt
     6721 aaagctttat cgaaaacacc aaacgaacgt tccatggaca aagtggtatt ttttgttcca
     6781 gagtgtcttt aatttattag tgattccagt gttgtttacc tcaggattta cattcttgta
     6841 tccttttatg gcaaataaca atggaggaca gttatttgtt ttcattcttg ttgtaagcgg
     6901 tatttttgcc agtgcattta tacagtatcg tttaaagaaa atttcactca accaagacca
     6961 acagtatatc cgtattaaac aatatgaaaa agcgttatat ttaggaaagg agaataacta
     7021 atgtttgatt ttttgcagaa atacctgatg ggacctatgg ggaaaattgc gcaacttaaa
     7081 atcgttcggg ctgtcatggc agcggggatg gcttctattc ctttcacgat tgtaggctcg
     7141 atgtttttgg ttttaaatat tttgccatta ccgttcccat ttttagaagg attttttaat
     7201 gcaacttttt tcaaagttag tgacttgtac atgatcgtca atacaatgac gatggggatt
     7261 ttatctattt actttgccat tgtgtttgct tatgaattaa cgtcaattga acgagatgaa
     7321 caaaaattaa atgttaatcc gctcacgggg gcattactat ctgtttttgc attctttatg
     7381 tgtatccctg aattgatcat gactgatggt aaaatcagct tgattgcttc tatcaatgag
     7441 acagaaactg tagtaaatgg tattaggatg ggctcttttg tcgaacgttt aggaacttca
     7501 ggaatcttta cagctattat tatgtcgatt attgcggtcg aattgtattg tatgtgtgtc
     7561 aagagaaatt gggtcataaa aatgccagat gttgttccgc caggagtttc tcgttctttc
     7621 actgctctga tcccaacatt tgtcattgcg tttgtggtga tgatcatcaa tggattatta
     7681 gttgcactag gaacggatat cttcaaaatg attgctatcc catttgggtt tgttacgcag
     7741 ttgacgaata catggcttgg tgtcatggtg atttatttct tgatccatgc attgtggatc
     7801 gtagggatcc atggagcgaa tatcatcact tctttcttga ccccgatcgt attagctaat
     7861 atggcagcta acgcacaagg cgcaaattat ccgttggcag gagaattcaa caattcttat
     7921 gtaaccgttg gtggatcagg tgcgacttta ggattgatca tctttattgc attcctcgcg
     7981 aaatctgatc agctgaaagt gttaggaaaa gcctcacttg taccaggatt attcaatatc
     8041 aatgaaccaa tcattttcgg gatgccaatc gtctacaatc cctatttagc ggttccgttt
     8101 ttcttagctc cgatggcttc tgctacactc gcttattttg ccattcggct ggaaatcgtc
     8161 aaaccgatgc ttgcacagat gccgtggcct tcaccagtcg ggatcggagc atttgttggt
     8221 agtggtggtg attggaaagc tgctgtgtta gcagtcattt gtgcaatcat cgcattcatt
     8281 atctggttcc catttatcaa attctatgat aataaattat taaatgaaga aagagaaaag
     8341 gcagcagaat tagctagtga aaagttaaaa tgatttctaa gaaaaaagga actgtgacaa
     8401 aaaatcacag tccctttttt tcttagaaat gggaaaccac tagtatataa ataccattat
     8461 tcttcaatca accgcttcac gattgcataa tccccttcat aaggttcatc tacaccattg
     8521 attttttgat agggatccac gccttttccc gcaataacga ctgaatcttg cggagcgctt
     8581 tctgctaaag cgcgtcgaat cgcttcagga cgatccattt cataatgaac gatcaaatct
     8641 ggattagtaa ttgcttcatt gatttcttcc gcgatttttt tcggatcttc aaatgctggg
     8701 tcatctgccg tcaaaaaggc gatgtcagct gtttctgata gcacttttcc aaaatcatgt
     8761 cgacgggaga ttgctttgtt tcctgggctg cctaatacaa caattacacg gccatctgga
     8821 tgttcatttt tggcaaattt cagcaatgtt ttcaagctta gataattatg tgcatagtcc
     8881 acatagacat gcgctccatt ggattggatc aattgatcca ttcggcctgg tacacgagct
     8941 tcttttaatc cgtcttgtgc atcttgactg gaggcacctg ttagtgctgc ggcaatgatc
     9001 gcactggctg cattttcttg gttgaatcct ccagccagca aaatatcata agcagtatcg
     9061 cagatagcta agcgatcttc atgagaagat aaagtaaaac cgtgagtacc tttatctgaa
     9121 cggatcactt gataattgct ttcttccgaa cgaccataag tgatcgttgg aatctggaat
     9181 agatcggctg tttccctaag taaatcaaaa tagtcacttt catgatttaa aacaactgtt
     9241 tttgaattca agatcaattg tcgcttgcaa tagaaatagt catcaaatgt cggatgttcg
     9301 atcggactga tatggtcagg cgagatattc aagaagattc cgacatctaa agtcaagccg
     9361 tatacgcgtt gtgttttgta agcttgtgaa gaaacttcca tcactagatg agtcatacca
     9421 ttttcaactg cttctgacat catacgatat aaatctaatg actcaggcgt tgtcaaatgg
     9481 gatttgaaat atgttttgcc atctaacgtt gtattcatag tagaaagcaa tgctgttttt
     9541 ttatttgttg tgtgatccaa gattgctttt gtaaagtacg cagcagttgt tttacctttt
     9601 gttccagtga atccgatcac tttcaattta ttttgcggat agtcgtaaaa agccatagca
     9661 agaagcgcca ttgctttacg gatatccgtt acgatgattc ctactgctga attttcgtat
     9721 ggttgttctg atacataata ttgaataccc tgttcgattg ctgaatccaa atattcttct
     9781 ttgaaattca ttcctttaca gaaaaacaaa gtagaagcat cagcttttct tgaatcataa
     9841 cttaactgaa gaaattcagc tttttctggt acatcaagat gccagcctct tgttgaaaca
     9901 aattctttta atagattttc ttttaatagt aaatgacgga tgtcttctaa agagaagctc
     9961 attgattgat ccctcgcttt attcaatttc ttggtttatt atagcacact ctttttaata
    10021 tatcgtttgt ttccgctatg acaaaatcca gctttattca aattttcttg acacagggga
    10081 caagcggatg agtattttca taaacaatga actgactgta atagatagga gaacgaatag
    10141 tgtctccaac aatccaaaaa cataataatt caaaaagacg ataagactat tggtaagtaa
    10201 aagtccttgc ggcattggaa gccgaaaaaa tttgtggaaa ataatcggcg gtatcgttat
    10261 accgccattt gaggccccga ctgtgtacaa tgtgtaaacc ccaagactga acaaaagact
    10321 tcctgaaatc agtgaaaaga aatgtgagga gatcatttcc acttttggaa caatctctaa
    10381 aacaacagga aaaagcagac ttcccgctac agtcttaaaa aatactgatt ttcctaatag
    10441 gacagcggct agaagcagca tcataagatt gatgctccaa acagtaactg agcgttggat
    10501 agaaaaggcc gtttcaacta aatgtccgat ggcgcccact ccggcggaag ctatatcgtg
    10561 agggagcaag aaccaattca atccaactgt gataaagaaa agacctaaaa atataacggg
    10621 tagttttttt atttcttgtg tcattgatat ctcctataaa tgttagccat aaaaggctgt
    10681 atatttcttt actttaccaa aaaaacgaaa ccgaattcaa aaaaacaatt gttcttataa
    10741 aagttatata aaatcgattg ccagtttctg ttttaccaat taaaatgata gtaatgtttt
    10801 gtagaaagtt ggaatctgac cgatggataa tcaaagaaaa ccagcattag atcaattaac
    10861 accgcaagaa aaaatggcac gaggctctgc ttggatgacc gccagtaata tcatttcaag
    10921 attgctaggc gctgtctata tcattccctg gtatgcttgg atgggcgaaa atgctaaggc
    10981 tgccaatgga ttattcaata tgggatacaa tatatatgca ttgtttctac tgatctctac
    11041 agcaggaata cctgctgcga ttgcaaaaca aactgcacgc tataattcat tgaatgaata
    11101 tggcacttca cgacgattat ttatccgtgc attacagatg atgggcgggt taggcctgtt
    11161 gtttgctttg ttcatgtaca tcgcctctcc ttggctagct catgcttctg gtggcggaga
    11221 agaactgatt ccaacgatgc gttctttgag tatcgctgta ttggtttttc cttgtatgag
    11281 tgtgatacga gggtatttgc aaggcaatca agaaatgatg ccttatgcgc tgtcgcagat
    11341 tgtagaacag gtggcacgta ttttttatat gctattggct acattcatca tcatgaaagt
    11401 catggatggt gactatgtga cggcggtcac gcaatcaact ttcgcggcat ttatcggtat
    11461 gctagcaagt attcttgtcc ttttgtattt tttgaagaaa catcaagcgt atacatcggc
    11521 gtttattcac tacagcgaaa acaaaataaa tattgcaacg aaggaattgt tgttagatac
    11581 cgttaaagaa gcgattccgt ttattattgt gggttcaggg gtaacgatct tcaaattagt
    11641 cgatcagttc acttttatga agatcatgtc tgcatccacc gagtattcca atgcacagtt
    11701 actggatctt ttttcgattt ttagtgccaa tccagataag ttgacgatgg tagttattgc
    11761 attggcaaca tcgatcgcgt ctactgggtt accgttgatt acagaagctg ttacgttgaa
    11821 agatcgagta ggtctggcaa aattgacaag cggaaattta cagttgtttt cattttttat
    11881 gtttccggcg acatttggtg ttatgttact tgcctatccg ctaaatacat tattttatac
    11941 accggattct ctaggaagta atgtactgat ccaagcaagt tttgtaggac tcttcctagg
    12001 actatatatg ctagtttcca acatgctgca aggaatgttt gaaaacaagg cggcaattaa
    12061 ttatttggtt attgggtttc tagtgaaact ccttcttcaa tacccagcca ttcgtttatt
    12121 tgaagtatac ggccctttat tggcgacaat gatcggattt gctgtgtctt gtaccttgat
    12181 cttaaagaga atccatgaag tagcccgctt taaaccaagt tttgtctggc gcaggacatt
    12241 gctgatcttt attcttacct tgattatgct tttggcttcg tggatcacaa agatgatttt
    12301 tggtgctttt ttaaacgaag atagcaaatt ccagtctcta ttgttgattc ttgtagtagc
    12361 aggtataggg gctttagtgt atggttattt agctttgaaa atccgcttgg cagaaagact
    12421 actaggacca ggaatagcgc gtttacgaca taaattaaaa ataaaataag tgaatcagaa
    12481 gagctagatt gatgctcttt tgaaatgggg gaaacgcatg cgtttagata agtttttagc
    12541 agatatggga cttggcagcc gcaaagaagt caaaggatta atcaaaaaag gaacgatcga
    12601 agtcaatgga caagtggtga aaagcgataa agcgcaagta aatgaattcg aagatgcggt
    12661 tacttattta ggagaaatca ttacgtatca aaaagatttt tactacattt tgcataaacc
    12721 tgcaggagtc atttctgcta ctcaggataa tcatgatcaa accgtaatcg atttattgga
    12781 agaccaggat tatcgggaag atctttttcc agtcggccga ttagataaag acacagaggg
    12841 cctcttgatt ttaacgaatg acggggtgtt tgcccatcag ttactatcac ctaaaaaaca
    12901 tgtggagaaa gaatatctag ctgaggttag cggtataatg acagaagaag atatccgttt
    12961 atttgcagaa ggactgatta ttgatggcga tgagcagaca ttgccggcaa aactccaaat
    13021 tgatcaagta gatcaagaga cagaaacttc aattatccgt ctgattttgc atgaaggaaa
    13081 gtttcaccaa gttaagcgaa tggtcaaagc agtaggaaaa gaagtcttat atttaaaaag
    13141 aatccgtatg ggaaaatttt ggctgcctaa agatttgaat aaagggcaat atcgacccat
    13201 gaccaaagaa gagctagaac aagtgagaga aaaataattg aatggatagc taaaagaata
    13261 agcagagtag ttgtagcgcc atctgaaaag cagacttgtc cgtctgactt tcggatggct
    13321 tttttgtgaa atttcggctt atttccgtag aagctacttc tggaacaccg tttgttcgga
    13381 ataagggact gtgacaagac ttttgttaca gtccccattg ttccttgtga ctcagagtta
    13441 gatagtaagg acacgatctc cctaatactc aggccaaaac gctgaattca caacctctga
    13501 taaacggtgt tcaatcagct gaccctcggt attagctcaa aaaacggcaa aatatgagga
    13561 actattttcc cgtttttttc tctaatactc aggccaaaac gctgatttca caacctctcc
    13621 tatactttgt ttcattttcc ctatactttg tttatttatt ctcattattg aaagcgctat
    13681 aattacgttg cgaatgaatc gaaaggggtt tttagatgaa aaaacgaaag gggttcaatc
    13741 atttttttat gaatctatgg cgttataaag cacttgtcct gatggctgta ccgggtatgc
    13801 tttggatgat ttttttcttt tacatacctg taatggcgaa tgtcgtagca ttcaaaaatt
    13861 ttcatatttc agcagatggg ttcttggcta gcttgaggga aagtccttgg gtgggttggg
    13921 aaaatttcaa atttttattt tcttcggatc aagcatttct catcactaaa aatacaattt
    13981 tatataatgt agcatttatc cttttgaatc tgctgatctc agtcgtattt gcaatcatta
    14041 tgagcgagtt gagaaataaa cgactcgtta aagtttatca aacgatgtcc ttactacctt
    14101 attttctatc ttgggtcatt atcagttact ttgtttacgc ttttttaagt cctgacaaag
    14161 gaatattcaa tcagtggatc actggacatg gaggagaagc tgtcaattgg tataatgaac
    14221 cgaaatattg gccgtttatc ttggtgttca ttggtacatg gaaagggatt ggttataaca
    14281 gcattattta ctttgcatct gttatgggaa tcgatccgac ttattatgaa gctgctatgg
    14341 ttgatggagc tagcaaatgg cagcagatca aacatgtgac gataccacaa cttattccac
    14401 taatgacgat tttaacgatt ttagccgtag gaaacatttt ccgagctgat tttggcctgt
    14461 tttataacat tcctaggaat tccggtgcat tatatgatgt gactcaagtt ttggatacgt
    14521 atatctacaa tggcctgaca tccacaggag attttggtat gacggctgct gcaggacttt
    14581 accaatcagt tgtcggcttt gtcttgttga tgatcacaaa tacgatcgcc cgacgttttg
    14641 atagcgattc tgcattattc taaggaggaa aaaaatgaaa aaaaagaaag tggagagagt
    14701 ccaagtccgc tctttcaata agacggctaa ttttttctct aatataatga ttgcactctt
    14761 tgctatttcc tgtattttgc catttatatt tgttatcgcc atctctttta ccgatgagtc
    14821 catattgtcg actcacgggt acagtttttg gccagaaaag ttcagtatat ttggttatac
    14881 gtacttgttc gaccagatgc aggataaaat tttccaagcg cttttcgtca ctgtacttgt
    14941 tactgtttta ggtacactga tcaatagcac ggctacttct ttatatgctt atgcgatttc
    15001 acggtcaaac tttccattcc gtcgtttttt taccgttttt tgtttgatta cgatgttgtt
    15061 ctcaccaggg atggtggcca attatcttgt tatgacaaat cttcttcagt taaaagatac
    15121 gatttgggca ttgatcttgc caatggctgt cagtcccttc aatattattg tgatgcgcac
    15181 attctttaaa cgttcggtct ctgattcgat tattgaatcg gcacggatcg atggagctag
    15241 cgaactgcga atatttgttc agatcgtttt accgttagct gttccaggta ttgcgacaat
    15301 cagtttattt gccgcattgg gttactggaa tgactggttc aatgctttac tatacatcca
    15361 agatgataag ctagttccac tacagtatct tttgatgaaa atccaaagta atattcaata
    15421 tctgacacaa aattcaggag caggaagcca attgacaggc ggattagcct cagttccagg
    15481 agaatctgcc agaatggcga tcgtagtcat ctcgacgttg cctattgcga tcagctatcc
    15541 atttttccag aagcattttg tcaaaggtct aacaatcggc ggagtaaaag aataaagaaa
    15601 caaaaatata aatcataaaa ttaggaggaa gaaaaatgaa gttatggaag aaactagcct
    15661 ttacaggtgt ttcagcgttg ttgttgggaa cattagcagc atgcggaggt tctggttcta
    15721 aagaccaggc agaagctagc aattcggaca ctttgcagat gtatcaaatc ggagataaac
    15781 cagataattt cgatcaattg atggaagtag caaacaaacg aatcgaaaaa gagatcggtg
    15841 taaaagtcaa tatcaattac attggctggg gcgattacga aaagaaaatg aacgtcatca
    15901 tttcttccgg ggaaaattat gatatcgcct ttgcgaacaa ctatgtttcc aatgcccaaa
    15961 aaggagcctt tgctgatttg actgaattag cgcctaagta cgctgaaaaa gcttataatg
    16021 atttagatga agcatatatt aaaggaaatc tggtcaatgg aaaattatat gctttcccag
    16081 tcaatggaaa tgtctttgct caacaagtac ttacttttaa caaagcttta ctagataaat
    16141 acgatctttc aattgatgga atccaatctt acgctgatgc agaaaaagtc ttgaaggaat
    16201 tccatgaaaa agaaccaaac acggcagctt ttgccattgg acaaggcttc aaagtccaag
    16261 ggaactttga ttatccttta gggaatacgt taccatttgc tattgatctg gatggagatg
    16321 attcgaaaat catcaaccaa tacgataatg aaacgtatat cggactgtta cgtacaatgc
    16381 atagctggta caaacaagga ctcattccaa gtgacgctgc aacgagcaat aaggattatc
    16441 cactagaagg aaatacttgg ctaatgcgtg gagaaacaca aggaccgtat gattatggcg
    16501 atacaatttt gacaaatgca gcaaaacaag aacttgtctc aaaagcaatt actgttccac
    16561 taaaatctac agctcaagca caaatggcaa attttgtcgt atcaaatact tcaaaaaata
    16621 aagaaaaatc agtagaactt ctagggctgc ttaacagtga tccagaatta ttgaatgggc
    16681 ttgtttgggg gatcgaggga gaagcatggg aaaaagtcga tggttcagat gataaaatca
    16741 aattgctaga tggttatcag ccaaatacac atatgtctgc ttggaataca ggaaacaaca
    16801 agattctata tacacaagag tctattacgg atgacatgat tgccaaacgt gatcaatcga
    16861 ttgctgatgc agaaacttca ccgattttag gattcagctt caacactgac agtgtcaaaa
    16921 cagaattaag taatatttct aatgtcatga atcaatattt agatggattg aatacaggga
    16981 ctgttgatcc agatgaaaca ttaccgaaat tgaaagacgc tttggacaag gctggctatg
    17041 ataaggtatt gaaagaaatg caaaaacaat atgatgagtt ccgacaagaa taataatgaa
    17101 taaagacaaa ggggttgtga caaaagacgt gtcacaacct cttgttccga ataaacggtg
    17161 ttcaaaagcc agtttctcgg tattaagcta aatatatgta aaaatgtgga aagccatatt
    17221 cacaaaattt ttcttactac tcgaaactaa gcggctattt cacaaactct tggtaaacgg
    17281 tgttcaatca gctaaccctc ggtattcgct cacaaaacga caaaatatga ggaactattt
    17341 ttccgtttgt ttctctaata atcaggtcaa ggtgctgatt gcccaacctt tttttgtata
    17401 atgagaaagt ataaacttaa tgtttggagg agaagatatg ttagggaagg ttttggaaga
    17461 gttatttatc cggatctggg tcattataaa actaaccttg tatttctgga tatatacatt
    17521 tgccggcggg atcatctttg gattaggtgc ggcatggaaa acagtcaatg aactatttta
    17581 tttgtacgga ttcgagtata aagaaatcac aataaaaaga ggctggaata tatataaaag
    17641 aaatttttta agaggcaatc tgctatttag tttattttta tctggtactg ctttattgag
    17701 ttacaattta tatttatctg ttcaaatcaa agggctcatt tttttagcta ttgattttat
    17761 tttacttttt gccttgctct gcctatttgc tacttatcaa tacagtatga ttttagatag
    17821 tgaatatacg atctctgttc ctaatctgct aaagctaagt tttatttcgg ttttttccag
    17881 cttttcgtct tttctaaaaa taattattgg tagcggtata attttaggcg tgacttggca
    17941 attcaaagga ttgatcctgt ttggtgtcat tggtcttttg acggtttgga atggtacgat
    18001 gacaacacat tggcgtgaag aattagataa acagttggaa agttatgaat aagtttcgga
    18061 ttctattttc aaaaggaacc ttactaaatc gtctgttgcg gaaatacgcg gttatcatga
    18121 tcggtgtaac gatgactgct accgttattt ttagtatcca tacttgggaa caaaatcaaa
    18181 aacaggcaga aaacatgaca agtgatgccg ttcaaagcac aagcagaatg ctgaatgata
    18241 aaacaacctt gagtaggatc atcaaaaacc agcttgtagg gaattccgaa aagatcgaaa
    18301 atgtgacgac ctacttaaca aaacccatag atcagtatct gatgtatgta tacgaacagc
    18361 aaaacagtac cgatgaatta gtttctttcc caaatcaaat caaagatctc tacgcaaatt
    18421 atgaagaact aagtgcgata tatatcgtgt tgaatcaact accggagtat tatgaatctt
    18481 ctagagaaaa caaaggtggg gaaataaaaa aggggacacc aaaattacta gacgcctttt
    18541 atatcaagtt gcctatcaca caaggaggag ctgagtcagg aagtattttt attggttttc
    18601 aaaagaaaga actagatatg attttagaaa atctaacgtc attcaatgga ctctctttat
    18661 acatgatttc tggaacgaca aatcgactat acacattcca tgataataaa atagctaaag
    18721 aaacgtttga aagacaagaa atgatcatca cagagagtct gaagaaaaat tcacaattgc
    18781 cgattgacga tctggaaaaa aacaattttg ttcaacacca agaactgtct gatgattatc
    18841 gtatattagc tgtactagat aaaaaaagtg taaaaatcga aacgggaaaa aatcttgccc
    18901 cgctgatcat tggtatcatt attttagaca atatactgct tatctttctt tataaaacat
    18961 tcaaacgata ttcacagcaa gtatctatcg tcatgcaggc catggatcaa acagcagcag
    19021 ggaatttaga gacgcggatc gacataacaa acacggaata tgaactgaag gaactttcaa
    19081 tcggtatcaa cgaaatgttg gatagcatca atcagtttgt agaagacatc tacaaattag
    19141 aaatcaaaca gcaagacgca catatgcggg cgcttcaagc acagatcaat ccacactttt
    19201 tatataatac attagaatat atccgaatgt atgcaatcag cgaaggaagt gaagaattag
    19261 cagatgttgt gtatgcgttt tccgctttgc ttcgaaacaa tacgaatcaa gagaaaacga
    19321 tcactttaaa agaagaactg gacttttgcg aaaaatatgt ctatttgtat caaatgcgtt
    19381 atcctaatcg agtagcctat cattttatga tcgatcctga tttggaaaag atcgaagtac
    19441 ctaaatttgt gatccagcca ttagttgaaa attattttaa acacggtatt gattttactc
    19501 gattcgataa tgcgctaagt gtcaaagtct tgcaggaagg caaacgggta aggatcatca
    19561 tcaaagataa tggaaaaggg atgactgaaa aacggctaaa acagattgaa gaaaaactgt
    19621 ctcatcctaa agtggaactt cacggttcta tcggtctgca aaacgtgaat gaacgtttac
    19681 gtgccagctt cggcagcagt tattatatgt cgcttgagaa taatgagaca ggtggactga
    19741 ccgtttctat tacattcaag gagggatgag cgtgtatcaa gtgttattgg tagatgatga
    19801 atacatgatt ttgaatgggt taaaaaagat aattgattgg caaagtttag gctttcaaat
    19861 agtagcaaca gcagagaatg ccaaagaagg actagctgta cttgaacagc gacagattga
    19921 tttagtagta acggatgtga caatgccaga aataaatgga ctggaattta ttgaagcggc
    19981 tcaaaaagaa cgtcataatt ttgaatttat gattttatca ggataccaag aattcgatta
    20041 tttgaaagga ggtatgcaat taggcgccgt gaattatttg atgaaacccg tgaataagtt
    20101 cgaattggtt gaaagcctca agaaaatcaa aacacggtta gatcagcaaa atgaacaaaa
    20161 aaatcaacaa gaaatctatc aagaactgtt attcagtcaa tggttgaatg aagaattgga
    20221 tgaaataagt gaagaagaaa taataggaca aataagtgag aagcagcata ggatagtatt
    20281 gattcaactg gcaagaactc atgatactct tatcaataga tggttgcaag aacggcaaca
    20341 aatcttttac tatcaacgaa attacggaga ccgtgtattg atcacgttgt tgttggaggc
    20401 agatgaagtt gatggcttct gttgttttgt tcaagaaaac tttcctgatc aggaatggct
    20461 gatcagtatc ggggaagaga cagattcttt ggacaaaatc cctgaaacat tccaacaagc
    20521 gaaagacaat ctacagttgc atcaatttta tggagataaa gacgagcatg ttttttacgc
    20581 agtacaagca gaaacaaaag atcaaaccat cgatttttca agtttcagac gcgtgctgca
    20641 aaataaacaa ttggaagtcg ctcaaaaaat gatcactgat ttttttgaac agtttcagtt
    20701 agcagccatg atgccggaag atatacgata ttccagtttt ttactgttta tggagattca
    20761 acgggaattg attgatctgg aagatgagga atatttacaa ggaatcgaaa aaatccatca
    20821 ggcaaaaacg gtgcaagaac ttcagcagct acttctgtca ttcatcaaaa agcatcagag
    20881 acagaaaaag tacagtgaca atgtggaaaa agtaatcgta atcctgcacc agcattatca
    20941 agaaccactt acactcaaag aagtgtcaga aaacctgcat ttaaatgtca tgtatctagg
    21001 acagctgttc aaaaaagaaa cgaaaaaaag tttttcagct tatttgaacc atttacgtat
    21061 ggaaaaagcg aaacaactgc ttttgcacag taatcaaaac atcaatgaga tagcaagtga
    21121 gattggctac aacaacacca cgtatttctc taaattattc aagaaaatcg tcggcagatc
    21181 ccctaaagag taccgagaaa acagtggaga atcataaaag aaaaagccaa tgtaatgaaa
    21241 taacttataa aaaattgtct agaaatctaa ttttgggctg ttcttattac ttgaggcaag
    21301 gcagcttttt catgacctct cgataaacgg agttcaaaag ccagtttctc ggtattaagc
    21361 caaatttatg caaaaatgtg gaaagccatt ttcacaaaat ttttcttaat actcgaaact
    21421 aaacagcttt ttcacgacct ctccactaaa cggtgttcaa tcagctgacc ctcggtatta
    21481 gctcaaaaaa tggcaaaata tgaggaacta ttttgccatt tgtctctcta atactcaggt
    21541 cagaacgctg atttcacaac ctctcaataa acggtgttca aaagcttgca tctgcggtaa
    21601 taagaccaac caaacgaaaa atatgaggat ctatttttgc ttggctgttc ttattacttg
    21661 atgcaggaca gctttttcac aacctcttgt taattatagt ttgataagga aaaaggcaaa
    21721 tcttttgctt gatatttctt agggtgaggg atgatcccta attggtaaga gatcgtgccg
    21781 cctttcagca aatcttgatg ggtaaaatat aatttcgtat attctttgtc catccgtttg
    21841 attttatgga taaattgttg ctgcggccga ttaggcgttg cttcaatcgt caattccttt
    21901 ccatttgaca aaagcaaaac agccttgtca attaatggca taccgataac atattcaccg
    21961 gttccaggcg tgacaggata aaatcccaga ctattgaaga tataccaagc ggccatactt
    22021 ccattgtcct catctccagg gtaacccatt ggagaatcgt cgaaggtctg agtcatcaac
    22081 tgtttaagca gtggctgtgc catttcaggt tgtcctatat aactgaacaa gtaaggatag
    22141 tgaaaacttg gctggtttga aatagctaat tgtccaaatt ctatcgcggc catctcactc
    22201 atttcgtgga tctcaaaacc atatcctcct gggtcaaacg ttgggggctg attgcacagc
    22261 tcaatgagtt tttctttata tctctcactg ccaccatatt ttccgatcag tcctgaaaaa
    22321 tcgtgataaa cagcaaagct gctttgccaa gcacttcctt ctgcataatc ttgtccccaa
    22381 cgattagctg aaaatggttc tctgaacttg ccatctttat cttttgaacg cataaatcct
    22441 gactcatagt caaagatatt ttgatagttc aatgattgct gctgatattt cttcgtcatt
    22501 tcctcttctt ctagtacctt ggcaacttgg ctaatacaaa aatcgctata agcatagtct
    22561 aatgtgtgat tgactgattc gtggtagtga ttaggaacat agccatatgt caagtaatct
    22621 tctgttcctt ggcgtccata atttggatgt ttgctttgaa ccgtagcacc tttttccatt
    22681 gccgttagaa attcaggcat caagtctcgt cggatatctt ttacagcagc atctgcaatg
    22741 accgcatcga tcaatgtccc aggcataagt ccacgttcat caggagacag ccattttggc
    22801 aaatagccac tttctctata gctgttcaaa aaaccttcca gcatttcttc gtatttttct
    22861 acagcaatca aagaataaag aggataaacc gttttatacg tatcccaaaa cccattattt
    22921 gtatagagaa caccaggttt tatagatcga ctagtcgtat catagtggat tttttgccca
    22981 ctaggatcaa tttcataaaa tgtttgtgga aataaaaaca cccgatataa attatgataa
    23041 aacgtccgca attgttgttg atcatggtgt gtgagctgta tacgatcaaa ataggactgc
    23101 cattgttctt gactgtgagc aaggtaagtc tctttgcttt ggttttgttc tagttccagg
    23161 ttataagctg cttgttccga gctgataaaa gatgtcccaa atcggatagt ttgttttttt
    23221 gtctgttcaa aatacaacgg gatcgagtcg ctatttttgt tggaaacagc taactcatca
    23281 attgttaaag gatattcaaa tctcaatata aaataaaaag aaaaatcagg atcttctgaa
    23341 ccagcaaaat gtgtgatttt tccttccact gtgtaaggat ctataacaaa gagctgatgg
    23401 cgtcccggaa aggataaaag taaaccgctg tcatttttgc tgtaatcaat agataagatt
    23461 ccgccataca tgctaggtat caatgtagaa cagatgccat aacgtaattg acagatcgac
    23521 agatgagtcg ggcaaaatat actttcttct gggcggtaag aactttgagc atggaaaagg
    23581 gtgttctcct gtagttttcc attgatcggc gtaaacagca tatgactgaa atcacccatc
    23641 caaggacttg gttgatgggt aagacggtag ccttgaaaaa cgcggtcatc aggatgaaac
    23701 caccagctgc cgttttgatc cgtagtttgc ggtgcaaaat aattcatccc aaaaggaacg
    23761 ccagtataag gctggcagtt cccattagag aaatttggct gattcgctgt tgcatgtcta
    23821 gtatctattt gaccgatatt cattttattt ctcctttgtt gattgtcttt tgatgaatga
    23881 aactggaaat ttactatcgg atggtcgatc ttttgtctct aaccaagtga ccaaagcatc
    23941 tcccgcaagc ttacctaact gttcaaaatc ttgtgcgatg gttgtcagtg gcgggtcaac
    24001 aagagctgct gcttggatat catcaaatcc gataattgaa aaatcttcag ggatatgata
    24061 accatgctgt ctcaagagat tcatggtctg gatagcgaca acatcgtttt cacaaacaaa
    24121 agcagttact tcatacttag tgatataaga aagcaattca tctaatgtcg cgcttttgtc
    24181 atccagtgaa gtgtggaaag tcaaaccagc tttgtccaat gcttcaaggt aaccaaggta
    24241 acgctgtcga acggattgtg gatgagtctg cgtaccaaac aaataagcga tttttgaatg
    24301 tccctgttcg atcaaataag aggcagcaag cgcaccgcct tggaaattat cggaaagaac
    24361 ggtaggaaaa ggtaactcat agattttttt atctaatatg acgacaggga attctttcaa
    24421 tgaaagctca aaaagtaagt caagatgttg ttctgtatca agagcataat aaatcaatcc
    24481 gtcaaattca ttgattagct cttttgctgt tttattttgt agaaagtcaa gcgtcgtcat
    24541 catgacatca atctgtttat cttgcatcac agggttcaat cccttgctaa aatcaccaac
    24601 agacaaatca gcgacatatg gaagaagaaa cagaatccgt cgtgtttttg taggagaagc
    24661 aagaatctgt tccggagaag cggatttaac gaaactgcct ttcccgcgaa cgcgataaat
    24721 aagtcctaat tgctctaatt cagtcaatgc acgtttggaa gtgattctgc ttactttata
    24781 ggtacgtgaa agttcttttt cagttggtag ttggctgtct acaggtaatt caccagttaa
    24841 aatagccgtt tgcaaatcat taaatattgt ctggtacaat ggttgattca tataaacacc
    24901 tcttaatgat atat
//
LOCUS       DAMEEU010000043        24256 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.044, whole genome shotgun sequence.
ACCESSION   DAMEEU010000043 DAMEEU010000000
VERSION     DAMEEU010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.044"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            137..994
                     /locus_tag="PB779_001686"
     CDS             137..994
                     /locus_tag="PB779_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HDE0739209.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            1109..2029
                     /gene="pstC"
                     /locus_tag="PB779_001687"
     CDS             1109..2029
                     /gene="pstC"
                     /locus_tag="PB779_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HDE0739210.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            2029..2913
                     /gene="pstA"
                     /locus_tag="PB779_001688"
     CDS             2029..2913
                     /gene="pstA"
                     /locus_tag="PB779_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HDE0739211.1"
                     /translation="MNAKRSDKIATGVLYIVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            2928..3734
                     /gene="pstB"
                     /locus_tag="PB779_001689"
     CDS             2928..3734
                     /gene="pstB"
                     /locus_tag="PB779_001689"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDE0739212.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            3750..4508
                     /locus_tag="PB779_001690"
     CDS             3750..4508
                     /locus_tag="PB779_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HDE0739213.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGINLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            4521..5198
                     /gene="phoU"
                     /locus_tag="PB779_001691"
     CDS             4521..5198
                     /gene="phoU"
                     /locus_tag="PB779_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HDE0739214.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            5436..5735
                     /locus_tag="PB779_001692"
     CDS             5436..5735
                     /locus_tag="PB779_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739215.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTDQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKK"
     gene            5761..6468
                     /locus_tag="PB779_001693"
     CDS             5761..6468
                     /locus_tag="PB779_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDE0739216.1"
                     /translation="MSIGAMLLIGGKQGLFALGSLIINIVLLLLLLLIFTKTEGISLL
                     NISILFVVIGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNHWKDQGLRYE
                     ELNYLTRPYRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQV
                     GRDVIGSMTNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVL
                     SIPISVLFFLTVRRLKR"
     gene            6465..7232
                     /locus_tag="PB779_001694"
     CDS             6465..7232
                     /locus_tag="PB779_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HDE0739217.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTSVELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            7332..8900
                     /gene="liaX"
                     /locus_tag="PB779_001695"
     CDS             7332..8900
                     /gene="liaX"
                     /locus_tag="PB779_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HDE0739218.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEITQVQL
                     STTTGSIYLKDTDK"
     gene            9197..9517
                     /locus_tag="PB779_001696"
     CDS             9197..9517
                     /locus_tag="PB779_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HDE0739219.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            9517..9867
                     /locus_tag="PB779_001697"
     CDS             9517..9867
                     /locus_tag="PB779_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HDE0739220.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            10034..10972
                     /locus_tag="PB779_001698"
     CDS             10034..10972
                     /locus_tag="PB779_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HDE0739221.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            10987..11817
                     /locus_tag="PB779_001699"
     CDS             10987..11817
                     /locus_tag="PB779_001699"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDE0739222.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            11861..12886
                     /locus_tag="PB779_001700"
     CDS             11861..12886
                     /locus_tag="PB779_001700"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HDE0739223.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHYLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPAEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            12901..13839
                     /gene="galU"
                     /locus_tag="PB779_001701"
     CDS             12901..13839
                     /gene="galU"
                     /locus_tag="PB779_001701"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HDE0739224.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKKLEAEGSKIDHNPKGITEIKEEKKK"
     gene            13964..14404
                     /locus_tag="PB779_001702"
     CDS             13964..14404
                     /locus_tag="PB779_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HDE0739225.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            14407..15009
                     /locus_tag="PB779_001703"
     CDS             14407..15009
                     /locus_tag="PB779_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HDE0739226.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIMIDVKDAAGKAGDTVNEG
                     MSEAKPVADDTKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
     gene            complement(15077..16183)
                     /locus_tag="PB779_001704"
     CDS             complement(15077..16183)
                     /locus_tag="PB779_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDE0739227.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRARYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLASIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            16393..17394
                     /gene="ccpA"
                     /locus_tag="PB779_001705"
     CDS             16393..17394
                     /gene="ccpA"
                     /locus_tag="PB779_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HDE0739228.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLVDRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEEFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(17730..20075)
                     /locus_tag="PB779_001706"
     CDS             complement(17730..20075)
                     /locus_tag="PB779_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDE0739229.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            20354..21256
                     /locus_tag="PB779_001707"
     CDS             20354..21256
                     /locus_tag="PB779_001707"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HDE0739230.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            21469..23244
                     /locus_tag="PB779_001708"
     CDS             21469..23244
                     /locus_tag="PB779_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HDE0739231.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYSSSKKMLPWFLGLAVSFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEAKKLKERPFLLSKQEWLKLSLFLLPLVGFSIVYQWIEYKNETTYSIAAIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALDASPTFHAVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYQKGT
                     IKKKKEFYLMGSGDGKTMNDLPIVFAFLKSGYAYAWRYKDFHQGGNYSFGTQEQVEQA
                     QELLNLPLMDNWIDSSDPRTPDFQLTKTAKVANVMIKIYQVLAIPVLIASIAGILLMI
                     LGTAFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            23501..>24256
                     /locus_tag="PB779_001709"
     CDS             23501..>24256
                     /locus_tag="PB779_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0739232.1"
                     /translation="MPYILALDVSMGHSYSVLYKDDTCLFEDEIEHTQRGFHALLEEI
                     QHLPERPLIVFEATGIYSRPVEKFFQDHHFSYCLLNPLEAKKQMEENTLCSWKTDKSD
                     AHRLAQTHLKNQRQPKEVQSNFYLEMRDLARFYQEIEKKITRLRMDLHNCLQLTFPEL
                     EQFFLNRLTPYALILIRLFPHPDFVLASTRTKIKNKLINETRKKISANRAEQKADQII
                     HYAQCAYPAVEKDSIHCQKTIYYAELLQDLLEQK"
BASE COUNT         7748 a         4334 c         5089 g         7085 t
ORIGIN      
        1 agcatagaaa cttttaatga gatagttttt tttacaatta tgagaattta ttttgttatt
       61 taatgatttt gattcgtttt catcaagtaa tgaaaatgat aaaataaaca tactttagga
      121 ttaaaggaga tttctaatga aaaaacttaa attattctta ccaataatag gattagccat
      181 tcttttatca ggctgttcaa agtggattga tcgaggagaa tccattacgg ctgttggctc
      241 ttctgcttta cagcctttag tagaaacagt tgctgaaact taccagacag aaaatcctgg
      301 aaaattcatc aatgtacaag ggggcggaag cggaactggt ttgtctcaag tacagtcagg
      361 agcagtcgac atcggaaact ctgatttgtt tgcggaagaa aaatcgggga tcgatgcctc
      421 agcattagtc gatcatcgag tagcagttgt tgggatcact cctattgtga acaaggatat
      481 tggcgtaaaa gacatcagta tggaaaacct gaaaaaacta tttacaggcg agatcaaaaa
      541 ctggagtgaa gtcggtggaa aagatcagcc agtagttata ttgaaccgcg cttcaggaag
      601 cggaacccgt agcacgtttg aaaaatgggt attggacgga gaaacagctg ttcaggcaca
      661 agaacaagat tcaagcggaa tggtgcgcca gatcgttgcc gacacacccg gtgcaatcag
      721 ctatgttgct ttttcttatg tttccgatga tgtagatacg ttgaatgtta acggtgtaga
      781 accgacagat gaaaatgtga caacgaacaa atggacgatt tgggcatatg agcatatgta
      841 cacaagagat catccaaaaa aactgacaaa agaattttta gactatatct tatctgatga
      901 agtacaagat aacatcgttg gagaactagg ttatatccct gtttctcata tgaaagtcga
      961 acgtgattgg caaggaaata tcgttaaaga gtaatcttta cacaaaattt acaaacttag
     1021 ctaaactttt acatgttatt aaaaccaaat tgatgttcaa tttgtacact gagtgagtat
     1081 gttaaacctg attaaggggg agtcatctgt ggaagatgtg aaaaaagtat tattaacaaa
     1141 atcaaaacgt tcaaaaatgg aacagcgtgg aaaattcatc agttttttat gtatcgcgct
     1201 gatcgtgttg gttgtattat ctatttttta ttttgtagct agtaaaggat tggccacctt
     1261 ttttactgat aagatcaatg tatttgattt tctgtttggt acagattgga atccaagcca
     1321 aatcggagca aatgggaaac caatggtagg ggcattgcct atgatcacag gttcgtttat
     1381 tgtgaccttt ttatctgcta tcgttgccac gccatttgcc attggtgcag cagtattcat
     1441 gacggagatc tctcctaaaa acggaacgaa gatcttacag ccggtcatcg agctgcttgt
     1501 aggtattcct tctgtcgttt atggttttat cggtttatca gttatcgtgc cttttgtcag
     1561 aagtattttt ggcgggacag ggtttggtat cttagctggt acatttgtgt tgttcgttat
     1621 gatcttgccg actgtcacaa cgatgactgt tgatgcatta aaggcagtgc cacggcacta
     1681 tcgggaagct tcattagcgc ttggtgccac aagatggcaa acaatctaca aagtcgtgct
     1741 acgagcagcc gtgcccggga ttttaacagc agtcgttttt ggtatggctc gtgcgtttgg
     1801 tgaagcctta gctatccaaa tggtcatcgg taatgcagca ttgatgccaa caggacttac
     1861 tactcctgct tctacattga cgtccatctt aacaatggga atcggaaata caatcatggg
     1921 aacagttgaa aataatgtgt tatggtcatt agcgctgatc ttgctattga tgtcattatt
     1981 ctttaatatc gtgatccgta tgattgggaa gaaaggagag ctgaaataat gaacgcaaaa
     2041 cgctcagata aaattgctac aggtgtttta tatatagttt cggggatcat cgtattgatt
     2101 ttagcagctt tactacttta tatcttagtt cggggaatac cgcatatttc atggtccttc
     2161 ttgaccgaac cttccaaagc ctaccaagaa ggcggtggaa tcgggatcca gctatttaac
     2221 tcgatttatt tgcttttgat cacgatgatc atcagttttc ctatttcttt aggtgcgggt
     2281 atctatcttt cagaatatgc tggaaaaaac tggctaacag atgtgattcg cacgtcgatt
     2341 gaaatcttga gctcgttgcc ttctgtcgtt gtcggtttat tcggtttctt ggttttcgtt
     2401 attcaattcc agtatggttt ctcgattatt tctggtgcat tggctttgac tgtattcaac
     2461 ttgcctcttt tgactagaac agttgaggag tctttacaag cggtccatta cacacaacga
     2521 gaagcaggat tggccttagg tttgtcacgc tgggaaacag tgataaaagt ggtggttcca
     2581 gaagcgacac cagggatttt gactggtgtg atcctaagtt ctggaagaat ttttggtgaa
     2641 gcagctgcat tgatctatac ggctggacaa agtgcacctg cgttagattt tacgaactgg
     2701 aatccattaa gtgtttcaag cccgatcagc attttccgtc aagctgaaac attagctgtc
     2761 catatttgga agatcaatac agaaggcacg atgcctgatg gtgtttctgt ttcggctggc
     2821 gcttctgccg tgttgatcat tgctgtttta ctgttcaact tcggcgctcg tgcgattggc
     2881 aaacgattat accgaaaaat gacttcagcc taaggagaag aagcaaaatg aaaaaatata
     2941 actggaatga aacaaatgtc atcaccatgc caaaagagaa agaagtagca ctatatacgg
     3001 atgatctaca tgtctggtat ggcgacaatg aagcaatcaa aggagtggat ctggaatttg
     3061 aaaaaaataa gatcactgca ctgattggtc cttccggctg cggaaaatct acgtatcttc
     3121 gttcgttgaa tcgaatgaat gatgggatcg ctaatacgaa aatcactggg aaaatcatgt
     3181 atcaaggcgt agatattaat gcgcctcaag tggatgttta tgagatgcgc aaacggattg
     3241 gcatggtttt tcaacgtcct aatccgttca gcaagtcgat ttatgacaat attacatttg
     3301 ctttgaaaca gcacggcgaa aaaaacaaaa agaaattaga tgaaatcgtt gaaacaagct
     3361 tgaaacaagc tgccttgtgg gaccaagtaa aagacagctt ggacaaaagt gccttggctt
     3421 tatctggcgg gcaacagcaa cgtttatgta ttgctcgtgc gatcgcgatg aaacctgata
     3481 tcttgctgct agacgagccg gcaagtgctt tggaccctat ttcgacagga acggttgaag
     3541 aaacacttgt aaacttgaaa gaagactata cgatcatcat cgtgacgcat aacatgcaac
     3601 aagcagctcg tatcagcgac tatactgcct ttttctatct aggaaaagta atggaatatg
     3661 acaaaactaa caagatattt accagaccaa aaattcaggc aaccgaagat tatgtgtccg
     3721 gtcattttgg ttaagacgga ggcctcaaca tgacaaaaga aattatttca tctaaagatc
     3781 ttcatctgta ttatggaaag aaagaagcac taaaagggat caatctaagt ttcaatcaag
     3841 gggaaatcac tgcgatgatc ggtccttctg gttgcgggaa atccacttat ctgcgttctt
     3901 tgaaccggat gaatgacctg attccgaatg taacgatcac cggaagtgtt ttatataaag
     3961 acaaagacat ctatggtcca aaaacagatg ttgttgaact aagaaaagaa atcggcatgg
     4021 tattccagca gccaaaccca tttccttttt ctatctatga aaatgtcatc tatggattga
     4081 aattaaaagg ggaaaaagat aaaaaagtcc ttgatcaagt agttgaagaa agcctgaagg
     4141 cagcgtctgt ttgggatgat gtgaaagaca aattgcataa aagtgcttta tctttatccg
     4201 gtgggcagca gcagcgtgta tgtatcgcac gtgttttggc agttaatccg gaaatcatct
     4261 tattggatga accaacaagt gcgcttgatc ctgtttctac tgggaaaatc gaaagtatgc
     4321 tgttagaatt aagagagcgg tatacgatga tcatcgtgac ccataatatg tctcaagctt
     4381 cacgtatttc agataagacg gcattctttt tagatggtca cttgatcgaa tacaacgata
     4441 cgaagaagat attcatgaat ccagaaaaac aagagacaga agattatatt tcaggtcgat
     4501 ttggataagg aggaaacgga atgctacgta cacaatttga agaagaattg ctgaatctcc
     4561 ataatcagtt ctacgaaatg gggatgatgg tgagcagcgc cgtgcacaag tcagttcgtg
     4621 catacatcaa acacgataaa atcttagccc aagaagttat cgaaaacgat ataaatatca
     4681 ataacatgga aacacgcttg gagaagaaaa gttttgaaat gatcgcattg caacagccag
     4741 ttacaactga tttgcgtatg atcattacgg tcatgaaagc tagctcggat ttagaacgta
     4801 tggccgatca tgcggtgtct gttgctaaat ccacgattcg cgtaaaaggg cagacgagaa
     4861 taccggaaat cgaaaaagag atctccgata tgtccgatta tgtgaaaaaa atggtggaca
     4921 acgtcctagt tgcttatgtc aaaacagacg aaaaagacgc acgtacgatc gccaatatgg
     4981 atcaaagagt caatgactat ttcaatcgaa tctataatgc aacaatcaaa aatatgcagg
     5041 aaaatcctga gacagtcatc agtggaacag actacttgaa tgttgccagt tatctagaac
     5101 ggatcggaga ctatgtgaca aacatctgtg aatggatcgt ctacttggct acagggaaaa
     5161 tcactgagtt aaatacgaac cacaatgaga ttttctaaac tgaagctgtg attatgccgt
     5221 ttgtttagga aaagaggttg tgaaatcagc ggttgtgaaa aagctgttct gcatcaagta
     5281 ataagaacag tcaaacaaaa aatagctcct catatttttc gtttggctgg acttattacc
     5341 gcagatgcaa gcttttgaac accgtttatt cgggaaaggg tttgtgacaa aacatgtcac
     5401 aaaccctttt catcatttca tagaaaggat aaagaatgca aaaaaaaatt agcatcatca
     5461 ctatattttt tatttgtgtg cttacttcat gggttattca gcatcaagct gctttatatg
     5521 aagtacctgt catcgagatc gaaaaagtac gaataaaaga ggatcatcaa ttgattacag
     5581 gaagactgat gaacacggat caaaaaggag aatcgattta tttatcggtt ccttatcaaa
     5641 aaaatcaaat agaaacagca aatataaaag cgagacaaat gtatctagtc caaatgcatg
     5701 gagatgaatg gcagctagta gcaaaaaaaa aatgatggct ggcttttctt cttcacaagt
     5761 atctccattg gcgccatgtt gcttattggc ggaaaacagg gtctatttgc tttaggaagt
     5821 ctcatcatca atatcgtttt acttttactt ttgttgctca tctttactaa aacagaaggg
     5881 atttctctat taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg
     5941 gctttagatg gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt
     6001 tttttagcat tttttatttg tcttttgaca atgaatcatt ggaaagacca aggactgcgc
     6061 tatgaggaac tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg
     6121 attggaacag ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa
     6181 ttgactaagc gacaaccaga aataacagcg aaacagttat ggctttcagg aaggcaagtg
     6241 ggtcgagatg tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca
     6301 gttccatcgc ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag
     6361 catttatcat tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc
     6421 cctatctcgg tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta
     6481 tacttgttgg gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata
     6541 ttcttttagg cttattcatc aatttaggga tctttttcct gttgttattc ggttatcatc
     6601 agaagtggcc gatactggca ttgtcggtca taggattttt attgattgct gtggttatct
     6661 tattttttat caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct
     6721 ttttattttg tttcctacta ttgcttccta tcactgattt tttagcgatc caaggtttta
     6781 catcggtaga actagaagaa ttatctggct tagataagac tttagcgatt gattttagat
     6841 tacttacgag atcgttgctt ctgattagtc ttagtggtgc tgttttagat gctagtgtag
     6901 caatttctag tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat
     6961 tgcgccattc tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc
     7021 tttttgcatt catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc
     7081 cttttcagca agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta
     7141 ccacattgtc tgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta
     7201 caaaaaagaa agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt
     7261 ttactgaatc agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg
     7321 aggcaatttc catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt
     7381 cgactgaaga aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa
     7441 taaaaaaaga agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat
     7501 tgatcgataa acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa
     7561 gagaaaggca agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga
     7621 ataaaacttc ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac
     7681 gcaatgagaa acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga
     7741 cagaagaaga attagcacag cgtcagacgt tagaagcaga aatcaaagaa ttagaagcta
     7801 gtggcgatac actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta
     7861 agaatcaatg gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt
     7921 ggaaagatca agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat
     7981 cacagttagg caaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca
     8041 acatggaatg gaaagatgtc agcttacgtg tccctgggat tgcgacaacg aaatttgagc
     8101 atgaatttta ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa
     8161 acgtgacgtt aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt
     8221 acggaaaaat gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta
     8281 atgaagatca tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct
     8341 acttacctaa acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga
     8401 ttgaaacatt ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg
     8461 accaattaac tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa
     8521 acgggaacat cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga
     8581 cagcagaaaa cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag
     8641 ataatttgaa aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag
     8701 atggcatcgg tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt
     8761 ccaattacga agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc
     8821 gtgtttcaga tggtgaaatc acgcaagtgc aactttcaac gacaacagga agtatctatt
     8881 taaaagatac agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa
     8941 gcgattttgt aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta
     9001 tctcttgaac accgtttacc aagagattat gaacctgcca attatcgccg agtcacaagg
     9061 aataatttca gaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt
     9121 tgcagaaaga caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt
     9181 agaacagagg tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt
     9241 gacagggact ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt
     9301 gctttatgta ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt
     9361 agctttgatt atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata
     9421 ttatgaaaaa aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc
     9481 ggaaaaaatc gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta
     9541 gttaatacgt taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc
     9601 agtatttgga cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa
     9661 ccgattttga cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt
     9721 gttatcaatg cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt
     9781 ttttcttcat tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt
     9841 gtcagtgaac ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt
     9901 tttatttaga atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt
     9961 ttaattggta gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa
    10021 tgaggtagca tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt
    10081 ggaaatcgtg acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc
    10141 acgcccagga ctagagttga ctggttattt taattattat tcccataatc gtttacagct
    10201 atttggcagt aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat
    10261 catgagaaga ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccggc
    10321 tccagaagaa atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat
    10381 ctcaacttct cgtttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg
    10441 aacaagtgtc cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga
    10501 cagtgggata ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggtc atcgattgat
    10561 cgcagacgat cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc
    10621 taaaatcctg gaacatctaa ttgaaatccg aggaatcggg atcattgatg taatgaatct
    10681 ttttggtgcg agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc
    10741 atgggcaaaa gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc
    10801 ggaagtgggc attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat
    10861 cattgaagta gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac
    10921 atttgaagaa agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt
    10981 gacaatatgt tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac
    11041 tggtatgcat tgatcatcgt atcaggtatc attatcgcca tgtggcttag cagcagagag
    11101 gctgttcggg taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct
    11161 atctccatta ttggtgctcg cttatattat gttttatttg atcttcccca gtatatagct
    11221 gatccaatcc aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt
    11281 gcaggcgcga tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt
    11341 ttagatatcg ctgcaccaag tgtattatta gcacaggcaa tcggtcgttg gggaaatttc
    11401 atgaaccacg aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta
    11461 ccgcaattca tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt
    11521 tatgaatcac tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca
    11581 caccttttga aaaaaggcga agtcctttta tgttatctaa tgtggtatag tttcgggcgt
    11641 ttctttattg aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct
    11701 caattattat ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa
    11761 aaaggaaatt taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt
    11821 ttagagcgtt aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt
    11881 tttaggacca ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga
    11941 cgttcggatt tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa
    12001 tcaacgttat ttaccagatc attatctacc cgattccatc caagcattca ccaatatgga
    12061 agatgcagta aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc
    12121 tgttgcaaaa gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa
    12181 aggattagaa cagggaacac ataaaaggat ctctgacatc ttgttagagg aaatcccagc
    12241 agaaaaaaga aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcgaa
    12301 acatgacatc actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca
    12361 agagctgttc atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga
    12421 gatgggggca gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg
    12481 gtttggcgat aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt
    12541 aggtgtagca atgggtgcca acccgctgac ctttatcgga ttaagcggag taggcgatct
    12601 agtcgttact tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca
    12661 agggcagccc ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac
    12721 tactcaagca gcgatggaac tagcccaaat aatggaaatc gaaatgccca tcactcaaac
    12781 aatctatgaa gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt
    12841 acgtgatggg aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat
    12901 atgaaagtca aaaaagcagt tattccagcg gcaggattag gaacaagatt tttaccagca
    12961 acaaaagcta tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc
    13021 gttgaagaag cgttgaaatc aggaatcgaa gacatcttga tcgttacagg aaaagctaaa
    13081 cgaccaatcg aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa
    13141 ggaaagaccg aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc
    13201 cgtcaatctc atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga
    13261 aatgaaccgt ttgtcgttat gctaggcgat gatatcatgg aagatgaagt accattgaca
    13321 cagcaattaa tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt
    13381 cctcatgatg aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg
    13441 ttatacaatg tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta
    13501 gctattattg gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa
    13561 ccaggagccg gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa
    13621 cgcgtatttg cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt
    13681 atgaaaacaa gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag
    13741 tatatcctgt ctttaggtaa aaaattagaa gcagaaggaa gcaagatcga tcataatcca
    13801 aaaggaataa cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc
    13861 agctgctaat tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa
    13921 atgctatcct tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat
    13981 tgcaggattg atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt
    14041 gttgcaagtt tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac
    14101 gatcgaaatc gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttgctggt
    14161 caaaagtaat gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt
    14221 cacagcagtt gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat
    14281 cgcgacgaaa gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt
    14341 cggtgggaca gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa
    14401 ataaaaatgg ctaaaaaagg tggattttta ttaggtgcag tagtcggagg aacagccgca
    14461 gcaatcgccg cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct
    14521 gcccaagcgg atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa
    14581 tcgactgagt taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt
    14641 gatctagcag gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa
    14701 tctgacgata tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa
    14761 aaaacggcag aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact
    14821 tcagaagata tcatgattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat
    14881 gaaggaatgt cagaagcaaa accagttgca gatgacacaa aagaaatgat gaaaatggca
    14941 aaagaagatg cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca
    15001 aatcactaaa atcactaaaa tcacaaattt atagaataaa aaggtgggag cggactagct
    15061 ctcacctttt ttactcttat ttttctaaaa ctagtaattc ttttggtgta gtcgtgaatg
    15121 gcacacagcc atcgcttgtc acatatacac agtcttcgat acgtacccct actttttcag
    15181 gaatatagat tcctggttca agagagaagc acatcccttc ttcgattact aagtcatttc
    15241 cttctacaag ggaagggaat tcgtggacgg ttgttccgat cccgtgacct aaacggtgat
    15301 tgaaatattc gccgtagcca tagctgttga tcacgtttcg tgcgatttga tcaagttcac
    15361 ctgctgtcac acctggacgg acggcttctt gtgcggcaag ctgtgcttca agagtgatgt
    15421 tgtatatttt ttcttggaag tcggttggtt tttgataagc aattgtacga gtagcatcac
    15481 tgcaatagcc attccaaaca acgccaagat cgaataacac aagttcattc ggtgaaatct
    15541 tcgtgtttcc tggtgtacca tgagggcttg cagcatttgc tcctgcaagg actaatgtgt
    15601 cgaaagacat ttgtgaaaca ccttgttttt tcaattggta ttcgatttct gcaatgatcg
    15661 cttgttcagt cacgccttct ttcactgctt taaagccaat ctcaaatgca acatcggccc
    15721 atttaccagc ttcgatcagt ttgtcttttt cctctagagt tttgatcagt tgtagacgtt
    15781 ggatgatgga agctagatca gtgtaagaat ccgttcccgt caagatatca gagatagcat
    15841 cgaagcgctc gacagtcaag gcgttctttt caatccctac attgccaggc tgaccatagc
    15901 gagcacgaag ttcttttccg atgatctccc aagggttttc gctgtctaaa tagccacgga
    15961 catcatacgc ccaactactg ttttgagcat cttcaacttc caaagcagga gtgaaaagga
    16021 aaggatcttg ttcaagaggg ataaaaagag ctagtacacg ctcatgagga tcactttcgt
    16081 atccggaaaa gtaagcgatg tggccagggt cgctgatata agccaattcg acttggtgtt
    16141 gtgccatcca ttgacgtagt tcattgattt ttacgttatt catttggcaa cctactttct
    16201 aaattaattt tgtattcaat aattgtacca ctgatttatt aaaagaccaa cgttctaaaa
    16261 actgaaaaaa gtaaaaattt tcatgaaaac agagataaaa cggttgcaat tcttgagatt
    16321 atttgatatt ctattttaga aatgtaagac gtattttcag aaaacatata aaatatgaat
    16381 aggagaacac aaatggaaaa gcaaacaatc actatctatg atgtagcgag agaggcaaat
    16441 gtttcgatgg ctactgtttc acgtgtcgta aatggcaatc caaacgtcaa accagcaaca
    16501 agaaaaaaag tcttggaagt tatcgatcgc ttggattatc gtccaaacgc agttgcgcgt
    16561 ggcttggcaa gtaagaaaac aacaacagtt ggggtaatca tccctgatgt cagcaatatg
    16621 ttctttgctt ctttagcacg tggtatcgat gatgtggcaa caatgtacaa atacaatatt
    16681 atcttagcaa attcagatgg taacgaccaa aaagaagtca atgtattgaa taacttactg
    16741 gctaagcaag tggacggcgt gatcttcatg ggtcaccata tcacagacga aatccgtgga
    16801 gaattttcac gttcaaaaac tcctgttgta ttagctggct ctattgatcc agatgaacaa
    16861 gtaggtagcg taaacattga ttatgtatca gcaacaaaag atgcagtaaa caaattggca
    16921 aaaagcggca ataaaaaaat cgcttttgtc agtggtgcgt tgatcgatcc tatcaatgga
    16981 caaaatcgtc tgaaaggcta taaagaagca ttaagcgaaa ataacctacc atatagcgaa
    17041 ggattgatct ttgaagcaca atacaacttc aaagatggtc tatctctagt cgatcggatc
    17101 cataatagcg gtgcaacagc tgtctatgtt tcagatgatg aattagccat cggtattttg
    17161 gatggtttat tagaccgtgg cgtgaaagta ccggaagaat tcgaaatcat cacaagtaac
    17221 aattcactac tgacagaagt agctcgtcct cgtttaacaa gtatcacaca accattatac
    17281 gatttagggg cggtatctat gcgcctattg acgaaaatga tgaataaaga agaagtcgaa
    17341 gaaaaaacga ttatcttgcc ttatggaatc gaagaaaaag gatctacaaa ataataaaag
    17401 gacaaccatt cagaggttgt gagcctgccg tttaactctg cgttacaagg agcaatttca
    17461 aaaaacagca tttcatgttt gatgaatatt gtgactcgtg attcggagtt ggcaggagaa
    17521 caccgtttat tcgggaaaag gggttatgac aaaattttgt ttaatccttt ttttttgtct
    17581 taaaaaagag agaaagtggt tgaaattaca tttatcgtat ataaaacaat ccgtgtatag
    17641 atgctgcatt atgttcacca ccatcaaaaa aataagggac tgtgacaata ctattgtcac
    17701 agtcccttat tactgtgtat tctattaaat caatcatctt tctcatctga ttctttggtt
    17761 gcttgattcg ctcttgcata agctgaagcg gtgttccagt aatctgtata gttttcatcg
    17821 gtaccgccaa cgccaaattt aaaggcgctt ttcttcggtc catttttcgc ccatagcgat
    17881 tcaactgttt ttcctggtgt ttggatggat tttttattga cagtaacttt tccaggtgtt
    17941 tgaccagtaa atccagatac ttttttcttc atcacatcag atgataattc gaatttctca
    18001 tcagtgccaa aaatgtcagg ttttgcttgg taagcttgat tgatcagatt ggcaagataa
    18061 ttagccgaac gtatccttgc tttgctgtcc attccagtat tgtcatcgtg ccctgcccag
    18121 ctactgatgg taatagacgg agtagagaca attagccatg aatctcggta ttcattggta
    18181 gaaccagttt ttccgaccca atctgctttt cctagatttc cgtttaagct tgagatggca
    18241 tctttgaatg gtgtagtgat ttttgcattg atcacactgc gcatcatgtc attcatgatc
    18301 gatgccgttg cttccgaata gatccggaca gagttgcttt cgtgtttata aattacattt
    18361 cctgcgttat ctgtgatgga atcgatgata tagccttctt catagacgcc gccgtttgct
    18421 aaagcctgaa atccattggt ctgttgaagc gtcgtgacat ctactgtacc taaaggagca
    18481 gattcaacgc cccaattgtc atttgccggg tagttcatct ttgccaagta gtgctcgtaa
    18541 gcatattgtt tcgatccacc ggaattcaac acatcttgat ataagtgata agccgggata
    18601 ttgttggacc attctagtga ctcacggacg gtttggaagg tgttcgatcc ttcgttagta
    18661 gcattgacga ttttctcgcc agcattttct ccttcttgcc aagttgttgc ataatctgat
    18721 acacgggatt ctgatccgat aagccccatg tcgattgcag gtccataaac aagaactggt
    18781 ttgattgatg agccagcttg acgttctgta tcgaaggcat ggttattttg attctgactg
    18841 taattccgtc cgccaacgaa tccgtagatg cggccagttc tgttatccat caatacattt
    18901 ccggtttcta cttgactgcc agcaccatca tctaacatgt atccataatt ttctacgcca
    18961 ttttgcaatg cagcatagac atctttatcg attgtcgaat ggattgtata tcctttattt
    19021 tggatcgttt gctgtgcctt ttgataataa gcgtcactga ccgatgaatc agacatatca
    19081 gcgttgtctt tttcagccaa ttgttgtgca atgattcttg ttgcttcatt catcacagta
    19141 taatacaaga attctctgtc agtctgttct gcgatttgtt gtggtagaaa gtcttttgta
    19201 aggtcatagg cttttgcttc ttcgtattgt tctttcgtaa tttggccttc acgatacata
    19261 ctgaataaaa caaaatcttt tctggcaagg ccggcagaaa gatcttcttt tagcgcacct
    19321 gtgttcgtgt atggactata cgtgatcggg ctttggggta atccagcgat ataagcagct
    19381 tgcggcagcg tcacatcttt tgcatctaca ccaaagattc ctcttgcagc ttcctggact
    19441 ccagcaatgt tttgtccctt attattacga ccaaatggtg agacattcaa atacgtagca
    19501 atgatctcat cttttgaaaa gtatttttct acttgtgcag aaagaatgat ctcgtttgct
    19561 ttacgtttga atgttgtttc atctgtaagg atctgctgtt tgactaattg ctgtgtcaaa
    19621 gttgatccac cagaagagcc aataccagta gcttcagata ctaatgctcg taaaacagct
    19681 ttaggaacgt aaccttggtg tttatcgaag tattcatcct ctgtgctgat aattgcagtt
    19741 ttcaataaag gtgaaatttt atcagatgaa atagtcgtgc gcatcagatc tgtctggatt
    19801 tttgatatct ctgtattatc tgcataaaca atctttgacg tttctgtaat gtttcctagt
    19861 tctgtctgca gtgctttttt agtcggcaat tgtgtgtctt cgacgagata ggcaaaatag
    19921 ccagcgccta ttccaatacc tagagctgcg aacatcaaaa gaagaacagt aataaaaaca
    19981 gtcaatgatt gaaaaactct aaaaataatc ttaggaacaa accatttttc tttttttctt
    20041 ctattctgtt tttttcgagt atttttgcgt ggcaaaaggg tcacctcaac taatggtttt
    20101 atttcgctaa ttatagcaaa taatagaaca aaaaaacaga caaggctgtt tttggcagga
    20161 atttcttttt taaaagagtt aaaacgtgag aaaatgatct tttttataaa agagttctta
    20221 agcttttctt tagagaaaat ttcagttact atggagaaca gggcaaagaa aaatcaatca
    20281 ttttctttgt atatcatctt accaatatat aggaattgtt agtaacaatt gcctttcaag
    20341 gaggaatcca tccatgttat taggctcaca cgtcagcatg agcggaaaga aaatgctgtt
    20401 aggagcagca gaagaagcag ccagttatgg atcttcgact tttatgatct atacaggcgc
    20461 ccctcaaaac actagaagaa aagccatcga agagatgaat attgatgccg gaaaagcgta
    20521 catggcagaa aacggtctaa caaatatcgt cgttcatgcc ccttatatca ttaatttggg
    20581 gaatacgatc aaaccagaaa tgtttccttt tgccgtccaa tttctgagag aagagattgt
    20641 tcgtgcggaa gctttaggcg ctactcaaat tacacttcac ccaggtgctc atgtaggggc
    20701 aggaacagaa gccggaattg ctagaattat tgaaggcttg aatgaagttt tgacaaaaga
    20761 acagacggca caaatcgctt tggagacaat ggcaggtaaa ggtacggaaa tcggtcgaac
    20821 atttgaggaa ttagcgcaaa tcatcgatgg agtaaaattg aatgaaaaat tatccgttac
    20881 ttttgacacc tgtcatacga atgatgccgg ttataatatt aaagaagact tttcaggtgt
    20941 aatggaagag tttgataaga tcatcgggtt agatcggctt aaagtactcc atatcaatga
    21001 ttctaaaaat ccgcaaggtt cgcataaaga ccggcacgcc aatattggtt ttggaacaat
    21061 cggattcgac acgctgaata agatcgtcca tgatccaatg tttgacaata tttcgaaaat
    21121 cttggaaact ccctatgtcg gcaaagataa aaagaaagct tacgcaccat atggaaaaga
    21181 aatcgccatg ttcaaagcac aaatattcga tccagaagtg tttcctgagt tattagcaga
    21241 agaagtgata ctctaagatt ttctatctga cagcagcaaa aaaggaccag gcacattgcc
    21301 ttgtcctttt ttgtttaaga aacaaaggag tgctttttgc agtctttttc atcatgcatc
    21361 ttctcccccc tctttttaaa tttagacaaa cagggtatac tggtagaaaa gtaaaaaaac
    21421 gaaaagtttc acaagcaagt ggcaaaacgt gattggaagg acgaaaagat gctgaacact
    21481 ttaaaaccct tgatcaacca actaaaaaag aaacatacat actttattct tggcatagcc
    21541 ctattattta caattattcg tttgtattta tatagtaaag caatctatgg aacagacatg
    21601 tcggcaacct atgatgacca gctgctgatt cgctatgctc aaaatatttt ggacggtaaa
    21661 tggctagggg agtatacgac tacaacactt tccaaaggaa tctcctacag cttattttta
    21721 gtacttgcac ataaactgca tctttcttat gcagttttgt tcggcatgtt cagtattttt
    21781 gccagtatat tggttgcact cgcgtttaaa ccgatcgtga agaacaagta tcttctttta
    21841 agtttctatt tttatttttt gttttctccg attagtttta cacatgaata ttccactcga
    21901 acgtatcgta atgccctcgt gattccggct gttgagatca ttatcgcttg tttactagct
    21961 atttattacc gtaaatatag ttccagcaaa aaaatgctgc cgtggttttt agggctagct
    22021 gtttcttttc ctttcttttg gttcattcgc gaagattcca tctggcttct tccttttact
    22081 gtagtcgcgt taggcatcag tttcgtccag atcttgctag gacaagactt ttctttcaaa
    22141 gaagcaaaga agttaaaaga acgaccattt ctcctttcga aacaagaatg gctgaaactt
    22201 tcattgtttt tactccctct agtcggtttc tccatcgtct atcagtggat cgaatataaa
    22261 aacgagacaa catatagtat tgccgccatc aatgaccgtt cgagtggcga atttggacgt
    22321 ttgatgaaac agctgatccg aatagatgac gaaacgaact taaataaaga aaacagtgag
    22381 atatgggtct cgcatgctgc attaaataaa gcattagacg catctcctac atttcatgct
    22441 gtttctactc gtattgacga attgtatacg actcatgcgt ggacccaagg tggaaaagta
    22501 aaagaattac caggagatat cattttttgg gcattgcgag atgtggtaag cgaatctggt
    22561 tattaccaaa acaatgcaaa agaaaccaat gatttttgga aaaaagtcaa tcaagaatta
    22621 gaagaagcct atcaaaaggg aactatcaaa aagaaaaaag aattctatct gatgggatca
    22681 ggggatggaa agacgatgaa tgatctgcca atcgtatttg cttttctgaa atcaggatat
    22741 gcctatgcat ggcgatacaa agatttccat caagggggga attatagttt cggtacgcaa
    22801 gaacaagtcg aacaggccca agaattattg aatcttccac taatggataa ttggatcgat
    22861 agcagtgatc cgagaacacc tgatttccag ttgacaaaaa cagcaaaagt cgcgaatgtc
    22921 atgataaaaa tttaccaagt tctggccatt cccgtgctga ttgcttcaat agcagggata
    22981 ttacttatga tactaggaac cgcatttgca aaagctgatc gtgcctatta tagttcctct
    23041 ttgattgtag tcaccggatt aatactgaca caattggttt ttcttttcgg cgtctcgtgg
    23101 ttttgttctt atgcgccaga aaaaaaggat tattttttaa gtgtctacac tggcgcaggc
    23161 gtgccattaa cgcaattcat cgtagtaaca agcatgctag ttttcagtaa attgaatctg
    23221 aaaaaagctt tatcttccaa ataaaaacat actaagatta gaggagaaca tcattgacga
    23281 atgatgttct cctctatttt ctatttttag attatagtga agagtgaaag aaagttcgaa
    23341 caaagccttg aggactatga gtccctatca aaaaccgaac ttctttactg tcattttaga
    23401 atcaggttta cgtatgttgg ggccatgagc ccgtgtatag gaaattggaa tcgaaatgaa
    23461 gcagtaaagt tctttcaaaa cttaaaaagg aggaaaacaa atgccttaca ttcttgcatt
    23521 agatgtttca atgggacaca gctacagtgt cctatacaaa gacgacacct gcttatttga
    23581 agacgagatc gaacacactc aaagaggatt tcatgcatta ctcgaagaga tccagcactt
    23641 gcctgaacgt ccattgattg tttttgaagc aacggggatt tattccagac cagtcgaaaa
    23701 gttctttcaa gatcatcact tttcttactg tttgttaaac ccgttagaag cgaaaaaaca
    23761 gatggaagaa aacaccttat gcagttggaa aacagataaa tcggatgccc atcggctcgc
    23821 acagactcat cttaaaaatc aacgtcagcc aaaagaagta caaagcaatt tttacttaga
    23881 gatgcgcgat ttagcccgtt tttatcaaga aattgagaag aaaatcactc gtctgcgcat
    23941 ggatttacac aactgccttc agttgacttt tccagagctt gaacagttct ttttaaacag
    24001 gctgacccct tacgcattga tattgatccg tctttttccc catccagatt ttgtattggc
    24061 atctactcgg acaaaaataa aaaataaact gatcaacgaa acacggaaaa aaatctccgc
    24121 gaatcgtgcc gagcaaaagg cagatcaaat catccactat gcacagtgtg cctatccagc
    24181 tgttgaaaaa gacagtatcc actgtcaaaa aacgatctat tacgctgaac ttctccaaga
    24241 tttactcgaa caaaaa
//
LOCUS       DAMEEU010000044        24210 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.045, whole genome shotgun sequence.
ACCESSION   DAMEEU010000044 DAMEEU010000000
VERSION     DAMEEU010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 24210)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24210)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24210
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.045"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(125..577)
                     /locus_tag="PB779_001710"
     CDS             complement(125..577)
                     /locus_tag="PB779_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739233.1"
                     /translation="MKSLEQEHMAFKQAMFKENIYLNHNYIRVSKACSPVLNMLGGGN
                     GLYHLLFVDVCWLIFLPDELVIVNEKITSKNEVFNYSLTRINYKEITKFSLEKVPFWG
                     EFCLKIKCNWKRMYFYIDGDDALTFGKTTFSSFNFQFLLKNNFYGLLK"
     gene            complement(584..1132)
                     /locus_tag="PB779_001711"
     CDS             complement(584..1132)
                     /locus_tag="PB779_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HDE0739234.1"
                     /translation="MKRIIKIFGVLGVFLLGLSTFVSTGTSVYATEKVNTVDLEIKNK
                     LVDELTFYFDTVGFLDEHGVYHIKDFGAIRERISQDNEQGRAARVFYEHIIVPRMEKV
                     DWKRYAGCVAINSLPGGGVAWAIGTQGDFIEALKAFNFEKAADLLLKIAEKQLGKAAA
                     KELAKVNIVAGIAAAAASCALE"
     gene            complement(1177..1509)
                     /locus_tag="PB779_001712"
     CDS             complement(1177..1509)
                     /locus_tag="PB779_001712"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739235.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRQEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLIWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(1523..1780)
                     /locus_tag="PB779_001713"
     CDS             complement(1523..1780)
                     /locus_tag="PB779_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739236.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KGYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(1975..2517)
                     /locus_tag="PB779_001714"
     CDS             complement(1975..2517)
                     /locus_tag="PB779_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739237.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLRTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQMQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDY
                     MTDRCIKDNSIDVDPHVQMKTTGKLYQVTQDIENPDQYLLFGEETMNKVTQFVLLQLK
                     VDQEAQKIDAIKIYYVRSAY"
     gene            complement(2538..3629)
                     /locus_tag="PB779_001715"
     CDS             complement(2538..3629)
                     /locus_tag="PB779_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDE0739238.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEHGGEATGLAVAFNGE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESAYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKACYDYYGFMVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYRGAMSIITSYNLTEYDTFAIKHWNSLPTKK
                     TSLIAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YNWTTYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSYGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(3637..5847)
                     /locus_tag="PB779_001716"
     CDS             complement(3637..5847)
                     /locus_tag="PB779_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739239.1"
                     /translation="MAYIKHKEKKWCVLFFLTIGFGLLFVGGLVYAAEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYILLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPVFDYMLMNTLKSFLGLMFQKSFYSVIILVAFLIY
                     NIVDDLIPMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGRQVVNPFELGGRSNQALPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQLSKQQGNNQRKPLLNKGIAFVGQSIPLPSGKVPVPQLTAAGSLS
                     QQIRQVKNQAKNGSYPAMQQLLNQYSVPNSSVATLSGNRSVQQPGQRSSESKPSISAP
                     KSLQPAFSSLDKPTEQSEKIEKDPKTLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(5863..8391)
                     /locus_tag="PB779_001717"
     CDS             complement(5863..8391)
                     /locus_tag="PB779_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HDE0739240.1"
                     /translation="MVLVKEPVKAFKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFHDVINLIWLDLAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRIPKEHKGLLQLEDELGSSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEHKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATVIQQLHTIIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAVGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVDYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILNHLRLEVNEANLAEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQVEEQDTLIMQ"
     gene            complement(8443..8853)
                     /locus_tag="PB779_001718"
     CDS             complement(8443..8853)
                     /locus_tag="PB779_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739241.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFYIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYMI
                     RMMNGDCVYYNWDKVSNNALEELLFVNKYVYLED"
     gene            complement(8866..9084)
                     /locus_tag="PB779_001719"
     CDS             complement(8866..9084)
                     /locus_tag="PB779_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739242.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(9081..10073)
                     /locus_tag="PB779_001720"
     CDS             complement(9081..10073)
                     /locus_tag="PB779_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HDE0739243.1"
                     /translation="MKKRQLRRKEKVYTEKVPKQKKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSRSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQETLKKEFYAQNFIQEPGSVSGVRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMNPESKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKPFIVKATVVFRDGDTSLLQKEQMTIVITKKTNQYYVEKLTHNWLDRKGEERK"
     gene            complement(10152..11063)
                     /locus_tag="PB779_001721"
     CDS             complement(10152..11063)
                     /locus_tag="PB779_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDE0739244.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLPDVETELNGGTTEKPAEPEQLQSEKPEKEPVTPEPEFPESTLPTDSIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSEKNTDSSSTEQPTMSSTSEEQKEEPKQPVEKSEAIPK
                     ENKPIVPAKEVTVSVTPSGEITTNTSQGMSVPIVTSNVEELTHIPTPTTPLKVAGDQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEIKTADGKTKVLPKTGEEIHVALS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(11082..11426)
                     /locus_tag="PB779_001722"
     CDS             complement(11082..11426)
                     /locus_tag="PB779_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739245.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLYPRMERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(11446..12002)
                     /locus_tag="PB779_001723"
                     /pseudo
     CDS             complement(11446..12002)
                     /locus_tag="PB779_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12083..12583)
                     /locus_tag="PB779_001724"
     CDS             complement(12083..12583)
                     /locus_tag="PB779_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739246.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPEEYPIEKHELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPIDFLKKC
                     HLRILP"
     gene            complement(12584..13129)
                     /locus_tag="PB779_001725"
     CDS             complement(12584..13129)
                     /locus_tag="PB779_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739247.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGRLEFIRFYRFSLPIPAILAVK
                     KGCDKMKIYENCVAALSSEKPLMEEISLVTVTWEMSRQPTEEQTYLSLEEIEIELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(13126..14382)
                     /locus_tag="PB779_001726"
     CDS             complement(13126..14382)
                     /locus_tag="PB779_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HDE0739248.1"
                     /translation="MTPIELKSYRKKLSAIHNISGDKKPLSQARFAQLMGCSKDYIRK
                     MEQGKRKIPEDFEQRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKTVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKRTVTENVLVQFSGQGCREYEEVMREQQTD
                     WRTWLYSIWKNQGKLEAGYTRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKRFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISELEAL
                     TKYGIYNRYELRLANEKATQAVEAFILGDSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDKRWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIDNAELNDEQQNYLEWMGTSGGKIA"
     gene            complement(14743..15054)
                     /locus_tag="PB779_001727"
     CDS             complement(14743..15054)
                     /locus_tag="PB779_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739249.1"
                     /translation="MAESCYYRVATAIRMINPSLSSRTFYDWLNRIEQVTDYRFLRKE
                     RVFTGKVINQVLLTKKDIERLTRLYHYRVDLEEDLTLSIYRVFSPEKYSEITKLDHLI
                     L"
     gene            complement(15077..16387)
                     /locus_tag="PB779_001728"
     CDS             complement(15077..16387)
                     /locus_tag="PB779_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
                     /protein_id="HDE0739250.1"
                     /translation="MYLIPGISIVLYLLLVSGLILGLMHWSRLKEGYFASVYWRQLLV
                     RMLIDNRFVYTKKQVSEKQTREKMRLPKVYFYQKKQELVVSFPLDGGRFHERFLKMGH
                     LLSEVFLRDLIREEREKARINYVFLSDSGRIPIDQCIAENGRIHLMKTLDWVYDQSPN
                     MLIAGAIGGGKTYLLYSLIQACLSVGTVDICDGKAADLAALGDVDVFKGHVFYKINEE
                     MIICLRNALKEMNQRYAYMKTMKDPKYEPGKNYAYYGLPPHFIFFDEWAAFYGSLDME
                     ARNRVDKLIQPLVLKGRQAGMYIILAMQRPDAEYFPSGVRDNLTFRISVGRLSPIGYL
                     MTFGEDFKNKPFYNKDQPGRGYAFPGFDVPVEFFAPFVYKDYHFIKEFEKFTEMIVYD
                     FTVKEDSQDQTMGDDNQLLQEQLERQMYLAKDPKGTSFSDAHIL"
     gene            complement(17001..17453)
                     /locus_tag="PB779_001729"
     CDS             complement(17001..17453)
                     /locus_tag="PB779_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739251.1"
                     /translation="MGLKFPNNYDITEALDETCLGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNPNMKQSQEKGLDQKQPSVDSKEKEKK"
     gene            complement(17455..17820)
                     /locus_tag="PB779_001730"
     CDS             complement(17455..17820)
                     /locus_tag="PB779_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739252.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIGEVL"
     gene            complement(17919..22202)
                     /locus_tag="PB779_001731"
     CDS             complement(17919..22202)
                     /locus_tag="PB779_001731"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HDE0739253.1"
                     /translation="MYAKTKMNWLKALALVAFSQFCFLVGTAQAHAEETTAIQPTMEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPGT
                     SQPVEETASITTPASETSTLEGEKAAEATPSVQPESSEKQAEEKKRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKPNKESTASIENQKKKEQNIPKTGTPTLLVTVP
                     TNRSVRVRRATNAAVLGGRKIDWGENIGVTSSPNNLNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALKNYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLINNFGEKATFNNQTHTVKIGETLKVKNKNDFLKYV
                     KDIQKPKGVNVSIHGNEVWITVTKEAPDKAKIQLNKIKVQGAPLAYRRPGAQTIGVLH
                     PTEPNASVINLQILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KKINGKVQAEIKDLDPGKYVLKEIKAPKGYVLSDEAIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKVANKDLVDSTNPDNKPKLAGIEITLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKDRYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVN
                     FTLYNGKNQAIGEYTTDQNGEILVKGLVADDYYFLENAPLESFQPNTDKQAFTVAFKQ
                     NAPDDGETLVVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQDGKEITSTLAFIADKVNGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAAHADINDEAQSVKVNNPTVHTTAVFEDGLTVADPTGLFTLNDTVEITE
                     ILPGKAYLVKGILMDKATGEPLLVHGNTVETSVGFIAKAENETVIVPFTFDLTGINGR
                     EIVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLVVGKTYTVNGVLMDKVTEKPVLVDGKEVTSTLTFVAETTDGTVNLDFILD
                     ARALRGKEVVVFEDLFREGVLLASHADITDNDQTIKISNPTITTKATNKNGGKEILAL
                     PNQTVLEWVKVDGLAIGQIYRLIVQGYLTPDGTPFEGTHAEKVFAADKEMMEFLFEFL
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQIVEAPKPPQPVK
                     PEQRVKPATVVPMLPKTGEQTSSILMVLGLVVLVIALGITLYKVRKAKD"
     gene            complement(22349..22588)
                     /locus_tag="PB779_001732"
     CDS             complement(22349..22588)
                     /locus_tag="PB779_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739254.1"
                     /translation="MIDISLPEDLKPDPVTIGNSVMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMRFGDGEVAKKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(22678..22950)
                     /locus_tag="PB779_001733"
     CDS             complement(22678..22950)
                     /locus_tag="PB779_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739255.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(23033..23284)
                     /locus_tag="PB779_001734"
     CDS             complement(23033..23284)
                     /locus_tag="PB779_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739256.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFFESDIGWDDHEEVYGKFILRKGNSYTNGEA"
BASE COUNT         7171 a         5230 c         3518 g         8291 t
ORIGIN      
        1 gttcttctaa acaatcatct atactcatat aatcactcca ctaattaatc tccccaaaaa
       61 gacacagcat taagagatat accaacacaa cagtgcaaat aactctacat cttccttcgc
      121 aaccttattt caataaacca taaaaattat tttttaatag aaactgaaaa ttaaaactag
      181 aaaaagtagt tttaccgaat gtaagagcat catcaccatc aatatagaaa tacattcttt
      241 tccagttaca tttaattttt aaacaaaatt ctccccaaaa aggaactttt tctagtgaaa
      301 acttggtaat ctctttgtaa ttaattcttg ttaaagaata attaaacact tcatttttac
      361 ttgttatttt ttcattgact ataactagtt catctggtaa aaaaattaac caacaaacat
      421 cgacaaacag taaatgatat aatccatttc cacctccaag catattcaat actggtgaac
      481 atgccttaga aacacgaata tagttatggt ttaaatagat attttcttta aacattgctt
      541 gtttaaaagc catatgctct tgttctaaac ttttcataaa cttttactct aatgcacagc
      601 tagcagcagc tgctgcaatt cctgctacaa tatttacctt agctaactct ttagctgcag
      661 cttttcctaa ttgtttttct gcaattttta ataataaatc cgcagctttt tcaaaattaa
      721 aagcttttaa tgcttcaata aaatctccct gcgtacctat agcccaagcc actcctcctc
      781 caggaagaga attaatggct acacatccag catatcgttt ccaatcaact ttctccattc
      841 taggaacaat aatatgttca taaaagactc ttgctgctct tccttgttcg ttatcttgac
      901 tgattcgttc acgaatagca ccaaaatcct ttatatggta tacaccatgt tcgtctaaaa
      961 aaccaactgt atcaaaataa aaagttaatt catctactaa tttattcttt atttctaaat
     1021 caactgtatt cactttttct gtggcataca cacttgttcc agtactaaca aaagtactta
     1081 aacctaataa gaaaacacct aaaacaccaa atattttaat tattcttttc ataatttctc
     1141 ctccataaaa aataagttac tttttaaata tcttgtttat gaattcattc cccaaaggcc
     1201 ttttaagatt gatacagcag tccgttcact tcttttagac ttgtcataca agtcttttaa
     1261 atgatcccat atcagactag tttgtctatc tagcttcaat ccattaaacg ctaatgaacg
     1321 gttcattttt tctattactt tagataaagc tacagaaatt tttatacctt cacaacgcgc
     1381 atcttggatt tcaataatag tatcatcaat tagtttttga atttcttgcc tatcaacata
     1441 ttcaatctta gaaagagaat cttttaaagc tactaatgat tcaacgattt cttttttctc
     1501 ttcagacatt ttcttcctcc ttctagtgac ccgtaaagcc atgtagagca gagtccattg
     1561 aaccagtaat tacactatct acaacgccat tccaatttac tctacatttt ccatttttca
     1621 gatttgtcgg tccatacgga tagccttttt gacattcaat gttcggatta taccagatag
     1681 gattatacca ttcagccgca gaagcagatt cagtcgatac aaacaatccc acaccaacaa
     1741 atccaataca catcacacta tagccaatta gttttttcat ctcgtatcca tctcctaaaa
     1801 aatagaatag ttcttatagt tattcataag acatattttt tccgtttttg ttttatcctt
     1861 tctgtcctat aacaactttt ttcaagtaaa gaatgacata gtttttctta aaaaaacagt
     1921 ctgttttttt ctatttcttc ggtgtataat aaatatgagt gttcattttt tattttaata
     1981 cgcactccgt acataataaa tcttgatcgc atcaatcttt tgagcttctt gatctacttt
     2041 caattgaagt aatacaaatt gagtaacctt attcattgtt tcttctccaa ataacaaata
     2101 ttgatccgga ttctctatat cttgtgtcac ctggtaaagt ttcccagttg ttttcatttg
     2161 tacatgcggg tctacatcaa tactattgtc tttaatacaa cgatctgtca tatagtccct
     2221 cacagcttga ttgcgtttat aaacatctgt gaaattactc cattttctag caaaatcttt
     2281 taagaaattt tttgtcattt catctatttg catttgttgc gctgtctcgt cttctaatga
     2341 accaatttga ctgttacttt cagtactttg aagagttcca cttgtttctt ttactgcttc
     2401 gattgtttct tctgtcgttc tcaattgtgt tttttgtttt tcagaagaaa accaatgaca
     2461 accagtaaga cctatcaaac ataaccaact aaatactaaa attatccctt ttttcacgtt
     2521 tctagtcact gcctttctta tttcacctta cgaaccagac tacgaatttt tgtttgattg
     2581 tacgtgcgtt gataccgagc cataatccgt ccttgctcgg cattctgttc cacactagag
     2641 aaatgttgtc cgccatatga aacatctgtt ataattccgg tgtgaccata gattccagga
     2701 gacaatgcac cacctgcttg ccaattcacc acatctcctg cttgtaaatc acttggtttt
     2761 gggttcatga ttacttgcca accataggtt gtccagttat aatcttcccc tattaacatc
     2821 gcaaacatgt gtccagaacc cattaactgt gggccaccta attgagatac ataccatgcc
     2881 gtaccaccat aacattcccc attatttacg gatcgtccaa tgatccgatc caaaaccttc
     2941 gcattgcctt tactttttcc tgcaataagc gaagtttttt ttgttggtag gctattccaa
     3001 tgcttgatcg caaaagtatc atattccgtt aagttatagg acgttatgat actcattgct
     3061 cctcgataat acggactccc ttcggtaata cctgctgccg catagcctcc acgacctaga
     3121 atcaataaac aacttccagg atctttattg cccacacatt gattaaagtt gctttggctc
     3181 gccaccataa agccataata gtcataacaa gcttttaagt tcggaaactt catatagaaa
     3241 ccaccttcag aaccaccaat tccacgtgca gaaccttgtg ggtagggaca accaggaaac
     3301 caggtaatcc caaaaaagtt cgtatcgttt cttccagatt gtgactgtcc ataagctgat
     3361 tcatagccta attgagaaag aatcacactc ggtaataact gatactttac agctgcacca
     3421 actgctgctt gcgcatgttc atctgtgatt ggaccacgtc ctttaatctc tgaaaaaatc
     3481 ggtaatcctt cggtatattc cccattaaaa gcgacagcta gacctgtagc ttctcctcca
     3541 tgctcagaaa gttctcctga aaaaaagaat ggcaatagaa aaaagggaag aataaagaaa
     3601 agaagacaac ctagacaccc tttcttcatt tcttcctcat cctttcttcg ataatggttt
     3661 ttggactgtt cgtccttttg gtaaagtaaa atcagttcct ggttttgcgt ccaaaatcgg
     3721 cagtgtttta ggatcctttt ctattttttc cgattgctct gttggcttat ctaaagaaga
     3781 aaatgcaggt tgtaacgatt ttggtgcgga aatcgacggt ttactttcag acgaacgttg
     3841 ccccggttgt tgcacagaac gatttcctga tagagtggct accgacgaat taggaacaga
     3901 gtattggttc aataactgct gcattgctgg ataactccca tttttcgcct gatttttcac
     3961 ttggcgaatc tgttgtgaaa gagaaccagc agctgttaat tgtggcacgg gtacttttcc
     4021 agaaggcaac ggaatcgatt gaccaacaaa agcgatacct ttatttaaca atggttttct
     4081 ttgattattc ccttgttgct tactcaattg tgccaatgat tgtacctgtt gttttggtct
     4141 tactgaattc atggacgaat ttggaatcaa accatttgaa agaccagaat tccactctgt
     4201 tttcgatttg gtagaagaca tttcaggctc taccccatga taacgaacat gacgaccact
     4261 ataaggcaag gcttgatttg aacgcccacc tagttcaaag ggattaacca cttgcctccc
     4321 ttttaccgat tcttgtggtg tacgtttttg ttgaaacttt tgaaatccat gtatcgctgc
     4381 agaagcgagt ggattcgttg ctcgatacac attccctgct aatcctgcac ctttgattgc
     4441 caaattttgt ccagcagttg atagttgacc aggcagttgt ttcatttgag acaaagaatg
     4501 acttgctatg tttttcgtgt tgtttatagt ttgatctgca gctcctaacc ctagtttctt
     4561 taataaatct ttccgtttta caatgagtaa aattgatagg agtgctttga caaacatatt
     4621 tcctaaaaaa ccaaaaacag tattcattgg aattaaatcg tctactatgt tatagatcaa
     4681 aaatgccacc aaaataatca cactgtaaaa agatttttga aacatcaagc ccaaaaagga
     4741 ctttaaggta ttcatgagca tataatcaaa tactggaaca aaagaagcga gtaatgaaaa
     4801 aggaatcaca agtaataaac acaacaccaa catttgaaag ataaaacgaa tcatgccaat
     4861 cactacaagt ggtaatccaa tacttagatt aagcaatggc accatagaac caacgactgc
     4921 tttataaaca gctttagttg gttgaatata gacacgataa gccttctttt tccctctatc
     4981 ttctcctgca gcagtggtca cttttgtctc aatatcagat aattcttcac ttgacgcttc
     5041 cttggctaga aattcttgtg gttcaatctc tgcttgatac aattcttcta aatttgttgt
     5101 cccataattt aacaatatat acggatcaac aacagccgct ttataataaa gttggcgcac
     5161 tttttgaatg gcttcctttt gtgtcgttgg cactaaaaca ccattgacat cttttgtcgc
     5221 caattcatct agactatttg tagcagaaaa aataaagcct tctacctcca cggacaaatc
     5281 atttaaccct ttggtaaaag cttctccttt actaggtacg ttactaccat agccaaacca
     5341 aaccattgaa aaaatgacaa cgaagagaaa tcgaataaac accatttttg cgtaatgttt
     5401 ccctctaaat atacgaagag taaatagata taacacatac aagacgacaa tccccgcacc
     5461 aataggatcg tatatttttg aataaatagt atccgaaaaa gtgaaaaact ggtgaattaa
     5521 ctcgttcatt gcagctcctt catagagctt ctcaatgaca aaatcaaggc cttgccaaat
     5581 caatttactt aaactaaaga acatattcgt catcattttt agaaaatctg tgccatttgc
     5641 cccaaataac attttgccta atgaaaattc actatcagat aaataagaag aaaaggtatc
     5701 aatatgaaat ttcccaatct catagatcga ttgatccacc tgcttttctg ccgcatacac
     5761 caatccacca acaaaaagca gtccgaatcc aatcgttaaa aaaaacaaaa cgcaccattt
     5821 cttttcctta tgctttatat aagccattgt ttcacctcat ttctattgca tgattaacgt
     5881 atcctgttct tctacttgag agtgacttgt tttttccgtt gtttgtaatg cagcggtcat
     5941 ttcttcaaac aaactgtgta cattgagttt tcctacacgt ccatagggat ctaacatcca
     6001 acactgtcct ttaatcatgt ggctcatttc agctaagttc gcttcattta cttccaaacg
     6061 taaatgattc aaaatctttt ctcgctcact gtcttcatca aaagcaaaga cgacaccaaa
     6121 attccctttt tctttatctg aacctaagtc accaataaat tgtgtatcta acactaattg
     6181 attcatctgg gaacgcccca cacgtgccat tgctgcaata atactacgtc ctgcgttcga
     6241 attattaaat acccatgctt ctgtaaaata aatcgctgtt ttcttactac tatctcgttt
     6301 tccaaacatt tcacaaaaac gacctaaact aatcatcaaa cacaaagact ttcgatccgc
     6361 atctgtatat agttctggtc ggacattgtc atttggtaat ttcaaatctt ggatctctaa
     6421 aatcgttgtt ttggcattaa agtctaatcc cgggttttct ccataagaaa atcctaaacg
     6481 taaaatcgaa tcttctaccg tcaagcgtaa aaactcacca tattctcgaa cctctttttg
     6541 ttccatttgt tctaaatagt cgaccacatg catcaagcca acttgttgtc cggcttcttt
     6601 ttgaactaaa acttcttgga ttccctttaa taccgcccct tttaaaaggt gattggtacc
     6661 taacggactt aactcatcaa tcatatcctg ggctacttgt ttcgcatcta ctcgggataa
     6721 acaaacaatt ggatctaata caccataatt acggggattt gtagcatcta acgtgacata
     6781 actcattttt tgcaaatgtt ctacaaacaa agggtaatgt ttctgataat acgggtcttg
     6841 aatgagtttc gtaaaccatt tgcgcttttc tcctttggga tccacaaata aactttgtac
     6901 attcataaac gaactataca aaaagagcaa gccaactaaa aaggtcttcc ctttaccggt
     6961 ttttccagtt actgctacat gaggcgcatc aaacaacgca cctttgattc cttccgcaat
     7021 ggctagaaga ttcaaaaaga caaaacgatt tgacgcataa attaattctt ctaatggtgt
     7081 tttttctcct cgagaaccac catcccctaa tgtatcttgc cgaccaatat accagccgga
     7141 ttccatacct aattctgata ctgctgaaaa caaccattcg ccaactgctt ctacagttgt
     7201 tcggtgcttc caatgtaact gccgtcccaa tggttgccct aataaacatt tatagaacaa
     7261 ttctcgttga tcattttttg cacggtggat atggataatc gtatgaagtt gttgaataac
     7321 cgttgcacta ttttgacgaa cttcttcaac cgtttgaccg tatacaataa aacatgcgat
     7381 ccaatcgacg acaggttgcc cattatctac tcgttgcttt aaatgtttta ctaatcctcg
     7441 aacagttaat aagcgttcac taggttcttc atcattttga accaattcct tatgctctgt
     7501 tttgaaccgt tccgatagcc aattcagttt taaaccaata cctccctgtc ctttcaagcg
     7561 tggatagtga attttcattc gcaattctgc tgggaaagaa agatcctgag caaattgaaa
     7621 tagatcacaa tttctcatat tttcaggtgt ttccccaata ggcaacaatg ctaaataact
     7681 actccctaac tcatcttcta attgaagaag gcctttatgt tccttcggta tacgtacata
     7741 cgttccttga ttgtctttca gtacttccca attattttgt tcttctactt tgtgagccat
     7801 tcctcgaata tattgcagac gattgagata caacagctct ttttttacta agggacgaat
     7861 agaaaagcta taaagtaatt gtgtcacttc ttttacataa ggatcacttt cagaaaacaa
     7921 agtttccaaa tcatctactt ctaatccaaa taagcgtgct aaacttcctg ctaaatctaa
     7981 ccagattaga tttattacat catgaaaact ctccaccgtt gctttttctt tgactttgat
     8041 tcctaaaata aatgaaggac gatagacttg accttctcgt tccaacaatg tcactgtttc
     8101 ttttgcataa tacgcaccaa ttgcttgact atcgggagaa aatccctttc ctaatgtgtc
     8161 aaacttcgtc cgtaaattca ttgttcgtgg atacatcacc aactccacat cttcataatc
     8221 tgctaaaagc aacagtaaac gagccatcat ttcttttatt tcctgtgtct tttttggtgt
     8281 gttttttgaa attgttcgtg gaaaaacatg atagtaggcc cagatacaat cctctccatt
     8341 taacaaacaa tttttcttga atgcttttac tggttctttt acaagcacca atgaatttca
     8401 cctcccaata aaaaaggaac aaccagttga ttgtcccttt ttctaatcct ctaaataaac
     8461 atacttattc acaaaaagta attcttccaa tgcattgttt gataccttgt cccagttata
     8521 atacacacaa tcaccattca tcatacgaat catataacaa aaccaatccc ataaataaaa
     8581 atgcactttt tttccatcag gttttagttt tgccagtgct aacacacata aataggggag
     8641 tcctatataa aaaacaactc ctgctggtgg aaaaaaagaa atgacccaac caataaatga
     8701 acgtaaaaat aaatattcaa agattacgac caacaaaaaa gttgctgcat tgactaatgc
     8761 aactggaaat ggaagacgcc aattgcttgt aatctgttgt acgcgataag gttccgcata
     8821 aacaatcgaa taatcataag gttcccaatc cacttcacta tcctcctaat ccataaataa
     8881 tttttcaatg attttaccaa acgcatcaaa tacacgtgtt ggatcattta agaagaaata
     8941 aactgcggca cctgctgcga tagatattaa tgcatttcct acttttgatt tcataaaatt
     9001 tcgcaatccc agataaacaa ccaccattat taaaaaatag ccaccttgcg ttaatataaa
     9061 atctacaatt cccttcagtg tcatttccgt tcttctcctt tcctatccaa ccaattatgt
     9121 gttaattttt caacataata ctgatttgtt tttttcgtaa tgacaatcgt catttgttct
     9181 ttttgtaaaa gtgacgtatc accatctcga aagacgaccg ttgcttttac aataaaaggt
     9241 tttttcgttt ctttataacg caatactttc atctctactt gatcaacttt agctgtttga
     9301 ttgagtcctt caggttcttt catcatgtat gacatatctt ttgcattgtt tttcgcatac
     9361 ttatctaaga aatcttccac aaatccttca acatctttcg cttccgacgc atcaaccgtt
     9421 tcgtataatg tgtcatcata agtaatcatt cgttgttttt ctgtattctt tggtagtgcc
     9481 gtaaaataag gataagcaat aatacgacag cccttgtttg aaatagaaaa gggaagattg
     9541 agtacttgtg tgattgtcac acttgtttct ttcttactct ctggattcat cgagcgaata
     9601 tcataagtta ctttataact agcagttgga atggtttcaa tttcttttaa tccaataaac
     9661 gaagcagcag ttaattttcg aacacctgaa acacttcctg gttcttgaat aaagttttgt
     9721 gcataaaact ctttttttaa tgtttcttga cgttgttgtt cttgttcatg attatcgaat
     9781 gtattcatat acaaagcaac aaaacgattc ataaaggatt caatttcagg tgtgtacgtt
     9841 aattctgacc gactttgtac ttctttcttt tgtaattgtt ggatttcatc tttcaaaaac
     9901 gacacttgaa ccttcgtttt catggattga aaaaatgcca agccccctga aaaacaaaga
     9961 aataaaacca aacaccaaat ccatttcact gctttttttg aatggatttt cttttgcttc
    10021 ggtactttct ctgtataaac tttttctttc cgccgtagtt gtcgtttttt cataagctac
    10081 tccttctagt atgtttttac tagtacgtac gattgacaac gataagcttg tttttctgaa
    10141 aaatagtcca ttcaattacc ctcattttct attccttttc tctttctttt atatccaaca
    10201 aatccagcaa tacttgtcaa cactcctcct agaacagaaa gtgcaacatg tatttcttca
    10261 ccagtctttg gtaagacttt tgtttttcca tctgctgttt tgatttcaat attgccactt
    10321 ggaagtttct ttacaggaat cgacaaatcc tttaccaaat tcccttcact atcttggatt
    10381 aatggaatac catcttttac accaacaatt gtttgatcac ctgctacttt taatggggtg
    10441 gttggtgttg gaatatgggt caattcctct acattactag tgacaatcgg tacactcatt
    10501 ccttgagaag tattcgtcgt aatttcaccg cttggggtta ccgatactgt gacttctttt
    10561 gctggaacaa taggtttatt ttcttttgga attgcttctg atttttcaac aggttgtttc
    10621 ggttcttctt tttgttcttc actggtagac gacatcgttg gctgttccgt acttgacgaa
    10681 tcagtattct tttcagaaga actggttgtt cctgattgtt ccggagttgt gactatactt
    10741 gaatccgttg ttgttgaact atgcacacct tcttcttcga tcgaatcagt cggtaaagtt
    10801 gattcaggaa actctggttc tggtgtcact ggctcttttt caggtttctc tgactgcaat
    10861 tgttcaggtt ctgctggttt ttccgttgtt cctccattta gctctgtctc aacatctggt
    10921 aatccttccc ctggcaatgt ttctacaatt tctgacttag gtgtttctac agtttcatct
    10981 gcataaacca atgaactccc taattgaaac gaaaataatg aaattcctag tgttgttacg
    11041 actgctaatg ttgttttttt catgattatt cctccaattt tttatgcaat tcgtgttttg
    11101 ttcatagacg ccgcactaat attatctgaa cgataaaaga actcccgtcc gttttcttct
    11161 aacccaacat atggattatt tttgaataat tgaatcaata gttcactggt gttgtatttt
    11221 ggatagtttg caaaaaaata atactgtgct tgtcgcccat ccgaaaattc aacaagtaat
    11281 tcataacgat accgcttcaa tccttttcgt tgttttaaag gatctctata ccaacttgtc
    11341 catcgttcca ttcgtggata gagatagaca cgatacacat agaacaatgc cataccacat
    11401 accaccaaaa ataataatcg ccacataaaa attccccctt ttcttctacc tttcttgaat
    11461 catcgaacat tcataccctc tatagagatt tgaaaaatcc atcatcaatt gttcatataa
    11521 acgttgttgc aaatagcgat tgtttcgaat acataattct tcatagccat caatcacttg
    11581 atcttctttt tcatagcatc ttgtagctct atgacgctca gcttgcatga cataaccaaa
    11641 ctctgcacca tatcgttcta ctgttaataa ctgttgacta cgcaataatg caatataaca
    11701 atcacaaaaa tgttcaaccg acatttgatt tttctcacgt ttgtgaaata ggtattcttt
    11761 agaaagcaca ttattcgtta aacaatctga taaatagcga taatctggcg gtcggttatt
    11821 ttcatctgtg aatttttccc ataataaact gatttttatt cgttcagcgg ctagatagtc
    11881 ttgttcgcgt ggataaaatt catcaatcgc acaaagtttt ttatcacctg aataaacaaa
    11941 tccatataat gcgaaacgaa ctcttccttt tcaattggct ctcctaaaaa ttccagtgac
    12001 ataccatctt ctccttccta aaaaaaataa aaaagcagaa accgatttgg cttctacttt
    12061 tctttccttt tatagctctt ttttacggaa gaatccgcaa atgacatttt ttcaaaaaat
    12121 caatcggcac aagttcacga aaacttggag caattttgga tagaatcact tccccatctt
    12181 gtaaaataca atcataaaaa tcatcagtta cttgatactt acgcttctta caataattga
    12241 taaaatagta gcgatcattt tctatttcca ttcgttgttc tactaagcgc atacgaacat
    12301 catcatagaa ataagccaca aatcgccctt caagttcatg tttttcaatg ggatactctt
    12361 ctggtaacaa tctatttttt cgtcgtttat acattgctgg ataccttaga agaagttcat
    12421 ctaaacgtct gtcagtatat ggtaactgac gaatcaacga ttctaatcgt tctttataca
    12481 gatagaataa ttggcgcaag caatagtgta ccgcctctgg attttctaat actgttggat
    12541 cacgtgacca atacgcacca acataaatca taattttttt catttagaca atcacaccag
    12601 caatactaat gaccgatcca caataggtag aacaagtggc atagcgacca atttcctcta
    12661 attctatctc aatctcttct aaagaaagat atgtctgttc ttctgttggc tggcgactca
    12721 tttcccaagt gacagtcacc aatgaaattt cttccataag aggtttttcg ctgctaagtg
    12781 ctgccacaca gttttcatat atcttcattt tatcgcagcc ttttttaacc gctaaaatcg
    12841 caggtattgg caatgaaaat cgataaaagc gaatgaattc tagccttcct ttccttcggc
    12901 taaattccaa ctcttcgagt tcttgttcgt atcccttacg aacttctaat aagcgtgcaa
    12961 tttcttgcca gttctctttt tcctgataac gtccagcttt taccgcttgt tcaatataag
    13021 gaactcgaaa acgaaaataa gacaaatcaa ccatcttttc atttaatgct tcgattgcag
    13081 cctttaaatc caacaggcgc agccattctg ttgtcgtata tgcattcatg caattttccc
    13141 tcctgacgtt cccatccatt ctagatagtt ttgttgctcg tcatttagtt cggcattatc
    13201 aatcccttct tgtacaaagt ctcttcctaa aatacgatct gcttcttgta acaactttaa
    13261 tgtcggagct acttgtttca aaaaccagcg ttctgaacga tctaatgaga atttttctgg
    13321 ctttactgta aaatccaatt cttccatcga acgaaataat tttgcccatc gtttatcaac
    13381 aatccgtgca tcactttcca gtctatccca aacaataagt tttgcattaa ttaaaccaac
    13441 gccaatctct cctaaacgtt tcggtgaatc acctaaaata aatgcttcta ctgcttgtgt
    13501 tgctttctca ttggctaacc gtaactcata tcgattataa ataccatatt tcgttaatgc
    13561 ttctaattct gaaatttttt ctcggttcgc aatttcaaaa cgtttctcat aaaaattaaa
    13621 aaagagagga ctctttcgcg atccaaaata caaagataat ccttcacttc gaaaatagcc
    13681 atcatctaaa aaacaaccgc caatattctg gaatctctta aagtccattt ctaataaacc
    13741 tgctttttgt ttttctagta attcaaagag atcgaaatgt tcttccgttt ccaatcccca
    13801 aagttcatct aacgcaatat cgaatcggct acattgcaca cgtgtataac cagcttccaa
    13861 ctttccttga tttttccaaa tggaatatag ccatgttcgc caatctgttt gttgttcacg
    13921 catgacttcc tcatattccc ggcaaccttg tcctgaaaat tgcacaagta cattttctgt
    13981 tacagttcgt tttgaatgcc agaacaccca gatattccca cgaacagaaa gacagtcaaa
    14041 aagatacaag cccgttggac gtgtttcaaa ttctgtcaga tccattcgta atacacgttg
    14101 aatcactgtt ttgtagtctg tcccaaaaaa ggaaagacgc aaataatcaa tcattgctcg
    14161 aagatctatt ccgcttttca tatacaatcg aaagcgttcc ttgattcgtt gttcaaaatc
    14221 ctctgggatt tttcttttcc cttgttccat ctttctaatg taatcttttg agcagcccat
    14281 caattgcgca aatcttgctt gtgatagcgg ctttttatct ccacttatat tatgaattgc
    14341 acttaacttc tttctgtagc tttttagctc aatcggtgtc attttctcgc tccttttata
    14401 aaataacaaa atcgattttt tttaaccctt tagaaacacc gatatatcaa ctagtccccc
    14461 tcgttttttg ggaaaagtag tacaactgct gaccttagat aatcacttga tacaaaaggg
    14521 tttataaaac ttttttctat gtgttatgtt atttctgccc cccatattat atatcggggg
    14581 gctttacaca aagaggccgt gcgcaagcgc acgacctctt tgtgagctgc acacgctgct
    14641 agcgagtgcg cattataggc ccatgcttcg cagccttaat gcgcaccgcc aggcagagtg
    14701 cggctaccag actacgtcta gagccctccc gatagataat aactacaaaa ttaaatgatc
    14761 taattttgtt atttcactat atttttcagg agaaaaaacg cgataaattg acaaagttaa
    14821 atcctcttct aaatctactc gataatgata caatcgagtc aatcgttcta tatctttttt
    14881 cgttagcaat acttgattaa taacttttcc tgtaaaaaca cgttctttgc gcaaaaagcg
    14941 gtaatcagtt acttgttcaa tacgattcaa ccaatcataa aacgttctgg aagaaagaga
    15001 aggattaatc attcgtattg ctgtagctac tctataataa caactctctg ccatttaact
    15061 tcacctcctt agttgattac aaaatatgcg catcagaaaa acttgttcct tttggatctt
    15121 ttgctaaata catttggcgc tctagttgtt cttgtaacaa ctgattatca tctcccatcg
    15181 tttgatcttg actatcctct tttactgtaa aatcatagac aatcatttca gtaaatttct
    15241 caaattcttt gataaagtga taatctttgt aaacaaatgg cgcaaaaaac tctacaggta
    15301 catcaaatcc tggaaaagca tatccacgac caggttgatc tttgttgtaa aatggcttat
    15361 ttttaaaatc ttctccaaaa gtcattaaat aaccaatggg agacaatcga ccaacagaaa
    15421 tacggaatgt taaattatcc cgaacaccac ttggaaaata ttctgcatct ggtcgttgca
    15481 ttgctaaaat aatgtacatc cctgcttgac gaccctttaa tactaatggc tgaatcaatt
    15541 tatcgactct atttctcgct tccatatcca acgaaccata aaaagctgcc cattcatcaa
    15601 aaaagataaa atgcggtggt aacccataat aagcataatt tttccctggt tcatatttag
    15661 gatctttcat ggttttcata taggcatacc gttgattcat ttcttttaat gcatttcgta
    15721 aacaaataat catttcttca tttattttgt aaaacacatg tcctttgaat acatcgacgt
    15781 cacctaatgc tgctaaatct gccgcttttc catcgcaaat atctactgtc ccaacactta
    15841 aacaagcttg aattaaagaa tacaataaat aggttttccc accaccgatt gcaccagcaa
    15901 tcaacatatt tggtgattga tcatataccc aatccaaagt tttcattaaa tgaatacgtc
    15961 cattttctgc tatacattga tcaataggaa tccgaccaga atctgaaagg aatacataat
    16021 tgattcgggc tttttctcgt tcttcacgaa ttaaatcacg caaaaatact tcagataaca
    16081 aatgacccat ttttaaaaat cgttcgtgaa aacgcccacc atctaaagga aaagaaacca
    16141 ctaattcttg tttcttttga taaaaataaa cttttggtaa tctcattttt tcccttgttt
    16201 gtttctcact aacttgtttc tttgtataaa caaaccgatt gtcaattaac attcgaacaa
    16261 gtaactgacg ccaataaaca gaggcaaaat atccttcttt tagtcgcgac caatgcatca
    16321 accctaaaat taacccacta accagcaaca aatacaacac aatacttatt ccaggaataa
    16381 gatacatttg ccaattcgaa aacgtactta aacgtggata aaatactttc caactaaacc
    16441 aacctaacag aatcaaaaat ggaaacaaaa agaaaccata atagcaaaac cataaataac
    16501 gattgaaata gcgaattcgc cgaccacgat acttgaaaaa atgagctttc aattgtcaca
    16561 ttcctccttt ctgtttttac ttttcctgtg ctaaaaactt ttgacaaaaa gcaactaata
    16621 caggaatatc acatttagta aaaaaacata atcgaaaaag atttaatcga tttttataag
    16681 ggtgtgcaca catattacat attcgtacta tacgaatcca aatcacttcc tgatgatctt
    16741 gtttccactg gtacggtaat gaaaaacgaa caagatcacg taaaaacata cactgcccaa
    16801 taaccgcaca aatatatgca tttgtttgta caaaaatcgt tggattgtct ccaaaatact
    16861 caatcaattg ttggatattt tgataacaag cacaatctct caaagtattt gattggtttt
    16921 atctgaattc aaaatctccc cttccttcta tcttagataa aaagaatagg aagactcctt
    16981 cctattcttt caaaaaaacc ttattttttc tctttttcct tagaatcaac acttggttgt
    17041 ttttgatcta aacctttttc ttgtgattgt ttcatattag gattatttgt tggagcttct
    17101 actttctcta atcctttcgc ataaatcact aaatctgaat attcacgatt gccatcttgt
    17161 gctggaatat ataccacatg atattctgga tcaattaatt tcacaggatc acgtcgttta
    17221 aaaccagtca aatctacatc tgctggaaat ttaactcgtc gtgcaatctt tggttcatct
    17281 ggatttccaa aaactaattg tgctcgctgt gatcgaattt ctcccgtata atcgcctgtt
    17341 tcattatcaa atacacgatc agactcttct aatgcgccaa agcgtacggc tcctaaacaa
    17401 gtttcatcta atgcttctgt aatgtcataa ttatttggaa attttaatcc catcttacaa
    17461 aacctcccca atttttacac cagttaaaaa gacaccaaca tcttgatagc cagttgttcg
    17521 acgctctgtt tgtcccatat catttgtttc acgactattc actcgttctt tacgaaaaac
    17581 aaaataagct tcttcaaatg aaatacgcac ctctttttct ggtaatcgta atcttttatc
    17641 ctcttcagct gtgagataaa caaaaaaagc aggctgttct tctcgcgaac actctgcttg
    17701 taattgaaca tatcgcccag acacaccatt aatttccttt ggtggattag gttcccgtga
    17761 acccaataaa aatacttgac ctaaaaactc tttcttcata cgcaatgctt tttctgccat
    17821 aaagtttttc ctcctcttaa aaaccaaaat aaattctaaa tatttctaca ttacaatcaa
    17881 acaagcggtt aaaaatccta accgcttgtt cctcatgact aatctttggc tttacgtact
    17941 ttataaagtg ttatacctaa agcaatgact aatactacta atccaagaac cataagtata
    18001 ctacttgttt gttcacctgt ttttggcaac attggtacaa cagtagctgg tttaacccgt
    18061 tgttctggtt tcactggttg cggtggtttt ggcgcttcca caatttgaac cgtttgatct
    18121 ttgtttgtta gatctacatt gtgtttcgcc acttcttcaa acgtttcttt ctcatcttcc
    18181 gttttcgctt ggagccattc cgcaaaactc aagccttttc ctgcaagatt gcgaccgtcc
    18241 actaagaatt caaataagaa ttccatcatt tctttatcgg ccgcaaagac tttttccgca
    18301 tgagtgcctt caaatggtgt gccgtctggt gttaagtagc cttgaacaat taagcgatag
    18361 atttgaccaa tcgcaagacc gtctactttg acccattcaa gcacagtttg atttggcaag
    18421 gccaagatct cttttccgcc atttttattc gtcgctttcg tcgtaatggt tggattactg
    18481 attttgatgg tttggtcatt gtcggtaata tctgcgtgag aagccaataa tacgccttct
    18541 ctaaacagat cttcaaagac cacgacttct ttgcctcgca acgcacgtgc gtctagaata
    18601 aagtctagat tgactgtacc atccgttgtt tctgccacaa acgttaaggt acttgtgact
    18661 tcttttccat ctactagcac tggtttttcc gttactttgt ccattagaac accgttgact
    18721 gtgtatgttt ttccaacgac caaatcgtgg tatttcacag cgtctgtaat ggtgactttc
    18781 gttaatggat taacctcttt caagccagtg ggtttatgtg tagccgttgt acgtacactt
    18841 gggttagtta ctcgtaccgt ttgccctttg tcgttgatgt ctttatggtt tgctagttct
    18901 tcatcatttc taaaaagact ttcaaacacg acgatttcac gaccatttat acctgtcaaa
    18961 tcaaaggtaa atggtacgat caccgtttca ttttctgctt tggcaataaa gccaacactc
    19021 gtttctaccg tatttccatg cacaagcaag ggttcaccgg ttgctttatc cattaagatc
    19081 cctttgacca agtatgcttt tcctggaaga atctcggtaa tttcaacggt atcgtttaag
    19141 gtaaacaatc ctgttgggtc tgcgactgtc aatccgtctt caaagacagc cgtggtatga
    19201 acggttggat tattcacttt cacactttgg gcttcatcgt tgatatccgc atgtgctgca
    19261 acttcaatgc catcacggaa aagtttttca aaaacaacga tcgtttgacc tttcagaaca
    19321 ctagcattaa ccacaaattc aaggtctttt gtgccattga ctttgtctgc aataaaggcc
    19381 aaggtacttg tgatttcttt gccatcttgt aaaattggcg cattcgttgc cttgttcatc
    19441 aatactcctg aaatggtgta ttcttttccg acaaacaagt tggtataaga aacactgtct
    19501 ttaatgacga tcgtttctaa tggatcaacc actttttcac catcggcttt atttgacgct
    19561 tgtgtttcta gttttggtgg aatcaagtaa ttacgtacag aaaccactaa cgtttcccca
    19621 tcatctggcg cattttgttt gaatgcaacc gtgaatgctt gtttatctgt atttggttgg
    19681 aaactttcta atggggcatt ttccaagaag taatagtcat cggcaactag acctttcact
    19741 aaaatttccc cgttttgatc agtggtatat tcaccaattg cttgattttt accgttatac
    19801 aaggtaaagt tcacacctgc gagcggcgtt ttcttcttgt tccattcttc atacttgaat
    19861 aattttacac ttttccgtgc ttgacggttc gcaaaatgga tcactttgat cggttctgta
    19921 tcattggtaa tcgagaacac taatgggttt tgattcaaaa cgtaatttac gggggctttg
    19981 atttcttcca aacgatagcg atcttttcca taagtaagtg taccgttagt taggaaaaag
    20041 cctttttcat tggttttaaa gatatccgtt gtttctgtat catttggaat ctccattgtg
    20101 acataacgat tggctaaagt atcaaaaatc ttgaattctg tattagcaag tggaatcact
    20161 tttcctgttt cttgatccac tttcaccact ttaagacgtt gttcaattac tttatcttct
    20221 aaaacataat ggaaagtttg cccattttca gaaattgtga cttcaagtgg ttcaaatagt
    20281 ttataccctt cttttccttt ggtttcagaa agaatgtacg tatcaaagac aacggtattt
    20341 ttaccaaaag tagcataacc atcattgtct gtcacaacgg ttttcaccac tttgccagtt
    20401 gtttttgacg tcaaagtgat ttcaatgcca gctaattttg gtttgttatc tggattcgtt
    20461 gaatcgacta aatctttatt agcaactttc actaaatcaa tggttccttt gatcacttga
    20521 tcttttgcgg tcgcattgac agtttttcca ggttcaacaa caatttcaat tgcttcatca
    20581 gaaagcacat aaccttttgg cgctttgatt tcttttaaaa catatttgcc aggatcaaga
    20641 tctttaattt ctgcctgtac tttgccgtta atttttttca aggtaatttc tttaatcttt
    20701 ttcccatctg cttgatacaa accatagacc gcattttcta aagaagctgc accttgtgct
    20761 ttcacaccag tttccgcatc ttctttaaac acacgaatgt ttccttgttt tagaatttgt
    20821 aaattaataa cagacgcatt aggttctgtt ggatgtaaca caccaattgt ttgagctcct
    20881 ggacgacgat aggctaatgg cgcaccttga actttaattt tattcaattg aatttttgct
    20941 ttatccggtg cctcttttgt gactgtaatc catacttcat tgccgtgaat agatacattg
    21001 acaccttttg gtttttgaat gtctttcaca tatttcaaaa aatcattttt attctttact
    21061 ttcaacgttt cgccaatttt taccgtatgt gtttgattat taaaagttgc tttttcacca
    21121 aagttattaa tcaaacgttg aatttctgct tttcgacgat cataatcaac acggatattt
    21181 ttgattggga tttttgtgcc caaagcttcc caaatcataa attgtgccgc aatgtattgt
    21241 tcatcggatt tgtctttatt tgtgacatat cctaaataag agatcaagct tgtttttttc
    21301 cgtacatttg aatttttcaa atagtttttc aaagcagtag ctgtataaac ttgaccttct
    21361 gcggctgaga caccaggctc aatacaaaac gccacttgtc cattaatctc aaaacgaacc
    21421 atataattta aagtgaagtt tagattgttc ggactagaag taacaccaat attttcgccc
    21481 caatcaattt tccgaccacc taaaacagct gcattggttg cacggcgaac acgaaccgaa
    21541 cgattggttg gtactgttac taacagtgta ggtgtacctg tttttggaat gttctgctct
    21601 tttttctttt gattttcaat actagccgta gattctttgt ttggtttcgt tggttgattt
    21661 tgactagctg cggttgaaga gattgttttt tcaacgtttt cctcattttt tccttctttg
    21721 tcagcagtag ccgctggttg ttccactgtt tcttctattc gtttcttttc ttccgcttgt
    21781 ttctcagaag actctggctg cacagaaggc gttgcttcgg cagctttttc tccttctaga
    21841 gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt cttcaactgg ttgtgaagta
    21901 ccaggactat tccctgggtg ttgtgtttcc ccaatcgtct gatcgagagt cgttttggaa
    21961 ttgaccgttg gcgcttctgt cacaggggcc tgttcaacag tggcttcacc agctgggacc
    22021 ccggcttctg ctggttggac ttctgtcact tcagaagcga cttgggcaat ggcttccatc
    22081 gtaggttgta tagccgtcgt ttcttctgca tgtgcttgag cagttcccac caagaaacag
    22141 aattgagaaa aagccaccaa tgcgagtgct ttcaaccaat tcattttcgt ttttgcatac
    22201 acaagaattc ctccttttcc tgagaatttt atataataaa acaaaacgcc gttaccaaaa
    22261 gtgataacga cgtgaactgt ctcttctatt tttatctggc gctcttatct gaacacattt
    22321 catcaatgat tttaccctcc cactataatt acagaacaaa aaaagaacct gcttcgtgga
    22381 aatcaactgt ccatttccca attggaatac cagctttttt ggcaacttca ccatcaccaa
    22441 atctcatgcc ataccaatta ctaccttcat ccttaatttc tttccaacca tatgacatag
    22501 cttcatctaa tgaatcaaaa atcatgacac tattgccaat tgttacagga tctggcttaa
    22561 gatcttctgg aagagaaata tcaatcatac cataatgatc cgattcctca gtattattgt
    22621 cattactagc tactggtttg gttgttctac tggcttattt tgatacaaca agtactctta
    22681 ttcttctttt acttctccgt tttcaatttc ccattcaaac cactccgcaa agtcttgctt
    22741 aaaaccatct actcgatacc tattttgtaa ataggcatct tctgacgtcg taggatctaa
    22801 ataggtaggt ttattctctg gacgagcata gacacctacc catgtttcgt aatctccttc
    22861 aaaataacta tctaccaaat agcctttttt tctaagaatc tcccgaactt gatttttaat
    22921 tattgatact tgttcaaaac catcactcat tctatcacct caaataactc tagattctca
    22981 taaatattcc cgacaatttc aatcctatca atgatctcta acaaatcgct acttatgctt
    23041 ccccattcgt ataagaattt cccttccgca aaataaattt tccataaact tcttcatgat
    23101 cgtcccaacc aatatcactc tcgaaaaatt ccacgttgtt cttatctttt agctcagtaa
    23161 atgccataag ttcaacatgt tttccaacct cgaaacaatc acaccaccca tcaaccgtta
    23221 cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt attaaacact aaaactttcc
    23281 gcattttttg ctcattaatt aatcacgcgc gaaatctagg aatcacaact tattcgcttc
    23341 ttctttataa ataaaaaaac tccaataatc ggaaattact atcttttcct cattcctttt
    23401 ttaaatcttc atacttcttc ttatctttgt cctaacctaa taacacaaat tttgaagaaa
    23461 aactcagtaa aacctgattc tttttttatc ttcacaacaa ccaacttttt cttcagatcc
    23521 ttttactaga acttgtatac aaaaattgtt gaatgctgat ataatttgcg gctacttgaa
    23581 aaaacgatag atgtaaaaag ataaatagaa tcatttttta ttctatatca gtctatgatt
    23641 cattgcttat caatcaccca acccattcga tgccgttttt tttagagaaa tttaaaaaag
    23701 accgtacgaa tctcgcatta tccgattact tttccagaaa agatccccaa ttctgtataa
    23761 ataaccctat cttcttgttg gtttcatttt ctcatataag aattcagtca atctacccac
    23821 tatgaccatt actacgtcca acacaactga catattaacc acgtaagtat tccctcacag
    23881 atctccgaat ctccatggta tggattccca tcctgacgct gcagaggaca acatatttca
    23941 tgtggctctg tacccttttg atttggaaac actacaaatc aatactcatc tataacttat
    24001 caagcgaact ttcgctaggc ttctagtgat tactaaattg ttggataaca tacatagccc
    24061 attttatcta gctgttattc ataacagtta gttcttgtat tacttcttcc gcttgtgttg
    24121 ccattgagct tgtcaaaaag ttacttagaa aaaagctgcc agtaaagcaa ctttcaacaa
    24181 accctttttg tttcttatca tatcaagaaa
//
LOCUS       DAMEEU010000045        23961 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.046, whole genome shotgun sequence.
ACCESSION   DAMEEU010000045 DAMEEU010000000
VERSION     DAMEEU010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23961
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.046"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            144..542
                     /locus_tag="PB779_001735"
     CDS             144..542
                     /locus_tag="PB779_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDE0739257.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            526..1221
                     /locus_tag="PB779_001736"
     CDS             526..1221
                     /locus_tag="PB779_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HDE0739258.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1815..2702)
                     /locus_tag="PB779_001737"
     CDS             complement(1815..2702)
                     /locus_tag="PB779_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDE0739259.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEGAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2887..3726
                     /locus_tag="PB779_001738"
     CDS             2887..3726
                     /locus_tag="PB779_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDE0739260.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNRTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3922..4896
                     /gene="sgrA"
                     /locus_tag="PB779_001739"
     CDS             3922..4896
                     /gene="sgrA"
                     /locus_tag="PB779_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HDE0739261.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5194..5550
                     /locus_tag="PB779_001740"
     CDS             5194..5550
                     /locus_tag="PB779_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739262.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5553..6710
                     /locus_tag="PB779_001741"
     CDS             5553..6710
                     /locus_tag="PB779_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739263.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6736..7176)
                     /locus_tag="PB779_001742"
     CDS             complement(6736..7176)
                     /locus_tag="PB779_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDE0739264.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7336..7842
                     /locus_tag="PB779_001743"
     CDS             7336..7842
                     /locus_tag="PB779_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDE0739265.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            8010..9923
                     /locus_tag="PB779_001744"
     CDS             8010..9923
                     /locus_tag="PB779_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HDE0739266.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9928..10929
                     /locus_tag="PB779_001745"
     CDS             9928..10929
                     /locus_tag="PB779_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0739267.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(11131..11337)
                     /locus_tag="PB779_001746"
     CDS             complement(11131..11337)
                     /locus_tag="PB779_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HDE0739268.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11983..12831)
                     /locus_tag="PB779_001747"
     CDS             complement(11983..12831)
                     /locus_tag="PB779_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDE0739269.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12830..13897
                     /gene="gnd"
                     /locus_tag="PB779_001748"
     CDS             12830..13897
                     /gene="gnd"
                     /locus_tag="PB779_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HDE0739270.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKRTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13899..14900
                     /locus_tag="PB779_001749"
     CDS             13899..14900
                     /locus_tag="PB779_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HDE0739271.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14897..15181
                     /locus_tag="PB779_001750"
     CDS             14897..15181
                     /locus_tag="PB779_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HDE0739272.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15214..16011
                     /locus_tag="PB779_001751"
     CDS             15214..16011
                     /locus_tag="PB779_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDE0739273.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            16025..16858
                     /locus_tag="PB779_001752"
     CDS             16025..16858
                     /locus_tag="PB779_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739274.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16876..17733
                     /locus_tag="PB779_001753"
     CDS             16876..17733
                     /locus_tag="PB779_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDE0739275.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17755..18264
                     /locus_tag="PB779_001754"
     CDS             17755..18264
                     /locus_tag="PB779_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739276.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18301..18702
                     /locus_tag="PB779_001755"
     CDS             18301..18702
                     /locus_tag="PB779_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739277.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18814..19167
                     /locus_tag="PB779_001756"
     CDS             18814..19167
                     /locus_tag="PB779_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739278.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19201..19644
                     /locus_tag="PB779_001757"
     CDS             19201..19644
                     /locus_tag="PB779_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDE0739279.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19661..20746
                     /gene="uxuA"
                     /locus_tag="PB779_001758"
     CDS             19661..20746
                     /gene="uxuA"
                     /locus_tag="PB779_001758"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDE0739280.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20739..21452
                     /locus_tag="PB779_001759"
     CDS             20739..21452
                     /locus_tag="PB779_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDE0739281.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
     gene            complement(21659..21808)
                     /locus_tag="PB779_001760"
     CDS             complement(21659..21808)
                     /locus_tag="PB779_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739282.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            22204..22404
                     /locus_tag="PB779_001761"
     CDS             22204..22404
                     /locus_tag="PB779_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDE0739283.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            complement(22508..23809)
                     /locus_tag="PB779_001762"
     CDS             complement(22508..23809)
                     /locus_tag="PB779_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDE0739284.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT         8181 a         3725 c         4947 g         7108 t
ORIGIN      
        1 tccatacatc cattgtactc tgagaaatca cacaatatcg aaacaaattc cgttaggaat
       61 gtgttattca ataaatttta taatctagaa acattttgaa taaaaactat tagacaaatg
      121 atattttacg aggaggaaca gagatgacga tctttgaaac ggttgtaaca gatgttggta
      181 tagaagcaga agtattcagg aaagaaaaaa taatgatttt atttggagat gaagcaccgg
      241 aaacattaac agattattgt tataagattg aattgaatca ggtaagaaaa gaaataactt
      301 gtgatatgaa gctctgtttt gataaacaaa tgtatgtaat cacagcagta ggagatgttg
      361 tccaaactaa tttgaatgaa ttaggacata tcacgataaa atttgatgga tctcatgagc
      421 cggaacttcc aggaacaatg tatgtagaag ataaggaaat gccgcattta agaaagggga
      481 caatcattaa aatcgatcaa gaggatcaga atgggggaaa gctatatgga aatcatgctt
      541 gatacagcaa atacaaaaag tatttattct tgtcaacagt ttttgaattt aacaggcgta
      601 acaacaaatc ctacaattct gaaaaaagaa ggagcgtcaa acttcttctc gcatatgaaa
      661 gaaatcaaaa aaataatcgg acagattcct atccatattc agacaatagg aagaacggaa
      721 gaagaaatga tagaggatgc tcgagttatc atagaagaac tgggaaaaga tacgtttatc
      781 aaggtgccgg tgaatcaagc aggccttcaa gcgatcaaaa agttgaaaaa agaaggttat
      841 ttgattaccg gtacagctat ttacacagaa ttacaagggt atttagctat taataatgga
      901 gcagattata ttgcacctta ttataacagg atgcaaaatc aaggcattga tgctatgaaa
      961 gtgattgatt cgttgcggac tgagatcgaa cgtacgcaaa gaccaacaaa aatattagca
     1021 gctagtttca aaaattgtga acaagtcact acagccattc gatctggagc tcatgcgata
     1081 acgttaggta aagagctact agatcaagta ttagagatgc cctcgattga taaagcagtg
     1141 aggggcttcc aagaagattg ggtgcaaact ttccaagcag aaacgattgg tgaactaaaa
     1201 aaggtcgctg attacttctg aatcaatttc tccataaaat aaacgatagc cttctcgaaa
     1261 actcgaggag gctatctgac gattcaatat tcattaattt aaagtttggg tgactattac
     1321 taactattac ttatttctca tttaaacgat gtattcccta acctctaata catccttgta
     1381 actctgaagt tacgccagtt ttgaataaat ttcataaaaa caaatgaaaa gtgtcgcata
     1441 aaaatatctt tcgtgtttct ctagtataac agaataagaa gaacaagtcc agaagggata
     1501 tttttagtct tttttaaaat aacttttcag tcgagtttga gtttatgata gttgtttttg
     1561 aagcgatacg gcaagtgaaa aaatagggaa gcatgaaaga atctacttaa tggcgcattg
     1621 attcatgtga tagaaataaa aaactttttt aaattatatc ctcatgattg taacaaatcc
     1681 agtgatttgt tttggtacaa ataaaaaaag gccccgatga agttgtggca aaagtggttt
     1741 gcctcaaaaa taagaaggaa tttccaaaaa tcacttctca aattttgcca catccccaat
     1801 tgggtcaaat ttgtttattt gaatatattt tttacataag gatctttaat agttacattg
     1861 tcttttttca tcactttacg gattgtttta tccatgaatt ccgtatcaag agtttttgct
     1921 tcggtagcaa ttttttctag ctcagatttg tatttgtctt tattagaacc tttatcctgt
     1981 ttttttacca tttttactag ataatagctt tgctgataag tcgttggatc tgttacagga
     2041 atgatatcag aaacttcccc gttttttagt ttaaatgctg ctttttttac ttcagtagga
     2101 atctctggat tggttgaatc aaaattcatt tttccatcag tttcctttaa tgttttattt
     2161 tttccataag cttgaacaag cttggagaaa ttttctcctt catttgcttc tttttttgct
     2221 ttatctgctc cttctttagt cgaaaataga atgatctgtg tactaacttc tggatagaat
     2281 tctttccaag cagtgtctag atctttatct gttaatttta cattggcttt caaaccgtat
     2341 tggaaagcca gcatctgttt aaagagtttc ttatatgtct cttctgtttg gccaactgct
     2401 tttaattgtt ccttgtagtt tggaccgagt tttttgattt gttcattata ttcttttgtt
     2461 acttcctttg aagaaatctc ttttccgtat acatcatcaa atgctttgaa gacaatcatt
     2521 ttttttaata gtgtttgatt atttgattta acttttgggt tatcataaaa atcctgaact
     2581 gtaagtgttc cacctttaaa cgttgcaatc gtttcattgg acttgctaca acctgagaat
     2641 agtaaaattg cacatgctga aaggcacata attagtagtt gttttttcaa aaaatttccc
     2701 atcctttcct tattaaaaac agtctaacag aagaattagg gagacagtct ttcattttcg
     2761 taaggttgct gtagatattc ttagttcgta aaaatctatt ctctctatga tggagaacat
     2821 ttacatagtt ttcacgagac aagaaagaaa agggttgtta aacttaatat aaaggaggga
     2881 tgaaagatga tcaggattat tcggttgatt ggatctgttt taatagtctt agttggtttt
     2941 gttttaggaa ttcttgtcaa taatgcactt gcggatatgt ttattggaaa tagtgaatgg
     3001 attggagcaa ttgccggtac ggtcggacat ttagctgttt ttttactagc tttatttctt
     3061 gctagtaagg tcgaaggaaa aagaatagaa gattatggtg tttctgttcg aggaaaagac
     3121 tgggggtatt tagcgggagg tctcgttgtt ggaattggag tgtttctgct tattactagt
     3181 ccattatatt tgacgggggc gtatcggtta gattcaggaa acgcaaacat tgtgccgctg
     3241 ataacgagtt ttattttatt tattgcagtg ggggcatcag aagagctttt attccgtggc
     3301 ttttttcagc atcagatgct tagatttggt ccgttaatag caatgattgg atctgctgca
     3361 ttatttgctc ttttgcacgg attgaatcct aacatgacat ttctggcagt tttcaatatc
     3421 tttttagcag gttgcttttt cagcgcactt atctacagta caggaagttt atttacggct
     3481 attggtgctc atattacttg gaatcggaca caaggagcta ttttgggtat accagtcagc
     3541 ggaacgcaag aacaaggttt tttctccact ctgatccaat cgcaaaatac aataattact
     3601 gggggaaact ttggggctga agcatctata tcaactacat tattcttgtt agtcttgatt
     3661 gttggtttgt tactctatgc atataaaaca aagcggatga agaaatacac tgctgtttat
     3721 caataaaaga tgaagaaagc aaggctgata tcggtcttgc ttttttaagt ctgtcattga
     3781 ttaaacgaaa aagtaaacaa attcaagcga atacacgaca tcttttgtta gattttcaca
     3841 actgactgtc gtgttctcat cattttcatt ttatataatt cctttatcaa atagaaggta
     3901 attatatgga gagtgataga aatgaagaaa acagcgaccg tattatttgt tattcttggg
     3961 ctgagtataa ttgcagcaat gattggaatc agtacttctg caaatgaacg ggcaaatgag
     4021 aatctttcat ttactgtgaa aactgatcgg attgtttatg acatgacaca acaagtcatt
     4081 actattccag tcaaaccaaa caaaagcgtg aatgctagtg atgtacatgc tgttctaaca
     4141 tatggttggg atggtaatgg aagttcagaa aaagttattg gggaagttta tttaaaagac
     4201 gtacaatgga ccgctggtat tgagtataca ataatgattt ctgcagaact atcgattgat
     4261 gagatcaaga gtaaagataa agttgatttg attgtttttt atgatggaca gatgacgatc
     4321 acggagaatt tgaaaccaag cagttggaca gttgttggac cgccaagcag tacggatagc
     4381 acaagtagtg aaagcagtac agaaaacacg agcggtgaaa gcagtacaga gagtacgagc
     4441 agtgaaagta gcacagaaaa cacgagcagc gaaagcagta cggagagtac gagtagtgaa
     4501 agtagcacag gaagcacgag cagcgaaagc agtacggaga gtacgagtag tgaaagtagc
     4561 acaggaagca tgagtagtga gagtagcaca ggaagcacga gcagcgaaag cagcacagga
     4621 aaagtaaata atgaacttga tttggtacct atcataccaa ctaaggaaca aaagagaaat
     4681 gcagggagca acctaaaaag tgtgctaaaa cagcctgatt ttgtttctcg tggaattgat
     4741 catcaagaaa aagcgaaaga aacagataat agaaaaagcg atttaccaga aactggtagt
     4801 agaaccttga acaagctaat tacatggatg ggtgtgttac tcattttgat tgtaggagca
     4861 agctattttc gttctctctt ccatcgagtg aaataaagaa taaaagcaac agatctaaaa
     4921 ttgaataaaa cgatagattt ttgagtgaat atttcattcg agagtgctgt attgcctggc
     4981 gaagttgtag ctttgccaga tctatttttg tttactaaca tatttgagaa acaggaaata
     5041 acaggaacac aaatggaaaa taagagcaag aataattgac aatgcacact gcgcatggta
     5101 gtatctctga aaaatcagta acgaatctat ttgtacgtta ttcatgtagc tgtcggaata
     5161 agtctaaata atagataaaa aggagtatgt actttgtttg aagaatttat tgatatcaat
     5221 gaaaggcaag tatatcaatt tttgaactat tgttatgaaa gagacgagaa attatatgtg
     5281 gtgaaggata tcgctttaga tctaaactac accctggcta agatgaattc ggtgattcaa
     5341 caagcagaat cgttttgcga aaggtatcca gaatataaat tatcttttct ttcagaaaac
     5401 aagatgataa aagtcgagtt ttcttctcag tttttactga gtaaagttta ttctatactt
     5461 ttagagggaa cgattggtta tattttactg gattcacttt acaaaggtac ttatcaatcc
     5521 ttagaaaatc ttagtcaaaa aattatataa gtttgcgtac gattcaaaga aaattaagag
     5581 aacttaatac tattttgaaa aactatcatt tatcttgcag cttgaaaaaa ggtaatccga
     5641 tagaaggaga agaataccgt atccgatact tttttcactt gatgtattgg cagtcattcg
     5701 acgaaaatca ttctgatata ttatcaagta taaaaaataa acgtcaacta ttagaaaaat
     5761 ttgcgaaaca tgcgccatat acgcgtagta tagatagaaa gaaatggatc agcctactaa
     5821 gaatttcgtt gcaacgaatg aaacaaggcc actcgattac gtatgtccca gaagagatga
     5881 acaaatttgt gcatccattg ataacaaaag aagagtttac gcattacata ctagagcctt
     5941 tttttgaagc aaacttctgg tcgatgaatc acatcactcc aacagagcaa gcttaccttt
     6001 attttatgtt tggtgtaatg aacacctatt tggaagaaga tttgttggat actccagata
     6061 aagtacaaga aagttggggc tggattgaat cgtctattgt agaaaatttt gaaaaaaact
     6121 tcaagatttg ttttacaact tcagaaaaaa attatctata tgtcaatttg gcaatgatcc
     6181 atttgtattc aagggttttt gggacaaaaa agaaggtgga tgcttttgga aaatcagcag
     6241 aagacagaga ttttcagcat atatttccag tgatgtatcc aatcatgcaa cagtttttta
     6301 gtggggtagc tcgcagaatt ccagagctta atacttatta tgaaaagaac agacggttga
     6361 tttttcaata ctgtatgtta gtcagggata tttttataaa acacgaacaa cctgtcatat
     6421 tctatattca atcaaagtat ggtaaaacac aggaattatg ggcaaagaaa aggatattat
     6481 ctatgactga acgcccaata aaatatagtg catccgctga tcagttacct gatattgtca
     6541 ttagcgatta tcctatcgac aaaaaggcat atgatcaaac gaatacacag atattttact
     6601 ggaatggaca acctacaaaa aatgattggg cgcgtctgaa agctgaaatc ataaaaatca
     6661 ggaatgagaa aaatagatcc atattggaaa aattggattt cgttaattaa gaaaagcaga
     6721 ttgtttatgc caaaattaag acattgcaaa aagattattt tctttaaaat cgacaagatg
     6781 accagaaagc aagagttcgt tgagctcttg ctttctttta gttttagaaa ggaacatcct
     6841 gattttatct tcgctaaatc cagtcaaaag ttttgcagat tggtcgtaga taatcggttt
     6901 tttcaataaa gaaggggatg tacgaatctc aatatatagt tcactcaaac tgagttcatc
     6961 tattctgtga acaagatttt tataactaat agaatgagta gagagcattt cggtcacgcc
     7021 gttgtttgtc aattttagta agtggataaa ttcatttttg gttagtggtt gacgaattaa
     7081 gttctgttcg ataaacggta tatcatggac gataagccaa cgttttgcgc gtcttgaaga
     7141 cgagcagcca gaacctgtat acaatttaat catcatacat tcctccaata gctaagtatt
     7201 tatgaaataa taacatgaag aaatagtcga aaagtgccat ttagaggtgt aaaataagaa
     7261 aatgttgtca cgtataatgg aactagctag ataagaaata ctattaaatc aagaaaaaag
     7321 aaagaaggca caagtatgtc aaacacagcc gacgcaatag tagtgatcga tttacaaaaa
     7381 ggggtatgtt ttgattcttc gccgatacac gaattagaaa cagtgacagc attagtgaat
     7441 aaaagaatca aaacatacga aacgattggg aaaccagtta ttttcgttca acacgaagat
     7501 gctcaattag tgccacaaac aaaaccatgg gagctattgt cggaattatc tattcctgag
     7561 cacagttatt ttgtgagaaa aacccatgcg aattcatttt ataagactaa tttgagtgtt
     7621 ttattaactg aattggactg tcattcgatc gaattatgtg gggcacaagc agagtattgt
     7681 atagatacga ctgtgaagtt tgctcatgga ttaggatacc agcttatgat gtgtagagga
     7741 gcaacgacaa cttatgataa tccttttatg aaagcaaagg aaacaatcgc tttttacgag
     7801 aaaatttggg ataaacgatt tctgacattt ttggagcaat aagttgtttc ttcgtttaaa
     7861 aaaagcagaa tggatactgg tttatccatt ctgctttatt acgtaaaatg agaaaataat
     7921 cctgttctat ttttatggga taaaccattt attttttgta taaaaaatgt ttgcgtttac
     7981 atataattct cctagaaaca taaaaaggag tgaatagctt gagaacaaaa caagtattaa
     8041 agggagcgtt ggtcatctta tttgctgtaa gtacaagcgt cccgcaatgg acagtatatg
     8101 gagagagcat ttcttccgaa tcggaatctc gggaggtaga aaccacagaa actactgatg
     8161 ctggaaatga aacgaaatcg agtacttcac aaacagaaac aaatactgaa acaacggttg
     8221 agacatctgt tactagcaca gatcaagaaa cgaccgctac cacagataac caacaaacag
     8281 aagaagcaac agctacaaaa atgtcaaacg acgaatcctc ttctgctaaa gtaagtgaca
     8341 aagagaatgg gacagaaaat gatgatatcg gtaaaggtga aaatttcaat ggtaaagaat
     8401 atttgaatta cttcggtaaa cagatgacag aaatacttaa tggaccaaca gaagacatca
     8461 agtcaaaatt aatagagtta ttagtcactg agcttgctgt taatgattat ggtgtagata
     8521 aagagattat caaacatctg attgctactt atctattgta cgatatcgct tttgcaaaaa
     8581 acagtgtgtt gatgtcgatg cttggaggta cagatgatgg gacaacgcct acagaaaaca
     8641 caggcttcta tccaaataca aaacaacttc atcaaactgt actaaacaaa caagatggca
     8701 aaatgatgga tgtatatgca tattatgtcg atcaaggttc agataaaaca gtcatgatcc
     8761 atggcggatt tcgagggaat tggaataacg ggatcgttac agaagaatac aatgattttt
     8821 ataaggccgg gtataattta ttatttgttg attccagagc gactggtaat agcggaggcg
     8881 attatgtgac ctatggacaa tatgagtcag atgacgtcct ttactggata aatcaagaag
     8941 ttcgagagcg gccatctcaa aagattttac tttatggtgg ttcgatggga gcagctacga
     9001 tgatgtctgt attagcgaaa gatattcctg tcaatgtcaa aggaattatt gaaaattgcg
     9061 gatttgcatc aattgatgaa caactacgtt ttacgtacag ccagacagta gcccccgcac
     9121 taccggatgc cataaaaaat cagttagaca tcattgggga tcaagagcat gaagatttat
     9181 ttatgggcct tttgaaacaa tactattttg atcaggagat gcatttggat acaaaagctg
     9241 ctctacctac gattggaatg tcagattcat tgcctaaatt gattatccat ggaacagcag
     9301 atgatgtagt acctgtgtct aacgcgcaaa aattatatga gttatcagga gggtataaag
     9361 atcttttatt agtagaagga gcagggcatg gaaaggcaca ggaagttgac catgctgcct
     9421 acacgaaaca tgtaacggac tttttgaaag tagtgttcca tgatcagata aacgtaaagt
     9481 atgtggatga aaacaataaa agtctactca aagaccagga cgaaatccag ctttacggag
     9541 cttatggaga aaattatatg acagagcaaa agacattcga aggatacgaa ttagcaaatg
     9601 ttgaaggacc gactgaaggg atttttaatg agacgatacc aactattatt ttctattaca
     9661 aaaaaatccc agtagctcca ccaaaaaagc aagatccgac agagaatgca gacaataagg
     9721 gaaagaatga acctcgagag gatcaatcaa gtgatgatac gcaaccgatt cagatgacag
     9781 tgaaagtaca aaaaaagaca gatgcaaaaa aaagaatgtt gccgaaaact ggagaaaaga
     9841 aacattcgct tctcatttat tcaggtggat ttttatctgt tagcacgatt atcacatgga
     9901 tttggcgaag aaagagaggg taaatgaatg aaatggttca agcgaatagt gattgcagta
     9961 ccagttatca tcgtagttat tttagtcact gtatttttga ttaatcaaat cacaccaaag
    10021 ccgattagct tgcttgttag aaaacaattt gacacaagtg aaaaagaaca agtatatgcc
    10081 cgaccagatg atttccagca aaaaatcgaa caaatcgata taaaaaaaga aatatcctat
    10141 ccttcaaagt acaaaaataa taatatggat atctacacac cgaaagtgga aaagaaaaaa
    10201 ttaccgattc ttttctggat gcatggaggc gcatatgtag gaggggataa aaatgattgt
    10261 cgtgattatt tggaatatct atgttcagac acgcagcaaa tcatcgtaaa tatagattat
    10321 gaacgatcac cggaagcaaa acatcctaca ccagttatcc aattgaacga agccattcaa
    10381 gcagctaaaa aagagataaa agatcaagca gattggtcga atatttcgat tggtggaaat
    10441 tcggcaggtg cacaaattag tggagaatat ttgttagcac ttcaaaatga agaaattaaa
    10501 aaagctgatc atcttgatcc gactttggag aacaagcaga ttacgaagtt tatttctttg
    10561 tctggtctgt tggatccttc tgcacttact caagtaagtg ataaaatctc tagctttctt
    10621 tatgaaaaat gtggatgggc ttactttgat aataaggact ttgaacaatc agagaaggtc
    10681 aaaagtttag ccttggtcag acatgcggat cgttggacgc aaaacacatt cttaacggat
    10741 ggaaatacaa atacgtttac gaaacaaatg gaagaagtaa cttctgtatt tgagaaagcg
    10801 ggggtgaaag tcacaaaagt agattatgcg gagaaaaatg ctgttttgaa ccatgaatat
    10861 cagtttgatt tcagcaataa acaagcgcaa gaaacatatc aaaagttagt aatgtttttc
    10921 aaggagtaaa gtcttatgat gcaaaagagg ttgtaatctg tcacttagct ccaagtcaca
    10981 aggagcaatt tcaataaaca agcttttcat ggtttatgaa tattgtaact tgtgactgag
    11041 gagttagaga tggcaagggg caccttttat tcgaaatttg ggaatatcac acgattattg
    11101 tcacgatctc ttttacgtaa attttataag tcagatttgt tgttttgatc gtttaaaaaa
    11161 agcaacaaat ccgaagcctg cggaggcaag aagggacaaa aagccgagtg gtaagcaaaa
    11221 gaatgctggt tccactaata ttccgttgtt attgatataa ggctgggaac aaagatgaat
    11281 agcaaataaa atcaatgcac tagcgaaaaa aagcaaagaa atatggatag ctttcataag
    11341 cagcacctcc ttttttataa ttgtatgata aatagattaa gaatctataa atgtgacaag
    11401 tttgttagga tgtgaataaa atgatcatct agcgaacttg aaacaaagat ggctaatgat
    11461 aagcaattaa tgattcagca atcagatagg tacaaagttt accatcatac gtctagacca
    11521 ataatagaaa atatgggaat ataatagaaa agatttagga tacccccaaa agaatttccc
    11581 caaaaattcg atgtatccta aactttttta ttttacataa caatcatatc aactgtgaaa
    11641 taaaattaca aatgataacc taaaatgagg ccaaaagcca gtgttatcaa ggaaatactt
    11701 aattcaccaa aatttttttt aattttttag aaaataagaa acaaaaataa taaaaaaaag
    11761 aaaagataaa ttttttacta ctgtatacta actttgttat cgcatctaac aagtaactcg
    11821 aataatacca atacaacctt ctccaaagat gcgatgacat acgttctaac ccaccgacta
    11881 ttgatgttct gtaccaccct tgcagaacca aaaaagccac taccaaatat ttggtagtgg
    11941 ctttttttgt tttatggatt tttcgctttt tctgttatgg tgctattctt tgatttcaga
    12001 aatagtatgt cgaactttag cgatagaacg acgtgattct ttttcgttgt aaaacatcaa
    12061 aatcacatat agagagtcca aaatgcttag ttgagaaata cgggaagcta aagcttcaga
    12121 tcggaattct gtttcttcag aaatagaaat aaaaacgaca tcgccaagtt tagcaaggga
    12181 agaattagct tggctagtaa taacgattgt ttttgctcca gtttttctta cggtttcagc
    12241 aatatggatt gtttcttttg attgccctgt gtgagaaatc aaaacagcac agtctttttc
    12301 cgtcaataaa gaagcttcca tcaattgaat atggtaatcc gtgctgtgag aagttgcgat
    12361 aggggaacgc aaaaatttat gataagcgtc agttgctaca atctctgaac cgccaacacc
    12421 gaaaaaatag acacgtttag attcattgat aatagtagcc gcttttttta gatccttttg
    12481 ttgtaacaac ttttttgtgt catttaaagt tgaaatacta gactcgaaca ccttttgcgc
    12541 catagtgagc tcagtatctg ttttctgaat attttcgtgg atagaaatag cagatagatc
    12601 attttcttgg atcaacatgg ccattttaaa atctttaaat ccattataac caagtttttt
    12661 tgtaaattga aaaaaagtag agtcagcaat gcccagttca cttgctaaat tgctaatagg
    12721 actatgactt actttgcttg gattttctaa aatataatcg gcgatagcct gttcttttgg
    12781 gctgaagtcg ttgtacattg ttttgatttg tagtcttatg gagacgctca tgagaattcc
    12841 tcattttcat aataagatta tcattttttc cgttctcatt aatgttaaag atacaaggag
    12901 agtaggaaaa aatcaaacaa aaaatatttt tgtaaaatct atttacaaaa aaattttttt
    12961 gtataatgag ggtataagaa atggaggcgc tatcatggaa attggtgtaa ttggtttggg
    13021 aaaaatggga ttgaatttag ctttaaactt aaaagagcac catcacaaag tacaaggact
    13081 cgacatttca agtacagctg ttagtcaggc aagagaaaat gacattcctg cttatcaaga
    13141 gatctctgaa tttctagcta cttttgagca gaaaaaaatc atctggttaa tgcttcctgc
    13201 tggagagata accgaaaaca tgttaagaaa actttttcca aaactcggac caggagacat
    13261 tattattgaa ggcggaaact cttattataa agattcaatc cgtcgagcag aagagtttca
    13321 gaaaaatgaa atcggttact tggattgtgg gacttctgga ggaatcgaag gagcacgaca
    13381 tcaagcctgc ttaatgattg gaggagataa agaaactttt ctatccgtgg aacaattatt
    13441 caaagatgta gcaattgaaa gaggatatct gtatgctggt gcatccggaa gcggacactt
    13501 cttgaaaatg atccataatg gaatcgaata tggaatgatg caagcaatcg gtgaaggatt
    13561 ccaacttgta caaaaaagtg agtatgcttt tgacttggaa caagtcgcac gtgtttggaa
    13621 tcatggttcg gtgattcgcg gctggctgat ggaaatcatg gaagatcagt taaacgaaca
    13681 tcccaattta agtaattatc ggggaatcgt ttctgcatca ggtgaagcaa aacggacggt
    13741 tgaaacagcg ctagaaatgg ctgttccagt tccagtaatt gcaactagtt tgttcatgag
    13801 gaatctttca caggaagaag atagtttttc agcaaaagta gtttcagcac taagaaatgg
    13861 gtttggcgga catgaaatag ttgaaaaggg tgagtaaaat gccagattat catatagcaa
    13921 tcgttaattc cagcagtttc ggaagagtct ttccacacca cttggaaaga ttaaagtcag
    13981 ttggagacgt tcatttcttt actgttgatc aagagattcc aggaaaagaa ctagcggagt
    14041 tacttaaagg attcaatatc attattgcaa gtgttacgcc attttttcga cgagattttt
    14101 ttgaaaacaa agatgaactg ctattgattt cccgacatgg tattggttac aacaatattg
    14161 atttaaaagc agcaaaagaa caccagacaa tcgtatctat catacctgct ttagttgaac
    14221 gaaatgctgt agcagaaaat aatataacta atttgttgtc catgcttcga cgcacgacac
    14281 aagcacaagc aagagtcaag gacgatcgat gggaagatcg ggcggagttc gtcggtagga
    14341 cgctgtttaa caaaacagtt ggtgtgattg gtgcaggaaa taccggaagc ggagtaatcg
    14401 aaattttgcg taacggtttt cgctgtgatg ttctagctta tgatccttac aaatcagatt
    14461 tatacatcga aagctttggt gcaaaaaaag tagaacttca agaattactg gaacaatcag
    14521 atatcatttg tttatgtgcg aatttgacag aagagaacta tcacatgatt tctgataaag
    14581 aagtcgatca gatgaaagaa aatgtttatc tatctaatag tgcaagaggc gctctagttg
    14641 atgaagaagc gatgattaat ggtctgaaaa gcggaaagat cgcaggatat gccacagatg
    14701 ttttagaaga agaaccggga cgtcaagatc atccgtattt agcgtttgaa caagtagtga
    14761 ttacgccaca tatatcggcc tacacaaggg aatgtttaga agcaatgggt gaaaaatgtg
    14821 tcagagatgt cgaacagatc agtcagcacc ttcttcctga acgttctgtc cagacaaaga
    14881 gcaactatat aaaaggatga tgaagaaaat ggtgaacggt ttaaaagtga aaacaggccc
    14941 tcaattttat ttatatgaag aaggtggtat ttcaaaagtt tctgatctct tgaaatcata
    15001 cggcgcgaaa agagtactgg tcacccacgg aacggtatca tgggaaaagg cgctacctaa
    15061 attagtattt ttgaatgacg aaacgattca atttttttat catcgttatt ctggagaatg
    15121 tagttatgct gaagccagac gaatagctac aatcatcaaa aaaatgaaat cgatttcgta
    15181 gttggcgttg gcggaggaaa actgaccgat ctagtgggtt atagtgccaa tcttgcaaga
    15241 atcgatttcg gagtcatccc tactttagct agtaattgtg ctccatggac acctcttgct
    15301 gtcatgtata aggagaatgg acaagcagaa gggaaaacag aacactttta cagacaagct
    15361 gcttttttta taacagatcc ccaattagtg attgattccc ctgttccata tttcattgcc
    15421 gggttagcag atacactagc aaaatggtat gaatctgagc tcatcttaga acaagatttt
    15481 ttgcaagatg aatcattttt gaagctagca caagatactg cgaagatctg caaagaagag
    15541 attttgaatc attctgctaa agcaatccaa gatatggcac aaagaaaact gacatcggag
    15601 ttcaaacagc tttcagagat tatctttgct gttgctggtt tagttggagg attaggagat
    15661 aaatacgcaa gaaatgtggc agcacatgct atgcatgacg ctatcagtaa atatattccg
    15721 gaaagccatc gttttctaca tggagaaaaa gtagcgtatg ggattttcta tcaactggca
    15781 ctagaaggtc gctgggaaaa aatagacgag ttatatcctt tgtatcggga attagaactg
    15841 ccggtttctc tagaacaaat gggattattt ccgaaagata aacagataat agataaaatg
    15901 gctgaattta ttgattcgaa agagaaagtg catttgattc ctatagaggt aacacagaaa
    15961 tcactgatac agtcaatgat ggaactggaa ggttatatca gaaagatctg aaggaggagg
    16021 acacatggaa acattaagtg tagtacaaag tttgttgatt gctttatggg tagccgcggt
    16081 tatgtcccgc tggttaggtg gaggagccac gttgacctta cgtttttctc ctttgatgac
    16141 tggattagtc gtcgggttga tcatggggga agttgcacaa gcgatgattg ttacagccgc
    16201 tttgcaaatg atttatatgg gggttttttc tccaggagga tcaatgccag ctgaaccatc
    16261 tattgcagca gctatcgcag taccagtcgc attattaggg gatctgtcgc cagaagcagc
    16321 gattgccgtt gcggtgccag tcggattgct cggaagttac ttgtatcagt ttcgtttttt
    16381 catcaatact tttttaggta aatatacaga caaagctgta gaagatttga atacaaaagc
    16441 tatggcccga tcaattattc tttatccaac ggttgcctca tttttattat tcgttccgct
    16501 tgttttcatt gctttatatt taggggcgcc attgatcgct gatgtaatca aagctttaga
    16561 gggaacagtc gttatccaca ttcttgaagt agtaggtgga gggttagcgg caatcggtat
    16621 cgcgacaact gtatacgtta tcggtcgaaa agattatctg gtctttttct tccttgctta
    16681 ttttatgagt gttgttttga aatctttaga tattacgatg gttacttatg ccatttttgg
    16741 gattattatc gctttgatct ttgtccagtc gcaaaaaggg aaacaagtac agcctgccac
    16801 aagcaataac aattcagcat cttttgatga cgaagatgac tatgatgacg gattttaatt
    16861 taggaggaat gggaaatggc tgaaataatg gataatcaaa caggtgctcc tgaagaaatc
    16921 acgaaaaaag atgtaacaaa agcctatctg agatggcatt ttgcaaacga aattcctcac
    16981 tcttttgaac gttacttggc gccatcacta ctatacggaa tgatgccaat cttgaaaaaa
    17041 ctttataaag atgaagactc tttaaaagca gcatataaac ggcagttact gttcttcaac
    17101 actcaattaa gctggggtgg cggtgtgatt actggcctaa tgtcttctat ggaacagcaa
    17161 agagcagaag aagagtatga agaaaaagag atcttgatgc aggatgactt gatgtataac
    17221 acgaaagcgg gattgatggg ggcactagca ggaatcggag atgcaatcga ttcaggaacc
    17281 gtccaatata tttttatcgc aatcgcggta ccttgggcac aacagggaag tcctttaggc
    17341 gcactttttc cttttatctg ctttgggttg tatcaggttt tactaggggt atttttcgca
    17401 agacaagctt tcactatggg ccgtaatgct acaggcctaa agcaaaacac tggtgttcag
    17461 acagcgattg aaatgctatc agttttaggg ttgtttatga tgggggtgct tgcgggaaac
    17521 tatgtaaaag tagaatcttc attgaaattt gcgatatccg gacgtgagtt tgttatccag
    17581 gaaattcttg atcaaatcgt gccagggata ttacctttag ctgtcgtaat gggtgtgtac
    17641 ttgttctata cgaaaaaagg attgaaagtc acacaagcat tattatggct gactggaata
    17701 ttaattgtgc tagcaggaat cggtatttta taaaaagaag ggaacgtgaa taagatgggt
    17761 gtagtcaatt tagcgcgtgt ggatgagcgt ttgatccatg ggcaagtaat ggtaacgtta
    17821 tctcaaaaaa gtggagtgaa ttccattttt gttgtagacg aagttgtagc aaaagataaa
    17881 tttatgagag atctttacaa aaatgcagga agccgtacag gacaaaaaac aattgtcatt
    17941 acaccagaga aagctaaatt ctattgggat gaatatcaat ttaaagaata caattgtatt
    18001 ttgatcgcaa aaacagtcca aacgatttac gacttagtaa aacacggaat ccccatggaa
    18061 gaattgaata ttggagggat tgctcaaaaa aatcctgata cagatctttt agtgacgaaa
    18121 tctgtttatt taaataaatc agatgctgaa aaattgaaag aaatgaatga acaatatggc
    18181 gtaaagaata tttattttca agccactcca tctgcaccta aaacaggatt aaaagatgta
    18241 ttgaacaagt ttgatttgtc ataaacaaat gcttagaaaa aagataaaga gggcgaaaaa
    18301 atgaagaaga acgagctgtt tcgtgattgg gaatttcgtt atcgctatat ttaccgtaag
    18361 cgccgtacaa aaaagagtaa acagcgtttt ctttcagcat tagtatcaga tatttacagt
    18421 atgagaacag atgtgacagt cattgcttac gatacgctag cctaccgatc aaaaaatatt
    18481 tatgttggag atatcgaaaa agcagagaaa gttatctgta cttattacga tacacccgtt
    18541 catgcattag gaagttattt catgtttgat tggaaagacc aaaggaaaaa aacaatctac
    18601 tctatattat tgtccttcat tttgttgttc agtttaggtt ggtggggaat gatgatatat
    18661 aacaaaaatc ctcatcacgt attcgatctg ctatccgtat aaacaggtat cactgtacta
    18721 gcatttggga gctacttttt cttattggga aaagcagctc gcggatggcc tagcagacaa
    18781 acttttattc gaaatacttc atccatatta acgatgctag aaatgatccg tacgattgat
    18841 gatccgagtg tagcgtatgc gtttgttgat gaaggctgtt atggagaaaa gggcttagac
    18901 agcgtgagat cgggtatgaa aaaagaggct attctttttt atctagactc tgttggggca
    18961 gatacaccgc tacagttttc gggaaattat ttttcaaata aagaacagtg gctgaaacaa
    19021 gttgataagt tgaaagaaaa aaacgtcaat tatattttta gtgcaagaaa aaagcaagcg
    19081 cagttcttct atttgaccaa aacagattta cgagggaaaa catttaattg gcaaaatgcc
    19141 aatcagatta ttgctctttt tcgataagta aaaagtgcaa aacaaggagt gagaagacta
    19201 atgttggaaa tcatgatcgt tacacatggt aagttgagcg aaggactgaa agatgcggcg
    19261 gaagtaattg tcgggacatc gagccatatt gaaacaatgt gcttagagtc tggggaggac
    19321 atccaaacat tcggagagaa ggtcaaagaa aaattaacta tgatcaacac agcagaaccc
    19381 atgctagtat ttgttgatct aattagcgca agtccgtaca atcaagcgct cttggcagtc
    19441 aatgaactga ctgaagaaaa gaaagcagcc acttatgtca tagggggcgt gaatctgcca
    19501 atgttgttag aagcaatcaa tcatcagatg cttcacacac cgatagaaga agcggtggaa
    19561 caaattgtca aacaaggaaa agataattta actgtttggc atgcttcagc ggaagaaaaa
    19621 aaattagatg aggacgattt ttagaaggaa ggctgaaaag atgaagtggg gatttagatg
    19681 gtatggtgaa aaaggggatt cgatcccatt aaaatatgtt cgccaaatac cgggaataaa
    19741 tgggataatt ggaactttgc tgactaaaat gcctggagat gtttgggaga tttcagaaat
    19801 tgaggagttg aaagcatctg ttgagagcca aggactggaa ctgcttggaa ttgaaagtgt
    19861 agcgatccac gatgcaatca aggcagggac agatgaacga gattactata ttgataacta
    19921 tatacgaaca atcaaaaact tgtctcgatg tggggttcga ttgatttgtt atagcttcaa
    19981 accaattttt ggatgggcga aaactgattt gtttaatgaa aacaacgatg gaagctattc
    20041 tcttttatac gatcagaaaa tcgtcgatca gatggagcca ggagaaatgt atcaattgat
    20101 acacagccag tcaaagggat tcaaattgcc gggttgggaa gaagaacggt tgaaaaaatt
    20161 cgctcagctg gaaaaactgt atgaaggaat gaccgaagaa gaattatttg aaaatctgac
    20221 ttatttttta gaaaaagtga ttccagtgtg cgaaaaagca gatgtaaaaa tggctatcca
    20281 tccagatgat ccgccatggg aactttttgg ttttcctaga gtgacgaaaa atcttggcga
    20341 cttgaagaaa attctaaatg cagtagattc tccatataat ggactaacgc tgtgcacagg
    20401 atctttaggg gcaaatccgg aaaacgattt agttgaaatc atccatgagg taggttcgcg
    20461 catccatttt gtccacttca gaaacgtgga gtttttagga gaaagaaagt tcaaagaaac
    20521 ggcacatccc tctacagaag gctcccttga tatgtatcat attatgaaag cgttggtgca
    20581 agaagggttc gacggtccta tacgccctga tcatggtaga accgtgtggg gtgaagtggc
    20641 tatgcctgga tatggcctgt atgatcgtgc aatgggactc acttacatgc aaggtctata
    20701 tgaggcgata agtaaggaaa aaccactggg agagcattat gaataaaatc aagctcttca
    20761 tctttgatat ggatggcctt ttattagaaa ctggacgttt agcttatcgt gcttatgtaa
    20821 aatcagcaca aaagtatgat tatgaaatgc gtaaggaagt ctattattta ctaactggcc
    20881 aaacagaaat ggcgataaga gaacaaatgg gcattttgta cggagaagat gttccatata
    20941 tcaaatggcg agaagcaatc aatcaatata aagaaaaaat cgtgaaagaa gataagagag
    21001 tatatacgaa aaaaggagca gaagaaattt tatcttttgc aaaagaaaga ggaatccata
    21061 caatcgtggc ttcgtctaat acacgggtaa aagtagaaat gtatttaaaa atggaaaatc
    21121 tatatgcctt gtttgatcaa atcatttcag gggatgatgt aaaaaaagga aagccggaac
    21181 cagagatctt tttgaaagct tgttcaaaaa tgaatattcc tccaagtgaa gcacttgtat
    21241 ttgaagactc gattgcaggg atcgaagcag caaggcgagc gggcattttg tcttttctca
    21301 tcaaagatca tttgataggg ttgcccgatc ataatgggaa gcataagttg aaagtagatg
    21361 taagtttata tgaatccaat aaagcagact atgaatttta tgacctgcat caagcaaaac
    21421 gatttttaga aagtaaaggg ttgtatctct aataaagagg actattttct agtcctcttt
    21481 atttattgtc ctgcacgact gagggaacag atgaaaaaga agtaattttt tattttgaag
    21541 tatctacctt atttgtagtg aacaatttag aacaaacaca aaacgcatct actgttatct
    21601 accagtagat gcgtttaaag agaagaacga gaatcgtcca tatgagggtt tccactcctt
    21661 atgcagattt ttttaattct tgcactgctt gttcgatcgt aacacctgtc gctacatgat
    21721 tggtattttc tttgtcaaaa acgacaaata gattcaaatc tgtatccaag gttactcgat
    21781 attgtatatc tttgttatag aatgtcatag ccattctcct ttctttaaat acttgctgaa
    21841 aggcaacgaa cgcgttgata acgaaattcc atttataagt ataccaccaa ttgaaaggtt
    21901 ttcatagtta agaaatttta aagtcaaaag ttgcagataa aagcaaataa acaagaaaac
    21961 aaaaagtgaa tcaatcgcgg ttattcaact ttttcttcga ttcgaagaca atagaagaca
    22021 atgaatttta tatttcattg cattatcctt gtgttattag aaaaagcatg atatattaaa
    22081 tgagtaatct attttgaaac gtaatttgag cgatatatct acatagataa aactcctttt
    22141 gcctatcaaa tatttattgc aacgaaaaaa cgtacattga tacgtatcag gaggaattta
    22201 tttatgaata acggtacagt aaaatggttc aacgcagaca aaggttttgg ctttatcact
    22261 ggtgaagatg gaaatgatgt atttgcacat ttttcagcta tccaaggtga cggcttcaaa
    22321 actttagaag aaggccaagc agtgtcttac gatgttgaag atggtcaacg tggccctcaa
    22381 gcaacaaaca ttgttaaagc ttaataaaaa ttgactttta accgtctttt cgaaagaaaa
    22441 gggctctttg tcaaatagga ctgatagagt gagataagaa catctaaggt agaattcctt
    22501 ttctacttta gatgtttttt gattcatagg taatcagatt atttagtaag aaaattctgg
    22561 tcttcatttt ccgaaagctt cgaaagccat aagcgactcg tttcaatgct ttgatgtggg
    22621 tatgcagatt ttctattttg gcatttgaat aaggcaattc gagggctaaa cgaatgccgg
    22681 attcatagtt tataaaagct ttttttatag aatgcagttc ttttggaacg gaattgggca
    22741 tcgttcttac aagtttaaag aaagtgtccg cctctttgtc gtgaaacgct tgaagaattt
    22801 cttgatagta aaaataggcg attcgtaatt cgtcagagat cgaaagcaga cgatccacca
    22861 cttcactttc ggtgagatac gcccaaccaa aattgcgcca tttggtccat ttgtcataaa
    22921 caagcttgtc ctgtcgtttg atcagaagcc gagacaacgc ctttaattgt cgataatatt
    22981 tggcttgtgt tggatcgttt cgatcaaagc ttttcatgat tcgtacgcga atatcctcaa
    23041 atttacgaat gagatgtttg acaatgtgaa aacgatccac aacgagtttt gcctttggaa
    23101 aacattcctt tatcagagag gcataagaaa cattcatgtc cgtcacgatg acctttacct
    23161 tcaatcgtgc gcgtcgttca aattgcataa aataagaaac gagagccttt ttcttccgtg
    23221 aaggaagaat atccagtaat tttccagtat cgccatccat acaagaaaag gagtagggac
    23281 cgacttgatt tttcagtgaa cgaaattcat ccattaataa acaacgcggt aaccaatttc
    23341 tttttacttt tgtcatgggg atcagagaag cgagtgtccg agaaacggtc gaccaagaaa
    23401 cgccgcaatg cttagcaatt gtcgtcattg cttgtttttc agttagctct tctaaaattt
    23461 tatagcgcac ttgtttagcg ataaagcagt ttctatcgac aatgtaggta ttcgccgtaa
    23521 aataggtgtg gcagccacga cagtggtagc gttgtttcgc taaagcaaga taagtcagtt
    23581 ggttcgcaca tttattaagt tgaatgagcg attttttctt tccgttctta acgatcatgc
    23641 cttcatgatt catctgttta cacaaaggac agcgacgaat ttctttactt aacgtcgcag
    23701 aaacaacaag actcttgata ttcttaatgc tcttcgattc cacatttgtg atgaaaatgt
    23761 ttttatcttt gattccaagt agtagtttga tatgatgaag atcaggcata cagaacgctc
    23821 ctttgattgt gttgtggtga ttcaattcta acggagcttc tgtatgtttt gttttttcat
    23881 gctcaaaagg gaccgataga atgattttct atcagtccta gaaattatag agccaagaaa
    23941 agacggtttt tttgtacgaa a
//
LOCUS       DAMEEU010000046        23829 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.047, whole genome shotgun sequence.
ACCESSION   DAMEEU010000046 DAMEEU010000000
VERSION     DAMEEU010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23829)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23829)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23829
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.047"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(54..788)
                     /locus_tag="PB779_001763"
     CDS             complement(54..788)
                     /locus_tag="PB779_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HDE0739285.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1115..1525
                     /locus_tag="PB779_001764"
     CDS             1115..1525
                     /locus_tag="PB779_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HDE0739286.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1518..2219
                     /locus_tag="PB779_001765"
     CDS             1518..2219
                     /locus_tag="PB779_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HDE0739287.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYNIGGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGI
                     VANCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIF
                     GSLIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILT
                     VLLLPLFFQPFAGLF"
     gene            2219..3805
                     /locus_tag="PB779_001766"
     CDS             2219..3805
                     /locus_tag="PB779_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739288.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            3824..4045
                     /locus_tag="PB779_001767"
     CDS             3824..4045
                     /locus_tag="PB779_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HDE0739289.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            4042..4803
                     /locus_tag="PB779_001768"
     CDS             4042..4803
                     /locus_tag="PB779_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HDE0739290.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            5183..5692
                     /locus_tag="PB779_001769"
     CDS             5183..5692
                     /locus_tag="PB779_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HDE0739291.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(5767..6306)
                     /locus_tag="PB779_001770"
     CDS             complement(5767..6306)
                     /locus_tag="PB779_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HDE0739292.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="PB779_001771"
     CDS             complement(6446..7057)
                     /gene="rpsD"
                     /locus_tag="PB779_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HDE0739293.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            7319..8170
                     /locus_tag="PB779_001772"
     CDS             7319..8170
                     /locus_tag="PB779_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HDE0739294.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            8198..8833
                     /locus_tag="PB779_001773"
     CDS             8198..8833
                     /locus_tag="PB779_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HDE0739295.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            8853..9626
                     /locus_tag="PB779_001774"
     CDS             8853..9626
                     /locus_tag="PB779_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0739296.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            10034..10831
                     /locus_tag="PB779_001775"
     CDS             10034..10831
                     /locus_tag="PB779_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HDE0739297.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            10809..11222
                     /locus_tag="PB779_001776"
     CDS             10809..11222
                     /locus_tag="PB779_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDE0739298.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            11206..13851
                     /gene="mutS"
                     /locus_tag="PB779_001777"
     CDS             11206..13851
                     /gene="mutS"
                     /locus_tag="PB779_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDE0739299.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            13869..15977
                     /gene="mutL"
                     /locus_tag="PB779_001778"
     CDS             13869..15977
                     /gene="mutL"
                     /locus_tag="PB779_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HDE0739300.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRQTGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            15999..16559
                     /gene="maf"
                     /locus_tag="PB779_001779"
     CDS             15999..16559
                     /gene="maf"
                     /locus_tag="PB779_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HDE0739301.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(16644..18632)
                     /gene="treP"
                     /locus_tag="PB779_001780"
     CDS             complement(16644..18632)
                     /gene="treP"
                     /locus_tag="PB779_001780"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HDE0739302.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            18855..19568
                     /gene="treR"
                     /locus_tag="PB779_001781"
     CDS             18855..19568
                     /gene="treR"
                     /locus_tag="PB779_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HDE0739303.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            19645..20091
                     /gene="msrB"
                     /locus_tag="PB779_001782"
     CDS             19645..20091
                     /gene="msrB"
                     /locus_tag="PB779_001782"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HDE0739304.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            20261..20863
                     /gene="ruvA"
                     /locus_tag="PB779_001783"
     CDS             20261..20863
                     /gene="ruvA"
                     /locus_tag="PB779_001783"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HDE0739305.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            20876..21877
                     /gene="ruvB"
                     /locus_tag="PB779_001784"
     CDS             20876..21877
                     /gene="ruvB"
                     /locus_tag="PB779_001784"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HDE0739306.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            21906..22484
                     /locus_tag="PB779_001785"
     CDS             21906..22484
                     /locus_tag="PB779_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0739307.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            22536..23018
                     /locus_tag="PB779_001786"
     CDS             22536..23018
                     /locus_tag="PB779_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HDE0739308.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            23135..23509
                     /locus_tag="PB779_001787"
     CDS             23135..23509
                     /locus_tag="PB779_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739309.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7781 a         4286 c         5115 g         6647 t
ORIGIN      
        1 taaaaaaact tggtacgcaa tcgctgtacc aagttttttt atttagcttt tgattaagcc
       61 ataaataata atttatataa gaatactgct acgacaccag cacagatagg tgctacaact
      121 ggtacccatg catatcccca ttgagaagaa cctttatgtt tcaatggaag aagtgcgtgt
      181 acaagacgtg gagcaaagtc gcgggctggg tttagtccag gacctgtagg accaccaagt
      241 gaagcaacta atgtccatac aaggaaacca agtgctaagt gagctgtacc aagattatct
      301 tggaagaatg gtgcttttgt aatacctagg gcaccaaaga ataaaacgaa tgaaccaaag
      361 aattcattga cgaaaccatt gaatttagaa ccaacgctgt tgattgttga gaatgtacct
      421 aacacatggt ttacgtcttc tgtttggtcg tagtaaggtt tgtaacaagc tactacgatc
      481 aattgtccaa tcgctgcacc aatcaattgt gcaatgatat aaggaacaac ttcagcccaa
      541 gggaatagac cattagatgc taaagcaatt gtaaatgctg ggttgatgtg gttaccgctg
      601 attccaccaa aaatcattgc tggcatcata accccgaatc catacccgac agcaatcagc
      661 atccagtcac tgccatatcc ttttgtacct tttaaatcta cgtttgctac agcaccgtta
      721 cctagaacga ttagtaatgc tgtaccaatc atttccgccg caagacgggt cattagtgag
      781 taatccataa atacctccaa aagttataaa aatgcaaaaa aaaaagaaac atcaacacga
      841 aaagcatcgg tgcagtgttt cgtgtcggaa ggatttctgc agtcttaaca aatgtgaata
      901 aaaaaatgaa ttccattact tataagaaac cagaccaaca gtaaaactcc aactcttttt
      961 aaaagttctc cacaaatcac caagcttaac tataaatata ccaaaaaaaa aacgtttttt
     1021 ttctcaaaaa ttgtatctta gaaacagcat gttttgaaac tttcagaaaa ggtttgttag
     1081 taaaatgaaa gctatacgta aggagtgttg tttgatgaaa ttttttcaag agtttttcat
     1141 tattattttc ttttctgtat taggagaagg catacggatt tttgctcatt tacctattcc
     1201 tggaagtatc ttaggtattc tttttttatt tttagcattt gaaatgcatc ttgttgatcc
     1261 tgaaaaaatc ggagcaactg gtgatttttt attgaataat ctagccattt tatttgttcc
     1321 tgctggtgta ggtttattgg aatattttga tgatattgct tcgatatggc ctgttttact
     1381 gggagcagtc gtcgtgtgtt ccatcgtcac gatggttgca gcgggaaaaa cggcagaagg
     1441 tgtagaagct ttgctgggct atgtccgtaa gaaaaaagca gaaagggtat ctgtaaacga
     1501 aatggaggag aatcaaattg actgagtttt ttgtgaatcc attatttggc ttaagtttga
     1561 ctttaggagt gtacgtatta tctgacaaat ttttgcggaa atataaactg cctgttttga
     1621 atcctctcgt attatcgatt gttgttatta tcttattttt gcatttttct gggatcagct
     1681 ataaagacta taatatcggg ggcaattttt tgactatgct gattactcct gcgacagtgg
     1741 cacttgccat ccctctttat aaaaacttcc gtttactgaa agagaatttt tatcctgtaa
     1801 tggctgcgat tttagcagga atagtcgcaa attgcttggt tagtgtaggg ttcggttact
     1861 tcttctctct tcataaagag atggtgatct cattactacc taaatctgta acgacggcta
     1921 tttctgtcga tttatctcat acgatgggcg gggtgaatgc cgtgacactt gctattgttg
     1981 tctctacagg tatttttggt tcgctgatcg ccactcatat tttccgccta ttcaagatcg
     2041 aaagtccagt tgctcgcggt gtggcgttag gaagtacttc tcatgctatt ggtacagcaa
     2101 aagcaatcga gattggtgaa atagaaggaa tcatttccgg acttgcgata tgcgtcaacg
     2161 gaatattgac cgttttattg ctaccgttat tctttcagcc ttttgctggc ttgttttgat
     2221 gcgaaaacca ctattttatg ctacaataac caaaacgttc gagcataaaa aaggagggaa
     2281 agacgtgtat ttgtcttccg agtatcttaa acaatttgat aaagatctat attataagat
     2341 tctcctccta gaaagttttg aggatcaagc ttggcatacc gctgcacaat tagcgcaagt
     2401 tgttcagctg gatgcccgca gcgtgtcgaa atacctgaac gagctgtcta aaaactatca
     2461 gcagtttagc ggtaagacac accctttgtt tacaaaaaat caccgttctg gttataactt
     2521 ttatgatacg ctcgattcaa ttgaacatga gcgttttttg atctatctcg tgcaaagtac
     2581 gctgaaattc cagttgctgc acgacatttt ttttgaagaa ttccatacaa tgtaccaatt
     2641 tgcgcaaaag cattacatta gtgaatctac tgctcatcga aaaatcaatg aatggaaaca
     2701 gcaactgcaa acttacggaa ttcggctgca acgaggtaca tatatcgctc aaggcgaaga
     2761 agaaatcatt cgactttact tgcatatgac attctggcag ttgtttcgag ggaaaatctg
     2821 gccatttgaa acgatttctc aaatggacgt aaagaatatg gcagaacata tcatggcttt
     2881 ttttaatgtt cgtctgaacg agatcaaaaa aagacgattg gaatatatgc taggtgcctt
     2941 ttttttaaga aaatcacaga agcattatgt tgtattgaat gagaaaaaaa gacggctgat
     3001 ttctgacaat ctgttgttcc agcgattttg ccaggtcatg gagccggtat ttcctaatta
     3061 ttttcaagta gaagacgagt taggcgcatt atttcttgta ctgatgactc gtgaagaata
     3121 ttatagtgat cctaagatac ggaagaaaat ttttgatttt catcaacaag caaaaacacc
     3181 gccctttaca gccctttcag aagcaaaagc cgctctttct ctttatcagg aagagcaggg
     3241 gctgccagca gaaaatctaa ccttcgaggc agaaaactat ttattcagca gtcatttttt
     3301 cgcctatctt tttcctaatg cgaaagaaac gattgatggc aatagtagtg attttattaa
     3361 tcatttagtt attgaaaaca aggaattgaa acaatggctc gtacattttt ttgaaagtag
     3421 acacaaacat cccaatcatc tggcatttaa aaatcatgcg tttttgatgg ggcggtatct
     3481 gactgtgttt aaaacattag gagcctttac tccacagctt ccaaagatca cgatcctttt
     3541 aatgacagat ttcccattat ttgaagagca actgttagag gagggattac ggacattttt
     3601 ccgtaatgag tatcagctga tttttctgcc aacagattat cgggggagag aagttgatct
     3661 tctgatttcg acaagtaaag tccaccgcaa accatgggcg gatcttgact attttattgt
     3721 gactgaagaa ctaaaattaa ttgattacat ccaactatct caaaaatttg aaatgattca
     3781 aaaacaaaaa ctattaaaac aataacaaag aaggagaaaa aagatgacat ttgaagaaat
     3841 tttaccagaa ttgaaaaaag gtgcaaagat tattcgtaaa ggatggagtg gatttgaact
     3901 ttatgttgtt ctcgtatccg atgatgaatt tgatggctgt ccggtgacgc cgtacttatt
     3961 gatcaaaaca agtgacgaag gtttttccag cttcgctcct acagtttgtg atattttagc
     4021 agatgattgg gcgatcgtag aatgaaaaac cagtatccag atctagctaa acaggttgta
     4081 tttatcacag gagctgcttc tggaattggt gctgcgcaag cccgagcgtt tcttgaacaa
     4141 gatgcttttg tatttggatt agatcaaaag ttcggtaaaa tggaagaaat ttctttgcga
     4201 tttcctgaaa cttttgccta cgcactaggt gatgttcgac aaatgaaaga actccaacaa
     4261 gcggtatcga aatgccaaaa tcattttggt gaagttacga ttttactgaa tacagcgggg
     4321 atattggatg cctacaaacc cttgatggaa actgacgaat cgctgtggga tctgatttat
     4381 gagacgaatg tgaaaagcat gtatcagctg acaaaaatca tccttcctga tatgatccgc
     4441 caaaaaagcg gaacgatcat caatatggct tcgattgctg gcttgattgc tggtggaggt
     4501 gggatcgctt atacaagcgc gaaacatgcg attgtcggat ttaccaaaca actcgctctg
     4561 gattacgcag gacagggtat ccgagtaaaa ggaattgctc caggagccat ccaaacacca
     4621 atgaatgcgg ctgattttga agggaaaggt gagatggcag agtgggtggc aaatgaaaca
     4681 ccagtcaagc gatgggcaca gccggaagaa gtagctgagc tgacgttatt tcttgcctct
     4741 cctcaagcaa gctacataca aggaacgatc atcccaatcg acggcggatg gttgttaaaa
     4801 taaccttgtg tttttttcaa gcttctgtat gataaaacta aagagagaaa caacggttga
     4861 tgataaaaaa agtcgatgac tgttcccgac attcgatgcc gaacagccag ttcaaaaaat
     4921 tctttttaat aatcgttaat attcgaaact aagcggcttt tcacgacctc ttgatataaa
     4981 cgatattcaa aagcttgcaa ctgcggtaac aagtccagcc aaatgaaaaa tataaggagc
     5041 tatttttatt tgaccattct tattacttgt tgcagggcag ctttttcact accttctgcg
     5101 acacttcagt tggaattttc ttcccatcct ttggtcgcgg tcattaccaa gataaaatta
     5161 tcttgcaaag gagaaataga acatggaaaa aaataatacc cgttcagcca aacgctggac
     5221 aacgacagat gtgactcgga tggcgctagt cactggttta tatgtggcag tgacgctggt
     5281 tttgtctgtc tttagctttg gagtgattca gattcgtctc tcggagatgt tcaactatct
     5341 gtccttgtat aacaaaagat acatcgtcgc ggtaacagcg ggagtagctt tggctaatat
     5401 tgcttctcct cttggactga tagatgttgc agtaggaagc gtcagcacgc tgcttgtatt
     5461 gcttatcaac tataaaatca ctagtcgcat caaaaacatg aaaatcaaaa tggccgtgac
     5521 agcatgcgta tttgcttttt ccatgtttac agtagctggt cagctaacga ttttatatca
     5581 actacctttt ttcttgaatt ggtgggtgat tgctttagga gaattggcat caatgattgt
     5641 cggtgggata attatttatt ggatcggtaa aaaagtggat ttgtcaaaat aaagatctgt
     5701 ttaatttaaa atagggcagc atggaagaga ctgaatgttg agtcttcttc catgctgctt
     5761 ttttgattaa tttgtatgaa gaaatcgatt tagccgtttt ttcatcaaga taccgatata
     5821 agctgctcca gttgccttga ttgcttccgg cagtaaaaac ggcagtagtc cactggcaaa
     5881 tgcagttgta aaagtaagat caccacttat tttcagccag atcgttccgc agatcaatgc
     5941 agcaagagag cccattagat tggcaaagat tgcatataag taatgagcat ccgttctttc
     6001 gatcatccaa ccagttatcc acgtttgtaa gagaaatcca atcaaatatc cgccagttgg
     6061 cccaaataaa acagctatac ctccagtcat ccctgaaaat acaggaagac caatcaagcc
     6121 aagtaaaaga taaactccaa cagatatcaa tcctagtttt cttccgagaa aagttgctgt
     6181 taatccaata gcaaatgttt gccctgtcaa aggaaccaaa ccaaaaggaa tggtcatctg
     6241 agaaaggaca gaaataatcg cggcaaattc cgcagcaagt atcaattctt tcaatgttcg
     6301 gttcataacg ccctcttttc gttaacttaa tatttttatt tggttaacga aattgtaaaa
     6361 caaagtgatt actttgtaaa tagaaaatat aaaaaaagac cagctatcca atagatagcg
     6421 gtctttttca agaaagcttt tgaaattata agctttggtt gtagtattca acgacaagag
     6481 cttcgtcgat ttctggatat agttcgtcac gttctggtaa acgagtcaat gaaccttcca
     6541 atttttcagc gtcaaagctt acgaatgctg ggcgtccaac agttgcttct acagcttctt
     6601 ttactgttac gatgttttgt gatttttcac gaactgagat cacttgaccc acttctacgt
     6661 ggtatgaagg gatatcaacg cgtttgccat caactaaaat gtgaccatgg ttaactaatt
     6721 gacgtgcttg acgacgagtc gttgcaagtc ctaaacggta aacaacattg tctaaacgtt
     6781 gttctagtaa gatcatgaag ttaacaccat gtttaccttc tttgattttg ctagctttta
     6841 cgaacaagtt acggaattga cgttcgttca ttccgtacat gtgacgaagt ttttgttttt
     6901 cagttaattg catgccgtat tctgattgtt tgccacggct attaggtcca tgttgacctg
     6961 gtgcgtaagg gcgacgtgct aattcttttc ctgtgcctga caatgagatg cctaagcgac
     7021 gagaaatttt ccatgatggt cctgtataac gagacattaa aatttcctcc aatgaatata
     7081 agtttttgga gtaaaataat ccgttgaaaa attcataatc atatagtttg ttcttcaatc
     7141 ttcacctttg cagccgcggt tacacaatcg aacccgagac ggggcaacaa actagggatg
     7201 agttattatt tttctgctgc attattttac acaaattaca gtatatgata gatcatccac
     7261 gaatgtcaag ataattagta cataaaaacg ctttacaaac ctaggctgtc tttataaaat
     7321 gagagggtat gtgcaaatgg aaaaaagcga aggaagttta aggagaaaat caatgaatcc
     7381 ggtatcacca ttatttgaga aaatcgatgc ttcaattgaa aagaaggcga atctttttga
     7441 aaacagcttt tcacgttacg ctgttcgagc ggttctcgcc tgtttgtttt tgactttagg
     7501 aacggctgtg gcatttgcga tcgcgatgaa gggggaagat atcgcgcatg gtctaggaaa
     7561 gattttatac gcatttatgt tcagctgggg tctggtcatg attctataca tgaacgccga
     7621 attaggaaca tcgaatatgc tttatatgac cgtgggtgtt tttcggcaga gacttgcttt
     7681 aagtaaggca gccaagattc tatttgcctg tatttttttc aatatgattg gcggtatatt
     7741 atgtggattt ctaatttcta tgactacgcc atttcaagat ttaacgttgg acaactttat
     7801 gttagaatca atagcagtaa aactagcaaa accttcagca acgattttgg tggaagggat
     7861 gtttgcgaat atcgttgtca ataccgctgt actgatcagc atgcggatga aagaggatgt
     7921 cggaaaagtg atcacagtcg tattcatcat tttcattttt gcttttttag gatatgaaca
     7981 cgtgatagcg aattttcctg cctttacgct tacttacttt gcttctcacg gacagatgga
     8041 tggaatgaca gtcagcaatg tgttacataa tttgtttttt gctttggcag gaaattatat
     8101 tggtggcggt ttagtaatgg gactgggata tgcttggctg aatcagtcaa aatcatccta
     8161 tgtggactaa aaagtcgttc attaaagggg aagtgccatg gaagttttag tttttccaaa
     8221 aaatgaggaa aaagcgttac aaatggaaaa gtacatgaaa aatctttttt cctttgctgg
     8281 agtacctaag ccggaacgcg ctcttttaca acaaccgtta ctggatgaga gcaaaaattt
     8341 atctatttct gaagttttag cttttgttca ttattattat gaacaaatcg aaagagagta
     8401 tcagtatgta gcgatcgatt tagtccagaa aaacatcaaa cggcttacat ttgaagactt
     8461 agtcgtattg ttgccactag ttcagaaaaa agaatggtgg gacagcatcg actcttggag
     8521 aaaagtatac agcacatggt gtaaagccta cccagagcag cgtgaagaag tctttcaatt
     8581 gtttgaaaaa aaggaagatt tttggctacg tcgaatagca atcacgttgc aattaggtta
     8641 taaacagcaa acagacacag gactattgat ccgagcaata gacgaagatc gtcaaacaaa
     8701 ggaattcttt atccaaaaag caattggttg ggcattacgc gattatagta agaccgatgc
     8761 cgattgggta aaaagacagc tgacaacaga tttgagtaag ttagctgttc gagaggcaag
     8821 taagtattta taagaaagcg agacgacaag agatgagacg caaattattt gcttttgata
     8881 ttgatggaac gttgttagat tcaaacaaac aagctttaga tagcacaaga gaagcattgg
     8941 aaaaattacg caaagccggt catctggtca cgattgctac agggcggagc cgatttcatg
     9001 cgcaagagat cattcgcgat cttgatttta cgaactacat tttatgtaat ggagcggccg
     9061 gttttttaga ccatgaacaa gtatataaga atttactaga tcgcgaccag ttggatgcgt
     9121 tcgttcaaga agcgcatcat gagcagatcg atacagcttt tgtcagctta gacaatatca
     9181 agcgttcttc ttccaatgat gtaacggtga tggaagaagc gatgcattct ttcggtgctg
     9241 tcttgcctga attagatcag ttttttgcag aggaacaaga aatataccaa gcgttagcat
     9301 ttttcgatca aacatatgat gggaagttct cttcatatga taaaattcga tttgtccgct
     9361 ggcatgagaa cagtgtagat gtcgtaccta aaaatggttc taaagcagcg acaattctgc
     9421 acttagcaga acaagtaggc atccctcatg aagacatcat cagctttggc gatggacaaa
     9481 acgaccgtga aatgttgcgc atgtcaggaa ttgggatagc tatggggaat gctgtgccag
     9541 aagtacaagc agaagctaag atggtcactg atacaaacga tcaggatgga atttggaagg
     9601 cattgaaaga gttaagcgtg atttaaaaga ggttgtgaaa aagctgttct gcatcaagta
     9661 ataagcccag ccaaacaaaa atagctcctc ctatttttcg tttttctggg cttattaccg
     9721 cagatgcaag ctttcgaaca ccgtttaagg aagaggtcgt gacagaagtg gtcagtttca
     9781 agaaataaga agggatttac gaaaattgct tctcaaattt ttgtaaaatt acggcttatt
     9841 tctgaagaag tagatgaaac aacgtttatt cgggaaatgg gactgtgaca agatgtttgt
     9901 catagtccca tttttttatt ttatttttca aaactaagaa ataccaggaa agagttcctt
     9961 ttgtttgacc ttttctttct tattgaaaac aactataata tagagtgatg ttaaaagaga
    10021 agaggaattt agtgtgcggg tattgtttat tggtgatgta gtaggttcaa tgggacgaga
    10081 gatgattact gaatatcttc ctagattgaa gaagaagtac cgtccgcaag taacgattgt
    10141 aaatggtgag aatgccgctt ctggacgtgg aatcacagaa aaaatctata aaaaattttt
    10201 gcaagacggc gtagatgtcg tgacgatggg gaatcatacg tgggacaacc gcggaatctt
    10261 tgagtttgta aatgaagcta aaaagatggt tcgtccggca aattttccgg aagggacgcc
    10321 tggacaaggg atggtctttg tcaaagtgaa ccaagtcgaa ctggcagtga tcaacatgca
    10381 ggctcgttct tttatggtgg acttggatga tccttttcgt aaaatgaatg agctggtaga
    10441 agaagccaga aaacgtacgc cgatcatttt tgtagatttt catggagaaa caacaagtga
    10501 aaaacaagca atgggctggt ttttagatgg gaaagtttca gcagtggtcg gtacacatac
    10561 acacgttcag acaaatgatg cgcgaatttt gccaagagga acagcgtatc tgacagacgt
    10621 tgggatgaca ggtccctatg atggtatttt gggtatgcgc agagaacctg taatcgaaaa
    10681 gtttctgact gcattaccaa aacgttttga agttgtggaa caaggccgat cgattttaag
    10741 cggctgtatc ttggaattgg atgatacgac aggtcatgca aaagaaatcc agctgattca
    10801 gatcaacgat gatcgaccgt tcatggagta gaaagagagg cagttttttg cagcaggagc
    10861 cggaaattca aaaagaagta aggaaactga caaaactttt aagagagaat gaaacgatca
    10921 ttcgctacaa agaacttgaa gaaaagatcc agcaaaacca gtatttagct gagttgagag
    10981 aaaaaatcaa acaagcgcaa aaagatgctg ttcattttgc ccactatgac aaaccagcag
    11041 cagaaaaaga agcaatcaaa caagcggatc aattcatgca agaatttgat cagcatccgc
    11101 ttgttgtagc ttatagaaaa cagctgttgg aagcagatga tctgcttcat catttaacaa
    11161 ctatgataca agaagaaatc aatggacaaa tagaggagga aaaacatgcc tcaaaaaact
    11221 aaaaatactc ctatgatgga acaatatcta agcatcaagg cccaatacca agatgctttt
    11281 ttgttctatc gtttaggaga cttttatgaa ctattttacg aagatgcgat caaagcgtca
    11341 cagcttttgg aattaacgtt gacgagcaga aatcgaaatg cagaagaacc tattcctatg
    11401 tgcggtgtac ctcaccatgc agcacaagga tatatcgatg ccttgattga aaaaggctat
    11461 aaagtagcga tttgcgagca ggtagaagat ccaaagacga ctaaagggat ggtcaagcgc
    11521 gaagtgatcc agctagtcac tcctggtaca gtcatggaca gcaaaggatt gtcggcaaaa
    11581 gacaacaatt ttttaacagc tgtagttagt caaggaaatg aatttggctt tgcttatgcc
    11641 gatttaagta cgggagaatt gaagacggct cggttgcatg atgaagaagc tgttttaaat
    11701 gaagcctctg cattgcagac aaaagaactc gtattaggca gtgagatcac tgataccctt
    11761 cgtgaacagc taagcgggcg tttagggcta gtcttttctc aacaaaatga gatggaagaa
    11821 aacgcggaat ttagcttttt gacaagcgaa ctagtcgatc cgctggaaaa agaagcaacc
    11881 ggcaaactat tgacttattt atcggtgaca caaaagcgga gtttagctca tatccaaaaa
    11941 gcagtagaat accaaccaga tcattttttg aaaatggatt attattcaaa attcaaccta
    12001 gaattaagcc aatctattcg gactgggaaa aagcacggca ctcttctatg gttgttagat
    12061 gaaacaaaaa cagcaatggg tggccgttta ctaaaacaat ggctagaccg tccgcttatc
    12121 caggcaaaac aaattaaagc aagacaagaa atggtcgctt ctttgctaga cagctatttt
    12181 gaacgtatcg atttgcagtc agcattaacg aaagtctatg atctggaacg cctagcaggt
    12241 cgagtagctt tcggtaatgt caatgggcga gacttgatcc agctgaaaac ttctttagaa
    12301 caagtgccaa tgatcagagg gttgattgaa ggaatcgatc aaggtcaatg gcaaagtctg
    12361 ctttcagaaa tgcagccgat ggaccatctc gtccaattga tcgaccaagc tatccaagat
    12421 gatccgccgt tacaaataac ggaaggaaac atcatcaaag atggattcaa tgagcagctc
    12481 gatatgtacc gttctgctat gagaaacgga aagaaatggt tggcagaact tgaagcaaaa
    12541 gagcgtcaag aaacaggaat caagaactta aaaatcggat ttaaccgcgt tttcggttat
    12601 tatatagaaa ttacaaaagc aaatcttgga aatgcagaac tggagaagta tgaacgaaaa
    12661 caaactttag caaatgcaga gcgtttcatc acaccagaac taaaagaatt ggagacacaa
    12721 atcctcgaag cagaagaaaa atctgttgat ttagaatatc agttgttttt agctgtgaga
    12781 gaagaagtca aaaaggctat ccagccgcta caagtacttg caaaagcaat cagtgcagta
    12841 gatgtgctac aaagttttgc aacgatcagc gaacgctatc agtatgttcg gccagaactt
    12901 gtcagtgaca agcatcagct tctgatcaaa gacggacgac atcctgtagt agaaaaagta
    12961 ttaggacatc aggaatatat ccctaacagc gtagaaatgg cagaagacga aatgatcttg
    13021 ctgattacag gaccgaatat gtctggtaaa agtacgtata tgcgacagtt ggcattaact
    13081 gttctgatgg cgcaaatggg ctgtttcgtt ccggcaaaac aagcagtttt acctattttt
    13141 gatcggattt ttacccgaat tggtgcaagt gacgacttaa ttgctggaca aagtactttt
    13201 atggtagaga tgatggaagc caatcaagcc ctgcgttatg ctacgccaaa cagtttgatt
    13261 ttgtttgacg aactagggcg aggaacagca acctatgacg gaatggcgtt ggcccaagca
    13321 atcatcgaat atatccatcg tcatgtacaa gcaaaaacac tcttttctac tcattatcat
    13381 gaactgacgg tacttgagaa agaacttccg cagcttaaaa atgtccatgt tggagccgtt
    13441 gaaaaagacg gagaagttgt cttcttgcat aaaatgatgg atggacctgc ggataaaagc
    13501 tacggcatac atgtggcaaa gatcgcagga ttgccttcca atctactaga acgagcagca
    13561 gatatcctgc atacgctaga aaatggcgat aacggacacc atactgttcc agctgaagta
    13621 gaagagaaaa ctaaaacagc caaacaggag caaataaaac cacctgcaga aaaagtaaat
    13681 caagaccata tacaagaccg tgtaaaagaa gaaaaccaac agctttcttt attcagtgaa
    13741 ttatccgaaa atgaaacaga agtcattgaa tcactgaagc aaataaattt actagaaatg
    13801 acgccaatgg atgcactaaa cacattatat gaattacaaa aacaactgta ggaagaaggc
    13861 ggatatcgat ggccaaaatc caagaattat ctgaacgttt agctaatcag atcgctgcgg
    13921 gagaagtagt ggagcgacca gcttccgttg tgaaagaatt agtggaaaat gcaattgacg
    13981 ccggcagtac tcagattgat atcttagttg aagaagcggg actgcggacg atccaagtga
    14041 ttgataacgg agaaggcatt ttggcagacg acgtagagaa tgccttcaag cggcatgcga
    14101 caagtaagat ccataatcgc gacgatcttt ttcgcatacg aacgctgggc tttcgagggg
    14161 aagctttgcc aagtattgcc tctgtttctg aaatgactct ggaaacggcg aatcaggaag
    14221 aaaaacaagg cacctatctg tcgctgaaag gcggagaagt tattgagcat cgaccagcac
    14281 cactgcgtca aggaacgaag attaccgtca gcaatctgtt tttcaatacg ccagcccgct
    14341 tgaaatacgt gaaaacactg cacacagaat tagcgaacat cggggacatc gtcaatcgac
    14401 tggcattgag tcatccatcg attgcttttc gtttagtaca tgatggaaac aaaatgctgg
    14461 caactgctgg aaatggcgat ctgaaacaaa caattgcggg aatctacgga ttatctaccg
    14521 caaaaaaaat gctgaaaatc gaaggaaaag atctagattt tgagttattt ggctatgttt
    14581 cattgcctga ggtgactcgt gccagtagga attacttatc gacgatcatc aatggacgtt
    14641 ttatcaagaa cttttccttg aataaagcaa tcgttgcagg ttatgggtca aaattaatgg
    14701 tcggtcgttt ccctattgct gtattggaaa tcaaaatgga cccgctttta gtagatgtaa
    14761 atgttcatcc gacgaagcag gaagtccggc tgtcgaagga aaaagaacta acagagctaa
    14821 ttagtaacgc cattcaaaaa gcattgtctc aagaaaatct gattccaagt gcagcggata
    14881 atctacggtt taagaaaaaa gtacctgatc agcctaaaac agaacaaatc gaaatcgatt
    14941 tgtcctacgc ttttgaagaa gaaaaaccta aaaagccaag tagtttgaat tttgatcgac
    15001 agacaggtac ctttttcgta gaagaactaa agaacacatt tgttgacaga attgttgata
    15061 agtctgtgga aaatgttgaa aactattctg gtttttctga agaaaacacc acttatccag
    15121 aaaaaacagc gaaaacggtg gataagtttg gtgaaaatgt tgataacttt gtagaaaaaa
    15181 cagtggaaaa atctgaaaag aaagaatttc ccattgtgga taacatggag aaaacaaatg
    15241 aagaacaagc agataaatcc gtagaagagg atgaaaagat ttacgaggaa gaattgacac
    15301 tccatcctga atttgatttc actcaaggaa acgacaaaac attagaacaa gccatcaaga
    15361 aattagaaac ggaaaaacca gtacaacgtt ttcctcagtt ggaatatttt ggacagatgc
    15421 acggaacgta tctttttgcc caaagtagcg atgggttgta catcattgat cagcatgctg
    15481 cccaagagcg cattaagtat gaatatttcc gggaaaaaat tggggaagta tctgatgatc
    15541 tgcaagaatt gcttgttcca tttgtgttag actatccaaa cagtgatgct ttgaaattaa
    15601 aagagcaaaa acacttgcta gaagatgcag ggatttattt agaagaattt ggtcaaaaca
    15661 gctttattgt acgggcccat cctacttggt atcccaatgg agaagaagaa tcgattattc
    15721 gggagatgat cgatatgctg ctgacaactg gaagtgtgag tgtaaaaaaa ttccgtgaag
    15781 caacagcaat catgatgagt tgcaaacgat cgattaaagc caaccattat ttgaatgaag
    15841 cacaagcacg tgtgctgctg aaggatctgg cacgatgcga aaatcctttc aattgtcccc
    15901 atggccgtcc agtattgatt cactttacca attcggatat ggaaaggatg ttcaaacgaa
    15961 tccaagaccc gcattaagtc aaagagaaga gggaaaacat gaagattgta ttagcatccc
    16021 aatcaccaag aagaaaagag ttattggctc atatcgtttc agaattcgag attgaacctg
    16081 ctgatatcga tgaaacgcca tttccagacg aacagcccgt cgattatgtt cgtagaatgg
    16141 ctgaagaaaa agcacgaact gtctgggaac aagatgaaaa agaagaccat ttagtgattg
    16201 ccagtgacac gactgttgtt ctcaatcaag agatcatggg taaaccagaa gatctggctg
    16261 aggctgaatt catgctgaaa aaactaagcg gggaaacaca tactgtatat acagctgttg
    16321 ttttaaaaac aaaggaacga gaagaacgga tactagcaga agcacatgtc actttttatc
    16381 ctttgacaga cgaagagatc aaacgctact tggagacggg ggattatgcg gataaggcag
    16441 gggcatacgg catccaaaat gctgcgagtg tattcgtcaa agaaatttct ggagattatt
    16501 acagtatcgt aggatttccg attggtgctg tcaatcaggc actgaaaaca ttcatttaaa
    16561 caaaaaagcg gactatctga ttttcgattg aaaatccatg atagcccgtt ttttttattg
    16621 aaaagattac ttatctactc tgactaagat tttacttcag ctttaccgac tgcttcgccc
    16681 gggcgaacaa gtcctgattg gtcaagagaa agtcctgcaa ctttttcatt attggtcaaa
    16741 gcaacaataa tgtcagtttt cttgccagct tgttctattt ctggcaaatc catttcagca
    16801 atcagggtct ctggtgtgac aaggtatcct tctttcacga atacattgaa aggaacaccc
    16861 tttagttcaa cagtatctaa tcccatgtga acaagtactt ccagcccctc attagaaaga
    16921 ataccaatgg catgttttgt ttcaaagaca ctcgtcactt taccgtttac tggtgcatag
    16981 actttgccgt ttgacggttc gacagcataa ccgtcaccca tcattttttg tgagaaaact
    17041 gggtcattta cttcagttat ttccttgatg gtccctgcag cgactgcgaa taatgtttct
    17101 tttgttgcaa ctgccgtacc agttgctgaa acaggttcga aagactgtgg cgttgctgtt
    17161 gcgccatttg ctgtttgaag ttgtacatca gcagcatttt caggaacagc aggatcaatc
    17221 ttattcaaaa ttccctgacg tctaaagatg atcgtcaagc caaatggaat gatgacagca
    17281 atgatcattg cgatgatgaa aggtacccat gtttctgctt ggatagctag tattcctggc
    17341 aaaccgccta ctccgatcgc gttagctcga acacccatca agttagcaaa catgccagct
    17401 aatccagagc cgaccattgc agcgacgaaa ggatagacgt atttcaaatt gattccgaac
    17461 atagcaggtt cagttacgcc taagtaacaa gaaatcattg ctggaatcga gatttgttct
    17521 tcttttttat tcccacgatg taagaagatg atggctaaga ctgcagagcc ttgggcgata
    17581 tttgataaag caatcatcgg ccataaattc gttgatccga aatctgcaat cagctgcata
    17641 tcgatggcat tggtcatatg gtggagacca gtaatcacta aaggagcata caggaatccg
    17701 aatacggcac taaacaacca gctgatagaa gacgtcaatc cagtatttac gatatttgag
    17761 atccagcttc cgactgtcca gccgatagga cctaaaataa cgtgtgcagc taaaacagtt
    17821 ggtaacaatg aaaacaatgg aacaaaaatc atcgagatcg actgagggat atatttgcgg
    17881 aagaagattt ctagatacgc taacataaac cctgccagca tggctggaat aacttgcgct
    17941 tgataaccaa tcatctggac ttgagcaaaa ccaaaatccc aaaatggaat atctgctgcg
    18001 gctgtggaag ctacactata agcatttaat aattgcggag aaactaacgt aattcctaaa
    18061 acgattccta atatttgtgt agtacccatc ttttttgcaa tactccaagt gatacctact
    18121 ggaagaaaat ggaaaattgc ttcaccgggt aaccacaaaa aggcattgac accattccaa
    18181 aacttcgagt gttcaacgat tgttccacca agactttcaa actggatacc ttcaagtaca
    18241 tttctgaatc caaggatcaa tccaccgaca atgattgcag gaatcagtgg tgtaaagatt
    18301 tctgctaaaa cggcaatagc acgttgaacg ggatgaaggt tttgttttgc agctgctttt
    18361 ccttgttctt tggaaacccc ttcaactcca gatactgcaa cgaagtcgtt ataaaaagta
    18421 gaaacatcgt ttcctatgat gacttggaac tgtcctgcat tcgtgaacat cccttttacg
    18481 ctaggtatat cttcgatcgc tttttcgtcc gcttttcctg gatcattcag gacaaaacgc
    18541 atacgagtcg cacaatgact aactgcagca atattttctt ttccgccgat atcatgtaac
    18601 agcttctcgg catctgcttg atattttgcc atatcaataa acccctttct cttaacttgt
    18661 ctatgcaagt tgtttcttca tttactatac tttttttcgg agagaattgc aagcgtttta
    18721 ttaaaaagta cgagagaaaa tgatatcgtt ttaaaaagct taaaataagc ttttcttaaa
    18781 aataggaaca ttgaaataca aaaagagctg tagtatagtg aagaaatgat ggaagaacga
    18841 gtgagggaaa aaacatgaat aagttcaatg aaattttttt agatttggaa cagaaaattt
    18901 tagcgaaaga atatcctccg cattcgcttt tacccagtga gaaccaattg atcaaaattt
    18961 atggtgtttc acgagaaaca attagaaaag cgctgaatct tttgactacg gaaggttata
    19021 ttcaaaaaaa acaaggaaaa ggttcgatcg tactggatcg gaatcgcttc gactttccta
    19081 tttctggatt gactagctat aaagagctac aggagaccca acgtattcca agtgaaacga
    19141 tcatccatac gttagaagaa acagaagtga caaaagcatt gaacgagatc actggctggg
    19201 agatcggtgc gcctgtttgg catttgatac gcgaaagaaa aatcaatggc gaagtagtta
    19261 tattagacac cgattatcta ttaaaggaaa tcgttcctat tttaactcca gcacaagcac
    19321 aaggatcgat ctatgaatat tttgaaaatg agctttcttt gacgattgct tacgcgcaaa
    19381 aggagatcac agtagaagaa gtaacggaaa tcatgaaaac agcgatggat cttcacgatg
    19441 acacttatgc agtagtagtc agaagcctcg ttcatctgga agatacccgc tgtttcgagt
    19501 attctgagtc ggttcaccga ttagataaat tccgtttcgt tgagtttgcc cgacgccgaa
    19561 aagtgtaaat agttcaaaag aaagcaaatt gttggcatct gtccactttg gcgctatgat
    19621 aggatcacaa agggggcatt tttaatggat aaaccaataa gaccagaaaa agaagaactg
    19681 aaagaaaagt tatcacccat ggcttatgca gtcacacaag aaaatgcaac agaacgacca
    19741 tttagcggga aatatgatga tttttacgaa aaggggatct atgtagatat cgtcagcggt
    19801 gaaccgttat tcagctctgc agaaaaatat gatgcaggtt gtggctggcc atcattcagc
    19861 aaaccaataa cgaaaagaca agtgcgcgaa aaagccgatt tttctcatgg catgcatcga
    19921 atagaagttc gaagcaaaga agcagattct catctcggac atgtgtttac cgatggacca
    19981 gtagatcaag gtggtctacg ttactgcatc aattctgcct cactgaaatt cattccatat
    20041 gaaaagatgg atgaattagg ttatggggaa ttcaaatcac ttgtagaata atggaaatac
    20101 acaaagagcg gtacaatacg gggatttact cgatcgtccg ctcttttttt attcaagcga
    20161 ttgctatttg aaagaaacgc tccctagact ccttttttca caaggtgaaa tgtgctacaa
    20221 taaagggaac gtatgtgtgc aaaagaaaga ggactagaat atgtatgaat atctgacagg
    20281 tgtggttacc tttatcaacc cctattacat agtagtagaa accaatggta tcggctacca
    20341 gatcgcacta ggaaatcctt accgctacag tagcaaacta aatcaaaaaa taaaaattta
    20401 tgtccatcag gtaatacgtg aagatgcgca tcttctgtat ggatttgatt cgctagaaga
    20461 aaagcaactg tttttgcgat tagtaagtgt ttcaggaatc ggtccgaaaa gtgcccttgc
    20521 aatcatggca agcgaagacc actccggttt gattcaagca gtagaatcca gtgatgtcac
    20581 ttatttgacg aaatttccag gagtagggaa aaagacagca caacaaatga tcttggatct
    20641 aaaaggaaaa ttcggtgagc tgagtatcga tacacctttt agtctatttg atgaagcaaa
    20701 cacaaaagac gctacagctc tatctgaagc aatggaagct ctctcggctc ttggttacag
    20761 tgatcgagaa atcaaacgtg tagaaaaaca attaaaagaa gtagataatc agacaacgga
    20821 tgagtatcta cgccaagcac tcaagctaat gatgaaaaaa taaggaggag accaaatgac
    20881 agatgaatac ttgttatcac cagaatctgg cgaaaatgaa ctgagtttgg aaaaatctct
    20941 tcgaccacag ctgctttctc aatatatcgg acagagaaaa gtcaaacaag aacttcagat
    21001 ttacatcgaa gctgccagaa atcgggaaga acctttagat catgttctgt tgtacgggcc
    21061 tcctggatta ggaaaaacga cgatggccat ggtcattgct aatgagatga ccgtaaatat
    21121 tcgtacgacg agtggccctg ctatcgaacg tccgggtgac ttagtagcaa tcttgaatga
    21181 actggaagca ggggatgtcc tgtttatcga tgagatccat cgattaccta gagtggtaga
    21241 agagatgctt tattcagcta tggaagattt ctatgtagat atcatggtag gacaagggcc
    21301 aaccgcacat ccggttcatt tccctcttcc tccctttact ttgattggcg cgacgacacg
    21361 ggcaggtatg ctttctgcac ctttacgaga tcgatttggc atcatttctc atatggaata
    21421 ttatgacgaa caggatctgc aggagatcgt tttacgttct tcggatattt ttcaaacaga
    21481 gatcattgaa gaaggggcat tggaaattgc tcgccgatca cgaggaacgc ctagaatcgc
    21541 taatcgcttg ctcaaacggg ttcgtgattt tgcgcaagtc caaggagacg ggaaaatcga
    21601 tcgtcctata gcggatcagg cacttacttt gctacaggtc gatcaggctg gattggatta
    21661 tgttgaccag aaattgttgc gaacaatgat cgagttatat ggcggcggac cagtagggtt
    21721 aagtacgctt tcagtaaaca taggagaaga gcgtgagacg gtagaagata tgtatgaacc
    21781 gtatctgatc caaaaaggat ttttaaagcg tacacctaga gggcgaattg ctactgctta
    21841 tgcctatgaa cattttggtt acgactatca tatatgattt ttgcttttag attggaggaa
    21901 aatgaatgag tgatacaaca cgtacgaaac aattgatcaa aaacgtattg attgatttgt
    21961 gccaaacgca atcttttcga aaaatcagcg tccaaaaaat cgcaaacgaa gcaaaaatca
    22021 atcgacaaac attttattat cattttacag ataaatacga tttgcttcgt tgggtctatt
    22081 gtgaggatgc attgcattat ttagatccac aatgtctttc acttgataat tgggaagagc
    22141 aagcattgaa aatgctgaaa gcaattgctg agaagaaaga attttatgca aatactgtgc
    22201 tttctgaccc agaaatttta caaaaagagt tttctcaact gatccaaaaa tcatttatca
    22261 agatttttga acaaatggat gaagaaagac aactttctgc aagagacaaa ctattttatg
    22321 ctcgtttttt ttcttacggt tgcagtggtg tattagtcaa ttggatcacg aatgaatatg
    22381 aagaaacacc gatggaaatc gctatgcagc ttttccgttt agccaaggat acggaattat
    22441 attcttatcg tctttatgca aaagaagagt tggaagaaca gtaatagaaa aattttttgt
    22501 tggaaaagca ataatcgcta aaaggagatg gggaaatgac aaaaatttta tttgtttgtt
    22561 tgggaaatat ttgccgttca ccgatggcag aaggcttgct gagaaaacga atagcattag
    22621 aaggaaggga agcagaattt tttgtggatt ctgctgctac aagcacgtat gaagttggaa
    22681 agacaccgca ccctggaacg aaaaaaatat taaaccaaga aaaagtagat atgacgaata
    22741 tggttgctcg gcaaatcaca ccccacgatt ttgaaacttt tgattggatc attggcatgg
    22801 atcaagaaaa tgtagaagaa ctgaaacgaa gagcaccacg ctcagcgcag gggaaaatcc
    22861 atttgttttt aagtagcatt cctggaaaag aaaaagaaaa tgttcccgac ccatactata
    22921 ccaataactt tgatgagaca tatcacttga tcacagaagg cctgaatcat tggtggaata
    22981 tttggattga tgaaaataaa ataacaaaca atttgtaaag ttaacgcttt ctttttaagg
    23041 cgatgttaga gcatttcctt gtttttttgt aaaatgttag gtaaaataaa attaattaag
    23101 taacactttc ttagctaaag gaggagtgca ttcgatgaac gaagagacag tatcgccaat
    23161 gaagaagctt acgaagttag ttactcatac ttcgtatcaa ctttttgatt cttttgtaaa
    23221 tgacactgaa gaacatgcta agaatgtacg attgcaagga aagtttattc ttgagctgca
    23281 aaaagctgct actgaacata gtctagttat cttacaagta agagcaaatc gtttgagtag
    23341 caagtatgaa acgatctcag gctgggtggc gacaaaaacg gtcgaaaaag accgagtgat
    23401 gatccgccta caaaacgaag agcagcagat ccggatggtt cctgtagaac aaattgaaaa
    23461 aataacaatc ctttcaccag caggggaaca ggaacggtta tcaaaataat ttataccaga
    23521 tagaaaagca cgtatgagct tgtaccatca atcattacta atcaaaaata accgaatgct
    23581 ttaagctgat atcagtaaaa cggaacgttt taggatgagt atcatagcat gacagcattc
    23641 ggttgattag ttgaatcgat tggatggtac aagttttttt gataaaaaaa ggtcctgcta
    23701 gccggggagc tagcaggata aggagttaaa aatgaaaaag tgttgttagg gttgtttgtt
    23761 ggtatgctta tataatagtc attagttgtg aatattttgt gacgaaagtt ttcgaaagtt
    23821 gttaagttt
//
LOCUS       DAMEEU010000047        23777 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.048, whole genome shotgun sequence.
ACCESSION   DAMEEU010000047 DAMEEU010000000
VERSION     DAMEEU010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23777
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.048"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(383..1849)
                     /locus_tag="PB779_001788"
     CDS             complement(383..1849)
                     /locus_tag="PB779_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0739310.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
     gene            complement(2140..4224)
                     /gene="cadA"
                     /locus_tag="PB779_001789"
     CDS             complement(2140..4224)
                     /gene="cadA"
                     /locus_tag="PB779_001789"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HDE0739311.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQETKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKKFMQYIASAEQFSTHPIAQSVLEGYAGPLLP
                     TTNIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPLSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKQAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKKEDE"
     gene            complement(4749..5108)
                     /locus_tag="PB779_001790"
     CDS             complement(4749..5108)
                     /locus_tag="PB779_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HDE0739312.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            complement(5138..5479)
                     /locus_tag="PB779_001791"
     CDS             complement(5138..5479)
                     /locus_tag="PB779_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739313.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERVDQRPSGKLIQHTLVTKENTEEIQKKFAEYLMLEAK
                     KRRIKSIFAQF"
     gene            complement(5476..6150)
                     /locus_tag="PB779_001792"
     CDS             complement(5476..6150)
                     /locus_tag="PB779_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDE0739314.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     KFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTAEICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIAYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            complement(7326..8624)
                     /gene="asnS"
                     /locus_tag="PB779_001793"
     CDS             complement(7326..8624)
                     /gene="asnS"
                     /locus_tag="PB779_001793"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HDE0739315.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            complement(8664..9854)
                     /locus_tag="PB779_001794"
     CDS             complement(8664..9854)
                     /locus_tag="PB779_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDE0739316.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYPLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            complement(9875..10402)
                     /locus_tag="PB779_001795"
     CDS             complement(9875..10402)
                     /locus_tag="PB779_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HDE0739317.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEETDHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            complement(10449..13238)
                     /locus_tag="PB779_001796"
     CDS             complement(10449..13238)
                     /locus_tag="PB779_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDE0739318.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLVQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            complement(13385..13585)
                     /locus_tag="PB779_001797"
     CDS             complement(13385..13585)
                     /locus_tag="PB779_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HDE0739319.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            complement(14038..14358)
                     /locus_tag="PB779_001798"
     CDS             complement(14038..14358)
                     /locus_tag="PB779_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739320.1"
                     /translation="MKKRLLWCLLSLSLSLTSQPVFAEETQRFPITGTRLYKNVYVQT
                     PDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            complement(14861..15979)
                     /locus_tag="PB779_001799"
     CDS             complement(14861..15979)
                     /locus_tag="PB779_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739321.1"
                     /translation="MAKKDKELLSQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            16450..17757
                     /locus_tag="PB779_001800"
     CDS             16450..17757
                     /locus_tag="PB779_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HDE0739322.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWDDKVSISDYAENLSVT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETARLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAE
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
     gene            17878..19077
                     /locus_tag="PB779_001801"
     CDS             17878..19077
                     /locus_tag="PB779_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDE0739323.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYSSTWTFAVI
                     LTYFVVLEIFYSTFYFLIPLVFFSIFAFSYFSEKRRLLNGLLFNIFLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVFLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCIPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYWAQSRATLNPPILLMSGGQGADEKVPE
                     AMAMKQYAMEQGIPERDILVETNSTTTLENMRYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYIAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(19104..20372)
                     /locus_tag="PB779_001802"
     CDS             complement(19104..20372)
                     /locus_tag="PB779_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HDE0739324.1"
                     /translation="MEKQLPSPVRILMYMLKWLVVTAILGVFMGSLSAFFLNSLTFVT
                     DIRLAHPWLLYLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNIAHLFRLDKAEREILVISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVWRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHAYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAVLA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAAYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRIKEKNKV"
     gene            complement(20542..21183)
                     /locus_tag="PB779_001803"
     CDS             complement(20542..21183)
                     /locus_tag="PB779_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HDE0739325.1"
                     /translation="MEQTMKPYQYFFIKREVEQLLNAYSSVNDSKTVQTVQALAAEKI
                     RDVLGYEPSEIDTFLTTVLDVKLTKTQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQAHTYIGWNDPGTQKKFMVYYEDGKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKK"
     gene            complement(21592..22095)
                     /locus_tag="PB779_001804"
     CDS             complement(21592..22095)
                     /locus_tag="PB779_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDE0739326.1"
                     /translation="MTEKWREDEEYMSYVEDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(22218..22982)
                     /locus_tag="PB779_001805"
     CDS             complement(22218..22982)
                     /locus_tag="PB779_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HDE0739327.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKEEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAANKEISTFLVSDEVMDAVSDLPTPQGILAVMALTAE
                     GTPDFSGGWLLLDNVQDPGNVGTMIRTADAFDMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLTEVIPLMKDKGFTVYGTELNEEAHALDKVEKSDNFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            23090..23365
                     /locus_tag="PB779_001806"
     CDS             23090..23365
                     /locus_tag="PB779_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HDE0739328.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
BASE COUNT         6878 a         5065 c         4151 g         7683 t
ORIGIN      
        1 aatggtgttc aatcagctga ccttcagcat tagctcaaaa agcggcaaaa tatgaggagc
       61 tatttttccg tttgtttctc taatactcag gtcaaatcgc tgattttaca acctcttcct
      121 taaacggtgt tccaaagctt gcatctgcgg taataagccc agccaaacga aaaatatgag
      181 gggctatttt tgtttggctg ttcttattac ttgatgcagg acagcttttt cacaacctct
      241 gattcacggt gttccagaag tagcttcttc gaaaaacaag ccgaaacttc acaaaaattt
      301 gagaagcaat tttcgtaaat tccttcttat ttcttgaagc tgaccacttc tgtcacaacc
      361 tcttgtaaca agtatttcta ttttaaggct gaaccactgt ttctggttca gtgatttctt
      421 tgtttttgtc tcgacgagca attgctggca agatcatacc taataagatc aagacgattg
      481 gtgtgatgat attcgtaaat aattggaacc accatgcttt aggatcagca gtataatcta
      541 cttttggcac cattcctagg atacatgcaa acgcagtgaa ggcaaagcac caagcaccaa
      601 agataaaacc gatttttgga tttttaacaa atttatattc agaattgaat ttcttataag
      661 ctttattcaa catcatatat gccaagaaca cccataggta acgcattggc atgacaactg
      721 agttcaagtt cgtcaaccat tttactaatt cattcatatc tttgatacca aaaatcggca
      781 acaaaataat gattcctact agtatacctg tcagaagata accattcacc aatgtacctt
      841 tacgattacg tttacgtagc cagtttggta caaattctgg atccgcatct gctaacaaga
      901 tttttagtgg tgcatcaatt gaaaaggcta atgcggagat ttgtccaatc atgtttgtca
      961 atgcgtaaat gatcatcaat gagttaccga taccatagta attacctaaa atttgaaaag
     1021 cactgtatgc cccatttgcc atcaagtctt taggaatatt atcactagca aacagcatac
     1081 ccattgcgac tgagcctaat acagcacaaa tccctaccat tgctgctaag aagatcatcc
     1141 ctttaggaaa ttcctttgca ggatttcttg tagagttgac ataaggggat attttttccg
     1201 cccctccaac tgcaaatact agcatcgaaa cggttgtgaa ataactgaaa tcaaatgttg
     1261 gaatatatgt tttcacttga ttcatatgtg gtgtggcaaa ttccatcgtt ggattgatga
     1321 acggtgccgt tacagctaaa agaataaata agatcgacat gacgaacatc gctgttccgg
     1381 ccagtccgcc aatcactttc aaagtagaaa gtccttttgt tgataaatat aaaaaggcaa
     1441 gaaatataat aagtgaaata actgctacca tttgtactga catcgtattt acgatatttc
     1501 catttccttg gactgcccaa ccaccagcaa tcagaattgc ttgaggcttt tgtgccaaat
     1561 aaggaatatg gacgacccag taagtccaag cggcatagta tgccagtcgt ttattagatg
     1621 tcgtattttc gacccatgaa ctgacgcctc ctttactatc cttgaaggct gatcctaatt
     1681 gtccaacgat caatgcgtat ggaataaaat aaatggccaa aatcaatagc caagaggtga
     1741 caactgatac tccttgctga gcatagttat taactacatt ccccatgccc caaaccatgt
     1801 taaatgcaat taacgcaaca gtaaaccagc gtaattgttt gttgttcatt cgttctctcc
     1861 tttatgataa aaatttgtta tccagatgta atcatattca atttttaaca aacttacaag
     1921 acagtgttat tttatgtgtg tattctttta tttaatacac atcgtttttt catatttttt
     1981 ccatcaaaaa aataagttat tttcttttat ttcattgacc ttattgaatt tcaagctatt
     2041 ttgaattttc tgcaaaatta aaaacattag ttattttata atcctatcta ttttttttac
     2101 atttttcatt aagaaaagga tataaaaaaa agaggacgtt cattcgtcct ctttttttac
     2161 atgcaagctt cgcatggcat tcaaaacagc taatactgtc accccaacat ctgcaaatac
     2221 tgcatctccc attgatgcaa aaccaaaagc acctaaggca agtaccaaaa tttttatccc
     2281 aatagcaaag acaatgtttt gtttgacgat tttcaatgtt ttctttgcta aatggattgc
     2341 ttctgcaatc ttcgatggtt gatcattcat gatgactaca tctgctgctt caattgcagc
     2401 atcgcttccc aatccaccca ttgcgattcc tacatctgct cttgctagca ccggtgcatc
     2461 gttgattcca tctccgacaa atgcggtctt tttattgttt ctttgtaaga tttcctctaa
     2521 ccgctgcact ttatcttcag gaagcaattc gctatatatc ttgtccacgc ctacttgctt
     2581 cccgatatga tcagcaattt ttttcgagtc gcccgtcaac atgactgtgt tcttcacacc
     2641 agcctgtttt aattgaacca atgcgtctac ggcatcttct ttcaaggtat ctgcaataac
     2701 aagataacca ctgtaacttt gatcgatcgc tagataaagc aatgtaccga tttcttgact
     2761 taaaggaaaa gagatttcaa atctttccat caatttgtga ttacctgcta atacttgttt
     2821 gccatcaact tcagctaaga tcccttcacc tgcaaattcc tggatattag ttgttggtaa
     2881 aagcggacct gcgtagcctt ctaaaacaga ttgagcaatc ggatgtgtag aaaactgttc
     2941 tgcactcgca atatattgca tgaatttctt tggatcgatt tttgtatcga tcgtctggat
     3001 cgaaaagtca cctttcgtta atgtgccggt tttatcgaat accactgtct cggtttgcgc
     3061 aagcaactcc aagtaatttg aaccttttac taatacaccg attttacttg cgcctccgat
     3121 accgccaaag aaactaagtg gcacggaaat cactaatgca catggacatg agatcactaa
     3181 aaatgtcaat gctcgataga tccattcaga aaacgccgct ccagaaacaa caagtggagg
     3241 taaaacagct aataaaacgg ccaatcctac aacgactggt gtgtaatagc gcgcgaattt
     3301 agtaatgaaa ttttcagctg gtgctttttt actgctggca ttttctacta attctaataa
     3361 tttgctgata gtagaatttt cataagattt ttctacttga actaaaaatg gtttattttt
     3421 attgataaat ccgcttaata ctgtttcacc aacatataca gatttaggga ctgattctcc
     3481 tgtaagtgct gacgtatcga ctaatgattc tccttcgatg atcgttccat ctaacggtac
     3541 acgttcacca ggcttcacaa gtacaaactg accgatctgc acgtcttcag ggttcacggt
     3601 catcaatcct tccgtcgtct gcacgtgagc tgtttctgga cggatcgcca tcaattcgcg
     3661 aatcgatttt cttgaatgac tgactgccaa tccttggaaa tactcgccga tttgataaaa
     3721 tagcatcact gctacggctt ctggatattc accgatcaac atagcgccaa tcgtagcaac
     3781 agacataaga aaattctcat caaagatttt tcctttgacg atattcatca ctgccttctt
     3841 cactacatca tatcctatca gcagataaat caataaatac cctatcaagc gaattggttc
     3901 attaaaatca aataatagca ataaagcgat acctgcaagg gaaaataaaa tccggaacag
     3961 cgtatttctc tctttttcat ttccatgttc agatactttt tccttatcta tttctgttac
     4021 tttgacatct ggttctaatt ccttcactac tttttttgtt tcttgttcaa tcgtagccaa
     4081 atgatcttcc tctgcgtcaa tcgttagttt tccagaagtg aagtttaccg ttgcttcctt
     4141 gactccattg atcttctgaa ctcctttttc gattttcatt gcacagttcg cacaatctaa
     4201 accttctaat ctgtaacttt tcattttaat gacctcctcg cctcaacata tgaacatctc
     4261 ttcataacta attataaatg aatggttatt catatgtcaa ggtatccgaa agaaaaaatg
     4321 aaaaacatct gcatcggaaa atttcttcca tacagatgtt ttggcttatt ctttcttttt
     4381 ctcttcgatc attgcccctg ctcttatcca acccgcactt gccttcttga tcttgacagg
     4441 atagcaacta agtttgaagc ctgttgctgg caatttgtct aaattcatta atttttcgat
     4501 aggacaatat cttttttcaa tccctgcaaa atgtccttcc cagatattcg aagctccact
     4561 acgctttcaa aaatatagaa agagttcttt aatgaaaatt atttcaactt tccataaaca
     4621 gtaatcccat ataaataaaa gacgtaaaag tcacatggga gaacttatac aggaaaacac
     4681 atagagtcag gtgaaataca tgtatcccac ctgactctat gcgttttcta acctttatta
     4741 ttctcttttt atacaatttc tgcaccgaat ggcatcaacg ccaatcgagc aagtttgaaa
     4801 gattgcttgg caaaaggtat ccctatgatc gtgatacata gaaggatgcc gctgacgaca
     4861 tgtgcgagag caattggtag gcctgaaacg atcagccaga tgatattaac gatcaatgac
     4921 atgccagact ggtgataaat tacttctttg ccaaaaggcg caaaagaaag ggaggcgatc
     4981 ttaaaacatt gcataccgat tgggatacct atgatcgtga tacaccaaag tatccccgct
     5041 gctaaccagc taagaccacc gattagtccg ccgaatataa accagatgac atttcctaaa
     5101 caactcattg tatttctcct tctattactg tttttgatta aaactgggca aaaattgatt
     5161 ttattcttct ttttttagct tccagcatca agtattctgc aaattttttt tggatttctt
     5221 ccgtattttc ttttgttact aatgtgtgtt ggattagttt tcctgatggt cgctgatcca
     5281 cccgttcttc tgactgttgc acgtccgctt gcgcaaatcc gataatccgt ttttcttttg
     5341 ttacagcaac gagcaatagt ttattcttat catttaggtc agctgccgtt tttgctttta
     5401 cgaatgattc tggatgatca gtaatcagct gattgatttg aggtaaatct tcttttactg
     5461 cccaccgtat ttccatcatt tctcactttt ctttcgctca tttttatctc cactaaaaaa
     5521 atcgactgcg gcaattgcat ctatccagct ttgtgcaatg atctcatgtc cgccaatcgt
     5581 tgggtggacc ccatcttctc ttgtatattt cgaaaaacca taagcaatcc ctaaagcatt
     5641 gaatatgcca tctaaaggaa ccagcaatgc gccatattcc ttagcaagtt tacgaacaat
     5701 ttggatttta gggtctaagt ctttacgcca gccatgacgg tcgtcggtta taggaagtac
     5761 aaacggctcc atcaagatga tgttgcagat ttccgctgtt tgaagttcat ttagtaattt
     5821 tcgataaacg gattcaaatt gctgcgcaga tttctcagtt ccgaatatag cctgatcgct
     5881 agtattatgc caggtatcat tgattccgat caaaatcgat acatagtcag gttgtaaagc
     5941 taaacaatct tcttgccagc gtacttgcag atctgcaatt ttgtctcctc ctatcccacg
     6001 gttcatgcat tcaaatttca tcgttggata ttgggagatt agttttccgg caatcaaaag
     6061 tggataacct ttacctagat cagttgcttc tgctcggtct cttcctgcgt ctgtaatgct
     6121 gtcaccgata aataatatac gttttttcat ttgtcaaaaa ctcctttttg aataaaacga
     6181 tgattttctt ccttatatta tcccataagc cctatcaaga cgaaagagaa aatatatgta
     6241 taaaaaatga caccagccta gtcccttcaa tcaattgaat gaacgctcat caagtgtcta
     6301 gttttttata ctttttttct taacgtgccg gattcccctt gattccttcg ttgtttggtc
     6361 cagagaaatc gatcacacct aagcttccgt caatcagacc actgatgacg ccatcagaac
     6421 atatatttat aggctcatct aagacttcca gtaaatgttc ttttactaat atctcttcta
     6481 gattgcttgg gatagattgg tcataacttt atctggtccg atgatttcaa ggatgaatta
     6541 aacttacata tggatcattg catgctgaaa atacggacct actccatctt cgaatgttac
     6601 tattagtttg ttttcaggta ctagatgctg ctttatttca acagcagaag catcatcaaa
     6661 tcagatttcc atttgaataa ccttctttgt atatgtttga ttgattgcga tttcgttata
     6721 gaaccttgtg aatcaaatag caatttcttt tgctttcttc tcttgtctgc tggaaacttc
     6781 ctttatcccg tattttaaaa aaagaactgc gagagttcgc agttcttttt tttaaataaa
     6841 cgttgctctc cggccaactc ctcggtcaca agtcacaata gtcatcaaac atgaaaaact
     6901 gttttttgaa attactcctt gtgactcgga gctgaacggc aggcgcacaa cctcttgata
     6961 taaacggtgt tcaatcagct gaccctcgat attagctaaa aaaacggtaa aatatgagaa
     7021 gctatttttc cgttttgttt ctctaatact caggtcaagg cactgatttc acaacctctt
     7081 ccttaaacgg tgttcaaaag ccagtttctc ggtattaagc caaatttatg caaaaatgtg
     7141 gaaagccatt tccacaaaat ttttcttaat actcgaaact aaacagcttt ttcacaacct
     7201 ctccactaaa cggtattcaa aagcttacat ctgcggtaat aagtcccgcc aattcaaaaa
     7261 catgaacagc tgtttttgct tggctgttct aattacttga tgcagaacag ctttttcatc
     7321 acctcttatg gataaattcg gttcaacaaa cgtgggaatg gaatagcttc acgtacatgg
     7381 tcgataccag caatccaagt gactgttcgt tcaaggccta gaccaaaacc agagtgcgga
     7441 acagaaccgt atttacgtag atcaagatac catgaatatt ctttttcatc caaaccgtga
     7501 ttacggattt gttctagcaa gaaatcatag tctgttgccc gttcgcttcc gccaataatt
     7561 tcaccgtaac cttctggtgc gatcatatct gcacaaatta ccacgtcttc tcttgttgga
     7621 tgtggtttca tgtagaatgg cttgatggct tttggatagt ttaggataaa gacaggctgt
     7681 tcgaatgaat tcgcaatgaa cgtttcatga ggtgaaccaa agtcttcgcc ccattcgatg
     7741 tcatcaaatc catttttctt cagtaattcg attgcatcat cgtaagtaat acgagggaat
     7801 ggcaattttg tataagtttt taagacttct ttgtctcgtc ctagtacatc taatgcatat
     7861 tcgcaatgat ctaaaacatt ttgtactaag aatgctacat attgttcctg tacttctaaa
     7921 ctttcttctt gatgagtgaa agccatttct ggttcgatca tccagaattc gatcaaatga
     7981 cgtcgtgttt ttgatttttc agcacggaaa gtcggaccga atgaaaagac ttttccgaaa
     8041 gccatagcag cagcttccat gtataattgg ccactttgag ataaataagc tttttgatca
     8101 aagtaatttg tttcgaatag atccgtagtg ccttctggtg cagaaccagt caagatcggc
     8161 ggatcgattt tgacaaaatg atgttgatta aagaattcat acgttgcacg aatgatttca
     8221 tttctgatct gcataatcgc atgttgtctt gaagaacgca gccataaatg acgatgatcc
     8281 atcaagaaat ctgttccgtg ttcttttggt gtgatcggat aatcgtggct ctcgcttacc
     8341 acttccacat ttgtaattcc gatttcataa ccaaattttg aacgactgtc ttcacggatt
     8401 tctccagtta ctaacacgga tgtttcttgg tgtagatttt tagctgtttg gaaaacttct
     8461 tccgacactt cgctttttac aactacacct tggaaaaagg ctgttccgtc tcttaattgt
     8521 aaaaatgcga tttttccgct tgatcgctta tttgcgaccc aagcgccgat tgttactgtt
     8581 tctcccacat ggtttttcga atcgatgatt tgaatttgtt ccacgtatga ctctcctttt
     8641 atattccttg aatttcttca ggattaattt tgacttttac tctcaataaa ttgcttgatt
     8701 ctgcgtaccg cttcttctaa cgtagcgcga tcagtggcat aactcatgcg gacattttct
     8761 ggtgccccaa agccttcgcc agtcacaagc gctacccctg tttcttctaa aagatcttct
     8821 acccattgtg tgacattttc atacttacac atgcgtagcg tttcttttac attaggaaaa
     8881 agatagaaag ctccttgcgg cttttcaaga gaaacacccg gcagttctgc cacaagcgga
     8941 tataacgtat tcaggcgttc ttcaaaggcg ttccgcattt cttctactgt atcttgctca
     9001 cctttcaatg cttcaacagc tgcatattga ctgactgctg tcggattgct agttgattgg
     9061 gaagcaacag cgatcattcc attgatgatc acaggatttc ccaccgcata accaatgcgc
     9121 cagcctgtca tcgcatatgt tttagacacg ccgttgatga tgatggtctg atttttgatt
     9181 gcttctgaaa tcgttgcaat tggagtaaac tcattgccat tataaactaa acggccataa
     9241 atatcatcag caactatcaa aatatcattt tttactgccc attcaccgat tgcctgcagt
     9301 tcattcttgc tataaatcat tccagtcgga ttcgatggag aattgatgat tacggctttt
     9361 gttttttctg aacgtgcttg ttctagctgt tcaacagtaa ctttccagct attggattct
     9421 tcccctttca caaagacagg aagtccttct gccagtttta cttgctcacc gtaactgacc
     9481 cagtaaggca caggaatgat gacttcatct tgcgggtcaa ggatcgtttg gaaaagggta
     9541 tacaaagcaa atttcgctcc gtctgttacg actgtttgtg aaggttcata gacaagtcca
     9601 tagtttttct tcagataatc aacgattgcc tgtcgaagct ctgggattcc tgctgttggt
     9661 gtataatagc tagctttccc attgcggatt gcttcgattg ctgcttcttg gatgttttct
     9721 ggtgtcgcaa aatccggttc tcccacagtc aaactcagca catctctgcc ttttgctttt
     9781 aatgccttgg cctttgccgc agctgccaaa gtgacagacg gttctaatcg ttttgttctt
     9841 tttgataact ccatcccatt cattccttta ccttttaaat tcccttgatt gtcttgactt
     9901 catctccaga ttcaaagcca atcaggtaat aattcagttt cccatttgtt tcttttccta
     9961 ctacttccca cacaggctga tcatcataca tccctaaagc agctttttcg atttggattt
    10021 caggatgggc cgcagcaatt gtctgttttg cttcgttttc agtcagtccc tttgtttgat
    10081 ccaatacttt tactttttca ccagatttag gaatgataac ggcgatttct tttcctttat
    10141 catttgtacc tgtcagtgaa aagtatgtct tctttcgagt aaaccaataa aaatgatcgg
    10201 tttcctcaag atttgcatat ttctttgcga tttctactgc ttctttcttc gcctgcaccg
    10261 ccggacgact ggaacgcaag taaaaaatcg agctgatcac gatgaccgct aataaaaata
    10321 cgatcaagcc aagtaacacg cgattaatcg ttttttcctt tgtctgtttt ttcttcaagg
    10381 gtcgtcgctc ctttatcttc attccttttc attatagcag attttaatta tgaaaaaaga
    10441 cagctcctct aacttccttc ttcatttttc tttaagaatt catggatatc ctgatagatt
    10501 tcctccatag ctagctcttt gatcggtact tttttcggta atgcatggat gatccgtgcg
    10561 ccatattttg cagtgactag tcttcgatcc aaaataagca atacgccacg atctgtctcc
    10621 gtccttatca agcgacctaa tgcttggcgt aacttcaaag ctgctttagg tacggattcc
    10681 tggtaaaaag gattgatccc ctctgattct aaataagcgt tcctagcttt gaccatcggg
    10741 cgaagcggat tatcgaaggg taaacgtgtg actacaacga tctgcaaagc atctccaggc
    10801 aaatctacac cttcccaaaa gctgtcagcg ccaaacaata cgcttttttc tgacaaaatg
    10861 aagcgtttca aaagcttctc ccggcttcca ccaaaccctt gagctagtat ttctcgtcct
    10921 ttttctagca tagacagatg cattttctga tagaccttct gcaaaacatc atgagaagtg
    10981 aataacacaa gtattggccg atcttcttgt tcgatcagac ctgtaagtgc tgtctctaaa
    11041 taatcgatat atgcttgatt gctgacttga tggacggcag gtgcctcttt tggcacatag
    11101 atccttgcct gtttctcata atcataagga gaggcaatca ctttaagagg tgctgcttca
    11161 atgccaagcc tcttagagag atagtgtcga ttagggccga tcttcagcgt tcctccaata
    11221 taaagaatac gatcatatcg aggataccaa acagtcgacg gcaacatagc cgcttgaaaa
    11281 tcatggagat gaaaaatcat ctgctgcgct gtgttcccag gaacgaacca atggatcaaa
    11341 tgatctcgcc agtcttccag ccattgatcc atcagcaagt attgcttgtc taattgatca
    11401 aataggctat ataaacttgc taaatcgatc cgcatctggt ttgtccagct ttcttggata
    11461 atctcaaaag tcagacgcat ttgtgactgt agctgctgga tctcctgata aaaaagctgc
    11521 aggtgatcaa tggctgtccc agattccagt ggcagctgat ccaacatctc ttttgtcatc
    11581 atgacttctt ctggatactg tccgttaggt tgcttgccgc tcactaaact cattaatcct
    11641 tctgccatac aaatctgtgc ttcgcatagc gcagaaagtt cttctcgata aatcgataac
    11701 cagcgtaagg cttcatgttc tttcggtaaa tagctttgta ttcggtcaaa cagctgattt
    11761 ggttcttcta attgctggat ttgtttatgg aaatagttaa tacttaatcg tttgtcattt
    11821 actttttcag cgatttccgg caaatgatgt acttcatcga tcaacaaaaa tggactagct
    11881 ggaagcaatg gttcttttcg ctgtgtttct tgtactaaaa acgcatgatt gacaatcaaa
    11941 aaattacttt gcctgatttt cttttgcaag aaacgaacaa agtcttgttc gtaaaatgac
    12001 tgatttcttg ctaaaaatcc aatacctctg tgcgcgatat ctgcaaagaa tgaatggttc
    12061 aaatttgtta aatgtaattc atccaaatca ccagtcttcg tttgcgtcag ccaaactaag
    12121 accgccattt gatacaaagc atattgtttt tgttctggcg gttccacaag tgtgccttta
    12181 aaacgctgca aatcaatata gtggcgatag cttttgataa ttacaggttg tatgggctga
    12241 tctagcaatt gattcagcaa tggaatgtct ttttctatga tctgctgctg caaaactagc
    12301 gaaacggtac tgatgacagc gggtttttca ggtgtagcca aataactcaa tggcagcaga
    12361 taaccgattg ttttacccat tcctgtagct gcttcgatca tcaaatcttt tgattcatct
    12421 tttgtgaaat ggtcgtagac cgcattcatc agtctgttct gttcttttcg atacatcagt
    12481 gttttaccaa acattttttc ttttgcttgt ttttttcttg gatatgtccg ctcgccataa
    12541 tggacggatg tgaatagttc cacttctttt ttctgcaaag ctagcccatc gacgatttct
    12601 aatgagggat caagtggctc tggtttttct ttcatttctt caatcacatg ataaatgaaa
    12661 cgactcgtat ccatacctgt gtgtctactt aatcgcgcaa tctgctctaa cgtgatgatt
    12721 ggcaattttc tcatccgttc ttcgatcagc aaaagaagtt gacctgtcac ttcggcatca
    12781 ctatctgcct gatgaggatt ctcatgaata aatccaaggc tttctgacaa atcagctaag
    12841 cgaaagcttg gttccgtcgg caagaaaatt tgtgcaagtt ctactgtatc gatgcctggt
    12901 atcttcaaac taggaagtcc gcatcgcatg agttcatggt tcaaaaaatt ataatcaaaa
    12961 taaatattat gcgcgacaaa tatggtgtct gccaaaagat tgtaaatcgt ttgggcgaca
    13021 tcttcgaaat aaggcgcttt ttggacgcgt tgattcgtga tccctgttaa atgctggatt
    13081 tgttttgaaa tcttccgccc tggatgaata tcgatcgaaa aacgtgaagt gatccgacct
    13141 gattcaatca tgacgcagcc aaattggatg atccgatctt cttttggatt cgtcccagtc
    13201 gtttcgatat caacgactgc ataagttctt ggtttcaaaa tatcttcctc ttctcctgcc
    13261 tctaatgttc ttttgaaatt atactacaaa gtgcagaaaa atactctcat cgctttttaa
    13321 agaaaataga caaaaacgcc cagacacgca aatgtctggg cgtttatttt ttagtatagg
    13381 ttaattaagc tttagtaacg tttgttgctt gaggtccgcg ttggccttct tcaacatcga
    13441 aagttactgc ttggccttct tctaaagttt tgaatccgtc gccttggata gctgagaaat
    13501 gaacgaatac atcgtttccg ttttctgcag tgatgaatcc aaatcctttt tctgagttaa
    13561 accattttac tgtacctgtt tccataataa aaatcctcct tgtgtatcaa cacatatttt
    13621 gcaattactt gaatggtgta tatctggaag atgtttattt gaaacaagct accacagatt
    13681 accgaacaaa aactactcct atagtatatc ataccgttta caaaaaagct agagtttttc
    13741 gacttttttt attaaaaaaa gttttctcag cgattacata aagtgaaaaa ccgaactttt
    13801 ttttaaaata aacgacatat tgttcagttg gtgttttttt gctctgatgt tcttttttaa
    13861 actaaaaaaa ttattctttc tgactactta tcggttctgt ttcaacggtc gaggctgggg
    13921 aagattcttt agtaggtctg atgttctcat ggtatttctg atagcctatg acagttacca
    13981 gaagaacaag gcaaaccaat acgaccaacg agattagttt ttcttttttg ctcatatcta
    14041 tacctcataa ataacaggat gatgtccatc atatttctga gtatgagtaa aagcaaaagc
    14101 tgcagctgta gaatgtaaga aatgccagca actttcataa tcacaggtcg gacagtacca
    14161 aaagtaacca aatcttggct gcaaagaccg ttcttctgtt tcaggaatcg cagaatcaag
    14221 atctggtgtc tgtacataaa catttttgta cagacgtgtg cctgtaatag gaaaccgctg
    14281 tgtttcttca gcaaaaactg gctgacttgt taaacttagg gatagagaca gcaaacacca
    14341 taacagtctt tttttcataa agacctcctt atcgataagt ttttcccaat taaaatcata
    14401 tctcaagaac gcccgttatt cacattttgt tcataaatga tgttttttgt atcataatcg
    14461 tcaaaaagag gtcgtgacca cgtcacaacc tcttttttaa acggtgttcc agaagtagct
    14521 tcttcggaaa taagccgaaa tttcacaaaa atttgagaaa taatttttgt caatctcttc
    14581 ttatttcttg aagctgacca cttctgtcac aacctcttcc ttaaacggtg ttcaaaagct
    14641 tgcatctgcg gtaataagcc caccaaacaa aaaatatgaa gagctatttt tgcttgctgt
    14701 tcttattact tgatgcagaa cagctttttc acaacctctc atacacggtg tttaatcagc
    14761 tgaccttcgg tattagctca aaaaacggca aaatatgtga aactattttt ccgtttgttt
    14821 ctctaatact caggtcaaaa cactgatttc acaacctctt ttaataacga agaatcgctg
    14881 tcagactctt ttcatctggc gcatcttttt gatccaaaat aaacactttt ccgccattaa
    14941 tgatcacatc atctgctaat gcattcaaca cttgacgccg atcatattct gtttcaggat
    15001 cttcaccgaa accatcagct aagtttgacg tagcgataaa taaatgtgac acttttcctt
    15061 ctttcgcagc tggaacgata tcaactaact gatcgatgaa tttcttatct aagagtttat
    15121 tgtattcttt tgattcttga gctgcgagtt cacttgacag cttcttcgcc ccttcttcga
    15181 tatctctaaa ggatagctgc gcaggagaag cagaaatcgc aacgtctgca caataatagg
    15241 gatttttagc aatttttttg aacatcgtct gattttctgg tagagcaaat aaataaatcg
    15301 gccattgttc tggattttcg aaagaatcct tcaagtacgt atcaactgct tggtaatagt
    15361 tgacccaatc gatctctact tcttcatctt ttggatttac gccatggaaa gttactccat
    15421 ctcgggctcc gcctcctcca ttagaagaga agttcaaacc gccacctgtc agttcagatc
    15481 ccaatgcagt aacgacatca accggtgccc cttctggtag agatacttct tttacttgtt
    15541 tgttgctgac ttcatacaat ttcatggagt cgcggttcaa tcccaataaa taataagaat
    15601 agttgaactg cccatttttg ataatagcca gtaaataagg aagatcactt acatagtatt
    15661 gatcgtctac cgggatactc aaacgatgga tataggtttg gtcagcagtt ataatgaccg
    15721 ctacactcgt agttgcacta cgccaaaacg aaggatctcc taacaaattt tcaatttttt
    15781 cttggaacgg ggaccagtca tgttcggaat attttttctc aaaacgtttc tttgcttctt
    15841 tcgcaaaatt tttgaatttg atctgatctt tttccacatc ttgatgggcg acatgcgtat
    15901 tcagcatgat cgtgacgaat ggtcctttag cgccttctga agtcaattgt gacaataatt
    15961 ctttatcctt ttttgccata aacgtacccc tcctaaaaaa atcattcctt tgtttctatc
    16021 taaagtctac cacaacacta tttttccata caataaaacg tatctaaaaa aataaaacgg
    16081 tttctacggt tttaaattta gctatttttt taagttatct tcataatttc ctcaattatt
    16141 tagccccagt cttcaactat tcttcatgaa atgctgataa actaagaaaa agaataaaag
    16201 aggtggatct tatgcatttg attatgattt tcagtttatt aagtattatc agtttatttg
    16261 ctttcagcgc ttcccgctta ttagatgcgg aaacacagcc tattcctgta aaagtacgta
    16321 aaaacgaccg ctaaccttcc ataacgtgcg ttcttatcct aaagtttttt cagaaacatt
    16381 gaaactctct cccctctctg ataaaatttt aatttgtagc gaaacaaatt aattacaagg
    16441 agatcggata tgtccataaa aaaaacacgt ctagtcctat tattggctag tctcattctt
    16501 tgccttgctt cttttctacc agctgttgct gtgcaagctg aagatacttt caaagtaaat
    16561 gcaaaagcag cctttgctgt agatgcgcaa agcggtaaga ttctttatga tcaagatgga
    16621 gaaaaaacca tggggatcgc ttcaatcaca aaaatcatcg gtctttacat cgtccttgat
    16681 caagtaaaag aagggaaact atcatgggat gataaagttt caatttcaga ttatgcagaa
    16741 aatttgagtg tcaccccaga tttatcaaat gttcctttgc ataaagaaaa cacctacacc
    16801 gttaaagaat tattcgactc tgcaatcatc cagtcagcca acgcttcaat ggttgccttg
    16861 gcagaaaaaa tctctggcag cgaagcaaaa ttcactgaac gaatgaaaga acaattgaaa
    16921 gattggggta tcaaagatgc aacgatcgtt aatgcatcag gactgaataa ctcttatctt
    16981 ggcgaaaacc gaccagaagg tactggagaa aacgacgaaa atcaaatgtc tgctcaagat
    17041 gtggctatcg ttgcccgtca tttgatcttg gattttccag aaatactgga tgtatctagc
    17101 actacgacac aaatgtttgg cgaaaacacg caatcaccag tagaaatggt caactggaac
    17161 tggatgctcc caggattcgt gaattataaa gaaggcgtgg acggattaaa aactggtacg
    17221 actgaacttg caggagcctg tttcgtcggt acgatcacta aaaacgatca acgaatcatc
    17281 actgtcgtat tgaatgcaga cggccatgcg gaaaacccaa gtgcccgttt caatgaaaca
    17341 gctcgcttaa tggattattg ctacgacaat tggtcagaaa aagagcttgg aaaagccaat
    17401 gcaagtatcc ctagtctaaa aaccattgat gtaaaagacg gaaaagaatc aacagtgccc
    17461 gttgtgctta aaagtcctgt aaaagtatgg gtacggaacg atatggatac tggaaaatta
    17521 acaatcacac caactcttga caaaaaacaa gtcactgaca atgagatcca agcacctatg
    17581 gataaaggaa caaaaatcgg taccgcaacg atcaccttgg cagaagataa attaggttat
    17641 cttgaagaca acaacgcgcc atccacagaa atcatcacgg ataaaaccgt agaaaaagca
    17701 aatattttcg ttattggctg gcgacgcgtc gcagaatttt tcggtaactt gttttaattg
    17761 aacaaaaaga aaaaagcatc tttccatgtg gaagatgttt ttttgctttt tctagtttaa
    17821 ataacagctt ttttcatcta ttttcgttat actgtataag aaaaaggagt tgaatttatg
    17881 aatctaacca gagatctgat ttttttggtt ctctatctta ttggggtatt ctccatcgtt
    17941 tattggcgaa aacagaaaaa ggatccttcc ttgttctttt acagcagtac atggacgttt
    18001 gcggtaatct tgacttattt tgtcgtgttg gaaatttttt attcgacctt ttattttttg
    18061 attcccttag tgtttttcag tatctttgcc ttttcctatt tttcagaaaa gcgaaggctg
    18121 ttgaatggtc ttttattcaa tattttcctc attagttttg gtatctactt gtttgtcttg
    18181 ctatacgaaa cacaaaatat ttttcttggc ggactgattg ccttgatcac gatcccgtta
    18241 ctgcttgtct ttctattcgg catttatgga ttgatcgttt ttcttttttg gaacggtgtc
    18301 acagttttac gtagagagtc gcattcatta gctaatcttt taacgttgat actagccatt
    18361 tttcttacat tgtttcttgt ttttgacttt ttcttgttaa aatatttacc acaatggata
    18421 aatgctttgt ttttctgcat cccattgatc ttgatctatc tatttatcgt attctacaac
    18481 tttttgactg tctcattctt gtatcagttc aaccgccctc gatacaacca agacttcatc
    18541 gttgtgttag gcgccgggtt gatcaatgga gaaacagttt ctcctcttct tgccaagcga
    18601 atcaataagg cgattgcttt ttattgggca caaagccgtg cgacattaaa tccgcctatc
    18661 ctattaatgt cgggtggaca gggagcagac gaaaaagtac cagaagcaat ggcgatgaaa
    18721 caatatgcca tggaacaagg aattcctgaa agagatattc ttgtcgaaac caattcgaca
    18781 accactttgg agaatatgcg ctattcaaag gaaatcatgg atcagcaaat gaaaggtccc
    18841 tatcgcgcga tcttcagttc caacaattac cacattttca gagctggtct ctatgcacga
    18901 caagcgaaac tgaaggcaaa tggcattggg gcaaaaacag ctttctatta cttgcctaac
    18961 gcgtttttaa gagaatacat cgccatcttg atgatgaaca aaaaaagaca tatgatcatt
    19021 tgcggattgc ttttcgcagg ttccgcattc ttatcactga tcactttact tttctaaaaa
    19081 aacaaggtgt gacaaaacat atgtcacacc ttgttttttt cttttattct cttgacgatt
    19141 ggcaagaata gtattccttt tttgacggct acttgctgtg cagaataaat accgctgttt
    19201 cctgaacaca taaagctgat caagcagatc ataaagaagt aagcagcagc ttgtgaacca
    19261 aataattcga ttcccatcac aaaacaggca atcggtgtat ttgtcgcacc agaaaatacc
    19321 ccgataaaac ctaatccagc aagaaaagga acagaaacat ggagcaaagg cgctagtact
    19381 gcgccaagcg ttgcaccaat ctcaaatagt ggtgtcactt ctcccccttg gtaccccgca
    19441 cctaaagaca agaccgtgaa gaataatttc ccaataaaat cataagcatg tgcctgtcca
    19501 ttaaatgatt cctgcagtaa cggaagactc aacccaaggt aacgttgtgt ttgcaaaatc
    19561 aacgctgcgg ctacaactac tgctccacct atcgtatttc gccaaacagg atgaggaatc
    19621 cattgcgcat accgcgcttt taaaaagacg atcgaacggc tgaataccca accaatcaaa
    19681 ccaaaagcaa tcccagcaac aaaaactttg aagaacagca acatactcca ttcaggaatc
    19741 acacccattt ggtaatgtag atgagaaaca ccatagcttt ctgtcatgaa atttgcaaaa
    19801 agcgcagcaa agaagctagg aaatattgct tctgttcgga ctttaccgat tgccaacact
    19861 tctaatccaa ataatgttcc agctaaaggt gtgccaaata cagaactaaa acccgcactg
    19921 attccactga taaccaaaat ctcccgttct gctttatcca atcggaataa atgcgctata
    19981 ttatcagcta atgctccccc catttgaact gctgttcctt cacgaccaac agatccccca
    20041 aataaatggg tagtgatggt cccaaacaag gtcaatggaa tgagccgcaa agggatcttc
    20101 tcttctcctc cattcccttg atcgatcact aagttattcc cacgactaga aagaccgcca
    20161 tgatacgcat aaagataagc aaaaagcgcg ccgctgactg gcaatagata aagtagccaa
    20221 ggatgtgcta gtcggatatc tgtcacgaac gtcaggctat ttaagaaaaa agcagacaag
    20281 ctccccatga atactccgag aatcgctgtg accaccagcc acttcaacat gtacatcaaa
    20341 atacgcactg gactcggtaa ttgtttttcc ataaaaaatt cctcctcaaa taaaaaaacg
    20401 cctactaaag aaaggggctg gccccagact ttagtaggcg tcattagcta tcttacgtta
    20461 gcatttaaag gcgaacacca tcacctattc acttccatta aaagatagca tatttttctg
    20521 taaaaaacaa taaaattatc gttatttctt tacacgttca gcaaattcat agaaaggagc
    20581 caatttcgtt aactgttgat tacattgatc actatcatga caaatataat tccccttttt
    20641 cgtatacgtg ccatcagaac cggctttcgt tgtagaaaga aagagcgaga cattcgatgt
    20701 tttctgacag atcgcacaga ttcccttatt aatcgttggt gataaagtac cgctgatccc
    20761 ttttaatttt ccatcttcgt aataaaccat gaattttttt tgcgtccctg gatcattcca
    20821 accgatgtac gtatgtgctt gcaagtcgat ttcattccaa gcgggttgtt tgagtttttt
    20881 cacttttcgg aataatttct cgatttgtgg tttgctcggc tgcataaacg gctggacgat
    20941 ttgcttcagc tcctccaatg ctcgttctgc ttgcgttttt gtcagtttta catctaaaac
    21001 tgtcgttaaa aacgtatcga tttctgatgg ttcgtaacct aatacatcgc gaatcttttc
    21061 agctgctaga gcctgaaccg tttgtaccgt ttttgagtca ttgacagatg agtacgcatt
    21121 taataactgc tctacttctc tttttataaa aaaatattga tatggtttca ttgtttgttc
    21181 catgatttta aagtcctttc ttctaaccaa agtgcatact ttgtagaaaa aagtgatctt
    21241 ctgcaaagta tgtgttacct gaagatcccg gactctttta aataagatac gttttgcatc
    21301 ttatcatcac cccctttaat gttcattctt ctatgtacat gattcattcg ataaataaaa
    21361 gtaaaccgta tcttgagcag atagtcaact gcaaacagaa aaaggactgt gacaaaagtc
    21421 gtgtcaaagt ccctttctac aaacaaacgg tgttccagaa gtagcttctt caaaaaataa
    21481 gccggaattt cacaaaaatt tgagaagcaa ttttcgtaaa ttccttctta tttcttgaag
    21541 ctgacccact tctgtcacaa cctcaatatg gtctattatt ggttttacct gttaaatcga
    21601 ggattctttt ccgaagtaac gttgccatct cttacgcata cttgctgaca taggctgagc
    21661 ggcttctttg actgcgcagt atttgtctac gaatgttacg atatatcctt ctttgtactt
    21721 aggcggtgca atcgttgcgc cccacatgtg cttcaaaatg atatctcgct caagatccga
    21781 caaatcggtg atcttttctg cattctttac agcgattctt ggatggatat acgcatgtgt
    21841 gccttcatca aatttcgtcg tacgccaatc atagtagaac agatcatgca aaagtccagc
    21901 acgcgctgtt gctttagcat tgccacccca tttttttgcg agcagataac tatagtaaga
    21961 aacactgatg gaatgctcca aacgagtgga atgaacatgc tgtgtgtaat tcgctaattt
    22021 tttcactgct tctgtttcta aaagatcttc tacataagac atatattctt cgtcttcacg
    22081 ccatttttct gtcataatta tcgatctgcc acctttttga atttcatttt cttctgaaat
    22141 tgatctaagt ataccaccag tgttcggatt attctagtcg ccttggataa aatagccaaa
    22201 gcttaatagt tccttaatca taaagaaaaa tgataaagaa caatccctgc cgcaacccca
    22261 acattcaacg attccgcatt tcctttcatc gggatatata cgttctgatc agtcaaagac
    22321 aagatttcct gacttacccc ctgaccttcg ttccccatga ttattgcgaa gttatctgat
    22381 ttttctactt tgtctaaggc gtgtgcttct tcatttaatt ctgtgccata cactgtaaac
    22441 cctttgtctt tcattaaagg aatcacttct gtcaaatctt tttgcaacac aggcaaatga
    22501 taattgcttc cctgcatgct gcgcagcacc tttgtactat aaatatctgc cgttcctttg
    22561 cctaataaaa caccagccat atcaaatgca tctgccgtac ggatcatcgt ccctacattt
    22621 ccaggatctt gtacattatc taataacagc catcctcctg aaaaatctgg cgtgccttca
    22681 gccgttaacg ccatcactgc taagattcct tgtggtgtag gtagatccga tacagcatcc
    22741 atgacctcat ccgaaactag aaaagtagaa atctctttgt ttgcggccag ccagtctccc
    22801 cattctttca tgcctcgctg tgtcacaaaa agttctttta tttctgcatc agacgacgca
    22861 gcttcttcaa tcagatggaa cccttccaaa agatattctt ccttttcttc ccgatatttc
    22921 tttttatgta gtttttttaa ttctttgatt cttggatttt ttgctgattg gatctctttc
    22981 acattcctca cctccccatg attatatcat ggaataggtg cttgagcttg tttcatccta
    23041 aaaaaatcgg tatcattaat ttataaaata ggaaagaaag gtgacgaaca tgcgcaaagt
    23101 taaaatgaac gtccaaggac gcgtccaagg cgtaggattt cgctacatga ccaagatggt
    23161 cgctgatcaa ctaggcgtga ctggaacggt aaaaaacgaa gatgacggct cagtcacgat
    23221 cgaagcaatc ggcaatgacg acatcatcca gaaatttatt gaagaagtca agaaatctcc
    23281 gagcccaagt ggacgagtgc agtatgtgga tgtccaagaa gacccgatga ttgaggaacg
    23341 aaagaaattt gatgtggtgg gataaggttg tgaaaaagct ggtctgcatc aagcattaag
    23401 gacaggttgt gaaaaatagc tctccatatt tttcaacagg ctggacttaa tgccgtagat
    23461 gcaagctttt gaacaccgtc aataaggttg tgagaaagtc gcttagtttt gagtagtaag
    23521 gagaattttg tgaaaatggc tttccacatt tttgcataaa atttgactta ataccgagaa
    23581 actgactttt gaacaccgtc gataaggttg tttttgagac gctttgcctc aagtattaaa
    23641 gataggtagt aaaaaagctg atctataact tgcaataaat ttgcttaacc catattttcc
    23701 agacagaaca aaaaagtttt tagtttttta aataagaaag aaacacttgg aatcactctt
    23761 ttctttccaa gtatttc
//
LOCUS       DAMEEU010000048        23125 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.049, whole genome shotgun sequence.
ACCESSION   DAMEEU010000048 DAMEEU010000000
VERSION     DAMEEU010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23125
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.049"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            15..284
                     /locus_tag="PB779_001807"
     CDS             15..284
                     /locus_tag="PB779_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739329.1"
                     /translation="MKIDYLELINEIAKYKTGEEIEILRDVYDQLEEAGIEGINNDRS
                     SWSKLRYYFALYIDTTQLRNLAYTKLLFVDCVKGLQKHLSELEQV"
     gene            289..453
                     /locus_tag="PB779_001808"
     CDS             289..453
                     /locus_tag="PB779_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739330.1"
                     /translation="MDLKTFTAQIELMHQEALRQSASYEDKWLNTFHGGRESALDQVL
                     KLLKGERRDG"
     gene            446..745
                     /locus_tag="PB779_001809"
     CDS             446..745
                     /locus_tag="PB779_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739331.1"
                     /translation="MDKKAAMKRIIELTHSENWQEDKEIVTEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAEQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEER"
     gene            745..1062
                     /locus_tag="PB779_001810"
     CDS             745..1062
                     /locus_tag="PB779_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1140 family protein"
                     /protein_id="HDE0739332.1"
                     /translation="MDLITQYSDIILKKIMMKIQKDKKSKERAELVKLEMAETGAGVR
                     SSRHWKAAANIEFYYNEIQKGFDQMRELDRQTNWSKKLHQDRFKFVEKYKEILDEYME
                     DRE"
     gene            1059..1232
                     /locus_tag="PB779_001811"
     CDS             1059..1232
                     /locus_tag="PB779_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739333.1"
                     /translation="MMMPKEIYSDALRGARNQLKMAKRTYEIRPTIENERRVKAIRRR
                     CSIYGELQKEDSK"
     gene            1229..1642
                     /locus_tag="PB779_001812"
     CDS             1229..1642
                     /locus_tag="PB779_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739334.1"
                     /translation="MIPRFRAWNKKTQSFIDYGDLVLDLRSGKIYAGDIGLVESTIDV
                     TDQIELMQSTGLKDKNGIEIFEWDIVSVSVRNGFDYLDNKVCVVKNSIGHSGLVCATV
                     DEDLEYQIFNTELFEEYTYEVIGNIWENSELLEVE"
     gene            1639..1977
                     /locus_tag="PB779_001813"
     CDS             1639..1977
                     /locus_tag="PB779_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739335.1"
                     /translation="MIILATDYIDSLKDENGNVPALLNCGIKSKNRIILLRISADLAK
                     YLYLSKTAVYYTAATRYQYKGKTISQDYYDRLISPDMHGKSKSAIKLFGAIEIYADDF
                     PNLWLKEEAE"
     gene            1978..2199
                     /locus_tag="PB779_001814"
     CDS             1978..2199
                     /locus_tag="PB779_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739336.1"
                     /translation="MFKIAFYLFDYKDDSFKKVYFHHWNDSKPVFTKNKRRAQEYFDE
                     RSANKDIVQLKKAESPSAKTLSIRLEEKE"
     gene            2196..2501
                     /locus_tag="PB779_001815"
     CDS             2196..2501
                     /locus_tag="PB779_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739337.1"
                     /translation="MNIKVYLKRNLARFPRSWDTNSYPFEVEEESYLMSANMIEITRD
                     DADEFDKKRSCYFVPNPMYTAVIEDYHISDRFILIDLERPKKRVKQYRRCGFSTKKW"
     gene            2525..2728
                     /locus_tag="PB779_001816"
     CDS             2525..2728
                     /locus_tag="PB779_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HDE0739338.1"
                     /translation="MNTRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQCVAD
                     ASETIRKFGISILNDDRKWEEMR"
     gene            2725..3021
                     /locus_tag="PB779_001817"
     CDS             2725..3021
                     /locus_tag="PB779_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739339.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKARKKPKFKVGDMVRCEA
                     EGFIYPFRGYVEHLYNHSAIIRIENTMECDKRLAKSKENLAVARLVDMEVIKSK"
     gene            3099..3515
                     /locus_tag="PB779_001818"
     CDS             3099..3515
                     /locus_tag="PB779_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HDE0739340.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILAALMALSLISRQILYYSFCDVNKHSNYEI
                     GQLIRGYGEKNVEKLKSIALIEFAEAYKKGVLVQYR"
     gene            4072..4239
                     /locus_tag="PB779_001819"
     CDS             4072..4239
                     /locus_tag="PB779_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739341.1"
                     /translation="MYRPQYLEQKHEVITVQNGNGEIVRKYRRPIKSDTYKRKESNEV
                     IPLYGKRIAKY"
     gene            4265..4609
                     /locus_tag="PB779_001820"
     CDS             4265..4609
                     /locus_tag="PB779_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDE0739342.1"
                     /translation="MTEEFYRWLLQLIREDRLVKFYQSPKWRRLREKAMKRDHYECQE
                     CRRLGKYHRVENVHHIKEVKDRPDLALDLDNLICLCVEHHNEVHGRYLTALDKQEKKI
                     ESFANFDASERW"
     gene            4614..4895
                     /locus_tag="PB779_001821"
     CDS             4614..4895
                     /locus_tag="PB779_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739343.1"
                     /translation="MIINDNGREYDTEKIEEYSSYTQGLIKRLIYVRYVGIRDLLSDN
                     CCSKYKVNQVREALNKDNNVERIKNVFGYSIEEINYYIDFAEAFIPMVR"
     gene            4998..5312
                     /locus_tag="PB779_001822"
     CDS             4998..5312
                     /locus_tag="PB779_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HDE0739344.1"
                     /translation="MFKNELSQNRYREKLRRSLISQLESQKTNIEPFLDNVDRYISLW
                     ETAISLEEDISENGIRLENGKKNESVALLVSVNKQMGLMLDKLAITPELVGEANESIP
                     EL"
     gene            5290..6984
                     /locus_tag="PB779_001823"
     CDS             5290..6984
                     /locus_tag="PB779_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDE0739345.1"
                     /translation="MNQFLSYKHIENWFKAIEEGTIKVCKEQLLLKNYLEERVFTRED
                     IYFDKQMVEDSINIPAQYFPFELIPWEKFLQCFIYGVRWKKDKTLVFNRYLSLMGRGN
                     GKTGFASWNNFFLLTAKHGIKNYDIDIYANNESQAKTSFDDVFKVIKDHPDLDKKVFK
                     ATKEVIQNIATNSKLRYNTANARTKDGKRPGANRFDEIHENEDYSMINVATSGGGKIR
                     DYREFYDTTNGHVRGGPLDDIIEESKMILSGELGIDKDGAEFSSLFPFICRLDNDNEV
                     DDPDMWEKACPTINYNADLKRKMFQEYSQMQRNAGLRLTFMTKRMNRPMEDTRFAVAS
                     YDDVLHTKEKEFPEKMDEVIGTVDFADRRDFASVGLLGKYDKDVYFTQHTFIHESALR
                     LQNIKREVIDISIDQGKSQIVHGKNIEADYIVGWFLEMSNKYYIKKIAMDMYRAKILK
                     PALEEAGFTVEIVRSGSVTHGMLKDLVDDLFINQRLFFGDDAIMRWYCMNVYEEHISN
                     GNIRYEKIEPETRKTDGFFSFLHGLNFLDDIYDSAPVTVTNSSVENTGTGFTPLVF"
     gene            7004..8182
                     /locus_tag="PB779_001824"
     CDS             7004..8182
                     /locus_tag="PB779_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDE0739346.1"
                     /translation="MGIFQKAVGYFTKKATVSLEEYFCKLQVDFVYRKFAIETCIDLI
                     ANAMSKAEFKSYEDGKNKKNDLYYRLNVAPNKKNNATEFRKKLIRRLIFYNEVLIVSP
                     SNNSSEIFIADSWDVTEYALKDDVFSQVQINNIVLDREFLESDVIYIKYADQQIRQLV
                     DAYYQAYGKLISSAMNVYKRSNARRYVLKGNLFRPQDNTTQDQINKMMTSQFKAFMEA
                     DNAGAVFQLQNEYTLEDFSGNFQSNSRDIKNLIDDIFEMTAAAFHVPKNLLKGDMSGL
                     SDQVDAFLMFEIIPIAELIQDAFNASLYEVEEYLSGNFVRVDTTMIKITSFKDLVDAI
                     DVGIRNGVFTINEGRERVGNDRSDKAMADEIFITKNNQQVSKGGEANDDNENISSSKE
                     "
     gene            8145..8831
                     /locus_tag="PB779_001825"
     CDS             8145..8831
                     /locus_tag="PB779_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HDE0739347.1"
                     /translation="MTTMKTFLAVKNEGAVPQIFIQGFIGSSWFFEGNTDKGIKNILD
                     SLGDQEEIEVVINSNGGDVFQGIAIGNLLKSNKAKVNVVINGLAASAASIIAMAGDTI
                     KIYNNAQLMIHRASTYGEGNVDDFRTIADQLESIDKSVKASYKTRFNGTDEALQELLE
                     KESFMDAETALSYGLVDEIIDAENSSGTEAKKEQSVEEILNDVKEKRAEKIAAFTAAL
                     NKTFGQGDVK"
     gene            8831..9991
                     /locus_tag="PB779_001826"
     CDS             8831..9991
                     /locus_tag="PB779_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDE0739348.1"
                     /translation="MTVKNLKGVTAASDQLMKAFKDGNEESFSAAMVSLSKEIQDKIL
                     EEATAKNQDQLVLMNRGQRVLTTQETKFYNEVVKNEGFAGVEELVPATVFERVFEDLE
                     QSHPLLQKITFVNTTGVTEWIVSRGVNPAWWGKLCEAVKKVLDNGFDVINMKQFKLSG
                     YIPVCKAMLDLGPVWLDRYVRTVLVESLRIALEQAIVDGTGKDMPVGMMRDMSKQTSG
                     EYAEKKAEPITALDAVTMGGLMARLSKFNIEGVNDPIYRNVNPSDVVLIVNPTDYWSK
                     VFPAKTVLTANGEYVQVLPVPVSDLQSTAVPEGKAVIGVASDYFMGVGSTLKIEASDE
                     YHFVEDERIYLAKQYANGQPKRNDSFIVLDISALGTTTTTTKPTTTTTTTQA"
     gene            10001..10876
                     /locus_tag="PB779_001827"
     CDS             10001..10876
                     /locus_tag="PB779_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739349.1"
                     /translation="MKYILCQPAINRFKWELEVCLTNLKKLGIKDIVLLFSRHDDQIP
                     IFFEKEYGVEVHVYDDLRDDKEYIPSIKPYLWWKYLEEDHSREDDRYFYIDSDVIFNK
                     RINLRKLPSKDDVWYCSDCCSYLSLDYIRSCENGENILKDMANIVNVTVESLETINTN
                     SGGAQWVINRPKANYWKKVYLDSNRLYRYLRGQKTNIKIWTAEMWAQLWNMMYFNIGP
                     KVHEELDFCFATDPIEKVKEVKILHNAGVTTNDEDLFFKGRYVTSTPFDEDLSFVNKK
                     KCSYAYVKAIKAVVR"
     gene            10873..11184
                     /locus_tag="PB779_001828"
     CDS             10873..11184
                     /locus_tag="PB779_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739350.1"
                     /translation="MTPEQVTEELLIAVKDNIYVTWNEEDESIKKMIAKNAVYLQSKV
                     STTLSFSPESLEYGLLIERCRYDWNRALDEFEQNFASELLGFIQHYALQEYIAGDVNG
                     E"
     gene            11174..11527
                     /locus_tag="PB779_001829"
     CDS             11174..11527
                     /locus_tag="PB779_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDE0739351.1"
                     /translation="MANNRRLEETFNDGWLKILTQTTKRNELGKKIGVEDTEITSLKF
                     RNLSMRDSDITAMDAMGSKLTKKVKTPFHPIAKKFNKDQYFIVIDSMRYNVIYADYDN
                     FYIYFYLESVGEYGD"
     gene            11517..11918
                     /locus_tag="PB779_001830"
     CDS             11517..11918
                     /locus_tag="PB779_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739352.1"
                     /translation="MVIDNSKEKERLNKQISAIKTSLEEHFGLKLFQDSVGEDELPDD
                     FNYFILETGEIEMITEPKYSVGQNLYLTFYSENREDLTGDSLDIISLIQNRSIRFQRM
                     DPNHLKLENQDRYIDQLVFTFRRLLKSDCHG"
     gene            11911..12315
                     /locus_tag="PB779_001831"
     CDS             11911..12315
                     /locus_tag="PB779_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739353.1"
                     /translation="MAKNSWELKINGHDELLVRMERYSSESERLINEALKSKGSAIAV
                     DRITEKIPVSEADLRRGHQHAKNSRPLKTQYINLGFIIRPTRKFEYLKYPDLGIGTSK
                     RNQPDEFMRRGLGLALDPITELLIRQFDKLNK"
     gene            12327..12932
                     /locus_tag="PB779_001832"
     CDS             12327..12932
                     /locus_tag="PB779_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0739354.1"
                     /translation="MAKTTTVTTFDNISIKRISFNFKNATNAISTDCNGQLDGETEMQ
                     RIVKKCGSTEVKSKSKPINMTVTITAHVPMEVYRRFNGLKQDERIKSGIYSYGPDSVG
                     EDFSLAAEIVDDFEEKNKLIGMLACTSNTGLTFSIENGADEVAALELETKVMQDEFGK
                     FYHEAIVAELEEDLTDQWMTNLSADVIKKTSVVTTTATQSQ"
     gene            12952..13314
                     /locus_tag="PB779_001833"
     CDS             12952..13314
                     /locus_tag="PB779_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739355.1"
                     /translation="MNEDYSKIELNDGTILNLEPKLNIKKLLMINRDFNTDEFAKMTV
                     GKGSMDISVIQGAKAVYIAYRQANMTDYISFDEFIDKWDFDMATASYIYQLMMFKQAR
                     DAYQKEFEKANKEKKLQK"
     gene            13317..13499
                     /locus_tag="PB779_001834"
     CDS             13317..13499
                     /locus_tag="PB779_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739356.1"
                     /translation="MPKLLVETWVDVYSMLTDVFSMPSDLVLSDICLDDILQMAYNKS
                     AYEGWKNYAINQSQKN"
     gene            13516..16935
                     /locus_tag="PB779_001835"
     CDS             13516..16935
                     /locus_tag="PB779_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDE0739357.1"
                     /translation="MAKKRTEAEVTFIANDDGLKSTLKEISAELTKNRAELKLEQAQL
                     QQTGSESDKLGSKLSSLEKQYELQSQKVEVTSQRLANAKKYYGENSTEVQKLERELIN
                     QQTAQQRLSNEIDKTSNALAQAKGEIQTYESTMQQLDSEQKNVQASASLIESEYKKWQ
                     ATAGQSASESEKLAKAQEYVSQQSENAEKTIDILRRQLEATQSEFGATSTEAMQMEAK
                     LNDAEREFEELGQAAKNVDTTNLDDIGSKIDMNNLMEASDVLSDIGDKLTELGKQAVD
                     SANSVGSSQSKIQANFGLTKQEAEELTNVARDIYYKGFGESLDQSTDALILVKRNLGD
                     LNNQDLQNITEQAMVLENTMGADMDETLRGVNGLMVNFGLSAQDAMDLMVSGTQNGLD
                     KTHELGDNMAEYSQLWSQMGYSADETFGMLQNGLDAGAYNLDKVNDLVKEMGISLTDG
                     RFEQNMDMFSESTRKAFEEWKNGGGTQKDVINSMIQDFSNMDGQYDQLNKASTIWSAL
                     GEDNAMKVVQSLTDVNHTFDDVSGSAQKMNEDSTTPLQELNGKIAELKDSLAPIGNTI
                     IDALEPVIDFLGKMADAFNNLPQPVQDYAVAIGGLTAAFTLLMPIIVGFMALGGPTTL
                     IIGAVITVIAGVIAIIKNWGAITDWFKGIWSKFTDWLGGTWESIKEGASSVWDGVKET
                     WSGFVDWVQDIWQGVSDWFGELWSGLVEGASNIWQGVQETWQAFVDWVSNIWNGVKEV
                     WSIIWADIVGIVQIPWTLITSLIQAGINIIVGIFDVAGQLLGAAWQAVWTPISDFLKN
                     TWDTMTQWVSIAWNGIVTTFHTIFDPVVAWWNGIWTAISTTASNIWNSISATASSIWN
                     SIKNTITSLVQAAATVIQNIWSTVSSWLGGIWNSISSTASNIWNSVTSSISNAINAAK
                     SAIQSVWNSISSWISGIWNGIKNTALNLWNGITSTISSKVNDGKNAISSGWSNLTGIV
                     SDIFNNVKSTIANIWEGIKKTVSAPIDWIRDKISGIFDNLNISIPHIPLPHFKLSGEF
                     NPLKGKIPTLGVDWYAKGSVFNSPNIIGVGEAGPEAVLPLKRSVLQEIGDRILSSTSV
                     SSRAQTIQPVNNYEFNFTIDGNADEVTMKQTTQQIIDSITKVQNDNASAWR"
     gene            16985..17722
                     /locus_tag="PB779_001836"
     CDS             16985..17722
                     /locus_tag="PB779_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0739358.1"
                     /translation="MTDCIHSIIDGFPDYLHKLALAERPTIPSPKRQRVETSVLGRLG
                     GLVQDYSFEDMSFTLHYNYLEDAEDHQAFKQSFYIMRHWLNYAKKLEFSDDPNVYYVI
                     QTIDIGDAENDIVEWGEFDVNITAKPFARVQEDVPITVDKPQSFSLLNNSLEESFPKI
                     IITPSATSCQFILNDYVFSFEGLVVGTDVVIDSDLMLCYEEQSDGDILDRSNKMKTMQ
                     YPTLQVDINYFNCTGLSKIQIYRNGLR"
     gene            17732..20023
                     /locus_tag="PB779_001837"
     CDS             17732..20023
                     /locus_tag="PB779_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0739359.1"
                     /translation="MIDNLITIYDKNDANNLAEHLYDTQGLGALSDWLTATVSNKLNG
                     AEIFQGTYPISGTNADLIIEGRIIQCYVDENRAKQRLRIYYAKTSVIGNMIEVKAEPI
                     FNDIRKSVLNKYDSGTEKITATQAWQNAKVLAKPAIPSQFSFSSLVDTLANVKIEKAN
                     FLEFFGGKEGSILDRFHGEFLKDNNTLRHETRLGTDHKIKAIYTKNLTGLDLEIDAQS
                     VLVGVYPFISSSSEGEDEITLPEEVIFTDYVEDYPAGYVSFVDFKDKATDVATLREAA
                     KDWLKTNIDKQKPQVSGSIELVPLRHQRGYEKFVDLEKVSMGDGVDVYHPQLKVNMSA
                     RIVEYTFNVLTNSYDKLVVGNVKTNFLENTENNVNNLINDAIDQLKNGGEISDLINDI
                     VDHQTDMITGQDGGYVLLDPKEAPSRILIMDTPDKNTARNVLQINNAGIGFSKTGING
                     TYDTAWTLDGGFNASFITAGEIVGITIRGTTLISDGTDYRTSIANGKMTWYSKKVNKD
                     IMELEARDYVSADAGIVSYTMKTGGGFMIRNPQGNLVFSTWDNGNNKPFLSFGAPNFR
                     YSNASYITDGDGSSLSINGSAGSSWEFKVAGRTMKFTSDGMLTLPGCFFGSWEDGKIA
                     RFEQSTVQVYKNFTVRGTKNSTVPTEHYGQRLLNAYETPEYYFADYGEAVTGDDGKVR
                     VDIDPMFAETVNLSRYMTHVTPTELVLCAVTHEDVDHFIIETSKPNVLVRWNLVAHRL
                     GYEGVRLKEDTAYDSTVLDQKRF"
     gene            20047..22128
                     /locus_tag="PB779_001838"
     CDS             20047..22128
                     /locus_tag="PB779_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739360.1"
                     /translation="MASSLYNLALDFSKELNYTKAIMARQGDKGITVTVKPFLNGLQM
                     DTSGGTFTLKGTTPSNRYVDSVATSITSEEVTFSLDGTFMSEAGYYKHCYVEYRKGNQ
                     ILTTQDIIFFSLGVSDISQGQADEYVSQLEELIRKYNETFDAFMAEIKGRVDSLNQQI
                     TDLTGQAKTLQDKLDALKEEISKLGNLQVMYSNSIDFGGYDYSGKPNLMSKLKSSDFN
                     VGYHGSLTLDNEKLHFTSDGTGSIIMFTRINTPQLTSGKTYTLSAKVRFDEGTTGAID
                     KLRLVYRTSPGEKILLEANSTNITTDDVGKEITIKGTANVNYQITNLDRFYISVSFSN
                     RDKINGGFKLYDIKIEEGSTATPYQPNLLDDPYWVGKTSLGKNIANKGTTFPIKSSAY
                     EIYKGNTEEELIIGQTYTITLKGTKPASQTFVAYNYWNVNFGDLKPVEGLTDVWSLTF
                     TPTKLEPGLPKDLRIFQSPKETAGACRIDWLKIEKGDTRTPNIEQYKYRGIGMRDSNN
                     PKYYVWDLEPSYVENNLATDIKVAEITGKANNYTDGKVSEINSQLTASINEVDTTAKD
                     AQTKANANATAIDELDNKIDERINDTATTTLTVTNGNTGSAKLYREGKTVSIYFVALN
                     GKRSGGNDSTILTIPEGYRPPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYG
                     SDYTFAITYTI"
     gene            22145..22294
                     /locus_tag="PB779_001839"
     CDS             22145..22294
                     /locus_tag="PB779_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739361.1"
                     /translation="MKAAYRPIEPYGFEQIIVNDEEHLPEECTEVEPPIPNWKPKFNY
                     WEGNK"
     gene            22291..22737
                     /locus_tag="PB779_001840"
     CDS             22291..22737
                     /locus_tag="PB779_001840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739362.1"
                     /translation="MKNIWKYGRTGGEYAGKVLDDMLVSVPYTDQPPLEGIRADGEPL
                     TIADQMFDPKLNQWIILANALDHNDLNNLKAMYESLENENGDLKQINAKLMLSDVAIK
                     QENTALKEKADSLAQINSKMMLASLQNSKDISEIKEQLNPASKGGE"
     gene            22739..22876
                     /locus_tag="PB779_001841"
     CDS             22739..22876
                     /locus_tag="PB779_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XkdX family protein"
                     /protein_id="HDE0739363.1"
                     /translation="MFSFSDVKMMYDWGCFTNEQVMVFVPLCITEEKADKIISKEESA
                     S"
     gene            22914..>23125
                     /locus_tag="PB779_001842"
     CDS             22914..>23125
                     /locus_tag="PB779_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739364.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKH"
BASE COUNT         8227 a         3412 c         4965 g         6521 t
ORIGIN      
        1 taagaggtgg aaaattgaaa atcgattatc tagaactaat taatgaaata gcaaagtata
       61 aaactggtga ggaaatagaa atcctgagag acgtatatga tcaactcgaa gaagctggaa
      121 tcgaaggaat taataatgat cgttcgagtt ggagtaaact cagatactat ttcgcactct
      181 atatcgatac aacacaatta agaaatttag cttatacaaa attactattt gttgattgcg
      241 ttaaaggatt gcaaaaacat cttagtgaac ttgagcaggt gtaatcagat ggatctaaaa
      301 acatttacag cacagatcga actaatgcat caagaagctt taagacaaag cgcctcgtac
      361 gaagacaagt ggctcaacac gttccatggt ggacgtgaga gcgcacttga tcaagtactc
      421 aaattattga aaggggaacg tcgggatgga taagaaagcg gcaatgaaac gaatcatcga
      481 actgacacat tctgagaatt ggcaagaaga caaagaaata gttacagaag tccaaaagct
      541 cggtaaatca atgtggactg aaaagcccaa acggagaacg ccgagaaaga ttgcaatttg
      601 gcatggtgat cgaattctag taacaggtac tgctgaacag ttatctgaaa ttactggtct
      661 gagcaaaaac attatttggg atagagctag gagcttatgg attgattcaa aaggacgaca
      721 gtttaggtat gtggaggaga gataatggat ctcattacac aatacagtga catcatcctc
      781 aagaaaatca tgatgaagat tcagaaagac aaaaaatcaa aagaacgagc tgaattagtt
      841 aagttagaaa tggctgaaac aggagcagga gtgcgaagta gcaggcattg gaaagcagca
      901 gcaaacattg aattttatta caacgaaatt caaaaagggt tcgatcagat gcgtgagctg
      961 gatcggcaaa caaattggag caagaaactt catcaagatc gtttcaaatt tgtagagaag
     1021 tataaagaga tattagacga atacatggag gacagagaat gatgatgcca aaagaaatct
     1081 attcagatgc attaagaggt gctagaaatc aattgaaaat ggcaaaaaga acatacgaaa
     1141 ttcggcccac aatcgaaaat gaacgcagag taaaagcaat tcgccgtaga tgttcaattt
     1201 acggcgagtt acagaaggag gacagcaaat gataccgaga tttcgagcgt ggaataagaa
     1261 aactcagtca tttattgatt atggtgattt ggttttagat ttgagaagcg gaaaaattta
     1321 cgctggggac attgggttag tggaaagcac cattgatgtg actgaccaaa ttgaactcat
     1381 gcaatcaaca gggctgaaag ataagaatgg cattgagatt ttcgagtggg atattgtatc
     1441 agtcagcgtg cgaaatggat tcgattattt agataataaa gtttgtgttg tcaaaaattc
     1501 aataggacat tcgggattag tgtgtgccac tgttgatgaa gatttagagt atcaaatttt
     1561 taacacagag ctgtttgaag aatacacgta tgaagtcatc ggaaatattt gggagaatag
     1621 cgagttattg gaggtagagt gattatctta gctactgact acatcgattc tttaaaagat
     1681 gaaaatggga atgtcccagc attgctaaat tgtggaatta aaagcaagaa tagaatcatt
     1741 ttgttacgga tatcggctga tttagcaaaa tatctttatc tgagcaagac agcagtatat
     1801 tacactgcgg ctacacgtta tcagtacaag ggaaaaacaa tcagtcagga ttattatgat
     1861 cgtttaatca gtcctgacat gcatggaaaa tcaaaatcag cgatcaagtt atttggcgca
     1921 atagagatat atgccgatga ttttccaaat ttatggttga aggaggaagc ggaatgaatg
     1981 ttcaaaatag cattttatct gttcgattac aaagatgatt cgtttaagaa agtttatttc
     2041 catcactgga atgatagcaa gccagttttt acaaaaaaca agaggagagc tcaggagtat
     2101 tttgatgaaa gatcagcaaa taaagatata gtgcagttaa aaaaagcaga atcaccatct
     2161 gcgaaaacat tgtcaattcg attggaggaa aaagaatgaa tattaaagtt tatttaaaaa
     2221 gaaatttggc caggtttcct cgaagctggg atacaaattc ctacccattc gaggtagaag
     2281 aagagagcta tctaatgtct gctaacatga tagaaattac aagagatgat gcggatgagt
     2341 ttgataaaaa aagatcatgt tactttgttc cgaatccaat gtatacggct gtaatagaag
     2401 attatcatat atccgacaga tttattctga ttgatctaga aaggcctaag aaacgagtta
     2461 aacagtatag acgttgtgga ttttcaacaa agaaatggtg ataacaaaac agaggtgaag
     2521 aaaaatgaac accagacatc gcagaataac aaaactaaga aaacaggaac tgaatgtact
     2581 aaagacaaag tttgaaaaag aatatggaat ttcagcagaa gaaacatata aagtggcaag
     2641 tcagtgtgtt gctgatgcga gtgagactat tcgtaagttt gggatttcga tattaaatga
     2701 tgatcgtaaa tgggaggaaa tgagatgaaa ctaaaagacg gattttacgc tagtagtcat
     2761 ggtatcggcg gtttaatgct agatatgccg acaaagaacc ctaaagcacg taagaaacca
     2821 aaattcaaag tcggtgacat ggttcgctgc gaagcagaag gattcatcta tccatttcgt
     2881 ggatatgtag agcatctcta taatcactca gcaatcattc gcattgaaaa cacgatggaa
     2941 tgtgacaagc ggttagcgaa aagcaaagag aatttagctg tagcgagatt agttgacatg
     3001 gaagtaatca agagcaaata aaaaaagccg gatcgctccg actgatgtaa taaatccgac
     3061 aagtttatta tatcacataa aaggagcggt ttgacttgat gcaattgtta cgagaggtag
     3121 atttcaaaca gacaagatgt aatgcgagag atgtgctgaa gaactttcgg cgtttggagc
     3181 ggatggcagg tcgctctttg atagatatta agtcgccgat tattacggat atgccgaagg
     3241 cgccgaagca tggcaataag gcagaagacg cgatcattca gatgatggat atagaagcgg
     3301 agagagatgc gattttagcg gctttgatgg ctcttagtct gattagccgt cagatactct
     3361 actacagttt ctgtgacgta aacaagcact ctaattatga aatagggcaa ttgatacgag
     3421 gatacggaga gaagaatgta gagaagctga aatccatcgc attgatcgaa tttgctgaag
     3481 catacaaaaa aggcgtgtta gttcagtatc gttaattttg tagggttttt gtagggatag
     3541 tgtagggttt ttgagcggtt taacgtgata ttatgatagt gtcgaaagat tagtgatagg
     3601 tctaagacaa aataataata aaaggaacat cgttttatta ttgtttcaca attaagcttc
     3661 gatagacagc agcggaaata ttaagaataa ggatgtgaat tttaactcct tctaaattgt
     3721 tcttattatc tatcatcagt tgctgtctat tgtcattatg tcactgtggt ggaaaggtgt
     3781 atcgctcatc taaaatttag gtgcaaactg caaggttcga ttccttgcca gtgactttgg
     3841 taaccgaggc atcggcggtt taaaaatata ggggtgcgca atttcgtacg cgttttgtgc
     3901 atcttgtagg ttgctattac ataattggtt gggttagatt gagttttggg attcggtaca
     3961 aatgaatcgt caaatgactc aagcacagga tcggaaacgt ccctgcctgt gcattacata
     4021 ttagatcact ctttgagtgg tctttttatt ttgcgtaaag gaggcacgac gatgtataga
     4081 ccacaatact tagaacagaa gcatgaagta atcactgtgc aaaacggtaa cggtgagata
     4141 gtacgaaagt atagaagacc aataaagagc gatacatata aacggaagga aagcaatgaa
     4201 gttattccat tgtatggcaa aagaatagct aagtattaaa taagattgcg aaaggagatg
     4261 ggacatgacc gaggaattct atagatggtt attacagttg ataagagaag atcgtttggt
     4321 taagttctat cagtctccta aatggcgcag gcttagagag aaagcgatga aacgagatca
     4381 ctatgaatgc caagagtgta gaagactagg taagtatcat agagtagaga acgttcatca
     4441 tataaaggaa gtcaaggata gacctgactt agctttagat ttagataatc ttatttgttt
     4501 atgtgttgaa catcataatg aagttcatgg cagatatctt acagcgttag ataaacaaga
     4561 gaagaagata gaaagcttcg ctaacttcga tgcaagtgaa aggtggtaag tgcatgatca
     4621 tcaatgacaa tggcagagag tatgatacag aaaagattga agagtattca tcttatactc
     4681 agggattaat taaacgtttg atatacgttc gctatgtagg tattagggat ctgttatcag
     4741 ataactgttg tagtaaatac aaagtgaatc aagtaagaga agcgttgaat aaagataata
     4801 acgtcgaaag aataaaaaat gtttttggat atagtattga agagattaat tattacattg
     4861 acttcgctga agctttcatt ccgatggtga gataaccccc ccttaaaata aatcgcaaat
     4921 tttttggggg tgatgaaacg gagggggctg tcaggaaaag agattttttc gaactttatc
     4981 atgaaaggag ggctaaaatg tttaaaaacg aattgtctca aaatcgctac agagaaaaat
     5041 tacgccgctc tttaataagc caattggaaa gtcagaaaac aaatattgag ccattcttag
     5101 ataatgttga tcgttatatc agtttatggg aaacggcgat atcactggaa gaagatatat
     5161 ccgagaacgg cattagactg gagaatggta aaaagaatga atcagtagcg ttgcttgttt
     5221 ctgtcaacaa acaaatggga ttgatgttgg ataaacttgc cattactcct gaattggtag
     5281 gtgaagcaaa tgaatcaatt cctgagttat aagcatattg aaaattggtt caaagctata
     5341 gaagaaggca ctatcaaggt atgcaaagag caattattgc taaaaaatta tctagaagaa
     5401 agagtcttta ctagagaaga tatttacttc gataagcaga tggtagagga ttcaatcaat
     5461 ataccagcac aatactttcc attcgaatta attccgtggg aaaaatttct acaatgtttt
     5521 atttatggtg ttcgatggaa aaaagataaa acactagtgt tcaatagata tctttcatta
     5581 atgggacgtg gtaatggtaa aactggtttt gcttcttgga acaacttctt tctactaacc
     5641 gctaaacacg gtattaaaaa ttatgatatt gatatctatg ccaataatga aagccaagca
     5701 aagactagtt ttgatgatgt atttaaagta attaaagatc atcctgattt agataaaaaa
     5761 gtatttaaag ctacgaagga agttattcaa aatatcgcta caaacagcaa acttcgttat
     5821 aacacggcaa atgctagaac aaaagatggg aagcgaccag gtgcaaaccg ctttgatgaa
     5881 attcacgaaa atgaagatta ttcaatgata aatgtggcta cttctggtgg tggtaaaatt
     5941 cgagattata gagaatttta tgatacaact aatggtcatg ttcgtggtgg tccgcttgat
     6001 gacattatag aagaatcaaa aatgattctt tctggagaac ttggaattga caaggatgga
     6061 gcagaatttt ctagtttgtt tccatttatt tgtcgcttgg ataacgataa tgaagttgat
     6121 gatcccgaca tgtgggaaaa agcttgtcca actattaatt acaatgcaga tttaaaacgg
     6181 aaaatgtttc aagaatactc tcaaatgcaa cgtaatgctg gtttaagact tacgttcatg
     6241 accaaacgaa tgaacagacc tatggaagat acacgatttg ctgttgcttc atatgatgat
     6301 gttctgcata cgaaagaaaa agaatttcct gaaaaaatgg atgaagtgat aggaacagtc
     6361 gattttgctg atagacgaga ttttgccagc gttgggttgc taggaaaata cgataaagat
     6421 gtttatttta cacaacatac ttttatccac gaatcagccc ttcgattaca aaacatcaaa
     6481 cgagaggtta tagatatttc tatagatcaa ggaaaatcac agatcgttca tggaaaaaat
     6541 atagaagctg attatattgt aggttggttt cttgaaatga gtaataaata ttatattaaa
     6601 aaaatcgcta tggatatgta ccgtgcaaaa atattgaagc ccgctttaga agaagcaggt
     6661 tttactgtgg aaattgttcg aagcggatct gttacacatg gtatgttaaa agatctggtt
     6721 gatgaccttt ttattaatca acgtttattt tttggtgacg atgcgattat gcgttggtat
     6781 tgcatgaatg tatatgaaga gcatatttct aatggaaata tacgctatga aaaaatagaa
     6841 cctgaaacta gaaaaacgga tggctttttt tcattccttc atggtttgaa ttttttagat
     6901 gatatttatg attctgctcc tgtaacagtc acaaatagct cagtagaaaa tacaggaact
     6961 ggatttactc ctctagtatt ctaacttgaa aggaggtgag aaagtgggga tttttcaaaa
     7021 ggcggtagga tacttcacaa aaaaagcaac ggtttcttta gaagaatact tttgtaaatt
     7081 gcaagttgat tttgtgtatc gaaaatttgc gattgaaact tgtattgatt tgattgcaaa
     7141 tgcgatgagt aaagcggaat tcaagtcata tgaagatgga aaaaataaaa agaatgatct
     7201 ttactatagg ctgaatgtag ctcctaataa gaaaaataat gcaacagaat ttagaaaaaa
     7261 actgatcagg agattaatat tctacaatga agtattgatc gtttctccgt ctaataattc
     7321 tagcgaaata tttattgcgg atagttggga tgtcacagaa tatgcattga aagatgatgt
     7381 gttttctcaa gtgcaaatta acaacatagt ccttgataga gaatttctag aaagtgatgt
     7441 tatctatata aaatacgcag atcaacaaat taggcaacta gtcgatgcgt attatcaagc
     7501 gtatgggaaa ctcatttcta gtgccatgaa tgtttacaag cgctctaacg ctcgtagata
     7561 cgtactgaaa gggaatttat tccgaccgca agacaataca acacaagatc aaatcaataa
     7621 aatgatgaca tcacaattta aggcttttat ggaagctgat aatgcaggtg cggtatttca
     7681 attacaaaat gagtacacat tagaagattt cagcggaaac ttccaaagca attcaagaga
     7741 tataaaaaac ttaatagacg acatctttga gatgacagca gcagcgtttc acgttccgaa
     7801 aaacctacta aagggagaca tgagtgggtt atcggatcaa gtggacgctt ttttaatgtt
     7861 cgaaatcata ccgattgctg aacttattca ggatgcgttt aacgctagtc tctatgaagt
     7921 agaagaatac ttgtcaggga attttgtacg tgtggataca actatgatca agattactag
     7981 cttcaaagat ttggttgacg ctattgatgt aggcattaga aatggagtat ttacaatcaa
     8041 cgaaggaaga gagcgcgttg gaaatgatcg ctctgataag gcgatggcag atgaaatatt
     8101 tataactaaa aacaatcaac aagtatcgaa aggaggtgag gcgaatgacg acaatgaaaa
     8161 catttctagc agtaaagaat gaaggcgcag taccgcaaat ttttattcag ggatttattg
     8221 gttctagttg gttctttgaa gggaatactg acaagggaat caaaaatatt ttggatagtc
     8281 taggtgatca agaagaaatt gaagtagtaa ttaattcaaa cggtggagac gtatttcaag
     8341 ggattgctat tgggaactta cttaagtcaa ataaagcaaa agttaacgtt gtgattaacg
     8401 gcttagccgc tagtgctgct tcaattatcg caatggctgg cgatactata aaaatctaca
     8461 acaatgcaca attgatgatt caccgcgctt ccacatacgg agaaggaaat gtcgatgact
     8521 tccgtacgat tgctgaccaa ctggaatcaa ttgataaatc ggtaaaggct tcatataaaa
     8581 cacgattcaa tggcacagat gaagcattgc aagaacttct tgaaaaagaa tcgtttatgg
     8641 atgcagaaac agctttgagt tatggattgg tcgatgaaat tatcgatgca gaaaatagct
     8701 caggtactga agctaaaaaa gaacaaagcg ttgaagaaat tttgaatgac gttaaagaaa
     8761 aaagagcaga aaaaattgct gcatttacag cagcattaaa taaaacattt ggacaaggag
     8821 atgtaaaata atgacagtta aaaatttaaa aggtgtaaca gctgcaagcg accaattgat
     8881 gaaagctttt aaagatggta acgaagaatc ttttagcgca gctatggtaa gcttatctaa
     8941 ggaaattcag gataaaattt tagaagaagc aacagcaaaa aatcaagatc aattagtatt
     9001 aatgaaccgt ggtcagcgtg tattaactac acaagaaaca aaattctata acgaagtagt
     9061 gaaaaacgaa ggttttgcag gggtcgaaga attagtgcca gctactgtat ttgaacgtgt
     9121 atttgaagat ttagaacaat ctcatccact attgcaaaaa attacttttg ttaacacaac
     9181 tggtgtaaca gaatggattg tgtcacgtgg agtcaatcca gcatggtggg gtaaactttg
     9241 cgaagctgtt aaaaaagttt tagataatgg ctttgatgta attaacatga agcagttcaa
     9301 gctatcaggt tatattcctg tatgtaaggc aatgcttgat ttaggtccag tatggttaga
     9361 tcgttatgtc cgtactgttt tagtagaatc attgagaatt gcattagaac aagcaattgt
     9421 tgatggtact ggtaaagata tgccagtcgg aatgatgcgt gacatgagca aacaaactag
     9481 cggagaatat gctgaaaaaa aagcagaacc tattacagct ttagatgctg taactatggg
     9541 cggtttgatg gcgcgactat caaaattcaa tatcgaaggt gtgaatgatc cgatttatcg
     9601 taatgtgaat ccttctgatg tggtcctaat tgtgaatcca actgattact ggtctaaagt
     9661 attcccagct aagactgtac taactgctaa tggagaatac gtacaagtat tgccagtacc
     9721 agtttcagat ttgcagtcaa cggctgtgcc agaaggaaaa gcagttattg gggtagcctc
     9781 agattacttc atgggtgtag gatctacact aaaaattgaa gcttcagatg aataccattt
     9841 tgttgaagac gaacgcattt atctagctaa acaatatgca aacggtcaac ctaaacgtaa
     9901 cgatagtttc attgtattag atattagcgc tttgggaact actactacaa ctacaaaacc
     9961 aacaaccaca acaactacaa cacaagcgta ggtgatcaga atgaagtata ttctttgtca
    10021 gccggcaatc aatcggttta aatgggagct tgaagtttgt ttaactaatc tgaagaaact
    10081 aggaatcaaa gatatcgtat tgcttttcag cagacacgat gatcagattc ctattttttt
    10141 tgagaaggaa tatggtgttg aagttcatgt gtacgatgat ctgcgggacg acaaagagta
    10201 tattccttcg attaaaccat atttatggtg gaaatattta gaagaagatc attcgcgtga
    10261 ggacgaccga tatttctata tcgattcgga tgtcattttc aataaaagaa ttaatttgcg
    10321 caaattacct tctaaagatg atgtttggta ttgtagcgac tgctgtagtt atctaagtct
    10381 tgattatatt agaagctgtg aaaacggaga aaatattcta aaagatatgg caaacattgt
    10441 aaatgttaca gtagaatctt tggaaactat aaacactaat tcaggaggcg cacagtgggt
    10501 tattaaccgc cctaaagcga attattggaa aaaggtttat ctggattcta atcggctata
    10561 tcgctacctt agagggcaaa aaacaaatat aaaaatctgg acagccgaga tgtgggcaca
    10621 gctttggaac atgatgtatt tcaatattgg tcctaaagtt cacgaggaat tagacttttg
    10681 ttttgctact gatccaatag aaaaagttaa agaagtaaaa atcttacaca atgctggagt
    10741 aacaacaaac gatgaagatt tatttttcaa agggagatac gtgacttcta cgccttttga
    10801 tgaagattta tcatttgtaa acaagaaaaa atgctcttac gcatatgtta aagcaattaa
    10861 ggcggtggtt agatgacgcc tgaacaagtg actgaagaat tgctaatagc tgtgaaggat
    10921 aatatttacg ttacctggaa cgaagaagat gagtcaatta aaaagatgat agctaaaaat
    10981 gctgtttatc ttcaaagtaa agtgagtaca acactttctt tttctcctga aagcttagaa
    11041 tacggattgc taatcgaaag atgtagatac gactggaatc gtgctttaga tgagtttgaa
    11101 caaaatttcg ctagtgagtt attaggtttc attcaacatt atgcgctaca agaatatatt
    11161 gcaggtgatg tgaatggcga ataatcgtag actcgaagaa acattcaacg atggttggtt
    11221 aaagattttg acgcaaacta ccaaaagaaa tgaactagga aaaaagattg gtgtagaaga
    11281 tacagaaatc acttctttaa aatttagaaa tctttccatg agagatagtg atataacagc
    11341 tatggatgcg atgggatcga aattaactaa gaaagtaaag actccatttc atccaatcgc
    11401 caagaaattt aataaagatc aatattttat cgtaatcgat agtatgcgtt acaacgttat
    11461 ctatgccgat tacgataatt tttatatcta tttttatctt gaaagtgtgg gtgaatatgg
    11521 tgattgataa ttctaaagaa aaagaacgtt taaataagca aatttctgct atcaaaactt
    11581 ccttagaaga gcattttggc ctcaaactct ttcaagactc cgtaggcgag gatgagctac
    11641 ctgatgattt taattacttc attctcgaaa caggagaaat agaaatgatc actgagccaa
    11701 aatatagcgt gggtcaaaat ctatatctaa ctttctattc agaaaataga gaagatttaa
    11761 caggagattc actagatatt atttcattga ttcaaaatcg ttcgattcgt tttcagagaa
    11821 tggatcccaa tcatttaaaa ctagagaacc aagatcgcta tatcgatcaa ttggtattta
    11881 cgtttagacg attattgaag agtgattgtc atggctaaaa atagttggga gctaaaaata
    11941 aatggacatg atgaacttct tgtgcggatg gaacgctatt caagcgagag cgaacgactg
    12001 attaacgaag cattgaaatc aaaaggttcg gctattgcag tggataggat tacagaaaaa
    12061 attcctgttt ctgaagcaga tttaagaaga gggcaccaac acgcaaaaaa tagtcgtcca
    12121 cttaagactc aatacattaa tttgggtttc atcattagac ctacaagaaa atttgagtat
    12181 ttaaaatatc ctgatttggg gataggtact tctaaaagaa atcagccgga cgaatttatg
    12241 agaagaggat taggtcttgc acttgatcca attacagaac ttctgattcg tcaattcgat
    12301 aaattaaata aataggagga acaacaatgg ctaaaacaac aacagtaaca acttttgaca
    12361 atataagtat taaaagaatt tcttttaatt ttaagaatgc aacaaatgca atttcaactg
    12421 attgtaatgg acaattagat ggcgaaacag aaatgcagag aattgtaaaa aaatgcggtt
    12481 caacagaagt aaaatcgaaa tctaaaccaa tcaatatgac ggtaacaatt actgcacatg
    12541 taccgatgga agtttatcga cgcttcaatg ggttgaaaca agatgaacgt attaaatcgg
    12601 gaatttactc ttatggtcct gattccgtag gggaagattt ctctcttgct gcagagatcg
    12661 tggatgattt cgaagaaaaa aataagctga ttggtatgtt agcatgcact tcgaatacag
    12721 gattaacatt ctctattgaa aatggtgcgg atgaagtagc tgcgttagaa ctagaaacaa
    12781 aagttatgca agatgaattt ggtaaatttt atcatgaagc aattgttgca gaacttgaag
    12841 aagacttaac agatcaatgg atgacgaatc tatctgctga tgtgattaaa aaaacttcag
    12901 ttgtgacaac tacggccact caatcacagt aaaaaaaacg gaggtagcga aatgaacgaa
    12961 gattactcaa aaattgaact aaacgatgga acaattttga atttagaacc taaactgaat
    13021 atcaagaaat tattgatgat caatagagat tttaacacag acgagtttgc aaaaatgact
    13081 gtgggaaaag gatccatgga tatttctgtt attcaaggtg caaaggctgt gtatattgct
    13141 taccgccaag cgaacatgac tgattatatt tcattcgatg aatttatcga taaatgggat
    13201 tttgatatgg ctactgccag ctatatttat caattgatga tgttcaaaca agcacgcgat
    13261 gcttatcaaa aagaatttga aaaagcaaat aaggaaaaaa agcttcaaaa gtaaaaatgc
    13321 caaagctctt agttgaaacg tgggtcgatg tctattcgat gttgaccgac gttttttcta
    13381 tgccttcaga tttggtttta agcgatatct gtttagatga cattttgcaa atggcttaca
    13441 acaagagtgc ttatgaagga tggaaaaact atgcaataaa ccaatcccag aaaaactaaa
    13501 gaaaggaggt aaaaaatggc taaaaagaga acagaagcag aagtaacatt catagctaac
    13561 gatgacggat tgaaatctac gttaaaagaa atcagtgctg aattaactaa aaatagagca
    13621 gaattaaaac tagaacaagc tcaattacaa cagactggtt ctgaatcaga caagttagga
    13681 agtaaattat cttctttaga aaagcagtat gaattacaaa gtcaaaaagt tgaagtaact
    13741 agccaacgtt tagccaatgc caaaaaatat tatggagaaa attccaccga agttcagaaa
    13801 cttgagagag aactgattaa ccaacaaaca gcgcaacaac gtttgtcaaa cgaaattgat
    13861 aaaacgagta atgcactagc tcaagcaaaa ggcgaaatac agacgtacga gtctacaatg
    13921 caacagttgg atagtgaaca aaaaaatgtt caagctagtg cttctctgat tgaatccgaa
    13981 tacaaaaaat ggcaagcaac tgctggtcaa tcagcttctg aatccgagaa attagcgaaa
    14041 gcccaagaat atgtttctca acaatctgaa aatgcagaga aaacgataga tatcctgaga
    14101 cgacagttag aagctacaca gtctgagttt ggcgctacat ccacagaagc aatgcagatg
    14161 gaggcgaagc ttaatgatgc tgaacgtgaa tttgaagagt taggacaagc tgctaaaaat
    14221 gtagatacaa ctaacttgga cgatatcgga agcaaaatag atatgaataa tctaatggaa
    14281 gcttctgacg ttttaagcga cattggcgat aagcttacag aattagggaa acaagcagtg
    14341 gactctgcta atagtgtagg tagttcccag agtaaaatac aagctaattt tggtttgact
    14401 aaacaagagg ctgaagaatt aacgaatgta gccagagaca tttattataa aggttttgga
    14461 gaatcgttag atcagtccac agatgcattg attttggtaa agcgtaattt aggcgattta
    14521 aataatcaag atttacaaaa tatcacggaa caagctatgg tcctagaaaa caccatgggc
    14581 gctgatatgg atgaaacgtt acgtggtgta aatggcttaa tggtcaattt cggcttgagc
    14641 gctcaagatg caatggattt aatggtttcg ggtactcaaa acggtttaga taaaacgcac
    14701 gaattaggcg acaatatggc agaatatagc caattatgga gtcaaatggg atattcagct
    14761 gatgaaacgt tcggaatgct tcaaaatggt ttagatgcgg gtgcttataa ccttgataaa
    14821 gtcaatgact tagttaagga aatgggaata tcgttaacag atggtcgatt tgagcaaaac
    14881 atggatatgt ttagtgaaag tactagaaaa gcttttgaag agtggaaaaa tggcggagga
    14941 acacaaaaag acgttattaa ttccatgatt caagatttta gcaatatgga tggtcaatac
    15001 gaccaattaa ataaagcttc gacaatttgg tctgcgcttg gcgaagataa cgcgatgaaa
    15061 gttgtccaat ctttaactga tgttaaccat acatttgatg atgttagtgg atctgcacaa
    15121 aaaatgaatg aagattctac tactccgttg caagagttga acgggaaaat agctgaatta
    15181 aaggattcat tagctcctat aggcaacaca atcatagatg cactcgaacc agtaattgat
    15241 tttctaggaa agatggctga tgcgtttaat aatcttccac aaccagtaca ggattatgcc
    15301 gtagcgattg gcggattgac tgctgcattt actttattaa tgccaataat agttggcttc
    15361 atggctctag gtggtcctac tacattaata ataggagcag ttattactgt tattgctgga
    15421 gttatagcaa ttataaaaaa ctggggcgca attactgact ggtttaaggg aatatggagt
    15481 aaattcactg attggttggg tggtacttgg gaaagtataa aagaaggtgc ctcatcagtt
    15541 tgggatggag ttaaagaaac ctggtctgga tttgtagatt gggttcaaga tatttggcaa
    15601 ggagtttctg attggtttgg agagctatgg agcggattag ttgaaggagc ttccaacatc
    15661 tggcaaggag tccaagagac ttggcaagca ttcgttgatt gggtttcaaa tatttggaac
    15721 ggagtcaaag aagtatggtc gattatttgg gcagacattg taggaattgt tcaaatacca
    15781 tggaccttaa taacgtcatt gattcaagcc ggtattaata ttatcgtggg tatttttgat
    15841 gtagctggac agttattagg cgcagcttgg caagctgttt ggacacctat ttctgatttc
    15901 cttaaaaaca cttgggatac tatgacacaa tgggtaagca tcgcttggaa tggaattgta
    15961 actacattcc atactatatt tgatccagta gtggcatggt ggaatggtat atggacagct
    16021 attagtacta cggcttcaaa tatttggaat tcaattagtg caacagcttc tagtatttgg
    16081 aacagtatca agaatacaat cactagcttg gtacaagcag ctgctacagt aattcaaaat
    16141 atttggtcaa ctgtatctag ttggttaggt ggaatttgga attcaatcag ctctacagca
    16201 tcaaatatct ggaatagtgt gactagtagt ataagcaatg ctataaacgc agctaaaagt
    16261 gccattcaaa gtgtttggaa tagtatatct tcgtggatca gcggaatttg gaacggtatc
    16321 aaaaacactg ctttgaatct ttggaatgga attacaagca ctattagctc taaagtaaac
    16381 gatggaaaaa atgcaatttc aagcggttgg tccaatctaa caggtattgt ttccgacata
    16441 ttcaataatg ttaaaagtac aattgctaac atttgggaag gtatcaaaaa gactgttagc
    16501 gctccgattg attggattag agataaaatc agtggtattt ttgataattt gaatatttct
    16561 ataccacata ttccgttacc acattttaaa ttgagtgggg aattcaatcc attgaaggga
    16621 aaaatcccaa cgttgggtgt tgattggtat gcgaaaggta gtgtgtttaa ttctccgaat
    16681 attatcggtg taggtgaagc aggacctgaa gcagttttac cattgaaaag atctgtgctg
    16741 caagaaattg gtgatcgtat cttgagtagc acatcagttt catctagggc acaaacgatt
    16801 caacctgtga acaattacga attcaatttc acaattgatg gtaacgcaga tgaggttact
    16861 atgaagcaaa caactcaaca aatcattgac agcattacaa aagttcaaaa tgataatgct
    16921 tcggcatggc gttaaacagg agagtatttc tcctgttttt tagtattaaa aaggatgtga
    16981 aaaaatgact gattgtatac attctataat cgatggattt cctgattatt tgcataaatt
    17041 ggctttagct gaaagaccaa ccataccatc tccaaaaaga cagagagttg aaacttctgt
    17101 tttaggacgg ttaggtggct tagtacaaga ttattcgttt gaagatatgt cgtttacttt
    17161 gcactataac tatttagagg atgcggaaga ccatcaagcg ttcaagcaat cgttttatat
    17221 catgcgtcat tggttaaact atgcaaagaa attagaattc tctgatgatc ccaacgtcta
    17281 ttatgttatc cagactatcg atattgggga tgcagaaaac gatattgttg aatggggaga
    17341 gttcgatgta aatattactg cgaaaccatt cgcaagagtt caagaagatg tgcctataac
    17401 cgtagataaa ccacagtcat ttagtttgct gaataatagt ttagaagaaa gttttccaaa
    17461 gattatcatc actccttcag ctacttcatg ccagttcatc ttaaatgatt atgtgtttag
    17521 ttttgaaggc ttagtagtag gaactgatgt agtcattgat agtgatttaa tgctttgcta
    17581 cgaagagcaa tcggacggag atattttaga tcgatccaac aaaatgaaga ccatgcaata
    17641 tccgacattg caagtggata ttaattattt taattgtact ggtttgagca aaatacaaat
    17701 ttatcgtaat gggttaaggt aggtgaaata gatgatcgat aatttaataa ctatttacga
    17761 taaaaatgac gcgaataatt tagctgaaca tttatatgat acacaaggtt taggcgcttt
    17821 gtcagactgg ttaacagcca ctgttagcaa taaattaaac ggagccgaga tatttcaggg
    17881 tacttatcca ataagcggaa ctaatgcaga cttgattata gaaggacgta ttattcagtg
    17941 ctatgtggat gaaaatcgag caaagcaacg tttacggatt tattatgcaa agacttctgt
    18001 aataggaaat atgatagaag taaaagctga acctattttc aatgatataa gaaaatcggt
    18061 gttgaataaa tatgacagcg gaacagaaaa gatcactgct actcaggcat ggcaaaacgc
    18121 aaaagtttta gcaaaaccag ctattccttc gcagttttct ttctcatcgt tagtagatac
    18181 gcttgctaat gtgaagatag aaaaggcgaa ttttttagaa ttctttggcg gaaaggaagg
    18241 atctatccta gatcgatttc atggggaatt tcttaaagat aataacacat tacgtcatga
    18301 aacaaggcta ggtacggatc ataaaatcaa agcgatttat actaaaaact taactggtct
    18361 cgacttagag atagatgctc aaagtgtttt agttggagtt tatccattca ttagcagttc
    18421 gtcagaagga gaggatgaga tcactctacc agaagaagtc attttcacgg attacgtgga
    18481 agattatcct gctggatatg tttcttttgt tgattttaaa gacaaagcga ctgatgtggc
    18541 cacattaagg gaagctgcta aagactggtt gaaaacaaac atagataaac agaaaccaca
    18601 agtgagtggt tcgattgaat tagtaccatt gaggcatcaa agaggctatg aaaaatttgt
    18661 tgatctagaa aaagtttcga tgggtgacgg agtagatgtg tatcatccac agttaaaagt
    18721 gaatatgtca gcaagaattg tggaatatac gtttaatgtt ttaaccaatt catacgataa
    18781 attagttgta ggaaacgtca aaacaaactt cttagaaaat acagagaata atgtcaacaa
    18841 tttgattaat gatgccattg atcaattgaa aaatggtggc gaaatcagtg atttaatcaa
    18901 tgatattgta gatcatcaaa ctgacatgat tactggtcaa gatggtgggt atgttttact
    18961 agatcctaaa gaagcaccta gtcgtatttt gattatggac acgccagata agaataccgc
    19021 aaggaatgtt ttacaaatca acaatgctgg tattggtttc tctaaaactg gtattaatgg
    19081 aacgtatgac accgcatgga cgttagatgg cggatttaat gcctcgttta ttacagctgg
    19141 tgagatagta gggattacta ttagaggtac tacattaatt agtgatggta ctgattatag
    19201 aacaagtatt gccaatggca aaatgacttg gtactcaaaa aaagttaaca aagatattat
    19261 ggagctagaa gcacgtgatt atgtaagtgc tgatgccggt attgtatcat acaccatgaa
    19321 aactggtggt ggtttcatga ttagaaatcc acaggggaat ttggttttta gtacgtggga
    19381 taatggcaat aacaaaccgt ttctatcttt tggtgcgccc aatttcaggt atagcaatgc
    19441 tagttatata actgatggcg acggtagttc tttaagcatt aatggtagtg cgggtagttc
    19501 atgggagttt aaagtagctg gcaggactat gaaatttact agtgatggta tgctaacgtt
    19561 gccaggttgt ttttttggtt catgggaaga tgggaaaatt gcaaggtttg aacaatcaac
    19621 ggtacaagta tataaaaatt ttactgttag aggtactaaa aactcaaccg taccgacaga
    19681 acattatgga caacgactat tgaacgctta tgaaactcca gaatattatt tcgctgatta
    19741 tggagaagcc gttacaggtg atgatggtaa agttcgtgtt gatattgatc ccatgtttgc
    19801 tgagacagta aatctaagtc ggtatatgac acatgtgaca cctacagaac tagttttgtg
    19861 tgctgttact catgaagatg ttgaccattt catcattgaa actagtaagc caaacgtatt
    19921 ggttagatgg aatttagtgg cacatcgact agggtatgaa ggtgttagat taaaagagga
    19981 tacagcatat gatagcacag tgcttgacca aaaacgtttt taaaacgaag acaaggaggt
    20041 atataaatgg ctagcagttt atataatttg gctctagatt tcagtaaaga attaaactac
    20101 accaaagcta ttatggctcg tcaaggtgac aaaggaatta cggtgactgt taaaccattt
    20161 ttaaatggct tgcagatgga tacgagtggc ggaacattta ctttaaaagg aacaacgcca
    20221 tctaaccgtt atgtagatag tgttgcaact agtataacta gtgaagaagt cacattttct
    20281 cttgatggca catttatgag tgaagcagga tattataaac actgctacgt agaatataga
    20341 aaaggtaatc aaattttaac aacgcaagac atcatttttt tctcactagg agtgtctgac
    20401 atttcgcaag gccaagctga tgaatacgtt tcgcaattgg aagagttgat tcgaaagtat
    20461 aacgaaactt ttgatgcttt tatggctgaa attaaaggta gagtggatag cttaaatcaa
    20521 cagattactg atttaactgg tcaagctaaa acgctacaag acaagttaga tgctctgaaa
    20581 gaagaaattt ctaagttagg taacttacaa gtgatgtaca gtaacagcat cgacttcggg
    20641 ggatatgatt atagcggtaa gccgaattta atgtccaaac taaaatcgag cgattttaac
    20701 gttggttacc acgggtcact aactttggat aacgaaaagt tacattttac ttctgatggt
    20761 acaggaagca ttattatgtt tacgcgtatt aatacacctc agcttactag tgggaaaacc
    20821 tatactctga gtgcgaaagt tcgatttgat gaaggaacta caggagctat tgataaatta
    20881 cgtttggtgt atcgtacatc accaggagaa aagatattat tggaagcaaa tagtacaaat
    20941 attacaacag atgatgtagg gaaagaaata acaatcaaag gtacagctaa cgttaattat
    21001 caaatcacaa atttagatcg tttttatatt agtgttagtt tttctaacag ggataaaata
    21061 aatggtggat ttaaattgta cgacatcaaa atcgaagaag gctcaacagc cactccgtat
    21121 cagccaaact tactagatga cccttactgg gtaggtaaaa catcgttggg taagaatatt
    21181 gcaaataaag gtacgacgtt cccaattaaa tctagcgcgt acgaaatata taaaggtaac
    21241 acggaagaag agcttataat aggtcaaacg tatactatca cgcttaaagg aacaaaaccc
    21301 gcaagtcaaa cctttgtagc atataattat tggaacgtta attttggaga tctaaaacca
    21361 gttgagggat tgacagacgt atggtctcta acattcacac caacgaaact tgaaccgggt
    21421 ttgcctaaag accttcgcat ttttcagtcg cctaaagaaa cggccggcgc atgccgaatt
    21481 gactggctca agattgaaaa aggtgacact cgaaccccga atattgagca atataaatac
    21541 cgaggaatcg gcatgcgaga ctcaaacaat ccaaaatatt atgtatggga tctagaacct
    21601 agctatgttg agaataacct agctacagat atcaaggttg ctgaaattac tggtaaagca
    21661 aacaattata ccgatgggaa agtatcggag attaattcgc agttgactgc ttcaattaat
    21721 gaagtagaca ccacagctaa ggatgctcaa acaaaagcga atgctaatgc gactgctata
    21781 gatgaattag acaataagat cgatgaacgc attaatgata cagctactac cacattaaca
    21841 gttacaaacg ggaataccgg atcagcaaag ctttatcgtg aaggaaaaac agtttctata
    21901 tattttgtgg ctttaaacgg aaaacgcagt ggtggaaatg attcaacgat actaacaatt
    21961 ccagaaggct atcggccacc aattagtttt gagcaactgg ttggctcgat agaccgttct
    22021 actttgaaca gtgctcagtt atctattggt gcagatggag ccattaaatg gcgaagaaac
    22081 tcaagttatg gatcggatta tacctttgca attacttaca cgatttagaa aagcgtgaat
    22141 cgatatgaag gcagcatata gaccaattga accttacgga ttcgagcaaa tcattgtgaa
    22201 tgatgaagaa catttaccgg aagaatgcac agaagtcgaa ccaccgattc caaattggaa
    22261 accgaaattc aattactggg agggaaataa atgaaaaaca tttggaaata tggacgtact
    22321 ggcggagagt acgcaggaaa agtattggac gacatgcttg tatccgttcc ttacacagat
    22381 cagccaccgc ttgaaggaat tcgtgctgat ggcgaaccgt taacaatcgc tgatcaaatg
    22441 tttgatccta aattgaatca atggattatt ttagcgaacg cactagatca caacgattta
    22501 aacaatctca aagcaatgta tgagtcgtta gaaaatgaga acggcgattt aaaacagatc
    22561 aatgccaaac tcatgctaag cgatgtagca attaaacagg aaaatactgc attgaaagaa
    22621 aaagcggata gtttagcaca aatcaattca aaaatgatgc ttgcttcgtt acaaaatagc
    22681 aaagacattt cagaaattaa agagcaacta aatccagctt caaagggagg tgagtagtat
    22741 gtttagtttt agcgatgtga aaatgatgta tgattggggc tgtttcacta acgaacaagt
    22801 aatggttttc gttccgttgt gcattactga agaaaaagca gataaaatca ttagcaaaga
    22861 agagagcgca tcttaattga tgtgcttttt attttgattc aaggagttgt cacatgatta
    22921 atttagggga atggggagcg atagcaggat caataaccgc tatcgtttct ttgattttat
    22981 tagtaataaa accaattact gcatctttct cgaagattac tgagactctt tcaaaagtaa
    23041 gtcacaattt agatttgctg actaaagatt tagaatcgag caaatcagat cgattgatga
    23101 ttcatgaaga actaaagaaa cacga
//
LOCUS       DAMEEU010000049        23033 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.050, whole genome shotgun sequence.
ACCESSION   DAMEEU010000049 DAMEEU010000000
VERSION     DAMEEU010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 23033)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23033)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23033
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.050"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..2564)
                     /locus_tag="PB779_001843"
     CDS             complement(<1..2564)
                     /locus_tag="PB779_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739365.1"
                     /translation="MNQYVKKLIASILFVFPLLMVTSVFADVEKTSESTQSENQSFDK
                     TTFSEESITSETTESQSEAPTSNTRQEENKTSETSEVAEQTSDSSEEVQVRVVSADGY
                     SEAATTEELTQLLADESVAKIRLTQPLTLDRELEIKRDIVIDFGGLAHNFGTHHIYIN
                     ETPQSIEFQNFKGTAAHPGGLIPNIDGNAIIIAYMSDFWGNRYHFTGEIKFTGTLDLY
                     DGSKLGLIYAPRATVTLDGVSGVLDVQPVKEGMNAAPGKAYFCRSYQLNVINGSQLYG
                     PYLGKFYGFLDSGDETGSGKTAPGLHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVT
                     FKVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSRVAVSNDGKITINTATTGGFRLQG
                     DSSQIHVSSGGQISVKMAGDGDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSA
                     VRFENGTQKLTVTNGGSLKVRNAGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFT
                     VTGEKSNIDIRADSGATVDTTGDIDLNFMAGEKTYLVMVGKTGEDKTGIISGDVLNVD
                     LESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKAGVTFDNFEKDP
                     DYFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRV
                     PTNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSPVEITALTQGQTDE
                     NEGTGYNPWGEGEQGGLFEVQVPNEERLTTGDQVQIVAAKKVRGGQEVTELDSAKTTV
                     DVIPPEPAKLSTTLINAASRSITGTGEAGALVSLKKNQAVLSETTIDDTGKFVLSIP"
     gene            complement(2786..3670)
                     /locus_tag="PB779_001844"
     CDS             complement(2786..3670)
                     /locus_tag="PB779_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HDE0739366.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPEAINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSILLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            complement(3765..4202)
                     /locus_tag="PB779_001845"
     CDS             complement(3765..4202)
                     /locus_tag="PB779_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739367.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWVFYLVKK"
     gene            complement(4419..5330)
                     /locus_tag="PB779_001846"
     CDS             complement(4419..5330)
                     /locus_tag="PB779_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HDE0739368.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            complement(5707..6345)
                     /locus_tag="PB779_001847"
     CDS             complement(5707..6345)
                     /locus_tag="PB779_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739369.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDFVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFNQETKHLTGREKRLIKRNALSFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKEQVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            complement(6349..7119)
                     /locus_tag="PB779_001848"
     CDS             complement(6349..7119)
                     /locus_tag="PB779_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HDE0739370.1"
                     /translation="MIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQE
                     ISEKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSTYWERNILSGEIYPPLK
                     IKIGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFS
                     FFLLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIER
                     EPKYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            complement(7537..7953)
                     /locus_tag="PB779_001849"
     CDS             complement(7537..7953)
                     /locus_tag="PB779_001849"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739371.1"
                     /translation="MMTREKEAYERFILLFVERFNQAFHTDYATNIFEDFENSYSYSV
                     ISSTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNGFSLHQVLWCLLGKKKI
                     IITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGI"
     gene            complement(8004..8385)
                     /locus_tag="PB779_001850"
                     /pseudo
     CDS             complement(8004..8385)
                     /locus_tag="PB779_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339091.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            8511..9176
                     /locus_tag="PB779_001851"
     CDS             8511..9176
                     /locus_tag="PB779_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739372.1"
                     /translation="MNIGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHQTLGLPIDFPSIESATESIEPTLPDEPLVIKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETVDRFNPFLKPQIGYTTLPVGYVENSIEHWVCNDIFVHGTW
                     LSFHAGEVEKGKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILIQDYDDALKRSPQEP
                     DRH"
     gene            complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="PB779_001852"
     CDS             complement(9573..11606)
                     /gene="brxL"
                     /locus_tag="PB779_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease Lon-related BREX system protein BrxL"
                     /protein_id="HDE0739373.1"
                     /translation="MEQQEILKLSEFFPGKIVRKDLTKKIKEGANVPVYVLEYLLGMY
                     ASSLDETLVEKGVENVKNILARNYVRPDEAEKVKAKIRELGGYTVIDKVTVHLNEKKD
                     CYEAEFSNLGLKNVQISEEYPKKFDRLLGGGIWCIVSMEYWYDENDRWNSPFIAKKVD
                     PIQMPGLDIEAYKMARKEFTTNEWIDLLLRSIGMEPTQFNKRVKWLHLARLIPLIENN
                     FNLCELGPRGTGKSHVYKEISPNSILVSGGQTTVANLFYNMASRTMGLVGMWDCVAFD
                     EVAGIKFKDNDGVQIMKDYMASGSFARGKEEKNASASMAFVGNINQSVDVILKTSNLF
                     EPFPEVMGTDSAFLDRMHCYLPGWEIPKYRPDFFTNDYGFITDYFSEVMRELRKVSFG
                     DSFDKYFKLGSQLNQRDTIAVRRIVSGMMKLLYPDGRFEKSDVEEILRFALEMRRRVK
                     EQLKKIGGMEFYDVNFSYIDLEEEREEYVSVPEQGGGTLIPEGLGKPGHLYTVSYGKT
                     GQLGTYKLETQMTSGNGKFERTGINSDAGAREAMDSAYRYLRANYGSVSQSISLTTKD
                     FVVHVQDMNGIGMTKTLSLSTIIALCSVSLNKPVLPSLVILGDITIGGSMIKVDNLAN
                     CLQVAKDAGAKKVLVPMISAADIGTVPPELMGTFNLIFYQTPEDAVFKALGVE"
     gene            complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="PB779_001853"
     CDS             complement(11724..14246)
                     /gene="pglZ"
                     /locus_tag="PB779_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system phosphatase PglZ type A"
                     /protein_id="HDE0739374.1"
                     /translation="MTDINTQQIEEKLNQRFPNYGCRKIIFWFDSNQDFLEEIDSLVI
                     QNAKIYRLEKDAQFKTKRLLEYEDPETNYLIYAPFPRWDDKDEDNHLLSVLNYSEEFS
                     ADRLAIIMNELAIPLRFHQTVKQYRNFFNAKDRMRSFGEFSTHMTINKSETIELMIMA
                     VLLKSKSIRLNDLLRVVLKSFTESRENPLRELDKYQLTAKFWEFIQMKFGFTDSQPTL
                     EKLTMCLYLNYFYYQIDQEMPKKFKGFEILHLKANIITFMDQFMNDTRYMESFEQLSK
                     KVYQAIDGDGLLDSIEIDDLIEADVFSEIHAKILMFYAERLKASDTTTKIAGQTIFDS
                     LKQREKMHFASDYIYEYQLLKHAYYLVDKNRLCLPMNMDNLLTQYEKEMYWVDTHYRK
                     FIWNSDHIEEKQKYGQLYRLVEANYSKFLDQSGQIWNQTFEFKNRPSIRKFYNQAVMK
                     RSVKTVVIISDAFRYELGMNLERKLVREKKYSTNMASFLSVLPSVTEFGKAALLPNNQ
                     LTYNEGTEVLIDGKKTNGLSNRNAILQQRDANAVALNYDDVVKMNKAEVREVFNGKSV
                     IYIYHDQVDRTGDHSNENRVFEACDLAISEISRLINRLHNDGSIYRFIVTADHGFIYK
                     RSHVEEVDKIENPSRNEKDRVERRFILSEEEYEIIGTKNYSLGDSLGNDDTRNICVPI
                     TSSIFKKAGGGQSYVHGGSSIQEMLVPVLEITVAKGSNAKEPVAIELMTSNRRITGLS
                     TTLEFYQKNAISDVYDPASFWLYFEDEYGERISNEEIYVADSKTEDANQRFTKFVFEF
                     VNRRYTVEDTYYLVIKNQKNDLTERIKFIIDNPFAESFDFDI"
     gene            complement(14362..17994)
                     /gene="pglX"
                     /locus_tag="PB779_001854"
     CDS             complement(14362..17994)
                     /gene="pglX"
                     /locus_tag="PB779_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX-1 system adenine-specific
                     DNA-methyltransferase PglX"
                     /protein_id="HDE0739375.1"
                     /translation="MDKKAIKNFAVNARRKLIDEVMTKAKRLGIDESKIEDVKKIDSN
                     LQEIEKSGIRIQGKEIAQRNKLIAELKQRASVTSYSEAFQELIEEVAYTWFNRLIAIR
                     FMEVNDYLPDTYRVLSSEISGKIEPDIITDIYDADIFEELSSNEQQQVRTWKTDNSAE
                     AMDKLYQLIFIKICNQLNDYLPELFEEVEDYTELLFTASYIKKDGVIADLLSIPEDDF
                     YVQAGGQVEIIGWLYQYYNSEPHNQVVNIYKGIVKKQDIPAATQLFTTDWVVRYMVDN
                     SLGKYWLDHYPNSELRNKLKYLIPDKYAFEQATSVSNLKPEELKIIDNAMGSGHILVY
                     AFDVLMEIYLTLGYSERDAARAIVEYNLYGLEIDKRAYQLSYFAIMMKGRQYDRLFLK
                     KSLSPNLREFIDSPKVTDEYQERISELNNDKYSERWNEYKELIFDQFENGKELGSIIK
                     LVDKNNQAITKEYLGKVREYISKFNEFTNMDILYGMKEIQEKYLHILDVAEMLVDKYV
                     AVVTNPPYLNKMDKKLKKYVNDNYSDVKKDLFSVFIKLNSQMLIDNGYASFMTPFVWM
                     FISSYEKLRSFLINERNISSLIQMEYSAFEEATVPICTFTIKNSNEQDGSYIKLSDFK
                     GGMEVQKIKTLEAIHQHGECDYFYSTNQDNFKKIPGMPIAYWASDNVITDFAQGKLTN
                     DVADAKQGLATGNNNKFLRYWFEVEFNKIKFDAKTLEDAKKSRKKWFPTTKGGRFRKW
                     YGNNEYVVNWENDGDEIKNYVNENGKLKSRPQNLNYYFKKGITWSTLSSGQVSFRLQN
                     QAIFETKGSVLFSKDITDFEEIFGYVNSKLVNHFLTFISPTLDYHEGPMGKLPFLKVT
                     SERKLKKIREKVDENIDIARKDYNALETSYEFRRNILLSYMFKKDLSEAFNCLSRQLV
                     NQFNTLKSNEEELNDIFINHYSLEKELTKEVQDEYISARLPDKAREIKDFISYSIGCI
                     FGRYSLDEDGLIFAGGEWDPSRYQKFKPDTDNVLLITDDEYFKDSQIDIVNRFIDFVE
                     ITFGKETLEENLQFIADTLGGKGTSREIIRRYFVQDFYKDHLKTYSNRPIYWQLDSGK
                     QNGFKALMYLHRYTPDQLGKVRTEYLHELQKAYDNRIELRQQQISTSDNPKERNAMTK
                     EIVKIQKQLKEVREYDEKLGHLALKRIELDLDDGVIVNYDKLQRDPKTGEKFQIFAKG
                     VKEPKK"
     gene            complement(18058..21729)
                     /gene="brxC"
                     /locus_tag="PB779_001855"
     CDS             complement(18058..21729)
                     /gene="brxC"
                     /locus_tag="PB779_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BREX system P-loop protein BrxC"
                     /protein_id="HDE0739376.1"
                     /translation="MLIKDIFAKPIDRNIQGVIKVGQAKDENVQQELEEYVVTKELQK
                     HFKTIFDAYQRSINTPTDKMGVWIQGFFGSGKSHFLKIISYLLANREINDKKAIDYFK
                     EDGKIKDPLTLATMERCSQINTDVILFNIDSKSDAGGKKDKNGIVNVFLKVFNEMQGL
                     STIPHLADFERRLIKEEKFDAFKAAFEEINGAKWQEERHEFDWIQDDIKEAALKIDFM
                     SEAAIDNFLEKASGNYLISIDDFANLVKSYLDSKEADHHIAFLVDEVGQYIGGNRELT
                     LQLQTVVEDLGRICEGKAWVLVTSQEAIDHVTNFDNNSDNDFSKIKDRFATTVSLSSA
                     NADEVIKERILKKKEFANDSLALQFETVQTELKNKLLFVDSPELKLFQDAENYAEVYP
                     FIPYQFNLLGQILTEIRNHSYQGSNLSSGERSLLAMFKEAAERNKENDTTSLVSLDQF
                     YYSLERWIDTAISRVITQATNNSHIQRPTDIDNFNVNVLRILFMIKYVDQAIKPNVEN
                     ITSLMIRNINEDRLETKKRVEEALDLLIKENFVRKNLDSYIFQTDEEQEITREIKNQN
                     ITDSDLIVELSKRIFDGVLDRNSFAYEKLGMSGGNKFKNRYTFTYAQVLDQRPYKQAG
                     NAEMTVNFISPYSDLAGQEAELALKSSRNLLFVELPSDKEFKDDIAMYARMNLYLTTT
                     YSSVVKNFDAIRSEKSGELQELSASINDQLNELLKSAKFFYNGAEIQLTGSDFKAKFQ
                     SALQKMAEEVYHKLNQIDAPKEKEDILYLVKESKNEIIEDPSNEQAVQEIFNFINDQK
                     RNHLTITMKTIRDRFETKQPYGFTELDVEWCIAKLFMSGKIDLLYNNVQISRMDDPNS
                     IVMIIQKRRESEKIKIEPSAVISPKAKKLVDEIGRELFQSRNIVDENNNEHTMENFKK
                     YLKGQLDNLRSYFDLQNTYTYPSAYEYEQIKKYLEVIVQTSDVEDFFYTIKKYRDELF
                     DWAETYDKIKNFHKQNSTQKKIWENAQDKIRLIEKSRRQTSSQEIDQLIHEMKTILKK
                     ADPYSDMMKLNELIQEFIEQYNQLLELESQEILNKLTEEKQATFKLLEGKDFKDQFVP
                     IVDQEFQELKAKIEQANTIDDLVFLSLNVAEQYLIFNQRFDNEENRRRQEEQARKQIE
                     AANLIRETEKDEIDSAAKAEEIAIVKPTIQQKTVPMRTLNVHVKTIKSAADIDELTAE
                     INQKLKEQLQENTEITIQF"
     gene            complement(21754..22329)
                     /locus_tag="PB779_001856"
     CDS             complement(21754..22329)
                     /locus_tag="PB779_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1788 domain-containing protein"
                     /protein_id="HDE0739377.1"
                     /translation="MSLSIQEHLEKLNEVIQKEDFLLNRGLGNEVGYYIFDYDPKDEL
                     IVRDYINDISGTSVGDNYEVKVYNLYVIMLEYLEKRGFTEKAIKMEERRGLQKLVESI
                     GRLLKMDLPEEENVFFEYVDAHTPEKSVVFLTGIGELYPLIRAHSILNKMHQVFDRVP
                     VVMMYPGEYDELSLTILNTNKDDNYYRAFRI"
     gene            complement(22329..22928)
                     /locus_tag="PB779_001857"
     CDS             complement(22329..22928)
                     /locus_tag="PB779_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1819 family protein"
                     /protein_id="HDE0739378.1"
                     /translation="MNKKYSAGLVSKRFWFSEFKLYIQLRLEGYTDIEIKEKNEHENI
                     FFAVSSNRQKEIYQNVKRRVSQLDEAGLQLFNQLNIDNQKLVNLISILMIDDLFNEFM
                     TEVYAENLRKGNLQLTPVDYRSFFTEKRRSSEDISKWKDYTIKRLIAAYQTNLIETGL
                     VRGEKEYGRMTPILLDKRLIQWLVDKNRKDIVLALGGIL"
BASE COUNT         6993 a         4531 c         3343 g         8166 t
ORIGIN      
        1 gggatagaaa gaacaaattt acctgtatca tcaatagttg tttcggacaa aacagcttga
       61 ttttttttca atgaaaccaa agctcctgct tcgcctgtac ctgtgattga gcgagaagct
      121 gcattgatca atgtggtact taatttagca ggctcaggag gaatcacatc gactgtcgtt
      181 ttggcagagt ccagttctgt cacttcttgg ccgcctctta cttttttagc agcaactatt
      241 tgcacttgat cccccgttgt tagtctttct tcgttgggta cttgaacctc aaacaaaccg
      301 ccttgttcgc cttctcccca cggattatat cctgtccctt cattttcatc tgtttgtcct
      361 tgtgtgagag cagtaatttc tacaggtgat ttcgtcgtat ctgcataagt aatacgtaaa
      421 gtcacttcta cttcgcctgt ccaagcatct cttggctttg cctcgacacc ttcgggaaca
      481 acgacatgcc catagatttt tttatctgca ttcgttggta ctcttaagga ttcaatcatc
      541 ggaagctggt tattggcact gattcgatta taatttttca ttccggcacc tgtctgagca
      601 aattcatttg ttaaacctgc actagggctt gatacaaaat tacctaagtc ggttccattg
      661 atcgataagt ctgtcatatc agaaaaataa tccggatctt tttcaaagtt atcgaacgtt
      721 actcctgcct ttcgccataa agcaatttct gaatgagcga tcttcaaaga agaatcgcca
      781 tttccttgaa atacccagcc acctatgcca ttagtctcgc ttccgatccg tttgttttgg
      841 aaatcgaaat aggtaggaga ttctaagtct acattcaaca catccccact gatgatgcca
      901 gtcttatctt ccccagtttt cccgaccatg actaaataag ttttttcgcc agccataaag
      961 ttcaaatcaa tatctccagt tgtatctacg gtagctccgg aatctgcgcg tatatcgata
     1021 tttgattttt ctccagtaac cgtaaaatca gctgaccctg gactttctag aaaaccagaa
     1081 gcgtcataaa attggatcgc ttggtttcct tgattgagtc tgttcacata agatttgcca
     1141 tcccctgcat ttcttacctt caatgagcct ccattagtta ctgttagttt ttgcgtaccg
     1201 ttctcaaaac gaactgcgct agaacgacca ctttgcttat caatatcgat gactgatccg
     1261 gctccttcta cgatcaaaga aagtcctttc cctacaaaac gcatcccatt gtttccaggt
     1321 tggtcgccat ctccagccat tttgaccgag atttgtccac cacttgatac atggatttga
     1381 ctagaatctc cttgcaggcg aaatccgcca gtagtcgctg tattgattgt gattttccca
     1441 tcattcgaca cagcgactct tgatcctgag cctctcattt ggataattcc gcgattgttg
     1501 tcgttggtaa tattgatctt tgtatttacc gaaaattcac ttcctgagcc actgacttta
     1561 aatgtgacat tcccgggtag cgtatcgaca gcctctcctt catcgctgac gccatctgcc
     1621 cgatcatagt caagagagac ctttgaacca ctcaagatat ggagtcctgg tgctgttttt
     1681 ccactgcccg tctcatcacc tgaatctaga aaaccataga attttcctag atatggtcca
     1741 taaagctgac taccattgat tacatttagc tgatagcttc tacaaaaata agctttaccc
     1801 ggagcggcat tcatcccttc tttcactggt tggacatcca atacaccgga aacaccatct
     1861 aatgtgacag ttgcacgagg ggcgtaaatc aggcctaatt tagaaccatc atataagtca
     1921 agtgtcccgg taaattttat ttctcccgta aaatgatatc tgtttcccca aaaatcggac
     1981 atataagcaa tgataatggc atttccatcg atatttggta tcaacccacc tggatgagct
     2041 gccgttcctt taaaattctg aaactcgatc gactgaggtg tctcattgat atagatgtga
     2101 tgtgtgccga aattatgagc aagtccgcca aaatcgataa cgatatctcg cttgatctcc
     2161 aattccctgt ctaaagtcaa aggctgagtt aaacgaatct tagctactga ttcgtctgcg
     2221 agaagctgcg tcagttcttc tgttgtggca gcttcgctgt acccatccgc tgaaacaact
     2281 ctaacctgta cctcttcact gctatcagac gtttgttcag ctacttctga ggtctcactt
     2341 gtcttatttt cttcttgcct tgtattagaa gtaggcgcct cactttggga ttctgtagtt
     2401 tcagaagtaa ttgattcttc tgaaaaagta gtcttgtcaa aactttgatt ctctgattgc
     2461 gttgattcgc ttgttttctc tacatcggca aaaacggatg tcaccatcaa gagagggaag
     2521 acaaacaaaa tcgacgcaat cagctttttt acatattgat tcattctcca ccatcctctc
     2581 tgacgttttg acaattttat tttaacgttt taatttattt gtaattgtac tttcatattt
     2641 aaaatatgta tttttatggc aaatttttct gttaggtgaa aatttctttt ttgtacaaaa
     2701 aaaggctgtg acaaaagtct tgtcacagtc ccttattccg aacaaccgat gtcctcctga
     2761 caactcttcg gtcacaacct ccattttaac aataaacctg taaatgtgag ggtaacactt
     2821 tgattgtcac aggtaattta tccccttcat ctccatcaac attcgtcgtc aattcttcct
     2881 catcagctaa tgacacaact aattgctcac aagtaagata ggctagattt ttcgtagatt
     2941 catctactcc ttttaatagg tctggcaatg ttttaagcgt atcgatcaaa gaagaatctt
     3001 ttaaataaac caaatggagc ttaccatcat ccacttttgc atttggaagt aatgtttcaa
     3061 aaccgcctac tgagttagtt agtcctatca gcaagatact gctctcaatt tcttccttct
     3121 ttccatcaac ttctacgtga aacgagtagg attgtgtgga agctaactgt ttgattcctg
     3181 acatgaaata agctagtttt ccaaatttcg tcttcttctc cgcatctaca tcattgattg
     3241 cttcagggat agagccaatt gcgacgacat tcataaaata gtcgtcattt atttttccaa
     3301 tatccaatgg cttgactgat tcaatcgaaa aatgattgat cgcttcctca ggttctagcg
     3361 gtatccctaa tgctcgagcc aagtcattca ccgtacccaa tgggaaaaat ccgaaatttg
     3421 gccgatgttc ttgttcagcg attccactga ttccttcgtt gactgttcca tctccgccca
     3481 tgacaaacac actatgatac ccttccgtag ccgcttcgcg agtaaagttt tttgcatccc
     3541 ctgctttttt tgtatgcaag acgaccactt catcaaacac cgattccaat tttgctatcg
     3601 ctaattgctc aaattccttt gcttgttcac cgcctgaact ggggtttacc actaataaaa
     3661 cttttttcat cactttcttt cccttctgat tgatttcttt aatataacga tagcataaag
     3721 aaaaaaatta ggctgtgatg aagtactgtt catgaaacat tcatttattt tttgacaaga
     3781 taaaataccc atactatgaa actgaggaaa attaaaacaa tgatatagga aataaaagaa
     3841 aatgataggc attgtatacc taataaagta aaaatcttag gtggcagata aaaacacaaa
     3901 aatagcaaga gaatgtaata gcgtttcttc cactttttgt tatcagacct tatagcgatc
     3961 agaggaatac caaatgcata actgaaaaac tcttgatgta ctgttaatat gtcacgacct
     4021 tgaataataa atgcaacaat ccccgctata attagtgtgc ctaataccaa aacggaaaat
     4081 tgatgaatat attttatata caaatgatcc attgtacttc ctgccttttt atttgtgaga
     4141 aaaacaaatc cgtatacgtg aataacttct agaaataaaa gaaatttgca aaaccactcc
     4201 atttatctac ttctacgtgc attttttaat atcgttttct ttatttaaga ttatacagaa
     4261 aaatatctag ggtggctgga ttctaagtaa aaaaaatttt taaaataaaa agaactaaat
     4321 caagtaataa ttaaactact gttgatttag ttctaataaa aagatttaga tgaacagttt
     4381 tattgattta aatagttcat attttttatt tataccgctt atttactact tgctgtacta
     4441 gaatctgaag tgaatgtact caaaacattt tcaaagtctt tgtctttgat ttttacatta
     4501 gcgtctttca atacttcgcc aattacttta ttctggaagg tactgtcact taattttgtg
     4561 tctgttgcaa tttctttcaa ttcttttttg tatttatcca tgtcgttgcc tttgttttgg
     4621 tttttcacca ttttaaccac ataatattcc gtagtataag ttgaagcatt ggtagaagtg
     4681 atcacatcag aaacttgacc atctttcaac ttaaaggctg cttctttgac ttctgccgga
     4741 accgttgtag tagtggaatc aaatttcact tttccgccat cttcttttgt cgtagtatca
     4801 gttgacttgt ctttggctaa tttagagaaa tcgtctccct tatcagcagc tttcttcaca
     4861 tcttttgcat catcttcact tgctacttgg ataatttgag cttccacttc tggatggaaa
     4921 gattcccaag ccgtttttaa atcttcatcg gtcaatttga tatgtttctt tagaccttct
     4981 tgaaaggcta gactttgttt gatactgtct ttgaatgttt gttctgtgta acctgcagat
     5041 ttcaattgtg aatcaaatga atcacccaat tgtttctttg tttgatcata ttgggaatcg
     5101 atttctttgg ttgatacgtc atctccatat ttatcttcaa atacttgata aacgatcaac
     5161 tgttgcacag cggaatctgc tccttgcatt tttttcaagc tatccattac ttcttgttcg
     5221 ctgattgtac cgcctttata actaacggct gttttttcac cggcattcgt acagcctgac
     5281 aataagccag tgcctagtac gatggcaagt gctaaaaatc tttttttcat ttatcaattc
     5341 tcctactttt cgttttttgc gaattgctaa aaacaaaggt gttcaagatg aaaatcatca
     5401 agaacacctt tactaatctg ctcgatacgt cctgaataga tataaggcta cacaatccag
     5461 aaagttcgct cagcagaata aatgtcaagt agcacatcac accttaatat actacttctt
     5521 ttgttaccgt ttttcaagtc tatcttgcgt tccgtattta acgtaactaa ttcttagaac
     5581 aaatgttatc gattttgttt ttcttcttcc gctgttggga tattcaaatc agacactttt
     5641 atgttcgatt ttccagacat ttttttgttg tttttattag aaaaagtttg ttttttcatt
     5701 tgttttctaa agcatgatct tcttgtttcc tattttggtc agatatggat catgcgtgac
     5761 cacgataact aacgtacctt gggaagcctg ttgcgataag atttcaacga cttgctcctt
     5821 atttcgttta tctaatgatc cagttggttc atcggctaaa atgattttgc tattcttcaa
     5881 taagactctc gcacaggcga ttctttgctt ctcaccacca gataatgtgt agataggcgt
     5941 acttagcttc ttgtttatat ttactttttt caatgcctca tactttgctg ttcgcttatc
     6001 tgaaacattt aaattcgaaa acttcaatcc aatatctaaa ttaaaatcga ttgtttcata
     6061 ttcaatcaac ccaaaatctt gaaaaagaaa agagagggca tttcttttta tcaagcgctt
     6121 ctctcttcca gttaaatgtt ttgtttcttg attaaataaa taaaattgcc ctgaactgaa
     6181 ttgatcattc aatcctaata tattcaataa agtacttttc cctgctccgc tctctccaac
     6241 tacagtcaca aaatccccag catccgcagt gaaacgatcc aaatgaagaa tcgttttgtt
     6301 tcgaatgatt tttttcgcac cttttatcac tatcaacggc tccaattgtt aacctccatt
     6361 catcagcaat aactgacttt tcttttctgt agacaaaata aaaacaactg aaagaataaa
     6421 atcaatgaag ctaaagaaaa aaatattaaa aagatattta ggctctcttt ctataagaaa
     6481 aaggaagatt acacttgtcg ttccccattt gatgaggttc atcatgaaga aatctttata
     6541 cgtttcaaag agcgaataac cacttgaacg aaagatagcg attttccgac aattgtagac
     6601 aaaatatatg cataacatga catagctcaa caagaagaaa gaaaagaaag tgagtaaaaa
     6661 tatctgtatc aagtaatgaa atgatctgct taacactttg acagctatct cttcagtctg
     6721 agtatacgga aatgataact gcaagttatc acgtaactga ctttcttcaa tcagctcaaa
     6781 taacctttct ttcgacaaag agcctatctt gatctttaac ggtggataga tttctccgct
     6841 gagaatattt ctttcccaat acgtactgtt tttcaatgtc agtatttcaa caaccggata
     6901 atgttcgatc caggggatag aaggaataaa tgtataaatg ggttgattgt tttttataaa
     6961 tagaaatttc ggttcttttt cactgatttc ttgataatat tctgttattt gcgccaggtc
     7021 attttttaaa tctgtatgtc tatatcgttc agggatcaat ataacagggt gcgtttcttt
     7081 ttcggttatt tggatcaacc ttccagagac atcaatcaaa ggaaatttct taagataatt
     7141 cagatttatt tttatccctc tgccaaactg ttcattttct tcattcaagt aatctgatac
     7201 attgactaat atacttccgt ttttattcaa agtttcatat aattcctgat cggctgctga
     7261 tgcaaaacga ttggaataaa taaaatccac gtggtttttc ccgatggtta ctggataaaa
     7321 tacatgatag tcctcaccag cgatttcttt tggtgtttca tgggaaacag ctaactgtga
     7381 agaagaaaaa acgatagttg ctaattcgac attggcaacg gtcaaaagaa gagaaaacaa
     7441 caatccaaat gtaaaaagaa tgtattggat atagttgaac gcttctctta acgaagcgat
     7501 tttttcaact aataaaagag aaatcaaaga gataccctat attccgctga acaagaaaac
     7561 gtacatctgg aacaaataaa gaaattgctc cttataatac ataaaaataa aaccaccaat
     7621 gattcctgca attatgaatg taataatgat tttctttttc cccaataaac accacaatac
     7681 ttgatgtaat gaaaagccat tattcaacaa taaactgatt tctttattca tcaataagaa
     7741 aaaggatgat aacaaaagga ataaaagaat caatccaata gttaaataca ctcgataatt
     7801 atatacgtct gtacttgaaa taaccgaata cgaatagcta ttttcaaagt cttcaaaaat
     7861 attagtggca taatcagtgt gaaatgcttg attgaatcgt tccacaaata gtaaaatgaa
     7921 ccgttcatag gcttcttttt ctctcgtcat caagaaaaat tcaccttcaa aatcttttat
     7981 tttgatcgat tcttcaatgg acgttacgcg aaaggaggta ttagaatagg gtaccttctc
     8041 gtgagaagat ttgacatccc cttgataata caatgtcatt tcaagctttg gctgtatctt
     8101 gaagttccaa gatgtatcta cttcattgga ttcatttact gtttttttca tataagaaag
     8161 ctcagtttct gatgagacat tttcaaatac catgattagc tgctcatatt cttcttgccc
     8221 aataaaatgt tgtggcaatc gaatcggagt ataagtatct gtttgatgga aaaattcatt
     8281 tgtccgatag agtacctgtt tatttataat aaccaaggca aaaccactca tgataccggt
     8341 cactatgatt gtgagtaaaa ctgtgaactt ttttttgatt atcaccactc tcccttactt
     8401 aaatgattct ttgataaaat cataccgttt ttcatcaaaa aaacgtatct atcaaatgta
     8461 taggtcatgt agaataaatc tatatactgt agaatcgaaa ggagaagaag atgaacatcg
     8521 gagaaaaaat acgaacttac cgcagaaatt gtaagcttac gcaaaaagaa ttaggcgaaa
     8581 aaatcggtgt ttccgataaa acaatctcta gttgggaaaa ttctcgtaca atgccagacc
     8641 ttgaaatgct gtcactttta catcagactt taggtctgcc gattgatttt ccttctattg
     8701 aatcagctac cgaatcaata gaaccaacat tgccggatga acctcttgtt atcaagaaat
     8761 cttattcatc aaaacaaccc ttctcactca aaaagacact atctttcttt ctgctcgtct
     8821 tttgtttggt ctatcttttt cttatcaatt atcaatataa aaatgaaacg gttgatcgat
     8881 tcaatccttt tttgaaacca caaatcggct ataccacact ccctgtagga tacgtggaaa
     8941 attccatcga acattgggta tgtaatgata tctttgttca tggtacatgg ctgtcttttc
     9001 acgctggaga ggtagaaaaa ggtaagaatc atgctgtaat caaacacaaa ggaaaacacg
     9061 tcatgaacgt tcgcctgctc acttgggaag ccattccctc agattaccaa gaaatcctca
     9121 tccaagacta tgacgatgcc ttaaaaagaa gccctcagga gccagatagg cattaagtag
     9181 gagatgaacg tagagataga aaaaatcaat gcacatgatc ttatcaaaaa aaaacagggg
     9241 tacaaattaa ttgaaaaagc tttgagatga aagttcctaa ataaaaaagt tcagaatgat
     9301 aggtaaaaaa atgactaact attctagtat taggctattt gtattattct tctgttattt
     9361 ttatatcaaa aaatccagaa ataactaaat ataggtattt ctggcttata gtataatatt
     9421 tacgccacag cccccaatga ttctttttgg aatcatgatc aaggacggac atacacaaaa
     9481 atattttgcc cattcgatcc gaatagatta acgactaatc tagtaagtaa tatagattgg
     9541 tacgtagtca aaccagcaaa tggaaaagtt gtctattcca ccccaagggc tttaaagaca
     9601 gcatcttccg gcgtttgata aaaaatcaaa ttaaaggtac ccattaattc tgggggtaca
     9661 gttccaatat cagcagcgct tatcataggt acaagtactt ttttcgctcc ggcatctttt
     9721 gctacttgta aacagttagc taaattatct accttaatca tagaaccacc aattgtaata
     9781 tcccctaaaa taactaaact tggtaataca ggtttattta aggaaactga gcataaagct
     9841 attatagttg ataacgataa tgtttttgtc ataccaatgc cattcatatc ttgaacatga
     9901 acgacaaaat cttttgtcgt caaactaata gactgactaa cacttccata attagctctt
     9961 aaatatcggt atgccgaatc catcgcttct cttgctccag catctgaatt gatcccagta
    10021 cgttcaaact ttccatttcc cgaagtcatt tgcgtttcca atttataggt acctaattgc
    10081 ccagttttgc cataagatac cgtgtacaaa tgccctggct tccctaaccc ttctggaatc
    10141 aaagttcctc caccttgttc aggaacagaa acatactctt ctcgctcttc ttctaaatca
    10201 atgtatgaaa aattgacatc ataaaattcc attccaccaa ttttctttaa ttgttctttt
    10261 acacgacgac gcatttcaag agcaaatctt agtatttctt cgacatcact tttttcaaat
    10321 ctaccatcag gatacaacag tttcatcatc ccagatacaa tccgacgaac tgcaatcgta
    10381 tcccgctgat ttaattgaga accaagtttg aaatatttat caaaactatc gccaaaacta
    10441 acttttcgaa gctcacgcat gacttcagaa aaataatctg taatgaagcc atagtcattt
    10501 gtaaaaaaat ctggtcgata tttaggaatt tcccaacctg gtaaataaca atgcatccga
    10561 tccaaaaagg ctgaatccgt ccccataacc tccggaaatg gctcaaataa attcgaagtt
    10621 ttcaatatta catcaacgct ttgattaata tttcctacaa aagccattga tgctgaagca
    10681 ttcttttctt ctttgcctct agcaaaagat cctgaagcca tgtaatcttt catgatttga
    10741 acgccatcat tatccttaaa tttaatccca gcaacttcgt caaaagcaac acagtcccac
    10801 atacctacaa gtcccattgt acgactagcc atattataga aaaggtttgc tactgttgtt
    10861 tgtccacctg aaacaaggat tgagtttggt gaaatttctt tatatacatg cgatttacct
    10921 gtaccacgtg gtcctagttc acagagatta aaattatttt caattaatgg aataagtctt
    10981 gctaaatgaa gccattttac ccttttatta aattgtgtag gttccatacc aatggaccgt
    11041 agaagtaagt caatccattc atttgtagta aactccttgc gagccatctt gtaagcctca
    11101 atgtctaaac caggcatttg gattggatca accttttttg caataaaagg gctattccaa
    11161 cgatcattct catcatacca atattccatc gaaacaatac accagatccc cccacctaat
    11221 aatcgatcaa attttttcgg atactcttca ctaatttgaa cattttttaa tcccaggtta
    11281 gagaattctg cttcataaca atctttcttt tcatttaaat gtacagttac tttatcaata
    11341 actgtataac cacccaattc acgaattttt gcttttactt tttctgcttc atcaggacgc
    11401 acatagtttc gagcaagaat atttttaaca ttttccacac ctttttcaac caatgtttca
    11461 tccaatgacg aagcatacat accaagtaaa tattccaata cataaacagg tacattcgca
    11521 ccttctttaa ttttctttgt taaatctttt ctgacaatct ttccgggaaa gaattcagat
    11581 aactttaaaa tttcctgttg ttccactaga attcctccat gtgttcagtc attataatag
    11641 caattaaagt atatcatact taaccagtag gcttgataat acaaaagaaa aagtatccac
    11701 aaaaaattgt ggatacctcg tttttatata tcaaaatcaa atgattctgc aaaaggatta
    11761 tctataatga attttattcg ctcggtcaaa tcattttttt gattttttat cactaaataa
    11821 taagtatctt caactgtata tcgacgattt acaaattcaa aaacaaattt agtaaaccgc
    11881 tgatttgcat cttctgtttt tgaatccgca acatagattt cttcatttga gatacgttca
    11941 ccatattcat cttcaaaata aagccagaaa gatgcggggt cataaacatc actaattgca
    12001 tttttttgat agaattctaa cgtggttgat aatcctgtaa ttctgcggtt gctagtcatt
    12061 aattcaattg ctactggttc ctttgcattg ctacctttgg ctaccgtaat ttctagaaca
    12121 gggactagca tttcttgaat agatgaccct ccatgaacgt agctttgtcc cccgccagct
    12181 ttcttaaaaa tacttgaagt aatcgggaca caaatgtttc tagtgtcatc atttcctaaa
    12241 gaatctccca aagagtaatt tttcgtacca attatttcgt attcttcttc actaagaata
    12301 aaacgacgtt ctacacgatc tttttcattt ctagatggat tttcaatctt atctacttct
    12361 tcaacgtggc ttcttttata aataaatcca tgatcagccg taactataaa acgatagata
    12421 ctgccatcat tatgcaagcg attaataagt cgggaaattt cgcttatcgc taaatcacag
    12481 gcctcaaaaa ctcgattttc attcgagtga tcacctgttc tatccacttg atcgtgataa
    12541 atataaatga ctgatttgcc attaaatact tctcgtacct cagccttatt catcttaacc
    12601 acatcatcat aatttaaagc tacagcattt gcatctcgtt gctggagaat cgcatttcga
    12661 ttggataaac cattcgtttt tttcccatca atcagtactt ctgttccttc attgtaagtt
    12721 agttgattgt ttggtaataa ggcggcttta ccgaattcag taactgaagg taatacagaa
    12781 agaaagctag ccatgtttgt tgaatacttc ttttctctaa ctaacttacg ttctaaattc
    12841 atccctaact catatcgaaa agcatctgaa ataataacta cagttttaac agagcgtttc
    12901 attacagctt gattataaaa ttttcgaatg gatggacgat tcttaaattc aaaagtttga
    12961 ttccaaattt gtcctgattg atcaagaaac ttcgaataat ttgcttcaac taatcgatac
    13021 aattggccat atttttgctt ttcttctata tgatcactat tccaaataaa tttccgataa
    13081 tgcgtatcaa cccaatacat ttccttctca tattgagtta gcaaattatc catgttcatc
    13141 ggcaagcaca atctgttttt atccacaaga taataagcat gtttcaataa ttgatactca
    13201 taaatataat ccgatgcgaa atgcattttt tcgcgctgct ttaaactatc aaaaattgtt
    13261 tgtcctgcaa ttttcgttgt agtgtcagaa gcctttaatc gttctgcata aaacattaat
    13321 atttttgcat gaatctcaga aaatacgtct gcttcaatta gatcatcaat ttctatactg
    13381 tctaataatc catcaccatc aatagcctga tatacttttt tagatagctg ttcaaagctt
    13441 tccatgtaac gtgtatcatt cataaactga tccatgaaag taataatgtt tgctttcaaa
    13501 tgtagtattt caaatccttt gaacttcttc ggcatctctt gatcaatttg ataataaaaa
    13561 tagttcaaat aaagacacat cgtcagcttt tccaatgttg gctggctatc cgtaaagcca
    13621 aatttcattt gaataaattc ccaaaattta gctgttaact gatacttatc aagttccctt
    13681 aaaggattct ccctactttc tgtaaagctt tttagaacta cacgcagtaa atcatttaat
    13741 cgaatacttt tcgatttcaa caaaacagcc attatcatta attcaatcgt ttctgattta
    13801 ttaattgtca tatgcgtact aaattcacca aaacttctca tgcgatcctt tgcattaaag
    13861 aaattacgat actgtttaac tgtctgatga aatctaagtg gaatagccaa ttcattcatg
    13921 ataatcgcta agcggtctgc actaaattcc tctgaataat tcaatacact caacaaatga
    13981 ttatcttcat ctttatcatc ccaacgagga aatggcgcat agattaaata gttagtttcg
    14041 ggatcttcat attccaataa acgcttagtt ttaaattgtg cgtccttttc taatcgatag
    14101 atttttgcat tttgaatgac caatgagtca atttcttcaa gaaaatcctg atttgaatca
    14161 aaccaaaaaa tgattttcct acatccataa ttaggaaaac gttgatttaa tttttcttca
    14221 atttgttgcg tatttatatc tgtcatcaat ctcacctaat cgttctcttt ctatacccct
    14281 tatattgaca taatttggat aatttcgcac gcaatttaag aataaaaaag aaagttgtta
    14341 gaaaacaact ttcttagata actatttttt tggttctttg accccttttg caaaaatttg
    14401 gaatttctcg ccggttttag gatcacgctg caacttatca taattgacaa ttacaccatc
    14461 atctaagtct aattcaattc gttttaatgc taagtgaccc aacttctcgt catactcacg
    14521 aacttctttt aattgcttct gaatctttac aatttctttt gtcattgcat ttctttcttt
    14581 tgggttatca cttgttgaaa tttgttgctg acgcaattcg attcgattgt catacgcttt
    14641 ttgtagttcg tgtaggtatt cagtacgtac ttttcctaat tgatctggtg tatagcgatg
    14701 caagtacatt aacgctttaa agccattttg ttttcctgag tccaattgcc aataaattgg
    14761 tcgattggag tatgttttta aatggtcttt gtaaaaatct tgtacgaagt aacgacgaat
    14821 aatttctcga cttgtccctt tgccacctaa agtgtcagcg ataaactgga gattttcttc
    14881 aagggtttct ttaccaaaag taatctcaac gaaatcaatg aaacgattga caatgtcaat
    14941 ttggctatcc ttgaaatact catcatcggt gatgagtaaa acattatcag tatcaggttt
    15001 aaatttttga tagcgggaag gatcccattc gccgccagcg aagatgagac catcttcgtc
    15061 tagggagtaa cgaccgaaga tacaacctat tgaataagaa ataaaatcct taatttccct
    15121 cgccttatca ggtaaccttg cagagatata ttcatcttga acctcttttg ttaattcttt
    15181 ttcaagagaa taatgattaa tgaatatgtc gttcagttcc tcttcattcg attttagagt
    15241 attaaattga ttaaccaact gcctacttag acagttaaat gcctctgaga gatctttttt
    15301 aaacatataa cttaacaaaa tgtttcttct aaactcgtat gacgtttcaa gagcattata
    15361 gtcttttcta gctatatcga tattttcatc cactttttct cttatttttt ttaattttct
    15421 ctcagatgta actttaagaa aaggtagttt tcccattggt ccttcatggt aatccaaggt
    15481 gggagaaata aaagttaaaa agtgattaac taatttagag tttacatagc caaatatttc
    15541 ttcaaagtca gttatatcct ttgagaacag aacagatcct ttagtttcaa aaattgcctg
    15601 attctgcaat ctaaaagata cttgtccaga tgaaagtgtc gaccaagtaa ttcccttttt
    15661 aaaatagtaa ttaagatttt gtggtctaga ttttaacttc ccattttcat taacataatt
    15721 ttttatttca tctccatcat tctcccagtt aaccacgtat tcattgtttc cataccattt
    15781 tctaaaacga ccacctttag ttgtaggaaa ccattttttt ctagactttt tagcgtcctc
    15841 taatgtttta gcatcaaact ttattttgtt aaattctact tcaaaccaat accgcaaaaa
    15901 tttattgtta tttccggttg ccaacccttg ttttgcatct gcaacatcgt tagttaattt
    15961 tccttgagca aaatcagtga ttacgttatc gcttgcccag taagcaatcg gcattcctgg
    16021 gatttttttg aagttgtctt gattagtact ataaaaataa tcgcattcac catgctgatg
    16081 aattgcttct aacgttttaa ttttttgaac ttccattcca cctttaaaat ctgataattt
    16141 tatatagctt ccatcttgtt catttgaatt ttttatcgta aacgtacaaa ttggaacggt
    16201 tgcttcttca aaagctgaat actccatttg aatcaaacta gaaatgtttc tttcattaat
    16261 taaaaatgag cgtaactttt catagctaga aatgaacatc caaacaaatg gcgtcataaa
    16321 ggaagcatat ccattatcaa tcagcatttg gctattcaat ttaataaaca cagaaaatag
    16381 atcttttttg acatcagaat agttatcatt tacatatttt tttaatttct tatccatttt
    16441 attaagataa ggcggattag tgactaccgc tacatattta tcaactagca tttcagccac
    16501 gtcaagaatg tgcaagtatt tttcttgtat ttccttcatc ccataaagaa tatccatatt
    16561 cgtaaattcg ttgaattttg atatatactc tcttactttt cctaagtatt ctttagttat
    16621 tgcctgatta tttttatcga ctaacttaat gattgatcca agttctttcc cattttcaaa
    16681 ttgatcaaaa attaactctt tgtattcatt ccagcgttca ctatacttat cattgttcaa
    16741 ttcactaata cgctcttgat actcgtctgt cactttagga gaatcaataa actctcttaa
    16801 attcggcgat agactttttt tcaaaaaaag acgatcgtat tgacgccctt tcatcataat
    16861 tgcaaaataa gacaattgat acgctctttt atcgatttca agaccatata aattgtattc
    16921 aacgattgca cgtgcagcat cacgctcaga atatcctaac gtaagataaa tttccatcaa
    16981 tacatcgaag gcgtaaacta aaatatgccc agaccccatt gcgttatcga taatttttag
    17041 ttcttctggt tttaaattac ttacagatgt tgcttgttca aaagcatatt tatctggaat
    17101 taagtatttc aacttatttc ttaattcact attgggataa tgatctaacc aatactttcc
    17161 taaactattg tcaaccatat aacgaacgac ccaatctgtg gtaaatagtt gagttgctgc
    17221 cggaatatct tgttttttga caatcccttt ataaatattc accacttgat tatgtggctc
    17281 actattatag tactgataca accacccaat aatctctacc tgtccaccag cttgaacata
    17341 gaaatcatcc tctggaatac ttaaaagatc agcgattaca ccatcttttt taatataaga
    17401 agctgtaaac aaaagttctg tataatcttc tacttcttca aatagctcag gtaagtaatc
    17461 attcaattga ttacagattt ttataaaaat caattgatac agcttgtcca ttgcttctgc
    17521 tgaattatct gttttccaag ttctgacttg ttgctgttca ttactagata attcttcaaa
    17581 gatatcggca tcataaatat ctgtaataat atctggctca attttcccac ttatttcact
    17641 agataataca cgatacgtgt caggtaaata atcatttacc tccataaacc gaatggcaat
    17701 caatcggtta aaccacgtat aagcaacctc ttcgattaac tcttgaaaag cttctgaata
    17761 agaagtgaca gaagcacgtt gttttagttc tgcaatcaat ttgtttcttt gcgctatttc
    17821 ttttccttga attcttattc ctgatttttc gatttcttgt aaattgctat caattttctt
    17881 cacatcttca atttttgatt catcaattcc taaacgtttt gctttagtca ttacttcatc
    17941 aattaatttt ctacgggcat tgaccgcgaa attctttatc gctttcttat ccatttttct
    18001 ttcccttcta tatgtaacct ttgaaaagac aggcaccttt ttatgcctgt cttttcacta
    18061 gaattgaatc gtgatttctg tattttcttg aagttgttcc ttcagttttt gattaatttc
    18121 agctgttaac tcatcaatat ctgctgctga cttaatagtt ttaacatgaa cgttaagtgt
    18181 tctcattggt actgttttct gttgaatagt aggttttact atcgctattt cttcagcttt
    18241 tgctgcagag tctatttcat ctttttcagt ttcacgaatc aagtttgctg cttcaatttg
    18301 tttacgtgct tgttcttctt gacgtctgcg gttttcttca ttatcgaaac gttgattaaa
    18361 gatcaaatac tgttctgcta cgtttaatga taagaaaaca agatcatcta tagtattcgc
    18421 ttgttcaatt tttgctttca gttcttgaaa ttcttggtca actattggta caaattgatc
    18481 cttaaaatct tttccttcta ataatttaaa tgttgcttgt ttttcttccg ttaatttatt
    18541 taatatttcc tgactttcca actctaacag ttgattatat tgttcaataa attcttgaat
    18601 caactcattt agtttcatca tatctgaata aggatcagcc tttttcaaaa tggttttcat
    18661 ctcatgaatc aattgatcaa tttcttggct agaagtttga cgccgacttt tttcgattaa
    18721 tctaatttta tcttgtgcat tctcccagat ttttttctga gtactatttt gcttgtggaa
    18781 atttttaatt ttatcatatg tttcagccca gtcgaataat tcatcgcgat attttttgat
    18841 tgtataaaaa aagtcttcaa catctgacgt ttgaacaatt acttcaagat atttttttat
    18901 ttgctcatat tcataagcac tagggtaggt ataagtgttt tgtaaatcaa aataagagcg
    18961 taaattgtct aattgacctt ttaaatattt cttgaaattt tccattgtat gttcattgtt
    19021 attttcatca acaatattac gactttgaaa cagttctcta ccgatttcgt caaccaattt
    19081 ttttgctttt ggcgaaatca ccgcgcttgg ttcaattttt atcttttcac tttctcgtcg
    19141 tttttgaata atcattacaa tactatttgg atcatccatc cgtgaaattt gtacattgtt
    19201 ataaagtaaa tcaattttac cagacatgaa aagtttagcg atgcaccatt ccacatcaag
    19261 ttctgtgaat ccatacggtt gttttgtttc aaaacgatca cgaattgttt tcatcgtaat
    19321 cgttaggtga tttctctttt gatcattgat aaaattgaaa atttcctgaa ctgcttgctc
    19381 atttgatgga tcttcaataa tttcattttt gctttctttc actaaatata agatatcttc
    19441 tttttcttta ggcgcatcaa tttggtttaa tttatggtat acttcttcag ccattttctg
    19501 aagtgctgat tggaattttg ctttaaagtc ggagcctgtc agttgaattt ctgcaccgtt
    19561 atagaaaaat tttgcagatt tcaacagttc atttaattga tcgttgatac ttgcacttag
    19621 ttcctgtaat tcaccagatt tttccgaacg aatcgcgtca aagttcttta ctacactcga
    19681 ataagtcgtt gttaaataaa gattcattct agcatacatt gctatatcat ctttaaattc
    19741 tttatctgat ggcaattcta cgaataataa gttacgggaa ctcttaagcg caagttctgc
    19801 ctcttgacct gctaaatcag agtatggtga aataaaatta actgtcattt cagcatttcc
    19861 agcttgcttg tatggacgtt gatctaacac ttgtgcataa gtaaacgtat accggttttt
    19921 aaatttattt ccacctgaca tgcctaattt ttcataggca aaactatttc ggtctagaac
    19981 gccgtcaaaa attcgtttag atagttctac gatcaaatca ctatctgtaa tattttgatt
    20041 tttaatctca cgagtaattt cctgttcttc atcagtttgg aaaatataac tatctaagtt
    20101 cttccgcaca aagttttcct taattaaaag gtccaatgct tcttctactc gttttttagt
    20161 ttccaggcgg tcttcgttga tatttcttat catcaagctc gtaatatttt caacatttgg
    20221 tttgatggct tgatcaacat atttaatcat gaataaaatt cgtaagacat ttacgttaaa
    20281 gttatctata tcagttggtc tttgaatatg agaattattt gtagcttgtg taatcactcg
    20341 gctaattgct gtatcaatcc aacgttctaa cgagtaataa aactgatcta aagaaaccaa
    20401 actggttgta tcattttcct tatttcgttc agcggcttct ttaaacattg ctagtaatga
    20461 acgttcacca gacgataagt ttgatccttg atagctgtga ttacgaatct cggttagaat
    20521 ttgccccaat aaattgaatt gatagggaat aaatggataa acttctgcgt aattttcagc
    20581 atcttggaag agctttaatt caggactatc aacaaagagt aatttatttt tcaattctgt
    20641 ttgaacagtt tcaaattgta aggctaaaga atcattggca aactcttttt tcttcaaaat
    20701 acgttcttta attacttcat cggcatttgc tgaagataaa ctcacagttg tggcaaaacg
    20761 atccttgatc ttagaaaaat cattatcaga attgttatca aagtttgtta cgtgatcaat
    20821 cgcttcctga cttgtcacta atacccaagc cttaccttca caaattcgac ccaaatcttc
    20881 cacaacggtt tgtaactgca aagtcaactc acgattaccg ccgatatatt gtccgacctc
    20941 atcgactaga aaggcaatat gatggtctgc ttctttggaa tcaagatagc ttttaactag
    21001 atttgcaaag tcatcaatgc ttattaaata atttcctgat gctttttcta aaaaattatc
    21061 aatagcggct tcactcataa aatcgatttt aagtgccgct tctttgatat catcttggat
    21121 ccaatcaaac tcatggcgct cttcttgcca ttttgcccca ttaatctctt caaaagcagc
    21181 tttgaatgca tcaaactttt cttctttaat taaccgacgt tcaaaatctg ctagatgtgg
    21241 aatcgtgctt aatccttgca tttcgttaaa tacctttaaa aaaacattca cgattccgtt
    21301 tttgtctttt ttaccacctg catcactttt tgaatcaata ttaaacagaa taacatctgt
    21361 atttatttgt gagcaccgtt ccatcgttgc caaagtcagt ggatctttga ttttcccatc
    21421 ttctttgaag taatcaatgg ctttcttgtc atttatttct cgatttgcga gcaagtaaga
    21481 aataattttt aagaaatgag atttacctga accaaagaac ccctgaatcc aaacacccat
    21541 tttatctgtt ggtgtattga tactccgttg gtaggcatca aaaattgttt taaagtgttt
    21601 ttgtagttct ttcgtaacca cgtattcttc taattcttgt tgaacatttt catcctttgc
    21661 ttgaccgacc ttaataactc cttgaatatt tcggtcaatt ggttttgcaa aaatatcttt
    21721 aattagcatt taatctccta ccttccatcc caactaaatt ctaaatgctc gataataatt
    21781 atcatcttta ttggtattaa gaattgtcaa acttaattca tcatattccc ctggatacat
    21841 catcacaact ggtacgcgat caaatacctg atgcatttta tttaaaatag agtgcgctct
    21901 aattaatgga tataattcgc caattcctgt caggaacaca actgattttt ctggtgtatg
    21961 ggcatccaca tattcaaaaa atacattttc ttcctcaggt aaatccattt tcaataaacg
    22021 accaatgctt tccactaatt tttgtaaacc acgtcgttct tccatcttaa tcgctttttc
    22081 agtgaaaccg cgtttttcta gatactctaa cataatcaca tagagattat aaactttcac
    22141 ttcataatta tcaccaacag atgttccaga tatatcatta atataatctc ttacaattaa
    22201 ctcgtctttc ggatcgtagt caaagatata atagcctact tcattaccta aaccacgatt
    22261 caataaaaaa tcttcttttt gaattacttc attcaacttt tccaaatgct cttgaatcga
    22321 taatgacatt ataaaattcc tcccagtgct agtacaatat ctttacgatt cttgtcaact
    22381 aaccattgaa tcaatcgttt atctaataat atcggagtca ttcgtccata ttctttttcc
    22441 cctctgacta atcctgtttc aattagattc gtttgataag cggcaataag ccgtttaatc
    22501 gtataatctt tccattttga aatatcttct gaacttctcc gcttctctgt aaaaaaagaa
    22561 cggtaatcaa ctggtgttaa ttgcaaattt cctttacgta gattttcagc atatacctca
    22621 gtcataaatt cattaaaaag atcatcaatc ataaggatgg aaatcaaatt cactaacttt
    22681 tgattatcta tatttaactg attgaaaagt tgcaatccag cttcatccag ttgactaact
    22741 ctccttttca cgttctgata gatttctttt tgacggttac tgctcactgc aaaaaaaata
    22801 ttttcatgtt catttttctc tttaatttct atatctgtat atccttctag tcgtaattga
    22861 atatataact tgaactctga aaaccaaaag cgtttagaaa ctagaccagc agaatatttt
    22921 ttattcaata gattgcctcc taatcatcta taattcaata agtaaacaag tgttttttgc
    22981 tcatcgttag cattcatttt ttagtatcta ctatacaata catatttatt ata
//
LOCUS       DAMEEU010000050        22635 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.051, whole genome shotgun sequence.
ACCESSION   DAMEEU010000050 DAMEEU010000000
VERSION     DAMEEU010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22635)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22635)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22635
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.051"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(227..1114)
                     /locus_tag="PB779_001858"
     CDS             complement(227..1114)
                     /locus_tag="PB779_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0739379.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(1111..1980)
                     /locus_tag="PB779_001859"
     CDS             complement(1111..1980)
                     /locus_tag="PB779_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0739380.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(2117..3403)
                     /locus_tag="PB779_001860"
     CDS             complement(2117..3403)
                     /locus_tag="PB779_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0739381.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            3676..4254
                     /locus_tag="PB779_001861"
     CDS             3676..4254
                     /locus_tag="PB779_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HDE0739382.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            4254..5183
                     /locus_tag="PB779_001862"
     CDS             4254..5183
                     /locus_tag="PB779_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0739383.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            5180..6916
                     /locus_tag="PB779_001863"
     CDS             5180..6916
                     /locus_tag="PB779_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HDE0739384.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="PB779_001864"
     CDS             complement(6979..7815)
                     /gene="pheA"
                     /locus_tag="PB779_001864"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HDE0739385.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(7812..8321)
                     /locus_tag="PB779_001865"
     CDS             complement(7812..8321)
                     /locus_tag="PB779_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HDE0739386.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="PB779_001866"
     CDS             complement(8314..9609)
                     /gene="aroA"
                     /locus_tag="PB779_001866"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HDE0739387.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRSIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(9622..10713)
                     /locus_tag="PB779_001867"
     CDS             complement(9622..10713)
                     /locus_tag="PB779_001867"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HDE0739388.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="PB779_001868"
     CDS             complement(10730..11896)
                     /gene="aroC"
                     /locus_tag="PB779_001868"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HDE0739389.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="PB779_001869"
     CDS             complement(11898..12962)
                     /gene="aroB"
                     /locus_tag="PB779_001869"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HDE0739390.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="PB779_001870"
     CDS             complement(12995..14017)
                     /gene="aroF"
                     /locus_tag="PB779_001870"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HDE0739391.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(14676..15650)
                     /locus_tag="PB779_001871"
     CDS             complement(14676..15650)
                     /locus_tag="PB779_001871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HDE0739392.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(15631..17514)
                     /locus_tag="PB779_001872"
     CDS             complement(15631..17514)
                     /locus_tag="PB779_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 2"
                     /protein_id="HDE0739393.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETTSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(17532..19757)
                     /locus_tag="PB779_001873"
     CDS             complement(17532..19757)
                     /locus_tag="PB779_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HDE0739394.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEKKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            19872..20906
                     /locus_tag="PB779_001874"
     CDS             19872..20906
                     /locus_tag="PB779_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0739395.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(20973..21986)
                     /locus_tag="PB779_001875"
     CDS             complement(20973..21986)
                     /locus_tag="PB779_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0739396.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKQLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(22064..22252)
                     /locus_tag="PB779_001876"
     CDS             complement(22064..22252)
                     /locus_tag="PB779_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HDE0739397.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
BASE COUNT         6447 a         4863 c         4096 g         7229 t
ORIGIN      
        1 gacaatcagg acagtcatcg gcaatatagc agcaatcact tctttaaaat tttttagcat
       61 gtatcctcct cctttactct ttaagtttac cttaaaatga aagagttttc gagcacaaac
      121 ttaaaacgtt atcatttaat ttttctcaac ataaaataac acacgtccca aaagtatctt
      181 tttacttgga aaaatgactt tgaaggaacg cgcttattgt gtttttttat tttacagagc
      241 cgatcattcc ttgaacgaat tgcttttgca aaacaaaaaa tacgatggca gttggtaaag
      301 tagcgatgac taatccagcc atgatcattc catagtctgg tgtataggaa gcacccatag
      361 cagataaaac aagcggaacc gtccgtttat caggagattg caaagctact aagggccata
      421 aataattgtt ccagctactc atgaatgtga tgattgcagc cgcggcatag gtatttttag
      481 ccgtcggcat atacactcta aaaaaaatac ttagttcttt tagaccgtct aatcgagcgg
      541 cttctactag atcttttgga aaagatttaa cattttgtcg aaagaagaag atcaaaaaag
      601 cagtgctaac agatggcagg atgacaacca agaaactgtt gattcccaaa accgttccgt
      661 tcaattgtga aaacattcga tataaaggga tcatcaatgc cgcaaaagga accatcatcg
      721 atagcagtag aatattgaaa attaggtctt ttcgtttact ttgataaatc tcaaatccat
      781 atcctgccat tgacgaaatc agcaatgcaa acacagtggt caccaaagcg atcatcgctg
      841 aattccaaag ggaacgagta aaattcagct cattggaaaa caaattttga aaattgatga
      901 tcaagttact gccaatcttt atttttcccg atgtgatatc cacgggtgta ttcgtcattc
      961 ccaaaaccat ccagacaaaa gggaaaatgg aaataaatga taggatgctt aatgctgtat
     1021 actttaatac tgacccaatt gtcgaacgaa gttctaatgc ttgttttttg acgttggggc
     1081 gttcgattgt ttctttttct accatatttt tcatcgactt tctcctccta ctttcgtttg
     1141 gattatcgac aatatcacaa taaaggaaac aataacaaag gaaactgctg ccgcatatcc
     1201 aaaattaggc gtgaatttat aactcaaatt atagatgtat tgagataggg tggtcgttgc
     1261 atttgctggt cccccgccag taatattttg tacttcatca aaaagctgca atgtcccgat
     1321 cgtcgaagta atggaagtaa acaaaatgat tggttttaaa tttgggatcg tcactttgat
     1381 aaactgctgc catttagaag caccgtcaat agatgctgct tcataaatct ccgaatcaat
     1441 attttgcatg cctgaaagga aaaaaatcat attgtatcca gtccaacgcc aagtgatcga
     1501 aagaatgatc agaactctcg cccaaattgg atgagtcaac cagccaatcg gtgtgtcaat
     1561 cataccaatg cccaacaaca agttgtttac aaggccagat tgagaaaata gacttttcat
     1621 gatcagagaa taactgacca tcgaagtgat acatggaaga aagatagcgg ttcgaaacaa
     1681 ccctttatat ttcaactttt tatcatttaa aaggttggaa ataaaaagtg ctagaaacaa
     1741 catgatcggt acttgtacaa gtaaatacag gaatgtatta aaaaaagctt ttttaaaagt
     1801 tgcatctgtc aacatccgct gataattacc taacccgtta aatgtcatat tgacaggggg
     1861 accactttga aaagacgtga tcaaagccaa aaccatcgga ataaaaacca tgattgatat
     1921 caaaatgact ggcaagatta aaaaagcatg cccgtttttg aataaatctt tctgcttcat
     1981 tcttttccct ccaattctat cattgattat ctacatgaaa agacaagaaa gacaatatct
     2041 gtaaggcaga cgtgatcttt tttgtctttt cgtttgtctg atgaaaaagc gaagaaattc
     2101 acttttttac caccgatcaa ttagccaatt gtgcttctac ttgtttttgt gtatctgcta
     2161 gtaccttgtc tgtctcttct ccattgatga ttcgatgaag agcttcagct acgactgctt
     2221 caattgcata ggtctcatgt ccgtaattca cttctggtat ttcagatgtc catgttgaaa
     2281 aatcgtcaaa gatcttttga ccactgtaaa attcagaagc ttcttgataa gcttcttgtt
     2341 cattcgcgct aagcatcgta gatactagtc cgatttcttt cgcaagagtg cccatcagtt
     2401 cttcattcga agcaaacgtt gcttctagga aatctttcgc tgaatcttct ccagctactc
     2461 ctttgatcac ataccagcca gcgccgccaa ggttagaagc ttgcgctttt tgcagatttt
     2521 ctggaagtgc aggtattggt gcaatcttcc attttccaga ttggttttct gctccttgga
     2581 tcgttgaaga ataccaagcg ccagttgggc tagaagctac tgctcctgat tgtatcgcag
     2641 ttactccagc attccagtca gaggtttgtt cgactagatc ttctttcaaa agagtggcaa
     2701 acaattcaag accatacttt aaagatgcat tgtcttggat cgtgactgtc tccccatctt
     2761 cagatgtata ccattctcct gcctgttgca taatcatcct tactcgacca aggtcagaag
     2821 gattgacttc agcgattttc tttcccgtct tttctttgac atctcgcgct acttgaatat
     2881 actcgtccca cttcagattc tccatatcct cttctgtata acctgcttct gccatcagat
     2941 ccgtacgata gaagtttgct gttacgcccg aatcgaaagg aacaccgtat attttatctc
     3001 ctactttgtt taccgcaaat ttatacggtg caaaatgatc ttcctttaca atagcagaca
     3061 aattagcgaa tgcatctgga taagaagtca aatagccttg tatcctataa tcttcaatca
     3121 agacgatatt gggcaatcct tctgtattcc cgctcgctaa agcggtgttc agtttctgaa
     3181 cgatatcatc ctgagacatc gtaacaactt ctatctctgt ttcttcgttc tcataaactt
     3241 tttttgcttc attcactgct ttgatattga atgtctcatc ccacgcccag acagtgactt
     3301 tttcttcttt gtctgctgta ctactagcac ttccgcatcc tgttaagaaa cctgatgctg
     3361 ccgctaaaca aacgactcca gcaattaact ttctgatgtt catttttatc cgctcctttt
     3421 ccatccatta gttgtttacg tttgctacat tcatcatacc aaaatttgaa aacggtttct
     3481 ttattattca gatacttcaa aaatttctcc taaaataata aaaaaataca aatcaactat
     3541 gacaaaagga ataatcttag catctagacc aaagatcgaa atggtgaggt ttctttaaaa
     3601 taaaaatatc cttgcatttt ctcctagaaa taagtatttt taaattacaa gactattctt
     3661 aaggcgggta aaaaaatgcc aatacgcgta attcttatcg atgatgaaca gacgatttta
     3721 gatggaatga aacagttgat caattggtct gagcacgggt ttcaattaat agggactttt
     3781 tccagtccgc tgaaagcgct tgatttttct ttggtacatg caatcgatat cgtggtcaca
     3841 gatgtaatga tgcctgaatt aaatggaatc gaattatcgc ggctattaaa acagcaacaa
     3901 cctgaaacac agatccttat cctctctagc tatgatgaat ttgatatggt taaagattct
     3961 tttaaagaag gcgtcgctga ttatctttta aagcctcgat tgagtcctga tttttttcta
     4021 aattccttaa ctgccgtttc acaaaaaatc aaaaaaaagc ccaacaaaag cccaatcacc
     4081 aatcgttatg agcagatctg cgagaatctt tcacagcaga ttgctggaca aactcgtcca
     4141 ttgcttgacc ctcttctttt tgaacacacc ttgtttttct gttatatacc gaaaaacggc
     4201 cattcagttc aaaacaaggc tctaaacaaa aacagtcgat cacccattca ttgatggata
     4261 gcgacgattc gtttactatt tatcctgttt ctaccttttc ggaagaatcc ggctatgtaa
     4321 tcaatactga ttccaaagat acacttagga agtttgttca aaagtttcgt caagaagttt
     4381 ttccaggtga tttttttgtt gtttctgatt cttttgcaat ccaagatatc aatgaaatat
     4441 tccaagagat cagaaattgc accaaaggac aacgtttcta tcataaggga aagaaccttg
     4501 cttatcagca tgaacttctt ccgttattaa ccaaccacga gcagcaagca agtagttatt
     4561 taacaaaaat cgttcataaa gactacgctt tagctgtcaa agaacttgag aatttcttca
     4621 cgacgatatt ggaacagcct attgatccag cttatttgaa acatgaggca atcaatcgtt
     4681 tctatgcatt actcaacgct ttggctgacg agcatgttgg gaatgaagaa ctttctttgc
     4741 tcaagatcgc ccttccttct ttattagccg atgctgagta tttcgaagat ttttctattc
     4801 ttgtcaaaga aacacttgag aaactcaccc acttttctgc aaatgcaaaa aaagacaatt
     4861 tcgatatctt gactttgatc tacgagttcg tccaggaaaa ttatgagaaa gaaatcaatt
     4921 tacaactttt atccgaaaaa tatcattttt catatagcta tctctcagcc atctttactg
     4981 aaaaatttgg tatcaacttt tcaaaatatc taaaaaaagt ccgtatcagt aaagccaagc
     5041 tctttttgac ggaaacacgg cttactttga cggaaatctg tgagaaagtc ggctataccg
     5101 aactgggtta tttctccaga gtttttaaag aagagacagg aatgacacct tctcaatacc
     5161 gtaaaggaac ttttgtaaaa tgagaaaaaa aatcaaagag catgaactct ttgccaaact
     5221 tctgttcatt ttgttcatcg gtctttttct gcaagccatc gtcatttctt tgtttattta
     5281 tcatcgatca agggatgcct atatccagct gttcaatcaa tcgaatgatg tggtactaaa
     5341 aaagattcaa tctgaatttg aaagtttgaa tgatacaatc gagaatacat tagccgcttt
     5401 tgattctaat ccagctgtca aaagctattt ttccaatgat ccagcccaac atatggaaca
     5461 gcttcagcaa ctaagaacaa tccaaaaaat gaatgactct ctttcaaaaa tccatccaat
     5521 gatcgattac gatgtattga tctttggaga aaatggaaga acttttgtcg gaaacgacat
     5581 gctcactgcc gtatctgccg attctttttt tcaatctgcg attgctcaga gagtgaatga
     5641 acgtgctgct gatacacaaa tgctttttgc acaccacgga ttgactcttc gcgataagaa
     5701 agcacccagc gtcttctttg tcaaaaaact gaaaaataca ttgaatcacg tttacggata
     5761 tgctgtttta tcgatctcat ccaagcaact agcgaatctt tttcaatctg tagtaaatcc
     5821 tgagatatcg aagatctcct tcatgaacga agaacagacg atcatcgcat caaatgaaga
     5881 aaatacaatt gggagccgat caatgatttt caaaaaacta acagtaggtg aaacaacgat
     5941 ttcaaatgga cagcagttga cccgtcttcc tctgtaccgc caggattgta cattactcag
     6001 tcaagtcgat cttcattctt tatctaacca aatgggcgtg atttttccga ttattttgta
     6061 taatatcgtg acacttgctt ttgctggctc attggtattt atgtatttgg atcgacacac
     6121 aaaatcgatc taccgcttga ttgattcgct aaaacggcta gaggaagatg gcttaaaagc
     6181 tactgttcct gtacaaggaa gccatgaagt ccaattgcta gggaatacga tcaatcaatt
     6241 gctaagtaat gctcagcatc attatgaaca gacgatccaa gacgaaaaga agaaacgttc
     6301 gcttgaaatc caaactatgc aagcacagat acagccccat tttatttata atacgctgac
     6361 tagcttgaaa tttttgattt ggcagaaaaa aacagatgaa gcagttcaag gaatcgacag
     6421 tttcattact ttactaagaa gtacgattgg gaaaaaagaa gaagtgattc cagtcaagga
     6481 agaaatcaaa agcgtacaaa gttacatcga tcttttgagt atgcgatatg gcgaaagaat
     6541 ctcggctaaa ataatgattc ctgatgaact gcagtcatta tctatgccga atatgatcct
     6601 tcaaccaatt atcgaaaacg cctatcttca tgcttttcac aataaaacgc aaggattcat
     6661 cacggtgtac ggcaaaacaa aaaatcagct tcttttattc gaagtgattg ataacggcga
     6721 tggcttcgat actgaaaata ccaaacaaaa aaatgatcat ttttcaggaa tcggcatcag
     6781 ccatgtagat gagcggatac gcctaatgta tggcgatgca tatggcttaa cgatccaatc
     6841 agtgattggg acaggaacga ctgtaacgat ttgtctaccg cttcttccta aaaatcaatc
     6901 agaatatcaa aaataaagaa tagccaagcg ctgatttttt tattttaagt taaataaatc
     6961 aatcagtatt cttgactttc atctacgcgt ctcttctact gtcagcactg gataacagcc
     7021 caatatttga ctttctcctc cgagcatctt gatttcttgg agcgcattct ctactaatgt
     7081 cattggacgg tccaacaaca aatcgatcac gaaaaaatat tctcccaagc tagttttcaa
     7141 tggtcgggat tcaatcttac ttaagttgat ttcccgccag ccaaaagctg ccagcatttt
     7201 atgaagcatc cctggccgat tagcaggtag tgtcaagatg acactcattt ttactggagc
     7261 tgactgctgg ctggtcatct ttcggtcacc gacgatccaa aaacgtgtct ggttcaactc
     7321 attatcttgg atattctcag ctaagatctc caatccaaca tgctgtgctg tttctaatga
     7381 agcaatcgct gctgcgtctt ctttcggatg ttctgctaca tacattgctg cagcagttgt
     7441 tgattctgtt gctactaaag gaacattagg ataatgcgtt tctaaaaact gttgtgattg
     7501 tgctagtgct tgtggatgtg aaaggatttt tgtaatcttt gttgctggat tgcctaaaag
     7561 ctgctgcttg ataggaagaa cgatttcact tttaacttcg acttctggat gtttggaaag
     7621 aagatcgatt gtgtgatgaa cagctccttc caatgaattc tctacaggaa cgacagccag
     7681 atcgacttgt ttgcgaaaca aagcgcgcaa acaaacaggg atggaagcat acgcagtcaa
     7741 ttgttctgta ggaaatagct gacaagccgc ctgataagtg aatgaacttt ctggccctag
     7801 atagctgacg ttcatatgct tttgatcctt tctataatgg tatcgatgat cttttctggt
     7861 gtttgattgg tcgtgttgat tcgatgtgtc gcactttctt cataccaaga aagtcgttgt
     7921 gccaataatg cttttatttc ttctcttgtt tttccaagag ctaaaggtcg aatagacgtt
     7981 tcatcttgtt ggatacgatc aactagacag tccgcttctg cctctaagta aagaacaatc
     8041 ggctgtgttt ttaaaaaacg ccgattttct gcactttgga caatccctcc accagtcgcg
     8101 ataattttgt cttcatttga cagctttctt aaaatatctg actccacttt tcgaaagctt
     8161 ttttcaccgt aatagtgaaa atattcggca atcgacaatt ggatatgttc ctcaatcttt
     8221 gtatctaaat ctacatactc tttttgtaaa cattgagcta accctttacc gattgttgtt
     8281 tttccagcgc ccatgaaacc aatcagcaaa atgctagcca tgagcttctc ctcctgacac
     8341 aagttctgct aaatcgtcaa aaaatgccgg ataagagatt gaaacagctt cagctccttc
     8401 tagttcgcaa ggtccatcag ctatcaaagc agctacttgc agcatcatac cgattcgatg
     8461 atcgcctctg ctggacactt ttgcgccatg cagaggtgtc ggcccatgga tgatcagacc
     8521 gtctgctgtc gcttttatct ttgctcccat tttctgtaat tcttctgcca ccgcatcaat
     8581 tctgttggtt tcttttactt ttaattcttc tgcgtctttg atgatcgtga ttccttctgc
     8641 ttgagtagcc actaaagcta gaatgggcaa ttcatcaatc agacgcggaa tgatttctcc
     8701 accaatcgtt gctttcttca aatgactcgt cttgacactt aaatcagccg attggttctg
     8761 ttcattgtga ttcgtctggg taatcgctgc gcccatctcc tccaacacat ctaagatacc
     8821 agttcttgtt ggattgaccc cgacattttt taacaacagt tggctttccg gaacaagaag
     8881 tcctgctgct agaaagaaag cagctgatga aatatcacct ggaacagtta tctgttgacc
     8941 agttaatttt tgcggtccgg tcactatgat cgttttatct tccactgtga tccttccgcc
     9001 aaattgacga atcatttctt ccgtatggtt acgggaacgt tctttttcaa cgattacgga
     9061 tgtgccttct gcttgtaatg ccgcaaacag caaagcagat ttgacttgcg cactggctac
     9121 aggcatattg tatcggatag gtgataaaga gcgggttcct gtcacagtga ttggtagata
     9181 ctggtcattt tcttctcctt gcaagtcagc gcccatctcg cgtaaaggtt ccatcactcg
     9241 ccccattgga cgtttagaca acgaagcatc cccgaacaga gtagtcgtaa aaggctgtcc
     9301 agccaaaata cccatcaata aacgtatggt cgtaccggag tttcccatgt caattgattc
     9361 ggttggttgg acaaatgagt ggctaccgcg accatgaatc ttgatcacct cttcctcttc
     9421 ttcgatctcg acacctaatt gttggaaggc atgtaaagta ctcagacaat cttctgcgcg
     9481 caaaaaattt tgtatagtcg tcgttccttc agcaattgct ccaaacatga tgctgcgatg
     9541 ggaaattgat ttatctgctg gtatcctaac agtccctctt aatccatgta tttgttgtaa
     9601 taattgcatt tatccagcct cctatttgat ccagcaatga taactggtat tagacataat
     9661 gattcttttt gcttgtaaca aatcctgttg gtttttaaaa ctgatttgca gtattcctaa
     9721 aatatcttcc ctggtctctt ggatcttcaa attaatcaaa gaaactcccg cttttccgat
     9781 cagtccagtt acttctgcaa taacgccagg ttcatctggc acatcgataa ataaatcaaa
     9841 aaaggcagga atcgcgcctt gcttatggac aggcaactgg tctcgacttt cttttgcccg
     9901 attgaaaaaa gaaaagattt ccgattggtt ctcagtcatg atccattctg ctatttgtgt
     9961 catttcttgt tgccaatctg ccaatcgttc caataatatc tgcttattgc tcaacaaaat
    10021 atctgtccac atgacaggat ctgaggaagc gatcctagtg atatctcgaa agcctcctgc
    10081 tgccagttgt ttggctcgcg gatactcttg attgaattgt tctgcctgat tgactaagcc
    10141 agctgccaga atatgtggaa aatgacttag cattcctgtt atacggtcat gttctcttgc
    10201 tgtaagagtt acatattttg ctttggttcc gcaaaatagt tcttgcagtt tttcaacatc
    10261 ttttttcgtc ttttccaaag gtgtaaagat gtaataggca ttttcaaata gtttagcatc
    10321 tgctgcctgt atacctgatt tatgagaacc agccattgga tgtccaccga caaaccgaag
    10381 atttttctgc tcagcggatg tcacgacttg ctgcttcgta ctgctgacat ccgtaatgat
    10441 gacgtgatca gacaagttga ttctttcaag gacatcaaga taagctaagg ttgtacggac
    10501 gggaacggct aataagataa cgtctgcttg ttctgcacct gtttcaaaat cacttgcaac
    10561 gtaatcaacg atctgctgtt ctactgcttg ctcacgggtt tttgactgac tatcccaacc
    10621 aactactatc agttctggat tggtctgacg aatacaaagt gccatagaag caccaatcag
    10681 tccaagcccc acgataaaaa catgttgtgc catcttattt gccccctttt tagtaatgtt
    10741 tcaagtagtc acggtactcc ttcactgcag ctttcaactc aacaagcgaa tcacttggga
    10801 attttgacaa tagctctgtc gctaccacag tggctacaac attttccgca acgacgctag
    10861 ctgcaggaac tgctgtacta tccgaacgtt ctacacttgc tttgtaaggt tcttttgtat
    10921 cgatatcaac actttgaagt ggcttgtaca atgtaggaat gggtttcatg accccgcgaa
    10981 tgacaagtgg ttcgccattg gtcattccgc cttcgaagcc gcctagatta ttggtacgtc
    11041 ggaaatagcc tctttcttct tcccatagga tctcatccat cacttctgag cctggtaatg
    11101 aaccagaagt gaatccgacc ccaaattcta cgcctttaaa ggcattgata ctaaccacag
    11161 cttgtgcgat tttggcatct agcttcgtgt cccattgtac gtagcttcct aatccagctg
    11221 gaacgcctcc aacgagcact tctacaattc ctccgatcgt atctccattt ttctttgtct
    11281 gatcgatcaa atcttttatt ctttgctcaa ctgctggatc aacaactcgt acttctgacg
    11341 cttcagaaat ttctttgatt tcttgaatcg agatatttcc aggtatttct gcttggattc
    11401 caccaagaca aatcacgtgt cctgctacga tgatgtcaag ttcttccaga attttcttgg
    11461 caattgcgcc gattgctaca cgcatggtcg tctctcttgc agaggaccgt tcaagcacat
    11521 tccgaagatc tcgatgatgg tatttcatac cgcctaccaa atccgcgtgt cctggacgcg
    11581 gacgtgcaac tcgccgcagt gattggtctt tttcaggcac ttctgctaca gacatgacag
    11641 ttgtccaatt tttccaatct ttattttcta ccactaaagt gacaggtgaa ccaattgttt
    11701 tgccgtgacg gatgccagac gtgatccgaa cacgatcttt ttcgatcttc atccttcctc
    11761 ctctgccgta accagcttgt ctgcgagcga gttcgtgatt gatttcttct tctgacagag
    11821 gtaatcctgc tggtagtcct tcaataatgg ctgttaattc tggtccatgg gattctcccg
    11881 cagtcatata acgcatctta cagtcctcct aagtaatctt tgaatgtctc tgtgggaaca
    11941 ggaacgattt ttgcttgccc aatcttttct agcaagatga tattcaattg gcttcctctt
    12001 gctttcttat catgggttat cgcgtggaat aattcatctg gatgacttag atcgtacgta
    12061 atcggcagat ggaatttttg aagtatcctt tctaaagcag ctgtcgatcc agttggagac
    12121 aagccgattt tttctgcatg agaagtgatg gctaccattc caatagctac tccttctcca
    12181 tgactgacta ccccatatcc tgctgtattt tcaattgcat ggccaattgt atgaccaaaa
    12241 tttaaaataa gtcgatttcc ttggtcaaag acatcttctt ccactacttt tcgtttgatt
    12301 tccaacgtag cagtaatgat tggaacagca tgttccagaa gatctttttc gtctttcagc
    12361 tcgttcagct gtttccaaag cgttgcatct gctatagctg ctgatttgat gatttcagcg
    12421 attccttctc gtaaacgacg taccggcaaa gtttttagaa cctcaggatc aatcaataca
    12481 ccagctggct ggctaaatgt tccgacaagg tttttcgctt tgtttgtatt gactgctgtc
    12541 ttcccgccaa tactagaatc tacttgtgca agtagcgtag tcggaatttg aacgaaatgg
    12601 atcccacgca tgaacgtcga ggccacgaat gctgctagat cacccaccat tcctccacca
    12661 agtgcaagta tcccatcgct gcgggtaaaa tcattatctg ctaaaaaatc gtataactca
    12721 gctgcttgtt ctaaagattt actggtctca cccgccggta cgattgaaag gactggttca
    12781 aaattagctt gtctcaattg gaacatgatt ttttctgcat atagtggagc aacgtttgta
    12841 tcagtgatca cagctacttt ttgaggtctc caaatcgttt gaagccatga tccagcctgt
    12901 tctagtgcgc ctttttcaat atgaatatcg tatttttggt tatcaacatg tacagtaagc
    12961 attcgtttca cttctttctt ttaaaaagct ggaattaatc gagtgtctga atcttttcca
    13021 ttgcttcttt catgatcgca acttctttca tcatgcgtga gtaagtcttt tcattcaacg
    13081 attggggacc gtctgaccaa gcatttgcag gatcaggatg gatctctacg atcatgccat
    13141 ctgctccgct tgccacaccc gcacgagcca ttggtggtac aagttcccaa attcctgtac
    13201 catgacttgg atcaacaatc acagggaaat gagttaattt tttcatcaat gggacagcac
    13261 ttaaatcaaa cgtattacgt gtcgctgttt cgtaagtccg aatcccacgt tcgataaaaa
    13321 tgacaggaga tttgtcttcg actgcaatgt attctgcagc attaagccat tcattgatcg
    13381 taccggaaat tccacgtttc aatccaacag gtttacctgt tttaccgaca gcagatagca
    13441 gtttaaaatt ttgcatatta cgtgcgccaa tctgtaggat atcgctgtac tcagccacca
    13501 tatcgatatg cccttcatcc atcacttcag taatcacttt cattccaaat tcatcagccg
    13561 cttgacggat gtatttcaat ccttcttctt ctaaaccttg gaaagcatat ggagaagtac
    13621 gtggtttgaa ggcaccacct cgcagaattt ttgcgccccc ggctttggcc attcgcgcac
    13681 attctctgat ttggtctaat ccttcgatag aacaaggacc agccatcgtc acgaaactgc
    13741 cgtcaccaat ttttactccg tctacatcca cgactgtatt gccaggatgg aattctcgag
    13801 aagtcaattt gtatgtgttt aaaatacgca cagcattttc tactccttca tagcgtgtaa
    13861 atgctccttc ttgtaaactt cgcgtatcac cttttagtcc aatcactact cgttctgttc
    13921 cttgatcgat tgagactttg aatccttctt tttcgatatg atcgacgact ttttttattt
    13981 gttcttccgt tgcttctttt ttcataatta ctatcattgt ttttcccgct ttcttttgtt
    14041 tacttatcta tcttggctga ttttctctac tttttcaagg tggttttaca ttaattccta
    14101 ctaaatgacc gtgtcctgtt gttctcattt tcgctccttc tttcctactt atgacccaga
    14161 taatcaacaa aaaaagatgt ccctgtagga aattgcctct acagtgaaca tcttcaacga
    14221 gccttaaaaa gcgctgcaaa aatataaaat agccactata gatgaatttc tctacgtggc
    14281 tgtaagtcgt gtttaaaaat ctttagccat catagataca aacctggttt gtttgtaccc
    14341 acgaagtcat gaatacaaac ctatctaaaa tagctaaagt aatacgtatt cagttttgta
    14401 agttttctag atttcataaa aaatcgctcc aaactgatgt aagaattgta cctagtatag
    14461 acataaaaaa atcgactgtc aatcattttt atgaaacttt ttttaatttt ctgatagtta
    14521 actttgtttt tcagaaaaat aacaattggt tttattgaag aaaatagtca tgaacaaaag
    14581 tatctgagaa cttttttact ctcttgttca tgacatatag aataaagcag ctttgtcttg
    14641 taaactccgt ttttcaaata ataatctaaa gattgctact gaataataaa gccgatttca
    14701 tggtcctctt cgctgctgat tcggtaaggt gactcaacat ccgctcccca gctattgata
    14761 cccccgactc ctcttacttt tgcaaaaatc gtaagaaccg ttcgtctttc tggcggtagt
    14821 tcttctatat gtgttgcctg ttccagttct tctgctttga atggtaaagc ggaaaaagca
    14881 aatggcgtat cctgctgttc aaatcgcaac gaaaaatctt cttgatcttt atccgtatta
    14941 tccaacgttt gatttcttgt tagttctacc catttcgttt ccatatgcat gccgcattct
    15001 tggggaacaa ggtatgggga aacggggagt cctgccactt tataaatacc ttcgacacca
    15061 ccagccatcc gatccggata tgtttcccct gataggcctt catactcaaa aaattttgct
    15121 ttcgttggca taatgaacct taaacccaat gcgggtaatt ccggtaatcc tttttgtcca
    15181 taataatgca tattgacaag cattttaccc tctccagcga tttggtagga aattgtcact
    15241 tgggtttttg gtactgtgtt gatttccagt gtaaaaatga tttcaaccgt ttcagcgtat
    15301 tcattacttg aatattgatt atttactgga gcaatcggca aatcgatctt tttattgtcc
    15361 accagtactt ctatttcttt gacttttgga tacaatccgg ctcctaacca cataccggat
    15421 ttaaatccaa atccgctacc tctgtcatta tcggtcgttg ctcgccaaaa aactggaagt
    15481 gtttcccggt atagccattc ttttccgttt ttattgagcg attccagtcc gcctcttgta
    15541 taagaaaaaa tataatgcgt attccccgat ttgacaccta atgtacagtc gccgaagacg
    15601 attgcaactt tttccgtatc catatgactt ttatttactg tatttttcat aataatatct
    15661 tacctcctgc atggcgggtt tttcttgtcc atctgcaaaa acgatcccat tccctgagaa
    15721 ttcatagtca cttggtttat cgtcaaagtc accgccatag cgcatcactt ctctgcctgt
    15781 gattggatca gtcacttgga tcgcctgatc tttaaaatcc catatatagc ctccttggta
    15841 catttcataa cgatcaagca acgtcatgta agaatccatt ccacctaacg aattccccat
    15901 gtcatgcata tattcacata agatgaacgg tttttccgct ttattttcaa ggtagtcaat
    15961 gatctcttct ggtggcgcat acatgcagct ttttacatct gaaatcgaat cttcgaatgc
    16021 tggatttgga aaattccctt cataatggac aagtcgatcg gggtctactt ttttgaagta
    16081 atcgttcatt tgtcgaatgt tttcttccgc ataagattca tttccaagag accaaaaaag
    16141 aatacttgga tggtttttta atgtttcgaa attcgttttt gctcgatcaa gaacagccgc
    16201 ctgccactga ggtactgcac ctggtacgtt gtaagaaggc tcaaatgcgc ccattttttg
    16261 ccatgagcca tgggattcga ggttcgtttc cgccatcaca tggattcctg cttggtcgca
    16321 taaataatac caagtgatct ggttggggta atgagatgtc cgtacgccgt tgatctttgc
    16381 attttttatg atagccaaat ctttttccat atcttctata gtgatggcgc gtcctttttt
    16441 cggatgccac tcatgtcgat ttaccccgtt gataatcatc cgttttccat tgaagtagat
    16501 gattttatct ttgatttcga ttttacgaaa accgaaggaa tagtcaatat actccgttac
    16561 tcttttttct tcgtctatcg tctccaattc aagcttatat aaattgggct gaaaatgccc
    16621 ccacagtgcc acattttcaa atccatcgat gcgaatcgtc atttgctctt ttaacggata
    16681 ttgctgttga tagatttcct tcccatcagg atctagtatc gctacattca gctgactgtt
    16741 tttggctact tgctcaaaag acaaatctac ttcaagtttg ccattttgac atttgtcatc
    16801 taagcgaggt ttgatccaaa gatcttctaa atggttttgt cctcgagcaa ctaagaagac
    16861 atctctgaag atcccaaaaa atcggaaaaa gtcctgatct tccaagaatg cagctgtact
    16921 tcttttgtaa acctccacag ctagaatatt ttcttcttcc aaataaggtg ttaaatcaaa
    16981 ttcagacgga gtgaacgaat cttcggcata cccgataaaa tgaccattca accaaataaa
    17041 cattgcttgt tctacaccag caaaatgaat cgagatttgt tttcccttta gaccttcttc
    17101 taatcgaaaa gtcgtcaaat acgaaccaac cggattgtct ttagcagctg aaaagatccc
    17161 ttccgcctct ttctcagggc ttgtcgtgaa agggggacgg cgaaatacat gtccctccca
    17221 cggatacatc gtattgatgt aatggatctt gtcataattt gctaattcaa tatgactagg
    17281 aacagtgatt tcatcaaaag aacaggcatc aaaatctttt ttataaaatg tttttggtcg
    17341 taccgaagga tttggcgaat aacaaaaacg ccatgatcca tttaaagact gtttaaggga
    17401 ggatgtggtt tctacttctt cccttgttgc ataacaaaca tgatcgctat gtgcatttga
    17461 ttggttcact ctaaaaactt gtggatcatc taaccatttt atatttgctt tcatactttt
    17521 ttccttctct ctcataactt tttgaaatga agcagttctg tttggaaatc accttgaaaa
    17581 tcggggaagt aaagtccaac tgtcatcaat tcggcccccg aaaatatccg cttcgaggtc
    17641 tgttcctgat aaagtgcctc atcatctaac cccatcagat atacttcatg gaacgctggt
    17701 tgagctgaag ctagtatcct ccctaaaaac acaatagctt catcttgttt aggagacaca
    17761 aacatccatg cggcaatatt ttcttcaaaa ggactcgcca aacgataata atggccatac
    17821 tggatcaccg gacgaatcgt ttgataggat ataatttggt cttttacttg ctttttttct
    17881 tcaggagaca gctttgtcaa atccagttca taaccaaaaa cagcgctcat agctgtttct
    17941 cctcttgttt tcaacgaagt agatctgtcg gtctgatgat ttggtacagc tgatacatga
    18001 gctgtgatgg acgaaatcgg ataagcaagg cttgttccat attggatttt catacgctcc
    18061 actgcatccg tgttatcact tgtccatgac tgcggcatat aataaataaa cccggcatca
    18121 aaccgtccac ctccaccaga acagccttcc cataagattt ccggataatc agttgtcaaa
    18181 tgttcaagta gttcataaag cccgagcata taacgatgcg ctacttctcc ttgtctctgt
    18241 gggtcaaggg taatcgaata gacatctgaa agcgaacggt tcatatccca tttgatgtag
    18301 tcaagaggaa tcgtatctaa aatctttctc atttgtttct caatcgtctg ccgaacatct
    18361 aaccttgtaa aatccagtac atgttgtgat ctggaagcag aaggcattct acctggctcc
    18421 tgcataagaa aatcaggatg tgttcgatac agttcagaat caaccgagat catttcaggt
    18481 tcaaaccata aaccaaattt caatcctttg ctatgagcat aatctgctat ttcacgtaat
    18541 ccatttgtca acttgccttc atactcgaac cagtctccta atgaagaatt gtccgcatct
    18601 ctttttccaa accagccatc atctaatacg aacatttcga tgcctagctc ctttgcttca
    18661 tcaatgatcg ccttgatttt ttcactattg aagtcaaagt aagtggcttc ccagttattg
    18721 accagaatcg gccgttcagc aaattgatga cgacctcttg cgattctttc acgtagcaac
    18781 tcatggtgga tctgactcat tttgttcaat ccctgacttg agtaagaaag gatcatttca
    18841 ggtgtttgaa aagactggcc tgcattcaat tcccacgaaa aacgatggct gttgatccca
    18901 ccgacgactc tcaattgatt gatctgatct ttttcaagtt cgaaagaatg gttgccggaa
    18961 taaacaaatt gaagtccgat cgcttctcca gtattttctg tcgtatgatg atgaactaaa
    19021 gcaataaagt tattcatatg gtgactgctc gttcctcgac ggctttcaaa tacttttgtt
    19081 ccagataaaa cagattgccg tgaaatctgt ctttcattga catgtgctcc tggcaaagca
    19141 atgacttcat caaatcgcct agtatgggca aagtctagct ggaaactagc cgctttttct
    19201 agtttgattg tttctccggt ttcatttctt atctttacag atcgtgtgat cactgctcta
    19261 tcagtaaata tggtatagaa caaatcgaaa taaatcgctg tttctctatc cttaagtgaa
    19321 atcaccaacg tttgtgcctc tgacttgtcc atcacataag tttgaggcaa gccttcgatc
    19381 tctggcttcc catctgtaat ataatggctg tcatatctca gatccagtaa gtctgatcca
    19441 ttcttgcgct gaatgatcga tgcgggcgtt cgaaagtcca tgctgccatg agaagagtat
    19501 tcttgcggta gtgtatcttt cgacagagac cggtcaggat ttaagggaac atttcctgaa
    19561 aatccacgat ctcttcgggg ataattttta ttgtctttgt actgcttgac tggtttgcca
    19621 aaataaatat gcgccaatac attgctttct tctatcttta tcagataaga aagaaatgta
    19681 tttcgtaaat ggaagactcg gctcttttca tcaaataaga tgaaattttt atctgttttt
    19741 ctatgcgtaa tatccatcat ttcactccca acaaaacgga aaccgtttac ttttttttat
    19801 aattcctgta tactgtttac taaacaattt tgtcaataaa aattttttat ttttttgagg
    19861 agtgtgtaaa aatggttgga attagagatg tcgcacgaaa ggcaaatgtc tctcctgcta
    19921 cagtttcccg tgtgttgaat aacgatcaga cgatccatgt ggctcagact actcggcaac
    19981 ggatagtaga ggcagctgct gcgttggatt atgacatcag tactcgtaaa tatatcaaaa
    20041 agagaatgcc ttcgattggt gtgatctcta cgatcggcaa agcgagcgaa gaacaggata
    20101 tctattacaa acatttgcga gtagggatgg aagaagaagc tcgacgtctg catttaggga
    20161 tgaatcgaat ctataatcta tctgataatc ctaaacaatg ggaagatcta gatcagttag
    20221 gtgcggtgat cgttgttggg actgttacga aagaatcgat taccgccttg ttaaaacaaa
    20281 acatgcaaat agtcgtcgtg gataaccctg acatccagca agaggtcgat atggtgtatg
    20341 cagatcttga acggatgact aaaaccgtac tggaattgtt cttagaaaat ggtcataaaa
    20401 gaatagccta tatcggggga tataaagtcg atatggatga attcggtggg aagcagattt
    20461 ctataaatga aaagaggatg cgtgcctatc agcattttat gatcgatcat cacttagaaa
    20521 aatatatgtc ttatcatcta ggtggctgga cagaaaaaca aggtgaggta cttgcgacta
    20581 atctattaga aaatgaatcc cctcttccta ctgccattct tgtcgggagc gatccaatgg
    20641 caattggtgt ctatcgggca ttgaaacaaa aaaatatcca aattggagaa gagattgttg
    20701 tagcaagctt tgataatatc gagacaatcg caaacctctc ccctggcttg accagtgttc
    20761 aaatcaatgc gaaatcaatt gggcaagcag ctgttcgaat ggcattggag cgaattgacg
    20821 gtatacggga cgaaccaatc attttgactt atcctgcacg attgattgtt agggaaagtt
    20881 ttatcccaag aacaaaaagg tattgaaaga gaggttgtga aaagccgctt cgtttcttca
    20941 tactcaaaac gaaacggctt tttcacaacc tcttacttat acttattcac aaaatccaat
    21001 gtctgctggt aacaattttg cgattctttt agcgtgtaat caaattggta ttcatgggta
    21061 atctcttttt ttgtatctgt ataaaacaag gattgcacgg gtacctttaa ttctgtcaac
    21121 cgattttcta atgcttgacc ttgctcctgg aatgagtatg catttccgtc agttatatac
    21181 gttggcggaa attccttaga aacatggtca gccacactag cttctttcaa ttgctcactc
    21241 gttttccaat cttttgttcc aatcaacgac cacgcaacgg ttttgacgaa aaacttcata
    21301 aatcgatcat ccgaatgctg ctgtgctgtt agcttcaaat caacaggtcc gcaataagaa
    21361 atggttcctt tcagactatc ttttggaagt agctgtttga ttttcatttg tttagcatac
    21421 gcatcattcg tttgtatagc tgcatattgc aatgcgattt gtgaacctgc actatctcca
    21481 ccaaaaaata attgttccat gtctagcaat ttgtcgtctt tttcttcagc taataaatct
    21541 ttgatcagtt cattcacttg aagaacttga ttagggtatt ctgaatcagg cgctaattca
    21601 taattcatcg caaccactgc gatgttggcg tctgaaacta attttgtcgc aaattctttg
    21661 acacccgatt tatctccgcc gacgaatcct ccaccatgta cccaaaatag aacaggaaca
    21721 ggccccttgc tgttttttgg atagtagatg tcataagtat tctctttata cttggactca
    21781 tacgtcaaat ctgttttttt cgccacgttt ttttctgctt gatcgaacgt ttttttatca
    21841 gtgatttgaa cagtatttga aaacatatgg ttgatcaaga atgctccagg tctgggggaa
    21901 agctggaagg caagaaagat tgcaaacgcg atcccaagaa tgattccgaa gaaccatccg
    21961 ataaatttaa gaattttctt tttcataagg ctccctcagt agttagtatt aagcattctg
    22021 attataccat agtgttattt cctatcaagc tctcctagat gatttaatga ttttccccaa
    22081 acttcttctg caatgctttt gacaaaagaa attttttcca ttgttcttca aacaaaacat
    22141 tttcttcttc tgttgaagca aatccacatt gaggacttaa gcacaaacga tccaaaggca
    22201 gatatcgtgt cgcttcgtag atccggtcaa tcacttgctg gtgctcttcc atttcgccat
    22261 ttttcgttac agtcaaaatc taagacaact aatttatctt cagagacttt ctctaaaaga
    22321 acaaaactcc cagcacgttc actatcgtat tctaaataat aggcacggac attttcttga
    22381 gtaaaataat gggtctgcta cgtcgtcatc ccccctgatg ccgccaaaat cgaataataa
    22441 tttccgcgtc aaacatgtat atttagtgtt gaatcatttg agaatatgaa aataaaaatc
    22501 tttttgatca atcagttaat caaattgaaa taacgaaaaa tctgagacag aatgacgttc
    22561 attctgaccc agatttgatt ttgcacaact caacagtcct tattggcaaa tcgccaaaat
    22621 aatgtagact aacta
//
LOCUS       DAMEEU010000051        22043 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.052, whole genome shotgun sequence.
ACCESSION   DAMEEU010000051 DAMEEU010000000
VERSION     DAMEEU010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 22043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22043
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.052"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(30..398)
                     /locus_tag="PB779_001877"
     CDS             complement(30..398)
                     /locus_tag="PB779_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HDE0739398.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            569..1525
                     /locus_tag="PB779_001878"
     CDS             569..1525
                     /locus_tag="PB779_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDE0739399.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            1598..1714
                     /locus_tag="PB779_001879"
     CDS             1598..1714
                     /locus_tag="PB779_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HDE0739400.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(1769..3451)
                     /gene="recN"
                     /locus_tag="PB779_001880"
     CDS             complement(1769..3451)
                     /gene="recN"
                     /locus_tag="PB779_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HDE0739401.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(3469..3918)
                     /locus_tag="PB779_001881"
     CDS             complement(3469..3918)
                     /locus_tag="PB779_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HDE0739402.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            complement(4025..4843)
                     /locus_tag="PB779_001882"
     CDS             complement(4025..4843)
                     /locus_tag="PB779_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HDE0739403.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            complement(4852..5742)
                     /locus_tag="PB779_001883"
     CDS             complement(4852..5742)
                     /locus_tag="PB779_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDE0739404.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            complement(5744..5968)
                     /locus_tag="PB779_001884"
     CDS             complement(5744..5968)
                     /locus_tag="PB779_001884"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HDE0739405.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            complement(5973..7310)
                     /locus_tag="PB779_001885"
     CDS             complement(5973..7310)
                     /locus_tag="PB779_001885"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HDE0739406.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            complement(7311..8165)
                     /locus_tag="PB779_001886"
     CDS             complement(7311..8165)
                     /locus_tag="PB779_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HDE0739407.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            complement(8262..8711)
                     /gene="nusB"
                     /locus_tag="PB779_001887"
     CDS             complement(8262..8711)
                     /gene="nusB"
                     /locus_tag="PB779_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HDE0739408.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            complement(8704..9129)
                     /locus_tag="PB779_001888"
     CDS             complement(8704..9129)
                     /locus_tag="PB779_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDE0739409.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            complement(9375..10439)
                     /locus_tag="PB779_001889"
     CDS             complement(9375..10439)
                     /locus_tag="PB779_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HDE0739410.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            complement(10611..10856)
                     /locus_tag="PB779_001890"
     CDS             complement(10611..10856)
                     /locus_tag="PB779_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDE0739411.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            complement(10995..11369)
                     /locus_tag="PB779_001891"
     CDS             complement(10995..11369)
                     /locus_tag="PB779_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HDE0739412.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGNNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            complement(11452..12366)
                     /locus_tag="PB779_001892"
     CDS             complement(11452..12366)
                     /locus_tag="PB779_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HDE0739413.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            complement(12387..13190)
                     /locus_tag="PB779_001893"
     CDS             complement(12387..13190)
                     /locus_tag="PB779_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HDE0739414.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            complement(13223..14212)
                     /gene="manX"
                     /locus_tag="PB779_001894"
     CDS             complement(13223..14212)
                     /gene="manX"
                     /locus_tag="PB779_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HDE0739415.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            complement(14315..14806)
                     /locus_tag="PB779_001895"
     CDS             complement(14315..14806)
                     /locus_tag="PB779_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739416.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            complement(14997..17804)
                     /locus_tag="PB779_001896"
     CDS             complement(14997..17804)
                     /locus_tag="PB779_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDE0739417.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            complement(18238..18531)
                     /gene="rpmA"
                     /locus_tag="PB779_001897"
     CDS             complement(18238..18531)
                     /gene="rpmA"
                     /locus_tag="PB779_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HDE0739418.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
     gene            complement(18544..18888)
                     /locus_tag="PB779_001898"
     CDS             complement(18544..18888)
                     /locus_tag="PB779_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HDE0739419.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            complement(18915..19223)
                     /gene="rplU"
                     /locus_tag="PB779_001899"
     CDS             complement(18915..19223)
                     /gene="rplU"
                     /locus_tag="PB779_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HDE0739420.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     misc_feature    complement(19243..19319)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            19505..20146
                     /locus_tag="PB779_001900"
     CDS             19505..20146
                     /locus_tag="PB779_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDE0739421.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     gene            complement(20208..21839)
                     /locus_tag="PB779_001901"
     CDS             complement(20208..21839)
                     /locus_tag="PB779_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HDE0739422.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(21962..>22043)
                     /locus_tag="PB779_001902"
     CDS             complement(21962..>22043)
                     /locus_tag="PB779_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HDE0739423.1"
                     /translation="GSLTSDRWILLKQGGLALLALLSIFL"
BASE COUNT         6415 a         4858 c         3670 g         7100 t
ORIGIN      
        1 aaagactttt tacagctttt ctattttttt cataggtaag aaagtatgtt cacaatgatc
       61 aagacagcgt acaagacgat tgtcaacaga aaaaccaaac gccaagtcat cttgaaataa
      121 cgcggataaa taatttcttc ataataatat gcttggaaaa cagcaataca aattcccatt
      181 agcaaaacag aaataaagaa aaacggtaag atagaaattg tccctgtatt tctagacaat
      241 gcatgcatac cgccccacaa aaaaggaatc gccaaatcag gggcttttat tttaaaacga
      301 cgatttaacg aaaataattt tacaagaaat tggcaaccaa acaaaacgat taccgggtaa
      361 atataccaaa acaagataag tggtgtgaat gtgcccatga acgtaaactc cttttttatc
      421 gttgcttcaa gtatactgta tatactttac acaactgttt cattttattt aaatttatgc
      481 agttatattc tatatcttac aaacacattc catgtattcc aattccctat ccgttataat
      541 aaaagaaaca ggcaacagga ggaaaatcat gatcaaatat tttacattag ataatgagaa
      601 actgcgtaat accggaaagg aaactgacca aacgatctgg tattgtgtag aacgtcctaa
      661 tcaagaagag attcatcagc tgacacatca atttgaaatt ccgtcagatt acatcacttc
      721 catattggac gatgcagaaa attcccgtac agaagaattc aatcaatcaa agttgacaaa
      781 gccagcgtta ttattgttac aatatccttt tgctaaaaca agtcctagcg gttattttca
      841 agtggataca tacccgctct ctattatttt gacgcccaaa aagaagctta tcacaattac
      901 gaatcatgaa ccactgtttt taaagaaagt ctttagccag acctttccaa aaagtgatat
      961 ttcgcctaat ctcaatatct tctttcaatt catttggcag gtcacactct cttacaacag
     1021 ttatttagct acgcttcaat ctcaatgcga tactttggaa gccaaacttc aagtatccac
     1081 tgaaaacaaa caactttatc aaatcatgga tatccaaaaa agcctcgttt atttcagaga
     1141 agcgacttct gctaatttag atgcattgaa agaactagcg caaaataaac ttttccaaga
     1201 aaatcatgct ttgaaaaatc atttacgtga tgtattggtg gaaacagagc aggcaatgac
     1261 tacttctcgc attcaattaa aactagtaga acaaatgaat cagacttttt cagcaatcgt
     1321 atcgaataat ctgaataata ttatgaaaat tttaacttct ttaacgatta ttttaactat
     1381 accgacaatc gtcggcagta tctatggaat gaacattaag ttacctattg ctgaaaggga
     1441 tgatgccttt atatggctag ttctattaac attatttatt tgtatcgtaa ctacctatta
     1501 tttaaaaaaa gggaagtttt tataaaaaag ccctcttgtg gaaatggaaa aaagattgta
     1561 cacttgaatc aactaattaa tgacgaggtt gaaaacaatg cgtgaaaaaa aacaaacaag
     1621 tacttttgct aaagtaacaa aatttgtcat ttggacaatg ctgattttaa cgattggatc
     1681 tgttgtattg actgctgtaa tgagtgtcat gtaaaaataa aatatagcta tcagctgctg
     1741 aaaaggacct gaaccactgc gaggtggctc aggtcctttt tgcgagtttc aatagttctt
     1801 ttgcatgttc gagtgtgagt tttgtaatct cacttccagc cagcatacgt gcaatttctt
     1861 cttctctttc ttttgttttc aactctgaaa cagaagtttg cgtacgtcca tcaatcactg
     1921 ctttcacaat ataatattga tagtcggcga ctgcagcaac ttgaggcaga tgagtgatgc
     1981 acaaaacttg agagtatttc gatatttgag aaattttatc tgcgatggcc tgtgcaactc
     2041 ttccgctcac acctgtatcc acttcatcaa aaataatact tgtcacacct tgctcagaag
     2101 aaaaaatagt tttcaaagca agcaacatcc gagacagttc gccaccagaa gcgactttca
     2161 ccaaaggctt cagtggctct cctggattgg tcgtaatgta aaattcgatt tggtcaaatc
     2221 catcatgatt caattgtcta ttttcttctt ttaagaaacg tacctcaaac tcagtgtttt
     2281 ccatatacag acttttcaat tcatgcagaa tggatttttc caattctttt gcgatttttt
     2341 tacgcgcttc atgaagatct gcggcttgtt gctgaagtag aagctctttt tgctctagtt
     2401 cctctttcat tttgtccaat tgaccttctg aaaaatcaga agaagctagc tcttcggtga
     2461 tttcgtcata gtaagccaat attgactcaa tggattcgcc gtatttacgt ttcaactgtc
     2521 ggattaattc taaacgttgc gtaacttctt ctaaacgact ctcatctaac tccaataaat
     2581 caatctgacg actcatatcg ccgattgcat cttgcagcaa atagtaagca ctttggatat
     2641 tttcataaat tgcttcatac tccacatcta gatgggcgat cccttgcagt tctgaaacgg
     2701 ccaagccaac accatctaca ctgttttgtt cattattcgt cagtgctccg taacctgcag
     2761 ctaatccatc agcaattttt tgataattgc taagtttttc tctttcttct tttaatttct
     2821 cttcttctcc gacttgcaaa tcagcagcag ctatttcttc ttgctggaaa tggagcatat
     2881 ctattctctg aacataggat ttttcatttt gctgcacttt tcgtaccctt ttttccagct
     2941 cacgataaga gatatattct tgctgataac tctttttctt ctgttggaaa gctacatctc
     3001 caaaacgatc caataaagca agatgtgatt caggctggag cagttcctga tgttcgtttt
     3061 gtccttggat atctactaaa taactgccga ttcttctcag attagctaat gtgataatat
     3121 gaccattcac tcgacaaaca ttttttccag ttaaggacat atcccgtcga acaatcagat
     3181 tgtcctcatc tgtttcgatc cctaattcaa ccatcagttc agagaatcct tcttgttttg
     3241 gtagttcaaa caacccttca agcacacatt tttctgctcc ttgacgtata taatcgcttg
     3301 aacctcttcc tcctgctaac agacctaaag catcgataat aatggattta cccgcaccag
     3361 tctctccggt cagcgcggtc attccttcgt gaaaagaaag ccgcaattcc ggaataatcg
     3421 caaagttagt aatactgatt tcttgtagca tcacattcgc tcctcaactt aaaggtaatg
     3481 caggaagtct ttcttcaata aaactgcctg gtcttcagtt cgtgtaatca tcaaaacatt
     3541 atcgtcatca ttgataatcg aaaataattc tttcttgtaa cgtttatcaa tcaaatttgc
     3601 tgctgccgaa gcatttcccg gcaatgtttt caaaataaca aatttttcca tttggtcaac
     3661 tgccacgaaa gcgtctttta atagtttttc caatttagta tttacatctt cgtttgtttc
     3721 agctggtatg ctataacggt agccgccatc tgaagccggt accttgatca gtttcagttc
     3781 ctttatatct ctggaaatcg tagcttgagt aacagatatt cctttgcttt tcaggatttc
     3841 aacaaattct tcctgctttc ggatatcttg ctcactcaac aatcgagtaa tcaaacgatg
     3901 ccgatctttt tttctcatta cgtcttcgct ccttagcata ttcttcttaa tcaatgatag
     3961 cttatttcct tggtataata aagaagaatc cgcatacttc tcacttgatt ttcacagtta
     4021 caatttattt atggtcaaac tgttcgtgtg catttgaaac cacttctgcc atattaatag
     4081 ctgaattgat tgttccgctt tcgggtactt tcctcaagtg agccaagaac tcgatatttc
     4141 cttctccccc cgtgatcgga gaataactta attccagcac atcatatcca ccttgtgccg
     4201 caaatgacaa aatgtcttct aaaacttttt gatgggtctg agggtcacga acaattccgt
     4261 ttttccctac agcttctctg cctgcttcga attggggttt gattaaagca atcacttctc
     4321 cctcttcttt taaaatagca tgtaatggag gcagcatcag ttttagtgaa ataaaagaaa
     4381 catcgataac agcaacttct ggaattccta aggtaaagtc ttcgggtttt gcataacgaa
     4441 aattcactct ttccattacg acgactctag gatcttgtct tattttccaa gctagctgat
     4501 tgtagccaac gtctaaagca taactcattt ttgcgccatt ttgcaaagct gcatcagtaa
     4561 atccgccagt ggatgcacca atatctaaca atgtttttcc ttcaacagat agatcaaatg
     4621 ctttgagtgc tttttctaat tttaatcccc ctcgagaaac ataaggaagt tttttacctt
     4681 tgactcttaa ttcactactc actggaattt tttctcccgg tttatcaaac cgctcgtttt
     4741 tttcgttgta aatcaaacca gccatcactg aacgtttggc ttgttctctt gtttcaaata
     4801 atccttgttt gaccgctaat acatctacgc gttctttttc cattctttcc ctcatttctc
     4861 cacatcaaat tgcttgatca tctggcgcat cagcccgcca tcaaaagaaa aaacgtcctc
     4921 ttctaatttg tctatgatct tgttggcgga taacagctca atctccaacg cctcacgtgt
     4981 cttttctagg cctaataaac gcgggtaagt atttttttcc atacgttcat ctttaccagc
     5041 tgttttccct aatgttttcg ttgtaccaat cacatcgagt agatcatctc ttatctgaaa
     5101 agctaaacct aaatgttcgg ctaatcgttg aagtagcaat aagatttctt caggttgctt
     5161 cgctaatatg ccaccagcca gcaaggcata acgaatcaaa tgccctgtct ttctttcatg
     5221 aataaatgct aattcttcta aagaaagctt tttcgattcg ccctcgatat ctgcagcttg
     5281 cccagcaacc ataccttgtg atcccgcaca aacagctaat tgctgaagca gcagaagctt
     5341 aggagaatta cctaagtgtg ccatactgat tagctggaat gctcctgtaa gcaaaccatc
     5401 tccggccaat atagctaatg cttcgccgaa tactttatga ttggtaggtt ttcctctacg
     5461 aagatcatca ttgtccatcg caggcaaatc atcgtggatc aaggaatacg tatgcaccat
     5521 ttctaaagca gctgctactt gatagacggg aacatcaata ggctcatcaa aggaagcaac
     5581 ggccgttaaa agtaataagg gacgtattct tttcccgcct gctttcactg aataactcat
     5641 cgcatcatag agtcctctat ccgttgtatg ctcatctaaa aaagacaaga tttctttttc
     5701 tacagcaggt agatgaatag ctgaaaagtc agttaatctc atctcagctt tcctcgtttc
     5761 cgtcaaaatc aacttcttca tttgattctg tcatcatttt cgtcaaggtc tcttctgctt
     5821 tagctaatgt atcttggcaa tgtttgctta attccattcc tcgtttaaac gaatctagag
     5881 ctgattctaa tggaacgtct ccttgttcta actgcatgac aattttttct aattcttgca
     5941 gtgactcttc aaaagttgga ttttccatat ttttattctc ctttgtctat ctcttgtact
     6001 tgtcctttaa cgattccatc ttgataatgg atcgtcagca aatccccttg atgaatctcg
     6061 gtgacacttt ttactacttg atcatttaac gtcgtatagc tgtagcctct tcccatgatt
     6121 ttcaatggac tcaacaaatc aagagattga acagcttgag caaaacgctg ctgctgttgt
     6181 ttcatatatt gttggatttt ctcttctaag cgtttttcta gataagcagt ttcttggcga
     6241 gctgctttaa ctcgataaag cggagccact tgttccaatt ggtggcttaa tgcgatcgtt
     6301 tgtttttctt tcgcatgata aatttgctgt gtagcttgat ataatcgctg tttcaactgg
     6361 tctaatttga tggtctgacc ttcatacaat ctttcaggct gccgaaatac ataggaacgt
     6421 cgagcacgct cgaaccgttc ttgtttgcgc tggatctggc gtacaaacgc ctgctgcaat
     6481 ctagcttgcc gttcttgaat gcgcatcaac tcttctgaca aaacaggaac agctaattct
     6541 gcagctgctg ttggagtggc agcccgaaca tctgctacta aatcagcgat cgtggtatct
     6601 gtttcatgtc ctacagatga aatcaccggc gtattagctt gataaatcgc ccgagcaacc
     6661 cgctcttcat taaacggcca taaatcctca atcgaaccac ccccacgacc gatgatcatt
     6721 gtatcgaaat tgcccatctc ttctactctc tggatattcc tgacaacatt gtccgctgct
     6781 tggtttcctt gtacaactgt tgggaacaaa accaattgga caattggata tcttcttttc
     6841 accgtcgtga tgatatcgcg gataaccgct ccgcttggac tggtaaggac cgcgattcgc
     6901 tttgggaaac gtggcagcat ttttttaggc ccttgaaaaa ggccttcctt catcagcttt
     6961 tcttttcgtt cttccaattc ttgatataaa gcacctattc catcaggctc catgtgctct
     7021 acatagattt gataagaacc tcccgcttca tataatgaaa tacgcccaac gacaaggact
     7081 ttcattcctt cttttggctg gaatcgtaat ttttggaatg ctcctttgaa cataatagca
     7141 gatatttttg catggtcatc ttttaagctg aaatattgat gggcattggc acgtaaacgg
     7201 aaattcgata tttcgcctgt taaatatacg cgttctaaat aaggatcggc atcaaatttt
     7261 cttttcaaat acttcgttaa tgtagtgaca gttaaatatt cttgtgccat ctattcacct
     7321 gctccaaaag cttcggcaga ttttacggtt tgatacatca gcatcgtgat agtcattggc
     7381 cctacaccct ttggcacagg agtgatccag cctgcaatag gctccacttc atcaaatttc
     7441 acatcaccga tcagcttacc gttagcatca cgattcatcc ctacatctat cactacagca
     7501 cctggtttta cgaattcttt tgtgacaaaa tgtccacgtc ctattgctac gactaaaata
     7561 tctgcttctt gtgccagttc agccagattt tcggttttag aatgagcaac agtaacagtt
     7621 gcatctgcca tcaagagtag ctgagccatc ggtttaccga cgatattgct tcgtccgata
     7681 actactgctc gtttacccgc cggatcgata gaataagctt caaacatttt catgatgccg
     7741 tatggagtac aaggaatctt gtccggttta cccgcaagga gtctgcctaa attcatcgga
     7801 tgaaaaccgt ctacgtcttt ttcagggcgg atagctaaca ggatcttttc ttcatctata
     7861 tgctttggca atggtaattg gaccaatata ccatgaaaac taggatcttg attgtatttt
     7921 tcaatttctg caagtagttc gtcttcagaa atcgtctcag gataacgctc taccaatgaa
     7981 tggattccga tttcttttgc tacacgttct ttatttctta catagatttg gctggctgga
     8041 ttttccccta ccaataaaac gactaatccg ggatggatac cattatcttt caatttttgg
     8101 attttttcag caatctctgc ctgcattttt tcagctaatt cttttccgtt aatcaattct
     8161 gccatctaac cactcccaga tattttttgt gttttcattc taccatagaa ttttcccgat
     8221 ttataacagg tttatgatga ttcatagaaa aaagctagga cttacgcccc agcttctaat
     8281 tctttcaata cattggataa aacaccgttg acgaatttac gtgaacggtc atcactaaat
     8341 gtttttgcca actcgattgc ttcatttaaa gcaacagccg ctggtacatc tgtcacataa
     8401 gtcatttcaa aaatcgcgat acgcaagatc accaaatcca tttttgagat ccgattgatg
     8461 tgccaattgt tttttaaatg tttttcaatc actttatcca attcatcttt ttttgcacag
     8521 acaccgccaa ctagcgtatc aagataaaca ggaacaaact ctgattcatc ttcgttgatc
     8581 atgtcgcggt ggtctaattc gattgcgttg aaaatcgcat cttcttttgt taggtctgca
     8641 ttgaagtcta atggaaataa agcctgcaat gccatttccc gaatctcgtg tcttgataat
     8701 tctttattca ttctcttcct cttcgtcttc aaaaagttct tcgattgttg gttgttctaa
     8761 tttttcagga acaacagcta ctacatggat attgacttca gataaatcga tatccgtcat
     8821 gaaaaggact tgctggctga cccgttcctg catttccatt gctactttag gaactgaaac
     8881 accatattct agataacagt aaagatctac tttcaagcca tcttcctcgt ttgctaagta
     8941 aacacctttt ccgtgagctg cacgtcctaa taattcagtg acattgctgg caaaagttcc
     9001 gcgcattccg tatacgcctt ctactttaga agctgcaatc ccgataatta cttcgatgac
     9061 ttcaggagcg atcacgatct ctcctaaatc ttggtttgcg tttaaaatca aatttttttc
     9121 atctgccatt tatttattcc tccctttgcc taagcacgag atacatccga attctctatg
     9181 atgcggcata gtgatcacgt ggtaagaaaa ctgccgccga tcagctgcaa actgctatga
     9241 attggagaaa acacccaact ttattatctc ttacagctta aaagttcttc tatagtgtat
     9301 cattaaatcg agtgattttc tataacaaag tctgtgaaca ctgattttta cgcttacttc
     9361 ttctattgat gaaactataa gatgatcaat tcttttggtg aacgagtcaa cacacgattt
     9421 ccatcttctg tgatcaacaa gtcatcctca atacgtactc caccgattcc tggtaagtag
     9481 atccctggtt catcagtgat cacatttcct ggtacaaatt gcttttctgc acgagaagaa
     9541 acgtttggtc cttcgtggat ctctaaaccg atcccatgtc ctgtagaatg tccaaatgct
     9601 tccccgtaac catgttttga aatataatct ctagcaactg catctaattg gacaccagtc
     9661 attcctggtt ttgcagcatc aataactgct aattgagcat ctaagactat ttgataaatt
     9721 tcttttaatt tttccccagg atcaccaata gcgaatgtac gtgtcatatc ggaaacgtac
     9781 ccttcgtaat agcaaccaaa gtccaatgtg atcaagtcac cttgttcgat gatttttttg
     9841 cttgctacac catgcggcat agccgaacgc aatccgctag caacgatcgt atcaaaagaa
     9901 acacctgaag cgccaagaga acgcatataa aagtctagtt gatttgcgac ttcaatctca
     9961 gtcatgcccg gttggatcat tttcaggatg tgatcatatg ccatatccgc aatatgacat
    10021 gctttttcga taatagcgat ttcttcttca tctttcactt ctctgagttc ttcgatcatc
    10081 tgtgaaacag gtactaattc cgcatcgatg atttcttcta aaaccgaata ttctaaaaat
    10141 gagactgttg tttcctcaaa agctaatgag tgcagttctt ctttgcgtac taagtttgct
    10201 acctcatcaa aaataggtcc gacattttta ataatttcaa acccttgagc ctgcgctgcc
    10261 gcctgctcgg tataacgaaa atcagtaata aaaaatgctt tttccaaagt aataacagct
    10321 aatcctgtcg tacctgtaaa gttcgttaag taacgaagat tgtacggact ggtaaccaaa
    10381 aatgaatcca aattttcttc ttgcattttt ttgcgcaatt tttctacacg tagcatcata
    10441 atgaaactcc ctctttcttt gcacgctttt ttccattata gcaaactttt cttcgtacac
    10501 gacagttaaa taaaaatttc cggaaaactt ctttttattt taaataaata aagccaaaaa
    10561 ggagtcacag tctcgctgca actcctttta gtttactatt ttgtaaaaac ttatgatcgt
    10621 tttccaaaga aaaatgagac aactgctacc aaaatcactg cgcctaaaat agatggaata
    10681 agtgccatac ctgcagcttt tggtccccat tcgccgaaaa tcgcttgtcc aatacttgaa
    10741 ccgactagtc cagcaatgat attcgttaca cagcccatcg aatttccttt actggtgatc
    10801 gcacctgcaa ttgctccgat cacggctcca acaatcaatg tccataacca actcataata
    10861 taacctcctt ctttgctaat caattttagc atatgggatt taaaggggac aaataattgg
    10921 ttttgctatt tcatattttc ttctgcaaag taaaaaaata aagaaaacct cctcttagaa
    10981 gttttcttta ttttttactt gcgtttaaac atactacgaa taccacgttt cactacatca
    11041 aagaaactca atgattgtac cattctatct tcatctacat attctctgat cgcacgaagc
    11101 acttttttag gttctttgga agaaaatgtg tatgtaccat tttttttcgt ttgaatggca
    11161 tatcgaggaa tccattttcc ctttagcatg actgatgcta gtacataatc cacttcttcc
    11221 catggaattt ggatatattt gcgtctatct cgcgcatggt aaaactcaaa accattatta
    11281 cctatcatga tttgcccgta atctgtcaga cccgtaaacg aagtagcatc aattaccaag
    11341 tctacttttg tattgattga ttgaaccatt ttctccctcc agatatttgt ttatgaacag
    11401 tatactatat aaaaaaagct cgggacaacg cccgagctat atttttatgg attataaaag
    11461 tccgatgacg tgtccaacaa caccgactac gaataaacca aggatgataa cgattggaga
    11521 aacctttttc ttaagcaacc acatacataa caatgttaat cctaatgcag ctaaaccagg
    11581 aatcaattgg tctaagttgt cttgtaatgt tgttaccttt tcaggagaaa gggctaagcc
    11641 attattaact tgttcaaatg cactcttgat tccttcacca cctgaaggca atttatccca
    11701 ttcgatgtaa gcacctttat ctaattttac agttgataca actggtaaga atttgattga
    11761 tacccatctt tgtacaaggg cagctaatac gaacatccct aaaattgaag caccttttgt
    11821 tacgtcttgt aacaatccgc cagaaaggtc atcagtaatt ttagaaccag ctttgtagcc
    11881 aaattcttgt gtataccaca tgaatgccca acgaataatg ttccaaccta agaagaagat
    11941 gattggtcca aggatatttc ctcccatagc taatgaagca cctagtgcac ctagcattgg
    12001 acgtactgta aaccagaaca ctgggtcacc aacaccagct aaaggaccca tcatacctac
    12061 tttaacccct tgaatcgcta catcatcaac aggcgcgcca ttcgcacgtt cttcttccag
    12121 agccaatgta acccctaaaa ttggagaagc aatgtatggg tgtgtattaa agaattccaa
    12181 gtgacgtttt aatgctgcag aacgttcttc ttttgttttg tataattttt tgattgctgg
    12241 aatcatagaa aatgcccagc caccgttttg catacgttcg tagttccatg aaccttgaat
    12301 gaaggtagag cgccacgcaa cagctaaacg atcttttttt gataatttga ttttttcttc
    12361 tgccatttta ttttcctcct tcaagattaa tagtcattca aaatgtcgcc taaagggtca
    12421 ccagagttgc ttccgcctcc attatttgat gaaccaccca ttttagaaag gttcaagtaa
    12481 ataagagcta atgcaacacc taaagcacct agagcaatca atgttaattg agaaattgca
    12541 gctacaacga aaccaataac gaagaatggc catacttctt ttgtagccat catgttgatt
    12601 accaaagcgt aacctacagc tacgaccatt cccccaccga tagccatacc atctgttaac
    12661 catgctggca ttgattcaag gaatgattgc acagtttgtg ctgggataaa tagcaacgct
    12721 gctgctggga ccgcgatacg aaccccttgt aaacatacag caatgatgtg ccacatttca
    12781 accttacgga tgtttccttc ttcagcagcc gcatccatca aatgaacgat tggaacagcg
    12841 attgtacgta cgatcattgt taagaacaac cctgcaacag ccaaaggaac ggcaatcgcg
    12901 atcgcagaag gaacaccttt aacaccttgt ccacctaaaa ctaaaataat tgctgatgct
    12961 actgatgcta atgcagcatc tggtgctaca gcggcaccga tatttgccca acctaaagcg
    13021 atcatctgaa gcgtaccgcc aagtacgata ccagcttcga ggttaccggt aactaaaccg
    13081 atcaatgtac atgccactag tggttgatga aattgaaatt catcaagaat accttccata
    13141 ccagctagaa aggcaactaa tacgactaaa attattgaaa taatagacat gataagcctc
    13201 ctataaattt taatattatt tattacgctt ttgctaattc agcttttgct tttttcaaaa
    13261 tatcatccat gttatcgcgt gaatcattag gtactttacg tacatcgaat ttcacacctt
    13321 tttgttcaag cttctcaaac gcttcaacgt cttcttgtcc catagacaat actttactta
    13381 caacgacttt accgaccgaa tgcgccattg acccaacatt taattctttg atgtctacgc
    13441 caccttcaac agctgtcaat acgtcttcag gattttcaaa taaaagcaat gctttggtat
    13501 ttccaaaacg agggtctttt gctacttcga tcattttgct aataggaata acatttgctt
    13561 ttacacctgg aggagcagct tgttcgatta gtctcttacg cagatcatcc tttgatactg
    13621 catctgaaac aacgataata cggtttggtt gcactgcttt tgtccaagct gtcgcaactt
    13681 gtccatgtaa cagacgtgag tcaacacgtg ctaatacata tttgattttt ccgtctccga
    13741 ccacagttcc ttctggaagt gctcctttag gttgtgcgtc ttcaactgct gctttcggtg
    13801 cttctgccgg ttctaattct tccggtttta cttttacacc gtcttttgct gtttcaatga
    13861 tgtgtgctgc aatttcatga gcagattcca ttgaaaagcg tgatgcgtag gcttcaatca
    13921 acattggtaa attcaaaccg ctgacgattg cccatttatc tttgtgctct tcgaataatg
    13981 tgtttgattg attgaacggt gttccgcccc ataaatcaac taagaataac acttcgtctt
    14041 gattatcaaa agaagcaacc gcttcttcca atttggctct caagtcatct ggaccttcac
    14101 ttggtttcaa aatcacggct ttgacgtttt cttgttcgcc aaagatcatt gaaccggatt
    14161 gtaagattcc ttcagcaaat tgtccatgac ttgctaggat aatccctacc atatttatac
    14221 ctcctattta cttttgttgt aacaaattca aaaatattaa taattgctaa ccattacaac
    14281 agaattattt gaccttttcc aacaaccatt cttgctacac ctttttgatt ttcgctagta
    14341 gttccatcaa aaggattttc ctgtcagcag gtacttttcg aatctctaac tccacttctt
    14401 gactgttcaa gtaacgaaag gaatcaatat cttgttgatt tactgaaaca aaattggtaa
    14461 tcattgattt gccttcagta aaactcatac cgccgatatt caacgacttc aactgtacac
    14521 cgcagcggac aaccgcttca acatcttggg gattggtgaa taaaagcatc acttttgctc
    14581 gtgataataa tccactatga tagatttgaa tcattttctg cacggttatt acatttgctg
    14641 tgatccccgg cggtgcagct tcttttagta gaaactttct caatttatct tgagcgacta
    14701 catcgctgat cacaatgata cgttcaacac ctgtttgctt cgaccaaact gttgcgactt
    14761 gcccgtggat taaacgatca tctatacgtg ccaatcgaat atccatctgc aaaactcctt
    14821 cttcctcact acttcacaga aacccctatc atttctgtgt gaacaaccac ctcctagcac
    14881 acactactat aagcaaaaag cgtgccaact tttttacgat acactaattg aatttaaagg
    14941 attcttaacc aatacacaaa aacgatacac tataaaagtg tatcgttttt gtgtattcat
    15001 ggcacagtgt attctttttt atctaactga ttatggacta gacgtagcag ataatacatt
    15061 tcttctatcg gcacttttac ttttatctga tcttccaaca gaacaactga ggctgccaat
    15121 tggctataaa gaggatcatt cgttgtattt gtcaattcgt tttcttccac agtcaatggt
    15181 tcattccgaa taatacgttc gatcattcct gctgtgtgca tcactaggtt gattttgaat
    15241 ccatattctt catcgccgat tcccgtcgtc tgagagattt gtgtagaaaa ttgccacatt
    15301 ggatcgatta acttactacc attaataaag atgaagttat cagagataaa ctcaacacac
    15361 gtatttttag ctgactcttc atctagggag atgaattcag tttcctccaa ttctgattcc
    15421 atcagcaact gatccaaaat gacttcgata ttttgatcaa taaaacgttc taaaggaata
    15481 aatggggctt ggatattcaa atcagtaatc ccagtagtag ctatgatctg atattctttt
    15541 tggataactg gcagttcttc tttcacttcc acaatcgaca aagctagaac ttctaattct
    15601 gtttcttgac gcttgtttac cgctcgttcg atcaattctt tgattctttg tgctgtacct
    15661 tcgccagatg cgcagatagc caaaacagct tttttcttat gaataggttt tgcttcctga
    15721 acagattcta cagaagatat ttctgcgtaa cctcgaaaat ttttcaatga ttcatgcaac
    15781 atatctagat ctgtccctaa tactgagacc tttcgtacag tttccaaaac tagagaagtt
    15841 gttaccatat caacagtacg tactggaatt ccagtgtctc tttgaatttg cgaattaaac
    15901 gacgcaaggg accccatatc tactaagagt atgaccccgc ttccttcatc tacttcttgt
    15961 acattgcgtt caattcggtc caatgctgtt ttcggatcca tatccaaagg catgtctact
    16021 gctcgtacgt tctctgcatc taacaactgt tggacaactt ggaccatact gcttgctgtg
    16081 ctgtttccgt gagctgcaac gactacaccg attctgccgc ttgcttgatt tgcccgtaac
    16141 gagacgagta gaacggtcaa gtaatagtct tcactttctg gaatctccac ttgaaaatac
    16201 gtttcgatat aactacgcac ttctttcgca acagcatatt catctggaaa atcaaaagcc
    16261 atctcacgga tgttatcatt cgtatgccgt tcttctccta agttgatttt tttcaaaaaa
    16321 gaactgatat gcaagctcat agcataaata aagttttgct gaaactcata tggtaaagat
    16381 cttttgacca ttacataaat ctgattggtc acttctatga ttttcggatc tacaaattct
    16441 gctaatttgc tgtctgcatt aaaagaaaaa ccatggtctt tatagaaaga cttcagatgg
    16501 atgttgatat ctgtagaaat gaaatgattg attgcttctt gatccaaacc atccgacttc
    16561 agtaaagctg ctttatctcc gatgatatca tatagattat aaggtaactc ataggagtcc
    16621 gattggattt tcatgatcgt atcatttggt gctacagtta tctttggctc caatatttta
    16681 gaaagctctg ccattgcact gcggttgctt gctaattgaa tcaatccgct acgaatccct
    16741 tctgtcaaat catcgattgt gatcgagatt tcgggtgatt gcatatgatt tagaaatcct
    16801 cgtgcacata ctaactggat atttgacttc aattgtccta tatttccata ggtcacactg
    16861 ccgatcaatg cttttgctac atcttctgtc aaagaaatct ttcgctgcgt gcggtttgct
    16921 tcgtgggcaa tcatgatttt tactaaatcg actttctcat ttgcaggacg tttttcaaaa
    16981 gccggaagtt tgatattgat tgggatacgc cgaacaaaag tttctaatag agaagaacct
    17041 gggtcttctg tggtcgcacc tacgatccgt acatttgctt catgggattt cgttgtttcc
    17101 ccaagacgac tgtaagttcc atgatccata aagtaaaaga tcatttcttg accttcaggc
    17161 ggcaaccggt gaatctcatc caaaaacagc ataccgccat ccgcttgatc gataatcccc
    17221 attttttctt catctgcgcc tgtaaaagca ccttttgcgt acccaaataa atgactcatc
    17281 aaaagctcag ggttattggc ataatcagca caattgaaaa caatcagttc cgtttcctca
    17341 tctattacat gatgcgcttt tgcaaaatga tacatcgcgt gtgcaaaata agtctttcct
    17401 gatccggtag gtcctgtaat caaacaattt aatcctcttg gcggatacaa aatcgcagct
    17461 tttgcctgtt ccactgaatt tttcatgctg ccgttagctc caatgatttt tgcaaagata
    17521 tccttagtat ctatttggag tgtatttttt tcttcagaga ccggcgtttc tttgtaactg
    17581 actacatgtt ttgtaactgg ctttacgtgc gtaacgagtg tttgatatat gtaacgtact
    17641 ggtcgtccgt ctgtctttat cagttttcct tcgcgcacta gctgattcag atctttactg
    17701 ctatttgttc gctgaatccc taacacttca gcaatttcct gtgttgttac tccttgatca
    17761 tattctgcct ttgttaaatg agcggttttt tctttgacat acatataaat tcggtcaatg
    17821 cgttttgcca atggtatcgc tccttttcta tagactattg tacttaggct tcaaaacata
    17881 atactatgta tttatttctg tttcgtcaac tatttacctg attttgtttt gttgataaca
    17941 cgcggataga tagaaatgtt caatttaaaa gaacgaaaaa tcccgatacg atttttataa
    18001 tggaaacaag aaaaagaaca ctgtttacca tataattatt tcactgatag caaacaatat
    18061 agcttccatc aattgaaaac gatagttatc aaaacatcct gattccaaat tggcaaaaaa
    18121 atattaagtg taaaaagaca aagtaaactt cgtagcctcc actacaactt ttatttttat
    18181 aaacaaaaaa ggctgtgaca aaagtcttgt cacaacctct ttaatcataa gattcaatta
    18241 agcttcttga gctactggat aaacagacac ttgttttttg ttacggcctt tacgttcgaa
    18301 acgtactacg ccatcaactt ttgcaaataa agtgtcgtct ccaccgatac ccacgtttac
    18361 acctggatag atttttgtac cgcgttgacg gtaaagaatt gatccacctg taactgtttg
    18421 tccatcagca cgtttagcac ctagacgttt tgattctgag tcacggccgt tagatgtaga
    18481 accgccacct tttttgtggg caaataattg tagattcata gataacaaca tggtctgcac
    18541 ctcctattta tcattaattg ttttaatttg gatatattct gagttttcag cttctatcga
    18601 ttgtaatcct aataaaagat tttctaatag aatctcagca atattgtttt gttcttgtgt
    18661 cattcctgaa gtgacttcgg tataaagata accgccttct tcttcattca tttcaacaat
    18721 cggctcaaaa ccggctaatg aggcaatccc gttgacagtg ctgatcgcta acgcagaaac
    18781 acccgcacaa acgatatcac ttccataagg accagcatca gcatgcccgg tcaaagtgaa
    18841 tgaaacgatc tgacctgcgt catttcgctt aaatgttcct ttgatcatat ataggccttc
    18901 tttctcaaac gctattaagc gttgatcgcg tcgataacca cttttgtata tggttgacga
    18961 tgaccttgtt tacggtgtga atgtttttta ggtttgtatt tgaaagtaac gactttcttt
    19021 tgtttgccgt gtttttcaac agtaccttca acagttgcac ctgcaacagt tggagcgcct
    19081 acttttgtag attctccgcc tactaagata acttcgtcaa aaacaacttt ttctcctgct
    19141 tcaacgtcaa gtttttcaac atagattgct tgtcccactt caacttttac ttgtttacca
    19201 ccagttttaa taattgcgta catgctataa agcacctcct tctgatatac ttagactcgc
    19261 catccgaagt gacagcatat gctgtgctta ttacttgttc tgagcggttg tagctgtgga
    19321 gtccacaatt acaacagtac tagcttacca gaacagcaac cgttagtcaa ctaaatttaa
    19381 aatcaaaaag taaaacaaaa attcaagcaa tacttctgct tttctatcct cacagttcta
    19441 ccaaataaaa tagtcgcatt gtgtttcttt tattcttata ataaaagaaa aaggaggagc
    19501 ataaatggaa tacccaaaag aactgataca agaagcttct ttaagaatga acggccgtcc
    19561 tgtagaagga tttatcgctg ggcaaggacc tcttcatcct aaactgatgc tcgtgggaga
    19621 agccccaggg aaaacagaga ttgatacgca tgttcctttt agcggtcaag ctggaaaaga
    19681 attgatgcag gcactttctt caactggctt aacacgagaa gaggtgtata tcaccagtgc
    19741 tgtaaggagc cgcccgtatc gcgtgactca tcggatcaat aaacggacac aacagtcaga
    19801 aactgtttat ccaaatcgga cacctactcg ttccgaagta tttgcgcatg caccaatatt
    19861 ggattacgaa ctgatgaagg tccagccaaa attaattgcg acacttggaa acattggtct
    19921 tcaacgttta cttggcaaag aatatacggt taccaaaaat catggtcaac tctatacagg
    19981 gcctgtctta caattaacag aacaaaagga tgcctacgaa tggtcagaaa aaaactatcg
    20041 aattcttcca ctttttcatc cagcagctat tttctacaat cgctcccttg tacctgttat
    20101 ccatcaagac tggcaagtac tagcttcact tttacagcaa tattaaaaag aacagacaag
    20161 accataaaat cttcagttta cagtcttgtc tgttcttttt cattgtttta atggctaatt
    20221 gcagtatatt tcgcatgtaa agctgtcaac gcatgagcaa ctgtttgatg ttgatgcgtg
    20281 aatgtatgtt cccacaagtg agaaagttgt ttttctactt ctggctgcaa ggaagtatag
    20341 ataatcgttt gtcctctttg ctctgctttt tcttgaaatt catcaaaaac tgcacgtgcc
    20401 gtcaaatcaa tacttggtac gcctcgcatg gagaaaatga caccatcgtg atgatttagt
    20461 tcttccaatt tatttttgag tttttctgaa gacataaaaa acagtggacc actaatatac
    20521 actactgtcc agttattcag cttttccgtt tctggcagcc ccattctttg ccaatcgatc
    20581 gtttctaatg aaatcgtgat agcagcgctt ttgacaacaa aaaatacaca gccgccgatc
    20641 accccgatca cgatagcaat acttaaatca aagataactg tacaaatcat cgtaaggata
    20701 aacaatagaa ctgctgacca atatttatta gtaaatagct ccttgatcgt ttcccattca
    20761 ttcatacgcc aagccgtcac aatcaaaaca cctgcaagtg ctggcattgg aatctgtgac
    20821 atcactggcg caaaaacaag catggagagc agtaagacaa ctgcatgtat cataccagct
    20881 aatctagttt gtgcaccaga tttgatggcc acgcttgtac gggcgatggc cgcagtagca
    20941 ggaatcccgc caaagaaagg aagcaacaga tttccaattc cttgcgccat taattcttga
    21001 ttgctatcta agggcttatt tgccattcgg ccagccgaag caccacatag caagctttca
    21061 atcattccta ataaagcaat gctaatagct ggaactgcca cttgttgcaa ggcagaaaag
    21121 ctaaaatctc ccatattcaa acgattacta ctgatcaatg tttgtggaat cttacccaca
    21181 gttgctactg gtaaatggaa caatagcata actgctgttg ccaaaatgat agccagcagc
    21241 gaactaggca ttcgtttcgc ccattttttt ggatagataa acatccctaa aatgactagc
    21301 cctcccatga tcaaagaggc tgtgtttatc ggaaatccta tcgtttgata actacttagt
    21361 ttttcaataa cgtttgtacc ttccgagtga acaccaaata aattatcgat ctgacctaat
    21421 gcaataatga tagcaatacc tgaagtaaac cccgtaatta cgggtgctgg gataaaagaa
    21481 gtcagtgttc ctaatcggaa aagtcctgct gcaagtaaaa atagacccgc taaaaaagta
    21541 gcaagcaata caccttgcat tccctttgtt gccgcaatag acatcaagat agctgccatc
    21601 gcacctgtcg gacctgatat ttgataaaaa ccgcctgata aaccgccaat aacgataccg
    21661 gcaatgatag ccgtaatcaa acctgcggcc gcatcagctc cgcttgatac cccaaaagcc
    21721 aaggctaaag gcaatgctac agcagctact gtgatcccag ccaaaagatc tttctgaaat
    21781 cttgaaagat cataacctga aaattctttt tttagtgagg aaacataatt tttgaacacc
    21841 tatctaactc ctttttcatg aaattttcta aaataccatt cattagaata tcatatttca
    21901 tgagataaag taatattttt cacaaagttt cctgttagat aaattcttat tttttctata
    21961 tttataagaa aatagaaagc aatgccaaca gagctagccc accttgtttg agtaaaatcc
    22021 aacgatcgct agtcaaactg cca
//
LOCUS       DAMEEU010000052        20391 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.053, whole genome shotgun sequence.
ACCESSION   DAMEEU010000052 DAMEEU010000000
VERSION     DAMEEU010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20391
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.053"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            134..409
                     /locus_tag="PB779_001903"
     CDS             134..409
                     /locus_tag="PB779_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HDE0739424.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            415..1182
                     /locus_tag="PB779_001904"
     CDS             415..1182
                     /locus_tag="PB779_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HDE0739425.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            1350..3179
                     /gene="typA"
                     /locus_tag="PB779_001905"
     CDS             1350..3179
                     /gene="typA"
                     /locus_tag="PB779_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HDE0739426.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            3440..5212
                     /gene="recQ"
                     /locus_tag="PB779_001906"
     CDS             3440..5212
                     /gene="recQ"
                     /locus_tag="PB779_001906"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HDE0739427.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGINKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            5326..5628
                     /locus_tag="PB779_001907"
     CDS             5326..5628
                     /locus_tag="PB779_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HDE0739428.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            5631..6794
                     /locus_tag="PB779_001908"
     CDS             5631..6794
                     /locus_tag="PB779_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDE0739429.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            6820..10248
                     /locus_tag="PB779_001909"
     CDS             6820..10248
                     /locus_tag="PB779_001909"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HDE0739430.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKNGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            10269..11393
                     /locus_tag="PB779_001910"
     CDS             10269..11393
                     /locus_tag="PB779_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739431.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            11383..11820
                     /locus_tag="PB779_001911"
     CDS             11383..11820
                     /locus_tag="PB779_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HDE0739432.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            11804..12142
                     /locus_tag="PB779_001912"
     CDS             11804..12142
                     /locus_tag="PB779_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HDE0739433.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            12261..12821
                     /gene="rsmD"
                     /locus_tag="PB779_001913"
     CDS             12261..12821
                     /gene="rsmD"
                     /locus_tag="PB779_001913"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HDE0739434.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            12818..13309
                     /gene="coaD"
                     /locus_tag="PB779_001914"
     CDS             12818..13309
                     /gene="coaD"
                     /locus_tag="PB779_001914"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HDE0739435.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            13299..14342
                     /locus_tag="PB779_001915"
     CDS             13299..14342
                     /locus_tag="PB779_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HDE0739436.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            14501..15229
                     /locus_tag="PB779_001916"
     CDS             14501..15229
                     /locus_tag="PB779_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HDE0739437.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            15345..15590
                     /locus_tag="PB779_001917"
     CDS             15345..15590
                     /locus_tag="PB779_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HDE0739438.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            15587..15805
                     /locus_tag="PB779_001918"
     CDS             15587..15805
                     /locus_tag="PB779_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HDE0739439.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            15941..16480
                     /locus_tag="PB779_001919"
     CDS             15941..16480
                     /locus_tag="PB779_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HDE0739440.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            16473..18746
                     /locus_tag="PB779_001920"
     CDS             16473..18746
                     /locus_tag="PB779_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HDE0739441.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            18784..19830
                     /gene="holA"
                     /locus_tag="PB779_001921"
     CDS             18784..19830
                     /gene="holA"
                     /locus_tag="PB779_001921"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HDE0739442.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(19919..20173)
                     /locus_tag="PB779_001922"
     CDS             complement(19919..20173)
                     /locus_tag="PB779_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HDE0739443.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
BASE COUNT         6839 a         3429 c         4354 g         5769 t
ORIGIN      
        1 aaaaatcagt tgcgttttgt tttttagaat tatcaataat attattatgt aaacttaaaa
       61 atatgacaac ttcttggttt attaccactt cctatgctac actgaagagg aatatgaaat
      121 aggagagttg aagatgcaag aatatcagta tccacttgat ttagattgga caacagacga
      181 aatggtcatt gtaatgaaga tgtgggaaga tctggaacgt gcgaatgaaa aagggataaa
      241 caatgaagct tttttgaaga cttatcagca gtttaaaact gttgtcaaat ccattggtga
      301 ggaaaaacga ttgggacggg aatttgaaaa agcttccggt tattctttat atcgtacagt
      361 gcagcaagca aaaaaaaatc caaacaaaac tttgagaatg aacgggtgag ataaatggaa
      421 cagatgattg atcatatcaa gtcctggctt gaagaagctg gtgagaaaat caaatcttct
      481 caacaaacat taacaatctc gcaaaaatca aatcgaacgg atctagtaac aaatgtcgat
      541 cgaaacatcc agaattttct aatcgaaaaa atccattcct ttgatccaga ggcgaaaata
      601 ttggcagaag aagaagggtg taatcaatta tcggatctcg atggaagagt ctttatcatc
      661 gatcctattg atggcacctt gaattttgtg attgaagggg aaaatttttg tattatgctc
      721 gctgtttatg aatccggcgt tggaaagctt ggtttcattt atgacgtgat gagaaatgaa
      781 cttttttggg gtggaaaagg aataggcgtg tataaaaatg atgagccatt gcctagacca
      841 gcaaataaat ccttatcgga aggcttactt ggtgtgaata gttatctttt cggtcataat
      901 aaatatggaa tccgagaaat tgcggaaagc agcatgggga cacgtatgta cggatgcgct
      961 ggtcttgaac tagtggcaat cttgaaagga aaccacattg cttatatttc aaaccttagc
     1021 ccttgggatt atgcagcggg aaatgtctta ttggaagagt ttggtatggt aacaagcggt
     1081 ctttttggta ctcctttgac atttgaaaaa agggaatact atttagcagg gacttcttgt
     1141 gcatatgcag aaatcgcaga ccttttgaaa aaagaaggct gaaaaaaagg tagaaatcat
     1201 tcacaaaaat gataaaaacg agcaaaagat taattttctc gaaaaaatga aaacatttta
     1261 ctatatttca tgaaaaaagt ctgctataat tagcagtcga gtaaaatttg ccctgtcata
     1321 aagaaccaat aaaaaaggag ttagttacat tgaattatag aaacgatatc cgtaacgtcg
     1381 caattattgc ccacgttgac cacggaaaaa caacattagt tgatgaacta ttaaaacaat
     1441 cagatacatt agacgcacat acgcaattgc aagaacgtgc gatggactca aatgcgctag
     1501 aaaaagaacg tggtatcacg attttagcca aaaacacagc tgtagactat aaaggtattc
     1561 gcgtaaacat catggatact ccaggacacg cggacttcgg tggcgaagta gaacggatca
     1621 tgaaaatggt tgacggcgtt gtgttggtcg tagatgcgta tgaaggaaca atgcctcaaa
     1681 cacgttttgt attgaaaaaa gcactggaac aacatatcac accaatcgtt gtcgtaaaca
     1741 agattgacaa accttctgct cgtcctgagc atgtcgtaga tgaagttctt gaactattca
     1801 tcgaattagg agcagatgat gatcagttag actttcctgt gatttatgca tctgcactaa
     1861 atggtacgtc aagcttgtca gatgatccag cagatcaaga accaaccatg gcacctattt
     1921 ttgatacaat tattgaaaaa atccctgctc ctgtcgataa cagcgacgaa ccattacaat
     1981 tccaagtttc attacttgac tacaacgatt atgtaggtcg tatcggaatc ggacgtgtat
     2041 ttagaggaac aatcaaagta ggagaccaag tagcattaat taaattagac ggaacagtta
     2101 agaaattccg tgtaacgaaa ttatttggtt tctttggact aaaacgtcta gagattcaag
     2161 aagcaaaagc tggagacttg attgctgtct caggtatgga agatatcttt gtcggtgaaa
     2221 cagttactcc tgtggatcat caagatgcgt tacctatcct tcacattgac gaaccaacat
     2281 tgcaaatgac tttcttagtt aataattcac catttgccgg tcgagaaggt aaattcgtaa
     2341 ccgctcgtaa gattgaagaa cgtttgatgg cagaacttca aacagatgta tccttacgag
     2401 ttgaaccaac aaactctcca gatgcatgga cagtttctgg tcgtggagaa ttgcatttgt
     2461 ctatcttgat tgaaaacatg cgccgtgagg gatacgaatt gcaagtatct cgtccagaag
     2521 ttattgaaaa agaaatcgac ggtgtaaaat gcgaaccgtt tgaacgcgtg caaatcgata
     2581 caccagaaga atatatgggt agtgttatcg agtccttgag cttacgtaaa ggtgaaatgc
     2641 aagatatggt ccatacagga aacggacaaa tccgtttgac attcttaaca cctgcccgcg
     2701 gtttgattgg ttattcaact gaattccttt caatgacacg tggttacgga atcatgaacc
     2761 atacttttga ccaatatctg ccaatgcttc ctggtcaaat tggcggacgt caccaagggg
     2821 cgcttgtttc gatcgataca ggaaaagcaa cgacttattc tatcatgagt atcgaagaac
     2881 gcggtacagt cttcgtagaa ccaggtacag aagtatatga aggaatgatt atcggggaaa
     2941 acagccgtga taatgatttg actgtcaaca tcacgaaagc aaaacaaatg acaaacgtac
     3001 ggtctgctac taaagaccaa acatctgtca tcaaaaaacc aaaacaattg acgttggaag
     3061 aatctttgga attcttgaat gatgatgaat attgcgaagt aacaccagaa agcattcgct
     3121 tgagaaaaca aattttagag aaaaatgctc gtgaaaaagc atctaaaaag aaaaaataat
     3181 ctgtaaaagg atgaagagag aaaccagctt gttataaaaa atagctggtt tctttttttg
     3241 tccaactctt ttctgtggag aagtcatctt tgtcaatgga cataaattca gaaaatacgc
     3301 cgaaagacgt ttaaaagact tttaaaaaac ttatttctag agagtttttg tttcataata
     3361 agataatgtt tcacgaaagg agatcaactt gtccttcgaa gaaaatcgaa gtaaaatggc
     3421 aagagaaagg agcgggaaga tgaacgactt attaaaacaa tactttggct atgatgagtt
     3481 tagacctggt caaaaagaaa ttatccagaa agtcattgat caggaaaatg tattaggaat
     3541 catgcctacc ggaagtggga aatcaatctg ttaccagctt ccagctttac tattagatgg
     3601 gcttactgtg gttgtgtccc ctttaatctc tttgatgaag gatcaggtgg acgcggcgaa
     3661 tcaattaggt atacccgcca cttttatcaa tagctcgtta gatggttacg aaacagctag
     3721 acgcttccaa gaaatcgata gacagcagta ccgtttactt tatatcgctc ctgaacgttt
     3781 tatcatgccg gattttatcc aagcaatgaa gcgatggaac gtccgtatga tcgctattga
     3841 cgaggcacat tgtatctctc agtgggggca tgatttccgc ccaagttatt tacagatggc
     3901 gaaccagcta gatcaactgc caaatcgtcc tgtaattgtt gctttgacag ctacagcgac
     3961 tgtgcaagta gctgctgaca taaaaagact tttaaaaatt ccagaaaaca accatattca
     4021 gactggtttt gaacgagaaa atctacgatt tcaagtaatt aaagatcaaa aaaaagaaca
     4081 atatctaatc gaatatttaa agatcaacaa aaatcaatct ggtatcattt atgcagcaac
     4141 gagaaaagaa gtagaccgtc tctatcattt gcttaaaaaa ttcgattttt ccgtgggtag
     4201 atatcatggt ggtctaaatg agaatgagcg aacagaaatg caagaagcct ttttatacga
     4261 tcgcttgcag ctgattgtag cgacaaatgc atttggtatg ggtataaata aaagcaatgt
     4321 ccgttttgtt atccattatc aaattcctgg ctctctagaa gcatactatc aggaagctgg
     4381 tcgggcggga agagatggtc tttccagtga agccatcctg cttttctctc ctcaagatat
     4441 ccaagtccaa aagtttttta tccagcagtc ccaaagagaa gaagggcaaa agcaaaaaga
     4501 atatgaaaaa ttaaaagcga tgacagaata cgtgtatatt gagtcctgtc ttcagcaata
     4561 catcctaaac tattttggcg agacaagcag tccgtgcaac cgttgtggta actgtttaga
     4621 tgacagagaa atagtagaag taacgacaga agcacagatg gttctttctt gcttaaaacg
     4681 tatgggtgag aactatggta aacaaatgct gatgaaagtc ttagcaggat cgaaagaaca
     4741 aaagctgcaa gctttaggtt ttggacattt atctacctat ggactgatga aaaaccaatc
     4801 gcaaaaagaa acgatgcagt taattgaata tttgatatcg aatggctatc ttctgaccat
     4861 caatggtgag tatcctgttt tgaaagtaac agaaagaggg atacaagtat tgaaaggaca
     4921 agaatctgtt tatcgaaagg aacccaagaa agtccagcag ctatcggatg aagaaaccga
     4981 tacactattt gaagtgctgc gggaactgcg aacggatcta gcatcagaag caggcgttcc
     5041 cccgtatgtc gtattttcag attccacatt gaaagaaatg agccgaatac gtccatcaag
     5101 cagattggag atgcttcaga taaaaggagt tggccaaagc aagcttgata aatatggcga
     5161 agccttttta tctcggataa aaaatgcgga ctctaacgtt ctggataagt agaaagaacg
     5221 aatacgtaaa aatgaataaa aacaactggt taaatctgtt ttttttgctc cttatgaaaa
     5281 tcaaatatgt tataattaag gaattagaat gggaggtaag cacagatgga ttctttgtcg
     5341 aaaaaacttg cgatccaagt attaaatgat gaagcagaac ggatcaaacg attaatccga
     5401 aatcaaaaca acagtctctg tatctcacaa tgcaaagcct tcgaagaagt ggtagataca
     5461 cagatgtacg gcttttcccg gcaagtcggt tttgctgtcc gtataggagt aatcggaaag
     5521 aacgagggcc agctgatgtt aagtgagcta gaacgagaat tgaatcagtt atatagtgag
     5581 gtttaccaag aaatttatga taaaaaagaa gttggcaagg aggaatagac ttgcctaaga
     5641 aagtgaaaaa aaggcatcta ttagactata gcatcttgat tccctattta attttatgtg
     5701 tattgggatt gatcatggta tatagttcta cgtcgtatct attattagaa aacggacaaa
     5761 atccgtccgc atcagtcatt aaccagagta ttttttgggt gcttagcttg attgctatcg
     5821 cactacttta taaaatgaaa acagatgttt tgaaaaacca gcgtttgatc atggcagcca
     5881 tcgcagtttt gacgattttg ctgctgattg ttgtgttttt tggtaaggag atcaatgggg
     5941 cgaaaggttg gctgcaaatt gcaggattct cgatccaacc tgccgaatac ctaaaaatca
     6001 tttctatctg gtacctgtct ctgactttat ctaaaagaca aaacagtgta caaaaagatt
     6061 ttcttgggac tgtgaaacgt ccacttgcaa tggttatcgg acttactgca ttagtcgcta
     6121 ttcttcccga ttttggtaat gcggcagtta tctttttgat tattttggtt ctgcttttag
     6181 ccagcggagt caattatgtg tatactttga ttgtaggagt aggaggcttt tgtctaagta
     6241 cttttacgat ctggctgatc aatatcacaa acggaaagat cttacccgga cgtttacagt
     6301 atatctataa tcgatttgct atttaccaaa atcctttctc agacgaatta aataaagggc
     6361 atcaactagt caacggctac tatgccatgt tcaacggagg actatttggc aggggattag
     6421 gtaacagtat ccagaaaaaa ggatttttac aagaagcaca aaccgatttt atttatgcaa
     6481 tcgtagtgga agaactggga gtgattatgg ggattttgat attagcgttg ctattcttta
     6541 tgattgtgcg cattgtcctt gtaggtatcc gttcaaaaga tccgttcaat tcgcttttgt
     6601 gcattgggat cggcgcaatg tttttgatcc aagtatttgt caatcttgga ggaattactg
     6661 gcgttattcc tttgacaggg atcacgttcc catttttaag tcaaggaggc tccagtttgc
     6721 tgatgctttc gatttgtgtc ggctttgtcc tcaacatcag tgcggatgaa aaacgcaaga
     6781 gcttaggttt ataataaaaa aagatgtagg agtggttcga tgaaaaaagt tttagttgct
     6841 aacaggggtg aaatcgctgt acgtgtattt cgtgcttgta cagaattagg aattaaaact
     6901 gttggaatct atgcagaaga agatgaatat tccgtacacc gtttcaaagc ggatgaagca
     6961 tatttagtag gacaaggaaa aaaaccgatt gatgcgtatc tagatattga agggatcatt
     7021 tctatcgcga aagaatgcgg agctgacgct attcatccgg gttacggtct tttgtcggaa
     7081 aacttgaatt ttgcgcaacg gtgcgaagaa gaaggcatca tttttgttgg acccaaactg
     7141 catcatttag atatttttgg agataaaatc aaagcaaaag ctgcagctat cgaagcgggg
     7201 attgcttcga ttccaggcac agatggacca atcgcttcta tagacgatgc cttggagttt
     7261 gcgaaacaat acggttatcc gattatgatc aaggcagctc taggcggcgg cggacgcggc
     7321 atgcgtgtag ctcacgatga aaagagtgca agagagggct acgaacgtgc gaaaagcgaa
     7381 gcaaaagcag cctttggtag tgatgaagtg tatgttgaaa aatacatcgc taatcctaag
     7441 catatcgaag tacagattct cggggatacg catggaaacg tcatccatct ttttgaaaga
     7501 gattgttctg ttcagcgccg tcaccaaaaa gtagtagaag tagcgccttg tgtctctatg
     7561 aatgaacagc aacgtcaaaa aatctgccag gcagctgtcc aattgatgaa atatgtcggg
     7621 tatgtcaacg caggtacagt agaatttctt gttgaaggag atgattttta ctttatcgaa
     7681 gtcaaccctc gcgtccaagt ggaacatacg atcacagaaa tgattacaga tattgatatc
     7741 gtaacaacgc aactgttgat tgctcaaggt ttggatctgc ataaagaaat cggattgcct
     7801 cagcaagaag gaattaaatt aaatggttca gccattcaat gccgaatcac tacagaagac
     7861 ccgttgaata actttttacc agacacaggg aaaatcgata cgtatcgttc acctggtggt
     7921 tttggcgtac gtctggatgt cggaaatgct tacgcgggct atgtagtgac accgtatttt
     7981 gattcattgc tagtaaaagt atgtacgcat ggtgctacct ttgaaacagc cattcagaaa
     8041 atggaacgtt gcttgaaaga atttagaatc cgtggagtga aaacaaacat tccatttatg
     8101 ctcaatgtca tcacacatcc tgaattccaa tcaggaaatg caaaaacaac cttcattgat
     8161 agtacagcaa cattatttga atttcctcga ctacgagacc gcggaaacaa aacgatgaaa
     8221 tatatcggtg aaattactgt gaatggtttt ccaggtatcg aaagtggcga aaaaccattt
     8281 tatgaagaac cacgtatgcc taaagatcta atcacaagaa ctgattacgt aacggctaag
     8341 aatgtattag atgcgaaggg tgccgatgct ttggtcgaat ggatcaaagg acaggaaaat
     8401 ttgttgttga cggatacgac atttagagac gcccatcaaa gtctgctagc aactcgtgtt
     8461 cggacaaagg atttcaagca gattgcacgt ttgactggag aaggtcttcc tgaactcttt
     8521 tcaagtgaga tgtggggggg agcaacattt gatgtggctt accgcttttt gaatgaagat
     8581 ccttggcaac ggttgagaaa aattcgttct ttaatgccta atacgttgct gcaaatgctt
     8641 ttcagaggtt caaatgccgt tgggtattct aattatcctg acaatgtatt ggtggaattt
     8701 gtcaaagaag cagcagcgca aggaatcgat gtatttcgaa tctttgatag tttgaactgg
     8761 actccacaaa tggaaaaaag tatccaagct gtacgggata ctggtaaaat cgcagaggca
     8821 gctatttgct atactggcga tatcaacgat ccaagtcggg caaaatacaa tgttcagtat
     8881 tataaagaca tggcaaagga actagaacaa ctgggtgcgc atatcattgc aatcaaagat
     8941 atggctgggc tgcttaaacc gcaggcagct tatcgtttga ttagtgaatt gaaagaaacg
     9001 acagatctgc caatccatct gcatactcat gataccagcg ggaatggaat catcacttat
     9061 tctgctgctt caaaagcagg agtagacatc gttgacgtgg caatgagtgc aatgagtggg
     9121 aatactagtc agcctagcat gagcagcttg tattatgcac tggtcaatgg tccacggctg
     9181 ccagaaatca cgattgaaaa tgcacagaaa ttaaaccatt attgggaaga tgtgcgcatg
     9241 tattacaaac cgtttgaaaa cggcttgaat gctcctgaaa cagaagtata tatgcatgaa
     9301 atgccaggag gacagtattc gaatctacag caacaggcaa aagctgtcgg attaggtcat
     9361 cgctgggatg aaatcaaaca aatgtatcat actgtcaact tgatgtttgg cgatatcgtt
     9421 aaagtaactc catcatctaa agtagttgga gatatggcac tatttatggt ccaaaatgat
     9481 cttacagaag aagatattta tgaaaaaggc gaaacactaa gtttccctga atctgttgtg
     9541 actttcttcc aaggagaact agggcaaccc gttggcggat ttcctaaaaa attgcaaaag
     9601 attattctta aaggcagacc tgcattgaat gaacgtccag gtcttttggc tgaatcagtc
     9661 gacttcaacg aagtaaaaaa agaattggca gaaaaaaatg gctatgaacc aaaacaagac
     9721 gaagtattaa gctatttgat gtatccgcaa gtctttttgg actatcaaaa agcatataat
     9781 caatttggcg atgttacatt actggacaca ccaacatttt tccaaggtat acgtttgggt
     9841 gaaacaatca atgtacaaat cgaacgcgga aaaacgctta tcattcgttt agatgaaatc
     9901 ggagaacccg atatcgaagg gaatcgcgta ctgttcttca atttgaatgg acaaagacgt
     9961 gaaatcacta tcaaagataa ttcgatcatc agtacggtcc aaacccgatt gaaagctgaa
    10021 ccgacaaacc gagaacaaat tggagcaacg atgtctggtt ctgttttgga tgtattagtg
    10081 aaaaaaggcg ataacgttaa aaaaggtgat acgttgatga ttactgaagc gatgaaaatg
    10141 gaaacggcca tcgaagcacg ttttgacgga gaagtcgcac atgtatatgt gtcttcagga
    10201 gacactattt cgtctggtga ccttttgatt gaagtgactg agaaataata agcgaaaggt
    10261 ggggaaacat gaaaagactg ggtttgtttt ggctgattct gctattagtt attgtggcat
    10321 tctacatgga accagtcttg tttccgccaa aacttgaagt gaaggaaaac tctgatcaac
    10381 aaatatcaaa ccaaatgaca acgtggaaat accaggagct taaagcaact ggtttttcta
    10441 cttatatcgg aaaaccgatc gatcagctgg aaaaggattt tggccaagcc tatgatcgat
    10501 taactagcgg atttggtttt gaaacaagat attatgaaaa taaagctagt catctcacat
    10561 ttgaagcgaa catccaagac agcagagtca caactgttaa agtactgcaa acagggcctg
    10621 ctgatatcgc gccgttttat ttagggatga cgatgcaaga tcttacgaaa atcactacta
    10681 tctatactaa tttcactttt gagtaccatg atacagaagt tggaatcgaa ctaatggaag
    10741 aggatatgaa ttatcgtccg ctaattgctt ttgataacga cacttttgct attttatttt
    10801 ttgatcaaac aacaaacggc ctattttcag ttgtgtattt agataaagat agtcttttga
    10861 aactattgcc atatcaagtg tttggtgaag gccttccaca ttatcaagca gataaatcgg
    10921 ctgattggga atcaatcaat cgcgttaaag aacgaaaaag tacgacttta ttaaatatgc
    10981 ttagaagaga agacgaactt cccatataca atcaaacact tgcctttcaa aaccacagtc
    11041 agctgctact acatgatttt ttgacaaggc ctgaggaaat attgtcagag gaacgtatgg
    11101 ctgattggca aaaatcgcta ggcagtgctc aaacgacagt gaaattttca ctgacgaatg
    11161 atgaattgga gaagttaatc agtaaacaaa aattagaaaa tactagtggg ctatttattc
    11221 atccggcgat tgacgctact ttttcgtttt tatattggta cagcgatcct tacaaccatg
    11281 accgtttcat ggacccggga acggattctg taggcattgc tttttctaaa gaaaatatgt
    11341 tagtcttatt gcaagaagaa aacggagaaa gtagtgatag cagtgatcgt taacgaagag
    11401 ctgtttcaac tggaggatca atgcctccaa gtcgctgaaa tgataaaaaa gagtaaaacg
    11461 atggcttctt atcttgaaca taaacagtca atggaagaat ctgcaaaagt ttgccagttg
    11521 aaagaagcgt tcttgtctaa gaaagaagca tttgaaaatg tagcggcata tggtgagtat
    11581 gcacctgatt atcgtgaaaa aaaacgagct gttcgaaaag caaaaagaca gcttgatatg
    11641 gatgagcatg ttgcagcttt ccgatatagt gaaacacagc tgcaaagtct gttggatcaa
    11701 attgtccaag tacttgccga agaagtttct aatgaaatca aagtagatgc aggtagcccg
    11761 ttttttgaaa cgaaaaaaca ctttggatgc ggaggtaatt gtcatgcaat tagacaatag
    11821 tgaatttgaa ataacaaaac gacgcgggct gatcgtatgg gtctacagct taaaacaatt
    11881 aaagaatctg aaaaagttcg gcttgttgca ttatgtctca agaagaatga aatatgtcgt
    11941 gctttactta aatgaagaga cattggaaga aacagaagaa cgaatccgta aattacattt
    12001 tgttcgaaac gtagaacgtt cttaccgacc ggatatcgaa atgaattttg ccgaaaaaat
    12061 aggaaacaaa acagtattaa aagacgaagg tttcgaaatt gaagagctaa atacagaaat
    12121 ccgattagct gaacatcttt aaaaatctct tatgagcagt ttttaaataa aaaataactt
    12181 ggataacgat cgatttttga tcattgtcca agtatttttt tggtatacta gtaccagtac
    12241 catttctaag gagtgagtag atgcggataa tatcaggaaa ttatggcggg cgccgtttaa
    12301 aaagtttagc aggggcgaac accagaccaa ctacagataa agtaaaagaa tccatattca
    12361 atatgattgg accatatttt gatggagaga cagtattgga tctgtttgca ggaagcggtg
    12421 gtttagctat cgaagcagta tctagaggct gcagtcatgc ggtatgcgta gacaaaaatt
    12481 accaagcgct aaaaatcatc aaagaaaaca tcgaaattac gaaagaacca gagaaattta
    12541 ccacaataaa acttgatgcg gacaaagcaa tcgaacggct agcagcggag aaacaacaat
    12601 tcgactactt gtttcttgat ccgccatatg caaaacaaaa aataatcgat caaatccata
    12661 aaatggaaga actgggactt ttttctaaaa ccgcagttat cgtatgcgaa acggataaaa
    12721 cagtcgaatt gccagaaact gtggctggat tccatcaaat aagaaaacag atttatggca
    12781 taacggccgt aactatctat agaaaagagg gaaatcaatg aaacgtgcat tattcccagg
    12841 aagttttgat ccttttacaa aaggtcactt agatacggtg gaacgtgcgg ctaaattatt
    12901 cgatgaggta gtaattggtg tttttatcaa tacttcaaag aaaagtttgt ttcccccaga
    12961 agaaagaatg acattgatca caaaagctgt ttctcatctt cctaatgtaa aagtcatgca
    13021 tcaagaaaat caattgacgg tagaaacagc aaaagagatt ggtgcagatg cgttgatcag
    13081 aggcatacga agtatcaaag actttgaata tgaacgagag attgctcaga tgaatcatca
    13141 tctatatgat gaattggaaa ctgtcttctt attagcaaaa ccagaatata gtcacgtgag
    13201 ttccagtatt ttaaaagaag tactgcactt tggcggagat gtgagcagct acttaccgcc
    13261 agtgatcaac gaagctttag ctggaaagcg tgaatcaaat gaaagctaaa caatggttga
    13321 aaacagtact gattatcata tttggaatgt tgatcattgg atttgtagta gttcccttgc
    13381 cgtattatgt agaatcaccg ggagccacga tcgatctgaa agaactaatt acggtcaatg
    13441 ataaggaaga taaaggttct gggtctttct ctcttacctc tgttggtatc aggcaagcta
    13501 caggtttctt agctttaaaa gctaaaatga ccccttttga agaattgatc agtgaagaag
    13561 aattgactgg tggggcgaca aatgaagaat ataatcaaat gcaacagtat tatatggatt
    13621 cttcccaaaa tgcagcaatc gaacaagcgt taaaacttgc agacaagcct tataaaatgg
    13681 aattcaaagg cgtatatgtc atgagtgtag agaaaacatc gaatttcttt ggcaagcttt
    13741 cagttggaga tacagtaaca aaagtagatg ggaaaagctt tcaaagtaca gaagcattta
    13801 tggattatgt aaaaagccaa aaagttggac aaacaatcga aatcagttat ttgcataatg
    13861 gtgaagaaaa aacagcttct ggtgatctga tcgagttacc aacagataaa aaggcaggaa
    13921 taggtatcac gcttactgac cataccgaga tcgaatcaga tacagatgtt cgtattaatt
    13981 ctggctctat cggtgggcca tcagcgggat tgatgttcac tttagaaatc tatgaacaag
    14041 tcactggtaa aaacttgcga catggtaagc aaattgcagg aactggaacg atcaacagtg
    14101 aaggagaagt tggccgaatc ggaggaatcg ataaaaaagt ggcaagtgcg gataaagctg
    14161 gcgtagagat tttctttgca ccagatgata cgatttcaga cgatgttaag aaagaatatc
    14221 ctgaaataaa aaccaactac gaagaagcaa aagctgccgc taaaaaattg aattcctcaa
    14281 tgaaaatcgt accagtaaaa acagtacaag aagcgcttga ctatctagag aaaatgaaat
    14341 gaaactaaat aattaaagag gggttgtgac acgagttctg tcacaacccc tctttttcgt
    14401 caaaaatctt cacgataaaa ataaaaacaa aagaaaaaat tgacgtaatt agatgttgaa
    14461 gggacgattt tgccagagct cactgtttct tcaattttaa atgaaaggag taatgaatga
    14521 tttttactgg tcattctttg aaaaaagaac aatgatagaa aaaatcagca agaaaatact
    14581 agcttcaccc aaattgatca tttggatgtc tatgatagtt cttatctttt gtatcgcaag
    14641 tggtttttta ttatcaaatt tgctatttta tagagaaaca gaagagactg ctgcaaaaga
    14701 aatactttct tcgtttagtt ccagtggaga agatccatca gctgaaggaa acgatgtaga
    14761 agaggatgct cgtccaaagg tcatgtacac cgatatcaaa ggaagtgtga aggagcctgg
    14821 tatctattcc ttttcttcag aagaacgggt ctatgatgta ctaaagcgtg caggtggatt
    14881 attagaagaa gcggatagcg atcgaatcaa cttttctgcg aagatagaag atcagcaagt
    14941 cctatatatc cctgctgtag gtgaagagct gccagaacat cttgatcagt tggcatcctc
    15001 ggaaggaaaa cagcctacag cagattccga gcctcccaaa ataaatatca atacagccac
    15061 tccatcagaa cttcagcaga ttcctgggat cggatcagtc aaagcgcaag aaatcattcg
    15121 atttagagaa gaaaacggat ccttccagaa agtggaagac ctgcaggaga tttctggtat
    15181 cggtgaaaag acagttgaaa aactaaaaaa cttcgttaca attaaataga atgattcaaa
    15241 atcgactggc acgagcaata aatggacgct aatggatact aagaataatc caattctaag
    15301 agcttggcag gacgaggagg tagtattttt ggataggaaa tagcttgatt gttcgcaaag
    15361 aaacattaaa aaaaccaatg ctgaatgtct atctccaaaa taaaatatct gggattcata
    15421 ttatgaatac ggctgtcagc ggcaataaca gtcaagctct acgagaacgc tttgccaaag
    15481 atgtacttag ctatacagca gataaagtat ttattctcat tgggacgaat gatctagcag
    15541 agcataaaca actttctaaa gaaacgtacc aaaaaatctg cagtggatga tagttcagct
    15601 gaaaaaagac tatagttctg atcatgcttt ctttatcacg ccaccagcag tcgatgagac
    15661 aaaacaaaaa tatcggaata acaagttgat caaagaatat atctctgttc tcacagaagt
    15721 agcaaaacgc catgattgtg aagtatcgat ttttatacgg aatttcttga acaaatggat
    15781 tcgaagaatt tttataatgg gctaatggat gacggacttc atttcggcag tgaagggtag
    15841 gatcttttgt cagacaggat gattcgttat atttaaagaa tattttgttt aagcaatgag
    15901 tactttttaa tcaacttgaa aaaacggagg aatataaaac atgttagaaa aatcttcaaa
    15961 agcatgcgat acgaataaag aaaaagttac tgataagtca cataatgaac gcattccttg
    16021 ggaccagtac tttatggctc aggcagtact gttatcttta cgtagtacgt gtacacgttt
    16081 agaagtagga gcgacactcg ttcgagaaaa aaggatcatt gctggcggct ataatggagc
    16141 agtcagtgga gatgtccact gcatagatga agggtgttac gtcgtggatg gacactgctt
    16201 gcgaacgatc catgcagaga tgaatgcact cctacagtgt gcaaaacttg gtatcccgac
    16261 ggaaggttca gaaatctatg tcacacattt tccatgtttg gcctgtacaa aggctttgtt
    16321 gcaagctggt gtgaaaggga tcaattatct ccatgactat cgaaatgatc cttatgccca
    16381 agcgttgatc gaacaattag gtgtatctgt acaccaagtt gctttagact cacagcattt
    16441 ttcaaaactt caaaatgaat taacaggaaa acatgtctag cgttttagaa aggcatgttc
    16501 gaaatcggtt gatttttccg gcaattacgt cgatgattat ctgtttgttg tattacactg
    16561 acaattgggg ttatcgtttg cttcttgccg gaattttttt atggttttcg ctaaaagaag
    16621 gacgttttat cgcgtacttg tgtattttgt gtagcataac ggtatccatt tcttataggc
    16681 tacaagagta ttcattttta gaggaaaaaa caacatctgc gcaaattact gtatttacag
    16741 atacgattcg tgcaaatggt aattttttga caatggaagg aaggttatca gagaataaac
    16801 aaaagctcca gctttcttat caagtaaaca cagaagcaga attgaaaaca tggcttaact
    16861 tccgaggaaa gggaatagaa ttgactgctg aaggcgagtt catctctcca gcaaaaaagc
    16921 ggaatcttta taattttgac caagaagctt acttcaggaa ccatagaatt tctggacggt
    16981 tccaaattca aaagattgaa cagatcacca tgcaaaatca ctggcgaaac tggcttcaga
    17041 gaaaaagagg atcttttatc tcctttgtcc aatctgaatt tccgcaaaaa acaagtgtat
    17101 atattaattc tttattatgg ggctataaag atgcaggatt cagagaacca gaagaaattt
    17161 ttagggagag tggtttgctg catctgttca gtctatcggg tctacacatc caattttatt
    17221 tagggtggct gtattattta tttcgacgta tcggatggcc actacacgtc agtattattc
    17281 cgttgagtct actaactatc tgttatgttt ctattgcagg aagttctatt tctgttttgc
    17341 gtgctagttt gctgttttta ttgcgattgc tagtcaaatt gctgaataag cattattcca
    17401 ccatggactt atttgcagtt gtcttttggc ttcttttact atttgatcct cgatttcttt
    17461 ttcatgcggg tggacagctt agttttttca tgagtttttt gtttatcctg atttcttttg
    17521 atggagattg gttgaaaaaa acggcctctc acgtcctgtt tactatgatc acgatgccgt
    17581 tgattgtatg gcatttttat gagtggccta ttttaggtag tctttttaca ttactgattg
    17641 caccggtatt caagtttctt tttcttcctg gtgtgttatt tctcacactc ttcaatcgct
    17701 ggctgccgga aactttactt ttgctgatag aagagggatt aatcttattt gagcgaataa
    17761 tcgatttttc ttcagggtcg tctctcatta taggacgttt gccccttgtg ctatctggga
    17821 tgtatatttt cggattactg atttgtatgg ataggttgaa agaacaacct gtgaaacact
    17881 tgttttatgt tggtcttttt tcttttattt ttttgacttt gccattttta cgcttttctt
    17941 caacgatcgc ttttatcgat gtcggtcaag gagacagtat ctttttgcaa agtccttttc
    18001 gaaaagaaac gattttgatc gatactggag gtcagttaca ctttgaaaga gaaaagtggg
    18061 cgcaaggtat gatacgtcct cctgctgaaa gaaatatcgt tccatatcta aaaggtcagg
    18121 ggataagtgt aatcgataaa ctcatcttga cacacgacga tacggatcat gtgggagaat
    18181 tacccacgtt atctcagcat tttactatca aaaaaattta tatcggttgg ggcgctggac
    18241 gaaatgagcc attacaaagg catttatctg aagctcaaaa aaatggtact gagatcattg
    18301 aaatcaaaca tggggacagg atcagcggtt attatgatct ttatgtattg actccttttg
    18361 aaaagggaga gggaagaaat gaagattcga ttggtctatg gatggaatat aacaataggc
    18421 gctttttatt tttaggagat ttgaatcaag caatggaaaa acaattgctt ttgatttatc
    18481 ctaatctgaa agccgatgta gtcaaattag gtcatcacgg tagccgtacg tcaagtaaca
    18541 cagattttct ttcccatatt gaagcaaaac atgggattat atcctgcggc gtaaataatc
    18601 gttatggtca cccgcacagc gaagtattgg agacactaga agaaaatcag ataaaaacat
    18661 ggcgaacgga tcaacaagga atgatcacct atcgctggca tccagttttt catcctcatg
    18721 ggctagtgga aacaatgata gactagtaat tctcatctgc tcatggtagg ataatttttg
    18781 aaagtggtga gtaatttgag tatacaagca gagttacaaa aaatacgtaa agaaaaactt
    18841 gcatcttgtt acttgatttt aggaacagaa aagtttctcc aagatcaagt tcggacagaa
    18901 attgtcaaaa aaatccaatt agagggcgaa gatgacttaa attttttaag ttttgacatg
    18961 gaaaatgcaa gtttagatga ggtagtagct gaagcagaga cgttgccgtt tttcggagat
    19021 caacggttag tattcgtaga gaatccttat tttttaacag gtgaaaaagt aaacaatgga
    19081 atcgaacaaa atactgattt attgacggct tatttgaaag aaccattaga atcgactgta
    19141 ttagtattct ttgcgccata tgaaaagttg gatgaacgga aaaaagtaac gaaacaattg
    19201 aaaaaaacag caattatcat caatgtccaa cagttgaatg aaaaagaagt acgtcaatat
    19261 ctgatgaata ccttagagaa ttcctcaatc aaaatggaac gaagtgcaat tgatttattc
    19321 ttgaggttga ccgacttaga tttatccaaa atgatgagag agttacagaa attggtcctt
    19381 tatggacaaa atcaacagca aatcacggta agagaagtag aagaattagt tcctaaaacg
    19441 ttagaacata atatttttga catgacccaa tatattttaa aagggaagac ggaacaagct
    19501 ttgcgtttat acgaagattt agttatgcaa ggggaagaaa caatcaaaat taatgcgatt
    19561 ttgctttctc aattacgttt atttttacag acaaaatttc ttgtaaagat tggttatcag
    19621 caggcaaata ttgctgaaac attgaaaatc catccatatc gtgtaaaact tgccatgcag
    19681 gaagtaaaaa aattcgatga acatttgctg gtacagttgt ttgatcaatt agttgagatg
    19741 gattatcaaa tcaaaacggg acaaatcgaa aaagaattaa gttttcaact attcgttttg
    19801 cgcacagggc agttgttaag aaatcgataa gaagaaagac gagggcaaag catgcgggaa
    19861 ggtcgtttgt ttttgtcctt tttttgacaa ataaaaaaat cggccgaagc cgattctttt
    19921 atttagcgat ttttttgctt aaacgagatt tgtcgcggtt agctttgttt ttgtggatta
    19981 gaccttttga ttcagccata tcaatagctt taacagcttc tttatataac gcatctacgt
    20041 tgtcagcacc tgaagctaca gcatcttcaa attttttgat tgcagtacgc atagcgcttg
    20101 tttgagatga atttttcaca ttagcgtttt cgcttgtacg aacacgtttg attgcagatt
    20161 caatgtttgg cattagtttc acctccgata acttaagttc ttacgcgtgt taccgcataa
    20221 ttcaacattc attattatac ctaaaggcag cgtgctttgc aatatgaaca tgacaagttt
    20281 ttttccttaa cagtctttta ttaggatttt ttttcagtaa aaacggatag tacaagctga
    20341 aaaaaatcaa aaagacgcta ttgtgggagg caatagcgtc aaaccaaact a
//
LOCUS       DAMEEU010000053        20186 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.054, whole genome shotgun sequence.
ACCESSION   DAMEEU010000053 DAMEEU010000000
VERSION     DAMEEU010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 20186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.054"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            212..1018
                     /gene="proB"
                     /locus_tag="PB779_001923"
     CDS             212..1018
                     /gene="proB"
                     /locus_tag="PB779_001923"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HDE0739444.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1015..2262
                     /locus_tag="PB779_001924"
     CDS             1015..2262
                     /locus_tag="PB779_001924"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HDE0739445.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2338..2682
                     /locus_tag="PB779_001925"
     CDS             2338..2682
                     /locus_tag="PB779_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739446.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2799..3125)
                     /locus_tag="PB779_001926"
     CDS             complement(2799..3125)
                     /locus_tag="PB779_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739447.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3498..4700)
                     /locus_tag="PB779_001927"
     CDS             complement(3498..4700)
                     /locus_tag="PB779_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0739448.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4817..5332
                     /locus_tag="PB779_001928"
     CDS             4817..5332
                     /locus_tag="PB779_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDE0739449.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5531..5977)
                     /locus_tag="PB779_001929"
     CDS             complement(5531..5977)
                     /locus_tag="PB779_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDE0739450.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6024..7502)
                     /gene="msr(C)"
                     /locus_tag="PB779_001930"
     CDS             complement(6024..7502)
                     /gene="msr(C)"
                     /locus_tag="PB779_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDE0739451.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            complement(7856..8485)
                     /locus_tag="PB779_001931"
     CDS             complement(7856..8485)
                     /locus_tag="PB779_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDE0739452.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGVEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8469..8933)
                     /locus_tag="PB779_001932"
     CDS             complement(8469..8933)
                     /locus_tag="PB779_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDE0739453.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9420..10688)
                     /locus_tag="PB779_001933"
     CDS             complement(9420..10688)
                     /locus_tag="PB779_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HDE0739454.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10919..11656)
                     /locus_tag="PB779_001934"
     CDS             complement(10919..11656)
                     /locus_tag="PB779_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0739455.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11723..12292)
                     /locus_tag="PB779_001935"
     CDS             complement(11723..12292)
                     /locus_tag="PB779_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HDE0739456.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLLVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12420..13292
                     /locus_tag="PB779_001936"
     CDS             12420..13292
                     /locus_tag="PB779_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0739457.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13634..14506
                     /locus_tag="PB779_001937"
     CDS             13634..14506
                     /locus_tag="PB779_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDE0739458.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14503..16461
                     /locus_tag="PB779_001938"
     CDS             14503..16461
                     /locus_tag="PB779_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0739459.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16712..17563)
                     /locus_tag="PB779_001939"
     CDS             complement(16712..17563)
                     /locus_tag="PB779_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0739460.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17686..18153
                     /locus_tag="PB779_001940"
     CDS             17686..18153
                     /locus_tag="PB779_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HDE0739461.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18416..18898)
                     /locus_tag="PB779_001941"
     CDS             complement(18416..18898)
                     /locus_tag="PB779_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HDE0739462.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18998..19861)
                     /locus_tag="PB779_001942"
     CDS             complement(18998..19861)
                     /locus_tag="PB779_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HDE0739463.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6070 a         4157 c         3663 g         6296 t
ORIGIN      
        1 aaactactcc tattctaaca tatccgaggc tgtaaaagac tttctttaca aattcttcaa
       61 gaaattctgc tatcttaaag taaaccatta attcgttctt tttccaaacg actacaagtt
      121 gtacaaaaaa actatttttt acatgacttt actcgtcaaa acaagtagaa tagaacgaaa
      181 ttaatgagtg gatatttgat tgaggtgtca catgcgtaaa gaaattaaaa atgcaaaacg
      241 aattattgtc aaagtaggaa caagtacatt gatttatccc aatggaaata tcaatcttgc
      301 ggcaatcgat cagttagctt ttgtcctttc tgatcttaga aatcggggaa aggaagtgat
      361 cttagtctca tcaggagctg taggcgttgg tatgcataaa ttacatttgt cagaacgtcc
      421 gactttgatt cctgaacagc aagctgcggc ggctgttggt caagccgaac tgatgaatat
      481 ctataatcaa agattcagtg tatataatca acagacggca cagatcctcg tgacaagaga
      541 cgtggtagat tatcctgaaa gtcgtaaaaa tgtgaggaat acattggaac agcttttgat
      601 tatggacacg atccctatcg tgaacgaaaa cgatactgta gcagtggatg aattagatca
      661 tctgacaaaa tttggcgata atgatcagct gtcagccatc atggcaaaac ttgtcgcggc
      721 agaccttttg atcgtccttt ctgatatcga cgggttttat tcagataatc cgactacaaa
      781 tcccgaggct cagatgtatc gctatatcga taaaatcgat gaaaagattc tggcacaagc
      841 aggtggtgct ggtagcacat ttggaacagg cggtatgcag agtaaattaa aagccgcttc
      901 taggatattt gaagcaaaca gcgcaatgat tttagcaaat ggaaaaaatc cggcaattat
      961 ttttgatatt cttgcaggaa aagaagtagg tactttattt aaggaggact tgaaatgact
     1021 gacttgatgc aattaggaca acaggcaaaa gatagcgcgc aacaactagc acttatgcct
     1081 acaaaccgca aaaatgagct acttgttcaa atggcacaaa ccatcaaaaa gaatcaacaa
     1141 gcgatcattg aagcaaatca taaagactta gaaaaagcag tcgaaaacaa tatcagtgaa
     1201 acgatgcaag accgcttgca gctgacacct gagcgaatca atgccatggc tacagagatc
     1261 gaaaaaattg cttcgttaga cgatcctatt ggaaaagtag atgagatgtg gacgaacacc
     1321 gacggattga gaatcggcaa aaagcgcgtg ccactaggcg tgaccggcat catttacgaa
     1381 tctcgtccaa atgtcacgac agatgcagct agtctagcat tcaaatcagg gaatgccgtt
     1441 atccttcgcg gtggcaaaga agcattcttc tcgaatcaat tattagtcca attattgcag
     1501 caagtactgg tcagtgctgg cgaatctcct tatgccatcc agtttgtcga tgatacttct
     1561 catgaaactg caggacagtt gatgcgattg acagaatact tagatgtgct gattcctcga
     1621 ggcggagcaa aattaatcca acgagtcaaa gaacaggcaa cggtacctat cattgaaaca
     1681 ggtacaggaa ataatcacgt atatatcgat aaagaagcac agttatctat ggcagtgaac
     1741 atcatcgtca atgcaaaagc ttcccgtcca tctgtctgta acgcggcaga aacattgctg
     1801 atccattctg agatcgcacc ttttttcttg ccagctattg aaaaagaact ggtagaacac
     1861 ggggtctctt tacgtgcgga tgctcgtgcg ttagaatatc tagagacggc tgctttagca
     1921 gaagacacag attgggatac tgaatatcta gattatatcc ttgctgtcaa agtggtcgat
     1981 tctttggatg aagcaattgc acatatcaat cggcataata ctaaacattc agaaacgatc
     2041 gtgacagata gttatgcggc tagtcaacgt ttcttaaatg aagtggacgc ggcggctgtc
     2101 tatgtcaatg cctccactcg ttttacagac ggatcggtat ttggttttgg tgcagagatt
     2161 ggtatctcta ctcaaaagtt gcatgcccgt ggtccaatgg ggttaaatga attaacttcc
     2221 acaaaatata tcatttatgg cgatggacaa atccgcgaat aatgtttcgt gtgaaacatt
     2281 attcccgcct tttgcctttt ttctgtaaag gttctatcca actagaaagg tgtcaatatg
     2341 tttgaaattt taatgatttt ttttatttac cttatttctc tgaatatcgc tgcttttctg
     2401 ggagtcggta ttttatccct tttctttcaa ttcaaaaaac gaagcatagg gagtcaacgg
     2461 gaaaaatggt cgcagtattt tgacaaaatc gggcaaaaag ggctggttac acgcttgcac
     2521 attagttaca tggttgcatt atgcttatta gcgacaatca attactattc ttttttcgat
     2581 cattcaatcg cttatacgat tacgctactg attgctggga tttttcactt atcttataaa
     2641 tatcagctga ataaaaacca cttgaatcgg actttccgct aaaaaatatc cgtacgataa
     2701 gtagagtgcc ttgaagatcg gcaaaaaact gccggacttt ttagaggctg tgacaaagat
     2761 tttgtcacag cctctttttc catataaacg gcgttcgcct accagctgcc tggtaaatct
     2821 gtttcctctt cgttaagaag cgaaaatccg tcaaatgttt cgccatcata ataacgaagc
     2881 agctcatcca tggacaagtt catcgttttt tctttttctt cttccgctga ttcagccagt
     2941 agctgttccc gatacacctg atacatacca gctatttttt gctgcatcgc ttttctagtt
     3001 tcaccttccg cattgattat tggcaattct ttgatatagc cacgataaat caaccgatca
     3061 tctgaaaatt caatgggtaa ttcaacgagt gtcaacccga cttcctgaaa atattcttcc
     3121 agcatctatt atccccccat tctttttctt aaatgaattt tagcttacct actgaaaatt
     3181 ttccagtttc attattttga gaaaaaaagg gaatgtgaca aaaatcgtgt cacatcccct
     3241 ttttccgaat aaatggtgtt cttctgccaa ctcctcaatc ataagtcaca atattcaaca
     3301 aacatgagaa actgtttttt gaaattgttc cttgtgattc agagttaaac gacagtctca
     3361 caacctcttg gtaaacggcg ttcaaaagct tgcatctgcg gtaataagcc caaccaaacg
     3421 aaaaatatga gaagctattt ttgtttggct gttcttatga cttgatgcag gacagctttt
     3481 tcacaacctc tgatttctta ttcttcttca tttgtagcaa aataattacg gtgataaatg
     3541 atacaacata cactgataag aacaatggca cctgcaaaat aaaacgcata gctttcacca
     3601 atatgttcac caatcacacc tgcaataaat ggtgctaaag ctccaccgaa aaagcggaca
     3661 aaactatagc tggacgaagc aacgtttcgt tgcagacctg gtatttccat agcaatcgtc
     3721 gtcaacagtg tattgataat tccttggaaa aatcctgcta acacaatgct gatcggtaca
     3781 aggactggca tagaagttcc agctcctaat aacagcaaac aaataatgaa taagacaaat
     3841 gctgctaaaa ttgtccgata agtcgtaaac ttccgctcaa gagccggtgc aacgaaaatc
     3901 gaagcaatag ccagaagcac accccagcca aaaaatacaa aaccgacttc taattcagaa
     3961 tagccaatca ataaaaatgg cgcatacgca agtaaagtaa agaatccgaa attatataac
     4021 aatgcgatta gtccaactga acgaagttta tgattgctta acgctttgac accttcccaa
     4081 aggcctactt ttctctttgg tttctcagtt tcaggtaaaa gtaccgctag ggctataaaa
     4141 ccgcaaaaca tcaaaaatgc taccccaaaa aatggataac gccatgaacc actgcccaag
     4201 accccaccga ctagagggcc aacagccatt ccgcagccaa gtgctgcttc atacatcatg
     4261 attgcttttt ctgtgttacc aactaaaata ctgacgatcg ttgctaaagc agtagagaca
     4321 aataaagcat tcccgacacc ccagccggca cgtaacccaa tcagcattcc gatattccca
     4381 gataatccgc caagaccagc gaatacaacg atgataaaca atcctgtcat caatgttttt
     4441 ttcaaaccga tccgactaga taagaaacct gtaaatagca tcaccacacc agtgactaac
     4501 atgtaactag taaataacag ggtcgtttca gctggcgtag cgtttaactg tgcagcaatc
     4561 gtttttaaga ttgggtctac tagacccact cccataaaag cgatcataca ggtagctgct
     4621 acaactagcg ctgaactttt cccctttgtt tcttcatttg tttgttcttg tatatctatt
     4681 tgattctcca atatttccat ccctttctct ctattagcat catacatgat ttattttaca
     4741 tgtaaatatg cacatgtaaa acgtggaaac tttactgtga tataataaag aaaataagac
     4801 gagaggtagg atttttatga atactttagc ctatatatta ttatgcgtgc ttttatccaa
     4861 accacgttct gggtatgaat tgaagcagct gatcacaatt ttttgggaag cccatcacag
     4921 tcagatctat acaacgcttg ccaagttaga ccagcagggt tatgtgaccg ttttggacaa
     4981 agacgagcac tctcaaaaaa agatctacca cttgactgat gaaggacgtg ctcttgtaga
     5041 ggaatggatc aaagaggaaa ctcccgctcc tacgcaaaaa gatgaatttc tagcaaaaat
     5101 ctatgctttt tcgacgctcg ataaaacaac agctactgga ctgctattca ctagagaaca
     5161 acagctgaac aaaatcatgc aaaaaaatca aaaaaaattg aatgacctct cgctagacaa
     5221 gaaacaagaa tttggacgtt atgttgtgat ccagcgcaga attatgcttt gtcagcagga
     5281 actccaatgg tgtcagcaag taagagaaca aatgcagcag ttttttgagt aagggataaa
     5341 cagaaccttt ctagaaatat ctattgaaga gcaaattatc ttcaataaaa gagcaataca
     5401 gttggaaaag aaaaagcgat ccgaacgaca ggccaaaacc tatcgttcgg atcactattt
     5461 ttctagaact gcattcaaga gactatgaca aaaagcatgc caaggccttt tttcaaataa
     5521 cagtgttcca tcattcatta ctttgaattg cttttagcac acttcttgaa agcgggccaa
     5581 cgatgatcaa ctgcaacggt aaagcggcaa tcacattcat tttccaagca ttcatataag
     5641 cagagaataa ttgatcaggt attccttgtt ccatgatcac accgaataaa gacatacatg
     5701 tcaccattcc taaaaccatc aagcatgaaa tagttaagat catttggacc ttgctttctg
     5761 gatttactgg tagtttaaag gcaatttttt tcgccagcac accgatgatg aagacatcca
     5821 aaatgaaagc caccacgaat ccaggcacta gaccaatcaa caaacttgat aaatgaagat
     5881 cttgatgcag ccataaatta tacgcgctca tccccaagac catcaaaaaa cacatcattg
     5941 ttgtaaaaat tattccttct tttttatttg taggcaatct gtaccactcc tttaaatttg
     6001 tcacgaaaat catcgtagca catttaaaaa tttctcgtaa gtactttttt tattttctgc
     6061 ccttttattt cataaacttc atcagccgta cgctcgacaa agtaagaatc atgagaagta
     6121 aacaaaatcg ttcccggata tatttgcatt agcttctcta aagcttcgat cgttgccata
     6181 tcaataaaat tagtcggttc atctaacagc aacacattac ttggcttagt aaaaagcaaa
     6241 gcaatcgtca gacgggtcgc ttctccccca cttaatgtac ataacggttt cgtcaaagtt
     6301 tcctgagcaa accctaagtg attcagcaaa ctacggacaa gcgattctga aaactctgtt
     6361 tgtctcatga caaaacgaat gatggattct tcagatgtca tttgataacc cttttgctga
     6421 tatacttgaa agcttacttt cggagagaga aggattcctt ctccttgttt gcggatatgt
     6481 tctaataagg ttgtcttacc tgaaccattt tcaccgacaa tcgcgatttt tttacctaaa
     6541 gaaaactgaa aatcaccatt taccagtaat gttctcccac ttctttccaa ttggacattt
     6601 tgtcccatga tgggatagcg gctgtggagt tcaagagatt ttggtactgg aaaacggatt
     6661 tgtttcatct gctgcggctt ggttgtttct cctatttttt ggagtcttct ctctaatgtt
     6721 ttcgcattct tttggatggc tttttgtaca ctgtcttttt gtttagagga agacaaccga
     6781 tccggtctga tttgttgctt tttcttttta ctggacactt tttccaactt ttccgcttgt
     6841 tttttctttt cttggatcga tttttccaat cgttttttct ctttcatgat cgactctgct
     6901 tctcgtagct gagtcttttt ctccaattcc ttttgagtga gataggcact ataattcccc
     6961 gaaaactctc ggatttctcc gtcttttact tcccagattt tcgatgctag ctcatctaga
     7021 aaatagcgat catgactaac aaaaaccagc gtaccataat aataacgaag ctcttcaatc
     7081 agtcgatcaa tactttttct atctagatgg gttgttggct cgtctagaag catcccttgt
     7141 tcataagaag aaagaagacg tatcaactcg atctttcgtt cttcccctcc gctccatttc
     7201 cgctctgaag tttcttccag tcttaactgg aaatgactgg ctaattccaa atttaggtcc
     7261 tttgcttcag cgagataggt taattgaggc aggtagttga aggtgatctc tgtttggatt
     7321 ttcccatgat cgggaaaaag ttcaccggct attagtttga gcaaagtcga tttaccgaca
     7381 ccattttctc ctatgatccc tatacgatct tgctgataga cacgaagaga atcaatagat
     7441 agttctagct ggttgccaaa gctgacttgt agatttgtta tatttactgc taaattttcc
     7501 atatgtttta cactcctatt tcatgtaaaa caacaattat cgatactaaa aaagagcaga
     7561 aaaatctgtt tgcaaaaaaa ctgcatcaca tcttttccta ctctgaacga aataactatg
     7621 actaaatcac caaatctgtc atagctttca cctattctac tgtcgttcga aaaaatggac
     7681 atactccatc catgaaattg ttgtttatac atgtcttttg aatttattta gttgttattc
     7741 aaaagttcga aacgtaattt catcgatgca gtcatttttc cgacctcctt ttttattagg
     7801 ttaccacaca cgattcaaaa aaagcaatag ctactgaata gtaactgaaa accttttatt
     7861 cgaacgtagt gatcttttct ggtgctaaac gaacagactc gtaaccttct tctaccgctt
     7921 ttcctattga taaaataata actggaacat aacggtcttt atccaaacca aatgcctctg
     7981 ccaactgatc tgcttcgact ccaccaattg gatttgtttc atagccatga tcacgcgcaa
     8041 ctaacatgaa ttgcatagcc gctaagctag aatcgacttt gactacatcg ttcatttctt
     8101 ctcttgaaaa actcttgtaa taaggaatga tcgcagctaa ttgttgatct ctgacttctt
     8161 ttggcatctt ccctgattcg taagcttggt tatagatttc ttcgccatat tcgtaacatt
     8221 gcatatcgcc aaaaatcatg accattgcag aagaagtatc attttgtctc gtattgaaac
     8281 ggatcaaagg acgcaagatt tcttttgctt cctcgctttc agcgaccaca aagcgccatg
     8341 gttgcatatt gacagaagaa ggtgcagtcg tcgcttcttt gatcatttcc agcatttctt
     8401 cgtgtgggat tttgtatgtt tcatcatata cgcgaacgga tcttctacca gtcataattg
     8461 ttgaaaaatc atttttttgt tccattatta ttaacctctt tcgtttctgt tgttatattg
     8521 caaagttggg tattcaattt atctaaaagt gttagaaatt gtttcatttc tacatcgctg
     8581 aaagccgggg atagcacgga acctgtatct ttatggtcca tttcacaatg ctcgattttc
     8641 ttctgggctt tttctgttag cgctacatac acttcccggt tgttctgagg atttctctga
     8701 cgcgaaacat agccatttgc ttccaatacc ttcagatgac gagtaactgc tccttgatca
     8761 atctgcaact tttcttgcaa actgctttgt agcaatggat tttcttcttt cagtctcatc
     8821 atgatctcgt atctagtaag acttataccg atattttctt caaagatctg gacgattttt
     8881 tgatcggcta atttgatttg atataaaagg tgactaatct cttctaaaga cataatttcc
     8941 tcctttctaa taattgactc gtcaacgatt gacttgtcaa taatagaata aaaaaagaaa
     9001 aaagtcaaag aatcagctgt gtaataaaaa aaacgctctc aatagaaaag tatagagaaa
     9061 agaaattttt tgtagaatga acggaaaaaa tgataaagaa agcacaacgc taaaaccaag
     9121 attattgatt cttatcaaac tatagaagat agctcttctg cagtagaaaa ttttacaccg
     9181 ccaaaaattt ccgaaatcgc cttttgcaag aatcccgtcg aatattagaa attggatcag
     9241 tatgcttaaa cagtaataaa aaagttatga caagatgttg tcacaacctt ttttgagtaa
     9301 acggtgttca aaaacttgca tctgcggtaa taagttcaac caaacaaaaa acatgaaaat
     9361 ctgtttttgt ttggctgttc ttactacttg atgcagggca gctttttcac tacctctttt
     9421 taataaccat aaaatcctat tccttcatat ctccagccca tcggtgttag ccaatctctt
     9481 tccttagcac tcaaggtata gtgatgggta ccagtttttt catttggatt aaatagtcga
     9541 taaattggct tggaaccacc agaataaaaa cttagacctt cataacgcca accgattttt
     9601 gttaaagagt tgatctcaga ttgtgccatt gtgtaatgat ggtctccact gtaaggattg
     9661 tataaacggt agacaggttg tccgctgttt ggtgcttgcc aagcaatccc ttcatattcc
     9721 cagcctacag ttggcagata atttttttct ccggcattca atgtatataa atgttctcct
     9781 gtatgacggt tatacagacg atacatcgga gaagttgaag ttggtgctgt atcatactgt
     9841 gtcagattat aggtttcgat tacattgttc aatgtagaac cataattagg cgcagtggca
     9901 taacgacctg ttagccaagc cgtagcatct ttgtaagagt tcgtattgct tttccatgca
     9961 ccggaatagt agtaaacgcc tggctgaaaa gaagtcgtct tcaataccgt tacgttatct
    10021 tgcaatgatt ctttgtacga aggatatttt ctaaaagcgg cattcaccgt aatccattgc
    10081 ccattcacat attccgaagt aggcatcgta acagattggc cattatagct tcctttaatc
    10141 ccaaatagat tgtaattagg ggcagaagcc aaagtactgt tcccccagcc actttcaacg
    10201 atggcttgag caatcatgac tgatgcatat aagtcattgg cacttgccaa actttgtgca
    10261 gttgaggcaa tactatcaat gaacgcttgt tgagaattag cagatgagcg agcataaaaa
    10321 gcatagccag tatagttttc gaattcagac aaatctgctt gatgggtatg tgtcaatgtt
    10381 tgcccatctg tcaattggtt cgtgatttct tctgcattct ctggattgtt ctgagcttct
    10441 gctgatgtac tgtcttcggt ttgtgtttgt tctgttgttt cagttgttgg ttcttcggtt
    10501 gaaattgtat tttctgagac agtagctgac tgcaaagtac tctctgtatc gttttcaatt
    10561 cctgtttctg aagaactcga tgtctgagtt gcgacagttt ctgtcgattc ttcagctagc
    10621 actgttgtgt tggcaactgc tagatttcct aaaagaataa cgctaaataa taaattcttt
    10681 gctttcatct tttttctcct ttgaattatg aaacttttcc taaataacag tgtaactaaa
    10741 aaagtaaaag caagtcaatg tccatattta aataacattt gtttcttttt gataaatttg
    10801 ctttttctac ataaaaagac gtaaatgaag aatattcttc tccattcacg ccttaaattg
    10861 atggtcgttt gaataactat ttaacaagta attctctttg gatattatcc gttatggatt
    10921 atacttcctg tgtcgtcgga cggataatca tgttactgac agacatccgg tctggcgttt
    10981 ctatcgcaaa tgctacagca gaagctatat cttcggaggt caatccccat tctttttgcg
    11041 cttcatgaag ttcaagagca gcctttttgt cgctgatggt ttgatataat tcagtttgaa
    11101 cagctcctgg agagatgatc gtagatttga tgttattttg ccgttgctct tgacgtaatc
    11161 cttccatgat tgcacggaca gcaaattttg ttccgcaata aacggcggaa tcaggataaa
    11221 caacatgtcc cgccacagaa tcagttgaaa tgatatgccc agatttttgt ttttccatga
    11281 ttggaagtac ggcggaaatt ccatttaaca cacccatgat gttgatatca agcatatttt
    11341 gccattcatc acggtgacct tcaactaatg gagcggttgg catgattcct gcattattgt
    11401 acaatacatc gattcgaccg aacttttcca tcgctaaatc gataactgct tggacttgtg
    11461 caaaatctct tacatctgct gtttgaatat atagctcagc ttctggtaaa gattctttta
    11521 ttgcttttag gcgatcttct cggcgtgcag ctataactag tttagcccct ttttctgcta
    11581 atagcttcgt tgttgcttca ccgattccgc ttgaagcgcc catgatgaca atcacttttt
    11641 ctgataaatc attcattcta ttctcctcct gttttgaaaa atctcttgct tatactcact
    11701 atctcttatt tcatcttact gttcaaataa tccgttcgac aggtttgacg attttggcag
    11761 ggattcctgc aacgatggta ttgtctggga catctttcgt aacagttgca ttcgctgcaa
    11821 caatggcatt ctcgccaatc gttacgcctg gcagaatagt tgctcctgct ccgatccaag
    11881 catttttctt gatgtggatt ggctttacta acaagcctct tcgttctttt ggatcggtta
    11941 gatggttcac cgtgatgagg ttgacacgag gaccaatcaa tactgaatct tctaaacaga
    12001 tgccacctaa gtcaacgaac atcacttgac gattgataaa gacatttttc cctatactaa
    12061 tatgtttgcc gaaatctgta taaaaaggca gcagaacagt caccgtatca tctactttgt
    12121 cactaatgat attttctagc cgtttgcgga tatctgctgg ttcatggtac ccagtattca
    12181 gcgctgctaa aggctcttcg ttttcagctt ggatctgatg gatcacttca aagagcggat
    12241 ccgttactcg aatctcttta ttgacgattt gtttttcgat gaggcttgtc attttgctcc
    12301 ctccttttat ccttacttta taacggacgg cttatcatgt ctaatactta taaaacatac
    12361 ttaactattc cttttaacta tacttagtgg tatgcttttt taaaaacagg agggaaaaaa
    12421 tggatattcg tatactgacg tattttttag cagtagctag agaaaaaaat atcagccgag
    12481 cagcaaaatc tctgcatatc acgcaaccta ctctctcaaa acaactgaaa gatttagaag
    12541 aagaacttgg tgtgacactt ttcactcggg gctcccgaga gatacagttg acggattctg
    12601 gtcgatatct ttattcaaaa ggaaaagaaa tcttgtcgtt ggtagaaaaa acggcgaaca
    12661 atttaacaaa tgacgcaatc atctctggag aaatctacat tggcggaggc gaaactaaag
    12721 caatctcttt catttctgat agccttcatt cgttgatcaa ggcgcatcct gatatccagt
    12781 ttcatttata tagcgggaat gcagatgata tcatagacaa actggatagc ggattacttg
    12841 attttggact cgtaatcgaa ccgacaaaca aacaaaaata ccagtcattt cgactgccag
    12901 cccaagatcg ttggggactt ttgatacatc gaaatcatcc tttagcaaag caaaccgtca
    12961 tccatccgca ggaactgaaa actgttcctt tgatcatttc ccggcaaacg tcagtggaca
    13021 gtcaactagc tgaatggcta ggtttcagca tagatcagtt atcgatcgtc ggaacatata
    13081 acttattgta caatgcttct ttgatggtcg ataacgggac ttttggtgca ttagctctag
    13141 atgggatcat caatacttat gggacggaaa aaatattcat cccactcgat ccgccattac
    13201 aagcttcact gaatctcatt tggaaaaaag accagcctct ttctcctgct gctcgtaaat
    13261 ttttagatgt cctaacggag aaatacagtt aagtagagtt tttttccttc gctttcagct
    13321 ttttaacaac gaataagata agcaaaagat ccaacgatta aataacataa gtttcttaat
    13381 ttatttcttc cttttatttc tgataattcc agtaaattac tataattata aaaaaagaat
    13441 tgacaaaaca taactgtcta tataaaattg attacgttaa caataattcg tttcatgtga
    13501 ctagatcata ctaggcatga aaaatctctg aggaacatgg tttccctagg aggtttttcg
    13561 tgtctatttt tgtttggccg caatcaactg gtctagcaaa cgtgaaaacc aaatcttcaa
    13621 aaagggtgcg cgcatgaaaa tcaaaaagat ctttaatcaa aatgcagtat tggtagatga
    13681 cggtggacag gaaaaagtag ctattggaaa agggattgga tttgacagaa aaagaaatga
    13741 tttgattttt gatcgtgatg tcgaacggat atttgtcatg gaaccagaag gtcaaatcaa
    13801 gttgcaaaat ttacttaatc agattgatga acgcttttta tttgcagcag aaacgatcat
    13861 tgatcatgcg gaaactgttt tgatggaaaa gttgaatgaa catgtattga tcgctttgac
    13921 cgaccacatt gctttttctg cggagaacat taataacggt atcgtcatcc gcaacaaact
    13981 tttaagagaa atcgaagtgc tttacagtga tgaattcagt attgctcaat gggcagtaga
    14041 gtatctgaca aaagagcttg ggattccata tacttatgac gaagcaggat atatcgcaat
    14101 ccatattcac agcggacgaa gcggtcggaa caataaccat cgcagtatcc gtgaagtgac
    14161 gattgtatct gacatcatcc atttagtgga atcagaattg gaaacagata tccattcaga
    14221 accattttca ctgaattatt caagactggt gaatcattta cgactgcttc tacaacgaac
    14281 ccatgcgcaa caatatgctg ttttagacac ggaaatcgta gaaatggtca aacgaaaata
    14341 cccagaaagc tataagattt ctaaaaaaat ccgtgtgttg ctgaccaaag aataccagct
    14401 cgcgatcacg aaagaagaac tgggttactt ggccatccat atcgagcgtt taagaagcgc
    14461 aatcgtacaa acaaatgtta acaatcatga ggaggaaaaa aattgaaagc atatctacaa
    14521 cgaatgggac gttcccttca acttccagtt gcggtcttac ctgctgctgc tttactagta
    14581 gggatcggaa actggtgggc atcttatagt aacgacattg tcgctcattt tttacaagct
    14641 ggcggtaacg cagttttagg tcaattacct ttgctgtttg ccgttgggtt agcactaggg
    14701 atgtcagtgg acaaatcagg tgctgctgcc ttggcaggtt tggtcgcatt tgaagttcca
    14761 gtaaatgttt taaaaactga ttcagtagct actttattga atatcaaacc agaatcagtt
    14821 gatccatctt ttgctcagat cagtaacgta tttattggta ttattgccgg attgattgcg
    14881 gcagctcttt ataatcgttt ccacgaagca aaattaccga tggctttatc tttctttagc
    14941 ggcaagcgtc tagtgccaat cttggctgcc tttgtcatgt tgctgatcag tgcagtgcta
    15001 ctgctcgtat ggcctccggt ttactctgct ttagtttctt ttgctaaatt cattttgagt
    15061 ttaggctggg gtggtgcagg tctttatggc ttcttcaacc gtttactgat ccctacagga
    15121 ttgcatcaag caatgaactc cgtgttctgg tttgacgtag caggaatcaa tgatattggt
    15181 aaatttttgg cttctgaagg aacaaaaggc gtaacaggaa tgtatcaagc tggatttttc
    15241 ccaatcatga tgttcgggct tccagcagga gcatatgcta tttacagaaa tgcacgtcca
    15301 gaaaacaaag caaaaacagc ttccttgatg ctagcagcag cttttgcttc attctttact
    15361 ggtgtgacag aaccacttga attttcattt atgttcgttg cttggccatt atatgtcttg
    15421 catgcaattt tcactgggat ttctttagca gtgagtgcat tcttccattg gacagcagga
    15481 tttgccttta gtgccggatt tgtcgattac ttcctatctt tgaaaaatcc gattgcgaat
    15541 cagccattga tgttgatcgt ccaaggatta gtaacagcag tgatttacta ctttggcttt
    15601 aactttgcta tcaaaaaatt ccatctgatg actcctggcc gcgaggaagc agatctttca
    15661 gatgacgata ctgcaacgac taattcagac aataaatatg cggcacaagc aagcaaaatc
    15721 tacgctgcat taggcggagc cgacaatgta acttcgatcg ataactgtac tacacgcctt
    15781 cgtttgcaag tcaaagatac aggcctgatc gatcaaaata aaatcaaagc cactggcgta
    15841 cctggtatga agatcatcga cggaaaaaat gcgcaagtca tcgtaggtac agaagtacaa
    15901 ttcgttgcag atgagatggc aaaactacat ggtggtgctg cagcacgacc tgcacaaaca
    15961 aacaccgtgg ttaaaacaga aacatttgcc ggtgaaacga tcgaacaaga tatttacgct
    16021 atcgcaaatg ggaaactgat tccaatcact gaagtttcag atgatgtatt cgcggaaaaa
    16081 atgatgggtg acggctatgc tgtattacca gaaaatggag aaatcttctc tccaatcgct
    16141 ggtacgatca caaacatttt cccaacgaaa catgctgtcg gaatccaaac agatgctggt
    16201 atcgaagtct tgcttcatat gggcatcaac actgttgact taaaaggcga accattcact
    16261 ttatatgtag aagaaggtca aaaagtcgca agaggtcaat tgattgcttt agttgatctt
    16321 gccgctattc aatctgcagg caaaaacacg gatatggtcg ttgtattcac aaatggcgac
    16381 aaagtccaaa gcttagaaat cgaacccgca cgtgatgtaa aagcaaatga taaaatcggc
    16441 tctgtttcca acaaagcctg agccatcgtc ttccccagac ttttttatcg ataaacaaac
    16501 aggagctgag acaaaaatct tgtctcagct cctttttccg aataaaaacg gcgttctcct
    16561 gccaactccg cggtaataag tccagctaaa cgaaacatat gaagagctat tttttatttg
    16621 actcttctta ttacttgatg cagaacagct ttttcacaaa atttttcttc atactcaaaa
    16681 ctaatcggct ttttcacaac ctctttatac attattcctg atccaatatt tcttttaatg
    16741 ctgcttcaag agaagttaat ggttttccca atactttttc taaatcatca gaggaaatag
    16801 ctaactgatc ctttttaata tcatgttgga tcgctaaaaa catgtcagct gcttcttgag
    16861 ggaatccggc ttcttttaga ttttcgacaa acgctgcatc acttgcttca ataatttcta
    16921 actctttacc tgtcgcacgc tctaatgcct tggctaattc ttcatagtca gttagattgc
    16981 cggataattc taagatttct ggagagtcac tttctactag tacttttgct gcagcttctg
    17041 catattcacg tttcaatgcc caacctgttt ttccatttcc tgcagcataa acgaattgac
    17101 cagtttttaa agcctgccca atgataggta attcattctc tacataccaa ttattccgta
    17161 aaaatgtatg ggaaatacct gaatccttaa tcattttttc agtgaattgg tgatctggcg
    17221 ctaatacact gatcgagtga tcggcatctg caaaacttgt ataagcgata taagataccc
    17281 cagctgcttg tgctgccttc actacattct tatgttcggc ttgacgattt cctggaacgc
    17341 cagagacaaa aagcaatcga tctattcctt tcaacgcttc tttcattgag tctaaatcat
    17401 cataatcacc aatacgtata ttaaatccag cttctttcag tgcttctcct ttttcttcac
    17461 tacgtactag tacatagatt tcattttgtg gaaccatctt ttttaagaat tccagcgcat
    17521 aaccaccaaa acctccagtt gctcctgtta ctaaataatg catatttgcc actccctatt
    17581 ctttttattt gttaagattt acagctgtac atttataaat tacaccttta tcataaagag
    17641 tgtggtaaga taagtcaagc aaaaaaaatg aaaggatgac aactgatgaa gtattctctg
    17701 caatttagtg atgcaatcca tgtacttgcc tatattgaaa tgtttcaaga tacccgatca
    17761 ctttctagtg agatgattgc cagtagtatc gaaacaaatg cagcaaatgt acgtaaaatc
    17821 atgagtcagc tcaaaaaatc cggtttgatc tttacaaaaa ccggaaaacc gcagccttcc
    17881 cttgccaaaa gtccagatca gatttcttta ctagatgtct atcgcagcat cgaaggtaat
    17941 acacagctta tccaagtcga tccaaaaaca aatccaaatt gcgtcgttgg tgcgaatatc
    18001 caagaagctt tagaagaaag ctacgctcgg ctgcagaaaa aggcagaaga agaaatggct
    18061 aagatcacac ttgatagtct gatacataaa atagccgttt tggaaaaaga aaaaagacca
    18121 gaaaacacag gcctcgtaga gagattttta taattctctc tactgtgcct gcatttttct
    18181 gatcggaatc gtctacataa attcttttat tctccggggg acaaaagcct tgtcatgccc
    18241 ctttttcctc tctaatgctc aggtcaaagc gctgaagtca tgacgtcttg ataaacggtg
    18301 ttcaagtagc tgaccctcgg cattagttct gaaaaatgca aaatatggaa agctatttcc
    18361 catttttcct ctctaatgct caggtcaaag cgctactttc acgacctcta tattatcatg
    18421 gtttattgac taccggtatc cagatttctc ccatatattt cccgttggta actcccattt
    18481 cgactacagc atttggaccc ccaacatagg cgtaatcttc tacttctctt aaaacatgcc
    18541 caaaggccgt attcgtcaaa tcatttctta attcttcagg cgattctgct aaagcgctta
    18601 caacaagata cgttcctttt gggaatggga tgattcgcgt agtgtttgga acatcctgac
    18661 tcgtttgaac accgacatag tacatcattt tcccgttata gggttcgttg actgtaaaga
    18721 aataatgatt ttcagcagct tgtttcaatg catctattgt tccattaccg ataacttttt
    18781 gctcaaatgc ttgtttctct gcagccaaac cgacaaaatc cgtattgcta ctcttcaatt
    18841 ccacaccaat acccgtcacc gtaaaatctg gtttttcttc gatcctatac tttgccattt
    18901 ctcccaccct ttctattata ttaagttcat cttacataaa attaaaggga aatgacacga
    18961 ttacgctctt ttttctaggg atatttttat tttttaacta tttttttgct ttcactgcaa
    19021 tccaaatctc actgtaaaca ttactgaaat cctctcccca ttttgtaaaa gagatctcgg
    19081 gagcttcgac taacccataa tctgaagaag gaagccattc tgcatagatt ttcccccaag
    19141 tatcttgtaa agtttgggga aatggccctt tattaggaaa aatggcccaa gtgtgttctt
    19201 ctatagcaag catttctaaa tcagcgtacg gattttcttt tgtcgtagca aagccaatca
    19261 tgtgcatcaa actgcccttt tcttccaagc ggtctccatc aaatccataa gaaacgttga
    19321 ttacttgatt tggatataaa tctcctaact tatgcatctc ttccctttga gtctccgtga
    19381 tcgtctgcgc taacttttgt atttcttgat tgactccttc aaatttgaca ggaacttttt
    19441 tcgccacacc tgccacataa aactgttctt tcttttcgat acgaaattcc atcgattttc
    19501 ctcctctgac atcaataaaa aatgtcaagc gtggaaaaga tttttgtatg ccgtatctgc
    19561 tgatttctga aggcagatat cctgaccaat cacgaaaagc tcttgaaaaa ccttcgactg
    19621 tttcatatcc atatctaaac gccgtttctg tcactcttga tccatctaga agatcgcgat
    19681 tagccaaagc caatctacgg tttttgatat agtccattag cgacatccct gcaataaacg
    19741 taaagatgcg ttttaattga tattcagaga ttcctgtatt ttcggctatt attttatagg
    19801 aaagtccttc tgtcaaatgt tcttcgatgt aatcgatcaa ttggttcaga tctttaagca
    19861 tatttatctt cctccttgat tgccttttta tcatattatc aaagaaagtc aattacttga
    19921 tgaatcagga accaatttag tcagatgtag aaaatgttgt atggatctaa agaaaattct
    19981 caagcagcgt ttcgtaacgg ataattggta ttatctgcct atctatgttt tacctttaga
    20041 aaaataaatt ttggggaaga cagattctaa gtaaacaaag cggtaaaaat atcttttatt
    20101 cccttagtta atccgcttac tacctactgt acaaagcaaa ttgttgttca aactgctgat
    20161 cagaacgctg cttggatttt tctttg
//
LOCUS       DAMEEU010000054        19750 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.055, whole genome shotgun sequence.
ACCESSION   DAMEEU010000054 DAMEEU010000000
VERSION     DAMEEU010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19750)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19750)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19750
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.055"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(26..1552)
                     /locus_tag="PB779_001943"
     CDS             complement(26..1552)
                     /locus_tag="PB779_001943"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HDE0739464.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(1567..2214)
                     /locus_tag="PB779_001944"
     CDS             complement(1567..2214)
                     /locus_tag="PB779_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HDE0739465.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(2398..2727)
                     /locus_tag="PB779_001945"
     CDS             complement(2398..2727)
                     /locus_tag="PB779_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HDE0739466.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            2904..3632
                     /gene="sfsA"
                     /locus_tag="PB779_001946"
     CDS             2904..3632
                     /gene="sfsA"
                     /locus_tag="PB779_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HDE0739467.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            3648..4661
                     /locus_tag="PB779_001947"
     CDS             3648..4661
                     /locus_tag="PB779_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0739468.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            4661..5938
                     /locus_tag="PB779_001948"
     CDS             4661..5938
                     /locus_tag="PB779_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HDE0739469.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            6001..8703
                     /locus_tag="PB779_001949"
     CDS             6001..8703
                     /locus_tag="PB779_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDE0739470.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            8855..9172
                     /locus_tag="PB779_001950"
     CDS             8855..9172
                     /locus_tag="PB779_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739471.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            9202..9522
                     /locus_tag="PB779_001951"
     CDS             9202..9522
                     /locus_tag="PB779_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDE0739472.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            9630..11090
                     /locus_tag="PB779_001952"
     CDS             9630..11090
                     /locus_tag="PB779_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739473.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGILPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGSNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            11158..11379
                     /locus_tag="PB779_001953"
     CDS             11158..11379
                     /locus_tag="PB779_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739474.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            11410..11592
                     /locus_tag="PB779_001954"
     CDS             11410..11592
                     /locus_tag="PB779_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HDE0739475.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            11592..12005
                     /locus_tag="PB779_001955"
     CDS             11592..12005
                     /locus_tag="PB779_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HDE0739476.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            12128..13309
                     /locus_tag="PB779_001956"
     CDS             12128..13309
                     /locus_tag="PB779_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739477.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(13380..13544)
                     /locus_tag="PB779_001957"
     CDS             complement(13380..13544)
                     /locus_tag="PB779_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739478.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            13698..13771
                     /locus_tag="PB779_001958"
     tRNA            13698..13771
                     /locus_tag="PB779_001958"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:13732..13734,aa:Arg,seq:cct)
     gene            complement(13840..14979)
                     /locus_tag="PB779_001959"
     CDS             complement(13840..14979)
                     /locus_tag="PB779_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0739479.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(15278..15913)
                     /locus_tag="PB779_001960"
     CDS             complement(15278..15913)
                     /locus_tag="PB779_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739480.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINNASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(16026..16661)
                     /locus_tag="PB779_001961"
     CDS             complement(16026..16661)
                     /locus_tag="PB779_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HDE0739481.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(16695..17156)
                     /locus_tag="PB779_001962"
     CDS             complement(16695..17156)
                     /locus_tag="PB779_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HDE0739482.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(17286..17717)
                     /locus_tag="PB779_001963"
     CDS             complement(17286..17717)
                     /locus_tag="PB779_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDE0739483.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(17735..18055)
                     /locus_tag="PB779_001964"
     CDS             complement(17735..18055)
                     /locus_tag="PB779_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0739484.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            18354..19130
                     /locus_tag="PB779_001965"
     CDS             18354..19130
                     /locus_tag="PB779_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HDE0739485.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            19145..19348
                     /locus_tag="PB779_001966"
     CDS             19145..19348
                     /locus_tag="PB779_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739486.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            19364..19702
                     /locus_tag="PB779_001967"
     CDS             19364..19702
                     /locus_tag="PB779_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HDE0739487.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
BASE COUNT         6332 a         3383 c         3774 g         6261 t
ORIGIN      
        1 ttctttgtca cacccccttt tgttatcaat cgtttaattt tccacgttca cgataccagt
       61 tatctggttg ccagatccat tcgaatccgt ctttttcaag tagttcgaaa gctgctttag
      121 gtcccattga tccagctttg tagttgggaa aatccggttg tgtttggtcc caagcttttc
      181 gaatgacatc cacgatatgc caagattgag cgacttcttc ccaatgagag aagttcgttc
      241 catcaccatt caacgcatct aatagtaatt tttcgtaagc ttctgggcta ttttcaacca
      301 tttctgcact atttctaaat tccaatttga ttggttccgt ttcaaatcct tgccctactt
      361 ctttcccatt caaggataaa gaaaatcctt cagttggctg aatatagatc gttagaacat
      421 taggtggaag tgtcgtatcg tcacatggtt catcgacaga tgttttgaat acattaacag
      481 gaacttgttt gaatacgatg ttgatccgag tccctttttc agtcaaacgt ttgcctgtac
      541 gtacatagaa aggaacacct gaccaacgga agttatcgat agtgaatttg cctgcgacga
      601 atgtttcagt ctctgattga gcatccactt tgtcttcttc gcgatagccc ttgaattgta
      661 caccatccaa ttcaccttga gcatattgcc cgcgaacgaa gttttctaac acttcttctt
      721 cgttataaat gcggatagct ttcaatgctt tgatcttttc tgtacggatt tctttttcgg
      781 aaaatgctac tggcggttcc attgcaagta atgctacaac ctgtaaaata tgattttgca
      841 ccatgtcttt aagtgcgcca ctatgatcgt agtagccccc gcgatcttct acaccgaggt
      901 tttcgccaaa agtaatttgg atattgtcga tatagcgatt gttccattga gcctcaaaaa
      961 tattattggc aaaacggata gctgagatgt tttggatcat ttcttttcct aaataatgat
     1021 caatcctgaa aatatcttgt tctgggaata cttctctgat ttgctggttc aattcaaaag
     1081 cagactggta atcagaaccg aacggttttt ctatgatcaa acgattgaag ccattttttg
     1141 tcataatatt ttgtgatttc aaatgagaaa cgatcgttcc aaaaaattga ggtgccatag
     1201 ccaaataata gacacggtta ccgtttaatt gatagtgtcc atctaatcgg tcagacaatt
     1261 cttttaatgt ctgataatgc gttgaatcat ttacatcatg ggattgatag taaaaatggc
     1321 ttgcaaaggt agttgcttct tcatctgaag gattcaatgc acggattgtt tctttgacaa
     1381 cttcacggta gtgctcatcg ctccagggac ggcgagcggt tccgattaca gcaaaatgct
     1441 cgcctaaatt tccttttctg taaaggcgga acaaagacgg gtacaattta cgctgggcta
     1501 ggtcacctgt accgccgaat atcgtaaaca atacattttt ttcattagac atgtggatac
     1561 actcctttat attttatcga caaaaatcgt gctggccgcc ttaaagctga cggggatttt
     1621 ctttctatca ttttggatag tgatcggtcc ttcataagct gcgatgtcaa cgatctcata
     1681 ttcttcgttg atattcaggt caatagtgac taagtaatcc aacaattctt tttcatcaag
     1741 cactcgtgcg atacgcactt ttgtaccgac aggataggac tccaatgttt gtcggcgttc
     1801 ttcatggaca acttcctctt ttttaggaat cgatcctcca tgaggacaat gttcaggatg
     1861 attcaaatag ttttctaaat gatctgcaag atgttccgaa gtcacatgtt ccaatacttc
     1921 agcatcatca tggacttcat tccagctata gtctaaatgt tcaactaaaa aaacttccca
     1981 taagcgatgt ttgcgaatca gactgctagc tttttgcagt ccgcttgcag tcaattgtac
     2041 accttgataa ggggaatgtt ctacaagctc ttctttcaca agtttagaaa tcatttcact
     2101 gacagatgca gctgagacat ctagactaga tacgatttgt ttattgttga ctttcgttgt
     2161 atctccacct agttctaaaa tgattttcaa ataatcttct cgatttggtg tcatattcga
     2221 tcatcctttc atggtaaaaa accatcatta gtaagtgtaa caaaaaaaac gttaattgac
     2281 tatttttcta aataaaaaac aaaggatttt tagacgtttt tacaacaaaa aacgaaagat
     2341 gatagagaag actcattctt tcgtttataa aggatatata tatacattgg gagggatcta
     2401 tttttcagat aacaacttat atgaagtgtc tgcagattcg tcataaagag tttgttcggg
     2461 ataagaaaag ataagataaa aaccatactg atcacgtacg actaaacgat attcatctat
     2521 ttctaccaca gatgtgccaa gagactgacc gttgatcaaa aacgtgtaat cagatgtaat
     2581 ctgtaattgt tgtttttgct ggctatcact aaagaaccat gtaccttgat actttgagag
     2641 tccttctgac ttttccgctt gttttttctt tttcaagtaa ataaaacttg agagaacggt
     2701 aatgagtgaa ccaagaaaat agatcatttt ttttatcacc aaatcactcc tttatgagaa
     2761 aataatcgca tagacatatt ctttcttctt tatttcattg taccgaataa aagctaaaat
     2821 ttctctaaga ctttcgactg gtttttttac tgtttttcta caaattatga taggatacat
     2881 agtaggaaga aaggtgacat aatttgaagt atcagcaagt ggaaatagct ttttttattg
     2941 accgcccgaa tcggtttata gcacattgta tgaaaaaaga cggagaaata attattgcgc
     3001 atgtcaaaaa tacaggtaga ggaaaagagg tcctgatacc aggcgctgaa gtggctattg
     3061 tatttgctcc tggacctaaa cggaaaaccg cctatgatct gattgctgta aaaaagaagg
     3121 gtgactggtt taatatcgat agtcaattgc ctaatcggct ggcaattgat ggtattttag
     3181 acggcacgat ccttttacca ggattaactg gtccatttac ggtatacaag cgtgaagtaa
     3241 cttatcttca ctccaaattt gatatttatt tagagacggt ggtcggacaa aaagcatttg
     3301 ttgaagtcaa aggtatgaca cttgaaaata aagcgattgg tgcttttcct gatgcgccca
     3361 cactcagagg attgaaacat ataggagaat taacgtatgc cgcacaagat ggttatgccg
     3421 cttatgtctt gtttattgct cagttcgaac atcttcatct ggcaacgatc catgaagaaa
     3481 tgcaaccagc actagctgat atggttcgac atgcgcagca aagcggagtt caaatcctcg
     3541 cctataattg tcaagtatcg gcagatgagg taactgtcaa gcaggccatt ccatttgatg
     3601 tagatatccc ttttgaagat cctatacaat agaaagaagg taaaataatg atcaacttag
     3661 gtattatcgg aacaaattgg attactcatc aatttgtcca agcagcttta agcacaaaaa
     3721 aatatgaatt gacagcggta tattctagac atttggaaaa agcacaggaa tttggttctc
     3781 attatgaagg ggatatcgaa ttcgcaacag atttgaagac ttttttcaat attactcata
     3841 tggacaccat ttatattgct tctccgaata gtcttcactt tagtcaagct aagcaagcaa
     3901 ttttggcagg aaaaaatgtg atagttgaaa agccagcttt ttcgacgcca aaagaaatgg
     3961 atgaaatcat ccatttggca aatgaacaca atgtgtattt ttttgaagca gcaagaaata
     4021 tccatgaatc aggttttaaa aagattgccg attacttacc attaaaagac gagataatcg
     4081 gtgcaaattt cagctatatg aaatattctt cgcgctatga ccaagtatta gatggagaag
     4141 aaccgaatat cttctcgact catttctcag gtggtgcatt gatggattta ggtgtttacc
     4201 ttgtatatgc agctgttgct tggtttggaa tgccaaaaga agtccattat ttcccaagaa
     4261 agatttctac tggtgtagat ggtcttggat gggggatctt acgttatgag aattttgatg
     4321 tatcgatcca gccaggtaaa atcggtgatt cttatttacc gtcagagatt tattttgact
     4381 caggaacgct agtgatgaat ggagtcaatg caattgaaca agcacaattt catgatcgcg
     4441 cgcataaaga aatcattgat ttggcggtaa cagctgcaga aaatccaatg gcagatgaag
     4501 cagaggattt tgccaatgtc atggctcatc cgaaagatcc agcttgggga ttgttgtatg
     4561 aagagtggat cgagctagct agaaatgtga accaagtgat ttatgattta agaaaaaatg
     4621 gcggcatcaa attcgatgca gataatgagg aagattttta atgaacgaat ttgtacaagt
     4681 atttcccgaa aattggcaga aaaaatatga ggataaaggg tttatctcac cttctcttat
     4741 tcaacgagca gtttttcagc cactaagtaa taaacaaagt atagtagcgg tttctcctac
     4801 aggttcaggt aaaacactgg cttatctttg gcctctacta ctaaacgtgg aaccaggtga
     4861 agcaagtgcg ttggtcattt ttgcttcttc tcaagaacta gctattcaag tagcagatgt
     4921 tgcacgtgaa tggggaaaag acaaagagtt gaaagtccaa tctttggtgg gcggagccaa
     4981 cgtcaaacgt cagattgagg gtttgaagga aaaaccagaa atcttgattg gtacaccagg
     5041 aagaatattg gaattgatga aagcaaaaaa aataaaagca catcaagtga aaacaatggt
     5101 atttgatgaa gcagaccagc tatttgacgc tgggaacagc caaatcattg atcaaattct
     5161 tcatcaagct ccaacagagt atcagctagc ttttttttca gcgacagcag atcgttccct
     5221 tgaaagcatt gaaaaaatca ctgggaaaac gtttgagaca attgacgtga cagcagagga
     5281 cgattctcga aaaggactga gacattactt tttacgtgta ccgatacgaa agaaagatga
     5341 ctacttgaga cgtctcacgc atatagaaga ttttcatggt ctgattttct ttaatcaact
     5401 gactgaatta ggcgtaatgg aagaaaaatt gctgtataga ggtgtaccgg taggaagtct
     5461 ggcctctgat cagaacaagc tactccgaaa agcagcgcta gaacaattca aaaagaaaat
     5521 ggtcagagca cttttgacca cagatgtggc ggctagaggt ttagatatta caggtcttcc
     5581 ttatgtagtg aatgcagaag ttccgttaag tgaagaagct tatttgcatc gttcgggaag
     5641 aactggtcga atgggtaatg aaggaatagt aattacactc gtacaagata ataatctaag
     5701 agatttaaaa cggcttttac gtccatcaaa tataacactt gaagagattt ttttatacgg
     5761 aggtaagctg caaactgagc agccaaccaa agaagatgca gctcctgcag taaataaaaa
     5821 gtatgcgaaa actttttctg gaaaggagca gaacccagaa tataacaaag aaaaaataag
     5881 aaaaaaagtt aaaaataaat caaaaaaaga gagaaataaa ggagcaaggc gcaaataagc
     5941 gcctttttat gctatgatta tgaaaacggg aacaaaattg gttgccagag gaggggttat
     6001 gtgaaagaac gtcaagaaga gatcttgcag ctattgacag aaaaccaaca aggattgaca
     6061 gcaagtgatg tagctgagcg cttaactatc gatcgaagca atgcaagccg atatttaagt
     6121 gaactataca aggcccatca tattgtaaaa accgctggcc gaccagtcgt ttactctttg
     6181 ccaacggaaa agtcaaaatc tgatgaagtg catgtcgact cttctacgca agtgactttt
     6241 gaaacactcg ttggagaaaa tgattcttta aaagtcagca tacagcaggc aaaagctgcg
     6301 attctttatc caccgcgggg gttgcatacg attatttttg gagaaactgg tacagggaag
     6361 tcgatgtttg ctgaatgtat gtatcatttt gcaatcgatt cagagatgct ttctgcagat
     6421 gcgccatttg tttctttcaa ttgtgcggat tatgctcaaa atccgcaact gctctttgga
     6481 cacatctttg ggatcaaaaa aggggcttac acaggagcag ctcaagatag tcccggtcta
     6541 atagccaaag cagacggcgg tatattgttt ttagatgaga tccaccgttt accgccggaa
     6601 gggcaggaaa tgctgtttac tttcattgat aaaggtattt accgtccgct tggagaaagt
     6661 gcacaagtac atgaagcatc tgttcagatc attggggcga cgactgaatc ttcagaaagt
     6721 ttcttatcta cgttcaatcg acggattcct atggcaatca ccttgccgaa tcttgcttca
     6781 cgttcactgg atgagcgtta tgaaatcatc tctcttttta tcaaacaaga agcgaatcgt
     6841 ttgaatcaac gtatcgatat cgaaaaagaa gcgattcttg ccttcatgct ttatgatgcg
     6901 gaaggaaata tcggtcaagt gaaacgagac ttgaaactag tctgtgcaaa atctttttta
     6961 cattaccgta ctcatcatga gaaaaagcta atcattcgaa aagaagaact ttcccttcaa
     7021 gtacaaaaag gattactgaa aatcaaggaa ataccggaac gtctcgaccg attcatggac
     7081 agcaaaagtc agtatttgac atttgaacca ggatttgctg atgttgtctg gtcacaagat
     7141 ccagaacgaa acatgcaggt ctataacgat attgaggaaa aagtcacttc tctttccgaa
     7201 accggtgtgg agaacattga tctagagacc ctcatttcaa aagatgtgga tgcttatttc
     7261 cagacatatg tcaaagaatt gactaaaagt tcgattccca aagatctttt gccagatgaa
     7321 atctggcggt taaccaatca attgtatgat gtggctgaaa aacggttaga ccgtatttat
     7381 aatgaaaaag ctcgttttgc ttttgctttg catctgcaaa gtacattgga tcgtgtgaga
     7441 gaaggtcata tgatcgtcca cccagatttg aataacgtac ggaaaaattt taagagggaa
     7501 ttccaggtag caatcgatct ttcaacgatc attgaagaag aagaacaagt tgagattcct
     7561 tttgatgaaa tcggctttat tagtatgttt ctttctatca atctaggaga aagtgagcct
     7621 gttaaagaaa acaaagtaga tgttctcata ttgatgcacg gcagacagac tgcttcaagc
     7681 atgttggaga tggcacaaga actattagga acaaaagtag ggaaagcttt taatatgcca
     7741 ctggttatgg aagttcaaac aatgtatgaa gaagtgttac aatatgtcaa aaactatcaa
     7801 gagcatttga cgaatggcct actcttgtta acagatatgg gatcattaaa caccttcagt
     7861 gatttgattt atgaagagac tggcattcgg acgaaagcta tcacgatgac aagtaccatg
     7921 attgtgatag aagcgatacg gatggcaagt gttggaagaa gcttagaaga tatttatcaa
     7981 aatatccagc tttcctttga atcgatcgta cgtgatcagt tcaaagcgga aaagtctgaa
     8041 actttacagc gtaaaaaagc cgtaatcgtg acatgcttta ctggtgaagg agtagctgcc
     8101 aaattatatc agcgtattat gccagtgatt aatcaaaata aggtagaact gatccagatg
     8161 cagtttttag aacgtgaatc attcaaaaaa cacatcgatg ccttattgga agaatatgag
     8221 atcaaagcaa ttgcgggaac agttgatgtt gattatcaaa atatcccatt tttttcagcc
     8281 tatgacgttt ttgatgatga aaaactaaat attttaaagc gtatagctga tgatgagatc
     8341 ccgacagcta aaattgtcga ttcacttgct ggatcattaa gcgatgtctt ttctattgat
     8401 gaactgatcc gttcattgca aaagacagtt cagcagatcc agaccgattt gtcgattatc
     8461 gtggaacctg gagtagatac tggaatcgtt atccatttag ccttcatgtt agacggattg
     8521 atcaaacaag aaagccatcg gcaatttgag aaactgtcta ttttctcaaa aatttatcgt
     8581 ttggaaatgg atatcgttcg ggcaaacttg atggcactag aacgaaaata tcaggtaaaa
     8641 attccagaag atgatatcgc atttcttaca caaatgtttc ttgaaaataa aataaaaaaa
     8701 tgaacacact aatcatactg tttacacact aaacatctgt gtgcgcacta taaaaaagag
     8761 ctaaaaagca tgaaaacgct atttcagctc ttttttttat tggcatgctt cttgcgttat
     8821 ataaaagtgt aaaaaaataa aaggagtgtt aaaaatggca aaaaaaacaa tcatgttagt
     8881 ttgttcagca gggatgagta cgagtttatt ggtcacaaaa atgcaaaaag cagcagaaga
     8941 aaaagggatg gaagccgata tttttgcggt ctctgcctca gatgcagata ataatttaga
     9001 atctaagaat gtcgatgtat tattattagg tcctcaagta cgtttcatga aagctcaatt
     9061 tgaacaaaaa cttgcgccta aaggtattcc attagatgtc atcaatatgc aagactatgg
     9121 catgatgaac ggagaaaaag ttcttgcaca agcagaaaat ctaatgaaat aaatcaagta
     9181 tgcagttggg ggtataacaa cgtggaagat caacaaaatc tagaagccat catggggtta
     9241 atcatgtttg gcggtaatgc aaagagcgat gcaatggaag cgattgcggc tgctaaaatc
     9301 ggtgattttg agttagcgga taggaaaatc gctgatgcag aagaatcact tatacaagcg
     9361 catcatgcac aaacagacat gttgacacaa gaagcacaag gaaatcatat gcaagtgaca
     9421 ttattgactg ttcacagtca agatcactta atgacatcta ttgcgtttac tgatttagca
     9481 aaagaaatca tcgaacttta tcgtcgcgta tacagcgaat aaatacaact tcttttttga
     9541 acggaagaag aaaaattttt gaacggattt tttattttgt tataaggaga actctcttta
     9601 tataaaaaac ttataggagg aagtaaaaaa tgaacggact atcaagttgg atggagaaat
     9661 acatcctgcc ggttgccgca aaaatcggag cgcaaaaaca tttagttgct ttgcgtgatg
     9721 cttttatcgg catactgccc gcaacaatgg cgggatcagt cgctgtaatg atcaatgcaa
     9781 ttattcgtga tttaccgcaa cagtttaaca gtacctatgc tgacagttta gcagcagaca
     9841 aaggaatctt tgccgtattg aatgtcatca tcggaatcaa tggttttgtc tggaacggta
     9901 cactagcaat cgccggattg atctttgcct tttcttgggg gtataatctt gcccgagctt
     9961 atggagtaaa tgatctagct ggggggatcg ttggtttagc taccttgatt caaggtattt
    10021 cctttggtcc agcattatca gcagcattag atgtgaatgt tccttcaaat gtcgcagatg
    10081 caatcaatag ttctgagatt ggtgcaacga ttgcagatgg cacactgtca gttggattat
    10141 ggggttggct aaaactagat catttgaatg gaaacgctta ttttacagtt atgatcatgg
    10201 gagctatttc agtcattatt ttttgtaaat tgatgcttgc caacattacg atcaaaatgc
    10261 ctgattcagt accaccagca gtatctaaag catttgcagc cattttacca gcgacgatcg
    10321 ctttatacgt cattgctatt atcaattata tcgtaggtcg tgtagctgat gggcaactga
    10381 tcattgattt ggtgcaaaaa tatattgcag aaccattcct aggattatct caagggttgg
    10441 gagcagtatt gatcgtcaca gtatttgttc aagtattctg gttctttggt attcatggat
    10501 caaatgtatt ggcaccagtg ctagagggaa tctggggaca agcacaacta atcaatattg
    10561 atattttcca aaaaggttat aacggaaaaa ctggtacacc agccgtgtta gatgcaatcg
    10621 aagatggaaa agcttatatg tgggtccgcg gatcgttcga tgcttttgca tggtttggcg
    10681 gatcaggcgg aacgatcgtc ttactgatag ctatcttgat tttctctaaa cgtgcagatt
    10741 atctaacagt agctaaatta tccattgggc ctggtatctt caatatcaac gaaccagtga
    10801 tgtttggtct gccaatcgta ttgaatgcaa tcatgtttat cccattcttg attgctccag
    10861 tagtagcaac agcaattgga tggacagcta cttatcttgg cctagtcgct ccggtatcgc
    10921 agcaagtcac atgggtagta ccgccgttct tattgtcatt cttagcaaca ggagcggatt
    10981 ggcgggcacc gatcgtaaca ttagtatgta tggtcgtgac tttcttgatt tgggcaccat
    11041 ttgtcatctc tgcaaacaaa atggaccctg ccgcaggcga acaacaataa gatgaacgtg
    11101 aggagcggga cgctttaagt ttcgttcctc ataatgaatt ttcgaggagg aactgaaatg
    11161 attacaattg ccagtgcaat gcaacaagat gaaatcaaag aattgttaga aggatacaat
    11221 gaagaaggaa tgacttttac atttaaagaa aaacaaggaa tcaagctgtt ctttgaaaca
    11281 agtgcagaag atccggaagt tgcggctaaa aaagcaaagg aactaatcaa agcacagcct
    11341 tggggaacag tcctttattt tcaatcaaca gctgtttaga aaatggttta aaaagatagg
    11401 atggttgaga tgataaaaaa cggtttattt ttatgtagta ttggttcttt gatcgtgttg
    11461 tatagtttga atccacattc gcaaaggtat gatttgtata gtatggtcac aggtcttttt
    11521 ctaacaggat taggaatcta tttcttcatg aaggggaaaa aaagagaaga agcaaaggag
    11581 aaaaataact aatggaaatc acgaaaaaat taaatattcc agcatcgttt ttttacgata
    11641 aagttatgga ctctgtcctt ttcgatgtac gtaaagcgac cggcaaatca gtaactagaa
    11701 aacagctgaa aaatttggag tacgtcaaac aattctcgca aaataaccgg gctcgcataa
    11761 aaatcgaaga agtcattgaa aaccagtctt ataagtttcg tacatcgaca acgaagaatg
    11821 aattcgtcgt tcattatcaa atcaaaccat tggacgattc gacctgtgag gttcattaca
    11881 cagaaaaaat ggagtcttat ggcatgcttc aaaagttgaa tgatatgctt ttaggaacaa
    11941 tcttgatgta ttttaaacgg agacgtttca aaaaaatgct agatatgatc gaagcaacgt
    12001 attaaatcaa tgaaacatgg tactatttag ttattgaaaa atgaagtaag ctagaaggaa
    12061 tttttcatag gaagatagat ctttcctgcg aatcctcact agcttttttg taggaagggg
    12121 cagcaaaatg acaaacaaag taagagagct aggtgtatct tcgattgagg aaatgtttga
    12181 tttagccact tatgcattta atggggcaga tacacctgaa aggcgagaac gttttcgtac
    12241 acttgcggag aattcttgga attacggatt ttttgatgag gaggatcggc taacaagtca
    12301 agtcatggcg accccttttc cagtgaattt ttacggacaa gagtacctaa tggccggcat
    12361 tggctatgtt gcttcttatc cagaagcaag gggacaaggc gggatcaatc agatcatgga
    12421 aaagatcctt gaagattgcc gtgatcgtaa agtaagctta tcttatctgg cgccattctc
    12481 ctatcccttc tatcggcgct atggctatga acaatcattt gataaaatca gttatcaact
    12541 aaacagtcgt gatgtgccgt ttatcaaaaa aaaatctgga aaaataaagc gtatggattt
    12601 tgaagatgca aaagctgcaa tcagaagaat ttatgaacag atgccggaaa accaacgagc
    12661 tggtctgaag cgcgaagact ggtggtatac gtataaattc aagcaaaaag gcaattacca
    12721 gtttgctttg cattttgatg ataatgagga agcaacggga tatatcgttt atcagcttgc
    12781 aacgtcttcc tttattattg cggagtgggg atttttggat catgatgctt tttgcagcct
    12841 tgttcgcttc gtaagttctc acaatggtgc ttttgaaaca tttgaatatt catgcggcta
    12901 cggcggtaat gatcaaaatt atctattaga aaatccattt gcttctgtaa tgatcacacc
    12961 ttatatgatg gcgaggatcg tagatatttc tttgtttttg gaaaattatc catttaaaaa
    13021 gagacaagct gcatttgccc tacaaataga agaagatcat tatgcgaaat ggaatgaagg
    13081 aatcgtggaa gtaacaatcg aaaatggaaa aaatcatctc tcaaaagtag aacaaacaaa
    13141 actcccaatc gttcgaggaa gtatccaaca tatcacgcag ctattattag ggtatcgtaa
    13201 agtggaagag ttggtattcc aagaaagaat acaggtgaca aaagaatatg aagaaacgtt
    13261 aagctcaatc ttgccacagc aacagccaat tcttaatgac tatttttgat aaaaaacggg
    13321 tgatgacaat atttttgtca ccaccctttt gtttttcatt tggcatttga aggaaaatgt
    13381 taaagtaaat cctctttttt cgtaaatttg aattttttgt tttcttttgt tttagggttt
    13441 tcttttttgt ggtcttggat tgcttctttc gtaatctttt cccgattttt tttagatgaa
    13501 tctaagcgtt ctgcgtatac tttttctttt ggcttatcat tcattggaaa ggacctccct
    13561 acattatttc attctacctc tagtttatca tctgttaagg actagtggaa acgttttgcc
    13621 taacttataa gctgattttt ttagcagata agcttgcaag taaaaaacaa acaagctaca
    13681 attgatttat tgaaattgtt cctgtagctc agtaggatag agcaatcgcc tcctaagcga
    13741 taggtcgctg gttcaattcc agtcaggaac gtataaataa cccctgtatc ctttgcggta
    13801 caggggtttg ttttgtattt gtgccaaaaa tgtgccaaac tagttatcat ttttatataa
    13861 actatcgaac acagtattga ttttttcttt atcctgatct tcaagctctc gaacaatatg
    13921 aagataagta gacattgtag tttctaaact gctatgtcct aaacgtttcg atacgctaag
    13981 tatatttact ccttgataaa gtaaaataga tgcatgtgta tgccttagtc catgcaaagt
    14041 aaattgcttt tcaatcccta attcttttaa ttttttgcgc aaatatttgc tgacggcgtt
    14101 tgatgaaact aatccatttt ttaagttgaa aaaaacaaaa ttatgagggt ttttgatttc
    14161 aaaattctcg aataattctt tttgattgat tttaaacttt tttaagagat caatcgtatg
    14221 tttatcaatg gaaattttcc tatttgaagt ttcgtttttt gtttttcccc attcatttaa
    14281 tttataattc catgttttat taatagtgat gatttgatct tcgaaatcga tatcttccca
    14341 tgttaatcct agaagttcag caaatcgcat tccagtggca ccagcaacta acacgagcat
    14401 aggagaagag tactgcgcag aaaggttttc ttctacgagt ttcattaaag atttaaattg
    14461 atcataatct aaatatttat cttcttttgg cttcaatgaa tcttttcctt tgattactgc
    14521 ttttctagtt ggatcaaacg gaattaatcc ttcttctacg gcatctttca acgacgctct
    14581 aatatggtta ttaaacttaa taacggtaga ttttacatgg tctttagcat acttatttaa
    14641 aaagcgttga tatcccactc tatctaaatc agaaatcaat accgctggca tatatttctt
    14701 tatgttcatt aacgtatctt cgtattttct ataagtgata ggagatactg ttccttcttt
    14761 ataaagttgc atccaatcct caaagtaatc tgataataat agatttttgc gatccccttt
    14821 aaggcctttg ttcaagttat attctaattc gttggcggca tcttttgctt ctccttttgt
    14881 cttaaatcct gattttctta tcttcgtgta ttttccgtca tcttttttgt atgaaatttc
    14941 gtattgccaa ctatttccac gtttgactaa tcttgccata attgaatcag ctctctttct
    15001 ctgatacaat aggaactata aagaagccca ttgtttgggt tttattattt tttgcacatc
    15061 ctttttgctt gccggcgcaa ggatgtgcta tttgtcgttt taatggtata attggatgtg
    15121 tattagatca tccaatcaga ggtgtttatt atgattaaag tgatttttaa aagaataact
    15181 gaacttccag agtttagatt atttgttgat tattggtatg tctggttttt tattgttgca
    15241 ttgctgatag gtctagatgt catattagaa agaaaactta agtaagagtt gagttaataa
    15301 attgaattcc taaatgagat attttgtagc ccatattttg tttgccgaca tcacctaata
    15361 ctatggagct aatcgttttt tctaacagac caaaatcaga taatctattt aagctaccat
    15421 ctattagctc ttgtgaatag ccagacatgc tgatatttcc agtgaaattt tcgtttccac
    15481 gactcattaa gcatgctaac aattgaatct caatcgatgt taattgattc agtacaagaa
    15541 gataatactc ctcgttatcc catgaagcgt tgttaattcg aagtaaacaa ttcttataaa
    15601 gatttttata catatctatt ttattttgtg cctttgattt ttctacctcg tcatttatcc
    15661 cttcgaatat tccaatgagt tggtccttgt tctctaagtt gaaaacatct tctggaattt
    15721 gatcgcgaat gttttctaat gattcgttta aatttttgta gaatttctcg atgcgtttga
    15781 aacgcttctc gtttttagac ccaaaataaa gtgactgcac aacgccacca atataaggaa
    15841 ttgctccaat accgccttca actattaatt caagatattc ttttttggtt agtttttcat
    15901 tgctattatc catagttacc tcctattttg tcatttcctt tacaagcatt gtgactcctg
    15961 atggcactct tttgtatagg ttttattatt gtgcacaatc taactcttag tggggcgtgg
    16021 ttcatttatt ttttacttac tttactatta atcatatccc attgagcata ggatttttct
    16081 atgttcgatc ctcttgaact aatttctcct gtaaaagtta ctttatcgcc ctttgtaaag
    16141 gtatcagcat tgtttaagtc cttcgcaaaa attacatatg aaactttagg tgttgcagaa
    16201 atatcattcc aacttttatc atcgtactct ttgtctgcta taatggctat tctagtagtc
    16261 attgattcga taacagttcc ttcaaaagta tatgttttac cactaatata tttagtaaaa
    16321 gctgtatttt gctcagtagc tggagtaata gaataataac tatctaagaa agcaccccag
    16381 tcatgattat ttgtctctaa aaattcttca aattgagtta ggcttttatt gctgctgtta
    16441 gatgtagtag tttgagtatc agatgatgag ctttcctgtt tgttattgtc atttgcctcg
    16501 tttgatgagg aaagcgagaa acctacggta gtaaaaataa tcccgataat aaggagaatc
    16561 ataggtgttt tcttatttgt ttttttgata aatcttacaa ttaacatgat taaacctata
    16621 ataaataaaa caataccagt aaaaccaaat ataccgtcca ttaatagatc ctctttctct
    16681 tttgatattg aatattataa accaagcaat tcttttttct taaaatcgaa ttcttcttga
    16741 ttaataatcc cttcatctaa caactcttta tactttttaa tttcatctgc acttgaaatt
    16801 tgtgtttctt tggaattatt atctaatata gattgttgct tctctatata tttttttaaa
    16861 ttttccattt cattccaata tttttttgta aacataacgg tgttttcatc tttcgtggcc
    16921 gctaatatac ctccgcgact ttcgtttccg cctagcaagg taaattgtat ataaccatta
    16981 ctcatacctg gtttttttaa ttgtacggct gatatatttt taaaggggat agttttttct
    17041 cctttaatac cttgattaac taaatttata aatccttttc taataattga aatagaatca
    17101 tcagttactt taatcaaggt ttttcctgga gattttatta aaatctcttt ttccattttt
    17161 tcttcctcat ttctgtgata tgattttttt tgtagaagct catatatgag gaaagagccc
    17221 gtgttgcagc acgggctttt ttaatgtttt gctgaaatcg gtttttttaa taattcttga
    17281 tgtattcata catattgcct tgcgtaagaa tattttttct taaaatagca ttggcagaca
    17341 gcataacaag tgtatctgag cttattctga atagaataat actccataaa tttttcgaga
    17401 ttaaactgag attcatcagt cagttcgttc tcaatataga tatttaataa aattagaata
    17461 gctattttat ctgcttctgt ttcaaatttt gagtgaaaag ttgtagaagt atcgtacaaa
    17521 actgaaaatt caaaatgaga ggcgctgaaa tgtgcaagtt catgagataa atgaaaggct
    17581 tctgcagttt caccgtatag attttcattc aaaaaaatga ttctgggttt tggatagtag
    17641 aaaccaggct ctttcatctc catataaact actttcaaat tgtattcgct caacatttct
    17701 ttcaatttca aatacataca aaccatcact ccaactattc attttcctct aaagctttag
    17761 caattgcaat cgctttacgc attgtctcct tagatatttc ttttccatca aaagaaaaaa
    17821 cagtatcgtc ttctgataaa tccacatgtt taggggtttc tctttcttct ctacctagaa
    17881 ggtagtctac agagacatcg aaatagtcag caatccgact taattcatct gaattaggag
    17941 tattattttt ccactttgct agataaccgt tagaatatcc aaaattaatt tctaactgcc
    18001 gtatagatat ctttttcctc ttcgccaagt cttttattat ttcataggta ttcatcgata
    18061 aaacaacctt tctaaatgtt tacaaaaaaa gtttagaaaa atacgcagaa ataatttgac
    18121 taattctgag taatgagcta tactatatct tgtaaacaga tttaacaact aaaaagacaa
    18181 caaaaaacac tattgatatg taaatgcaga ccgccaagaa agctttaaaa tcaatgtttt
    18241 tatgtcttat ttaattatgc tcttagtata gagtattact cagatactgt caattgaatt
    18301 tagaaaaaag ttgttaaatt tgtttacgaa tataaaagaa aggaatgaga aatatgaaca
    18361 caccgcaaat ttttaatttc gaacaaaacg aagttcggac aattttagta aatgatgaac
    18421 catattttgt aggcaaagac gttgcgagtg ttttgggtta ttcaaacact aaagatgctt
    18481 tgtcgcggca tgtagatttg gaagataaga tggggtcgcg aatcacgacc tcaggtcaat
    18541 caagagagat gacaatcatc aacgaatctg gtttgtacag tttaatctta aaatcaaaac
    18601 ttccctctgc caaaaaattt aaacgttggg taacaagtga agtgttgcca gcaattagaa
    18661 aacatggagg ttatctaact ccagaaaaag tagaagaagc tttgcttaat ccagatacaa
    18721 tcattcaatt agcaactcaa ctaaaagaag aaagaactgg aagattaatc gcagaacaaa
    18781 agattgcaga gtacgaacct aaaatctcct atttagatag catattatct tctacagatt
    18841 cagtaacaat tagtcagatt gcagcagatt atgggatgtc tccacaacag atgaataaat
    18901 tacttcataa actaggtatt cagaaaaaag tcggtaacca atggttattg tgcaaaaaac
    18961 acatgaacca aggatacaca aaatctcata caactgagat cccgaaagcc gatggtggca
    19021 ctaaaattgt aatgaatacc aaatggacac agaaagggcg tctatttatc tacgaattac
    19081 taaaaaaaga aggatattac cctcaaatgg atttagagga aattggttag aaaggagttt
    19141 tagtatgact gacattgcag aaatcactca acgagataga gaaaaaatca aagaatatgt
    19201 cgaaagttca aagttcttaa cttacaccat gcttgctgaa agatttggaa ttagcaaaag
    19261 ctacttatct ttaattttaa acggtaaaaa gacttctgca gaagcaaaca gaattataga
    19321 ttcgattatc actatgtacg aattgtaaag ggaggaacag ctaatgcaat atctagaagc
    19381 aaaaatccca attccagaag gctatgtaat tatctcccaa gtggattatg aggagttaaa
    19441 aaaagctgat gatactggta gatggatgac gttgccagaa gtgctagaac ggattaacag
    19501 aaaatatgat tggtttactt ctagagtttt aaagaaccca agatatagaa atattatcga
    19561 tatcgagaaa aacaaaaatg gatttgtcta ttatccagtt gaaggaagag acacatatct
    19621 atttttaaga agtaaaacac ttgaattttt agaaacaaat ttttcggaaa tcttaaggag
    19681 gcaagcggat gggaaaattt aatagagcgc tagtgttcag cgcaccgcta atcatctacg
    19741 ctttaggact
//
LOCUS       DAMEEU010000055        19507 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.056, whole genome shotgun sequence.
ACCESSION   DAMEEU010000055 DAMEEU010000000
VERSION     DAMEEU010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 19507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19507
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.056"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(460..1089)
                     /gene="udk"
                     /locus_tag="PB779_001968"
     CDS             complement(460..1089)
                     /gene="udk"
                     /locus_tag="PB779_001968"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HDE0739488.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1173..1868)
                     /locus_tag="PB779_001969"
     CDS             complement(1173..1868)
                     /locus_tag="PB779_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HDE0739489.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1881..2597)
                     /locus_tag="PB779_001970"
     CDS             complement(1881..2597)
                     /locus_tag="PB779_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HDE0739490.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2927..3532
                     /locus_tag="PB779_001971"
     CDS             2927..3532
                     /locus_tag="PB779_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HDE0739491.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3857..4180
                     /locus_tag="PB779_001972"
     CDS             3857..4180
                     /locus_tag="PB779_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDE0739492.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4362..5732
                     /locus_tag="PB779_001973"
     CDS             4362..5732
                     /locus_tag="PB779_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HDE0739493.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
     gene            complement(5862..7163)
                     /locus_tag="PB779_001974"
     CDS             complement(5862..7163)
                     /locus_tag="PB779_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HDE0739494.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(7393..9351)
                     /locus_tag="PB779_001975"
     CDS             complement(7393..9351)
                     /locus_tag="PB779_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HDE0739495.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(9528..9794)
                     /locus_tag="PB779_001976"
     CDS             complement(9528..9794)
                     /locus_tag="PB779_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDE0739496.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="PB779_001977"
     CDS             complement(10304..12430)
                     /gene="pnp"
                     /locus_tag="PB779_001977"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HDE0739497.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="PB779_001978"
     CDS             complement(12618..12887)
                     /gene="rpsO"
                     /locus_tag="PB779_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HDE0739498.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            13138..13701
                     /locus_tag="PB779_001979"
     CDS             13138..13701
                     /locus_tag="PB779_001979"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HDE0739499.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(13954..14475)
                     /locus_tag="PB779_001980"
     CDS             complement(13954..14475)
                     /locus_tag="PB779_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HDE0739500.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(14478..15320)
                     /locus_tag="PB779_001981"
     CDS             complement(14478..15320)
                     /locus_tag="PB779_001981"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HDE0739501.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTATHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(15313..16038)
                     /locus_tag="PB779_001982"
     CDS             complement(15313..16038)
                     /locus_tag="PB779_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HDE0739502.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            16214..16510
                     /locus_tag="PB779_001983"
     CDS             16214..16510
                     /locus_tag="PB779_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739503.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            17078..18670
                     /locus_tag="PB779_001984"
     CDS             17078..18670
                     /locus_tag="PB779_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HDE0739504.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            18683..19423
                     /locus_tag="PB779_001985"
     CDS             18683..19423
                     /locus_tag="PB779_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDE0739505.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
BASE COUNT         5580 a         4002 c         3702 g         6223 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaaa cagttggctg gtgactgttc aaaaagcaga atccttgctt
      421 ttcaaacggt cgcagtccgt tcaactgttt cgctgcgcac tatttatggt ttaagaaact
      481 agctactttt gttgtaatca aatcaatagc aacgtggttt tctccgcctt ctggaacaat
      541 gatatccgca tagcgcttcg ttggttcgat aaattgatga tacatcggtt taacaactgt
      601 caaatattgt tcgatcacgg agtccaatgt gcgtccccgt tcttccatat cccgtttgat
      661 acgacgaatg atacgaatgt catcatctgt atctacgtat actttgatat ccatcaagtc
      721 acgcagacgt tcgtcttcta aaatcaggat tccttctaga atgatcactt cttttggttc
      781 ctgaatgatc gttgcctgac ttcttgtatg cgctacatag tcatacacgg gtttttcaat
      841 ggctttatag ttcagtaagt cgcctacatg ctgaatcagc agatcattat caaaggcaaa
      901 tgggtgatcg taatttgtgt tcaatcgttc ttcaaaactc aaatggctct gatccttgta
      961 ataagaatct tgttcaagca tcatgatgga atggtccggg aagttgttga aaatcgcacg
     1021 gctgacactt gtctttccgc ttccggatcc acccgtcaca ccaatgataa ttggcttgct
     1081 ttttgtcatt gactaaaacc tctttcgtat ccgttttttc attctaatct attatagcga
     1141 aaaaacacga aaatgctata tttttctgaa aattaatcct tttcaatttc caataatgaa
     1201 taaagttcct ctaatgaatc gattcgataa gtaggctgga tttcttcgat ttctggtaat
     1261 ttatttctat tgaaccaaat cgtatcgatc cctgccatat ttcctccttt gatatcagaa
     1321 gtcaaagaat caccaatgat cacagtttgc tttttatcaa aattaggaat gtgggaaaag
     1381 acatgatcaa aaaattcttt catcggcttt tgcgctccga cagcttctga gacaaagata
     1441 tccttgaagt aatcaagcat tcctgcatct gttaatcgcc gatgttgcgt gtgcgacaca
     1501 ccgttcgtca caatataaag atcagcatgc ggatggacct ttttcaggat ttctagactt
     1561 cctggaacaa gatcatgacc ttggttcaag tagtggcggt agcgtttttc catttgatca
     1621 ctatctactg ttttcccaaa ttgctggaaa agtaacccaa aacgactgcc tattatttct
     1681 tctcgtgata gtctgccttt ttcaaactcc tgccataaat gatgattcaa agccttatag
     1741 ctggtttcga tttctggtgt caatgtgatt ccttgttctg caaacaaagc acttaaagca
     1801 ttggcttcag ttaattgaaa atctaacaat gtatcatcta catcgaacaa taaagtttta
     1861 tatttcatct ttttgacctc ctatttaaaa taaatactta actttttcat ctctgctaat
     1921 gtcaacgatc gatactcgcc tactcctagc tgttcatcta attccaatgg tcccatgctt
     1981 agccgtttca atgcggtcac tttctttcct tgggctaaga acatcttttt gacttgatgg
     2041 aattttcctt cttggatcgt caataaaacc gtactttggt gcttgtctgc tttgagtatt
     2101 tttaaatcag ccggcttaca ttgataccca tcagcgaata cgattccatt ttcaaatgct
     2161 gttacgtctg ccggtgtcac cctttcgttc acaactactt gataagtctt tgaaaccttt
     2221 ttttctggaa gtagcatttc atatcccaat tgtccattcg aagtgatcag caatagtcct
     2281 gttgtatctc tatctagtct tcccactgga tataatggtt ggaaacgatc ggcacttgca
     2341 atcagatcga ttactgtcgt cttttctgga tctgatacag ctgtaacagc tttttcaggt
     2401 ttattgagaa gataatagga ctcatttgtt tctaagtgtt cacctgctac ttcgatttga
     2461 tgcagtaaac tatctacatt tcgattttgt cgaaattcga ctgtgccatc tatcatcact
     2521 tgcttcaaag caaacagccg cttcatttcc ttgcgtgtcg tttctaattt ttcttctatt
     2581 aatttatcta aacgcatgct gtttcctttc ttattactac taattaatta taccttgaat
     2641 attcttgctt gcaaatacat catcatagtt attccttgac ttaattaaca gttcacgtta
     2701 cggttaaata gtaaagtgaa ttggatttct catacacagc gtaatgacct ggtggagaaa
     2761 agttgaatcc tgactttcta aggggagatg cgcgcatctc tccttttgcg cttttttaag
     2821 cgccctgcct tcgatgatgt gcacgagatt agcctttaga attcacttaa ataaaatctg
     2881 tccgttacca aagcagacag tcacatttta aggaggaatt ttggttatgt cagtatcatt
     2941 agaagtaagt aaaagagaag tacgtccccg ttcattaaga aacaaacttc gtcacgaagg
     3001 gaaagttcca gctgttgttt atgggtataa agtagaaagt acccctatct cattcgatgg
     3061 tttgacacta agcaaattgt tgcgtgaaca tggagcgaac acagtcatca cgatggacat
     3121 cgatggacaa aaagtcaata cattggttca caagatccaa acgaacactt ttaccaatca
     3181 tttcgaacat gcagaatttc tatctgtaaa catgtcggaa gaaacagaag tcgaaacaga
     3241 agtcgttctt gttggcgaat cagtgggtgc taaatctggt ggagtgttag ctcaaaactt
     3301 gtatacagta gtcgtatctg ctacaccaga caaattgcct gaacgaattg aagttgacgt
     3361 gacaaacttg gaattaggtg attctattac agtagccgat cttccaaaaa acgacgatta
     3421 caaattcgtg accgacagtg aagagcaaat cgctgctgta gtcgctcaaa gtgaagaaga
     3481 aagcacaggt gaaggtggcg aaccagaagt gatcggttca acagaagaat aatactgaaa
     3541 caatcaggtg gtgttagaag cggcgggtca gcagctttta acacgccttt tttatttcta
     3601 atcgtttatt ttcatatggg gcttccactt ttgtaaatgg ctttacaaac gaaaaatcct
     3661 aatttaccaa gcttttcctc gcatactttt atcgtacctt tataaaaatt tatactttga
     3721 aaaaaagtat tcaattattg ttgcattttt cctgattctt tattagaatg aaccctcgtt
     3781 gaagtaagta tttctagttt atcctaggat taattataaa aataaaacat tcgttgattc
     3841 gaaggaggtt aaacagatgt ttgaaagttt tgatagcagc cgcaaccgtt acgcttcagt
     3901 tggtgtcgta tcaagtttgc cagatgaatt gattgacagt atatggttta ttattgacct
     3961 agatcttaag ggagtcattc cattagaaaa tatattaacc tttgatttga tcgaaaatcg
     4021 tggaaaagtg acgatgcatt tttctcaagc aggaagcaat gtggaaatgg atattgattt
     4081 gccgtttgcc tattcgaacc aatttcctgc tcaagtatac gcctatgatg acggtacgag
     4141 agaaacgatc cttttaccaa gtgagattag acaatattaa ggtgatagat aaacgtggat
     4201 gtcccttatt ttacagacca ggccaagttg ttgattcttt gactcaattc ttggcttctt
     4261 tttatggagt ttcataaatt atcattgatt tctaattggt attctcagga taaacgctat
     4321 atactactaa ctaaatttta aagatataag gagtttaaaa gatgcgcgat ttaacaaaag
     4381 gaagccccgc taaactgatt ttgatgttca ctgttccttt actgatcgga aatgtttttc
     4441 agcagttcta caatatgatc gatatgatca tcgtgggtca gacgctaggt aaaaatgcgc
     4501 tggcagcggt tggtgcaact ggaagcctga catttttgat cattggcttt gcccaaggtt
     4561 taacagctgg tttagccatt attaccgcac aacgttacgg tgcaaaagat tatcggggtc
     4621 tgaagaaaag ttttgctgct agtgttgtca ttagtcttgt cgtcactgtg attttaactg
     4681 tcctaagtct cctgtttatt cgtccgatgc ttcaattgat gcaaactcct cctgaaatac
     4741 ttgatcaagc acaaacattt atttcaatta ttttattagg gatctttgca tcagtcagtt
     4801 tcaatttgct ttctaatgtc attcgcgcac ttggtgacag ccgcacacca ctattctttc
     4861 tgatcattgc ggtcatcatc aacgtcgtac ttgatttgat ctttattatc tattttggca
     4921 tgggtgtgga aggtgcagct attgctacag taatcgcaca agtttcttcc agcgtactgt
     4981 gtctagtgta tatcaagaaa aaaatgcctt tgttacagtt acgcaaaaaa gatttcaaat
     5041 ttgaaaaaga agagtttgct gtacacctaa atgctgcttt gccaatggcg tttcaatctt
     5101 cgatcatcgc tgttggtgct atcgtgttac aagcagcact aaatagtcta gggacagatg
     5161 tcgtagctgc tcaagccgct gctggtcgta tcgaccaatt tgcaaatcag ccgatgatgt
     5221 catttggtat tgcaatggca actttcactg cacaaaacta tggtgcgaaa gaatatggcc
     5281 gaatcttgca aggggtacgt caaactttac tgatgagtgt cggatttagt ctcttagcag
     5341 gtgctatcgt cattttcttc ggtcatttct ttgttcaatt gtttgttagc ccatcagaaa
     5401 cacgtgtatt tgaattagca caaacctact tcaatatcaa tgggtctctt tactggatct
     5461 tagcagtcct gttcatttta cgctacacac ttcaagggct tggacaaagc aagatcccta
     5521 cgatcgccgg tatgatggaa ttgcttatgc gttcttttgc agctatcgtt cttacaggaa
     5581 tgtggggata cccaggagca gcagcagctt ctcctttagc ttggatcggt tctgttgccg
     5641 tgttgcttta ctcttatatg cgttcgatga aacaattgaa acacatgggt gaagaggaac
     5701 atttcacatt agaacatgca gaagcaagat agccttgatt aaaagaaatc gttgcggcta
     5761 aaaatgaaaa cttttattga aaatatcttc ttcgtttacc gaaaacaggt tttttagata
     5821 acaaaaaggc tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc
     5881 gtggactcta ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg
     5941 aatgatgcaa tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag
     6001 cccgcaagtg tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc
     6061 tggaaatcat ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct
     6121 atcaatgctt cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata
     6181 tcttcaatcg tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc
     6241 tttccctttt ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg
     6301 atcggctctt caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc
     6361 aaatctggca aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag
     6421 cgagtatgtc cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg
     6481 aatacttgca tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca
     6541 aacacgtttt ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc
     6601 aatgcgacta atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc
     6661 acacctaata gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac
     6721 attactttat aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg
     6781 acgatactat agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa
     6841 ataaatccca gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg
     6901 atcactggtt ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg
     6961 gttagcgtaa ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga
     7021 agagctagct tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg
     7081 attttcacta aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat
     7141 aaaataatga aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt
     7201 tctacaaaaa gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc
     7261 atttttcagc cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc
     7321 tttttcatga cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc
     7381 aaagcgctac tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag
     7441 cggaacagtt tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt
     7501 agcgattttt ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt
     7561 tgtcacattg gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc
     7621 tggtgtcaga gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg
     7681 gatgacttgg cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt
     7741 cacttggaca ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc
     7801 atccgtcact tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa
     7861 aatcgaatag atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac
     7921 cacatttgtc tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat
     7981 ataatctctc aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca
     8041 aataaacatc acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa
     8101 gaatttgaca acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac
     8161 taaatatgca agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt
     8221 tgtcatcaac atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt
     8281 tcggaatgtg acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat
     8341 atacatttgc ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa
     8401 cttgattgct tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac
     8461 tgcagcgact gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa
     8521 gaatggattc aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca
     8581 cgcagcctgc ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg
     8641 aatatttcgt ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc
     8701 caggaaaata tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg
     8761 gatagcataa taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa
     8821 tcccattacg cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac
     8881 aatatctgta ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat
     8941 gacgatcacg ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc
     9001 ttcaatcgca gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc
     9061 tcctccgatc attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag
     9121 tgagaaaatt ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat
     9181 tgttgtcagt agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg
     9241 attgattcct gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact
     9301 tgtcccgatg tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt
     9361 tttggtattg tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt
     9421 aggtaagctt gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt
     9481 ctaattatcc aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt
     9541 ggacgttctc tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc
     9601 aataatgctg gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat
     9661 tcgccgagcc aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact
     9721 tcctttccta aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat
     9781 aaaaaattca gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt
     9841 tattcagaag gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca
     9901 aaagtgttca gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg
     9961 aaatcagcgg tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt
    10021 gccgtttttt gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg
    10081 taaaaaagct gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt
    10141 tttaacttgg ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa
    10201 aaaaggactg tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc
    10261 tgtcaccttc acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt
    10321 tcgttgaacc atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat
    10381 cgatttcagt tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat
    10441 tgacacgatc gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt
    10501 tgacgaatgc accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt
    10561 tgacttcttt ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag
    10621 ctgaagcaat acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga
    10681 tgattccgtt gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga
    10741 tctggatcat ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg
    10801 ttgaagtcaa ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag
    10861 ttaggatttg ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat
    10921 cttttgtacc ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat
    10981 cagttaggat cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg
    11041 gcgctttgat tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt
    11101 gggaagaaga accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt
    11161 cttcttctga agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt
    11221 cccgacgccc tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt
    11281 agtggtggat gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc
    11341 ctagaggtgc gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg
    11401 atccatgtac acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt
    11461 tacgcccgtc aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa
    11521 gatcttctgt gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa
    11581 atttctcagc ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag
    11641 caagtttttc ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt
    11701 cttttttcaa tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg
    11761 cttgaacgat ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca
    11821 atgcaccaag catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg
    11881 cttgtttcgt tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg
    11941 gattcaagac gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa
    12001 atgggatatc tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg
    12061 agcagtctgt ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt
    12121 ctgcaaacat cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac
    12181 ttggacggcc ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt
    12241 cttcataatt gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag
    12301 ctgcacttaa gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg
    12361 ctagctgacc gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt
    12421 tttctgacat aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa
    12481 aactgccgaa agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt
    12541 gatcacggaa ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc
    12601 actctttttg actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt
    12661 tgaacgtcag ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt
    12721 aggccgcggt atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg
    12781 atttcttcag ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga
    12841 gcgtattcgt tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct
    12901 ttcgattatt cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt
    12961 catgtgccta gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta
    13021 atcattaaga aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa
    13081 actataatgc gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg
    13141 attacaatgg atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa
    13201 gtttctcttc cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta
    13261 aaaaacagcc aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta
    13321 gctgctcctc aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac
    13381 ccagaggcag atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat
    13441 tctgttcaag atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta
    13501 ccaggatatg ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa
    13561 aaacacaaga ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat
    13621 atcaacggtg tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa
    13681 ggcgtattgg tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag
    13741 ctttataaaa aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa
    13801 tcgaaattta gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg
    13861 catcttttct tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa
    13921 tagtttctag gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc
    13981 agctagtttt tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag
    14041 atggatgccg cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat
    14101 aaaggaatcg atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag
    14161 gggatgttcc acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc
    14221 ttcttctgtt tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt
    14281 ttcttctgtt tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg
    14341 tagtaaagca atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt
    14401 gctagcactc actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt
    14461 ctctccttcg atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc
    14521 atcaaatcaa catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta
    14581 acaactttat ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct
    14641 tttttcactt gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac
    14701 tctcgatcga tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct
    14761 tcctctactg tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa
    14821 gatttggtca caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc
    14881 gtgacgataa ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac
    14941 tccagaccgc tgttacgttt cactggatgt agtggatgcg tcgccgtgta aagctggaca
    15001 ttcggagcga acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa
    15061 ttgaaatttg cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata
    15121 actggctcca tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat
    15181 cgcagttccg ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg
    15241 tcggcaacca gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt
    15301 tcggttttga attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc
    15361 tccgtcttct tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac
    15421 taagattttg gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa
    15481 actcgttcca acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat
    15541 gactccatct tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca
    15601 tgcttgatgt ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg
    15661 acaatgacat tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc
    15721 gtgcaaaccg tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc
    15781 tatttccaaa tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg
    15841 atagaattta tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc
    15901 catcccgtgg tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac
    15961 ccctgcaccg gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc
    16021 tactgttaat tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa
    16081 atttattgtt gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat
    16141 ttatcacaat gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt
    16201 gaggtgaatc gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc
    16261 ctggttagcg ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa
    16321 tctttgggct tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc
    16381 cgtatatcga acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt
    16441 agccatttat ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc
    16501 ggcagcttaa atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt
    16561 ttattgtatt acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat
    16621 tcacattttg attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc
    16681 aaaaaccagc agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa
    16741 ataactgaat acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg
    16801 tggagtgaag caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt
    16861 tgcttggagt gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc
    16921 taagttgcgc tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta
    16981 tatctataaa tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga
    17041 ccgctcgtgt atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt
    17101 tgccgtacta tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga
    17161 tgaaaaaaca ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa
    17221 ctggtctcaa caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc
    17281 cggcggttat gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt
    17341 catcgtccaa acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc
    17401 gatcatcgcc ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc
    17461 ttattacgaa tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa
    17521 aagtttagca gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac
    17581 tgtgatcgat cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat
    17641 gagaacagct ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt
    17701 aacggcaact agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt
    17761 ccagacaaac ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat
    17821 ccaaaaagta aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga
    17881 ccaagcagtc aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc
    17941 tgatttcact acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac
    18001 cttgttcatc gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt
    18061 cttccgttcg gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa
    18121 tgcacttctt tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat
    18181 ggtcatcttc tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc
    18241 tttgtttatt gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat
    18301 ttttgcagta gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca
    18361 aacgatgaga aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa
    18421 tgagtttgtt atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt
    18481 gttcttccaa ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat
    18541 cgtcgggatc atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga
    18601 aaagaaaatc gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt
    18661 gcaggaataa ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa
    18721 aagcttcggt gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt
    18781 tgtgacgatc atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt
    18841 actggaaaaa ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa
    18901 atataattta cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt
    18961 caacaatatg aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga
    19021 taaagaaact gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta
    19081 tatcgaagcc aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg
    19141 ggcattatca atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc
    19201 tgaaatggtt ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat
    19261 gcttatcgtg acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat
    19321 ggataaaggt gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga
    19381 agaacgtaca aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg
    19441 gacaaagagc tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat
    19501 ttctgaa
//
LOCUS       DAMEEU010000056        18970 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.057, whole genome shotgun sequence.
ACCESSION   DAMEEU010000056 DAMEEU010000000
VERSION     DAMEEU010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18970)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18970)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18970
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.057"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(25..600)
                     /locus_tag="PB779_001986"
     CDS             complement(25..600)
                     /locus_tag="PB779_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HDE0739506.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(605..1579)
                     /locus_tag="PB779_001987"
     CDS             complement(605..1579)
                     /locus_tag="PB779_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HDE0739507.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(1603..1647)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            1862..2830
                     /locus_tag="PB779_001988"
     CDS             1862..2830
                     /locus_tag="PB779_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0739508.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            2927..3220
                     /locus_tag="PB779_001989"
     CDS             2927..3220
                     /locus_tag="PB779_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HDE0739509.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIVDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            3338..3574
                     /gene="secG"
                     /locus_tag="PB779_001990"
     CDS             3338..3574
                     /gene="secG"
                     /locus_tag="PB779_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HDE0739510.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            3677..4432
                     /locus_tag="PB779_001991"
     CDS             3677..4432
                     /locus_tag="PB779_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDE0739511.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            4435..6792
                     /gene="rnr"
                     /locus_tag="PB779_001992"
     CDS             4435..6792
                     /gene="rnr"
                     /locus_tag="PB779_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HDE0739512.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            6814..7278
                     /gene="smpB"
                     /locus_tag="PB779_001993"
     CDS             6814..7278
                     /gene="smpB"
                     /locus_tag="PB779_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HDE0739513.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            7580..8299
                     /gene="atpB"
                     /locus_tag="PB779_001994"
     CDS             7580..8299
                     /gene="atpB"
                     /locus_tag="PB779_001994"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HDE0739514.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMMTSLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            8352..8567
                     /gene="atpE"
                     /locus_tag="PB779_001995"
     CDS             8352..8567
                     /gene="atpE"
                     /locus_tag="PB779_001995"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HDE0739515.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVIALILVFAV"
     gene            8658..9182
                     /gene="atpF"
                     /locus_tag="PB779_001996"
     CDS             8658..9182
                     /gene="atpF"
                     /locus_tag="PB779_001996"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HDE0739516.1"
                     /translation="MLNQLAIAEVGNAMLGNIIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            9169..9711
                     /locus_tag="PB779_001997"
     CDS             9169..9711
                     /locus_tag="PB779_001997"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HDE0739517.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYEYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMDYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLEKMRNQLNR"
     gene            9734..11290
                     /locus_tag="PB779_001998"
     CDS             9734..11290
                     /locus_tag="PB779_001998"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HDE0739518.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGSNSST
                     EDKLKSIQNA"
     gene            11304..12206
                     /locus_tag="PB779_001999"
     CDS             11304..12206
                     /locus_tag="PB779_001999"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HDE0739519.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMFQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            12229..13635
                     /gene="atpD"
                     /locus_tag="PB779_002000"
     CDS             12229..13635
                     /gene="atpD"
                     /locus_tag="PB779_002000"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HDE0739520.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            13649..14071
                     /locus_tag="PB779_002001"
     CDS             13649..14071
                     /locus_tag="PB779_002001"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HDE0739521.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
     gene            14540..14770
                     /locus_tag="PB779_002002"
     CDS             14540..14770
                     /locus_tag="PB779_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HDE0739522.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            14867..16168
                     /gene="murA"
                     /locus_tag="PB779_002003"
     CDS             14867..16168
                     /gene="murA"
                     /locus_tag="PB779_002003"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HDE0739523.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            16181..16357
                     /locus_tag="PB779_002004"
     CDS             16181..16357
                     /locus_tag="PB779_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDE0739524.1"
                     /translation="MSNQRYILLTLIKILVVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            16492..16788
                     /gene="yidD"
                     /locus_tag="PB779_002005"
     CDS             16492..16788
                     /gene="yidD"
                     /locus_tag="PB779_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HDE0739525.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            16852..17319
                     /locus_tag="PB779_002006"
     CDS             16852..17319
                     /locus_tag="PB779_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739526.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASNQTRIIIRTGTTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            17404..18288
                     /locus_tag="PB779_002007"
     CDS             17404..18288
                     /locus_tag="PB779_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDE0739527.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKTQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLD
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLIGAAANYLAVRQGEN"
     gene            18402..18638
                     /locus_tag="PB779_002008"
     CDS             18402..18638
                     /locus_tag="PB779_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HDE0739528.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            18726..18806
                     /locus_tag="PB779_002009"
     tRNA            18726..18806
                     /locus_tag="PB779_002009"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18760..18762,aa:Tyr,seq:gta)
     gene            18813..18884
                     /locus_tag="PB779_002010"
     tRNA            18813..18884
                     /locus_tag="PB779_002010"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:18845..18847,aa:Gln,seq:ttg)
BASE COUNT         6290 a         3317 c         4107 g         5256 t
ORIGIN      
        1 ttttgctaat ccagctctgt ttattcagcc tatttttctt tttgaatata tcaagcgttg
       61 tggcaacata gtgatgacta atgaaacaac gacgatagac aacaaacgat caaggtagtc
      121 tgtacctgcc tgtaccaaga tcacacttgt tgtctgactt aaacctaacc catgtaatag
      181 ctgaacgatc atactggatc ctgaggaggt gatcccgcca aataactgaa cggtaatgat
      241 cgaagaaacg atcgttccag gtaccgacaa aatcaaagcg agtaataaca gtttcaagct
      301 gtttttatct ttgccgagat atcttggcaa aatcaatcca gcaagcaagc ctgtgagaat
      361 ttggattggc gaataataca gagaaaaaat atctgtagtc actccactta aaataccgct
      421 ggacaatcct gtcagcattc caggtacagg cccaagcaat gcaccagcaa aaatcgttcc
      481 gatagaatcg agatagattg gcaaacgaag ccataaagca atcgttcctc caatataatt
      541 gatcccaata cacaaagcca tcactgtaag tacgcgagtt gccattttgt ttttattcat
      601 tttgttagcc catctttaac ctttccaaat ctttcataat cgtttcttct tgtgcattta
      661 aaagaacggt taaaaacttt cggaaaaaaa gacgagtatc tacttttgtc ataattttac
      721 tgttagcagg tttctgccaa aattcataac gatcaaccaa tgtttgtcca cgacttattc
      781 cttgagtttc cacagcagtg aagcttttga aaccttcaca gatggcctcc tcgataaaat
      841 aagcaacagc taacggatca ttgatgacac atcctaaaat tctttcttgt ttccagtgga
      901 agtcaaaata aaaacgagtg atcgctttta gatactctcc ctcttcagga ttcatttgac
      961 agcagtattc gaggatagtc ggtgtcaaga cgatttctct tgtcacatct aacccaacca
     1021 tttctatcgt ttgtttgaga ttctcgaata cataagaagc tgcttcagga tcacaccagt
     1081 aattgtattc agcaactggc gaacagttac catggctttt gtaagttcca cccatcgaga
     1141 caaaacgttc catatgtttc ccaatatttg ggttgacttt caaagcagaa gcgatattgg
     1201 tcaaaggacc caaagcaatg actgatgtat ttgtcttttc tttgaaataa tcagccaaaa
     1261 aatcaacggc atggagaggt tctgcctgtt ttctcaagat catcgggaaa tttgtttccc
     1321 ctaaaccatc cataccatga gtgtcttgtg cactgatgaa aggttgcttc aaaggttttt
     1381 ccattccttg ataaacagga atgtctaaac gatcacagcg ttccaggcat ttcagcacat
     1441 tctgcgtacc tatatctgca gggacattcc cacaaactac ggtaatagca actacttcga
     1501 tatcagggga tttgacagct aatgataaag ctaaagtgtc gtcgatccct ggatcgcaat
     1561 caataattac ttttcgcatt atttccaatc tcctttcttt agagatactt agttttttat
     1621 tctgggaagt ttccgaacca gtccaagacg agcgtcttga ttataatgca cgaaattagt
     1681 atactggctt ttattgcgaa tgtaaatgct ctcttacaag taaatctatt gaggagaact
     1741 ttaagtaaat gatacaatga aaaagaaatg gaatttacgt gtgccgaaaa taaagaatcc
     1801 tatggatcgg tacattggat aatagataga ttatagtttg gcagaaagcg gcgggtgtac
     1861 aatggttatt ttttatttca ttcttattct gataattata gggatcagtt accattttct
     1921 ttcttatttt tatgcaaaga aattagtaag agcgggagta cagagaggat atgactggta
     1981 tgaagacact ggtcatcgtt tgatggaccc tgctgcagtc acgtcagtag aaaaaaaacg
     2041 acaaaaatta gaagaagagt gtgaaagctt ttgggagcag ggaacaccca aaacaatcaa
     2101 aagttatgac gggttgaaac tagctggtca gatgttcatc catccaaata agcagaataa
     2161 atgggtcatt tgcgtacatg attaccgaag cacagggaaa agagacatgt ctcatatagg
     2221 taaaagatat gcagagaaag gattcaacgt tcttgtacct gatttacgtg cgcacggaga
     2281 aagtgaagga gaaatcatcg gaatgggatg gctagatcgg ctagatttaa ttgcctggat
     2341 ccaactcatc ttagatgaac agccgaatgc gtccattatt ttacacggcg gatcaatggg
     2401 agcttctacg atcatgatgg caagtggtga aaaacttcca tcagcggtca aaggatttat
     2461 tttagacagc ggatatgttt ctgtttatgc agaattccga tatatgttaa gtaaaatcac
     2521 tgtctttcct aaaaaaatgg tcatgagata tgcgaatcat tatgcccaga aatacgccgg
     2581 ttactcctta aagcaagcat cagctacgag acagcttggc agcaatcatc tgcctttatt
     2641 agtcatccat ggtgaaagag atcattttgt ccctacagaa gcagcgtaca cgattcaaaa
     2701 tgctacggca ggggataaag cactgctgct tgttccggaa gcagaacact tggaagcatc
     2761 gatgaaagat ccgaaaacct attggacagt gattttttca tttattgaac aaagaataac
     2821 gatgaattaa ttttctcttc ttttttgtaa gtaattcgag gataaataat tgtttataga
     2881 tcaggagact gctaaaataa ggtaggaata aaaaaatatc agttatttga ggagtgcggc
     2941 atatggaaat caaagaagaa aaaatcgtct tgctttattc aatgatgaac aacaagagat
     3001 cggagaaatg acatggtcag atgcgggccc agacatcatg atcgttgacc atacatttgt
     3061 agatccagca tatcgtggtc aaaagttagc tgaaaagcta gtgtatactg gagtagaatt
     3121 agcaagacga gacgggaaaa agatcattcc tttatgccct tatgcaaaaa aagagtttga
     3181 aaagaaacca gaatatcaag acgtcttacg tcagtcataa gaataacagc tgaaagtttt
     3241 gaactttcag ctgttattcc atttatatag agttgtcacg gacttttatc tatgataaag
     3301 ttaaagagac gatatctttt gggaaggagg ctgcgatatg tataatttaa ttttgggaat
     3361 cgtgatcgtt ttatcgattg ttatggtcat tgcgattatg atgcagccaa gcaagcaaaa
     3421 tagtgcagcg agtgcattta ccggcggtgc ggatcaacta ttcggcaaac aaaaagctcg
     3481 cggctttgaa gctgtcatgc agcgatcaac tgcagttatg ggagctatct ggatgatctt
     3541 attatttgtc ctagcatatt tatcttcgaa gtagttgaat aagcctctcg caaaacggcg
     3601 ggcggctttt tttattgcaa agagaacgct taagaagaag ttatgaaaga aactatggta
     3661 aaatgaggcg aaagaggtga gacgagtgag acaattacca aaaccccttt atgcaaaaca
     3721 tggaaagcga gcggttttgc tgcttcacgc ttactcagga agtccaaacg atgttcgaat
     3781 gctcgcacga tttttggaaa aagcagatta tacagtttat gcgccgcttt ttaaaggaca
     3841 cggaacaatg gagccatatg atatcttgca agaaaaagca gaaagctggt gggcagacac
     3901 taaaaaagcc atccattttt tacagtctga gcagttttct gatattgccg tattaggatt
     3961 atcaatgggc ggcatctttg ctgtacgagc actagaagaa gaatcagtga ttggcggcgg
     4021 ttttttctgt tcgcctttgt ctcctgtaaa aacaaacgtg cctgaaaact ttgaaaaata
     4081 cgtacgtcaa gtgctgaaga cagcaggtaa atcagagaaa gaaatcaatg aaaaagcagt
     4141 tgcttaccgc tcgttagctg aacaacaatt aatggatata caagatcagg cagcaatcgt
     4201 agaaagtagg ttgtcagata tccaacagcc gatattttta gctcaagctg ggaaagatga
     4261 aatgatcgac cctaatggcg tatttgaaac tgcacgcaag ttgagccgtc agcgagtgac
     4321 acttcaatgg tatcctgaaa gtggtcatgt gattacagtt ggtacagcaa gacgcgaatt
     4381 agaaaaagac gtcttggaat ttttagaaaa attaccttgg aatgaggaat aaatatgaca
     4441 aaagaaacga taaaagagaa aattctcttt ttcatggaaa gcagtcgcaa acgcagtttt
     4501 tctatggaag aaatcgctga aggtttaggg ttccaaaaaa gcgatgattt taaattacta
     4561 gtacaaacga ttgctcaaat ggaaagagaa cagagtatag ttttcaataa aaaaggaaaa
     4621 gtgaaacttc ctttaaaacc aatcctgatc gaaggaacat ttcgagcaaa tgaacgagga
     4681 tttggatttg taacgattga tcccgaagaa gatgacatct atatcccaaa agaagcgact
     4741 ggttttgcaa tggatggaga caccgtagca atcgatatca tgaagcgagc aaatacagat
     4801 atggatcgcg gagcagaggg gaaagtagtc gagattcgag accgggcgac tactcagtta
     4861 gcaggggaat tcgttgctta ttcagaagaa gaaatacaag aaacagatct ttacggcgtt
     4921 gttatcccga aagatagaaa gctcaaccaa tttaaagtat atgcagcagc agagggagtt
     4981 cgtccagttg acggaagtat tgtgctgatc gaactgaccc attaccctga aaaagggtat
     5041 gcgactagtt tagaagggat aatcaagcaa gtgattggtc ataagaatga ccctggcatg
     5101 gatatcctct caattgtcgt ggctaatggt atccctacga aatttcctga tgatgtattg
     5161 tctgaagcag atgaagttcc agatcaaatc agcgaaaagg atataactgg acgtagagat
     5221 ttaagaaatc agctcattgt tacgattgat ggagaagatg caaaagatct agatgatgca
     5281 gttacggtta aaaaattaga taacggtaat tattttcttg gagtacacat tgcagatgtt
     5341 tcttactatg tgacacaagg cagtcaattg gacagagaag catatgaaag agggacaagt
     5401 gtatatttga ctgatcgagt aattccgatg atcccgcaac gtttatcgaa tggtatctgt
     5461 tcactgaatc cccatgttcc aaggctgacc atgagttgcg aaatggagat tgatccaaat
     5521 ggacaagtag tctctcatga tattttccca agtgtgatcc aaacaacaga acggatgacc
     5581 tacacagctg tcaatcaaat cttagaagat caagacgaag aaacgatgca acgctatgct
     5641 cagctcgtac ctatgttcca agaaatgggt gaattgcacc gaatccttga aacgatgcga
     5701 atcaaacgtg gcgcgatttc ttttgaggat cgcgaagcga aaatccttgt tgatgctgaa
     5761 ggacacccaa atgacatcca gctaagaagc agaggaattg gtgaacgctt gatcgaatct
     5821 ttcatgcttg cggccaatga aacggtagct gaacattata ataaattaaa tctgccgttt
     5881 atttaccgaa tccatgaaca gccaaaagaa gaaaaaatgc agcgcttctt tgattttgct
     5941 tcagctttgg gcattctggt ccgaggaacg aaaggaacga tcacaccaaa agatttacag
     6001 catgtgatcg aaggagtaga agacaaacca gaagctgcag ttatcaatac tatgttgcta
     6061 agaagcatgc aacaagcacg ctattcagaa gacaattttg ggcattatgg cttagcggca
     6121 gattactaca cacactttac atctcctatt cgacgctatc ccgatctaat cgtccatcgt
     6181 ctgatccgtt cttacagtga agataaaagt gaaagcaatc aaagttcgtg ggctgcggaa
     6241 cttcctgaaa ttgcagatca tagttctaag atggaacgtc gtgcagtaga aacagaacgt
     6301 gaagtagatt ccatgaagaa agcagaattc atgatggaca aagtgggaga agaattcgat
     6361 gggatcatca gctctgttgt gaaattcggc ctgtttatcg aactgccgaa tacagtagag
     6421 ggattgatcc atatcaatga attgaaacag gactacttcc attttgttga aaatcattta
     6481 gctcttgtag gtgaaagaac tggtctgact tttaaaatcg gacagaaagt gcgagtaaaa
     6541 gtagtcaaag ctgatccaga tgaacgagca gtagattttg aacttgtttc cgcagaagag
     6601 gttacagcgt tggaacggcc aaaaacacga aatggaaaat caggaaaacg cgaaggaaaa
     6661 caagcaggaa aacgcccaga aagaaatggc aagaagaaca aacgatatag cgatagtaag
     6721 caaacgttcg gtaagaaaaa agggaagaag ccattttaca aaggtgttaa aaagaagaaa
     6781 aagaaaaaat aaaatgagtt ggaggaaaca gctatgccaa aaggcgaggg aaaattaatt
     6841 gcacaaaaca agaaagctcg ccatgattat tcgatcatcg acacgatgga agcagggatg
     6901 gtcttgcaag gaaccgagat caagtcgata cgaaacagcc ggatcaatct aaaagatgga
     6961 tttattcgcg tccgcaacgg agaagctttc ttgcataatg ttcatatcag tccttatgaa
     7021 caaggaaata tttttaatca tgatccgttg cgcacgagaa agttattatt acacaaaaaa
     7081 caaatcatcc ggcttgaaaa tgaattgaaa aatactggaa tcactgttgt tcctttaaaa
     7141 gtctatattc gtaacggcta tgccaaggta ttgattggtc tggcgaaagg gaaaaaatct
     7201 tatgataaac gggaagattt gaaacgaaaa gatatcgatc gacaaattga tcgaacatta
     7261 aaaaatttct ctagataatt tcattatcct ttttcgcata ttcggtgctt ttgcttttac
     7321 ttaatgataa aatttgttag catttaatct gataaaacat gattatcata ggttttttct
     7381 tagatcagga gcaccgtgta taaagaaaaa ttcgcttcgt ttttgactga aataaaaaag
     7441 tgtctaattt tcatgaaaat gttttgaatt ttctgtttca tggtggtatg ataccgtgtg
     7501 gttagaaacc gattggaaaa aaccagatac gcacatgaat tgattttatg tgaatttcgg
     7561 ggaaaagagg tgaaatggat tggatgaacg ctcgctaacg ttccacattg gaccaatttg
     7621 gtttgatggt acagtttgta taatggtgtt actgacctgt ttgattgttt tcttcttagc
     7681 ttactttttt acaagaaatc ttaagttgaa accaacaggc aaacaaaatg cgatagaatg
     7741 ggtcattgat tttagtcgag gaatcgtaac agataatctg cctagaaaag aattgagcaa
     7801 tttccatttg ttggcattta cattgttttt atttgttttt gttgcaaaca acatcggttt
     7861 agtaacaaaa atcgttttac ctaacgaaac aacactttgg aaaagcccga cagcagaccc
     7921 gtttgttact ttaactttgg catttataat gatcttactt actcacttat tcggggtgaa
     7981 aaagttaggc ttcaaaggat atttcgtaaa ttcgttcttg aaaccctata gttttatgtt
     8041 tccgatgaaa ctgattgaag aatttacaaa cttattaaca cttgctttac gtctttatgg
     8101 gaatatttat gcgggggaag ttttgctaac cttgattgca aaaatgatga caagcttagg
     8161 ctggttctca ttaccattag caattccatt agagatggtc tggatcgcgt tctccttgtt
     8221 tattgggagc atccaagcat ttgtctttgt cactttgtca atggtttata tgagccataa
     8281 gattgaagta gaagaataat actcggttaa aaaacaaact actatttatc tattttagga
     8341 ggaaaacaat tatgaattat atcgcagcag caatcgcaat catgggagca gcaatcggag
     8401 ccggttatgg taacggtcaa gttatctcta aaacaatcga atcaatggct cgccaacctg
     8461 aaatgtctgg tcaattccgt acaacaatgt ttatcggggt agctctagtt gaagctgttc
     8521 ctatcttagg ggtagttatc gccttgattc tagtttttgc cgtttaattg aatcagtatt
     8581 aaggcagaaa caacatcgtt tgttactgct tttttacatg gaaactagaa atactccaaa
     8641 gaaaggaagg ctcgcctatg ctgaatcaat tggcaattgc agaagttggc aatgcgatgt
     8701 taggtaatat catcgttgtc agcggctcat ttttgatact actggctctc ttgaagcact
     8761 ttgcttgggg accaatcagc gatattttga aaaaacgtga agacaagatc gccaatgatt
     8821 tagattctgc agaacaatct cgcatcaact cagcgaaaat ggaacaagaa cgcgaacaac
     8881 aattgttagc ctctcgttct gatgcagctg atatcatcaa aaatgcgaaa gaaagtggag
     8941 aattaagccg ccaaaatatt ttgaaggatg ctcaagaaga agcagctcgt ctaaaaagca
     9001 aagcccaagc tgatatcact gtagaacgtg attcagcgct gaactctgta aaagacgacg
     9061 ttgcagaact ctctcttcaa atcgcggaaa aaatcttgaa caaagaatta tctccagaaa
     9121 tgcatgaatc attaatcaat caatacattg aaggtctagg ttcttcaaat gaaactagat
     9181 aaatatacag taggaagacg ttacgggaaa gctttatttg aactggcgat cgattcaaat
     9241 caagcagaag aaatctatca agatctcgta agtttacgtc aaatctatga acaagtacct
     9301 ggattaggga atatgttaag tgatgttcgt ctagaacctc atgaaaaacg agaaatcatg
     9361 gacaagcttg tcagcggtta tgatgggatc gttaaaaact ttttagaagt tgtttatgag
     9421 tataaccgaa tggatgacct tttgttcatg atcgaagaat atgaacgtcg atatgatgaa
     9481 catcaagggt tactattggg aagtgtcaca acagcagtcc cactttcaga cgaacaacga
     9541 atacaattag aaaagaatgt tgcaaaaaca atggactatc aatcagttga attaaaacaa
     9601 atcgttgatt cttctattat tggtggcgcg attgttgaag ccaaccatcg agtaatcgac
     9661 ggaagcattc gcacgcaatt agaaaaaatg cgtaatcaat taaacagata gtacaaagag
     9721 gtaggtgaat cgaatggcca tcaaagcaga agaaattagt gccttgatta aagaacaaat
     9781 tgaaaattat caaaacgtgc tttcagtcga agaaatcggt accgtaactt atgtaggtga
     9841 cgggatcgct cgtgcacatg gtttagaaaa cgcgatgagt ggtgagttgc ttgaattttc
     9901 aaacggctca tacggaatgg cgcaaaactt agagtcaaat gatgtaggta tcattatcct
     9961 tggcgatttc gagtccattc gtgaaggaga taaagtaaaa cgaacaggta agatcatgga
    10021 agttccagtt ggagaggcct tgatcggtcg ggtagtcaat ccgctaggtc aaccaatcga
    10081 cggactaggt gaaatcgtta ctgacaaagc tcgtccagta gaagcgatgg caccaggtgt
    10141 tatgcaacgt aaatctgtta acgaaccaat gcaaacaggg ctaaaagcga tcgacgccct
    10201 tgtgccaatc ggacgcggac aacgtgaatt agtcatcggt gaccgtaaaa cagggaaaac
    10261 ttctattgcg atcgatacga tcatcaacca aaaaggtcaa gatatgatct gtatctatgt
    10321 agcaatcgga caaaaagatt ctacagttcg tacacaagtt gaaacattga aaaaatatgg
    10381 cgcaatggat tacacaatcg ttgtgaatgc cggtgcgtct caaccagcac cattgcttta
    10441 tatcgcacca tatgctggta ctgcaatggg tgaagaattc atgtacaacg gtaaacatgt
    10501 attgatcatt tttgatgatc tttcaaaaca agctgttgct tatcgtgaac tttccttgct
    10561 acttcgccgt ccaccaggtc gtgaagctta tcctggggat gttttctact tgcactcacg
    10621 tttattagaa cgtgcagcaa aattaagtga tgatttaggt ggcggttcaa tgactgcctt
    10681 accatttgtt gaaacacaag ctggagatat ctctgcttat atcccaacaa acgttatttc
    10741 gatcactgat ggacaaatct tcttagaaag cgacttgttc tacgcaggta ctcgtccagc
    10801 ggttgatgcc ggactatctg tatctcgtgt aggaggttct gcgcaaatca aagcaatgaa
    10861 aaaagttgct gggactttac gcctagactt agcaagttac cgtgaattag aagcatttac
    10921 acaattcggt tctgacttgg atgcagcaac acaagcaaaa ctaaatcgtg gacgccgtac
    10981 agtagaaatc ttgaaacaaa aattgcatgc accgctagct gttgaaaaac aagtagtgat
    11041 tttgtatgct ttgacacatg gattcttaga tagtatccct gtagacagta ttttagactt
    11101 cgaacatgaa ttattcgaat atctggatac caatcattca gatatctttg aaacaatccg
    11161 tacaacaaaa gatcttccag aagaagaagc gttgaacagt gcgattcagg aatataaaga
    11221 catgttctta gctacaaaag gaagtaattc ctctacagaa gataaattga aatccattca
    11281 aaatgcatag tgaggtgaga tgaatgggtg cttcattaaa tgaaatcaag acacgtatcg
    11341 cttcaacgaa aaaaacgagc caaatcacgc gggcaatgca gatggtgtct gcttctaagt
    11401 tgacaaaatc tgaagcttct tcacagaagt ttcaggttta tgcaacaaaa gtaagagaaa
    11461 tcgttacgca tttgactgct actcagttaa atgatattgc ctcagaaaat cctagagggg
    11521 atatcaatta caacagcatg ctgctcagcc gtcctgtgaa gaaaactggt tatatcgtca
    11581 tcactgcaga tggcggttta gtcggtggat ataacagctc gatattgaaa caaacgatgt
    11641 ctattttaga agaagaccac caatcacccg atgattacgt gatgatcgca attggcggaa
    11701 ctggtgcaga cttctttaaa gcacgcggta tcaatctagc atatgagctg cgcaatctat
    11761 ctgatcagcc aagctttgat gaagtccgca aaattgtaaa tatggcaaca actatgttcc
    11821 aaaacgaagt attcgatgaa ttatacgtat gttataacca tcatatcaat tcgctaacta
    11881 gtcagtttcg tgtagaaaaa atgctgccaa tctcagactt agatccagaa gaagcaacga
    11941 ctttcgaaca agaatatatt tttgaacctt caaaagaaga aatcttgtct cagttattgc
    12001 ctcagtatgc tgaaagtttg atctacggtg cgatcgttga cgccaaaaca gcagaacatg
    12061 ctgctggtat gacagcaatg aaaacagcaa ctgataatgc tgctaatatc attgatgagc
    12121 tgacggtttc ttataaccgt gcaagacaag gggctattac ccaagaaatt accgaaattg
    12181 ttgccggagc ttcggcacta gaatagtatt gagattggag gaaaaaagat gagttcaggc
    12241 aagattgttc aagtaatcgg tcccgttgtc gacgtggaat tttctttaga ccaatcctta
    12301 ccagatatca acaacgcatt agttgtttat aaaaatgacg aaaataaatc aaaagttgtt
    12361 cttgaagcag cgttagaatt aggggacgga gtgatccgga ccattgcgat ggaatcaaca
    12421 gatggtttac aaagaggaat ggaagtcatt gatacaggca aagcaatctc tgttcctgta
    12481 ggtaaagaaa cattaggtcg cgtattcaac gtactaggag atacgatcga tttagaaaca
    12541 cctttcccag aagatgcgga aagaagcgaa attcataaaa aagcaccagc ctttgacgaa
    12601 ttaagtacaa gtacagaaat tttggaaaca gggatcaaag ttatcgattt gcttgcccca
    12661 tatttaaaag gtgggaaagt cggactattc ggtggtgccg gtgttggtaa aaccgtactg
    12721 atccaagaac tgatccataa tatcgcccaa gaacatggtg gtatttctgt atttaccggt
    12781 gtaggtgaac gtactcgtga aggtaatgac ttgtattatg aaatgaaaga ttcaggagtt
    12841 atcgaaaaaa cagccatggt gttcggacaa atgaacgaac caccaggtgc acgtatgcgt
    12901 gttgctttga ctggtttgac gattgcggaa tatttccgtg atgtagaagg tcaagatgta
    12961 ctgttgttta tcgacaacat tttccgtttc actcaagctg gatctgaagt atcagccttg
    13021 ttaggacgga tgccttctgc ggttggttat caaccaacat tggcaacaga aatgggtcaa
    13081 ttgcaagaac gtatcacatc tacgaaaaaa ggttcgatca catcgatcca agcaatctat
    13141 gtgccagccg atgactacac tgacccggcg ccggcaacag cattcgccca tttggatgcg
    13201 acaaccaact tggaacgtaa attaacagaa caagggattt atccagcggt agatccattg
    13261 gcttcttctt caagtgcttt agcacctgaa atcgtgggag aagaacatta taaagtagca
    13321 acagaagtcc aacacgtatt gcaacgatat cgtgaattac aagatatcat tgctatctta
    13381 ggtatggatg aattatccga tcaagaaaaa gtgttagttt ctcgtgcccg cagagtccaa
    13441 ttcttcttgt cacaaaactt taacgtggct gaacaattta ctggtcttcc aggttcatat
    13501 gtccctgtag aagaaacagt gaaaggattc cgcgaaatct tggaaggcaa atacgatgat
    13561 cttcctgaag aagctttccg aagtgttggc cgaatcgaag acgtcgtaga aaaagcgaaa
    13621 acactaggct actagaaagg ggtgccccat ggatcaatat ttaacagtaa atgtggtaac
    13681 tcctgccggt ttggtctatg atcaccatgc agctatcgtc gttgcacgta cgacagctgg
    13741 tgagcttggg attttgccta aacatgcacc aatcatcgtt ccattgacga ttgatgaagt
    13801 tcgtgtaaaa cgaacagatt cagataccca cgtcgattgg atcgctgtta atggcggaat
    13861 catggaagtt cgtgataatg ttgtttcaat cgttgctgat agtgcggaac gtgaacgtga
    13921 tatcgatgta tctcgtgcgg aacgtgcaaa acaacgcgca gaacgccaaa tcgaagaagc
    13981 aaaagcaaaa caagatacga acgaattgaa acgggcaact gttgcgttgc accgagcaat
    14041 caatcgtatc aaagtatcta agcactcata aaatgagatg cggatgttta tccgtgttta
    14101 agaacagtaa aaagaggtta tgacagaagt ggtcagcttc aagacataag aaggaattta
    14161 cgaaaattgc ttctcaaatt tttgtgaaat ctcagcttat ttttcgaaga agctacttct
    14221 ggaacaccgt atatcagagg ttgtgaaatc agcgttttgt cctgagtatt agagaaacaa
    14281 atggaaaata gttcctcata ttttgccgtt ttttgagcta ataccgaggg tcagatgatt
    14341 gaacaccgtt tatttggaat aagggactgc gacaagactt ttgtctcagt cccttttttt
    14401 gcatattttt agcatttatt tcctaaaaaa tgtaagggga ttcctatatt tttaagtata
    14461 cttgtttttc cttttataca ttttatggta ttatcatttt attagttatt ataaaacaat
    14521 cgttagaaag gacgtcatta tgcaagtata cggaattgat gcggtgcttc gaatcgtgag
    14581 tcatttggcg tttatctact tagccttctg gtctttacgt tcgttacgca ttgaaacttt
    14641 tttcagacca atgcataata cgcaaattag aatggcaatc gtactttttt caattttttt
    14701 agggtacact gcaagtaatt ttttcttaga ggttatcgct ttatgccgaa atcttttcgt
    14761 tagcctgtaa attttaaaaa aaggtactat tttaaaagca aggatgttat aatagaaaag
    14821 attttgagta agtgtatgct cattggaatt ttttggaggg aacaacatgg aagagatcat
    14881 cgtaagaggt ggcaatcaat taaatggaac agtaagaatt gaaggagcta aaaatgctgt
    14941 tttgcctatt ttagctgcta gtttgttagc agaagaaggt attacgacat tagacaacgt
    15001 tccgattctt tctgatgtct tcactatgaa tcaagtgatt cgtcacttaa acgtagatgt
    15061 agattttgat gaacaaaaga atcaagtaac aatcgacgct tcaagacaat tagaaatcga
    15121 agcgccttat gagtatgtta gtcaaatgcg tgcttcaatc gttgtgatgg gtccgctact
    15181 tgccagaaat ggacatgcaa aagtagctat gcctggtgga tgtgcgattg gtaaacgacc
    15241 aatcgatttg catttaaaag gatttcaagc tttaggagca aaaattattc aaaaaaacgg
    15301 ctatatcgaa gcaattgcgg atgaattgat cggtaacacg atttatttag atttccctag
    15361 tgtaggtgct actcaaaata tcatgatggc tgccgtaaaa gcaaaaggaa caaccatcat
    15421 tgaaaacgta gctcgcgaac cagaaatcgt tgatttagca aacattttga ataaaatggg
    15481 cgctcaagtc tatggagctg gtactgaaac aatgcgtatt gaaggcgtgg atcatttaca
    15541 tgcagtcaac cactcaatcg tacaagatcg tatcgaagca ggtaccttta tggttgctgc
    15601 tgcaatgaca caaggcaatg tgctgattgc agatgctatc tctgaacata accgcccatt
    15661 gatttctaaa ttgatcgaaa tgggtgcaga aatcattgaa gaagaaggcg gagtccgtgt
    15721 catcggacca aaacatatct tacctacaga tgtaaaaacg atgcctcatc ctggtttccc
    15781 tacagatatg caagctcaaa tgacagctat ccaattagtt gcagaaggta caagtgtggt
    15841 gactgaaaca gtgtttgaaa atcgtttcca acatttagaa gagatgcgcc gtatgaacgc
    15901 tcatgtcaaa atcgacggaa atgtagcaat catggatgga aaccatgaat tgcaaggtgc
    15961 agaagtatat gcaacagact tgcgggcagc agcagcatta gttttagctg gcttgaaagc
    16021 aaatggaatc acacgtgtgc gtaacttgaa ttatctagac cgtggatatt ataatttcca
    16081 tatcaaacta cagcaattag gtgcagacgt cgaacgtgta gacatggatc aaacttctgc
    16141 tgaaaaaaca gcacaaacga ttgcttaagg aagtggctga atgagtaacc aacgatatat
    16201 cttattaact ttgataaaga ttttagtggt gatcttattg cttatccttc tttttgtggc
    16261 cggaacgatg atcggatatg gtgtcatcgg tggcggcaat ccatttaaag tattccagcc
    16321 aagtttgtgg attcatattc gagacttttt tcattgataa ataagaatca cagtggttct
    16381 agtcgatatg aagtgagcca tgaagcagaa catgataaaa gaaaacagaa gggaacgttg
    16441 acgttagtcg cgatcccttt ttttagtaaa agaaaagaag gaatctaatt gatgaagaag
    16501 atattgattt atttagttag aggatatcag cgctttattt cgcctgcatt tccacctagc
    16561 tgccgttatt acccaacctg ttccaattat atgataaaag caattcaaac ccatggtgcg
    16621 ctaaaaggga cggtaatggg gactgcacgg atcttacgct gtcatccttt tgtcaaaggc
    16681 ggtatcgatt atgtaccatt gacattccga ttaacgcgaa ataagaaaga taaaaaagaa
    16741 ccagattata aaaaggttgt gaaaaatacg ggtagcactg agcgataaag aaaaagagga
    16801 aatttattgt caaagtaaca actccgcaac tacttatatg ggggacaaaa aatgatcgaa
    16861 gaactaaaca agaaagattt accatggtcc ttgttattag atgcagatcc tgataaagaa
    16921 aaagttcaag tatatgtttc cagagggagt ggctggatat ggaaagaaaa agaaaaaaca
    16981 ataggtgtac tgatctatgt ggcaagggaa aaagaatacg aaatcgtcaa tgtagcagta
    17041 accccaacgt atcaaggaaa ggggattggc ggaaaattac ttgagacagc ttttcagaag
    17101 ctttcacagc tagcttcaaa ccaaactcgg atcattatac gtactggcac tactagtagc
    17161 gctgcgttac acctctatca aaaaatgggc tatgtggaga ttggtcgagt caaagactat
    17221 tttatccatc attactctga gcccattttt gaaaatggag atcaattaag ggatcaagtg
    17281 attttagcaa ttcacttacc taaaaatagc tttaactaat aaactttcaa ttcgagaaaa
    17341 tgctttcaaa tgctaaatag atacattaca atagctttag caaacaaaaa ggagaatatt
    17401 tttatgggaa tattagtttt tgattttggt ggatcggctg tcaaatatgg ttgttgggat
    17461 ggcaaagaga ttaaaggtaa gggacaattt gcaacgcctg aatcttggga agaaatgaaa
    17521 acgcaattat ttcaagttta taaaaaaata ctcgtttctt ttgaagtcga aggaattgga
    17581 atcagctctc ctggagtagt gaataatgag aaacaggtga ttgagggaat cagtgcgatt
    17641 ccttatattc atggatttaa tattttccga gatttggaaa ctctgtttca actcccagta
    17701 acgattgaaa atgacgccaa ctgtgccgga atggctgaat tttatgaagg tgctgcccgt
    17761 gattatcaag atgttgcttt tgttgtggca ggaactggga ttggcggggc gttgttcacg
    17821 aaaggacaaa taaataaagg ggcacatctt tacggtggag aatttgggtt gatgttctta
    17881 gatggcgata agacattcag taaacttggt acagcggtac agatggcttg gcgttattgt
    17941 gaacgcaaag gtctcgataa aaatgcttat accggaaaag atgtctttga attagcagaa
    18001 actggagatg caatagcaaa agaagaagtt gagagttttt atacgtatct tacaaaggga
    18061 ttattcagta ttcaattttc gtttgatcca gaagtgatcg tattaggcgg cggggtttct
    18121 gcaaaagaag ggctcattga tgagatcaaa agccgaatga agaagctgac agaacaattc
    18181 gatctgcatg atttcgaacc gcagatttta ttatgtgagt acagaaacga tgctaatctt
    18241 ataggtgcag cagcaaacta tctcgctgta cgtcaaggag agaattaaga gctttagaga
    18301 aggtgcagct tgcataaaag aagagaatga aatgaatagg agatttttac ctaaggaatg
    18361 ttttatttgc tgcagtatga taaaatatct gagaggtgaa aatgatgtca aaaaaaaata
    18421 aagatattga agtgcgtata gaagaagtga aaaaagatat caaaggtaag aattatgaag
    18481 tcactcagtt atttataggg aaaaaaatga ttggtgagat cttagcctat gggccaaaag
    18541 aatatgaaat tttctttggt gaagaagatt ttggaaaaga aaaaagtctt gaaaatgcga
    18601 tagaaacagt gattcgacac tggaatctgc acgaataaaa aaatatcaaa aaaactttca
    18661 ataaagggtt gcaaaaatct ggaaaattag gtattataac taagtcaggt tgatacaaac
    18721 ctttcggagg agtagcgaag tggctaaacg cgacggactg taaatccgtt ccttagggtt
    18781 cagtggttcg aatccactct cctccatttc attggggtat agccaagcgg taaggcaagg
    18841 gactttgact ccctcatgcg ttggttcgaa tccagctacc ccagtatacc acaatcgtaa
    18901 gctctcgtta gttcgagagc tctttttttt tgctttgcta ccttgttcct tgaagattct
    18961 gctgaattaa
//
LOCUS       DAMEEU010000057        18594 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.058, whole genome shotgun sequence.
ACCESSION   DAMEEU010000057 DAMEEU010000000
VERSION     DAMEEU010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 18594)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18594)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18594
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.058"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..299
                     /locus_tag="PB779_002011"
     CDS             <1..299
                     /locus_tag="PB779_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739529.1"
                     /translation="DYTVEFDSELLKQFPQEEHFMYKEAISHKVTEYLEHNFFRIKPV
                     RTRSAKGIYEMKVKINKKNYRIAFALKKNHVFIFYISSNLQKIVFDKEVSKKIK"
     gene            complement(396..830)
                     /locus_tag="PB779_002012"
     CDS             complement(396..830)
                     /locus_tag="PB779_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739530.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1062..1772)
                     /locus_tag="PB779_002013"
     CDS             complement(1062..1772)
                     /locus_tag="PB779_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDE0739531.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(1762..2622)
                     /locus_tag="PB779_002014"
     CDS             complement(1762..2622)
                     /locus_tag="PB779_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HDE0739532.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(2627..3265)
                     /locus_tag="PB779_002015"
     CDS             complement(2627..3265)
                     /locus_tag="PB779_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HDE0739533.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3280..3579)
                     /locus_tag="PB779_002016"
     CDS             complement(3280..3579)
                     /locus_tag="PB779_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739534.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(3622..5106)
                     /locus_tag="PB779_002017"
     CDS             complement(3622..5106)
                     /locus_tag="PB779_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HDE0739535.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5126..5587)
                     /locus_tag="PB779_002018"
     CDS             complement(5126..5587)
                     /locus_tag="PB779_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0739536.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(5605..6672)
                     /gene="ulaG"
                     /locus_tag="PB779_002019"
     CDS             complement(5605..6672)
                     /gene="ulaG"
                     /locus_tag="PB779_002019"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HDE0739537.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            6890..7660
                     /locus_tag="PB779_002020"
     CDS             6890..7660
                     /locus_tag="PB779_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HDE0739538.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(7933..8760)
                     /locus_tag="PB779_002021"
     CDS             complement(7933..8760)
                     /locus_tag="PB779_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0739539.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9328..10563
                     /locus_tag="PB779_002022"
     CDS             9328..10563
                     /locus_tag="PB779_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDE0739540.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(11562..11822)
                     /locus_tag="PB779_002023"
     CDS             complement(11562..11822)
                     /locus_tag="PB779_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HDE0739541.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(11849..13150)
                     /locus_tag="PB779_002024"
     CDS             complement(11849..13150)
                     /locus_tag="PB779_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739542.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(13442..13900)
                     /locus_tag="PB779_002025"
     CDS             complement(13442..13900)
                     /locus_tag="PB779_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0739543.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(13913..15244)
                     /locus_tag="PB779_002026"
     CDS             complement(13913..15244)
                     /locus_tag="PB779_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HDE0739544.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGCDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15255..16697)
                     /locus_tag="PB779_002027"
     CDS             complement(15255..16697)
                     /locus_tag="PB779_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0739545.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLAGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(16684..17448)
                     /locus_tag="PB779_002028"
     CDS             complement(16684..17448)
                     /locus_tag="PB779_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HDE0739546.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(17552..18427)
                     /locus_tag="PB779_002029"
     CDS             complement(17552..18427)
                     /locus_tag="PB779_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDE0739547.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLIDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
BASE COUNT         5847 a         3875 c         2850 g         6022 t
ORIGIN      
        1 tggattatac tgttgaattt gacagtgaac tacttaagca atttccacaa gaagaacatt
       61 tcatgtataa agaagcaatt tcccacaaag tgacagagta tttggagcat aatttttttc
      121 gtataaagcc agtgcgtact cgttcggcaa aaggaatata cgagatgaaa gtcaaaatta
      181 ataaaaaaaa ttatcgcata gcatttgctt taaaaaaaaa tcatgtgttc attttttata
      241 ttagttcgaa tttgcaaaaa attgtatttg ataaagaggt gagtaaaaaa ataaaatagc
      301 tgagcattgg aggatagatt gagtgatact aagtctatcc tcttgttttt ctaaagaact
      361 aagctagaat tttttctttt gtacgttatt atatgttatt tgtcattacc aaaaagcacc
      421 ttttttcttc tagtatctat gacataagaa ataccaccca tttcctttac ttgaacaaat
      481 cctactgatt cataaaattt ttttgttttc tcagtatcat ctgtcaataa ttcgatttgg
      541 actggtccat aactagtgat cttctccaaa gcttcattca aaagcacttt gcctattcct
      601 tggcgctgat acctcggatg aatgaggata tcttgaataa atgcgatcgt cgcaaaatca
      661 gtgatccaac gaacgattcc gataatcttc ccttccccat tacgctttat cagagattca
      721 gattgttcaa atgctctagc taaccttgca gtgtcttttg tgtaattcgt ccaaccaacg
      781 ctcttatata attcagaaat ctcatcgatc ataagggaat caatattcat ttttttcttc
      841 ctttcttata caattctccc tctaataata cagttctttg actatttaat ctatcacata
      901 taactctcct gtaaagattc tctcgattcc ttaaaattcc tctttccttt tagaatgcat
      961 actttttgat aaataaaaag gttgtgataa attttcttca caacctctgt ttctctctat
     1021 caagtgttat cttttaattt tctaccctta ccctagcatc tctattgccc gtagtatgca
     1081 tactttccat gtttgcgaaa ataatgttta tctagtaaat attgcgggat ttcacatata
     1141 ttggggttga tcagctcgtt ttctttggcc atcagacaaa tttcatctaa gatcaaactg
     1201 ttttctactg ctttcatagg tgaatccccc catgtgaacg gtccatgtcc atagacaagt
     1261 actccaggga cttcgtttgg atctaatttt ctttccttaa acgtctcgac aatcacattc
     1321 cctgtatgaa cttcgtaagc ttctcttact tcttctttcg ttaattggcg tgtacaagga
     1381 accttaccat aaaaagcatc agcatgagtc gtgccataag ctggcaaatc gcgtcctgct
     1441 tgcgcccaca tgacggagtg cgtggaatga gtatgagtaa tagcagttat atcttcaaaa
     1501 gtttgataca aaacaacatg tgtggggaga tctgaagatg gttttaagct atcttcttct
     1561 attatatttc ccgacaaatc tgttaccacc atttgatctg cttgcatgca ttcatatctg
     1621 acaccgcttg gcttaatgac gatgactcct agctcacggt ccacttcact cacattgccc
     1681 caagtcaatt tgactaatcc gtatcgcggc aatgccagat ttgcttcaag gacacgttgc
     1741 ttcattgctg caattttttc ttcacaagac atcatagcca gcctccttca atttagaact
     1801 taagtagtct tttgcctgct ggatttctct tcgaaagtct tggctttttt cactccacat
     1861 ttcaatcaga aatgttccat cataatctag acgtttcaaa tgtcttaata atccaagaaa
     1921 atcaacacaa ccgctaccaa aaggaacatc acgaaactgg cctgaatatt cttttgttac
     1981 agggtaagta tcttttaagt ggatagcagt gatataatcg atccctttct caagttctcg
     2041 agccggatta ttttccggcc atgcggacaa attgcctagg tctggatata cttgtagaaa
     2101 aggtgaatga atctgttctt tgatttctaa aaattttgaa atggagttca taaatggatc
     2161 atccatgatt tccacggaaa gaatgatgcc atatttagaa gcttccttta cgctttcttt
     2221 tattccttcg ataaagtctt ctctggaatt cattgatttc tcttcataat aaacatcgta
     2281 tccagctatt tggattactt tgacgcttag attatgcgcc aaatggattg cttttttcat
     2341 tagttgtttc gctgcttttt tcttttctgg atcagcagaa ccaaacggaa atcgccgatg
     2401 cgcacttaaa caaatcgaat ggatacgtac accggagctg aacatctctt ctctcagctc
     2461 agctatcttt tcttcagacc aatctaatcg tgctaaccgc tcatccgtct catcaatcga
     2521 catctcgata aaatcgaagt ccatttcttt tacaagggaa aaacgttctt tccatgaaat
     2581 atctttgggt aacgcttttt cataaatccc aatttgagcc atttccttac ccccagatac
     2641 gaatgatctc atctttgaag ttttgtgcgg ccttcatcgg atcatttgct gctgtaatac
     2701 cacgaccagt gataaaggta tacacatcga tcccttcaaa taagtgtaat gtgtgtggat
     2761 ttaatccacc agttacagaa acattaaagc ctagttcaat cagttttttg atcttcgata
     2821 aatctttttc accccaagtt tcaccagata acagcgcatc acggctttga tggtagatta
     2881 cctgccggat accgatgtta tgccaatcca tggcttgttc aaaagtccaa ttgccgtaga
     2941 gttctacttg caattcacct atttcttttt gtgctgcctc catagttgga atcgttgcac
     3001 aacaaatgac tgtcatccag tctgctcctg cttttgcaac attactcgcc actgttcctc
     3061 cagcgtctgc acatttcgta tcagcgacta gttttttatc tgggaacata ctgcgaatac
     3121 agcgaatcgc tttttgtcct tcctgtaagc aaagaattgt gcccacttca ataatatcta
     3181 ctacatcacc aactttcata acatctccta atgcatgttc taagtcattg tgatctaacg
     3241 caatttgcaa attcggcctg ctcatcttag ttccttcctt tacttgtttt tttggtacca
     3301 ctttgtttca gcaaattttt cactgatttc tttgactgac atcacatttt tgataccgat
     3361 aactgtaact ccttttttct ctgcctgagt aaacatattc aaaaaattga ctggcgtaaa
     3421 aactacatcg tattggccag ctgaactttt tccctctgaa atggcacaat gatggatttt
     3481 ggtaattggt acgtttagtt ctttcattgc tttttccaca cttctcatca tcatcaagct
     3541 tgttcctgat ccatttgcac acgatactaa aattctcatc ttaatccctc cattatgagt
     3601 gttgtctaat cagattttct tttatactct ctgcttttct gcatatgtgt catagtcttc
     3661 tacaatcaaa aaataaccat caggattttt ccgatattgt aactgcggaa tagccaataa
     3721 accaatgaca actacggcaa ttccagcata acctaggact ttcatgatta ctgtaaacaa
     3781 tggccaagct gttgcccagt cgaacatccc gatataacca ccgtatgttg acatcccaat
     3841 ccatgtagcg aataatgctg aaccgcctac ttgtatgatt cctgaaagaa acgggaacag
     3901 gcaagcggct ttgaatccac ctcggttatt ggcataaact gctataacgg cattatcaaa
     3961 gaacaacgga atgaaaccgg ctatgacgat cgttggtgat ttcaataaaa tcagtaaacc
     4021 aatcatcaaa aactgtccca aagcaccaaa caagaaccca atcgttaccg catttggcga
     4081 accaaagcca aaagtagcag ctacgtcaat tcctggaaca gctcctggta aaatcgtgtt
     4141 tgagattcct tggaaagatt gagttagttc atcgacgaat gtccgaacac ctaattgcaa
     4201 gatcgccaga tataccgcaa aatttaaaga agtcgtcata atgtagaata agaaactctg
     4261 cccttcttgc atgaattgcg cttgaatcaa ataatctttg cctagtacaa tcagaatgat
     4321 cccaaagaaa aatagcatga gtaacgaagt agcaaccata ttctcattga aaatcgacaa
     4381 gaatcctggt aatttgatat cttcaatttt tttgtcttgc ttgattgatc tatttttctt
     4441 ttcatcccgc tttttcatcc actcagctaa ttttgcaaat ataaagattc cgaacatttg
     4501 ctgatgtgcc actgcaaatc cggcaccttc tgtcaattcc tgcgtgattc ctactgttaa
     4561 gttagaagct actgtccaat aacaacctaa aatcagtccc ataaaaatca atgcttgtat
     4621 cctacctaga tcaggaaagc aaaacagtaa aatccaaaaa gcggtagctg cttgttgaac
     4681 ctgaacgttt ccggtagtga aaacggaacg cagtttcgta tatttctgaa aacggactaa
     4741 taagatattt aaaacaaatg caatcagtaa taaaatcatc acatctccaa aggtacggcc
     4801 aaatgtctcc attaatccag catccacagc attttgtcca aaataaggat ctgtaaccat
     4861 ggcatccaaa ttgaaccgtt cctttagtcc aaccaagatt ggccgaaaat tattgaccaa
     4921 accaccagag ccaacagtca aaataaagta accgaccgtt gcctttaaga atccagcgat
     4981 gcattcatga agcgggcgtt tcagcaaaat atagcctaat aacacgataa aaccaatcag
     5041 gtatgctggc tgcgtcaaga tatttgttgc aaaatacgtc caaatgctta acaaaaattc
     5101 ccccatcttt tttctcctct atcaattaat tatattctgc catcacaact tggtaatcat
     5161 cgatggagtt cgtagagatg agacgctcaa ccaatccatc tgtcattaat aattcggata
     5221 atttttggat attttctaga tgttcttctg gatcttttgc tgcgagtgta aaaaacaaac
     5281 tagccgtttt ctcctcattc tccccttcac tttcaaaacg gattggctgt ttcaacttgg
     5341 taaatgaaat agctgttcca aaaacaccat cacttttttc tgaagaatgc ggcattgcta
     5401 cttgaggtgc gatcacaata taaggaccgt atttttctac acaatggatg atctcctcca
     5461 catacgtttc atcaataatt tccttatcga tcaatacaag acagctttcg gcgatagctt
     5521 cacgccaatc cgtgatttct ttatctgggt aatgaatcaa ttgatggtca aaaaagtatt
     5581 tcagcaagaa actccccttc tttcttataa aaacgacgga aacggtgtat cattttcaat
     5641 cgagaagaca tcttcaaatc ctcgataaaa attaaactca agatcatctt tgtttgtcgg
     5701 atagatgaat ttcccgccta cttgccagat ataaggttta aatccatact tcaggcgatc
     5761 ctttttgaat ttccaaattt cagtgatctc ttttggatca gccataaaat tagaccaaat
     5821 atcgtagtgg acaggaatca ctacttttgc attcaatgac tccgccatgc gcagcatatc
     5881 aacagaagta actttgtctg ttatccctcg tgggttttca ccataggccc ctaaacagac
     5941 atcgattttg tgttcattac catgtttggc aaataaattg gagtaatgtg aatctcctgc
     6001 atgataaaga ttccctcctg atgtttcgaa taaatagttt actgcaattt gatccatctc
     6061 ctgaggcatt tttcctttta atacctcttc tggatcttca caagtgacca acgctgtccg
     6121 atcaaacgct tctaaagcta ctacattgat gtctttgatt ttgactgcat cacctggctt
     6181 tactgtaatc gttttttctt caggaattcc ccatttttgc cacgtgcgaa ccacttcttt
     6241 tggcccaatg aatgttgctt caggacaatt ttgatgaact gctgcggctg tatggatatc
     6301 tagatgatcg gaatggatat gtgtaacgat taaagcgtct acatttttta tcgcaaaagg
     6361 atcgattacg aaaggctgag tacgtaaatt aggctgcata ttttgaacgc cactcatacg
     6421 catcatctga tggccttttt tcatcatgcc attcccatga ctacgttttc ccgtcccaca
     6481 ccatagatca cataaaatat tcgttccttc atgacttttc agccaaattc ccgtacagcc
     6541 cagccaccac atagcaaaag ttccaggatc cactacttct gtttcgattt cttcattcaa
     6601 gtatgtgccc cactcaggaa atgtttctac taaccacttt tcttttgtta cttcattgac
     6661 agttttactc atttgcttgc tccccccata tcgttgttcc aacttacaag taaatattaa
     6721 tgtgtatcag catccatgaa aaccctttta tatgaccgtt tgttttttat atgattttct
     6781 ttcagtaatc aatgattgtt tcagtataat aaagacagat atgaatgttt aaatgaacaa
     6841 ctagtcaaat aaatccatgg atcaagatgt ccctcaggag gcaaaagtca tgaaaaactc
     6901 acttgtcaat attgaaaaac gtcaaaaaga aattttggaa ctgcttcagc agactgaaca
     6961 actatcaact ttcgaattag ctgaatccct tgatgtatct attagtacga tacgaagaga
     7021 tttaaattta ttagaagaaa aaaacgagat catacgcaat tacggttatt gttcttataa
     7081 ttacaaaaac cagactgatt ttgatcaatc tggtcctgaa aggattaaac aagcgattgc
     7141 cagagaagct agtaaataca ttaacgatta tgatacgctg tttatcaatt ctagctcgac
     7201 tgcgttgaaa acactggatt ttcttcaatc taaccatttg acagtcatta caaacaacgt
     7261 gaaaatcaat tactctccgc acaaagataa ttgtagttat attttaactg gtggagagat
     7321 gcgctttcca aaagaagcac tagtgggcga catcgcatta aatacgattt cttcagtcaa
     7381 tgcagacatt tgtatcattg gctgtagcgg agtcgatgta gtacatgggg tcacaacaaa
     7441 gatattaaat gaatcaacga tcaacgaaat gatggtcaac aagacaatca aatgtaagat
     7501 tttagtcgct gatcatcgaa aaatcggact gacatcaaag ttcaagattg ctgatatttc
     7561 agtctttgat tatttgatca ctgataaatt ttgttctgaa aaagtattag aggagatcag
     7621 aaatacgggg ataaaaacca ttcaagtaga ttcattttaa gaaccaggac gtaaatatgt
     7681 aaataggatt atcaaaaaaa tgaataacaa atttatcgat aaatgaaaaa cacgctacgc
     7741 tcaaattgat aaaggaatcc caagatgtat ccatccaatc gataccatca taatctattg
     7801 cttcttttat aaccgttata tgttgcctaa ataggaatca aacaatatcg aaaaaaggag
     7861 gtatgacaaa agtcacacct ccttttttcg aataaacggt attcaaatca gaacactgat
     7921 ttcacaacca ctttatttca ggtcgttttc aatcaccttt accgcgtaat catttccgtt
     7981 gaaacgcgct attttttttg cgtccatata tctttctaaa taatcatctt ctcctaattg
     8041 cttatggcaa gaagcaattt cataaagcaa gtattccaat gcataagtcg atttatgttt
     8101 cttattatac tcaataccct tctcacataa ttggattgct ttatcataat cctcgatttt
     8161 acggtaatag gtggcgatat cataatatac aatgcagacc atcagattat caaaatcagt
     8221 ctcactcaat attttaagtg tacgctccac ataaactttc gcaaaatcta attctccttt
     8281 tgacaagtag atcattgcca cgtttgcagc tgcttgtaag tgatggatat ctgtttcggt
     8341 cgtttgttcc aacacttgat taaaataaaa taatgctgca tctggttttt tcgcataaag
     8401 atgatcaagc agtccttgat aaaataaaat ttgatttaaa agatcagaat tacttacttt
     8461 ttcctgatcg atcgtttgta aaattttata agattcttgg tattttgata cagaattcaa
     8521 tgattgaatc tcatttattt ttttcctgat tttgtcttct tctgtttcta ctaatatatc
     8581 ggagatctcg acattcagct ttttgcaaag cgcacttaag atattgatgc ctggcgacat
     8641 attcttgttt tcgatattgc tgacagttgc ttgttcacaa atgccttctg ctaattgtac
     8701 ttgtgttaac ccctttttct ttcggtattc ttttagtaat gctccatcta ctttaatcaa
     8761 aacaatttcc ttccctttaa aaaattattt ctcctttata tcatacacaa aaaaaagttc
     8821 taaacaacca aaaatgttta gaacagaata aaaattttaa ttttaaaata atattcaaat
     8881 taaacaactg gcgtatctgc tccttgattt ctttttgtgt tatctgaata attatcgttt
     8941 acagttataa cacatagtga aaattgtcat ggcgagaaag tctaagaata tttttaaaca
     9001 taactatttc tttcttacgt gtgtataatg acgacagcac acctatcaat taatataatt
     9061 attttatttt tttatgttct catgtttatt tttaatgaca caacttctcg tatttatctg
     9121 gcacaacata taaatcgatc aaaaaattgt tgcgtgtttt tttgaaaatt ggagtttcaa
     9181 cttgattaca aaatttaaat ttagaagttg tgaaaacagc gagagacagt ttaatattca
     9241 aaatatacat aggctactcg aacgctgtgt tttttagtat actagtaaga aacgaaggga
     9301 tagactcatt ccaataagga ggatttcatg aagacaattc tttttgctcc tgcagtattc
     9361 aatttagctg agacaacacg aatgattgag gttgccaaag ctatgaaaga ccgttattac
     9421 tgtgtattct ttggcttttc taaaactttt gctcctttga tcacagaaag tggctttgag
     9481 tatcatttac tagcgccgat ccttacgaaa aaacaagaag aacaaatcat aaaatttgac
     9541 cagttgcgta cacttaaaaa cccttttacc aaagaaatgg ttgcctctcg tatcactagt
     9601 gaacagagtc tgattgctaa gtttgagcct cgactgattg tgacaggttc gaatgtgaca
     9661 atttttttat cggcccgcaa taaaaagatt cctttagtat atgttaaacc ctatgctttg
     9721 agtgaacctt tttttcaatc agagcatgcg ctgatgcccc acgagttacg tttcttcggc
     9781 cctttaagca atcccctttg gcactggaca aaaaagcgta tagtaaatac ccgatggatc
     9841 cccaatgcct tcaaacacgc tgcacaaaaa gaaatgcttc ctttaccaaa aacaagttta
     9901 caaatgatgg atgctgatct aaatctcatc acaacgccta aactattttt ggaagaagaa
     9961 cagctgccgg aaaattatcg aatcgttggt ccaatttttg ctaagctcag tacttccttg
    10021 cctgaagaag tgctaacttt tatacagcga aagcaacaag aaagaaaacg tattatctat
    10081 ttcgcaatgg gtagttcagg caatccgcgt atgttacgca aaattttgtt cttcttacaa
    10141 aaacaaccgg atctagcggt tattgcacct attgactatc tgcttgatga cattcaatct
    10201 gactcagaag atcttttaat aacagaatat ctgtctagtc atcttttgca tgaattcatt
    10261 gatttttctt ttatccacgg cggggaaggg accgtccaaa ctgcctgtga atccggcaaa
    10321 ccgtttatcg gtgtggggat gcaatttgag caaagctgta atattgacta ttgtgtaaaa
    10381 tacggaaacg caatcgccct cacaaaacca gtgactgaaa gaaaactgca gattgctctg
    10441 cgcgaagttt cttcacccaa gattcgtcag caggcacgca cgctgcaagc cgtttttcca
    10501 ataaatggtc cacaacaagc aattcaagaa atcgaaacct tcctgagcaa ccacccaata
    10561 tagtttcaag tagaaaaagc ttttttaata gagactcatc agtaatttcg ctattcgaga
    10621 cccagacagt gaaaatacaa aaaaagtaaa tagtggattg aaaagttaga gttacttaaa
    10681 ttacggtgtc taaaaaacac aaaatcatcc ttaaaataaa agatctgacg ctatccaaat
    10741 gagcataggt agcgtctgcc atttattctt agtcaaattc tttgacacct ttctctggtt
    10801 ggatcatctc aacgtttctt caaaagaaag accataataa ttaggcaaat acattttctt
    10861 aaaatgtgtc atatagatct agaagcatcg ctttgtagag atttgtgccg ctagtcccct
    10921 caacaattac taaatcaaat gtaggattta ccactttatc tttgataatc aacctccctc
    10981 ttctgttgag acaatgatct cgcaatccga tgcatactcc tatataaact gccagcaatc
    11041 cccacatatt gagtagatca tgtcagaatg ttctatgtcg tcagcaacga tacactaaaa
    11101 gtcacgttca ccatgactga ttgctattcc cagcacaatt atttctatac acgtttcatg
    11161 atttgaataa acactcacat catacatatt accattcata caccatactg cagcccctac
    11221 tatatggttg taagctccca aatctatatt tgacttgatc actttggtag tagatctact
    11281 aattctaaat ccattgctga taaaatttcc attttttcct ccttctttct gccaaaacag
    11341 ttaaaacaat aataatcttt atgtaaaaaa gggctgtgac aaaagccttg tcacagtccc
    11401 atattccgaa taaacggtgg tcaaaagctt gcatctgcgg taataagttc aaccaaacga
    11461 aaaataagcc aacatttcac aaaaatttaa gaagcaattt tcgtaaattt cttcttattt
    11521 cttgaagcta accacttctg ttacaaccac ttttagaaca tttaaagctt cgatgtgaca
    11581 aaccatctat gctgctcgat cataaaattg atagcaaaaa ttccacaaag tacatatgtc
    11641 ccccatgaaa acaaaacatt catatgcggt acaatgatct ttggaagaat cacgatcaaa
    11701 aatgatgcca gtgcccaaat ccatcgattg atttgaatat gatatgtagc tagcatattc
    11761 aatataaggt gactagccgt taataaaaag ataaaaacaa aaaataaaat cagccaatac
    11821 attgtttccc accttctaaa aaccaaactt agacagtctg gacttcgttt tctccacgac
    11881 tttgttcatc tgacagcatc tttttatcat aagcttttac aaatggataa tagataataa
    11941 atgctatcaa tgtgttgatc atgatcaaga taacaacacg ccagtcattt cctgctgaaa
    12001 gataaccgcc gattggagct ggtaatgtcc atgttggcaa aacagtaaat ctattgacca
    12061 tttctaattt gactgcaaaa taactgataa tagtcaaaac taaaggaact aagttgaacg
    12121 ggatgaacat gtaaggattc aacatcatag gagctccaaa aattatgggc tcattgatat
    12181 tgaagatacc aggaataata gaaaaacgac caacctcttt caagaatttt gatttacaga
    12241 agaatataaa caaaacagat accacgatcg ttgctcctgc accaccaatt gttaccgtcc
    12301 attgataaaa ctgttcagga gcgatatagg gtaattgggt ggcagctgta ccatctgcca
    12361 atgcctttgc attctcatcc aacatgatca gccacattgg acgaacaaca gcccctacaa
    12421 tactcatgcc atggatacca aatgaccaca acaaatggat caaaaacatt ggtagtaaaa
    12481 caccaagcaa attattccct aaaatattgg ttaaaggctc gaataacgat aataaggcag
    12541 cgtttacatc aaagcccgcg acgcttcgaa tcagccaagt aattgttaaa atgactgcac
    12601 ctggaatcaa tgcctcaaaa ctacgggcaa cagcaggtgg cacttgttct ggcattttga
    12661 tagtaatatt tcgattttta aagaaacgat atacttccac tgcaaaaatc atagataaga
    12721 tccccgcaaa catcccagat gctcccaaag aactcatagg taagacccag ccaagaggtg
    12781 cctcttcagg agttaaaacg tttacaggaa cttgtaacat aaagaacgtt cctaaagata
    12841 atataccacc tgtcacacta tctaatccat atgatttagc tagatccgaa cccataacaa
    12901 aagttgcata aatagccatc aatcccatcg tcatcctaaa gggtaaaaca atcgttgccg
    12961 aataaggggc aataaattca ttccatccag gaaacggtaa attgataaag accataaaaa
    13021 atgtcccaat caaaatcaat gacaatgttg aaacaacccc attacgaatt gctaataaat
    13081 gacgctgtgt accaattttt gccattggtg ggacaagttt ctcttcgacc catttcatca
    13141 gcttttccac taaaaccact ccttttcaat aaaatatgaa ccattcattg catgacaacg
    13201 caaagaatgt tcataactaa ttatataatt aagaaatttt atttcaatat attctcttaa
    13261 ataatcaaat ttatttttaa gaatcctgaa aataagtttt ctaaatcata ggagcaacaa
    13321 aaaaattcga taattaacaa aaatcaaaat gattaaatct agtgattgaa acatatcatt
    13381 tcaaaaaaat tttgtaaatt cacccataaa tatcacccta tttaactttt ttcatcgtac
    13441 actaaaattc aaaacaacta tctttaatct ttacttcttg gttttgtttt aataaatttc
    13501 cttcaaaaat gcctggagaa actacaatga tcaccgtatc tttttgtgct tgctccaact
    13561 tcttcaaatc tataatagct aacagtgtcc cttcttttac ctcctggtta ctttcaaccc
    13621 gtatctgaaa cggacttcct tcgagttcaa ctgtatctaa acccatatgg atcagtattt
    13681 ttctgccaga ttcactttcg atcgttatgg catgtcgggt aggaaatata ttatcgatta
    13741 ttcctttaac tggcgcatgg atatatccat catgattcgt tatagcgtat ccaactccta
    13801 tcatttttga agaaaagacc tcgtctttta ctgctgttaa tggaataatt tgaccactag
    13861 ctacagcttt tagaatgttt cttgttttaa agaaatgcac tttttatcac ctctacttta
    13921 atgctggcca atattttttg tttactttga tcatttcatc tagtattttt tttgcgactc
    13981 tggcatttgg tacggtttga ttcaatgtaa atgcttgtaa agctttttga taagaacctt
    14041 caaagtaagc atctactagt aacttctcta ctgcaacttg tgcctccatc aatcctttat
    14101 gaaaatcact gattggtttt cttagtgtaa ttggctccac accagttgca ccaacatatg
    14161 ccggtatttc aacaactgca tctgaccgta gattcggaat cgccccttga ttaggaacga
    14221 ttagcataaa gcgacgacga tcatcattca acaaggaaat agctatatcg acgatatatt
    14281 gtccatgctc cccaaaatta aagttcaata cttcttccac aataccgcgg cgtattttat
    14341 cagccatttc tttggtattt ttctctcgtc catccatgac catattagca cgtgtatact
    14401 ctttgtcagt atgctcaacg accatatcag gatataagta atactctaag taattattcg
    14461 ggatattact tggaaaattt ttcgtgatga ctgacatcat ttgaaaggtt ttttgccaag
    14521 ttttatctcc tatattaaaa tcggcgactt gcatttcttt tgttattagt ttttcaataa
    14581 tctctggcat aatttctcgt tgcaattctt tatcataaat cgatgtatac cagccaaagt
    14641 ggtttaaacc ataatacgta acgatccaat tcttacgatc ataaccgtaa ttcactgcaa
    14701 tcgtttcttc aattgaaata gtcatatcac aggcattaat catttttaca ttcggatatt
    14761 tacgacgaac agcttcagaa acgatcgact ctggatttgt ataattcaaa atccatgctt
    14821 tgggggcata gtcttgtata tgatcgacaa tttccaataa acctttgatt gagcgcatcc
    14881 cataagcaaa tcctccgagt ccacacgttt cttgtcctac taatccatgt ttaagtggaa
    14941 tcttttcgtc cttttctcgc atctccaatc ctccaacacg aatttgtgag aaaacaaaat
    15001 cgcatcctgt aaaagcaagc tttggatcat ccgttgcacg aatgcgaata tttgaaaaac
    15061 cttttctttt cagcataaat ttaacaatca agtacatatc catatttctt tcttcatcaa
    15121 tatcatataa acgtatttca gataatggca accgtttttc attgttcaaa atggcttgaa
    15181 cgattcctgg tgtatacgta ctcccgcctc cagctatagt gataatctgt tttttcatca
    15241 tcatcttttc ctttctattc ttctaataat ttattgaatt ctgccataac ataagtcact
    15301 tctaagccga tgataatttg ataatttttt tcagttggtt taatgatccc gcttatccct
    15361 aattgcttga ttcgctgttc ctcgaccatg gtgggatcca ctacctctac ccgtaggcgt
    15421 gtattacaac tatagacatc caggatattg gcttttcctc caaacgcttg tagcattttt
    15481 gttgccatat attcataatt tttacttgct aaccctaact ctgtttcttc taaggttact
    15541 tcattgccaa actctgcctt agcttcacgt cctaatgtct gaatgtttct cttattgatc
    15601 aaataataaa aagtaacgta atacaaggca aaaaagaaaa ttccgattgg aagaatcaaa
    15661 atagcattgg tagcgattcg aaaattgatg agataatcaa caatacatgc tccgaatgta
    15721 aaaccaattc gtatattgaa taagtaacag acaatccctg ctaaaccggc aaaaagtgca
    15781 tggatcacgt acaacatagg agaaagaaac atgaaactaa attcaacagg ctcagtgata
    15841 tttgcaataa atgaagttcc tgcaccgctt cccatgattc ctttgaccat ctctttattt
    15901 tctttataag ctgctttata gatagctaga catatagctg gtataccaaa catcattact
    15961 acaaaaaaaa ctgataaaaa cagtccagcc tgaggatctc cgttgataaa gcgtgtcatc
    16021 tctcctctga aaacttcctt gctaggagat gtatagcttc ctaaatcgta ataaatatac
    16081 gtattcaaca catggtgcag tccaaagggg atcagcaaac gattcaaaaa cataaatatc
    16141 cccacaccta atgctcccat atcaacgagc agttttgcaa aattatcaat cccaatttgg
    16201 atgagcggcc agataaagcc caaaaaaaca gctgcgattg tttgtagaat catcaccata
    16261 gtcaatggga atttttcgcc cgcaaaataa gaaaaaacta ctggtaattt ttgttcttta
    16321 aagcgattat acgtccatgc cgctactaaa ccggaaataa ttccaccaaa aatccccata
    16381 ttcacttctg ggtccataat ttctaagcct tttttcaagg tagcaatcgc taaaaaacca
    16441 gtaagtgcag gtattccttt gtccttattt ttgacaaaac cgattgcaac tcctatagca
    16501 aataagatat ccaagtttcc aaaaacggca tttccagctg caccaattac tgggatgttc
    16561 agcatatcgt cagctgataa acgcatgatc aatcccgcta atggcatcgc tgcaactgga
    16621 agtagcatcg ctcttccaag cttctgcaca tttgatttaa cattcatttt tattcctcct
    16681 ctattaaata tcctcatatg ttactaactc aatcaaagga tcatttttca ctttttgagc
    16741 aaatgctgaa tgaattaaaa attcgacttg gtgggtacga ggatacacaa aacttgaacc
    16801 atttaacaat tcctgatcca aatacgctgc gtgacacatg acttcgatcg ttttatcttc
    16861 tctcaatatc atgagtaaac ttgccaaata ttcttccaca ctcgtattga tttgtcgttt
    16921 tttttcatca gtttctccta cgacatcgaa acaaggctca aaataatcga catgacgaac
    16981 ttcatctttt cgttcaaagt tgctccgaac cggcaaatca tatttttttg ctaatgtaac
    17041 aactacctcc tgattttcat ccaaagtatg agtatgatga tgactgtcta aatgagttgg
    17101 tatgatcccc gcatgataaa ttttttgaat ctgagcattc cattcctgat acagttgatc
    17161 tttgtcaatg ttaaatggat gctgataata agataaggat ctgaactctc cgctttcgat
    17221 aagagtatcg acagttttga ggagtggttt gccacacgtc aatgttaaat ggactcctac
    17281 acctagccta ggcatttcct ttcttagttt cacagcatgc tcgaaacccg gcatatttgc
    17341 catcaatgta gttgatgtca aaattcctcg ctgataagca tccataatcc cataattcac
    17401 accatggcta tagccaaaat catccgaatt aaaaatcact tttcccattt cattctcctt
    17461 cttttttcta ctaaaatagg cgcaaccaaa taatcatagt ccatttacta tgtgtcattt
    17521 ggttgcgcct atagatagtt acgcccttat tttaatagat tcttgctaga tgaattgcca
    17581 aatagatgat ttcattttct tgaatggcaa gttgaaattg ctgttcgatg atatctttaa
    17641 tctttagtgc tgtacaatac gctttgctat gtttaaatgt ttcagtaaaa aaaccaatat
    17701 tttctactgg cgtttcttcc tgataaatca agcgtttaac caggaatttg atatgaacca
    17761 ttaagcgatg ataagtcagt gattctttat cataaacgtt tgaataggat ttttctagat
    17821 gggacaaaat cgtggtcgtc atttctacta tttttaagct ctttaaacta ttaggctctc
    17881 ctagctcagc attaatgata tgcatagtga tgaatcctac ttcatttgac cctaactcgg
    17941 tttgatatcg atgattgatt cgctcgacca cttctactgc tatatcatat tcatttggat
    18001 aaaggaatct catttctggc aacataattg ctgtgacatc tctatcttct ctttttcgtt
    18061 gaatagcaaa ataaatatga tctgtcaatg taatatagat atttgaatct aatggagagg
    18121 agatcctagc tgttatcagt tcaatcactt cttccgcaaa atccataaat tcgattggaa
    18181 tctgcgagac tatctcactg aatcgtttga tcttttcttt agaatctaat acaaataatt
    18241 tgtcagcatc ctcaacatca aatggcttac tcactttagc agaaaagcca atccctttcc
    18301 ccatcgcaat tttttctatt ccatcgtcat cgatcaatac agcattatga ttcagctttt
    18361 tcatcacata caccgttaat tcacctcctc tatatgataa aacaaaacaa cttgcagact
    18421 ccttcataca tatttttgtc tccaaacaat ttttaaagac aaaaaacgac ctaagaaaga
    18481 accctttctt aggtcgtgcc taattgaata gtagcaccct acataattta caaaaatagt
    18541 ttaacacata ataaaagcgt tatcaatatc ttttttactc gttttatgat aata
//
LOCUS       DAMEEU010000058        17866 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.059, whole genome shotgun sequence.
ACCESSION   DAMEEU010000058 DAMEEU010000000
VERSION     DAMEEU010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17866
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.059"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            146..577
                     /gene="mraZ"
                     /locus_tag="PB779_002030"
     CDS             146..577
                     /gene="mraZ"
                     /locus_tag="PB779_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HDE0739548.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            598..1557
                     /gene="rsmH"
                     /locus_tag="PB779_002031"
     CDS             598..1557
                     /gene="rsmH"
                     /locus_tag="PB779_002031"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HDE0739549.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            1562..1963
                     /gene="ftsL"
                     /locus_tag="PB779_002032"
     CDS             1562..1963
                     /gene="ftsL"
                     /locus_tag="PB779_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HDE0739550.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            1964..4156
                     /locus_tag="PB779_002033"
     CDS             1964..4156
                     /locus_tag="PB779_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HDE0739551.1"
                     /translation="MSLKNKIRRFMEKKNLNPMNNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKNGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            4182..5144
                     /locus_tag="PB779_002034"
     CDS             4182..5144
                     /locus_tag="PB779_002034"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HDE0739552.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            5158..6519
                     /locus_tag="PB779_002035"
     CDS             5158..6519
                     /locus_tag="PB779_002035"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HDE0739553.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            6545..7633
                     /gene="murG"
                     /locus_tag="PB779_002036"
     CDS             6545..7633
                     /gene="murG"
                     /locus_tag="PB779_002036"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HDE0739554.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            7648..8868
                     /locus_tag="PB779_002037"
     CDS             7648..8868
                     /locus_tag="PB779_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HDE0739555.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            9024..10349
                     /gene="ftsA"
                     /locus_tag="PB779_002038"
     CDS             9024..10349
                     /gene="ftsA"
                     /locus_tag="PB779_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HDE0739556.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            10372..11613
                     /gene="ftsZ"
                     /locus_tag="PB779_002039"
     CDS             10372..11613
                     /gene="ftsZ"
                     /locus_tag="PB779_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HDE0739557.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            11630..12307
                     /locus_tag="PB779_002040"
     CDS             11630..12307
                     /locus_tag="PB779_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HDE0739558.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            12321..12920
                     /locus_tag="PB779_002041"
     CDS             12321..12920
                     /locus_tag="PB779_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HDE0739559.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            12935..13222
                     /locus_tag="PB779_002042"
     CDS             12935..13222
                     /locus_tag="PB779_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HDE0739560.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            13271..14053
                     /locus_tag="PB779_002043"
     CDS             13271..14053
                     /locus_tag="PB779_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HDE0739561.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            14074..14781
                     /locus_tag="PB779_002044"
     CDS             14074..14781
                     /locus_tag="PB779_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HDE0739562.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            15043..17841
                     /gene="ileS"
                     /locus_tag="PB779_002045"
     CDS             15043..17841
                     /gene="ileS"
                     /locus_tag="PB779_002045"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HDE0739563.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
BASE COUNT         6210 a         3025 c         3909 g         4722 t
ORIGIN      
        1 tcttttaaaa ggctttttgc agcttgattt ttaaaaaaat gtttatgaat aaaaaaagtt
       61 gttcccggat ttcccagaaa aggtggtaga aagtggggga ttgtggtaga ctaattttag
      121 ttagtggagg aatggggggc tttcaatgtt gatgggtgaa ttccaacata atattgatgc
      181 aaaaggacgt ttaatcgtgc cctcaaaact tcgtgaagaa cttggcgaaa agtttgttct
      241 gacacgcgga ttggatggct gtcttttcgg ctatccgatg agcgaatggg aaaatctgga
      301 agctaaactg aacgaaatgc cgttggctaa aaaagacgca cgtacttttg tgcgattctt
      361 ctattcggct gccactgaat gcgaacttga taaacaagga cgaatcaata tacccagcac
      421 gttaagaaat tatgcagctt tgacaaaagg ttgcgtagtc atcggtgtat ctaaccgaat
      481 tgaaatttgg gatgagacac gatggcaaga tttttctgca gcagcagaag agaactttga
      541 cgaaattgct gaaagtatga ttgatttcgg actataagaa taggaagagg ctgactaatg
      601 actgaaacat ttcaacacta tacagtcatg ttgaaagaaa cggtagatgg attgaacatc
      661 aaaccggatg gcgtttatgt agactgtaca ctcggcggtg ccggacatag tgaatattta
      721 ttaagccaac taagttctaa agggcatctg tatgcgtttg accaagatca aaaagcaatc
      781 gatcacgcca agctgcgttt agcttcttat gtcgaacaag gtatggtcac atttatcaaa
      841 gcgaacttca gagaattaga agaacgcttg agtgagcatg tagataaggt agacggcatt
      901 ttgtatgatc taggggtttc ctctcctcag ctagatgaag cagaacgtgg atttagttat
      961 catcaagatg caccgttgga tatgcgcatg gatcagtcag ctcctttatc cgcttatcac
     1021 gtaattaatg aatattccta ccatgaatta gtaaagattt tcttccgcta tggcgaggag
     1081 aaattttcca aacaaattgc tcgtgaaatc gaacgagtac gaaaaacaaa accaatccaa
     1141 acaactggtg agcttgtcga aatcattaaa caagtcatcc cagctcccgc aagaagaaaa
     1201 ggcgggcatc ctgcaaaaag aatttttcaa gctgtgcgga ttgcagtaaa tgacgaactc
     1261 ggtgccgaag aggcctcttt agaacaggca atccggttat tgaaagtcaa tggaagaatc
     1321 agcgtaatca cattccattc attggaagac agaattgtca aaagtatgtt taaagaatat
     1381 agtacggtac aagatctacc accgggactt cctgtcatac ctgacgaatt ccaaccagaa
     1441 ctgaaagtca ttactcgtaa accaatcctt ccttcagagg aagagctaac agaaaacaat
     1501 cgatcacgca gtgcaaagtt acgtattgca gaaaaaataa gaatgaaaga ggagtagaat
     1561 gatggcagaa ttaaagaaaa tgcaagatta cgaatatgat ttacctgaat tggtggatca
     1621 gccggaacaa caaatgcctg attcttcttc gaatcaagaa atcattcttc cacaatcacc
     1681 ggcaaaacga ttaaagcaga tttctgcttt ggaaaaaatt gctgtggcaa gcgtggcgat
     1741 tgctattgtt gctttatgtg ttttaacagt tatgctgcgc acaaatatca gcggagctga
     1801 aaaagaaatc acgtcaatac aaacagaaat caatgataaa aagcaagaaa aaacgagttt
     1861 agaacaagaa aaaaacgaac tttctcgtac tgaacggatt aaacaaatcg cagaagaaaa
     1921 aggattgtct attaatgacg acaatttaag gaaagtgaag taaatgagtc ttaaaaataa
     1981 aattcggcgg tttatggaaa agaaaaatct aaatccgatg aacaatcgca aaaaagtagg
     2041 tatcatttta tttgctacga gtattggatt gttcttttta tttgccgtcc gtttctcgta
     2101 tatcgttatt ggaggtcatg ttgctggtac ctcattagct gaaaaaacaa aacagttgta
     2161 ccaaggaagt gaagtagtaa aagcaaaaag aggaacgatt tatgatcgta acggtgtggc
     2221 gctcgcagaa gatgcctcct cttattcaat taaagcgata ctctcaaaaa catatacctc
     2281 tggggataaa aaactgtatg ttgaagaaaa gaattttgat aaaatagcag aaatcctgca
     2341 taagaatctt tctatagaca aaaaagatgc actgaatatt ttagaggacg gcgcaaaaaa
     2401 agagctgtat caagttgaat ttggtagcta tgggaaaaat atctcccaag aaaccaagca
     2461 aaacatcgaa gcggacatga aaaaagaagg tgtcgctggt ctttattttg tcgaccatca
     2521 ggctcggatg tatccaaatg gcgtcttttc ttctcatttt attggatacg cagttccaga
     2581 caaagatgag aatggcttag ttggtaaact aggtttggag tctgcttaca atgatatctt
     2641 gagcggtaaa gatggtaaga ttatttatca aaaagataat tttcaaaatc ctctgccagg
     2701 tacagtggca gaagaagaaa aagctgtcga cggacaagat atctacacga ctttagacag
     2761 cagactacaa agttatttag aaacactgat ggatcaagta aatgaagaat atcagccaga
     2821 agaattgaca gcagtcctga tgaaagcaaa aaccggagaa atcttggcaa tgggacaacg
     2881 acctactttc aatcctgaaa caatggaagg attgactgga aaagatgcta tctggcgtaa
     2941 tttcttggta caagatagtt atgaaccagg atcaaccatg aaagttttca ctactgcagc
     3001 tgctatcgaa gaaggagaat tcaacgagaa tgaaaccttc caatctggaa aaatccaagt
     3061 agaagatgct acgatcaatg accatgactt tggtgaaaaa ggtgtgctga ccatgcgtca
     3121 agctctttca tggtcaagta acgtcgggat ggtcatactg gaacagcgat taggcggacg
     3181 atggtataac tatttacaaa aactgggatt tggacaaagt actcattctg gattagatga
     3241 tgaagtaaac ggtgctttac ctacattaaa tattgtcgac cgagcaatga gtgcttatgg
     3301 acaagcggta ggtgtgacga atttccaaat gatgaaagct ttcacttcta ttgcgaataa
     3361 cggtacaatg attcaacctc gatatatcag caaagtggtg gatccccaaa ctggagaaga
     3421 gcgaacaact caaacagaag ttctagggca acctttttca aaagaaacaa cagaaaaagt
     3481 ccgtgaatat atgagagatg ttgtcgaaag cgaaaactac ggtagtgctt atggtgtata
     3541 tagtgtacct ggatacaatg tatcggcaaa aaacggaaca gcccaaatcg cttctgatac
     3601 agggggatat caaacaggag atacagccta cctgtattcg attgtggaga tggttccttc
     3661 tgaagatcca gactatgtct tgtatctaac aatgaaacac cctaagacat atgatcgaat
     3721 ggcattggct aaaatcgcaa atccattgat gaaacgggca atggatttta aagaaactga
     3781 agaagattca gatacagaaa caaaaacaga aaaagtatcc gtagccgatt atcgtaatct
     3841 tgaagcggac gttgcagcag ctgatgctca aaaaagtgga ctgcaacctg tagtgatcgg
     3901 taatggtaaa aaagtacaaa aacaatctac tgccaacggt gatcagttga tctctggaga
     3961 aaaactgatc ctatatactg gtggtgataa gctgatgcct gacgtaacag gatggtcaaa
     4021 agcagatatc atgaagctgg ggaaaatcct cggtattgaa gttagttttg atggagatgg
     4081 ttattgtgtc aaacaagaac ttgctccata tgaaaaaatc actgaagaca aacttagttt
     4141 tactttagaa gaataagaag agaaatagga gagaaaagag catggaatgg acacaagcat
     4201 tgattcccat tgtcagcagt tgtgcaatga caattgccgc aatgccgcta tttattggtt
     4261 attttcaaat gaaaaagcaa ggtcaggcga ttcgtgagga gggaccaaag tggcacaata
     4321 gcaaagccgg aactcctaca atgggcggct tagtgtttct gatcggctct attttgacag
     4381 gaatttgggt tggagcttgg caaaaacagc taactcctac tcttttcatc ttgctttttg
     4441 tattagcgtt atacggagta atcggctttc ttgatgattt tataaaaata ttcaagaaaa
     4501 gaaacatggg actgaactcg aagcagaaat tgattggaca gattctaggg ggaatcatct
     4561 tttatcttgt ttaccgttct gaaggttatc caggtgtatt gaatttcttc ggactagatc
     4621 tacctttagg aatcatttat ggtattttcg ctctcttctg gcttgttgga ttttcaaatg
     4681 cagtaaatct gacagatggc atcgatggat tagttgctgg cttaggaagt atctcttttg
     4741 cagcttacgg tctaattgct tggcatcagc atcagtatga tgtattaatc atttgcttaa
     4801 gtgttttagg aggtttactg ggtttcttcg tctacaacag aaaacctgcc aagattttta
     4861 tgggagatgt cggttcatta gcgttgggcg gacttttagc ggcaatttct ataatgctaa
     4921 accaagaatg gacattgctt ttgattggtt tgatctatgt tatggaaaca gcaagtgtga
     4981 tgcttcaagt tacttccttt aagcttacag gaaaacgaat ttttaaaatg tctccaattc
     5041 atcatcactt tgaaatgtgc ggatggtcgg agtggaagat tgatacagtt ttttggttga
     5101 tcagcattgt gacttcgttg atcacattat ggatcgtttg gtaggagatg acgggaaatg
     5161 aaaaaaatat caacatatga aaataagaaa gtgcttgtct taggactcgc aaaaagcgga
     5221 gtaagtgcgg ccaaattatt acatgaattg ggcgcacttg tcaccgttaa tgatggaaaa
     5281 ccttttgacg aaaatccgga agcacaagag ctgctttctt tagggataaa agtaataaca
     5341 ggtagtcatc caatcgaatt gttggatgaa gaattttcat tgatggtcaa aaatccaggg
     5401 attccctaca gtcatccttt agtagcaaaa gcccaagaaa tgggtattcc ggtaattacg
     5461 gaagttgagc tagcttacga agtagcggaa tgcccaatta ttgggattac aggaacgaac
     5521 ggaaaaacaa cgacaacaac gatgacagga ctactactga atgcaggagc agatcaagga
     5581 attgcacgtt tagcgggtaa tattgggtat ccagcaagtg gtgtagcgca agaagcaaaa
     5641 tcagaagata aaattgtgat ggaattgtct agcttccaac tcatgggaat cacagatttc
     5701 cgccctcata tagcggtgat taccaatatc tatgaagcac atattgatta tcatggtaca
     5761 agaaaagaat atgtcaaagc taaatggaac cttcaaaaaa acatgacaga aaaagattat
     5821 ctgatcctta actggaatca gtcagaacta caagaattag cgcaaagaac aaaagcacgc
     5881 gtactgcctt tctcgacaaa agaagtgttg gaagacggtg tgtatgctga cgattactca
     5941 atatactata aaaaagaaaa aataatggaa atatctgaac ttggcgtacc aggtaagcat
     6001 aatgtagaaa atgcactagc tgctatttct gtagcaaaat tgtatggtat atcaaatgaa
     6061 gctatacgag aaacgttgca ttttttccat ggcgtaccac atcgtacgca atatgtagga
     6121 gaaatccaag gcagaaaatt ttataatgat tcaaaagcaa ccaatatttt agcgactaaa
     6181 atggctctaa gtggatttga aacgtctaag gtcgtgttat tggctggcgg attagacaga
     6241 ggaaatacat ttgatgaatt aattccttca ttaaaaggaa tcaaagcaat ggtcgtattt
     6301 ggccaaacaa aagaaaagtt gatggatgct ggaaaaaaag caggcatcga gacaatagta
     6361 acagccgatt ctgtagaaca agcagttcct ttagcattag aaaacagtac agatggtgat
     6421 gtagttttat tatcaccagc gaatgccagc tgggatcaat acccaaattt tgaaactaga
     6481 ggaaacagat tcatggaagc tgtgaaccga ttaaaataga aaaagtagaa gcgagcgata
     6541 aaaaatgaaa attttggtta caggcggagg aacaggggga catatttatc cagctcttgc
     6601 ctttgtcaat tatgtaaaga ctcaagaacc gaatgctgaa ttcatgtatg tgggagcaaa
     6661 acgaggtcta gaaaacaaaa tcgtccctga tacaggaatg cctttccata ccttggagat
     6721 tcaaggattt aaacgaaaaa tttccatgca taacatcaag acggtccgat tgtttcttaa
     6781 gagtatccgt caagcaaaaa aaatcctcag tgattttcaa ccagatatcg ttatcggtac
     6841 tggaggatat gtttccggag cggtagtgta cgctgcagcc aaaatgggta ttccaacagt
     6901 tatccatgaa caaaacagtg taccaggtgt taccaataaa tttttaagcc gatatgtgga
     6961 tcggatcgct ctttcattta aagatgcggc ttcctttttt cctgaaaaca aagcagttct
     7021 tgtaggtaat cctcgagcac aagaagtagc agatactaaa aaatcagata ttttgaaaac
     7081 atttgatttg gatccagaaa agaaaacagt cttgattttt ggcggtagtc aaggagcact
     7141 taaaatcaat caagcagtat cagttttttt aagtgaatat attccttctt cttaccaagt
     7201 tttgtatgct tcaggagata gatattatga agagatccta aataaaataa atcctgaaat
     7261 acaaaatatt agtgtccagc cttatatcaa aaatatggca gaggtcatgg cttccagtga
     7321 tctgctggtg gggcgtgctg gtgcaacttc gatcgcagaa ttcacagctc tggggttacc
     7381 ggcagtgttg gttcccagcc catatgttac gaatgatcat cagactaaaa atgcaatgag
     7441 tcttgttcac gcaggagcag caaaaatgat tgcagataat gaactaacag gtgaatcact
     7501 aagtcagaca gtcaacgaaa tcatgggtga tgaagaattg caaaagcaaa tgtgccgagc
     7561 ttctaaagaa caaggaatcc ctgatgcttc aaaacgtctt tatgacttag taaaacaaat
     7621 aatcaaaaaa taaaggcggt ggtcttagtg agtaagaaaa aagaaccaaa aaaattgtct
     7681 catccgtctt ctgatgaaaa caatttgact ccttggcaaa aggctaaccg aaaatatctg
     7741 gcagaacaag agatgaaaaa ccaagagcca aaaaaagaag acataacatt agatacaccc
     7801 ctttcagatt ctgaagaaga aaaaacggtt caagaggaac agcaagaaga aagccagtcc
     7861 gagaaaaaaa tcgaattttt tgaagagatc aagcaaaaga aaaacggtgg accatataac
     7921 ggttcttttt tgaaccggct gcccaattta aaaagtcaac ggcacaaagt actatttcgt
     7981 cggttagctt tgatcatcac tgtattgggt ataccgctga tttttttgat ctattatgtt
     8041 tctccttata gcaaattaca agcagttgca gtatcaggca ataagacagt caacagccaa
     8101 gaaatcatct ctgatacaaa attgtcatta ggagaaaatg tttggggaca gtattttcat
     8161 cgatctactt atatcgatcg ccttaaaaaa gcacagccaa gaatcgaaac agcaaatata
     8221 catttcaaag ggatgaatga attcgatttg gatgtaacag aatataaaga gattgctttg
     8281 atcgcaaaaa acaatcaata ctacccagtg attgaaaatg gaacagtatt agatgaaaaa
     8341 gtagcaaatc ctacaaaaaa tctccctatc ttggaagagt tcaaagactc tgcaaaaatc
     8401 aaagaattaa caaagcaata caatcagtta tcatcagaat tacaaaaagc aatttctgaa
     8461 atcaagtaca cgccaagagc aagcaataaa aatctgatcc aattgaatat gaatgacggc
     8521 aatcaagtta ttgtaaatat caataatctt gcgaaccaaa tgaaatatta ttcgcaagta
     8581 gccaaagata tggatgaaaa aggtgtgatc gacatggaag ttggtatctt ctcgcatcct
     8641 tacggtagca ctcaagaaac ggaagaatcg ggccaatcgg aagaaacaac tgaaagtgaa
     8701 gaaaatgcgg atcaaacaaa cgaatcaagt gaagaggcag aaacgcaaaa agcacaaaca
     8761 cctggatcgt ctagcacaaa cggatcatct gattcaaatg attcaagtga aacaagtcaa
     8821 atagaagata atccaagtac aactccgtca agtttaaatg aaaattgata aaacaacttt
     8881 aaaaagtaag aatgtacttt ctaaaaacca gtaatttatg gtagaattgg aagcagtgaa
     8941 tatatctatt aataagtata ttttaaaacg gacgctagtt gttcgcttgt atatggaata
     9001 gtaagtagga gggaatccca ttcatggcaa aaacaggaat gtatgtaggc cttgatattg
     9061 gaacgacatc tgttaaagtt gtcgtggctg aatatatcga cagccaaatg aatattattg
     9121 gagtaggaaa cgcaaaatca gaagggatta accgaggcat tatcgttgat atcgataaaa
     9181 cggtccaagc gatacaacga gcagtacgac aagcagaaga aaaagcaggt atccagatca
     9241 aaggcgtaag tgtcggtttg ccagcaaaca tgcttgaagt agaaaattgc cagggaatga
     9301 ttgcagttaa cggagattca aaggaaatca ccgatgaaga tgtcagaaat gtggcttcag
     9361 ctgcccttgt tcgttcaata cctcctgaac gtcaaatcgt gtcaatattg ccacaagatt
     9421 ttactgtcga tgggttcgag ggaatcaaag atcctcgtgg aatgatcggc gtaagattag
     9481 aaatgtacgg tctgttgttt acaggaccta aaacgatcat ccataacata cgtaaatgcg
     9541 tggaaaatgc cggattaatc gtcaacgaaa tggtgattac tcctttagcg ctgactgaat
     9601 caattctttc tgacggagaa aaagattttg gtacgatcgt cattgatatg ggtggcggcc
     9661 aaacaacaac ggctgttatg catgataagc aattgaagtt taccaatctt gaccaagaag
     9721 gtggcgaatt tgtcactaaa gatatctcta ttgtattaaa tacgtcattt aacaatgcag
     9781 aagcgttgaa aataaactac ggggatgcat acccagaacg gacatcacca gatgaagaat
     9841 ttccagtaga tgtgattggt cagtcagaac cagtgaaagt cgatgaacgc tacttgtcag
     9901 aaattatttc agctcgaatg gaacagattt tcaacaaagc aaaagatgca ttggaccaaa
     9961 tcgaagcatt agagttgcca ggtggcgtcg tattgacagg cggagctgct agtcttcctg
    10021 gtgttgtgga cttggcacaa gaaatcttcg gcgtaaatgt aaaattgtat gttccaaatc
    10081 acatggggct gagaaacccg gtatttacaa atgtaataag tatcgtggat tattcagcaa
    10141 acttgagtga agtgtatcaa ttggcaaaaa ttgctgttac gggtgaaacc tcagcagctc
    10201 gtcaaatggt agttgaacaa gaaacaacaa acacatatga gagctatgaa gcacctgaag
    10261 aaacaatcta cgatgagccg gaaccaaaag agtccggaga aaatgtaaaa aataaaatca
    10321 agggtttctt tacaaatatt tttgattaat tcatcctggg aggaataaga tatggaattc
    10381 tcaattgata ataatatcaa tgacggcgca gtaatcaaag tcatcggagt cggtggtggc
    10441 ggtggaaatg ctgtaaaccg aatgattgaa gaaaacgtta aaggtgttga attcattaca
    10501 gccaacacag acgtgcaagc attaaaaaat tcaaaagctg aaacagttat ccaattaggc
    10561 cccaaatata ctcgtggttt aggtgctggt tctcagccag aagttggaca aaaagcggca
    10621 gaagaaagtg aacaatcctt acgcgaagct ttagacggtg cagatatgat tttcatcact
    10681 gcaggaatgg gtggaggaac cggtacaggt gctgcaccaa tcgttgcagg tatcgcgaaa
    10741 gaattgggcg cattgactgt tggtgtcgtg acacgtccat tcacttttga aggaccgaaa
    10801 cgtggccgtt ttgctgcaga aggtatcgct cgtttgaaag aaaatgtgga tacattatta
    10861 attatctcaa ataaccgttt attagaagtt gtagataaaa agacaccgat gcttgaagct
    10921 ttccgtgaag cagataatgt tttacgacaa ggtgtacaag gtatctctga tttgatcaca
    10981 gcgccaggtt acgttaacct tgactttgct gacgtgaaaa cagtgatgga aaaccaaggt
    11041 acagcattga tggggatcgg tgtggctagt ggagaagatc gcgtagtaga agcaacgaaa
    11101 aaagcaatct cctctccatt gcttgaaaca tctattgatg gagctgaaca agtacttctt
    11161 aacatcacag gcggtttgga tatgacattg ttcgaagcac aagatgcttc agatatcgta
    11221 gcaaatgcag caactggcga tgtaaatatc attctaggta catctatcaa tgaagaaatg
    11281 ggcgatgaaa tccgtgtgac ggtcatcgca acaggtatcg atgaatcaaa aaaggaacgc
    11341 aagtctagcc gaccagctag acaagcacaa atgcaatcac ctgctcaaaa gactgtatta
    11401 gatatggatc aagctaaacc aacttcttca gaagaagaaa acagttttgg cgattgggat
    11461 atcagacgtg aacaaaatgt tcgtcctaga gttgatgatt ccaattttga caatatcgaa
    11521 aaaaaagaat ttgatacatt caaccgcgaa gaaacaaaat ctcatggcga tgatgaatta
    11581 aatacgccac cgtttttccg tcgtaaaaaa taaaggagag gaagagcaca tgattgctga
    11641 caacttgcag aaaatcaagc aagaaattca ggattcgtgt gctcttgttc atcgtgatcc
    11701 gaaagaagtt acattagtag ctgtaacaaa atctgttgaa tccgctcaag ctgaagaatt
    11761 ggttagagct ggcgttatga attgtgcaga aaaccgagta gataaattat tagaaaagaa
    11821 acaagattta tttgattttc ctgaaataaa gtggcattta attggtaatt tacagcgcag
    11881 aaaggtaaaa ttgattgtaa atgaaattga ttactttcat gcgttggaca gtttaagatt
    11941 agcagaagaa atccagaagc ggttagagaa agaattatcc tgttttattg aagtaaatgt
    12001 ttctggtgag gaatcaaaac atggaatttc accagatgag cttttaccgt ttgtggaatc
    12061 tttagctgcc tgcacaaaaa tcaaggttgt tgggttgatg actatggcgc ctaaagaagc
    12121 ttctgatgag caaatccata aagtgtttgg tacgctgaaa gaattgcgtg atcttgttca
    12181 agcaaaaggt tatgcccatg caccatgtag tgaattaagt atggggatga gtcaagactt
    12241 tcaaattgcg attgaagaag gtgcaacatt tatccgtgta ggaacagcgc tattcaaaga
    12301 cgaataaagg aggaacaaaa atgccgcttt taaacagagg agcaattgct aattttttcg
    12361 gattagctga tgaggaagag tacgaatacc aagattatcc tgaaacaaca aaaaaggctg
    12421 tacagccaac taaaaaaaat acaacacaga atcaatcaac tcattctgta tctgctgcga
    12481 atactcatga aaaacaaaaa acggcgactt cacgtcctgt aacgcatgaa agtattcagc
    12541 cggctgaaaa gaaaaaagta attgaactac atcaatcacc tacaaaaact gtagcgaaag
    12601 aaagaacagc ttcaagaacc tctacacaac ctaaagcaaa tcttgctgga aaaatcactg
    12661 taatggaacc aagagcttat tctgaagcta tggcgattgc taaacgaatc attgctggag
    12721 aagcaacctt agtgaatttt catttagtag aagaaaaaca agcgagaaga atcgttgatt
    12781 ttctaacagg aacagtttat gcactagatg gagatatcaa acgtgttgga gatgagattt
    12841 ttctttgtac accgactggg atggagattg acagttcaac cgctcaatct tttgcagatg
    12901 cgaatttgtt tgatctgtaa gaggaggaac tacgatttat actattgcac tattacttca
    12961 tttacttcaa cgggcagcct atttctatag cattatcttg atggtatatg cattgctctc
    13021 ttggtttcca ggcgggtatc aatcagggct aggacgatta ttagctaaga tctgcgaacc
    13081 gtatatcagt ttgttcgatc gtctgccttt gaggattgga cccttggatt tcacaatttt
    13141 aggggcaatc ctgatcttga acttagccgt acaaggttta gcacagatcg ttatatggat
    13201 aactgtccat ttagtttatt gattgaagca acaaaatctt tattctcaga atagatagga
    13261 ggggaaaatt ttggatgcaa atgtatacca gcactttcgg gcagatgaac gtacatttat
    13321 cgattcggta ggcgattgga ttgaacaggt tcaaggacaa tatgcaccct atctgaccga
    13381 atttcttgac ccaagacaat cctatatttt agaaacactg attcgacaaa gcagtgattt
    13441 gcgtttcatg ttttatggcg gatatgaaca ggcagaaaga aaaagatgtt tgattttccc
    13501 cgattattac gaacctgtag aggaagattt tgaaacagca ttgtatgaaa tccattatcc
    13561 tagcaaattt gccagcctaa gtcatgggaa aatccttgga actttagtgg gaacggggat
    13621 caaacgctct tactttggcg atatcatctc ggacggtgat cgctggcaag tatttattgc
    13681 aaatgaggtg gatcattttg ttgctgcaca agtaacaaag attggaaagg ttgctgtacg
    13741 cttggaacca atcaaataca cagaaatgat tatgccgaaa gatagctgga cacaagaaag
    13801 aggaacagtt agttccatgc gactagacag tgtgatctct gagatttata atatttccag
    13861 acagcggtcc aagcagctga tcgaagctgg taaagtaaaa gtgaactgga cagaaaatac
    13921 aagacctgat tttgtacttg aactattaga tattatttca gtcagaggtt atggcagagt
    13981 ccagatccaa gaacttgagg ggaagacgaa aaaagaaaag tacagggtac tgttcggtgt
    14041 attacgtaaa taaaataaaa aggtggttta ctcatggctt taactccatt agatatccaa
    14101 aataagacat tcccgacaaa aatgcgggga tataatcaag acgaagtaga tgatttctta
    14161 gatttagttg ttcgtgacta tgaggaattg actcaaagaa atcgagaatt agaaaaagca
    14221 gtcaaacatt ctgaagaaaa acttgagtac ttcaatgaat taaaagatgc tttgaaccaa
    14281 tcaatcatcg tagctcaaga tacggctgat aaagtaaaaa caagtgcaag caaggaatcc
    14341 gaagtgatcg ttacttctgc acaaaacaaa gcagatgagt tagttgcgaa cgctgaaaaa
    14401 cgtgcacatc aattaacaac tgatgcagaa gaaaaagcaa gaaaaatctt gacagatgca
    14461 acagaaaaag caagacagct tgcgacagaa actgaagatc ttaagaaaaa aacacgagta
    14521 ttccatcaac gtatcagctt gatgcttgag tctcaattag aacaagtgaa aagtccggaa
    14581 tgggatgaaa ttttacaacc attctccagc tacgtgactg acagccatga agtgatcaaa
    14641 gaagttttag caaaacagct tgacaatgaa aatgatactg atgtaaactc agacacagga
    14701 gtcatagaag cacctatgac ggcatttgat acacaggcta ttgatatctc gatcgtgcct
    14761 ggtgaaaatg aaaacgagta gaacagaaaa gcactttgtt attcttaaag cgagccgatg
    14821 agagtggaag ttcggtaaga cactgcatgg tgaaagatcc tctacttgag acctgctttt
    14881 ccgaaattag agtaagaagc agcggctgac ctcgttattg gtcacagaga gtttgcacta
    14941 gatagatgca actaaatttg ggtggtacca cggcatgttc gtcccttgcg gctgaacatg
    15001 cttttttgtg tccggaaaac aaataaagga gtgtatggtt gaatgaaaat gaaagaaacc
    15061 ttgcaattag gaaaaacaaa attccctatg cgtggtaatt tgccaaaccg agaaggcgag
    15121 tggcaaaaag aatgggaaga aaatcgaatc taccaaaaaa gacaagagtt gaacgaagga
    15181 aaacctagct ttgttcttca tgatggacct ccatatgcca atggtaatat ccatttagga
    15241 cattcattga ataaaatcag taaagacatt atcattcgtt caaaatcaat gtctggctat
    15301 cgtgcaccat atgttccagg atgggataca catggattgc cgattgaaca agtattggct
    15361 aataaaggcg tgaaacgtaa agaaatgtcc atggcagaat acttggaaaa atgtcgtgaa
    15421 tatgcacttt cccaagtaga taagcaacga gcagatttca aacgcctagg agttgcagga
    15481 gattgggaac atccttatgt tacattagat ccttcttatg aagctgcaca agtacgcgta
    15541 tttggtaaaa tggctgaaaa aggctatatt tacaaaggat tgaaaccaat ttactggtct
    15601 ccgtcaagtg agtcttcttt agcggaagct gaaattgaat ataaagatgt aaaatctcca
    15661 tctatttttg tagctttcaa tgtcaaagac ggcaaagata ttcttgatga agatacagct
    15721 tttgtcattt ggacgacaac accatggaca ttgccagcaa accaaggtat tgctgtaaat
    15781 ccaaaattta cgtatgtatt ggtggaagcc gatggccgta agtttgtcgt agcgaaagat
    15841 ttgctagaaa cagtccaatc agaaatcggt tgggaaaatg taacagttct aaaagaattt
    15901 gctggacaag aaatggaata tatgactgca agtcatccat tctatgaacg tgaatcactt
    15961 gtgattttag gcgatcatgt tactttagac gctggtactg gattagtcca tactgctcca
    16021 ggacatgggg aagatgacta tatcgctggt agcaaatata aactatctgt agtgtcacct
    16081 gtagactcaa aaggattgtt tacagaagaa gcacctggat ttgaaggtat cttttatgac
    16141 aaagcaaatc ctatgatcac tgatctatta aaagaaaaag gagctttgct gaagctagat
    16201 ttctttactc atagttatcc tcacgattgg cggacgaaaa agcctgtgat ctatcgggca
    16261 actccacaat ggtttgcatc tatcgataaa ttccgtcaga atattttgga tgaagtagaa
    16321 aaagtagagt gggttatccc atggggtaaa acacgtttgt ataatatgat ccgtgaccgc
    16381 ggcgattggg taatttcccg tcagcgtgca tggggagtac cacttccgat tttctatgct
    16441 gaaaatggag aagcaatcat cacaccagaa acaatcgaac atgtggcaaa attatttgct
    16501 gaacatggat caattatctg gtttgaaaaa gaagcgaaag aacttcttcc tgaaggattt
    16561 acccacccag gttctcctaa tggcgaattt acaaaagaaa aagatatcat ggatgtctgg
    16621 tttgattctg gttcttctca tgaagctgtt ttacgtcagc gaccagaatt atcattccca
    16681 gcagatatgt atttagaagg atcagaccaa tatcgtggct ggttcaactc aagtatcacg
    16741 actagtgtgg ctatcaatgg tgtagcacca tacaaatcag ttatttctca aggatttgct
    16801 ttagatggtg aaggccgtaa gatgagtaaa tctttaggaa acatcattgc accagaaaaa
    16861 gtgatcaaac aatttggtgc agatatcctt cgcttatggg tatctagtgt agattatgaa
    16921 gcagatgttc gtgtttctat ggatatctta agtcaagtgg cagaagtata tcgtaaaatc
    16981 agaaatacga tgcgtttctt attagcgaat acagaagatt tcgatcctaa aaaagatact
    17041 gtttcgtaca atgatttacg ttctgtagac aaatatatga ccgttcgatt gaaccaagta
    17101 atcaaagaaa tccgagaaga agggtacgac aaatataact tcatgcatat ttaccgtaca
    17161 gttatgaact tcttgacggt tgatctatcg tcattctacc tggattttgc taaagatgta
    17221 gtttatattg aagcagaaga tgattatcaa cgtcgttgca tgcaaactgt tttctatcaa
    17281 acagctgtag ctttgacaaa attattgact cctatcattc cgcatacagc agaagaaatc
    17341 tggtcattcc tgaaagaaga agaggagtac gttcagttaa gcgagtttcc tggttatgaa
    17401 gagtttgcaa accaagaaga attgatggat acctggactg ctttcatgga cttccgtgat
    17461 aatgtcttaa aagcattgga agaagcaaga aacagcaaat tgattggtaa atctttggaa
    17521 gcaaaactaa ctgtttatcc aaaacaacaa gttcgtgaaa tgttaaaagc tttggatgca
    17581 gatattgcac aattattgat cgtttcacca gactactttg aagttatggc agcagatgaa
    17641 caagtgccag ataacgctat ggtatttgat gatgttgcta ttacagtgga aaaagcagac
    17701 ggggaaactt gcgatcgctg tcgccaagtt cgtaaagatg taggagtaga tgaaaaactt
    17761 cctcatctat gcggtcgttg tgcaaaaatc gttgaagact tctatcctga agctgtagct
    17821 gaaggattcg aagaaaagta aaagggaaaa gggggtgtga catgtt
//
LOCUS       DAMEEU010000059        17529 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.060, whole genome shotgun sequence.
ACCESSION   DAMEEU010000059 DAMEEU010000000
VERSION     DAMEEU010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17529)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17529)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17529
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.060"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            223..591
                     /locus_tag="PB779_002046"
     CDS             223..591
                     /locus_tag="PB779_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HDE0739564.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            771..1712
                     /locus_tag="PB779_002047"
     CDS             771..1712
                     /locus_tag="PB779_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HDE0739565.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
     gene            1781..2512
                     /locus_tag="PB779_002048"
     CDS             1781..2512
                     /locus_tag="PB779_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HDE0739566.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            2656..4836
                     /locus_tag="PB779_002049"
     CDS             2656..4836
                     /locus_tag="PB779_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HDE0739567.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            4856..5338
                     /locus_tag="PB779_002050"
     CDS             4856..5338
                     /locus_tag="PB779_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HDE0739568.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            5354..6115
                     /locus_tag="PB779_002051"
     CDS             5354..6115
                     /locus_tag="PB779_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HDE0739569.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            6246..7580
                     /locus_tag="PB779_002052"
     CDS             6246..7580
                     /locus_tag="PB779_002052"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HDE0739570.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            7887..8372
                     /locus_tag="PB779_002053"
     CDS             7887..8372
                     /locus_tag="PB779_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HDE0739571.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            8365..9048
                     /locus_tag="PB779_002054"
     CDS             8365..9048
                     /locus_tag="PB779_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HDE0739572.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            9174..11819
                     /gene="polA"
                     /locus_tag="PB779_002055"
     CDS             9174..11819
                     /gene="polA"
                     /locus_tag="PB779_002055"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HDE0739573.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELAEKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            11864..12700
                     /gene="mutM"
                     /locus_tag="PB779_002056"
     CDS             11864..12700
                     /gene="mutM"
                     /locus_tag="PB779_002056"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HDE0739574.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            12664..13293
                     /locus_tag="PB779_002057"
     CDS             12664..13293
                     /locus_tag="PB779_002057"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HDE0739575.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            13345..13677
                     /locus_tag="PB779_002058"
     CDS             13345..13677
                     /locus_tag="PB779_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HDE0739576.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHIPDEQKIEEQRMKH
                     YTGIEEKL"
     gene            13989..14480
                     /gene="nrdR"
                     /locus_tag="PB779_002059"
     CDS             13989..14480
                     /gene="nrdR"
                     /locus_tag="PB779_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HDE0739577.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            14503..15876
                     /locus_tag="PB779_002060"
     CDS             14503..15876
                     /locus_tag="PB779_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDE0739578.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            15876..16802
                     /gene="dnaI"
                     /locus_tag="PB779_002061"
     CDS             15876..16802
                     /gene="dnaI"
                     /locus_tag="PB779_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HDE0739579.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            16931..17371
                     /locus_tag="PB779_002062"
     CDS             16931..17371
                     /locus_tag="PB779_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HDE0739580.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
BASE COUNT         5980 a         3056 c         3847 g         4646 t
ORIGIN      
        1 tttttagtca cgacctcttt ttttatttat tccatataaa tacacattat ttattccgaa
       61 aagtgaaagc gcaaataaca aaaacaacca acttatttat tattaaagaa aagcgtattt
      121 aagtaggacg attctgttga gagctttcgt agattttccc attttcctat ggtaaactga
      181 caaagttgag aatgttagaa cagatcgttt aggaggaaac agatgtttac gaatgaaata
      241 aaaatcatgc tttatgtgga cgatgtagaa aaaaatgcaa cgttttggag agcagttggc
      301 tttgcggaaa aagatcgtca agaaatggat gggacgctta taattgaagt aggagttgag
      361 gacagtcaaa cctcatttct gttatatgat cgagcatttg ttgagtccca ttcacctggc
      421 acagctacta gtgccccatc tttgatgttt tacagtaaag atatctttgg actatataaa
      481 aaaatgcaga cgcaatcagt cacattaggt gatatggtac agcttggaga agaatatgtc
      541 tttaactttg ctgatcccga tggcaactac tttgcggtta caggtaaata atagaaataa
      601 agactttgtt tttctgtgcg aaacaggaaa gcgaagtctt tttaattcaa ataataatat
      661 tatgtaaaca aaaaactttc catgcgtaat tatacacaag caaataaatc gtcaaatgcg
      721 aacgccttct ttatactgtt taggaacgaa aagaaggaag gaagaaatac atggattatc
      781 aagtactgct ttattacaat tatacaaaaa tcgaagaacc agaggaattt gccaaaaatc
      841 atttagcctt ttgcaaatct ttggatctta aaggtcgtat tctagtagct gaagaaggaa
      901 taaatggtac tgtgtctgga accgttgaaa acacgactgc ctatatgaaa gcaatgaaag
      961 ctgatcctcg atttgctgat acgatgttca agatcgatcc aagcgaagga catgccttta
     1021 agaagatgtt tgtaagatac cgtccagagc ttgtaagttt aaagctagaa gaggacattg
     1081 atccaaacca agtgacaggt gcctatcttt caccgcaaga atttaaagaa gctattttag
     1141 atgaacagac agtggtgatt gatgcacgga atgattatga atatgacttg ggacattttc
     1201 gaggggctgt acgcccagat atacgcagtt ttcgagagct tccagactgg atccgcgagc
     1261 acaaagaaga atttatggaa aaacgggtag tgacctactg tactggtggc attcgttgcg
     1321 agaagttttc tggttggctt gtccgtgaag gattcaaaga tgtcggacag ctgcatggcg
     1381 gtattgctac ttatggtaag gatcctgaag tccaaggaga attatgggac ggcaagatgt
     1441 atgtgtttga tgaacggatc gctgtcgata tcaaccaagt agataaacaa atcgtcggtc
     1501 gcgactggtt tgacggaaca ccatgtgaac gatatatcaa ttgtagcaat cctgagtgca
     1561 atcgtcagat tcttgcttcc attgaaaatg aagaaaaaca tttaggagca tgtagcatag
     1621 agtgtgcgaa acatccgcgc aatcgctatg ttcaagacca tggaatctct ccagaagaag
     1681 cagaactgcg gtttacagct ttaattaaat agaaaacaat agttttgatt gtcgaccatt
     1741 tccaatatgc gctatactag cgttgaggat ggtgatccac atgaaatcat tgatttatgc
     1801 tattggggat gtccatggca aacatgagct ttttgaaaaa cttattcact attatgatcc
     1861 aaagatccat cagcttgttt tattagggga tctcaatgat cgaggtcctc gtacaaaaga
     1921 atgtttttta ttaggaaagc aattagtcga agaaacagga gccatttacc tccggggaaa
     1981 ccatgaagaa tattttttgc aatttctgca atcaccggag gactggtatg cgccttatat
     2041 gagaaatggt ggaaaagaaa cgtttgaaag cctgattcac ccaggggcat cggaggaata
     2101 ctccccaact gaaatctcga tgatgatcca atcgagatat tcagaactga ttaaattttt
     2161 agtccagcgc cccttgtatt atgaatggga aaattatctt tttgtccatg ccggtgtgga
     2221 tttgacaaag aaagactggc gtaagacaag tctaagagac tttatttgga taagggaacc
     2281 atttcatgaa gggaaaaaca atacaggtaa gacaattgta tttggacata cgattacacc
     2341 aatgctccat ggagatatgc agacaacaga cctctggatt caggatcata aaatcggaat
     2401 ggacggtggg gctgtattcg gagggtcatt gcatggggtt gtttttgaca aggaaggtat
     2461 tcttcaagat attgaatatc agaacaacga aggaccttgg catggaatct gactaatgga
     2521 aagaatgaag gagctgtgac tttgttgcgg ctctttttat ttttatagag aatattgttt
     2581 ctttcagtag tttaacccag gataaaaagt atgatagaat aaagaagcaa tttttagcag
     2641 aaaagaggca ttttaatgac ggaaaatttg aaccagacga tcattcagct tgtacaaaaa
     2701 gaactttcag actatcgtcc taagcagttg actactgtac ttaatttgtt aaatgaagga
     2761 aacactgttc cttttatcgc gcgttaccga aaagaaatga ctggaagtct tgatgaagtc
     2821 cagattcgtg aaatcgaaga gcggtatgcc tatcttgaaa acttagaaaa acgtaaaact
     2881 gaagtgattc ggctaatcga tgaacaaggg aaactgactc ccgagttaga agcagaaatc
     2941 acccaagccg tgaaaatgca acaagtggaa gatttgtatc gtccatacaa acaaaaacga
     3001 cggacaaaag caacgattgc taaagaaaaa ggacttgaac cactcgcgaa gtggctgatg
     3061 cagcttacag atggagaggt gcaatctgaa gcagaaaaat atattgacaa agaaaaagaa
     3121 gtctcttctg ccgaagaagc gttgcacggt gctcatgaga ttattgctga acaagtcagc
     3181 gataatgcaa aatttcggac ttggattcgg tcttatacgt ataacaaagg tatgtatgtc
     3241 agcaatgtca aggatgagca agcagatgaa aaaggcgtat atgaaatgta ttatgacttt
     3301 gcagaacccg tccataaaat ggtttctcat cgaatattag ctactaatcg tggagaaaaa
     3361 gaagatattc tgaaagtatt ctttcaagta gatgaagcag caattttagc ttacttggat
     3421 cgccaaatag tcaaaaatcc tgcctctcct tcttcttcat tcgtcagaga agcctatcag
     3481 gatagttata aacgctttat tcagccagca atcgagcgag aactgcgcaa tgaattgact
     3541 gaaaaggcag atgagcaagc aatcgctatt ttcggcgaaa acctccgtaa tcttttgttg
     3601 caaccgccac taaaaggtaa agttgtcctg ggatttgatc cggcttatcg tactggatgt
     3661 aaactagcag tcgtagatgc gacagggaaa gttttagcaa tcgaagttat ttatcctcat
     3721 aaacctgcag cgcaagcaaa aagagaagct gctggaccag cttttatcca attaattaat
     3781 aaatatcaag tagatatggt agctatcgga aatggtacag ccagtcggga atctgaactt
     3841 tttgtggctg agcagttgaa atccgccgac cataaaacct attacgctat cgtcaacgaa
     3901 gcaggcgctt ctgtttactc cgctagcgaa attgcacgaa aagaatttcc gcatctacaa
     3961 gttgaagaaa gaagtgctgt ttctattgcc cgtcgcctgc aagatccttt agctgaatta
     4021 gtcaaaatcg atcctaaagc tgtcggagta ggccagtacc aacatgacgt ttctcaaaaa
     4081 cgtttggctg aacaattgga ttttgttgtg gaaacagcgg ttaaccaagt aggtgtggat
     4141 gtgaatacag caagcccgca gctcttgcag catatatcag gattgaataa aacaactgcc
     4201 caaaacattg tcatttatcg tgaagaaaac ggagaattca ccgcacgaac tcaattgaaa
     4261 aaagtgccac gcttaggacc aaaagcatat gaacaagcaa tcggattctt gcgagtccct
     4321 ggtgggaaaa acattttgga caacacaggt atccatcccg aaagttattc tattgcaaaa
     4381 gaaatattaa cttcagtcca actttcagaa aaagagcttg gtacagaaga agcagtagaa
     4441 aaattgacac gattatccgt agagaaactg gctgaaagcc tatcagtcgg agaagaaacg
     4501 ttagccgata ttttagctgg gctgacacaa cctggacgag atatgcgtga tgagatgcca
     4561 gcgcccttat tacgtacaga tgtattgagt atggaagact tgaaaccagg gatggaattg
     4621 actggaacgg tccgtaatgt cattgacttc ggcgcatttg ttgatatcgg tgtgaagcaa
     4681 gacggacttg tccatatatc gaaactcagc aaaaaattcg tcaagcatcc tacagatgtc
     4741 gtgtcagtag gagatatcgt aacagtttgg atagaacaag tcgatacgaa aaaaggtaga
     4801 atcagtttga cgatgctttc cccttatgaa gagtaacaat gaggagtaac aaaaattgac
     4861 acaagaagaa ctgcagcagt tagtagaaga gatatcatta aaaagcttcc agcttccttt
     4921 caagcaccaa gcaatgttca atccacgctt acgtacaact ggcgggcgct atcatttaaa
     4981 cgatcatcat ttagatttta atgcgaagct atttgaagag tcagacgaag agacgattgc
     5041 aggaatcatc aaacatgaac tttgccatta tcatcttcat ctagctggaa gagggtatca
     5101 gcataaagat atggatttca agtatctttt gaaaaaaaca ggagggttgc gctatgcacc
     5161 agccttgacg aagaaacaga taaagatgga gtattatcga tgccaagatt gttctgccac
     5221 gatctgccgc aagagaagaa tcgatgtacg caaatatcgt tgtggaagat gtcatggaga
     5281 aatcaaatgg attgagacaa aaagagaaga ctttaatgaa gcacaaaaaa tcagatgaaa
     5341 ggatagaagg cctttggaaa aaagtgagca gaggaatcta aaagactgga atcagctatt
     5401 aaatttttta gccgcacctg aagagggaaa ttttgaggaa ctgacggcac ctacacttat
     5461 tttagctgga aactgtcttc ctatcttagc tgataaagca gcacaaatgt atttaaatgg
     5521 ccaagtagat caattgtttt tggtcggagg ggtggggcat gcgactagaa tcctttatga
     5581 gaattttgaa aagcaaggat ttcattttga agatggcatg agtgaaagtg aaatctgtcg
     5641 tcagtatcta aaagaagtct atgatttgcc cgataaggct tttctgatag aatcgaagtc
     5701 tacaaattct ggagagaacg ccactttttc actggagatt cttcattcct taggagctgt
     5761 accagaaaaa atcttattga tgaatgatcc gacactgcaa cgcaggactc gagcaacttt
     5821 tgagaaagta tggcaaaatg aacaaactat tttcgcgaat gctgtgccat ttgtgccgga
     5881 aatccttcac ttttctgaag agatcatctt tacagcaaaa gaactgaatc atcaatggcc
     5941 taaggaatat ttccatgcgc tagtattagg agaaatggaa cgtctccatg acgatgagaa
     6001 cggctatggt ccgaaaggaa aagattttat tcctcacatt gatatatcag aggaagtttg
     6061 gtcttcttac accagaatta aagagtcaat aaaaacggat ttttctcgta cttgaccatt
     6121 ttagcaagcg aatcctcctt tccaaataaa tttggttgaa attttcaatc gtttataaga
     6181 taatgaggag cgtgttgaat gtaatagcta aaagaatgga cgctagataa gagaagagga
     6241 ttcaaatgga aaatcaaaat aaattgtatc attttgttgg tatcaaaggt tcaggaatga
     6301 gctccttggc tcttgtttta catgaacaag gtctaaatgt ccaaggatca gacattgaaa
     6361 aatatttctt tacacaaaga gatttagaaa aagcaaatat cacgattctg ccatttaacg
     6421 cagataatgt aaaaccaggg atgacgatca ttgcaggaaa tgcatttcct gattcacatg
     6481 aagaaatcca gcgagcaaaa gaattaggtt tggaagtgat tcgctatcac gactttattg
     6541 gtcattttat ccaaaattat acgagtatcg ctgtaacagg ctctcacgga aaaacaagta
     6601 cgactggact gctctctcat gtattgagtg gtgtccgtcc aacaagttat ctaattggag
     6661 atggaacagg acatggtgat ccgcaagcgg aattcttttc atttgaggcc tgtgaatatc
     6721 gccgtcattt ccttgcctat tcaccagact atgcaatcat gaccaatatc gattttgatc
     6781 atccggatta ttatacaagt atcgacgatg tatttacagc tttccaaaca atggctggac
     6841 aagtgaaaaa agctattttt gcgtatggtg acgatgctta tttacgcaaa ttaaaagcaa
     6901 atgtgccgat ttattattat ggtgtcacag aaaacgatga tatccaagca cgaaacatcg
     6961 aacgcacaac ttctggttct gcttttgatg tctatcatgg ggatgaattt gttgggcact
     7021 tcactgtacc agcattcggt aaacacaata tcttaaatgc tttaggtgtt attgcagtag
     7081 cttatttcga aaaactggat ctgaaagaag ttgcagaaga aatgctgact ttcccaggag
     7141 taaaacgtcg attcagtgaa aagatcgtag cagacatgac cgtagtcgat gattatgcgc
     7201 atcaccctgc agagatcaaa gcaacgattg atggcgcacg ccaaaaatat ccagataaag
     7261 aaataattgc agttttccaa ccccatacgt ttacgcgtac gattgcattg atggatgaat
     7321 ttgcagaagc acttgattta gctgataaag tttacttatg cgatattttt ggttcggctc
     7381 gggaagaaca aggaaacgtt aagattgaag accttggagc gaaaatcaaa aaaggtggag
     7441 aagtcatcaa agaaaataat gtatctccat tgttagatta tcatgatgca gtagtaatct
     7501 tcatgggtgc tggagatgtt caaaaatttg aacaagcgta tgaaaaactt ttaagcagca
     7561 cgacgaaaaa tgtactgtaa tacaattact gcagtgtcct tataaaaata gaaagagggg
     7621 gagtggcaaa aatcttgcca agcccccttt tttgcaactt atgataaacg gtgttcaaaa
     7681 gcttgcatct gcggtaataa gcccaatcaa atcaaaaaca tgagaagctg ttttttcttg
     7741 gctgttctta ttatttgatg caggacagct ttttcacgac ctctgtaaac tataggaatc
     7801 tgttaaatca agggagcaga acttgccttt tacgctactt ttggtacaat aatgtatgat
     7861 taaaaataaa ctggagggtt tctatcttga acataggtaa gccgagaaaa ctaggaaaaa
     7921 caataaatga aatcgaggaa ggcgactcgt tatccttaac agaatctatt gaagataacc
     7981 agcttttgct gtatttggga ttgacgaatg atgcaaatcc tttgtatatc caacatgact
     8041 ttgcacaaaa aacagaatat caacagccaa tcgttccatc agtgatgctg atggggatca
     8101 tcacaagtgc aatttcaaag catcttcctg gaccaggatc acatgttgtc aatttttctg
     8161 tcaattttat tgaaccggtt ttccattatg aaacactgac ttttcagttt gaggtcataa
     8221 aagtagataa gatgaaggat gtggtgacga tttctgtaga agcggagaat acgaacgaag
     8281 atcgtgtgtt ggatgctgtc gttatggtcc aaccgccaca agttcctgaa ttggaaatag
     8341 caatcgaaag tgaaggtgaa ttgaatgaat aatccaagta catcaatgtc aggtatcaat
     8401 cgtttttatg caaaagttta tggattttta ggtatgggac ttgcccttag tgcagtcact
     8461 tcttacttgg ctctttgggt atttcctttg caattagcaa cttttatcaa taattttcca
     8521 ctaggctttg tgggtctgtg gatcgttgaa ctgattttag taatggttct aggcgtaaaa
     8581 gcacaaaaga atccgagctt agcaatcggt ggatttattg cctactctct tttgaatggc
     8641 ataacattag cggttactct tgcatactac gatattggaa cagtaacgca agctttcttg
     8701 acagctactt tgatgttcat ggggatgtct gttgtcggag taacaacaaa aagagatctt
     8761 agcggggttg gaagagcagg acaggcagct ttaatcggag tgatcattgc actagtcttg
     8821 aacatcttca ttttgagaag tagcgtagtt gagctgttca tctccctact gttagtcgtc
     8881 atctttgcag ggattacagc ttatgataac caaagcatcc gtaatatcta tgtccagaca
     8941 aacggaacag cacatagtgg aattgctgta ttcatggcat tgaagctgta tttggacttt
     9001 atcaacttgt tcttggcgtt tctgagaatc tttggacgga acaactaaaa aagaaaaaaa
     9061 ttcatcagtt ggggctatac cgaattattt ggtatggtcc cgctttttct tttcgcattc
     9121 cgcaggattc tttgttagaa tgaataagaa ctttacagta aggagttaag aagatgacaa
     9181 aaaataaatt attactcgtt gatgggaaca gtgtggcttt tcgcgcattc tttgcgcttc
     9241 acaattctct tgaacgtttc aaaaatagaa acggtcttca tacaaatgca atctatgcat
     9301 tcaatacgat gtttgaaaat gttatgcaaa aagagcaacc gactcatgtt ctggttgcgt
     9361 tcgatgcagg aaaaacgact tttcggacag aaatgtatgc ggagtacaaa ggtggaagat
     9421 ccaaaacacc tggcgaattc aaagaacaaa tgccatatat acgtgatttg ttgacaggac
     9481 taggggtaca gtattacgaa ttgcccaatt atgaagcaga tgatattatc ggtactttgg
     9541 cagaaaaagt agacaaagat caatttgatg tcgtcgtgct ttcaggtgat cgggatttga
     9601 ctcaattagc tagtaaagaa gtaaaagtgg atatcactgt aaaaggtgtc agcgatatcg
     9661 aaagctatac accagaacat gtagcggaaa aatatgatgg gttgacgcca aaacagatta
     9721 ttgacatgaa gggactagcc ggagatgcct ctgacaatat ccccggtgtg actaaaatcg
     9781 gtgaaaaaac agctatcaag ctattgaaac aatatggctc agtcgaagga atttatgaac
     9841 atatcgatga aatgaagcaa agcaaaatga aagaaaatct gataaatgac aaagagcagg
     9901 ctttcttatc gaaaaaattg gcgaccatca atacttcagc gcctgtggat gtctctatcg
     9961 actcattgaa gtatgaaggg aaaaatctcg ataaactcgt tccgttttat aaagaaatgg
    10021 atttcaatca gttcctttct aaattgaata tcgtagaaga agaagtaaaa atggatgata
    10081 ttttgtttga agtcgttcat gaattcaaag aggaaatgtt tactacggat atggcgttgt
    10141 acgtggaaat gatgggcgac aattatcata cagaggaaat cgtcggagta gcgtggggga
    10201 cagaaaagaa aatttatgtc acgaacgatc tatctgtatt cgaaaaccga gcgttccatt
    10261 cttggatcac tgatccgact cggctgaaaa aagtatatga tgcgaaacga acttatgttg
    10321 ctttaaaccg ctatactgga aaaacgaaag gaatcgattt tgatgtcttg ctaggtgcat
    10381 accttctcga tacgaatgaa aaaagcacag atatcgaagg aatagctgct cattacggat
    10441 acaacgatat ccaatcagat gaagctgtat acggcaaagg ggcgaaaaaa ggtttaccag
    10501 aagaagagga actctttttt gctcatttag cgcgaaaagt agctgcaatc aatgcgttga
    10561 caccaaaatt gagccaagaa ctggcagaaa aaaaccaaga agatcttttc cggaaaatgg
    10621 aactgccatt gtctatcatt ttggcagaga tggaaataag cgggatcaaa gtagatgcga
    10681 ctcgcttaca agaaatgaag ggcgagttct ctgctcgctt aagagagatc gaacaaaaaa
    10741 tctacgaaga agccggcgaa gaattcaatt tgaattcacc aaagcaatta ggagtgatct
    10801 tatttgaaaa aatgggatta cccgttatca aaaaaacaaa aactggatat tccacagccg
    10861 tagatgtact ggaacagctt cgtgaacaag caccaatcgt agaggatatc ctcacctatc
    10921 gtcaaattgc aaaaattcaa tctacctatg tcgagggact gctgaaagtg atccaatcag
    10981 atggaaaagt gcatacccgt tatgtccaga cattgaccca aacaggacga ttaagctctg
    11041 ttgatcctaa tttgcagaac atcccgattc gattagatga agggagaaag atacgtcagg
    11101 catttgttcc tagagaaaaa gactggctga tttattcttc tgactattca caaatcgagt
    11161 tacgcgtact tgcgcatatc tcaaatgatg aacatttgaa agctgccttc ctagaaggtc
    11221 aagatatcca tgccagcaca gcgatgcgtg tatttggaat cgaaaaggca gaggatgtca
    11281 caccaaatat gcgtaggcag gcaaaagcag tgaattttgg tatcgtgtat ggcatctctg
    11341 attacggact ttcacaaaat ctaggaatca gccgaaaagc agcacagcaa tacatcgata
    11401 cgtactttga aaaataccca ggtgtcaaag aatatatgga aagaatcgta cgcgaagcaa
    11461 aagaccaagg ctacgtcgaa acgctgtatc accgccgtcg atatctgcca gacatcaatt
    11521 caagaaatta caatatccgt tcttttgcgg aacgaacagc tatcaataca ccaatccaag
    11581 gaagtgctgc tgatattttg aaaatcgcga tgatcgaatt ggataaacga ttaaaagaaa
    11641 caggtcttca agctacgatg ctgttacaag ttcatgatga acttgtcttc gaggtaccgg
    11701 aaaaagaact tgaatcatta gataaattgg tgaaggaagt tatggaacaa gctgtttctc
    11761 ttcatgtacc actgatcact gacagcagtt ggggaaaaac gtggtacgaa gcaaaataaa
    11821 cattgtttaa gacagagcaa tataatgaag gtgaaaagaa aaaatgccag aattaccaga
    11881 agtagaaacc gttcgtaaag gattggaacg gttagtagta ggaaaaacga ttcaaaaagt
    11941 tcaggtcttg tggcccaaga tcatcgagca accagagaca cccatctttg aggcttctct
    12001 tgttggcgaa accatccaat ccattggacg tagagggaag tttttaattt ttcatctcga
    12061 tcattgtgaa ctgatctcac acttgcgaat ggaaggaaaa tatcaattta cgaaagaaaa
    12121 tacaccaatc gataaacata cgcatgtact tttctttttt gaggatggaa gccaacttcg
    12181 ctacaacgat gtacgaaaat ttggtcgtat gacaatcgtc gaaaaaggag caagtgcaac
    12241 ttaccgagga atcatgaaat tgggacctga gcctttgcca gatagcttct tattagcaga
    12301 tttcgcaaat ggactgaaaa agtcccacaa agcaatcaag ccattgctgc tagaccaacg
    12361 tctagtgact ggtctaggta atatttatgt agatgaagca ttatgggaag cgaagatcca
    12421 tccagaacaa ccggcgaaca cactgcgccc caaagaggta gaacaattac gtctatcgat
    12481 cattgatgtt ttggatcgtg caatagaagc cggaggtacc acgattcgca gttatttgaa
    12541 tgcattagga gaatcaggcg gatttcaagt agcactgcat gtctatcagc aaactggcaa
    12601 accatgtata cgttgtggaa cgccgatcgt gaaaacaaaa gtggcacaaa gggggacgca
    12661 ctattgtccg aattgtcaaa ggctaaaaat cgcaaagtag gatttgtttt aggtttgacg
    12721 ggtggaatag ctaccggtaa aagtacggca gccaaagtct ttcagtctca tggatttcct
    12781 ttgatcgatg gcgatgtgat tgccagagaa actgttgagc ctggaacgct tgctctgagg
    12841 aaaattgtat cagtgtttgg ccaagaggta ttgcagcctg atgggcaact agatcgaggg
    12901 aaacttggga tgattgtttt tccatcaaag gaaaaacggc aaaaacttga tcagctatta
    12961 gatccgttta tccgaaaagc gataaaagat caaatcgcct ctctaagttc caatcatcct
    13021 ttagtaattg tagatatccc attgctctac gaaggtcatt atgaccacta tatggatgca
    13081 gtagctgtcg tttatactac gccagaaact cagcttcagc gtttgatgaa acgtaatcaa
    13141 ctgacgctag aacaagcgca gcagagaatt agtagtcaac ttccaatcga agaaaaaaag
    13201 cagcgtgcgg atattttgtt cgacaacaat ggaacaaaag aaaaacttgt gggacaaatc
    13261 gaaaattggc tttttgctaa tcgctttctt tgagtatctg tgtcaatttt gctatcctga
    13321 gtatatagaa agtgagggat agcgatggga tcattaaaaa atcaaaagga taaagtcgta
    13381 ggtaacgcaa aagaaaaaat cggcgagatg ctcaataaag aaaatctaat cgatgaaggt
    13441 cgtacgcaat cagaaacagc agaagaaaaa gaaaagcagt accaagcaag aatcgatgaa
    13501 atagaagacc agcaggcaga agaagaagcg aagcggcaag atttgactca agaacgaaaa
    13561 aatccgacac ctgatcgtag taaaacaccg ctcccagaaa gtgaccacat tcccgatgag
    13621 caaaaaatcg aggaacagcg aatgaaacac tatacaggaa tcgaagagaa gttataaaat
    13681 agtaaaaaat cgagatgtga cttgaagcag atgagaaggt gttcatctgc ttcaagtttt
    13741 ttgtgctaga tgactaaatc agcttttgtg taagttattt ctcagtaatc aaggtgatca
    13801 gtattggaaa attgaaattt agtaaggaca ggggacacaa ttacgcatga aagtagaaaa
    13861 aattgttctt atatccgtgt tttttgggta ggacagtcgc gtttgtgatt tgtttcgtgt
    13921 tataatacaa ctagttgtaa agaaagacac atcctttata taaaatgcga tgcaagaggt
    13981 gagacaaaat gagatgtccc agatgtcaac ataataattc acgagtaatc gacagccgtc
    14041 aagcagatga tggacgtgcg atccgtcgcc gtcgcgaatg tgagaattgt tcgttccgat
    14101 tcactacatt tgaacgaatt gaagctgctc cgttattagt aatcaagaaa aacggggaac
    14161 gcgaagagtt caatcgcgat aaaattttaa gaggactcat ccgttcagca gaaaaaagac
    14221 ctgtagctat ggaacaaatg gaacaaatcg tcaaccatgt cgaaaaccgc gtacgcagtc
    14281 tcggagaaaa cgaagtatcg acgaatctaa ttggtgaata tgtgatggaa gatttagttg
    14341 atttagacga aatcgcttat attcgttttg caagtgttta tcgccagttc aaagatatgt
    14401 ctgttttctt aaaagagttg caagatatcg tggataaagc aaaagaaaat aataaagaga
    14461 ataataaaga aaacaattaa gaaacaaaaa ggaggcattt ccttggaaaa tgcttggaaa
    14521 gagcttcaac caaaaaatat ttaccaagga agaaaagcgg ctccgctgag agaagacagc
    14581 aagaacgcct tgctgtatct ttatcagcca ctaatcggcg gagaagcctt gagtatctat
    14641 ttcaccctgt tatcagaaat ctctcaagaa tctggcaaag gtcctgaagg gatgcatgca
    14701 gatctgctta gtagtctagg ctgcggtatc ccgcaatttt atgatgcaag aaaaaagcta
    14761 gaaggaatcg gcttactgga tgtttatttt aaagaagata gtgatctggg acctcgtttt
    14821 atttatgagc tgttagaacc actcattcct aaagcatttt tcaaagactc tgttctggct
    14881 tttcttcttc tggaaaaagt tggtgaacga cgattccaga agcttaccca attctttgaa
    14941 cctaaaaggc atacagcaga gggatatcaa aaaatcacaa aaaaattttt agatgtttat
    15001 cgcttcaatg aagcagtgta cgctgctaat caagaaaaca tcgaatcgct gaataaatct
    15061 tttgaagaat ctgaatcagt agcattactt gaagcagatt cgacattcga ttggcagttt
    15121 ttgaatgatt ggctggcaaa aaaacatatt gcaagtcttg atgatccaat catcaaacaa
    15181 gtcgacatgt atcatcagct ttacggtttc gatgaattga cacttggcga actgatcagt
    15241 caatcttatg actttagtga acaaaaagta tctgaaaaag aactgcaaaa agccattttg
    15301 gcaatgcaga gacgtccggt gaagcaaaca aaagaaacag ttgcggtttc tgaaaacagt
    15361 aatgaaccct cgtcaaacga acatttgaca aacgcagcgc ttcagctgat aaaagaagca
    15421 cagagcattc caccgatgaa atatctggaa gcaatcaagt cagaaaaagg cggatatgtt
    15481 tctaaacaag aaaactggtt actgcaagat cttgtttctc aatcaggtct ttccagtagc
    15541 gtgatcaatg ttttgctgaa ttatgtacta gtgatcaaga ataatgctag cttaaatgcc
    15601 agttatgtaa atacagtggc aaatgaatgg gcacaaaaga aaatcgccac agcagaagaa
    15661 gcgatccagc acattcggca aataagtaat caagcaaaac aatcaaaaca aaagaagcaa
    15721 acaaattatc aaactggcaa gcgaaatgtt cgacgggaaa agcttcctga ttgggtcaac
    15781 cagccaaaag atgaaaaaca gatcagcagc gagaaaaaag cagagattga ccgccgtttt
    15841 aaagaatacc tggcaaaaaa ggagggtgat atctagtgga agacgtaggc aaagaattga
    15901 agaggatcat cagcaaacgc aattatcaag aaaagtatgc tgaaatgatc gctgaagtct
    15961 taaatgatgc ggatgttcaa gcttttctaa gcgcacacca agaagaattg acacaagcgg
    16021 atattgaaaa aagttacgct aaattgtatg aattcgtgca agaaaagcgt aaatatcaaa
    16081 aaaacgatcc aacgatgatc gctcccggct atgagccgaa gctgacgttg aattttcatt
    16141 atgtggatgt cacttatgta ccaacggaag cattgttagc acggcaaaga caagaagaaa
    16201 tcagaagccg agtaaaagca atggatatgc caaaagatat tcaatcggct tcttttgaaa
    16261 actttgaacg tacagatgga cgaggatatg cgagcttaga agccctagat tttgtagaga
    16321 aatatactgc tgatccaaaa gggtatcata aaggactgta tctagtagga agttttggta
    16381 ttggaaaaac atatttatta ggagcaacag cgagagaatt agcgattgct ggattcacca
    16441 cgacgctagt ccattttccg acatttgccg ttgagatgaa acaggcaatc ggaaaagatc
    16501 aagtggcaga aaagttagat gcagtgaaac gttcacctat tttgatgatc gatgacattg
    16561 gtgcagatgc gatgagtagt tggatacgag acgaagtatt cggtgttatc cttcaatatc
    16621 ggatgcagga acagttacca accttcttct catcgaattt tacaatggat gaattggaac
    16681 agcatttgtc cgtcactcaa cgtggagatg aagagccgct aaaagcgaaa cggataatgg
    16741 aacgcatacg ttatttgaca aaagaaatcg aaatgactgg tcgcaaccga cgcaatggtt
    16801 gaacagttga caagtccaac tgacatttga cctagtagta aaagcaggtc agcgaatcat
    16861 tatatggaca gaaatgaccg gagacaatca ccgcaacaag taatgcagaa acttaaacgg
    16921 aggatttttt atgagggcta ttttttctag tatatctgta gttggtctat tttttctttt
    16981 agcaggctgc ggtagcgcag atagcaacac aggttctgtt gattcgattg atgcgggtca
    17041 aacagtaaaa acaagcagta cgaaaacgga gagacaaagc atatttgtcg gaacgattga
    17101 aagtatcact caagtagaag cagaagaaga aacgcttcag ttgaaactcg tcgatgtcat
    17161 ggccaaagaa gatccagcga atatgggaac gtcattcagc aatgacggag tgatcttaaa
    17221 tgctactgct gaaaaaataa gcgtggacat aaatgaattg aaaatcggtg acaaagtcca
    17281 atttacatta gttgagatgc cgatcatgac gatgtctatc ccaccgcaag ttcctggaga
    17341 ttcgattatt gatgtttcat tgaacaaata accaataaca ttttttcaaa aataagaaaa
    17401 tgttgtttta tagaacgaaa aggtatattt tttaaggaga tatgggaatt ttttggctct
    17461 ttgtcaataa ggactgatga gttgtgcaaa atcaaatctg agtcagaatg aaccacattc
    17521 tggctcaga
//
LOCUS       DAMEEU010000060        17151 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.061, whole genome shotgun sequence.
ACCESSION   DAMEEU010000060 DAMEEU010000000
VERSION     DAMEEU010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 17151)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17151)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17151
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.061"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(733..1911)
                     /locus_tag="PB779_002063"
                     /pseudo
     CDS             complement(733..1911)
                     /locus_tag="PB779_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
     gene            1941..2351
                     /locus_tag="PB779_002064"
     CDS             1941..2351
                     /locus_tag="PB779_002064"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739581.1"
                     /translation="MVTLFYRRDFLFSIYTKYFTLSSNIKTSTKLICKLFKLDKISNI
                     DDVKSKILTRKVSEPVKLTAQDKKNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSG
                     EKVTFKINFITAISKLEYGKQKKRDNNDQYLPKK"
     gene            2432..3052
                     /locus_tag="PB779_002065"
     CDS             2432..3052
                     /locus_tag="PB779_002065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739582.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            3753..4037
                     /locus_tag="PB779_002066"
     CDS             3753..4037
                     /locus_tag="PB779_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739583.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            4040..4957
                     /locus_tag="PB779_002067"
     CDS             4040..4957
                     /locus_tag="PB779_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0739584.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            4950..5732
                     /locus_tag="PB779_002068"
     CDS             4950..5732
                     /locus_tag="PB779_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739585.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            5733..6413
                     /locus_tag="PB779_002069"
     CDS             5733..6413
                     /locus_tag="PB779_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0739586.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            6406..7302
                     /locus_tag="PB779_002070"
     CDS             6406..7302
                     /locus_tag="PB779_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0739587.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            7497..9146
                     /locus_tag="PB779_002071"
     CDS             7497..9146
                     /locus_tag="PB779_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HDE0739588.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVASKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            9740..10675
                     /locus_tag="PB779_002072"
     CDS             9740..10675
                     /locus_tag="PB779_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739589.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            10668..11438
                     /locus_tag="PB779_002073"
     CDS             10668..11438
                     /locus_tag="PB779_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739590.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            11854..12837
                     /locus_tag="PB779_002074"
     CDS             11854..12837
                     /locus_tag="PB779_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HDE0739591.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            13284..14321
                     /locus_tag="PB779_002075"
     CDS             13284..14321
                     /locus_tag="PB779_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HDE0739592.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTTRAG
                     SNQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKIL
                     VINGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELG
                     IDQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMF
                     AKTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHML
                     GKVVVSGPFNG"
     gene            complement(14410..14733)
                     /locus_tag="PB779_002076"
     CDS             complement(14410..14733)
                     /locus_tag="PB779_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HDE0739593.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(14720..15427)
                     /locus_tag="PB779_002077"
     CDS             complement(14720..15427)
                     /locus_tag="PB779_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HDE0739594.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            15513..15854
                     /locus_tag="PB779_002078"
     CDS             15513..15854
                     /locus_tag="PB779_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HDE0739595.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(16025..16873)
                     /locus_tag="PB779_002079"
     CDS             complement(16025..16873)
                     /locus_tag="PB779_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739596.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         5461 a         2916 c         3575 g         5199 t
ORIGIN      
        1 aatgaaaaac gagaaggaag atgactttaa agtagtttag tatgaaggtc gattgataaa
       61 acgatgtgga ttaatgctaa ataatgagta atttttcaat aatacaaaaa ctgtgtacag
      121 tattagaagt agagaaacgc tagcgtcgaa aaaaagatat ttttcgtgaa aagtaatagg
      181 ggctaaaaag aaagtataca atttatttat gtttctaagc atataaaaaa gagcgttgaa
      241 aggaatattt ccccttcaac gcttcttttt tagaagattt taatgaccat ctcaacttca
      301 ttttcaggtt taggtaattc atggaagctt gtgtttatcg tgcttaattg atcaactaac
      361 catgttttac tttttgactc gtagacaaat ctaaaattaa tatcattgtt ctcgtgttga
      421 agaggtttct ccaaataatc tggtgaatat tcatagtcaa cgtaacctgc taatacaaaa
      481 gaaagcagtc cattatttag tgtcagattt aacggatggt cgtaagcttt tattttttta
      541 atgtcatatt gtacatctta tgaagactta atgactactt gtagtcaata gatttaaagt
      601 atttattttc tcatttatgt atcaagaata aatactgata taataaaaat tatatcaatg
      661 ttttgatgaa gtaatttgga gggagcgtca ataattttgt gtaaataact cgtccttctg
      721 caaaataatg ggttactcag taaacattga agctaatgta tccgtcactt gttggaagcc
      781 tttatggctt ctatttaaga atttttgatt gtatgtatca aagatggata ctaggaaacg
      841 ctctagtgat tcttcatttt gaaactgctc ttttctgcgg ctgtatttct tgatttgttt
      901 cttgaaagat tcgattaaat tagttgagta aatgcttcgg cggataccag gcggaaactc
      961 ataaaaagtc aataaatctt gattttttat cagtgactgc gtcactttag gataagtttt
     1021 ttgctacttc tcaatcatac tccctaaaaa ggtatttgcc tcttcctttg agctagcttg
     1081 ataaacagcc ttaaaatcat cacagatttc ttttcgatct ttgacacgta ctttatgagc
     1141 aatattacgg gaaacgtgaa cacagcaatg ttggtattta gctttaggat aaatctggtg
     1201 aatcgtatct ttcatgcctt ttaagccatc ggtaataaac agtaagacat catgaacccc
     1261 tctggagtaa atgtcctgta acaactcatt ccaaacgtag gtcgattcag tcggagcaat
     1321 cgcataactt agtacttctt tagtgccgtc ttctcgtata ccaatggcaa tatagattgc
     1381 ttctttggag acggtttgcc gttttaaagg aatataagta gcatccatga aaatagcgac
     1441 atacttatca tttagagttc taactttaaa tgcatttact tcttcagtca gcactttagt
     1501 catgttggac atggtttggg gcgtgtagtg atgcccatac attttctcaa tcaagtctgc
     1561 gatttccgac atggtaatac cttttcggaa gaggtgaatg acggtctcct ctaagatatc
     1621 attcgtccgt ctataagcag gaacagtctg ttgcttgaac tcgccgttgc ggtcgcgcgg
     1681 aatctggaga tgaagttccc cgtactcggt cttgaccgta cggtcatagg agccgttacg
     1741 agaattcccc gtgttaaaac caatgcgatc gtacttttcg taatcgagga aagccgttaa
     1801 ctccgttttg agaagcgtat tgacagcttt ttccaaatgg acacggaata attcattcaa
     1861 atcgcctttg ttcgctagag tctttagaat ttctgtagta aaatcgttca tatggaagtc
     1921 ctcttttctg tgaatgtgtt gtggtaactc tattctacag aagggacttc cttttttcta
     1981 tttacacaaa atattttaca ctctcgtcaa atataaaaac tagtacgaaa ttaatttgta
     2041 aattatttaa gcttgataaa ataagcaata tcgatgatgt aaagtccaag atattaacaa
     2101 gaaaagtaag cgaaccagta aagctaacgg cacaagataa aaaaaatgga attgttcttt
     2161 atggtgatga tgcaaagtat aactataatt gggatacctc ctcagaagct gaggtattaa
     2221 gtattcctac taccgatact tcaggggaaa aagtcacctt taaaataaat tttataacgg
     2281 caatttctaa gttggagtat gggaagcaaa aaaagagaga taacaatgat caatatctac
     2341 ctaaaaaata acgaattaat gatgcatatg ttaaagttgt ttttttgaat taaacaactc
     2401 aatttattca gttatatgtt catcgcagca agtgaacatt aatcgagtta taaaattaat
     2461 aggagctaaa aatataaata aagttcgatc agaatttatt tttccagaag atttttttaa
     2521 ctggtttttt tatcaattca gtgaatgcaa gcgactctta ggtgagaatt attacttaaa
     2581 aggaatcggc ggatttatgg ggaatgtggc tgatgaacaa aatattataa aaggaatatc
     2641 tgaacaaaca tcagagctta cagtaactaa agcatttata agtaatggtg aaagtttgaa
     2701 aaatgtaact gcgcgaatta gaaaagaaaa tgaagtagac attgtttttg gaattgacca
     2761 tgaatgtaat tcagtgatat atgtaacaca atcagcaaat ttaattcttt ttgagaatgg
     2821 ttgcaaggac gattttatgg tggtctattt gtacgatata ctaattccaa aacttcgttc
     2881 cttatatatg tcttctgaaa gtatttttgt gagtgaacaa aagggatctt tctcgaaaaa
     2941 aataggtatt gaagtaattg aatcgattat gtgtcataat catattacgc tagaagaatt
     3001 agaaattttg atagggcaaa aaaataataa cacgaaaata caagtttctt agaaatcatt
     3061 ttttattgag atatctagat aaatgattta ttcttcaatc aaccaactcg ccaagctgag
     3121 gtaatgtttt gaggtaatga taacatacaa ctttttatac cctagtaaaa ctctataaac
     3181 aaagacttat taatttcgca tgaaatacat tcctgtaaaa tgcaataaaa tagagttttg
     3241 tttaaccagg tcttaagaaa gcccgtaaag cttcacagtt ctcaaaacgt taattgcgat
     3301 tatcgttcga gttcacgagt tacgagaatc gtactgggcg aagcaatgct gagcgcagtt
     3361 accttaatcc taacttttct ggcactttcc acaatttgga aagtgccttt tttgtgtttt
     3421 tagctatgtt aataggtagg attcttggtc tataatatca ttcgatctat aaacaaacgg
     3481 gaaaaagata aagtatcatc aaacaatatt atttatccgc ttctgaggtt gtgacagaag
     3541 tggtcagctt caagaaataa gaaggaattt acaaaaattg cttctcatgt ttgataaata
     3601 ttgtgacttg tgaccgagga gttggcagga gaacaccgtt tattcggaag aagggattgt
     3661 gaaaagtctt ttgtcataac ctcttatttg gtagctaatt gtaaatccca aacggcatgt
     3721 attatttttc ataagtccgt ttttaaggat taatgttttc ttttgctttt tatatggtct
     3781 ggcttcagcg agaagttcca acgcatatac aaggacgtct gatgtcaacg ataacaacga
     3841 ttaccatggt ggccagtcca cttggattag cactgtttgg tgcgctcttt gattggcaga
     3901 caactcaacc acgtctgcga gacagtctga tttttcttga aattcaattg gaaaatttac
     3961 actttcttta tacatttctg gctgctttct ttatacccgt caactatact tcacttatca
     4021 ataagaaaga aggataagta tggattttgg aaatgaaacg gtcttgaaag caactggtat
     4081 aaccaaaaaa tacggtgctg ccaaagcatt agataaagta tcgatcgaaa tcaaacgtgg
     4141 aatgatctat ggtttgattg gggagaatgg agcgggtaag tctaccttta tgagaactat
     4201 tatgggtttg atctcgattg atgaaggttc gatcgaatta tttggaacga cggatttgca
     4261 ggcagcaaga cgacgtatgg gtcaatcgat tgaaacccct gctctttatc cagaattaac
     4321 tgcaagagat aacctacgta tccaagcagc gaacggcggt gtgtcggata gagaaatcga
     4381 agacctgctg aaaatgatgc gattggaaaa tacagggaaa aagaaagcaa agaatttctc
     4441 tttaggtatg cgccagcgtt tagctattgc aaatgcactg atcacgaatc cagaattttt
     4501 gattttggat gaaccgacga atgggatgga tccagcaggg atggcagaaa tgcgagaaat
     4561 catccaacgt ttggtaaaag aacggggcat caccgtcttg ctttctagcc acttgctaga
     4621 tgaattgtca cagatcgcca ctcactacgg tattttgcat gaaggacact tgatcaaaga
     4681 attatcgaaa gaagaattgg cacaagaatc tcgtcaattt ataaaaattg acacttcggc
     4741 gacggaacaa gcagtaacgg ttctcgactc tcttggttat agggattatt ttgtccaatc
     4801 tagccgtgtt atccagcttt ttgaaggaat tgaccaagta gcagccatca atcaagcatt
     4861 ggtagaggca aaagttcctg tggatggtat ccacctagtt gggcaaaaac tggaagatta
     4921 tttcttacaa ttaactggag gcaatccaca tgtttaatct attaactgct gaaaaaataa
     4981 aagtatggaa gagccgtaaa atgtgggtct cactaggact gatggtcgta cttccgcttt
     5041 tttattcttg gaacgaatgg tatatgcata caaaatacgg caatgaatta aaccaagcaa
     5101 cggatacagt catcaacggt gcaacaggga ttttaatggt ggaaaaaatg gctgcatgga
     5161 ttcttctggc tttcgcagca tttgcgtgct tttatattgg ggaagaattt caaaacggta
     5221 cgattcgcaa tacgttatct ttaggacgga atcgaatgac ttattatgtg tcgaaacttc
     5281 tcgttacgct tttgatcaca acacttggcg tggttttgat tacggggcta gccatgattg
     5341 cttacacact tgctttcgga tttggtgaag ttgagggaat caaaaactat ggaaattatg
     5401 ttctaaaagt atttcctgta ttgcttctgc tgatattagc gacattatct gttccagtgg
     5461 ctttgacatt catcactaga agtaccagtg tcagtttgct tctttctttt ctttatatca
     5521 tgggaacggc cttcgttccc ggtgttttcg caaaaatcaa aggcttggaa tttctaacgg
     5581 agtggtttac ggaaacgtgg ctcatgtata cggactttgc gcaacaagca acttattcgc
     5641 aagcaccgaa aatgattctg gtcagtctag taacaatcgt ggtatcatca gctctaggaa
     5701 tgtttatttt ccaaaaatct gacattaagt aggtgttcct gctggaaact attttgatta
     5761 tcgaagacga tgaagctgtt cattctttac tggaggaggt tcttgaacag agatacaaac
     5821 ttcttgatgc ttattcaggt acggaaggaa aattattgtt aagcacatat cctgtcgatt
     5881 tgatccttct agatctcatg cttccagggc tttcaggtga agcattgtta gcagaaatcc
     5941 gacagacatc gaatgttccg atcatcgttc tttcagcaaa aagcgatcaa agagataaag
     6001 tttccttgtt ggcagcagga gcggatgact atgtgacgaa accatttgat atcgaagaac
     6061 tgttgttacg aatcggcatc caacttcgtc atcagacttc tgtccaagta aaagatctgt
     6121 cgcaacgcat ctattacaag gaaatcttac tggacaaaga gtcgagggat gtaaatgtga
     6181 atggtgtggc tgtccatttg acaggaagag aattcgatct gctgaagctt tttttagaac
     6241 atccgaaaaa agtattttcg cgagcaaatc tttatgaaac agtttggcaa gaaccatatt
     6301 ttgatagtga gaaaacagtg aatatgcata tttccaatct tcgagggaaa ctagcaaagg
     6361 cacatgctgt gtatattcat acggtgtggg gagtggggtt tagatttgat taagtggctg
     6421 ttgcttctcg ttgttatctt tatgggaagt tttattttct tcctgcaaag ggaaatcaag
     6481 agattaacta agaaaatcgc cactctttct gaacgacaag aatatggtgg tcgtctttca
     6541 gtcgaatttc gagaaaagaa tctaatggac ctagtagatg cactgaatac atgggtggat
     6601 gaaaatgaac aaaaaggaca agcatttcaa gaaatggaag aaaacatcag actatcgatc
     6661 gtcggccttt ctcatgatct cagaactcct ttgactgcta ttaacggtta tgtacaatta
     6721 ctggaacagg tagaggatac ggagaaacgg gagaagtatt taacgatcat caaacaatct
     6781 gttgcaagat tactcagtat gacggatcag ttttatgatc ttgctcgaat agagacgaag
     6841 caaaaagaaa tggatctcca tacgctttct ttttctaaag aggtggaaga agtatttttc
     6901 tctttttatg aacaattttc tgagaaaaat atcgaggtag cgttcgctga acactcgata
     6961 aatacaactg tattagcaga tccgctcatg ttgctgcgag tgctgcaaaa tatcatacag
     7021 aatttattgc gttatgcaga tggacaagca aaggtgacat tttcaaaaga ggattcattc
     7081 attcgattaa cagtggccaa tcctatcaaa ccaggagcgc aaacctctgt tgaaaaagtc
     7141 ttccagcgtt tttataccga aaataccagc cgcacaaata cggaatctag cggaatcggg
     7201 ctttacctgt caaaaaaatt ggtggaagga atgggaggag agatgaccgc tagattagac
     7261 gggggcatct tctccatctc cgtcaagttg cggagggttt aattggctct aatttacctg
     7321 aagtgaatga caaaaaattg tatctcgttt taaagacatc ttcttttttg gaaggtgttt
     7381 ttattttggt gtgattgata cgaattaggt aacgaagaca gttatttttg tacccccttt
     7441 tcaaatagcg caacagtgct atactaaaac taacaaatca aggaacggag agggatatgg
     7501 gccaaagaga atttatcgtt ttaattatta ttgcagttgt tattttatta gttgttttag
     7561 acattttttc gcgtttgaaa gtaaaggaaa cagttcgtag taattgggga aaaattcctt
     7621 atcaaccgag atttgataaa gaagaaagtt tgaaggatgc gtggctcacg gagaaaaaat
     7681 tccgttcatg ggatagtgaa atcgacgatc ttacttggta tgacttggat atgttcgaag
     7741 tatttgaagg gatcaacagt acctattcta gtgtaggttc agaagcgttg tatcagcgtt
     7801 tacgtagctt tgattttgga gaagattatc agttagaaaa actaattgct ttttatcagg
     7861 aaaatcctca actgagagaa agaatccaat atcaattcgc tcgtttagga aaaaaagatc
     7921 ataattttgc aaaacaatat ctagcggatg gaaaaagtaa aaagattgga cgcgtaggtt
     7981 tatttatttt tcttggcttg cttccgctgg tgggtgtagg tttgcttctt ttagggcaag
     8041 tactaggaat ctatctagca atcggtggct tagtattcaa tacggtctat tatctagtga
     8101 agaaacaaac actagaaaca gagctgaata gcatgagtta tttggtttca acgatttcag
     8161 ccgccaatca gttagcaaaa atgacgacac cacttcaaaa agagctgaaa cagcaaacta
     8221 aaccattaag agacatccct aaattaggtt tttcatttcg aatgaagagc gggagtgaag
     8281 cagaattgat ttttgaatat gtcaacatca tgttcatgct gccatttatc tcctatcatt
     8341 tcgttctcac taaattagaa aagcattcaa ctgaagccat caagctgtgg gaattgctgg
     8401 gagaattgga agttgcagca gccgttttga attatcgcac ctatatgccg atcacttgcc
     8461 gaccagagtt tactgagggc ggtgtgacag cgaaagatat ctatcatcca ttgttaaaag
     8521 aagcggtagt taatccagtc aactggcaga agaatacatt agtcacgggt tccaatgcat
     8581 caggaaaatc tacgtatgtc aaaagtatag ccatcagctg tattctagca cagacgatcc
     8641 aaacagcgat tgcagaacag tttaccctgc aacctggaca tgtgttgact tccatggcaa
     8701 tcgaagatga tttatttgaa ggcgacagtt attttgtttc agaaatcaaa tcgatcaaac
     8761 gtttgctgga ccaagtggct tccaaagaac gctgctactg cttcgtagat gagattttaa
     8821 aaggaacaaa tacgatcgaa cggattgctt cttccgcttc agtcgttcgg tggcttgcgg
     8881 agtatccatc tttagcattt gtcgccacac atgatatcga attgacagag attttaaaga
     8941 attattgtga gaatgtccac tttgaagaac aagtaacaga aggaaaagga atcagttttg
     9001 atttcaaatt aaaagaagga ccttcaagga cccgaaatgc gattgccttg ctgaaagttt
     9061 tgaattatcc taaatccata gttgaacagg cccaaaaaga aagtttgttg ttcgatgaac
     9121 agcgtcagtg gtatccgttt gattaacttt atcaaacgaa gcatgatgcg tgggtccaaa
     9181 aagacgatta tcaaaagaag tacattgatg ccaaaaaagt ggcagaattc aatgggaacg
     9241 agtctgctgt ccagatgatc ttggaagatt tagcaaaaga cgatacaaaa taaaccacgc
     9301 tgtcttcctt ctagcagctt ttatcgaaaa aacttagcat cagcgacgag acgcacgttc
     9361 catggcaaag ttctccgtaa aacaaacagc gaaaacagaa attgaaaata actatttcca
     9421 ttttatttat ttcggttaaa ataaaagaaa aaagctttcg ataaaaggac ggaggaaagc
     9481 ttaacatgaa taaaaaagac aagaacctca gttataagga tcttctatat gtcatcgtag
     9541 tagttgctgt cggtactttt atgattttaa aagttccaga gttgtttaga tagttattct
     9601 atcgaagatg atcatgaact agaaaacaca tctcctcttt gttagcaggt gtgtttttgt
     9661 gtggaagcca agttgttttt tcatctgctg tattccatga tacaattaag aatcatgtct
     9721 ataaggagat aggaaataaa tggcaaatgc gcttgaaata aataatttga aaaagatcta
     9781 tggaagtggg gtcgaagcat tgcggggaat cgatctttcg gtgaaagaag gagatttcta
     9841 tgcgctatta gggccaaatg gagctgggaa gtctacaacg atcgggatta ttacttcttt
     9901 agtcaataaa acatctggaa aagtgaatgt cttcggttat gatctggaca aggatctagt
     9961 tcgagcaaag caacagattg gattggttcc acaagagttc aattttaacc cttttgaaac
    10021 ggtccagcaa atcgtcgtga atcaagcagg ctactacggt gtctctcgca aagaagcgat
    10081 gaaacgcagc gaaaaatatt tgaagcagtc caatctttgg gaaaagagaa atgtccgtgc
    10141 acgtatgctt tccgggggaa tgaagcgaag actgatgatt gctagggcat tgatgcatga
    10201 accacgtttg ctgatcttgg atgaaccaac agcaggagtt gacatcgagt tgagacgcga
    10261 gatgtgggag tttctacgag aattgaacga aaatggtaca acgatcattt tgacgacgca
    10321 ttatctagaa gaagctgaaa tgctttgtcg caacatcgga atcatccaat cgggtgaact
    10381 gatcgagaat acaagtatga aagagcttct gtcaaaactg caatttgaaa catttatctt
    10441 tgatttagcg ccatatgata ccaaacctgt gattgaagga tatgcttgta catttgaaga
    10501 tgagcagaca atcgctgtcg aagttgaacg aaatcaaggg gtgaacggaa tcttcgatca
    10561 gcttacaaga caaggaatca aagttctttc tatgaggaat aagtcgaatc gtttagaaga
    10621 actgttcttg aaaatcacag aagaaaataa tcatacggag gagaaaaatg tttaatcttt
    10681 attttactgc attaaaaagt ttagctatca aggaaacgaa ccgctatttg cgtatatggg
    10741 tccaaacact ggttccgcca gtgatcacga catccttgta ttttgttatt ttcggaaaaa
    10801 tgatcggtgg gcggatcggt gacatgggtg gtttttcata tatggaattc atcgttcctg
    10861 gtttgattat gatgtctgct atcactagtt cgtatgccaa tgtttcttcg tccttcttct
    10921 ctcaaaaatt tcagaaaaat atcgaagaaa tcttggtagc acctgttcct acgcatgtga
    10981 ttatttgggg ctttgtgatt ggtggtgtgg gtcgcagtat tctcgtcggc tctctcgtaa
    11041 cgatcatttc cttgttcttt gtaccacttc atgtgtattc atggttcatg gtcatcatta
    11101 cattattgat gacggcaatc ttgttttcat tagcaggact gctcaacggg atttttgctc
    11161 agtcttatga tgatgtatcg atcgtgccta catttgtctt gcagccgtta acttatctag
    11221 gtggcgtttt ctatgccatc tctatgttac cgcccttttg gcaagctgtt tcaaaagtca
    11281 atccgatcgt ttatatgatc tccggtttcc gttacggatt ccttggaacg atcgatgtgc
    11341 cagtagcaac atcgatgatc gtacttgtgt tattcatcgt tgttttgtac gccgttactt
    11401 ggtatttgat caataaagga agaggattga gaagttagaa aagaggttgt gaaatcagcg
    11461 ttttgacctg agtattagag aaacaaacgg gaaaatagtt cctcatattt tgttgttttt
    11521 tgagcgaata ccgagggtca gctgattgaa caccgtttag tggagaggtt gtgaaaaagc
    11581 tgttctgcat caagtaataa gaacagccaa acaaaaatag ctcctcctat ttttcgtttg
    11641 gttggactta ttaccgcaga tgcaagcttt tgaacaccat ttattccgga aaatggactg
    11701 tgataagatt tttgtcacag tctttttttt gctcaatcag aaacatcttt taagctgttc
    11761 actttgcttc tttttttgtt tcctagtata atgacaatgt ttttgagaaa gattgcgact
    11821 tcactgcttg atagaatgga gagtaacaaa taaatgacta ctaatttttg gaaagagctg
    11881 ccaaagcctt tttttgtttt agcaccaatg gaagatgtaa cagatgttgt atttcgccat
    11941 gtcgtaaagc atgcagcagc accggatgtc ttctttactg agtttacaaa ctcagacagt
    12001 ttctgtcatc cagatggaaa agacagtgta cgaggaagat taacatttac agaagatgaa
    12061 cagccgatgg ttgcccatat ttggggagac aagccagaat tttttagaga aatgagcatt
    12121 gctatggcag aaatgggctt ccaaggaatc gatatcaaca tgggctgccc agtccctaat
    12181 gtagcagaac gtggaaaagg cagtggcttg atccttcgtc cagaagtagc ggcacaattg
    12241 attgaagcag ctaaagctgg cggtttgcct gtcagcgtca agacgcgtat cggctatacg
    12301 gaaatgtctg agatggaaga atggatcagt cacctacttc atcaagatat agccaatctt
    12361 tctgtccatt tgcgtacgcg taaagagatg agtaaagtag atgcacattg ggaagtcatt
    12421 cctaaaatca ttgctttacg tgaccaaatc gctccacaaa cactaatcac gatcaatgga
    12481 gatatccccg atcgccagac aggagaagaa ttggccgaga aatatggcgt tgatggcatc
    12541 atgattggcc gagggatttt caagaatcct tatgcatttg aaaaagaccc gagggaacat
    12601 acagaaaaag aactgatcgg actacttcgt ctgcaactag atctgcaaga tcattattca
    12661 gaaatcatcc cgcgttccat cacaggacta catcgtttct ttaaaatcta tatcaaagga
    12721 tttccaggag caaatgactt gcgagttcag ttgatgaata cgaaatctac tgatgaagta
    12781 cgagagatct tagagacctt tgaaaaagaa catccaacgc ttttcagtga acaatgattt
    12841 cttgcttgaa caccgtgaat tagaggtcgt gaaaaagctg tcctgtatca agtaataaga
    12901 acagccaaac aaaaatagct cttcatattt tgtcgttttt tgagctaata ccgagggtca
    12961 gttgattgaa caccgtttat atcagaggtt gtgagcctgc cgtttaactc tgagtcacaa
    13021 ggagcaattt caaaaaacag cttctcatgt ttgatgaata ttttgacttg tgaccgaaga
    13081 gttggtagga gaacaccgtt tataagaggt tgtgacaaaa gtcttgtcgc aacctctttt
    13141 ttaaccaaaa aagtgcaaat agtttacttt aagtaagaga ataattatga tgaataaaaa
    13201 aggtggaaca aatagcatac tatatatatt gaaatgaaca ctgtatggat gctccaactt
    13261 gatgaagcta aggaggaatt cgtatgtcag aaaaggaatt aatgaaggta gtcggttttt
    13321 atgaagggtt gccgatcgat gatccaaaaa gctttattga tgaaaaagaa cagatacctg
    13381 tacccagttc acgggatctt ctggtaaaag tcaacgcagt atctgttaat cctgtcgata
    13441 cgaaacttcg ccaagataac gggataagaa atgctttacg tatcttaggt tttgatggag
    13501 tcgggaaagt tgttgctgta ggtgacgaag tgcaaaaatt ttctgtcggc gatcgcgttt
    13561 tttacgcagg tacaacaaca agagcaggaa gcaatcaaga ataccaacta gttgacgaac
    13621 gtattgtcgc tcttgcacca aaaaatcttt cagatgaaga agctgcagcc ttgccgttga
    13681 cctcattgac cgcttatgaa ttgttatttg aaaaatttgg tctaactcca gaagaaaatg
    13741 ccaatcgcgg gaaaaaaatc ttagtgatca acggatccgg gggcgtcggt tcgattttga
    13801 atcaactagc gcattgggct ggcctagaag tctacgcgac tgcaagtccg aagaattttg
    13861 aatggctgaa aaaaacaggt gtagactatc caatcgatta tcatcacgac ttaagtaaaa
    13921 gttttcgtga attaggaatc gatcaagtag agtatgtcgc tgtattattc gatattaccc
    13981 gctactttga tcaaatcaag caccttgtcc gaccatttgg acatgtggga acgatcgtag
    14041 ggatcaaaga gccgttagat ataggtgttt ggaaaaacca atctatcagc ttcgactggg
    14101 agtatatgtt cgctaaaaca gactataact atgaaatcga aacgcaagga gaagctttag
    14161 cgcacattgc tgctttagca aatgaaggga ttatccgcag tacattgagc aaggtctatt
    14221 cagatgggat gaatgcgaag aacttgaaac aagcaaccaa agacgtagaa acaggacata
    14281 tgttaggaaa agtcgttgtt agtggtccgt tcaacggata agcaagaata cgccgatttt
    14341 tttcttattt gactttgata aaaacaagag cgcatgacag taatttgcca taagctcttg
    14401 tttttttatt tataataagc gaatcaacga aagggaaaga attcctgcca agacgatcac
    14461 caataagctt tttgaaagaa tagcagctaa aagtgtagga actgaagcca aagcattttc
    14521 gagattgatc tgcggcagat gtccgatatt ttgggtaaat agactgctga accataaagc
    14581 agacataatg acgatcggga caaaacttaa atactcaagc aacggttgcg gtaaatcgaa
    14641 ttttttcagt aagacaaatg gtaggaccct agaaagccaa gttgctaaag tacaacctaa
    14701 aatagtcagc aatgtaaact caaaagaagg catgtttgat ccacaccccc aatccgcacc
    14761 caatcagtgt tacaactaca atcactaagt tgcttgggat aaaaatcagt ccgacatata
    14821 ccagaatcaa agtgagacca atcaggatca actgtaatcg tttagaggtg tttctatcag
    14881 aaatgacttg aagataaagt aacccgataa acatagcgac gatggcgaaa tccaaaccaa
    14941 actttttcgg atcagtaata aaattcccta aaagtgcgcc aacaagagaa gaacccaccc
    15001 acgtcaaata agaaatccaa ttagctgtat tcatccaacg aaagtttaac ttttgtccag
    15061 tatagttcaa tttattcatt cccagtgcga aactttcatc tgtcagcaat gtgccaatca
    15121 gcagattttg aagcagccga tttttcttga aataaggagc aatcgtcata ctcatcagaa
    15181 tcattcggga attgactaga aaggtcgaga aaacgatgga aagcaatggg ctgtgactag
    15241 caagcatgct gactgtgata aattgggcag aaccagcata gaccagcagg gacatcaacg
    15301 tgacgactag tggatgaaat ccggcagctt tcccaacgat accaaatgca agtccaatac
    15361 cgatataacc gaaaacggta ggtaacgtgt ctttgatcgc agtttttata tctaactttt
    15421 catccaataa caaaactcct ttagcacgac ataaattttc ataattgtcg ttaaacttgt
    15481 gaatattcta aatttttaat gagcatttgt caatggtggg attgaaacgt aaagaactag
    15541 cgggtcgcag atttacacgt attgtttcgg tgggaggagg cgcgaaaaat cttgcatggc
    15601 tacaaatcca agctgatatt ttcgatgcaa cggtctattg tttaagtgtg gaggaaggac
    15661 ctgcattagg cgcaacaatg attgctgcac tagggttagg gtggttcgac acacctgaaa
    15721 gttgttgtca gaattttatc caatatacag atgcagtgga acctctctta caaaatgtag
    15781 aaaagtatca taaaatctat caacaatgcc ggaaaatcta tccagcaacg aaggaaattt
    15841 gtcatgactt ataaaacaaa acgcgtacct aatagtcaaa tgactaatat tgggtacgcg
    15901 ttaagtcttc tttacttcat cctttgcatg attcgtgttt ttaaagcaag gtctgctgta
    15961 tttcttgtgg atttaggatg gttgttatcg tttacttgct atttttcatt gaaatcgtct
    16021 ttctttaccg tttctttagt tttttatcta tttttttctt ttggttagaa aattcttttt
    16081 cccgaaagtc ttctttcagg atttttatag agtagcgttt tgaataagag gcgtcagtat
    16141 gatcgacttg gcagacgaac caagagaaca tttgcctttt ttctgcatga ggtgcttctg
    16201 ctaataattc tttccataaa taataacagt cctctatcag aagaagggtt cgttcatcct
    16261 caggctccca atagaatgtt tcgagagtag caatcacttc attgatcaat tcgaatgcgg
    16321 gaagataggc attttgctga ataagcgatt caactgcttc ttggatgaac tttcgcatct
    16381 ccatgatgaa cttcgctgtt ttcctgtttt tgtttttctt gataatatga tcgtatttat
    16441 ggatgatagt tgttaattta tctgaataat ttattgcatg aaatggcatc ttaactttga
    16501 agcgttcgat aaagtgcgga tgttctataa gaatctctgt taaaagctcc cgtacaagag
    16561 aggaactagc ggaggaaaca agggacgaga gttcggaaag tgagtagttg gattttttta
    16621 ttggacgttc ttcgtaagcg aataagacag cagccatgtg tttgcatttt tttccttcta
    16681 tggcatatag acaatcacaa gtcatgttgg tcttttcatc ccaagtgatc actaccttat
    16741 aatcttccgt gccagaaact gttgcggaca agtacttgct tgtatagttc aaatgacgga
    16801 caaaaccgtg cagatgatag ctgtaaccgc gttccaaaac gttttcagga aaatactcaa
    16861 gccaattatt catctagttc tcctttcatg aaacacttat ttatatttag tataaagaaa
    16921 cgtttaagaa aaaagtagct gattttacat atttgataat cacttttgct cgaattgtca
    16981 aaaattcatt ctccttttct tttcttagag aatgtgagaa aaagtaaaag aatagcgtgt
    17041 tttaaagatg gaactttttt tgttttttat ttatctgaca aaaatgaagt gattttgtta
    17101 gaaataaata attgttccaa ttgataaaag aggtatgatg tatcgcaaag a
//
LOCUS       DAMEEU010000061        16640 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.062, whole genome shotgun sequence.
ACCESSION   DAMEEU010000061 DAMEEU010000000
VERSION     DAMEEU010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.062"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..174)
                     /locus_tag="PB779_002080"
     CDS             complement(<1..174)
                     /locus_tag="PB779_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDE0739597.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYL"
     gene            complement(176..373)
                     /locus_tag="PB779_002081"
     CDS             complement(176..373)
                     /locus_tag="PB779_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HDE0739598.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(767..2494)
                     /locus_tag="PB779_002082"
     CDS             complement(767..2494)
                     /locus_tag="PB779_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HDE0739599.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2487..3680)
                     /locus_tag="PB779_002083"
     CDS             complement(2487..3680)
                     /locus_tag="PB779_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HDE0739600.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(3867..4511)
                     /locus_tag="PB779_002084"
     CDS             complement(3867..4511)
                     /locus_tag="PB779_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739601.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4605..4739)
                     /locus_tag="PB779_002085"
     CDS             complement(4605..4739)
                     /locus_tag="PB779_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HDE0739602.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(4741..6873)
                     /gene="feoB"
                     /locus_tag="PB779_002086"
     CDS             complement(4741..6873)
                     /gene="feoB"
                     /locus_tag="PB779_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HDE0739603.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFVMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(6870..7343)
                     /locus_tag="PB779_002087"
     CDS             complement(6870..7343)
                     /locus_tag="PB779_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HDE0739604.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            7744..7968
                     /gene="nrdH"
                     /locus_tag="PB779_002088"
     CDS             7744..7968
                     /gene="nrdH"
                     /locus_tag="PB779_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HDE0739605.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8127..10286
                     /gene="nrdE"
                     /locus_tag="PB779_002089"
     CDS             8127..10286
                     /gene="nrdE"
                     /locus_tag="PB779_002089"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HDE0739606.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10336..11301
                     /gene="nrdF"
                     /locus_tag="PB779_002090"
     CDS             10336..11301
                     /gene="nrdF"
                     /locus_tag="PB779_002090"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HDE0739607.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11390..12529)
                     /locus_tag="PB779_002091"
     CDS             complement(11390..12529)
                     /locus_tag="PB779_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDE0739608.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(12838..13551)
                     /locus_tag="PB779_002092"
     CDS             complement(12838..13551)
                     /locus_tag="PB779_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HDE0739609.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(13805..14506)
                     /gene="nagB"
                     /locus_tag="PB779_002093"
     CDS             complement(13805..14506)
                     /gene="nagB"
                     /locus_tag="PB779_002093"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HDE0739610.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            14740..16272
                     /locus_tag="PB779_002094"
     CDS             14740..16272
                     /locus_tag="PB779_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HDE0739611.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16463..>16640)
                     /locus_tag="PB779_002095"
     CDS             complement(16463..>16640)
                     /locus_tag="PB779_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0739612.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5165 a         3428 c         2876 g         5171 t
ORIGIN      
        1 tagataattc accaatctat ttattaaagg actgggatct aattcatatt tttgtttttc
       61 taattttaaa tatacctttt gtaaaacctc aagaatatca gaatatttag gatctttact
      121 tatagatata tcattatata attcatgaac aatttgctta gcattttttt tcattttagc
      181 acttccctgg aattgctcca cctaaaaaac cacctataga cattcctgca atacaagtag
      241 ttgccttggc ccaatcgacc gtacatttat ttttagtgca atacactcca tttccataat
      301 attttccact atgagtggta cccccataga taagttgtgt ctctttaata gacaaaattt
      361 ttaaatgttt cataatctaa tcacccctaa attaatgttt ttagactatt attctaacat
      421 tcattaaatt tcaaaaaaca attccttctt gaaacgtagc aaaataattc ctgaataaga
      481 atttaatcac ttttaagtat ataaactatg tatattcttt aatatttttt gagaatgcac
      541 ttcgtacata ataaacttta atcacattag tctttcatac ctacgatcga tctctttgac
      601 tcgcacccat aaattcataa tagtttgtcg gcgtctttga acgtttcgaa gatgagctac
      661 gcattctctt tttttataga caaaaaagat agagacgaac atggagcttc caaatttgga
      721 tatttgatcc aattttggaa gctccattta tttcgtgtct gtctttttat tttttccagc
      781 tttcgactaa ttcttggttc tctttgatcc agtcttttgc tgcttgctgt ggatcttttc
      841 cattgttgat ttccaacata actttttcca tatctttttc tgaccaatgg aaattgtcta
      901 atactttgta agcttctggc tggtcttctt tcaatccttt tcgaaccatc gtatggatct
      961 gctcttcgct tcccattccg ttttcaggat cttctaagta tttcagatca tatttggcaa
     1021 acatccaatg aggtgtccat cctgtaacta caattggttc gtgttttttg atcgcttgac
     1081 ctagtgcaac ggtcattgct cctgaagaag atgtctctac tttccagtct ttcaagttgt
     1141 catatttttg gatcgtgttt tcagcagccg taactacacc agctcctggc tcgattccta
     1201 tgattttctt acctgcctga tcggttaact catcgatcga atttacatcc atgtaggctg
     1261 gcactgctaa accaactttt gctcctgtca aattggcacc taggtcttcg acttgatctt
     1321 tatattgtgc atattgtgaa ccatgagttt taggtagcca agctgaaacc atggcatctg
     1381 actcgccatt tgaaacagat ttccacatga ttgaattatc taatggcgtc atcgttacat
     1441 catagcccat ttgtttcaat acttcaccga ctacatttgt tgaagcaact tctgtatccc
     1501 attcaacata agataagttg atacgttttg tttctttggc agatgaaaaa ctccctatac
     1561 caatcgcacc taagatcact actactacag caccaatgat cagtccttga cgttttttac
     1621 ttttctgtgt tgttgctcct gcagcttttt tattgtttgg ctggttcaaa tgctgtgtaa
     1681 aacggtcaat gatgattgct aagataacta atgcaacccc gttgacaaat ccattcccga
     1741 cttgtgctct ttgcaatgct gataatacgc cgcgtcctaa gccgggtgca ccgatcatag
     1801 aggcaataac gaccattgaa agtgacagca ttgttgtttg attgatccct gccatgatcg
     1861 tacttttagc taaaggcaat tctagtttga atagtttttg acgacttgtg ctcccgaatg
     1921 aatcagaagc ttctactaat tctttaggaa cttgtcgaat ccctaaattc gtaaaacgaa
     1981 cggttggtgg cagagcaaag atgactgagg caaatacccc tggaaccatc ccgataccga
     2041 aaaatgcaac tgctggaatc aaataaacga atcctggcat tgtctgcata aagtcaagga
     2101 tcggtttgat aatactttgg gctttactgc tttttgccat caagatccct aatggtaccc
     2161 caatgatgat cgagatcaca ctagataaaa gaacaagtgt gacagtattc atcaaatcat
     2221 tccatagacc ttggttataa ataaaccata gaccgattaa tgtgaacaac gtaagtcctg
     2281 gacgtttctt agaaataaag aaagctgcta ccgtcaataa caagataaac aaaggagctg
     2341 gaatcactaa cagtaaattt gtaatccccg acatcactgc ctgtccaatc gtttgtaaaa
     2401 atgaaaatag gccagaaaaa gttgtcgtaa accattctgt gatattttct acccagtttg
     2461 ccactggtaa ttgatagttc aatagattat tcatgttcac tcacctcgct tgtttctgct
     2521 aatgcttcaa tcacactacc tcggatgacg acacctttta attttccatc ctctacaact
     2581 gcaagtggag tcggtgagtc ataaataata ttgaaaatat cacttaccac catgtctttc
     2641 ccaatcaccg tcacattttc atctaggaag tcgatcaatg gacgtttttg cttcctagct
     2701 tctaacgctt gatctgcagt gatgatccct ttcaggtgtc tctttctgtc aacagccatc
     2761 agcatgctga cttcttcatt acgcatcctt gtcaatgcaa cgtttggtcc atcagattcg
     2821 atattcgtcg tcaatgcagg taccatgatg ttttgagccg taagcacttt ggaacgatcg
     2881 acttcttcca caaattcacg tacataatca tttgctggat tggtcaatat ttcttcacct
     2941 gttccgatct gcatgatttc gccgtctttc atcaaggcga ttctgtcccc aatccgtaaa
     3001 gcttcattca aatcatgggt aatgaaaata atcgtttttt gaacattggc ttgcaggtcc
     3061 agtaattcgt cttgcatttc tcgccggatc agcggatcaa gagccgagaa cgcttcgtcc
     3121 atcagcaaga tctcaggatc atttgctaaa gctctggcta ggccaacccg ttgttgcatc
     3181 ccaccagata actgactagg atattggtct ttaaatgaaa gcaaactaga attttctaat
     3241 gctttttctg ctttttcttg tcgttcttct ttaggtacac cacggacttc taacccgtat
     3301 tctgtatttt ccaagatcgt tcgatgtgga aacagaccga agttttggaa aaccatattg
     3361 attttatgac gacggacttc tcgcaattct tctttgctta acttcgatac atcttctcca
     3421 tcaatataga tactgcccga agttggctca atcagacgat tcaatagacg gatcaatgtg
     3481 gatttcccac tcccggaaag ccccatgatc acgaagattt ctccttcttt tacgtcaaaa
     3541 ttcacgtcat acacaccaac cgttgcaccg gttttcttta aaatctccgt tttcggctgg
     3601 tgatcattca tcatatctaa agcggcttgt gtctttttac caaatatctt tgttaaatgt
     3661 tttacttcta cttttaccaa acaaattctc cttttttatg taaattcatt tttctttctg
     3721 aaaaaagtga ccacactatg ttaacatcat gtagtcactt tgtcaaaaat gaaagaaatt
     3781 tgcttgtcca aactgaaaaa aacttggcta aatctttgta aataaaaggt ttagccaagt
     3841 taatattttt ttaatatttc acacaatcat tctgcaagct gatgctccgg gtaaaaaaag
     3901 tttgtcatac gctgtagtgt atattcattt ccaataaaat gaacgatgtc ccctgccgta
     3961 aatttagcat aggggccagg tgaaacaagc agttcttcat tatgagaaat tgcgataact
     4021 gtggcgccag tcgcctgcca gatattcaac tcgctaattg aacggtccag atgcattgct
     4081 ttttctgata aagataattc aaacggaagt aaaggattca tcttatgtat tcgcttcgtt
     4141 tgattgacca gctgatccaa taattgagaa aaatgattca gctcatcttg ttgcttctcc
     4201 acacttgcca tgatttctgc ttttgtatct tggatggatt gtacatcttg atattgcaat
     4261 aggaaatctt ttgctttttc cttcgaagca acaaatgccc cacttccatg ccgtacttcc
     4321 atgattccaa gatctaccag cacattgata gccttgcggg tagtctcagg agaagcattg
     4381 tacgtactgg caagtgttga gcgggcatgg atcttctcac ccactttata tcggttttca
     4441 acgatacgtt cggctaaatc aacagcaatc tgctggtagc gcgggcggac gatttttttc
     4501 tttccagaca ttttctttcc tctttctttt tttactttcc ctcatcttac tatgctctag
     4561 caaaataagc aaaaaagggg agaatagcct cttgcaacga ctgatcatcg cttgatctgt
     4621 tcctttttta ctgggcaagc tgtttgacag tcatcacaat tcttaccgga ttttaaacga
     4681 gtatagacaa ttgcgcctgc acttccaaag attaacacac ttaataagaa tgtcgccatc
     4741 ctattcctct ccttctaatg acaatatagt ataaaactgg ttcttggatt ttggctgacg
     4801 gaacaaaaca taaacgagtc ctatcatcag taaaatagca agatacgtcc ctaacgctac
     4861 ctgtccaccc tccaataagt gtcccaactg ataaatcaca aaactaacta aataagctaa
     4921 accgcattga tagcctatgg cgatccaagt ccatttcttg gcattcattt cccgatggat
     4981 agccccaatt gccgcaaaac aaggcgcaca aagtaaattg aaggctaaca atgaataagc
     5041 tgctgcggga gtatatgtgt gttgtagcac ttgccagatt tctctgccat tttcggatac
     5101 ttccgcatga ccaaacaaaa taccaaatgt gccaataata ttttctttag cgaccaatcc
     5161 tgtaatcgct gcgactgttc cttgccagtt tccccaacca agcggctgaa aaacaactgc
     5221 caggattcgc ccgaaaaagg ctaagatact ttggtcttca gaaacaggtt gagcataaaa
     5281 attataagaa gagctgaacc agatcacgat actagaaaca aagataatcg ttcctgcttt
     5341 tttaacaaaa gacttgctgc ggtcataggt ttgtcttagg accgctgacc attgaggaaa
     5401 atgatatgcg ggcaattcca tgataaaagg agctgtatct ccagcaaaca aacgtgtttt
     5461 tttcaagctg attccagaga aaataattgc agtcatacca agaaaatagg cagaaggagc
     5521 tacccaagat tgatgaggaa aaaaggcccc tgctactaag gcaataatcg gcaactttgc
     5581 agaacaaggc atgaaggttg tgaccatgat cgtcaaacga cgatcttgct cgttttcaat
     5641 cgtgcgactg gccatgacgc ctggcactcc acatcctgta gcaatcagca taggaatgaa
     5701 ggattttcct gaaagaccga atttcctgaa aagtcgatcc atgacaaaag cgatcctcgc
     5761 catatatccg cagtcttcca gaaagctcaa gcataaaaac aatataatca attgcggtag
     5821 aaatcctaac actgctccca cgcctgcgat gatgccgttc aagatcagct cctgcatcca
     5881 tcccgctact tgccattcag ctaacaatct gccaacatgt tctggtaacc atgtaccaaa
     5941 caatgtgtca ttgatccaat ctgtccccat tgttcctact gtttgaatag ccagataata
     6001 gatcagccac atcacaaatg cgaagatcgg caaggctaac caacgattcg ttgcaatctg
     6061 atcgattttg tcactcatcg ataattggaa agaatcattt gacacaacac agagtgtaca
     6121 tagttgggta ataaattcat aacgttcatt gaccagaatc gtctcactat cgtcgtccaa
     6181 tagtttctct gttaactgga tcagttgctc gatctctttt tgctgagaaa ctgctatctc
     6241 gtaatcctct cttaccttct gatctcgttc aaaatatttc attgcatacc agcgtttctt
     6301 gccgctttgt tctcctagta catcttcaat ttcatgtaaa gctgcttcta aacgtggatc
     6361 atatgtacag ggaacaggaa tagaaggccg cttttttgca gactcctgaa tcttttcgat
     6421 tagtttttcg attccttgct ttttcaatac gctgattggt aaaactggta caccaagacc
     6481 ataggaaagc ttttctagat tgattttttt tccttctttt ttgatgacat ccatcatatt
     6541 cagaccaatg atcataggaa tgtctaaatc caataactgc gtagttaaat aaagatttcg
     6601 ttctaaattg gtagcatcaa taatgttgat gatcagttca ggctgttcct gaaccaaata
     6661 atctcttgca atcacttctt ctggtgtata aggagacaaa gaatagatgc cgggtaggtc
     6721 ctgaatatga atgttcggat tttttttcaa cgatccttct tttttttcta ctgttacgcc
     6781 cggccaattc cctacatatt gattcgaacc agtcaagaga ttgaacaagc tagttttccc
     6841 gctgtttgga tttccgacta acgcgatatt cattcttttt cctccctttg tatcaagatt
     6901 agttcggcct ctgactttcg taacgtcagt tcataccctc gcactgtcag ttcgattgga
     6961 tctcccagag gggctagttt tcggataact atttttacat ttcgcgtcaa tcccatatcc
     7021 attaaccgtc gcttcactgc gccttgtccg tggattgcta cgacgatccc agtctctcct
     7081 gcttttaatt gatcaagaga agtccagctt tcagaggaag cagtcttttt attgacaaag
     7141 atttgaccta gtatttcccg acttactgcc actcgatgac tttttaccag taaaatggca
     7201 ttgttgcctg ataaattgac gacgacgatt ttacttccgg caacgatccc gatattttgc
     7261 aaatggcgtt ttgttttttc ttctgtttcg attcgttcga cttgataaac gaaattctgc
     7321 tttgcctgcg ctaaggtctg catattgatt cctctcttgt gaaataaatc atgtattaaa
     7381 atcattcatt atatgttcta attttcttac gtgttacgca aataaatgag aatcattctc
     7441 acatagaata ctctcggtaa ttgagaatgt caattatact tgtgatatta tgagcgaatc
     7501 tttagtattg atagataaaa atgagaaaaa aatatttctt catagttttc cacaattttt
     7561 tctctattaa atttgctatt ttcccacacg atacttgttt tcagctcttt tttcaaaaac
     7621 acaaaactta gtattccaca gtttccacaa cacaatatgt agtgtttgtt gtttgacttt
     7681 tttactaaga gttttatact atctattata gataataaga atgtgttaga ggaggcactc
     7741 accatgaacg taaaaatctt ttctaaaaat aattgtatgc aatgtaagat ggtcaaacgg
     7801 tttttaacag aaaatcaaat tgcttttgaa gaagtcaata tcgatgaaca gcctgaagca
     7861 gtagactggt tgaaagcaca aggattccaa agtgttcctg tcattacttc tgatgcagaa
     7921 acagttatcg gattccgtcc tgatcagttg cgtaaacttg ccagctaaca tgactaaaag
     7981 aatcaaaacg tgatacatgg atttgaaggg cttgagacag caccagtttt tgtcgcaaac
     8041 ttccaaatcc ttttttaaag cttaaaaaca atgcaatgat ttgcaatcaa gcatcatcaa
     8101 atacgaaatg aaggttgggc gtacgtatga gtcttaaaaa tttacaagat gtcagttatt
     8161 tcaagctgaa taatgaaatc aatcggccag tcaatggtca aatccctttg aataaggata
     8221 aagaagcttt agttgccttt tttgaggaaa atgtcaaacc aaatacgatg acttttccat
     8281 ctattatgga aaaaatcaat tacttgatcg atcaagaata tatagaagca gaattcattc
     8341 aattgtattc accatcattt attgaaaagc tatatcaatt tttggacgag caacattttt
     8401 ctttcaaatc ttttatggct gcttacaaat tttattctca atatgcgttg aaaaccaacg
     8461 acggttccgc ttatctggaa acttatgaag atcgagtagc cttcaatgcg ctttactttg
     8521 cgaacgggga tgaagaatta gcacttgctc ttgcagacga aatgatccat caacgatatc
     8581 agccagctac accttctttc ttgaatgctg gacgtaaacg tcggggcgaa ttggtgtctt
     8641 gtttcttgac tcaagtcact gacgatatga actctatcgg gcgctcaatc aactctgctt
     8701 tgcaattgtc ccgtattggt ggcggcgtag ggattacttt atcaaatctt cgtgaagccg
     8761 gcgctcctat caaaggatat gagggtgctg caagtggtgt cgttccagtc atgaaattat
     8821 tcgaagatag tttcagctat tctaatcaat taggtcagcg tcaaggagct ggcgtggttt
     8881 atttgaacgt tttccatcca gacattattg ctttcctttc agcaaaaaaa gaaaatgcag
     8941 atgaaaagat tcgcgtaaaa actctttctc ttggcgtgat cgtacctgat aaattttatg
     9001 aattgacacg taaaaacgaa gatatgtatt tatttagtcc atatagtgtc gaaaaagaat
     9061 atggtgtccc attctcttat gtaaatatta cagctgagta tgatcatcta gttgcaaatc
     9121 caaacattcg caaacaaaaa atcaaagcgc gtgatcttga aaatgaaatc tcaaaattac
     9181 aacaagaatc tggctatcct tacgtaatca atattgatac agcgaaccgc gagaatccaa
     9241 tcgatggcaa gatcatcatg agtaatttat gttcagagat tttacaagtt caaacgcctt
     9301 ctgtgattaa cggcaaacag gaatatgaag tattaggaac agatatctca tgtaacttag
     9361 gctcgacaaa tatcgtgaat ttgatgcaaa gccctaactt tggtcaatct gtgcgtacga
     9421 tgactcgtgc attgacattt attacagatg catctgatat cgatgtcgta ccaccgatcc
     9481 aaaacggaaa taagctgaat catacgattg gattaggtgc catgggctta cacacttatc
     9541 ttgcaaaaga acaaatggaa tatggctcag aggattcatt agactttaca aatatttact
     9601 tcatgctgtt gaattattgg acacttgttg aaagcaacaa tatcgctcgt gaaagaaaac
     9661 aagttttcca taattttgaa aaatcagctt atgctgacgg cacttatttc gaaaaatacg
     9721 taactggaga attccagcca aaatcagaaa aagtcaaagc attgtttgaa ggcattttta
     9781 tcccaactgc tgaagattgg aatgctttga aacaagcagt aatgaaagat ggactgtatc
     9841 atcaaaatcg cttggcagta gcaccaaatg gctcaatttc atatatcaac gatacgagtg
     9901 caagtattca tcctatcact cgcatgatcg aagaacgcca agagaagaaa atcggtaaaa
     9961 tttattaccc agcgccttat ctatccaatg agacgattcc gtattacact tctgcttatg
    10021 atatggacat gcgtaaagta atcgatgttt atgcaacggc acaacaacac gtcgatcaag
    10081 gcatgagttt gactttattc atgcgttctg aaatcccaga aggcatttat gaatggaaga
    10141 caacaacgaa gcaaacgaca cgtgatttga atattttaag acattacgct ttccacaaag
    10201 gaatcaaatc catttattac gtacgtacct ttactgatga tgcagaagaa atcggaagca
    10261 atcaatgtga aagctgcgtg atctaatatc atagatagat tcgcttattc atattttaat
    10321 taaaggagca ttctcatgtc agaaacatat tatgaagcaa taaactggaa tgaaattgaa
    10381 gatatcattg ataaatccac ttgggagaag ctgacagagc aattttggct agatacacgt
    10441 atcccacttt caaatgacct agatgattgg cgtacattgt ctcaattgga aaaagataca
    10501 gtaggacatg tatttggcgg tttgacactg ctagatactg tccaatctga aagtggcatg
    10561 gatcagttgc gtaaagatgt ccgcactccc catgaagaag ccgttttgaa caatattcaa
    10621 ttcatggaat ccgttcatgc caaaagttat tcttctattt ttagtacact gaatacgaaa
    10681 aaagaaatcg aagaaatttt tgactggaca aatacgaatc cttatctgca aaaaaaagct
    10741 gagcgtatca atgaaatcta caaacacggt acaccgctag aaaagaaaat tgccagcgtc
    10801 tttttagaaa cattcttgtt ctattcaggt ttttatactc ctctttatta tttaggaaac
    10861 aacaaattgg ctaacgtagc agagatcatc aaactaatca tccgagatga atctgtacat
    10921 ggaacctaca tcggttacaa attccaatta ggattcaacg agttacctga agcagaacaa
    10981 gaaacgttaa aagactggat gtacaatctt ctttatgagc tttacgaaaa cgaagaacgt
    11041 tatacagaag aattatacga tccaatcggc tggacagaag aagtcaagac attcctacgc
    11101 tataatgcca acaaagcatt gatgaaccta gggatggatc cactctttcc agatactgcc
    11161 aatgatgtca acccaatcgt aatgaacggg atttcaacag gcacaagcaa ccatgacttc
    11221 ttctcacaag tcggaaacgg ctatttgtta ggtcatgtag aagcgatgaa agacgacgat
    11281 tatttgattg gattggaata aggatttatt ttaattcaaa aatttttcga aaaataaaaa
    11341 gagtttagcg tacagatatt ttaaatgtac actgaactct tttttatgct tattcacttg
    11401 tttcttccag cacttttgga ctgtctaact tttccgaaac atgttccatt cttctcaata
    11461 aatagatttt ccggatattt aatattatcg tcttaatcac tgcatagaca ggtatgcaaa
    11521 tcagcatgcc taatattcct gcgacacttc ctgctccaat caataccaag atgatcgtca
    11581 aaggatggat attcattgat ttcccaaata acaacggctt gatcaaattt ccatctaatt
    11641 gttggatcac taaaatcgac aacgccatat acaaagcttg aaatggagag ataaacaaac
    11701 cgacaatgat tgctggtacc gctccaataa aagggccgac atacgggata atattcgtga
    11761 ttccgcaaat gaccgcaagc aacaagctat aaggctgatc gaatattctc attgccaaaa
    11821 agctcattac accaataatc aaagcatcta agatcgtact gctgatatag gcagataatg
    11881 tttcgtttaa ttcttttacc gtttggcgta actctttacg aatcgctttc ggaaagaagt
    11941 gagacaacgc atcaataaat ttgtgcccat ccttgaacat aaatagcaaa ataaatggaa
    12001 cggtaaataa caaaataaaa aattgcatca taaatgaaat gatttttgag acacttgcag
    12061 ataaactgac taatatgata ttgaacaaat tactaagaga taaatttgct gatgctaatt
    12121 gttcttccaa attgaaattt ttaaactctt cccgctgcgc caattcattt aaccatttgc
    12181 ttgtttcatc tgcatacatt ggcaagctct gggtcaattg aattgtctgt tccattaact
    12241 gaggcactac attcatgaca gttaaaacaa ctaaaatgat tacgaccaaa aacgtcaata
    12301 aaaaaccgaa cactctcggg atccgatgct tttcgagaaa aacaacgatt ggatcgaaca
    12361 tataatagat aaaaccagca acaagcaatg gtaaaaaaat tgccgaaagc attttcaata
    12421 ttggactaaa aatattcggc atttgtaaaa taaagtacac gccgatgatc gtgagtacta
    12481 gctccactgt ccagaaaaat aattttgatt gtttaaaacg tgattgcata catctcctcc
    12541 aaggtccttt gatacttcta ttctatcatt taacaaagag ttacgcgctg agattttcat
    12601 ttgcttaaaa aaaacaaaaa aaataaacat attttaatga gtagacgagt acttaaacaa
    12661 aaacacggtt tggagtagtg acaaaaatta tactgcagtc cctttttcca aataaacggt
    12721 gttcaaaagc ttgcatcttc gtaataagcc cagccaaacg aaaaatataa ggaactattt
    12781 ttatttggct gggcttatta cttgatgtag gacatctatt ttacaacctc agatcattta
    12841 ttgcgcaata ctgactaaat gcaactttgt gatatttttg tgtacggaca actcctcgat
    12901 cacatcggca taagtgagcc cttttggaag atcaatcgta tagatatttt tgtacactcg
    12961 gtagtcatca acgaatttta cgtcaaaatt cacatcttcg attacgatat ttttctcttc
    13021 aaaataatcg gtaagaaaat ctttggtttc ttttctatgg ataaattgga tttctaactt
    13081 tttagtcgta ggtacatgga tcacgcgttt cactactgtg agtgcaatag caatcccgat
    13141 aaaactgatg atcgcaatgg aatagtaacc catgccgatg gcgatcccta atccagcaat
    13201 tgcccataaa gaagcggcag tcgtaagtcc cgtcaccgat tgtttcgtga cgatgatcgt
    13261 tcccgcgcct aagaaaccga caccactcac cacttgagca atcagccttg cttcatctga
    13321 acgaatcgtt ccagcaagct gtggatactc taaagcatct cttaatgcac cactagcgat
    13381 ctcaacttgg atcaatgcaa tgatacatgc tcccatacaa actaaaatat gcgtacgcat
    13441 acctgctgga cgatttttat attgtcgttc aaaaccgatt gctccgccaa atagcatagc
    13501 gatccctaaa cgtaaaataa tctctggaat tgtcaatacc atatcattca tctaaacacc
    13561 ctccagtcca atatatcatg tctgaaagga gcagacaaaa aaagtgcaat ttttacctct
    13621 tacgaaaaaa ggactgtgac aaaatttttg tcatagtcct ttttatgaat aaacggtgtt
    13681 caatcagctg accctcggta ttactcaaca aacggcaaaa tatggggagc tatttttcct
    13741 ttgtcttctc taatactcag gtcaaaacgc tgatttcaca acctctttag cctactattg
    13801 aaaattacaa cttacttgct gcttcttcat cgatgatcac aacaacattg tcgtgatttt
    13861 gcaatacact tgctggcaaa tgattcgtta caggtccttc aatcatccct ttgattgcat
    13921 cagctttgct ttcgccaaat gccatcaaga cgatttcttt acttttcata attgaaccga
    13981 ttcccattga aacagctttt gttggtacat cttctgcttt atcgaagaat cgtttgtttg
    14041 cattgattgt tgattctgtt aagtcaacta ctgaagtcgt tccgtcaaat gaagcaccag
    14101 gttcattgaa accgatatgt ccattttgcc cgattcctaa gatttggata tcgattggat
    14161 gtgcatcgat gatttgatca tactttttgc atgctgcttc cagatcttct gcttttccat
    14221 ctggtacaaa cgtttctttg aatggttttt tatcaaataa ttggacatcc atgaaatgac
    14281 ggtagctttg ttcatctgaa ccgcctagtc caacgtactc atctaagttt acagaagtca
    14341 tttcactgaa atccaaatcg cttgaagtca tttctttata taaagtaact ggtgtgcttc
    14401 ctgttgccaa tcctaatact tttgcacctt tgttcatacc ttctttgatg atttcaaatg
    14461 ctttttttcc gccttcttca gcgtttttta cacgaatgat ttccatagtg attgctcctt
    14521 tatattttgg tatagcccaa ttatagcatt ctttttttct ttttacaata attagtatag
    14581 accaaattgc atttttttca ttttcttgac aataaatagg aatccgtgtt aggtttcata
    14641 agatggttca atcaaacaat ccatgttgca tgaaaaccaa gcaagtgatt cactgtggac
    14701 gctttatgtc tgcagttttt ttatgaaaaa ggagttatta tgagtatact gacattaaac
    14761 aacattaccc agcaatttgg cgacaaaatc ctctatgaag gtgtcgatct gcaattaaat
    14821 gctggcgaac atcttgggct gattggacaa aacggagccg gtaaaagtac attgattaaa
    14881 atcatcactg gtgagatctt accagatgac ggacagatcc attggcaaaa aaatattcac
    14941 aaaggttacc tcgatcaata tgtggaagtc gatgaaacat taacaatcga agaatttcta
    15001 aaaactgcgt acgcaaaaga atacgaaaag gaagaaaaaa ttgcttttct ttaccaaaca
    15061 tatagcgaga ccttcgatga ttccttgctg gaaaaagctg ggaaactcca aacggaatta
    15121 gaccaaggag tgttttatca aatcgacacc ttagttgctg agatgagcag cgggttgggg
    15181 atcgatgtct taggtttaga ttcactgttg aaaaatctaa gtggtggaca acgttcaaag
    15241 gtgattttag caaaactact tttagaaaac ccagatgttc tgatcttaga tgaaccaacc
    15301 aatcacttag atgatcagca tatccaatgg ctgacgcagt ttcttcagga ttttgacggt
    15361 gcgtatatcg tgatttccca tgaccaagaa tttcttgatc agatcaccac ccatatcgca
    15421 gacatcgagt ttggaaagat tactaagtat actggccatc taaaacaagc attgaaacaa
    15481 aaggaacaaa atcgcgaaag ctatttgcgc caatatcatg ctcaacaaaa acaaatcgaa
    15541 aagaccgaag cttatattcg aaaatacaaa gccggttccc gatcaacgat ggcaaaaagc
    15601 cgacaaaaac aattagataa aatcgaacgg ctgacgcctc cagcttcagc aagtaaagct
    15661 gtctttgatt ttccattctc gcctattgtc acgacattag cagtggaaac aactgattta
    15721 gtcatcggat atgatcgacc gctacttgca cccatcaatt tgaccatccg ctttggtgaa
    15781 aatattgcca ttcgaggctt caacgggatt ggaaaatcta ctttattaaa aacactgatc
    15841 ggtgagattg aaaaaataag tggcgatttc cacttcccag ataacacaaa aatcaattac
    15901 ttttcacaag atctgtactg ggaaaatcca ttagaaacac cactacaata tttaagcagt
    15961 caatttccaa aagcgactat caaagaatta cgtcgccaac tagctaaagc agggttagtt
    16021 aatcaattag caagtgaacc tctcactaca ttaagtggtg gggaacaaac taaggtgaaa
    16081 cttgcacagt tgacaatgaa ccaaggtaat ttactgattc tcgatgaacc gacgaaccat
    16141 atcgatcaag aaacgaaaga aagcttacaa gacgggatac agaaatttcc aggaacagta
    16201 atcatcgtct ctcatgaaca agaattttat caagatcttg tgcaacgagt cattgagatt
    16261 gaaccaaaat aaacgtttga ttgaatagtt gaaaaaaagg agctgtgaca aaagttttgt
    16321 cacaactcct tcttctgaat aaatggtggc caattagctg accttcggta ttagctcaaa
    16381 aaacggcaaa atatgaggag ctatttttat ttggctattc ttattacttg atgcagaaca
    16441 gcttttcaca acctcttttc gtctattttt tattttcgag atttctcttt cctttaaaaa
    16501 caactgtttg aaagaagaac gcacatcctt gaaaaacaag cccgctaacc gttacaccta
    16561 accagccata ctgctgccac attgtcgtcc ctagcaatga accagccgca cctccaataa
    16621 agtacataaa cataaataca
//
LOCUS       DAMEEU010000062        16633 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.063, whole genome shotgun sequence.
ACCESSION   DAMEEU010000062 DAMEEU010000000
VERSION     DAMEEU010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 16633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.063"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(6..3680)
                     /gene="rpoC"
                     /locus_tag="PB779_002096"
     CDS             complement(6..3680)
                     /gene="rpoC"
                     /locus_tag="PB779_002096"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HDE0739613.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVKETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(3738..7355)
                     /gene="rpoB"
                     /locus_tag="PB779_002097"
     CDS             complement(3738..7355)
                     /gene="rpoB"
                     /locus_tag="PB779_002097"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HDE0739614.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLFALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            8083..9051
                     /locus_tag="PB779_002098"
     CDS             8083..9051
                     /locus_tag="PB779_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0739615.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            9069..9974
                     /locus_tag="PB779_002099"
     CDS             9069..9974
                     /locus_tag="PB779_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739616.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGSAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            9971..10777
                     /locus_tag="PB779_002100"
     CDS             9971..10777
                     /locus_tag="PB779_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HDE0739617.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            10913..11902
                     /locus_tag="PB779_002101"
     CDS             10913..11902
                     /locus_tag="PB779_002101"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HDE0739618.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMMTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(12219..12743)
                     /locus_tag="PB779_002102"
     CDS             complement(12219..12743)
                     /locus_tag="PB779_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HDE0739619.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            13030..14955
                     /gene="scm"
                     /locus_tag="PB779_002103"
     CDS             13030..14955
                     /gene="scm"
                     /locus_tag="PB779_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HDE0739620.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDT
                     SASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTS
                     ASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDSTDTTSTTSDSTDTSA
                     SSDSTDTTSTTSDSSDSSTTTSDSTDTSASSDSTDTSSTTSDSSDSSTSSDSTDTSST
                     TSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGNKSKRALPKTGSQSNNWITLAGVIL
                     LVIGLRITFMSYKKSKR"
     gene            complement(15110..16096)
                     /locus_tag="PB779_002104"
     CDS             complement(15110..16096)
                     /locus_tag="PB779_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HDE0739621.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(16119..16610)
                     /locus_tag="PB779_002105"
                     /pseudo
     CDS             complement(16119..16610)
                     /locus_tag="PB779_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
BASE COUNT         4783 a         3614 c         3256 g         4980 t
ORIGIN      
        1 aatatctatt ttgtttgatt gttcattgcg tcttctgcag ccatttgcgc ttcaatatct
       61 gaaatactgt agacattttc gcttgctaca ccgacttctt ttggttccat gtcacgataa
      121 cgttgcatac cagtaccagc tgggatgatc ttacctataa taacattttc tttcaaacca
      181 agaagaggat ctttcttacc gcggatcgca gcatccgtca agacacgagt tgtttcttgg
      241 aatgatgcag cagataagaa actatttgtt tctaatgatg cttttgtgat acctagtaag
      301 acaggtcgag aagttgcagg aacgcctcct gagactagcg tattgtagtt ttgatcttta
      361 aagtctgcga tgtctaataa tgtacctggt aagatatctg tatcacctgg atccattaca
      421 cgaactttac gcagcatttg acgaaccatt acttcgatat gcttgtcgcc gatttctacc
      481 ccttgcatac ggtaaacacg ttgtacttca cgaagcaagt agttttcaac agataataca
      541 tcgcgaactt gcaacaattg ttttggatcg attgatcctt ctgtcaatgg tgcaccacgg
      601 tggatcatat cgccttctgc tactttcata cgtgctgtat aaggaacagt atacgtacgt
      661 gtatctgttt ttcctttgat tgttacttct ttggtacgtg ttgcaggatc ttctgagata
      721 tcgatgacat cccctgttac ttctgtgatc actgcttgcc ctttcggatt acgtgcttca
      781 aagatttctt ggacacgagg aagaccttga gtgatatcgt ctccggcaac cccacctgta
      841 tggaatgtac gcatcgtcaa ctgagtacca ggttcaccga ttgattgagc ggcgatcgta
      901 ccaactgctt ctccgacttc aacgtcagag ccagttgcaa ggttgcgtcc gtaacaatgt
      961 ttgcagacac catgttttgt attacatgtg aagacagaac ggattgtcac tgtttcgaca
     1021 cctgcatcaa cgatttgttt tgcgatgtct tcggaaatca attggtttcc tgcaatgatc
     1081 aattcatttg tttcaggatg acgtacttct ttacgggtgt aacgtcccac taaacgatct
     1141 tctaatgatt cgatgatttc atttccctcg cggatggctt ggatttcaag acctcggtca
     1201 gtaccgcaat cttcttcacg gatgattaca tcttgggcca cgtcaaccag acgacgagtc
     1261 aagtaacctg aatcggcagt cttcaaggct gtatcggtca tccctttacg agccccgtga
     1321 gttgagataa acatttccaa gacggatagt ccttcacgga agttcgaaat gattggcaat
     1381 tccatgattc gaccattagg agcggccatc aaaccacgca ttccggcaag ctgtgtaaag
     1441 ttggaaatgt taccacgagc tccagaatca gacatcatga agattggatt tttcgcttcc
     1501 aaaccttcca tcagtttttg ttggatgctg tcttttgcag cattccaaac agcaatgaca
     1561 cgttcataac gttcgtcatc tgtgatcaga ccacgacgga attgttttgt aatagtttca
     1621 acttgtttat gggcattttc aatgatttct tgtttttcat tcagtacact gatgtcagcg
     1681 atccctactg tgataccggc atgtgtcgaa tgtttgtacc ctaagtcttt catacggtca
     1741 agcatcttag aagtttcttt tactttgaat cgtttgaaga cttctgcgat gatgtttcct
     1801 aagtttttct tcttgaacgg taatactaat tcttgctctt tgatatgtgc aggaatatca
     1861 gtaccagctt caacaaagta tttgtccggt gtttggacgg tcaagttgaa gtctgttggt
     1921 tcattcagat aagggaattc aggaggcatg atctcgttga agatgatctt accaactgtt
     1981 gtgatcatcg tacgttcttt ttgccattca gtaaatggtt tttcacctaa tgagttaggg
     2041 ttcacaccga tacgtgaatg taaatgaaca tatccgttgc gccatgcgat aacggcttcg
     2101 ttttgatctc tgaagaccat tccttcgcct tcgcgtcctt cttcttccat tgtcaagtag
     2161 tagttaccta gaaccatatc ttgagaagga gtaacaactg gtttaccatc tttagggttc
     2221 aagatgtttt gagcagctaa catcaacata cgtgcttctg cttgtgcttc ttcattcaat
     2281 ggaacgtgga cagccatttg gtctccatcg aaatcggcat tataagcttc acatacaagt
     2341 ggatgcaaac ggattgcgcg tccttgtact aaaactggtt cgaatgcttg gataccaagt
     2401 cggtgaagcg taggtgcccg gttcagcaat actgggtgtt ccttgattac gtcttctaaa
     2461 acatcccata cttcgtcttc ttgacgttcg attttacgtt tcgcattttt gatgtttgaa
     2521 gctagttcgc gttgaacaag ctcacgcatc acgaatggtt tgaataattc aatggccatt
     2581 tcttttggaa gtccacattg gtacatcttc aagaaaggtc caacaacgat aacggaacga
     2641 cctgagtagt cgacacgttt acctagcaag ttttgacgga aacgaccttg tttccctttc
     2701 aacatatgag aaagagattt caatgggcgg ttacctggtc cagtaactgg acgtccgcga
     2761 cgaccgttat cgatcaatgc atctactgct tcttgcagca tacgtttttc attttgaacg
     2821 atgattccag gtgcattcaa gtctaacaaa cgtttcaaac ggttattacg gttgattaca
     2881 cgacggtaaa gatcattcaa gtcacttgtt gcaaaacgtc caccttctaa ttgaaccatt
     2941 gggcgtaaat ctggtggaat aacagggata acgtccataa ccatccagct tggttgattt
     3001 cctgaagcgc ggaatgcttc taaaatatcc aaacggcgga ttgcacgtgt acgtttttgt
     3061 ccttgtgcag atttcaattc ttctttcaat tcggctgctt ctgcatctag atcaacatta
     3121 tcaagtaatt gtttaatcgc ttctgcaccc atagcagctt ggaattcttg tccatattgt
     3181 tcacgttttt cgcgatattc gcgttctgtc aacaattgtt ttttctctaa attcgtattt
     3241 cctggttcga tgactacata tgaagcaaaa taaatgattt cttccaaagc gcgtgggctc
     3301 atgtctaata caagacccat acgtgaagga atccctttaa agtaccagat atgtgaaaca
     3361 ggagctgcta attcaatatg tcccatgcgt tcacggcgaa ctttcgaacg agtaacttcc
     3421 actccgcatc gatcacaaac gattccttta taacggatac gtttgtattt tccgcaggca
     3481 cattcccagt cttttgtagg accaaaaatc cgctcacaga acaacccttc gcgttcaggt
     3541 tttaaggtac gatagttaat cgtctcaggt ttttttactt caccgtaaga ccagcttctg
     3601 attttttcgg gagaagccaa acctatttgc atactttcga atttatttac atcgatcaaa
     3661 aggggttccc tccatttcat ttaatggcaa accgcaagac ggctgatctt cgaccgcctt
     3721 gcagctcata gaccggatta gtctaaatta tcttctgcgg tttcaaagtt ttggatgaca
     3781 tcgtcttttt catcttccac ttgttcagca gctttctttt ctaattcttt ggcagtttgc
     3841 tgttcggcaa attttgtcaa agcatcaaca gtgatcaaat cgtcgtcttc atcgtccatg
     3901 tcgcgaagtt cgatctctgt ttcttcgata tccaagacac gcatgtccag acctagtgat
     3961 tgcaattctt tcaccaatac gcggaatgat tccggtacac ctggttttgg aattggttca
     4021 cccttgacga ttgcttcgta tgttttcaca cgtccgacta cgtcatctga tttgtatgtc
     4081 aagatttctt gtaaagtata agccgcaccg taagcttcca gtgcccatac ttccatttca
     4141 ccaaaacgtt gtccaccaaa ttgagcttta cctcccaatg gttgttgtgt aaccaatgag
     4201 taaggtccga ttgaacgtgc atgcaatttg tcatcgacca tgtgagcaag tttgatcatg
     4261 tacatcacac cgacagacac acgtccatca aatggttcac ctgtacgtcc gtcgtacaga
     4321 acagttttcg catcgctggc cataccggct tcacgaactg tttcccatac gtcttcatca
     4381 cttgcaccat caaatactgg cgttgctacg tggataccta actgacgtgc agccataccc
     4441 aagtgtaatt ccaatacttg cccgatgttc atacgtgaag gcacccctaa aggattcagc
     4501 atgatatcga ttggtgttcc atcaggtagg aatggcatat cttcttccgg cataatacgg
     4561 gatacaaccc ctttatttcc gtgacgaccg gccattttat ccccttcatg gattttacgt
     4621 ttttgaacga tataaacacg aactaacatg tttacgcctg gtgacaattc atctccagct
     4681 tcacgagtaa agattttcac atcgtgaacg ataccgccgc cgccatgtgg tacacgtaat
     4741 gatgtatcgc ggacttcacg agctttttcg ccaaagatcg catgcaatag acgttcttct
     4801 gcagataatt ctgttacccc ttttggcgtg actttcccta caagcaaatc gccatcttgg
     4861 acttctgcac caatacggat gatacccatt tcgtctaaat cttttaatgc gtcttccccg
     4921 acattaggga tttcgcgtgt gatttcttca ggtcctaatt ttgtatcgcg ggcttctgat
     4981 tcatattctt caatatggat agaagtgtat acgtcatctt ttaccaaacg acggctcatg
     5041 atgatcgcat cttcatagtt gtacccttcc caagtcatga aaccaactaa aacgttttgg
     5101 cctagagcca tttcgccttg ttccatagat ggtccgtctg ccagagtatc ccctttttcg
     5161 actttctcac ccaaatgaac gattggacgt tggttgtagc ttgttccgga gtttgaacga
     5221 cggaattttg ttacatcgta tttatctaat gcaccgttgt cgcggcgtac gcggatttca
     5281 gaagcatcaa cgtattcaac gacaccatca tgtttacata acaaagcagc tcctgagtca
     5341 tgcgctgatt tgtattccat accagtacca acccatggtg cttgaggatt gatcaacggc
     5401 actgcttgac gctgcatgtt ggcacccatc aaggcacggt tggagtcatc gttttccaag
     5461 aaaggaatac atgctgtcgc aacggcaact acttgtttag gtgatacgtc catgtagtct
     5521 actttatcaa tagatacttc taagttttca ctttgagcac gagccataac aacgtcttga
     5581 gcaaatgttc catcttcatt caatgggctg tttgcttggg ctacgatgta atggtcttcg
     5641 atatcagctg tcaagtagtc gatttggtca gtaacacgac ctgtttcacg gtctacacga
     5701 cgataaggtg tttcgataaa tccgaattta tttactttcg cataactgga caaactattg
     5761 atcaacccga tgtttgggcc ttcaggagtt tcgatcggac acatacggcc atagtgggag
     5821 tagtgaacgt cacgaacttc ataaccggcg cggtcacgag tcaatccgcc aggtcctaag
     5881 gcgaaaagac gacgtttgtg tgtcaattcg ccaagagggt ttgtttgatc catgaactgt
     5941 gacaactgag aagaaccaaa gaattctttg atacttgcca caactggacg gatattgatc
     6001 aattgttgag gtgtcaatgt ttcagtatct tggatcgaca ttctttcacg aaccacacgt
     6061 tccatacgtg ctagcccgat acggaattgg ttttgtaaaa gttcaccgac tgaacggata
     6121 cgacgatttc ctaagtggtc gatatcatcg acattgccga taccttccat caagttcaag
     6181 aaatagctca ttgaagcaat gatgtcggct ggacgaaccg tttttacagc tgcttctgga
     6241 tagccgtttc cgatcacgtt tacttcacgt tcagggtctc ttggtgaaaa tactttgatg
     6301 acttggacag tcattggatc tgtgaccaca ccgtcttctg atggatagta agtcactgaa
     6361 tttaggccat tatcaatgaa aggagctagt gtttccatga cttggtgagt cagaactgtt
     6421 cctttttcaa cgatgatctc gcctgtttct ggatcaacta atgtttcagc taatgtcaga
     6481 ttcaatagac gtgttttcaa atctaatttt ttgtttactt tgtaacgacc aacgtttgct
     6541 aagtcgtaac gttttggatc gaagaaacga gcattcagca agttacgtga gctgtctgct
     6601 gtttttggtt cgcctggacg caaacgttcg taaacgtctt tcaaaccttc ttctgttctt
     6661 gagtcgcttg cgtttttatg caagtctttt tcgactgtat tgcgtaatgt ttcgctgtcg
     6721 ccgaagattt caaagatcgt atcatcggaa ccaaatccta acgcacgaac taatacggtt
     6781 aaaggaatct tacgtgtacg gtcgatacgt acataagaga tgtcttttgc atcagtttcc
     6841 atttctagcc aagctccacg gttagggata acagtagaac cgaatccttc ttttccgttt
     6901 ttgtcgactt ttccatggaa atagacacct ggtgaacgga ctaactgaga aacgattact
     6961 cgctctgccc cgttgatgat gaatgttcct tgttctgtca ttaatgggaa atcaccgaag
     7021 aatacttctt gtgctttgat ttcgccagtc tcgcggtttg tcaaacgcaa tgttacatgt
     7081 aatggtgcag agtagtttgc atcatgcgca cgagcttctg ctactgtata ctttggttct
     7141 ttcaattcat aatctacaaa ttccaaagat agattgccat tgaagtcatc gattggcaaa
     7201 atgtcttcaa acatttctct aagtccctca tctaagaacc attggtaaga gtctgtttga
     7261 atttcgatca aatttggtaa ttccaacact tcactgattc ttgcgaaact tctacgttcg
     7321 cgatgttttc cgtattttac tacgtgtcca gccaagctct tcacccctct aaaatgtcat
     7381 tcaaaaagac tacccgatca attgttacaa taatatttca aatattattt ttaggtaaca
     7441 acagacattt tttgcggctt ttaggcaaaa aaaaaccaaa aatagaacat tctcttgaaa
     7501 ccttacttcg tgagcttcta cttttgtttc cttatattaa agccgaaacg gacaatattt
     7561 cgtttctgcc ttttcttcat cagatagttt ttgcaacttc atatactaca cttattttct
     7621 ataaaagtca acacttcctg gcgtttcttc tgctttttcg caacattttc ttaatgtttt
     7681 caattttatg ttttcaatta tctgacaatt cttaattgac agaccttttt atctcggtta
     7741 tactttagaa aattcatttt gtggaggaac ttctatgcga accaacatca accaaatcgc
     7801 accaacacaa ctgaataact tttactttag ctactttaga taggtttgta ttcatcatga
     7861 tggatacaaa cgttaaacga cagtttgtat ctatgatggc taaagaactt tgtattgcag
     7921 caaaaagcca cgtagacaaa atgctaagtg gctgagcagt gaaaatacaa agtaaaagta
     7981 tcaagcattc tactttttca atttattttc cgacttttca atccatttgg acattttgtc
     8041 tgaatggatt ttttgtttcc caaaattaag gaggaaaaag aaatgaaaaa aaatataatc
     8101 atcggattag gcgctgccct gctactagct ttaggaggtt gcgcacaaaa agacaattcc
     8161 gcagaggcat cagatggaca aaaaacaatt ggcgtattgc aacttgtaca acataactcg
     8221 ttagatgctg cctataaagg attcaaagaa ggattagcag aagaagggta taaagaaggc
     8281 gataatctaa caatcgatta tcaaaatgcc caaaacaatc aagacaacct gaaaagtatg
     8341 agtgagaaac tcgtcaaaga agatcctgat ttgctacttg gaatcgccac tccagcagca
     8401 caatctttat taaatgaaac aaccactatc ccgatgactg tcacagcggt cacagacttg
     8461 gaacaagccc atttagtcac atccaatgaa aaacctggcg gcaatgtgac tggcacgaca
     8521 gatatggtgc caatcgaaaa acaaatcggc ttactgttaa atatcgtgcc agacgccaaa
     8581 acaatcggca tcatgtataa caacggtgaa gcaaactcta agatccaagc tgatttggca
     8641 gaaaaagaat tgaaaaaagc gggcgtcaaa gtcaaagtac tgacagcaaa ttccacaaat
     8701 gatgtccaac aagtgacgaa aagtctagct aaagatgtag atggaatcta tattcctact
     8761 gataacacgt tcgcaagtgc ggcaagtgtt gtcggtgaag tcgcaaaaga aacaaaaaca
     8821 cctgtcgttg ctggcgcagt tgatcaagtc aaagacggcg gtctagcaac agtaggaatc
     8881 gactacgaaa gcttgggcaa acaaacaggg atcatggcag caaaaatctt agacggcaag
     8941 aatccaagtg aacttcctgt cgaaacagcg aatgatttgg aactgtatgt caataaagac
     9001 atggccaaag cattaggcat caatccagac agcatcaaag aagctgaata aaacacagga
     9061 ggattctcat gacaaatttg ctctctcttt tcttatcatc tgcatcgcaa ggggtcttat
     9121 gggccctact tgcgattggt gtatacgtca ctttccgtat cttggacatt gccgacttga
     9181 ctgctgaagg aagctttcct ttaggtgcag ggatcgcggc agtaagtatt acaaatggct
     9241 atcatccatt gacagcttgt cttctaggct ttttagggag tgcggcagca gggcttgttt
     9301 ccggactgct tcacacaaaa ttgaaaattc ccgcccttct tgcagggatc atcaccatga
     9361 ctggtttata ttctgtcaca tcccgtgtga tgggtgcgcc gaacatctct ttattgggtc
     9421 agccaacgat ctttcattgg gtcgagtcat tcggcataac aaaagacaac gctgtactga
     9481 tcgtcggtct gctttttgct ttgatcgttg tatgtttact tgttttgttc ttacgtacag
     9541 aaacaggact tgctattcgt gcaactggcg ataatctggc aatgagcgaa gcaaacggga
     9601 tcaacacaga taatatgaag atcatcggtt atatgatttc taatggatgc attgctcttt
     9661 ctggctcctt gcttgcgcaa aacaacggct ttgctgattt aaattctggt attggaacga
     9721 tcgtaattgg acttgcttct attatcatcg cagaagtttt gttacgtaac cagccactat
     9781 ttctccgtct cttgactgtc gttttaggtg cggtcattta tcgttttatt ttagcgttag
     9841 tcttcgaact gaatgttgaa ccaagtgatt cgaaacttgc ttctgctttc gtgctagtga
     9901 tctgtctttc tttcccgcag atccagcaaa aattccattt acctcaaaaa aagaaaggcg
     9961 gtagtgtcaa atgaatgacg tcttaacatt ggaaaatctc catcatacct ttgaaaaagg
    10021 aacgatcaac gaaaatcatg tcctgaaagg cattaatctt tccttagatc ccggcgactt
    10081 cgtgacgatc atcggtggaa atggggctgg taaatctact ttgctgaaca gcatcgccgg
    10141 tacattttct gtcgatcagg gtcaaatttt attgaatgga aaaaatatca cgaaaaaatc
    10201 tgttgtcgaa cgttcgaaat ccatcagtcg cgtattccaa gatcctaaac tagggacagc
    10261 cgttcgttta acggtagaag aaaatcttgc tcttgctatg aaacgaggaa aaaaacgcgg
    10321 cttcttccgt ggtgtcaaac cacaagaccg aacatttttc aaagaccagc tggttcggct
    10381 aaatttgggg ttggaaaatc gtttatcctc agaaatcggt ttgctgtctg gaggacaacg
    10441 tcaagctatt acgttattga tggccacatt acagcgtcca gaactgatct tattagatga
    10501 acacactgca gcgcttgacc ctgctacttc caaaacggtg atggaattga cagaaaagct
    10561 gatcactgag cagaatctca ctgcttttat ggtcactcat gacatggaag acgcgatccg
    10621 ctatgggagt cgactgatca tgctgcatca aggaaggatc gtcgtagata tccagcaaga
    10681 ggaaaaacag cagctcacag tgccccaatt attagcgttg ttcaaacaaa acagcggcac
    10741 ggcattaaaa gacgatcaag tacttttatc ttcataatca gaaagaggat gggacaaaaa
    10801 atgaacgccc accctcttct tttttctctt tccttctttc gtttttgctt tatgtatcaa
    10861 ccgttgtttc ttcgaaaact attttgttct ctccttcttc ctgatagaat ggatgggaaa
    10921 ggagcttgat gccatgacaa cgaaagacaa ggtacttcaa ttattgaaaa agacaccaga
    10981 ttttctttcc ggagaaaagt tggcacagca actggaagtt tcccggacaa gtatttggaa
    11041 agccatcaaa gaattggaaa aggcaggcta tcgttttgag cacgggccta cagggtatcg
    11101 ttacctgccc tctgacgtac tagatgcaaa agaaatccag caagagctac ggtcgtttat
    11161 tcctgatttg aaagtacaaa cgatgatgac ttctgaatct acgatgaaag atgccaaact
    11221 ggcagcagct caaggagatt ctgtttcgaa gttatttgtt gctgatacac aagaacaagc
    11281 tcgtggacgt tttggacggc cttttttcgc tgaacctgga cgaggaatct acatgagtct
    11341 cttgctccat ccagacaaac ggtttgatga attgcctcaa tatacgatca tcgcagccag
    11401 tgcctgtgtg aaagccattg aatctgtaac cggtcgttct gcttcgatca aatgggtcaa
    11461 tgatatctac atggatggaa aaaaagtctg tgggatttta tctgaagcag tcagtgatat
    11521 ggaaagcggc aggatcagtc atatcatcat tgggatcggg cttaattttt ctgttcctca
    11581 aaatcatttt ccagctgatc tccaagaaaa agccatctct gtctttcccg acggacaagc
    11641 tagtgtcaca aggaatcagc taatcagcaa aatctggcaa gaattgttca cttatctttc
    11701 tcacccagaa aaagcgttgg acttctataa agaaaaatca ttcgtattgg gaaaaaccgt
    11761 gtcgttcaat caaaaaggaa cgacttatgt cggtcttgca aaagaaatcg gtgatcatgg
    11821 cgaactgatc gtccaaacaa atgaacagaa gatgagtttg tcttctggcg aaatcagtct
    11881 cacatctatc cgtacgcaat aattatcaga tttcacaaaa ggacacctga tctcatacag
    11941 tgtccttttt tctgaattct cttcaaaaga ctctccttat tctatcagct gacagtttct
    12001 ctatcctcta gaaaaaggta ttctaaaaat atctataaag catggtacac tttctttaaa
    12061 tgaatcaatg caaaaaacaa gagagtcatc agtttacacg atcaaaagag atagcaggcc
    12121 gcttcctttt tcaatcttat agatagacca tgggtaacga taaaaacaaa aaagaacttg
    12181 cgacttattt tgccgtaagt tcttttttag ctagtgcctt aatctcttaa tcccaacaaa
    12241 cgtctcgcat agatcacctg accagagtgc atagcagcat catcaataat agaaacgaga
    12301 cgcattcctc gtgtgactgg tggtgtccag ttctcgtcaa ttacttcatc tagctcggaa
    12361 ggttccagcc ttcttaagta agaaatagca aaatcagcag ctcctcgcaa gtatcctagc
    12421 agatcttcta tttgattagc ttggatctgc tttgcttgtt ccagactatg cttccaatct
    12481 tgttcgttat ctgctatcgt catcggaaac cggctttccc agtcttgact atgccaaatt
    12541 ggagaagttc ctgctaaatc agcaatctgg aaatctaatt ctcgagcggt atgccaagcc
    12601 agccaagtca ttgatttgat ctgcggggct ctatcttcca ctggaaaacg attggcctcc
    12661 tcaatagaga cgccttcaaa caaacgttca aaccgatcgt atgcccgatc cacactctcg
    12721 catagcatat ctaaataatc catttatttt cctccttttt atttatccta cttacttttt
    12781 cctaattcta ggatacctac ttatatgtta ctacacaccc ttatttttta cactttaaca
    12841 gtcaccatca tcaatagttt ggagattgaa agaaaaagat agtgtcgaac tatcaattga
    12901 acaagaagca acaatatgaa cgtttcatta atattcttta aataaacaat gatttttcaa
    12961 acgaacagtt taagactagg agaaaaagag tataatagga aaatgtttga aaggaaagga
    13021 aggggaaaaa tgaaaaaaag ggcaagttta ctagtcctag ttgctttgtt gttcaatatc
    13081 ttttcgtatg gtgtggccgt ttcagcggaa acatacattc ctaaagaccc tgggaatatt
    13141 tataatgatc taactggtaa ctatggcttg ttaggaattg ctagtcaatt ccacgtattt
    13201 gctaaaaata agacaactgt gaatgcacat acagacggaa atatagcaac acatgaactt
    13261 gatgcaaaaa ataattttgg tacagagctt catgaaggtt tattgaacca agaaataaat
    13321 tatatacaaa aaactgattc tttcgctaat tcttcaggca tacctacagg tagcacaaga
    13381 atgaataaat ttgtcgttgg cagtaacgtg gatgtagcac ttcaagatgg tcatcctaca
    13441 gtcaatggat ccaggcttga tcacttaact ccagatgatt tttataaaga tcgtgctggg
    13501 catgaatata ttgatttcga gcaggaattt gctaaattga atgtagcagc aaatgatctt
    13561 gcaacgatca ctccagctaa aacatatact gctgcagatt ttccagacat gaacaatcgg
    13621 acaatcgatt taactgattt atcagatacc gggtttttat tggtaaatat cgatgcagaa
    13681 gtgttaacga tgaatacgcc acttcaaatc attaatccaa atgatcaagt agttgtattt
    13741 aatgtcatca acagttcttc tgcattgaac gtacagtcac caatcaaata caatgatcgt
    13801 tcaaatcatg aaacagaaga tttttcggat gcgaatatct cttggaattt tggaaatgag
    13861 atgactgatt tgacaatcag tgctcctttt caaggaacaa tccttgcgcc taatgctact
    13921 atccgcatta ctcaaaacca agacggaacg attataggaa caaatgtgat tttagatgca
    13981 gctaccaatc gttgggatcc taacgaaata tttatcagcg acaatggtac agatacgaca
    14041 gacacaagcg acagtacaga tacatctacc acaagtgata gctcagattc atcaacttca
    14101 agcgacagta cagatactac ctctaccaca agtgatagca cggatacatc agcttcaagc
    14161 gacagtacag atactacctc taccacaagt gatagcacgg acacatcagc ttcaagtgac
    14221 agtacagata ctacctctac cacaagtgac agcacggaca cgtcagcttc aagcgacagt
    14281 acagatacta cctctaccac aagtgatagc acggatacat cagcttcaag cgacagtaca
    14341 gatactacct ctaccacaag tgatagcacg gacacatcag cttcaagtga cagtacagat
    14401 actacctcta ccacaagtga cagcacggac acgtcagctt caagcgacag tacagatact
    14461 acctctacca caagtgatag cacggacaca tcagcttcaa gtgacagtac agatactacc
    14521 tctaccacaa gtgatagcac ggacacgtca gcttcaagtg acagtacaga tactacctct
    14581 accacaagtg atagctcaga ttcatctacc actacaagtg atagcacgga cacgtcagct
    14641 tcaagtgaca gtacagatac atcctctacc acaagtgata gctcagattc atcaacttca
    14701 agcgatagta cagacacgtc gtctaccaca agcgatacac gtcatgcaag tgtctccttc
    14761 tcaaaaacaa gttcggataa caggacgaac tttaacttaa ctaataaaac aagcaatgac
    14821 aatggaaaca aatcaaaaag agcacttcct aaaactggaa gtcaatcgaa taattggata
    14881 acactcgcag gcgttatatt acttgtaatc ggtttaagaa tcacttttat gagttataag
    14941 aaatcgaaaa ggtaaaaaaa tattcaagat aaaaaagagc aacgtcgcta acggacgttg
    15001 ctctttattt ttgcttttta tcataaatac aagaactaca attcaatttg tcaaaaaaca
    15061 cgtagatttc cttctgagaa atttatttac gtatcgaacc tttccctatt cagtctttgc
    15121 gatccaaaat cagttgggta agggaaaaga gattctcttt tgttcgaaga gaggtggcag
    15181 gtaatttctt tatttccttc aaagcctttt ctgtgtaaga ggccgctaac ttcctagctt
    15241 cttccacgcc tcctgtatgt tcaacgattt tgcgtacggc gtcgacatct tcttctgtca
    15301 ttgccgcttt cttctctaaa taaggtagta gctttggttt gtttttttgc aaagagtaga
    15361 tcaacggtaa agaatagacc ccttgacgca tgtcttctag tacaggtttg ccgatttcct
    15421 ggctctcttt tgtataatct aaaatatcat cgataatctg aaaggccatc ccgatagaaa
    15481 gtccgatatc tcctgctttt tttgcgaagc gctcgcttgt tccactttca aaagcgccaa
    15541 cagaacaact taattggaac agttcagctg tcttacctga aatattttcc aaatattctt
    15601 ttacagaaag ttcataatta tagcgatcat ccatctgccc taattcgcca ttcaatactt
    15661 tttccatact gcgagaattc aattggagac ttttcaagga agtggagtaa tcagacaata
    15721 gtttaaaaca gcagacaaat aaatagtctc ctgcatagac agaaacgaca ttaccaaact
    15781 gactacggat attaggctga ccacgtcgca gatccgcttc atcaacgata tcatcatgga
    15841 tcagtgtggc cgtatggagc atttcgatag aagctgccaa agcgatggct ttgtctcgat
    15901 cttgctctgg tccaaattgt gagaacaata gctgataggc aggacgcaac agctttccgc
    15961 cggcatggat cgtttctttg attgcttgtt cgacaggttt gtttttcagg cggacagttt
    16021 cttccatccg ttttagtgtt tctgtcaatt ctttacttaa agcaggatag ttttcccaca
    16081 ttggatgtag cttcataaaa aaactccttg tgtgacgatt attttttggt aaacattggg
    16141 ctccattttt gtttggttcc ctgctcataa tctttttgga atcgttgaag tgtctgcaca
    16201 tgtcgtaaaa gataattcgc tgcgatcccg attgcaatcc ctgataaaat ccctaaaact
    16261 gaaaggactg gcaagtacaa catgactgtc catgattgtg caatgaaaga agccatcaaa
    16321 agctgtccga cattatgcat gaaaccgccg gccgcactaa ttccgatgat actgacacgt
    16381 tttggtccta attgcttgac caataacatt ccaaaataac taagcaaagc accactcata
    16441 ctataaagga atgtggaaat cgttccgcct agcaaagtag tcaggaatag tcgtagccaa
    16501 agtagtaaga agctgtcttg ttttttcatg gtaaaaatgg caacgatcgt gattagattg
    16561 gctaagccta gttttgcacc aggcgcaaaa gaaaaaggat aagggatcac ccgtggtgct
    16621 agttaatttt ttc
//
LOCUS       DAMEEU010000063        15855 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.064, whole genome shotgun sequence.
ACCESSION   DAMEEU010000063 DAMEEU010000000
VERSION     DAMEEU010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.064"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            14..1141
                     /locus_tag="PB779_002106"
     CDS             14..1141
                     /locus_tag="PB779_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0739622.1"
                     /translation="MAFLFVSLNYTNGEDINDDGSRKKVEKVGGDTRPEAEAALRKVL
                     SDIDETGQYFLGTDTRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKL
                     TDLSPALLQNFINAEFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPK
                     YEARPTTKKDLKIISLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVD
                     FSNGTITVEKQMVKNDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYG
                     KLYIDSNAVCTKEDGELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKM
                     KEISERLGHSRISITMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1359..2501)
                     /locus_tag="PB779_002107"
     CDS             complement(1359..2501)
                     /locus_tag="PB779_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0739623.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGIYLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2506..2691)
                     /locus_tag="PB779_002108"
     CDS             complement(2506..2691)
                     /locus_tag="PB779_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDE0739624.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(3045..3290)
                     /locus_tag="PB779_002109"
     CDS             complement(3045..3290)
                     /locus_tag="PB779_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739625.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3284..3685)
                     /locus_tag="PB779_002110"
     CDS             complement(3284..3685)
                     /locus_tag="PB779_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDE0739626.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="PB779_002111"
     CDS             complement(3872..5680)
                     /gene="uidA"
                     /locus_tag="PB779_002111"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HDE0739627.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KFITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDVCKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWMERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAYYLQKRWSSIPNFSYKK"
     gene            complement(5703..7469)
                     /locus_tag="PB779_002112"
     CDS             complement(5703..7469)
                     /locus_tag="PB779_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HDE0739628.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IITDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIVPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7482..8276)
                     /locus_tag="PB779_002113"
     CDS             complement(7482..8276)
                     /locus_tag="PB779_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HDE0739629.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYSQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGDYVDIEQKYIDTFWKNLTNK"
     gene            complement(8286..9662)
                     /locus_tag="PB779_002114"
     CDS             complement(8286..9662)
                     /locus_tag="PB779_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0739630.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLVIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQYKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKASNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANVQTGDVLEKLYNASTLIPSICFLIVGLILFFLYPLSKDKVLENC
                     ELLKQKHK"
     gene            complement(9782..10429)
                     /locus_tag="PB779_002115"
     CDS             complement(9782..10429)
                     /locus_tag="PB779_002115"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HDE0739631.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSIENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10513..11940)
                     /gene="uxaC"
                     /locus_tag="PB779_002116"
     CDS             complement(10513..11940)
                     /gene="uxaC"
                     /locus_tag="PB779_002116"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HDE0739632.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLWYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQTAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(12014..13093)
                     /gene="uxuA"
                     /locus_tag="PB779_002117"
     CDS             complement(12014..13093)
                     /gene="uxuA"
                     /locus_tag="PB779_002117"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HDE0739633.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLPTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIREVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13096..14727)
                     /locus_tag="PB779_002118"
     CDS             complement(13096..14727)
                     /locus_tag="PB779_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HDE0739634.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSKIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            15031..15702
                     /locus_tag="PB779_002119"
     CDS             15031..15702
                     /locus_tag="PB779_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739635.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQQGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKMNNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKNI"
BASE COUNT         5135 a         3085 c         2139 g         5496 t
ORIGIN      
        1 gagtgtaaca taaatggctt ttttatttgt ctcgcttaat tatacaaacg gcgaagatat
       61 caatgatgat ggctcaagaa aaaaagtgga gaaagttggc ggagacaccc gaccagaggc
      121 cgaagctgct ttacgaaaag ttttatcaga tattgacgaa acaggacaat actttttagg
      181 tacggatact cgagtaaaac aataccttga tttttggatg gaggaatacg ttaaactaaa
      241 tctaaaatac aatacctatg aaaactaccg atttaccatc aaaaatcata taaacggtta
      301 tttaggaaag aaaaaactta cggatctctc ccctgctctt ttacaaaatt tcatcaatgc
      361 tgaatttaaa aagggttact cgaagaaaac aatgactatt actcactctg tccttaagaa
      421 tgcgctgaat atggcggttt atccttgggg attaatcaag caaaatccta tgctgtatgt
      481 aaaaatacca aaatatgaag cacgaccaac gactaaaaaa gatctaaaaa tcatttctct
      541 tgaggacttt gatcatatgc tagaaattac tcctgaagga catcctttct atattccttt
      601 gaatattgga ttttatacgg gaatgcgcgt tggcgaagtt tgtggtctga cgtgggatga
      661 tgtcgatttt tcaaatggaa caattactgt agagaaacaa atggtaaaga atgacggcgc
      721 atgggtatat ggtacgccaa agacaagcag ttccaatcga acgattttta ttggacaaac
      781 cttgctagca attctgaaaa aacataagaa acaacaatta gaaaatcgaa tgaagtatgg
      841 aaagctctac attgattcaa atgcagtatg tacgaaggaa gacggtgagc tagttacgcc
      901 aagtgtagtg aaatggaata ctaggaggat atcgaatgca ctctccctct cttttaactt
      961 ccattctctc agacatactc atgctacact tcttctcgaa aatggcgcaa aaatgaaaga
     1021 aatctctgaa cgattgggcc acagcagaat ttcaattacg atggatactt actcgcatgt
     1081 aacagataag atgagaaatg aaacggtcga tatcatggaa aatcttagaa agaattcttg
     1141 atttttgcca ccgaaaaaaa ccaccggtgg caaaccggtg gcaaatccat gtaaacatgg
     1201 tttatttttt acactgtttt caaacaaacc cttgctattt cttcggttcg tcctcgtcca
     1261 ttttcgatac cgacagctag cttataaccc aaggtatatc aacataaaaa aataaaaata
     1321 ggctatgaca gcagcgtgac agcaaaaaag atggaaagtt aaatatcaaa cctcgtaatt
     1381 tcatttgcga gtgcttgatt tgtttctgga tataagtgtc catatttgtc caaagtagtt
     1441 ttaatagagg catgacctag acgcttagat attgcataga tatttttatt atgttcaatt
     1501 aaaaaggcaa catgcgagtg tcttaatcca tgcatatgaa ttggttttac tcctgcaatt
     1561 tcagctagtt tttttattct gcttaaaata gttcttggag atggcggtaa tccatcaaaa
     1621 gaaaaaacca attctatatt tttcccaatt gattgttgag tttttttcca tgtttttaaa
     1681 tcttcaacgg tttgtctgtc taacgaaatt atccgaatac ttgatgtatt ttttgtttca
     1741 gcaaattcat aatcttgtct tgtacggatg taaattgact tatttacgct acatctgcca
     1801 tttattaagt caaagtcttt ccattgtaac gctaagagct cctcactcct tacacctgta
     1861 acaaaaataa aacgcatcaa acgtttataa aattcttcat aaaaatcccc gtgataaaca
     1921 ctattatata ctttcttaaa ttcatcaact gtccaaaatt ctacttgagg acgctgagtt
     1981 tttattttac ctatagtatc tacaggattt tcttcaataa tttcaagtac aattgccctt
     2041 ttaaaaacta ctctcaactt attgaatatc tgtttaatat aatttggtga taatggttgc
     2101 tcaatgccct tttttacaac atggattttc gataaaaact gttgaaattc ctgtatatga
     2161 attggtcgaa tctttacaac ctgcatttct ccaaaaaaat ccaatgcacg ttgtaaaata
     2221 tgatctgttt tcatatatgt tttttctaca gttcccaact tataccaagg aaaaaaatac
     2281 tctcgataaa aatcatgaaa cgttattcct tgcagataaa ttccttgtga atcagaaaaa
     2341 ctttgtttta actcttcgag tccccttcta gcttctcctt gagttttgaa gcctcttctg
     2401 gtcacttgaa ttctttttcc aaagcgatct tgtcctaaag ttgcagaaaa aaaccaagtg
     2461 cctctttttc tgtctttata aacattcgca attttcctca ttttactatt cctcccaaga
     2521 aatatggaga acttcttcta aaattgaaat aggaattctt tttatttttg aattacgata
     2581 aaaaaagtat cctttctcaa ctaaaagttc tttacattcc ttgaagattt tattagcata
     2641 gtactgagaa aaacctagat taatcaaatc ttttcgagta gctgttttca ttatagcacc
     2701 ttccttactt tttttcattt atttctatca gctgcttttg tcaaaagcac ataggaattt
     2761 cacctctccc caagtttacg gcgagcctta cggaagtatc attatcccaa ctttaaatca
     2821 tcgcttttta ttgactataa aaattatttt agaatattta tcgctccttc tttacagcaa
     2881 gaaatcatgg cgcaactaaa atatgctcct taaagtgtta acgtactgat agaatctatt
     2941 taattttcaa tgaacaatag gttttctacc taaaagaatc tactaattcc ttaactatta
     3001 gaagattctt ttaaacagaa aaagtggaaa ggggattttt ttaattagtt aattttaaat
     3061 tttaagatcg cttctattaa tttaatttct agctgactta tcatatattc atctacatag
     3121 gtaacgaatt gacctacctc gttaaatcca tttgtcaaac ataacttagc catataagaa
     3181 tgataatgtt tgagtatcat cttgatcgaa attggatctc cttctagagc agataagata
     3241 atggatagtg gaactaatag gtactgccgc tttttagatt tatctaccat aggtcatacc
     3301 ccattttcaa ttgttcaact gccttctttc gttgatacca gataccactt gtgctcatat
     3361 tgagaatttt accgatttca gcatcattaa aacctgcaaa ataataaagt aggataatct
     3421 ttcttcttat ctccgataac tgatcaattg ctgctgataa cttttgatct gaaattaata
     3481 tttccattcc aaataagaaa tagacatctt gttcatcaaa atgagtttgg gaatacctgc
     3541 cttcatttga atctgccaat ggttcctcat tatcctttat gttagcgttt cgttttcgaa
     3601 tagacttagc ttcgtttcgt aatacttttt tacagtaggc atcaaattgg tgttgtatag
     3661 atatgtcatt gtaatgttgt tgcatgataa tatgctcctt tttccccctt tccactaata
     3721 caacaatcag aaagcccctt tttttcgaaa aaactagaaa aaaaacataa aaatatttat
     3781 cattctttaa acagaaaatc tttctataaa aaacaaaaaa aaacgattag gctaggctaa
     3841 tcgttttttg aacattctta aaaaatccaa attatttttt ataactgaaa ttgggtattg
     3901 atgaccatcg tttctgtaga tagtaagcaa tcattttagg ttttctatct ctagtaaaga
     3961 ttcctttctt atttccttgc actcttaaaa tcccttgact tgttgcaaaa tctgcaaaat
     4021 tccacacttg ttcaccaaca aaattttcac atgtatctat tacttcgtga tttgcttcgt
     4081 aataagccac ttgatactct tctgtaaaca ttgttggtac tgtatcatga aatccagcta
     4141 ctgtatctgc tccatattct gtaaacatta ttggcgtatc aggacatctt tccatccatc
     4201 catctagctc ttttttcaac agatattttg catgtgccag atcccctccc gaaacatacc
     4261 aaccataata acgatttaaa cataaaacat cgacaatatc tcctacctta caaacatctg
     4321 gcgttgattt tagataagta acgattgtta caggtctttt ctgcggatca agttctttag
     4381 ttaattcaac taaaggttca aaatattctt tagcaccttc ggaatccgaa tctggttcat
     4441 ttgcaataga ccacattaca acacttgggt ggttcttgtc gcgttctatc aattccttga
     4501 tcaccgtttt atgagaattt tctgttcgta tctctttcca cgtattatgt ttttccacat
     4561 tatcatctaa taaagtggcc atgaaattta aatgtaaccc tactgcaggt acttcatcaa
     4621 taactacaat accttctcga tctgctaatc gcataatttc ttctgagtaa ggataatgtg
     4681 atgttctaaa agaattagca cctatccatt tcattaaatt aaaatcttta atatttacag
     4741 cctcattcaa accacgtcca ttaacatacg aatcctcatg cttaccaaat cctttaaaat
     4801 aaaaaggttt attattaatc aaaaatttgc cattggtaac ctgaacactg cgaataccaa
     4861 attcttctgt ataggtatcg atcactttat tatcatcaat taaactaatt ttcatactat
     4921 ataaataagc gtctagaggt tcccaaaaaa ttggattctt aagctgaatc attcctttct
     4981 ttccttcagc ttcagctaca agttgagcct cttcgtcata tatcgctatt aagatttttc
     5041 cggtccattc tgtatcgata ttgaattcta cacttgcatc caaatcagtt attcttgtat
     5101 taatagtaat atcacttata tagtctttcg gagttgtata taacttaaca ggtctatgaa
     5161 tacctgcata attgaagaaa tcaaaattaa ctaagttttc cttttttata tccccatttt
     5221 cctgtactgt ttccttcata atccccacag gtaaagtact atcgtcaata atattgttta
     5281 cagcaactgt aattcgatta ttcccgtctt ttacaaaccg attaatttca gactcaaatg
     5341 gtgtaaaccc acctttgtgt tgagtaataa actttccatt caaaaaaact tttgcttcat
     5401 gtgttgcaga tccaaaacga agaactaatc tttcttctaa taatctttta ggaagagtca
     5461 cttctttttc ataccacacc catccaacat gatttctaat gttctctgtt tcaaataaat
     5521 cattataaga agagggaact gaaatcggat aactctcttt ttcatttatt ggttctaaag
     5581 caagttcttc ctgtaagtca tcatttgtat ctaatttaaa tctccagaga ccgcttaagt
     5641 caattacttg cctcgtctct gtcataatgg gatacaacat ataaaccact cctatctaaa
     5701 tattaaataa atgtatcctt taaaccacaa taagcatcta ttggacttac tcccttaaat
     5761 tcagaaagac ccattagttt gtccaccaat atttctaaag tttcttgttt tccatcataa
     5821 gtattaatat aagtctttac ttgaggtaca tcagccaaat gaaacggaca ctgtacagat
     5881 acaaaaattg ttggaatttc atgaatgtaa aacggtatat ccggagttcc tttacttgct
     5941 ggccagacaa ttcgttgaac tgtgcctgga ttaacattag ctatattaat gatcaagtca
     6001 tattttttag ttaaattttt aattggtctc ttagcagcat atattccagc tatattttta
     6061 attttttctt cttgcgataa tcctttcaat tcttcttcag gtgaaatgta tttttcaact
     6121 tcaaatcctt ttgctgacaa aatctgtttc aataaatcaa tggcttgagg tctatttcca
     6181 gcaactactt caccaaaccc accttttacc ccatgtacat ctactagtaa aatcctttta
     6241 tatttttctg gtacaatagg ccaaatatct tgtttatctt taactaatgt aattgcttgg
     6301 tcagccacct ctttaaaaat tgatttattt tcaattaaac caattttttc cagagcttct
     6361 tgcttaggta ataaaatttg ttcttttgct tttttgtgta atcccaattt agcttttaac
     6421 cctaaaattc tttttaaggc atctaataac cgatcatcag tgataattcc tttacgatag
     6481 ccttccatca tataattaaa gtcttcatct ggatcattaa aaaatagaaa tagatcacat
     6541 ccagctgcaa tagaagtggg caataattct gatcgtttca ttgccccagt cattcctaac
     6601 atatgactag catcagtaac tactaatcca ttaaatccga gttttcctct aagtaagtca
     6661 gtgattaatt cttttgataa agttgcagga agtaaatctt catctttcag atcaggatta
     6721 aaatgttttg aataagctgg catatggata tgacctgcca taattgaagg taatccagct
     6781 tctattaagc ctgagtatac ttttccaaaa gaattatccc attcttccgt acctaaacta
     6841 ttaatactaa aagatagatg ctgatctcgt tcgtcaatac cgtcaccagg gaaatgttta
     6901 gctgcaggca aaattccact ctcctgaata cctttcatat aagctaaact aagttctaaa
     6961 actttatcag ggttttgtcc aaaagatcga ctagaaatga taggatttct ccaatttcta
     7021 ttaatatcta caataggagc aaaactccag ttacatccaa tagccgatgc ttcaatccca
     7081 gaaactctcc ctaattcata agcatatttc gcatcatttg ttgcaccaat ttttacttct
     7141 acaccaactt cagtaccatc tgtacaagct ccgttaccac ctgcttccgt attagcagca
     7201 attaatagag gaattttact ttctgtttgt aagatatagt tttgatcata tacctcatca
     7261 gcagttcctg gattatatcg tacagctcca atatggtact gattgaccat attactcaag
     7321 taatttttat cacgactaga tcccatatta acaaacaatt gacctatttt ttcttccaaa
     7381 gtcatagaat caatcgtctc ttcaatccaa gaaatagcat cttcatctaa attatatggt
     7441 ttttttcgta aatctacttt tatagtcatt ttctttctcc tctacttatt agtaagattt
     7501 ttccaaaaag tatctatata tttttgttca atatctacat aatctcccga taaacattta
     7561 aataaaacat cagttcttaa gttttcccat gattcttttt ctttattgac caaaatagga
     7621 taaaagaaaa ctttattttt atttgcagct tctagatcac caggagaatc accaatcatt
     7681 aatatcttat ccaaatcaca accattttca attacacttc gaataatatc ttcttttttt
     7741 cctttatctt gacaacacag ttcatcaact aatgataata attcatgtct ttcccattct
     7801 tcttgaacag cttccttatt agctgagctt acaataatta tcttcccata ttttttcaga
     7861 gcttttatag tatctctagc acttaaaaag ggtttatcta atccttttgc ttgactaatc
     7921 tgttgattga cttcttccga ccattttaaa gcttttaata aatcctctga ctgagaatat
     7981 tctatttccc tcttcaaaga tggattagac aattcttttg ttagagatac ccagtgcttt
     8041 aatcgattaa tcgatgttac atcatttttt tctaatgttt taactaaacc taaaaatctg
     8101 tttattccac gagtctctga atataaatta atattattcc aatcctgtag gaatttttct
     8161 ctatgatgaa catcaaaaat ctctgcagca attggtccga aaaagagatt gtgtttataa
     8221 gtcatcgtat ccataacaca gccatctgaa tcaatacaaa atatccaatt attcatattt
     8281 ctctcctatt tatgtttttg ttttaaaagc tcgcaatttt ctaagacttt atctttagat
     8341 aatggataaa ggaaaaataa aattaatcct acaatcagaa aacaaattga tggaattaat
     8401 gttgaagcgt tatataactt ttctaaaaca tctcccgttt gtacatttgc taaagagtca
     8461 tagcctataa tagaaagagt ccaacctccg acgcctccag ctagagcttg acctattttt
     8521 ctagcaaaag aatataccgc atatacggtc ccatcttctc tttgatcaga ctttacttct
     8581 tgatcatcaa taacatcagt aatatttgcc caaataacag tattaaacac acccaaaccc
     8641 atatagccaa ccgaactaag aattaagaat acatacatat tactagcttt tatcaaaaat
     8701 aagatcaaat atactattgc tgaaaagaac attcctactg atgccagttc tttttttcca
     8761 tattttttac ttaaaaacaa agttaaaggc gaaacaacta ttaaaaccaa aataggattg
     8821 ataaaattca ttaaaactat tccctgtgca tcattatagt aatcaggaaa tacataatta
     8881 ttcatactca taattaataa ttgagcaagg agtaagaaaa tagccgcacc aattatagaa
     8941 agtaatgccc tatttttaac taaccctttt aaagatttta acaatgaaac tttgtattga
     9001 gattggtcaa ttcttactcg ttcagtagtt agtttataac atattaaata acaaataagt
     9061 gcacatatcg aaaatattcc cgcaacaatt gtaaaagttg atccaccacg aactatttga
     9121 gcgcctgaat catctcttgt ataaataaat aatggtgtta atacaccaat gaccaaactt
     9181 gctaaagtag ctccaacatt tcggaatgtc gatagcattg ttctttcttc tgtaatagaa
     9241 gtaatagctg atgccattga tccataagga atatttatag atgtgtaaaa aatactcccc
     9301 cataatatat acgtaacata catgtatact accttaacgc tcatagaagc tgaaatcata
     9361 gaagtttgat acattaaaaa acttgctaaa gcgactggac cactcattct taaaatccac
     9421 ggtttaaact taccctgctt agttgctttc gatctatcaa caatacgccc catagttaca
     9481 tcagtaactg catcgataaa tcttgctact aaaaataatg ttccaacggc agctccgctt
     9541 atccccaata cttttgtata aaagatcatt aaaaaagaac tagcaaaaat gaaagtaaaa
     9601 tcgtttccaa aatctccaaa catatatcct attttgtctc ttataccaaa ttttctttcc
     9661 atacaattct ctcccttctg ttgttaagcg ttttcattct gatgaaagta cgtactatac
     9721 tctgaagcgt aaagagtcag tatttatttt ttacatttca gagtattatt tgttttttct
     9781 cctaataatt ctttatctca taaaacttat ctatatattt actagctact cgacttactt
     9841 cttcaaaatc acctttttca acagaagcca ataaattccc acctacacca actgcaacaa
     9901 ctcctacttc aaaccaatct tctaagttct ctatacttac tccgccagta ggcattatat
     9961 ttacgtgtgg taatggagct tgataggctt ttacaatgga tggaccaaaa gcagaacctg
    10021 ggaatagttt aatgatatct acgccagcag taagtgcctc ctttatctca gtaattgtca
    10081 tacaacctgg taaataagga atttgatata aattacaaat ctcagctgtt tgtcgatcaa
    10141 aagatggact aacgatatat tctgccccag ccataattgc gatacgagca gtaaacgcat
    10201 ctaaaaccgt accggctccg attattacat ctttttgatc agcatatttt ttagcaattt
    10261 ctttgattat ttcttcagca ttaggaactg taaaagttag ttcaatccct ttaattccac
    10321 ccgcaataat tgaatttatt gctttaatgg cctcatcctt atttttccca cgtacaaccg
    10381 caatgactcc agccgcttct aacttactta aaatttctac ttttttcata tctatctcct
    10441 tcctttatgg atacatactt tgtctagctg tactaactta caaagaataa atttaagctt
    10501 ttatttcaag tattattttc tacttccgat ttcaaaaaaa ttaaaataat tatacgcatt
    10561 acgataacaa atattctcca ctatctgact aagatacatt tcatcatctg gaattcggcc
    10621 tgctttaacc cactcgctta gtaattgaca taatactcga cgaaaatact catggcgagg
    10681 atagcttaga aaacttcgag aatcagtcaa catacctgta aaattcgaca acaaactttg
    10741 ttgtgccatc gtagtcaact gttgacgcat tccttcagct gtatcattga accaccaagc
    10801 acatcccaat tggatttttt gaatcatacc cccttggaag ctttgcattg ctgttgctag
    10861 tggaagccaa tcagttggat ttaatgaata taaaattgtt tttggtaagc acccactctt
    10921 ttcagcggta tcgaacaatg ctacaacatt ttgtgtcaaa ctagcttgat cccccatcga
    10981 atcaccaccg acatctactc caatttgttc ctttaatata cttgaattat ttcttaaagc
    11041 atttaaatgc atttgcatcg tccaaccata tcttgtatac tcagacatca aatgtaattg
    11101 aatacctgta acaaattgtg caatttctga taaatggaaa tccgtttttc ctgctaaagc
    11161 ttttattaac agattgtcga gtattttttc atctgctatt tcataaaaat aagtattcaa
    11221 accgtgatct gctaatcgac agccaatttg atgaaaatga tccactcgtt ggctcaatgc
    11281 ttgcttcaac ccattaaagt ctttgattgg tatagccgct gtttgactaa gttttaaaat
    11341 atagttcgaa aagcctgatg atttgatact ccagacctta tctggacgga aagtaggtaa
    11401 taccttgaaa gaattatcct gtttagaaag ctcagtatga taccacaagt catctgtagg
    11461 atcatccgtt gtacagatgg ctttcacatc catcatctcc aacaattctt tcgggcgata
    11521 ggaatccgtt tgaatttttt cgttagcacg tcgccaaatt tctggtgcat tcttctcaga
    11581 aattgtcaaa tcaatatcaa agtaacgttg taattccaaa tgagaccatt caaaaatagg
    11641 attacctggc gccttctcca ctgtttttac aaaagctaaa aatttttcat aatcatcacc
    11701 tggaccactg atcaactctt cttctatacc attagctcgc atcaatcgcc atttataatg
    11761 atctccagct cctttatcat ttaaccatac ctgagtcaaa ttcttgtatt gcttattttc
    11821 tagcaaatat gctgggtcta aatgacaatg atagtcgata attggttggt gttttgcaaa
    11881 tttatgaaaa agtcttttag ctatttcatt ctctaataaa aagttcttat ctaaaaacat
    11941 atttaaacac tcctttcctt ccgttagttt ttagaagaga aaatttttcc tctaaataaa
    12001 ctcccttata taattattta ctcgccccct tttcaagcgc ttcccaaata ccatttaaat
    12061 aaactgcacc tagagctcgg tcatataatc cataaccagg tctaccggtt tctccccaaa
    12121 tcatccgacc atgatctgga cgaatatagc cattaaatcc attatcgtac attgttttta
    12181 atatcttata catatctaga gaaccatatt ctgatttatg cggcgcttcg taaaaatcga
    12241 gtccattgtc acttaaatat ttgatattac gaacatgtgc aaaaggaatc cgatcccgtt
    12301 gacaaaattc agatagaatt tcatagacat cattatctgg tcgttctgca atacttccag
    12361 tacataatgt aataccatta gaaggagaat ccactacatt acacaaccaa tctaaatcgt
    12421 cacgattttt aacaatacga ggtaatccga aaatggaata tggtggatca tctgggtgaa
    12481 ctgccatttt aatcccaact tcttcacatg tcgggataat tgctttgaga aaatatgcaa
    12541 agttctctcg taatttctct tcatcaactt ctttataggc ttctaataat tgcttaattt
    12601 gtgataaccg atgaggttcc caacccggca attcaaaatt attagtagaa ttttctactt
    12661 ctctaataat ttcctccgga tcagtaggga tattttttga aatataggct aacgtagaag
    12721 acccatcatc taaacgataa tccaaatccg attttaccca atcaaatact ggcataaaat
    12781 tataacagat aacctcaatc ccaaattctg ccaaattgcg aatcgtctgt ttataattct
    12841 caatgtattg atctcgtgtt ggtaaaccaa ttttgatatc atcatgaaca ttaacactct
    12901 caataacttt caaggtaagt ccattggctt cgacttcatc ttttaaagat ttaattcgtt
    12961 ctctcggcca aacctctccg gctggtatat ccattaatgt tccaacaatt cctttcattg
    13021 ctgggatctg acgaatttct tgtagtgaga ttttttcttc atttgcccca taccatctaa
    13081 aagtcatttc catagttact ttcctccaac ttctgttata tatttattga ttgttttacg
    13141 aactgcttga ggacctacta gcatttcgca aaagattttt tcagttttct ttcctacccc
    13201 aacttgatat aaatctaaac caaagatttc tttattttct aaaatttcct gtaccgcaca
    13261 atgaatcttt gaaggatctt gttcacctaa tttcaatact gataatttat cctgcaactc
    13321 taccaataac ggatcaggac ttggcacaaa attttcccct tgatcatcga ctgccagtaa
    13381 ataacgtaac caagcagcaa tagcgatagg aataaatgtt agattttctg catttccgtc
    13441 tttttcgaca tactttttaa ttgtttcacc atagcgaatc gctacttttt gagaagtatc
    13501 tgttgcaatt cgttgtggtg tatctggaat atagggatta ggcaaacgtt tattaattac
    13561 ttcatcaata aattgttttg gatcaataat gcctggattt tcaactactg gtaaaccttc
    13621 taaataacct attcctttga ttaaaccaac caaatcatca tcctgcatct ctgctgaaat
    13681 tgattgatat cctagcagac aacctgttac tgccaaagca gtatgaagtg gattcaagct
    13741 tgtcgtaacc ttcatgatgt ctgctttatc aaccgtctct ctatctgtca taatcacacc
    13801 agccttttcc aatttaggcc ggccatttgg aaaactatct tcaataacta aataatgaac
    13861 tacctcagta ttagtgaaag cagcaatatt ggtatgtttt tttgtgtgaa tgatatctaa
    13921 atcctcgagc cccatcatca atagatcttc ctttacattc tctgaaggat ttggcgtaat
    13981 tcgatcaatc atactccaag gaaaagtcac tttttcttta tcctttaaat aagcaataaa
    14041 tttttcagaa acatatcctt ctttttgcca agcttctgca atcgtaaaaa tactatcttg
    14101 aaaacgttga ccattctgtg agaaattatc agtagaaacc atcgcaatcg gcaactctcc
    14161 agcattaaat ctgctatata acaaggatgt tacaatactc atcgtatgtt gaggattgct
    14221 aggtccagat ttgatatcag ctttgactac cgaaaagaat tgccctttag aatcttttaa
    14281 actgtaacct ttttcagtaa tagtaaacgt tgtaaactgt aatttaggat cttcaaaata
    14341 tttaaccact ctttgatagt ccgctatatt cttcggattg caatataaac tatcagccgt
    14401 tactgccaaa agtctttttt tgagttcacc atctccactc ataacaattt ccaaaatgtc
    14461 attgttatag tcatgataag ctttttccac tacttcttca tcaaatgttt cacacacaac
    14521 tactcctgtt tctaattcat tttgatctgc taagcattga gcaatttctg catgaaatcc
    14581 tcgataaaga tttcctccac caaaatgaag ccatactgga tgttgctggc cttcttgctt
    14641 aacttctttg acatcaaaac acggcagtag aatctgcatt tcattgaatt cttcgataga
    14701 attttgccaa tttttaatcg aaaccataat taacctcctc aaactgatat gttagttttg
    14761 atacatttta tattttaaaa cccattgtaa ccgttgtcaa tataaaaagg gaataaactt
    14821 gcttttttct accatatcag aatgattgta ttttttattc agaaaaataa aatactcctt
    14881 ctttttggac tgattttatc gaaacttatt ttttcttttt ttcatgtatt cttttatttt
    14941 tataactagt gtattacttc aaaatttgat attatatggc atgaacagaa ttaaaatatc
    15001 agttaaaata aaagttaagg agcattgtgt atgacaatta aaactagtct ccaaaatcaa
    15061 gcttaccaat ctattcgccg acaaattatc tatgctgact tagaacctgg aaaaaaagta
    15121 tcagaaaaaa aattagaaga aacactttct attggtcgta caccaatacg tgaagcactg
    15181 attcaactcc gacaacaagg tcttgttgat acaattcctc aaagcggaaa ttatatctca
    15241 ttaattgatt tagattcggc caaaaatgct cgatttgtca gagaacattt ggaacgacaa
    15301 attatgttag agtgttgtgc caaaatgaat aaccaaaaaa aacggatttt agaaactata
    15361 atttcagaac aagaaaaagc tgttagtcaa aaaaatgctc gtagtttttt tcataatgat
    15421 aatttattcc ataaagcttg ttttgaaatt gcagagcgag aagaagtatg gcaatggtta
    15481 gaaaataaca atacacactt agaacgattt cgatggctac gagtaaaaac ggaaggatta
    15541 aagtgggaaa aaattatgga acaacattat caactatttg aggcattaac aaaacaagat
    15601 ccagaagaag ctaactttct aacatcgttg catcttcatt taatgcttaa tgagcaaaat
    15661 attgttttag ctactcatcc aaaatatttc aaaaatatat aacttttaac tctttttaaa
    15721 ttaaatggtt gttctgatca gaaaaatatc gcttgttttc ttattatgta atatatttca
    15781 taaactattc tgcataacaa ctattgtttg tactttttac attggataac taattatgac
    15841 tgctgataac ttttg
//
LOCUS       DAMEEU010000064        15317 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.065, whole genome shotgun sequence.
ACCESSION   DAMEEU010000064 DAMEEU010000000
VERSION     DAMEEU010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.065"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(98..556)
                     /locus_tag="PB779_002120"
     CDS             complement(98..556)
                     /locus_tag="PB779_002120"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HDE0739636.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            complement(727..1872)
                     /locus_tag="PB779_002121"
     CDS             complement(727..1872)
                     /locus_tag="PB779_002121"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HDE0739637.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            complement(1885..2802)
                     /locus_tag="PB779_002122"
     CDS             complement(1885..2802)
                     /locus_tag="PB779_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HDE0739638.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIYL"
     gene            3230..3793
                     /gene="efp"
                     /locus_tag="PB779_002123"
     CDS             3230..3793
                     /gene="efp"
                     /locus_tag="PB779_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HDE0739639.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            3894..4064
                     /locus_tag="PB779_002124"
     CDS             3894..4064
                     /locus_tag="PB779_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739640.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            4279..5538
                     /gene="lysA"
                     /locus_tag="PB779_002125"
     CDS             4279..5538
                     /gene="lysA"
                     /locus_tag="PB779_002125"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HDE0739641.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            5525..6325
                     /gene="dapF"
                     /locus_tag="PB779_002126"
     CDS             5525..6325
                     /gene="dapF"
                     /locus_tag="PB779_002126"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HDE0739642.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            6328..7209
                     /locus_tag="PB779_002127"
     CDS             6328..7209
                     /locus_tag="PB779_002127"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HDE0739643.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            7206..7922
                     /locus_tag="PB779_002128"
     CDS             7206..7922
                     /locus_tag="PB779_002128"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HDE0739644.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            7928..8623
                     /gene="dapD"
                     /locus_tag="PB779_002129"
     CDS             7928..8623
                     /gene="dapD"
                     /locus_tag="PB779_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HDE0739645.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            8639..9640
                     /locus_tag="PB779_002130"
     CDS             8639..9640
                     /locus_tag="PB779_002130"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HDE0739646.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEEPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            9637..10998
                     /locus_tag="PB779_002131"
     CDS             9637..10998
                     /locus_tag="PB779_002131"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HDE0739647.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            10958..12109
                     /locus_tag="PB779_002132"
     CDS             10958..12109
                     /locus_tag="PB779_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HDE0739648.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            12084..13253
                     /locus_tag="PB779_002133"
     CDS             12084..13253
                     /locus_tag="PB779_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDE0739649.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            13428..14807
                     /locus_tag="PB779_002134"
     CDS             13428..14807
                     /locus_tag="PB779_002134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDE0739650.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            15088..15317
                     /locus_tag="PB779_002135"
                     /pseudo
     CDS             15088..15317
                     /locus_tag="PB779_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5018 a         2717 c         3280 g         4302 t
ORIGIN      
        1 gttttcccgt ttagaactct tttcagacaa taaatattta ataaaatacg aagataagat
       61 agctatattg cttctcatct ttacgttctt ttagaaacta tgcttctact tcagaccatt
      121 catcgcgttt tgctaaaaat tcacgagcca aagcttgtgc accttctagt gtatggctgg
      181 cagcccagcc acattgtgtt tcattgcttg caggtacttc agtagcttca agaacatctt
      241 tcattgttgc ttcaagaaca tctaaaatgt cttcgtagct ttcatgattc aatacagtca
      301 agtaaaagcc tgtttggcat cccattggag accagtctac gatgtaatct gcgtgattgc
      361 ggattagttc ggcagtcaag tgctcaagtg aatgtagact tggcatgtcc atgtgttctt
      421 tatttggttg tttaaagcgg acgtcgtatt taatgatgac atcgccatgc gcacccgttt
      481 ttcgatcagc tacacgtaca taaggtgctt tgacttttgt atggtcaaga ttaaaacttt
      541 cgacattcat tctcatttgt aagactccta tctgtttgtt cattcgtttt gatgcttttc
      601 actaaagaat tatttagtga aatttacaaa aacgtctttc tacttgattc taacacttat
      661 cgtttccaag gtgtagcaat ctgaaatatt ttttagattt ttctgctaag tcgtttattg
      721 ggacttctag ttcttgattc tgtcaaatgc ctgagctaaa tcgtttatga gatcctgacc
      781 atactcaatt cctacagaaa gacggatcaa gccgtccttt atgccagcct cttctcgttt
      841 ttcttttgga atagacgcat gagtcatgac agaaggaatt tccactaaac tttctacgcc
      901 acctaaactt tctgctaaag taaatagttg gagtgattca acaaatggaa tagcagattc
      961 ttcatttttt aaagtaaaag aaatcattcc gctaaagccg ctcatctgct gcttagcaac
     1021 tccatggagt tcatgatcgg gtaatcctgg atagtagacc ttttctactg ctggatgaga
     1081 aaatagaaaa tcagctacca caaaagcatt tttttgatgt tcctccatac gaacacttag
     1141 tgtcttgatt ccgcgctgaa gtaaccagct atcttgggga ccaagtacgg ctccgatagc
     1201 attttggtaa aatccgatct gatcggctag atctttatgg ttagaagtca ctaaaccagc
     1261 tactacatcg ctgtgtccgc ctagatattt ggtaccgcta tggacaacga tatcagaacc
     1321 gagatctaaa ggtctttgaa aataaggagt agcaaatgta ttgtcagcaa taactatcaa
     1381 tccatgttga tgagccagag tggcactttt ttctaaatca gtaatcttta gaagcggatt
     1441 gctaggtgtt tcaagataaa gtgcttttgt attgggtttg atggattgtt ctattttatc
     1501 aagattactc gtatctatga tcgtgtactc gagaccattt ttagtaagaa ctttgtcaaa
     1561 tagacggaat gttcctccat agacatcatc tcctaataag atatgatcgc cagcttgaaa
     1621 aagagaaaaa acggcatgaa tcccagaaag accagaagaa aaagcgaatc ctcgaacacc
     1681 gccttccaaa tcagcaatca gttcttccaa tgcaaaacga gtaggattac cagatcttga
     1741 atattcatat tgtttaggct ggccgacgcc atcttgccga taagtggatg tttgataaat
     1801 aggtacactg acagctcctg ttgtgggatc ttcactgatg cctccgtgga tcaattttgt
     1861 ttgaatgtgc atgtttcttt cctcctataa gtaaatgttt tttgataaat agcggtctgc
     1921 tgcgtctgga aaaatcgtaa cgacacgatg accaggtggt aaacgacgaa tttctcttaa
     1981 tgctgctgca aaagccgcac cactcgaact tccaactaat agtccttgtt ctcgtgctaa
     2041 ctgcctagta tagttaaacc cttctacatc agagattgtc tcgatctgat tgattgaaag
     2101 gggagaaaga aacggcggaa tgaattctac accgataccc tcaatttcgt gaggggctgg
     2161 atcaccacca tttaacacag agccctctgg ttctacaccg attattcgaa tgtcgggata
     2221 tttttctttc aaaaaggtag aagttccagc aaaggttcca ccactcccaa ttcctgctac
     2281 aaaactatgg atattttctt tgatttcatg aaagatttct ggccctaacg tatgatagta
     2341 agcagcagga ttatctttat tttcaaattg aagaggcaga tagctgtttg atatctcctc
     2401 tgcaagtttt ttacttttgc tgatggcacc gatgattcct tgctcactag gagaatggat
     2461 gatctttgct cccaatgctt tcatcaattg ttgtttttct aagctaaact tctctggaac
     2521 aacaaaaacc gttcttaatt tgtatgtgag tgcggccaga gcgatcccaa ttcctgtatt
     2581 tccggcagtt ggttcgatga tcgtcgtttt ttcattgatt tttccttggg caaatccttc
     2641 tttgatcaaa taactgccca atctatcttt gatacttcct ccaggattta aatattctag
     2701 ttttgcataa atagcagaac ctttaggcat agaatagtgc tgattgtcaa agcgataaag
     2761 cggtgtggaa ccaatagctt ctgtaattgt cgagataatc atgtgggcct cctaaaaaaa
     2821 gataataaaa aaaggagctg actattaaat cagctccttg aaagacatag agaaaaattg
     2881 agtagataaa aagataagtt acctggtact cattctatga agggcaatta atagacatga
     2941 caaatagtat gctgctttta tgcaccatac aacagcaacg attcaattgt ttttggttgc
     3001 tgactgtcat gtgtatccct ccaagtaaaa tttttattaa cgatagcatg aaaaaaaata
     3061 aaagtcaaag gcttgaaaga aaaaaatatt tcgatagcat cgtttacccg tgtttatttt
     3121 tctgacaaat aggcatgaga ccttaaaaga tagagaatac tctagttttc tggccggttg
     3181 tctgatacaa taaagttgat tatgataaag aaaagaagga gcaaaaataa tgatctcagc
     3241 aagtgattta agagccggta tgactttcgt acaagacggc aaactgatta aagttctgga
     3301 tgcaagccac cataaacctg gtaaaggaaa tacagttatg cgtatgaaac tgaaagatgt
     3361 ccgttcaggt gcaacatacg acacaacgtt cagaccagaa gaaaaatttg aaaaagcaca
     3421 tatcgacaca aaacctgtac aatatttgta cacgatggat gatacagctt tcttcatgga
     3481 tttggaaaca tatgagcaat atgaaattcc tgtagaaaca gtagaagaag aaatgaaata
     3541 tatcctagaa aacatggaag taaaaatcca atttttcggt agcgaagtca tcggcgttca
     3601 attaccaaca actgtcgtat tacgtgttgt ggaaacacaa ccttccatca aaggtgcaac
     3661 agtcactggt tcaggtaagc cagcgacaat ggaaactggc ttagtagtca atgttcctga
     3721 cttcatcgaa acagatgaat tgttggaaat caatacagca gaaggttctt atgtaaaacg
     3781 tgcgtcaaaa taattcgcta acggattgat aagaatttga aaacagagct tgacctcttg
     3841 aaaggcagat catcggatct gcctttcaag aggttttttg tggaatcagc aaattgaaaa
     3901 ataaaaaagt atttgatttt atttatattt tgaaagatga atggcaaaag ctagagaaag
     3961 aaaaaactgc acttatttat gaagaaattg aaatgattca taaaattgaa aatatccgaa
     4021 ctattccgaa ctatattgaa gcgaaaatat tttttcatca ctaaatagtg ttgaatttat
     4081 gtttttatgt ataaatagct tctaatagtt cgggtatttt gtttttataa ccatttttat
     4141 tcttattttt aaaaaaatat ttcgaaatat actagacaat tcagaaaatt ttgtttaata
     4201 ttattccaat aaaattcaaa tctttatcaa atgaaattcc aataaaaacg gaaaaaaagt
     4261 gaaaagagga atgaaaaaat gacagaattg ataattggcg gagtcacagc aagcacattg
     4321 gcagaaaagt ataagacacc tctgtatgtg tatgatgaag aaaagatgag acaaacgatg
     4381 ctgtcattca agcgaggctt tgtatcgaaa cgttttgata caaaagtgct ttacgcctct
     4441 aaagcattcc aaacgattga gatgctgcat ttagttcgtg aatatggatt cgggctagat
     4501 gttgtcagtg gtggggaaat ctataccgct ttgcaagctg attttcctag agatactatc
     4561 tacttccatg gtaacaacaa gacgccagag gaactgatct atgcacttga aaatgatttg
     4621 ttgcatattg ttgccgataa tttgatggaa gttgaattat tagcagaatt aagccaacgc
     4681 tatttaaaaa aaatctgtat catgcttcgg ttgaatgtcg gagtagaagc acatactcat
     4741 gaatatatcg tcactgcgca tattgattca aaattcggca tgagctatga aagtaaagag
     4801 tgccaacaag cccttcagtt gataaaagaa agcagctatc tagagttaga aggatttcat
     4861 gctcatatcg ggtcacaaat ttttgatgtt actgcttggt tagctgaaat cgacaaattg
     4921 acgaattact taaccgattt tgaccaacct ctttccttga atcttggcgg agggtttggg
     4981 attcgttata cacaaaatga tcagccgatc ccagtcgaag aggcactaaa aaaactgatt
     5041 gaatatacgg aagaagcttt ggaaaaacga aaactgacca ttcgtcaatt actgatcgaa
     5101 ccgggtagaa gtattgttgg agaagctggt acaacactat acacgattgg tttcatcaaa
     5161 aagacaccac ataaaaaata ttactttgta gatggcggga tgacagataa tatccgtcca
     5221 gctctgtatc aggcagaata cgattgtgat ttagcagcaa aactgtcgga agaaaaaaca
     5281 gagaaagtga cgattgcagg aaaaatgtgt gaatcaggcg atgtggtaat taaagaagct
     5341 tatttgccga aagcagaatc gggtgatctt ttagctgttt attccacggg agcttatgga
     5401 tactcgatga gcagcaacta caatcgagcg acacgaccag cagttgtttt tgtcaataat
     5461 ggccaatcaa gactgattgt tcgcagacaa gcattttctg atctactaag gggggaagtt
     5521 tcctatgatc cttcataaat ataatggctg cggaaatgat tttatcttat tagattacgc
     5581 agaagacaca gattatagtc aattagccgc ttctttatgc acaaaagaaa aatatgatat
     5641 agacggattg atcgccgtaa aaatcgatcc gttggaaatg atctattaca acaaagatgg
     5701 cagccgcgcg ccgatgtgcg gaaatggcat tcgctgtttt gctcgatacg taaatgatca
     5761 gaacatgatg aatgaacagg aattcaacgt agagacatta gcaggcacaa gaaaaattac
     5821 ggtgttggat ccctcacctt tttattgcag cgtagatatg ggagtgccag atgattctcc
     5881 ggaaaaaatc aaagctaatc aaacttatcc aataaaaaac caggaaatag agatcaatgg
     5941 tgaaaaagta acgatcacta gtttattttt aggaacgatt cataccgttg tttttgttga
     6001 aaatgcgcgt gaggaagtct ggagaaaaag aggtgaactg atctgtcatc atcctttgtt
     6061 caaagaaaaa accaatgtca actttgtaga agtagtcaat gaacaagaat tgatcgtccg
     6121 tacctatgaa agaggagtag gttggacact tgcttgcggt acaggttgct gtgcctctta
     6181 tgtggttgct aaggaaactg ggaaaatttc agcagatcag gtagttgttc acttggaaca
     6241 aggagacttg atgatctctg gtgaggatgc gatacaaatg gctggcccag cagttcatga
     6301 atggacaaga atattggagg aatgaagatg ataaaaggtt cgatcgtggc gctgatcacg
     6361 ccgatgaatg aagagggatc agtagattat gctggtttgg aaaaattgat ccaattccat
     6421 ttagatgaac aaacagatgg attattagtt ttaggtacaa caggagaatc ttctacgctc
     6481 acacaatctg aggaggagca gatccttcaa ctgacagtaa agaaagtggc tggccgtgtg
     6541 ccggtgattg caggagctgg aacgaataat acgaaagaaa cgattgaaaa agcgaagcat
     6601 tttgcttctt tgggggcaga cgcacttttg gtcatcaccc cttactacaa caaaacaagt
     6661 gatgcaggac tagctgctca ttttacagca attgcagaag cctcaccgat tccgcttatt
     6721 ttgtataatg ttccttctag aacaggcatg tcgattccaa tccatgtatt agtaaattta
     6781 gcagaacatc ctaatatcat tggtttgaaa gaagcctcag gagatatggc ttatgtgatg
     6841 gatgccgctc ggttgattgg agaagaattc ttcctttaca gtggaaatga tgatttgatc
     6901 ctaccagtaa tgagtgtagg aggaagcggt gtaataagtg tatgggcgaa tatccaacct
     6961 aaaatagtcc atgaattagt aaaagatacg caggacggaa gatggcagca agcaaaagaa
     7021 aagcaattaa atgcacttga actgatccat gccttgttca gtgagaccaa tcctattcct
     7081 gtcaaagcag ccatgtcatt attagactta ccttccggac ctctacgcct gcctttagtt
     7141 tctctttcaa aagagaaaaa gaaacaatta gctcagcttt tgttaaaaga aaggacggtt
     7201 gaaaaatgaa aatcggactg attggcagtg gacagatggg aaatagagtc gaagaagttg
     7261 cacaagaaag aggagatacg gtccttcttt tacggacggc acctaaagaa gcaactacgc
     7321 ttgcttttac ggaactgcca gaactgctta ttgatttttc tcatccagat aatttagaga
     7381 aaatcctttc gtatagctta tcatatcaac ttccgttagt cattggcacg acaggttata
     7441 cacaatcaca gttccaagaa ataaaagaac atgccaaaca tgtacctgtg atgtatagtg
     7501 ctaatttttc gttcggcatc atggtgatga atcaactaat caagcaagca gctgcaatgt
     7561 tgcaaggctg gcagatcgaa ctgattgaaa aacatcatag tcgtaaaaaa gatgcaccat
     7621 ctggtactgc aaatatgctg cttcaaacaa tccaagaagt gcaaaagctg cagcccgtat
     7681 acaactggca agggaaaaaa agagaagaaa accaaattgg tgtacacagt attcgtgcag
     7741 gttctttacc tggtgaacat gatgtattgt ttgctgctac tgatgaaata tttacgatca
     7801 aacatgaatc tttttctaat cgaatctttg ctgcaggcgc agtagaagca gcggactggt
     7861 tgaaagatca gtcaccaggt tattacaaat tagaagattt attaatggac aaaggggtgt
     7921 aaaaaacgtg gaagctcaag aaatcatccg ctacattcaa acggcatcta aaaagacgcc
     7981 tgtgaaagtc tatctgaatg taaccgagcc aatcgaattt aaagaaagta aagtttttgg
     8041 tgaaggaagc agcttcgttg tttttggtga ctatgagacg attgctccgg ttttagaagc
     8101 tgaatcagaa aaaatcattg aaatcgaaat cgaaactgct gcaagataca gcgcagttcc
     8161 tttgctagat attaaaaaaa ttaatgctcg tatcgaacca ggtgctatta tcagagatca
     8221 agtgtcaatc ggcaacaatg ccgtgatcat gatgggagcg attatcaata ttggtgcagt
     8281 aatcggtgaa aacacgatga ttgatatggg tgctgtctta ggtggacgag cgacagtggg
     8341 caaaaactgc catattggtg caggagctgt cttagcaggt gtgatcgaac cagcatcggc
     8401 caaaccggtt atcgtagaag acggcgtact ggtaggtgcg aatgcagtga ttgttgaagg
     8461 tgtccatatc ggaaaagatg cagtcgtggc agcaggagca gtggttttag aagatgtggc
     8521 agcagaaact gttgtcggtg gaatacctgc acgtgtatta aaaataagtg atgatcagac
     8581 aaaagaaaat acagcattga ttgctgcgtt acgcgaatta tagaggagat ggagaaaaat
     8641 gcgcgaaata gatacctgta ttgtgggggc aaccggatta gtcggccaaa cgatgctcaa
     8701 agtgttagaa gaatatgatt ttccagtagg acgattgaaa ttattagctt caaaacgttc
     8761 agccggtaaa gtttgtgtat tcaagaaaaa gaaacacact gtacaggaat tgacagaaac
     8821 ttcatttgaa ggatatgatt tagcgctatt ttctgcaggt gcttctgtat ccaaagagtt
     8881 tgcgccaatc gcacgaagtc agggactatt tgtcatagat aattcctcag catggcggga
     8941 agattcggat attccattaa tcgttccaga ggtcaatctg gaagactata cattgaatcg
     9001 gctgattgca aatccaaatt gttcaaccat tcaagcggta cttccgctta aagctttaca
     9061 agaagccttt ggtatccagc gagtcaatta ttcgacctat caagcagttt ctggttccgg
     9121 gcaaaaaggc attgaagatc ttcatcgtac gcaaaatgac gaggaaccag ttttgtatcc
     9181 ttataatatt agccaaacgg tgattccgga aatcgatcag cctttggaaa atgggtatac
     9241 aaaagaagaa cagaaaatga taaatgagac ccgtaagatt ctgcatcagc ctgctttgcc
     9301 agtatcagca acctgcgtac gtgtgccaat cgaaaatgga catggagtct ctgtggcagt
     9361 tcaactgcaa aaagagttta cgacggaaga aattagagag tgtctcagcc agtttccagg
     9421 gattcaatta gaagatgatc tagcagcaca taaatatccg acgagcattc ttgctagagg
     9481 aacagatatg gtttatgttg ggaggatcag aaaagacact tctttagaga acggattgtt
     9541 gttctatacg actgccgata acatacgcaa aggagccgct gcgaatgccg tacagattgc
     9601 tgcagcttta atgcagaaaa tagcggaggt ggcaagatga gtaatacgct gaaagtagcg
     9661 aaattcggcg gaacatcgat gtctcatgaa gagcaattca aaaaagtccg tacaattgtt
     9721 ctttcagatc ccaatcgcca agtgatcgtt gtttctgctt taggcaaacg tacgtcagat
     9781 gatgacaaag taacagactt actttatttg atttatgctt accttcagca tcatgttgat
     9841 tggacacccc tttggaaaag gatttgtgat cgtttcattc aagtaagaga tgttcttgcc
     9901 ctgcagttac ctattgaaga tgaactagca cgcatacaga aacaactgga agacgaaaag
     9961 ataactgaag attatttagt aagtagaggt gaatatctga ctgctcaact gatggctgag
    10021 tatcttggtt accagtttat tgacgcaaaa gacctgattt tctttgacta tgatgggaaa
    10081 atcgatcagg aaaaaacagc acaggaaatc acaaaagcat ttaaaagata tccgaaaatg
    10141 gttgttccag ggttttacgg ggcgaaccct gcaggaaaag aaaaattatt gggccgtggg
    10201 ggaagcgaca ttaccggcgc gatactggcg aagatgttgc aagcggaaag ttatgagaat
    10261 tggacggatg tttcaggaat catgatggct gatccgcgaa tcatcgatca tcctaaaatc
    10321 atcgaggaaa tctcttttag agaactgaga gagatggctt atatgggggc taacgttctt
    10381 catgaagcag ctgttttccc agttcaagag gctgatatcc ccatccaaat aaaaaatacc
    10441 aatgatcctt tcgctcaagg gacaaaaata tcgaatcacg aaatagaaaa ggaaaatgga
    10501 ctgacaggaa tagctggacg caaggatttt ctttccatca ctttattcaa acgtcatatg
    10561 tccgatgaaa tcgggtttat ctggaaagca atgagcattt ttgctaaaca tgagatatca
    10621 atcgaacata ttccttcagg gatcgacaat atcggagtga tcgtctcagc agaagcgatt
    10681 gccgataagt tatttctcat cacgaaagaa ttaaaagaaa cacttggcgt ggaagaaatc
    10741 gtcgtgatcg aagacttagc tttgatctct gtcgttgggg gtccgcataa agaattgatt
    10801 ggattatctg ggaaagtgtt atcgatattg aacaaattag aaattcgcac atcgatctta
    10861 tcacaaggag cacaggagtt gaatctgatc atcggtgtac cgaataatca atatgaaaca
    10921 gtagtgaagg gtatctatga agggatggtg aatacggatg ctgaaagaat atcgaatggc
    10981 actccatcaa attcctgaaa tcgggtttca tgaattcaag acaaaaaaat atttatatga
    11041 acaagtaaaa aacagcgagg ccgttatcca tgaaatcggc gaaacaggac tactccttta
    11101 ttttgataat cagcaagaag aaacgattgc ttttcgaaca gatatcgatg cactgccagt
    11161 caaagaagaa acgaatctct cttttgcttc taagcatgaa ggttatatgc atgcatgtgg
    11221 tcatgacgga catatggcga tgcttttagg gttgactgac tttataacta aacacattga
    11281 ggatcttatt tataatgtag tactgatcta tcagccatca gaagaaattt ccggtggcgc
    11341 acaaagcgtt attcagtcag gattgttgga taaatatgaa gtacaagcaa tatttggctt
    11401 tcatctatgg cctggactag ctaagggaga agttttctct cgaccaggac ctttgatggc
    11461 acaaagcagt gaaacagaca ttatcattaa aggccagtct gcacatattg cttctagtga
    11521 aaaaggaatc gatagtctgg aggcagctgt acgatttttg aagaatgttt atgattttga
    11581 ccggcaatta ccggcagagt ggaatcatct aatgaaattt ggccaaatcc aaggtggaac
    11641 gatccgaaat gttttagctg gagaagttat tgtatccgga agtatccgtt cttacagttc
    11701 agatatgcaa aattatttga agaggggatt agaccattta gcagaacagt ttcactctac
    11761 agctactatt tcttttcgct ataatgacgg ctatccagct gtaatcaacc atagaggctt
    11821 atatgcagca ctgttagatt caaacaaact acatgaatta gatgctccag ttcttcaagc
    11881 cgaagatttt ggcatatata cgcaacaata tccatgtgta tttttctttt taggtgtcgg
    11941 tgatacccct gctttacatg atccgacgtt cgattttgat atggatgttt tagaaaatgg
    12001 tgtagaatgg tacaaaacga ttctttttac agaaaatctt cttgtaaaaa tcgatagcag
    12061 ttcaaaagag gagcgagtaa ataatgatga atttatccaa tcgatttagt cctaggcttt
    12121 ctagaataga agtatcaaaa atacgacaat tcgatcagca aatatcgtcg ataccagatg
    12181 tgatcaaact caccctggga gaaccggatt ttccaactcc tgaacatgtc aagcaagcag
    12241 gaatagcagc gattgaagaa gacttttctc actataccgg aatgagagga ttagaggaac
    12301 tgcgggaagc ggcttgtata tttcagcaac agcgttatgg attaacttat gatccgcaaa
    12361 cggaagtttt gacgacagtt ggtgcaacgg aagcgattgc ctctgcgttg ttatctgttt
    12421 tggaagaagg agacaaggtt cttattccag cgcctgctta ttcaggatat cagccattag
    12481 tggaactagc tggtgctgaa ttgatcccga tagatacttc tgacacaggg tttgtctgtc
    12541 agccggaaca atttgaacga gcatttgaac aatatggatc agctgtcaaa gcagtcattt
    12601 taaactatcc taacaatcct actgggacga cattgtctgc aaaacaattg aaagcaatcg
    12661 ctgaggtttt aaaaaaatat ccggtatttg ttataagtga tgaagtatat gctgaattga
    12721 cttatagtgg aacgcatatg tccatagcta cttatcttcc agaacaaaca atcgtgataa
    12781 gcgggttatc caagtcacat gcgatgactg gttggcgagt gggctttatt tttgctcaaa
    12841 aagcccttat tgacgaacta attaaagtcc atcaatatct ggtgactgcc gctacaacga
    12901 tgtcgcaaaa agctgcggct gaagcgctaa taaatggggt gaaagatagc gagaatatga
    12961 aagagcaata tcaaacacga agagactatc tggtccagca attggcgcct ttaggatttg
    13021 aagtgaccca gccaaacggt gcattttact tgttttgcaa actcccagct gccattcaaa
    13081 ctgactcttg gcagttttgt gtagaattag cggaacaggc aaaagttgcg tgtatcccag
    13141 gaattgcatt tggcccagaa ggagaaggtt atatccggat ttcttatgct agcagcatgg
    13201 aaaaattaca tgaggcctgc aaacggatca aagacttttt aacagaacag tgattcatag
    13261 attttatcaa aaaaacaatc gttaattttg cggtatattc tgcaaggaga cgattgtttt
    13321 ttaaatttag ttcaaatgaa cgcgtttctt ttgattcata actaatgtaa tgttaagttt
    13381 aaattgttta gaatgatttt aaaagaatat tcaaggaggt ttcatcaatg gaaaaaatca
    13441 aagttgtcat tgtaggtgca tctcatggag ggcatcaatc gatcttggaa ctattgacac
    13501 gatacggtga aaatgtagat atcacgctat ttgaagcagg agactatatt tccttcatgt
    13561 catgtggtat ggagctgtat ttagaagaca aggtaacaga tgtaaatgat gtacgtaatt
    13621 tcagaccaga aaactttccg caatccaatg ttcatatttt aaataatcac gaagtaaaaa
    13681 cgatcgatgc cgataaaaaa acagtaacgg ttactagcgc atcagataac gaaacaaaag
    13741 aatatcctta tgacaaattg attttgagtt ctggtgtcaa accaaacaat ctgccagtac
    13801 caggagcaga tctagaaaat gtctacttga tgcgtggata caattgggca accaaaatca
    13861 aagaaaaatt aaatgatccg gctattaaaa aaatcgctgt cgtaggtgcg ggttacattg
    13921 ggatcgaagc agcagaagca agccgaaaag ctgggaaaga agtcgtattg cttgatgtga
    13981 tcgatagacc tttaggcact tatttagatg ctgagatgac agatatttta gaacaacacc
    14041 taaatgaaaa cggtattgaa gttttgacaa atgcaaaaat cgaagctttt actggtaacg
    14101 gaaaagttga ggcaatcaaa acaagtgaaa aagaaatccc agcagatcta gtcattcaag
    14161 ctgccggtgt gaaggcaaat acagaatggt taaaagggat cgtcgactta gatgaacgtg
    14221 gctggatcca aacaaatgaa tacttgcaaa cgaatcttcc agatgtgtat gcagtaggag
    14281 atgctacact tgcttattct atcccagcac gcaaaaaaat gccgatcgct ttagcgactg
    14341 ttgcacgtag agaagcacgt tatgtagtaa aacatctttt tgaagaagta ccaaacaaac
    14401 cgttcggcgg agtcgtaggt tcctctgcat taagtgtctt tgactatcat tttgcagcaa
    14461 gcggattgaa tagctttaca gcagcaaaag caggagtaga tgtacgagtg tcttattatg
    14521 aagatacgtt acgaccaaaa tatgtaccag aagaacaagg aaatccaaaa gtgtccatcc
    14581 aattattctc ggatccaatg acccatcaat tgctaggagg agcagtatta tctacctatg
    14641 atgttacagg tcaaggaaat gtattggcac tagcgatcca aaacaaactg actttagaag
    14701 aactagcaga agctgacttc ttcttccagc caggctttga ccgacaatgg agcatgttga
    14761 atctagccgc tcaacaagcg ttaggagaag aaccatttgt agaataagaa aacgaaatat
    14821 ttgaaaagag gttgtgaaaa agctgccttg catcaagtaa taagaacagc caagtaaaaa
    14881 cagcttctta tgtttttaac ttggctggac ttattaccgc agatgcaagc ttttgaacac
    14941 cgtttatttt caaaaaaggg actgtgacac gatttgtgta ccgaccccca aaagttagac
    15001 caaaaaatct aacttttgga ggtcggtatt ttttatggtt aaatatactt ttgaacttaa
    15061 attaaagatc gttcatgatt atttggatgg caaaggcgat tggaccgtaa aaatccagat
    15121 caagagattg aagcggaaat gcttaaaatt cgggagaagc acaaggatta tggctgttta
    15181 cggatgacca atgaactaag aaaccgcggt ttctctatca ataaaaagaa agttcagcgc
    15241 ttgatcaaga agctaggaat aaaagtaacg gcatacacgc gtaaatcacg tcgctacaat
    15301 tcttatcgag gaaaagt
//
LOCUS       DAMEEU010000065        15281 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.066, whole genome shotgun sequence.
ACCESSION   DAMEEU010000065 DAMEEU010000000
VERSION     DAMEEU010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15281
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.066"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(509..1075)
                     /locus_tag="PB779_002136"
     CDS             complement(509..1075)
                     /locus_tag="PB779_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HDE0739651.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1075..2031)
                     /locus_tag="PB779_002137"
     CDS             complement(1075..2031)
                     /locus_tag="PB779_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HDE0739652.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2031..2687)
                     /locus_tag="PB779_002138"
     CDS             complement(2031..2687)
                     /locus_tag="PB779_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HDE0739653.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3057..5075
                     /locus_tag="PB779_002139"
     CDS             3057..5075
                     /locus_tag="PB779_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDE0739654.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5145..5351
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5502..7916
                     /locus_tag="PB779_002140"
     CDS             5502..7916
                     /locus_tag="PB779_002140"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HDE0739655.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8264..9817
                     /locus_tag="PB779_002141"
     CDS             8264..9817
                     /locus_tag="PB779_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HDE0739656.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10198..11982)
                     /locus_tag="PB779_002142"
     CDS             complement(10198..11982)
                     /locus_tag="PB779_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739657.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(11997..13718)
                     /locus_tag="PB779_002143"
     CDS             complement(11997..13718)
                     /locus_tag="PB779_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739658.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13818..14579
                     /locus_tag="PB779_002144"
     CDS             13818..14579
                     /locus_tag="PB779_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HDE0739659.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
BASE COUNT         4976 a         2779 c         3003 g         4523 t
ORIGIN      
        1 tcttttttac tgctttgatc ataaaagtct gcatattcat cactgatatt ttttctaata
       61 aattcttcca tcataaaaat cacctcaaaa cgattatacg aacttacgtt cttgttgtaa
      121 agcgatattt gaggggcaaa aaaggggcat aatttgactg atattaagtt agctattgat
      181 atatgaatga catacaaaaa tataaaatct tttaaaaatg cttatatatc aatgtttttg
      241 ccattctttt atatatctgt tatatgtcaa aaaatgtgtt caatttcaat ttgtatttga
      301 ataaagaggt tgtgaaaaag ctgtcctgca tcaagtaata agaacagcca atcaaaaaca
      361 gcttctcatg tttttgattt ggttggactt attaccgcag atataagctt ttgagcaccg
      421 tgaataaaga ggttatgaaa tcaacgctct aacctgagta ttagagaaaa aaacgcaaaa
      481 catatcattt atgttttgcg ttttttattt atcttttttt ctcaatacaa tataaaatag
      541 gcggctggtt cttttggttg ataaaccgat aattcagcac attatatgtt tcctgtggca
      601 gtttggaaca aaaagaatca accatatcca gttctttttc tccaccttca tgaccatagt
      661 agacgacaag gatcaatcgt ccgcgaggca caagtcgttt caatatttct tccatagctg
      721 tgcgtgtagt ctctggcata gtgatgattg ctttatcact ttttgggaga taccctagat
      781 tgaaaatccc tgctttgaga ttttgttgtt cagctatcac ttctcctaac gtttcgtggc
      841 cttgtagaaa caatgagaca cgttcttcta actgacgctg ttctagcctt tcacgagtag
      901 catcgattgc ttgttgctgg atatcaaaac tatagacatg accagttttt ccgatgtgtt
      961 ctgctagaaa aaccgtatcg tggccattgc ccatcgttgc atctacgacg tgatcccctg
     1021 gttgcaagat ttcttgcagt aatgtatggc tgaaatgcaa agcagtttgc aacatcagac
     1081 gctcaccttt ttccgtacat catattttcc ttggaagcta tctctgcgaa gaagttcttc
     1141 atcaattgca ttcaagactt cccatttttt caagctccac attggtccaa tcaaggaatc
     1201 ccacggcgca tcccctgtca aacgatggat gatgatctct tttggtatca tttccagctg
     1261 gtcgcaaatg acattgacat agtcaggacg gctcattaat tgaaggcgac cttcatgata
     1321 gtcccgcaac attctcgttt tgcgcatcag atgcatcaaa tggagcttga ttccttggat
     1381 atctgaatct aaaatggtgc gtctgacatt ttctttcatc atttctaaac tttcgcctgg
     1441 taatccgttg atcaaatgcg tacaaacacg gatattatgt ttgcgtaatt tagccacgcc
     1501 atctaaataa gtttgataat catgtgctcg gttgatcagt tttgaagttt cttcaaaagt
     1561 tgtttgcaat ccaagttcta cccataaata catccgctcg ttcagttcag caaggtaatc
     1621 aactacttca tctggcagac aatccggtcg tgtaccgact gataatccta cgacacctgg
     1681 taaattgact acttgctcaa atcgttcttt gattatttca actggcgcat gggtgtttgt
     1741 aaaattttgg aaataaacga tgtattgttg gacatgaggc catttttgat gcatcatgtc
     1801 gatttctttc tggaattgga ttggaagagg gtcttcaggt gcaacgatca tgtctcccga
     1861 accagataca ctgcaaaaag tacaaccgcc atgggcaaca gtcccatctc gattcggaca
     1921 gtcaaatcct ccatcgatcg gcaccttgaa aattttcccg ccaaactcat ttcgtaaagc
     1981 gtaattccaa gaatgatatc ttttatttcc ttctgaataa ggaaaagtca ttaaaagtcc
     2041 ttctttctgt aagagttatc tatttgtttt cttttttctc tatacactgg ataagtcagg
     2101 cacagccaag aaagactgag taagtagccg ccgatgatat cagtaggaaa atgaacgccc
     2161 agataaatgc ggcttatccc gacacttact ataataaaca tcatcagcaa ttgaagcaat
     2221 gtgcgtaagg ttcttttttg aacaaaagct ggaagcagaa atagtaaaga accgtaaaga
     2281 atcatactgc ctgctgcatg tccactaggg aaactgtaac ttgtttcaac tactaagtgc
     2341 gccaatgaag gacgctctcg catgaaaaat agtttgatca ccgggttgat gattccagca
     2401 attacaataa atccagaaac gaaccaaaat gtttctgccc tttttttctt ataccacatc
     2461 cataaagccg cacaagcaaa taaaatgatg acggtaagag gattaccgaa tttagtcata
     2521 aagagttggt agctgttcag atcaggataa gaagctctga caatgcctgt aaaccactga
     2581 tcgaaaccag aaagccacga cagatggaac tttacgatcc agcccaaaat gaaaaacagg
     2641 acaagaaaga agctaccagc cacctgaaat gatgttttat atttcataca attcctcctt
     2701 tgaagcaatg acttattata gcatttttgg tccagcgaaa aaaacggtaa agagataaaa
     2761 ccaatgtatg attcctcttt gaataaccaa tattcttata aaaaaaataa ctgtaatcgg
     2821 aaagacattt tttggtaatg caaatgaaat gttagggaaa taaaatcagt gtttttcgaa
     2881 atccttttaa acaagaacgt agacgtagga agaacttgaa aatgaacaga agttgttcat
     2941 tacggtaaat tacaatatga ttacaaaaaa caacaaagct cttaaataac ttttaataaa
     3001 tattaagaga agttataatt attaataata gataaattga agttggagga tagaagatgg
     3061 aaaacattgc aagaaaagaa cggagacgtt tagaacagac caaacgtttt cgaaaagcaa
     3121 aacgaggggc agcaatcgtg ggaactgcga tggtaggctg ttctgtcgct gccccattag
     3181 tacagccggt tcctgttcaa gcggatgaaa cacctgttca gttcggcgca agaatcaata
     3241 cagcggcatt tatcacagaa attgctactt atgctcaacc aatcgctcaa gccaacgatc
     3301 tatatgcatc agtgatgatc gcacaagcag ttgtagaaag cggttggggc agtagtgcgt
     3361 tatctcaagc accttattat aatctttttg ggataaaagg cagctatcaa ggacaaaccg
     3421 tctacatgga tacgcttgaa tttttaaata atcaatgggt aaataaaaag gagcctttcc
     3481 gacaatatcc ttcttttgct gaatctttca atgacaatgc ctatgtactt agaaatactt
     3541 catttggcaa cggttattac tatgccggta cttggaagag caacacgaaa tcctatacag
     3601 atgcgacagc ttgtttgaca gggcgttatg cgactgatcc tggttacgca ggcaaattaa
     3661 ataatatcat cgcaacttac ggattgaccc aatatgatac accagctagc ggaaacgcag
     3721 gcggtggagc gactacaggt ggcaataata ctggaagtgc aggtagtact ggcggttcaa
     3781 gcaattctgg taatacaaac tcaggttcag caacttcgac cacttatact gtccaatctg
     3841 gtgattctgt ttggggaatc tcaaataaat tcggtatcac aatggatcaa ttgatccaat
     3901 ggaacaacat ccaaaacaat ttcatttatc caggacaaaa actgacaatc aaaggtagcc
     3961 aggaaaatgg ctcttcgacg aataattccg gtaacaatac caactcttca ggaaatgctg
     4021 gtacatcaaa cggaggacaa acaactggtg cgaaatacac tgttcaatct ggtgattctg
     4081 tttggaagat ctcaaatgat cacggaatta cgatggctca attgattgaa tggaacaata
     4141 tcaagaacaa tttcgtttat ccaggacaac agctaatcgt atcaaatggc ggttcttcta
     4201 atgctggagc aaatactggc tcaaatactg ggaatacaag tggctctagt tcgtccagct
     4261 caagttcttc taatacagct tcaggaacga aatatacagt taaagccgga gactctgttt
     4321 ggagcgtctc aaataaatac ggaattacga tggctcagct aatccaatgg aacaatatcc
     4381 aaaataactt tatctaccca ggacaacaac tgactgtttc aaacagtgga tcaacaaaca
     4441 gcacgtcagg taatacaggt tcgtcaacca atacaaataa cagcagttca gttaatactg
     4501 gcagcagttc gtctcaaggc acttataccg tgaaagcagg tgaatctgtt tggagcgtgg
     4561 caaataaaaa cggcatcacg atggatcagt taatcgaatg gaataatatc aaaaacaact
     4621 tcatttatcc aggacagcaa ttgatcgtta aaggtggaac ttcggcaaat acaaatacag
     4681 gttcaactac ttctgcagcg aaaccaaata caccgaatac gtctgctacg acaagtacat
     4741 catccactgg taatacgatg tataccgtga aagcgggcga gtcagtttgg agcgtagcga
     4801 acaaacatca tatcacgatg gatcagttaa tcgaatggaa taatatcaaa aataatttca
     4861 tctatccagg acagcaagtg attgtgaaga aaggttcatc tcaatcaaca aaccaacaat
     4921 cagttactgg ttcgaaaacc tatactgtga aatctggaga atctgtttgg agtgttgctg
     4981 acagtcatgg aattacaatg gctcaactaa tcgaatggaa caatattaag aacaacttta
     5041 tttatccagg tcaaacgttg attgtagcta aataaaatag ctgttcgaag aaataacgat
     5101 tgaattccac aaaaatattt gttactataa ggctacttaa atatgacaac acttgaaaag
     5161 gaagtagtaa aaagactgaa gtttcagaga gcgcatggct ggtgagaatg tgcacggatg
     5221 cttttgaact cgcctttgag ttgcccttgc tgaatacccg agtaagcaag cggcggtgac
     5281 ggccgttaca acgttcgagg ccttttcact aaggtaaaat taggtggtac cgcgtagatt
     5341 acgtcctata aaaagagcaa tctttttata ggattttttt atttcttttg tgaagtttga
     5401 gaaaacaaag caaaaggaaa taaaaataaa cagattctgc cggttttttc gttatattta
     5461 taatagaaac aagtgttttc aatagaacag gaggacagca aatgagttac aatcataaag
     5521 aaattgagaa aaaatggcaa aaatactggg caaaaacgaa tactttcaac acccatgatg
     5581 atcctgaaaa gccaaaattt tacgcactgg atatgtttcc ctatccatcc ggtcaagggc
     5641 tacatgtagg gcatcctgaa ggttatacgg caacggatat cctttcacgt gtgaaaagaa
     5701 gtcaaggata caacgtgctg catccaatgg ggtgggatgc attcggtctg cctgctgaac
     5761 aatatgcgct agatacagga aacgatccag ctgagtttac ccaaaaaaat atcgaaacat
     5821 tccgacgcca aatcaattct ttaggattta gttatgactg gaatcgcgaa gtgaatacaa
     5881 ctgatccgga gtattataaa tggacacaat ggatctttac gaagctttat gaaaaaggtc
     5941 tagcttatga agcagaagta gcggtaaact gggtacctga attaggaaca gttatttcaa
     6001 atgaagaagt gatcgatggg aaaagtgaac gtggtggcta tgatgtagtc agaaaaccaa
     6061 tgcgccaatg gatgctgaaa atcactgctt atgctgatcg cttattggat gatctagaat
     6121 tagttgattg gccagaaagc attaaagaaa tgcaaagaaa ttggatcggt cgttcagtag
     6181 gagcaaatat tgaatttaaa gtggctggta cggataaatc ctataccgta tttacgacac
     6241 gaccagatac tctattcggt gcaacttact cggttcttgc acctgaacta gatcttgtta
     6301 gagaaattac gacccctgaa caaaaagctg ctgtagaagc ttatatcgaa gagacagcta
     6361 aaaaatcaga tctaaagaga acggatcttg caaaagaaaa aacaggagta tttactggtg
     6421 cttatgcaat caatccagtt aatggcaagg aaatcccaat ctggatcgcc gattatgtat
     6481 tatcttcata cggcacagga gccatcatgg ctgttccagc acatgatgaa cgtgactttg
     6541 aattcgctca aactttcgga ctagaaattc ttccagttat cgaaggtgga gatgttgaaa
     6601 aagctgctta cacagaagat ggtacgcaca tcaactctga atttctagac ggcatgaaca
     6661 aacaagaagc aatcgataaa atgaatgaat ggctagaaga aaatggcgta gggaaaaaag
     6721 aagtcagcta tcgcttacgt gactggctat tctcccgtca acgttactgg ggtgaaccaa
     6781 tcccaatcat ccattgggag gacggaacag tcacagctgt cccagaagaa gagctaccat
     6841 tacggttgcc taagacaaaa aacatcaagc caagcggtac tggagaatct ccattagcaa
     6901 atatcgagga gtgggtcaat gtcgttgatc ctgtaacagg taaaaaaggc cgtcgcgaaa
     6961 cgaatacaat gccacaatgg gcaggaagct catggtatta cctgcgttat atcgaccctc
     7021 ataacaaaaa agaactagca gattatgaaa agttgaagcg ttggctacca gttgacatct
     7081 acattggtgg agcagaacat gcggtacttc atttactata tgcacgattc tggcataaat
     7141 tcttatacga tatcggtgtt gttcctacaa aagaaccatt ccaaaaacta tacaatcaag
     7201 gaatgatctt aggcgaaaac aacgaaaaaa tgtcaaaatc tcgtggtaat gtagtcaatc
     7261 ctgatgatgt ggtcgaaact tacggtgcag atacactgcg catgtacgaa atgttcatgg
     7321 ggccattaga tgcttcgatt gcttggagcg aaaatggctt agaaggaagc cgtaaattct
     7381 tggatcgtgt atggcgtttg atcgttgatg agaacaataa aatgcgtgac cgtatcacta
     7441 cattgaatga tggcaagctt gataaagtgt atcatcaaac agtgaaaaaa gtgacagaag
     7501 actatgaaaa tcttcatttc aatacagcaa tctcccaatt gatggtcttt atcaatgaag
     7561 cctataaagt ggacgctctg ccttatgaat atatcgaagg atttgttcaa ctactcgcac
     7621 cgattgctcc tcacatgggt gaagaactat gggcaatcct tggaaatgat ggtggtattt
     7681 cttacgcacc atggccaaca tacgatgaag cagcacttgt tgaagacgaa gtagaagttg
     7741 ttttccaagt aaacggtaaa gttcgtgcga aaagcaatgt tccccgagac ttaggaaaag
     7801 atgagctaga aaaagcagca ttagccaatg aaatagtgca agaatatatt gaaggcaaaa
     7861 cagtcagaaa agttattgcg gtaccaaaca agttagtcaa tatcgttgct aattaattgg
     7921 ctctttgtca ataaggactg atgagttgtg caaaatcaaa tctgggccag aatgaacttc
     7981 attctgtctc agattttttg ttatttcaaa ttgattaatt gattgatcaa aaaggttttg
     8041 attttcatgt tctcaaacac gttcaatgtc tttttcttct gaatggtctt gtaagagatc
     8101 tctgtaatca tcaaattttt gtctattaat cttagtattt tttgatgtat aaactacctg
     8161 aaattgagag tacataccaa attcataaat tttttattag tgggactagt gattgtatgg
     8221 attttgacgc ataatgaatg aagtatgaga aaaggagaga caaatggatc aagaactatt
     8281 tattatcgaa gtattatcag ctaaacaaaa aattatcgag aaagcgaaaa aaagagcgaa
     8341 aagaataatg ttcaagcttt taagcttagt atttttctct ggtttgcttt ttttcggagc
     8401 tgtatcgttc ctatatcgcc atatgagtgc agtagtccgt tcagctgaag ggatgcaaaa
     8461 attaaataat ttgtatcact tttcgtgggg agttggcgga ataacaattg ttgtgcttat
     8521 tgtttttctt ctacttattt ggctccgtta ccatcaattg tcgcgtcatt tcgatcaatg
     8581 gcttagtcaa agagcacaac agtttttaca taataaacca acttctcaag atgatgacta
     8641 tctttatttt gagaagactt cgacgagtca agcttttcgg atacaaaaaa gtgattgcca
     8701 gttattgctg agatcacttg atgatttacc tatctactta ggcgaaagca aatcaaaatt
     8761 cggaatgaac acattccata tttttttact agaaaacgaa cccagatggg aaaaaagcca
     8821 gtcttcgcct ggtggatacc tgacaactaa gatgagtaca ttagtcactg gttttttcct
     8881 cattctttta gctggaacaa tctattatgg gagatacact cagccaaaaa tgtcttctca
     8941 tataaatgct gcttctcaca tgacaatgaa ctcaactaac gatacgcata tacaaaagac
     9001 aaatgaaggg ttgttagctg atcctaagca aaaggtaaat ttgacaacac aaaagataaa
     9061 tgatctcaaa cttgatacag agacgcactc tctctatatg acaacagata gtggtgctaa
     9121 ttgggtattt gtgccgattg attcgcaatg gttgcgtttt ggcgaataca ccctgacaac
     9181 ggggctgatt cctgaaggtt attggatgga caacacatat gatatttccg ccgatttctc
     9241 atggtttatc tattcttctg gggatgatgt acgtctgctg acttcaagag ataatggtaa
     9301 aacatggcaa acgtctatta tcacccaatc agttcagccg atacgttatc gaaaagcggt
     9361 attttatggc aacgatggtc tatttatctg tacatcagcc agtgggatgt ctgcagaaac
     9421 tttgtacatt tacactacta tggatggcgg aatcacttgg ataaaaagtg gaagtacaat
     9481 gatcaatcag ccagtacaaa atgtcagctt cgttacaact tctttaggtt ttgtttcgac
     9541 acgtgaaagt ttgttttata caaacaacgg aggacgctca ttcaaagaat cagttctgtc
     9601 gattccggaa aactatcaga caggggggat agatcttttt caatcaccaa atgaagttac
     9661 tcaaataagc gcgaatacgt tagagacaaa attttatttg ttgaaaaaag gaccaatcga
     9721 tgcagggaaa atgtttgcct gcctcttccg ttcaactgat aacggggaaa catggcaatt
     9781 cgttcagcaa ctatcgcaag tagaacaagg agattaaaga agagagattg tgagcctgac
     9841 gttcagcacc gagtcacaag aaacaaattc aaaaaacagc ttctcatatt tgttgaatag
     9901 tgtaactcgt gattcggagt tgacaagagc aacaagaagc gattttgaag tatagcttct
     9961 cgtattttac aagatcgtgt cttattgccg ataggttgtc tcttgaacac cgtttattcg
    10021 taaaaaggga ttgtgacaag tcttttgtca ctacttaccg aacgaaactg aaggagctat
    10081 ccaaaaagta tcattagtat tattctttgt gtttctagtg gcaccactag tacatttaaa
    10141 aaagctatcg atcatggact aatcatacat gatcgatagc tttttagata atgtttgtta
    10201 cgctatctga aattgactat tataaagact ggcataaagc gttggtgatt ggagtagttc
    10261 agaatgtgtt cctttttcga cgatatcgcc attcttcatt acaaggatca tgtctgcatt
    10321 ttcaatcgtt gacaaacggt gtgcaatcac aaaacttgtc ctatcttttg tcacagcttc
    10381 cattgcttgc tgaatcaatg cttctgttcg tgtatctacg ctagaagttg cttcatctaa
    10441 aataacgaca ggaggattcg ctagaatgac tcgagcaatt gtcaataatt gttgctgtcc
    10501 ttgagataac gtgccgtttt cgctagaaat gatcgtatca tatccgtctg gcagtgttcg
    10561 aataaagtga tcacattgtg cgatttcagc cgcttcgata atttgttctc ttgtggcatc
    10621 cattttcccg taggcgatat tatcagctac cgttccttca aacagccagg tattttgtaa
    10681 aaccatccca aaagaacgac gtagttctcc acgtgaaagc ttggtaatat caagaccgtc
    10741 gaattcgatc tttcctttat tcagttcata aaaacgcatc agcagattga ctaaagtcgt
    10801 ttttcctgca ccagttggac caacgatcgc taccgtttgt tttggcttta ctgaaaaatc
    10861 gacttgattc atcaatattt tatctgatgt gtaaccaaac tgtacatttt tgaaagctat
    10921 ttttcctttc ggttgttcta aaagtcttgc atctggaagg tctggaattt catctgtttc
    10981 atctaatatc tcaaatatcc tatcgattgc tgccattgcg gattggatcg agttgatcac
    11041 ataagaagcg gtagaaattg gttcagaaat ctgattgatg tactgaagat aagcttgtaa
    11101 gaagccgatc gtcacaccac ctgatagaac aagcatagca ccgaataccg cacttatgat
    11161 gaaggcgagt tgattaatga aacgaatggc cggatagata gcacagttca taaattgagc
    11221 acgtttaaaa gcgttgtatt gctttttatt tacttcgtgt atagcagctt ctgcatgagc
    11281 ttgctgattg aatgttttga ccactagatt accagctaag atttcttcca ttcgattatt
    11341 taaaacaccc agttcatact gattctgttc agaaatctgt ttgtttttgt tcgcaatctt
    11401 agttgtaaca attgaactgc caacgatcag caataagacg agcaaagtaa gcttgctttc
    11461 gatataaaac agcatcagac cagcagcagc tattgttacg acagaagtaa aaaattgatt
    11521 gatacctgtc aataacactt gagaaagttg attgagaccg gtagttgtcc gactaatgat
    11581 gtcacctact tgatgattgt caaaaaacga catcggtaat gttttgaatt tttttgtgat
    11641 ttcttttcgc accctcaatg tgatcttttc gcttaacgct gccattgtcc gttcctgaat
    11701 aaatgaagtg atgctgctta agactgaaca gccgatcagc aataagacag ggaacaacaa
    11761 tgcttgtttg atatcactga aagaaagctg tccaatacct gtttttctta tttctgataa
    11821 gagatcatcg atcccgattc ccatgatcaa gggcatggct acgactaata ggttcccgaa
    11881 taaactgcat agaaacaatc cgtaaaaata tttatgttca ggtttgatca ttttccaaaa
    11941 acgtatcaaa gcacgcgtgt tcaacgtttt tttcttttcc atcgtatccc ttctttctat
    12001 attccttgtg attttgcaaa ctcctgataa gtttggcaat tagacagtag ttcttcatga
    12061 gtaccttgtc caacgatttt tccttcatct aaaacaatga tgttatctgc ttgttggatt
    12121 gtactgaggc gttgagcaac aatcacgaga gttttctccg acatgtgttt atgaagggct
    12181 gctcttaatg ctgcatctgt tttatagtct aaagcggaga aactatcatc gaatacatag
    12241 atctctgctg gtttgatcaa cgctcgagca atacatatcc gctgtttctg gccccctgaa
    12301 taattagaac cgccttgagc aacaaagctg tccaatccgt caggaagggt gtccactagt
    12361 tcttctaatt gagcgatctt gatcgcttta gacaactctt ctgttgaggc atattcattt
    12421 cccatctgca agttgcttaa aattgtcccg ctgaataaga aagccttctg agggacataa
    12481 ctgatgtggg agcggatctg ttcttgagtc atttgagtaa gaggaatacc accaagggtt
    12541 acttttccta tcgtagggtc actaagtctc aagagaagtt tcgccaaact actttttcca
    12601 gatccggtcc cgccaacgat cgctgttgtt tttcctttag gtattgtgaa atcaatatct
    12661 tctagaactg gatcagagat ttcagtatat ttaaatgtga catgttcaaa agcagctgca
    12721 tttgtctgat caaaggttgg ttcagctact gttttgatcg tctcttcctc aatttcgatc
    12781 tctgcttgca gtatttcttc tatccgtcgt aatgaggcaa acgatttagg gataatgacc
    12841 aataccatag ctgcgatcat caagtaagca agtgtcagca tagagtattc gactacagca
    12901 gtcacgacac cgatttgtaa tgctccttct gctacaagat ttccgccaaa ccacaaaata
    12961 gaagcataaa cgattcccat gagcaaaaaa gcaattggag tgacccaagc aaatattcgg
    13021 ttcactttga tcatttgatt agcatagtca gcaaagctct tattcgttcg cttttcttca
    13081 tatgattgat tatcaaaggc acggatcata ttaatcccag taaagaattc tctcaatgtg
    13141 atggtgatcc gatccatttt tggctggata ctcaaagata aaggtgcccc tcgtttcatc
    13201 agtcgataaa caatccatac ataaaaaaca acagagatca atgtaaccca tgttagtaat
    13261 agagaataac gaaacatcat gagaatggtg aaaacgcaaa taaccggtgc tggtaagatc
    13321 atttggcaaa ataaaacaat catttgctgg acattatcga catcattcgt cattcttgtc
    13381 aaaagagatc cagaactaaa acgactgata tccttcattg acagctgttg gaatttacgg
    13441 aaatatttct cccgcgtttg gaatccaaac ctagcggaag ccaatgctga aaagtaacta
    13501 gaggcaactg cagcgattgt tcctagaaac gctacaagca gcatttcaac tccaattttt
    13561 tttataactg aggcttcgcc acttgctata cctgtgtcga tcagctttgc tactaatttt
    13621 ggtacaccta atgtaccggc gatttctaaa cagatcatca caaaggtaag gagagcgagt
    13681 cctttgtttt tctgtaagaa tgtttttaag atagacatat tattcctcct tttttcctga
    13741 tacttttcga ttctatacct tcaagtaact tgaaggtcaa tagaaaaaag aataaactga
    13801 aaaagaggtg agaaaaaatg aaaaaaatgt atacgattgg ccaagtatcg gaactatttg
    13861 atttgccaaa atcaacgatc cgctattggg atgaacaagg attaatccgt tcaagtagac
    13921 aagaagagaa tgattatcga ttgtttgata tcgatgatat ttttatgctt tatgatatcg
    13981 ttttttatag aaaattagat ataccgatca aacagatgaa gaatttatat ggaaaaacat
    14041 tgacggagtt atatgagaca cttgatgaaa cagaaagaag aatccataaa gaactggtgg
    14101 tgatgaaaca aaaacaaaaa gagataaggg agcaaaaaaa acagttgaaa ttgatgatcg
    14161 atacaaacga ggaagaattt cctgtagaag agatcccttt tgactgtatg atctcaacgg
    14221 agtttgaaga tattgtggaa atcaaaaaat ttctacctaa ctattcaagc tttgggatga
    14281 tgagtatgcc agcttccagt tcacagacga tgtatggatt ttttatcgac cctagtgaag
    14341 tacatttatt tactcaagac gtgatttggg agaaaaaaga tacggctgtt tatcgtcgat
    14401 tcttattgaa atccgagatg aaccatgcgg aacgtaataa tattttagaa atcagagaaa
    14461 gaatgtatga aaaaggatgg aaaacaggag aagtgatcgg ccagtatcta ttgacgaata
    14521 cggatgaaaa caatatcaga actgaatatt atcatgcatg gatagaaatg aaaaaatagg
    14581 aaatatgtgt ttaagataac tcgaaaatga tggttgtttt agttataaag aaaaattttc
    14641 tggttcgatt acgggtttaa tgtgggggat tattagtcgt ggatagatag aattttagtt
    14701 ttttagagga aatatgtctt taaaaatgga atggttgcaa ttcttagcga tatatacgat
    14761 gtaattgtcc tcttaaaaaa gtatggaaaa ataattgtat tgggtgttat gtataattca
    14821 tggtgaactg agactaatga gaagaaaaat tcatattgtt atgagtgaga ttgtatcaga
    14881 tgagaatgat aaattaaata ggtgcataaa agcattacac ttaaaataca ttgttgctta
    14941 cattattaca atatgttaat aaggcaaaaa taaatagatg gattgaataa acatattttt
    15001 taatcaaata gtccctactg tgactttcct cagctatcgg tgatactacc gatagcattt
    15061 ttttgcttat aaaataatta taagtattta gagatttttc ttctaacatt cttcaaacaa
    15121 gaaaaatcac aaaggttatt gttattttta tatattcttt ttaagaatga ttgttttttt
    15181 atagaaattt taaaaaataa aacacgttat tgatggatag ttagtttgtt atttggtaat
    15241 attatagaag ttgactggta gtgatttatt tttcgtcgtt t
//
LOCUS       DAMEEU010000066        15185 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.067, whole genome shotgun sequence.
ACCESSION   DAMEEU010000066 DAMEEU010000000
VERSION     DAMEEU010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 15185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15185
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.067"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            1..531
                     /locus_tag="PB779_002145"
     CDS             1..531
                     /locus_tag="PB779_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HDE0739660.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(1014..1457)
                     /locus_tag="PB779_002146"
     CDS             complement(1014..1457)
                     /locus_tag="PB779_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739661.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(1473..2633)
                     /locus_tag="PB779_002147"
     CDS             complement(1473..2633)
                     /locus_tag="PB779_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HDE0739662.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            3140..4840
                     /locus_tag="PB779_002148"
     CDS             3140..4840
                     /locus_tag="PB779_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739663.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(4942..5775)
                     /locus_tag="PB779_002149"
     CDS             complement(4942..5775)
                     /locus_tag="PB779_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HDE0739664.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(6079..8244)
                     /locus_tag="PB779_002150"
     CDS             complement(6079..8244)
                     /locus_tag="PB779_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0739665.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            8504..10798
                     /locus_tag="PB779_002151"
     CDS             8504..10798
                     /locus_tag="PB779_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HDE0739666.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFELLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            10791..11456
                     /gene="pgmB"
                     /locus_tag="PB779_002152"
     CDS             10791..11456
                     /gene="pgmB"
                     /locus_tag="PB779_002152"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HDE0739667.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFSKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            11449..12456
                     /locus_tag="PB779_002153"
     CDS             11449..12456
                     /locus_tag="PB779_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HDE0739668.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            12478..13497
                     /locus_tag="PB779_002154"
     CDS             12478..13497
                     /locus_tag="PB779_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0739669.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(13778..15145)
                     /gene="nhaC"
                     /locus_tag="PB779_002155"
     CDS             complement(13778..15145)
                     /gene="nhaC"
                     /locus_tag="PB779_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HDE0739670.1"
                     /translation="MNKNISLKESIAVLIVLLALLGVLIIGFQLSPHIPILAAFMCLL
                     FYGRFKKFTWDEIHDGIIKGITPGIIPILIFLLIGVLVASWILSGTIPTIMVYGFKLV
                     SVRFFLPTAFLVCAIVGVTVGSSFTTISTIGIAFLGIGHLLGFNDAMTTGAVVSGAFL
                     GNNCSPLSDTTNLAAGIGGVNLFEHIAGMRYTDFPAFVLSLIFYTILGHNSHSADLAS
                     INEMIQNMKASFWISPWTLIPLVILFGGAIKKIPAIPTLLAGSTAALVLSFIHEKSLT
                     VGKAADILMNGYVANTPDPKLDELLSRGGIMSMLGSASLILLALALGGLLIKYLIVDT
                     IVQELKEKMDRPSRLVGFTALSCIGINLIVGEQYLSIILPGETFKRSFDDVGLSKTYL
                     TRTLADSGATVNSLVPWGVSGTFIMGTMKVSALHYLPFAFFSILAPVFTILGGFLLNR
                     RRVKN"
BASE COUNT         4656 a         3159 c         2776 g         4594 t
ORIGIN      
        1 atgaaagaat ttaaagaatt ggaagatttt attggaactc actttatcta tacgtatgac
       61 aatggttggg aatatgaatg gtatgccaaa aatgaccata ctgttgatta ccgtatccat
      121 ggcggaatgg tcaaaggccg ttgggtaaaa gaccaagaag ctgatatcgt taaattgacg
      181 gacggcgtat tcaaaatcac ttggacagag ccaacaggga cagacgtggc attggacttt
      241 atgccaaatg aaaagaaact tcacggaatg atctttttcc ctaaatgggt tgaagaacat
      301 ccagaaatca ctgttacttt ccaaaacgaa catatcgcag aaatggaagc agctcgtgaa
      361 aaatatgaaa cttatccaaa attacttgtt cctgaatttg ctacgatcac ttatatgggt
      421 gatgcaggta tagacaatga agatgttatt agcgaagaac catacgatgg aatgccagat
      481 gatatccgta gcggaaaata cttcgatgaa aattataaac gagtaaaata aggttgtgaa
      541 agagaggttg tgaaatcagc gttctgacct gagtattaga gaaagaaacg gaaaaatagt
      601 tcctcatgtt ttgccgtttt ttgagctaat accgagggtc agctgattga acaccgttta
      661 tcaagaggtt gtgaaatcag cgttatgctt tgagtaataa gaacgctagt tagaaaatag
      721 cttttcatat tttctaggct agtgggctta ttaccgagaa gcagccgttt gaacaccgtt
      781 tatcaagagg ttgtgaaatc agcgttttga cctgagtatt agagaaacaa atggaaaaat
      841 agttcctcat attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt
      901 ttatcaaaga ttgtaacaac tgcatattca cacagttaaa ttagtgactt caaaatgaaa
      961 taatgctccc agcaaaaaat taggctggga gcattatttc gttattctgt tcatcaaaaa
     1021 tcagcgtttt gattccattt catcacaagt tcctcctcat ttactgcttc atctttttgc
     1081 tgtgtttgaa ttgtaaaacc ttgtgaaaga tagaaatgaa tagctgattg atttttttga
     1141 tagactgtca aagtcagtgt tttattggtt tcttttattt ttttcattag ttgcgtaccg
     1201 attctttgtt gccggtattc ccttttcaca aagattcctg cgataaactg atcaatcacc
     1261 ccagcaaaac caataatttc ttgatctatt tctgctaagt aaatcactgc atctggtaaa
     1321 gctttcctaa cagattctac ttgattctcc caataagttg atggaatgaa ttcatgagaa
     1381 tccaagttag catgcagcca aatcgataga acagattcca gttctttggc agacaatttt
     1441 gttgttgtgc ggatcatttt ttctctcctt acttattcat tgattttaaa ataaaaacca
     1501 tttttttgaa gctcttttac aagttttcgc ccctcaaaaa agtatatctt ctcttgtttt
     1561 acttttctaa taccaaaaga aacagcaact ttaggatcat cagctgaaac gattcgataa
     1621 gttccaccag gcaattgatc cagcttgact ttcccatgat ggtcgctttg tactgaaaac
     1681 ggcacaccat ttctagtaag tgtttttttc ttatgtttca aaatgaatga actaccattt
     1741 accggtttcc ctgacgaatc actaataata aatgaaaaat caagcacttt tttacttaat
     1801 ctatactgat agattagtcg tccgataaac actaacagta tgactacagc tattatcgtt
     1861 cctgcaagaa taaaccattg ccgcatggtt ctttcctgat ttccttttcc ttcttctttt
     1921 tttaccgatt cgttataagg aatccgatgt cctgtcacta gcaaacgatg cgtgttgatc
     1981 atatacggcg tacatgtaag caaggtaact aagtcttctc cttctgaaat cgttagaaca
     2041 gacgtgtcat ctggcagtac cacttgtata tttttaactt gataagccaa tttctccccc
     2101 aaaacagtca aaataaacgt gtctccgttt tctaaacgat ctaattcggt aaataaccgt
     2161 cgattaggta aaccgctgtg agcagagatc actgaatgcg tcgaatttcc accaagcggg
     2221 aaagaggttc cttgcaagac gcctgctcca ttttcaagga tcctaccatt gagccgatca
     2281 taaagtgaaa tatttaattg gatcttaggt atattgatac ttccgatcag ccattcctct
     2341 aattggctgg atgttgtact ttcatttctg ttcttttcat tgaaaggatc agtaccagga
     2401 ttgaatcctt ggtcagttaa tcgttggttt ttctcctcca ttttctttcg ctgcacttca
     2461 atttcagctg cggtccgttt ttgtacttgt tcgatacgtt tttgatcaat aaaactattt
     2521 aaagaatcca cataaaatgg atataaagcg atcagtaacc ctacgacgat acatattaat
     2581 aaaaacaaac gaaacaaaag tcgacgagac tgtttttgct tactctgctt cacatgtgtc
     2641 ctcccttgca agtttttttg ttctttcttt tattatatgg gttcaggaaa aaaatagaaa
     2701 atgaaagccg atgaggttgt gaaaaagctg tcctgcatca agtaataagt acagcccaaa
     2761 aaaatagcta ctcatatttt ttgttgggtt gggcttatta ccgcagatgc aagcttttga
     2821 acaccgttta aggaagaggt tgtgaaaact gcgttatgct ttgagtaata agagcgctag
     2881 tcagaaaata gcttctcata ttttctaggc tagtgagctt attaccgaga agcagctgat
     2941 tgaacaccgt ttaccgagag gtcatgaaaa agctactttg tttcgagtat taagaaaaat
     3001 tctgtttcaa aacaaggaga tgcaacaaaa cttatgtcgc atcctctctc cttagaactt
     3061 tcacttatgt ttttcttgta aaattcataa atattttcat gaattttcta atttcttgcc
     3121 tacctctcgc ataggatata tgatgaattt atctaaagtt tgcaaaggag ttcgacaatt
     3181 gaaaaaatat ggcccatttt tagcaatttt tttcattgct ttggcatttc tcatgcctca
     3241 tttattcaca cataaactaa ttttgggtgc tgatgcccca ttccattaca atcggttcta
     3301 tgatgccgcg caacaaatta aatatgggga tttccattat tttccttccc tttatggatt
     3361 ccagcaaagt ggcaggatcg tgaatgccgt ttacggccca tttttcgctt atttacaagg
     3421 attgatcgtg ttgcttgcag gtagctggtt tcattatcag attctttcaa atttcattct
     3481 ttatcttatt tcaggatttt ctatgctgat tttactgaga tatgtcaatg ttcgaaattg
     3541 ggtaagtgta ccagtagccg ttttattcat gagtacgtat tctattcaat actggtctat
     3601 caaccaagga ttcactagct gggggacttg tttttatcct ttatgtatga tccctattgc
     3661 tgatttcgtc cttcataaaa agttccctgt tatcaaagtc gctgtctcag tgggacttat
     3721 gacacagatc catttactgt cttcgatcat gttagctttg atgtatatcc ctttttatct
     3781 ttattacttt tttaaccaga ctgaaaaagg aaaagcactg cttcaactga ttaagtcggt
     3841 cttgctttat tttgttctga cagcaaatat ttgggcagga ttagctattg tttacagtgg
     3901 gaataagatt cttcctccct ttgttaacag agaaatgagt caaaaggcga tagatctgga
     3961 tggcagttat tggctccatt accctaaggc ctttcctata ttgatattat caggtttttt
     4021 gctttttatt ttctttcaac aaaagaacac cttattccaa aaaatcgtgt tgtacacaag
     4081 tcttgttttc ttttttcttt ctactagctt gattccatgg acgacattga tcgaaaaaaa
     4141 tgtgcctttt attagtttga tccagtttcc atttcgattt ttcgtgccat ttacgctatt
     4201 gcttctactt taccttgccc tttcactgaa ccagtggtct gaacaaaagt ggttccgtct
     4261 tttaagtata tttggcattc ttattttttc agcacagacg atccagaact tataccagca
     4321 tctggaaaag tgggaaaatg aaacatttgt cagtcgacat acttatctat tcgatacgcc
     4381 ggaagaagca aggaaaacat tcttcagcaa agatatgtct accagcttgt tcgttttcca
     4441 aaaaaccaca cctgactatc tgccaatcta taaggagaca aaagacaata aatacgaccg
     4501 gtataacgaa gaaatactag aaaacgaaac aacttttata aaaacacatc caggcggtct
     4561 tttgacaatc aagtggaaaa acactgggga caaaactgtt catatccctg ttatcgtcta
     4621 cgatcggact gtgctacagc aaaatggaaa aacattgact gattatgaag taacagatat
     4681 cgggacccca atcgtgaagc agcaaaaagg aatcaacgag ctcacgcttc attatcaaac
     4741 gccaatctat ttctatttca ttctttctct tactttgatt ggctggttta ccttgctatg
     4801 tttatttatt tatcatagat acaagctttt acgtgcttag gcaaaaggga taaatacatc
     4861 cgatcaaaaa actctccaaa cggtataatc gtttggagag ttttatttta atcagttttt
     4921 ttatgttata tgttatattt tttattcgtt cacatctaat tcgatttcca ccccgtagtg
     4981 atcactgatg attggactat cgatcccatc aaaaatccgt tgatattttt taacctgcat
     5041 tccttcaggg acgaaaataa aatctatacg caatttttct gtattttgtt cccaaccatc
     5101 tattttcttt tccacagtag ctgcttttcc tttttcattc gcgacaacat acgaatcttg
     5161 aagaagaagg caactttctc ttacagtata ataaccttga gagtctactg gattattgaa
     5221 atcacctagg aaaaaaagtg gtacgcgagt ttccaaaaag tagttttcca agtttttcca
     5281 ctcaaaataa aagccacttt ttttatctgt ccaccaagaa aagtggcagc tcgagacaaa
     5341 aatgtcctga tcatctatct ttgttttccc aatcaagatc ttgcgtgtct gataatcttc
     5401 tttcttttga aattgggaga cggtaaggac ctgactttcc aatgtttttt tcgtaagcag
     5461 tgcatttcct tcttcatatt tatcataacc gatgtggctc atttcccaac tccaaaaata
     5521 ctcttttccg tgttccttta aaagctgaac taaacggtag gcaaaattat ctttacggat
     5581 aggtacttga ttctttaccg gacagaactt cattagcttc gcaggttcta cttcttcaga
     5641 ttccagtaat tggttgattt cttgtaaagc aatcacttca taatcttcta acaggatctt
     5701 atctgctaat tcttgcaatt ttttctctgg ttctggctca agccagctat gcgtgttgag
     5761 tgtcatgaat ttcattggtt ttctccttgt cttcatttcg aaacaaaagg gttgtgacaa
     5821 aatttttgtc acaacctctc cagcaaatag tgttctcctg ctaactcctc agtaataagc
     5881 tcaatggacc aggagctatt ttttgtttgg ctgtttttat cacttggtgc agggcagctt
     5941 tttcacgacc tctccactaa acagtattca aactgctgct tctcggtaat aagcccaacc
     6001 aaacgaaaaa taggaggagc tatttttgtt tggctgttct tatgacttga tgcaggacag
     6061 ctttttcaca acctctcctt acattttaat ggagccgatc actttaccag ctgtcactgt
     6121 acctaattgc ttgatcacta cttcttctac tttatcgttt gtaaatacga tcatgatcgt
     6181 tggatctttt tcttcgtttt ggatcacatc aagatccatc tcagctaatt tcgttcctgt
     6241 tcctacttct tggccttctt tgacagcaat ctcaaaagct ggctgattca tttggactgt
     6301 atcgattccc atatggatca aaacttcgat accatctttc gtttccagcc caattgcatg
     6361 tttgctaggg aaaatacttg tcacttttcc agcgatcggc gcaacaactt ctcttgatgt
     6421 tggaataaca gcaaagccgt cacccatcat tttttgtgag aataccggat cttttacttc
     6481 agataaagga atcacttctc cagaagctgc ggaaactagt tcttgttcta tacctaagta
     6541 ttgcttacta cctgcttgtc catttcctgt agaaaccatt tctggctctg gaatctctgc
     6601 tcctgattgc agcagatctt cgatatctga tttcaagaca tctgcttttg gtccataaac
     6661 tgcttggact ccattgtctt tgacgatcaa tcccatcgcc cctgctcgtt tccaggcttc
     6721 ttcagtccct actttttctc gatcatttac acttacgcgt aaccgagtca tacaagcatc
     6781 gacatctttg atattttctt ttcctcccag caaatgaatg atctggacca cttgctgatc
     6841 tgctgttcct gttccgctgt tagatacaac ggtttcttca ctgtcattgt cgtaatttcc
     6901 gttacgtccc ggtgtagcaa agttgaattt tttgatcaag aaatttgcta agaaatacgt
     6961 aacaacacca aaagcgatca cacacaacac gaagttgata agatctccac ctagacccgc
     7021 tttgatagct aacggtgtcc gagtcagcaa ttcgatattc ccaaatgaat ggacccgcaa
     7081 tggcaagata tctgccatcg caaatgcagc cccttggatc actgaataaa tgacatataa
     7141 tggcacagca gcaaacataa acatgaactc caatggttct gttacacctg ttagaaagac
     7201 agccaacgct gctgaaaaat acattgattt atatcttgct ttcttatcag gatcgacatt
     7261 acgatacatc gcaaaagcca ttcccatcaa gatacctgaa gaaccaatca tttgtcctac
     7321 tttgaaacga gccggcgtcc agttatgcaa cacaaactca tattgcgaca tatcccctgc
     7381 acctttaaga ttcactaaat cagtggccca agccaaccat aacggatctt gcccaaatac
     7441 ttgtgtcccc gcctgtgcgc ctgataaaat ctcatacgat ccgccaagct gtgtatagtt
     7501 gataggaatc gtcagcatat gatgcaatcc aaatggcaat agtaaacgtt ctaatgttcc
     7561 aaataaaaac ggtgctagaa tcggtgcgct ttcttgtgat tctgcaatcc ataaaccaaa
     7621 attattgatt ccagcctgta cgtttggcca caccacagca agaatcaatg ccacgattgt
     7681 tgaccataag ataacaacaa acggaacaaa gcgctttcca ttgaaaaatg acaaagcatc
     7741 cggcaatttt ctataattat agtacttatt ataagccatt gccccgacaa atccagcgat
     7801 gatccctacg aatactccca tattcaaagc tggtgcttcc aatacacttg taaaaaatcc
     7861 tttaaccatg atcttcgtac cgaacagagt gtgggtaaat gcatcttcat tcgcaagcat
     7921 gtcacttgtg acaccaaaga tagccccagt gatccgattg attaaaataa atgagatccc
     7981 agctgcaaat gctccgcctg ctctttcttt tgcccaactt cctcctattg ctaaagcaaa
     8041 taaaatatga agattaccaa taattgccca accaatattt tcaattactc cgcccgttgt
     8101 gacaagcggc gtccaatcag gattgatcaa gggaattgat ttccctatac tgatcatcaa
     8161 cccagctgcc ggcataactg ctaccacaac cattaaagcc tttccaaatt tttgccaaaa
     8221 ctcaaaacta aatatctttt tcattccgtt tagctccttt acgcaatcgg tttcgttaaa
     8281 cgtattatag cgtgcgtttt cttttttgta aatgctttat tttttatttt tctgtctata
     8341 ccattctata aaacctataa tacgtgtgtt cccttctata attttctcct aaaaatttat
     8401 ttttttaagc ttttttctat gaaatatttt cttttgtcta ttgacttgtg caatcggttg
     8461 cgtttattat gaacgtataa aacagctcat taggaggaga aaaatgaaac agatcaaacg
     8521 actatttgct attgatccat ggaaaatcag cacgacacaa ttagataaaa aaaatcttcg
     8581 actgcaagaa tctttaacaa gtattggaaa cggttatatg gggatgcgcg ggaactttga
     8641 agaaacttac tcaggggacc accatcaagg tacttatttg gcgggtgtct ggtatcccga
     8701 taagacacgt gtcggctggt ggaaaaatgg ttatccagaa tactttggaa aagtgatcaa
     8761 cgccttgaac tttatcgcga tagatatttc gatcaacgat cagctgatcg acttggcttc
     8821 tttggaacca gaagactttt actgggaatt agatatgaaa aatggtgtat tatctcgtac
     8881 attcacaatc actacttcta ctaataaagt acgcatttcc ttcgaacgtt ttctgagcat
     8941 tgtcaaaaaa gaatcagctt atatctattt aactatagaa atgcttgaag gtagcggaac
     9001 agtcaaactc gtatcaaaat tggatggaaa tgttcaaaac gaagacagca actatgatga
     9061 acatttttgg aatgagattg atcgtggaac tatagaagaa atcggctatt tgacgactaa
     9121 aactattcca aacaactttg ggattgaaca atttactgtt actgcagcaa tgcgccattt
     9181 cgttaatgga aaatcagtca tccctgacta tcacgaagat actttagcat tacatggttg
     9241 cttgtctgca gaattatctc aaggtgagac atggtcagtg gaaaaagaaa ttatcgttct
     9301 tactagtaga gatattccag aagcgcagca agcagaaaaa gctgtctcag aattaacgaa
     9361 ccagacaaac aattatatcc aagcaaaaga agagcaaaca gcggcttggg cagaacgatg
     9421 gaagcttgcc gatgtggtca tcgaaggaga cgaagaagca caacaaggta ttcgattcaa
     9481 tttgttccaa ctattctcta cttactacgg cgaagatgaa cgattgaata tcggccccaa
     9541 aggattcaca ggagaaaaat acggcggagc cacttactgg gatacagaag cgtatgctgt
     9601 ccctctttat cttgctttag ccaaacctga agtaactaag aatctgctga aatatcggca
     9661 taatcaactg ccgcaagcaa tccacaacgc tcagcaacaa ggattaaaag gcgcgcttta
     9721 tcctatggtc accttcactg gtgtcgaatg ccataacgag tgggaaatca cattcgagga
     9781 gattcaccga aatggcgcga ttgcctatgc aatctacaat tatacgaatt acaccggcga
     9841 tacggaatat ttgaaaaatg aaggactgga agttttagca gaaatcgcac gcttctgggc
     9901 agaccgtgtc catttttcaa aacgagcaaa taaatacatg atccacggtg tgaccggccc
     9961 aaacgaatat gagaacaata tcaataacaa ttggtataca aatacgatcg cagcttgggt
    10021 cttgcgttac acgcgagaaa attatttaac ttatcaaaaa gaagctgcta tcactatcag
    10081 cgaagaagaa ctagccaaat ggaaagatat cgcagagaac atgtacttcc cagttgacga
    10141 agaattagga atctttgtcc agcatgacac attcttagat aaagatctca tgcctgtatc
    10201 cgatattccc acaagcgatc ttcctctgaa tcagcattgg tcttgggaca aaatccttag
    10261 atcttgcttc atcaagcagg cagatgtact acaggggatt tatttcttca atgatacttt
    10321 tacaaaagaa gaaaagcaaa aaaactttga tttctatgaa ccaatgactg tccatgagtc
    10381 ttccctttcg ccaagtatcc attcgatttt agcagcagaa ttaggaatgg aaagcaaagc
    10441 tgtagaaatg taccagcgaa cagctcgctt ggatttggat aattacaata acgacacaga
    10501 agacggcttg cacatcactt ccatgactgg tagctggttg tcgattgtcc aaggatttgc
    10561 tcaaatgaaa actgcccatg atcagttgag attcgcacca tttctgccaa aaacttggaa
    10621 agcttattct ttccatatca attatcgcgg acgtttattg ttcatctcag tcacagatga
    10681 acaagttact ttcgagttat tagaaggttc tcctctagaa atttacgtct atgaacagtc
    10741 ttattcttta gcggatcgtc tagaaataac gctaagaaag gaggaagcaa atgtttaaag
    10801 gggtattgtt tgatttagac ggtgtcatta ccgatactgc tgaattccat tatcgtgctt
    10861 ggcgaaagct tggtcaggaa atcggcatta cgatcgacca cacattcaac gaacagctaa
    10921 aaggcgtcag ccgagaagac tcactctctt tgcttttagc ttatggcgga aaagaacact
    10981 ctttttcaaa ggaagaattt gcagaattag cgaaaagaaa aaacgattat tatttagaga
    11041 tgatccagac gatcgaacca aaagatgtct tccccggggt cgtgccttta ctggattctt
    11101 taaaagaaga aaaaatcaag attgctcttg cttctgcaag taaaaacggg ccattcctac
    11161 ttgaaaaaat gggtcttaca ccttactttg atgctattgc cgacccggca gaagcaacaa
    11221 acggaaaacc tgcgccagat atcttcctcc ttgcagcaaa agctgtcgga ctaaaagcag
    11281 aagaatgtat cgggatcgaa gacgcgcaag ccggtatcca agccatcctc tcaagtggcg
    11341 ctcaaccaat tggcgtggga cgtgctgaag accttggaga ggagatcccg cttgtccctg
    11401 atacgacttt tcttacgatc gattacttga aagaaaagtg gcatgaccat ggataatcca
    11461 gagatctccg tcgtaccagt tccagagact gaaataaaga aaatcacatt gaagaacgac
    11521 tacttagaag tcgttcttct caattacggt gcccgcctgc accaaatctt cgcaccagac
    11581 aaagaaggaa aatcagaaaa tgttttattg tcttacgatc gtttcgaaga tgttctaaca
    11641 gacaaaagct tttttggagc aactgtcgga cctgtagccg gaaggatccg ggatgcttct
    11701 tggggtgagc atagattgga gaaaaactgc ggatcacacc atatccacgg tggcacgaaa
    11761 ggctggtctt tccaattttg ggaagtagaa gttttcaaaa ctccatcatc aataggtgtg
    11821 gtcttttact taaaagatga attttctacc tatccaggac caatcactgc tacgatcact
    11881 taccgtttaa caaaaaacga attagagatg acaacctctg ctagtagcct tgttgaaacc
    11941 atctgcaatc cgaccaacca tgcctacttc aacctttcag gaaatggaac aagagacatc
    12001 tatgaacatc agttaacggt ctttttagat ggtgtgcttg aattagatca agaaaaactg
    12061 cctactggaa attggacaaa aaaagaaaaa ctgccaatcg actttagaaa atccccaaca
    12121 ctgcaagaga tccttgcatg ttatccagat ggactagatg atgtatttct tttgcatcat
    12181 cctaggcttt ccaaaacttc cttacaatta ttcgagaagc attctggtcg ccaaatgact
    12241 atagcaactt ctaataaaag tatggtatta ttttctacga ctggattcga agctgatttc
    12301 tctgtcaatg gaaaacagat gcattcaaac tacggattag caatcgaacc gcaagaaatc
    12361 cctgatatcg ttcatttccc caaatttgga tcgatcaacc tccatcctgg tcaagaacgg
    12421 atcagtcaga cgatttatcg gttctctgca caataacaag agaaaggtgt ttttatcatg
    12481 gctattaccg taaaagatgt ggcgaaaaaa gccggtgttg ccacctcgac cgtctctcgt
    12541 gtcatcaacg atcatcctag tatttccgag acaacaaaga agaaagtccg aaaaattatg
    12601 gatgaactag gttatgttcc taacatgact gcccgcaatc taggaaaacg catttccagt
    12661 gccatcggcg taatcttacc ccctcttgat tcaaaagagc ggatcggtaa cccattttat
    12721 cttgagatca tggaagcaat caacgaagaa gcgcggaatt atgatatgac tacagcaatc
    12781 gctactgcta aaaattttga attgctgtta gagaacgtcc agcgtatgca tttacaaaaa
    12841 caagtagatg gttttattct agtgtattca gatagtcaag atactgtcat tgattattta
    12901 taccaaaacc acatcccttt cactttgatc ggacagcctt atcatcatga gaacgaaatc
    12961 gtttatgtag ataatgataa ccagcttcta ggtaaacaag caacagaatt tttgatccag
    13021 aatggacata agaatatcct gtttgtgaca aacacgactc atgaaagttt gtatttcgaa
    13081 cgatatttcg gttatcaaaa agcaatgatg atggctggtc ttcctgcgtt atccagtgta
    13141 gtactagagc atccggagga ttatctgtcc tttgagaaaa cgttgaaaga aaacgaagcc
    13201 acagcattgg tggtcattga cgatatcttc gcccttcgca cgatgcagtt ggcgcaaatg
    13261 tatggctatg tcattccaga gacactctcc gtcattagct tcaacaactc gatcttctca
    13321 acattaacac acccttacct tacaagtatc gatatcgata tctccgaatt aggacgtgtc
    13381 gctatgcaaa agctgcgcga attgatccat gaagaattga gcagtggcgt acgtttggtc
    13441 atccctcatc gcttgatcaa aagagagaca gtcgttcctt tagaaaaccc atactaaata
    13501 gctgactcac taaatacgct gaccatttat cctatggtca gctttttatg taaaagaaga
    13561 tactacttct aacacattgt ttatctgtaa aaaagagcgt gggacaaaag taaagaacac
    13621 ttttgtctca cgctctaaac acgtataaac ggcggaagca gaagcaactc cttcggaaat
    13681 aagctgaaat tcacaaaaat ttaaaaagca attttcttga gtttcttctt atttcttgga
    13741 gttaaacgct tctgtcccag cctctttttt ccttccttca attttttaca cgtcgacgat
    13801 tcaataaaaa accgcctaat attgtaaaga caggtgcaag aatcgagaaa aaggcgaatg
    13861 gcaagtaatg caacgcgcta actttcatcg ttcccataat gaatgtgccg ctgactcccc
    13921 acggtacgag agaattgacg gtcgcacctg aatccgctag tgttcgtgtc aaataggttt
    13981 ttgataagcc aacgtcatca aaagaacgct tgaatgtttc tcctggaaga atgatggaca
    14041 gatactgttc tccaacgatc agattgattc cgatacagct caaggcagta aacccgacta
    14101 aacgagaagg tcggtccatc ttttctttta attcttgaac gatggtatca acgatcagat
    14161 atttgatcag taacccacct aatgccaatg caagtaaaat caaactagca gaacctaaca
    14221 tactcatgat cccgcctcga gaaagcagtt catctagctt tggatcaggt gtatttgcga
    14281 cataaccatt catcaagatg tctgctgctt ttccgaccgt caaacttttc tcatggataa
    14341 aagaaagaac gagagcagct gtcgatcccg ctagtaatgt agggatagcc ggaatttttt
    14401 tgattgcccc cccaaataaa ataactagtg gaatcaatgt ccaaggagag atccaaaagc
    14461 tcgctttcat gttttggatc atttcattga tactagctag atcggctgaa tgactgttat
    14521 gtcctaatat cgtataaaaa atcaacgaaa ggacgaatgc tgggaaatcc gtataacgca
    14581 taccagcgat atgttcgaat agattaactc ctccaatacc cgctgccaag ttggtcgtat
    14641 ctgataaagg cgagcagtta ttccctaaaa aggcaccgga aacgactgcg cctgtagtca
    14701 ttgcatcatt gaatccaagt aaatgaccga tccccaaaaa agcaattcca atcgtcgaaa
    14761 tcgttgtaaa tgaactgccg acagtcactc cgacaattgc acaaacaaga aatgctgtcg
    14821 gtaaaaagaa acgcacagaa acaagtttaa atccataaac cataatcgta gggatggttc
    14881 cagataaaat ccatgaagca actaagacac caatcaaaag aaaaatcagg attggaatga
    14941 tccctggagt gattcctttg atgatcccgt catggatctc atcccatgtg aactttttaa
    15001 atctgccata aaacaacaaa cacatgaaag ctgcaaggat cgggatatgt ggcgagagct
    15061 ggaatccgat gatcagtact cctaggagtg ccaacaacac gatcaataca gcgatacttt
    15121 cttttaaaga aatattttta ttcatcgtcg atctcctatt tcaaatgaaa aggccctgcc
    15181 atgaa
//
LOCUS       DAMEEU010000067        14993 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.068, whole genome shotgun sequence.
ACCESSION   DAMEEU010000067 DAMEEU010000000
VERSION     DAMEEU010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14993)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14993)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14993
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.068"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..607
                     /locus_tag="PB779_002156"
     CDS             <1..607
                     /locus_tag="PB779_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739671.1"
                     /translation="ENQLFAGDVLEIVLNDQAGEAAAKGVQNKPSTNDEIGNHNPSDT
                     PVVYHDAPPFAPATKIVVEGGLSFLAPSKLDCGQIKATGLTQEAFGQMDIQEKLWIYD
                     QRETKSPWILTIKLSQPFTTDAGFSMQDVLYFKKAEEYQLVNEEELEIVRGQNSTNVQ
                     TDYSEYLNNGRAFKLVLTKENQIAGNYSAEMTWTLADAPTE"
     gene            627..1655
                     /locus_tag="PB779_002157"
     CDS             627..1655
                     /locus_tag="PB779_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HDE0739672.1"
                     /translation="MNRIWNKSHRNNCSLLLILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILIRNSEKESSPNLKLKKTYADQSDGRNVIKANLQNPNAS
                     YMFGLTTSVEIYKKETKEPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKG
                     AWKEKRWNLHTDFEITDDAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFI
                     LKERRKKK"
     gene            1652..2410
                     /locus_tag="PB779_002158"
     CDS             1652..2410
                     /locus_tag="PB779_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HDE0739673.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPNEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QNGTDSTGTATQVQNFVQVTDKSGIYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGTPSTISGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEGKA"
     gene            complement(2496..3236)
                     /locus_tag="PB779_002159"
     CDS             complement(2496..3236)
                     /locus_tag="PB779_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0739674.1"
                     /translation="MKKYFIIEDNQFHSEWIIKELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            3297..4550
                     /locus_tag="PB779_002160"
     CDS             3297..4550
                     /locus_tag="PB779_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HDE0739675.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGFIALMVVTLL
                     FPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGLRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            4851..5099
                     /locus_tag="PB779_002161"
                     /pseudo
     CDS             4851..5099
                     /locus_tag="PB779_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877177.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            5221..5547
                     /locus_tag="PB779_002162"
     CDS             5221..5547
                     /locus_tag="PB779_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HDE0739676.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLQLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEF"
     gene            5615..6328
                     /locus_tag="PB779_002163"
     CDS             5615..6328
                     /locus_tag="PB779_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HDE0739677.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYLVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PIFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEEKEIVTLITCGDMDAVTRLVVQGELESVTP
                     IKDATDDMRSAFNLETKTF"
     gene            6638..7490
                     /locus_tag="PB779_002164"
                     /pseudo
     CDS             6638..7490
                     /locus_tag="PB779_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            7611..9476
                     /locus_tag="PB779_002165"
     CDS             7611..9476
                     /locus_tag="PB779_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0739678.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            9524..10933
                     /locus_tag="PB779_002166"
     CDS             9524..10933
                     /locus_tag="PB779_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HDE0739679.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            11041..11742
                     /locus_tag="PB779_002167"
     CDS             11041..11742
                     /locus_tag="PB779_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739680.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            11901..12380
                     /locus_tag="PB779_002168"
                     /pseudo
     CDS             11901..12380
                     /locus_tag="PB779_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            13228..13803
                     /locus_tag="PB779_002169"
     CDS             13228..13803
                     /locus_tag="PB779_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HDE0739681.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            13803..14243
                     /locus_tag="PB779_002170"
     CDS             13803..14243
                     /locus_tag="PB779_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDE0739682.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            14259..14960
                     /locus_tag="PB779_002171"
     CDS             14259..14960
                     /locus_tag="PB779_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HDE0739683.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         5066 a         2484 c         3161 g         4282 t
ORIGIN      
        1 agaaaatcaa ctttttgcag gagatgtatt agaaattgta ttaaacgacc aagcaggaga
       61 agctgctgct aagggtgtgc agaacaagcc aagtaccaac gatgaaattg ggaatcacaa
      121 tccaagtgat acgccagttg tttatcatga tgccccgcct tttgcacctg ctacgaagat
      181 tgtagtagaa ggtggtctct catttcttgc cccttccaaa ctcgattgtg gtcagatcaa
      241 agcaactggg ttgacgcaag aagcatttgg ccaaatggat atacaggaaa aattatggat
      301 ttatgatcag cgagaaacaa aaagtccatg gatcttaacg ataaaattat ctcagccttt
      361 cacaaccgat gcaggatttt ctatgcagga tgtcctatat ttcaagaaag ctgaggagta
      421 tcaattagtg aatgaagaag aactggaaat tgtcagagga caaaattcaa cgaatgtgca
      481 aacagattat tcagaatatt taaataatgg tcgggcgttt aaacttgtct taaccaaaga
      541 aaatcagata gctggtaatt actcagcaga gatgacatgg acattagcag atgcgccgac
      601 agaataaaga tcaaggagaa tgattgatga atcgaatatg gaataaaagt catcgaaaca
      661 actgctcttt acttctgatc cttctccttg gattcatcct ttggcagaca cctgtccatg
      721 cctccgaatt caattttgcg gtagattttg aattaccggc taatcagatt gataagaaca
      781 aaacatatat aaatgtaagg atggagcctg ggaaaacaca ggaaatcccc tacacggtct
      841 ttaaccgaac agataaatca gtaacagttg agacattgat ccactccgct acgacgaatt
      901 caaacggtgt gatcgaatat ggagaatcaa aaagtaaatt tgatgaaaca ttaagttatg
      961 atatgaaaaa cttagcaaaa acagtgggag aaataactgt ccctcctcaa agtgcggtca
     1021 ctgagacact ttcactgaaa gctccagaaa aagagctggc tggtgtggtc gcaggaggaa
     1081 tcacgtttca agaaaaaaaa gagaacgttt ctaacaaaag tacagttggt gtcgtcaatc
     1141 agttttctca agtgaaagca atcttgattc gaaatagcga aaaagagtct tccccaaatt
     1201 tgaaattaaa aaaaacttat gcggatcaaa gcgatggaag aaatgtgatt aaggcgaatc
     1261 ttcaaaatcc aaatgcttct tatatgttcg gcttgactac atcggttgaa atctacaaaa
     1321 aagaaacaaa agagccttat ctttcaataa aaaaagaaaa aatagatgta gcacccaata
     1381 caaattttga tttacttgtc ccattagaag gaaaaaaatt agctccggga cattatcaag
     1441 cggttgtgaa gggtgcttgg aaagaaaaac gctggaatct ccataccgat tttgaaataa
     1501 ctgatgatgc agcggaccaa ttgaatgaaa aggatattga tttaaaaaat cagccagaaa
     1561 catttgactg gcgatggctg atacttgttg gagtcattct tattggctta tttgctggat
     1621 tatttatttt aaaagaaaga aggaaaaaga aatgaaaaaa acaattgcat taagtaccgt
     1681 tctagctgga agtctattat tatgtacaca aagtgttttt gctgagaata agagctcagc
     1741 cactacagaa ggaacgattt ctgtaacaaa accagatgcc gcaaatcctg aagacgttgt
     1801 tccagttcct cctgttgatc caaatgatcc cgatacgccg tttacaccta acgaaccaaa
     1861 tcagggaaca tccggattac tgacgattga ccaagctcca gatcttgatt ttggaacaat
     1921 caagttaggt acagcaaaaa cagtatatgc tgcattacaa aacggaacgg acagtacagg
     1981 gacagcaaca caagtacaga atttcgtaca agtaacggat aaaagcggaa tttatgccgg
     2041 ttggaaacta tcagtcaaac gaacagaatt tattggtaca acatctgata cgaataaact
     2101 aactggttca aaggtgaaat tcaaaaacgc cgtgattcga aatagcgcaa ctaatagcag
     2161 tggaacgcca tctactattt ctggtactgg cgctgaagga attgagatcc cagcagatca
     2221 ggcagtagat ctagtaactg caggagcaaa tgaagggatt ggcacatgga tttattcatt
     2281 aggagagaat gtggaacaag ggagacaatc agtggaatta tttgttcctg tatccaatta
     2341 tgccgtagac aactacgttt caacattcac atggtcgtta acagatgctc ctacagaagg
     2401 gaaagcgtaa aatcaaatca atgacttcag ggagtggagc cgattcaagg ccaactccct
     2461 gaaatctgct atgcttacgt ctcagctctt attcatcaac tcgaagcagt tttttggaag
     2521 tcatggaaac gttcctttgt cttttcaaag atctttcgac caacgagtaa ggagtcacca
     2581 ttgaaaaatt ctaacacata atgagcagaa tcaattttct gcaattgcga taagttgata
     2641 cagtaagatt ttaatagtaa aaagtaagca tacttttcca actctgtctt caattgtttt
     2701 aaagaagtat tcactaattt atcttctgta gttgttttga ccataacttg gtttttcaaa
     2761 cctttgatac tttcaatata taaaatttcc cgaggataca ggacgagact tccacctttt
     2821 tgatcaataa agattttatc gacatttacg atttgctgtt ctttccaatt gatctgttct
     2881 agcacttgac gaatttgttc agataaattc ctgtcttttc tgatatatcc aatcggaagg
     2941 attttccgat tgatgatctc tactgcaaaa ttcgtataag cggtgaaaaa aacaatatta
     3001 ctatgtgcat tttttttacg tatttgttcg gcgacatcaa tacctgtgag tgattgcttc
     3061 aagtcgatat cgataaagaa aacatcgtga ttatcaatag tacccaactg gatcaactga
     3121 ttgatttgag agatagaagt gagctgcacg atattctcga tatgatgatt gaccaattct
     3181 ttgatgatcc attcgctgtg aaactggtta tcttctatga taaaatactt tttcatatgc
     3241 aggctcctat taaaaaaata tgtgtacatt ttgaaacaaa acaatggagg aataagatgg
     3301 tcgcaacagt gacactttat ttgaccttta ctttgatttt agatttaggt atctatttat
     3361 tcttttcgaa acaactgcta gtaaaaaaca gctttggttt tatagctttg atggtggtga
     3421 cacttttatt tcctatccct aaagtgagct ttccttacct agttggctta ttattgatgt
     3481 ttctttttta ttttactacg aaaaacctgt ttatcagctg tttgatcagt aatctttttt
     3541 ttgctatcac tggactcagc ttttttctgg tttttgatct gatggattat ttaggaaaga
     3601 gacatcttgg aacagcaagt ttttttgcac tacttatcgc atttattttc tatctattag
     3661 taaaaagtat agacaaacag acgagatttc tcaacttgct ttttacttat ccaactgaac
     3721 actattttgg aggtatttgt attttattaa gctggggcgt gatttacttg gtattgggaa
     3781 gtgttcactt ccgctcatct aattatctgc ttctatctct tttgtcgata gtcatcagtt
     3841 ttttttcttt gtttttttcc attatgttga tcagtttcca agtaaaagaa agacaacatc
     3901 aggaatcgct tcaactgtat caaataaatg aagaatatta ccatcatcta gaggaattca
     3961 aacatgatta taaaagtcta ctgttttcat taaaaattac tcttcaggaa aataaaaaag
     4021 aaacgttgga atttttagaa atcttagaag atcattctgc agctattttt gaaaaaccgc
     4081 aaatacaaca gctaacaaat attgtatccc cagctgtcag gggtgtcttt ttaaaatttc
     4141 tagaaaaagc agaatcggag aaaatcccga tccaagtagt tattcctgtc gaagtgaaaa
     4201 caatcccgat tgatctggtt gtttttattc gctgtttatc tatttttatt tctaacgcat
     4261 tcgatcatcg tgtagccgat cagagtccga ttacgatcaa tctgctggaa gaaaaagagg
     4321 gattacgttt tagtatagcg aacaaggcaa atccgacgaa tttgacgcta tcggagatgg
     4381 tcaaaagagg aaaaacctct aaaaaaaatg gcgggttagg tctatacagt gcgaaaaaaa
     4441 tgttggatgt ttacgaaaat gcagaactaa aaatcgaatt ttcaaaacag aatcactatt
     4501 tttttgtaga aatgtatctg gcatctagaa agagcaaatc agcctactga cttactgtca
     4561 aaggataagc ttgaggaaag tctacacgga gatagagaca acaacacagc atattcaaaa
     4621 gaaacagaag cgtgatgacc gttgtcaccc ttctgtttct tttgctatgt agttaaacaa
     4681 agtagttgac acttccgcta cttagtatta gtacgaaagt atacttcatg atactaagta
     4741 gataagaagt gaaaagcgga acccacgatc gtcaaaatgc taactgcttt gcttacacca
     4801 gataaaggga agagcaatat cgcttatttt aggcgtggag aagcaagaaa atccctacga
     4861 tcacacaaaa aatgctgacc cagcagttaa gagagttaga acaagatggc attgtccatc
     4921 gaaaagtcta taaccaagtc ccgcctaaag tagagtactc gctcaccgaa gaaggaaaat
     4981 cattaagaga gattctagta gcgatgtctg tttggggaga agaacgtatc gaaaaacaaa
     5041 aagcctcagg ggaagaagtc acattactgc atacacatgg tggctaccta aattactgat
     5101 ttctatgaca tttattttaa ataaaagaaa acaggagttt ttttaaaagc atcatctatt
     5161 ttttatgtaa aaaaatggta tgattaatca agtaagaaat gattggaaga aggcaagcaa
     5221 atgaatagca tggaaaaagt taaccagttt agagatgaac gtaattggcg acaatttcat
     5281 aacgaaaaag atttggctat ttctatttct ttggaagcat ctgaattgtt agaacttttt
     5341 caatggaaaa cgccggaaga agtaaaagaa acacaattag aacgaatcaa agaagaactg
     5401 gcggatgtat tgatctattc atacatgatg gcagacaacc ttcagctgga tctagatgag
     5461 atcattgaag aaaaattgat caaaaataat ttgaaatatc ctgtagaaaa aagcgcaggt
     5521 gtacgaaaaa aatacacaga gttttagaaa tgtgtcattc ggctgttgga aagagcaaaa
     5581 gaaaaacagt aaaatgagtc tggagggaga gaaaatgaaa aaaaaaggaa aagcaaaaag
     5641 atggctagtc aatatcctct tgttcctctt gttattagta ggactagctt tgattttcaa
     5701 tgaacagatc aaggattatc ttgtcagaga gacaggagat aaatatgcta tagcgaatgt
     5761 aacaaaagaa gatctgaaaa agaataacga taaagatgtc agttttgact ttgatgcggt
     5821 agaaccaatg acgacagaag gggtcatgag gtcgcagatg agaggaacag atctaccagt
     5881 gattgctagt atcgcagtcc cttcagtttc aatcaattta ccgattttca aaggcttgga
     5941 taatacgtca ctactttacg gagcaggaac attatctcca gatcaagaaa tgggaaaagg
     6001 aaattatgcc ttagcaagcc atcgtgcaac gaaccctgaa ttgttgttta caccgctgga
     6061 aaatttagag atgggtgcca agatctattt gacagattta gaaaatgtgt atacatacaa
     6121 aacatttttt aaagaaaaag ttgctcctac agatacccaa ttactgaatg aagtcgagga
     6181 aaaagaaatt gtcacactaa ttacttgtgg cgacatggac gccgtcacgc gactagttgt
     6241 acaaggagaa ctggaaagtg ttacaccgat aaaagatgcg acagatgata tgagatctgc
     6301 tttcaatcta gagacaaaaa cattttagga tactgggaca taagtcgtta cagattaaaa
     6361 acagccaaag gatatgaatc gataaggaaa aaccaatttg ctgaaaaaaa gaggaacgca
     6421 aagaggtgca tctctgattt ggttgttttc tagatagact tgtgttccag tttttttatt
     6481 ttttatatga aaaggcttgc ataaataaaa attcgatggt atgatgattt tgaataagaa
     6541 atggattgtt actgtacggc aggcaaaacc agaattcagc taagaaacag taggcgaatt
     6601 ctaggttttt ttatttttct tgagagggcg aagcaaaatg aaaattgata aaattttgaa
     6661 taacaatgtc gtcatttcga aaaatggatt cggggaagaa gtcgtttgta tgggaaaagg
     6721 actagctttt caaaaaaaag attggggacg agatttcgcc agaagcggtc caaaaagaat
     6781 ttattttaag agattctttt gctaaaaacc aattccagca gctgatggct gatattccgg
     6841 cagaggagat cgaatgggtc aaacaagtag tcgaactggc tgaagataaa ctaaaagttg
     6901 aattttcgcc taatatttat ctgacattga ccgatcatct tcattatgcg atcacacgag
     6961 caaaagaaaa tatccaactg cctaatccat tattatttga aacaaaaaaa ttttatccga
     7021 aagaatatca agcagcgaaa gaggctcttt tgttcgtgaa acaaaagacg ggtgtggaac
     7081 tttctgagga tgaagccggt tttattgcct ttcattttgt gaatagccaa caaggaaacg
     7141 aagacatgca agtgacgatg accgctacca caatggtaag agatatactg agtatcatca
     7201 gtaaattctt cggcatcgtg ttcgatgaag aatctttgaa ttatcagcgt atcattactc
     7261 atctgcagtt ttttgcccag cgttatctca aaggggaagg atctgacgag caagatgaat
     7321 ttctctacgc attagttcaa ggaaagtatc caaaagcgtt tcattgtgtc gaacggatca
     7381 atgagtatct tcgacaaacg caaaaacagg aaatggggat cgcagagcag atttatttaa
     7441 cgattcatat tcaaagagta gtaagtgaga aaaaaagcat ccaatcataa ggattgttac
     7501 tgtatggcag gcaaaacctg gattgaaaaa ataggttcac gaatgtttgt gactgttttt
     7561 ttcaatctgg gtttttattt tttaaataaa aaagaaagaa ggaaaaaaca atggataatc
     7621 aagcagttgg tcgtcgtgta tgggaagcgg taggaggaca aaagaatgtc aaaagtttag
     7681 tacattgtgc tacgcggttg cgattcagat taaaagatga atctttagca gatacgcaaa
     7741 agttaaaaga agacccggac gtgatccaag tcgtacaaag tggcggtcag tatcaagtag
     7801 tgattggcag taatgtagca gatgtttatc aatcgatcgt ggatgaggaa ggtcttgcag
     7861 tttcggagga tggaaaagaa gagtccaaaa atattttgaa tcgtctgatc gatattatct
     7921 ctagtatatt tacacctttt ctaggggcga tggcagccgc cggggtattg aaaggattct
     7981 tatcattggc aacggtgatg ggctggctga cagctgatag cggtacttat caaatattgt
     8041 ttgctgcagc agatggtgtc tttaccttct tacctgtcat gcttgctttt acagcagcta
     8101 aaaagttcaa agccaaccag tttttagcag tagcaattgc tatggcactt gtgtatccag
     8161 ctatcacagc agttgctggt gcgggagaag ctatcagttt ctttgggatc ccagtgattc
     8221 tttcaccatc tggttatact tcttctgtca taccaatcat tctagccgta tgggttcaaa
     8281 gtaaattaga gccattcgta aaaaaagtga ttccgcaatt tctgcaaatg attttagttc
     8341 cgcttgtcgt tttagtagtg atggttccat taacatttct tgctttagga ccaatcggga
     8401 cggttgccgg taatgcttta ggcggtctct tcaactcgat ttatggattt agtccaatcg
     8461 tagcaggtct aatcatggga agtttatggc aagtattcgt gatgttcggc atgcattggg
     8521 gattcgtacc gatcatgttt ttgaatatcg aacaatatgg gtttgatgta ttgatgccaa
     8581 tgcttcttcc agccatcttg gcacaaggtg gggctgcttt agctgtagca ttgcgaacaa
     8641 aagatacgaa acttcgagca ttagggattt cttctacagt gacttcgtta tttggaatca
     8701 ctgaaccaac tgtgtatggt gtgacattac ctttgaagaa accattcatt gccgcttgta
     8761 tttctggagg tattggtgga gctattatcg gattttccgg agtaaaagct ttctccagca
     8821 gtttggtcag cttattgacg attccgactt tcattaatac ggtggatggt gtagagtcaa
     8881 atgtgacagt agcagtaata gctacaggaa ttgcttttgt tcttgcattc gtaggtacat
     8941 tgattttagg atttgacgaa caaacacaag acaatcaatt agaaaacaaa catgcgaatg
     9001 caggagaacc gattacttca gcacggcata ccttaaaaag tcctttaacg ggtaaagtac
     9061 tgccattgag tgaagtacca gaccaagttt tttcttctgg cgtgatggga aaaggtatcg
     9121 ctattgatcc agaagtagga gaactagttg cacctgcaga cggagagatc acgactattt
     9181 ttccaactgg acatgctgta gggatcacaa cgactgacgg agcggagatt ttgattcata
     9241 tcgggatgga tacagtagaa ttaaatggga atggctttga gatcttagtc aaacaagggg
     9301 atctcgtcaa agcaggagat ttattgattc gttttgacat cgaagcaatt agagcagctg
     9361 gctatagcgt aatcactcca gttgtcatta cgaatactga tgcatttgcc gatatacttg
     9421 aattagacca aaaagagatt attgcaaacg aagatgttct ggcaattgta aaataaggag
     9481 gaaatcagga tgcaatcacg tttttcagaa aaatttttat ggggtggagc aactgctgcc
     9541 aaatcaatta gaaggggctt atgatcgaga cggaaaagga ctatccgttg cagatgctat
     9601 gcctggaggt aagcagcgct ttgcgattat cggcagtgaa gaatttgact ggacgattga
     9661 tcaagaaaaa tatatttacc cgaatcatcg aggaatcgat cattacgatc gtttcaaaga
     9721 agatcttgcc ttgtttgcgg aaatgggatt caaatgttat cgtttttcga ttgcctggac
     9781 acgaattttt ccaaatggag acgaaggtac tcctaacgaa gcgggattag aattttatga
     9841 tcagctgatt gatgagtgct taaaatatga tattgaacct gtgatcacga tttctcatta
     9901 cgaaatgcct cttcatttgg caaaagaata cggtggctgg aaaaatcgaa aactgatcga
     9961 cttctatgaa cgatttgctc agacagtatt agagagatac agcagtaaag tcaaatattg
    10021 gatgactttc aatgaaatca attcggcctt tcactttcca gctttaagtc aaggattagt
    10081 aaaaagcaat ggagcaggag agtaccaaaa tattttccaa gcatggcata atcaattcgt
    10141 tgcaagtagc aaagccgtaa aaatcggcca cgaattgcgt tcggatatcc aaatcggctg
    10201 catgattatc tatgcaacaa cttacagcat cgatgccaat ccagtcaatc aggcagcaac
    10261 aatgatccaa aaccaagaat tcaatttttt ctgcacggat gtccaagtac gtggagaata
    10321 ccctgcatac acagcgcgta cccataaaaa atatggagtc gatccggaaa aattagagca
    10381 aacggaaaaa gacttccagt tgctaaaaga atatccagtg gactacatcg gatttagtta
    10441 ttatatgtct acggcaatca atgagactga tccacaagca gcaacttcag aagggaactt
    10501 gctgggagga gtaaaaaatc cgtttcttga ggcaagtgaa tggggctggc agatcgatcc
    10561 agaagggctg agaatcgcat tgaatgaatt atacaatcgt taccagaaac cattattcat
    10621 tgttgaaaac ggtcttggag ccattgatca tatggaagag gatggcacga ttattgatga
    10681 ttatcggatc gattatttac gtcgtcatat cgaagcgatg gctaatgcag tagcagacgg
    10741 tgtagatttg atgggctata cgccttgggg atgtatcgat cttgtcagtg catcaacagg
    10801 agaaatgagt aaacgttacg gctttatcta tgtggatcta gacgatgaag gaaatgggac
    10861 actgaatcga tcaaagaaaa aatcttttga ttggtataaa gaagtaattg cctcaaatgg
    10921 cgtaaacttg taattaaagc agctgaatga aaaagaacac acttctcaca tgtgatttgt
    10981 gttctttttt tattttttat gtgctattct tttagtaata gtaaagcaaa gggtgacgtt
    11041 atgaaaagga cacgtgtact atacttggaa gtcgcagata aaattaaaga agatattttc
    11101 tcaggaaaat atccagtcgg ttcgatgttg ccgacagaaa gtgaattaga agaactgttt
    11161 caagtcagca aaatcactgt ccgaaaggca atcgaactgc tggcatcaga tgaatatgtc
    11221 gcaaagaaaa gtggtcgtgg gacgacggtt ctaagcaatc gtccttacaa tcgattatcc
    11281 aaagcggcaa gctttacgca aatcttggag aactcccgat atgaagtccg gaaagaaacg
    11341 ctggatttgc aattggtcca tataaagaag gaagatcctt tgttttcctt tttcggtgag
    11401 caagctgttt gttttaagcg cttatattat ttgaacaatc agccttatat ttattttgtt
    11461 cattatcttc cacaagaaat gatgcaattc agcagagaag aatttggcaa agaatctttg
    11521 tatcgtttgc tgacgaaaaa aggatatact attgactcat tttctgatga tttctcggca
    11581 gtatttttaa cagaagaaga acaaggaatt ctgaaaacag acgcacagat cggcatcaaa
    11641 cggatacgga aatcgtctac gcaaattggg gaaatgattg aatattcgga ggcggtctac
    11701 catacggagc tgcatcctta ccatattgat tatgaaacat aaataaaaaa agaggttgtg
    11761 aaaaagctgc cctgcatcaa gtaataagaa cagccaaaca aaaatagctt ctcatatttt
    11821 tcgtttggtt aggcttatta ccgcagatac acggctgttt ctggattacc atttattctg
    11881 gataaggggg tgtggcacga ttttcagaag gaatctatga accaatcact gtattgattt
    11941 tagcttcgat ggtaacccca ttcggcttga cgatcgctta tttcttaggg aaaatcattc
    12001 gtaaaaatat actcaatcgt caagaaatcg atacattgaa gaccgctttt cctatgggga
    12061 tctgtcagat cacagaggga tgtttcccta tcgtattgaa cgacttggca cgcaatgtca
    12121 tagcaacggg agtcggtggg acagtaggtg gcggattaag catgttttgg ggcgcagata
    12181 gccgtattcc ggcatcggga atgtttgcag tcgctacgat gaccagacca tgggcattca
    12241 ttggtgcatt gttagctggt tcttttgtca caggaataac cattttatta ttgaaaaaac
    12301 cagtagatcc gaatgcagaa atcatccaag aagaaaaaga ggaagaagac atatcttggg
    12361 atgatttgac aattagttag gagaggcaga atggattaca agaaaaaagt acaatagatg
    12421 taccttgaga caggaatggt atgaaagaat cagagttaga aagaatcgaa tatacagatt
    12481 ttggtttagg agcgatcgaa actgtccaga gcatcggcac cctccttgaa atgacgatga
    12541 aggaaaaatg agaacctttc gttgtcgaaa gggtctggta taccttatgt cgaaggaaag
    12601 gaaacaaaaa aactttcctg tactattcca aaaaggaaag aaagttatta tacagtaaaa
    12661 aaagaaatta ttcttcatgc tagagatcag tacacgttcg agcccaatat caaacactag
    12721 ttccaggcag gcgcaacagg tgcggttatc actgaatttt cttccagcag tgacgattca
    12781 agtgatattt ttacaaatcc agctatttat cgttaacaaa aagattttta ggagaagctg
    12841 atgaacaaaa atgatcaaat tttgatcgtt tagttcgtcg gcttttttat ttagagaaac
    12901 atcatttatc agtgaaacat aacacgagaa caaaatgatt ttttcgttaa taaaagaaac
    12961 aagtatttgt tgtttaaaat aatacacgtt attggcatat aggacgaaat cccagtatct
    13021 tctataagta agtcatttca tatcgatgaa aacacgttat ttatttttgt tttatctata
    13081 aaatggctga aaaatgattt ttttctaaat actatatata gtggcgtcta tcctatatac
    13141 cactaaaaaa ctacaaaatc tagtctttta ttttaaaaaa acacgtgtag aatgaagata
    13201 gacttttgag ttagggagtg tttttttatg aaacttactg ttttttgcgg ttcccgtttt
    13261 ggtaataaag aaagttacaa atttattgcg caaacgttag gaaaatacat ggcacaagaa
    13321 gaaatcgaac tggtttacgg tggttcatac tccgggatta tgggagtgat tagtaaaaca
    13381 gtactggaaa ataacggaaa agtcacaggt atctatccga atgggctttt tgaaactgaa
    13441 ttgcctggaa aagatgttac tacatttatt cctacagaaa cgatcgatga aagaaaggta
    13501 ttattatttg aaaagggaga tgctgtcctc gttttccctg gaggtctagg tacattggag
    13561 gaattctcac aacttctttc ttggatagca atcggtctga cgcccgacaa gccaatcgga
    13621 atattgaata ttggcggtta ttacagcggc ttgcaacaat tattagaaac ttttgcaaaa
    13681 gaggatttta tggataaaaa atggttggat caagtaatct tttccaacaa tccattggaa
    13741 ctggtcaatg aattacgagc agtatctatt aaaaatcagt tattattgaa ggaggcaaaa
    13801 taatgagtca aatatattta gcaggaccat ttttttcaga ggagcaaatc gatcgagtaa
    13861 gtcgtatcga aaaagcgttg gaggaaaaca aaacagtcac aagtttctac tctccacgtc
    13921 atcaccaaga aagcaattat gaactattca gcgctggatg ggcgcaggaa gtatacgaaa
    13981 aagatatgga agaactgaca aatgcagaat ttgttgttgc tatccttgac tttgagcatc
    14041 aaacaatcga tccaggaacg gcttacgaat taggtgtggc aactatgttg aaaaaaccga
    14101 tgatcattgt acaagaagag acggtaccta cgaacttgat gattacacaa agtctccata
    14161 cgtatttaaa atcagaccaa gctgtacgtg aatatgattt tgaaacattg cctgttgaaa
    14221 cttacgtagg cgagtactta tagaagagga agggttgtat gtcagtgatt ttgatttcag
    14281 gaacgattgg tgcaggtaag agcagtttga cggatatgct tgcaaaagag attgattcta
    14341 aaccatttta tgaaaatgtc gaagataacg aagtattgcc gctcttttat tcaaatcctg
    14401 agcagtacgc ttttttattg caaatcttct ttttgaacaa gcgattttta gcaatgaaaa
    14461 atgctttagt gaacgatgac aatgtgctag accgatccat ctatgaagat agcctgttgt
    14521 tccatctaaa cgctgattta ggtcgggtaa cggatatcga agtacagcag tacgatagct
    14581 tattagatac gatgctaaac gagttagatg atgttgctcc aaaaaaacgg cctgatttga
    14641 tggtccatat caaagtttct ttggacacga tgctagaacg tatcaaaaaa cgtgggcgtg
    14701 actatgaaca gctagaaagc gatgagacgt tatataccta ttatgaaacg ttgaacaccc
    14761 gctataatca atggtatgaa gattttgatg tatgtcctaa aatacaagtg gatggggata
    14821 aattcgattt tgtagaaaat ccagaagatg caaaaaaggt gatccgtcag atccaagaaa
    14881 aattagctga attggaagga aagcctgctg gaaaatattt tacggataac cagcatgcaa
    14941 aaggtcaaga attaggctaa aaataaaaaa ccaaacgacg ggaaagaaaa att
//
LOCUS       DAMEEU010000068        14759 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.069, whole genome shotgun sequence.
ACCESSION   DAMEEU010000068 DAMEEU010000000
VERSION     DAMEEU010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.069"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..2131)
                     /locus_tag="PB779_002172"
     CDS             complement(<1..2131)
                     /locus_tag="PB779_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0739684.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWM"
     gene            complement(2128..2832)
                     /locus_tag="PB779_002173"
     CDS             complement(2128..2832)
                     /locus_tag="PB779_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0739685.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            complement(2844..5153)
                     /locus_tag="PB779_002174"
     CDS             complement(2844..5153)
                     /locus_tag="PB779_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HDE0739686.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            complement(5348..5812)
                     /locus_tag="PB779_002175"
     CDS             complement(5348..5812)
                     /locus_tag="PB779_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739687.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            complement(5812..6438)
                     /locus_tag="PB779_002176"
     CDS             complement(5812..6438)
                     /locus_tag="PB779_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HDE0739688.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            complement(6445..6810)
                     /locus_tag="PB779_002177"
     CDS             complement(6445..6810)
                     /locus_tag="PB779_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HDE0739689.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            complement(6800..7138)
                     /locus_tag="PB779_002178"
     CDS             complement(6800..7138)
                     /locus_tag="PB779_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739690.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            complement(7128..7454)
                     /locus_tag="PB779_002179"
     CDS             complement(7128..7454)
                     /locus_tag="PB779_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HDE0739691.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            complement(7435..7713)
                     /locus_tag="PB779_002180"
     CDS             complement(7435..7713)
                     /locus_tag="PB779_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HDE0739692.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETD"
     gene            complement(7715..9079)
                     /locus_tag="PB779_002181"
     CDS             complement(7715..9079)
                     /locus_tag="PB779_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HDE0739693.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            complement(9092..9661)
                     /locus_tag="PB779_002182"
     CDS             complement(9092..9661)
                     /locus_tag="PB779_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HDE0739694.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            complement(9633..10820)
                     /locus_tag="PB779_002183"
     CDS             complement(9633..10820)
                     /locus_tag="PB779_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HDE0739695.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            complement(10884..12611)
                     /locus_tag="PB779_002184"
     CDS             complement(10884..12611)
                     /locus_tag="PB779_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HDE0739696.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            complement(12608..13060)
                     /locus_tag="PB779_002185"
     CDS             complement(12608..13060)
                     /locus_tag="PB779_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HDE0739697.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            complement(13172..13552)
                     /locus_tag="PB779_002186"
     CDS             complement(13172..13552)
                     /locus_tag="PB779_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HDE0739698.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            complement(13549..13935)
                     /locus_tag="PB779_002187"
     CDS             complement(13549..13935)
                     /locus_tag="PB779_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739699.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            complement(13937..14215)
                     /locus_tag="PB779_002188"
     CDS             complement(13937..14215)
                     /locus_tag="PB779_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739700.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            14263..>14759
                     /locus_tag="PB779_002189"
     CDS             14263..>14759
                     /locus_tag="PB779_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739701.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLG"
BASE COUNT         4127 a         3154 c         2319 g         5159 t
ORIGIN      
        1 ccatccattg tccatttgta aatgtccaaa taagcaatcg aacttgtgca tctaagctcg
       61 ttattggttc tttaatacct gcagcattaa ataagttttg aacataaact tttccatccc
      121 atgttgctgg accaacaaga ggatatgaag aaccatccca ctgaactaat ccgtatgctg
      181 gtccacctat ttgaacagta tcaggatcaa aagttcctcc tgtttcttgt tgaatgttcc
      241 ccaatattcc acatgcagat tgtttcgtaa atccgttatt acacaaaata tcgtatattc
      301 tccaagctct cttttctgca tctgttttta attcatcagg atacccacca ggtgtttctc
      361 ctccgccaga tggaccgcca ttttgtcctg gtatcacttc tttacctcta acagtaagtt
      421 ttccctgaat atctaaatca ccgaaataat atgcttttcc gtttcctaat aacacaaatc
      481 ctttttctgc agttggagaa attaaaatgt attttccatc gccatttgta cgtattacca
      541 aagaattttc ctcaagaggt gtaggtgtta cagcatttgg aaatggattt cctgctgaat
      601 ctgttgttcc gatcgttcca atggattctt ttctattcca gaattccata ccttttttgg
      661 ttagctccat gatttttttg ttttcattcc aaatttgaag cgtgcctttt acaagtttta
      721 acacatcacc ataagcatta aaggaagttt cgaatacttc tgcatttatt gttcctactt
      781 tgatgaagtc agcaacaatt tctccttttg atgtgatagc aataccgaac gggccattta
      841 ctccgttgtc tgaataacct aagccattta aattccaacg ccacactcgc tttgcattcg
      901 ccacatttgg agtatccatg ataagaatct ctgatggagc tttttctgga cgaaaaacga
      961 catgcccacc agaattacca gtgatccatg ccgtcgcatt caacacattt tgaactaacg
     1021 tttctgttcg attgtcgatt ttctttttca attcttgtgc ttgagtattt actgccgaag
     1081 tgtacagtga taaatcatta cctaaaacaa tatccttata tttcccaagc gttgggaaat
     1141 aagtgtattc gaccatacgc tcttttatct cgatatctag ctctttcgcc ctaacatgag
     1201 cgacatcacc aaagtgtaaa gacgctagct cttgatacat gtcaccgtat tcgagtgtgt
     1261 gttccaacgc caccatactg actgtatgag tagcttttgg ctcatggata cgatcattgt
     1321 caaataaggt tttgccccat ttgatcaatt catcaactgt tttacaatct ccgttttcac
     1381 gtttggcaat acgtcgattc tcgttggtta ctccatcaat ttctaaataa ccatattcga
     1441 taggttcttt gtcttcatca taatcgttat caggaacacc gccaaccaaa tacaaactat
     1501 tgacaattga ttcttcatca atttcttctt cgattgcttc taaattgatg ccaaaatcaa
     1561 tccgaaaacc attatctgat ccaatctgtt ttaccagttt caaatcatag ttatccatat
     1621 caagttccgc gctagtcacg ccagtcaaat tttgattacc gttatttgaa ccaatgattg
     1681 cttcaactgg cgcgacttgt cttgctgtaa attggtgcgt tgtccctaca ttcgaaagat
     1741 agttaaattt ttgatcaaat gccaaactgt ttttaagatt ggtcatgatc tgagacccat
     1801 tgccgttatc cgtaaacgac ttgacaataa agttcttatt ggccataaaa ccaatatgcc
     1861 gagctgttac agaaacggag gtcaaattct ttttgacatt ataaatttca aaatattgcc
     1921 atgatccatc tggtaccttc gcttttataa aatttccttt ttttaaataa gagcgatact
     1981 gtccgcttct tgaatagtta ccataaaaac gatattggcc attcagcaca cgattgattt
     2041 ctggcaaatc ttcccaatca actaacgacg ctccgttcac gctcaaatca tctggcattt
     2101 ttttataagc ataaataaat tcttgcgtca cagatacaca ctcctattcc aaaaccgcac
     2161 ttctttaaat tttccggata tttttacctg attccattca ggctgcaata ctggccaatc
     2221 accacgcgta aataaattca aaccttcttg tattgctttt ccaagctgag tatcaaccac
     2281 gattgttgca gctaacgtat taagtattgt taggctttta tcaccgacag cgatcgttat
     2341 atctcctccg ttcgattcta tttccagata gggatgtgca atttcgtcac catgatcaaa
     2401 aatatccata acactagaat gaaaaatttt aggtgcttca ccgatttttc ttttgagtgg
     2461 ctgacaacga aaagtaacat cgaatgtata aaagaagccc cactcgtttt cgaaagggac
     2521 ttctttatcc atgctgcaga tagcctctag atacttgtct ggatcattat gtgtgattaa
     2581 ttggctttta ccagtgagcc atcgtttgac ttctctcagt ttcgaatgtg gaatagtgat
     2641 cccttctatt tccaaatcaa aaggttcata gtcatcaaac gtctccgtca attctccgct
     2701 tcggccctga atcgtgtaag tttcgtatcg cttgttcggc ataatatctg gaagctctgc
     2761 ctcaatgatg caattcatat caattactgc attccgattt ttccaaataa aatttggttc
     2821 atctggattc ataaattgtc gactcaaata ggaacacctc ccaaatcacg aatagcctgt
     2881 ttgtttgctt tagcaaattt acgattcata cgatctaact cagatggatt gtttgcatcg
     2941 actttgccaa tgtgtatatg ctgttcaatg ctacctccag aaactcttcc actgatccct
     3001 ttgcgttttt cttcgtctga taatggagta actgtggttt taccattctt ggcagtcagt
     3061 aactcaggtc cagcttcacc aacaatcgct tgtccattga ttagatgacc gccttgtgct
     3121 aaataaggca gttttgaaat agaaaatgat tttccaccta caccaggaac ccattttggt
     3181 atctttatat tattcaatcc accaataaat ccattgatca atccaatcat ggcattaata
     3241 ggagctttcc ctacagcaac aataccatcg aaaatacctc caaaaatatc aactagacct
     3301 tgccatgctt ttgaccaatt ccctgtaaat actccagtga taaaatctag aaaaccactg
     3361 aaaattcgtt ttccagcatt ataaaaatta ttgaaatttg ctataacacc atcgaaaaat
     3421 ccaccaaaat aaccacttaa aaaattaaat atttcaacag ctacatctga aacacctttg
     3481 aagaaagaat tcactccatc atgaaaccat ttaacgttat tatatgccca aattagtcca
     3541 gtaactaatg cgccaatagc tataactgct aatgcaaacc agcctcccga cattccaaat
     3601 aaaccagcaa gtccttgcca aactcctata aaacttttaa cttccccaac gatttttgta
     3661 acagatccca taagtgaacc aagaacgatt agtactggtc caactgctgc cgctatacca
     3721 gcaattgtta tgatccaatt ctttgtatct tgatctagag acccccacca tttagagaat
     3781 tcctgtaata aggaagttgc tttttcaaaa aaaggcaaaa ggcttacttg gactgcttca
     3841 cctacgtcag ccattgctaa ttttgcattg ttcatagctt gatcggcttg atcaattggg
     3901 tcgagagtag catcgaatgt gtctcctaca gctcccccac tttctccagc agtttttgct
     3961 aaatcttcca ggttcaaagt acctctacga attgcatcgg ccattctagg accgccttta
     4021 gtcccgaata cttctgctgc tgcattgatg gcttctgttt cagaacctgc attttttacc
     4081 ttgtcttgta gttcttctag tccttgactt aaagattttc cgtctttcgc ataagccact
     4141 gttgctttag ataaactact taaagctgcg cttgaatcaa caccagattg ctcaaattgt
     4201 ccaagtaaag tgaccccttc accaaagctc aaccctaatt gtttaatttg tggtgcgcca
     4261 tcaattgctt tttgcatcaa gtcgtctaca gattgaccag tattctgcga tgttttcgtt
     4321 gttacatcaa ggacagaatt caaatcatca tattctagtc cataagcatc aatagcttgt
     4381 cgagcagata ttgctgattg cgaaacatct gtatcattga tttcagcgta ctgtaggaga
     4441 taattggttg aatcttccag ttttttatcc atgaatccaa attgtgtatt tacctcacca
     4501 atagcttccc caaccgtttg taaaggtaaa tgagtatttg aaccaacgtt tttgaaagac
     4561 tgtgaaagtc tatcagcttg atcacctgtt gctccggttt ttgtaatgat ggtatcaagt
     4621 gcctcgtcaa cttcaccaaa tgctgcaagt cctgctgctc ctgccgctac aataggcgcg
     4681 gttactccaa cagacatttt ttcaccaacg ccttttactt tctcacctgt ttcttcgatt
     4741 ttctggagtt tttttgctgt atcaacagaa acgtcacctt gttctttaag tgcatcgttc
     4801 gtctgttcta atgctgtacg aagtttattt tctccggttt cagaattgag taattgttta
     4861 taaagttttt ctgattcagc agaatattca ccggtttctt tgacagattt ttcatattcc
     4921 tctctcagca tttgagatcg ttgttcagcc aatcctaatt gtttttctaa tttttgttta
     4981 gccgctcgca atttttctgt ttgagttgca tccttgtcca tcgcagacac ttggtttttg
     5041 tactcggcag cggctaagtt catttctttg ttgatttctt tgattgtttt cgaataactg
     5101 acttcgccat tcgttttaaa attaagaacg acatcagatt ctttaccagc catttatctt
     5161 agcgctcctt tctaccacca aggcgattta tccatagtta cagattgagg tggttcaaaa
     5221 tcggtgtttt gttgtaacca ctgtaaataa gatttgagcc acaagttagg tgtagacttt
     5281 aaaaagaaac tctcactcca attcaataga gtgagagcaa cgtaaatata aaaactccaa
     5341 ggagttccta tctcttccga ttctttttgt ttttctttct ttttgcttgc gctttttgaa
     5401 agtcttgtgg cttcttggat ttttttaggt cttccacctg aaatgtctgg ctagcaaaaa
     5461 tttccataca ggtactataa gcagacaaca cctctccact cattcccaaa aatttgaaaa
     5521 tagtttctgg atcttcctct aaaccaccag tacgcagcat ggcataaatc aaggcacgca
     5581 tgatttttag atcactaggc gataagttag cagaagaaat ttgtccttct tttttagata
     5641 gcatggcgtt catatcagat tcaaattgcg aataatctcc accatacaca tctgctataa
     5701 attccatcgt ttgcatagta aatgaaatag ggaattctgc gccttgaata attacaacag
     5761 cagaattttt taagtcttca acgtgaattc cataatcaga taaccgagcc attaacccgc
     5821 acctccaact ttagccaatg ttttccactg ttcttcatcg tatacaggtt gagcaatgaa
     5881 tttattaaat aattctagag aagctccgtc tctatttgaa tcaaaacttg catacatcac
     5941 attattgtat ttcagtccga tggaaaccag atttgcagtt acatcgtcaa tttttgtttc
     6001 ttcctctgca gtggcatact cttcgtcaat cacattggat agttgtgtat taggatacca
     6061 aactgctttt ttaccgccat tttcaatatt tccaataaat ccaaaggcga agtacggaaa
     6121 ttctcgtgcg gtatttttgc taaacgttac tccgctttta gcaactaatc ctttgatttc
     6181 atccatcact tctatcggaa tacccacgtg atccaacgca agttcatgtt ttgtttctcg
     6241 cgacacacga cgaaacattt tgctggatgc ccatttttct aatgctgttc cattcccttt
     6301 gacaccgatt tttgtggcaa ttggcaatcg taaaacttca ctataagtcg gtgcagttcc
     6361 aacagaatct ggcgttgcca tcatcgcaat taaaatgtcg tccaatcctt caaaataaaa
     6421 agtatcttgt tttcccaatt aaaatcaccc ttcccataaa tcaagtattt ttctagtcat
     6481 aatttcttca attttttctt tgttttgttc atacgtacca cttgcaaaat gttgggcacg
     6541 ttgatttgtt gtgccatttt cggcaaagcg ccagtaaaag gccgtctctt caaattgaac
     6601 tttcacttga tcgttttcaa ctactacttt tatttgatcg cgcatatgtt tcttttttaa
     6661 gagcgactta ggaatattag gaagcaactg ctttagataa aagttagctg cttcttctaa
     6721 agattccaac gataattttt tcggatcaac ttttgaaagg tttcctaaat aatccgatat
     6781 ttcagaaaaa ccattcttat tacttggcat tttccacaca cctcacatat gtgtaatagt
     6841 tggttacggt atcgtcgttc tcatcacctt gtatacctgt aaaatctgaa tatggaatgc
     6901 cagcattttg cagcgcttgt tcaataacaa ctaaatcctg ttctgttcca agtgtaaaaa
     6961 aagagacttg gtaataaggt aattttttat agactttacc ggatgccatt tttttgctgt
     7021 tactcacatt tgagtacaca atgtatggat acatcgtccc taatctggct ttgtctctga
     7081 acactgctaa ctttgttgat ttcagcgctg ttttcaattc atcaaagcta atcgacataa
     7141 gctaaactca actccatttc tcttgcatcg ggattcgtat aaatgcgagt aatgttatac
     7201 gttacagaat caattttgag cgcacttaat ttctctgtga tggatttatc ccatctgact
     7261 ttaattcgtc tgacaacgtc tgtcttggct tgctgtgata aatatttttc ttgagaagtc
     7321 acaccgagtt cttcatagaa tattagacgc ttaaattcgt aaattgtagt tggacgatcg
     7381 tttccgtctg ttcctgtttt gatgtctagc aattcggctt tccatctgag attattagtc
     7441 tgtctcttcg gcattttgaa tcgctccttg cacgataaat ggcgtcatgg cattcatagc
     7501 tttgtcgagt tcatcctctg aaactctata ttcataggca atgccggcaa ccatcaaaat
     7561 aagatattct tgttggccac cagttgctgt tttgacataa tcttttgcca tatttaaata
     7621 aaaagagagc aaagaatcat ccatgccctc ttcaaaatga atatgtgatt tgaatttttc
     7681 ctctaaagac aattctttag tttgctcttc catcttaacc accaactggt tttgtaattt
     7741 cgtagcgata tactgccggt tcaaatggag aataaaccaa ttgaccatct agcaagttgt
     7801 aaatttggaa tccaatttga tttttaccag agaatttttc aacaagtttt tgaatttcca
     7861 aggcaccaat aacttcttga attttaaatg cagaaaaatc gccaaaatat aaaactggcg
     7921 tgtctggttc acccttttta tctgctgcat ctgtccaatc cacaggatag ccaactaatt
     7981 ggtaaccaat tccaccttct gcttgtgtga atggccgcaa caaaggaaat ccatcatctg
     8041 ttttcatttt ttcaatggca gtcaaagcag ctcgattaat aataaagcgt ccctttttca
     8101 tcacttctgt cactggtgta tttttaaatt cgattaatgc atcatataat ttttgcccag
     8161 cacctgaagc agttagatct aaaggttttt taaatgctac agcctttttg gctaatgcac
     8221 caggattttc atttccagcg tcatcaccat tgaacatata attgatttct ttacgcacat
     8281 aagctttttt caattcttcc acaacaatat cttcaactgg aacaccagac atttttaata
     8341 attttttagt tactgttgcc aaagcatcga attcggcagg attaagcaaa atttcatcaa
     8401 actgaatagc tgtttcagca atatcagttg aacgctcttt cttgtttaca ttcgcatctg
     8461 ctttcttcac aagaattgga tatttgacat ctcctgatgt tcgcaccact gttccgtatt
     8521 tacgaagtaa attttcttct tgagcataag taataacttc agatgcaatt acttctggga
     8581 cagtaactga accgttgcca gcttcaatcc ctaaagctcg agcttctgct tcagaaatat
     8641 ttccagctac aaaattagca aatgcttttc gtagttgttg atctttttgt ttcttggtca
     8701 tttttgcacg tgcctccaat ccgttcttaa ttgatccaag taatccatct cgttgctgtt
     8761 gagtaatcat tccagaacga ttttctgaac tatcttcact gtctgaatct tcttcttgat
     8821 cgttgtcttc accagaacgg ctttcgtctg aatccgtact attcgattga tcatctgtat
     8881 tgtcgtctgt ttcatcagtt ccagaatctg cgcctaattc gtctttaatt ccgttcaatt
     8941 catcaataac actgtcaatt tcttctttca cggcttctaa atctgcttcg cgtaattctc
     9001 ctgattcaac tttttcacgt aattcagtca atcgttgctc acgacgtgcc ttcatttttt
     9061 tcaataattc tttatccatg tatttttcct cctacgcttc tagcgcttga ttaatttttt
     9121 tgattaattt ttttctttct tcgacgtttt tttctaattc atcacgactt cttaatgcag
     9181 cttctgtatc ttcgtatgct ggcaaaggca caatagaaac ctcgtataat tccacttcat
     9241 ggattgttcg aagcattggt tcagaattgt agtcccacgt ttcttcagtc ggcacaaaac
     9301 caaaactaca ttggttgatg tctcctcgtt ccatagattt aactaagtcc cttgctaccg
     9361 ttgtgtccgg taaatcaact tcgaatttca aaccacgttc atcttcttca aggcgaaggg
     9421 ttccgctttt agtacgtcct agcacattgg accaatcgtg attgaacaaa caacgaacat
     9481 ccgaattact aattgccttt gagaatgcac caggaacaat cacttcgctt aagtcatccc
     9541 ataaaagtgt ttgactgttg aatacagcag cgtagccgct aatggtcctc gtatgagttt
     9601 cttcatcgga acgtgttgaa agattggtga tgtcaatcgt gcgaatttcc ttcttcttca
     9661 tttccatcac ctcctttcaa gtcttgatca ttcgttggta aggaatcatc tgttgcattt
     9721 ttctggccaa tcctagataa gtcatttgaa atatagatag cttgtgtttc tggagtattc
     9781 tgtttaggaa aaccaagcat ttctgccacg ttatctggac ttgtaatccc ggtacgaacg
     9841 atgttgtagc caatatttgt ttttgttgag taaggaacaa aatccaaaat attaattttc
     9901 cattccactc tatagccaga attaggcata aaaaaaagag cggtgtaatg ttcgctcttg
     9961 tttttcaata ttggtttgat tgctttgttg tgcagataca tcatcgcttt ttcaatatct
    10021 gtcttcatca gcgattgata cgtatcaaca ttgattccta gaaattttcc taagtctttt
    10081 ttgtaaacac ctaaataatt caaaattgcc gcgtcatcaa caggactttt taatgtctcg
    10141 atggaatatc cttttcccaa aggaatcatc ttaacagaat gatcactctc attttgcgtt
    10201 ccttccagtt gatccaatat agctttgaca atttttgttt gggcgctatt atttggattg
    10261 atgtgggcgt ctagtttaag catgaacgca agtaaaccgc ctttagtata tttgtccgtc
    10321 aaaacttttt cagcgctcag aacgccttct agagtgtttc ttgcaagatc aattattcca
    10381 gcacctttta atgaatcagt tccgatgttc ttaatgtgtc gaatcatttg accaggtatt
    10441 ttttgaccat tcatttcaaa ttcttcttga agtcgttcat tgattttagt tgttacaccg
    10501 tacgccaaat gaagctgatc cctatccgtt aatgggaatg tctcaccatt gatcaataaa
    10561 gtatttgttt ccaatttggt aaattcgaat cctgtcaaat aatcattggg actcttcaaa
    10621 atatttagta agtgatgatc tttgacttcg ttgccgtcgg gaccaataac aattggtgtg
    10681 gccaatgcca cctgattaga tatgtcttga actaattcat aaacatcaga agattccatg
    10741 atagatgaat ccgtcacata tctttgacca taacgtgtgt agtgtccaaa aatatcctcg
    10801 atatatccac gtttttccat aaaagaatag actgcattcg ataaccgatc acgtaatttc
    10861 aatttttttc accgcctttc tatttatcta tagatggaac ttaggtaatc atctaactca
    10921 tctgaatcaa tatctgtcat ttgattcatc gtttccttat gaccacacaa aaacgccacg
    10981 aacccatcaa tctttttctt tgattgacgt ttacttggcg ctttttgtcc attgatgtta
    11041 gtaattgcta caacgttcaa agtgcaataa aggaataatg gattatcaaa ttgaattcgt
    11101 ttctcataaa acaaccgttc gacatcgtca aaaggagcat tcaatacttt aggatattga
    11161 gcaacttcaa cgcattccaa tcctaagttt tctaatttct caacaagttt gtcactcatc
    11221 gctggatcat aattcacttg ctgaatatca tataaattca tgcagtcctc tatgtactgc
    11281 aaaatctgat cttgatcaat catttttccg tcgcaaaatt caacgaaacc ttgttcagcc
    11341 aaatcactgt aaggaacatt atcttctttt tctcgaaact ctaaatcttc attcggaata
    11401 aaataaagtt gctttacttt aagaaccgct ttaccatctt catcccatgt tgggaagttt
    11461 aaagatacac aggtcaaatc tcgtgtacgt gataaatcta aaccgatata acatggttcg
    11521 ccacttaaat caccaagttc ttgtgtggta actaaacatg gctctacttg atcctgttca
    11581 aagaaattat ccgcgccgtt cacaaataca tccaagtgtt tcgttagaaa ttcagctttg
    11641 gaatgagctg accgttgcgc tgttttaaat gccgattcta aagcagataa atcgactgat
    11701 attccccagt taggattgca catttcccag acttttctat ccgtccaatc ataattttta
    11761 tttggctcat agattagaac aaagtttgaa tcattatcat cacgtttcaa cacttctttt
    11821 gcttcgcgat atacacgcat tccaacagac gacgaacctt tcccagcagt tgagatatta
    11881 aacatcaatg gctgtggtaa agatatctga gcagacttaa aattgtcata ctgttccatt
    11941 ttctcctgtt tatgcaattc atcgttcaat acaaaatatg gattggatcc ctcgatatta
    12001 tcaatattct tggtttgaac aataaattta tttgagtaag ccatatcttc atgaatatag
    12061 tcataagtaa tactagaaac agttcccttt ggccccctaa atattttagt tccttcaagt
    12121 aggattggat tgtttaagat tgtaactgca aaaggtttgg cagcatattg cgcttgagca
    12181 aaatcagatg cgcaagcata gcaatcaact gataacgccc cttctccgta cattgcatat
    12241 cctaatgaac cgacagcaat caatgtttta ccattctttt ttggaatctg gacataagcc
    12301 tcacgagtaa cgcgtacaat ttggcctttt tcattttctt taacccaacc ataaatccaa
    12361 gaataaataa atttttccca gggttctaaa agaaacggtt ttcccaccat ttctcctttt
    12421 gtgtgaacaa taaatgattc tacccaatcc atcatttcat tcgcgcgatc tacatcaaac
    12481 caaatatctt ttcttttttt ccactgatac cagcgatcta ttgctaaacg aacggtctta
    12541 ggatacttct taggtttctt tcttacttct tttgcaaata aatcagcata atttacacca
    12601 ggttcaatca tttttcagca cctgccttct tacgccattt atttctgtgc gctgctagtt
    12661 catctactgg ctttacttct gggcgtgtaa tttcttcatc ttttcttgcg gtcgatcctc
    12721 cagcaattag tctaccagtt tttgctttgt ttgttaatcc taataaatct agagctttca
    12781 tcttcttatc tgcccaagtt tctacttgtt gtgccaatgg atgttttgat tgattagtag
    12841 ctcctgattt attcgtgaat ttttgcgtct ccggaaatcc tttttccttc cacaataaat
    12901 atttgtgttg gtaaatttca aaaatatcca agtatgattc gattaatgga tcaagagtga
    12961 tggtgtacaa atcagacaaa ttcattattt ctaagatacg agctttttca gcacttactt
    13021 tttcatcaat aatcgcttta cgttgcgctt tagtcgtcat ttttgtatac accccccttt
    13081 gttttttgaa aaatttgacc taacgatgcg cgtgactccc cgctacccta tctccccacg
    13141 cgaaaaaatt ttgaaaatga ataggggggc ttcaattgaa atacgaagga aaaacttttt
    13201 tgtcttccgt ttcgttttca acaattggat gacattttga acataatagc atgagattgt
    13261 ttggatcaag cttaagcagt tcgttgtctt tgattggtac aatgtgatgg acgtgtgctc
    13321 tctttccaaa tatgaactga ccacaccgct gacaatgacc accttctctt tcataaataa
    13381 attgacgcat atctttccat gcttgcgttc gatagaatgg tttgttctca tgatgataaa
    13441 cagactttgc ttgctgcttc ttcttgcgtg atctgcttga tctcttgtgt tcagtacagt
    13501 agataccctt tgctattttg ttcgtgcatc cgtcaaactg acagtatttc attctacttc
    13561 acgaataaga tttatgatat cgccttttgc acggatagca ccaggaatat caataccatg
    13621 tttcttagca tatgcacgca attcttttgc agtcatattg tccagttcat ccgtatcttc
    13681 agtggactga tcattagtag cttcgtctcc atcaaaatta gcagcagtgt ttccatcgct
    13741 atcaagaatt tcactgctat gagctatgag ttcgccattg acagcaacaa atgatttgcc
    13801 atcactcaaa attccttttt cttcttttac ttcaaaattt ggttcttgat ctttcggaac
    13861 aactactgtc cttttctttt ctgaatccca atactctgtt ccactaatgg atgttctaat
    13921 tttgatcatt gccattttaa ttctctcctt tgtaatttgt acggattact tttgcgccca
    13981 ttcgctcata ccattcaatc gtttcctgca gattgggtag agtgtgtgac aataaagaaa
    14041 taactaacgt attcattcca gttctgtaat catcattctc cacttgcaca tgtgcatgat
    14101 taccattcca attttctctg tacggactat tctctgcttc aattgctttc ttataaactt
    14161 tagccaaact tgattctact tcaatactaa gtaccgcttc atgaaaatca ttcatttgtt
    14221 tactctccta tcagatattt tgtggtatga tttataaaaa agatgcgagg tgttttaatg
    14281 cttcaagaag ttaatattaa gtatcgtgat cgtcaaaata cagagacaat ttatttgcca
    14341 aatagttgtc cgcattgcgg aaatataatg actccgtatg tgtattttgg ggtttcatca
    14401 tatagtgcgt tcgataatga tagaatcttt ggcgtattag tacagtgtat aaatgatgag
    14461 tgcaacaaat tttatagttt acaatttata aatacgttta atgaagatga aggatattct
    14521 gaaaatattt taattaaaga ttattaccgt ccgccgatta aaatagattt accagaaaat
    14581 attgaaaaag tttctcctac atttgttgat atttatactc aagccacaca agctaaatct
    14641 gagcaattgg aacaaattgc tggagttggt tatagaaaag ctctagaatt tctaattaaa
    14701 gattatgcaa tatctaaaaa ttcagaggat gaagataaaa taaaaaaaat gttattagg
//
LOCUS       DAMEEU010000069        14443 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.070, whole genome shotgun sequence.
ACCESSION   DAMEEU010000069 DAMEEU010000000
VERSION     DAMEEU010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14443)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14443)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14443
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.070"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..83)
                     /locus_tag="PB779_002190"
     CDS             complement(<1..83)
                     /locus_tag="PB779_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heptaprenyl diphosphate synthase"
                     /protein_id="HDE0739702.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIP"
     gene            complement(97..513)
                     /locus_tag="PB779_002191"
     CDS             complement(97..513)
                     /locus_tag="PB779_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HDE0739703.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            complement(970..2904)
                     /locus_tag="PB779_002192"
     CDS             complement(970..2904)
                     /locus_tag="PB779_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDE0739704.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            3185..4141
                     /locus_tag="PB779_002193"
     CDS             3185..4141
                     /locus_tag="PB779_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HDE0739705.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            4231..5334
                     /locus_tag="PB779_002194"
     CDS             4231..5334
                     /locus_tag="PB779_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HDE0739706.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            5347..6300
                     /gene="menA"
                     /locus_tag="PB779_002195"
     CDS             5347..6300
                     /gene="menA"
                     /locus_tag="PB779_002195"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HDE0739707.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFALVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(7235..8581)
                     /gene="gor"
                     /locus_tag="PB779_002196"
     CDS             complement(7235..8581)
                     /gene="gor"
                     /locus_tag="PB779_002196"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HDE0739708.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(8715..9968)
                     /locus_tag="PB779_002197"
     CDS             complement(8715..9968)
                     /locus_tag="PB779_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDE0739709.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(9974..10897)
                     /locus_tag="PB779_002198"
     CDS             complement(9974..10897)
                     /locus_tag="PB779_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HDE0739710.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(11118..13610)
                     /locus_tag="PB779_002199"
     CDS             complement(11118..13610)
                     /locus_tag="PB779_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HDE0739711.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(13617..14084)
                     /locus_tag="PB779_002200"
     CDS             complement(13617..14084)
                     /locus_tag="PB779_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HDE0739712.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(14220..14293)
                     /locus_tag="PB779_002201"
     tRNA            complement(14220..14293)
                     /locus_tag="PB779_002201"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14257..14259),aa:Arg,seq:acg)
     gene            complement(14351..14424)
                     /locus_tag="PB779_002202"
     tRNA            complement(14351..14424)
                     /locus_tag="PB779_002202"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14388..14390),aa:Pro,seq:tgg)
BASE COUNT         4236 a         3009 c         2550 g         4648 t
ORIGIN      
        1 gggatcatat tttccaataa accaatgatc actccttgtg caacaagtag cgaaatataa
       61 atcatttttt gtaatttact catggtgtgt aaaggtctaa taaatcagac tgtcttcgtc
      121 acctccatct gttgaacgga cttcgatcac taatttatgt ggcaaacaga cgatggtttc
      181 gccatttttc gttgcccagc ctcgacgtac gcagatctgg tcatcgcaat ctgcttcttt
      241 tatccgtact cgatcgccat ctatctcgat caagttataa tctccgtgtt catctttgta
      301 agtatatgtg ttgctctctt ctccagccat caaagggaat gttttgattt ctgtgccatc
      361 cacacgcagt accgcttctt tttctgctgt tgcggtgttt tgctgaagac caaaaatcat
      421 gactggtaaa aaagaaagaa cagtcaaaag caaaataata aaaacatccc aaggtttgag
      481 cagacttttt tcagcaaatt ctttaaggct catttttgtt ctcctttttc cagattaact
      541 cacccaattt tagcataaaa acaagaggtt gtgacacctg tgtcttgctt tgagtaataa
      601 gaacgaagaa tagaaaacag ctttccatgt tttctaattc tttgggctta ttaccgagaa
      661 gcagcaggtg gaacaccgtt tataacaaga ggttgtgaca gaagtgggca acttcaagaa
      721 ataagaagga atttacgaaa attacttttc aagtttttgt gaaatttcgg cttatttttc
      781 gaagaagcta cttctggaac accgtttata acaagaggtt gtaacagagg ttgtgacacc
      841 tgtgtcttgc tcatggaggc ttatctcggg catcttattc ctttaatttt acataaaaag
      901 gaggctgtga cggtttgtct cagccccttt ctattgaaat cttgcattca aataacgttc
      961 tttatctatt tatttcttgc cgtactggga acttggtcta ccgtaccacc aattacctag
     1021 tgtacgttgt agccatggaa ttacccagcg atccaaccca atcgcacgtc cggaaccgtt
     1081 catcaatgcg aaagcaacaa aaatgaacca aatgtttacc cagtaaaaca tgcctgataa
     1141 gcagaacgtg atcaccaata caatcgttgt cgcactgcat agccatgtga ataatccagc
     1201 aatcaatgct aatgccaagg caatttcaaa gaataccatg aatttttgga agaacattgc
     1261 tacatcattg tttggcatga tcacttgcat gatctttgtg aaccagtctg gtgacttctc
     1321 aatcacagcc attggttctt caccgtatgc ataactcaaa ccaaaatgtg cagcttgagt
     1381 cgctgcttct ccggcacttg cccctgctcc gctggcagct gtggttgcat caccagcagc
     1441 agaagcacca ctggcaacat ctgttacatt gtattcccat gtccaaggga acacactgtt
     1501 tccagtgaac catgatcctt caccaaacca agtacttggt ttgaacactt caccattccc
     1561 aatgattttt ttggaagctt caacgaacca aactaaacca tagaaaatac gaagtggcac
     1621 actccataag acattgccgt aacgagaaga atgtcctcga gtcacgttgc gatcatcttt
     1681 gatatggaaa aactcatgca ttaaatattg gaacatataa taaccagaac gaatatcaaa
     1741 gaagtatttc aaattcacga tatgtttcat tacgatagct aaaaatccgc ttaaatggat
     1801 cttatcaaat aggttagcta ccccccattt ggcaccaata gaaaccataa atccttgata
     1861 gtttccttta aatttatgct tttctccgcc tttgatcgaa gccacgatat tcgctgcggc
     1921 tgtgtgtcct gtttgttcag cagcttgaac gatctgcggt gtcggtgttc ctgggaattc
     1981 ttcataaaag actaaatcac caatgatata gatgttttta tcttcgtagc cttttgcctg
     2041 catatattca ttggcgatca accgctgtcc gcgtgctgat tctaatccaa agtcagcagc
     2101 gtcagaagtt cctttgacac cagctgtcca aatcagtgtg tgagtcggaa tgttgcgtcc
     2161 gtctttcaat ttgatatgat cagcagccac ttctacgatt ggtgcattca ataataattc
     2221 cacgttgtgc ttacgcaaat agcgttcagc ttttgcagca tcatttcgat ccaacatatt
     2281 caagatcgtc ggcattgcct ctacgaccat cagtgtgatt tcgtttggat ctaatttata
     2341 atctttggct aggcgatttt tccagtcgat cagttcccca atcatttcaa taccggtaaa
     2401 tccagaacca cagacaacga aagtcagcat ggctttacgc agttcatcat ctggttccaa
     2461 tgcagctttt gctactgtct tctcaatatg ttcccgaatc cttacagaat cttcaaatga
     2521 ccaaagggtg aatccgtgtg ctttgacacc aggtgtacca aagtcattcg gctctccgcc
     2581 cattccaagg atcagctgat caaaaggata ggaacctaat ttggtcttga cgatttttcg
     2641 ttctttatcg ataccgatta cagtgtctgt gacaagttgt acattctttt gacgagcaaa
     2701 caaatgctgc agatcgtatt ggattgcttc tggttctaca cgtccgccag ctacttcatg
     2761 caactcggtc atcatagtat ggtacgaatg acgatcgatc agagtaattg ctacatcttc
     2821 ttttttcagt ttctttgcca agtattttgt agctgaaaca ccggcatatc ctgctcctac
     2881 aacgacaata ttttgctttg ccattgatca tccgctcctt atagactatc tatataatga
     2941 atatatgata attcttttag tttgatactt attacacaat ctccatatat tatatagatg
     3001 ttctgttctt ttgtctaact ccttttggat ttttttcaaa ttttaaaata aagcgttttt
     3061 tcacgaaatt tgctgaaaga aaacgtttga aatattacat gggttattta tcaaaaatag
     3121 ttgacttata ggctaaaaag attagaatgt ataatgaatc acaaagaaaa attgtggact
     3181 agaaatggaa tggtggggta ttaaaatgaa gaaaaaacgt tttgtaactg gatttgccgt
     3241 attagcattt tcagctctag tgttaggcgc ttgcggcgca gatgacaacg gaagctcaaa
     3301 ctcttcttct gaatcatcta cagcacaatc ttcgactgca aaaagcacaa cagaatcatc
     3361 tgcaaaagtt gtagctggcg gagatttgca agacggcaca tataaattag aagaaaaaaa
     3421 ttattcaaat ggttaccgtg cagtctttga aatggttgta aaagacggca aaatcactga
     3481 atcaaaatat gataacgtca atgaaaacgg cgaatcaaaa acaaaagatg cagaatacaa
     3541 caaaaacatg gaagcaaaat ctggcacaaa cccagaaaaa tacattcctg agttgaatga
     3601 ccaattctta aaagcacaaa gcgcaagcgg tgtggaagtc gtaactggag ctactcactc
     3661 atctgaaagc ttccaaaact acgcacaaca attgatccaa gctgctcaag ctggtaacac
     3721 agatacaatc gaaatcgaca atggtgctga tttgaaagac ggcacttaca agcttgaaga
     3781 aaagaactac tctaacggct accgtgtgca attcgaaatg acagttgctg gcggcaaagt
     3841 aactgaatca aactttgatt atatcgacaa agacggtaaa tcaaaacaag atgatacaga
     3901 atataatgaa aatatgaaag caaaaagcgg tacagaacca aaaacttaca tccctactct
     3961 gaacgacgaa ttcgtcaaag caatgggcga agaagatggc tcacctgcta atgtagaagt
     4021 tgttacaggt gctacacaca gctcacattc attcatcatg tacgcacaac aattagtgaa
     4081 tgcagctgaa aaaggcgaca ctcaaacaat cgaagtagat aatatcgtaa cagaaaaata
     4141 atcacataat catactaata aaagttggag ggtgggacga tagccagatt aggcagtcgt
     4201 ctcacctttc aaaatgaaga gaggaaaaag atgcggaaaa aactactatt ttccttaatc
     4261 acactgggca tctcttttat ggtgctaact ggctgcagca actcagcaaa taaaacaacc
     4321 actgaaagtt cagcagctac caagatattg aaagatccat attctgatga acagttcttg
     4381 ttagggactt acgttcgtat ccgtgtgtat gatgaaggca aagaatcagc attgaaacct
     4441 gccttcgatc gagtaaaaga acttggtgat aaaatcacga tcaatcaaaa aggttctgag
     4501 atcgatgaag tgaatgagca agctgggatc aaaccagtaa aagtttctga tgacgtctac
     4561 acgttagtca agcgggccta cgaatatagc caagattctc aaggcggatt cgatatggcg
     4621 attggtgcaa tcacacaatt atggcgaatc ggttttgatg acgccagaaa accttcccaa
     4681 gaagaaatcg atcaggcatt gaaattagtg gattatcata agatcgaact aaatgacaaa
     4741 gaaaaaactg tttatctaaa agaaaaagga atgatcatcg atttaggtgc aatcgccaaa
     4801 ggttacatta cggacgaagt agtgaaagtc ttgaaaaaac aaggagtgac cactgccatc
     4861 gttgacttgg gcggtaatgt ctatgtctta ggccacagcc caagaggcga aaaccaagac
     4921 tggacagtcg gcatccaaga tccgaacatg gctcgcggat ctgttttagg ttctattaaa
     4981 gaacggaaca aaacattagt tacctctgga atttacgagc gttatttaga agtagatggc
     5041 aaaaaatacc atcatttgtt tgatccaaaa acgggttatc cgttcgacaa tgatatcgca
     5101 agtgtcacga tcataacaga taaatcaatt gatggtgacg ggttgtctac agcagtcttt
     5161 tcaatgggtg tgaaaaaagg actggaatac gtcgaaagcg aattgaataa cgggacggaa
     5221 gcgatcttcg tgacaaaaga cgataaagta tatgtgaccg atccaatcaa agacaccttc
     5281 aaattatcgg aggactccca ttacacgatg ggtgaccgtt ctgaactaaa ataaggagta
     5341 cgaaccatga cactaaaaat ctttttagaa gtagttgaaa tacgaacaaa ggtggctagt
     5401 gtatttcctt ttgcggtagg ggtattattc tctatcgctt tttttcatga gatacattgg
     5461 ctaaacactt ttttattttt tattggaatg ctagtttttg atttagcgac taccgctatc
     5521 aataattaca tggattatga aaaggctcat tctgaagtat ataagtatga agaaaatgtc
     5581 attggccgca gaaatctatc tcctgtattg attcgaaaca tgattttagc tatgattgca
     5641 tttgtttttg ttatcggcgt tattctaacg atcaatacgg gttggctttt acttttgatg
     5701 ggatttatct gttgttttat tggagtattc tatacattcg gaccgattcc tttatctcga
     5761 atgcctttag gggaaatttt cagtggggtg actatgggcc ttggaatttt tgccatggtc
     5821 gtttatgtca atacattcgg ttcagatgtc tatgatctga cagtcaactt ttcatctgga
     5881 caatttgctt tggtaggaaa tctttgggct atagcagcaa tcgtattagc ttccttaccc
     5941 ttggtgttta cgattgccaa tatcatgttg gctaataatt tgcgggatct tgaccgtgat
     6001 attgaaaatc atcgctatac actagttttt tatatcggac gtcctgcggg aacagtctta
     6061 ttccagctat tgatgtatgc ttgctatttc gtgattttaa tggggttgtt gagcggtatc
     6121 tatgaatggc cgatcttggt caccttcttg accttgccaa ttgtgaagaa gcatttggat
     6181 caattcaagc aaacgttacc ccagcctatc agtttcagct attccatcaa aaatatggtc
     6241 ttattcaatg ccagttatgt attggggcta ttactaacaa tcattatgca agccatttaa
     6301 cagcatgaag aggttgtgaa aaaactgccc tgcatcaagt aataagaaca gccaaataaa
     6361 aatagctcct tatatttttc gtttggttgg gcttattacc gcagatgcaa gcttttgaac
     6421 accgtttatc aggaggttgt gaaaaagtcg cttagtttcg agtattaaga aaaattttgt
     6481 gaaaatggct ttccacattt ttgcataaat ttggcttaat accgagaaac tggcttttga
     6541 acaccgttta tcagaggttg tgaaaaagtc gcttagtttc gagtattaag aaaaattttg
     6601 tgaaaatggc tttccacatt tttgcataaa tttggcttaa taccgagaaa ctggcttttg
     6661 aacaccgttt atcagaggtt gtaaaatcag tgttttgtcc tgagtattag agaaacaaat
     6721 ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgaagga cagctgattg
     6781 aacactattt gttcggaaaa agtgactaac tatgacacaa tttttttcac agtccctttt
     6841 ttcacttgat ttgattcgta ccagcgaact tgacgagaac tttcttggtt tggtaactat
     6901 atggtattct tttaacatcc tcgtttgctt cttctaattt atttatacaa agtcacactt
     6961 ttttaaacat ctgttcttcg atacatttct atttctttta aacatcgata ccaatatttt
     7021 gaacttaaga gtgcatacca aatggattca tttactcttc gtcagttacg aagataatca
     7081 aaatctccaa cttccctact tatttcgttt tgagaattat cgaagcaatc ttacataaat
     7141 aactaaaaaa caaaaaacca gaaaatcagt atactgattt tctggtttta catggtttgt
     7201 tcaataaaaa gctgttggaa ctgttaatat taaattatcg catcgttacg aattcttccg
     7261 ctcctgttgg atggatggct actgtattgt caaagtcttc tttagttgca cccatcttga
     7321 tagccacggc aaaaccttgc agcatctcat cgacaccaac accaatagca tgtaagccga
     7381 cgattctttc ttcttttccg acacagatca atttcatttc gcatttttgg cgataatcat
     7441 ttaatgcaaa gtacattggg gtaaagcgtg aacgataaac tttcaattca ttttcgccat
     7501 atttttccaa tgcttcttct tctgtcaaac caattgttgc aattggtgga tgcgtaaaga
     7561 cgactgtcgg aacaagttta tagtcaagat aagaatcttt ctttccatta aataaacgtt
     7621 ctgataaacg tctaccagct gcgattgcaa caggagtcag atctaattta ccgatcacat
     7681 caccaacagc aaaaatatgt tcatccgttg tattttggta tttatctact ttgataaacc
     7741 cttttttgtc caattccaca tttgtatttt ccagacctaa tttttcggta ttcggtacac
     7801 gtccaccggc aaaaagtaca caatcaccag ttaaggtttc accattttca aatagcaccg
     7861 tatattcgtc attgttttta gtaatttctt tagcaatatg atgtgcgtaa gtttttattc
     7921 cagcttcttg gtacatttgg atcaaattgt ccgaaagcat tttatcaaac gttctaagtg
     7981 gtcgttcttt tcgatatgcc cacatgactt cactacctaa accacgaaat acacctgaaa
     8041 gttcagccgc aatgtatcca gcacctaaaa cgattgctct cttaggtaac tctgttaatt
     8101 caaaaaatcc atttgaatca attgcgtatt ctccaccagg aatggtcatt ttacttgcac
     8161 ggcctccagt agcgatcaag attttaggag cacgataggt ttcaccgttt acttcgatcg
     8221 tttgactatc gataaaagta gcgtaacctt ttatagcctc gacatgattg ctatctaatc
     8281 ctctttgata agcaccgtgt agaaaatcaa tatatttttc tcgtctttct actagaccgg
     8341 cgaaatcaac attttttaaa tctgcttgga taccgtaact tgaggcatct cgttcaattg
     8401 tttccaaaat cgtacttgct tgccacataa cttttttagg tacacaaccg acgttgacac
     8461 atgttccgcc caattcattc gcttcaatca gcaaaacttt tgcgccatgc atccctgctc
     8521 tgtttgctga agcaataccg ccagagccgc caccaattac gatgtaatca tatatttgca
     8581 ttttgttcct ccttattgaa gagatcaatc aaaaccttta tttaacgatc ctttttctac
     8641 agaaaacaag tgtaacactt ttcttgaatt ttgtatgcga agatgcttaa aacagggata
     8701 tatcagcttt ttccttattt acgttttcgg atcatatctc caggtttcac cggctgtgcg
     8761 actggcatag ttaaaatcat cattggattt ggtgctcggt caatggattc gccttcttca
     8821 ttatgcataa cttcaacggt ttgactgaaa tgactgaatc ctggaccata aaattcgatt
     8881 tcatctccta cagaaaacaa gtttctctga cgtatcgtag caatctgtgt tgcctcatca
     8941 taagataata cttcaccgac aaatttatat actgggattt tacgacgttc accgaataat
     9001 tgttcgtttt cagttggtgt attgtagtaa aaacctgtag ctaattctcg ttgtgctact
     9061 ttccataact cgtcgatcca ttcttgcttg cagacatagt tttcaggatc ttccatataa
     9121 ctgtctacag ccgctttata gacatttgac accgtagata cataatggat cgatttcatt
     9181 cttccttcga tcttgaagct gtctacgccg ttttcaatca attctggaat atgttcgatc
     9241 attgacatat ccactgcact catcgagaat tcttcttcca cttcgcctgt atcagttaaa
     9301 ctgtttcgtt cttgaccaaa aggcatatcg aacaatccat acttccagcg acaagattga
     9361 gaacatccgc cacggtttgc atcccgcatc gacatatggt tggacaatgt gcatcgacca
     9421 gaataagaga tacacatggc accatggata aatgcttcga tttcggtatc cgtattttta
     9481 cgaatctctg ccacttcctc cattgaaact tcacgagcta aaacgacacg ttccaaccct
     9541 tcttctttcc agaattccaa tgtctcaaaa ttagttgctg aagcttgagt ggataaatgg
     9601 atcggcagac ctggggcttc tgtcgcacaa atttcgatca aagctggatc agaaacaatc
     9661 actgcagaaa taccgacatc acgcaaactg cggaaaaatt cccctgctcc atcttcattt
     9721 ccttcatggg tgaccatatt agcagcaacg tataccttcg catcatgttc ttttgcaaaa
     9781 gcaactcctt cagccatttc ttcataagta aaattacctg cacggcttct taaaccatat
     9841 gcattcccgc caatatatac tgcatctgct ccataatgga tcgcggtttt taacttttcc
     9901 agtgttcctg ctggcgctag gatttctggt cgtttcaatt ttctttttac tgtcatttct
     9961 ttcatcatac tccttatttg atagcagaag gatcaatata aaagaatcct gtatctaatt
    10021 cacggttttc aggatgcaat ttactgattt cgctagtcat tttttccgct ttttcttgat
    10081 cccagctacc ttctaaaatt tgtttttttg cttcggcgaa tagtcgagtg atgtttacga
    10141 atttttcgcc tggagtaaat aatccgtcca atttccatgt acagtaatga tgctgataaa
    10201 gttcattcaa ttcattcgag agattcagat cattgctggc aaaaatatgt gtgccatgac
    10261 tatcttcata aatagaataa tgtgtctctt cttttttagg ttccgagata aaaagacctc
    10321 tttcacgatc tttttgttcg tcttgtttcg tatagttata gtaattctgt agcagtggac
    10381 gtttggattg atggatgcat gtagcaccat acacaagggt ttctacagga atatcgagtt
    10441 tttcttccat cgccttcatc tcttcaaaag gaacttcacg agcaagtact gctccaactg
    10501 cgcctttttt cgcccagaaa ttgatttgac gtgcgctcgt tactaatgtt tcagcatcat
    10561 aaatatacgg tatacgcaat tcaggatttt ttttcatcgt ataaataata cctgtatcac
    10621 caactgtgat cacatctacg tttatttctt ttaaaaaagc caaatattca ggtacatttt
    10681 tcattttttc aggatgaatg atcccattta cagcaatatt cgctttttta ccatacttgt
    10741 gtgctaattc taccaattgt cgctgttctt ctcgtgtaaa tgaagcaggc agacgcaatc
    10801 caaattgctc ttcaccgaaa tatagtgtat ctgcacctgc agcaagcaac tgttctgctt
    10861 gttcaatagt ttctactgtg gttatgagtt cgatcataat tttctcctcc tacaacttca
    10921 taatagtagc atagctctaa aaactttcca atacttcttc tatttaaagt cggatttttg
    10981 aaaattattt cacaaaaaat caaaataaag ttcgatatat tctgtccaaa tataaaaaga
    11041 gattgtgaca aaaatcttgt cacaacctct taatcaagtc ttactattat aaaaattcag
    11101 ctacacaggc caagtaacta tagggaacct actgtttcct ttttaggtcc gcgaacattc
    11161 aatgtgatct taccttttga agcacctact gttacgtggt cacctaaacg aatttctccg
    11221 ccaagcaaag cctcgctcaa tcgatcttca atttcttttt gaagtgcgcg acggattgga
    11281 cgtgcaccat attcaggatc aaatccagct ttcccgatca catcgattgc agatggtgtg
    11341 attttcactt gaatatcttg ttctttcaat cgtttgataa tcgctttgct catgatttgg
    11401 acgattgtat ggatttcatc tttactcaat gaatggaaga cgacagtctc atcgattcga
    11461 ttcaagaatt caggtcggaa agctttcttt aactcttcta agatacgttt ttgcatggct
    11521 ttgtgatctt tagtaacatc ttggacattg aatccgacat ttttttcttc tcgaatttgt
    11581 gtcgctccga tatttgaagt cataatcatg attgtatttc taaagtccac ttttctacct
    11641 ttagaatctg ttaaatgacc atcatccaat acttgcagaa gtaaattgaa aacgtctgga
    11701 tgtgctttct ccacttcatc taagagaatc actgaatatg gtttttgacg aattttttct
    11761 gtcaactgtc caccttcatc ataccctacg tatcctggag gagacccgat taatcggctt
    11821 gtactgtatt tttccataaa ttctgacata tcaacacgga tcagggcatc ttcacttcca
    11881 aacatgactt ctgaaagtgc tttggccaat tctgtttttc cgacaccagt tggtccaagg
    11941 aacatgaatg aaccaattgg acgatcagga tctttcaatc cgcttcgtgc acggcggatc
    12001 gcacgtgaaa ctgctttgac agcctcatct tgaccaacga cacgttcatg cagaagtcct
    12061 tccagttcta acaagcgttc gctttctttt ttctccaact gctgtagagg gacaccagtc
    12121 cactccgata caactgtagc aacatcttct tctgttacac gatcagaata accttgctcc
    12181 tgttttgctt caattgcaga aactttttgc agctttttac gtagtgcttt ttcttgtctg
    12241 cgtaattgag cagcattttc aaagtcttgt ttttggatcg ctgcttcctt ttcttgtact
    12301 agttcatcga tttctagttt gatcacagtt gattttgtta agtgatcggt ttgatccaaa
    12361 cggactttcg ctgctgattc atcgatcaaa tcaattgctt tatcgggtag ttgacgagaa
    12421 gtgatataac gaacagaaag attgactgct gctcgtacag cttcatctgt gatctccact
    12481 ccatggtgct cttcatatct tgtacgtaat ccttgaagaa tcacttctgc ttcttcagga
    12541 gttggctcat ctacttgaat gcgagcaaaa cgtcgctcta atgcagaatc tttttcgata
    12601 tatttttgat attcatctag ggtcgttgct ccgatcgttt gtaattctcc tcgagctaac
    12661 gccggtttca agatattcga agcatcaatt gctccttctg ctccacctgc accaattaag
    12721 gtatgcaatt catcaatgaa taagattact tgaccatcat tatagatttc gtcgatgacc
    12781 tttttcattc gatcttcaaa ttcaccgcga tatttcgtac cagcaaccaa agatcccata
    12841 tcaagcatca tcaggcgctt ttcttgcatg tcttctggca cttcacctaa aatgattttt
    12901 tgagctaacc cttcagcaat ggctgttttg cctacaccag gttcacccac cagtacaggg
    12961 ttattctttg tccgtcggct aagaatctgg ataagccgtt tcacttctct cgaacgacca
    13021 acaactgggt ccagcttgtt ttcttttgct aatttcgtca aatcacgtgc taatgaatct
    13081 agcgtaggtg ttccttgcgg tgtttgccgt ttatcttgta catttacatt tctacgacga
    13141 ttcattcctt ttccagcaga atcaccagct agccccattt tttgtttcag aacttgacgg
    13201 gcttttgaaa ggctgatacc taagttgatc atgattcgag tagccatgat actttcatct
    13261 tttaataagc tcatcaaaat atgttctgtt ccaacttttt gagaaccagt tttcttcact
    13321 tcgctgctag ctaaagcaaa aacttgtttc attcttggtg aatatggaag aaagactcct
    13381 ttagggtaag aacggatacc accataacca atcagatgtt caatttcttc ataaatttcc
    13441 gtttcattca aatccatttc acgtaatact tttccagcaa ttccattttg ctcgaccact
    13501 aaggctagta aaacatgttc tgaactaact gattgatgtt tcaaccgttt tgcttcttct
    13561 tgtgcaattt ctaatactgc ttgggctctt tcagtaaaaa gttcttccat ctaatctcac
    13621 ttcccatctt cataacttaa acgttccaga aatgctcgga gaatccgagc acgtgtatga
    13681 tcttcatatt cattgaaatt caatgtgttt tttgcaattg cactcaacat caagtttcct
    13741 tctttttttg taattatttg gtcttcataa agtttttgaa taatagcaaa agcatttttc
    13801 tcactgattg tatcatcaaa taactgattt atctgctcaa gtaattgttt tttatctgaa
    13861 atccttactt ttgcaattcg tatataacca ccaccaccac gtttgctttc tactagataa
    13921 ccacgttgga tggtaaaacg ggtattaatc acatagttga tttgtgaagg aacacagtta
    13981 aagaggtctg ccatttcaat ccttcgaatc tcgatcattt cactattttc cagaattttc
    14041 tttatatatg attcaattaa atccgaggta ttctgatgtg ccatcttatt cattcccttt
    14101 gactaatatt gaccttaatt ataacgaatt tgataataga aagaaagaag aacgcttttt
    14161 gttaaataaa tcctttagaa tcaacaaaaa aaaatacgga atatactatt ccgtatcgac
    14221 gcgcccaaga ggagtcgaac ccctaacctt ttgatccgta gtcaaacact ctatccagtt
    14281 gagctatggg cgcatattca atttaaaaaa attataaatc atttgaaaac aaaaagcaag
    14341 ataaaaaaaa tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc
    14401 tctaccaagc tgagctactt cccgtttaaa aaataaaaaa gac
//
LOCUS       DAMEEU010000070        14076 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.071, whole genome shotgun sequence.
ACCESSION   DAMEEU010000070 DAMEEU010000000
VERSION     DAMEEU010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.071"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            64..765
                     /locus_tag="PB779_002203"
     CDS             64..765
                     /locus_tag="PB779_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HDE0739713.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            762..1883
                     /locus_tag="PB779_002204"
     CDS             762..1883
                     /locus_tag="PB779_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HDE0739714.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            1898..3130
                     /gene="pepT"
                     /locus_tag="PB779_002205"
     CDS             1898..3130
                     /gene="pepT"
                     /locus_tag="PB779_002205"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HDE0739715.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            3262..4170
                     /locus_tag="PB779_002206"
     CDS             3262..4170
                     /locus_tag="PB779_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HDE0739716.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            4205..4477
                     /locus_tag="PB779_002207"
     CDS             4205..4477
                     /locus_tag="PB779_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HDE0739717.1"
                     /translation="MDVLLHNPLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            4488..5534
                     /locus_tag="PB779_002208"
     CDS             4488..5534
                     /locus_tag="PB779_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HDE0739718.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            5785..8394
                     /gene="clpB"
                     /locus_tag="PB779_002209"
     CDS             5785..8394
                     /gene="clpB"
                     /locus_tag="PB779_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HDE0739719.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQSNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(8545..9231)
                     /locus_tag="PB779_002210"
     CDS             complement(8545..9231)
                     /locus_tag="PB779_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739720.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(9209..9703)
                     /locus_tag="PB779_002211"
     CDS             complement(9209..9703)
                     /locus_tag="PB779_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HDE0739721.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            complement(9723..10943)
                     /locus_tag="PB779_002212"
     CDS             complement(9723..10943)
                     /locus_tag="PB779_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739722.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            11090..12925
                     /gene="lepA"
                     /locus_tag="PB779_002213"
     CDS             11090..12925
                     /gene="lepA"
                     /locus_tag="PB779_002213"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HDE0739723.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            13121..14032
                     /locus_tag="PB779_002214"
     CDS             13121..14032
                     /locus_tag="PB779_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739724.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGKLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEILKEINRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFKKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
BASE COUNT         4693 a         2487 c         2920 g         3976 t
ORIGIN      
        1 ttttattcct agtctcctta ttttatttgg aaaatgctat aattatctag aaggagtgaa
       61 gctatgaacc atttagattt atctcagcgc ttagccgcag tgggtgactt tgtccctgaa
      121 tccgctcgtt tagcagacat tggatcagat cacgcttact tacccgttgc attgatatta
      181 agaggaaaaa tcgaatatgc agttgctggt gaagtcgttc aaggtcctta tgaatcagca
      241 cgtaagcaag tcaaaaaaga tggattagaa gaccgtatca ccgtacgcct tgcaaatggt
      301 ctagatgcta tccagccaca agatggtatt acagctgtca cgattgcggg tatgggaggt
      361 tcactgatcc gagatatcct agaagctggc aagttgaatc aacgcttaag cggacaagaa
      421 cgtttgatcc ttcagccaaa catcggagag cgtacattac gatcttggct gcaagaaaat
      481 cagtataaaa tccaatcaga aaaaatactt gaagaaaata aaaaaatata tgaaatcatt
      541 gtagccgaaa aagaacaaaa accagttact tacaatgaaa tggagctgat gttcgggcca
      601 tttctgcttg aagagaaaag tgagatcttc aaatcaaaat ggacaagaga gcttcaacaa
      661 agaaaagcta tccgtgaaca gctcaaacaa gcagctaatc aagaggcacg tcaaaaacaa
      721 atcgagcagg aaatccaaat gattgaggag gttttaaagc catgacaatc agcggacgca
      781 ctttcatcca aaagtttgaa agctattgtc ctcagtggct agctgaagaa ggagacccag
      841 tcggactgca tatcggaaca ttggataagc caatccaacg agtaatgatg acattagacg
      901 ttcgtccaga agtggtcgaa gaagcaatca agaaaaaaat cgatttgctg attgctaaac
      961 atcctccaat ctttcgtcct gtaaaacggc tggttactga tcagccacaa gaaaaaatgt
     1021 atgcagattt gttgaaacat gatattgccg tctatgcagc acacacgaac atggatatta
     1081 tttgggatgg actgaatgac tggttttgtg aacttctcgg tattgaagtg gagagttatt
     1141 tagtaaagac tcatgagatt cattataaaa aactggccgt ttatgtacct gtggatcatg
     1201 cacagaaaat gcgtgaagta ttagctgcag ctggtgctgg tacacaaggt gattataccg
     1261 gtacaagttt tacctcgatt ggacacggtc gatttactcc ggaagctggt gcacaaccag
     1321 cgattgggaa agtagggaag acagaacaag ttcaagaggc aaaagttgag gttattttgc
     1381 cggaaactat cgaaaaacaa gtgattcaag ccatgcggtc agctcatcct tatgaggaac
     1441 ctgcttatga tcttttcgct atagatgaac cagtcgaaat gtttgggtta ggacgagtag
     1501 gtgaattgcc gcaagaaatt tctatagagg catttgtaga acaagtaaaa gaagcgttcc
     1561 aactagatgg actgagaata gtccagccaa aaaatgcaaa atcctctgtg aagcgcattg
     1621 cgatttgcgg tggaagcggt gaaaaatttt atccgcaagc aatcgcccaa agagcagatg
     1681 tctatatcac gggagatatc tattatcata cggctcatga tatgcaaagc gctgggttga
     1741 ttgcaattga tcccggtcat tatattgaat cgttatgcaa gcaacgattt atcgagaaat
     1801 ttgaatcttg gaaacaagaa gaaaattggg atattaactt tttcgtttct gaaacaaata
     1861 caaacccatt tcaatttaat taaaaggaga gaatactatg tacgaaaatc ttttgccacg
     1921 ttttttacga tatgtcaaaa cagaaacacg ctccgatgca acaagcaaaa cgactccatc
     1981 gactcagaca caagttgctt ttgcgcaaga attgaaaaaa gaattagaag agttaggctt
     2041 agctgatgtt ttctataatg aagataacgg attcgttatg ggaacattac caagcaatgt
     2101 tgatcatgaa gtgcgttcca ttggatttat ttcccacatg gatacagcag attttaatgc
     2161 agtaggagtc aatccacaaa tcattgaaaa ctatgatggc gagtctacga tcgtactaga
     2221 tgcggaagaa cgctatacat tgaatacaaa agattttcca aatttgaaaa attatgaagg
     2281 ccacacattg atcacaacag atggcagtac attactggga gcagatgaca aatcagggat
     2341 tgcggaaatc atgactgcaa tggagatctt gatcaataat ccttctatcc ctcacggtac
     2401 catcaaagtg gcttttggtc ctgatgaaga aatcggtgtc ggagcggata aattcgatgt
     2461 tgagcaattc gatgtagatt ttgcttatac agtcgatggt ggtcctttag gtgagttgca
     2521 gtatgaaacg tttagtgctg ctcaagcaaa tattacgatc caagggaaaa atgtacatcc
     2581 agggacggca aaagatacaa tgatcaatgc tctacagtta gcaatcgatt ttcataatca
     2641 gcttccagcc gatgaagttc cagaaaaaac ggaaggatac gaaggtttct tccatttgat
     2701 ggcattggat gggaatcctg aagaagcttc tatgagttat atcattcgcg atcatgatcg
     2761 tgaaaaattc gaagcacgca aagcacaaat cacacatatc caagaagagt tgaatcagcg
     2821 atttgatcaa gaacgaatca aagtagatat gtatgatcaa tattacaaca tgaaagaaat
     2881 cattgaaaaa gatatgagca tcgtggaatt agcgaaacaa gcaatgatcg agcttggtat
     2941 ctctccagtg atcgaaccag ttcgtggagg aacagatggt tcaaaaatct cttacatggg
     3001 tattccgacg ccaaatctat ttgccggagg agaaaatatg cacggacgat tcgaatttgt
     3061 ttctttacaa gtaatggaaa aagcaacaga cgtgattgta aaaattgcag aattgaacac
     3121 aaagagttaa aatcgaaaaa gaacagctta tgacaaggcg ttcgtcccaa tgatggaatg
     3181 tcatctgtct aaggctaaag ggcaggacaa tggaattggt tgtcccgccc tcttttttga
     3241 agagtaaata ggaggtaaag aatggaaaag ctgctagttt tttataacaa aagttcaggg
     3301 aaagatgagg gtgagaaatt agcacgctgg tttcaagatt atgtaaaaga aaagcagcca
     3361 gaattatatg tagaactagc tgaaactggc ccatcgattg atgatgcgga attagtcaag
     3421 aaagcagaag ccatagaagc tgatacttta gtaattatag gtggagacgg cacgattcat
     3481 catatcgtcc aagcgttcca aaaaacatta tctcaatacc atgtcggatt acttccaggt
     3541 ggaactgtca acaaccttgc acgtgttctt gagattcccc tcaaaaaaga agaagctgct
     3601 gacgtgatcc tggaaggcaa tgtacggaaa atagactatg gtcaagtcaa tgatgaagtc
     3661 attatctcta cactgacaat cggaatctta gcagatacag cagtttggat cagtcaagaa
     3721 gaaaaacagc gttacggctc gtggatcttt atcaagaagt tttttaagtt attgctgaag
     3781 aagaaaaaat atcatttgga tttagaaaca gacgaggagc attggaaagg aaaatcccaa
     3841 ctgttgacag tcacgatgtc taactccgtg ggcggtttta caaattttga cgactcagcg
     3901 accctagatg atggaaaatt tcatgtaacg atcgtacctt ccttagatat tttccgattt
     3961 attttttatt tgcctagaat catgagaggc aaattctata cgatccccgg cattacttat
     4021 ttcacagcca aacgcatgaa aatccaagcg caggaaaaat ctgtgggcac tcgaacggat
     4081 ggagacacga cagatgatct tccagttgaa ttatctgttg tatcaaaagg attaacagtt
     4141 tattcaccaa agaaagaaga aaaagcttag aaatagtagt taacagaaag ttggaagaag
     4201 agtaatggat gtattgttac acaatccttt gtggttttac cttttcattg tgaattttta
     4261 cttattttgt ctgatggggt atgataaaca tcaggctaga actagcggct ggcgtgttcc
     4321 tgagaataat ttgatatttg tcagcctgtt aggcggtggt ttgggaggat tgatctctcg
     4381 aaaagttttc catcataaaa ctcggaaaaa gaagtttact ataggattcg ctgcaggtgt
     4441 acttgttgat ttgattctca tttatttttt ccattaagga gcaggagatg tcgtctaaag
     4501 gaacgaaaac taaaatcatt ctgaatctgc ttttgctgat tgtgattttt gccattattt
     4561 attatttaat caatcaatca tttgcagata tctttgccga attgctgtct accagtgttg
     4621 ttgttttggc agcggctgtt atattaggga cagtttacca aatcgctgaa gggcgctcaa
     4681 tcaaagaaat tgctgaacct ttcgcgccga attttacaac gaaagatggg ttcttgacct
     4741 ctagctatat tgcgttttac cgaatcgttt cgtttggtac aggaacgctg atctcggaga
     4801 tttattttta taacaaaaaa ggaatgaagc tatcccaggg agcaggggtg acagcactcc
     4861 atatgattat gtacaaactg gcagtgatca cttatgcatt agctggcttg gtcatccaat
     4921 tctctctttt ttattctaat ggtccatcaa tgatctggtt tatcatcgct ggtatccttt
     4981 tgacgatcgt gattgttgcc tttttattgg cgatgtccgt cagcttgaat gttcaaatat
     5041 tttttgtcag cttatcgaat aagttattta aaagtgagcg tttgcggaaa tgggtggata
     5101 catgcaatca gcagatctac tctttaaggg aaacggtcca aaccattatc caagacagga
     5161 ctgcgctatt gcggatttat ctatggaata tgttaaaact tgtattttgg tatgtacttc
     5221 cttatttgat tctgattgaa aaccatccta aaatagattt tctactgacc atttcgttta
     5281 tcagctttgc agtagtgctt tcaggggtta ttcctacgcc tgctggtatt ggttcctttg
     5341 aatttgtcta tttgttatta ttcagaccag ttgttggaac agttgacgca gtttcttcgc
     5401 ttttactgta tcgtttcagt tcctttatct tgccatttct ctatggattt gtgtatgtga
     5461 ttgctgaacg gcgaagagtg atcaaagaag aaataataga agtaaaaaaa gagaataaag
     5521 aaaatcaagg gtaggtcttt tataagatct acccttttta tcaaatcaaa gaaaaacgtt
     5581 atggataaga taattttacg tttgtttggc tcttttttta tatacataca atcaattttg
     5641 tttttttaag atttatataa gtcgagaaaa aaagtcaaaa aactatgtgt atattttgac
     5701 caaaattgac caaagcgata taatagtttt tgtaaagatc aaagaaataa gtgatcttac
     5761 ctttaattag gagggtatac ctgtatgaat attgagaaaa tgactacgac gcttcaagaa
     5821 gcgattgctg aagctcaaca gattgcggtc actcgaaaac atcaagatat cgacattgcc
     5881 catgtatgga aaatcttttt acaatctaat cattttggtc gaaatttcta tacggatgcc
     5941 ggattggatg tcgaatcttt tgaacatgaa attgatcgtc tactggatga gtatccagtt
     6001 gtttctggtg gaaacgtcca atatggacaa aacctcagcc agaatttctt tcgattattg
     6061 aatgaagcag accaaatacg tgaaagcttc ggcgacgagt ttctttcaac ggaagtcgtt
     6121 attttagcgt tgatgaaatt aaaaaattat ccgttaactg tttatttgaa taaaaacgga
     6181 ttatctgaaa aagaattgcg taaaaacatc gaagagatga gaggaggaga aagagtgacc
     6241 tcacaaaacc aagaagaaca atacaaagca ttagaaaaat acggcgttga tttagtacag
     6301 caagtcaaaa gcggaaaaat ggatccaatc atcggtcgtg atgaagaaat ccgtgatgtc
     6361 atccgtattc tttcacgaaa aacaaaaaat aatcctgttc tgataggaga acccggtgta
     6421 gggaaaacgg caatcgttga agggcttgct caacgtatcg tacgcaaaga tgtgcctgaa
     6481 aatttaaaag ataaaacgat tttttcatta gatatgggtg cattgatcgc tggagcaaaa
     6541 ttccgtggtg aatttgaaga aagactaaaa gcagtcttga aagaagtcaa aaaaagtgat
     6601 ggacgtatcc tcttgttcat cgatgaaatc cacaatatcg taggggcagg aaaaacagaa
     6661 ggaagtatgg atgccggaaa tctgttgaaa ccaatgcttg ctcgcggtga attacatttg
     6721 atcggtgcca caactttaga tgagtaccgt caatatatgg aaaaagacaa agcgttggaa
     6781 cgtcgctttc aaaaggtatt agtcaaagaa ccaacagtgg aagatacgat cagtattctg
     6841 cgtggattaa aagaacgttt tgagatccac catggtgtta acatccatga caacgcatta
     6901 gtagcagcag ctactttatc tgaccgttat attactgatc ggttcttacc ggacaaagca
     6961 atcgatttga tcgatgaagc cagtgcaacg attcgggtag aaatgaactc tatgccaacg
     7021 gaattagatc aagttactag acgtttgatg cagttggaaa tcgaagaagc tgcactgaaa
     7081 aaagaatcag atgatgcaag taaaaaacgc ttgaaaaatt tgcaagaaga attagctgaa
     7141 cttcgtgaag aagcaaatgc gatgaagatg cagtgggaaa cagaaaaaga agaagtcaat
     7201 tctgtttcag caaaacgtgc tgaaatcgat aaagcaaaac acgaattaga agatgcagaa
     7261 aataactatg atttagaacg cgctgctgta ttgcgtcatg gtacgatacc tcaattagaa
     7321 aaagaattga aggaattaga agctaaagca aaagacagcg agattaagat ggttcaagag
     7381 tccgttaccg aaaatgagat tgctcaagtc gttggcagat taacgggtat ccccgtaacg
     7441 aaacttgtag aaggtgaacg agaaaaacta attaaattga atgaaacact tcataaacga
     7501 gtgattggtc aagatgaagc agttgatgcg gtcagtgacg cggtaattcg ttcacgggct
     7561 ggattgcaag acccaaatcg tcctctaggt tctttccttt tcctaggacc aactggtgtc
     7621 ggaaaaaccg aattagcgaa agcgttagct gagaacttgt ttgactcaga agatcatatg
     7681 gtacggatcg atatgagtga atatatggaa aaacatgctg tgtctcgtct agtcggagct
     7741 cctccaggct atgtaggtta cgaagaaggt ggtcaattaa cggaagctgt cagacgaaat
     7801 ccttatacaa tcgtcttgtt ggatgaaatc gaaaaagcgc atcccgatgt cttcaatatc
     7861 ttgttacaag tcctagatga cggacgcttg actgattcaa aagggcgagt agtagatttc
     7921 aaaaatacgg ttctgatcat gaccagcaat atcggttcac agttactgct ggaaggcgtg
     7981 actgctgatg gaacgattcc agaagcagtg gctgaacaag tcaacacgct attacgtgga
     8041 aacttcaaac cagaattctt gaaccgaatc gacgacacga ttttatttac accattgagc
     8101 ctagacaacg tgaaaggaat cgttgacaaa atggtggcgc aattggcaca acgtctggaa
     8161 catcaagaaa tcctgctgac aatcagtgat gaagccaaaa cgtggattgc tgaaaatgct
     8221 tatgaaccag catatggtgc aagaccattg aaacgattta tcactaagga agtagaaaca
     8281 ccactagcta aagaaatcgt tgcaggacat gttatgccta aatcaaaagt aacgattact
     8341 ttacttgatg gacaacttca tttcaaaaca gaagagctag aagaaatcgt ctaatcttcc
     8401 attgagacta taaaagaaaa aaggggtctg acacaactag tgtcagacct ccttttttca
     8461 aataaacagt gttccagaag tagtttcttc gaaaaataag ccgaaatttc ttgaagctgc
     8521 ccgcttctgt cacaacctct tttattaggt atttttcact ttttctaatt tataactttc
     8581 aaagtaacgc tcatcttttt tactttgaga ccatgcaaac aatcccatta aggcagcacc
     8641 tatcgtattt gtcagcaagt cgcccatcgt atccatcaat gctgctcgtc cgacaaacag
     8701 tgtgccatca gaagcagcaa aacgttgaag attcatgcct aagaactggt cgcataagaa
     8761 ttcccagaac tcccaaaaca cgccgcaaag tccagcaaac gcaaagccga ataagaggaa
     8821 caaccaagga ctggtttttg atatctcagc atctttcatc aagtaaccaa tcaatccata
     8881 gccaagagct gtcaggacca ttggactcac cgcatgtaag attttgtccc aaaaagagat
     8941 gatactgatc aaatgcatcc ctgtgcctaa aaagacagag atgaacaaga aaaaccagta
     9001 aaacaaaacg attgctgctg gtattttaag tttgaaaact ttcaaaatga cttgtggcat
     9061 gaaaatcaat gcaatcccta ataaagattc cacgataaat gtgattcctt gagaagtcga
     9121 atatttttgt gtgataaatt cataaaaatt atagcagaca acgaatacac caaaagcaag
     9181 taaagctatt tgcacctttt tgatttcttt aatcactgaa agtccctcca tctaaaaatc
     9241 tttttacttc tgaaagcaac tcaatttctg aagaaaccac ttttccgttc aatttgatca
     9301 aacctattgt atataagttc aggtagtgaa attgattttc agctgtttct tgtagtgcag
     9361 cgattttttt cgggtgggtt ccgccttgct gtcgagtatc agtatataag ccgatcactg
     9421 ggatgccttt cgcataagcc acaccgattt ccgatgctac cccggcatcg atcgtcagcc
     9481 catctagtaa agcaatcatt aaatcactag ccaacacttt ttctgtgtca gcaagagcaa
     9541 tcattcgact gtctgcataa gcagttttgt cattgattgc ttcattttct tgaggaagat
     9601 agatcgaaag ctcagaagag agctctctga tttctttaac taactgttgg ttatataaca
     9661 aatcactttt agcaaacatt ggtgcggcaa aataaatttt catctaaaca tcatcctttt
     9721 tatcaaaaat aatcgctaaa gtaagcttcc atgtttggaa tgatacgctc tagtgacttc
     9781 agtgtttctt catctgtttc taaccgttcg attcttgcca aataagaagc acggcgataa
     9841 ttcatcatca agcaagtcaa tgtttggata tccagtcgaa cggattttcc tataggttca
     9901 tttaagacac ggacttgtcc ctgttcatcc catgttaaag cgaagacacc attattccaa
     9961 ggagcgacag gatcttcaat gatgaaatga aaagcatcag ctgttccaac aaacggaaac
    10021 cgttgaagga attcttttac atcaacgatc cgagccataa aatatggttc gatctgctct
    10081 ttgatctgac tatcttcaat caaaaatgct aaaggctcat ttttataaat atctccatgt
    10141 acccagtaga tcatggaaaa atgtgcggaa ataaagttcc ataagccatt tcgagcttct
    10201 tgatcaagat agaacatttc ttttacgtga aatatttctt cagctaccca gtagaacaga
    10261 acacctcttg gttcatggtt gctatcgtag tagacagcgg ctgtgcgctc atcttcattt
    10321 tcgaaacgcc aatactcttc ccaatgaaaa tcactgcgga ataaagcacc atggttttgt
    10381 tgggcaaatt tgtcataaac ggaaaatacg tctggatgat caactggtaa tcgctcaacc
    10441 ataccactta ctgggatttg tttaggtagc tgtgtatctc tgattttaaa ggaaagttta
    10501 tcagacatga tttcccatcc tttacgccga tagtagggga tactgtaagg atacaaataa
    10561 gagatccatt gcttattctt gcgcatatta tccaatgcaa cgataattag atcttgcatc
    10621 aatccatggt tagcatattc tggataagtt ccaactccag tcacaccacc cattttataa
    10681 cgtgcaccgt gaatattgac ttcacaagga tagatagcga tttgagagat cagtttattt
    10741 tcgtggaacc atccgaacac tttcgatact tccaaaatcg gttttttgga acggataaaa
    10801 gctcgtttat tctcaaaccc gctttcctcg atgtctgctt cagtcacttg gaacacatag
    10861 gaaagcaatt cattgaattg atcgatatgt tcttgagtga ccggttttaa ttcaagattt
    10921 tctctaaaat ctttttgatc cattttttca tctccattta ttagcttgat aacagtatag
    10981 caaaattcta caaaaaaaac ttctatagct gactaattaa aaactcttta aattactgct
    11041 tttcgttggt ataatggaaa gtgctgatta tatgaaaaga ggagacgcta tggatataaa
    11101 gaaaatgaaa gaacgccaag agcagattcg taatttttcg atcatcgctc atatcgacca
    11161 tgggaaatct acattggccg atcgtatttt agaaatgacg cacactgtga cgtctcgcga
    11221 aatgcaagat cagctgttag actcgatgga tttggaacgt gaacgtggaa tcacgattaa
    11281 attaaatgct gtagaactca attacacagc gaaaaatgga gaaacatata tctttcactt
    11341 gattgacacc ccagggcacg tcgacttcac ctatgaagtc tctcgaagcc ttgctgcctg
    11401 tgagggtgcc gttttagtgg tcgatgcagc acaaggaatc gaagcacaaa cattggccaa
    11461 tgtttattta gcgttagaca atgatttgga gatcctgcca gtcatcaata aaatcgacct
    11521 acccgcagca gatcccgaac gtgtccgtca agaaatcgaa gacgtaatcg gaatcgatgc
    11581 tagtgaagct gtattagcca gtgccaaatc agggattggg attgaagata ttctcgagca
    11641 gatcgtggaa tatgttcctg caccaagtgg agacttagat gcaccgctaa aagctttgat
    11701 ctttgactct atttatgata gttaccgcgg tgttgttcta aatgtccgga tcacggacgg
    11761 tatggtcaaa cccggagaca aaatcaaact gatgagtaat ggcaaaacat ttgatgttac
    11821 agaggtcggg gtcttctcgc caaaagcagt tgctagagac tttttgatgg tcggtgatgt
    11881 cggttatatc acagcaagta tcaaaactgt ccaagataca cgagtagggg atacagtaac
    11941 gttagcagac aatcctgccg ctgaagcttt accaggttac cgaaaaatga atccgatggt
    12001 ttattgtggt ctttatccaa ttgatacttc tcgttacaac gatttgcggg aagctttaga
    12061 aaaactgcaa ttgaatgatg ctgctttaca attcgaacca gaaacctctc aagcattagg
    12121 ttttgggttc cgctgtggat tcctcggact tcttcatatg gatgtcgtcc aagaacgctt
    12181 ggaacgggaa ttcaatctag aattgatcac gactgcacca tccgttattt accatgttaa
    12241 taaaacggat ggtacgactg ctacagtaga taacccggca gattttcctg aacctgtaac
    12301 gattcaggat gtagaagaac cattcgtcaa agcacagatc atggtcccaa atgattttgt
    12361 cggtgcagta atggaacttt ctcaacgaaa acggggagaa ttcattacga tggattattt
    12421 agatgattac cgagtaaatg tcgtctataa tattccgctt tctgaaattg tctttgactt
    12481 tttcgacaaa ttgaaatcaa gcacgaaagg ctatgcctca ttggattatg aaatgtctgg
    12541 ttatcaaaaa agcaagttag tgaagatgga catcttgctg aatggagaaa aagtcgatgc
    12601 attaagcttt atcgttcacc gagactttgc ctatgaacgt ggaaaagcaa tcgttgaaaa
    12661 actgaaaaaa ctaatcccac gccaacaatt tgaggtgcca atccaagcag ctattggaca
    12721 aaaaatcgtt gcccgttcag acatcaaagc cttgcgtaaa aacgtcttgg ctaaatgtta
    12781 tggtggagat gtttctcgta aacgtaaact cttagagaaa caaaaagaag ggaagaagcg
    12841 gatgaaacaa atcggctccg tcgaagttcc gcaagaagcc ttcatggccg ttctgaaaat
    12901 ggatgagcaa gatagtgtga aataacttat aatcaatcga aaaacctatt aaataaacct
    12961 ttttgagtag atgcaacact gaggattatc tgtataaaag attttaaact gtcatttggt
    13021 tatcacggcg atactaaaat taacaaaatt ggaatatttt tcttgaagat ttttagctgt
    13081 cagtatatga tgaaagcatc tcataggagg tgcttttttc atggttgata attcaagtgg
    13141 aagggttctt aaatctctaa gaaaagagaa aaaactatct caaaaaaagt tagctgattt
    13201 agcaggtatt tcacaaagta ctttagttaa atatgaaaaa gggtcaagaa aaatccctaa
    13261 agacgtagat aatactctaa gcaagattct gaatatagaa actctaataa aagatgagga
    13321 agataagatt gagattctca tcggtaaact aattgcatac agagatatga ataagttact
    13381 taacaaagag ttagctgata atataggaat tagtgaagta ttactcagtt atgtgttaaa
    13441 tagaaagaga aatccgtcaa aagaaatgca aaaaaaaatc gatatttttc tattaagtaa
    13501 tgaaaaagaa attttgaagg agattaatcg tgatagtgag atatttagtt tatcaaaaga
    13561 cgataaaatt gttatgggaa aaagaatacg agaagtccga aagaaccggg aagagacgct
    13621 tgaaaaattt ggtaaaaact ttaccatcta tacaggcaaa aatgttataa gtagatggga
    13681 aaaaggtatt aatattccag atattgaaaa actaatgaat attgcctatc ttggtaaggt
    13741 cactgttcct taccttatgt acggagaaga ttataagaat atacttccaa aagatgaaag
    13801 agttagcgat tttaaaaaga taaattcttt tagtatggga ttaaggatga ggaaaattag
    13861 gaaagattat tatctagaaa gggaggagtt tggaaagctt ttttctcctt caatttcaaa
    13921 atggtccata gataggtatg agaatggtag agatataccc aatactaatc gaattatcca
    13981 atatgcttat ataggaaatc tttctttaga atttttgatt tacgggatat aaaaatagtt
    14041 tacgtcgata cttattaagt tatcgacgtt ttttat
//
LOCUS       DAMEEU010000071        14072 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.072, whole genome shotgun sequence.
ACCESSION   DAMEEU010000071 DAMEEU010000000
VERSION     DAMEEU010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14072
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.072"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(143..1345)
                     /locus_tag="PB779_002215"
     CDS             complement(143..1345)
                     /locus_tag="PB779_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0739725.1"
                     /translation="MKTKYPCVYQDKNGRFSYLVELGTDQVTGKRIQKKGTKDSLGKR
                     FSSAREAHKEVMRIKNEYMVVNGFANYDLTYKEFMEQSYVPHYKASVQKSTWSSRECG
                     LIQITEFFGDKKLREINVRDCENYRIWLLNDSGYSQAYSSLMYGMFRKSLDYAVTLQF
                     LNENISKRTKAIPKGKSIVPYWTKEEFEEVLAKIYKDDFYEHMCFLMIWLYYMTGVRV
                     SEGLALNWNDVDFKRKKLRVHHTLEMTNQKDFIRKPYTKTESGLRIISLDDDTIEVLK
                     KWKVIQKNHGVEQFILSYTDLPLYRSTVQRIIQRYAKLAKVPLIQGKGLRHSHVSYLI
                     NEFNADILVVSQRLGHSSPEITLKHYAHLWSRNDEGIAEQMTGNIKFTCATKSKVANF
                     NGNQAVKI"
     gene            complement(1348..1542)
                     /locus_tag="PB779_002216"
     CDS             complement(1348..1542)
                     /locus_tag="PB779_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HDE0739726.1"
                     /translation="MKNTICRKDLEALGFKTHQATTIIRQAKTRMVNQGYPYYNNKRV
                     GVVPRQVIEEIIGVPLSQEE"
     gene            complement(1589..2437)
                     /locus_tag="PB779_002217"
     CDS             complement(1589..2437)
                     /locus_tag="PB779_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rep protein"
                     /protein_id="HDE0739727.1"
                     /translation="MQAYNQKIIETPTYIEIYDYEAIITPKRKTIENEVNLERKQKLA
                     WIYENDITLEKRKNYDELSAQGQYDSLKRKQKHYQSMRFEIARLVDTNFDNQTKFLTL
                     TFKENIQDIEYANNEFKKFIKRLNYDLYKTKKANLKYLATWEKQQRGAIHYHIILFDF
                     PFISFNRLTTIWGQGFVKINKIDVDSIENRGRYISKYFDKELELKEHKKKAFFKSRNL
                     KLPTVTKKMVKKPYDSTNQDILYTSEYIVRRPFFYNALALNELGSPEQVMDFQESTVH
                     YTKIKK"
     gene            complement(2642..2992)
                     /locus_tag="PB779_002218"
     CDS             complement(2642..2992)
                     /locus_tag="PB779_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002401157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739728.1"
                     /translation="MPIKITDLSLPKETLEKEYQVVNVTRWQKEGEILGWSYECILPK
                     LRYEKISVKVKSEHPVITPEELTQQGLAIITFTNLVIVPWGRSNGQFVSYGLSATADT
                     ATLIPRKQGTTTQN"
     gene            3587..4033
                     /locus_tag="PB779_002219"
     CDS             3587..4033
                     /locus_tag="PB779_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HDE0739729.1"
                     /translation="MKDYVVQITKEVLEESKTLNKLSSKAKEEAVTILSSGIIDYIEM
                     SGEIKYGEKDRIAKMVKESIKTFDVKQDLTFNDSYLIGKLINILGTDEDTELFLSSLS
                     MIFTDKHFSTRFGGEELVEIFQSMRPALIKLYREKTPDEFYDWFEK"
     gene            4657..5649
                     /locus_tag="PB779_002220"
     CDS             4657..5649
                     /locus_tag="PB779_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HDE0739730.1"
                     /translation="MYWEEIELEKTLGPGGEIRAVQRDKKNISKWEKLKKQLRRDKWM
                     YLLLLPGIIMTFIFKYVPMYGAVIAFKDYNPMLGILESPWVGLDHFREFISSPNFTLL
                     LSNTLKISIYGLLLGFFPPIILALSLNQIINKKIKQKIQLILYAPNFISVVIIVGMLF
                     LFLSANGPINGLVEKVTGQPIMFMSNPAYFRTIYILSGIWQGIGWSSILYTATLAGVS
                     TDLYEAANIDGANILQKIWHIDLPALRPVMVISFILAAGGIMNVGYEKAYLMQTSMNI
                     PASEIISTYVYKVGLQSGDYAYSAAVGLFNMIINVVLLLIVNNITKRLNDGQGL"
     gene            5665..6549
                     /locus_tag="PB779_002221"
     CDS             5665..6549
                     /locus_tag="PB779_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HDE0739731.1"
                     /translation="MNSALSKIDRQILWLNRVIVTFLVVITIVPLIYVLVASFMDPAT
                     LINKGISFNPKDWTIQGYQRVFADDSILRGFVNSLFYSFSFSLLTVFITMITAYPLSR
                     PNLAGKKIIMTFFVITMFVGGGLIPTYLLVKNLGMLDSVWAIIVPGAINVWNIILART
                     YFSALPKELSEAATIDGANDLQILFKVMLPLAKPIMFVLFLYAFVGQWNSYFDAMIYI
                     KDPDLQPLQLVLRNILIQNQPSQDMVGANTAMAEMKQIAELIKYATIVISSLPLIIMY
                     PFFQKYFDKGVLVGSVKG"
     gene            6598..8205
                     /locus_tag="PB779_002222"
     CDS             6598..8205
                     /locus_tag="PB779_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0739732.1"
                     /translation="MKAKWMLPIVFTSVLILGACGGSKEKSKSSPDYELENVSFPLKE
                     KVSLKMMSQSAPLAPNDPNDKLIFQRLEEETNLHIDWTNYSSDFAEKRNLDIASGDLP
                     DAIFNAAAGDYDLLNWAESGVIVPIEDLIEDYMPNLKKIFDENPEYRQMSTAPDGHIY
                     SMPWIEELGEGKESIHTVNGMAWINKEWLDNLGLEMPQTTDQLMTVLEAFKTQDPNGN
                     GEADEIPFSFINNGGNEDLKFLMGAFGLGDNDDHLVVDNDGQVQFTANKEGYKEAIKY
                     FNEMNNKGLIDKEAFEQDWNTYVAKGKEHKYGVYFTWDKANITGADDSYDVLPVLAGP
                     DGTKHVTRTNGMGFSRDRFVITSANKNLELTARWIDKMYEPLQSVQNNWGTYGDEAQA
                     NIFELKDGMLKHLPLEGTAPGELRQKTEAGGPLAVLDSYYGTVTTMPDDAKWRLDLMH
                     DTYLPYITEDNIYPRVFLEKEETDRLAKIETDMWDYIYRKRAEWITGGKIDEEWEEYL
                     AELERVGLEEWIQIKQTGYDNFLKGAQ"
     gene            8206..9690
                     /locus_tag="PB779_002223"
     CDS             8206..9690
                     /locus_tag="PB779_002223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016621147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HDE0739733.1"
                     /translation="MLVEETAILDKANRFIEMMRGKVNPQYRQNYHFSAPIGWINDPN
                     GFIYYKGHYHLFYQYYPYDSRWGPMHWGHARSSDLVHWEDLPVALAPDQPYDSGGCFS
                     GSAIERDGKLYLFYTGCQEIDGISHQHQCLAVSEDGIHFSKYSGNPVVAEKQLGENGL
                     IQEFRDPKVIVHNDGYYMVVATKSTQSTGRIVMFQSSDLYTWHFYSVLLEGTSEQGIM
                     WECPDLFHLDGRDVLIMSPIQIKKNGLEYHNISSTMACIGEVNWETGQMIVDNFHEMD
                     FGMDFYAPQTTRDPNGGRVMIAWMQMWDRTLPTHELGHLWAGSMSLPRELRVKKNRLV
                     QKPISTVYSHLVYQQGSENIAVTDTSVVFRNALSDSSYLHLVADLEKAEVFTIELLRS
                     KTDCLKLAYDTATQVFELDRQKLGRELTGAEEDPLNVRKVEVPLIDNQLVLEIFRDTS
                     SIEVFINGLEVMTATFYELEKARDILFHSIGESRIQAFETASVK"
     gene            9867..10859
                     /locus_tag="PB779_002224"
     CDS             9867..10859
                     /locus_tag="PB779_002224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005230454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0739734.1"
                     /translation="MKATMKDVAKLAGVGVGTVSRVLNNGSVKASTREKVEAAMTELN
                     YQPDFYARGLKMKHTNTVALILPTVWHPFFGEFAYHVETALERQNYKLYLCNSSGNSE
                     KEQEYIQMVSQNKVDGIIGITYSDIDEYISSNLPFVSIDRYFTEEVIYVTADNAAGGR
                     LAANELYRRGCQNVAYIGGYQETPNETKSRRKYFEIECRQLGISYKALDMLEPLDHLS
                     ERVTNFLLENPDIDGIFTINDPMALAVIDMLEKIGKNVPEDVQVIGFDGQKMTEGDPY
                     LVSTIAQPTKQMAEVAVAKLIAVINGETVEKRTVLPIEFGEGDTTKPLVRNDFA"
     gene            10911..11780
                     /locus_tag="PB779_002225"
     CDS             10911..11780
                     /locus_tag="PB779_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDE0739735.1"
                     /translation="MLYGGIEAGGTKFVCGIGNEQLQVIERKSFPTTTPEETMEQVFD
                     FFDKYKGNIASIGVGAFGPIDIQIESRTYGYITNTPKLAWQNYHFVGALENALSVPIY
                     WTTDVNAACYGEYMAGYGKGKNSVLYYTVGTGVGGGAVVDGKIVAGFSHPEMGHMLLQ
                     RHNEDQFEGICPFHHDCLEGLASGPAIEKRFGRKAQTISFDHPYWTIEADYLAQCVYN
                     TTLLYAPEVIILGGGVMKQPQLLELIRQSFKEKMGSYVDTPTLEEYLLTPRLADNAGL
                     IGCLALAIKKLNH"
     gene            complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="PB779_002226"
     CDS             complement(12200..13765)
                     /gene="guaA"
                     /locus_tag="PB779_002226"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HDE0739736.1"
                     /translation="MSSPTRFDEEPKIIVLDYGSQYNQLITRRIREFGVFSELMSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDEKAFGIDEKIFDLGIPVLGICYGMQLITYKLGGK
                     VKPAKNREYGKAELEITSAEAALFQNTPEKQTVWMSHGDLVTQAPTDFDVVATSKDCP
                     IASIQNAERKMYGIQFHAEVRHSEYGNDLLRHFTLDVCQCTGDWTMDNFIDMEIAKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTCIFVDHVLLRKGEAEQVMESLGGK
                     FGLNIIKVDAKERFLSKLAGVSDPEEKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFKLIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGELTEEKLEIVRESDAILREEIANAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(13820..>14072)
                     /locus_tag="PB779_002227"
     CDS             complement(13820..>14072)
                     /locus_tag="PB779_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0739737.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVSHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         4307 a         2384 c         2908 g         4473 t
ORIGIN      
        1 ttgaaaaacg ttgatttatc ggcattcccc atccatatta tatttacgtc ttattcccac
       61 tcaatatgag tagcctcgta aagaagctat tatatcagtg ctttttcagc ctattcctca
      121 ttttggtagg gaaatggtag ggttagattt ttactgcttg atttccatta aagtttgcaa
      181 ctttagattt tgttgcacag gtaaatttaa tgtttcctgt catttgttct gcaattcctt
      241 catcattacg gctccataga tgagcgtagt gctttaaagt gatttcaggg ctagaatggc
      301 ctaaccgttg cgacacgacc agaatgtctg cgttaaactc attgattagg tagctaacat
      361 gagaatgacg taatcctttt ccttgtatta ggggtacctt agctagtttg gcataacgct
      421 gaataattcg ttgaacagtt gaacgataga gtgggaggtc agtgtagcta agaataaatt
      481 gttctacacc atgatttttt tgaataactt tccacttttt tagcacttca attgtatcat
      541 cgtccagaga aatgatccgc aagccgcttt cagtttttgt gtaaggtttc cgaataaaat
      601 ctttttgatt tgtcatttcc aaggtgtgat gaaccctcaa ctttttacgt ttgaagtcca
      661 cgtcattcca attaagtgct aatccttcgc ttacacgaac accagtcatg taatatagcc
      721 agatcattaa aaaacacata tgttcgtaga aatcatcttt ataaattttt gccaaaactt
      781 cttcaaattc ttcttttgtc cagtaaggaa cgattgattt tccttttgga attgcttttg
      841 ttcttttgga aatattctca ttcagaaatt gcagggtgac cgcatagtct aatgatttac
      901 gaaacatacc gtacataagt gaactgtatg cttgtgagta tccgctatcg ttcaataacc
      961 aaattcgata attttcacaa tctcgcacat tgatttcacg aagcttctta tcaccgaaaa
     1021 attcagtaat ctgaatcaat ccacactcac gagaactcca agtacttttt tgtacgctag
     1081 ctttgtagtg tggaacgtaa gactgctcca taaattcttt gtaagttaaa tcataattcg
     1141 caaatccatt tacaaccatg tattcatttt ttatacgcat gacttctttg tgtgcttcac
     1201 gagctgatga gaatcgtttt cctagagaat cttttgttcc tttcttctgg atcctctttc
     1261 cagtcacttg atctgttcct aactcaacta gataagaaaa gcgaccattt ttatcttgat
     1321 acacacaagg gtattttgtt ttcatagtta ttcctcctgt gaaagaggaa cacctataat
     1381 ttcttcaatt acttgtcggg gtactacccc aactctttta ttattataat atggatatcc
     1441 ctgatttacc attcttgttt ttgcttgtcg gattattgtg gtagcttgat gtgttttaaa
     1501 tcctagagcc tctaaatctt ttcgacaaat tgtatttttc attgtataaa ctcactttca
     1561 aagaaaacac tatcattggg taatagtgtt atttctttat ttttgtataa tgaacggtac
     1621 tttcttgaaa atccatcact tgttcaggac ttcccaactc atttaaagct aaagcattgt
     1681 aaaaaaatgg acgtctaact atatattcgc ttgtatatag tatatcttga ttcgtggaat
     1741 catagggttt ctttaccatc tttttggtga cagttggtag tttgagattc cgggacttga
     1801 aaaaagcttt tttcttatgc tctttcaatt ccagctcttt atcgaaatat ttgctgatat
     1861 agcgcccgcg attttcgata ctgtctacat cgatcttgtt gatcttaacg aaaccctgac
     1921 cccaaatcgt agttaaccgg ttaaatgaga taaaggggaa atcaaacaag ataatatggt
     1981 agtggattgc accgcgttgc tgcttttccc acgtggcgag atactttaaa tttgcttttt
     2041 tagttttata gaggtcataa ttcagtcgtt tgataaattt tttaaattca ttatttgcat
     2101 actcaatgtc ttgaatgttt tctttgaaag tgagagttaa aaatttcgtt tgattgtcaa
     2161 aattcgtgtc tacaaggcgg gcaatctcaa atcgcatact ttgataatgt ttctgtttgc
     2221 gttttaaact gtcatattgt ccttgagcgg ataattcatc atagtttttt cttttttcaa
     2281 gagtaatatc attttcataa atccaagcta atttttgttt tcgttccaga tttacttcgt
     2341 tttcgatcgt tttacgtttg ggagtaatga ttgcttcata atcataaatt tcaatatacg
     2401 tgggagtttc aatgattttc tgattataag cttgcaaaaa tcatcactcc ttgttgcgta
     2461 ttcgattgtc aaagaaccag tcattttctc ctgatgttga tctataaatc aagttaaggg
     2521 ggaaggcctg cgtagcagcc cttctagcct atggggtgtt gggcggtctt aacggacaga
     2581 aacggctctg tgggcgctgc cccgccgttt cgtcctaacc acccaacact ccatagtata
     2641 gttagttttg tgtagtggta ccttgttttc tgggaatcaa agttgccgta tcagcggttg
     2701 ccgataaccc ataactgaca aattgtccat tcgagcgtcc ccaaggtaca atcaccaaat
     2761 tggtaaatgt aattatggct aaaccttgtt gggtaagttc ttccggcgtg atcacaggat
     2821 gttcagattt gactttgaca ctgatttttt cgtagcgaag ttttggtagg atacattcgt
     2881 agctccaacc tagaatttcg ccctcctttt gccagcgagt gacattgacg acttggtatt
     2941 ctttttcgag tgtttctttt ggtaaactga gatcggtaat ttttattggc atcacaattc
     3001 tcctttttta tacgaaagtt tatacgattt gattaaaaaa tatagatggc catctacgac
     3061 ttgtattata tacgagaact tatacgtagt caagagattt tctaaaaaaa tatatacgat
     3121 tttttatacg agtgttataa tgaaaaaaat gataaggagg aatttgaata tgtttggttt
     3181 agtacaacct aataaagtga aggtgggcca acgaatcaaa gaaataaaag acggaatgtc
     3241 tctctctttt acagaattag ggaatcgatt aggtttaaaa aagccgacga tcagttccta
     3301 cgttcaaggc tatgcgttgg ctcctaagag tgtgatcaac caattatcta gtatcagcgg
     3361 aaaacctgtc ggctggtttt attttgggca tgtggaagaa tatatccgag agtatttgtt
     3421 tctcattggt cagaaaaaaa tagtggacga ttatcctgaa atcattgaga aaataaagca
     3481 agaattttat acgggcgagt tcaaaaatcc tgcttgggag aatgagctag gctatccttt
     3541 ggaggaattt atccaagaat gttttgtaga atattcgagt gaaatcatga aggactatgt
     3601 cgtacagatt acgaaagagg tacttgaaga atccaaaacg ctaaacaaac tatcatcaaa
     3661 agcaaaagaa gaagctgtca cgattctttc atctgggatc attgactata tcgagatgag
     3721 tggtgagatc aagtatggag agaaagatcg cattgcgaaa atggtgaaag aatcaataaa
     3781 aacctttgat gtgaaacaag acctgacatt taatgattcc tatttgattg gaaagttgat
     3841 caatattctt ggtacagatg aagatacgga gctgtttctt tcttctttat caatgatatt
     3901 tactgataag catttttcca ctcgatttgg tggggaagaa ttagtcgaaa tatttcaatc
     3961 gatgcgacca gcgttaatca aactctatcg ggagaaaaca ccagatgaat tttatgattg
     4021 gtttgagaag taaaataaga aaagtggctt agattacaag ttggtgaaaa aatttttttc
     4081 agcataacat cagtaatcta taaaggggtt gttgattata ctgtagaagt taagtactca
     4141 agagattttt tgtacgtaaa caaagcaaaa aagggtgcag tttcactaga aaatgtactc
     4201 ttttttgtga tttttcttag ttatagagtt tttttgaaac tttaaaaatg agaaaacata
     4261 ttgattttaa agagtgtaga catagcttct tttgctaaat agattaaact tactggtgag
     4321 tggtcttgaa catactttta aatcacattt tactgagttt tattggattt tataattcat
     4381 tggaaacctc gtacttaatc tgtttttatc tatcgactag aatctgtata tattccagct
     4441 atcaatgagg ccgcagaaaa gggtgcttaa aaataatctg ttgtttaaaa tattattatc
     4501 agaatactta gatacaaaat tctggcacaa agtaaaaaaa atattgactt aaaaaaatgg
     4561 atatggtaat ctataaacga aaatagtggt aacgtttcca aaatgcatct tcgttaaatt
     4621 tttatttttt taaacgaaaa tggaaacgtt tctaaaatgt attgggagga gattgaattg
     4681 gaaaagacat tgggaccagg tggtgagata agggcggtac aacgggataa aaaaaatatt
     4741 tcgaagtggg aaaaattaaa gaaacagttg cggcgtgata agtggatgta cttgttgctc
     4801 ttaccaggta tcatcatgac gtttatcttt aagtatgtgc caatgtacgg tgctgtgatt
     4861 gcatttaaag actataatcc tatgctagga attttggaaa gtccttgggt aggactagat
     4921 cactttaggg aatttatcag ttcaccaaat tttacgcttt tgctgagcaa cacattaaaa
     4981 attagtattt atggtttatt gttaggtttt tttccaccaa ttattttagc actgagcttg
     5041 aatcaaatta tcaataaaaa aataaaacag aaaatccagt tgattctata tgcgccgaat
     5101 tttatctcag tagttattat tgtggggatg ctgtttttgt tcctatccgc aaatggacct
     5161 attaatgggt tagtagaaaa ggttacgggg caaccaatta tgttcatgtc taatccagct
     5221 tatttcagaa cgatttatat tttatcggga atttggcaag gaatcggctg gtcatccatt
     5281 ctttacaccg caacgctggc gggagtcagt accgatttat atgaggcagc aaatatcgat
     5341 ggggcaaata ttttacaaaa gatttggcat atcgatttgc ctgcattgag gcctgtgatg
     5401 gtgatcagct tcatcttggc cgccggcggt attatgaatg taggatatga aaaagcctac
     5461 ttgatgcaaa cttcaatgaa catccctgcc tcagaaatca tttccactta tgtatacaaa
     5521 gtcggcttgc aatcaggtga ttatgcctac tctgctgctg ttggtctgtt caatatgatt
     5581 attaatgtcg ttttattact gattgtcaac aatataacca agcggctaaa cgatggtcaa
     5641 ggcttgtaat gaaaggagaa aattatgaat agtgctttat caaaaatcga ccgtcaaatc
     5701 ttatggttga atcgagtgat tgtaactttt ttagtcgtca tcaccattgt tccgctgatt
     5761 tatgtactgg tagcttcttt tatggaccca gctactttga tcaataaagg tataagcttc
     5821 aatccgaaag attggacaat acagggatat caacgggtat ttgcagatga ttccatttta
     5881 cgcggttttg taaattcgtt gttttactct tttagcttca gcttattgac tgtatttatt
     5941 acgatgatca ctgcgtatcc tttgtctcga cctaacttgg cggggaaaaa gattattatg
     6001 actttttttg tcattacaat gttcgtgggt ggtggcttga tacctaccta tttattggta
     6061 aagaacttgg gcatgttaga tagtgtatgg gcgattatcg taccaggtgc tataaatgtg
     6121 tggaatatta tcttagcccg tacctatttt agtgctttgc caaaagaact ttctgaagct
     6181 gctactatcg atggcgccaa tgacttgcaa atactgttca aagtcatgct tccattagcg
     6241 aaaccaatta tgttcgtatt gtttttatat gcctttgttg ggcaatggaa ctcatacttt
     6301 gatgccatga tttacatcaa agatcccgac ttacagccgt tgcaactcgt attaagaaat
     6361 attttgatcc aaaaccaacc ttcacaagac atggtgggag ccaatactgc catggcagaa
     6421 atgaaacaaa ttgctgagtt gatcaaatac gcaacgatcg tcatttctag tctgccatta
     6481 atcataatgt atcctttctt ccaaaaatat tttgataaag gtgttttagt tggttctgtt
     6541 aaagggtaag tattgttcac tatttgtatg aataaaaatt ataaaggaga ttttaagatg
     6601 aaagcaaaat ggatgctgcc aatcgttttt acttccgtac taattttggg ggcttgtgga
     6661 ggctcaaaag aaaagagtaa atcaagccct gattatgaac tagaaaatgt ctcttttcca
     6721 ttgaaagaaa aagtatcttt aaaaatgatg tctcaaagtg cccctttggc tcccaatgat
     6781 cctaatgaca aattgatttt ccaacgatta gaagaagaga ccaatctcca tattgattgg
     6841 acaaactaca gtagtgattt tgccgaaaaa agaaatttgg atatcgctag tggtgattta
     6901 ccagatgcca tcttcaacgc cgctgcaggt gactatgatt tattaaactg ggcggaaagt
     6961 ggcgttattg taccgattga agatttgatc gaagattata tgccaaatct gaagaaaatt
     7021 tttgatgaaa accccgaata ccgacaaatg tctactgcac ctgatggtca catttactct
     7081 atgccttgga ttgaagaatt aggcgaagga aaagagtcga ttcatacagt aaatgggatg
     7141 gcttggatca acaaggagtg gttggataat ttgggtcttg aaatgccgca aaccactgat
     7201 cagttgatga ctgtgttgga ggctttcaag acgcaagatc caaatggtaa tggtgaagca
     7261 gatgaaattc cttttagctt tattaacaat ggaggaaacg aagacttaaa atttttaatg
     7321 ggggcattcg gtctaggtga taatgatgac cacttagtcg ttgataacga tggtcaggta
     7381 caatttactg ctaacaaaga agggtataaa gaagccatca aatatttcaa tgaaatgaat
     7441 aataaaggtc ttattgataa agaggctttc gaacaagatt ggaatacgta tgttgccaaa
     7501 gggaaagaac ataagtatgg cgtgtacttt acttgggata aagcaaatat cacgggtgca
     7561 gatgatagtt atgacgtctt gccagtctta gcgggaccag atggaacgaa acatgttact
     7621 cgtacgaatg gcatgggttt ctcaagagat cgtttcgtaa ttactagtgc gaataaaaac
     7681 ttggaactta cagctaggtg gatagataaa atgtatgaac cgttacagtc tgtccaaaat
     7741 aactggggaa cctacggtga tgaagcacag gcgaatattt ttgaattaaa ggatggtatg
     7801 ttaaaacatt tgcctttaga ggggacagca ccgggggaac taagacaaaa aaccgaagct
     7861 ggaggaccat tagcagttct tgattcttat tacggcacag tcactactat gccagatgat
     7921 gcgaagtggc gtttagattt gatgcatgac acgtatttgc catatattac agaagacaat
     7981 atctatccac gtgtcttttt agaaaaagaa gaaacagatc gattagcaaa aatcgaaacg
     8041 gatatgtggg attacatcta tcgcaaaaga gcagagtgga tcaccggcgg taaaatcgat
     8101 gaagaatggg aagaatacct tgctgaattg gaacgtgtag gtttggaaga atggattcaa
     8161 ataaaacaaa ctggctatga taattttttg aagggagcac aataagtgtt agtagaagaa
     8221 acggcgattt tggataaagc aaatcgattt attgaaatga tgcgaggaaa agttaaccct
     8281 cagtatcgac aaaactatca tttttccgca cccatcgggt ggataaatga ccccaatggg
     8341 tttatatatt acaaagggca ttaccatctc ttctatcaat actatcctta cgatagtcga
     8401 tgggggccca tgcattgggg gcatgcgcgc agtagtgatt tggtccattg ggaagatcta
     8461 ccagtagcgt tagccccaga tcaaccttat gacagcggcg ggtgtttctc aggaagtgca
     8521 attgaaagag acggaaaact atatttattt tatacaggct gtcaagaaat tgatggtatt
     8581 agccatcagc atcaatgttt ggcggtctct gaagatggta ttcattttag caaatacagt
     8641 ggtaatcctg tggtagcaga aaaacagcta ggtgaaaatg ggctaataca agaatttcgt
     8701 gatcctaaag taattgttca caacgatggt tactatatgg tagtagctac taaatctaca
     8761 cagtctactg gtagaatagt gatgtttcaa tcgtcagatt tgtatacttg gcacttttac
     8821 tctgtgctgc tagaagggac ttcagagcaa ggaataatgt gggaatgtcc tgatttattc
     8881 catttagacg gacgagatgt cttaatcatg tctccgatac aaatcaagaa gaacggactg
     8941 gaatatcata atatcagttc taccatggct tgtattggtg aggtaaactg ggaaacaggt
     9001 cagatgatag ttgataattt ccatgaaatg gattttggaa tggattttta tgcaccacaa
     9061 acaacaagag atcctaatgg tggacgggtg atgattgctt ggatgcagat gtgggatcgt
     9121 acattgccta cacatgagtt aggccatctt tgggcaggct ctatgagttt gccccgagag
     9181 ttaagagtga aaaaaaatcg attggtacaa aaacccatct caactgtata tagtcattta
     9241 gtttatcaac aaggcagtga aaatattgca gtgactgaca catcagtcgt atttcgaaac
     9301 gcgctgtctg attcttcata tttacatcta gtcgcagatt tggagaaagc tgaagttttt
     9361 acaattgaat tactgcggtc taagacggat tgtctcaaac tagcctatga cactgctaca
     9421 caggtttttg aattggatcg tcagaaacta ggaagagagc ttacaggggc ggaagaagac
     9481 cctctgaatg tacgaaaagt tgaagtacct ttgattgata atcagctcgt tcttgagatt
     9541 tttagagata cctcatcaat tgaagtcttt attaatgggt tagaagttat gacggctact
     9601 ttctatgagc tggaaaaagc tcgagatatc ttgtttcatt cgatcggaga aagtcgtatt
     9661 caagcttttg aaacagcgag tgtgaaataa atgtttgatt gcttaggcga tgaatcaatt
     9721 atttaatagg ttttgaagga taatgttttt agaaaagaac agatagctag atttcccatg
     9781 gatttgctat tagtattttg aaaaaattag taatttatga caaaattcat tatactaaac
     9841 ttgtgcagaa atgtgaggga tcaactatga aagcaacaat gaaagatgtc gcaaaattag
     9901 caggtgttgg agtaggaact gtttcccggg tattgaataa cggttctgtt aaagcttcta
     9961 ctagagaaaa agttgaagca gcaatgacag agttaaacta tcaaccagat ttttatgccc
    10021 gggggttaaa gatgaagcat acgaacacgg ttgctttgat tctacccacg gtatggcatc
    10081 cattttttgg cgaatttgcc taccatgtag aaacagcatt agaaagacaa aactacaagc
    10141 tttatttgtg taactccagt ggtaatagtg aaaaagaaca agaatatatc cagatggtca
    10201 gccaaaataa agtagacggc atcattggaa ttacttattc agatatcgat gaatacattt
    10261 cgagtaatct gccttttgtt agtattgacc gttatttcac tgaagaggtg atttatgtga
    10321 ccgctgacaa tgcggccggt ggacgtttgg ctgcaaatga actttatcgc cgaggatgtc
    10381 agaatgtagc atatatcggt gggtaccaag aaacaccgaa tgaaacgaag agtcgtcgaa
    10441 aatattttga aatcgagtgc cgtcaactgg ggatttccta taaagcgtta gatatgttag
    10501 aacctttaga ccatctctca gaacgtgtaa caaatttttt gttagagaat cccgatatcg
    10561 atgggatttt tacgatcaac gatccaatgg cattagctgt cattgatatg cttgaaaaaa
    10621 tagggaaaaa cgtaccagag gatgtccaag ttatcggatt tgatggtcaa aagatgacag
    10681 aaggagatcc ttatctagtc tcaacgattg cccaacctac aaagcaaatg gcggaagtgg
    10741 cagtggcaaa attaattgct gtcattaatg gagagacagt agaaaaacgt accgtattgc
    10801 cgattgaatt tggcgaaggt gacacaacga aacctttagt gagaaacgat tttgcttagt
    10861 gcaaatacgt ttcttttttt gaaaatgagt gaatgaaagg tgtagataaa atgttatatg
    10921 gtggaataga agccggtgga acaaagtttg tctgtgggat tggtaatgaa caattacaag
    10981 tgatagaacg gaaaagtttt cctaccacaa caccagaaga aacgatggag caagtgtttg
    11041 atttctttga taagtacaaa ggaaatatcg catcaattgg tgtaggagca tttgggccta
    11101 ttgatattca aatcgaatca agaacttacg gatatatcac caacacaccg aagttagctt
    11161 ggcaaaatta tcattttgta ggagctttgg aaaacgcctt gtcggttccc atctattgga
    11221 ctaccgatgt aaatgctgct tgttatggag aatatatggc agggtatgga aaaggtaaaa
    11281 atagtgttct gtattacacc gttggtacag gtgttggtgg tggtgctgta gtggatggga
    11341 aaatagtcgc aggttttagt catcctgaaa tgggacatat gctcttacaa cgtcataatg
    11401 aagatcaatt tgaaggaatc tgtccttttc atcatgattg tttggaaggg ttagcatcag
    11461 gacctgcgat tgaaaaacgc tttggaagaa aagcccagac tatctcattt gatcatcctt
    11521 attggacgat tgaggcagat tatcttgctc agtgtgtgta taacacaacg ttactatatg
    11581 caccggaagt aataatttta ggcgggggtg taatgaaaca gccgcaacta ctcgagttga
    11641 ttcgccaatc gtttaaagaa aaaatgggtt cctacgtgga tacgcctact ctcgaagaat
    11701 atctactaac tccaaggctt gctgacaatg cgggcttgat tggctgccta gctttagcaa
    11761 taaagaaact caatcattag aatagtattt attagaacta ttcataacat accggaagtt
    11821 taaaagggta ttctgaaact taaatagtct caattcattc ttctttcttg agaatctgag
    11881 tagagacttt tattctgttt caaattaata taattacgaa atgatattga gtacaagaaa
    11941 gttcttttta ccagatcttt taaatcgaaa aatctgatat atatatttat agtactaaaa
    12001 atctgattag ataaaaagct aattcaatag gaaaataaag gtagtgaata aaagcaaagc
    12061 ccttgttagt agttaatcta acaagggctt tggtagggaa aatggtagga aaccatctta
    12121 ttttttacga aaatcaggaa ctttagtaat tgaataatgt tgatttatag gtattcctca
    12181 tccatattat gttggctctt tattcccact ccactgttgc aggtggtttg ctggtaatat
    12241 catacacgat acggttaacg tgtgcgactt catttacgat acggacactg attttttgca
    12301 agacttccca agggatacgg gcaaagtcag cggtcatgcc gtcaatagaa gtgacagcac
    12361 ggatacctac agtgtagtca tacgtacggc catctcccat aaccccaaca gagcgaatgc
    12421 ctggtaggac ggtgaagtat tgccagatgt cgcgatctaa accggcattg gcgatttctt
    12481 cgcgcaagat agcgtctgat tcacggacga tttctaattt ttcttctgtc aattcaccaa
    12541 ggacacgaat acctaagcct ggtccaggga atggttggcg ccaaacgatg ctgtcaggca
    12601 tgcctaattg ggtacctaat tcacgtactt cgtctttgaa caatgtgttc aatggctcga
    12661 tcagcttgaa ttgcatgtct tcaggtaatc cacctacatt gtgatgtgat ttgatggttt
    12721 gggcagtttc agttcctgat tcgatcacat cggtataaag ggttccttgt gcaaggaaag
    12781 aaacgccttc ttcaccggca agtttggttg cttcatcatc gaagacatat acaaattcat
    12841 ttccaatgat tttacgtttt tcttctggat cagacacgcc agcaagtttt gataagaaac
    12901 gttctttggc atcgactttt ataatgttca agccaaattt tccgccaaga ctttccataa
    12961 cttgttctgc ttcaccttta cgcaacaata cgtgatcaac gaagatacat gttaattgat
    13021 cgccgatcgc tttttgtaaa agaacaccaa caacagagga atctactccg cctgaaaggc
    13081 ctaataaaac ttttttgtca ccgacttgtt cacgaatttt tgcgatctcc atgtcgatga
    13141 agttatccat tgtccagtca ccagtacatt ggcagacatc tagtgtaaaa tggcgcaaca
    13201 agtcatttcc atattcggaa tggcgaactt ctgcatggaa ttggattccg tacattttgc
    13261 gttctgcatt ttggatcgat gcgatggggc aatctttgct ggtagcaacg acatcgaaat
    13321 cagtcggtgc ttgggtaact aggtcaccat gactcatcca aacggtttgt ttttcaggag
    13381 tgttttggaa aagggccgct tctgcagaag tgatttccaa ttctgctttt ccgtattcac
    13441 ggtttttggc tggtttaact tttccgccta atttataagt aatcaactgc ataccgtaac
    13501 agattcctaa aactgggatc cccaaatcaa aaatcttttc atcaatacca aaggccttct
    13561 catcataaac actgtttggt ccgccagaaa ggatgattcc tttagggttc attgccttta
    13621 cttcttctgc ggtaatgcgg tggctcatca actctgagaa aacaccgaac tcacgaatac
    13681 ggcgagtgat cagttggtta tactgactac cgtaatcaag tacgataatt tttggctctt
    13741 cgtcaaatcg tgttggtgaa gacaaatttg aataaaactt agtccgatat gcggcgcgtt
    13801 ctgtgcgccg catatttttt tagttttcaa agatcagacc ttgttgtaaa tagatccgtg
    13861 cccgaaagtt ataaaagttg cgataaccaa acgcaattcg tttaatcagc ttgatcttgt
    13921 tattcagccc ctcagtgacg ccgtttgagt gggacacctt aaaggcattt gaaatacccg
    13981 attggtagcg atggaagatc gtgaatttct ttttaaacga ctgaggtaac gtagatgaaa
    14041 ttgttttaag ggtttcttga aagccttccg ta
//
LOCUS       DAMEEU010000072        14039 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.073, whole genome shotgun sequence.
ACCESSION   DAMEEU010000072 DAMEEU010000000
VERSION     DAMEEU010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14039)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14039)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14039
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.073"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..125
                     /locus_tag="PB779_002228"
     CDS             <1..125
                     /locus_tag="PB779_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDE0739738.1"
                     /translation="NQGFISSVASKRNHIPRKSLNYQTPLEVFLSYVNGKFCLA"
     gene            complement(303..2300)
                     /gene="tkt"
                     /locus_tag="PB779_002229"
     CDS             complement(303..2300)
                     /gene="tkt"
                     /locus_tag="PB779_002229"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HDE0739739.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2402..2653)
                     /locus_tag="PB779_002230"
     CDS             complement(2402..2653)
                     /locus_tag="PB779_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HDE0739740.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2800..3423
                     /gene="lexA"
                     /locus_tag="PB779_002231"
     CDS             2800..3423
                     /gene="lexA"
                     /locus_tag="PB779_002231"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HDE0739741.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3603..3821
                     /locus_tag="PB779_002232"
     CDS             3603..3821
                     /locus_tag="PB779_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739742.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(4110..4622)
                     /locus_tag="PB779_002233"
     CDS             complement(4110..4622)
                     /locus_tag="PB779_002233"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HDE0739743.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4636..6933)
                     /gene="recJ"
                     /locus_tag="PB779_002234"
     CDS             complement(4636..6933)
                     /gene="recJ"
                     /locus_tag="PB779_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HDE0739744.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(7075..7518)
                     /locus_tag="PB779_002235"
     CDS             complement(7075..7518)
                     /locus_tag="PB779_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HDE0739745.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7519..8307)
                     /locus_tag="PB779_002236"
     CDS             complement(7519..8307)
                     /locus_tag="PB779_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0739746.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8304..9245)
                     /locus_tag="PB779_002237"
     CDS             complement(8304..9245)
                     /locus_tag="PB779_002237"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HDE0739747.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9422..10009)
                     /locus_tag="PB779_002238"
     CDS             complement(9422..10009)
                     /locus_tag="PB779_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HDE0739748.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10230..11537)
                     /gene="obgE"
                     /locus_tag="PB779_002239"
     CDS             complement(10230..11537)
                     /gene="obgE"
                     /locus_tag="PB779_002239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HDE0739749.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11831..12841
                     /gene="gap"
                     /locus_tag="PB779_002240"
     CDS             11831..12841
                     /gene="gap"
                     /locus_tag="PB779_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HDE0739750.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12926..13861)
                     /locus_tag="PB779_002241"
     CDS             complement(12926..13861)
                     /locus_tag="PB779_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0739751.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
BASE COUNT         3897 a         3134 c         2470 g         4538 t
ORIGIN      
        1 tcaatcaagg attcatctca tccgttgcgt ccaaaagaaa ccatatccct agaaaatcac
       61 taaattacca aacaccatta gaagtttttt tgagttacgt aaatggaaag ttttgtctcg
      121 cttaatttga caaataatat tctcaagaaa cacaaactaa tccgaagaat tctttgtttt
      181 gtcatttaaa tgtaacatag ccgaaaacga aaagtaatat tgatttattc ttctaacaca
      241 taaagaacag ctgtctccaa cttgcagaca gctgttctta tcagtcaaac aattgcttgg
      301 atctatgata gttgattgta cgtattcacg acattttcta ctgtaaatcc aaattcttct
      361 aaaattttag tgccaggggc agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct
      421 gttcctacgt agcgttccca tccaaatgat gcagcagctt cgatagccac acgtttcttc
      481 actgatttag gaagtacact ttctttatat tcagaagatt gtttttcaaa gaggtcaaag
      541 cttggcatag aaacaacaga aacatctttg cctttttcag ccaattcttt ttgagctttc
      601 acagccaaat caacttcaga acctgttgca atcaaaatac cttctggtgt ttctccttgt
      661 gatggagaaa gaacatacgc gccttttttc accatttcat ctgctacttc ttttgtagaa
      721 ggcaatactg gaaggttttg acgactcaat acaaggatag taggcgcatc tgttgtctcc
      781 atcgctactt tccaagcagc acgtgtttca tttccgtctg ccggacgaat cacttgaaca
      841 ccaggcatgc agcgaacaga tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct
      901 ccgacagcaa ccgagtcatg tgttaagacg taaacaacag gagtatgttg gattgctgct
      961 aaacgaactg ctggtcttag ataatcgaca aagacaaaga atgttccacc gtagatacga
     1021 gttccgccat gaagttggat accattcata gccgaagcca ttgcaaattc gcggacaccg
     1081 aaccagatgt tgcgtccttc ataatgttca ggagtgaaat ctttatctgc agccaccatt
     1141 gtattattgg aacctgacaa gtccgctgaa ccaccccaga agcttggtat agctttcgat
     1201 aattcttgga tgacttcttt acttgaaaca cggcttgctt gactgcttcc aacttcataa
     1261 gttggcaatt ctgcatccca gttttctggt agtttgccat caaaagcatc ttcaaattgt
     1321 tgtgctaatt caggataagc ttttttataa ttggcaaaca tttcattcca tgcatcttca
     1381 gctttttgtc cttcttctat catcgtttga tggaagcggg cagctacttc ttctggaaca
     1441 gtgaaatctg gatactccca accataaact tctttagcca tcttgatgcc atcttcacca
     1501 agaggagcac catgaacagc agatgttcct tctttaggag caccatagcc gatgactgtt
     1561 tttacttcga tcaatgttgg tttgtctgtt tcagcttttg cttcttcaat cgctttagag
     1621 attgcttcta ggtcatttcc gtctttcact aagatatgtt gccagccata tgcttcatag
     1681 cgagcaccaa cgttttctgt gaaagctttt gaagttggac cgtctagtga aatatcgttt
     1741 gaatcgtata aaacgatcaa tttccctagt ttcatatgac ctgccatcga acttgcttct
     1801 tgagataccc cttccatcaa gtctccgtca ccgcatattg catacgtata gtgatccatc
     1861 acattaaagt tttctttgtt atacgttgct gcaaggtgcg cttctgccat tgccataccg
     1921 acagccattg caatcccttg tcctaatggc cctgtagtgg cttctacacc atctgtatga
     1981 tgtacttcag gatgtcctgg tgttttagaa tcccattgac ggaattgttt caaatcatcg
     2041 attgtcactt gatagccagc taaatgaagc aagctataca acattgctga cccatgtcct
     2101 gccgaaagaa cgaaacggtc gcggtcagcc cagttttttg atgtcgttgg atttactttc
     2161 aggtgttttg tccataacgc atatgccata ggtgctgcgc ccatcggcaa tccaggatgt
     2221 cctgagtttg ctttttggac tgcttcaata cttaatgtac gaattgtgtt aacgccaagt
     2281 tggtcaattt tgtcaaacaa aataacccct cctattaatt taggtttttt ttacctttat
     2341 ttcttacact ttcattctat aagatgtcac acgaaaaagc aatctttttc agtatttttt
     2401 actaaaagtt gtcatttcgg ttgtgtaagc cttttttctt ttggatttct tttaattttt
     2461 ccggggtcac gtcattgccc tcaggatcga cgactttcat tccttcgata tgatgacgca
     2521 taccggaacg aaaagcttcc aaatactctt tgcgcaagtt gatttgttct tgttcttcgg
     2581 cttttgagag accattttcc ttctttttac gtgcaagttc attgatccgc tctatttttt
     2641 caggtgacag catgctcagc cctcctttta ctctccttca tattatataa aaactgaaaa
     2701 aaaaacaact agataaacta aataaaatac gaacattcgt ttgatttagc gctttttata
     2761 tggtactatt tatttatcaa gtgaaagaag gtgtaccttg tggcccgaca aactgaatca
     2821 agacaaatcg aagtcttacg atatatccat gaacaagtaa cccaaaaagg atacccgccg
     2881 actgtccgtg aaatcgggga agctgttcag ctttcttcta cttctactgt tcacggtcat
     2941 cttgcacggc ttgaaaaaaa agggtttatc caaagagatc cgacgaaacc tcgtgcaatc
     3001 gagttgacaa aacaaggttt agaaaagatt gggattcgtc caacaactat tccagtactt
     3061 ggcgtcgtaa cagctggaga acccatttta gcagtagagg atgcttcaga cttctttcca
     3121 atccctccta atctttcttc cgaagaaggc agtctcttta tgctgacaat tcgtggagat
     3181 agtatgatca atgctgggat attggatggt gacaacgtga tcgttcggaa gcaagaaact
     3241 gctcaaaatg gcgatattgt cattgcaatg actgccgagg acgaagcgac ttgcaaacga
     3301 ttctataaag aaaaaaactt tttccgtctg cagcctgaaa acgacttgct cgaaccaatc
     3361 atcttagatc aagtatctat attaggacga gtagtaggac tttatcgtag tcatatctat
     3421 taattgctac taattaaaag aaaacttttt aaaaagagtt tgagacgttg gtctcaaact
     3481 cttttttcgc ccgggttctt cttctttcaa atttttatca cttccctctt tacaaaccga
     3541 acaaatattc gtatactaaa tatacgaaca attgttcgca taaattaaag aggtgagaat
     3601 tcatgaaatc aatgagacgt cttggcttag tattaactgt tttgttttta ggtattatta
     3661 ttggtaattt cggcatacgt ccagctttac ttgtgtttgt tccgttattt actttgtggt
     3721 tcatgttgtg ggatgaaaag aagtaccgtc aatctgagcg gcgcagaatt catgaagatc
     3781 atttctatca tgagccctac tacagatcca ggcaatcata ataaggattg actgctaatt
     3841 attcaaaaga caagaagtta aacttttacg ggggtgtgac aaaaatcggt cacatccttt
     3901 ttttcgaata aacggtgttc taaagccagt ttttcggtat taagtcaaat tgcggaaaaa
     3961 gtgatttttt aaacttctac tggtctttgc ttgtttccat ttataaaaaa atagcgaccc
     4021 tcaaaagtca gatagagaat ctgacttttg agggtcgctt taaaatcgct tctttaagaa
     4081 tatcatcaag aatagcttct tttttctgct taatattcca ttaatgtaat gatgtcatat
     4141 cctttgattt tgtcgcgtcc atggagatcc atcaattcga tcaaaaatgc gcagcctacg
     4201 actacaccgc ctaattgttc gatcagttcg atcgtcgctt tgattgttcc tccagtagct
     4261 agcaaatcgt cacaaatcag cacacgttga cctggtttaa tggcatcctt atgcaatgtc
     4321 aatgtatctg ttccatattc taatccataa gtcacttcga tggtttctcg aggtaacttc
     4381 ccttttttgc ggactggggc aaaaccgact cctaactcat aagcaacagg acatcctacg
     4441 atgaatccac gggcttctgg cccaactacc atatcaattc gtttttcttt tgcataattt
     4501 acgatttgtt tagtagcttc ccgataagcg tcaccatctg ccatcagtgg ggaaatatct
     4561 cgaaacacaa ttccttttga cggatagtcg ggaatactgg caatataatc ttttaaatcc
     4621 actctttgtt tcctcctagg ttgttaacca tttctttatg gtaggaatat cgctcaaaag
     4681 caaaaattcc tcaactttga ttttattgag ccgtcgctgg tataatctgc tctcagtcaa
     4741 aggatgactt tctgggctag cgactttttg taaaacaccg ttctctattg taacaaattt
     4801 caattcaaaa aacacctgta tcataaaaat taataatttt tcagggatac gcaaatattg
     4861 agctattgct tttattttat gacgtatatc aattcgttct tgagaatgga tcaatttaaa
     4921 caattttgcg tactgttctc ttgtgcctac cccattcaaa taggcctcat caggtgaaat
     4981 ccccatcaga taaacacgat tgaatgaata agaccgaaaa acttctttca gatccgctaa
     5041 atcatctgga caatccataa caactagaga gtttggtttt cttttttcaa ttattgcctt
     5101 tacagaatct agtccttcga aaacaatcgc agcttcctgg ataatctcag gcacgaattt
     5161 caacgtcgaa gaatcaaatg ctaaataaag gctaccttcc gacgttcggc tctgttcacg
     5221 gaaacgtttt gcccgccaat caaatacttg cagaccaccc acagaaaaat cagataccat
     5281 cagctgcggt ttcttacgcc cgttccattc attgatcgaa agctttccta ccacatctac
     5341 ctgattattc agcagttctt cttcttgagt accaaaacca aaagcgaccg catcaagctg
     5401 actcgatgca tcggaaagga caaatttcag atgctgttgg tttgctccga ttcttttgat
     5461 attttctgct tggacttgtc gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg
     5521 cgccaatagt ttcagctcat caattcgctc tactgttact tcatttggca gcaatacttc
     5581 atcaattctc aactcaggcc ctctcatcaa gtcaatttga tgatcgacta tatattggtt
     5641 catcttctcc tgtagtatag tgacattttc acttggcatc gttaaaccga ctgctgcatg
     5701 atgtcctccg aagtaagtaa ataaatctcg catctggtca agcatttcaa aaagattcaa
     5761 ggcttcaata ctacgtccag atcctttagc tgatccatct tcttttaaag taaggacaag
     5821 cgttggttta cccgtttcat tcattatttt cccagcaaca atgcccaaaa cgccttcatg
     5881 ccatcctcgg tttaccaata gatggatatg attctcctta ttgaccatcg ctaatgcttc
     5941 ttgtgttatc tgctctacga ttgcttttct ttcttcattg atctcattca atttttttgc
     6001 ttgaacggat gcttcctctt catcaaacgt cgcaagtaac gagacggcag gacgtggatc
     6061 gcccatccga ccgattgcat ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc
     6121 tgcgtccctc atttttacgc cgctttcttc aaatagcgcc tgaagtccta tccgttctga
     6181 atgatgaatg gcatcgattc ctaatgaaac aaggattcga ttctcatcag tcaatgaaac
     6241 taaatcggcg atcgttccta tcgctactaa atccaaaaat tctgcaggcg gttcttccaa
     6301 taatgcagaa gctactttga atgctactcc gactcctgcc aaatctggaa atggatagtg
     6361 ccccgctgga tgacgagggt gaacaatcgc ataagcgtct ggtaaattct caggtagttc
     6421 gtgatgatct gtaatgatca cgtctacacc agcttgctga gcgtatgcta ccgcatcatt
     6481 tcctgctacc ccgttatcaa cagtgatgat caactggatt ccttcttcga tcttttcttg
     6541 gtataccgat tggtttggtc catacccatg ctcaaatcga tttggcagga atacttctac
     6601 ttctgcacca agtaattcca gtgtttcttt cattaccgtt gcactggtga tcccatctgc
     6661 gtcataatca ccgtaaacga ggattttttc tccactgatt acagcttctt ggattcggct
     6721 gattgcttta tccatatcgt gtatcagata cggatcatgt aattcttgtt cctttggatg
     6781 taaaaatcgg ttgatatcct tttcctcatg gtaacctctt tgccacagta acttaccgac
     6841 aaatggagat aatttcagtt cacggatcat ttggagaaag gattcagaag gctctgtctc
     6901 gcttaacttc caatcaaaat ttgcttgtct cactttctca ctcctaactt agttattata
     6961 gcaaaggaaa tcagcaaaaa aaagcagaaa gaaagaataa aaacagatca gatccgctag
     7021 acagatgttc agcaggacct gatcttttgt acgaccattt atgaaatatc cctattagtc
     7081 aaaataattg aagctttgtt tgggcgattg agttttttgt tcttccggcg ctttcaattg
     7141 actgatttgt gcggttttcg cttgtaactc cgcctgataa gcagcttcca actccgcacg
     7201 ttcgtttcta aactcgcgtt gctgttcttc ttttgcttct tcaattttct tttgaagttc
     7261 tgtttgatat tctgacattt cctgagtcag ctgtttgatt tgcttttttt gctgccatag
     7321 tgttgccgaa gcagtcaaaa atacaatcag tgcaccaatc agcgcagaac cgatgatcac
     7381 taagatcaat ggcgcagaaa aggaagtgaa gccaaaactt acaggaacat ttttattgtt
     7441 caatacagca aaaagaacaa taatcaaaac taaaacaaat ccaagaatca cattgctttg
     7501 ctttttcaat tccttcacct actttttgtt aaaaattccg ctggctaaat aatcaccaat
     7561 cgttggaaac agcgtataaa attttgatgc aacttctaaa ataaacggtt gattgatttc
     7621 ccgttttgga tgtctcatat tgcggacgat catttttgcc aacttggcag gttctaaaac
     7681 gatttgtccg actttttcca aatagcttcc gcttggatca gccttatcga agaaatttgt
     7741 ctcgattgga cctggattca ctgtcgtaac agctacgcca agtggtttca attctaatcg
     7801 caaagcgttg gagaagccaa ggactgcaaa tttcgtggca gaataaaccg ttgattttgc
     7861 agttgccatt tttccagcca tagaggcgat attaatgata tgaccttgtc ttctttctgc
     7921 catatcgatc gcaaattttt gtgtcaaaac catcattcct aagatgttga cttcaaacat
     7981 atcgtatgct tttccaaggt cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt
     8041 gtttaccaga atatcgacgc gcccgacttc ttccatcacc ttttcatata attcgtccac
     8101 gctttcagga ttgctgacgt ctaccttgaa agcataagcc tctttgccgc tcaagcgtct
     8161 gcactcgtct ctgacacctt ctacaaatgc cattcttcgt gcgcaactta taacgattgc
     8221 tccttgcttt gctgcttcat aacagatttg tgcgcccaga ccgcctgaac tacctgttac
     8281 taaaacaact ttatcttcta aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg
     8341 ctatcaaaat ctttcataat cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc
     8401 tctaaagctg cttttcctaa atatctcgca ctgatatgag taagtagcag ccgttttgcc
     8461 tgcgcttctt ttgcaacttc agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc
     8521 attcttgctt catctttatt aaatgtgctt tcatgtacca gaatatcgct attttccgca
     8581 agcacaacgg aattatgtgt ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt
     8641 ttatctggac ctacgaaatc ttttccattg atcgtccgcc catcttctag ttggatcgtt
     8701 tcaccttgct tcagtttgcc gtacagtggt ccagctggaa tacctaattc ttttagacga
     8761 tccacctgca attctccttt atgatcatgt tcaaccacac gataaccaaa actgtcgatc
     8821 ccatgattta gtttttttgt ataaacagaa aattgctgat cagtaaaaat cggggctgtt
     8881 tcatttagct caatgaattt cagcggataa cttaaacgcg tttgcgaaat acctaaagag
     8941 acttttatgt attcctctat cccttttggc ccgtaaatct ctaatggcgt atccccacct
     9001 tgaaatgacc ggctgctgat gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt
     9061 gtaatgaaaa ttttaccgat ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc
     9121 gtgccttcgc cacagtcgaa caaccaaact tcattgcgct cgtctaaaag tttcaatgct
     9181 atacttgtca catttctatg ttttgcagga acacctgcac ctgttcctaa aaattgtaat
     9241 tccataatct acctgacttt ctttaagttc ctctttaatt ttagggtaaa aagaagggat
     9301 aatcaaccgt aagtcgagaa tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt
     9361 ttctttgaaa attactataa aaacagcagc gaacccgttt gagatcctct gctgtttttt
     9421 attaatttga agatccagaa ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc
     9481 aagtcttttg tgcagcttct ttcgcatgat tttcagcttc tttcgcatca tgcacatctt
     9541 tttcgacatc ttcataatcc aagcgagtaa tttctccgcc taattccatc attaccaatt
     9601 gattcagtgg gcgattgtcc tcttcatcag caatcaagat cagtcctgta gctccttcac
     9661 cgattttatt tcctacaaag tcgaacacgg tctgggcatc ttttatttct ttggcatctt
     9721 gtgtcgcacc gatcattcct ccggcaaacc atcctaataa aatccctagc ggaccaccta
     9781 atacaccaac caacattccg attaatccac ccgtagaaga tttgttatta ccggtaaagt
     9841 cgataaaatc ttctattttg aattgatgtg tcccattagg atcatggctg acaactgcca
     9901 tctgttctcc tttaatcgaa cgaacagcat gtaacttttt gatttctgaa aatgcctgat
     9961 atgcctggct ttctacttga aaatttaaaa tgattactcg tttgctcatt aaaaacgccc
    10021 ctttcatacc ttcttgttat ttattttacc tttaattgta aaataagaaa agaaaagcac
    10081 tctttttttc caataaaata gggctgtgac aaaagtcgta tcacagctcc tttttccgaa
    10141 taaacggcgt tcttgaagct gatcacttct gtcacaacct cccttaaatc tgaatctata
    10201 ttttttggta tttgttttta tttgcttgcc tattcgacaa attcaaattc aaactcaccg
    10261 atacgtacaa ggtcgccatc tttcgcaccg cgtgcccgaa gagcttcatc cacacccata
    10321 ccacgtaatt gacgagcaaa acgcatcact gtttcatcat gatcgaaatt cgtcatttgg
    10381 aataattttt cgatcttctc accagataag atccacgttg catctgaatc acgatcgatt
    10441 tggaactcag gaccttctgg attgaatcca tagtgtacag tttcttcttc cagttcttct
    10501 tcgtacaatg ggaattctgg cgttacttct aacaaatctg ctgtagcatt caataacgcg
    10561 tccaatcctt gtcgagtcac tccagaaatt ggaaatactg ggatgtcatc agcaaattca
    10621 tcttcttttt ccttgttcag ctgttctttg aatttcacta gattttccgg tgcatccggc
    10681 atatccattt tgtttgccac gatgatttgc ggacgctcta gcaagcgtaa gttataagta
    10741 gataattctt tgttgatggc aagatagtct tcataaggat ctcgtccttc catcccactc
    10801 atatcgatca catgtaaaat tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc
    10861 agcccaacac cttgcgaagc tccttcaatc aagcctggca agtctgctgc ggcaaaactt
    10921 ctgccatcac ttgtagtaac cattcctaga ttaggtacga gcgtcgtgaa atgataagcg
    10981 ccgatttttg gacgagcaga tgaaataacg gatagtaaag tcgatttccc gacagatgga
    11041 aaacctacaa gtccaacgtc tgccaatact ttcaattcta gttcgatttt tcgctcttgt
    11101 cctggttcac cgttttcagc aatttccggt gcaggattcc gaggagaggc aaaacggata
    11161 ttccctcgtc caccgcgtcc accttttgcc acaactagtg tttgaccatt ttcaattaaa
    11221 tctcctaaaa gagcaccagt ctccgcatct cggacagtgg ttccttgtgg tactttaaca
    11281 taggtatctt ctgaaccacg accgtgcatc cctttactca tcccattttc acctggctgc
    11341 gctttgaaat ggcgattgaa ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc
    11401 aagatgacat cgccgccacg accaccgtct ccgccagccg gtccgccgtc aggaacgtat
    11461 ttttcgcgac gaaatgcaac cattccgtct ccgcccttgc cagctttcac atcgatcgtt
    11521 acttgatcta aaaacatgga cataattaag tcctcctatt attcatttat ttatttgact
    11581 gcctgaattt ccacaataaa caaaagtctt acttatttta tcggtgaaat ctgattttgt
    11641 ctatcatttc agcaaaaaga ttgtttacct tcttcttttt ttatcatttg gtaaggtttc
    11701 caaccttttt tctgctacca agtataattt tttgacaaaa tattctttgc gtagcagaat
    11761 aacagtgtat taattgtatt aattgaggat gccgtttcac agcaccccta ataaaggagg
    11821 aacttttgat atgacagtaa aagtaggtat taacggattt gggcgtattg gccgtctggc
    11881 tttccgccgc atcaaagaag tctcagatga tattgaagta gtagcaatca acgacttaac
    11941 aagtccaact atgttagcac aattattgca atttgactct actcatggta cttatcctgg
    12001 cacagttact gcaacagaag actcaatcgt agtggatggc gaagcaactc gtgtttatgc
    12061 agaacccgac gcaagcaaaa tcccttgggc aaaagaaaac ggtgtagata tcgtactaga
    12121 atgtactggt ttttatacat ctgaagaaaa agcaaaagcg catttagatg ctggtgtcaa
    12181 acgagtagtt atttctgccc cagctggtgc tatgaaaacc atcgtctata acgtcaatga
    12241 tgatacatta gatgaaaacg acaaaatcat ctcagcaggt tcatgtacaa caaactgttt
    12301 agcacctatg gcttatttct taaataatga atttgggatc gaagttggta caatgacaac
    12361 agttcatgcc tacacttcca cacaaatgct cttagatgga cctgtaaaag gcggtaattt
    12421 gcgtgctgct cgttcagctg ctgacaatac tatcccacat tctactggtg ctgcgaaagc
    12481 aatcggctta gttatccctg agctacaagg aaaattacaa ggacacgcac aacgtgttcc
    12541 agtcgttgat ggttcattaa ctgaattggt ttcagtattg aaaacaaaag taactgctga
    12601 tcaagtaaac gaagcaatca aaaaacacac agttgacaat ccttcattcg ggtatgatga
    12661 ccgtcaaatc gtttctagcg atgtcattgg aacaactcaa ggttcgatct ttgacccaac
    12721 gcaaacagaa gtaacaactg ctggtgattt ccaacttgtt aaaactgttg catggtatga
    12781 caatgagtat ggatttactt gccaaatgat tcgcttacta gaaaaattcg ctaacttgta
    12841 atttgataga tcaatcgata aaagaagcct ttgactggat ccagtcaaag gcttctttct
    12901 tttcatcccc tacttttaaa ctcgttcaat gaacatattg gcttaaaaat tgttggacta
    12961 cttgctgata tttttcagga tctgtcttgt atgcttccgc atgctcggct ccttttacaa
    13021 catacttttc ttttggtccc ttcgttgcac gatagacctt atctaacatt tcaaatggta
    13081 caaatgtatc ttcgtctcca tgtataaaga gcattgggcg ctggtttttc ttcaattgtt
    13141 ccactgcatt tgcttcaccg aaaaagtagc cagcacggac ttttgtcact agactcgtta
    13201 cttgcataag cggaaatgct ggaagactaa acatatcgtc tagctgataa gcaagctcat
    13261 catgaacgga agaataaccg caatcttcaa tgattgcttt cacattatct ggtagttttt
    13321 ctccgctagt catcataact gttgctgctc ccatgctgac accgtataga acgatttctt
    13381 gcgattttcc attgttttct agcactttgt ttatccactg tacatagtct ttacgctctg
    13441 gccatccaaa tccaatgtaa tccccttcgc tttttccatg tcctcttgca tcaggaacaa
    13501 ggacattgta acccatatca tgaaacatct ttgcgtaatt ggtcatcgtt tcagcgtttc
    13561 ccatatagcc atgagccaca agagctgttt tttcactttt cgtttcagca ggaagataaa
    13621 tcgctgataa tttcagaccg tcttttgaag tgatggtcca atcgcttcgg ttttcttttg
    13681 aactaaacca tttatgtgca tccgtttctt tggatgtctg tgttgtacca ggtgtatctt
    13741 cgtctaaaaa gtctttctca gaaggcacaa cagcataatt ataaaaataa ttccctgcaa
    13801 acactaacgc aacaatcaga gctaaagcga cgcctaaaag gattttcatc caaagtttca
    13861 taaatcatcc atctcatttc tcttttttca tataaccttg aattagtata atcaaagaat
    13921 ctctactatg caatgttcat ttttataacc cgcgaattgt aaaattaagt tagaaaaata
    13981 aaaaggcatt tatggtacac tcaaattgta tttccgacga aagaaaacaa aggagtgta
//
LOCUS       DAMEEU010000073        14017 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.074, whole genome shotgun sequence.
ACCESSION   DAMEEU010000073 DAMEEU010000000
VERSION     DAMEEU010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 14017)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14017)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14017
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.074"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..282)
                     /locus_tag="PB779_002242"
     CDS             complement(<1..282)
                     /locus_tag="PB779_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HDE0739752.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTEL"
     gene            complement(633..1325)
                     /locus_tag="PB779_002243"
     CDS             complement(633..1325)
                     /locus_tag="PB779_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDE0739753.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1762..2331)
                     /locus_tag="PB779_002244"
     CDS             complement(1762..2331)
                     /locus_tag="PB779_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDE0739754.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(2405..2728)
                     /locus_tag="PB779_002245"
     CDS             complement(2405..2728)
                     /locus_tag="PB779_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739755.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2882..3694)
                     /locus_tag="PB779_002246"
     CDS             complement(2882..3694)
                     /locus_tag="PB779_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739756.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            4048..4896
                     /locus_tag="PB779_002247"
     CDS             4048..4896
                     /locus_tag="PB779_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HDE0739757.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            5041..5982
                     /locus_tag="PB779_002248"
     CDS             5041..5982
                     /locus_tag="PB779_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HDE0739758.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKAFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5972..8143
                     /locus_tag="PB779_002249"
                     /pseudo
     CDS             5972..8143
                     /locus_tag="PB779_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
     gene            complement(8255..10426)
                     /gene="copB"
                     /locus_tag="PB779_002250"
     CDS             complement(8255..10426)
                     /gene="copB"
                     /locus_tag="PB779_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HDE0739759.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIR"
     gene            complement(10446..12632)
                     /locus_tag="PB779_002251"
     CDS             complement(10446..12632)
                     /locus_tag="PB779_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HDE0739760.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGLIAVADQIKLEVKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLCLNRHMKK"
     gene            complement(12632..12841)
                     /gene="copZ"
                     /locus_tag="PB779_002252"
     CDS             complement(12632..12841)
                     /gene="copZ"
                     /locus_tag="PB779_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HDE0739761.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            complement(12854..13294)
                     /locus_tag="PB779_002253"
     CDS             complement(12854..13294)
                     /locus_tag="PB779_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HDE0739762.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYYPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            complement(13368..13907)
                     /locus_tag="PB779_002254"
     CDS             complement(13368..13907)
                     /locus_tag="PB779_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDE0739763.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQLFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
BASE COUNT         3984 a         2900 c         2459 g         4674 t
ORIGIN      
        1 taactctgtc gaagtctgta ctttatcttg ataattaaat gcagacatac cactttgtat
       61 aattgtaatt attgctgaag caattgaaac aatcaatagt aaagacctgt gttcggaagc
      121 ctgatcaatt aatattggga tactagctga taagactatt tttataatat ttccgatacc
      181 aattactcta ttataaaatc gaatttcttt ttttaatcta tcgattgtag aatcaataga
      241 ttcgataaac gctttttgat ccatcatttt ctctccaatc attttattaa aatcattaac
      301 aaaaatatta taataggatt taagtaagtt ctaactaatc acatataaaa ataaaaaaac
      361 atttgtattt tatcaaagtt ttattatact tgtcaatttg tgtacatcct aaaatataag
      421 ctatttgttt acttctgtag aatatatact ttgttgttag ataagttgca catgtttata
      481 gaatctaaat aataaatttt tatgtaccgc ccctcaaagt gaactgaacc ccaaaagttg
      541 aactatttaa tggactatct ccagtagaat atcggaaaca gtccattaaa tagttcaact
      601 tttggggttc agttcaaaga gggggggatt ttttatcgtt gtggaatatt taaataccaa
      661 cgcttgtcat gaaaatcttg tgctccaccc ttagtatttc cttctggatc gtttgtcgca
      721 cgcatcatga cgtatacttt cttattaggg aaatcacgca tattgaaaga tacatgatag
      781 ccaacatttc ctaaagtatt ataagcttga tttacgtctg gtctataaat cccatcagct
      841 cttactctag ctagttcttt tccagtattg tagtccataa tgaaaatata ctcgtattta
      901 taattagcaa tgtgccatcc agctacatgc aagtttgcgt tttcgatttc tccgaactga
      961 tcaatgtggg cgtaatttgt tccatctgtc agcgtagaat ttgcagcacc tgctcgagtt
     1021 ggatcaatta ctggtttatc ctccgaagta gttggattat catccgtaaa accatgagcc
     1081 aaatcatagg ctagtttttc tttacttaca cccatttcag aaagataacc gtaaggatct
     1141 gtatgatcgc cccaaatatt ttgtgttacc cataaatgcg atttgattcc tggttggtta
     1201 taaggagtgt ctaatgttaa tggaatacca tatttcattg ctgaatctct tgccaattca
     1261 acgtatactt tatagttctt ttcaaaagtt tctttatcat gtgtatgttg taactcgatt
     1321 tgcacaggac ttttggctca cgaggttgtc ctactctaca tcttgctgat agatatgctg
     1381 aaaggaaaac accaacatta tgttttgctt tttcagctag aacgagacaa gcaggaatac
     1441 ctttagaaga tatcaaaggt tttttaggtc ataaagatgt ttccactaca caagtctatg
     1501 cccatatttc tcccgaagtg aaaaaaagat caatgaatca actagaaaac tatatagaag
     1561 agcaaataaa aaagcactca aattgagtgc ttttttaagc tcactatcac taaaactatc
     1621 actaatttta tttataagcg aacatgtttc tatcactgat tttttaaatc tagcgaaaaa
     1681 cccttatctt aaaggcgttc gttcaattct ttggcaaggt cttcaaagcc tggcttgcct
     1741 agaagtgcga acatggtttt cttatagctc atgtagaaaa attttcttga tgatgatttt
     1801 atccatcaat tgagattgac tgttttgctc tcctatgatt tcagctatga ttgtccgatt
     1861 ttgcggtttt cttcttaact ggtagttgat tttcccagtt tccatcaact cgctaagcat
     1921 atccacgact ccgccaaatc cggtcttttt cgtaataaaa cctagtgcta ccattcgttc
     1981 atctagattt tttgctgtaa tcgtcacacc agtaatgagc gagtgctgta atgtttgggc
     2041 cagctcttcc atcccttcag cattggatac gacggaagct gttttgttaa taggttcttc
     2101 gtttatttct tttggttctt tcctctccac tttcactgtt tgacgaagga catctagttc
     2161 ttgcaagagc gtttcgtatt gttcttgggt cagcatcacg ccagctactt tttcacgatt
     2221 aaatatatat acgccagttc ccgcgtctcg cgcttgagca aatacatcca tcggcgatcg
     2281 tttcacttct gtgatcgaag atgtgggaac ttctaatttc tttaattcca atggatttcc
     2341 tcctttacta atcgcttttt attatagcac agactgactt gttttgatct tttttccaaa
     2401 ggttttatcg gtttttgcct aaccagtaat tgatatcggt aagaagtctt tcgataccaa
     2461 atgaaggatg gtacagatac gttttttgat cttcgttatg gtctagtgga aaaaaatgat
     2521 cgatgatcac tagatctgca taccgaggcg gcttatttcg agtacataca tgtatagaga
     2581 tccgttttcg atgtcttagc gttttgttca gtaccccagc aagtcttctt gcttcttggt
     2641 gttcatagcg aaaaaaaaag acgattttca cttcaggagg gtggacatct aaataccctc
     2701 gttcctggag tgttttcagt aaaagcatcc cccactctac tgcggggtgt gcaagtgctt
     2761 gttggatcgc tagccgaaat tgatatagtt tatctttgga attgggaaat ttttctaatg
     2821 tttcctgata ataacgaact tcttctatca gccggtcatg gataccaatt acgtaacgaa
     2881 gtcattcttg gtaaagtact tttgtcagct ttgatttgct ttcgctctca aattcgctat
     2941 tcagccaaaa cagcgaatca agcttttcag tcacaatcgt caatttccga tagtcttgtg
     3001 tctcttctat ccgtttccac cgcttttcag taatctggtt acagctcaag cgcaaaattg
     3061 ctagataatt tttttctttt attggcaaaa tctgctcctc tctaaatagc aattcaggaa
     3121 acaattcaaa gaatagtgtt cgactgtctc ctaaaatctc gatttctgcc ggatcctttc
     3181 tttgcttcaa taattggatg aacatctcag aaaaggactg ctctccatca tctgcaaaaa
     3241 aatgcggaaa atctttcaaa aagcaaaaca gcagatatct tacttttctt tctgaaccaa
     3301 agatctgtgc ttttttataa gaaaaagaaa ggtggtactc gccaaaccac tttctcaatc
     3361 gctcttgcgt agaacgatcg tacttctgct cgtaaggttc attcaatagc agatttttca
     3421 gtaaacaaaa cgggggtgat tggatcagaa aaacaaacaa gagataaggt tcgctatatc
     3481 cttgatcata aactaactga acggttttct tatgaagaat cagctgaatg ggacagtcgc
     3541 tttccgccaa acgtttcaga tgccgatcca ctgttttaac atcgattttc agttcttcag
     3601 ctaaatcagc ttttcgccag atcaaatctt tcattagatt gattagtgaa aataaattct
     3661 gtgcattttt tgataatagt ttttgccatc tcatcgatca tttctcacct gatttctaaa
     3721 catattgttt gatcaaaatg ggttcactcc taaaaagata aaaaactccc tttctattta
     3781 tttaaatacg caaatcttcc tcattatttt ttattttact caatttaatc gtattctcat
     3841 ttcaaaacga atgtacttta aaaaaacata ataagatcac tttgcttgta ggatgtattc
     3901 ccttccatta caatgaaata aatagcgatt ttatgagaag gtgatgtgaa aatggaagaa
     3961 aaaatagaag aatccaaaca aaaaatcgat cagttgatat aagaattaga aaaagcggtc
     4021 atcggcaaac gttcaactat ccaattgatg atcgtggccc tattagcagg tggtcatgtc
     4081 ttattcgaag atattcccgg tgtaggtaaa acgttactgg tcaaagcact agcaaaagct
     4141 gtacagggaa ccttcagcag agtccaatgt actcctgatc tgctgcctag tgatattctt
     4201 ggtttttccg tatacaattc acaatcaaaa gagtttgaat ttcgtccggg accgatcttt
     4261 accacgatct tgttagcaga tgagatcaat cgtacgactc ctcgtactca gtcagcactt
     4321 ttagaagcaa tggccgagaa tcatgcaacg atcgacaaca atacataccc tctagacaat
     4381 catttttttg tcttagctac gcaaaatcca atcgagtacg aaggaacata tcctttgccg
     4441 gaagcacagc tcgatcgttt tttattccga ctacaaatcg gttatccttc ttttgatgac
     4501 gaacttttgc tacttttgga taaattcgaa aaagtgttgg ataacttaaa tgaagtattg
     4561 aacagttatg aaatagaaga aataaaaaca aatgtggcga atgtctttgt cagtcccgaa
     4621 gtggcatctt atgccttgca gttagtgtca gcaacaagaa gtcatgctgc catccagctt
     4681 ggcatcagtc cacgaggaag cctttccttt attcaggcag caaaagctta tgctttaatc
     4741 catgggagaa attacgtcac gcccaaagat ttgcaggatt tagttcctta cgtgttttcc
     4801 catcgcctga ttttttacga tcgttcattg aaggaagacg aaaagaaaca aatcattcat
     4861 actcttgttg cacaaattcc tattcctgtg aggtagattg aggtagacaa tggaaaaaat
     4921 caaagattat ttcattaatt ttgtgttatt tctggtatat ttcatcattg tgctttttgc
     4981 tcttgtattc aacaattctt taggctggtt cttgttggcc ttttttactc tttatgtatc
     5041 atggagcttg atttcattaa gcagctttct aaagaaactt tcggttactt gtacattgca
     5101 gccactcgtt tatcgcaaaa aaagtatgca ggttattttt tccatagcaa aaaagagaac
     5161 tttttcttta cctctccctc gtttacaaat cggcttccca gcaatctttg cagaaaaaaa
     5221 caagagattt tgattcttac aaataaaccg caagaagtcc aattgctttg gcagccaaaa
     5281 gaaagaggat gccatgaaac attaactgtc atttttacag cctatgatag tctaggactt
     5341 ttcagaaaaa gtgcaaaaag agagatctct tttcctgtga ctgttctgcc tgctttttgt
     5401 aagattcaag cagaaaaatt acagagagtt ctggaaaaaa aacagcagct gaacgcgtac
     5461 caaagaggtc ttgattttcg ggaacatcgc gcttatcgtc caggtgattc tttcaaccga
     5521 atcgattgga aattgtctgc tcatactcaa gagtggttat accgtgaata cgattatcaa
     5581 gaagaagaat gttctcctct tttttgcttt tggggttcgc ccagtccaaa atttgaacct
     5641 ctgctagact tgtatttttc tttatggcat ttgagaaaag aaaagcagcc ggaacttctg
     5701 atattaggca accgcgcctt tcatggcaaa gaccccggtc atacctattt tgcttctttg
     5761 gaagctggcg atgagaaagc ttttttcgca cacttgaaaa aatatgcaaa aaaacaaatc
     5821 gtcctctttg ttcctgagaa ttctcctgaa gtctcagaag ctattgaaac attgtcaaaa
     5881 gatcgaacgg tttatcttgt ttatttcgta gaaaaacaac tcatggtcca agaaaaagac
     5941 aagatatgtt cattgccagg aggtgaatgg attgacgatt aaacgggaaa aatggctgcg
     6001 tggcgtttac tcctttgtga tactaagtgt aggtgctccg atatttgtag tagctaatca
     6061 attgcaaaac agctaccttc ttatcctaac tattggtgtc ctatgcctta ttgtctgctg
     6121 tattcctaaa aaatgggtac gtttgctgct ttctttgcca gtaatgatag gttgtttgtt
     6181 tttatatttt ccttcgaaga cattttccat attatggatc ttacagtttt tttcgtcagt
     6241 cacagaggaa ttcttccatc tatcccaagg taaactttat tatttgccag aaaagacagc
     6301 tttttttctc ataatgttgc tgatctattt atttattaca ttgaccgtgg attacgacta
     6361 ttggtacgca ccctttcttt ctttgatggc ttacttcatg atgcttaccg tttttcggaa
     6421 aaaagattta ctgtacgaaa tgattgcggt agtaactgtt ttgttcgtgt atctggcagc
     6481 aaggcaattt ttctccatcc ggttgttgtc gggaaacact cgattccagt cattgactac
     6541 agttctgctt atttgtttct taacttttag cgctatcttg cctttatatc ttccgaaagt
     6601 acaccaatct ctcgaggaaa cgagtgaacc gatccgagaa tatcttaatg atgaagggct
     6661 ttatgacaca ctccatgagt atcaattaac cggaagtgca agaacaggct tcagtgagaa
     6721 tgatgaacag cttggtggac ctttatatga taatggcgaa gttgttttta cagcgaacca
     6781 aaaaggaaat ggctattgga agatcgaaaa taaaaatcat tacaccggtt ctggatggat
     6841 agaagatcag gacgcaccca tccaaccaat ccaagaattc cctgttgaca tcacgagcta
     6901 ccaaaccgtt atagaagaca aagaaaacat tacattgacc ctaaaaaaac aagttttctt
     6961 accttatcct tatggaaata ctaccttgac tgatttttca ttagctagtg gacaaacgct
     7021 ttactatttg cctgaaagcc agcgattcat tcctgtcccg aatgaatcga cacgttctgc
     7081 aactttacaa acagaaaggt tagtttttac gagagaagaa ttaaaaagca gtcagttaaa
     7141 agctgatgat ttagaaaatc agcagacaaa tcttcaattg ccaaaaagtt tgcctaaacg
     7201 tattgaggac ttggcggtcg aattgaccaa aaatgaagca actttaattc gtaaagtcga
     7261 agctgtctaa cagtatttaa aaacaagcgg aaatttccgc tattccaaaa cggataccgg
     7321 gcatactcca aaagaacacg attatgtgga ttatttcctc tttgattcaa aagtcggcta
     7381 ttgtgacaac ttttcaactt ctatggtcgt ccttcttcga acacttggta tcccagctcg
     7441 ctggacaaaa ggttttacaa atgggctcag aacaggcaca gataatcaag ggaatgagga
     7501 atacagcatt ctcaatagtc atgctcattc ttggccagag gtatactttc ctggatttgg
     7561 ctggcttcca tttgaaccaa ccccttcatt tgccaatcca atgggttcac aaccagttgc
     7621 tgaaacaacc gaaaccgtcc agcctgctat cgaacaacca aatgaaagcg aaaatatggc
     7681 agaaactatt tccagtgaga gatctgaggt cattccatca gaagaaacaa cactcacacc
     7741 agcttataaa atcgtcttat tcagccttgg agtgtgttta tccgtcttgt tgttctttct
     7801 attgttattc agaaaatctc tgcgctggac aagttatctt atctatcttc atttttttgc
     7861 ttctactaat acgattgcat atcaaaaact tcttaaccct ttggaaacat tggtaccgcg
     7921 caaacccgca gaatctttgc aggaatatag cctgcgaata gaacaagaat tcaagctaga
     7981 tctgcgtttc attcgattaa ctactcaata tgaagcagaa atatatggac gacaagcaga
     8041 tccggtaaaa ttcgataaaa aaacctattt agaaataacg catataataa gaaaaatggt
     8101 atacaaaaaa attctgacaa aagggagccg cttcaaaaaa taagataaaa tttctggaga
     8161 atctacttct ggaatgccga gaaccagctg attgagtatc gattactcga aaaaaaggtt
     8221 gtgacacgtt ttttgtcaca accttttttc attattatct gattttcaat gtcaaagcat
     8281 ttagagctac aactaccgta cttaacgaca tcaagacagc accaactgct ggacttaata
     8341 tgataccaat tggcgcaaga attccggctg ctagcggaat tgcaagaata ttgtaacctg
     8401 ccccccacca gaggttctgg atcattttct ttcgcgtttg cttggctaga tcaagaaaat
     8461 gcaaaatatc ttttggatcg ctgtttgtca atacgacatc cgcagaatcg attgcgatat
     8521 ctgtccctgc accgattgcc atcccgattg aagcacgggc taaacttggc gcatcattga
     8581 tcccatcacc caccatgatt acttttttcc cttggtcaag gtatttctgg acaacagctt
     8641 ctttatcatc tggtaataaa ccgccataat attcttcgat ccctaaataa tctgctactg
     8701 cttgggcagc gtttttattg tcaccagtaa gcatgacagg agtgattttt ctttctttca
     8761 atgttcggat aaattctttt gcttctgttt ttactacgtc acctaaagca acgattgcag
     8821 ctagatgatt ttctaaaatc aggaagctga tggtatttcc ttgttcttgg taaggtttca
     8881 ataatgcttg ttctacgttt aatccgagac gctcaacttc tttttcatta actattttca
     8941 cttgttgttt tttgactgtt gcctctagcc cgactcctga aagatttttt agattttcag
     9001 cttgataagg cttgatttca tgttctttca aataattcat aatgccaaca gccaatggat
     9061 gattggcatt cgcttccaag gctcctagat attgaaggat ttcattttta ttgaacgcat
     9121 catcaagtac ttcgacaccc gttacagtaa attttccttc tgttagtgtt cctgttttgt
     9181 ccagcatgat cacatctaga tcattggctt gctccagtgc attgcggttt ttcaaaagta
     9241 atccgttttt agctgctatt gatgtggaac gagcaacaac taatgggata gctaaaccta
     9301 gagcatgagg acaggcgatg ataaagactg ttaccatacg ttctaatgca ttaggaagat
     9361 ctgtcaagaa caaccaggcg atgaatgcca ggatacccac aattaatgcg acataaaaca
     9421 gccattttgc cactttgtca gataatgact ctagcttgga tttttctcct tgtgcttttc
     9481 gcaccatttc cataaccttc gctagataac cattttcacc agttccagtt acttcgattt
     9541 cgatcgttcc atccccattg atagaaccgc caatcacttt gtcattggct tgttttttga
     9601 ttcctcttga ttcgccagtc acagctgatt cgtcaacaat tgtttcacct ttcaagatta
     9661 caccatctgt tggcatttta tcaccagacc ggacgatcaa acgatcacct tcgtttactt
     9721 ctttcaatga aactgtctct tcttttccat ctttcgtcaa gcgtttcact gattctggca
     9781 gtaattctgc tagtttttgt aaagcattgc tggcattcga cacagcattc atttcaatcc
     9841 agtgacctag tagcataata acgatcaaag tagccaattc ccagaagaaa tccatgacgt
     9901 gtgtatgtgg attgagcaga tttgcgataa acgaatagac actataaata tatgcaactg
     9961 taatccccat cgcgatcagt gtcatcatag caggactttt ttgtttcaat tccatcttag
    10021 ctccacttaa aaatggctga ccgccataga taaatagtat agttgctaag atcaatacga
    10081 gccaatcaga accaggaaac gttacttgaa atggaaattc cattcccatc attggtgaaa
    10141 aaagaatgat tgggatagct aggataagcg atagccaaaa tttttgtttg aaattcccca
    10201 tgtgcatgga atgatccatg ccgccgtgtt cgtgatccat gtgcatcgaa tggtccattt
    10261 gtttgctgtt tgctatatct ccatggttat gtcccatgtg catggaatga tccatctgac
    10321 tatggtcatg tttcatctcc atctgttttt catgagattc tgtactttct ttgtttacta
    10381 cttctttttt atgctcatgt tttttctcca tatcgttccc attcattttt actccatccc
    10441 ttctcttact ttttcatgtg tcgatttaag cacagggagt tcaacaatac actgacggaa
    10501 ctaaacgcca tcgctcctcc tgcaatgatt ggattcaaaa agcctagtgc ggcaaaagga
    10561 ataccaatcg tattatagac aaaagcccag aaaagatttt gtttgatttt tctcaatgtc
    10621 aacctagaca actcgattgt ttgtgcaatg gatgccaaac tgctattcat cagcgtcaca
    10681 tcggctgttt ccatcgcaat gtccgttcca cttcccattg ccataccgac atcagctaat
    10741 gctaaggccg gtgcatcatt gattccatcg cctgccatac cgactttttt gccatctttc
    10801 tgaagttttt ctacgtaggc tgctttatcc tctggaagta cttcagcaaa gatatgcttt
    10861 ggatcaatac caacttgttt accaatcgtt tcggctgcca gtttgttgtc tcctgtcagc
    10921 ataaaaacat ctaatccttt attctggagc tgcttgattg cttgtttgac ttctagtttg
    10981 atttgatcag ccacggcaat caacccgatc acttgctttt catcagctaa aaacatgact
    11041 gtttttccct gctgttctaa ttctaacgcg tgttcttggt attcatcaaa tgataggttc
    11101 aattcaatta atcgtttacg tgtacccgca aaatagcgta ctccgttaat cgtaccgctg
    11161 attccagcac ctgggtgggc tgtaaaatca atcatatcgt atgttgctgc ttcttgcagt
    11221 tttccgtatt ccacgattgc tttacctagt ggatgttcag aagcttgttc taaagtataa
    11281 aaaatagata ggacttcttt agaaccgact agatctgtaa ctttgggctt tccttctgta
    11341 atcgttccag ttttatccaa aacaatgctg tctaagtgag cagctgcttc taatgcttct
    11401 ccgcctttaa ttaaaattcc atttcgtgca ccaacacccg ttcctaccat aatagctgtt
    11461 ggagtcgcta aacctaatgc acatggacac gcaatgacta atacagagac actatggatc
    11521 aatgcgagtt gccaatcacc agtgatcaaa cctgtagcta tgagcgtgat aaacgcgatg
    11581 actaatacga tcggaacaaa aatccctgag atccgatctg cgattttttg gattggggct
    11641 ttgctccctt gagcatcttc caccatttga atgatttgcg ctaatactgt ctgcttgccg
    11701 acttgtgtaa cttccatgtg aagtagacca ttcgtattga ttgtcccgcc aaagagcgtg
    11761 tcatccggat tcttttctac aggaagattt tcaccagtaa gcatactttc atctatcgca
    11821 ctgcttcctg aaataattcg accatctgct ggaatctgct caccaggacg gatgactagt
    11881 tgatcaccaa cgactacttc ttcaatcgct aacgtttctt ctttcccgtt tcttatcact
    11941 tgggcggttt ttgtttgaag agacatcaat tgtttgattg cattacctgt tttcgttttt
    12001 gctgtatgtt ccaaatattt gccgagcaaa atcagcgtga tgatcatact gctgctttca
    12061 aaataaagat cttgggggtg tccacggaaa aatccgttgt aaatgctcaa tgcaaaggca
    12121 gccgatgttc caattgctac caatacatcc atatttggtg ctttcgtctt gattgcatgg
    12181 tacgcacctt tataaaaacg agcaccgaca taaaattgga caggagcaga cagcactaac
    12241 tggacgattg gaaaatgaaa aaagtgaaca atcgccgcat ggcttcctaa catcatagca
    12301 atcattgaca acatcaacgg caaagtcaaa accgtactca atataagatc gaatagcatt
    12361 tttttcaaat acgcttgctt ttcttctgca attttttgtt tgtgggcttc atcgtacaaa
    12421 attgcaccat agccgatgtt ttctacgctt tggattaatt tttcagtggt cgtcccttca
    12481 tatttgacac ttgctttttc agtggccaag ttgactgtgg cattgaccac accaggttgt
    12541 ccgttcagct ctttttcgat cctagcagaa caatttgcac aagtcatacc tgtaatgacg
    12601 aacgtatcca ttttggtttc tgctgttgcc atcaaatcac ctctgcttta taacccaatc
    12661 cattgattgc ttgacaaatc ttttcggatt gaacttttgt ttcatcaaac ttgaccgtac
    12721 cgtttgcttt tttcaaattt actttcactt tttgcacgcc gtcaagtgcg cttactgttt
    12781 cttctactct tgctgcacaa tgattgcagc tcataccttc gattgaaaat tgttgtttca
    12841 ttttttcttc ctcctattga tgttgtttac attcacattg acctgggata cagttacatt
    12901 cgatcgtatc tactggttgc ttttgttcca gttgtttcaa aatctcattg atatcttctt
    12961 gagtcaaagt ggcttcttct actagatccg caatcgtctc tccaatcctt tttgcacaga
    13021 tatgggaaaa aagattttcc gtcgcactgc gaactgtttc catctccgag acagctggat
    13081 aataaatgaa tttttttcct tcttgttctg tccagatcac ttcttttttt accaaacgac
    13141 ccagcaaagt tttgatcgtt gctggtttcc aatccatcga atcagctaag atctgcgtga
    13201 tttcttgggc tgtcgtctgt ccaagtgtcc aaataacacg catgatctcc cactctgaat
    13261 cactgatctt tactggcgtt ttgacttttt ccatttattt cacacctttc gtttacaaat
    13321 gtaatcatta tcttatgaat acagattaca cttgtaaaca aaaactgtca attatttttg
    13381 ctctctattt tcaatttagt taaaaattct tgtttctctc gtcttgtttt aaggatgatc
    13441 agtttatttc ttgcattagc tacttggatc agctgctgta ttttcggttc attgttttct
    13501 tcaaaatgcc agataaaaga taaaaattct aagtattccc tgtttagttt ctccgaaaat
    13561 gattcaggca tatctggccg agattttttg tttatctttc tttttagaga acgccaaact
    13621 actcggtaga tggcgagata acgcggcact ttaagccaaa tgatcttatc tgcttcttta
    13681 atcctttcct ctaatgtaga agtataattt ccttcaacga tccatgacgg attagatacc
    13741 ataaacaatt gctgttcttg caaaaaccac ttttttgcct gaatactgta gtctgttgta
    13801 tgccataaaa ggtctagcgg cagtagcgga aagtcggtga tttctttgat cttccttgcg
    13861 agggtcgatt ttcccgaccc actttgtcca atcacgatga tcttcattct tctccctcac
    13921 ttctctttgg aatttggttc gatcatacca cttataacgc cgcaaaaaaa caagggactg
    13981 tgacaaaagt cgtgtcaaag tcccttgttt cgaataa
//
LOCUS       DAMEEU010000074        13813 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.075, whole genome shotgun sequence.
ACCESSION   DAMEEU010000074 DAMEEU010000000
VERSION     DAMEEU010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13813
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.075"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..216)
                     /locus_tag="PB779_002255"
     CDS             complement(<1..216)
                     /locus_tag="PB779_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739764.1"
                     /translation="MTIELEEHLLWFKYDPSEKFVKDLYKVWDTEVVFLAIETSLLVN
                     LHYSNKNYFKIPAVKTRMKKGVYFLFDI"
     gene            complement(743..815)
                     /locus_tag="PB779_002256"
     tRNA            complement(743..815)
                     /locus_tag="PB779_002256"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(780..782),aa:Lys,seq:ctt)
     gene            1196..1765
                     /locus_tag="PB779_002257"
     CDS             1196..1765
                     /locus_tag="PB779_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HDE0739765.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1752..2612
                     /locus_tag="PB779_002258"
     CDS             1752..2612
                     /locus_tag="PB779_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HDE0739766.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2802..3506
                     /locus_tag="PB779_002259"
     CDS             2802..3506
                     /locus_tag="PB779_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0739767.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            3511..5346
                     /gene="walK"
                     /locus_tag="PB779_002260"
     CDS             3511..5346
                     /gene="walK"
                     /locus_tag="PB779_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HDE0739768.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            5343..6659
                     /locus_tag="PB779_002261"
     CDS             5343..6659
                     /locus_tag="PB779_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739769.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            6660..7529
                     /locus_tag="PB779_002262"
     CDS             6660..7529
                     /locus_tag="PB779_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HDE0739770.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            7584..8393
                     /locus_tag="PB779_002263"
     CDS             7584..8393
                     /locus_tag="PB779_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDE0739771.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(8496..9125)
                     /locus_tag="PB779_002264"
     CDS             complement(8496..9125)
                     /locus_tag="PB779_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HDE0739772.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            9295..10587
                     /locus_tag="PB779_002265"
     CDS             9295..10587
                     /locus_tag="PB779_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739773.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(10663..11325)
                     /locus_tag="PB779_002266"
     CDS             complement(10663..11325)
                     /locus_tag="PB779_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HDE0739774.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            11550..11834
                     /gene="groES"
                     /locus_tag="PB779_002267"
     CDS             11550..11834
                     /gene="groES"
                     /locus_tag="PB779_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HDE0739775.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11885..13510
                     /gene="groL"
                     /locus_tag="PB779_002268"
     CDS             11885..13510
                     /gene="groL"
                     /locus_tag="PB779_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HDE0739776.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4626 a         2366 c         2937 g         3884 t
ORIGIN      
        1 gatatcaaac aaaaagtata cacccttctt cattctcgtt ttcacagcag gaattttaaa
       61 gtagttctta ttagaataat ggagattgac tagcaggcta gtttcaattg ctaaaaagac
      121 tacttcagta tcccagactt tatataaatc tttgacaaat ttttctgatg gatcgtattt
      181 aaaccaaagc agatgttcct ctagctcgat tgtcatgttt ttcacctcaa cgaaagtata
      241 cgaactaatg tttgttttgt aaaggataaa aatagggtag caaccggtac ccaaactagt
      301 acccatttat caaaaacgac gaaatttatg taaatagaaa aataagaata aacattgatg
      361 tatcaacatt tatatatctt tagaacaaat gaaaagggtg gttctcataa gaaaaacatg
      421 ttcgcacttc taggcaaacc aggatttgaa gaccttgcta aagaattgaa cgaacgcctg
      481 taaaataagg atttgtcgct agatttaaaa aatcagtgat agaaacatgt ttgctttaaa
      541 atgaaactag tgatagtttt agtgatagtg aacttaaaaa aagcactcaa tttgagtgct
      601 tttttattgt tattaaaaat taaaaaacta aaatacatac ccgaatttca tacccgaaat
      661 ataaaaaatg tcatcacgta catctttttc gaaactaccg aagtagccaa agatgtactg
      721 atgacgtggg tttggcaccc aatgggccgt gaggggctcg aacccgcgac ccgctgatta
      781 agagtcagct gctctaccaa ctgagctaac ggcccgtaca aaaagtactt aataatagta
      841 gcactaagaa ttttaaaatg caagactaca tttaaagaaa atcagaaaaa tctttacttc
      901 cttataggaa atcattcata gattattcac atttgctcgc tattatataa gcataccaac
      961 aaacaaagtt cttgcaagag aacaaaccct aacacttttt tcatttttta ctcctttccc
     1021 gccgtctccc cggcgggtct cctgttctta acgataaaag acaagaaggc ttagccttct
     1081 tgttttttgt tttcatggaa tcccgctaat caaatcacct agttaaagca actagattga
     1141 atgtttatca taagtctgat atcatgttta tgaaatgaaa aaaggagcgg ttatgatgga
     1201 aaaaatgcgt cagcaattaa tggagtgggg gaaggaacta gaaacattcc gtctgcctca
     1261 ctgggaagaa ctccctgact tagaacttta tatggaccaa gtcagaacgt tagttgatcg
     1321 ttatctttca cctgtgatac aaggagaaaa gcatccattg cttacctctt ctatggtaaa
     1381 caattacgtt aaactaggtt tgataccagc accagttaaa aaaagatata acaaagaaca
     1441 cgtagcattt ttacttgcaa tcactacgtt gaaacaagta ttgactattc ctgaaatcaa
     1501 agaagggata ttgttccaag gaaaaacagt aggaattcgt gaagcctata atctattttg
     1561 cgatgaacaa gaagcagctg tgtggatggt cagccaatta gcacaaggta aatctcatcc
     1621 gcaaaaattc gaccaggcaa cccctgtaga atatattgct gtaagagcgg caactttatc
     1681 gtttgcaatg aaacttcttg cggaaaaaac gattgttcta gaaaccgaat atttaaaaga
     1741 ggagaaaaca aatgaaaaac aataaaatcg caattttagt agattcaggt acggatgtgc
     1801 cagaagaatt gataaaaaaa tacgagatgt atatgatccc attgaaaatt atttataaag
     1861 atcaggtata tacagataaa attgacatta cctctgaaga gatctatcaa cgtttgccag
     1921 aggaaatccc tggtacatct ttgccggatg gtgagtcgat cacagaaatc tttgagcaaa
     1981 tcaaaaaaga cggttatgaa aaggtacttg cggtaacaat ttccagtgga ttgagcggga
     2041 catataatgt ggttcgttta attgcacaac agcaagaaga attggaagca tatgtactag
     2101 atacgaaaaa tattggtatt ggtgcaggtt tttctgcgat ccaagcagca aaatggctgg
     2161 aagaaggagt agaatgggat caactgatca gtaatctgaa tgagttagtc gaaagaacaa
     2221 aagttttctt taatgttgcg acattggaat atcttcaaaa aggtggacgg atcggtttag
     2281 ttgcttctat tgtaggaacc gctttaaagc ttaacccaat catctcatgt aatgaagaag
     2341 ggatttatta cacagtagga aaagctaggg gacgtaaaaa aagtttggat aaaacggttg
     2401 cttacgtcaa agaaaaaatc ggtaatgcaa aggtcttcaa cttagctgtt gcccatgggg
     2461 atgcgaaaga agaagcaatt gaaatggaag cgagacttaa aagagagttc ccacaagcaa
     2521 accaaatcta ctttggccag atttctccgg cattagtagt ccacactggt ccgggattat
     2581 tgggtgtcgg tgtacaagtt ttagaaggat aaatcaaaaa aaggaaacac tgaggtgaaa
     2641 atcagtgttt tcctttttta ttgaagttag aacaaaaaat aataaagtat tttgcacttt
     2701 cattttaatt ttctcttttg ttttataggc aaagatgaaa caaaagcaga aatacggtat
     2761 aatgagaagg tatgacaata atatataaga ggtggctctt tatgaaaaaa gttttagttg
     2821 tcgatgatga gaagccgatt tcggatatcg tcaaattcaa tttagccaaa gaaggctatg
     2881 atgtttatac tgcatatgat ggggaagaag ccttggaaaa agttgctgag gtagaacctg
     2941 atttgatttt acttgatttg atgctaccta aaatggacgg cttagaagtt gctcgtgagg
     3001 tacgcaaaac ttatgatatg ccgatcatta tggtaacagc caaagattct gaaattgata
     3061 aagtcctagg cttagagtta ggcgccgatg attacgtgac caagccattt tccaaccgag
     3121 aattagttgc acgtgtcaaa gcaaatcttc gtcgcggtgc cacggctgcg aaggaaccag
     3181 aagaggcagc acctgcggaa ttgacgattg gtgatttgac gatccatcca gaagcttaca
     3241 tggtgacgaa acgaggagaa acaatcgagt taacacatcg tgaattcgaa ctactctttt
     3301 acttggcgaa gcaccttgga caagtgatga caagagaaca tttattacaa acggtttggg
     3361 gttatgatta ttttggagat gtacgaacag tggatgtaac tgtacgtcgt ttgcgtgaaa
     3421 agatcgaaga taatccaagc catccaaatt atttagtgac acgtcgtggt gtcggttact
     3481 atttgcgtaa cccagaacag gagtaattgg atgaaaagaa aagtccgctt ttttcgatca
     3541 gtcaatttta agatcgctat tacctttatt ctgattttat tgatctcgat cgaaattatt
     3601 ggtgcctact ttatacgtgg tttagaacgt tccacgatca atacatttat taaagatatg
     3661 aatcaaacgg tggaatcatt agcaacaaca atcagcccgg aattgaatcg aaaagataat
     3721 gcagatgatg aagaggtaaa tgcgaatatc aaaagattta ttgaaaacag tgcgactagc
     3781 gatatcatcg aaatacgggt cgttgacgaa aaagggatca tccgaggaac aaccgatgtc
     3841 aatgaacaaa gcgctgtggg aaagaaaaat gattatgttg atatcaatga tttcacgact
     3901 aaacgttatg ttgctttaga taacgacgat aaacgggtga atatcaatgt tcaaccgatc
     3961 ctgtccccga ccggcgatgc cgttatcggg gctctttacg tcaaaagtaa tatcgaacaa
     4021 aaatattcgg aaatcaataa cacagcagtc attttcttta ctgcctcact aattgcggca
     4081 tttatttcaa tgatcgtatc tgttttagtt gctcgttcga ttacacagcc gatcggtgaa
     4141 atgagagaac aagccattcg aatcgctaga ggagactaca gtcggaaagt caaagtgcat
     4201 ggacaagatg aacttggaca gctggctgat accttcaatc agttagctga acgtattgaa
     4261 gaagctcaag atacaatgga agctgaacgc aatcgtttgg atagcgtgct atcccatatg
     4321 acagacggcg tcattgcgac agatcgcagg ggtaaagtca ttacgatcaa tgatatggct
     4381 gtttccttgc tagatatcaa aaacgaggaa gcaatcggac aatcgatttt gacactttta
     4441 gatatcgaag aagaatatac gttgcggaaa ttattagaag atccaaacga aatggtactt
     4501 gaccgttcaa ccagtacatt ggaaagtgat cagatgatct tgcgagtaga cttttctatg
     4561 atccgtcgcg aatcaggttt tatcagcgga ttagtagctg tcttgcatga tgtgacagaa
     4621 caagaaaaaa cagaacggga acgtcgtgaa ttcgtctcta atgtttccca tgaacttcgt
     4681 acaccgttga caagtatgcg tagttatatc gaagcattga gcgaaggtgc gtggaaagac
     4741 gaggaagtag caccaaattt tttgaaggta acgctagatg aaacagaccg aatgattcga
     4801 atgatcaatg acctcttaaa tctatctcgc atggatacag gtaataccca gcttcaatta
     4861 gaatatgtca atttcaacga gttagtgaat tttgttcttg accggtttga tatgatggtg
     4921 ggaaatcagg aaaaaaatta taagatccgt cgtgaattta cgcaaagaga tctttgggtc
     4981 gaagtagata cagataaaat catccaagta gtcgataata tcatgaataa cgcgatcaag
     5041 tattcaccag atgggggaac gattacttgt cgcttattag aaacgcataa taacgtggtt
     5101 ttaagtatca ccgatcaagg attggggatt cctaaaaaag atctgaaccg agtgttcgag
     5161 cggttctatc gagtagataa agcacgtgca agagcacaag gtgggacagg acttggatta
     5221 gctatttcta gagaagtgat taaggcgcat cgaggcgcta tttgggcaga gagcaaggaa
     5281 ggaaaagggt cgacttttta tatctcgctg ccatatgaac cttatgagga ggaatggtgg
     5341 gaatgagaat ctctgaaaaa gtcgttcgta taggactcat tttgatggtt gcgttaagca
     5401 tatacttctc ttatgcaatc tggctgagcc cagcaggaaa aagttcaatc aacgtagatg
     5461 agacaaacac tcaaatgatc gagtctcaaa gcaatcgaaa aacttccgaa gtctttcttc
     5521 cgcttcatgt tacatggcac cattcgggaa tgatccaaga aaccaacagt gaaaatctcg
     5581 tgtaccgatt gcaattgatc atcgataaag caagatttgg aaagctttct gaagtagttt
     5641 caggagacaa atcacagttt gaacaggtga aaaatctgaa ctctggtttt gagttggcct
     5701 ataatgcgcc ttttttgcta agagaataca aggaagcatt tgatttagat ttagatgtgt
     5761 cgaacttggc aaaagaaagc gaaaatatgt attttactag aatacaattc gatcaaggaa
     5821 ataaaaaaat ccgatttttg aattattcga accatctcgt atatgaagca aatatttcgt
     5881 tgaattggac agatatcaat aaagaattaa cagcaaaaga cacaaaatgg acagaaatga
     5941 caacagaacc atcgacgatc gacacgcaat atgctacgaa acattcgatc aaactgaaaa
     6001 agtatagtta tatcctgtca cagcaaccct atacactttt tagaaatgct tttttccaga
     6061 aaccagatag cgtgaaaaat aatgatgaaa gcaatgaatt gattttttac ggtgggaatg
     6121 aaacaatgtc tatccattcg gaaacgcaag tagttgattt tcgtggagag ctgccagaga
     6181 aaaaagaaaa tgctagtgta ttttctgaaa gtttccccta tattagcaaa ttaggcagtt
     6241 ctttagggaa cctcagatat tttgaccgca gtgacaatac gatcgattat cggatattcg
     6301 tggaaggctt cccggttttt gggacagaca gcagaggaca gattggtgtg gaagttggcg
     6361 gtgaaacgaa tggttctgtg caagtgaata tccaaaccag tttgaatacg attcaagtgc
     6421 cgataccttc agacgaagaa gtagaacttg caagtacgaa tgaaatcatc cagcagttaa
     6481 aagctaaggg agcagatagc aacaagattg gttcagtgat cgttggctat acatggcaaa
     6541 atgtcaaaga aacgaatcgt gtcgttgatc tcttacctga atggtatgtg aaatataaag
     6601 ataactggta ttcagctaac gaccttctgg aaaaattacc tggattggag gcgaattaat
     6661 tggatttcaa aaaaatcgaa tggatatttt tcgtcgcttt tttagggttg aatgtgtttt
     6721 tattcagcag ttatcatgac gcggtatacc aagaaaacaa tgtcattcgc tctaatcaga
     6781 ctgaatcaat ccaacaacgt ctggctagcg acgatatcac ttacacgggg aagatttcgt
     6841 ctgagaacaa gcaaggctat tatcttagcg cggagcagac caatcttagc acttcattag
     6901 cgaattatcg caaggctggt aaaagcggct tgctggcaag tggtgtgttt ttagacggtg
     6961 atgttttgac gaaatcttta tccagttcag atgctgaaaa gaacgtgatc gatccagata
     7021 aaattagtag ttccttggaa gattttttat ctaacaaaga caatatttta ttcggtaatg
     7081 attatgtgta cacgaaaaac ttttctcatt tagaagaaga accactagaa atccaagcaa
     7141 gccaagagta tgaaggcatc ccattcaatg atgatacagc aaaaatcgtt ctttctttag
     7201 aaaaaaacga taatgattat agcatcacga aatacatgca gacgcattta tctgatatcg
     7261 agcagctgcg cgaaaagacg gaactgtata cggaagagga agcaatcaat acattgtaca
     7321 tcaataacaa aataccaaga ggatcaaaaa ttttatggcg tcagctagct tattcctgta
     7381 ttctgaaagt ccgggaaaaa aatgtgtatg ttcctgtttg gcatgtagcg atcgaaacaa
     7441 gcgataaagt ggtccaaatt gagagtgtca acgctttcag caatacgatc gtgacaaaca
     7501 atactgtacc aaaagtggaa gatcaataaa aaagcgagta taatgaaaaa agtttacaaa
     7561 gtaagaaggg aagtaggagt caaatggctg aagaaaaacc agcttttaaa atcagtatcc
     7621 tagcaagtgg aagttcgggt aattcacttt atatcgaaag tgaaaaaaaa cggcttttgg
     7681 tcgatgcagg acttagcggt aaaaaaatca cttccttgat ggctcaaatt gatcggacac
     7741 cggaccaatt agatggaata cttgtgacgc atgaacatcg agatcatata catggcgtgg
     7801 gtgtcttggc tcgtaagtat catttggatg tttttgccaa tcagcagact tgggaagcga
     7861 tggaaccact gattggaaat gtaccagtgg aacaaaaaca tctatttgag atggggaaag
     7921 tcagaacatt cggcgatatc gatattgaga gtttcggcgt ctcccatgac gcagcggctc
     7981 cgcaatttta tcgtttccat aaagaaaatc ggtcattcgt catgttgacg gacaccggat
     8041 attgcagtga ttatatgcga ggtgtcattg aaaatgccga tggttatttg atggaaagta
     8101 atcatgatct tgagatgtta cgcatgggac cttatccgtg gaatttaaaa cagcgtattt
     8161 taggagatag aggacatctt tccaacgaag acggtgcact tgtcatgact gatgtgatcg
     8221 gtaatcggac caaacgaatc tatcttggcc atcttagcaa ggaaaacaat atgaaagaac
     8281 ttgctcattt aacaatggaa aatgttttga aagaaaaaga ttttggcgtt ggacatgatt
     8341 ttgaaatcta tgatacagat ccagatgaag caactgagct attttcgatt taaacagttc
     8401 aatcaataaa aatataaaaa gcagaagata aaatcaatca gggttggttt tatcttctat
     8461 ttttattttt ttagcatatt aaaaaaataa ccgtattatc gactgactac actgatgtgc
     8521 tgcttttcat gtttctcatc cagtatctca tctactaatg caatcgcgta atctgccatg
     8581 ctgatcgtac tgtcgccagc agcgtttctt tgtaaataat catcacttaa caaataagta
     8641 cctgtacgtt tgccatgtgg atcaaataaa gaagctggac tgatataagt ccaatgtaga
     8701 tttttagatt gtttcaattt taacaatcct tcgtacatat tgaaagctgt tggatagaag
     8761 ggtgcatttt taggtacttg gtcaatcata cgagtcgtct tttctgtatc taagaataac
     8821 gaagaggcac ccccaacgac aattaagcgt gtatcggttc cttcaagcat ctcaatcaaa
     8881 tgggacaaag aagtttgatg catttcttct tttcctttgg gagcgttgaa agcatcaacg
     8941 acaacatcaa aagatgcaag atcagtagtt gtcaactcaa ataaatcctt ttgtataaac
     9001 ggaacatctg atggcaattt ttctggatga cgcacgattg ccgtcacgtc taaatctctg
     9061 gacaatgctt cgtctaaaat aaatgaacct gcatggccag tagctccaat gagtgcaatt
     9121 ttcataaaaa acctcctttt ttattcctgt ccattgtaag cagttgctga atattcgtca
     9181 aagaatccga tttttgaaaa gctcagtgcg cattcctttc atggttcgtg atcattgggt
     9241 atagttaaat taagaaaact gattgataaa aatagaagtt gaaggagata agaaatgaaa
     9301 gagtggttag atcgtgcctt tttaccaatg ataacatctg ttgtgaatct tagaccctta
     9361 actgctttgc gtaatggaat gacttacacg atcccaataa ttattgttgg ctcgctgttt
     9421 ttcttatttg ctcattttcc tgtggattac atcgctcagt ggatagacaa aacaggattt
     9481 tctatgtatt ttacacaagt ataccaggct acatttgatg tgatagcctt ttggatcgtt
     9541 tttgccattg catacgctta tgcaaaagaa gaagacatcg atcgcttacc agtcggcata
     9601 acagccttgt ctgcttatct actgcttatt cagccactaa atactcagat agatactgtc
     9661 tggacaggtg ctgaagggat actaggagca gttacaactg ggctcatcat cggatggggc
     9721 tatgcacgtt tagtaagact tgcgaaaggg tggaagcaaa gagagaagat acctgaaaat
     9781 gtttggcagt cttttacttc attgattcca atcattgtta tagtcacttt tacgcttatc
     9841 ggttcagcgg tttttcaaca gttgttcaga atgactgttg ttcaaggagt atggacatat
     9901 gtccagcttc ccattcaatc gttcatagac acgttgtttg gtgtgctttt attaggtttt
     9961 tttgttccgt ttttatggtt atttggtctt catggatctg cgatggtcaa tgggttggtt
    10021 agtcccgtct tgcaagcgaa ttcattagcg aatgcagaaa tcttagcctc aggacaagag
    10081 ttgacggtgg caaatggcgg acatatcgtt actcagcaat ttctcgatca gttcatgacg
    10141 gttacgggtg ctggattgac gttaggggct gtatttttta tgacggtttt tgcgaaatcg
    10201 aagaaataca gagaattagg aaatcttgct cttttaccag cctttttcaa catcaatgaa
    10261 tcaattattt tttccacacc gatcgtgatg aacccgatga tggctgttcc ttttattttc
    10321 gcaccggtcg tttcaggatt gattacctat tccgctttat attttggatt cgttccttta
    10381 tttacagcag tccaagtccc ttggacaaca ccgccgatcc tctcgggttt cttagtaggc
    10441 ggagtgcctg cagcgatttt acaaggtatc gtgttgtcaa ttagtttttt catttatttc
    10501 ccatttttga aaaaaataga ttctgcaaac tgcaaaaagg aaagacagac aaaaaatgat
    10561 ggagcagcag aaaagatgaa cgactaaaaa acaaaaatac tcctgtcgct ttagattggg
    10621 aaaatcacca atctaggatg acaggagtat ttatagtcat gtttatacta gccctttttg
    10681 gacagctaat tgaacaagaa caactaatgt gttcattcct acgtgtgtga tcatcgatgt
    10741 ccagatccga ccagttgctt tgtactctag gctgaagaag aaacctagga aaaagtagat
    10801 tagcagatga ccatcattat gagcaaacgc aaacagcaaa gagctgatca ctgctccgac
    10861 ccaaaaattt gaatatcgac tgatgatccc cagtatactg cggcggaata cgaactcttc
    10921 catgatgggt ccagcaacag ttgtcgccaa aataaaagcg ggtgcttcca tgatcatctg
    10981 gatgatattt tgtgtattct cggaaggggt tgctttgcca aacaatacag attctaacat
    11041 gacagcgatg ctttgcagaa tcaatgcgac aaagattcca accaatccat aaataacaat
    11101 ctttggagca gaagcttttt ttaccgctga ttcgatcgct aagggttcac gttgcttaaa
    11161 ataaaaaata gctaggacaa cggcgcctag tatatacatg actgcagttg ctgtgatcaa
    11221 ttcagacgta gattttacaa gtcctatcga agctaggatc aagggtgaga taaaaattag
    11281 accatagcaa aaaatgctga ggaagctata tttttttaaa gacatgtaat tcctcctttt
    11341 aagggataac aagcatgcaa ggcaagctta tatcgattga tttcaattat atcataattt
    11401 caataagcag ctgtcagaat aaaatttctt ttctttgatt taaaagcttg caaaaaagag
    11461 ggagaatgag tattattaaa aatgtaggtt agcactcgaa ggttaagagt gctaacagat
    11521 taaaaaaaga gttatcggag ggatttatcg tgttaaaacc attaggtgat cgcgtcatta
    11581 tcgaagtcgc aaaagaagaa gaaaaaactg tcggaggaat cgttttagct tctgctgcta
    11641 aagagaaacc ccaaactggg acagttgttg cagtcggtga aggccgtttg ttagaaaacg
    11701 gtgaaaaagt tcctgccgct gtaaaagcag gcgaccaagt tatgttcgaa aaatacgccg
    11761 gtacagaagt aaaatacgaa ggaaaagaat atctgatcgt cgcaggaaaa gatatcatgg
    11821 cgattgttga gtaaatttgg aagataaaaa aataatcaaa aataatcaat gaggtgaatc
    11881 aatcatggca aaagaattga aatttgcaga agacgcacgc gcagctatgt tacgcggggt
    11941 agataaatta gcagatacag tgaaagtaac attaggacct aaaggccgaa atgtcgtact
    12001 agaaaaatct tacggctctc cattgatcac aaatgatggt gtgacgatcg caaaagaaat
    12061 cgaattagaa gatcattttg aaaacatggg tgcaaaactt gtatcagaag tagcatcaaa
    12121 aacaaatgat attgcaggag acggtacaac gacagcaact gttctgacac aagcaatcgt
    12181 tcgcgaaggt ttaaaaaacg taactgcagg tgctaatcct ctaggcattc gtcgcgggat
    12241 cgaattggca acaaaagcag cagtcgaaga attgcataat atctcaactg ttgttgattc
    12301 aaaagaagcc attgcacaag tagcagctgt ttcttcgggt tctgataaag ttggacattt
    12361 gattgctgat gcaatggaaa aagttggaaa cgacggtgtc atcacaatcg aagaatcaaa
    12421 agggatcgaa acagaactag atgttgtaga aggtatgcag tttgatcgtg gttacttatc
    12481 acaatatatg gtaacagata acgacaaaat ggaagctgtt ctagaaaacc catatatctt
    12541 gatcacagac aaaaaaatct ctaacatcca agatattctg ccattgttag aacaaatctt
    12601 gcaacaatca cgtccattgt tgattattgc tgacgatgta gatggtgaag cattgccaac
    12661 tcttgtattg aacaaaatcc gtggaacatt caacgtagta gctgtaaaag ctcctggttt
    12721 cggcgatcgt cgtaaagcaa tgcttgaaga tatcgctatt ttgacaggtg gtacagtaat
    12781 tactgacgat ctaggtttag aattgaaaga tgtaacaatc gaaaacttag gaaatgcttc
    12841 taaagttgtt gtagataaag acaatacaac gatcgtagaa ggttctggag aaaaagaagc
    12901 aatcgaagct cgtgtgcaat tgatcaaaaa ccaaattgct gaaacaactt ctgattttga
    12961 ccgcgaaaaa ttacaagaac gcttagctaa attagcaggt ggtgtagctg ttgttaaagt
    13021 tggtgcagct actgaaacag aattgaaaga attaaaatta cgcattgaag atgcattgaa
    13081 tgctacacgt gccgcagtag aagaaggaat ggtctcaggt ggtggtacag ctctagtgaa
    13141 cgttatcagc aaagtttctg ctgtagaagc agaaggagac gtggcaacag gtatcaagat
    13201 cgttgttcgt gctttagaag aaccaattcg tcaaatcgct gaaaacgctg gttatgaagg
    13261 atcagtgatt gttgataaat tgaagaacgt ggaactaggc actggtttca atgctgctac
    13321 tggagaatgg gtaaacatgg ttgaagcagg tatcgtagac ccaactaaag taacacgttc
    13381 tgccttgcaa aatgccgctt ccgtttctgc cttgttatta acgacagaag cagtcgttgc
    13441 agataaacca gaaccagcag cgccagcagc tcctgcaatg gatccatcaa tgatgggcgg
    13501 tatgatgtaa gaaaaagcaa cttgcttatc tacaactgat cattagtgaa agacagataa
    13561 aaagaggctg gaacagaagc gtttaactcc aagaaataag aagaaattca cggaaattgc
    13621 ttttcaaatt tttgtgaatt tcagcttatt tccgaaggag ttgcttctgc ttccgctgtt
    13681 tatacgtgtt tagagcgtga gacaaaagtg ttctttactt ttgtcccacg ctcttttttg
    13741 tgtgtaatta taatgaaaat agttattttt aatagttata atattttatc tattaaaagt
    13801 aaatatccat tca
//
LOCUS       DAMEEU010000075        13616 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.076, whole genome shotgun sequence.
ACCESSION   DAMEEU010000075 DAMEEU010000000
VERSION     DAMEEU010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 13616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.076"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            19..1446
                     /locus_tag="PB779_002269"
     CDS             19..1446
                     /locus_tag="PB779_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739777.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(1538..1903)
                     /locus_tag="PB779_002270"
     CDS             complement(1538..1903)
                     /locus_tag="PB779_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDE0739778.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(1900..2265)
                     /locus_tag="PB779_002271"
     CDS             complement(1900..2265)
                     /locus_tag="PB779_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HDE0739779.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(2457..2705)
                     /locus_tag="PB779_002272"
     CDS             complement(2457..2705)
                     /locus_tag="PB779_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739780.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            2704..2832
                     /locus_tag="PB779_002273"
     CDS             2704..2832
                     /locus_tag="PB779_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HDE0739781.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            2889..4583
                     /locus_tag="PB779_002274"
     CDS             2889..4583
                     /locus_tag="PB779_002274"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HDE0739782.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            4587..4706
                     /locus_tag="PB779_002275"
                     /pseudo
     CDS             4587..4706
                     /locus_tag="PB779_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349726.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
     gene            4683..4979
                     /locus_tag="PB779_002276"
     CDS             4683..4979
                     /locus_tag="PB779_002276"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739783.1"
                     /translation="MQAFEHRLPRGCEKAALHQVIRTPKLKLLLMFLTWLDLLPQMQA
                     FEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQAFEHRLPRGYEKGV"
     gene            5357..6490
                     /locus_tag="PB779_002277"
     CDS             5357..6490
                     /locus_tag="PB779_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HDE0739784.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            6521..6841
                     /locus_tag="PB779_002278"
     CDS             6521..6841
                     /locus_tag="PB779_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HDE0739785.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(6870..7334)
                     /locus_tag="PB779_002279"
     CDS             complement(6870..7334)
                     /locus_tag="PB779_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739786.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(7465..8718)
                     /locus_tag="PB779_002280"
     CDS             complement(7465..8718)
                     /locus_tag="PB779_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739787.1"
                     /translation="MDKFVAFMEKHFIPVASKIGAQRHLVAIRDSFMVSMPLMILGAL
                     AVMINNLPIPGFQELMNSIFGGESWKGFGAAAWNGTFAILSVLIAFLLAYHLANGYRK
                     DGVSAGVISLGSFFALGGALGMSSNGLFIAIIVGIISTEIFVRLSGNEKLIIKMPDGV
                     PPAVAKAFASLLPAMITISAFALVAAIFAAFGVDDIVGSFYTVVQEPFMGLANSYPSA
                     LLLAFITPFLWFFGLHGANMVDPLMQTINAPAIEANVNAIAAGHSAPFIVNKPFFDSF
                     VNLGGTGATLGLLLAIYLVGRKNKPYMVVTNLSIAPGVFNINEPTMFGLPIVLNPIMF
                     IPFILTPMVLVSVAYFATSTGLVPAATVMPPWVTPPIIGGVLATKSIAGGVLAAVNLV
                     LSILIYLPFVKVATIQERRKEALDA"
     gene            complement(8747..9064)
                     /locus_tag="PB779_002281"
     CDS             complement(8747..9064)
                     /locus_tag="PB779_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HDE0739788.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(9090..9410)
                     /locus_tag="PB779_002282"
     CDS             complement(9090..9410)
                     /locus_tag="PB779_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739789.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(9874..11289)
                     /locus_tag="PB779_002283"
     CDS             complement(9874..11289)
                     /locus_tag="PB779_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0739790.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(11306..12622)
                     /locus_tag="PB779_002284"
     CDS             complement(11306..12622)
                     /locus_tag="PB779_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739791.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(12772..13470)
                     /locus_tag="PB779_002285"
     CDS             complement(12772..13470)
                     /locus_tag="PB779_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HDE0739792.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
BASE COUNT         4314 a         2772 c         2349 g         4181 t
ORIGIN      
        1 caaggcggag gctctactat gattgaagaa tatattgaga aaaatatttt aagacagctg
       61 tttttatgtg ggcaattcta tgtaaataaa gaagtcaatc tagaaaagct ctccaatctc
      121 ctgcatgttt gcaaaaccac tttactcaat gatatcaata acataaaaaa agaatttgaa
      181 gaacagatcg cttatacaca tcgggaaaag gaccgttaca ctttatattt ttcagaacat
      241 atacctcgat gcaagatcat gcagcaattg tctcaaaatt cgttgttttt aaaaacttgt
      301 ctgctttatt tggaagaaga tgaacctgat tatcttcaat taactgaatg tgaattcatc
      361 tctgtcagca aagcttattc attaaaaaaa caagtattag cttattttaa tgactgcggg
      421 atcgaaatcg accgctactc ccctcgattc actgaaatgg aaagacgtct gctgcttctt
      481 aatgtgtcgt atcgtttagg cggttttaat tcttgggagc tacctgaatc gttttttgaa
      541 cgtgccgatc gtttcattga atccgtaacg gaaaatagtg gcagatttta tgataaagaa
      601 aataaagaaa tcttatcgat tggttttgct atcagtttcc tacgccagca agtgtgtgct
      661 gtgacaatag attcaaaatt tatcgaagaa atcaaaaaac gtcctattta caattatgtc
      721 gaatcagcat gggaaaacac tgatttccaa acctattata aaaaagaaga attcgccttt
      781 attttgacac tattcaatct ttgtaattat ggtttccatt cttatcagtt gattgcggaa
      841 gactttcaac agctacacca agtgtttatt gacaatactc ccgaaataaa agaactagtt
      901 gctacctttg aatctcactt caatcaagaa ttattcggaa accaaccgtt cgaacgtgcg
      961 ctgattcatc tgatgcgttc ggcttgggat aactatcaat tattcatgcc agaaaaattt
     1021 tatcttttaa atgaggaaca gacaaattta tataaagaag tccagacaat tttttccagc
     1081 tggtccagcc agttacctta tgatctacgg ttgaatccta attgcatgcg ggcttttgtg
     1141 atcgaattga gcggaattct ccgtctgaca aaagaacatc tgactatcta tatcgtcaca
     1201 aattcggatg ttcattatct gatttatcgg gaagccttgg aagctgtaac tactttcgat
     1261 tttcaagttg caccaacaat ttattcaagt atatctgata taaagaagta tgcgcagcag
     1321 tcctcaaacc gggtattatg tgaacgtaca ttatatacac cagatgcggt ccaatatgaa
     1381 aatattattc ctatttcgat caatacgatc gatcgagcta tcatttcagc tgtgcaaaac
     1441 aaataagggg ctgtgacaaa aatcatgtca cagcctctta tttgttgaag atgcccattt
     1501 ctgtaacaat ctcttgatac acgtcaggct cacaacctca cttattttgg acatctacgg
     1561 gtccgatctc tttatttaaa aaataagaaa tgatggttcg gataactacc aacgccgcta
     1621 gttggaaaat atcctgcaag gtaggtttga taatcgattc gatgatccca gctgaaacaa
     1681 gaatttccaa acttagaagt atatagcctc ccaacatctt tttaatagca ttgttctcgc
     1741 tgactcggtc gctttgcact tttgtatgga caaataaata tttcaaaaaa tccttgattg
     1801 atagacaaac accccaaacc aataaacaga tagcaaagat atcaagtccc agtacaagtt
     1861 tttcgaaata tggaagaaga aactgcatca actctgtcgt catcctacct ctcctcttct
     1921 ttgtttttct ttgtcttcta tttcctgatt caagaaataa gaaatgactg ttcgaatgat
     1981 aataataagt gcaagcttca aaatatctgt ccaagtcggc ttgataactg actcgatgat
     2041 atcagcaacg actagtactt ccaagcttaa caaaatataa cttgctagca gttttcttgt
     2101 atctgcatta cgagtattac gttctgcata gtttttcttg acatgagacc aatcaaaaag
     2161 tttgaataga acaagaacga tcccgacaat taagataccg atagaacaaa tatttaaaat
     2221 agcaatgatc cattctagaa attcaattaa atttgagcga aacatatacg ctacctactt
     2281 tcttttaatt tgttcctatt cttttattgt aaaagaaagt taccttgttc gtctatttaa
     2341 aagttgttct aatgataacg gttcgcttaa atttttcttt ttcactctcc catttttctc
     2401 cctccatcca taaatcgtgg aagtatccaa aacaacgtag caagttaaaa taaggcttag
     2461 tccgtcatca gcttttcaaa gaagcactgt ctcggtgctt tttttgtacc caaatttcta
     2521 aaaatagaac catacacctc ctcaaatctt ttcttcttac ctaccctatt tttatttaca
     2581 ggaaaatcag acacttcttc ttttttgtca aaatttcctt tttcttctcg tcctatcatt
     2641 tggcattcta ataaaaacga actatccttg gatatagaaa gagaaaacaa ggaggcgttt
     2701 ttcatgagta aaaaattaat caaagtcggc atcggtttag gtttgcttgc ccttggcgct
     2761 gcatatctag gaaaaaagac aggactattc gaagatgaca gtcatttata tgatgaattc
     2821 gaatcaatct agcatcctat ttagttgaat cactacggac atacttggaa gacattggag
     2881 gaatcacaat gagaaaaagt aaagcaataa tgattggtgc cggtattgcc aatatggcag
     2941 cggctgttta tttgattcaa gaaggcaaat ggaaagggga tcagatcacc ttttattcat
     3001 tggatgatca cggttcaaat gatggtgcac cgaccgacac tgtagtggat gaatattgga
     3061 ataaaaacca tccattagaa aaccaaaaag gctatattgc tcgaggcggt cgcatgctta
     3121 attaccgtac ctatgtagat ttgatggatc tgttaagtcg aataccttct gttactgagc
     3181 cagggatgac tgctgaagaa gatacgagag attttgatgc aaaacaccga acctttgaca
     3241 aagcacgttt gatggaaggt ggcaaaggaa tcattgatgg cggaaaactg ggattcaata
     3301 ataaagaccg tattcttctg actaaactga ttgctatgcc tgattcagaa gaagaaaaac
     3361 tagacaatat cactatcgaa gaatatttca aagatgatcc acactttttt gaaacaaact
     3421 tctggtttat gtgggaaaca acatttgctt tcagaacacg tagttctgct caagaattgc
     3481 gtcgctatat gcatcaaatg atttatgaat tcactcaaat cgaacatcta gtgggcgtca
     3541 atcgaacacg ttacaatcaa tacgaaagta ttatgcttcc tttgatcgag tacttgaaag
     3601 aacaaggatg caaaatcatt ttgaaccgcc gtgtcactga ctgggaattc aaagaaacac
     3661 cgatgcaaga tgaaatcact gtgactggtt tgaaaattac caatacactg actcaagaag
     3721 aagaatacgt tgtggtcgat gaagatacag cagttatttt cactaatggg tccattacag
     3781 attcagctac tttaggagat tacgaaacac cagctgtaga aaatatggat tatggtgcag
     3841 cttctagtct ctggaaaaaa gccagtgaac gtttctacaa cttgggaaat cctgacaaat
     3901 tctttgctga tcgagatgca agcgaatggg tcagctttac cctgacgacg aaaaaccatt
     3961 tgttgttgaa tgaaatcacc cgtatcacga ctcaagaacc aggaaatgcc ttgaattcat
     4021 ttatttcaac cacaccgatc acgccgttag gccaaaaaga tgtcaatatg tctatcgtcg
     4081 tgcatcatca accgcatttt acgtctcaga aaccaaatga aacagttatt tggggttatt
     4141 tcctttatcc aagacgacgt ggcgaatttg tggataaaca gtatattaaa atgaatggaa
     4201 aagaaatgct agaagaactg attggacaac tttcaaaagt agatcctgga ccagtgaata
     4261 ttcgtgaaaa agaaacagaa attttcgaca gcgtaataaa taatatccct gtctatatgc
     4321 cttatgcttc cgcgttgttc aataatcgtg ccaaaagcga tcgaccaaaa gtcattccta
     4381 aacattcgac caatctggcc tttacaggag aatttgtcga gcagccttat cagatgatct
     4441 ttactgaaca aagtgctgta cgttctggag aaatcgctgc tttccatttt gcgggtattc
     4501 ctatgtcccg tcttgtcaaa acaccgcgtt acgacaaaga tattcctact ctagctcgtg
     4561 ccgcaaaaaa aatgtttgaa taatcaagag gttgtgaaaa agctgccctg catcaagtaa
     4621 taagaacaac caggctaaaa cagcttctta tgtttttgat ttggttggac ttattaccgc
     4681 agatgcaagc ttttgaacac cgtttaccaa gaggttgtga aaaagctgcc ctgcatcaag
     4741 taataagaac acccaagcta aaactgcttc ttatgttttt gacttggttg gacttattac
     4801 cgcagatgca agcttttgaa caccatttac caagaggtta tgaaaaagct gccctgcatc
     4861 aagtaataag agcagccaag ctaaaacagc ttcttatgtt tttgacttgg ttagacttat
     4921 taccgcagat gcaagctttt gaacaccgtt taccaagagg ttatgaaaaa ggcgtttagt
     4981 ttcgagtatg aagaaaaatt ttgtgaaaat ggttcctcac gtttttgcat aaatttgact
     5041 taataccgag aaactgatcc cttctgtcat aacctctttt tatttatgtc tgtttctttt
     5101 tgaaaacaac tattttttca acgtttactc tcttgccaat ccaacatcat ctaacggata
     5161 caactatttc aatgattacc attacactaa aaaatcggaa acacacctct ccgaacacaa
     5221 atacataaga ctatagaatg tttcatttaa gaaaaaaagc gtttcattat caaaaaggta
     5281 agatctcctt taaaatgaaa ttatctgtag tactaataat gcagacaatt ttatgaatct
     5341 gaaaggagca tctccaatga aagcagtcac ttggcaagga aaacagaaaa tggaaatcag
     5401 aaacgtagat gatccaaaaa tattagaacc aacagatgca atcatccgta tcacagcaac
     5461 agccatttgc ggctccgatc tgcatcttta ccatcatggt gaagcagttt tggaaaaagg
     5521 gtatgttgta ggacacgaac caatgggaat cgttgaagaa gtgggatctc aagttcaaac
     5581 attgaaaaaa gggcaacgtg tggttatccc ttttaatatt agttgtggtc attgtcattt
     5641 ctgcctgaat cacatggaaa gccaatgtga tgaatcaaat ccagatcagt tatatggcgg
     5701 gcttttcgga tttggcaagt tgaacggtaa tcattggggt ggtcaagcgg aatatctaag
     5761 agttccttat gcagactcta cttcatttgt tgtaccagat aatgatcttc ctgatgaaaa
     5821 agttttattt ctatcagata ttttgcccac agcttattgg agcgttgaaa acgcaggagt
     5881 aaaaaaaggc gatacagttg tgattctagg ttctggtcca gtcggtctat tcgctcaaaa
     5941 attcgctgtt atggctggag cagagcgcgt aatcgcagta gatccagtac agcaccgtct
     6001 agataaagcg gctaattaca atggggttga aacttatttc ttagaagaca cggcacaagc
     6061 tggaacagaa ttgtatgaac tggctaaagg tggcgcagat gtcattatcg attgtgtagg
     6121 aatggacgga ttagagcctg tcaaagaaaa agcgaaaaat ttagtaagct tacaaagcgg
     6181 cacaatctct ccattacaga tggcatcgca agctgtcaaa aaatttggaa cagtccaagt
     6241 aactggtgtt tatatgactc cagcttcttc ttacccgctg caagaatttt ttatgcggga
     6301 tatcgctgtc aagcatggac aggcaccaat tatccatcta atgccaaaaa tttacgcaat
     6361 gattgcagaa ggactattcg atcctacaca aatcattact cattcgctgc cactatcaga
     6421 agcagcacaa gcatatgaga tctttgacaa aaaagaagat aaaaatataa aagttgtttt
     6481 gaaaccttga attcagtaaa aaatacaggt gattttcttt atgcccaaaa tcaaacgaaa
     6541 tacccatgag atcgaaatag gaaaagaaga agatatcgaa atacgaggac gtcgcttccg
     6601 cttctatttc caaaatcgtt acacattgat ctcactggct gtcgatttat taaccgggat
     6661 tttctatatt tttggaagcc ttgcttcctt aactaaaatc cccgatcgat atggcaccta
     6721 tttttatttg gctggtgcta ttttcttgac gattcgtcct attctcagaa tcgtaaggaa
     6781 catttttatt tacgacgaaa aaaaagcaat gaagagaaca agcaaaaaaa aagaggcatg
     6841 agaatttttc aaatctcatg cctctttttt caccctatcg tatcactttg atacagacga
     6901 gcggtcgtcc cactttcttc cttgaccatt gtcaaaaatg tccactcgta tcgttcataa
     6961 aacgtggtat gatctgtaat taagtaaagt ttttcgtacc caagttgatg catttctttt
     7021 ctgatttccg ctaatatccg cttggctatc ccctgcttac gcttttccgg ttcaacaaac
     7081 agggcacaaa gatttggtgt cagatcaggg cggttatgga agtcgttttc aatgacgccc
     7141 gctcctccga cgatggtttc tttttcatct aagaccacat accattgagg aatactttcc
     7201 ttattagcga ttccagtacg aatactttcc tcatacacaa cagcaggaac tccccatttt
     7261 gatgaaaacc aattcgcgct ttgttttact aattctgggt gttctcttaa tttgatccag
     7321 ttatatgtaa ccaatgttta aacctccgac taaaataaaa cgtttacaaa aattatacaa
     7381 gtctttatga aaattagcaa tgacaacaat agtgatgtaa aaaaaaaacg gaaaacaatc
     7441 acttgttctc cgttttttga ttaatcaagc atctaaagct tcttttcttc tttcttggat
     7501 cgtagctacc ttgacgaacg gtagatagat caaaatagaa agaaccaaat tgacagcggc
     7561 tagtacacca cctgcaatac tttttgttgc caatacaccg ccaataattg gtggagttac
     7621 ccatggaggc ataacggtag ctgctggcac taaacctgta gaagtcgcaa agtaagcaac
     7681 actaactaag accattggtg tcaaaataaa tggaatgaac atgatcgggt tcaacacgat
     7741 aggtaaccca aacatcgttg gttcattaat attgaagaca cctggcgcaa tcgacaagtt
     7801 tgttacaacc atatatggtt tgtttttacg tcctactaaa taaatagcta acagtaaacc
     7861 taaagttgca cctgttcctc ctaagttgac aaagctgtca aagaaaggtt tgttcacgat
     7921 aaacggtgcg ctatgcccag ctgcgattgc attaacgttt gcttcaatgg ctggcgcatt
     7981 gattgtttgc atcaaaggat cgaccatatt cgctccgtgt aaaccaaaga accataagaa
     8041 tggtgtgata aatgcaagca gtaaggcaga tggataagag tttgcaagtc ccataaatgg
     8101 ttcttggacc actgtataga aagaacctac gatatcatca acaccgaatg cagcaaaaat
     8161 tgcagcaact aaagcaaacg cagagatagt gatcattgct ggtagtaatg aagcaaatgc
     8221 ttttgcaact gccggtggca caccatcagg cattttgatg atcaattttt catttccgct
     8281 taaacgtaca aagatttctg ttgaaataat cccaacaata atagcaataa acaaaccgtt
     8341 tgagctcata cctaatgctc cgcctaaagc gaagaaagag cctaaagaaa tcacacctgc
     8401 ggaaacaccg tcttttcggt agccgttagc taaatgataa gcaagcaaga aagcaatcaa
     8461 gacagaaaga atggcaaatg taccgttcca agcagcagcc ccgaatcctt tccatgattc
     8521 accaccaaaa attgagttca tcaattcttg gaacccggga atcggtaagt tattgatcat
     8581 tactgctaat gctcctaaga tcattaacgg catactcacc ataaatgagt cccgaatcgc
     8641 aactaaatgc cgttgtgcac caatttttga tgctacaggt ataaaatgtt tctccataaa
     8701 tgcaacaaat ttatccataa atcttccctc ttttctttac tgtagattac gcgttcaatc
     8761 gacgatacag atcaatgatc tcttttgcta aatctgtaaa agctatagat gtcatcagat
     8821 gatcttgact gtggaccgtc aaaagcgtga cttcaacgtg atttccttgt gcttcttgtg
     8881 tcagcatctc tgtttgagag tgatgtgctt ggactaaaga ttcctctgca tctttgattt
     8941 tttcatctgc taaagtgaaa tcaccttttt tcgcagcagc aatcgcttcc attgcatcgc
     9001 tttttgcatt tccgccaaac atgatcagac ccatgatggc ttctagattt ttttgatctt
     9061 ccatttattg tatcctccga taatttttat tatttgttta ttagtttttc tgcttggtcg
     9121 agtacttttt caccattcat catgccatag tcagccatat tgattacatc taaaggaatg
     9181 cctttaggtg ctagcttttc agcaaattga ttttgcataa agcgtacttg cggtcctaaa
     9241 agtaaaacgt ctacattttt agattctagt tgattatccg catctgaagc agatacagca
     9301 aagatgtctg cttccattcc ttttgcttct gctgcctttt gcatttttgt gactaggaga
     9361 cttgtactca ttccagctga acatacaagc atgattgttt tcttttccat tttaaacacg
     9421 ttcctttcta tacttacact tgtatataag caagtagcgt gccaacttta aaagcgcttt
     9481 aaaaagttga tatcatcaca tttaaggtct ataccaagtt gcatacacac taaaaaagaa
     9541 agcgcacact aaacacacaa attaattttt attacctttt ttcttttaac gtgcacaaaa
     9601 aaagttgtga cacaaaactt gtcacaactt ttttcaaata aacggtattc aaaagcttgc
     9661 atctgcggta ataagtccaa ccaagttaaa aacataagat gttgttttta ctttgctatt
     9721 cttattactt gatgcaggac agctttttca caacctctca ataaacggtg ttcaatcagc
     9781 tgaccctggg tattagctca aaacgctgga ttcacaacct cttttatttc aaataaccag
     9841 taaatacaat gaacatctac aaaaaacttc tatttattta tagatttcgt caggcaaatc
     9901 caattctctc ttatcaatca aagtctgata ccacgaagca gattttttca atgttctgct
     9961 tcgttcatcg ttcaattcga ttcgaactaa tccatatcga ttcttaaatg cattcattgg
    10021 tgacacacag tcagtgaatg cccataacat atagccttcg caatttgcgc cttcttctgt
    10081 tgctttgatc aagtaatgca aatgctgtcc gataaattcg atacggtaat catcttgcac
    10141 gattcctttc tcatccatat actgttcttc atattctctt cccataccgt tttctgttat
    10201 cagccaaggg atattatgat aattttcttt tagatacatg gctatatcat acatgatttt
    10261 cggatagatt tcccatcccc tggaattatt cattttcttc ccaggtaaat caaagacttc
    10321 ataatatcgt tcaggatgga aaggtgtctc ttcattccat tgataacgag gggcgcgaac
    10381 gcgtttagga taatattgat tgattccaag gaaatctact gtatgatgct gaatcgtttc
    10441 taaatcctct gttgcaggat cgaaataaat cgattgtttt tgacacaact ccaggaactc
    10501 ttctgtgtag tatcctttta ccatcggatc aaaaaatact cgattataaa acaaatcata
    10561 catataagca gctttttggt cttctggaga attggatcga gcatagacca tttcaggatt
    10621 taaaatacag ccaatccttc caccataatt tccgctgcgg taaatctcta ctgctttagc
    10681 cgttgctaaa actttatgat aattccacat catccacttt tttgtgtttt gttcatgcgg
    10741 ccagcgaaca gcatccaaat agcaacgcgt ttggggaacg attggttcgt tgaatgtaaa
    10801 ccagtttttt accctatcac cgtaacgatc aaaggcaatt tgagcatact tagcataaaa
    10861 atcaactact tttcttgaag accagccatc atatttttcc aaaagaaaag ctgggacttc
    10921 ataatgttcc aaacaaatca tcggttctac gtctgcttcg atcaaagagt cgatcatttc
    10981 acttatatgc tgagcatatt cttcatctac tatacagttc tcataatcag taaaaaaacg
    11041 agcccaattg atagaagtcc gataatgtgt cagatggatg gatttcatca gatccacatc
    11101 ctgctggtat tgttccataa aattagttgc tacggctggg ccatacccat tatgccaaac
    11161 aaaatgttca tttttatacc agctatctat aaacgaatcc tgtccttctt tttttccttt
    11221 ccaaccttcc gtttgccaag cagaagatgc agcaccaaga ataaaatttt ttggaatagt
    11281 aattttcatg atttcctcct gttttttaga tcccatcatt ttccacacga tttgctactt
    11341 ttacaaatgg cagatagatc aaaatagaaa caataataca aacaagttgc gtaataactg
    11401 caccgatatt tcctgctgtt gccagataag cattgacgat cggcggcatt ggccaaggga
    11461 ccattacaac tgctttcgcc gcaaatccta aagcggttgc aaaataacca atcgttccag
    11521 tgataagagg cgttaagata aacggaatag ctaaaattgg attcagcatg atcggcatac
    11581 caaaaataac tggttcattg atgttgaaga tcccaggagc aagggataac ttggtgattt
    11641 gtttcatatc ttcccgtttt ccaactaaca atactgcaat cagtaaaccg atcgtgactc
    11701 cagacccgcc catactcata tacatatccc aaaatggcat agtaataatg ttcggtactt
    11761 cttttccagc ttcaaaagct tccgtattta cagcaattgc cgctaaaagc aacggttccc
    11821 gtatcggctt caccatttga tttccatgga taccaatcac ccaaaagact tgcgcaataa
    11881 acatcaatag caaaataccc ggtaaccctt gtacgacacc ttctaatggg cgttgtacga
    11941 cattgtaaat gatatcataa aggtacattc ctgtaagttc tttgatgata aatcccgcag
    12001 ccgcgatacc cgatacagtc agaatcgtcg ggaataaagc agaaaaacta gcagaaacat
    12061 tcgttggcac ggtatcaggc attctcagct gtagtttctt ctgtttcctc aaccagcaat
    12121 aaagttcaat agaaaggatg gagaccaaca ttcccaaaaa taaccctttc gtatctgtat
    12181 attgtttagc caatacgttt tctactataa cagtctgatt ttcattcact aattcataaa
    12241 cagttggatt aacagataaa taagacatca ctgcgatgat accagggaat acaccatcca
    12301 ctttattcag cttggctaat tcgatcccta tcagaaaaac agcatagatg gtcaagaaac
    12361 ttagtgtgac atagctgatg gcagatgcga taggctttaa ttcttctaaa aaacgcaaga
    12421 aacttatctg tgctaagcca ttttccgagt caaagaccat tgctgaaaac aatgtgccaa
    12481 aagcacccgt aataattacc ggaatcaatg cagcaaatgc gttttttatc accatgatat
    12541 accttaaatt attgattctc gttgccacgt tccctaaaac attggctaat ttatccataa
    12601 aactcattcc agatcccctc attcctgctt cttctccttg acgtcatctc tttttgtcta
    12661 ttagtcagcg cttacatttc gatgaacaga aactatttac tcctcttttt taccaaatat
    12721 aaaacaaaaa ttcatctgat gtatttatca taaaatacat cagatgaact gtcaattagt
    12781 ttctttttct cctattattt tctgtaattc tctccgattt attgccatat ggacagtcat
    12841 tgcatcaaac gcagcaagtg cattccgcct ttcgatggcc tgaacgatct ctgtatgaat
    12901 atcgatcgtc tcgattttca gatgctggat atcataattt ttattaaaca aagcaattga
    12961 ttcattaatg attgggataa tatgcagcaa ggctacgttt ccgctagctt ctgcaatcat
    13021 cgtatgaaaa tcgatgtcta attgaacatg ttcttgtgtg ccttctcgaa aagaagtttc
    13081 aatcttttgc gttaattttt tcatttggac gatttgattc ttcgttgcat attccgctgc
    13141 caaacctgcc atcttaggct ccaataaata tctcagttca aataagtctc gtatcatccg
    13201 atcctgatct tcaatcaaag aaaaaccgag tgggtcattg gcaatccctc gcttatcact
    13261 gacaaatgtc cccgctcctt gccgaacttc aaggatattc ctggaagcta gagcccgcac
    13321 agcttctcgc accgtgcttc gccccacctc taaataatcg gacaattcat attcattcgg
    13381 cagtttatct cctacttgca actgcatttc ctttaaatat ctaaggatct tgtcagtagt
    13441 tacttctact agggttttat tttcttccaa accacatacc tccttttcat ctgatgtatt
    13501 ttttcgtaat tattataaca cgtttgaatc atctgatgat tttttgtata caaaattgat
    13561 taatccgttc atagacatac aaacgaagaa gatatttacc ataaaaaaga ctagga
//
LOCUS       DAMEEU010000076        12926 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.077, whole genome shotgun sequence.
ACCESSION   DAMEEU010000076 DAMEEU010000000
VERSION     DAMEEU010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12926)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12926)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12926
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.077"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(204..1652)
                     /gene="cls"
                     /locus_tag="PB779_002286"
     CDS             complement(204..1652)
                     /gene="cls"
                     /locus_tag="PB779_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDE0739793.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEVAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGEIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYTLQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHTTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLVYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            complement(1804..2697)
                     /locus_tag="PB779_002287"
     CDS             complement(1804..2697)
                     /locus_tag="PB779_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739794.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="PB779_002288"
     CDS             complement(2681..3367)
                     /gene="ftsE"
                     /locus_tag="PB779_002288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HDE0739795.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            complement(3472..4573)
                     /gene="prfB"
                     /locus_tag="PB779_002289"
     CDS             complement(join(3472..4500,4502..4573))
                     /gene="prfB"
                     /locus_tag="PB779_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HDE0739796.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            complement(4699..7233)
                     /gene="secA"
                     /locus_tag="PB779_002290"
     CDS             complement(4699..7233)
                     /gene="secA"
                     /locus_tag="PB779_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HDE0739797.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="PB779_002291"
     CDS             complement(7455..8006)
                     /gene="raiA"
                     /locus_tag="PB779_002291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HDE0739798.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTADAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            complement(8134..8853)
                     /locus_tag="PB779_002292"
     CDS             complement(8134..8853)
                     /locus_tag="PB779_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HDE0739799.1"
                     /translation="MRCSCCGKDIIQNLTFSEIIGVSKSRLPQTCSVCRAQFHLLEAK
                     GCAGCQKPIHLKYEETKKKANTSFVYCNDCQEWKKKYPAYDFQHRAFFTYDEKMQAWI
                     NRYKFMGDIRLAGTFAYKWTQIKKDYPAYIYCPIPLSEKRWLERGFNQVSEMLKAAKI
                     PFQMLLKREQHLLAQAKNTRKERLEMPQPFELAVPLSKIQHKKILIIDDVYTTGQTLF
                     HAADCLQNAQPKIIRTISLAR"
     gene            complement(8850..9926)
                     /locus_tag="PB779_002293"
     CDS             complement(8850..9926)
                     /locus_tag="PB779_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HDE0739800.1"
                     /translation="MFDQPEAKPREVVFFWTGQLTEKQTEIAKRILCHSEKRHHLIWA
                     VTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNELFLRYRYVFPEEKITLLHGNTA
                     TAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYNGDAGLAHAVQTAIRSNGRFIY
                     LSATPDEKLLKEIKQTFELHKLALRFHRRLLPEPVLVFMNNWRQKCGNKKKINSLVRI
                     IQQLIKENRILLFCPSITMMHRLKITLQEAFPEYEITDVSSQDDQRAKKVQKMREAIY
                     EILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQIAGRADRKGPYTNSRVYFFYE
                     EKTSAIRKACQEIKEMNEEGKQML"
     gene            complement(10244..10564)
                     /locus_tag="PB779_002294"
     CDS             complement(10244..10564)
                     /locus_tag="PB779_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739801.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIA
                     LIGE"
     gene            complement(10672..10959)
                     /locus_tag="PB779_002295"
     CDS             complement(10672..10959)
                     /locus_tag="PB779_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739802.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            11086..11730
                     /locus_tag="PB779_002296"
     CDS             11086..11730
                     /locus_tag="PB779_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HDE0739803.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDQAKNFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGVPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSANHFKESIIELLNGQVQFEEGSVSYHEQLITDHI"
     gene            complement(11789..12496)
                     /locus_tag="PB779_002297"
     CDS             complement(11789..12496)
                     /locus_tag="PB779_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739804.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRRDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(12716..12886)
                     /locus_tag="PB779_002298"
     CDS             complement(12716..12886)
                     /locus_tag="PB779_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739805.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVQVKSKRP
                     TNHTKKWMAKNR"
BASE COUNT         3560 a         2801 c         2248 g         4317 t
ORIGIN      
        1 gctatactgg ctttgaaatg tgtctctttt aatagcatat attagcttat ttcttgcttt
       61 ccccaaaaaa caagagatac cccaaagtta atttcgctca tgcgagacgc tttctccatt
      121 tctgacgtac tctcagaaat ggccccgtta aaaaaggaca cgagatctcc atctgttgat
      181 ggttctcatg tcctttttat gttttaaagg agcggcgaaa tcaatcttgc taatccttct
      241 ttcatcttga tgattattcc tcggttttca tacatttctt ttgtgagatg cgtagaaatt
      301 ttcgagtctt caaaaaaagc ttttcttaca cgtgaagcca ttcgttcatc ataaaccagt
      361 gtattgacct caaagtccaa gcgaaatgaa cgaacatcga tatttgctga gccaactgaa
      421 acaatgccac catcgataat catcgtcttt gcatgaataa atccattctc atatgtttcg
      481 atccttgctc catactcgat cagctctgca gcgaaagaat acgttgccca gtaaacgaga
      541 agatgatctg gtttgttagg tatttggata tgaactttta cgcctgaaag aagagccaac
      601 ttcagtgctt catgaatcga tccatccggt atgtaataag gcgtttggat caatatctcc
      661 cgtttggcta acgaaatcat tttcaaataa gtcattttga tttgttcatg ttcggtatct
      721 ggtccgcttg tcacgatttg aacagctata tcaccagtag tgtgaatgga cggaaaaaat
      781 ttgggagaat agcctacttc ttttgtatgc tgagaattcc agtccatcaa aaaacggttt
      841 tgcaaggtat acaccgcttc tccgtaaata cgcaaatgat tgtctcgcca ataaccaaat
      901 ttctttacca atcctagata ttcatttcca acattgaacc cacctgtata tccgatttcc
      961 ccatcaataa ctacgatttt acgatgattg cgataattga tccgaggatt aatatacgga
     1021 acaaatagag gaaagaaaaa tgcgacttct ccgcctgctt ttttcaaatt ctgaaaaaag
     1081 ctggaagaaa cttgtgtgga accccatgca tcaagaagga ctctgacttt tacccctcgt
     1141 cttgccgcct ctgtcaatgc atctcgaact tcttcaccta atgcatcact gcgataaata
     1201 taatactgga agtggatatg gtcttctgcc tgcttgatat cttcaatcag cgcatcgaat
     1261 ttttcacgac catctgtaaa taaagtgatt tcatttttag tcgtatagag cgtactttca
     1321 aataccgtga gcatatagat caattgtttc acatctactt gtccagtagg cggatgagga
     1381 taaagccctc gcatcaatgc ctgtttgtct tcttcaattt ccaggttctt accgattttc
     1441 ccttggatct tcaaatcaaa gattttctct ttggaaatcc ctcttcctaa aaaaatatat
     1501 aaaataaatc ctacaactgg aatgaacatc aaaacgagca gccatgccca tgtttgagca
     1561 gtttcctttc tttctcgaaa aacgatgata aaggaaagca aaatattcat aatcaaaagg
     1621 atcgtaaaaa aattgtcaac gataattttc acggcttcac ctcttcttct accaacttaa
     1681 gaatacccaa gttgtttttt aaagtaaagg gaaaaaagcc gcttccttct attctcctag
     1741 ccaataaaaa aagaaagctg gaacgaaact gtccaacttt ctcattttat ttatattgtg
     1801 gtattagaat ttcaagaaac gtctcataga aatgatcgag ccaagtgaac caatgatcac
     1861 accaatgccg accattaaaa gattgatttt ccaaacgata ttttgtggat gaatcaatga
     1921 ataatgggaa cgtaataatg atggattgat caattggaaa aaccatgcat aaccaaatgt
     1981 gatgatcaaa attggaagaa ttgcaccgat cagaccgatc cagccacctt caaggaaaaa
     2041 cggccagcga atatatccat tttttgcacc gactaaacgc atgatttgaa tttcacgctg
     2101 tctagacaaa atcgtgatcc gaatcgtgtt cgaaatgaga aacatcgcta cgaacagcag
     2161 caatgccgct gcaactaatc cccatgtccg aactgcacca gcgatttgga aaatccgatc
     2221 tgaggaagct ccaccgtaat cagaacgaga aacattcttc aaatctgctg cttcttctgc
     2281 tacttgtttt gtataagaag gatcagtagc acttactaca tacacatcat ataacgggtt
     2341 attgtcacct tcaaacaatt tccaggaatc acccatttcg ttttggattt ttttcaattc
     2401 ctgttctttg cttgaaaatt caactttttt aacatgatct aagtcattca attctttttc
     2461 tagctttttc atctcttcgt cttttgtacc gatatctacg aatacagata catcaacgtt
     2521 tccttctata tcctgagcta atttagttgc attcatgata actgccatga atacaccgac
     2581 taaagtcaac gtgatcgtta ccgcactgac tgaagcaact gtcatccagc cgttacgttt
     2641 caaactcttg atactttcta ataaatggcg gaaaaaggtt ctaatcatcg tatccatatt
     2701 ccccttccgc ttgatctcga ataatgcggc cgttttcgat agcaattact cggtgccgaa
     2761 tcgtatttac gatcgtactg ttatgtgtag ccatcacgac agtagttcct tgggcattga
     2821 tccgatctaa taatttcatg atttcccatg agttttctgg atccagattt cctgtcggtt
     2881 catccgcgat aagtacttta ggcgtattca cgattgcccg agcaatagag acacgttgct
     2941 gttccccacc ggataattcg ctaggaaaga ctcgaacttt gtgtttcaaa ccaacaaggt
     3001 ccagcacttc cattactcgt tttttgatat ctcgaggttt tctgccgata acttgcatag
     3061 cgtacgcaac attttcatat actgtttttc ttggtaataa tttatagtct tggaacacca
     3121 cgccgatttc tctgcgtaga taaggaactt cgcggttttt gattgctatt agatcatgac
     3181 ctgcgacgtt caaagttcct tttgaagctt tttcttctcg atacatcaat ttgatgaatg
     3241 tagatttacc ggctccagac ggaccaacca catagacaaa ctctccttgt tcgatgacaa
     3301 tcgagagatt gcggatagcg gtcgtaccat ttgagtactt cttcattaca tccttcattt
     3361 caatcatggc gttctctcca tatctttttc agtctttagc tattatagca tggcaatgtt
     3421 tcaacatgct tgcaaaatct tacaatttta tttcaattta acaatgggtt cttattgtag
     3481 atgcattttt aaatagccgt caataaataa atcaaggtca ccgtccataa ctgcttggac
     3541 atttcctgtc tctacgtttg tccgatggtc ttttaccata gaatagggat ggaaaacata
     3601 agaacggatc tgtgaacccc agccgatttc tttttgttct cctcgaagtg cagctgcttc
     3661 ttgttctttc ttttccactt ctaattgata aagcttagct tttaacatcc ccatcgcttg
     3721 ctcacggttt ttcaattgtg agcgttgtgc ctgactagct actactgttc ctgtaggcaa
     3781 gtgagtgatc cgtacagcag attctgtttt attgatgtgc tgaccacctg caccacttgc
     3841 tcggtacgta tcgattttca aatcatctgg attgatttct atatcgatcg tttcatcaag
     3901 ctctggcatc acatctaccg aacaaaaaga agtatgacgt cgtttcgctg agtcaaaagg
     3961 cgaaatccgt acaaggcgat gaacaccttt ttctgatttt agataaccaa aagcgttatg
     4021 tcctttaatc agcagggtca cactcttgat ccctgcttca tcacctgctt gataatctag
     4081 tgtttctact tgatagccat gctgctctgc ccaacgtgta tacatacgta aaagcatgct
     4141 gccccagtct tgggactccg ttccgccagc ccctggatgc aattcgacga tcgcattgtt
     4201 tcgatcataa ggtccgtcta acagcataga taattcatac gtcttcattt tttcatctaa
     4261 tgcattgata cgtgtttctg cttcttcttg cattgctgca tcaggttctt cttgcagcat
     4321 ctccaccatc aattcgattt cttctagttc ttcggcaaga gaatggaatt ggtcataggt
     4381 ttctttatta gcgttatttt cgctgatcac tttttgtgcg gcttcgctgt catcccaaaa
     4441 accaggttca gccatttttg cttctgcttc cgcgatgtct tcttccagct gatctaagtc
     4501 aaagagacct cctgaaactt gtgacctttt cctgcatttc tgtcaggaga tttcgaattt
     4561 cggatatttc catgtttttt ccttctttca ctatactttt ttcattatat ctagtctaac
     4621 agaatcagca aataacagaa agaaggtgag acgaattctt aaaaaaagaa tttgtctcac
     4681 caatcctgct gtcagaaatt agtttgcatt ttttccatga cagttcttat attttttccc
     4741 gcttccacaa ggacaaggat catttcttcc gaccttattc acatggattg gctgtttttt
     4801 cgcgctagta ttactatttt ctttggcatc tccgtcttct gagtgagaag ctgttccttg
     4861 agaaacctgt tcacgctgta cgttttgacg gatctcagct ttcataaaga ttcgagtgac
     4921 ttcatactcg atggcgccta ccatatcttc aaacatctta tagccttctg tttgatattc
     4981 gactaatgga ttgttctgtc cataagcacg taagccgatt gactgacgta attgatccat
     5041 tgcatcaata tggtctgtcc atttagagtc cacaacacgc aagatcacga ctttttcaaa
     5101 ttccaacagt tgctctggac catttagttg agccgctttg gtattaaata cttcttgtgc
     5161 tcgttcgttt agatactctt tgatctcctg agctgttttt ccttcgatat ctgcaagagt
     5221 aatgctatct tcatggacaa gagtactgcc ggcaaaatcg atgatacttt ccaaattcca
     5281 attttctttc tctaattgtg tatgcgcatc tactacacga ctgattgtcc gtttgaccat
     5341 gttcattagt ggcttggata agcttttttc ttccatgatt acttcttgtc gctgtttata
     5401 gattacttca cgttgttcac gcatcacatc atcgtattgt aagacgtttt tacgtgtgtc
     5461 atagttattt ccttctacac gtttttgtgc agattctact tgtttcgtca gcatcttgct
     5521 ttggataaca gcatcttcct caccgatctt catccgatct aagaaagctt tgattcgttc
     5581 tgaaccgaat cgtttcatca aatcatcttc caatgacaag tagaactgtg acataccagg
     5641 gtctccttga cgtcctgcac gtcctcgaag ctggttatcg atacgacgag attcatgtcg
     5701 ttctgtcccg ataactgcta gaccaccaag ttctcttacc ccaagtccta acttgatatc
     5761 tgttccccga ccagccatgt tggtagcaat cgtcacagca cctttttgac cagcattcat
     5821 gatgatctct gcttctttaa agtgattttt cgcattcagc acttcatgag gaatacgttc
     5881 ttgattcagc atatctgata ataactcaga tgtttcaacc gcaacagttc cgactaacac
     5941 aggttgacct ttgcggtagc gatctttgat atcttgcacg acagcgtgga acttgctttg
     6001 taatgttggg taaagcaaat ctggacgatc atcacggata accggacgat ttgtcggaat
     6061 ctggtatact tggatgttat aaatttctct gaattcttct tcttctgttt tagctgtacc
     6121 agtcattccc gcaagtttct tgtacatacg gaaatagttc tggaaagtga tcgtcgccat
     6181 ggttttcgtt tcgtcttcga tctctacgcc ttctttagct tcgattgctt ggtgaagtcc
     6241 atctgaataa cggcgtccat ccatgatccg accagtgaac tggtcaacaa tcagtacttt
     6301 tccgtcttgg acaacataat cgatatctaa aagcatgata tagttggctc tcaatgcttg
     6361 atccaagtga tgggtcaatg cagtattttc aatgtcgtat aagttatcca aaccgaatgt
     6421 ttcttctgct ttttcgatcc ctgcttcggt taaactgatt gtttttgatt gtacatcgat
     6481 tttataatct tcttcttctt tcaaacgttt cacgaagttg tctgctcttg tatataaagc
     6541 tgtggatttt tctgcttgcc ctgaaatgat cagcggcgtt ctcgcttcat caatcaagat
     6601 tgagtcaact tcatcgacaa tggcataatt cagcggacgt tgtaccattt gatggcggta
     6661 aacgaccata ttgtctctca agtagtcaaa tcctaattca ttattcgtac tataagtgat
     6721 atcacaatta taagcctcgc gtttttcatc cgaagatttt gagttgatat tcaaccccac
     6781 tgttaatcct aagaaattat aaagttcgcc catttccgtc gagtcacggg ttgctaaata
     6841 ttcattgacg gtaactacgt gtaccccttc gccagtcaga gcatttagat atactggcat
     6901 cgttgcggtc aaggttttac cttcaccagt acgcatttca gggatatttc catcgtgaag
     6961 cacgattcca cccatcaatt gtacgtggta tggatataaa cctaatacac gttttgctgc
     7021 ttctcggacg actgcaaaag cttccggaag taattgatct aatgtttctc ctttttggta
     7081 tctgcccttg aattcagcag tttttgcctg taattgttca tcagttaatg ctgccatttg
     7141 gtcagcgtat gcttcaactt tttttgcaat gctatctaaa cgttttagtt ctttcttatc
     7201 gttttcgata agtgaacgaa tcaaattggc catgcgttgt gtaatctcct tttccttctg
     7261 tgtattatcc agactatgta gactttactt ttcattttat cattagttat agataattga
     7321 aatatcttaa gcgtattaaa gtaagaactt cataatttat tcatatttca tctaaaagag
     7381 gaggaaactc aaaaaaactt gcggcagctg tcagtagctg ctgcaagttt tcgttgttat
     7441 ttaagtaagg ctgatcagtc tgtttcaatc agtccgtatt ttccatcttt acggcggtaa
     7501 acgatacttg taccatttgt ttctgcatct tcaaaaataa agaagttatg tcccagcatg
     7561 ttcatttgta agactgcttc ttcactatcc attggtttca atgaaaggcg tttcgtacgt
     7621 acgatatcta attcagaatc attttcgttt tcgtcctctt cattgaataa agcagcagca
     7681 tctgcagtat tcatgcccgt ttcacgggat ttacgattaa tttttgtttt gaatttgcgg
     7741 atttggcgtt ccaatttgtc aacaaccaaa tcgatacttg cgtataaatc tggagaagtt
     7801 tcttcggcac gtaatacaag ataaggtaat gggatcgtta cttccacttt tgctgttttt
     7861 tctgtataaa cttttaagtt cacatgcgcc gttgcatcgg gtgcgtcact gaaatagcgt
     7921 tctagtttgc ctactttttt ctcaacgtag tcgcgaatcg cttcagttac ttcgatattt
     7981 tcgccgcgta cattatatct aaacataaaa attacccctt tcgtctacca caatcaagaa
     8041 ggagaaggac cactctttcc ctcttcttaa ttctattata tcgaactcta ggttatttgc
     8101 aaattaaatc gctatcaaat ttccacatct gattcatctt gccaaagaaa tggttcggat
     8161 gattttcggc tgtgcgttct gcaagcaatc tgctgcatga aaaagcgtct gtcctgttgt
     8221 atagacatcg tcaataatca atattttttt atgttgtatc ttagaaagag gtacggcaag
     8281 ctcaaaaggc tgaggcatct ccaatctttc ctttcgcgtg ttttttgctt gagcaagcag
     8341 atgttgctct cttttgagca gcatctgaaa aggaattttt gctgctttca acatctcgct
     8401 tacttgattg aatcctcttt ctagccacct tttttcagat aaaggtattg gacaataaat
     8461 atatgccggg taatcttttt ttatctgagt ccatttatat gcaaaagtcc ctgctaatcg
     8521 gatatctccc ataaacttgt accgattgat ccaagcctgc atcttttcat cgtacgtaaa
     8581 aaaggcgcgg tgttgaaaat catatgcagg atatttcttc ttccattctt gacagtcgtt
     8641 gcagtaaacg aaactagtat ttgctttctt tttcgtctcc tcgtatttca aatggattgg
     8701 tttttgacaa cctgcacaac cttttgcttc taataaatgg aattgtgcgc ggcaaactga
     8761 acatgtctga ggaagtctag atttcgacac tccgatgatc tcgctgaatg ttaaattttg
     8821 aatgatgtct ttaccgcagc aactacatct cacagcatct gcttcccttc ttcgttcatt
     8881 tctttgattt cctgacaggc ttttcgaata gctgaagttt tttcttcata gaaaaaatag
     8941 actcgactgt tcgtataagg acctttacga tcagctcttc ctgcgatttg caccaaagag
     9001 gatttagtaa aaactggatg atctgctcct aaaacgatga cagagattct ttcaaatgtg
     9061 actcctcttt ctaggatcat tgtggttaac agtatctcgt atattgcttc tcgcattttc
     9121 tgaactttct ttgcccgttg atcgtcttgt gaagaaacat ctgttatctc atattctgga
     9181 aaagcttctt gcagtgtgat ttttaaacga tgcatcatcg taatacttgg acaaaataaa
     9241 aggatacggt tttctttgat tagttgctga atgatccgca ccaaagagtt gattttcttt
     9301 ttgtttccac atttttgtcg ccaattattc atgaaaacaa gcacgggttc aggaagcaag
     9361 cgccgatgaa agcgcaaggc aagtttgtgg agctcaaatg tctgcttgat ttcctttagt
     9421 aacttctcat caggcgtggc acttaagtag atgaatcggc cgtttgatct gattgctgtt
     9481 tgcacagcgt gagctagccc agcatccccg ttataaggaa acgcatcgat ctcatcgatc
     9541 actattaaat caaaggaccg ataaaaacgg tatagctgat gaatcgtaca gataacaaaa
     9601 gaagtaaagg tataagccgt tgctgtattc ccatggagca acgtgatttt ttcttctgga
     9661 aaaacataac gatagcgtaa aaacaattca ttacaaacat cgactcgcgg tgtacaaatc
     9721 gctactcttc ctccagcttt taaagtttcc actaaaatag gataaagcat ctctgttttc
     9781 cctgcacctg ttacagccca aataagatga tgtctttttt ctgaatggca aagtattctc
     9841 tttgcgattt ccgtttgttt ttcagtaagc tgtcctgtcc aaaaaaagac gacttctcga
     9901 ggttttgctt caggctgatc aaacaaatat aaatcttgtt gagtgtcgca tcaccctaaa
     9961 tatagacaat gtgtacaaaa ataaccgtaa tctgcaagct gtccaacaat gacggacgtc
    10021 ctcattccac agcgatgaca aagaatccag ttgcccaaac gttccactgc tgcgatcttc
    10081 tcataatttg gtaaatttac ctcctcacag tctattgctt taatatctct cgtcagaagc
    10141 cttctacccc aaaaatgatt catattattc gccctaaaaa aatatacgaa aaaacaagcg
    10201 atctattttt tggatcgctt gttcgatagt tatactgttc tatttattca cctatgagcg
    10261 cgattgcttg atctaacact ttttcgccat tcatcatacc ataatcagcc atattgatga
    10321 catctaaagg aatgcctttt ggttccagac gtttctcaaa atcagctttc ataaagcgaa
    10381 cttgtgggcc taataacaac acatccacgt ctttatttgc aagattgtta tctgcgtcag
    10441 aagcggacac agcgaaaata tcagagtcga ttccttttgc ttcagcagct ttttgcattt
    10501 ttgttactag taaacttgtg ctcataccag ccgaacatac aagcatgatt gtttttttag
    10561 ccatattttt ctctcctttt taaaacaaac tacgcaaacg ttttcttcgc gtctgttact
    10621 ttattatata aaaagaaaga aatttgtcaa cgttttctaa acgcggttta tttaatcaaa
    10681 tagccaacta gatttcacta atttattgaa cacgacatat tctttgtcca aattgatgac
    10741 aactacttca tagcctgcat ttatccagcc ataggcacct ttttcagggt gtttataatc
    10801 atttgcccac caatctgtac tttcccttgc tgttttggga agtccgttac tgggaaacag
    10861 cagttcgtca aattgggtaa aggtcaacgt tacttgagag ccgccattgt tcttcaaata
    10921 atgcgtaatt gcatcgtact ttttcattcg ttcctgcatc cccagatcca cctgcctttg
    10981 tctttattat cgcatactac agcaattgcg caaccgttac agtgttgaaa caacctagaa
    11041 ctttatttat actgaataaa gaaaatgaaa aaaagaggtg acaagatgat cgagcgctat
    11101 cgtacaataa aagaaaatgg acaaagtgag attgagatca aaaaatcacg ctttatctgt
    11161 tctcttagac gaatagaatc agaggaccaa gcaaaaaatt tcattcaaga aataaaaaaa
    11221 gaacattgga aagcgaacca taactgcagc gccttcatca ttggagaaaa aaatgaaatc
    11281 cagcgaagca gcgatgatgg agaaccaagt ggaacggcgg gcgtaccgat gttggaagtc
    11341 ctcaaaaaaa atcaactgat caatgtagct gcagtagtca ctcgatattt tggaggaacg
    11401 aaactcggca caggcggatt aatacgagca tacactcatg cggtctctca agcattgtct
    11461 gacattggaa tcgtagaagg taccttgcaa caggagatct ctgtgatgat cacgtatccg
    11521 caactaggaa aattacagaa ttatcttgaa ctccaacatt tttttataaa agaaatccaa
    11581 tatactgatc aagttagcgt catctgtgct gtagatgaaa aaagtgctaa ccactttaaa
    11641 gaatccatca ttgagctgct gaacggacaa gtccaatttg aagagggttc tgtttcttat
    11701 cacgagcaac tgataactga tcatatataa aaacaggtga ttctgattct cttttatttc
    11761 taataaggaa tcagggatca cctgtttttt atttttccaa ataaaactca aaacgatttc
    11821 ctacgtattg cgtacgcaca tactcaaacg gcgtaccgtc ttcaaaataa gaaatctggc
    11881 gcaaacgaag aactgcatct cttcgtttta cctctaaata gtcagcaatt ttctcagaag
    11941 ccaacacagc agtaatcgtt tgattcgctg gaccgatctt tttcccgcct ttttcttcta
    12001 gcgtgcgata caacgattca gtaatctctg ctttgctgta gccatcgatc agcttttgtg
    12061 gaacactggc aacttcaaaa caaataggga catcatctgc gaaacgaata cgttccattc
    12121 gcaagatcgt gtcatcttta ctcaagttta gtttttccat ttcacttgag cttggcgaag
    12181 tcaagaaata agagattgtc cgactagacg gtactcgatt ttgtgattcc ataatttctg
    12241 taaaacttgt tgcaccagac attttttctt gtactttttc tcgcgcaaca tacgtacccg
    12301 aaccgatctt tctttctaag attccttcat ctgccaagtt ttgaattgct tgtctcaacg
    12361 tcatacggct gacattgaat ttcactgcta attctctttc tgaaggaaga cggtctccga
    12421 ctttccatat accttgttcg atttcatttt ttaattggtc atgaatctgt atatatacag
    12481 gtaattgatt cgacataacg tacacccgtc ctttcgtttc ttctattata actggtatat
    12541 acctgattca caactgaaaa agataaaggt ttctatccat caacagagga tttagacaca
    12601 catcgttctc cctactccta ttgtcagaaa caatttttta gatatgttca acctagaaaa
    12661 taacaaaaga ccctaaaatc gatgaaaatg ccgacttatg gatcttttgt tattattagc
    12721 ggtttttagc catccatttt tttgtatgat tcgttgggcg ttttgatttt acctggaccg
    12781 cttttccgcc ttttttcgga atattcactt caatattgta tttttctgat ttgaccaaat
    12841 catataactt ttcagctgct tcgtctactt tttctttcca tttcatgtgg atccctccaa
    12901 ttcttgtagt taacttaact ctatct
//
LOCUS       DAMEEU010000077        12915 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.078, whole genome shotgun sequence.
ACCESSION   DAMEEU010000077 DAMEEU010000000
VERSION     DAMEEU010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12915)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12915)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12915
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.078"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(28..963)
                     /gene="murB"
                     /locus_tag="PB779_002299"
     CDS             complement(28..963)
                     /gene="murB"
                     /locus_tag="PB779_002299"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HDE0739806.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(1036..1956)
                     /locus_tag="PB779_002300"
     CDS             complement(1036..1956)
                     /locus_tag="PB779_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0739807.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            2069..2821
                     /gene="xth"
                     /locus_tag="PB779_002301"
     CDS             2069..2821
                     /gene="xth"
                     /locus_tag="PB779_002301"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HDE0739808.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            3685..4218
                     /locus_tag="PB779_002302"
     CDS             3685..4218
                     /locus_tag="PB779_002302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HDE0739809.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
     gene            complement(4708..5232)
                     /locus_tag="PB779_002303"
     CDS             complement(4708..5232)
                     /locus_tag="PB779_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739810.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(5225..5698)
                     /gene="tsaE"
                     /locus_tag="PB779_002304"
     CDS             complement(5225..5698)
                     /gene="tsaE"
                     /locus_tag="PB779_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HDE0739811.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(5821..6801)
                     /gene="pta"
                     /locus_tag="PB779_002305"
     CDS             complement(5821..6801)
                     /gene="pta"
                     /locus_tag="PB779_002305"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HDE0739812.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(6954..7634)
                     /locus_tag="PB779_002306"
     CDS             complement(6954..7634)
                     /locus_tag="PB779_002306"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HDE0739813.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            7760..8629
                     /locus_tag="PB779_002307"
     CDS             7760..8629
                     /locus_tag="PB779_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0739814.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            8655..9170
                     /locus_tag="PB779_002308"
     CDS             8655..9170
                     /locus_tag="PB779_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739815.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(9217..9810)
                     /locus_tag="PB779_002309"
     CDS             complement(9217..9810)
                     /locus_tag="PB779_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739816.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(9835..10014)
                     /locus_tag="PB779_002310"
     CDS             complement(9835..10014)
                     /locus_tag="PB779_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739817.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(10091..10600)
                     /locus_tag="PB779_002311"
     CDS             complement(10091..10600)
                     /locus_tag="PB779_002311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739818.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(10696..11076)
                     /locus_tag="PB779_002312"
     CDS             complement(10696..11076)
                     /locus_tag="PB779_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HDE0739819.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEIFGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            11406..12155
                     /locus_tag="PB779_002313"
     CDS             11406..12155
                     /locus_tag="PB779_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HDE0739820.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(12476..>12915)
                     /locus_tag="PB779_002314"
     CDS             complement(12476..>12915)
                     /locus_tag="PB779_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDE0739821.1"
                     /translation="KKAEGSPCFLLYQTFPGIGALTAALLLGELGDITRFKTHKQLNA
                     FVGIDIRRYHSGKYTGQDRINKRGNPKARKIIFFTIRNMIRQQRAAPNHIVDYYYKLK
                     KQPIPKKDKVATVACMNKLLKCMHAMVRAHTEYDYAYAVSVDH"
BASE COUNT         3733 a         2612 c         2321 g         4249 t
ORIGIN      
        1 tttacttatt ttaagttcca ttacttatta attggctaaa cttctgcttg tttctgatat
       61 tgcttgtttt tctccaatga tccgcacttc tgtttctaaa gacacatcaa atttttcttt
      121 gattacttct tggatgtgcg caatcaattc aatataatct gtcgctgtcg catgatcgat
      181 attgacgatg aatccagcat gtttttcaga gacttgtgca ccgccccatt tcaggccttg
      241 caatcctgct tgttggatca gctgacctgt atagtgtcct actgggcgct taaagacact
      301 tccgcatgaa gggtattcta atggctgttt tgattgacgc aattcggtca actcatccat
      361 tcttgctttg attgcttcat aatcccctgt ttgcaaactg aatcgagctt ccaatacgat
      421 agcacgtaat tcttggactt tactgtgacg ataagaaaat accatttcgt cttttgtcaa
      481 agttttcaat gttccatctt caagcaaaag atccacttca gcaaaaacat ctttgatctc
      541 tccgccatac gcacctgcat tcatataaac cgctccaccg acacttcccg ggatgccgca
      601 agcaaattca aatccagtca atgattctgc caaagctgca taagtcgtat caatcagtga
      661 ggcacctgct tccgcaatga ccatcgttcc tttgacatga atctgtttca tttcagtcag
      721 catgatgact acaccgcgaa tcccgccatc ttgaacgatc agattgcttg catttcctaa
      781 taccatccaa ggtatatcat ggattcggca ataatcgatg atttgcttta cttcttcttg
      841 ttttttcggg aatgcaagga catcagctgg tccacctgtt ttcgtaaacg tatagttcat
      901 caatggttca tcaaacaata tagtaatcgt ggctaagctt tcaactattt cttctttatt
      961 cactgaggat tttcctttct tttctcaaac gtcctcatta ttctatcacg cttaatacaa
     1021 tcttgccagt cttgttcaaa gttgatgacg gtagtgatct ttaagcactt cctcacataa
     1081 ttcatgactt cttacaactt ctttttgttt aagcaattct gtttccgatt tacctaaacg
     1141 gatctgagaa aagaaggcct ctaccattgg ctcaaacccg cgtttgacta gcgtgtttgt
     1201 ccagtcgcca aattctttca ctttttttcc atcagcatct tgaatgacaa gctgggtcag
     1261 atcgtttact tcataagtac catttttact tgttacttga tatttttcta tattagcgcc
     1321 acttgctaaa tccatcgtta aaatagccgt ttgattttgt gtttctaatt gtaaaatggc
     1381 atattccaaa aattcctttg tttctcttat ctggtatttt gttctcaaaa tgggttcatc
     1441 taataaatac acagctgtat caataagatg taaaaacaaa tcataaagga cgaactctgt
     1501 cgtttctttt gccgctattc gatttttttg caggtggatc aaccgcttat ctgggatacg
     1561 tttcaattct tctaccatag gagcaaagcg ccggttgaaa ccgatcatca aaattatttg
     1621 gttcttatca gctaattctt gcaattcacg aacttcattt agatggacac tcagtggttt
     1681 gtcaatataa acatggatac cattttctag acattttttg gctaattcat aatgtacttt
     1741 tgttgctgcg tggatcatac atgcttcgat tttttcttct aaaagctcat cgatcgtttc
     1801 atatagatgt tggaacccgt actctttttg aattctttct tttgtttctt tatttcttgt
     1861 tgcaaaataa aaatcaagtg ttccttgttt tttcgcataa gttggtaaat atgctttttc
     1921 tgcgatattc cctacaccga ttacaccaat cttcatctac tttcctcctg gatcatttag
     1981 ttactttcat cttacaccat tttttactaa aatgaggtac aatagtatcg caaaggtaag
     2041 gaaattaatt cgaaggagtg tgcttttatt gaaatttatc tcttggaacg taaacgggct
     2101 tcgtgccatc gtaaataaaa attttttaga agtttttcat gagttagacg ccgatttttt
     2161 ctgtctgcag gaaacgaaac tccaagcagg acaaattgat ttagatcttc caggttatta
     2221 tcaatattgg aattacgcgg aacgaaaagg ctattccggc acagcgattt ttgctaaaaa
     2281 accagcattg aatgccactt acggaatggg tatcgatatc catgatacag aaggccgtct
     2341 gattactttg gaatattccg atttctttct tgtaacctgt tacacgccaa attctcaaag
     2401 cgaattaaaa cgtttagatt accgattaga atgggaagaa gccttttata attatttgga
     2461 aaatctaaaa aaacaaaaac cagtcatcgt gtgtggggat ctaaatgtcg ctcatcaaaa
     2521 gattgatttg aaaaactgga aaacgaatca aaaaaatgct ggattcactc cagaagaaag
     2581 agcggctctt tctcgactgt tggataacgg gtttatcgat acattccgtt atttttatcc
     2641 aacccaggaa ggtgtctact cttggtggaa ctaccgattc aattcaagga aaaacaatgc
     2701 tggttggcgg atcgattact ttttgacgag caaagattta gagccaggac tagctgatgc
     2761 aaagatccat acggacatta tgggcagtga tcattgtcca gtagaattag atttgaaata
     2821 aagaggttgt gaaaaagtcg tttagtttcg agtattaaga aaaattttgt gaaaatggct
     2881 ttccacattt tgcataaatt tggcataata ccgagaaact ggcttttgaa cactgtttat
     2941 cgagagattg tgaaaaagct gtcctgcatc aagtaataag aacagccaaa caaaaatagt
     3001 tcctcatatt tttcgtttgg ttgggcttat taccgcagat acaagctttt gaacaccgtt
     3061 tattaagagg ttgtgaaaaa gctgcactgc atcaagtaat aagaacagcc aaacaaaaat
     3121 agttcctcat atttttcgtt tggttgggct tattaccgca gatgcaagct tttgaacacc
     3181 gtttattaag aggttgtgaa aaagctgcac tgcatcaagt aataagaaca gccaaacaaa
     3241 aatagttcct catatttttc gtttggttgg acttattacc gcagatgcaa gcttttgaac
     3301 accgtttatt gagaagttgt gaaatcagcg tcctgacctg agtattagag aaacaaatgg
     3361 caaaatagtt cctcatattt tgctattttt tgagctaata ccgagggtca gctgattgaa
     3421 caccgtttag tggagaagtt gtgaaaaagt cgcctacttt cgagtcgtaa gaaatttttt
     3481 tgaaaatggt tcctcacaac tttgcataaa tttgacttaa taccgagaag tcatgatccc
     3541 catctaactc caaatcacaa ggaatgagtt caaaaactag cttttctcaa caaatattac
     3601 ataaaaaatt ctatgttttt tgttaaattt atttgctttt ttcaaaagta tgttacagta
     3661 atttcccaag gaggttttac agaaatgaat tttgttgcca tggattttga aactgccaat
     3721 catcagcctt atagtgcttg ttctcttgcg ctagtcatgg taaaaaatag ccagatcgtt
     3781 gatgaattct atacattgat acagcctgag actccttttt tctggcgaaa tgtccaaatt
     3841 cacggaatcc atcaagaaga cgtacgcaat gcgccgaaat tcccagaagt ctggcaaact
     3901 atccaaccat attttcaaaa aaatcgttta gtcgttgcac ataatgctgc ttttgataca
     3961 aaggtcttag cgggatgctt agattattat catcttgaac agcctaatta tctttcttta
     4021 tgtacagtga aaagtagccg tcgcctgttt cctgaatttc caaatcatcg attgaacact
     4081 gtgtgcgaaa atttgaacat ccaattagat catcaccatg atgcattgga agatagtcgt
     4141 gcatgtgcgg aaatcctgct ttatcaagaa aaaaaattcg ggacagatcc attgaaaaaa
     4201 cttgtgacta taaagtaaaa gaatacttat gaaacacaca aagaggtcgt gagcctgccg
     4261 tttcactccg agtcacaagg agcaatttca aaaaatagct tctcatgttt attaaatatt
     4321 gtgactggtg accgaggagc tggcaggaga acaccgttta ttggagaggt tgtgaaaaag
     4381 ctgttctgca tcaagtaata agaacagcca aacaaaaata gcttctcata tttttcattt
     4441 ggttggactt attaccgcag atgcaagctt ttggacaccg tttaccaaga ggttgtgaaa
     4501 tcagcgtttt gacctgagta ttagagaaac aaacggcaaa atagttcctc atattttgcc
     4561 gttttttgag ctaataccga aggtcagctg attgaacacc gtttattcaa aaaaaatgga
     4621 ctgcgacacg acttttgtca cagtcccttc gtgtgttttt ctgccttctc aaaaggatga
     4681 cagtttctca ctcttttcct atttcttcta ttcaatcaaa taactcattt tatatacatc
     4741 taaaaattca cctagatctg ttcttgcccc tctaggcatg accgcttcga tttggaagcc
     4801 catttttcgg taaaggtgta cggctctttc attacgaact tgaacgtcaa gctccaatcg
     4861 aaaaagtaca cccatttcct tcgcccaact gatgatttct tctagcataa gagtgcctag
     4921 tcccattccc caatattcct gcagaatact gataccgact tctcccacgt gagacaaacg
     4981 aaattgactg tctgccttga cagatgctgt tccaataatc gtcccttcat agattgcaag
     5041 cagcaataaa ttattattgc tttcgtatat ataatccaac tcttcttcta aggtttctgg
     5101 tggtaacagg agttctgctt catccaaaac taaaaattct gtctccttat taacttgtcc
     5161 catcatcaaa agaatgtctt ttgcatctcc tggcactgct tcccgcaaga tgatcccaac
     5221 ttcttcactc atgattttca gcccattttt ctagaattcg ctgtttgaag gtttcacttt
     5281 gctccccgta tgagattagt ttcacatacc gcttttctaa atctgtatca cttttttcta
     5341 aaatcagttc caaataatcc tccggcagtg cttcttctaa tagatttccc cattcaacaa
     5401 cggaaagccc atcaccttca aaatattcat ctaaccctaa atctgctccg ctagctgcta
     5461 cccgataaat atccatatga tacaacggaa tccgaccttg actatattct ctaataatcg
     5521 tgtatgtcgg acttttgatc atttgcgtta tccctaatcc ttgggcaatt cctttcgtca
     5581 acgttgtttt acccgcacct agatcaccag tcaatatcag attgtcacct ggcattgcgg
     5641 aatgaccaat tgcctctgcg aattgttctg tcattgttaa tcctgatagt tcgatcattt
     5701 ttcatcttct cccgctcttc tttctttttg ccagtatatc gcgtaatgaa gtttttttaa
     5761 agaaaaaatg aactagtcaa gaacagcagc tgctgttttt ggctagttcg cgtgtatttg
     5821 ttaatcaatc aatgtttgtg ctgctgtgat aatcgataat ttatatacat cttcttcatt
     5881 tgctccacga gacaaatcag aaaccggttt gttcaagcct tgtagaattg gtccgattgc
     5941 ttcaaagtta ccgaaacgct gagcaatttt atagccgata tttcctgact gcaattctgg
     6001 aaatacaaag actgttgctt gaccagctac ttctgaatct ggcgctttca gttgtgcaac
     6061 tgaaggaaca taagaagcat caaattgcaa ttcgccgtcg atcatgtatt gtggcgctag
     6121 ttttttagcg attttagttg cttcaactac tttgtctact tctggcgatt tcgctgagcc
     6181 ttttgtcgag aagctcatca ttgctacttt tggttcgata tcgaacaatt ctgctgtttt
     6241 tgcagaatct acggcgattt cagccaattc ttgcgcagtt ggattcacgt tgatcgcaca
     6301 atccgaaaag acatattttt cttgatctct tccacgtacc atgatcatcg ctccgcttgt
     6361 ccgactgatg ccaggctttg ttttgatgat ctgaagtgct gggcgaacag tgtcgccagt
     6421 cgaatggatc gctccagaga ccattccgtc tgcaatcccc atatacgtaa gcatcgtacc
     6481 aaagtaattc acatctttta aaatcttttc tgcttgttct ttggatgcct ttccatttct
     6541 acgttcaaca aaagtatcca ccatttcatc ccacttatcg taattatcag ggctgatgat
     6601 cgtaaagcta gatgttttga ttcctctggc atgcgctgca tttcttattt cttcttcgtt
     6661 ccctactaaa atgggttcca caagttcttc tgctttcaac cgggcagctg cgcctaaaat
     6721 acgagcatca gtagcttccg ggaaaacgat tttgatccca cggcgaacaa ttttaaatct
     6781 taaactatca aacaattcca caagatgacc tccagacgtt tttatatgta ttatcataca
     6841 ctattccaga aaaaaagaac agtttatttt atctgtatca gtcaaaaatg ctggaaaaat
     6901 taagtttttc acatacaaag cgaactgcac tataacagga aagcgctgtt ttattacact
     6961 gtttcaggca gttgccaatc aatcggttct tctcctaacg caaggagcgc atcattcgtt
     7021 ttcgagaagg gtttggaacc aaaaaagcca cgacttgcag ataacggact gggatgtgga
     7081 gatgttatga tgatatggcg actcttatcg atcattttga ttttttcttg tgccggtttt
     7141 ccccacaaga taaacacgat tggtttttcc cgttcattta atttttcaat gatcgtgtct
     7201 gttaatcttt cccaaccttt cccgcgatga gaatacgctt gcccttcccg aacggtaaga
     7261 acggtgttga gtaaaaggac tccctgttta gcccatgaca ctagatttcc atgttgaaca
     7321 ggtgcgattc caagatcatc ataaagctct ttatagatat ttcttaacga tggcgggatc
     7381 tttacgccag gttgcacaga aaaagataag ccatgagctt gattttctcc atgataagga
     7441 tcttgtccta aaatcaccac tttaacttct tcataaggag tcaattccaa tgcttcatag
     7501 atatgataca tatctggatg gatcttttgg gacgcatatt ctttttttaa aaattctctt
     7561 agatgcagat aataatcttt tgaaaattct gaggacaaaa cttcttgcca actgttatga
     7621 atgatttctt tcaaaaactc cacctcctaa taaaaagaat aactcacatt ttcttcaatc
     7681 acaagggaca atcttcaccc tcagcacttg attaatatgg taaactagga acaagaagca
     7741 gaaaggaacg ataatcatta tgatcaaatt aattgcatca gatatggacg gcacattatt
     7801 agatgcccat atgagtgttt ctcctgaaaa tgccgaggcg atacgttttg caaatgatgc
     7861 cggtgttgag ttcatggtcg ctactggtcg aaactatcaa gaagctcgcg cagctttaga
     7921 tgaggtagga atcgattgtg cgatgatcac tttgaacggg gcacaggtat ttgataaaga
     7981 aggaaattca ttgtttaccg tgtcgattcc aaataatcaa gcaatctctg ttttagatat
     8041 tctagatgct aacggtattt actatgaagt agcaaccaac gatggtcttt attctgaaaa
     8101 tcaagcgaaa cgaattgaaa gttttgcttc catggtggct acccatttac ctcaccttac
     8161 gtataaaatg gcgattgcca tggcctcagc taagctggag ttattgcaca tcacatacgt
     8221 ggacagtatt cgtgctattt tggaagaaaa gaatctggaa gttttaaaaa ttatttgttt
     8281 tcatacagaa gggccagctg tattaggtcc agttggaaag cagatttctc ttttaggcga
     8341 tctagccgtt acttcctctg gtcaaaacaa tatcgaagtg aaccataaaa acgctcaaaa
     8401 aggaattgct gttgcccatg tcgctcacga gcgtgggatt tctttagaag aagtcatgac
     8461 gattggcgat aacttcaatg atgtcagcat gctgcaagta gcaggagtca gtttcgcaat
     8521 gggaaatgca gaaatcgaag taaaagatta tgccaaatat acaacggaca caaaccttga
     8581 atctggcgta ggaaaagcca tattgcgcgc gattgcagaa gacttgtagt tttatctaga
     8641 aaagagggat atagatgtca gaatttttca ttcaggaaaa gcagcttgga cgtgcaactc
     8701 ggacaattgt caaaaacgaa aaaggacatt ccctgttttt gatggttggt cgctggggaa
     8761 caaagggcga tgcattgtct ctttatgcca tgaatggcga tctcgttgct cacatcaagc
     8821 agataagcct gacattcggt acgcgttttg agctgtataa agagttcgaa aaggtgggaa
     8881 ccatgcagaa aatattcaat tggcccggtg acttttatta tattcgtaga cttcactgga
     8941 cagtccaagg tgatatctat aatcatcaat atcaaatcca tcatttcaat cagcaaatca
     9001 tgaaaatgga taaagcaaca cttttttcag gagattacta tgtattggat gtctcaaatg
     9061 atgaagatgc tccagtttgt atttgtattg ctgcggtttt agattactgg ctctaccgta
     9121 aagacaaaag tcgcgataag cctgtttctt accgacttaa cttaagttaa aaagatgtac
     9181 ctgaaatgcg gaaatacgca tttcaggtac atctttttag atattctttt gcatatgatc
     9241 ataaagatga ccactgatca tccgctgacc gacaactttg aagtcatggc gttcgtataa
     9301 ttttttagcc tttggatttt tttcatccac acttagaccg atgacggagc gattagcttt
     9361 cttcgccaat ttaggtaatg cttctaataa tcgcgaaccg atgccttgtc ctctaaaatc
     9421 ttctgataca ctgatagagt ccaaatacca ttcgttggga aacgtttctt tatcaatgaa
     9481 caaacgtgta gacgcatcta gctgatattt ctctaagata ggtaccagtg gctgatcgat
     9541 gattgattct tcttcatctg tataaccgta agcaactcct gcaactttac cgtctatttc
     9601 ttctacgata cctcgtgaat aactgtaacg ataatttgga tcagtgattg cttcttctaa
     9661 aatctctaaa gtcttttgtt cccctgtctg cttcaaaaat ggcagttcca tatcttttag
     9721 aatcactaag atcaatgggg cgatttctgg agcatcttct tttctcgcaa aacgaatcat
     9781 agtttcctct ccttttctcc attctaacat gcagaaaaag aaatcgcaaa atcgttattt
     9841 taaaaaatct tcaatctttt cagtaatgaa ataaccatga gtaacgattc ttgccgcttc
     9901 agttcggcaa taagggcaga cgactggcat ttctttatca ttatgttcga ctacattatt
     9961 gacttcttcg tatgcaaatt tttttccgca attagggcat ttcatttttt ccatgttatc
    10021 tcaacttcct ttcatcttta ctctcttagc ttactcttat attgtaaaaa agagaagcaa
    10081 tatccttctt ctatgcagat atccatacct gacggtcctg ttctccatct attaatcgga
    10141 ctttataata aggacgttca tctttgacta gaagtgtcca ctctttcact tttgcttttt
    10201 tcccgtagta gctgactgct tccttcatcg ctgcttgcgg ttgtttgaac tcttccgttt
    10261 tttctatatc aaaaagatgt tctgcggcct tttccgtgtc atttcgtacg gttgttttcc
    10321 cagtggatgg attgactgct atgacttgtc cttcacaaaa aaactggtat tcatatgttg
    10381 cattcgtagg attctccaaa tctttttcaa ctgcaaaatg aatagcagat atgttatgtt
    10441 cttttgtttc gttttttacg attgctgctg cttttttcaa tgagatccga tattcctggt
    10501 cactaatatc atccatgtga aaagcggcat tgagcagtcc cgtcataccg gtaatcccta
    10561 ttacgatgag ggcagcaaca ccaaacatca tttttttcat tcttcattct cctgtttctt
    10621 ttttttaaag aatatcaaga aatgaacgaa tgaaaaatcg aatgaaacga aaaaaaagtg
    10681 acaattttgt tatctttatt cgtgcagttc taatggcaat ccgtctggat caaagaaaaa
    10741 cgtcattttt tttcctgtaa aggtatcttc tctaatcggt tctgattcga tccctaagga
    10801 ctgcaattct gcaattgttt cttcaatatc gtctactttg aaagcaagat gacgcaagcc
    10861 acaagcttct ggatagtttg gtcgttgtgg cgcattagca attccaaaaa tctccaattc
    10921 agcacttcct agtttcagat ctaatttata gtcatctcgt tctttgcggt aattttctct
    10981 gattacttca aatcctaatt tattaacata aaaatcacgt gatttctgat aatctgaaac
    11041 aatgatggct atatgatgga tcgttgtaag gttcatatga gcactcctat tcttcgttta
    11101 agctcggatc tatattaatc tccagttcca ttgtaaatgt gtcagattga aaaaaatagc
    11161 tgtttttcct ttttataaga aaaaaggcaa aaaaaacaga aagtaggtcc tccaagacac
    11221 tcttcctgtt cccaatataa taaatgaaag taagaaatta tattttcaag aaaacaaaca
    11281 gaaaattatc ataacacaaa ttatttataa ttgaaagact agtttttttt caagaaaagc
    11341 atacaataga ttgtgttagt aaatacagaa cacactacat ttagtgtctt aaggagtcct
    11401 catacatgaa gtcatatttt cagtttttag ctcatcagct aaaaggctgg ccgcaacaaa
    11461 attattatct tttctttttc agtcttggct gccaggtcat gactcttgtc aatagtccca
    11521 tcacttggct gtccgttatt acatttatcg gtaccacgct tggtgtattg tgtattttat
    11581 ccatcaatgc ggcaaaatca gtcaacggta ttttaggtat tttgtctgcg atttgtttta
    11641 ttatcgttgg gttttcagca aagaactatt taagtatcgg tgaacagatt gcttatatga
    11701 tcacattgga tatccccgta ttgttaagta aagaatggaa tcataatatg gcttcaaaaa
    11761 tccgaaaatt cactggaaaa agctggttta tcgcaatcat cagtactttc cttgtctatc
    11821 ttgtttcagg attcctgatt ggtcgttata cagatgatcc tcggccgtgg gtagatgcca
    11881 ttgctttttc tattagcttg actgctggta tcatcagttt cttgcgttac aacaaccaat
    11941 attactggtg gttagcttca gggcttgctc aaatggtcct ttggtatatt tcatttacgc
    12001 atggatctgc aagtttggcg atgttcgtga acagctctgt ttacttgctg aatgatgtcc
    12061 ttgcatttac cgtttcacct tggtataacc aaaaagaacg tgaacgtatg caaaaaatgg
    12121 aagaagaata ctacaacgca caacaacacg cataaaaaaa ctgagcgtgg gacaaaagta
    12181 aagaacactt ttgtctcacg ctctaaacac gtataaacgg cggaatcaga agcaactcct
    12241 tcggaaataa gctgaaattc acaaaaattt gaaaagcaat tttcgtgaat ttcttcttat
    12301 ttcttggagt taaacgcttc tgtcccagcc tctatttcct acgattagtc aagtaaaagg
    12361 tgcaagaaaa atagctcgta aacgaaagcg acaaaatcaa agcacaccaa ataaagcccc
    12421 gttcgtaaaa aattttcgat ctgggcaaag aagtggtata ctgtaagtgg tttagttaat
    12481 ggtccactga gaccgcgtac gcatagtcgt actctgtatg tgccctaacc atagcgtgca
    12541 tacatttcag aagcttgttc atacaagcaa ctgtggcaac cttatctttc ttagggatag
    12601 gttgcttttt taatttgtag taataatcga caatatgatt aggagctgcg cgttgctggc
    12661 gaatcatatt tcgaatggtg aagaaaataa ttttccgtgc tttgggatta ccacgcttat
    12721 tgatgcggtc ttggccagta tacttacctg aatgataccg tcggatgtcg attccgacaa
    12781 aggcattcaa ttgtttatgg gttttaaatc gtgtgatatc tcctaattca ccgagcaata
    12841 aagcggctgt gagtgcgcca atcccaggga acgtttggta caacaaaaag caaggagagc
    12901 cttcggcttt tttga
//
LOCUS       DAMEEU010000078        12737 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.079, whole genome shotgun sequence.
ACCESSION   DAMEEU010000078 DAMEEU010000000
VERSION     DAMEEU010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12737
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.079"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(86..265)
                     /gene="rpmF"
                     /locus_tag="PB779_002315"
     CDS             complement(86..265)
                     /gene="rpmF"
                     /locus_tag="PB779_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HDE0739822.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(323..892)
                     /locus_tag="PB779_002316"
     CDS             complement(323..892)
                     /locus_tag="PB779_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HDE0739823.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1078..1980
                     /locus_tag="PB779_002317"
     CDS             1078..1980
                     /locus_tag="PB779_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HDE0739824.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="PB779_002318"
     CDS             complement(2015..3799)
                     /gene="pyk"
                     /locus_tag="PB779_002318"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HDE0739825.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="PB779_002319"
     CDS             complement(3873..4835)
                     /gene="pfkA"
                     /locus_tag="PB779_002319"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HDE0739826.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="PB779_002320"
     CDS             complement(5003..8317)
                     /gene="dnaE"
                     /locus_tag="PB779_002320"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HDE0739827.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8548..8733
                     /locus_tag="PB779_002321"
     CDS             8548..8733
                     /locus_tag="PB779_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HDE0739828.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8795..9991)
                     /locus_tag="PB779_002322"
     CDS             complement(8795..9991)
                     /locus_tag="PB779_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HDE0739829.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10161..11597)
                     /locus_tag="PB779_002323"
     CDS             complement(10161..11597)
                     /locus_tag="PB779_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HDE0739830.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11890..12699
                     /locus_tag="PB779_002324"
     CDS             11890..12699
                     /locus_tag="PB779_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0739831.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3803 a         2673 c         2250 g         4011 t
ORIGIN      
        1 tattttttat ttaccgacta caaaaaaata aacctcaagg ctccatggtt agccttgagg
       61 ttttacattt tctaattaaa atgtattaag cttcttttga cattacgtcc ttaccatcat
      121 agtaaccaca atttgcacat acgtgatggc tttttttcat ttcaccacag tttggacatt
      181 cgtttaaccc tttgattgtc aatttgtagt gtgtacgacg ttttgctttt ttagcttttg
      241 atgttcttct agctggtact gccattttgc tacacctcct tgtaaagtct tgtatctaaa
      301 ttagacacaa tatattccaa tcttacttgt tatcgtcgtc ttttgattta gaatcaaaaa
      361 gttcagatag ttttgcaaga cgaggatcaa ttttattctc ggcttcttcc atttttctgc
      421 gctggtattc ttcttcggaa acaacttccc aatcattgcc ttttggaagt tctgttgctg
      481 cttcctcttc ttttgtcaat acccgcattg gaatcgccaa taagatgttg tcttcaatcg
      541 actctgctaa attcaataat ggaccttcaa ttagcaaaat ctcatctgca gacatttgtt
      601 catctctact ttggaattgt tcttctgtca tgaatacttc gtctacagaa aaatccatgg
      661 gcagttcaac aggttctagt gaacgtgttg aaggaactgt caaagtcgtc tgcacagtgt
      721 aatgaacgat atagcctttc ttatcaactg agaccaaacc ttcgacttcc actggcgcaa
      781 catcaagtat taaattgtct cgcttcatga gagcggcttt caagtcgagc gtctcatgaa
      841 aagttaacgg tgtctcctgg tattttctca attccaataa agaccatttc atttttcatc
      901 actcctaagc aacaaaagca attatacagg gcaaaaagca tgttgtcaat gaaattttct
      961 tgacaccttg cagttcataa aaaaacagaa aaatctttat tagaaagcct ctgtttgcta
     1021 tcatcctcag aatcatttac aataatcatt attccattaa aggagcggat gatcttcatg
     1081 aacacgaaag atatcgaata ctatgtccaa atcgtcaaac aaaaaaattt tacgaaagtg
     1141 gctaattatt tccgtgtgag ccaacctact attacatatg cattacaacg tcttgaaaaa
     1201 gagtttgaca ccgtacttat tacaagagat cgatcgcatc acgaattaat cgtcacgcct
     1261 tctggaaagc agctgtttct ccatgcacaa accattctcc aagagatttc tactgcaaga
     1321 gctgaaatca ctcagttgca aaagaaaaag cttcgttttg gcatgcctcc tattatcggc
     1381 aatgaatact ttcctaaact gtcaagttac tttatcaagc atgaattgat gaatcaaatt
     1441 gagattaccg atggaggctc tcgggactta tacgggatga tccgacaagg gaggatcgat
     1501 ttagctgtat taggctcaac acagccaatc gtggatcaat atttagaaac agagttactt
     1561 ttggacaaac gtttcatgat cgtcgtgcca cctacacatc ctctttccaa gcaggatact
     1621 gtctctttca aagatatagc agatgaacag tttgtactat tgaacgaaca ttatgtccac
     1681 cccgcagcat tcactaagct ttctaaacaa acacatactc atccaaaagt tgtttatcaa
     1741 agcaatgact tgacgatttt aaagagtatg gtccgagaaa atgtgggtat cggttttttg
     1801 gcagagattg ctgtccatcc tgaagatcat ttagtttgcc tccctctttc agatgaagtt
     1861 cagcctcgct tcttgatttc attggcaaaa cgaacacagc agatcgtcac gcctcttcaa
     1921 gaacaagtag tccaagttat ccatgaattc gttacagcac aaaaaaacag ctcttcgtaa
     1981 aagaagagct gtttttattt tttattaagc taaattagat agctgttgtt tcgccacggt
     2041 aaacgatgcc gcgacgtgaa tcaacggtaa tcaattcacc ttctgtaatt gttgttgttg
     2101 cgcctttagc accaacgatt acaggaatat cttgtgcaat tcctacaact gcagcgtgag
     2161 aagtcaatcc gccttcttca acgataacag cagctgcttt ttcgattgca ggcatatatt
     2221 ctttgtcagt tgatggtaca actagaacca ttccgtcttt tgcttttttt acagcttctt
     2281 cagcagatga agcaataact gcatttgcaa cgacagattt ttgtccaacg ccttgagctt
     2341 ctaataattt agaaccaatc atttgaattt tcatcacgtt agttgttccg cgttcaccaa
     2401 ctggtacacc agcagtgatc aagattaaat cgccttctga tgcgaaacct aattcaacag
     2461 cttttttagc tgctagttca aacatttcat cagttgttga tggtttttca gcaactgttg
     2521 ggtaaacgcc ccagtttaac atcaaaccac gttttgtgcg ttcgtcaaaa gtaacagcca
     2581 agatatctgc atctggacga tattttgaaa tcatttttgc agtgtatcct gattcagttg
     2641 cagcaacgat tgttttcacg cctagatttt ttgcagcacg agctacagat aaaccgattg
     2701 tttcagttac atctgtttta tcgaattcgt tcaattggaa tgtacctaat tctgataatg
     2761 cattttcagc ttcttggtcg atacgtgcca ttgttgaaac agcttcaact gggtagtccc
     2821 cgtttgcaga ttcaccagat agcattgttg catctgtgcc atcaaataca gcgttagcaa
     2881 cgtcagaagc ttccgcacgt gttggacgtg ggttttcttg cattgattct aacatttgtg
     2941 tagcagtgat aactgggata ccagcagcat tacatttttt gataatgcgt ttttgaacca
     3001 ttggtactag ttcagctggg atttcaacac ccatatctcc gcgggcaatc ataacaccgt
     3061 cagaaacttt gatgatttcg tcaatgttgt cgataccttc ttgagattcg attttaggga
     3121 agatttgaac atgagtcatg tctttttctt ctaagatttc gcggatatct agaacgtctt
     3181 gtgctttacg tacaaaactt gcagcgataa agtcgatatc gttgtctaaa ccaaaacgaa
     3241 tatcgtcagc atcttttgga gtaatacctg gcaaactaat agaaacgcct ggtgcattta
     3301 cccctttacg tgatcctagc atacctgcat ttttaacttc tacgactaat tcacggtttg
     3361 cttcgtcttt ttcaatgatt tgcatatcga tcaaaccatc atcaaataaa atgtgtccgc
     3421 caacgtgaac atcgtcaaat aatcctgggt aagtaaccgc gattttttct tttgaaccta
     3481 catgttcagg atccatagag atgcgtgttt gatctcctac ttcaaatttg atgtatcctg
     3541 cacgaccaaa atcagcttct gttgtgcctt gaacagttgt acggatttca gctccttttg
     3601 tatctaaaag aataccgaca tcttttcctg tctttttaac tgcttcacgg accatagtca
     3661 tacgtgataa ttgttcttca tggtcaccat gagaaaaatt aaagcggaag acatttgccc
     3721 cagattcaat caattgagaa ataatttcta ctgagttact tgctggtcct aatgtactaa
     3781 cgattttggt ttttttcatt taaaaaactc tcccattcaa ttttgtttat ttaaagctgt
     3841 acacagctta aatagcttgg tttctttcac tcttaaaatg aaagtgaatt atttagatca
     3901 tatagtgata agtctggttt atgtttgttg ttttcaagtg tatcaatgat gtcagacgca
     3961 acgatttcgt tgtcatggat accgacacat aatccacctt ttccttcttg aagcaattcg
     4021 acagcgtaag caccgaattt acttgccaac acgcggtcgc gtgcgcttgg tgctccacca
     4081 cggacaacgt gtcccaagat agatacacgt gtatgatagt caccaaattc tgaaagtttc
     4141 tcagcgaatt catttccgcc cattacacct tcagccaaga tgatcaagca atgtttcttc
     4201 ccgcgatcgc ggccttcttg gattttttta gcaactgaag ccatatcaaa atcatgttct
     4261 gggatgatga tttcatccgc tccgccagcc acacctgacc ataaagcgat gtctcctgca
     4321 ttgcgtccca ttacttcgat aacgaatgta cgaacatgag aagtcgctgt gtcacgaata
     4381 cggtcaattg attctagtac tgtattgatt gctgtatcaa aaccgattgt gaaatcagtc
     4441 ccaggaatat cattatcgat tgttccagga atacctactg ctgggaaacc gcgttttgtc
     4501 aaagccattg cgccatgata agagccgtct cctccgataa ccactagacc ttcgattccg
     4561 aattttttca attgttcgat tccttttaat tgaccttctt cagttgcaaa ttctggataa
     4621 cgtgcagaat acaagaatgt accaccacgt tggatcttgt cacctacatc tgccacatca
     4681 agacgacgaa tatctccagc aactaaaccg gcaaaaccat aattgatccc gtatacttcc
     4741 agtccttcgt aaataccttt acgaacaacg gcacgaacag ctgcattcat tccaggtgcg
     4801 tctccgccac tggtcaaaat tccgatgcgt ttcataataa acattcacct cattaaaata
     4861 ctttatccta agtatgactt aggtttacaa ccatttttgc gttaaccacg actaacattc
     4921 taacattatt tttctcactt gtcttgattt acggataaaa aaatgaaaaa aaatgaaagc
     4981 aagtagtatt ttttaccgta agttatttga aaaccacatt atcttcgcca agcagataaa
     5041 taagttgccc ctttatactc ttgctgtcat ccacccaata agcatctgac agaactactt
     5101 ttcgttgcgt tttttcgtga tacataacta ctggtatata tcctgggtgt ttctgaaaaa
     5161 tcacttgtaa ttgtttcatt atctcgggat cttcccgttc ttctgtaata cgcaaatagc
     5221 aagtttgtga aggatactgg gcttctaact ggttaggatc agcaaagctt tctccaatta
     5281 gttgcagttc ctgattatat ttgctgattt cgctccgccc ttgaacaaag atcactcgat
     5341 caacggcaaa caaattacga tatttacgat aaagagttgg aaaaactgtg acagaaattt
     5401 ctccactact gtcggttcct tcaacaaagg ccatcagttc tccttttttt gtccgaattt
     5461 ctctaacttc cttgatcatc actaataaat tgactggttg attagggacg atatctgtaa
     5521 tcagctgaac ttgtttagct aaacgaagac gatcaaaccc ttctgcagga tgacctgaca
     5581 aataaatacc taagtactcc tcttccagct tcaagcgttc ttctagtgta tagtcagcga
     5641 cttcttcttc ttttaatgcc atgattccca gcaagtcaag acttccacca ctgtaaacga
     5701 tattttggat ttttccttcg agatcaagca tcaattgttt cctgttagga gataattcat
     5761 caaaaactcc tactgctgtc agtgattgca gtaactctaa tttcagccaa cgcttatcga
     5821 tccgtatgag gaattgatcc actgactgga acgggccatt ttgttttctt tcgtttaata
     5881 tatcttctac aaaatcacgc cgaatacctt ttatcgctgt cagtccgaat ctgatttctt
     5941 ccttattgac caactcaaaa ctggaattac tttgattaat ggacggcgag gaaagtttga
     6001 gtttattttt acgtgcttct gcaatatatt ctttcaattt tgatgtgtta tgccgaacag
     6061 aattcatcag gctggtaaag aaagcacctg gatgatgggc ttttagatac gccatttgga
     6121 atcccacgaa tgaataagca aatgcatgtg accgattgaa tccatagttt gcaaattttt
     6181 cgatatattc atatacggtc gctgctgttt tttccgaata tccctgttgt aatgctcctg
     6241 atacaaaatg cgacttttct tcatctaata cgtctttttt ctttttactc actgcccgtc
     6301 gcagaatatc tgactgccct aatgtaaatc cagccatagt cgaggcgatc tgcatgattt
     6361 gttcctgata gacgatcact ccatatgtgt ttttcaaaat cgggatcagt gaatcatctg
     6421 ggtagcgaat ggcttctttt cctttcttcc tggcaatgaa ggtatctata ttttgcatag
     6481 ggcctggtcg atacaatgca ttgactgcgg caatatcttc gatgttttct ggatctaatc
     6541 ttcgtaaaac gttccggata ccagcagatt caaattgaaa tactcctgag gtttcgcctc
     6601 gttgaaacaa gagcagcgtt tttgcatcat ttagcgggat ctcttttaat cggatctcat
     6661 acccttctac tcgcttaaca gctttcaaag taaaatcaat aatcgataag ttgcgtagtc
     6721 ctaaaaagtc cattttcaaa agaccgattg cttctacctc attcatcgta tactgggtca
     6781 gaaaagcttc atcagaaccg cgttggagcg gaactagttc aagtagattc ttatcgctga
     6841 taactacacc tgctgcgtga gtcgaaacat gtcttggcaa tccttctaaa atcactgcag
     6901 ttttgaataa aagttggttt ttttcgcttg cctgaactaa ttctactaat tgatgcgaag
     6961 ttttataagc ttgggtcaat gtgattttca attgattggg tattgctttt gaccagcggt
     7021 ttgcttcact ttgcgataaa ccaaacactc tagctgcatc tctaagaacc atttttgctg
     7081 ccattgtgcc aaatgttgcg atttgtgcca tatgatattg tccatacttt tctcgaacat
     7141 aattcaatac ttcttcacgt cgattgtcag gaatatccaa atcgatatct ggcatcgtaa
     7201 agcgttcggg gtttaaaaag cgttcgaaca gcaaatcata ttctaatgga tccacatctg
     7261 tgatttctaa cacataggct actaatgaac ccgcagcaga accacgacct gcaccggtaa
     7321 cgattttgtt tctatgagca aaagccatta catcccatac gatcaagaaa taatcatcga
     7381 atcccatttg atggatgaca gataactcgt agtccaaacg ttcttggtat tcctttgtat
     7441 agtcagtgat tcggcgttcc acttgcgaat agcataactc tcttaaatat tctccagctt
     7501 gttttccatt aggaactgga taatgcggaa gtaatttctg atggaactgg aattcaaatg
     7561 aaatcgattc agctaaacgc tgggcgccta ttacagcttg ggaaagaccc gctttttcga
     7621 atcgtttgat catttcttgt tctgaaagaa gatagacatt tgctgttagt ggtaaagatg
     7681 cagataaatt ttctaaaggt atttggcttc cctctttgat atgtttcatc acttcaagtg
     7741 caaaaagttc ttcttgttgt aaactagcga tgggatgtaa tgcacaaagc gaataatttt
     7801 cttttatcac atactgatac cattcaggca attgatcagg cgtgttttct gtcaagccga
     7861 tataaaaatt tctagtaaaa acattttcaa gtaaaaactg ccaatgaccg aaaaagttat
     7921 cctctttatt gaaagcctca gaaacagaat gatttgccgg aacaacaaac gctagatggt
     7981 cggtttctgt catttctgca agttccaatt tttcttggat catttttcgg ctggaaagtt
     8041 tcatcagctg ctgataacct atttcatctt ttgcgtacgc aagcaagcca taattttttt
     8101 cttcataagt ataactaaga tgtaatccaa tgattggctg tactccttct tctacacaaa
     8161 tacgatagaa ttcaggtgca ccgtataaga catctttatc cgttatggct aatgaagtgt
     8221 agccttgttt ttttgcttct tgtacatatt ctcgaatacg tatcgtactt tgtaaaagag
     8281 aataagaagt aattgtataa agttgtggga aaaacatctt gcattccgcc ttttttttcg
     8341 ttaaaattca ctagcgttaa aaggtttgat ccttttactt tcattaagat agcaggcgct
     8401 gaagttgatt attccacttc atttgcttgc ttgtaatctg taggaatgag ttctttcgca
     8461 agaactcaaa ttttattgag atttggtctc gtttctttac attcaaagaa aatctggtaa
     8521 aattaagata gaaaagaggt gttctttatg cgatatatcg ttacattatt ctgggctgtc
     8581 gttctaggtc aagtagtcgg ttatattggt gctgcattaa caagcggaac atatgatttt
     8641 actttgacaa caatcatttc attcattgcg ggtgtcatta tccttttgat tggtgcagtt
     8701 gcgccaagaa aagaaacctc tgcccattcg taaaaaaaca gccaagagct tgagatttct
     8761 caagctcttt tttattttct actcctcacc accattataa tctgctgcga agaactttac
     8821 gaaagttgaa taaagaaaga agaatatttg acagaacaaa caaacttgtc acaataaaaa
     8881 cagcactgta attataagca tgcgcgactg tcgatcctag catgggacct aaaacttgtc
     8941 caaagttgct aaacatctga ttgtagctat agattcggct gactccttct tgaggcgtaa
     9001 tcttactgat cagtgtattg acagaaggca tcaaagcgcc agttgaaaag cctaaaataa
     9061 agcgaagtat acctaattgg agcggtgtag tgacgaatgc cataggtaaa taacagcaaa
     9121 atgataaaat gagtcctcca attagaactt tttgattccc aatcttatcc cctagttttc
     9181 ctagtttcgg tgaagaaaag acagcggaaa caccagctat cgaaacaatc aagccgctga
     9241 caaaaaggat attttctgta cttccgctca attcacgaat atataaggtc aaaatagggc
     9301 tgatcgtagt gattcctatc tgtaaaatca aggtcgtaat gaagagaccg atcaaaatag
     9361 agagatgatc catttttgaa aaaatttctt tggtgcttat cagatctttt ttctcgattg
     9421 gatggaaatc ttctttgact aagaaaatgg tcaataccgt tgtgatcatc aacaaagccc
     9481 ctgtgatcaa gaatacattt tccataccaa accactgagc cagtgcaccg cccattgaag
     9541 gtccgatcag atttccagca atcgctccgg tagacaatgt tcctaacgcc catccgctct
     9601 tttctctagg tgcctgtgaa gcaatcatcg ctgtggcatt tggaatatat ccagacaaaa
     9661 tcccattcca aaaccgcatg atcaaaagcc aatacgcgtt tggtacaaaa gccaaagatc
     9721 ccattgttaa tgtcatccct gctgctgcac ggatcatcat gagttttcgg ccttttcgat
     9781 cagctagatt tccccagatt ggtgcaacca cggcagatgc aaaagcagtc acagagattg
     9841 ctagtcccga aaacaattcg atttgatctt ttggtgttcc tagttgctca acataaactg
     9901 gtatgaatgg cataactaaa ctaatacttg caccagtgaa aaaacagcca atccacgcaa
     9961 tcactaaatt ttttctccaa ttaatctcca tctatcatcc ctctttcgtc tcttttatca
    10021 tacctatttt cgaataaaca agcaacgatc tcgccagtaa aaagagaaaa atcccgcaaa
    10081 ggtcatttta tatgtaacgt tctttttatg taaaacaaaa agagatcaga acaaatactg
    10141 ttccaatccc ttctctttag ttaaattgtt gctagaatga tgaagttgat aatgaataaa
    10201 atatcaacga tccacaaagc aacagaaact tgattgtatt ttcctttgat tactttcaca
    10261 attgtataga aaataaatcc tgctgcaatc ccataggaaa tgctatagca caatcccata
    10321 aagatcgatg caaagaaggc cggtaaagct tcttccatat ctagccattt gatgtctgca
    10381 aaagaagcca tcatcattac tccaactaaa atcaatgctg gcgcagttgc ttgatttggt
    10441 acaatggcga tcagtggaga gaataaacta cttaatgcga atagcactgc cactactact
    10501 gaagtcaaac cagtacgtcc accggccccg atcccagctg cagattcgac ataagttgtt
    10561 gtattcgatg taccaaagat agcccccaca gaagtagcga tcgcatcggc aaatagtgct
    10621 ttatccattt ttgttttgaa cccacgacca tcttccaacg cgatctcgtc ttcttttgag
    10681 aaaatacctg tgcggcgtcc tgtaccgata aatgttccga tcgtatcgaa agtatcagat
    10741 aaactgaatg cgatgatcgt catcaatact tgaggaatct tggaagaatc actgaataaa
    10801 gattgcatgc cttcagaacc aaatgctgca ccgaaagttg ttcctaattc tttaaatgaa
    10861 ttacctaacg aattcgtttg ccaatcaatg gaacttaaat caacaacacc cataaaaata
    10921 ccaaggactg tggtcgctac gataccgata agaatagccc cacggacatt ttttacaact
    10981 aaaatggctg tcagtaccaa accaatcaca gccaataaga taggagcgtt gtcaaagttg
    11041 gctaacgcag ggacgattcc accatttatc gtaacatttg tcgcttttcc gccttcaacg
    11101 acagagctcg aaatagctga ctggtctgct gaaaaagata agaatcctgc atttttgatt
    11161 ccgacatacg caacgaaaat accgatcccg ccaccaatcg catgttgaag actttcggga
    11221 atcgcccgaa taatcatttt tcgaatattt gtgacagtaa taaaaatatt gattaatccg
    11281 caaataaaca ccattgccaa ggcttgttgc caagaataac caagcccaaa aacgaccgta
    11341 aaagtgaaaa atgcgttcaa tcccatacca ggtgcctgag catatggtac atttgcgaac
    11401 aatcccatta ccagcgtacc aataatcgat gcaatgattg tcgctagaaa tactgcttgg
    11461 aagggcatac ctgatgctga caaaatcgtc ggatttacga ataagatata actcatggca
    11521 aagaatgtcg ttactcccgc cattatttca gttgatacat ttgtattgtt tttctttaaa
    11581 ccgaaaaact tttccataaa aagttccact ccctgaattt ttttctgatg gaaaactata
    11641 ataataaaaa ataagtaaaa tagggcaaat ccatcgaaca atttcaaatt atatagacgt
    11701 ttcattcgct tttcaacgtt tttttaacaa aaaaagcgaa aataatactt aacgttcgtg
    11761 tttagcttat gtttagctat ttatatagcc ataactgtag tttttgttag gaatagctga
    11821 ttgctcttgt taattaccta aaatatgcta gactaaaaca aatgctagtt gaggaaggaa
    11881 ggacccttat tgaataaaaa attaattgcc atcgatctgg acggaactac cctcaatcaa
    11941 gattcgatga ttacatctaa aacaaaagag actctaaaaa aagcaatcaa tgccggtcat
    12001 catgtcagta ttgctacagg acgcccattc cgaatgagcc atcagtttta ccaacaatta
    12061 gaattaacaa caccgatggt taattttaac ggcgcattag tacacatccc taatcagcac
    12121 tgggatggtg aaagagaaac gttgatcaat cgtgaaatcg cttttgaaat cttatcgcaa
    12181 aaaaagcagc taaatttaga ttttatcgct gctgaaaatc gtgatacttt ttttattgac
    12241 agttttgatt tctttgatga aaaaattttt gcttcttctc gtccaggaga gaagaatttg
    12301 ctttctccta aaaatttgac gacaaatcct acatctttgc ttgtccgaac agacaaacgt
    12361 tttgcaggag ctgtatctgc tgaattaaca cgtcaatttg gcagttatgt cgatgttcgg
    12421 acatggggtg gacctactgc catcttagag attgtttcaa aaggaatcca aaaagcaaaa
    12481 ggcgtgcaag agattgctaa ctacctgtct atcgatcaaa aagacgtcat tgcctttggt
    12541 gacgagcata atgatttgga attgttggat tatgcaggtt ggggagtagc tatggctaac
    12601 ggtactgacc aactcaaagg cattgcaaat gatgtcactc ctttgagcaa tcaggaagac
    12661 ggtttagctg tttatctgga aaaactactt aaactataat agagaattag attccacaaa
    12721 aaagaggttg tgacaat
//
LOCUS       DAMEEU010000079        12711 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.080, whole genome shotgun sequence.
ACCESSION   DAMEEU010000079 DAMEEU010000000
VERSION     DAMEEU010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12711)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12711)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12711
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.080"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..577)
                     /locus_tag="PB779_002325"
     CDS             complement(<1..577)
                     /locus_tag="PB779_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDE0739832.1"
                     /translation="MNHKLSETEQYLWNFIEHLILEIPNYSIVKLSEQANVSTATIVR
                     TMKKKGYEGFTSFKHHLKEGENKNINFSFLDKVDKGIRRAILKNEQEVVRTINMLEIG
                     NIEDAIQRIKFADRVFVFARGFSEMIGQEMLVKLQLTGKNCQMHTDPEIIKSISRKLT
                     KKDSVIFVSLNGEKTNKNIKNKIYVFIFQFFK"
     gene            719..1651
                     /gene="pfkB"
                     /locus_tag="PB779_002326"
     CDS             719..1651
                     /gene="pfkB"
                     /locus_tag="PB779_002326"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HDE0739833.1"
                     /translation="MSIYTCTMNLAIDLFIETDEMHPFMVNRTKEDDIQANGKGVNVS
                     LVLKMLDFPSTALGFSAGFTGKYIEDYLQQKQIQTEFIEVPGMTRINVFTQVNQTGEE
                     YKLVNQGPEIPQTAVHNFLNQIRALQAGDYLCVSGSLPRGLSPKVLIEISRICLIIDS
                     SDQEVMDCLPYRPFLLKPNEEELSSWFGRKMVTDEDYFVYGQRLVESGAENVLLSLGE
                     KGAILFTKDRVIRGNSPKGKVVNTACAGDAMLGTFLAGYMNRRSLDETLRKSIAAGSS
                     TAFRKGLTDFLDVEELSKQIKIKEERFERWENIN"
     gene            1633..3096
                     /locus_tag="PB779_002327"
     CDS             1633..3096
                     /locus_tag="PB779_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0739834.1"
                     /translation="MGKYQLIAATGCPTGIAHTYMAQEALEQAARKKGITIKVETHGQ
                     IGIENELTAEEIKQADAVIIAADKDVHSERFVGKRVIDVSVSTGIKDAQRLIDEALAG
                     KGTVLADNEAADTLEPEAISGANFGRSIYKNLMNGVSHMLPFVVAGGVLIAISFAVWG
                     IYSSDPDHAQYNATAAMVKAVDDAAMGMMVPVLAAYIAEGIAKRPGLVVGFVGGIVAM
                     NGGTGFLGGILAGFLAGYFILFLQKLLIILPKQLDGLKAIVLYPVIGVAFIGIVMSLL
                     AGPMKAINEGMMSFLAGFEYSNPLVLGVIVGCMCAFDMGGPVNKAAYVTGTALLTQGN
                     TTFMAGASAACIAPPLITGFATLLFGKYFDTNDRNAGLVNFILGSTHITEGAIPFAAK
                     DPIRVLPTMMLGSSIAAVLTYLFGVQVPAPHGGFLVLPVVTGKIQWVTAILIGSIVGG
                     VILGLIQKKRVTDKDKKRDNKATNRTVIEEGRAGGLS"
     gene            3093..3551
                     /locus_tag="PB779_002328"
     CDS             3093..3551
                     /locus_tag="PB779_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HDE0739835.1"
                     /translation="MTIIHEENIFLQQPLDNQEEAFKFLAKQTFCLGIAHDEKEVYQK
                     LLEREKEGTTGIMSGFAIPHAKSQTINEPSLIIVTLKKGIEWNSLDRQSVDFIFALFI
                     PDSEAGTTHLKLLSLVARSLMRKEVTEQLRAAKSKIEIATILTKEIGEDI"
     gene            3548..4522
                     /gene="lacD"
                     /locus_tag="PB779_002329"
     CDS             3548..4522
                     /gene="lacD"
                     /locus_tag="PB779_002329"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDE0739836.1"
                     /translation="MKKMSIEKQERLKRLTDEAGIISALAIDQRGALKKMINQYKEAT
                     SEDIIQFKQMVSQYLTPYASAILLDPEYGLPAAALREKECGLLLAYEKTGYDAKMPGR
                     LPDLLNSWSVKRLKEVGADACKFLLYYDVDEPVEINVQKQIVIERIGSECEAEGIPFF
                     LELLSYDATIGDPSSLDYAKVKPHKVIEAMREFSKERYQVDVLKVEVPVNMRFVEGYG
                     QDTCYSQAEASAYFYEQSKVTEQPFIFLSAGVSAALFQDTLRFAKQSGSTFNGVLCGR
                     ATWAKGVAPFVTEGEEKASSWMLEEGKQNIKELSTLLEETATSIYVNK"
     gene            4963..5691
                     /locus_tag="PB779_002330"
     CDS             4963..5691
                     /locus_tag="PB779_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739837.1"
                     /translation="MESSNKGKSLYYQLVDLLKDRIETQMTPHDKLLSERELCQHYGV
                     SRTTVRLALQELENQGYIYRRHGKGTYVSDLSDKSSNLAGAYSFTEEMREIGRVPKTV
                     ILEFRQMEANKRIAKNLNIHLGETVFKLKRLRLADEEPLMVERSYLPAKLFMGLDLPL
                     LESKPLYDVFSQDYEQQVQLADEEFYASIVQKKDAVVLRIADGAPVLHLTRITYNVKN
                     EIIEYTDSVARADQFHYKIRHIRK"
     gene            5709..6905
                     /locus_tag="PB779_002331"
     CDS             5709..6905
                     /locus_tag="PB779_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0739838.1"
                     /translation="MFELSKNKLKQIGAAITTQEIKQQPDLWKETIDRLMQSQENLAL
                     FFDQIKKEANGRRIRVIFTGAGTSQYIGDTLLPYLNEHGDNQFFIFHSFGTTDIVASP
                     KEFLFPNEPTLLVSFARSGNSPESVAAVQIANEQVETLFHLTITCAKEGMLAKNAQDD
                     KQNYLLLMPERANDAGFAMTGSFTCMLLSALWIFDQTAMEKKERYLEQLVKIGQDLLS
                     RDQEIQKLLPDFFERIAYLGSGSLAGATREAQLKILELTAGKVATIFDSSMGFRHGPK
                     SFLNSETLVVGFVSNQPYTRNYDLDILEEIKEDRVTANVIAIAQPGTIDFSGMTVLLE
                     DSVSKLPDAYLALAMIMTAQIIALYTSIKVANKPDTPSPTGTVNRVVKGVIIHKYETE
                     GEMTDE"
     gene            6898..7893
                     /gene="lacD"
                     /locus_tag="PB779_002332"
     CDS             6898..7893
                     /gene="lacD"
                     /locus_tag="PB779_002332"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDE0739839.1"
                     /translation="MNEEKNRAMERLSTKDGIISALAIDQRGALKKMIKSLGKEPSED
                     QISEFKELVSAELTPYASAILLDPEYGLPAAKVRAKETGLLLAYEKTGYDATTPGRLP
                     DLLADWSSLRLKEQQADAVKFLLYYDVDEAPEINHLKHVFIERLGSECEGENRPFYLE
                     LVSYDAQISDSSSPEYAKVKPHKVIEMMKEFSDPKYKVDVLKVEVPVNMNYVNGYSTG
                     EFIHSKEEAAAFFKEQSEATPLPFIFLSGGVSTELFQQTLIFAHESGSTFNGVLCGRA
                     TWKDGVKAYVENGKDGAIHWLRTNGRENIETLNKVINETATPWFNKTKSKKVKMK"
     gene            7890..8831
                     /locus_tag="PB779_002333"
     CDS             7890..8831
                     /locus_tag="PB779_002333"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose kinase"
                     /protein_id="HDE0739840.1"
                     /translation="MITTVTLNPSIDIAYTIEELNLDKVNRVETVNKTAGGKGVNVAR
                     VLNLLGEEVIATGLIGGQHGEYLKNQLDQLGIMHQFVPIKGETRDSIAILHSSRQTEL
                     LERGPFITKKEQQTFTDHFEQLLEISDIMTISGSLPQGCPLDYYKQLVALADKKGKDI
                     LLDTSGKFLLEVLEGKEKPLLIKPNLEELGELIGQRICSSIQLEKIQSLLAHPIFEGV
                     PWVVVSLGERGAVAKVAQCFYEVIIPKISVVNPVGSGDATLAGSAHALSKRQSIEEIL
                     AFSMACGMANAQQEKTGWIDPMKVTMLMKHIQVKKIK"
     gene            9007..9486
                     /locus_tag="PB779_002334"
                     /pseudo
     CDS             9007..9486
                     /locus_tag="PB779_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632653.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
     gene            9499..10389
                     /locus_tag="PB779_002335"
     CDS             9499..10389
                     /locus_tag="PB779_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739841.1"
                     /translation="MDIQWWQILLLTLYAGYQILDELQIYSSMSAPVFAGLYAGLVMG
                     DLNAGLIIGGSMQLTVLGVGTFGGASKIDANSGTILATAFSISLGMNPEQAIAAIAVP
                     VASLMIQLDILARFANTYFAHRIDRHVEDMNYQAIERNFLMGALPWSLSRMIPVFLAL
                     AFGGGLVENVVSVLNGNLKWLGDGLSVAGAVLPAVGFAILLRYLPVKKHLSYLILGFT
                     ITALLATLFSNVQLLGTSVASVVKDLPATFNSLPMLAVALIGLALAMISYKNDQNKDH
                     QPLASEPSHSVEGEIEDDEI"
     gene            10376..11185
                     /locus_tag="PB779_002336"
     CDS             10376..11185
                     /locus_tag="PB779_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDE0739842.1"
                     /translation="MTKSNYKLTKEDFKQINRRSLFTFQLGWNYERMQGSGYLYTILP
                     QLRKIYGDNTPELKEMMKTHTQFFNTSNFFNTIITGIDLAMEEKEGIASKETVSGLKA
                     GLMGSFAAIGDSVFAALIPTIFGALAANMATDGNPIGVFIWIFAQIVVMVFRWKQLEF
                     AYKEGISLVTTMQSRLTALTDAATLLGVFMVGALVATMINVKFSWAPTIGDVTLNMQN
                     YIDMILPKILPAGIVGGVYWLLGKKNMTPTRAIFIVLIVCVALSALGVISK"
     gene            11199..11600
                     /locus_tag="PB779_002337"
     CDS             11199..11600
                     /locus_tag="PB779_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDE0739843.1"
                     /translation="MSRQLVLISHGKFCEELKKSTEMIMGPQEDIYTLPLLPEDGTET
                     YKQKFLTVTDSLNDFVVLCDLLGGTPANIISKLIMEGQQITLYAGMNLPMVIEFINSQ
                     MIGSEPEFVRAGCESIVSVNELINGIAEEEE"
     gene            complement(11646..12596)
                     /gene="yidC"
                     /locus_tag="PB779_002338"
     CDS             complement(11646..12596)
                     /gene="yidC"
                     /locus_tag="PB779_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HDE0739844.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVVIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPANNKQATKQIKQPKNSTNNKGRNAGKQQKRK"
BASE COUNT         4069 a         2057 c         2779 g         3806 t
ORIGIN      
        1 atttaaaaaa ttgaaaaata aagacataaa tcttattttt gatgttttta tttgttttct
       61 caccgttcaa agaaacaaaa ataacgctgt ctttcttagt tagtttccga ctgatgcttt
      121 tgataatttc tggatcagta tgcatctgac aattttttcc cgttaattga agttttacca
      181 gcatttcttg gccaatcatt tctgaaaatc ctcgggcaaa gacaaaaacc cggtcagcaa
      241 atttgattct ttgtattgca tcttcaatgt tcccgatttc caacatattg attgtacgta
      301 ccacttcttg ttcatttttt agaatggctc ggcggattcc tttgtctact ttatctaaaa
      361 atgaaaaatt gatgttcttg ttttctcctt cttttagatg atgcttaaac gaagtaaacc
      421 cttcatagcc tttctttttc attgtccgca caatggtggc tgttgagaca tttgcttgtt
      481 cacttagttt cacgatggaa tagttaggga tctctaggat gaggtgttcg ataaagttcc
      541 agaggtactg ctctgtttca cttaatttgt gattcatatt ctttccttct ttcaccaaaa
      601 gttagttaaa aaaagcacga cgagtttata aatgtaaagg ttttctttgt gttgggacga
      661 ttaagaaaac attttctatt tcgcgtattt cataatagaa tcaaggaggt cgttggttat
      721 gtctatctac acatgcacga tgaatttggc aattgatcta tttattgaaa cagatgagat
      781 gcatcctttt atggtaaacc gcacaaaaga ggatgacatt caggcaaacg gaaaaggggt
      841 gaatgtgtca ctagtattaa agatgctaga tttcccaagt acggcattag gtttttctgc
      901 tgggttcaca ggaaagtata tagaagacta tttacagcag aaacaaatcc aaacagagtt
      961 tattgaagtg cctggtatga cgcgtatcaa tgtatttaca caagtcaatc aaacgggaga
     1021 agaatacaaa ttagtgaatc aaggacctga aataccgcag acagctgttc ataatttttt
     1081 aaatcaaata agagcattac aagcagggga ttatctttgt gtttctggga gtttaccaag
     1141 agggctgtct ccaaaggttt taatagaaat cagtcggatt tgtttgatta ttgatagtag
     1201 tgatcaagaa gtcatggatt gtttacccta tcgaccgttt ttgctgaaac caaatgagga
     1261 agaactttct tcttggttcg gacgaaaaat ggttacagat gaagattact ttgtttatgg
     1321 acaacgacta gtagagtcag gcgcagaaaa tgttttgtta tccctcggtg agaaaggagc
     1381 gattcttttt acgaaagaca gggtgattcg aggaaactcg ccaaaaggaa aagttgtcaa
     1441 tacagcatgt gcaggtgatg ccatgttagg cactttttta gcaggataca tgaatcgacg
     1501 atcgcttgat gaaacgttac gtaaaagcat agcagcaggc agctctactg cttttcgtaa
     1561 aggactgact gattttttgg atgtggagga attaagtaaa caaatcaaaa tcaaggaaga
     1621 gaggttcgaa agatgggaaa atatcaacta attgcagcaa ccggttgtcc gacaggaatt
     1681 gcgcacacct acatggcgca agaggcatta gagcaagcag ctaggaaaaa aggcatcacg
     1741 atcaaagtgg agacccatgg acaaattggg atcgagaatg aattaacggc tgaagaaatc
     1801 aaacaggcag atgctgtcat tattgccgca gacaaagatg tccattcaga aagatttgtg
     1861 ggaaaacgag tcattgatgt ttctgtcagt acaggaatca aggatgcaca acggctgatt
     1921 gacgaagcat tggcaggaaa aggtactgtc ttagcagata atgaagctgc tgatacttta
     1981 gaaccagaag cgataagtgg tgctaatttt ggtcgtagca tctataaaaa tttgatgaac
     2041 ggtgtctctc atatgttgcc tttcgtggta gctggcggag tattgattgc tatttcattt
     2101 gccgtttggg gaatctattc ttctgatcca gatcatgcac aatacaatgc tacagcggca
     2161 atggtaaaag cagttgacga tgcagcaatg ggaatgatgg ttccagtttt agcagcttat
     2221 attgcagaag ggatcgcgaa acgtccaggg ttagtcgttg gatttgttgg tggaatcgta
     2281 gccatgaatg gcggtactgg atttttagga ggtattttag ctgggttctt agcaggttat
     2341 tttatcttat ttttgcaaaa gctactgata attttaccta aacaactaga tggcttgaag
     2401 gcaatcgtct tatatccagt tattggtgta gcatttattg gcatcgtgat gtctttgctg
     2461 gcaggtccaa tgaaggctat aaatgaagga atgatgagct ttttagctgg atttgaatat
     2521 tcgaatccac ttgttcttgg cgtgattgtt ggctgtatgt gtgcgtttga tatgggagga
     2581 ccggttaata aggcggcata tgtaacagga acagctcttt tgacacaagg aaacacgact
     2641 tttatggctg gtgcgtcagc agcttgcatt gcaccaccgt tgattactgg ttttgctact
     2701 ttattgtttg gtaaatattt tgatactaat gatcgtaatg caggtttggt taattttatt
     2761 ttaggatcaa ctcatattac ggaaggagct attccgtttg ctgcgaaaga cccgatccga
     2821 gtattaccaa cgatgatgtt aggctcatca attgctgctg tcttgaccta tctgtttggt
     2881 gtccaagtac cagccccaca tggcggtttt ttagtgttac ctgtagtgac gggaaaaatc
     2941 caatgggtta cagcgattct tattggttcg atcgttggtg gagtgatact aggtttgatc
     3001 caaaagaaaa gagtaactga taaagacaag aagagggata ataaagcaac aaatcgtaca
     3061 gttatcgaag aaggaagagc aggaggttta tcatgacaat cattcatgaa gagaacattt
     3121 ttttacaaca gccattagat aatcaagaag aagcatttaa gtttttagca aagcaaacat
     3181 tctgtttagg aatcgctcat gacgaaaaag aagtatatca aaaacttctg gaaagagaaa
     3241 aagaaggtac tacaggaata atgtcaggtt ttgctatccc tcatgcgaag tctcaaacaa
     3301 tcaatgaacc tagtttgatt atcgtcacac tgaaaaaagg aattgaatgg aacagtttag
     3361 atagacagtc agttgatttt atttttgcgt tatttatccc agattcagaa gcaggaacga
     3421 ctcatttgaa attattgtct ctcgttgcac gatcattgat gcgaaaagag gttacagaac
     3481 agttgagagc tgcaaaatca aaaatagaaa tagctacaat attaactaaa gaaataggtg
     3541 aagatatatg aagaaaatga gtatagaaaa acaggaacgt ttgaagcgat tgacggatga
     3601 agctggaatt attagcgcgc tagctatcga ccaacgtggt gctttgaaga aaatgatcaa
     3661 ccaatataaa gaagctacat cagaagatat catccaattt aaacagatgg tttctcagta
     3721 cctgactccg tatgcttccg ctattttact cgatccagaa tatggtctgc ctgcagcagc
     3781 gcttcgagag aaagaatgtg gtttgttgct agcttatgaa aaaaccggct atgatgcgaa
     3841 aatgccaggc cgactaccag atttactgaa tagttggtca gtgaaaaggt taaaagaagt
     3901 gggtgcggat gcttgtaaat ttttattgta ctatgacgtt gatgaaccag tagagattaa
     3961 tgtgcaaaaa caaatagtta tagaacggat tggttcagaa tgcgaagcag aaggcatacc
     4021 tttcttttta gagctccttt cttacgatgc aactattggc gatccgtctt ctcttgacta
     4081 tgcaaaagta aaaccgcata aagtgattga agccatgcga gaattttcaa aagaacgtta
     4141 tcaagtggat gtattgaaag tagaagtacc agtgaatatg agatttgtgg aaggatatgg
     4201 gcaagatact tgttatagtc aagcagaggc atccgcgtat ttctatgaac aatcgaaagt
     4261 gactgaacaa ccgtttattt ttttaagtgc gggagtcagc gctgcactat ttcaagatac
     4321 attgcgtttt gcaaaacaat caggttcgac attcaatggt gtcttatgtg ggcgagcaac
     4381 atgggcgaag ggagtagcac cttttgttac cgaaggcgaa gaaaaagcga gtagttggat
     4441 gttagaagaa ggaaaacaaa atattaaaga attaagtaca ctattagaag aaacagcaac
     4501 ttctatttat gttaacaagt aagagaaagg attgtctgag tgacagattc aaaaaataat
     4561 tagttattta aaaaaatgtt tgtcaaattt tatagaaaaa aagtataaaa ctgcaaaagt
     4621 tatctaaaac taataataac atttgtcatt aataagctat ttttagttgt tgtaaatgat
     4681 attggaagta ataaaacgat agttgtagga atatcatagg gattaatgtg gatcacgctg
     4741 ctcgataagt tagaccattt tgacggatcg cttatgtggt tcgtcttttt ttctgttctt
     4801 ttattggtaa ctggtatttt tgaggtatct ttgtctattc aagatataaa gctttaaaga
     4861 gctgttataa tagctttttt ggtctaaaaa acctttgaca aatgattaat aattcactat
     4921 tcttgtgttg tggttataac cagtaaagaa gaggtgattt ttatggagag ctcaaataaa
     4981 ggaaaatcat tgtattatca actagttgat ttattgaagg atcgtatcga aacacagatg
     5041 actccgcatg ataagctgtt atctgaaaga gaactttgtc aacactatgg ggtgagtcgt
     5101 accaccgtac gtctggcttt acaggaattg gaaaatcaag gttatattta ccgaagacat
     5161 ggaaaaggta cctatgtctc tgatttgtct gataagtcat cgaacttagc tggagcatat
     5221 agctttacag aagaaatgcg cgaaataggg cgcgtcccta agacggtcat tttagaattt
     5281 agacaaatgg aagctaataa gagaattgct aagaatttga acatccattt aggtgaaact
     5341 gtatttaaac ttaaaagatt gcgtttggca gatgaagagc cattgatggt tgagcgttct
     5401 tatctaccgg cgaaactatt tatgggactt gatttgccgt tacttgaaag taaaccgttg
     5461 tatgatgtgt tttcacagga ttatgaacaa caagttcaat tagctgatga agagttttat
     5521 gcaagtatcg tgcaaaaaaa agatgctgtt gtgctacgaa tcgctgatgg cgctcccgtc
     5581 ttacatctga cgaggataac ctataacgtg aaaaatgaga ttatcgaata tacagatagt
     5641 gtagcaagag cggaccagtt tcattataaa attcggcata tccgaaaatg attgagaggg
     5701 agaacaacat gtttgagcta tcgaagaaca aattaaaaca aataggtgca gcaatcacga
     5761 cacaagaaat aaaacaacaa ccagatctct ggaaagaaac aatcgataga ttgatgcaaa
     5821 gccaagaaaa tttagctcta ttttttgatc aaataaaaaa agaagcaaac ggaagaagaa
     5881 tacgtgttat ttttacgggt gcaggaacgt ctcaatatat tggggatacg ctcttaccct
     5941 atctaaatga acatggagac aatcagtttt ttatcttcca cagttttggc acgacagata
     6001 ttgtagcttc accaaaagaa tttttgtttc caaatgaacc gactttatta gtttcatttg
     6061 ctcgcagtgg caacagtcca gaaagtgtag cggctgtgca aattgcaaat gaacaagttg
     6121 aaacattgtt tcatttgacg attacttgtg ctaaagaggg gatgttggca aaaaacgcac
     6181 aggatgataa acagaattat ctgttattga tgccagagag agcaaacgat gcaggttttg
     6241 ctatgacagg aagttttacg tgtatgttat tgagtgcttt atggatcttt gatcaaacag
     6301 caatggagaa aaaagaaaga tatcttgaac aattagttaa aatcggtcaa gatcttcttt
     6361 caagagatca agaaattcaa aagttattac ctgatttttt tgaacggatc gcttatctgg
     6421 gttcaggaag tttggcaggt gcgacaagag aagcacaatt aaaaatttta gaattaacag
     6481 caggtaaagt tgctacaatt tttgattctt cgatggggtt tcgtcatgga ccaaagtctt
     6541 ttttaaatag cgagacactc gttgtaggtt ttgtgagcaa tcaaccatat acgcgaaatt
     6601 atgacttaga tattttagag gaaataaaag aagatcgggt cactgccaat gtcattgcga
     6661 ttgcgcaacc gggtactatt gatttctcag gtatgactgt gctattggaa gactcggtga
     6721 gtaaattgcc cgatgcctat cttgcattag cgatgattat gactgcacaa atcattgcac
     6781 tctatacttc aatcaaagta gctaataaac cagatacacc atctccaaca ggcacggtca
     6841 atcgagtagt caagggcgtc attattcata agtatgaaac cgaaggagaa atgacagatg
     6901 aatgaagaaa aaaatagggc aatggagaga ctatcaacaa aagatgggat tattagtgca
     6961 ttagcgatcg atcagcgtgg tgctctaaaa aaaatgatca aatcgttggg aaaagagcca
     7021 agtgaagacc aaatcagtga attcaaagaa ctagtatcag ctgagctgac accctatgct
     7081 tctgctattt tattggatcc ggaatatgga ttgccagcag caaaagtcag agcaaaagag
     7141 acggggttat tgttagctta tgagaaaacc ggctatgacg caactacgcc tggtcgtcta
     7201 cctgatttat tagcggattg gtcttctctc agattgaaag aacagcaagc ggatgcagta
     7261 aaattcttac tttactacga tgttgatgaa gcacccgaaa tcaatcattt gaagcatgtg
     7321 ttcatcgaac gtttaggtag tgagtgcgaa ggagaaaatc gtcccttcta tttggagtta
     7381 gtttcttatg acgcacaaat aagcgatagt tcttctccag agtatgcgaa agtcaagccc
     7441 cacaaagtta ttgagatgat gaaagaattt tctgatccaa aatataaagt tgatgtgttg
     7501 aaagtagaag taccagtcaa tatgaattat gtgaatggct attccacagg tgaatttatt
     7561 cacagcaaag aagaggctgc tgccttcttt aaggagcaaa gtgaagcgac tccattacca
     7621 ttcatttttt tgagtggggg tgtttcaaca gaattatttc aacaaacact gatttttgct
     7681 catgaatcgg gttccacctt caatggtgta ttgtgtggac gtgcgacatg gaaagatggg
     7741 gtcaaagcat acgtcgaaaa tggaaaagac ggagctattc attggttaag aacaaatggg
     7801 agagaaaaca tcgagacttt aaataaagta ataaatgaaa ccgctacccc ttggttcaat
     7861 aaaacaaaaa gcaaaaaggt gaagatgaaa tgattacgac agttaccttg aatccttcca
     7921 tcgatatcgc gtatacaatt gaagaattaa acctcgacaa agtcaatcga gttgaaacag
     7981 tcaataaaac agcgggagga aaaggagtga atgtggcgag ggttctaaat ttattaggag
     8041 aagaggtgat agctactggt ttaataggtg gccagcacgg tgaatatcta aagaaccagc
     8101 tagatcagtt agggatcatg catcagtttg ttccaattaa aggagagaca agggattcta
     8161 ttgctatcct gcatagttcg agacaaacag agcttttgga acgaggcccc ttcataacaa
     8221 agaaagaaca acagacattt accgatcatt tcgagcagct cctcgaaata tcagatatta
     8281 tgacgatctc aggtagttta ccccaaggat gccctcttga ttactataag caattggttg
     8341 ctttagctga taaaaaaggg aaagacatat tactagatac ttctggtaaa tttttgcttg
     8401 aagtattgga aggtaaggag aagccactac ttatcaagcc caatctggaa gaattaggag
     8461 aactgattgg ccaacgtatc tgttcttcga ttcaattaga aaaaattcag tccttattag
     8521 ctcatccaat atttgaagga gtgccatggg ttgttgtttc tttaggagag agaggtgctg
     8581 tggcaaaagt tgctcagtgt ttttacgaag tcattattcc taaaatatca gttgttaatc
     8641 ctgttggttc aggtgacgcg acccttgcag gatcggccca tgcgttatca aaaaggcaat
     8701 caatcgaaga gattctcgca ttttctatgg cttgtggtat ggcaaacgcg caacaagaga
     8761 aaactggctg gatcgaccct atgaaagtta cgatgttgat gaaacacatt caagttaaga
     8821 aaatcaaatg aacttaaata taaaagaaag cgttttcttt agttgggaag gaatttgttc
     8881 ttagcttaaa aatgaaatat aagaaagaaa aaatgaaaac gttatctttg aaacagaagg
     8941 gatatttgat gatgtcacag ttttaattga acaataaata gaaaaaatag ataaggagaa
     9001 tgcatgatgg caattattgg tgtaagaatc gatggacgtt tgatacatgg ataagtagca
     9061 aatctttgga caacgaaact gaatattagt cgaatcatgg tcgtggatga tgaggtagcc
     9121 acaaacacaa ttgaaaaaag tggattgaag ttagcgactc cagcaggggt aaaattaagc
     9181 attttgccaa tcgaaaaagc agcaacaaat attttagctg gcaaatatga ctctcaacga
     9241 gtattgatcg tagcaaaaaa gccagatcga atcttatctt tagtagaaaa aggagttcct
     9301 atcaaagaag taaatgtggg gaatatgtca caaacgaatg aaacacggtc cattacaaaa
     9361 tcaatcaatg tggtagatgc agatatcgaa gtatttaaaa aattagatca gcttggtata
     9421 catttaattg ctcaaatggt accaaacgat aaagcagaag actttatgaa tcttttaatc
     9481 aaataggagg aatgatccat ggatattcaa tggtggcaga tcttattatt aacattatat
     9541 gcaggttatc aaattttaga tgaattacag atctattctt caatgagtgc gccagtgttt
     9601 gcagggttat atgcaggttt agtaatgggt gatttaaacg caggtttgat tattggtggc
     9661 agtatgcagt tgacagtttt aggagtgggg acgtttggag gcgcatcaaa aatagatgcc
     9721 aactctggga cgattttagc aactgccttc tcgatttctc ttggaatgaa tccagaacaa
     9781 gcgattgctg ctattgcagt gcctgtagca agcttaatga tccaattgga tattttagct
     9841 agattcgcta acacatactt tgcccatcgt attgaccgtc acgtagaaga catgaattat
     9901 caagcaatcg aacgcaattt cttaatggga gctttacctt ggtcgctctc tcgtatgatt
     9961 cctgtatttt tagctttagc atttggtggt ggattagttg aaaatgttgt ttctgtttta
    10021 aacgggaatc taaaatggct aggcgatgga ctttcagtag caggagctgt tttaccagct
    10081 gttgggtttg ccattcttct gcgctattta ccagtaaaaa aacatctatc ttatcttatt
    10141 ttaggattta cgatcacggc attattagca acgttattct ctaatgttca attattagga
    10201 acaagtgtgg caagcgttgt taaagatctt ccggcaactt tcaattcgct gccgatgctt
    10261 gctgtagcat tgattggtct agcactagca atgatcagtt ataagaatga tcaaaacaaa
    10321 gaccatcaac cattagctag tgagccatca cattctgttg agggggaaat cgaagatgac
    10381 gaaatctaat tacaaattaa caaaagaaga ttttaagcaa atcaatcgaa gaagtttgtt
    10441 cacttttcaa ttaggttgga actatgagag aatgcagggt tctggctatt tatatactat
    10501 cttgccacaa ctaagaaaaa tatatggaga caatacacca gaattaaaag agatgatgaa
    10561 aacacatacg caatttttta atacttctaa tttttttaat acaatcatta ctgggattga
    10621 tcttgcaatg gaagaaaaag agggaattgc ttcaaaggaa accgtatcgg ggctgaaagc
    10681 tggattgatg ggttcctttg cagcgattgg agattccgta tttgctgctt tgattccaac
    10741 gatttttggg gctttggcgg cgaatatggc aactgatgga aatccgatag gtgtgtttat
    10801 atggattttt gctcagatcg ttgtcatggt ttttcgttgg aagcaacttg aatttgcata
    10861 caaagaagga atttccttag ttactactat gcaatctcgc ttaactgcat taacggacgc
    10921 agccacttta ttaggggtat tcatggtagg ggcattagtt gcgacaatga tcaatgttaa
    10981 attttcatgg gcaccaacga ttggcgatgt gacattgaat atgcaaaact atatcgatat
    11041 gatcttacct aaaattttac ctgctgggat cgtcggtggt gtttattggt tattaggaaa
    11101 gaaaaacatg actcctactc gagcgatttt tatcgtatta attgtgtgtg ttgctttatc
    11161 tgcattgggt gtgatttcga aataagggag agcgaaaaat gagtagacaa ttggtattga
    11221 ttagtcacgg aaaattttgt gaggaattga aaaaaagtac agaaatgatc atggggcctc
    11281 aagaggatat ctacacgtta cctttattac cagaagatgg cactgaaaca tacaaacaaa
    11341 agtttctcac tgtcacagat tcgttaaatg attttgtggt actatgcgat cttttaggtg
    11401 gtacacctgc aaatatcatt tctaaactaa taatggaagg acaacagatt actctttatg
    11461 ctgggatgaa tcttccgatg gtcattgaat ttatcaactc acaaatgatt ggttcagagc
    11521 ccgagtttgt tcgtgcagga tgtgaaagca ttgtctctgt caacgaatta attaatggaa
    11581 tagcagaaga ggaagagtaa caaaaaagat gagggcttag ctctcatctt ttttgtccta
    11641 tgtttttatt tccgcttctg ctgctttcct gcgttgcggc ctttgttgtt tgtactgttt
    11701 tttggttgtt tgatttgttt tgttgcttgt ttgttgttag ctggctttgc tgattctgtc
    11761 acgtcttttc ttggagtgac gacttgtttt ggcgggtttt gtttcaactc ttctgccact
    11821 tgtgctttca aacgtggttt catcataacg tttgtgatga atgtttgcag acagctgaac
    11881 acaccaccga ctacccagta aagtgtaaca ccggctggcg cactgatcga catgaagacg
    11941 atcatagcag gagagacgat tagcatcgta cgcatcgtct ttttctgttc ttcaggaata
    12001 ccgatcgttg agatgtatcc ttgaagcaga taggcgaccc ctgcaatgac aacaagtacc
    12061 atacttggtg agcctaaatc gatgccgtag aaagatgatt cccgaatacc ttctgtataa
    12121 cgtgccgtaa agtacaaggc agagaagatc ggcatttgga tcaatagagg cagacagccg
    12181 attccgccgg tcatactcaa tccgttttcg cggtatactt gctgcatttc tgcttgtgct
    12241 gccatttgtt cttcacgtgt tgttgcagct ttcaattttt gttgggctgc ttcaacttgt
    12301 ggttttaacg cttgcatttt ttcagattgg atcattgttt ttttcgattg actaatacct
    12361 agtggcaaga tgatgatacg gacgatcaca gtcattgcaa taactgccca gccataagac
    12421 caattgaaat tctcaactag atatgtaatc gcttggccca taggatggac gagtactcga
    12481 taaacgattc ccgaagtgtc agggtttccg tttgaatcca tccgcacaca gccagataaa
    12541 aagagcagga tactgacaag tccggatccc aataaccagt ttttccattt attcatagaa
    12601 tacttcctct tctataattt ttacacaaac ttaactatac taaaaaagcg catggaattc
    12661 aatcaacttc atagaaattt catataaata ttcgttcttt tacgtagcga a
//
LOCUS       DAMEEU010000080        12494 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.081, whole genome shotgun sequence.
ACCESSION   DAMEEU010000080 DAMEEU010000000
VERSION     DAMEEU010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12494)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12494)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12494
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.081"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            158..730
                     /locus_tag="PB779_002339"
     CDS             158..730
                     /locus_tag="PB779_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003706982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HDE0739845.1"
                     /translation="MTENKATQERTPQERLQEEQEHKEHVHHTKINAAAIADHLLGNM
                     HTLHVKLHQYHWYVKGANFFTLHEKFEELYNENEKWFDKLAERLITSGHKPASTTVEF
                     EKYSMLSEDAVNKYAKAEDMVENIIEDFRSTRDLTIRAIRLAQDEGDDALEDTLIAFK
                     NDLDKNIWMLQAFIGKEALEDDDALDEDED"
     gene            875..1579
                     /locus_tag="PB779_002340"
     CDS             875..1579
                     /locus_tag="PB779_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011476586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDE0739846.1"
                     /translation="MTKHTHHEIGDHAACIRLVPIFNHLEDSAMNYIAEKAHTKQYQK
                     GEFLFRSQEKEDTLYIINRGKIRIYRLADSGKEQLVRILNPGDFTGEWTLFNPDAVHE
                     EYAEATRDTVVCMIQQKDVQDFLEQYPAISLKLLAEMSKRLESSERQTTQVAVESVIT
                     RLVLFLAENVEPEMGNSPTITLPMAKKDIASYLGTTPETISRKFGELEDEGLIQQLSG
                     KRIKIQDLDDLLLYSE"
     gene            1807..2145
                     /locus_tag="PB779_002341"
     CDS             1807..2145
                     /locus_tag="PB779_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739847.1"
                     /translation="MHCFWVIVAITLSAAGAFFVVPFTKNTIGGEAKTSNVVEADRLA
                     MEKEEEVVKGAGVIGHGKVAYYEASDQGDKSVFTVWFPWSLAGILFSITMTRMTRKIE
                     EMEQIEWDSY"
     gene            2130..2984
                     /locus_tag="PB779_002342"
     CDS             2130..2984
                     /locus_tag="PB779_002342"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HDE0739848.1"
                     /translation="MGFVLGVLNPHVVEIGSVVIHWYGVIIAAGILAALQLSTKEAKK
                     KGLEEDTIIDMALWAIPIGLLGARLYYVLFELGYYLQNPGQILAIWNGGIAIYGGLIA
                     GGGTLYWYAKKKGTSLALVLDILAPNVLLAQSIGRWGNFMNQEAHGGPVTRQFLENLY
                     LPEFIIEQMNMNGTYYHPTFLYESLWSLLGFVLIVTIRNRKQLLRQGEVALSYVLWYS
                     VGRFFIEGMRTDSLWIGEWIRVSQALSLALFIGAIVVWFIRRQDYPPISYYSDGNKGQ
                     KKTIKMVN"
     gene            3131..3364
                     /locus_tag="PB779_002343"
     CDS             3131..3364
                     /locus_tag="PB779_002343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy-metal-associated domain-containing
                     protein"
                     /protein_id="HDE0739849.1"
                     /translation="MEKAILQLETLSCPSCMQKIEGAVKSVNGIDKDSIKVLFNSSKV
                     KTNFDSAVTSIEEIQKAIENVGYPVLKAKVKAV"
     gene            3562..5466
                     /locus_tag="PB779_002344"
     CDS             3562..5466
                     /locus_tag="PB779_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDE0739850.1"
                     /translation="MQQYILSKKNVITVISGLLIVLGFFSHFVLENVGLSEWSLIIAS
                     VFGITPIAIQAFQAMKVKVISIDVLVSIAAIGALFIQNYEESAIVTFLFLFGHYLEQR
                     TLNQTRSAIKELTEMAPESALKQMDNGEFEEVEVDDIDEGDILLVKTGAKVPVDGIVL
                     TGEGHINEASITGEAIPVNKLADAEVFAGTILENGTIQIRADRVGEDTTFGKIIELVE
                     EAQDSKSEAERFIDRFSKYYTPAVLVLAIVVWAFSQNIELAITILVLGCPGALVIGVP
                     VSNVAGIGNGARNGVLLKGSEVIQDFSNVDTIVFDKTGTLTVGNPTVAATELYEKDPA
                     ETLGYLASVERESDHPLAKAVLNQIGETNFYPVEGTEVVKGGGIVSSVAGHRVAVGNV
                     ALMEKENVTLSKKVQKDVKRFEQQGNSLVLTAVDGELKVLMGIRDQVRPGVKANLQEL
                     KDLGVKNLVVLSGDNQGTVDVVAGELGLTEAHGYMLPEDKSAYIGKLQQRGQIVAFVG
                     DGVNDSPSLALADIGIAMGSGTDVAIETSDVVLMNSNFSNLPHALGLVKATANNMKQN
                     IVISIGVVLVLLTSVFFSEWMNMSIGMLVHEGSILVVIFNGMRLMKYKLKGRKEQKEV
                     SAPAEKVKIS"
     gene            5776..6138
                     /locus_tag="PB779_002345"
     CDS             5776..6138
                     /locus_tag="PB779_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0739851.1"
                     /translation="MEKVCQVTIVHKEKVNVIKKKLDQKDFSNLLVLGKCFSDSSRIK
                     IFYALETYKEMCVCDLAEILTASVATTSHHLRFLKKHGMAKSRQDGKVVYYSLANEDI
                     LSAIRVFLKLSENLSMKS"
     gene            6155..6766
                     /locus_tag="PB779_002346"
     CDS             6155..6766
                     /locus_tag="PB779_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HDE0739852.1"
                     /translation="MLQSIFSAIAVYISTSIDYLFILLIIFSQSHTKKGIRHIFWGQY
                     LGTGILVAVSLFAAYVLNFIPQDWIIGLLGLIPIFLGIRVAFVGEEEEEEEEVVEKLE
                     SRGTNRLFWTVALITIASGGDNLGIYIPYFTSLAFSEIIIALIVFAISVAVLCYISYK
                     LAKISFVSETLEKYERIIVPIMFIALGIFIMIENGTIQTLLGF"
     gene            complement(6868..7776)
                     /locus_tag="PB779_002347"
     CDS             complement(6868..7776)
                     /locus_tag="PB779_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HDE0739853.1"
                     /translation="MSKSDKDHNHSNQNQPKKNIKIAFFINLIFSISEFFFGFLFNSV
                     SIMSDAVHDLGDSISIGFAWFFQGYSEKKQDERFTFGYNRFSLLGALITGVVLISGSF
                     FMIYRSVPRLIDPQPVNYSGMFWLSLVAIALNGYAAWILSKGTSKNESMLNLHMLEDV
                     LGWIGVLIVSILMNFTEAYRLDPILSILIALYILYKTVPEFFTTMKILLNGSPENVNV
                     KSLADSIKNVPAVKDLSHFHIWSLDGEENALIITVLIDPSDIDKAREIKEEIAEVAHK
                     SSVENHITIEITTSKEELEKGYSHNT"
     gene            complement(7818..8132)
                     /locus_tag="PB779_002348"
     CDS             complement(7818..8132)
                     /locus_tag="PB779_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HDE0739854.1"
                     /translation="MDIKTTSPIDKGSILSISKLFKVISDPTRLSVLFLLQKKECSVG
                     NIAISLDMEQSAISHQLKTLKDARLVKSRREGKSMLYSLDDLHVFSILEQVLTHVNEL
                     EK"
     gene            8431..10362
                     /locus_tag="PB779_002349"
     CDS             8431..10362
                     /locus_tag="PB779_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDE0739855.1"
                     /translation="METIQEQQSQEKHNHNHNHDHDHDHGKMPVVLYFVGLALAVIAL
                     FLNEDYQLVQNVLFSIATISAGYHVILLEGLGETIENSKAQKKFIPNSHILMGLAAIG
                     ASLMGNFWEGTLLILIFSGAHFLEDYAEGRSKREITKLLEMNPTTARLILPDGSTKNV
                     DVSELKVGDQLQVLNGDQVPIDGVILSGSTSIDESSITGESIPKEKSKGDGVFGSTIN
                     GTGTFTMKVTKENKDTVFSKILQLVNQNQDNQTKAASIIQKFEPKYVTVVLIAIPLFM
                     LLAPFLLDWTWSQSVYRGLVLLVAASPCALAAATVSATLSTTSNLAKKGVLSKGSSYL
                     SQLADIKAIAFDKTGTLTKGKPEVTNYYFADSVNEENMIDIVVALEKESNHPLADAIL
                     RKFEQKNKLTIEVENQIGKGLTGDYKGRNYRIGKPTSFDDVSDEYSRLNNEWASEGKT
                     VVYVAVDEEVIGLIALMDVPSEYAKETIEYFRKQGIHTTLITGDSEMTGKAVAKQLGI
                     DEVIANVMPEDKSRIIDEQKEKYGVTAMVGDGVNDAPALVNADVGIAMGDGTDVAVEV
                     SDLVLMQNNLSKLVQSHNISSKMNRVIWQNIIFSMAVVAFLIVVSFLGLTDIAISVII
                     HEGSTLVVILNGLRLLKAV"
     gene            10655..11206
                     /locus_tag="PB779_002350"
     CDS             10655..11206
                     /locus_tag="PB779_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0739856.1"
                     /translation="MGYNVQPLRSQQEINDFLFCLRRNKNAERDVFLFLIGINSGLRM
                     SDIVKLKKKDVITSKNPRIVEQKTGKTRILYLSSLQDLIHGYTAPLDPEAYLFPSTKG
                     GHLEVNTVYQMFQKVAKLLGRDDIGTHTLRKTFGYHYYKKTKDVATLMEIFGHSSEKI
                     TKRYIGINEDEISETLLNFRLGF"
     gene            11519..12061
                     /locus_tag="PB779_002351"
     CDS             11519..12061
                     /locus_tag="PB779_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739857.1"
                     /translation="MSIKETTQITRQLNAIYKAAHLLQEHFVDKKVSFVGEVSTVAII
                     FSTTNFMHLCGIDYRRGTHLFFQDALDRKINLQDIQIKTDGTTFQKLQVIGSLDLLLG
                     KHISIVGRGVYSSLRYDAAIRTRKKILALSLKQNGLIYIPISLLNLSSKEIGPGQKVT
                     GIFSEDLTSGELKMIMEVID"
BASE COUNT         4048 a         2093 c         2609 g         3744 t
ORIGIN      
        1 aatttaatag agaagcctgg cgtctattaa gaaataattt tcttgatgag cgtcaatttt
       61 tttaacggaa atctatccta tactaaattc agtaaagaaa aaggaggaat caaagaaagc
      121 tattttaaac aaaccaaaat tataggagga ataaatcatg actgaaaata aagctactca
      181 agaaagaaca ccccaagaaa gattgcaaga agaacaagaa cacaaggaac atgttcatca
      241 tacgaaaatt aatgcagcgg ccattgcgga tcatctttta ggcaacatgc atacattaca
      301 tgtgaaactg caccaatatc actggtatgt aaaaggagcc aatttcttta cgttgcatga
      361 aaaatttgaa gagttgtata acgaaaatga aaaatggttc gacaaacttg cggagcgtct
      421 aattacttct gggcataaac ctgcttcgac aacggttgaa tttgaaaaat attcgatgct
      481 ttcggaagat gcagttaata aatacgctaa agcagaagac atggttgaaa atattatcga
      541 ggacttcaga agcactcgtg acctaactat tcgcgcgatt cgtttagctc aagacgaggg
      601 tgacgatgct ttagaagata cattgattgc ttttaaaaat gacttagaca agaacatttg
      661 gatgctgcaa gcgttcattg gtaaagaagc attagaagat gatgacgctc ttgatgagga
      721 tgaagattaa ggtaaaagta gaagctgatt tagggattgg aattctttcc agtccttttt
      781 ccattttctt gatgtgcatc aatttttttg tagtaagaga cttatataat aaaagcagcg
      841 aatataaaca aaataaataa agggggagaa tgaattgact aaacataccc atcatgaaat
      901 tggcgaccac gcagcctgta tccgcttggt tccaatattc aatcacttag aggatagcgc
      961 gatgaattac attgctgaaa aagcccacac gaaacagtat caaaaaggag agtttctgtt
     1021 tcgttcacaa gaaaaagagg atactttata tattatcaat cgtgggaaaa tccgtattta
     1081 tcgattggca gactctggca aagagcagct agtgcggatc ttgaaccctg gtgatttcac
     1141 cggagaatgg accttgttca acccggatgc agtacacgag gaatatgccg aagcaacccg
     1201 agataccgtt gtctgtatga ttcagcaaaa agatgtccaa gattttctgg aacaataccc
     1261 agctatttct ttaaaactat tggcggaaat gtctaaacgg ttagaaagtt cagaacgtca
     1321 aacgacacaa gtagccgtgg agagtgtcat tacccgttta gttttgtttt tggcagaaaa
     1381 tgtggaacct gaaatgggca actctcccac catcaccctg ccgatggcaa aaaaggacat
     1441 tgcttcctat ttaggaacga cacctgagac catcagtcgc aaatttggag aattggagga
     1501 cgaaggattg attcaacagc tgtctgggaa aaggatcaag attcaggatt tagatgattt
     1561 attgctttac agcgaataat cggacacact tttttctaca cgttggtgtt ctgtcgctct
     1621 tcattaacaa cgggacagaa ctcagtgctt ttgcttccat ctgtccgttt ttggcttttt
     1681 taagacagaa cgaccttcat tcattggaaa aataaaagca caaacatgat aaccctcaag
     1741 tttttttgtt ttatttttct ttaagatagg gttgtcgaac aaaacgtaaa aataagtagg
     1801 gtgaatgtgc attgtttttg ggtgatagtt gccatcacgt tgtcagcagc gggggcattc
     1861 tttgtcgtcc ctttcaccaa gaacacgatt ggcggcgaag caaaaacgtc taacgttgtt
     1921 gaggcagata ggttagctat ggaaaaagaa gaggaagttg taaaaggagc cggcgtaatc
     1981 ggacacggaa aagtggcgta ttacgaagcg agtgaccagg gagataaaag tgtattcact
     2041 gtttggtttc catggagctt agccggaatc ttgttcagca tcaccatgac tagaatgacg
     2101 cgaaaaattg aagaaatgga gcaaatagaa tgggattcgt attaggcgtt ttgaatcccc
     2161 atgtggtgga gattggttct gttgtgattc attggtatgg agtcattatt gcagcgggca
     2221 tattagcggc tctccagttg agcaccaagg aagcaaagaa aaaaggactg gaagaggata
     2281 ccattatcga tatggcctta tgggcaattc cgattggact cctcggcgct cggctttatt
     2341 atgtgttatt tgaacttggt tattatctgc aaaatccagg acaaatcctt gcgatttgga
     2401 atggcggcat tgcgatttat gggggattga ttgcaggagg gggtacgcta tattggtatg
     2461 caaagaaaaa aggtacttct ttggcactcg ttcttgatat tttagcgccc aatgtattgt
     2521 tagcccagtc cattggtcgt tggggcaatt ttatgaatca ggaagctcat ggtgggccgg
     2581 ttactcgtca attcttggaa aatctttatt tacctgaatt tatcattgaa caaatgaata
     2641 tgaatggtac ctactaccat ccgacttttt tatacgagtc attgtggagt ttgttgggct
     2701 ttgtcctcat cgtcactata cggaaccgaa aacagctttt gcgtcaagga gaagtcgctt
     2761 tgagttacgt tttgtggtac tcagtgggtc ggttcttcat tgaaggtatg cgaacggaca
     2821 gtttatggat tggcgagtgg atccgcgttt cgcaagcctt gtctctggcc ctgtttattg
     2881 gcgcgattgt agtatggttt atacgcagac aagattatcc accaatttct tattattctg
     2941 atggcaataa ggggcagaaa aagactatta agatggtgaa ttgagcaaaa agataaaaag
     3001 aagtgcaaaa cttgatatgc gtcaattttc gtttgctaaa agtgagctat actacagttg
     3061 taaagaggaa aaggcagtgt tcattaatct gctgccgata aaataaaaac acataaagga
     3121 gataggaatt atggaaaaag ctatattgca attagaaacg ttgtcttgtc caagttgtat
     3181 gcaaaaaatt gaaggtgccg tgaaatcagt taacggtatt gataaagaca gcattaaagt
     3241 attattcaac tccagcaaag tcaaaaccaa ttttgattca gctgtcactt cgattgaaga
     3301 gattcaaaaa gctatcgaaa acgtaggcta tccggttctt aaagcaaaag tcaaggccgt
     3361 ttaacagatt aaatgaacta ggcaattctg gaagaaaagc tatttttcca ggattgcttt
     3421 ttttgttgca atccgattcg aggtgcttag aaacgataaa agagaacttt ctaaacttga
     3481 tgtcagtcaa ttaattactt aggcaattat cttatactgt gtttatcaat aaaagagaaa
     3541 ttaaatttgg agggaaaaag catgcaacaa tatatattaa gcaagaaaaa tgttatcacc
     3601 gtcatcagtg gattgttaat cgtactcggt ttcttcagtc actttgtttt agaaaacgta
     3661 ggactttcag agtggtcttt gatcatcgcc tctgtctttg ggattacgcc aattgccatt
     3721 caagcgtttc aagcaatgaa agtcaaagtc atcagtattg atgtcttagt cagtattgca
     3781 gcgattggtg cgctttttat tcaaaattat gaagaatcgg ctattgtcac gttcttattc
     3841 ttattcggac actacttgga acaacgaaca ttgaaccaaa cgcgatctgc tatcaaagaa
     3901 ttgactgaaa tggcacccga aagcgccttg aaacaaatgg ataatggcga atttgaagaa
     3961 gtagaagtgg atgatataga tgaaggggat atcttgctcg ttaaaacggg tgcgaaagtt
     4021 ccagtagatg gcatagtcct tacgggtgaa gggcatatca atgaagctag cattacaggt
     4081 gaagctattc cggtcaacaa gctagctgat gcagaagttt ttgcaggaac cattttagaa
     4141 aacggaacga ttcaaatcag agctgaccga gttggtgagg acaccacatt tggaaaaatt
     4201 attgaactcg tggaagaagc acaagattct aaatccgaag cggaacggtt cattgatcgc
     4261 ttttctaaat actacacacc agctgtcttg gttctggcaa ttgttgtatg ggcgttcagt
     4321 caaaatattg agttagcaat caccatcttg gttctaggtt gcccaggcgc attagttatc
     4381 ggagtgcctg tctcaaacgt tgccggtatt gggaatggtg ctcgtaacgg tgttctttta
     4441 aaagggagtg aagtcattca agacttcagt aatgtggata caattgtatt tgataagaca
     4501 ggtactttaa ctgtcggaaa cccaaccgtt gcagcgactg aactgtatga aaaagatcct
     4561 gctgaaacgc ttggctatct ggccagtgtg gaacgggaat cagatcatcc attagcaaaa
     4621 gcggtcttaa atcaaattgg agaaacaaac ttttatcctg ttgaaggaac tgaagttgtg
     4681 aaaggcggcg gaatcgtttc aagtgtagct ggacatagag tggctgttgg gaatgtggcc
     4741 ttgatggaaa aagaaaatgt cactctcagc aaaaaagtgc aaaaagatgt caaacggttt
     4801 gaacaacaag ggaactctct cgttttgaca gcggtcgacg gtgaattaaa agtactgatg
     4861 ggcattcgcg atcaagtccg tccgggtgtg aaagctaatt tgcaggaatt aaaagacttg
     4921 ggcgtgaaaa atctagtcgt tctttcagga gataaccaag gaaccgttga tgtggtcgcc
     4981 ggcgaacttg gtttgaccga agctcacggc tacatgttgc cggaagacaa atcggcttat
     5041 atcggaaaac ttcaacaacg tggtcaaatt gtagcctttg ttggagatgg cgttaacgat
     5101 agtccgtcct tagctttagc agacattgga atcgcaatgg gaagcggaac ggacgtagcg
     5161 attgaaacat ccgatgtcgt tttaatgaac tcgaacttca gcaacttgcc tcacgcatta
     5221 ggattagtaa aagccaccgc aaataatatg aaacaaaata tcgtgatttc aattggagta
     5281 gtgttggtct tgttgaccag cgtcttcttc agcgaatgga tgaatatgtc tatcggaatg
     5341 ttggttcatg aaggtagtat cttggtggta attttcaatg gcatgagatt aatgaagtat
     5401 aagttgaaag gtcgaaaaga acaaaaagaa gtatcagcac ctgcagagaa agtaaaaata
     5461 tcttaagaat aaattagaag aggctgagac aatagtccat ccttgaaatg acaaaagcgg
     5521 aaactcagat ttttaaatct gggattttcc gcttttttga gttcttgaaa aaaaataaga
     5581 gtatagagta tgttctttat aaaattaatt ttcgtgtaaa tgattaaaaa atttaataat
     5641 aaaatttaaa ttcctattaa gttgtaacac atgaaattgc ttataatagt gtattgaaat
     5701 taaggtagat tgacaaacga gtgatcaaat agatatacta ccttcaaacg accgtttgaa
     5761 tgtgaggtga gatgaatgga aaaagtttgc caagtgacta tcgtacataa agaaaaagta
     5821 aatgtaataa aaaaaaaatt ggatcaaaaa gatttttcaa acttacttgt gttagggaaa
     5881 tgtttcagcg attcttctag gattaaaatt ttctatgctt tagaaaccta taaggaaatg
     5941 tgtgtctgtg atttagcaga aatacttact gctagtgtcg ctacaacgtc acaccattta
     6001 cgttttttaa aaaaacatgg aatggcaaaa tcacgtcaag atggaaaagt agtttattat
     6061 tctttagcga atgaagacat cctttccgct attcgtgttt ttttaaagtt atcagaaaat
     6121 ctatctatga aatcttagtt tggaggaagt tattttgtta caaagtattt tttcagctat
     6181 cgctgtttat atttctacca gtattgatta tttgtttatc ttgctgatta tcttttctca
     6241 aagccacaca aaaaaaggta ttcgtcacat tttttggggt caatatcttg gaacaggtat
     6301 tttggtagcc gtaagtttgt ttgctgctta tgtgctaaat tttattccgc aagattggat
     6361 cattggtctt ctcggtctaa ttccgatttt cttaggaatc agagtcgctt ttgttggcga
     6421 agaggaggaa gaagaagagg aagtcgttga aaaactcgaa tctagaggaa ctaatcgctt
     6481 attctggaca gttgccttaa taacgattgc ttctggaggc gataatttag gtatttatat
     6541 tccatacttt acctcgttag ctttttcaga aatcattatt gctttaatcg tattcgctat
     6601 ctctgttgcg gttctctgct atatcagtta caaattagcc aagatttctt ttgtttccga
     6661 aacgttagaa aaatacgaac gaatcattgt ccctataatg tttattgcgt taggaatttt
     6721 tattatgata gagaacggga cgatacaaac gctactaggt ttttaaaaat cataatcacg
     6781 aaagataaaa agagaggcag cgactaatca aaatcgctgc cttttttgct tttcaaataa
     6841 tgaagtattt tttagcgtag aactatctta cgtgttgtgg gagtatccct tttcaagctc
     6901 ttctttgctt gtagttattt ctattgtgat atgattctct acgcttgatt tgtgtgcgac
     6961 ttctgcaatt tcttctttta tttccctagc cttgtctatg tctgaagggt ctataagaac
     7021 cgtgatgata agggcgtttt cttccccgtc cagtgaccaa atgtgaaaat gtgagaggtc
     7081 ttttacagca ggaacatttt taatggagtc cgccaagctc tttacgttta cattttcagg
     7141 cgaaccattc aataaaattt tcattgtggt gaaaaattca ggaacggttt tgtagaggat
     7201 ataaagtgca atcaaaatcg ataagatagg atccagacga tatgcctcgg taaagttcat
     7261 tagaatactc acaatcaaga ctccaatcca ccctaatacg tcttccagca tatggaggtt
     7321 caacatgctc tcgtttttgg atgtgccttt gcttaaaatc cacgcagcat atccattcaa
     7381 tgcaatagct acgagagaaa gccagaacat gccactataa tttacgggtt gtgggtcaat
     7441 caaacgtggc acactacgat agatcataaa aaacgagcca ctaattagca caacgccagt
     7501 tatcagcgcg cccagtaaag aaaagcggtt atagccaaaa gtgaaccgtt catcttgttt
     7561 tttctctgaa taaccttgaa aaaaccaagc gaatccaatt gaaatagagt cccctaaatc
     7621 atgaactgcg tcggacataa tggacacact attgaaaaga aagccaaaga aaaattcgct
     7681 tatagagaaa ataagattta tgaagaaagc aattttaata ttctttttcg gttgattctg
     7741 attcgagtga ttatggtctt tatctgattt tgacatttaa aaacctccta agtttgtatg
     7801 ctacatacta attggtttta tttttctaat tcattaacat gagttaagac ttgttcgaga
     7861 atactaaaaa catgaaggtc atctaaactg taaagcatac tttttccttc tcttcttgat
     7921 ttcactaagc gtgcgtcttt caacgttttt aattgatgag aaatagcgga ctgttccatg
     7981 tccagagaaa tagcgatatt tccaacacta cactcttttt tctgtaaaag aaagagaacc
     8041 gacaatcgtg taggatcact aatcacctta aatagtttgc ttattgacag aatagatcct
     8101 ttatcgattg gagaagttgt ttttatatcc atagtgtttt tattcctttc atatgacctt
     8161 ccgttcatat ctatattacc atatgagcga aacaatgcta atcttttgtt tataaaagag
     8221 aagtggcgtt ctctttatct tgacaaaatg tatatagcga tataaaatga gtatacaaac
     8281 atatgattaa ttagtcatat gtaaggtgga ttcattacga tttacttttg gaataaacga
     8341 aaggagtcag aaatagcaga aatttatgtg attcaagaag taaatgatgg aaaacaaagg
     8401 aattataaat tatataggga ggcaatagaa gtggaaacta tccaagaaca acagtctcaa
     8461 gaaaagcata atcataatca caaccacgat cacgaccatg atcatgggaa aatgccagtc
     8521 gttttgtact ttgttggttt agcattagca gtgattgctc tatttttgaa tgaagattat
     8581 cagttggtac aaaatgtttt gttctcaatc gctacaatca gtgccgggta tcacgttatt
     8641 cttcttgaag gccttggaga aacaattgag aattcaaaag cacaaaaaaa gttcatacct
     8701 aattctcata ttttaatggg attagcggca attggagctt ctttgatggg gaatttttgg
     8761 gaaggaacat tattgattct tattttttct ggcgcacatt ttttggaaga ttatgcagaa
     8821 ggaagaagca aacgagaaat aacgaaatta ctcgaaatga atccaacgac tgcccggtta
     8881 atcctgcctg atggtagtac aaaaaatgtg gatgtcagtg aattaaaagt gggagatcaa
     8941 cttcaagtgt tgaatggcga tcaagtacct attgatggcg tcattttgtc tggatctaca
     9001 tccattgatg agtcgtctat tactggagaa agtatcccga aagagaaatc caaaggagat
     9061 ggcgtcttcg ggagtacaat caatggaaca ggtaccttca cgatgaaagt caccaaagaa
     9121 aacaaagata cagtattttc aaaaatttta caattagtga atcagaacca agataaccaa
     9181 acaaaagctg cgagtattat ccaaaaattt gaaccgaaat atgtcacagt tgttttaatt
     9241 gccattcctc tattcatgtt attggctcct tttctacttg attggacatg gtcacaaagt
     9301 gtctatagag gattggtcct tttagttgca gcttcaccgt gtgctttagc agcagctact
     9361 gtctcggcaa cgctatcgac gacttctaat ttagccaaaa aaggagtcct ttcaaaaggt
     9421 agttcttacc tgtctcaatt agccgatatt aaagcaattg catttgataa gacgggcacc
     9481 ttgaccaaag gaaaacctga agtaaccaat tattattttg ctgattccgt gaacgaagaa
     9541 aacatgattg atatcgtagt agctcttgaa aaagaatcca atcacccctt agcagatgct
     9601 attctaagaa agtttgagca aaaaaacaaa ctaactattg aagtagaaaa ccaaattggt
     9661 aaaggattga cgggagatta caaagggaga aattatcgta taggaaaacc gacttcgttt
     9721 gatgatgttt cagatgaata tagtcgttta aataatgaat gggcgtcaga aggtaagaca
     9781 gtcgtatacg tagcagtaga tgaagaggtt ataggcctta ttgcccttat ggacgttccg
     9841 agtgaatatg ctaaagaaac cattgaatat tttaggaaac aaggtataca caccacatta
     9901 attactggtg actcagaaat gacgggaaaa gcggttgcta aacaattagg aatagatgaa
     9961 gtgattgcga atgtcatgcc ggaagacaaa tccagaatta tagacgaaca aaaagaaaaa
    10021 tacggcgtga ccgccatggt tggagacggt gtaaatgatg ctcctgctct tgttaatgca
    10081 gatgtgggaa tcgctatggg agatgggact gatgtggcag tagaggtatc tgatttagtt
    10141 ttaatgcaaa acaatttatc taaattggta caatctcata atatttcttc gaaaatgaac
    10201 cgtgttattt ggcagaatat tattttttca atggccgttg ttgctttttt aattgtcgtt
    10261 agtttcttag gcttaacgga tattgcaatc agtgtcatta ttcatgaagg aagtactttg
    10321 gttgttattt tgaatggact tcgattgcta aaggcagtct aaagaatgat tgcacaactt
    10381 caaattaatc gagtaataga gataattaag gattacacta cattttttat ctctattact
    10441 tgtttatatt tatctagatg ttcaaagtca aaatgatata tcaaccatac tcttgtggcg
    10501 cgggttgaat ataagataca tgaaattgga taaaatcatg tatcaagaat cctatcctta
    10561 tagggttctt tttttttact ccccctaaac acacgatttc gtgttgtaat aactataatc
    10621 atgtattcga acagactaaa aaggagggat tgtcatgggc tataatgttc agccactacg
    10681 gtcgcaacag gagattaatg attttttatt ttgcctgcga cggaataaaa atgcggaacg
    10741 tgacgttttc ttgtttctaa ttggaattaa cagcggtctg cgcatgtccg acatcgttaa
    10801 actcaagaaa aaagacgtga ttacctcaaa aaacccgcgc atcgtggagc aaaagacagg
    10861 gaaaacacgc attttatact taagcagctt acaggacttg attcacggct ataccgcacc
    10921 cttagatccg gaggcttact tgtttcccag tactaagggc ggccatttag aagtcaatac
    10981 ggtctaccag atgtttcaaa aggtcgcgaa gctgttagga agggacgata tcggcaccca
    11041 caccctacga aaaacctttg gttaccacta ttacaagaaa accaaagacg tggccacctt
    11101 aatggaaatc tttggtcaca gcagcgagaa gattaccaaa cgctacatcg gaattaatga
    11161 agatgaaatc agtgaaacgt tattaaattt tcggttaggt ttttgattgt attatataat
    11221 agataagcac agtaagacgg ttataatcac ccacagtatt ggacaaatca accttttttt
    11281 ggtatattat atatacaaat gagagcaggc tcatagtcaa cttgatataa atccggaaca
    11341 taagggtccg gcgggtggcg agcaccaaaa ctaaactcga tacaaatccg gaacgtaagg
    11401 gtccggcggg tggcaagcac caaaactaaa cctgtacaaa aggctgctct tttgagcagc
    11461 tttttttatt gggaaaaagg agcattcttc gcacgcggca aaaaaagaat acaaacgcat
    11521 gtctataaaa gagacaaccc aaattaccag acagttaaac gcgatttata aggctgctca
    11581 tctcttacaa gaacattttg tagataaaaa agtatccttt gtcggagaag tctcaacggt
    11641 agcgattatt ttttcgacaa ctaattttat gcacctctgt ggcattgatt atcgcagagg
    11701 cacacacttg ttttttcaag atgccttaga caggaaaata aatttacagg atattcaaat
    11761 caaaacggat gggacgacct ttcagaaatt acaagtaata ggtagccttg atttattatt
    11821 ggggaagcat atttctattg ttggcagagg tgtttactct tctcttcgct atgatgcagc
    11881 tattcgaaca aggaaaaaaa tattggctct gtctttgaaa caaaacggat taatctatat
    11941 ccctatctct ttgttaaacc tatcatcaaa ggaaattgga cctggacaaa aagttactgg
    12001 catttttagc gaggatttaa catccgggga acttaaaatg attatggaag tcatcgatta
    12061 atcattaata gtgatatgcg acgtcatttt gaagtaatta ttctattttg ggttataaaa
    12121 taaagcattt taagacgatt tcaaatcatt catgtgggtt atttatcacg gatgagcttg
    12181 aaatcgtctt ttatacgtat caaattgaaa tgttcggcat acaacctatc gttgttacta
    12241 cattactaat tgtcacttgt taaggaactt ggatcctttc taaacattcc ctagagataa
    12301 attttacttt atccctccgt taatatccaa tttaagcacc tttccgattc agggttaatt
    12361 tgcatatcaa gtgcagcttg tgttctagta agattagccc ttttagtccg gctgagttga
    12421 cttatggata taagatatgg tcatagcaaa tagatactac gtatagtctg ttaatttagt
    12481 gtcattaatc ttaa
//
LOCUS       DAMEEU010000081        12467 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.082, whole genome shotgun sequence.
ACCESSION   DAMEEU010000081 DAMEEU010000000
VERSION     DAMEEU010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.082"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..667)
                     /locus_tag="PB779_002352"
     CDS             complement(<1..667)
                     /locus_tag="PB779_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDE0739858.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            801..1088
                     /locus_tag="PB779_002353"
     CDS             801..1088
                     /locus_tag="PB779_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739859.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            1504..3042
                     /locus_tag="PB779_002354"
     CDS             1504..3042
                     /locus_tag="PB779_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HDE0739860.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            3039..4004
                     /locus_tag="PB779_002355"
     CDS             3039..4004
                     /locus_tag="PB779_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739861.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEENENI"
     gene            3991..5313
                     /locus_tag="PB779_002356"
     CDS             3991..5313
                     /locus_tag="PB779_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDE0739862.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      5376..5480
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            5554..6297
                     /locus_tag="PB779_002357"
     CDS             5554..6297
                     /locus_tag="PB779_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0739863.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            6312..7304
                     /locus_tag="PB779_002358"
     CDS             6312..7304
                     /locus_tag="PB779_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HDE0739864.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            7316..8053
                     /locus_tag="PB779_002359"
     CDS             7316..8053
                     /locus_tag="PB779_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739865.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            8043..8765
                     /locus_tag="PB779_002360"
     CDS             8043..8765
                     /locus_tag="PB779_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HDE0739866.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(8849..9472)
                     /locus_tag="PB779_002361"
     CDS             complement(8849..9472)
                     /locus_tag="PB779_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDE0739867.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQP
                     VVQETVQTEKQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYI
                     GRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            9867..10559
                     /locus_tag="PB779_002362"
     CDS             9867..10559
                     /locus_tag="PB779_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HDE0739868.1"
                     /translation="MKKKFITGGIVVAFLCLIGYTGTRYANEIILWGGETDIDTINEN
                     LTQLDHTLTDKEQAITDLTARLAQKEQTLQDSKADVQEYQTKVNELENQKNQSAAEKQ
                     NLESQLVSKDAQLQSKQNEINVKLDEINQKNDEINHLNADWTARLQEAQAELSELQNT
                     VNGLNQQIATLTQEKTNVETQLTDTQKKLDEATAENSSLKQYIQKLEKAKDEVEDTAD
                     KSQQIVEEHLRK"
     gene            complement(10828..12000)
                     /locus_tag="PB779_002363"
     CDS             complement(10828..12000)
                     /locus_tag="PB779_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HDE0739869.1"
                     /translation="MTQVHFTLKSEEIQSIIEYSVKDDVSKNILTTVFNQLMENQRTE
                     YIQAKEYERTENRQSQRNGYYERSFTTRVGTLELKVPRTRDGHFSPTVFERYQRNEKA
                     LMASMLEMYVSGVSTRKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKN
                     YPYLMTDVLYIKVREENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEY
                     LKERGLQGTELVISDAHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFRE
                     AVKGIFKFTDINLAREAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRL
                     KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
BASE COUNT         4122 a         2109 c         2535 g         3701 t
ORIGIN      
        1 agtgctctaa ctgttcaaga ggatcaagtg gttcaaatgt ttctgtagtc tgttttgctt
       61 ccaattgggg caaaacagat ccaatttcca gatacttcac tttattcaat gtataagata
      121 gaatagaaca gctaagtaat gtatacagaa aatgtgtgag atccaaataa agcaaggaga
      181 caactaaaat accaaaagta atcaagaaaa gacttttgcc aatcttaata tgaaaatatt
      241 tttcaatggc ttgataaatg atatctgttc cgcctgtgct tccgccgaat cgaaagacga
      301 gaccgcaacc aatgccagaa agaatacctg tcatcaaact attgatcagt agactatcta
      361 cagcaaaatg tatatgaagg ctctcccata aatgtaaaaa gaaaactagc gcaaatgttc
      421 cgacgatcgt ccggagaaaa gcgtgttttc caaaaagaaa caatgagata agcaataaag
      481 gtaaattaaa aagcagtgaa gtgacagaag gagcgaatcc aaaaagatta tgcaaaagca
      541 aagcaatacc agtaacccca ccatctgcca gcttagatgg aatattgatt cctgtcacag
      601 ctaatccgta gattcctgcg cctaaaatga ttccgcacaa ttctgtaaat aaatttaatt
      661 ttttcatttc tagcctcttt tcttttgaaa attttcagca acttctttat tatactgact
      721 tatactctta cttcaagagg aaaatgaaaa aaaattattt ttggctgttt ctttttattt
      781 atcaaataag gagtggaaaa atgcgagcag cagacttatt gacaattctt acaaaatcac
      841 ccaaaaaaac agagtatcaa ggagtttttt tggctcaaga acaaaaactg gtgcctgtga
      901 caatggtcca gataaataaa gcaaatcaat ttatcttttt atttgaacac ggcaaagcac
      961 cacttgctat gaaagacatc tttctttttt tgatgaagaa ccgtgagaaa gctgtttatt
     1021 atcagtcaaa agaagaactc attcctcttt atggagtgaa agagatagaa aataaagtgg
     1081 tgatataagt aaaaataaga aaacaagacg tttatgatgt caaaacaacc attttttaca
     1141 tttttggcaa aaaagtgtca tgatacagta taatattcgt tgaacaggcc aataaaggtg
     1201 ttctccccca cgagatttct actttattgg ctgtttcttt ttattaaaat aaaagttgtg
     1261 tgtgtaaaaa agatatagct gattccaagt gacaatttcg tatagatttt tatggtattc
     1321 gtagtgaaaa aacgagaacc aaaaagttga tccgactttg ttgcttggat tctttttttg
     1381 tcagcatatt tagaggtatt tttttctttt ttttgttcgt gctgtaaggt taaggcaaga
     1441 caagttagtt gggaaaaagg aaagaaatgt ttatacttaa agaataacag aaaggaaggt
     1501 cgcatgaata attttataca aacattaagt gaaagaaaag gcgagttgct ggaagctgca
     1561 tttcaacatc tgtccatttc tctcatttct ttgctgattg cagcactgat tgctattcct
     1621 ttagcgattt gggcagccaa tcataaaaaa atggcagaag tcttattgca gatcacgggt
     1681 gtgctccaaa cgattccttc acttgcctta ttaggtttac ttatcccatt tgtagggatc
     1741 ggaactgttc cagcattgat tgcacttgtt atttacgctt tgcttccgat tttccaaaac
     1801 acgtatattg gtctagctga aattgacccg tctattgaag aagcagcggt agcatttggt
     1861 atgtccagaa tgagacgctt gctgaaagta gagcttccca tcgcattacc tgtcattatc
     1921 tcaggtatcc gaactgcctt agttttaatc atcggtacgg ctactttggc agcattgatc
     1981 ggagcaggtg gattagggac atttattttg ttaggtattg accgaaatac acctgttttg
     2041 acattgattg gtgcgatcag ttctgccttg cttgcaatta tattcagcgg actgattcgc
     2101 tggttgcagc ataagaaacc tcgatattcc atcattactt tagcagcagt ggtgtgttta
     2161 tttggcggcg tttctttata tcagtctgcc ttgtttaaaa atgaaaccat cacgattgct
     2221 ggaaaattag gagcggaacc tgaaatcctg atccaaatgt ataaagaatt gattgaagac
     2281 aacacaaaaa cagaagttga attaaaaccg aattttggca agacgagttt tttgttcaat
     2341 gcactggatc aaggtcaaat cgatatctat cctgagttca caggtactgt cctagaaagc
     2401 ttggtgaagg tacctgaagc aatgaaaagt gctgatttga caaaagaaaa aacatatgac
     2461 gaagcagaag aattattgaa taagcaattc gatatgacat tattaaaacc aatggcttac
     2521 caaaatacgt atgccttggc agtcaagaga tcttttgcga acgaacatca acttaaaaag
     2581 atttccgatt tggcagctat ctctgatcag atcaaagcgg gattcacact ggaatttatt
     2641 gatcgttcag atggatataa aggaatccaa gaagcatatg gcttgaattt ttcaagtgta
     2701 caaagcatgg agccaagttt gcgttaccaa gcaatcaata atggagatgt caatattgtg
     2761 gatgcctatt ccacagatag ccagctcaag gagtacgatc tagtgactct agaagatgat
     2821 cgagggttat tcccagctta tcaaggcgca ccgctgatga aaaaagattt tgctaaagaa
     2881 catcctgaaa tcgttaaagc actgaataaa ttaagcggaa aaataacaga ggatcaaatg
     2941 attgatatga attaccaagt caatgtcgaa aagaaaaagc cgacagaagt agcacgaatc
     3001 ttcctgaaaa atgaaggatt agtaaaggag gaagatcagt gactaaatta atcgagttca
     3061 aacatgtgca aaaaaagtat gatggaaagt atgtcatcga tgacctaaat ctggcaatca
     3121 aaaaaggaga aatctttgtt ttggttggtc cttccggtag tggaaaaaca actactttga
     3181 aaatgatcaa tggattatct aaaccatcag caggagacat ctacttcaaa ggaaaatcgt
     3241 taaatgaata taatctgcag aaaatgcggt ggaatatggg atatgtgctg cagcaaatcg
     3301 ctttgttccc gaccatgaca gtcaagcaaa atattgaagt catccctgaa atgttaggtt
     3361 gggaaaagca gaaaagagca gaccgtgtag atgaacttct tcaaaaagtt ggcttatctc
     3421 ctgatattta tcgagatcgt atgcctagag agttgtctgg aggagaacag caacggatcg
     3481 ggatcatccg agctattgct gcaagcccag atgtgatttt gatggacgag ccatttagcg
     3541 cattagatcc gatttcaaga aactcattac aagaattggt tttgtcctta cacgaagaat
     3601 tgggcacgac catcgttttc gttacgcaca atatggaaga agcaatcaag ctaggtgatc
     3661 gtattgcatt tatgaaggat ggagaaatta tccaatgtga cacaccagag cagttattga
     3721 tgaatcctaa aaacgactac gttcggcatt tctttgatga accgaaacag acgaaagagt
     3781 ggcgagtaga agatttagtc gtcaatggat atttcttaaa tgaaatacca gaaaatgctc
     3841 gtcaacaagt ttgctttgat acgcctatga aagaagtata ttcgcttctt tcggtgtatc
     3901 caagcattgt gatagtagaa aagcaaagaa gtattgggtc gctgacaagt aaagaaatct
     3961 ttgctttttt aagtcgagag gaggaagaaa atgaaaacat atgatgcaat catcatcggt
     4021 tcaggtgtga gcggcttaag tgctgcttat ggattgaaag aagcaggtaa aacagtacta
     4081 gtggtcgaag aagatctatg gggcgggact tgtcctaacc gtggatgtga tcctaaaaaa
     4141 gtcttgttaa gtgcagtaga ggcacgtaat cgggtaaaac aattgagtgg aaaaggtttt
     4201 aacgagatcc caactgccaa ctgggaagaa cttcaaaaat tcaaacgaac atttacggat
     4261 ccagtcccag aaagccgaaa aaaacaatta gcagaagctg aaatcgatca tctttcagga
     4321 accgctcgtt ttttggatga ttcatctatt gaagtcaacg aagaagtctt ccatgcggat
     4381 tacttagttt tggcaaccgg gcaaagacct acgatcttac cagtggaggg aaaggaatac
     4441 ttgaaaacta gtgcagactt tttatcattg cctgtactgc ctaaagaaat catttttatc
     4501 ggtggtggtt atattgcttt tgagctagct acgattgcca atgctgcagg gagcaaagta
     4561 accattgtcc atcataatca acggccatta aaagaatttg aggcgtcttt ggtagaggaa
     4621 gccgtccatc aaatggaagc atctggcatt cagtttgctt ttggtgttga aacccaaaag
     4681 atcatttcag aaggtactcg ctatcgttta gtcggaaaag agacggaatt agtagcagat
     4741 atgatttttt gtgcgactgg gagacagccg aatacagaat ctttagcact tgagcaagcg
     4801 aatatcgtct ttgataaaca cggaattgca gtcaatgatt atctgcaaac gagcaatcca
     4861 aaaatttttg cgtgtggaga tattgtttca aggaaaaccc caaaattgac accagtcgcc
     4921 acttttgaag gaaattatgt agctaagcgg ataacggatg caacaagcga acctatcaaa
     4981 tatccgatta tacctacgat cgtctacgcc agtcctaaac ttgctgaagt aggagttaca
     5041 aaaagtcacg cctcttcgtc agatcaagtg gtagagatgg atcttaccag ttggttcacc
     5101 tatcatcgtg tcaatgaacc agttgctaag gctgaattga cctttgacca gcaaaattat
     5161 ttgattggtg ctgcagtgat tagcgagcaa gcagacgaat tgatcgatga tttgacactc
     5221 gtcatcaatc aaaaattgac taaaaaagag ttggatagct atatcatggg gtatccgaca
     5281 ttggcaagtg atctctccta tttattgaaa taatcagcat gataactaaa gcgcttgttg
     5341 ctttttcctt cttgtgctac actttaaaaa atgaatacct gtttctgggg atgtcgtaga
     5401 cgacatgaga gtaagttgtg aacttagacc cattgaacct gtcagttaat actggtgaag
     5461 ggagaaacat agcagacgct tgaagcgggt tactatgtcg tgcccatttc aagcgttttt
     5521 tgttattcat attagaagaa aggaggtaac aaaatgaaga aaaatcttta tccagcagtc
     5581 agtatggcat tcattttaat tatttggcag attgttgtca tagtttggaa aatacctgcc
     5641 tttattttac ccggacctgc tgctgtattt tctgcattag cggcagatgc acaagtatta
     5701 ctttcccatt ctgtcacgac attaaatgaa gcagtgcttg gtttggtaat agctagcgtt
     5761 ctttctttta ttactgcctt ggcaatggat tattggaagt ttttagaaat gtctttttat
     5821 ccgttactag tgatttcaca aatgttgcca atcatggtgt tagggccatt acttacccta
     5881 tggtttggtt tcggtatgct tccaaaagtg atccttgttg tcttgataag ctattttccg
     5941 atcgtagttt ctttttcgga tacattgagg aaagtatcaa aagagcaaat catctttttg
     6001 aaaacgatgg gggcagatac agggaagatt tatcgaatat ataaaatacc agcgggttta
     6061 tccggcttct tttccggttt aaaagtggct gctacttatt gtgtcagcgg agcagtcgtt
     6121 ggagaatggc taagcgctca agcaggctta gggtattaca tgatacgcgt aaaaaacagc
     6181 taccagatcg ataaagtttt tgctgcgatc atttgtgtca ttctattgag tttattgctg
     6241 aatggcgctt gttcattatt gaaaaaaggg tattatcgta tgctttatat tttttaagag
     6301 aaggggatca aatgaaaaaa ttatggcttt tattaccgct actgttgctt ttatccgctt
     6361 gtggcactgc aaaagaaaca agtagcaaac aagaaataaa ggatttgaaa aaagtgacac
     6421 ttgttttgga ttatgtaccg aatactaatc atactggcat ctacctagca aaagaaaaag
     6481 gctattataa agaggctggt ttaaatgtcc aaatcatcga accaggagat aattcgacaa
     6541 gtattggtct agtaggtgcg gacaaagcac aatttggtgt aagttatcaa gaagatgtca
     6601 cttatgctca cgcagatgga cagaatatac cagtcaaagc aattgctaca gtgatcaaac
     6661 ataatacttc tggattcgcc accctatcag acagtaacat ccattcacca aaagattttg
     6721 aaggaaaaac atatgcaggt tggcaaagtc caagtgaaga agctgtctta aaagctgtga
     6781 tggaaaaaga cggcggggac ttttcaaaac tgacaatggt aggaagcaat ggagaagggc
     6841 cagaaagctt aggaaaatcc tcagatatcc aatggtactt tgaaggttgg gatatgatca
     6901 aagcaaaaga agcgggtatt gaactaaact atatcccatt gaaagaatta gatgaacggt
     6961 tagattacta tactccggta attattacga atgatcaact gatcaaaagt gatccagaat
     7021 tggtacagtc ttttatggat gccacgaaaa aaggctatca ggaagctatt aaggatccaa
     7081 atgacagtgc taaactgttg caaaaatatg caaaagaaaa tgatcggacg tttttagaag
     7141 aatcacaagc attcttgtca aaaaattata cggatgatcc tgagaattgg ggattgatgg
     7201 aagaaaaagt ttggcgcaat tatacagctt ttatgcagga aaacggattg atcaagcaag
     7261 atgtaccttc gcaagaacta ttcactaatc agtttataaa ataggagtga tagatatgtc
     7321 aatccaaatc agccacttga atgtagtcat tgaaaacctg aaaatattag aagacatcca
     7381 tttcactatc cctaaagata cctttacatc gattgtcgcg ccaagcggag ccggtaagtc
     7441 aacattgctg aaaactttaa caggagtcca gcctatgact tctggaacga tcaaagtaga
     7501 cgatcaaaaa gtaactggtc tccatacagc atttagttat atgccgcaag aagatatgtt
     7561 acttccttgg ctgagcgtct atcaaaacgt tacgttatat caaaaaatca atcatctaac
     7621 aatcaatgaa gaacaagtaa gggattatct ggatatcttt gggttaaacg gctatgaaca
     7681 ttttttgccg gaacaattat ctggcgggat gaagcagcga acggccttgt tacgaacaat
     7741 catgaatcct tcttcttact tgcttcttga tgaaccattt ggagcgttag atgctatgac
     7801 cagagggcag atgcaagact ggatgttgaa gctgcctaaa aaagcaaagc ggactacttt
     7861 acttgtgacg catgatatcg aagaagcaat ttatttatca gacaggattc ttgtgctttc
     7921 cgcccgtccg gcacatgtga ttgctgagat tcaagtgcct gaaaaacgac ggtcacgtga
     7981 atggctactg cagcaatcag agttgaagca aacgatttat cagttattgg caggtgaatt
     8041 agatgttaag tgatgctcat tgtcatttag atgggagtca gagtttagca ctccttcagc
     8101 aggaacacac gattttgacg atcatcaatt gtgattcgcc agaagaatgg aaggaaaaca
     8161 gacagcttgc agcaagtaag actcaagcct taagttacgg tatccatcct tggaaagcag
     8221 atagctatac gtttgaacaa gttgagcctt ttttgaaaaa agcaaggatc atcggtgaaa
     8281 tagggttaga taatatttgg acgaatgtac cgatgactac acaaaaaaaa gtatttgagc
     8341 gacagcttgc ttttgcagcc ataaatgaga aacctgttgt actgcacaca aaaggatgcg
     8401 aaaaagagat cttaaattat atccaagctt accctaatca ctatttgatc cattggtatt
     8461 cttctttgga ctatcaacaa gactatattg atttaggctg ttatttcagc attggtcttg
     8521 atttgaaaaa gaatccagca gtctggcaac tagctaaagc agtcccaatc gaccacttac
     8581 ttattgaaac ggatggacta catgcagcag agtgggcttt aggggggatt ttttcagaaa
     8641 aagattatgt ctcactgctt gaagaacagt taaagacaat cgctgagatc aaagagctat
     8701 cagttgaaga agttaaaaaa aatacttatc aaaacttgga acgtttcatt agattaggta
     8761 aataaaaaag agatgtgaca caactagtgt cgcacctctt tttggctttc tttgtataaa
     8821 agtaaactgt ttgattaata aatgaatctt agtaccaacc gtttgcttcc cagaatgctt
     8881 tcgccgcttc ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt
     8941 ttgcagcaga gtagtcacca tttaagtaag aagaatctaa ttggtaacgt ccgatgtaac
     9001 gtccgttcgt tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag
     9061 agcttgtgct tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag
     9121 caacaggcgc tgcttgtttt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt
     9181 ggactggtgc ttcttgaacg gctgcttgag gttcagcagc tgcttgtgca gagccttctg
     9241 ttgggattgt taattgttgt cctgagtaaa tcaggttaat atcagaaatt gaatttgatt
     9301 ctgcaatggc attgatcaag gagttatcac caacgtattt ttgagaaatc gttgatagag
     9361 tatcacctga ttgaacggta taagcttcgt ccgcatgagc agtcgttccc atgaagaatg
     9421 cagcgccggc agccaaagtt gttccaaaaa gtaaagtttt aagtgatgtc atgaaaaatc
     9481 tcctttattc gttaaaaagt tttatttgtt gtgttcaacg aggaatactt taacacgtga
     9541 aaatatttca taggtaaaag aagcatgaca atttatgaca aatccgcgtt ttttgtaata
     9601 aatacagtaa tctatgaaat gaaaagggtt acgtttaata aaacttgctt ttttgttttt
     9661 gttcaccata aatatttatt taagaaagta ttaacctgca tttttctcta taaaaaagat
     9721 tttttaaata gataaaaaag gaggattaaa tgagtatttg atagtattta tattaaaatt
     9781 acatatgtaa tttaaaaacg cttgacattg tgtttgagat cacttacttt tagcatgtaa
     9841 aagtattgga ttaaggagct atgcaaatga aaaagaaatt tattactggt gggattgtcg
     9901 ttgcatttct atgtctaatt ggctacacag gcacgcggta cgcaaatgaa attattttgt
     9961 ggggtggaga gacagatatt gatacaatca atgagaatct gacacagctt gatcatacat
    10021 tgacagataa agagcaagcg attacagatc ttaccgctcg actagcacaa aaagaacaga
    10081 cattgcaaga ttcaaaggca gatgtccaag aataccaaac aaaagtaaat gaattagaaa
    10141 accaaaaaaa tcaatcggca gcagaaaaac aaaacttaga aagtcaatta gtcagcaagg
    10201 atgcacaact acaaagcaaa caaaatgaaa tcaatgtcaa actagatgag atcaaccaaa
    10261 aaaatgatga aatcaatcat ctgaatgcag attggacagc aagactacaa gaagcacaag
    10321 cagaactttc agaattacaa aatactgtaa atggtttgaa tcaacaaatc gcaacactga
    10381 cacaagaaaa aacaaatgta gaaactcagt taacagatac acaaaagaaa ttagacgaag
    10441 caactgctga aaactcaagc ttgaaacaat atattcaaaa gttagaaaaa gcaaaagatg
    10501 aagtggaaga tacagctgat aaatctcagc aaattgttga agaacatttg cgtaaataat
    10561 ctttcttaac aagtaaacct aaattagtaa agaagcaaca gtaatctata ctaagtagtt
    10621 cagttttgga gtacaaaatg acaaaatgta cttcaaaatg gactactttt ttcattttaa
    10681 cttacatacc aaattacata caaaatgatt tataaaatgc aattgaaaat gataattgaa
    10741 tgaaaatttg tgattttgtg gtattatgat aatataaagt caagtccaga ctcctgtgta
    10801 aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt ttcttgaaga
    10861 ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat tggctgatgt
    10921 ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat tcagtcgttc
    10981 aattagattg gtactcttta gtcgattgtg ggaatttcct tgtacggtat attgaaaggc
    11041 gtcttcgaat ccatcatcca atgatgcgca agcttttgaa tattttggtt gatcgatata
    11101 atcatgaatc aatcgatttt tagcctcacg cgctaagtta atatctgtga acttaaaaat
    11161 tcctttaaca gcttctctga aagattttga atttttttta ggaatggtgg taaagatatt
    11221 tcttaggaag tgaacttggc atctttgcca acttacgttg gtgaaggatt ttctaatggc
    11281 agagactaat cctttgtgcg catcagaaat aacgagttcc gtaccttgta aaccgcgttc
    11341 ttttaggtat tcaaaaaatg ttgtccaggt ctcttcgctt tcgccacttt gaatcatgaa
    11401 gccgataatt tcacggtcgc catctttggt tattccaatc gctatatgac agctttttga
    11461 gagtactcga ttttcttctc gtacttttat atagagtaca tcggtcatta agtaaggata
    11521 atttttttct gataataaac gattctgcca ctcgttaacc ataggttcta gctgttctgt
    11581 taagctagaa acgaaggact tagagacgga tttaccacaa agttcttcca caatttttga
    11641 tactttacga gttgaaacgc ctgatacata catttccaac attgaagcca tgagggcttt
    11701 ttcgtttcgt tgataacgtt caaacactgt gggtgaaaaa tggccatcac gtgttctggg
    11761 tacttttaat tctagcgtgc ctacacgtgt cgtaaagctg cgctcataat agccatttcg
    11821 ttgactttgt cggttttctg ttcgttcata ttcttttgct tgaatatatt ctgttcgttg
    11881 attttccatt agttgattaa ataccgttgt taaaatattt ttagaaacgt catcctttac
    11941 agaatattca ataatgcttt gaatctcttc gcttttcagt gtaaaatgta cttgggtcat
    12001 gtaaaagtcc tcctgggtat gtttttgtcg ttaaaaacat tgtaccgtaa aaggactgtt
    12061 atatggcctt tttactttta cacaattata cggactttat ctatataaag gcgctgtcag
    12121 agttttttga cttagaacat acattcattc aagagacttt aaacaagcta gcagaacgcc
    12181 caaaaacgga cacacaactc gatttgttta gctatgatac aggctgaaaa taaaacccgc
    12241 actatgccat tacatttata tctatgatac gtgtttgttt ttctgtactg tttcctgagt
    12301 gattagcaga aatataaaga ttaaaatttt aattgattat taggaagaga aggagaatgt
    12361 atcccgaaaa ctttttagtt ggcttggact gaacgaagtg agggaaaggc tactaaaacg
    12421 tcgaggggag tgggagcgaa gcgcacactt gatcttttga acttttt
//
LOCUS       DAMEEU010000082        12376 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.083, whole genome shotgun sequence.
ACCESSION   DAMEEU010000082 DAMEEU010000000
VERSION     DAMEEU010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 12376)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12376)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12376
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.083"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(237..320)
                     /locus_tag="PB779_002364"
     tRNA            complement(237..320)
                     /locus_tag="PB779_002364"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(284..286),aa:Leu,seq:cag)
     gene            848..1348
                     /locus_tag="PB779_002365"
     CDS             848..1348
                     /locus_tag="PB779_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0739870.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            complement(1538..1882)
                     /locus_tag="PB779_002366"
     CDS             complement(1538..1882)
                     /locus_tag="PB779_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HDE0739871.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(2036..2956)
                     /locus_tag="PB779_002367"
     CDS             complement(2036..2956)
                     /locus_tag="PB779_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HDE0739872.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGV
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            3143..3634
                     /locus_tag="PB779_002368"
     CDS             3143..3634
                     /locus_tag="PB779_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HDE0739873.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            complement(3658..6033)
                     /locus_tag="PB779_002369"
     CDS             complement(3658..6033)
                     /locus_tag="PB779_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HDE0739874.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            6359..6985
                     /locus_tag="PB779_002370"
     CDS             6359..6985
                     /locus_tag="PB779_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDE0739875.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            7008..7712
                     /locus_tag="PB779_002371"
     CDS             7008..7712
                     /locus_tag="PB779_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDE0739876.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGAIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            7904..8737
                     /locus_tag="PB779_002372"
     CDS             7904..8737
                     /locus_tag="PB779_002372"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HDE0739877.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            8934..10862
                     /locus_tag="PB779_002373"
     CDS             8934..10862
                     /locus_tag="PB779_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HDE0739878.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            11000..11455
                     /locus_tag="PB779_002374"
     CDS             11000..11455
                     /locus_tag="PB779_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HDE0739879.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            11925..12194
                     /locus_tag="PB779_002375"
     CDS             11925..12194
                     /locus_tag="PB779_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739880.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
BASE COUNT         3782 a         2310 c         2237 g         4047 t
ORIGIN      
        1 agtttagtct ttattcctta actatcgttt gccagtattt cttgtatcag aatctataaa
       61 tctactattt gaatcaatct attaggtttt aaactgtccc accttcacac aaattttttt
      121 tgatttattt gaatctggtt ccgttgttta aaatttttcc tatattcttt tagataatat
      181 gttattttct ttctcatcgc tccaggtgta ccttctcttt ataaaaaaac aaattatgcg
      241 gctaagaaga ctcgaacttc cacgaggtca ccctcactag cgcctgaagc tagcgcgtct
      301 gccaattccg ccatagccgc atcacatctt ttagtttagg attacatgtg ttttttgtca
      361 agaacatatt tttgttcttt ttcatttctg tacgccctcc cttatgccat ctacacaaat
      421 aattcatccg agcaactcca tcatctattg agggttggtg aaaaaatctg ttttatccat
      481 atgatcgatt tcaatgttaa acgaacgact ctgggattag taactatttt atttttttct
      541 tcatttcttt tttcctcttt ttctcgattc agctatcttc tttcatttgg atattgatta
      601 tttcttctgt tgattactat ccttctggaa ttctagacgc tgaagtaatt cacgttttct
      661 ttcttctaga gatcataagt aacgaatgaa cgaacttcaa ataatttttt tattgtaatt
      721 catatttgta ttgttcgatg attcttaata cgatatgaca caataaataa aaataggcat
      781 ggctatttac aacaatagtg ctatagtaga aaacaaatga ataaggttac ttaaagaggt
      841 gaatacgatg aaactgatca aactatggga agcagattta aagaaagctt atcagctaca
      901 aactagcttt ggaccaaatg agagtggatt tatcaacaat gcttatggct atacatttgc
      961 tgaattttta gattatgtaa aaaaatgcga aaaaacgtct ttaggaatcg atcttcctga
     1021 gagttacgtt cccgcaaccg tctttatttt agaaagtgat gaacatgagt atgtaggaat
     1081 ttttaatttg cgccataaac tgaacgaaac attaaggaac ggcgctggcc atattggtta
     1141 cggcatctcc cctaattatc gtaaaaaagg atatgccaca caaggattag cattagtact
     1201 acaagaggca aaaaaaatcg gcattgatga ggcacttttg tctgtaaata aaaaaaatct
     1261 tggcagtctt aaagcacaac aaaaaaatgg ggctgcgatt tatcgtgaag atgagaaaga
     1321 atactatacg aaaatcaaac tgatgtaaaa aagaaggatt ccaaaaggaa agggatttga
     1381 atgtccttta tcaatagaac acatttattt aattaactta taatatagca gacaaaattt
     1441 tataaacaaa gaaacctttt atctcttttc ttctagaaag gataaaaggc ttttttgttt
     1501 ttcctatttg cttctcatag ctagtcagcc aagatttcta tcgtatcccc aacgcaatcc
     1561 gtgcataacg gctcatctta tctgtcgtcc atgctggata ccagactagt ttgacttctg
     1621 ctttcgttac ttctggcact tcttttaatg cgtcatggat agattctgtt aaaatatctg
     1681 ctaatggaca gcccatagtt gttagagtca tcttaatgac tgtttctcca ttttcaggat
     1741 tgaattctat atcataaatc aagcctaaat tgacgatgtc gattcctaat tcaggatcaa
     1801 tcaccatttc caaggcagca agaatacgtt ctttgattag ttctatttct tgtccagacc
     1861 gttcttggtt tgcttcgctc atcgtacgac actccttaac acgattttta tttatcatac
     1921 tcttttttta gctgcttgta aatgagaatt tagaagtaag attctcgttt aaatttataa
     1981 aaatgttctt attagatgta atagattaaa tttattctaa aataaacctg attcctcatt
     2041 ttttttgtga acgatttttt atttctggca atacgccagt tgttcgatac attttttgtt
     2101 cgttttcatt tgcaaaccgg ccaaatactg aatgagttgg taaaatattg ataaatgcat
     2161 cgtcgtcgat ttcatgaacg atctgatcaa gatcatacat ttcgtagcgg gtgatgacca
     2221 tcatgatcat gttcccttgt ttttttgaat agccaccgac agacggcagt aatgtcattc
     2281 cacgtaccat ccgttttgct agttcttctg ttacctcttc tggcttgacg gtaacgatca
     2341 ttgctgttac tttttgatga ctcgtgtgga tggcatcaat tacttgagtc attgcataaa
     2401 tggaaataat cgtatacaag gcactttccc agttaaagaa gaagcctgcg atgactacaa
     2461 tgataccatt tagaatcagc atgtagtttc cgactgtttt tccagttgtt tgtgaaagta
     2521 caagagagat gatatccatc ccaccagttg taaagcccat ttttaaagat aatcctacgc
     2581 caagacctaa taaaacaccg cctactaggg cattcatcaa aatattatca gtgatctgtc
     2641 cgactggaag cagcatcgtc atcaccgata cacatacaac attcacaaaa ctaaggatcg
     2701 ttgctcgttt tcctactttg agaaacccta atacaaacac agggatattc aaaagaaaaa
     2761 taaatgttcc tgtgtctatc ttgatatgaa accattcata taaaagcgag gaaatgattt
     2821 gagcgacccc attcatccct gcagaaaaga cattggctgg aatcaaaaaa taatttaaag
     2881 cgaccgcagc ggtcaatccg gttatcaaaa taaccactat tttctttaat ctttcatttt
     2941 tatgatacgc agtcataatt ttactcacaa gcacctctcc cctactttgg tattccaaat
     3001 gtaagaataa cagtttatct attaaaataa aatacttcga actcaaatga gaagaatttt
     3061 agcaaacagg taagaatctg ccctaatcct atgataagat agatgtatgg taaatattta
     3121 tatgtatatc aggagggttc ctatggcaaa agatgctagc ttcgacattg tatcagaagt
     3181 caatacagaa gaagtaaaaa atgcgattca gcaaacaaca aaagaattgt ccaatcgctt
     3241 tgacttcaag gattctacag tagaaatcaa attagagaac agcaatctag ttgtattgag
     3301 cgatgatgat ttcaaaatcg aacagatcaa agatgtatta tttggtaagc tgatcaaaag
     3361 aaatgtgcca atcaaaaata tccatttttc cgaatcagaa cacgctctag gtggcaaagc
     3421 tcgacaaact gccgatttgg tcaacggaat cgatcgtgaa aacgcgaaga aaatcactac
     3481 agctatcaaa aatgaaaaac tgaaagtaaa agcacaaatc caagaagatc agattagagt
     3541 gacaggtaag aaccgtgatg atctacaagc tgtgattgct ttattacgta aacttgactt
     3601 accaatcgag ttgcaattca ctaactatcg ttaatcaaaa aacgaggctg acgtctgtca
     3661 ttcctcgttt ttttgattta ctgcttcttt tgataaccaa aaacgctgta ttccttcttc
     3721 caattcccca acacttcgta cttctcttgc tgtttgccaa tgttgtggga ataaacgtcg
     3781 ataagaaaaa ctagaaaatc gttgatctgc caatacaacg attccttgat ccgccatgcc
     3841 acgaatcact cgaccaccag cttgcaagac tttgttcatt ccaggaagct gataagcgta
     3901 agcaaatcca aggtgttcct tctcatcata atatgatttg atcagttcct gctcatgatt
     3961 catctgcggc aaacctacac ctacgatcat actgccgatc aatcggtccc ctctcaaatc
     4021 gattccttct gaaaaaatcc cgccaagtac gcaaaatcca atcaatgttt cagcgggatt
     4081 tgtttgaaat tttgttaaaa atcgttcgcg ttcttcctca ttcatgtccg tttcttggat
     4141 tagcacattg ctgtcgggat attgctgtct gaatgcttcc accgcaagat ctaaatattg
     4201 ataagaagga aagaaaacga aataattccc gacctttcca tcagcaaaag catgaatcgt
     4261 ctctactaat tttgccagac tgtgttccct ttttcgataa gtcgtctcta ggtaatttgc
     4321 gatgaaaact tgctggtttc cttctgggaa aggactcggc agtttgtaag ccagactttt
     4381 ttgtcccccc agtgtttcct gataataaga gagtggtgaa aaactagcag aaaaaagaat
     4441 actgcttttt cctttatcca acgactgctc aagaaacaag cttggatcaa tacaaaactc
     4501 ttttactatc agatcgcgat acgttttttc gactgttgtt tcgtagtgat catcataaaa
     4561 ttcactgacc ttcaaaaaat gaagcaaatc aaaataataa ggaagcaatt gttcttgtga
     4621 tgggtgctca ggaaattctg ccagccattc tttaattttt tcgcttaatt gataacctgc
     4681 ctttactaaa gattcagccg gtgctttttg atgatgataa tcccaatgat cttcttttgc
     4741 tatttctcgg atcgaatcaa attcttttaa tagtttgttg aaacggcgat gaagtttttt
     4801 gaattccttt ggtatagctt ccttacttcg tttcgttttt tcataagata gttctgccga
     4861 atacatctct cgggaacgat tcaccaaatt atgtgcttcg tcaatcaaaa acagatagtc
     4921 ctcgtttttt tcatcttcaa aaaaacgtct taaataaaca gttggatcaa ataaataatt
     4981 gtaatcccca atgattacgt cacaccagat actgacatct aatgatagtt cgaaaggaca
     5041 aagtgtatgc tttcttgcat aagtttcgat gacttcacga gtgatctgat tctcatgatt
     5101 caaaagatcc cataaacctt cattaatccg attgtaataa ccattggcat atgggcactg
     5161 atctggatta caggtcgtct catctaaaaa gcagatcttg tctttcgccg tcaaagtgac
     5221 actttttact tcagctcctg tatcttttaa tgctgtcata gcatcttcag ctacttgtct
     5281 agttattgtt ttagccgtta gataaaagat cttttctccc tcttcttccc ctacagcttt
     5341 caaagcgggg aataacgtag agattgtttt tcctgttccg gtaggtgctt ctacaaacaa
     5401 tttctgtttc gtacggatcg ttttataagc agctaccgct agttcacgct gacctttcct
     5461 atactcatca tgggggaatt tcaaagccat caaagaggca ttgcgtacag tgcgccagtt
     5521 ttcttgaaaa acaagccatt ctttataatc ttcagtcagc tttttaaaaa aagtttctaa
     5581 ctgctctctt gtctgatgtt caacctttct cgtgatcact tcttctgccg tctggaagta
     5641 agtcaattgc agatttattt cttgtaaatc atgttcttga ctatagatat aggcatacac
     5701 ccttgcttga tgaaagaaaa gttccacttg ttctggttct aaatcttcaa atcgtggttc
     5761 ggaggttttg atttcatcta tataataaat accgtctctt ttgaaaatac cgtctgcacg
     5821 gccttcaacg atcaggtaat attcatctaa ttgaactgtt gtttttaaaa agacttcttt
     5881 ttcatagttt tctcccgcat ctttttggag cttgcggtgg attctcgctc cttctaatgc
     5941 agtatggtta ctttttttac gattgtcgat acttccacgt cgcaaaataa attctactaa
     6001 gtgccgcaca gatatttttg actgtttgat catttccacc acctctttct ctctaagatt
     6061 acctgaaaaa acctagttta gcaaaaagag ctctctttcc aaacataaaa aaacaccctg
     6121 ctgattaggc agggatatag gatatagaat ttggattttt ggatgaatct aatgtaacaa
     6181 ggacatatta aaatgctatg aaaacttact ttccttctct ttagaatatc caaatacttt
     6241 tcatatagtc tgataattca gataagtaaa gagaaataag tacctgtttt tgtttcctag
     6301 caatgaatgc gttatactaa tggatgaaag aagttttggc tatcaaggag gaatgcacat
     6361 gcatatcgaa agattaaaaa caggaatgat tgaagaaaac tgttatttgg tctacaacga
     6421 agaagcactt ttgatcattg accctggaga agatgcggaa cgaatcaaac aagaaatcaa
     6481 aaaaacaaac caacagccgg tagcgatttt gcttacccat actcactacg atcatatcgg
     6541 tgcagtggaa cctttacgcg cgtattatca aatcccagtt tatgtcagcc cactagagca
     6601 aaaatggcta ggtgatccga ttttgaatct ttctggactc ggtagacatg atgatattgc
     6661 tgatgttatt gtctcgcctg cagaatatga atttgaaatg aaaacttata ctttaggaaa
     6721 catgtctttt cgcgtcgtcc ctaccccagg gcattctata ggaagcgtca gctttatttt
     6781 tgatgatttt gtcgtttctg gcgacgccct gtttagagga agtatcggta gaaccgatct
     6841 gtatacaggg aatttagaac aattacttca tagtattcgg acccagctgt ttgtattacc
     6901 tgatgaattt gcagtctatc caggacatgg cgatgcaacg acgattgaac aggaaaaaag
     6961 gacaaatcct tttttcaatc gttaaaacga cttaggagga gaataaaatg acagaaacta
     7021 cactttatat cgtacgacac ggaaaaacga tgttcaatac aattgaacga gtacaaggct
     7081 ggtgtgatac acccctcaca aagcaaggac aagaaggcat tcattattta ggtcgcgggt
     7141 taaaaaatgt cgacttttca tttgcttatt ctagtgacag tggtcgtgca atcgaaactg
     7201 cccgtattat tctaggagaa cattctaagg gaaaagaaat tccttatttt attgaaaaaa
     7261 ggattagaga atggtgtttc gggtctcttg aaggtggata tgacatggaa atgtggggtg
     7321 cgatccctcg tgtattgaat tttaaaacat atgatgaaat gtttaccaca gaagtttctt
     7381 ttgaacaaat tgctaatgct gtatacaact tagataccgc tgggtgggcg gaaacttatg
     7441 aaacattgcg agaccgtgta tggacaggat ttgaagatat cgcccatcac tgcgaaaaaa
     7501 atggtggtgg aaatgtttta gtcgtatctc atggtttgac gatcgccttt ttgcttaatc
     7561 tgatcgatcc taaacagcct gttcgtgctg ggcttttaaa tggcagcgta acaaaggtca
     7621 cttatgcaaa cggtcgattt tctatccacg gcatcaatga tacgtcttat atcgataacg
     7681 ggaaaacaca tagtcgcgac tcgtttctat aatggggata ttttaatttt taccagagaa
     7741 tcataaaagg caaagtctga acgagggctt tgtcttcttt tttctcttcg tgtacttatc
     7801 tgctttattt ctcaagtttt tcttaatatt aaaaaacaga ttgggtttct caaaaaataa
     7861 cggtatacta taagatgtat cttaattggg aaggaaggaa tttatgtttt ttgcaaatat
     7921 tatcaaagca gtgattctcg gtattattga aggaataacg gaatggctgc ccatcagtag
     7981 tactggtcat ttgatcctag cagatgaatt catcaaactg gatgccagtt cacaatttat
     8041 gtcgatgttc aatgtcgtta tccaattagg ggcgatcttg gctgtcgtcg ttctttattt
     8101 tcacaagtta aacccatttt ctccaagtaa atcaacggta gaaaaaaaag atacgtggac
     8161 actttggttt aaagtgatcg ttgcttgcat accagccatc atcattggtt tgcctttgga
     8221 tgattggtta gaagcaaatt tccacaagtt cttaccagtt gccattgttt tgatcgttta
     8281 cggtattgcc tttattattg tcgaaaaacg caacaaaaac aaaacacctc gttggacttc
     8341 tctgaatgac tttacgtacc aagcagctct tcttgttggg ttattccaag tcttggcact
     8401 tgttcccgga acatcccgtt ctggcgcaac gatcctagga tctatcttga ttggtgcttc
     8461 gcgttttgtc gctacagagt tttcattttt cttagggatt cctgtcatgt ttggcgcaag
     8521 cggcttgaag atcgtcaaat atttagctga agggaattca ttcaaaatgg aagaaactgt
     8581 tgttcttctt gtaggaacat tcgtatcttt tgtggtttcc gtcttagcta tcaaattctt
     8641 actaagctat ttgaagaaaa acgactttac cgcttttggc tggtatcgta ttatccttgg
     8701 tatcattttg attggttatt ggtttattgc aatgtagaaa aaaccagaac acttctctta
     8761 tttgagaaat gttctggttt tttattttct ttaataataa tcattataaa taataaaaac
     8821 aacatcaagc ttaatcacca aatgataacc attatcgttc tcatttagct gttattatta
     8881 tcaattacat ttttattatg ctatccttgt tttgacaagg aggtctaata acgatgacta
     8941 atcagaaaaa agcttttgca gcaacaatcg gctgcctttt atttatgatc ttcggtttta
     9001 tcttcgaccg attctctctt accatcaccc cactttttta tatcagtgcc attatcatcg
     9061 gtggatataa acaaacatcg gaaggcttga aagaattgtg gaatgatcgg acactgaatg
     9121 tggatttatt gatggcttta gctgctattg gtgcctgttt gatcggtaat tactttgaag
     9181 gagcaatgtt gacattcatc ttttgtttaa gcggtgcatt agaggaatac acaactaata
     9241 aaagtcaaaa agaaattact gctttgatga atcttcaacc acaaaaagcc caattattaa
     9301 aagaaaatgg acaaatgcaa gaagtagatg tttctcaact aaaggtggat aacttggtat
     9361 ttgtcgctaa aggagcagct gttccgatag atggcttttt agaaagcaca caggcaacga
     9421 tcgatgagtc tgcattaagc ggtgaatctg tgcctgtaga aaaatattta ggcgatgaga
     9481 tgtatgcagg aacgctgaat caaggaaatc ccatcacgat tcgagtaaca aaaacgagtt
     9541 ccgaaactgt ctttgctaag attatccaat tagtagaaga agcgcagaat acgccaactc
     9601 aaacagcttc atttatcgaa cgaatcgaaa ataattatgt aaaattgatt ttgcttgctg
     9661 ttcctctaat gatccttctc ccccactttt tcctaggttg gagttgggat gaaagctttt
     9721 atcgaggaat ggtattatta gttgtggctt ctccttgtgc gcttgtcgca tctgctacac
     9781 cagcttctct agctgctctt tcaaattctg caaaaaatgg gattttaatc aaaggcggta
     9841 tccatttaga aaagctttct gaattaaaag cgattgcctt tgataaaaca ggaacgctca
     9901 ctaaaggaaa accagttgta actgacagct ttttctttga tgaaaaggat ttggcacaac
     9961 aacttcttgt tgctatggaa caaaaaacga cgcatccact tgctcatgcg attttgcaat
    10021 atttcgattg cacaatacct gaagaaatcc aatacttacc aatagaagaa attactggtt
    10081 ttggattaca aactacctat ttaggtgcgc aatggaaagt tggcaagcac gcatatgatc
    10141 ctgagacgat gataatcagc aaagagattg cggaaatgat cgaacgtttg gaaaatcaag
    10201 gcaaaaccgt gatttatctt tctaaagatc agcagttaat tgctgtttta ggtctgctag
    10261 atattccaaa agcaaatacc caacaagtaa tttcctactt taaatcccaa aacatccata
    10321 caagtatgat aaccggcgac cattctggca cagcaaaggc cattgctgaa caagtaggga
    10381 ttgaacatta ctatgcaagc tgtactccgg aagaaaaaac acaactagtc aaaaaagaga
    10441 atgaacttta ccaagtaaat gcgatggttg gtgatggagt caatgatgcg cctgctttag
    10501 cagccgcttc tttaggtgtc gctatggggc aagggacaga tgccgctatg gatatcgcag
    10561 acatcgtctt aatgaaaagc gacttaaata aatttgtcta cagtcatcgg ctatctttaa
    10621 aaatgcggcg gatcatcaaa caaaatatta ttttttcgat tcttgttatt ctcttgttga
    10681 ttgcttctaa cttcctgcaa tttttaaatc tacctcttgg agttgtagga cacgaaggaa
    10741 gcacaatatt ggttattctg aatggcttgc gtttactaag acctttacct gatctttctg
    10801 attcttcaaa aaaatgtaag tcttgtccac tatacaaagc gcggctgtct tctgtcaaat
    10861 aagcaaagtg tttttttatg attttgttta ttttatgaaa aaaacagctt atgaataggt
    10921 cttgaaggat gaattcctac ttttgtaact ttctaaaaac atgttatgat tgtttcgaag
    10981 aaagtgagga atatatttca tggaaagttg gcttttttta ggaattattt tacttgtagc
    11041 aattttagct aaaaatcaaa gtctgatgat agcggcagct tttgttttga ttatgaagct
    11101 cataccagcc tcccgttcct ttttcccttg gcttcaaggc aaaggaatca atattggggt
    11161 gacgatcatc acagcggcta ttctaatccc tatcgcaaca ggagaaatcg gtctacgtga
    11221 tctattagaa gcctttaaat cccctattgg ctgggtagct gttttttgcg gtgggctagt
    11281 ggctgtctta tcttccaagg gtgtaggatt gattgcttct gatccacaaa tcactgttgc
    11341 acttgttttc ggcacgattt taggtgttgt cttcttaaga ggaatcgccg ccggaccggt
    11401 cattgcttct ggtatcactt actgtatctt acaagtattt gctttaggaa aatagaacaa
    11461 attttgtcta ttttaggaga ttcttaacac ccccaattta ctgatccgtg atatactgac
    11521 aacgaggtga tacaatgttc gaaaaattaa agtatttcat aggaacaatc ggctggtttc
    11581 ttctagcggt acttttgatt ctgggcttag cttatctatt atttcctgat ttgatacaaa
    11641 atgtgtttga tactgctttt tgattgacct attaaaacga tataggggat gctcctgcga
    11701 tgcaggggct ttttttaatc aatgttttgt aataatttag gccgtgccaa tgagacttcc
    11761 tatagaattc gatgctcttt tttctttttg gctcttctgc tcttttttgt tatactagat
    11821 tacagtggac aaaagaaaga atgatcgcat ccacttcaac gaatatcaaa atggaagaat
    11881 tagtgcctgt tttcaggtta ctttgaaaag aaaggaagac gcttgtggaa acttttgaag
    11941 gtcttttaat tgatacgtac gttttacaag aacagccaat gatgctgact gggatcaact
    12001 tgcagcttga ggaccgtgtg atcaatggcc tgcttaaaga tcgctatttg gcaaaatata
    12061 tcttacgttt gcccctaaat aaatatgtgc tggaagtaag tggcaaatgg aaccgtcgga
    12121 accagttggt cataaaaaaa atgttgataa aaaatatcga tgaatacatt aaaataatcg
    12181 gtacaccaga atagccttta ctgatcaaag gatactggtt ataaaataac tgcagtttct
    12241 taatagaaaa acaaagaaca acagggaatc gtatcccttt tcaaaaaaaa ctttgcaaac
    12301 ggttctcttt gttatataat aacttagtac caaacattcc cattcaaact ttgtttaaat
    12361 agataaataa aaatct
//
LOCUS       DAMEEU010000083        11600 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.084, whole genome shotgun sequence.
ACCESSION   DAMEEU010000083 DAMEEU010000000
VERSION     DAMEEU010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.084"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(222..707)
                     /locus_tag="PB779_002376"
     CDS             complement(222..707)
                     /locus_tag="PB779_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HDE0739881.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    797..1142
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            1187..1828
                     /locus_tag="PB779_002377"
     CDS             1187..1828
                     /locus_tag="PB779_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HDE0739882.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            1847..2482
                     /locus_tag="PB779_002378"
     CDS             1847..2482
                     /locus_tag="PB779_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HDE0739883.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            2500..3315
                     /locus_tag="PB779_002379"
     CDS             2500..3315
                     /locus_tag="PB779_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HDE0739884.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            3634..5070
                     /locus_tag="PB779_002380"
     CDS             3634..5070
                     /locus_tag="PB779_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0739885.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            5259..7706
                     /locus_tag="PB779_002381"
     CDS             5259..7706
                     /locus_tag="PB779_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDE0739886.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            7936..9003
                     /gene="rlmN"
                     /locus_tag="PB779_002382"
     CDS             7936..9003
                     /gene="rlmN"
                     /locus_tag="PB779_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDE0739887.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(9196..10299)
                     /locus_tag="PB779_002383"
     CDS             complement(9196..10299)
                     /locus_tag="PB779_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDE0739888.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            10851..11399
                     /gene="aac(6')"
                     /locus_tag="PB779_002384"
     CDS             10851..11399
                     /gene="aac(6')"
                     /locus_tag="PB779_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDE0739889.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         3849 a         1956 c         2502 g         3293 t
ORIGIN      
        1 ttccgattta taatcgaaaa aagaagcatt tttatatatg cttctttttt cgtagaatca
       61 ataaatatgg atttggctaa ctatggaaga atactcgtat tagttttcag cgttcatact
      121 agttgttaca ttgtttgatt ggccaaaaga atttctgata tattttgtgc taaataaaga
      181 aaaagacgct tgaattggga aataagaaaa ctactctatc attacaaatt ttcataaact
      241 ggcagatgtt ctaagtaaac aagtatcttt tcaaagtcgg aaaaatccat aatcaacgta
      301 gtggtattga tatttggatg aaagcctacg gtatcttgac gatcaatagc agcatcgatc
      361 acgacttgga tttttttctc tttgtcgtgc atcaatgcta atggagtcac tgtacctgct
      421 ggaacgccta ggaggtcagg aagctgttct tcagaaacaa aagataagcg cttttctttt
      481 aattgttcag ctagttgttt taaatcggcg tgcttttcat caggcaagat gacaagatag
      541 atttgttttc cttttcttga tttcaataat agatttttta cttgcggacc aggtagggaa
      601 aaagggacat ttttgactga cgtaatcgca ggatgatcga ctttttgaaa agagataccc
      661 agttttttta gtagttcata agcttcttgt tcggttgcac gactcatcgc gcatcaccct
      721 ccttttttta ttagtgtatc ataaaaaaga gttgacaaat gaaaaataat catgtaaatt
      781 acacgtaaag ttaaaacaaa tgacatcgaa aagaagagta gccgttaggt gtttttagag
      841 agtctctggt tggtggaaag aggcagcagt taaccgtgaa acacatcttg gagtcgattt
      901 tctgaagcgt atagtaggaa aatccgggga gcccgttaca gctgcggtcg ttgctagatg
      961 accagataag gctggctttt ccgtgaggag tcggtaaaaa aaggtggaac cacgtgatta
     1021 acgtcctttg atcttcggat caaaggactt tttgttttca tctgaacggc aacgactgtg
     1081 tgaggttttt tctgcaagga aaaaataaac agaggtggaa ccacgtataa tacgtcctct
     1141 tggcatttgc caagaggatt tttttatttt aaaggaggaa aagaagatgg agtatttgat
     1201 tgaagttatg ccgcaattat tagtaggagc actcacaaca ttgaaattat ttttatttac
     1261 cttgattggc tcattaccat tagggattgt tttagcatta ggattgtctt tgcattttaa
     1321 gccgctacgc tacttgcttc aaacatatgt atgggttatg cggggaacac cgctgttgtt
     1381 gcaactgatt tttatttttt atgggttgcc gacgattggg atcgtttttg atcgtttcga
     1441 agcagcactc attgccttta tcttaaacta tgcagcttat tttgcagaga tctttcgtgg
     1501 agggatacaa tcgattcctc aaggtcaata tgaagcagcg caagttttgc aattaagtcc
     1561 ctttcaaacg gtgacgaaaa tcgtcatccc acaagtgaca aagattgttt taccttctgt
     1621 agggaatgaa gttatcaact tggtcaaaga ttcttccttg atctatatat taggtttagg
     1681 tgacgtaatg cgtgctggga aaatcgcgat ggaacgcgac gcgactttac tgcctttgct
     1741 aggcgtggca atcatctatc ttacattgac tggtattcta acaatcgtaa tgaaacaagt
     1801 tgaaggaaaa ttaaattatt accgctaact gataggagga agaaatatga ttgaattgaa
     1861 gaaagtgaac aaagcatttg gtgaaaaaaa aataatcaaa gatttgaatc taatcattcc
     1921 agatgggaaa acattagcta tcgtaggtcc ttccggtggc ggtaaaacca cgcttttacg
     1981 tatcttggct ggcttagaaa gttctgacag cggagaattt tatttagacg gtgtaccgtt
     2041 caacccattc gagcttaaaa tgaaagaaca agttgtagga gtcgtattcc aagacttcca
     2101 gctatttcca catctgaata tttttgaaaa cattacctta gcaccaaaaa tggtattgaa
     2161 acagacaaaa gaagaataca ccaaaaaagc agaagaatta gcggcttcat tagggattag
     2221 tgatttattg aatatctatc cttatcagct ttctggcgga caaaaacagc gggtagcgat
     2281 tgccagagca ttggctatga atccacgggt attggcttat gatgaaccaa caagtgcttt
     2341 agatcctgaa ttacgccagc aagtcgagcg tttgatccta tcattgaaag aagatggggt
     2401 aacccaaatt attgtcaccc atgatttagt atttgcagaa aatgtcggtg atcaattact
     2461 aaaagtttcc ccaattcatt aagaaaggag aagatagaga tgaaaaaaac cagttttcta
     2521 ttcgctttga tcgcaggtct tcttcttttt gcaggctgtt cgaacaaaaa aacttcagca
     2581 gataattggg cgactatcaa cgaagagaaa aaaatcgtta taggtttaga cgatacattt
     2641 gttcctatgg gatttagaga taaagacggg aagctcacag gatttgatat tgatttagcc
     2701 aaagcagtct ttgaacaata tgggattacg gtagactttc agcccattga ctggtcaatg
     2761 aaggaatttg aactgaacaa tggaacgatc gatttgatat ggaacggcta ttccaaaacg
     2821 ccggcaagag aaaagaaagt gcaatttaca aaaccttata tggaaaacga tcaagtgctg
     2881 atcacaccta aagaatcagg aatcacaaac tttggacaaa tgaataataa gagattaggt
     2941 gcgcaaaatg ggtcatctgg ttatgatgta tttacgaaac aaccagaagt attaaaagag
     3001 atagtcaaaa accaagatgc tgttttgtat gatagtttta atgaagcatt gatcgatctg
     3061 aaaagcagac gggtcgatgg tctgctgatg gataaagtat acgcagacta ttatttgaaa
     3121 caaagaaacg aactagaaga cttcaacata acaaaaggtt cttatgagag tgaggatttt
     3181 gcagttggtg cacgcaagtc agatagtaca ttagtgaaaa aaatcaatga agccctagat
     3241 caactagaga aaacaggtga attccaaaaa atatccgata aatggtttgg cgaagatgtt
     3301 acgccgagaa attaacaaat aggggactgt gacaaaagac gtgtcacagt ccctttttcc
     3361 gaataaacag tgttctcctg ccaactcctt gtgactcgga gctgaatggc aggctcacaa
     3421 cctcttggta aacggtgttc aaaagccagt ttttcggtat taagccaaat ttatgcaaaa
     3481 atgtagaaag ccattttcac aaaatttttc ttactactcg aaactaagcg actttttcac
     3541 aacctccttt acataatttt attttgttgt ggaaggggtt tcgtgttatt ctaaaagagg
     3601 aacgattgaa ggttatagga aaggaagaga tgaatggaac acaaagaact tacctcattt
     3661 ccaaaagatt ttctgtgggg ctctgcttct gcagcgtatc aagtagaagg agcttggcaa
     3721 gaagatggga aaggagaatc agtctgggat cgatttgtac ggatacctgg aaagacattt
     3781 aaaggaacga acggtgattt ggcagtagac cactatcatc gttataaaga agatattgct
     3841 ttaatgaaag aacaaggtct gaaagcttac cgcttctctg tagcttggac acggattttt
     3901 cctaatggac gaggagaagt caatcaagct gggctcgctt tttatgagag attgatcgac
     3961 gaattgattg aaaacgatat tgaacctatg ttgactttat atcattggga tcttccacaa
     4021 gcattgcaag atgaatataa tggttgggaa tcacgtcaga tcattgaaga tttcactcat
     4081 tatgcagaaa cattatttga ggcattccgc gggaaagtcc attactggat tagtttgaat
     4141 gaacaaaata tcttcacttc attaggttat ttgttagcag cacatccgcc aggtgtgaca
     4201 gacccgaaac gaatgtatga agttaaccat attgctaatt tagcaaatgc atctgtcatc
     4261 aataaatttc acgagttaga aatgcctgga aaaatcggac caagctttgc gtatacgcca
     4321 aattatccaa ttgacagtaa tcctgaaaat gttctggctg ctgaaaatgc agaagacctg
     4381 atggccaatt attggatgga tgtctatatg tggggaaaat atccgattgc tgccatgagg
     4441 ttcttagaag aaaaaggatg ggcaccaacg attgaagctg gcgatgcaga attgctagaa
     4501 tctgctaaac cagattttct tgggatcaat tactatcaaa cggcgacgaa tgcattcaat
     4561 ccattaaacg gagttggtgc tggaaaaatg aatacgacag gaaaaaaagg ttcatcagaa
     4621 gaaactggag ttcctggaat gtataaaaaa gttgagaatc catttgtcga acgaacaaat
     4681 tgggactggg agattgaccc agaaggatta aggatcggac tgcgtcgtat cacaagccgt
     4741 taccgcatgc cggtactgat tacggaaaat ggcttaggag agtatgacaa gttgacagaa
     4801 gataaacaaa tccatgacga ctatcgaatc aattacttac aaagccacgt caaagccatc
     4861 aaagaagcaa tttcggatgg agcagaagtc ctaggctatt gcacctggtc ttatacagat
     4921 ttgcttagct ggctgaacgg ttatcaaaag cgatatggat ttgtatatgt tgatcaagac
     4981 gaaacacaag aaggatcttt ggaacgatat aagaaagaca gttattactg gtaccaaaaa
     5041 ctgattgaag aaaatggaga gaacctttag ttcacatact taaaacaaga aggtacggct
     5101 ggatatggcc gtgccttttc ttgataaaat catttagaaa ttaagaaaaa ctgtaaaata
     5161 agctgaaaaa tgaaagaaag cgtcagttct ttcaaacaaa actttagttc ccttactttt
     5221 ttttgtataa tgaaacttga tgaaatgagg gataataaat ggcacaaaag aaacggccta
     5281 ctaaaaaaag gaaaaagacg aaaaaaacga aaaagcaaaa acagcagcag gaacaaatgc
     5341 tgacgattgg tgttgggttt gccttgattt tatttgctgt cttcggcttt ttaaaattag
     5401 gttttttagg aatattgatt gcaaacggct ttcggatcat tgcaggaaat acttaccaaa
     5461 tcctctgtct tttattagcc gtattaggat tttggattgt cattaagaat acagagtttt
     5521 caattggtaa aaaccgacgc tggtttggcg gcatactctt ttatttcggt atcttattat
     5581 tgttacatgc ccatttattt ggcaaactcc atactgggga accaaatatc atggggacga
     5641 catgggattt gttagccagt gatataaaac aaagtcaagt agacaataac gttggtggtg
     5701 ggatgattgg agcaatcctt tatcatttta cttacttctt gattgcacag cctggaagtt
     5761 atttagcagc agtgctatta ctggcaggag gagcattcct gttcagtaat ctggaaggct
     5821 atcagctgtt aaatggtatc caatcaattg gagaacgagt acaggaatta ttggaaggtg
     5881 atcctgccaa gcaagctcga aagcaagcgg caaaggaaga gagaatgaaa cagcgcgcag
     5941 aagcgaaaga agcaaggcgc ttagctgcaa aagaagctgc agaaaaagaa gctgcagaat
     6001 atgagaagaa aaaagcggtg agccagcaaa gggaaaatac tgctgatgaa tggcaggaac
     6061 cagaaaatac agagccggag cagctaagtt ttgttccaat cgacagtttt caagaaaata
     6121 tccatcctgc gaatctagag aaaccagtac cagatacacc aaaacagacc aatacagcag
     6181 aaggtttttc agatgagttg ccagaggatg acggtacctc attagaattt gagattgaag
     6241 cagaacagga aaatcaagac tatgaattac cgacagttga tttgcttgat tctataccaa
     6301 ctgtggatca aagtgatgag tataaaaaaa ttgaaaaaaa tatcggcgta ttagaacaaa
     6361 ctttccaaag tttcggtgtc gatgccaagg tcgtcaaagc cagcttagga ccatccgtca
     6421 caaaattcga agtccagccg gctgtagggg taaaagtaag taaaattgtg aacttaacag
     6481 atgatatcgc gcttgcttta gcggcgaaag atgtccggat ggaagcaccg attccaggta
     6541 aatcactgat tggtattgaa gtaccaaatg gaaagatcag tatggtttcc tttagagaaa
     6601 tcatcgaagc acaaccaaac cacccagata aattactaga agtaccttta ggacgtgatg
     6661 tttctggacg ggtacaaacg gctgatcttt cgaagatgcc tcacttactc gtggctggtt
     6721 cgactggtag tgggaagtca gtagcaatta atgggattat cacaagtata ttaatgcgtg
     6781 ctaagcccca tgaagtaaaa ctgatgatga tcgatccgaa aatggttgaa ttgaatatgt
     6841 acaacggcat acctcatctg ttgacgccgg tcgtgacgaa ccctagaaaa gcagcgcaag
     6901 ccttacaaaa agtagtacaa gaaatggaag aacgatatga aaaattcgcg gcaaccggag
     6961 taagaaatat ttctggttac aatgaatttg ttcaacagaa aaacttggaa aacggaacga
     7021 aacatccaac cttaccattc atcgtagtga tcgtagatga attagctgat ttgatgatgg
     7081 tagccagcaa tgaagttgaa gatgcgatta ttcgtttagc gcaaatggct cgggcagcgg
     7141 ggattcatat gatcctagct actcaacgtc caagtgtgga tgttatcaca ggaatcatca
     7201 aagcaaatgt accttccaga atggcatttg cggtatcaag cggtacagat tctcggacga
     7261 tcattgattc taatggggca gaaaagctct tagggcgagg agatatgcta ttcttgccaa
     7321 tgggtgagaa taaaccgatc cgtgtgcaag gagcattcat ttctgaccac gaagtagaac
     7381 gggtcgttca atttgttaca gatcagcaag aagctcatta tgaagagaaa atgatgccga
     7441 cagatgaagt tgaaacgaca ggtgctccag aacagccaca agatgagctg tttgaagaag
     7501 caaaagcact tgtcgttgaa atgcaaacgg caagtatttc ccttctccaa agaagatttc
     7561 ggatcggtta caaccgagca gcacgtttag tagatgaact ggaagctcat ggagttgttg
     7621 gcccgtcaga aggaagcaag cctcggaaag tattcattga gcaggaagaa acatcagaaa
     7681 cgttgccgga cgataatgac atgtaaaact tgtgtgatga agggttgaaa aacgaataac
     7741 caataaaaag acaaggcatg atgataccaa aagaaaaaat ggtttttttc catcttttct
     7801 aatacggtat gatgtcttgt ctttttagtt tttgtgagat taaagttcta ttcgatttat
     7861 ttgtgaagta ttgcattaag gaaatgaatc atgtatagta tgtagcgaaa ctttgagaaa
     7921 aagagggaaa atactttgga aaaacagtcc atttatggct tgacgaatga agaattaatc
     7981 aattggttta tagaaaacgg cgagaaaaaa ttccgagctg cccaagtttg ggaatggttg
     8041 tatcaaaaac gtgtaagtaa tttcacagaa atgacgaatc tatcgaaaca attgatcgaa
     8101 aaattatcgg agcattttat catcaatcct ctaaaacaga tggtcgtcca agaagcttcg
     8161 gatggtacag taaaatattt gtttgaactc cctgataaaa acatgattga gactgtactg
     8221 atgagacaag aatatggctt gtcagtttgt gtgacgacac aagtaggatg taatatcggc
     8281 tgtacgtttt gtgcaagcgg gctgctcaaa aagaaccgtg atctgactgc tggagaaatt
     8341 gttgcacaga tcatgatggt ccaacattat tttgatgagc gcaatcttgg cgaacgcgtt
     8401 tcacatgtcg ttgtaatggg gatcggtgag ccatttgata attacgacaa tgtaatggac
     8461 tttttgcata tcatcaatga tgccaaagga ttggcaattg gtgctcggca cattacagtt
     8521 tccactagtg gattagcaca caaaatcaag gaattcgcta ataacggctt gcaagtcaat
     8581 ctggctattt ccttgcacgc gccgaataat gaggtgcgaa catcgatcat gcggatcaac
     8641 cgaagtttcc caattgagaa attgatggaa gctgtggatg agtatttaga gaaaacaaac
     8701 cgtcgaatca cgtttgaata tatcatgttg aatcaagtaa atgatagacc agagcatgcg
     8761 caacaattag cagatctatt aaaagataag aaaaaattag catatgtcaa cttgattcca
     8821 tataatccag tcagtgaaca tgatcaatat tctcgcagtc caaaagctga tgtattgaga
     8881 ttttatgatg tattgaagaa aaacggcgta aactgtgtga tacgtaaaga acatggtaca
     8941 gatattgatg cagcttgcgg acaattgcga agcaagcaaa tgaaaaaaac agttgccaaa
     9001 taatcgtatc ctactcgttt tttcaattac cataaaagga gcagttttct taattaagga
     9061 actgttcaac ttaaataaga gaaaagattc tatagcgaaa gctataaagc tttttttgac
     9121 aagaaaaacc ctcatcaagc aaagaaatgt cctcaatttg atgacagcct gcttgatggg
     9181 ggttttagca attatttaac tgattttctt atatccttgc tggctttctt gtgtagcatg
     9241 ataagtttct acgtcaagaa tggcctgttt aaatttttct cgggtgattt cataaggcac
     9301 atgtttaata tcatttgttg ccatggcttt atctaagatt gcttctaaat cggtcgtgac
     9361 attgagattc atgtcggtta acgatactgg aagttggttc tttttcataa acacatagat
     9421 tttatcaaac aaatcgaact gctgatccat catcaataag gtcagtacac cataactgac
     9481 agatgctccg tgaaggtatc cctccatttt ttctagaaca gtcgtaccgt aatagaatga
     9541 gtgtgccata gcagaattat agttattgtt aactaaaaca gaaaccaatc cggtagtaac
     9601 aatgatatcc gaaacgactt gttcaattgc atatgaggga cgatcgtcgg cactatcttt
     9661 caatgcttgc gtaccataag tcaagagacg atcaatgcac atttttccga tttggattcc
     9721 taatctatcc gtgtagccta gatcatcgcc acgagcagaa aaagtagatt cgacttcttt
     9781 ggataaagca tcgccaatac ctgcccataa gtatttatca ggtgcttcgg caataattgc
     9841 tgtatcaatg aaggtgtgta caggtggttt tgaaggaaag aagagtccgt ccattacgcc
     9901 ttcttcgtta tagatgacac ataccgcagt gacgggcgaa cagttcgaac caatagtggg
     9961 aaaggtgaag actggtttag ctagtttttc accaatgact tttacagtat cgcaagcacg
    10021 gccaccaccg actgcaaaca ggacgtctgc tttttggaca ctttcatgct ggatcaactg
    10081 ttcaatattt ccataagttg aattaccccc gtaccagaga ctggcgacaa cctctatttc
    10141 ctgtgtcaaa gctactttta ttttgttttc tgcctttgaa agtgcagtct tccctccaat
    10201 cagcactact tttgtcccat attctttgac gattccattt gctttttcat acgcatctgt
    10261 tccaatggta taatttggta agaaaacact ttgactcata ttcatttcct tctttcttcg
    10321 ttgaaacggg ttaaaatttt aaagagtgat cgatctgact gcggctgtag atggagtaga
    10381 ggtgaaccta agacaggata agtgatgaat aaggtggcat gaacaccttg aaatcatcaa
    10441 taagtatcct aaaaacgaac aagtacaaaa acattgaaaa cgacaataat gaatttttgt
    10501 tcctcttagt atttctaccg attccctttg cttttttgta attatctaaa aattctaaaa
    10561 attaagatta ttatatgaaa acaggtttta tttgtcaatt cataattggt tttttttaaa
    10621 gcaaaagata atctatatca tgatgaacaa acagagtttt ttcctccaat tgatggcttt
    10681 cctgatcttt cctattttga ataaagtgtt tctgtataat tttttatttt ataagtaaga
    10741 taaataatga aagaatagag atactgattg gtagctaaag atttttgagc gagaacattt
    10801 cgttttttca aaaggactgt tagaataagc aagaacaagg gggaagacgt atgataatca
    10861 gtgaatttga ccgtaataat ccagtattga aagatcagct ttctgattta ctgagactga
    10921 cttggccgga agaatatgga gacagctcgg cagaagaagt agaagaaatg atgaatccag
    10981 aacgaatcgc ggtagcagcg gtagaccaag atgagttagt aggatttatt ggtgcaatcc
    11041 ctcaatacgg tatcacaggt tgggaattgc atccattagt tgtagaaagc tcccgacgaa
    11101 agaaccaaat aggtactcga ttagtcaatt acttagaaaa agaagtagct tccagaggag
    11161 gaatcacgat ttatttaggt acggatgatt tagaccatgg aacaacgtta agtcaaacgg
    11221 acctgtatga gcatacattt gataaagtgg cttccatcca gaaccttcgt gaacatccgt
    11281 atgaattcta tgaaaaatta ggttataaaa tcgtaggtgt cttaccaaat gcaaatggct
    11341 gggacaaacc ggatatttgg atggcaaaaa cgattattcc tcgaccaaat tctcaataat
    11401 aaaaagaggt tgtgacagaa gtaatcagct tcaagaaata agaaggaatt tacgaaaatt
    11461 acttcttgaa tttttgtgaa attccaactt atttccgaag aagctacttt tggaacaccg
    11521 tgtaccagag gttgtgaaaa agtcgcttag tttcgagtag taagaaaaat tttgtgaaaa
    11581 tggctttcta catttttgca
//
LOCUS       DAMEEU010000084        11584 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.085, whole genome shotgun sequence.
ACCESSION   DAMEEU010000084 DAMEEU010000000
VERSION     DAMEEU010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.085"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(115..1245)
                     /locus_tag="PB779_002385"
     CDS             complement(115..1245)
                     /locus_tag="PB779_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDE0739890.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYRLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            complement(1786..1992)
                     /locus_tag="PB779_002386"
     CDS             complement(1786..1992)
                     /locus_tag="PB779_002386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739891.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            complement(2008..2622)
                     /locus_tag="PB779_002387"
     CDS             complement(2008..2622)
                     /locus_tag="PB779_002387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HDE0739892.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            complement(2769..3452)
                     /locus_tag="PB779_002388"
     CDS             complement(2769..3452)
                     /locus_tag="PB779_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDE0739893.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            complement(3561..4019)
                     /locus_tag="PB779_002389"
     CDS             complement(3561..4019)
                     /locus_tag="PB779_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HDE0739894.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            complement(4103..5866)
                     /locus_tag="PB779_002390"
     CDS             complement(4103..5866)
                     /locus_tag="PB779_002390"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HDE0739895.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            complement(6087..7547)
                     /locus_tag="PB779_002391"
     CDS             complement(6087..7547)
                     /locus_tag="PB779_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739896.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIRGIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            complement(7755..8681)
                     /gene="glsA"
                     /locus_tag="PB779_002392"
     CDS             complement(7755..8681)
                     /gene="glsA"
                     /locus_tag="PB779_002392"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HDE0739897.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            complement(8704..10131)
                     /locus_tag="PB779_002393"
     CDS             complement(8704..10131)
                     /locus_tag="PB779_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0739898.1"
                     /translation="MQQSKTKIPAKKLTFFGFLAMTISMVVSLYEYPTFATSGFSLVF
                     FLLLGGLLWFIPVALCAAEMATVKGWEKGGVYTWVSRTLGKRFGFAAIFFQWFEITVG
                     YLTMLYFLTGALSYATGIGAIQNNKYLKLAILLIIFWAILLSQLKGTKYTSLIARIGF
                     VAGILLPALVLFGLGIHYVASGAPLQTILSMKTLIPDFSKLPTLVVFVSFILAYMGVE
                     TSASHANEMENPKKDYPLAMFVLVILAIILDTFGGLTVATTVPQHGLSLNTGVIQSLE
                     FLLRHIDPNLAWIAKILAILVCLGVIGEIASWVTSPSKALHVAAEEGLLPEYFAKENT
                     HGVPAHLMIANGIVATIWAAVFTLSGGGNNLSFLAAMSLTVVIYLMLYFMFFAGYLKL
                     VFKDDSLERAYQVPGGKVVKVIVACLGLLTSLFAFCISFVPPASIAAGQHGIYETILI
                     VSYLIVLVIPFTIYACRHKFQHAEK"
     gene            complement(10162..11376)
                     /locus_tag="PB779_002394"
     CDS             complement(10162..11376)
                     /locus_tag="PB779_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HDE0739899.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         3505 a         2403 c         1912 g         3764 t
ORIGIN      
        1 atgatttttt gagatacttt cattgcgaat tcctctttct aaaagaacct ctcgcttgaa
       61 aaataaaaga ttgtacttta tgataattca aactgagagt ttctcagttt ctctttattg
      121 tttttcaggt cgatagagcg ccaactcttc ggcctgtatc tttgaagaaa tattcaacgt
      181 gattccgatt cctaaagaaa ggatcagata acttgttcct ccgtagctaa caaatggcaa
      241 tggcacacca gtcattggca tcagccccgc gatacttccc acgttcatta tcgtctgaac
      301 gaatagcaaa gttccgaatc ctaaaagaaa caatccagct tgctgatttt tacagcgact
      361 gcttaaacaa aagattctca tgcataatga gaacaataag aaaagcacac acaatgcacc
      421 gattagccca agctcttctg taataatcga aaaaataaaa tctgtttctg tctctggaag
      481 ataccctttt tttgtgatac tatttcctaa tccccgccca aatatgccac cattatatag
      541 tgcataaaac gaatgggtca tttgatagcc cgcaccatga ctatcgataa aagaatctct
      601 taaagtcgcg atcctttcat aagcatgatt aaacatctgt ggaagccaac ctttatttcc
      661 taaatataat accccgcctg ctgctccaat cagcaatgca gaaaaagtaa cgattagata
      721 gatccctttt ttaaatggaa ccgccgctgc ccaaaatatg acccacgcaa tcgaaaggat
      781 catcaatgct ccagcaatct ttggctgaaa taaaatcaga aaagttatac ctactgtaat
      841 caggaatggt ttttttagat cttttgggct actatttccg tcacgaaaaa accagcttaa
      901 ataaaaaatc aaaaaaagat ttgccagttc agaaggctgg aattgaatgc caaacagaga
      961 gatccaacgt tgtgcgccgt tgacagtgac accgaatatc cctattctta ctaatactaa
     1021 aaagaaaatc gataaggcta aaccgtatcc tgctatttta gggtgaagta aatagtgtag
     1081 tttgactgaa cgagctaaga agatcacgct ccaactcaaa aatatgaaaa ttagttgacg
     1141 caataataga ctttttgtat tttcatcggc ttgcaataaa cgataagaac tggcactgta
     1201 tacttctaaa agaccgatca tggacaaagt caaataagga cccaaaatcc accaatcgat
     1261 cttttttcac cgcatctcct cctcacacag caatccactt gtcaggtgag gagcgagttt
     1321 gtctcatcaa ataagtcagt cacaaaaata taaagaaaag gtcagaaacc ttttcgaaca
     1381 agaattctga cctagcatca tctcatcgtc cgagttttag cactatacaa cgtaaagaaa
     1441 acattcttag ctattggaaa aagccttaat ccaacagttt ctgttttacc cattggcgac
     1501 tttcgacgtt tctgggcaac agcctatgtt tgtataggag cctcacctaa caaggttatt
     1561 actatattct atttacgagt tcatgataga cttttcctaa tgattaggca atggaatttg
     1621 aaatgaaata gtgaaattta acaatcttta atatttttta gaaaaaaata acaaataagt
     1681 tgaaagaatc ccgttgcaaa ttctttcagt tgcaccagga ttctttgaaa attttttagt
     1741 tttatgtgtt tttttatatg ttttttcact tttcggaata aatatttatt tgttaaagta
     1801 attaaacaat ccgctaatcg tttgatctgg catttctatt tccttaccat ctaaagtaac
     1861 agtagtaacg acaaaatggt cttgcaatgg cggaacttct aagtactgcc cttgcagaaa
     1921 atcattcact gtttcatatt cttttttcat ttcttttgaa tctgtcgatg gtttatagct
     1981 tatttttaac ataactagtg ctccttttta ttcgggacgt gcaatcgtga aaatttctcc
     2041 tattgctgca taatcatttc ctgccaaacg gcttacagca ttcaattttc ttggatcgat
     2101 ccttcctgtc ttatcatcat agactgtttc atttaaatga tatttctgta cttctagcaa
     2161 aaataaatca gctgttactt tatttttatt ccgtatctcg acatgttcat ataaggatgt
     2221 ttcaaaacga acttttgctt ctgtcaatgc tggtactgaa atgattactg aatcagttaa
     2281 agtcaagtca gtcaggtaca gttcgctttc ctcattaggc agattggctg ctgttttatt
     2341 tacttcttct acgttgtcct catcaaggat atggataaca gcttctcttg tctcaagaat
     2401 attctttgct gtgtctttta ctgcatcttg ttttctctgg atcgccaagg ataagatggg
     2461 tcgattcgaa ctgacgatat tgaagtaact gaagggtgcg atattcacta tatcttttgc
     2521 tgatttagtc gttactactg ctactggtct agggatgact gaaccaatca gcaacttgta
     2581 attttcacgt tctgtcaatt ctgaaggact ccgttcaaac atggtttcgc cttctttcta
     2641 taaaattcgt taaaaagcag atcttgaaga caaaatgaaa agtaatgctt ttttcatctt
     2701 cttagaatct gctttaaact atctatcaat ttttcttttt tgtcaagaat ctgtgccgtg
     2761 cgtgtttttt agttatttgc tttacttgcg gcttcgacat atcttttagt gatcaattgc
     2821 ggacgggtga taatagatcc aactacgact gaaaaagcac ctaattcata tgctttctct
     2881 acttgttcag gagagtcagt atgtccttcc ataattactg ggatatcgac ttgttctatg
     2941 atttgattca ataaatcaaa atcaggtgtc tgcgtctttc gtgaatattc tgtatagcct
     3001 gctaaagtcg tagacaaaag atcaaaacca tcttcttgcg cttgaagcgc ttcctcaaaa
     3061 gtcgaaatat ctgccatagc taaccgaccg tgttcgtgaa tcatttggac aagttcagca
     3121 gttgtttttt ctgtcggacg tttacgagaa gttgcatcca gtgcaatgat ttctgcttgc
     3181 gtctccaaaa gttcttccac ttctttttct gtcgcagtaa taaacacttc tgacccatcg
     3241 taatctcttt tgataatccc tattaccggt aaatcaacga ttcgcttgat ttcattgata
     3301 tcttctgtcg tatttgctcg aataccaact gctccgcctt cttttgcagc caaagccatt
     3361 ctccccataa taaaagaact gtgtagcggc tcgttttcca aagcttgaca agaaacgacg
     3421 actccgcctt tgatttgttc cagtgtatcc acaatatctc ctccagtaat gttatataaa
     3481 aatacagctt catataaaaa tgtaaccctt ttctattcag gagacaataa tgagctattt
     3541 ctttcagcag acctttctta ctaaaagaaa attacttcaa attcttcgta tacgaccagc
     3601 ttctcttctg taaattctat gttcaacgct tctttataag catgtttaaa aaactcagca
     3661 tggactttcc gccaataagc taatgtccga tccccttctc cttctttcca agcatgctct
     3721 ttcgtgactt cactaaaagg caagatggtc acatttatat ttttgatgat acaaactggt
     3781 tcattttttc cattcaggac cacgtctaat tgaccaactt ttggtaaagg ctcattctct
     3841 tgtttataca gatcgtaacc acttgatgta ccagtcttta tcttttttac aactagttcg
     3901 ctcaactcgt ctgccatttt ttctgtatcc ccaaatgaaa agaaacctaa tttttctgat
     3961 tgataactag gatatttttc ttggaacttt ttgacatatt cttctacttg ctgatacata
     4021 acatccaccc ctttgctttt tataatgaaa aaaccatcca gatactagta taaacaatta
     4081 tctggatggt gagcataatg aattattgaa tattcaagac acgcagacta tcttcaacga
     4141 tttgttttgg tgttaaatga taacgttcat aaagctgccc tacaggaacg ctatccgtga
     4201 attctttctc tgcaccaaaa tttaatacgt tcattgaaga atcaccataa taacgactga
     4261 tattttcgcc aaatcctcct gacaaactac catcttctaa tgtgatgact aattcgtgtg
     4321 tttcttttaa tttatctaat gtttctacgt cattttctgt gatcgttcct ggattgatca
     4381 acgttgcttc gattcctttt tttctaaaag cttttactgt ttcttttcct aattcaagaa
     4441 aaccgcctaa agctaaaatt gctacttttc ctccattatt tactgtttga taggctggaa
     4501 tactataatc atttgcgata gctgtaccat gttctacacc atgtgtagga attcggattg
     4561 ctacaggctg cgctgtttgt tcgaacgccc aatctagcat agagatcata tcctcttttg
     4621 ttgctggagc aagatatttg atgttcggga tacttgataa gtaaggaatg tcaaatgttc
     4681 cttggtgtgt tcggtcacta gctgagatcg ttccgccacc gactaaaata atcactggat
     4741 tctcgttgat cgctaaatca tgtgataatt gatcatatgc ccgttgcaag aaagtacttg
     4801 attggaagac gactggacgt actccctgag aagccaaagc agaagcgaaa gtgatagagt
     4861 gctgttcagc gatccccacg tcaaaataat gatctggatg tttttcttgg aatgttttca
     4921 gtccaaaggc gcctggtatc gctgcattga ctgcggcaat aggagctgta cttgtttgca
     4981 ttttcttatc caaataatcc atgatgatca tattaaatgt ttctccagaa gttacttgct
     5041 ttgcctcccc ggtggacaga tcaaatggta catgccaatg atatttcatt ttattatcga
     5101 ttgccggctg ataaccgcga cctttttccg tatggacgtg aagtacaatc ggatgatcaa
     5161 tatcttttac ttcttcaaat aaacggatca ccgtttccag atcgtttcca ttatccacgt
     5221 aacgataatc aaatcccatt gctttaaata ggttattgct gcttttaccg ttggtttgac
     5281 gaagctcagc taagttttta tataaactgc catgattctc atcaatagac atctcattat
     5341 cgtttactaa tacgattaga ttggattgta aaacaccacc attgttcaat ccttcaaaag
     5401 ctaagccacc acttagggag ccgtcaccga taaatgctac cacatttcct gattctttct
     5461 tcagatctct cgctttagct aaacctgttg ctaagctgat agatgtagat gtgtgcccca
     5521 ctgtaaaata gtcatgttta ctttcatgtt ggttggaata tccgctcact tcacggtaat
     5581 gtcctttttc aaaaccattt tttcgaccag ttaaaagctt atgaccataa gactgatggg
     5641 aaacatccca aacgatttta tcctttggtg aatcaaatac ataatgaaac gcaatcgtta
     5701 attctactac acctagattc ggaccaacgt gcccacctac atcgctgtcc ttttgcaaga
     5761 ttttttggcg catctcttct gccaactgtt tcatttcctc aacagataat tttttgacat
     5821 ctgcggggct attgattgca tccaatacat gtaatactgt actcataata cattctctcc
     5881 tccgtactat cttcttttaa tgaaaataga tttgttacac tttatctatt ctactactta
     5941 gagttgactc taagtcaata gcattttaaa aaaatttcag agaaagcttg ttatataagt
     6001 agatcttcgc acgaatcagg actcaaataa aaaccttcta cagacaatta aaaagctttg
     6061 tagaaggtct cctaattaag gtctcatcaa gaaatatgtt tttttaatag gtgaagttcc
     6121 tgagcaatat gatacaaatg gatgtttgca ccttttaatg agattggata gatctttgtc
     6181 ttttcagttt ctaatccatt ttgatagcta gcagcatcgc acaaaaccac tctttttttc
     6241 gcacatagac attcatcagg caattcttct aatgaacgaa ataaaatagg atttatttca
     6301 gcgatgcctt cttccgcata caaatgaaat tgggttcgat aaaaaaattg tttgactgaa
     6361 ctttctgaaa caacaaaaat ttctatttcc tgtctccccg cttgttcact gttgatcaaa
     6421 gaaagacttt tgacgaattt tcgaatgaaa ttttcattcc atcttagttg gatttgattt
     6481 ttctttttcc actcttccaa tatttctaca atttttccgt acagaagttg ttctttttct
     6541 gatagaagat agatcctttc cggtaaaaat acttgtccat ctgcccacaa cgtacggaca
     6601 aattgtaaaa aggattgctt gaaaataaaa ttttctgcat cgtcgatttc agcgatacta
     6661 ataatctgta aaatcaattc attcagtgat aggtcattga gaacaaaatt tttataaaca
     6721 acttcgaaat cttttcttaa cagctccatg ttctcattgg tataatttct actgttgaac
     6781 aaagaaaaaa tataatagac atcttcttct tgtaagtcta gaattccttt ttgctcttcc
     6841 aatccttgac agactaattg aaataacggc ttcgtttctg cgcttttctt atcttcttct
     6901 ttcagtccaa ggggaaatgc ctttcttccg attgcgatct ctattcctcg tatgataaag
     6961 gacttttcat cttccgaata tcttctttta aaaaaatgag tctctacata atcaatcaac
     7021 tcgttacaag cttcttctac atacggattt ttattttcat agccttccca attgacataa
     7081 cgtactaaag ctagcaagat gttccgcgag tcaaattctg ggataatgat ttctttattt
     7141 ttcaaataat cattttcttt aaaaaaatcc aatacgattt ttttgattgt atatactttg
     7201 ctcaaagaaa taaattcaag atcagccagt tctgtactcg tgaatatacc attaaaataa
     7261 taacttaaaa actttaaaaa ataagattga ccgtacagaa actgtgtgag ctcagaaaga
     7321 gcaataccat gtttgaatac gagtttatac ttatgcttct ctcttacttg ttcttttata
     7381 caatattcta gacactcggc tagactttct agatcgtgaa ggatcgttgg tgtagtcacc
     7441 cttagagaaa tagctgtttg ttcgatgtct atttcttgga attcaaataa ttgttcacac
     7501 agatacactt ttctaaatat atttcgctcg atgtaatttt ccagcattcc tgatacacgc
     7561 ctccagtttt tcttatgatt ttatttaatc atatctgtaa atcgtatttt tgtttccttt
     7621 ttatttagaa aagccctttc aaaaaccaat aaaaaaagaa actgggacaa aagtcaaaca
     7681 agctcacaat ttcagcctca ttgtaggtag ctttgagccg tttggacttt taccccagcc
     7741 tctttcaaga atggttattc aaagatgtca gcgtctagtt ctttgactac atctttcaac
     7801 aattggatac cagctgcgct gttaccaaat ggatctagtg ccgggctgaa gacacctatg
     7861 ccgtaacgat ttggcacagc tgccatcaac ccgccgccta caccgctttt tgcaggtaca
     7921 ccaacatgga cggaaaactc tcctgattca tcatacaaac cagcagttgt cataattgat
     7981 ttgacgattg tagcactttc ttcagtaatg atttgtttgc cattccaagg agcaattcct
     8041 ttatttgcca gcacagcagc taattttgct atgcctgtag cggtgacatt gagggagcat
     8101 tgtctgaaat aagcatcgag tatctccggt acgtctcctt cgatcatttg attacctttc
     8161 atatagtaag caagagagcg attgatatca cctgttcttg attcagaatg atagatttct
     8221 tcattcaatg tgatattagg atcatcacag atctctttca taaatgacaa gattcgctca
     8281 aatttttcat ctgcatcttt accggcaatc aacgaggttg ttgcaatcgc tcctgcatta
     8341 acaaaaggat tcattggatg tttgcgatga ttgatttcca tattcatgat agaattgaag
     8401 gcaaaaccgg ttggttccgt gttgattgtt tgaaagactt tttctattcc gttgtctttg
     8461 attgctaata acaatacggg aacttttgac atgctttcga tggcaaagcg cacatcggcg
     8521 tctcctccct caatcagttg ttttgtatcc aaatcataaa tcgccatacc taattgtttg
     8581 ggatccactt cagctaatgc tggaatgtaa tccgccactt gtcctgtttg ataatagtgg
     8641 aaattttttc caatcaattg ttctaattct tttacttcca tttgaataac cagctttcat
     8701 tttttatttt tctgcatgct ggaatttatg acggcatgcg tagatcgtaa atggaataac
     8761 taagacgata agataagaaa caatcagaat cgtttcataa atcccatgct gtccagctgc
     8821 gatactagca ggtggaacaa atgagataca aaaagcaaaa agtgaagtca aaagacctaa
     8881 acaagcaacg attactttta caacttttcc gcctggaacc tgataggctc tttcaagact
     8941 gtcatcttta aaaaccagct tcaaatagcc cgcgaaaaac ataaagtaca acatcaggta
     9001 gattacaaca gtcaatgaca tcgctgcaag aaatgaaaga ttattccccc cgccgcttaa
     9061 tgtaaagacg gctgcccaga ttgttgcaac gatcccattt gcgatcatca aatgagcagg
     9121 aacaccgtgt gtgttttctt ttgcaaaata ttcaggaagt aatccttctt ctgctgctac
     9181 gtgaagtgct tttgaaggag aggttaccca agaagcaatt tctccgatga cacctaaaca
     9241 aacaagaatc gcaagaattt tcgcaatcca tgcaagattt ggatcaatgt gtcttaatag
     9301 gaattctaac gattgaatca cccctgtatt aagagacaaa ccatgttgag gtactgtagt
     9361 agcgacggtc aatccgccaa aagtatctaa aatgattgcc agaataacca atacaaacat
     9421 tgctaatgga taatcctttt tagggttttc catttcattt gcatgactgg cagatgtttc
     9481 tacgcccata tatgctaaaa taaaggaaac aaaaacaacc agcgtaggca atttcgaaaa
     9541 atcaggaatc aatgttttca tagacagtat cgtttgtagt ggagcgcctg aagcgacata
     9601 atggatccct aagccaaaca agactaatgc tggcaacaag ataccagcta caaaaccgat
     9661 ccgagcaatc aatgaagtgt atttggttcc ttttaactgt gagagtaaaa tagcccagaa
     9721 aataatcaat aggattgcca atttcagata tttattgttt tgtatagcac caatacccgt
     9781 tgcataggat aatgcaccag ttaagaaata cagcatggtc aagtagccaa ctgttatctc
     9841 aaaccattgg aaaaagattg cggcaaaacc gaatcgtttt cccaatgtgc gactgaccca
     9901 agtatagaca ccgccttttt cccatccttt caccgttgcc atctctgctg cgcacaatgc
     9961 cacagggata aaccatagca aaccgcctaa taacaagaaa aatactaagc tgaagcctga
    10021 ggtcgcgaat gtgggatatt catataatga aacgaccatt gagatggtca tagccaaaaa
    10081 gccaaagaac gttaattttt ttgcaggaat tttcgttttg ctttgttgca tgaatcttcc
    10141 tcttttctat ttgaatttgt ttcaattgag tttgttgcca aagaagaaaa agtccaatcc
    10201 ttcttcttgt tcttcttttg tagtagtgat cgttgtaaag tgcatcgccg attttaaaat
    10261 cactgttgtc agcacatagg catacacggc agtaatgatg acaccaatca cttgaatccc
    10321 taagaagtac cagctgcttg gattcgttag taaatggctg ttagatgcaa agatccctat
    10381 cagaatcgta cctgtgaatc cgcccatgcc atgaacaccc cacacatcaa gtgcatcatc
    10441 ccattgtttc tttttacgaa aatcaacagc agcatgacag acgatacccg caatgatccc
    10501 aatcagcatg gcactttttg cttctacata accggcacaa ggcgtaatgg ctgccaatcc
    10561 agcaacggat cctgttagta cgtcgacaaa atcaaagcca tttcctttta cttttgcaat
    10621 gatcagccaa gtaatcatcg caaatgcaag agcgatgaat gttgaaccaa atgcattgac
    10681 tgcttgttca tctgctcgaa gtgcaccacc ggaattaaaa ccgaaccagc caaaccaaag
    10741 cagtcctgta ccgatagcag ctgccataag actgctatgc tgacttcttt ctcctaaagg
    10801 aatctttctt tgaccaagtg tgaggataca tgctaaagag ccgaatccag ctgtcgtgtg
    10861 gatgactgct ccaccagcga aatctctaaa tcccatctga tccaaaaatc cgccacccca
    10921 tatccagtgg caaacaggga aataaatcag cagattccaa aaaataacaa gtataatata
    10981 gccttttaaa ttcaatctcc ctgcaaaagc tcctgtcatc aaaggaacgg taatcacgat
    11041 aaacatcagt tggtaaagaa agaacattaa aaatggaatc gttgcaccat gaaacatgtt
    11101 ggggaagctt gtaacatgtc tcatcaaaaa gaaatctgcc gggtttccaa taacaccgcc
    11161 gatatcccgt ccaaaggcca atccgaatcc accaaatacc cacataatcg ttgttatccc
    11221 aacggagaga aaagattgag acatgatcgt tagtatatta ttcttccgtg ctaatccgcc
    11281 gtaaaaaaaa gctagaccag gagtcatcag gcaaaccatt gctgtacata aaatcatgaa
    11341 tgctgtatct cctgtattga taggtaatgt attcattttt ttcgcctcct ttctacgatt
    11401 acgagtataa aagaaggtgt agttgttttt ttcttctgtt tttttgaatt aatacttgca
    11461 tttataaaag acagacaatt aataaaagct tgatgtgttg tgctcttttt cgtttttcac
    11521 acaaataaag acaaaaaata aacggtcttc tttttataga aaaccgttta ttttcgtctt
    11581 tttt
//
LOCUS       DAMEEU010000085        11478 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.086, whole genome shotgun sequence.
ACCESSION   DAMEEU010000085 DAMEEU010000000
VERSION     DAMEEU010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11478)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11478)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11478
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.086"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..255)
                     /locus_tag="PB779_002395"
     CDS             complement(<1..255)
                     /locus_tag="PB779_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739900.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKL"
     gene            549..1364
                     /gene="thiD"
                     /locus_tag="PB779_002396"
     CDS             549..1364
                     /gene="thiD"
                     /locus_tag="PB779_002396"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HDE0739901.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(1693..3144)
                     /gene="cls"
                     /locus_tag="PB779_002397"
     CDS             complement(1693..3144)
                     /gene="cls"
                     /locus_tag="PB779_002397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HDE0739902.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            3485..6151
                     /locus_tag="PB779_002398"
     CDS             3485..6151
                     /locus_tag="PB779_002398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HDE0739903.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            6515..7267
                     /locus_tag="PB779_002399"
     CDS             6515..7267
                     /locus_tag="PB779_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HDE0739904.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(7289..8443)
                     /locus_tag="PB779_002400"
     CDS             complement(7289..8443)
                     /locus_tag="PB779_002400"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HDE0739905.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYSLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            8628..11069
                     /locus_tag="PB779_002401"
     CDS             8628..11069
                     /locus_tag="PB779_002401"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HDE0739906.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(11226..>11478)
                     /locus_tag="PB779_002402"
     CDS             complement(11226..>11478)
                     /locus_tag="PB779_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0739907.1"
                     /translation="TEGFQETLKTISSTLPQSFKKKFTIFHRYQSGISNAFKVPHSNG
                     VTEGLNNKIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
BASE COUNT         3705 a         2029 c         2440 g         3304 t
ORIGIN      
        1 gagtttatga cttcttggaa attctttttc aatcagtttt ttcatctgtt tatgaaattc
       61 ttttttttca gtaaacataa aggtttgggt atcgtaacct tcttcatgta ggaaatagat
      121 tattcctttt tctgtgtttt gcgtataagc ttttatactc ctgtcttttt tgaaagaaca
      181 gatcgtatag ccatctattt ggtctggtag tcgtttgatt ttcttcaaaa tgactttttt
      241 atcctcaagt ttcatttttt tcacctgact ttattttttt catatggaaa tcatagcgcc
      301 tttggttata tgaaaacaag aaggatactg aaatatatat aaatcaaata gtggttattt
      361 attattagaa tagcgaatac aaataaacga ccactatttt ctgatttatt gcaaatgttt
      421 tttcaaataa atttgattac caagaaaagg tagtggtata tttactgagg gatactttga
      481 aaaacatatg atagaaacag taacagtatt atgaaaaatc tttttataaa aatggaggaa
      541 tcgatttgat ggaagatcag tatgtacaag caatgacgat cgcaggatca gatagcgatg
      601 gaagcgcagg gatgcaagca gatatgcata cattctttac aagaaatgtt tacggtgttt
      661 ctgtcatgac cgcatgtgtt gcaggtaatt cttacggaat cggagcaagt gtgacattgc
      721 caacagattt tatcgacaaa gaatttgaac tgattgcgaa ggactttcaa atacgtgcag
      781 ctaaaacagg tatgctagca gattcaaagt tgattgagac agttgtaaaa aattaccaaa
      841 aatatgattt tggaccatta gtcgtggatc ccgtaatcgt aacgaaacat ggaaatcttt
      901 tactagaaga atctgctttg caaagcttga aagaaaagct tgtccctttg gccgaagtac
      961 tgacacctaa tttttatgaa gcagaaaagc tgactggacg gacattagca gctgaagaag
     1021 attttgtgca agcagcaaaa gaactgcaag atatgggtgc aaaaaacgtt atgatcaaag
     1081 gacatcatgc taaaaatgcg cagcaagaaa cagtcaatga ctacgtattg ttcgaatcag
     1141 gaaaatcatt ttggttaaat gcaccatttt atcctaccga ccggatcaac ggaactggcg
     1201 attcgctatc tgcatgtatt gcagctgagt tagcgaaagg aaaaacagtt gaacaagcga
     1261 tccgattggc aaaagactat gtaaaccgtg caattcgtga agaaataaat gtagggcaca
     1321 aatatggccc catcaatcat tgggcagctg gtgaattaga gtaaaagaaa gaagttgtga
     1381 aaaagttgcc ctgcatcaag taataagaac agccaagtaa aaacagcttc ttatgttttt
     1441 aacttggttg gacttattac cgcagatgca agcttttgaa caccgtttaa gaaagaggtc
     1501 gtgagcctgc cgtccagctc cgagtcacaa ggaacaagtt caaaaaacag cttctcatgt
     1561 ttgttgaata ttgtgacttg tgaccgagga gttggcagga gaacaccgtt tgttcggaag
     1621 aagggactgt gacaagattt ttgtcacagt ccctttaatc ttagtatatt tttctctact
     1681 tgaataaaaa aattatagga ttggagaaaa taatcgagaa atttgttgct tgaataatag
     1741 ccagttagac atttccttga ctgtttcagt tgtcatggat gaacaatgtg tctcatcttc
     1801 tttgaactga gtagcaagtt cttctaaaaa ctcaggatcg taaatgacag cacttgtttc
     1861 aaaattcaat cggtagctac gaatatcttg atttgctgaa cctaccatgc agatttcatc
     1921 atccattatc aatgtttttg catggaggaa gccgttctca tagacaagga tttgtacatt
     1981 ttccttgatc agctgccgag cataatattg tgttgctcga taaataaaag gatgatccgg
     2041 tttgttggga atcatgattt tcacatctac accagaggca gttgcgattt ttaaagcagc
     2101 aatgacactt tcatcaggaa caaggtaagg tgtctgtatc caaacacgtt ttttagcaga
     2161 agtaatcaat ttgataaatg aaagcttgat ttgttccctt tcgttattcg gtccgcttga
     2221 aacaagctgg atggatgtat cagcaagctt agattcatct cgatctgctt ttttaaagaa
     2281 ataattcaaa tgatagccga cctttttttc ttcaggtacc gagacgttcc agtctgttaa
     2341 gaagcgaagc tggagcaaag aagaagcggc accgaaaatc cgtatatgcg tatcgcgcca
     2401 atagccgaat ttttttgttg tatttacata ttgattggca atattgaaac caccggtata
     2461 actaatcttt ccatcgatca caacgatttt tcggtgatca tggtaattca atcggaaacg
     2521 aagtaatgcc ctttgtgagg taacaaatgt atggacatgt ccaccatttt tgattagacg
     2581 attgaaatct tttgcttttg tgccatgaga gccaaatgca tcatataata ttcgaacttc
     2641 cacgccttct gcggcttttt cttctaaaac atgtaagact tgctggccga tattatctgt
     2701 cacaaatgcg taatattcga tatggatcga atgtttggct ttttttagat cttgaagcag
     2761 tgaatccaat ttctcttgtc cgtctgtgag aagagtgaca gaattcattc ttgtcagcgg
     2821 catacgattt aatgaagaga agaagtcaac aaattgctgt ttgtctttat cgcccatgtc
     2881 aggatcgtaa tgttcaatgg tatctcctct aaaagactga aagttttcta attctttcaa
     2941 gtcactttgt cggagataga attttttctt atccgttaat ccacgtccga aaaataaata
     3001 taatacaaag cccaccccag gaagggcaaa caatactaag agccatgccc aaatggctgc
     3061 tacatctcgg ggtttgatca aaatagccac caaagcaata agtgcattta atagataaag
     3121 ggcggttata atactagata ccacaaaaat gttcctcctt acatacaata acattagtat
     3181 agcatgatag aagaaagaag cctaccaagg tgaatatact tttcactcct ttcatgaaaa
     3241 tgtaggtaaa tcgggctaaa gtagttgctt tttgtaggtt aataaggtag gatattagta
     3301 cagttgaata tctccttagg ggagtaaccg gcaacgtttg ttgcgataat atcaacagta
     3361 agttaaccaa atggttttct ggtattgtat gaaatggtga gacctaagac aaatgcgtat
     3421 ttgtcttagg tctctttttt ttcagacagg actagggcca agatcaaaaa atgggggatg
     3481 aaatttggaa aacaaggaac aagcacaaca agcggtctat aaagaaacga tcgactcgtt
     3541 gatgcagcaa acgcagagct caaccgatgg attgagcacc acgcaagcga aggaaaaatt
     3601 agaaagagat ggcttgaacc agctaaaaga aaagccgaag aagccaactt ggaaattgtt
     3661 cttagaaact ttcaaagatg caatggttat cgtattgctg attgtcgcac tgattcagat
     3721 ggtcatgggt gactacatcg aattcttagt tatttttgca gtattgatgt tgaattctat
     3781 aatcagtgtt gtccaaacaa aaaaagcaga aggttcttta gaagcgttga aaaacctttc
     3841 agcgcccgat gctcgagtga ttcgtgatgg taaggaaaaa acgattccgg caaacgaact
     3901 tgtggtagga gatatcgtgt tgttagacgc aggcgattat gtacctgctg atggacgttt
     3961 actagatgcg ggatcattaa aagtagatga aggtatgctg acaggagagt cgacttctgc
     4021 agaaaaagaa gtaacggata tcacaagtac ggtaccaatc ggagatcgta caaatatggt
     4081 attcagtgga acgatcgtaa cttacggacg cggtaaattc ttagtgactt caactgggaa
     4141 taatacggag atcggacaag ttgctggcct tttggaatca acaactgagc aagtcactcc
     4201 gttacaacga ggtctggata aattcagtaa aaaactaagt ttggctattt tggcattgtc
     4261 tttattgatt ttaggtatcc aactgtttcg tatttatctt ggagaaggta caggagatat
     4321 gactgcagat atcgtcagcg cagtgatgtt tgccgtagcc gtagccgtag ctgctattcc
     4381 agaagcatta cagtctatcg taacaatcgt gttatctttg ggaacgaata aaatggcaaa
     4441 acgtcatgcc attattcgga agcttccagc agttgaaaca cttggttcga caagtatcat
     4501 ctgtacagat aagactggta cattgacaca aaacaaaatg acagttgttg actacttttt
     4561 aggtaatggc gatactgggg atttcacaaa tgacccttca aaatggacag ctgacgaacg
     4621 tcgcttgatc gaaatcagtg ttttagcgaa tgatgcatcg atcagtgaag acggtactaa
     4681 attgggcgac cctacggaag tagcgtttat cgactttagt gaaaaattaa accagcctta
     4741 tcaggaaatc cgaaacaact acccaagaca agcagaactt ccttttgact cagatcgaaa
     4801 attaatgtct actggacaca caattgataa caaaaattac ttgtttgtta aaggcggacc
     4861 agatatcgtc ttccaacgca gtaaaaaagt attgctaaat ggtgaagtcg ttccgatgac
     4921 ggatgaattg atgaaaaaat tccaagagca aaatgaagct ttttcaacac gcgcattacg
     4981 tgtactagct tttgcttacc gtccacttga taattttgat ttatcatttg aagatgaaga
     5041 cgatttgatc cttgttggtt tgcttgctat gatcgatcct ccacgtgctg aagtgactca
     5101 ggcggtaaca gaagcaagaa gtgcaggaat caaaacaatc atgattactg gtgaccacaa
     5161 aacaacagct gttgctatcg caaaacaaat cgggattttt gaagaaggaa acctggcttt
     5221 gaccgggacg gaactagatg aattgacaga agatcaacta aacgaagttt tagaaaaagt
     5281 cactgtttat gcacgtgttt cacctgagaa taaaattcgt atcgttcgtg cttggcaaaa
     5341 taaaggtcat atctcagcta tgacaggtga tggtgtaaat gacgcaccag cattgaaaca
     5401 agcagacatc ggaattgcta tgggaacggg tacagatgtg gcaaaagatg cagcagcgat
     5461 ggtattgacg gatgataact ttgcttctat tgtcagcgca gtagaagtag gacgtaatgt
     5521 gtttgataat atcaagaaag ctatttctta tctatttgca ggaaatttag gtgcgatcat
     5581 tgcgatcatc tttgccttag ttgctgactg gtccaatcca tttacagcat tacaactgtt
     5641 gttcatcaat ttagtcaatg attcactgcc agcaattgca ttaggtacag aaaaagctga
     5701 acctgctacg atgaaccgcc cgccaagaga tccaaattca ggaatcttta cggacaaaac
     5761 attgatttct gtaacgtatc gtggtgtgct gattgggatt gctgttatct ttgctcaatg
     5821 gcttggcatg cagcattcac ctgaattcgg tgtagccatg tcattttcaa cattgatttg
     5881 gtgtcggaca ttgcaaacat tcccagcacg ttcaaacaca caaacagcta tccaagcagg
     5941 gttcttctct aacagaagtg tcttactagc tgtagttgta tgtagcgcgc tttactgctt
     6001 aacaatgatc ccaggactga aagaagtctt ctctatccca tcagcatttg gattgacaga
     6061 agtctttaca tgtatgggaa tcgcacttgt gacaattgtt ttgatggaaa tcactaaatt
     6121 gatcattgta cgagtacaag gaaataaata aaacgaatca acgaggttgt gagcctgccg
     6181 tttaattctg agtcacaagg tgcaatttca acaaacagct tctcatgttt gttgaatatt
     6241 gtgacttgtg accgaagagt tggcaggaga acaccgttta aggaagaagt tgtaaaatca
     6301 gcattttgag ctaatactga gggtcatctg attggacact gtttattcgg aaagagggac
     6361 tttgacacga ctttggtcac agtccctttt tttatttatg atagacggaa agccaatcat
     6421 tttattattc atcaaaagag atagaataga taaaagagga gaatgattta ttccgaaaag
     6481 tgaaaacata taacaaaaaa ttagaggaaa tcaaatgaat gaaaaagaat gggatgaatt
     6541 tgctgaagaa tattatgaaa tccagcaaga atcgcaagta actattgctg aagatgtaaa
     6601 aaattatctg aaaacggaga aagtcctgcc tgctgaaaca gcagcagacg ttgctggagg
     6661 atctggcaga tttctttcct tagcaaaaga aattaatcgc tatgatttga tcgatttttc
     6721 ttcaggaatg ctagaaaatg caaaaaaaga agcagaaaaa aatgagttgc caaatgtttc
     6781 ctttatcaaa cagtcgttag aagaatttat ccaatcaaat gagacatatg aaatggtttt
     6841 tacagcagca aatccagcat tggtacatct tattcaatta gaaaaattga tgaaaaagtc
     6901 aagcaaatgg tgcgtgataa tcagagtagt ggaatcaatc gatgatgttt tttatcctat
     6961 cgaaaagcaa ctaggaatga tagaagaaga tcctaataca tcgccagttg taatggatca
     7021 atttgaaaca tacttaattg atgaaggatt caaagtgaag aaaaaagatt ttacttattt
     7081 tacacaggaa tcaattactg aagaattgat gaagctatac tatgacgcgt acgcaaaaga
     7141 tcctgttgtg accaggtaca ttcgcaaact attcagtgaa aaacgagaaa tccttagtac
     7201 gactaagctg acctatagac tgctcctttg gtccgcagat aaaaaaagaa cctttcacga
     7261 ctcgtgaagg gttcttttta tgattttatt atattttgta gtaacgaata tcattttcga
     7321 tctttgtaat cgaaaaaggt acatctgaag tatattctgc acattctccg tgttcaggaa
     7381 gcgtctcact gaaaatcgtt tcatattcgt caacagtgat ccgtgttcga gaatctagca
     7441 tctcttgatg agattgtgcg aagagatatt cttgatagtt ttcttccaga taacctgtaa
     7501 aaaattcact tactgcacca gaaccgtagc tgaatagacc gatgcgatct cctggctgta
     7561 gtgatttcga attttccagt agagaagtta gccccaggta taatgaacca gtgtaaagat
     7621 taccgattcg tcggctgtaa cggatgcttt cttcatagcg agccataaga cgttcctgat
     7681 tttcttcgtc tgtttggtct aatacgcttt gcaatgcctt ttttcccatc ttagtatacg
     7741 gaatatggaa agcaatcgcc tgataatctt cgagtcctcg acccgacaat tctttatgtc
     7801 gattccaaac tttttggaat gattcgatat acgtagaatt agataaagga ccatcaacaa
     7861 caggaaattc gctataatct ggacgccaga aatcatagat atcttctgtc agaaatacgc
     7921 tgtcgtcttc aatcgataaa atacgcgggt tttgagtgat catcatcgca acagcaccga
     7981 caccttgcgt cacttcacca ccgcttgcca agctgtaacg agcaatatca cttgctatga
     8041 ctagtacttt tcgttctgga tgatttttga catattcttt cgccatgtgc aaagctgcgg
     8101 tgccaccgta gcaagcctct tttacttcaa aagaacgagc aaaagattgg attttcagta
     8161 aatggtggat aattaccgca ctcgcttttg aatgatcaat cccggattct gttccgacga
     8221 tgaccatgtc gattagctca cggtcttttt ctgttacgat tttgctggca gcatttgctc
     8281 ctagtgtaat gatgtcttca tttgcacgat tgactgccat ttggtcttga ccaatcccta
     8341 tatggtattt tgcaggatca tccccacggc tttctgccaa ctctgtcata tctaaatata
     8401 aattaggaat aaaaaaggaa agacgatcaa tccctatttt catttcaaca cctctttact
     8461 tatgataaaa aacttacttt actaaggtat cataaaaaga ttaaaagaaa tataaaaaag
     8521 agaatattta aggattgtta aaatttaatc ttagaaaaaa ataactggaa caagagctat
     8581 ttgtttttac agcaaagaat ggtatatttt tgtaggaggt ggcttacttg aaagaagtcg
     8641 ttatgataga tgctgcaaga acgccgatag gaaagtatcg cggaagttta agtccattta
     8701 ctgcagttga attaggcaca cttgtgacta aaggattatt agataaaaca aaactgaaaa
     8761 aagataaaat cgatcaagta atatttggaa atgtcctgca agctggtaat ggtcaaaatg
     8821 ttgccagaca gattgctttg aacagcggtc tccctgtaga tgtcccagca atgacgatca
     8881 atgaagtttg cggatctggt atgaaagcag tgatcttagc acgccagctg atccaattag
     8941 gtgaagcaga acttgtgata gccggcggaa cagagagtat gtctcaagca cctatgctga
     9001 aacagtatca gtcagaaaca aatgaatatg gtgaaccaat ttccagtatg gtcaacgacg
     9061 gattgactga cgcattttca aatgcacata tgggattaac cgcagagaat gttgcaacac
     9121 aattttctgt gagcagagaa gagcaggatc gctatgcctt gtcgtcccag ttgaaagcag
     9181 cacatgctgt cgaagccggt gtattttctg aggagatcat cccagtcaag atttctgatg
     9241 aagacgtgtt atctgaggat gaagcagttc gtggaaatag tacattggaa aaactgggca
     9301 cgttacgtac agtattctca gaagaaggaa ctgtaacagc aggaaatgct tccccgttga
     9361 atgacggtgc ctctgtggtg atccttgcat ccaaagaata cgcagaaaat aataatctgc
     9421 cttatttagc aaccatcaaa gaagtagcgg aggtcggtat tgacccaagt atcatgggaa
     9481 tcgctccaat caaagccatt caaaaattga cagatagatc aggaatgaat ttatcaacaa
     9541 tcgatctttt tgagatcaat gaagcatttg cagcttcttc tatcgtagtt agccaagaac
     9601 tgcagttaga tgaagaaaag gtcaatatat atggaggagc aatcgcatta ggccatccaa
     9661 ttggtgcaag cggtgcacgt atcttgacta cattagctta cggattgctt cgtgaacaga
     9721 agagatacgg tattgcttca ttatgtattg gtggaggttt aggcttggca gtcttgttag
     9781 aagcgaatat ggagcaaaca cataaggatg tgcaaaaaaa aaagttttat cagcttacgc
     9841 catctgaacg gcgcagtcaa ttaatagaaa aaaatgtatt gacacaagaa actgcgttga
     9901 tttttcagga acaaacactt tctgaagagc tctccgatca catgatcgaa aaccaagtga
     9961 gtgaagtgga aatcccaatg gggatcgcgc agaattttca aatcaatggc aagaaaaaat
    10021 ggattccgat ggcaacagag gaaccatctg tcattgcagc tgcaagtaat ggtgcaaaaa
    10081 tctgtggaaa tatctgcgca gaaacacctc agcggctgat gcgagggcaa atcgttctat
    10141 caggaaaatc ggagtatcaa gcagtgatca atgcagttaa tcatcgaaaa gaagagctga
    10201 ttctttgtgc aaatgaaagt tatccttcaa tcgtgaaacg cgggggcggt gttcaagata
    10261 tctctactcg ggaattcatg gggagtttcc atgcatactt atctattgat tttttagtgg
    10321 atgtaaaaga tgcaatgggc gctaacatga tcaactcgat tcttgagagt gtggcaaaca
    10381 agttacggga gtggttccct gaagaagaga ttctattcag tattttaagt aattttgcta
    10441 cagaatcatt ggcttctgcc tgttgtgaaa tcccattcga acgcttaggg agaaacaaag
    10501 aaatcggtga acaaattgcc aaaaaaatcc aacaggcagg ggaatatgcg aagcttgacc
    10561 cttaccgtgc agcaacgcac aacaaaggga tcatgaatgg tatagaagct gtagtggcag
    10621 ctacaggaaa tgatacacgt gcggttagcg cttcgatcca cgcctacgcg gcaagaaatg
    10681 gattatacca aggattaaca gactggcaga tcaaagggga taaactagtt ggaaaactaa
    10741 cggtgccttt ggctgttgcc acagtaggcg gagcttccaa tatcctgcca aaagcaaaag
    10801 catctttagc tatgttagat attgattcag ccaaggaact agcacaagta attgctgcag
    10861 tagggttagc tcaaaacctg gctgctttgc gtgcattagt tacagaagga atccaaaaag
    10921 gccacatggg acttcaagct cgttcattag cgatctcaat tggggctatt ggtgaggaaa
    10981 tcgagcaagt tgcgaaaaaa ttacgtgaag cagaaaagat gaaccagcag acagctatac
    11041 aaatattgga aaaaatccgg gaaaaataaa aaagcaatat ctttagaaga ataaagcaag
    11101 atttacagtt attttattta ctgcagatct tgcttttttg gctcttcgtc aaattgtgtt
    11161 ggcgaagaca aatttgaata aaacttagtc cgatatgcgg cgcgttctgt gcgccgcata
    11221 tttttttagt tttcaaagat cagaccttgt tgtaaataga tccgtgcccg aaagttataa
    11281 aagttgcgat aaccaaacgc aattcgttta atcagcttga tcttgttatt cagcccctca
    11341 gtgacgccgt ttgagtgggg caccttaaag gcatttgaaa tacccgattg gtagcgatgg
    11401 aagatcgtga atttcttttt aaacgactga ggtaacgtag atgaaattgt tttaagggtt
    11461 tcttgaaagc cttccgta
//
LOCUS       DAMEEU010000086        11357 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.087, whole genome shotgun sequence.
ACCESSION   DAMEEU010000086 DAMEEU010000000
VERSION     DAMEEU010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11357)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11357)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11357
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.087"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            311..1090
                     /locus_tag="PB779_002403"
     CDS             311..1090
                     /locus_tag="PB779_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739908.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSSVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADIQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTVLSQIEQIRNEKISAAYATKAQTVAEQMGYSNISY"
     gene            1136..2080
                     /locus_tag="PB779_002404"
     CDS             1136..2080
                     /locus_tag="PB779_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDE0739909.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVATVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFPIGKITLNGDQALSYSRMRYEDPNGDYGRQGR
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMNFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            2096..2875
                     /locus_tag="PB779_002405"
     CDS             2096..2875
                     /locus_tag="PB779_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HDE0739910.1"
                     /translation="MEETISLKEIFETLRKHLVIIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     EQIKDAISVNQAENSQMFSIQAISTNAVAAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLMTGLMLGMMVGVGLAFLLELLDRTVKDEKYVTDTLGFPILG
                     TVPEMSAKELNAGIRKKGPAQTQPKATNDKTAPSRRSRSRV"
     gene            2887..3585
                     /locus_tag="PB779_002406"
     CDS             2887..3585
                     /locus_tag="PB779_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HDE0739911.1"
                     /translation="MARTQKQKAAQTHAVSLVTLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVIYKTFKLNNAS
                     GLSTVLSSSGSVADEIQRTPVDNLSILPSGPKPPNPSELLSSPRMDQILAEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLTKAKELLDMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            3613..4377
                     /locus_tag="PB779_002407"
     CDS             3613..4377
                     /locus_tag="PB779_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HDE0739912.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAERLFFELLELGKIPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQLTAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKEFG
                     KEKVVQMKQVAKDLINGDEINYPIYEEVKKKKFGLF"
     gene            4421..5872
                     /locus_tag="PB779_002408"
     CDS             4421..5872
                     /locus_tag="PB779_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HDE0739913.1"
                     /translation="MYRKNSSGWSKHIDFILLDLFCVQLAFYISYVMRQGDWNPYVIP
                     IYRHMAIFIELENLTIIFLFEAYKNVLKRGYYKEAVASIKQSFMLLLVCSLYLITMQD
                     GNDYSRVSLFIMGVVYGLLTYIIRILWKGLLHHRMKNGEDVSLVIVTSQKIAKNVVRN
                     LKEKNYGMYKLSGVIVVDRDMYGTTIGGVPVVANADNAAEYLLQNWVDEVFINVDESV
                     PYPKELIARCSEMGLAVHMNLTKVSDSTRGKQFIGRVGDYTVITSSINVMTMRQAFIK
                     RTIDILAGIIGCIATGVIFIFVAPVIYIKSPGPIFFAQERIGQNGKTFKMYKFRSMYM
                     DAEERKAELMKENKMSNNLMFKMDFDPRIIGNKILPDGTKKTGIGQFIRSTSLDEFPQ
                     FYNVLMGKMSLVGFRPCLKSEYEKYDFHHRARIAMKPGITGMWQVSGRSDITDFEEVV
                     KLDAEYIRNWSMGLDFRILFRTVKTVLHRNGSM"
     gene            5904..7040
                     /locus_tag="PB779_002409"
     CDS             5904..7040
                     /locus_tag="PB779_002409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HDE0739914.1"
                     /translation="MARKKLKICMLGHKRIPSREGGIEIVVEELATRMVALGHEVTCY
                     NRSGHHVSGKEFDQHKNKEYKGVKLKTIFTLNIKGIAAMSSSVFGGIRAAFGKYDIVH
                     FHAEGPCAMLWLPKLFGKRCVATIHGLDHQREKWNKLASTYIMLGEKCAVKFADEIIV
                     LSESVQNYFEDIYGRKTRFIPNGVKKIEIKSAGLITEKYGLTKDSYILFLGRLVPEKG
                     IRYLIEAFKDVQTDKKLIIAGGSSDTDEFANELKELAKGDERIIFTGFVQGQELEELY
                     SNAYIYTLPSDLEGMPLSLLEAMSYGNCCIVSNISECTEVVEDKAMIFKKSDVSDLKI
                     RLEEACNQSEMVKVLKNQATEFICSKYNWDKIVQETLNLYRGNI"
     gene            7040..8146
                     /locus_tag="PB779_002410"
     CDS             7040..8146
                     /locus_tag="PB779_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HDE0739915.1"
                     /translation="MIRILQCVNDMHRAGLETMLMNYYRNIDRTKIQFDFLTHRPYKS
                     DYDEEIISLGGKVYYAPRLYPQNYPKYFKWMEQFFKDHPEYEIVHSHIDAMSYLPLKA
                     AKKAGIPIRIAHSHNTSIDRDFKYLLKQYYRCKLTSVLTHEFSCGKVAGDFLFRNDKF
                     TLIPNAVDAKKFYYDESIRNDVRMKLGISSQTFVMGHIGRISYSKNHRFLIEIFKEFH
                     AIKNNSVLLIIGTGDMEEEIKNYAKKSGIDDDIKFLGNRNDIEKFYQAFDVLMLPSLF
                     EGVPLVGIEAQFADLPCFFSEKVPTEVAFSDKTNFISLNQSAKEWAREIANVDISHRD
                     SERSILIKADYNIQTAYKILESKYYELFELIQRG"
     gene            8152..9174
                     /locus_tag="PB779_002411"
     CDS             8152..9174
                     /locus_tag="PB779_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide synthesis protein"
                     /protein_id="HDE0739916.1"
                     /translation="MTQKHSSIKRIIHRISEELNATRRIAKITSWKEAFATLQAKIDI
                     QVMNRNGYNESKKQKEHLLKKHEVMLKYYEKTFSDFLKTYDYSQNQIINQSKSPYSNC
                     IWVCWWQGLDQSPEIVKACVKSIKRNAGKHTVIILTEDNYRQYVDIPKWVEEKKNKGI
                     ITRTNYSDLLRLSLLAKHGGLWLDATFYCTKPIPDEYFDIDIWSIRRPDYAHASVASG
                     YFAGYSLACNQESRWMFAIIRDFFLNYWKNNDMMVDYLMIDYMIVLAQRINHEIAQTF
                     DKIPSNNPLCDELIKNLNNIYDEKVWNLLKKDTLLFKLTWKQSFKKQKDDKVTFYGML
                     VENKLL"
     gene            9196..10251
                     /locus_tag="PB779_002412"
     CDS             9196..10251
                     /locus_tag="PB779_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HDE0739917.1"
                     /translation="MKHKVSVIVPIYNVEKYLRKCVDSLLSQTLKEIEIVLVDDGSPD
                     ASGEIADEYQKKYSNVKTIHRENGGLGPARNTGIENATGEYVAFLDSDDWVESDMYEK
                     LYLVASKENADIVVSGHCDFANDKAMVKKQHPLSGNVYDTPNSIKNVRKNLFGHSPKD
                     QEVEAFPMSVCMSLYNKNLLDKYRLRFEKILSEDTIFNLNAYDVANKIAFTEYTDYCY
                     RKEEQESITKSLSPNKQTEFKEFLITLKAIASKEDLECQIRAKRMAIDYCRLYVGLVD
                     DANLGIKEKRKYIKKFIEDEGLIQCWKGYPTNTLPFQQKFFHKMLECKCYTILLLLSR
                     IRKIIKNMTRKKLFIIL"
     gene            10869..>11357
                     /locus_tag="PB779_002413"
     CDS             10869..>11357
                     /locus_tag="PB779_002413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739918.1"
                     /translation="MSVKKMLFMVSTIIVLTSRFWGINTSLSMRYFIMAIWDLYFMLS
                     YFSYREKTYKKYVIKNNFWLTIMPFVIFSIYTLIIWGIGSNAEFENFIKLCSTLLYLI
                     LAYGYACTAFYLFKAEGIDFIFWSGVISYMSGSVFYLIVSYGLNGLISYIKSLITGET
                     NTA"
BASE COUNT         4154 a         1547 c         2278 g         3378 t
ORIGIN      
        1 tattattaat tcaatgttaa tttttttgtt attctatttt ttgtgtaact tttaaaaaca
       61 cctatgaaaa ttatggaaat aaaaatgaaa tcgattaatt tttatcttat taatgtttta
      121 tttactttta aatcgtaaat tgccctagtc aagaaaacag tttgtggtat gattatatag
      181 ggaaaacttg tttacaaata tttctgtgaa tatattagtt taattatgtt tttttaaata
      241 aaaagctgtc atttttatgt aagtgaatta tatcttaatt tatctatcat caatacttag
      301 gagtgaatct atggaaaagc cattcgtcaa gtcattgact gctgtggcgg taggtgcagg
      361 tgctattgcg atctgtttgt ttggatacca tatcaataat cagcggcaac atcagcaacg
      421 gatcaattat gcagaatctg ccatcaccaa tcaaaaagac accttgactt ctttatcaaa
      481 agaagtagac aagctgtata gtacaaaaga aaaaattttt ctaaaccctg aaataacaga
      541 agaaacaatc acaagtttgt caaataagct atcctctgtc aaactttcag cagatgatta
      601 cgacatcaaa gaatcagaat tgcctaaaga agctgttgca atccaagatg agaagaaagc
      661 aatcgtgaca cagttagata gtgcagaatc aaaactgaag atccagacag ctgtcaacga
      721 tttatttact aaaaatgtat caaactggca gcaagctgta gacgatgtca tcatcaaaga
      781 aaaggtgaca agtgcagatg tcgctcgtgt acgtgaaaat atgagctttt ttaaagatag
      841 tccttggaaa acggttgtta tgcaatatct aggattcgct gatattcaga tcgcgcaagt
      901 cacgcaacta gatcagttat tcgatacgat gttaaaggat ggtcaagtga ctgccaccgc
      961 tacttacgat caatatttga cggtgctcag tcaaatagag cagatccgga atgaaaaaat
     1021 aagcgcagca tacgcaacaa aagcacaaac tgttgctgag caaatgggct atagcaatat
     1081 aagctattga cagttaaaac gttgattcaa gcaaggttag caaacggagg aaactatggc
     1141 aagacgaaga agaaaatcaa gagggaaaaa aatatttctg attattttag cagttcttat
     1201 cgtattagta ttagcaattg taggagtagg agcaaaatta tatctggatc tctcacattc
     1261 tattgagaaa acttacgaat cagtggaacg aacccaagga gaacgaacga aaccagttga
     1321 tctggacaaa caagaatctt tctctgttct attgatgggg attgatactg gagatttagg
     1381 tcgggtcgat caaggaagat cagatacgat gatggttgcc acagtcagtc ctgaagacaa
     1441 acagacaacg atcgtcagca ttcctcgtga tacgtatgtc gacatcgtag gtcgtgacac
     1501 aaaagacaag atcaaccacg cttacgcatt cggcggagct gccatggcga tggataccgt
     1561 acaaaaatat gtagacatcc caatcgatca ctatgtctct atcaatatga aagggctaaa
     1621 ggaactcgtt gatgcagttg gtggtatcga agtcaataat gacctcactt tctcacaaga
     1681 tggctatgac tttccaatcg gtaaaattac attgaacggg gatcaggcat tatcttattc
     1741 tcgtatgcgt tatgaagacc caaatggtga ttacggtaga caagggcgcc aaagaaagat
     1801 cgtagaaggc gtagcgaaaa aagtattgag tctaaacggt gtcagcaact atcaatccgt
     1861 tttgaatgct ctagagtcga atatgaaaac agacatgaac tttgatgaaa tgaaaaaaat
     1921 tgctttagat tatcgggagg catttggtac gattaagcaa gatcagctgc aaggagaagg
     1981 cttcatgcaa gataatatct cctatcaaaa agtcagtgat caagaacttg atcgtgtgaa
     2041 aaaagaatta aaagatcaaa tgaatctaga gaataaatag gaaagtggag aaaaaatgga
     2101 agagacaatc agcttgaaag aaatttttga aacattacgc aaacacttgg taataatcat
     2161 catctcaatg tttgctggct tggccatctc aggaatcgta acatttttca tcttgacacc
     2221 aaaatacagt tcacaagcac aattgatcgt gacactgcca caatcagaca ctgcaaatgt
     2281 caatgatgtc aatacgaacc tgcaaatgat caatacgtat aaagatatga tcgtcagtga
     2341 tttagtgctc aatgaagtca aagatcgttt agaaacagaa gacaatgtga aaatgactgc
     2401 tgaacaaatc aaagatgcca tctcagttaa tcaggcagaa aattcacaaa tgttctcgat
     2461 tcaggcaata agtacgaatg cagtggctgc tcaacagatc gctaacacaa cttcacaagt
     2521 tttccaagag aacgcaaaag atgtgatgaa tgttgataaa atctcgatca tttcaggtgc
     2581 agttgccaat acgacacctg tttcgccaaa taataaattg aatttaatga ctggcttaat
     2641 gttaggaatg atggtaggtg taggtctggc attcttattg gaattactcg atcggacagt
     2701 gaaagatgaa aaatatgtga cagatacatt aggattccca atcttaggaa cagttccaga
     2761 aatgtcagcg aaagaattga atgctggtat ccgtaaaaaa ggaccagctc agacacaacc
     2821 aaaagctaca aacgataaaa cagcgccatc acgcagaagc cgctcaagag tctaggagga
     2881 aagaaaatgg cacgaacaca gaaacaaaaa gcagcccaaa ctcatgcagt cagtttggtc
     2941 acactcacca atccctcttc accaatcgct gaacaatatc gtacgattcg gacgaatatc
     3001 cagtttgcct ccgcagctgg tcagcaaatc aaaacgattg ttgtgacttc atcaggacct
     3061 ggagaaggga aatcgaccac tgcagcaaac attgccgttg tttttgccaa atctggtcaa
     3121 cgggtgctgc tagtcgatgc agacttacgt aagcccgtca tctataaaac gttcaagttg
     3181 aacaacgcaa gcggattaag tactgttctt agttcatcag gaagtgtagc agatgagatc
     3241 caacgaacac cagtcgacaa tttgtcgatt ctgccaagtg gacctaaacc accaaatcca
     3301 tcagaactac taagttcgcc aagaatggat cagattttag cagaagcaag acaactattt
     3361 gatgtagtga tcttcgacat gccgccagtc gttgccgtaa cagatgcaca gatcatgtct
     3421 tcaaaaacgg atggcacctt attggtcgta cgggaaaata cgtcacgaaa agaatcattg
     3481 actaaagcaa aagaactgtt agatatggta caagcacgag tcttaggtgt cgtatacaac
     3541 ggagcagaac acagcaaaga tgctggttat tactacggaa attaaggaat aagaagagag
     3601 gagacaagag aaatgatcga tctacattgc catatcctac caggaatcga tgacggggca
     3661 gaaaacttag aagcaagtat tgcaatggct gaaaaagcga ttcagcaagg cattacgcat
     3721 attttatgca caccacacca caataatgga aaatacagca atgaaaaatc acaagtcatt
     3781 tctctagtcg cttcgttaca agccgaatta gagaaaagac agttgccttt gacgttattg
     3841 gaaggacaag aagtacgtat taccggaacg ctcatcgaag acatccaccg agatgaaatt
     3901 ttatttacag atttagatga tacatatctt ctgatcgaat ttccgacact ggaagtgccg
     3961 ttatatgcag aacggctttt ttttgagttg ttagaactag gaaagatacc agtgatcgtc
     4021 catccagaac gcaacgcgca ttttcgagaa gacccaaatc atttgcttcc gttcctagat
     4081 atgggatgtt tggcccaact tactgcgcca agttatgttg gtgtatttgg caaagatatc
     4141 cagaaaacag ccaaaacaat ggtcaaacat aatctcgtgc agatggctgc ttctgatgca
     4201 cacggggtct ctaagcgcac cttttactta aaagagtgct atgagcagat tgccaaggag
     4261 tttggtaagg aaaaagtagt acagatgaaa caagtcgcaa aggatctgat caacggggat
     4321 gagatcaatt atccaatcta tgaagaggta aaaaagaaga agtttggttt attttagttc
     4381 tttattcgta gataaaaagg aaatgaggag agagtgagag atgtatagaa aaaactcaag
     4441 tggttggtct aaacatattg attttatttt attagactta ttttgtgtcc agcttgcttt
     4501 ttatatatca tatgtaatgc gacagggtga ctggaatccg tatgtgattc ctatttatcg
     4561 ccacatggca atttttatag aacttgagaa tcttacgatt atatttttat ttgaggcata
     4621 taaaaatgtt ttaaaaagag gatattataa agaggctgta gcttctataa agcaatcttt
     4681 tatgctgtta cttgtgtgca gtttatacct tattacaatg caggatggaa atgattattc
     4741 cagagtttct ttatttataa tgggggtggt gtatggatta ttaacatata taattcgtat
     4801 actttggaaa gggttgttgc atcaccgcat gaaaaacggt gaagatgtat cgttagttat
     4861 tgtaacatct caaaagattg caaaaaatgt agttcgtaat cttaaagaga agaattatgg
     4921 catgtataaa cttagtggtg tgattgtagt agacagagat atgtatggaa ctaccatcgg
     4981 aggtgtccca gtagttgcaa atgctgataa tgcagcggaa tatcttttac agaattgggt
     5041 agatgaagta ttcatcaatg ttgacgaaag tgttccatat cccaaagaat taatcgccag
     5101 atgttcggaa atgggacttg ctgtacatat gaatcttaca aaagtgtctg atagtacacg
     5161 tggaaaacaa tttattggcc gagttggtga ttatactgtt attacatcta gtattaatgt
     5221 tatgacgatg aggcaagcat ttataaagag aacgattgac attcttgctg gaattattgg
     5281 atgtattgca acaggtgtta tttttatctt cgtagcacca gttatttaca tcaaatcacc
     5341 agggccgatt ttctttgcac aagaacgtat tggtcaaaat ggtaagacat ttaagatgta
     5401 taagttccgt agtatgtata tggatgcaga agaacgcaaa gcagagttga tgaaagaaaa
     5461 taagatgagt aataatctca tgtttaagat ggattttgac ccaagaatca ttggcaataa
     5521 aatacttcct gatggaacaa agaagacagg aattggacaa tttattcgat ctacatcatt
     5581 ggatgagttt ccacaatttt ataatgtcct aatgggaaaa atgagcctgg tggggtttag
     5641 accttgcttg aagtcagaat atgagaagta tgattttcat catcgtgcga gaattgcgat
     5701 gaaacctggg attactggaa tgtggcaggt gagtggtaga agtgatatca cagacttcga
     5761 agaggttgta aaacttgatg cagaatatat caggaattgg agtatgggat tagattttag
     5821 aattttgttt aggacagtca aaactgtgct tcatagaaac ggttccatgt aagataaaga
     5881 tactatagaa ggagtaaaac gtgatggcaa gaaaaaaatt aaaaatctgt atgctaggtc
     5941 ataaaagaat tccatcaaga gaaggtggaa ttgagatagt ggtagaagaa ttggcaacgc
     6001 gaatggttgc acttgggcat gaagtgactt gctataatcg aagtggtcat catgttagcg
     6061 gaaaggaatt tgaccagcat aaaaataaag aatataaagg tgtaaaatta aagactattt
     6121 ttacattaaa tataaaagga attgcagcaa tgagttcttc agtatttggt ggaattagag
     6181 cagcattcgg aaaatatgat attgttcatt ttcatgcaga aggaccatgt gctatgttgt
     6241 ggttgccaaa actttttggg aaaagatgtg ttgcaacaat tcatggtcta gatcatcaaa
     6301 gagaaaaatg gaacaagctt gctagtacat acatcatgtt aggggaaaag tgtgctgtaa
     6361 aatttgcaga tgaaataatt gtacttagtg aaagcgtcca aaattatttt gaagatatat
     6421 atggaagaaa aacaaggttt ataccaaatg gcgttaaaaa aattgaaata aaatcagcag
     6481 gattgattac agaaaagtat ggattaacaa aagattctta tattttgttt ttggggcgat
     6541 tggttcccga aaaaggaatt cggtatctaa ttgaggcatt taaagatgtt cagacagata
     6601 aaaaacttat aatagccgga ggaagctctg atacagatga atttgcaaat gaactaaagg
     6661 aattagcaaa aggtgatgag cgaattatat ttactggatt tgtacaagga caggaattag
     6721 aagaattata tagtaatgcg tatatctata cacttccaag tgatttagaa ggaatgccat
     6781 taagtttgtt agaagcaatg agttatggga actgttgtat agtttcaaat atctcagagt
     6841 gtacggaagt agtagaagac aaggctatga tttttaagaa atcggatgta agtgatttaa
     6901 agataagatt agaagaggca tgcaatcaat cggaaatggt taaagttttg aagaatcaag
     6961 ctactgagtt tatttgtagt aaatataatt gggataaaat cgtacaagaa acattaaatt
     7021 tgtatagggg aaatatataa tgattcgaat attacagtgt gtgaatgata tgcatcgtgc
     7081 agggttggag acgatgctaa tgaactatta taggaatata gatcgaacta aaattcagtt
     7141 tgattttttg acacatcgtc catataaaag tgattatgat gaggaaataa taagtcttgg
     7201 aggaaaggtc tattatgcac cgagacttta tccacaaaat tatcctaaat attttaaatg
     7261 gatggaacaa ttttttaagg atcatccaga atatgagatt gttcattctc atattgatgc
     7321 gatgagttat ttacctttaa aagctgcaaa aaaagctggg attccgatac ggatagcaca
     7381 tagccataat acatcgatag atagagattt taaatatctt ttaaagcaat attatcgatg
     7441 taagttaacg tctgttttga cacatgaatt ttcatgtgga aaagtagcag gtgatttttt
     7501 gtttcgaaat gataaattca ctttgattcc aaatgcagtg gatgctaaaa aattttatta
     7561 tgatgaaagt attagaaatg atgtacgaat gaaattagga atttcaagtc agacgtttgt
     7621 aatgggacat attggaagaa tttcatattc taaaaatcat cgttttttga ttgaaatttt
     7681 taaagaattt cacgctatta agaataattc cgtattatta attattggaa ctggtgatat
     7741 ggaagaagaa ataaaaaatt atgcaaagaa aagtggcata gatgatgata ttaaattttt
     7801 aggaaataga aatgatatag aaaaatttta tcaagcattt gacgtattaa tgttgccatc
     7861 attatttgaa ggggttccgt tagtgggtat tgaagctcaa tttgcagatt taccgtgttt
     7921 cttttcggag aaagttccta cagaagttgc tttcagtgat aagaccaatt tcataagttt
     7981 aaatcaatcg gcaaaagaat gggcgagaga gattgcaaat gtagatatct ctcatcgaga
     8041 ttcagaacgt tcgattttaa taaaggcaga ttataatatt caaacagcat acaaaatctt
     8101 agaatcaaaa tattatgagt tatttgaatt aatacaaaga ggttaaagaa tatgacacag
     8161 aaacattcaa gtataaaaag aattatacat cgcatatccg aagaattgaa tgcaacaaga
     8221 cgaattgcaa agataacatc ttggaaggaa gcatttgcca cgttacaagc taaaattgat
     8281 attcaagtca tgaatcgtaa tggatataat gaaagtaaaa aacagaagga acatttatta
     8341 aaaaaacatg aggtaatgct gaagtattat gaaaagactt tttcagattt tttgaaaaca
     8401 tatgattata gtcaaaatca aataattaat caatcaaaat caccatattc taactgcatt
     8461 tgggtttgtt ggtggcaggg attggatcaa tcgccggaaa ttgtaaaagc ttgtgtaaaa
     8521 tcaataaaac gaaatgcagg gaaacatact gttataattt taacagaaga taattataga
     8581 caatatgttg atataccaaa atgggtggaa gaaaagaaaa acaaaggaat cattacgaga
     8641 acaaattatt ctgatttatt aagattatct ttgctagcaa aacatggagg tttgtggtta
     8701 gacgccacat tttattgtac aaaaccaata ccagatgagt attttgatat cgatatttgg
     8761 tctattagga ggcctgatta tgctcacgca tccgtagcat caggatattt tgcgggttat
     8821 tcattagcat gtaatcaaga gtctagatgg atgtttgcta taattagaga ctttttttta
     8881 aattattgga aaaataatga tatgatggtg gattatttga tgatagatta tatgattgtt
     8941 ttagcacaga gaataaatca tgaaatagca cagacatttg ataaaatacc tagtaacaat
     9001 ccattatgtg acgaattgat taaaaattta aataatatat atgatgaaaa agtatggaac
     9061 ttattaaaga aagatacttt actgtttaag ttgacatgga aacaatcttt taaaaagcaa
     9121 aaagatgata aagttacttt ttatgggatg ttggtagaaa acaaattatt ataaatatta
     9181 gaggtataaa aagttatgaa acacaaggta agtgtgatag taccaattta caatgttgaa
     9241 aaatatttaa gaaaatgtgt ggatagttta ttgagtcaga cattaaaaga gatagaaatc
     9301 gtattagttg atgatggttc gccagatgct tcgggggaaa tagcagatga gtatcaaaaa
     9361 aaatattcta atgtaaaaac aatacataga gaaaatgggg ggttaggacc ggcaagaaat
     9421 acaggaattg agaatgcgac aggagaatat gtggcttttc ttgattcaga tgattgggta
     9481 gaaagtgata tgtatgaaaa attatactta gttgcgtcca aagaaaatgc tgatatagta
     9541 gttagtggac attgtgattt tgcgaatgac aaagctatgg tgaaaaagca acatcctttg
     9601 agtgggaatg tatatgatac gcctaatagt attaaaaatg tacgaaaaaa tttatttgga
     9661 catagtccaa aagatcaaga agtagaggcc ttcccgatgt cagtatgtat gtctttgtat
     9721 aataaaaatc tgctagataa atatagacta agatttgaaa aaattttatc tgaagataca
     9781 atttttaact tgaatgcata tgatgtcgca aataaaattg cttttacaga atatacagat
     9841 tattgttata gaaaagaaga acaagagtct attacaaaaa gtttatctcc aaataagcag
     9901 acggaattta aagaattttt aataactcta aaagctatag catcgaaaga agatttagaa
     9961 tgtcaaatca gagcaaaacg tatggcaatt gattattgta ggctttatgt gggcttagtt
    10021 gatgatgcaa atttgggaat taaagagaaa agaaagtata taaaaaaatt tattgaagat
    10081 gagggattaa ttcaatgttg gaagggatat cctacaaata cgctaccatt tcaacaaaaa
    10141 ttttttcata aaatgcttga atgtaagtgt tatacaatat tgttgttgtt aagtagaatt
    10201 agaaagataa ttaaaaatat gaccagaaaa aaattgttta taatattata aactaaaagt
    10261 atatcaaata atagaaatta acaagttaca aaaaaatatt ataaagaata atattttcta
    10321 aaaagtaaac tatagtaatg tggattatca ccttccaaca gtatataaaa tgagcgtaaa
    10381 aacggctatt tttgccttaa caacgatttt tttgtataca aatacgatat gctcattaat
    10441 tattggaatt tgtagtgctg tttaaattaa tgaaggtgta attatatgag tgatcatttt
    10501 gaaaaagttt gttgagaaga tgtgcttcta gtcatgtgat gggagaaaat aatttaactg
    10561 ttagagtgaa tagttaaatt attctggtta tatgaaaaaa gtagtttcta aaataatctt
    10621 gcagggatta acttaaagaa attgagagaa tagtttcttt gaaatttcta tatacaatga
    10681 gaagctgaaa tttactttta tttgatgact ggaaatagaa attaaatata ttgtattgtt
    10741 acattaaaga aaacttgtat ggaaaaatca gtacaatacc attatttaat gttcttcact
    10801 taaagcgcaa aaaatatcag tttattaaac tcgtatatag aacaaatata tgtagacggg
    10861 gcgaaacgat gagtgtaaaa aaaatgctat ttatggtaag tacaataatt gtattaacat
    10921 cccgattttg gggaattaat actagtttat ctatgcgata ttttattatg gcaatatggg
    10981 atttatattt tatgttaagc tatttttctt atcgtgagaa aacatataaa aaatacgtta
    11041 tcaagaataa cttttggttg actataatgc cgtttgtgat attttctatc tatactctaa
    11101 taatatgggg aattggttca aatgcagaat ttgaaaattt tataaagtta tgttccacgt
    11161 tgctttattt aattcttgca tatggttacg catgtacagc attttactta tttaaggcag
    11221 aaggaattga ttttattttt tggtcaggtg ttatttcata tatgagtggt tcagtttttt
    11281 atttaattgt atcttatggt ttaaatggtt taatttctta tataaaaagt cttataacag
    11341 gtgaaacaaa tactgca
//
LOCUS       DAMEEU010000087        11178 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.088, whole genome shotgun sequence.
ACCESSION   DAMEEU010000087 DAMEEU010000000
VERSION     DAMEEU010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 11178)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11178)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11178
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.088"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            136..309
                     /locus_tag="PB779_002414"
     CDS             136..309
                     /locus_tag="PB779_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739919.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            949..1422
                     /locus_tag="PB779_002415"
     CDS             949..1422
                     /locus_tag="PB779_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HDE0739920.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            1431..1658
                     /locus_tag="PB779_002416"
     CDS             1431..1658
                     /locus_tag="PB779_002416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0739921.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
     gene            2294..2665
                     /locus_tag="PB779_002417"
     CDS             2294..2665
                     /locus_tag="PB779_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739922.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
     gene            complement(2921..3163)
                     /locus_tag="PB779_002418"
     CDS             complement(2921..3163)
                     /locus_tag="PB779_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDE0739923.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(3195..4097)
                     /locus_tag="PB779_002419"
     CDS             complement(3195..4097)
                     /locus_tag="PB779_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDE0739924.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            complement(4110..4298)
                     /locus_tag="PB779_002420"
     CDS             complement(4110..4298)
                     /locus_tag="PB779_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDE0739925.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="PB779_002421"
     CDS             complement(4312..4875)
                     /gene="amaP"
                     /locus_tag="PB779_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDE0739926.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            complement(4913..5806)
                     /locus_tag="PB779_002422"
     CDS             complement(4913..5806)
                     /locus_tag="PB779_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0739927.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKDAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            complement(5884..6807)
                     /locus_tag="PB779_002423"
     CDS             complement(5884..6807)
                     /locus_tag="PB779_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HDE0739928.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            complement(6856..7206)
                     /locus_tag="PB779_002424"
     CDS             complement(6856..7206)
                     /locus_tag="PB779_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HDE0739929.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            complement(7239..8141)
                     /locus_tag="PB779_002425"
     CDS             complement(7239..8141)
                     /locus_tag="PB779_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDE0739930.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            complement(8134..8991)
                     /locus_tag="PB779_002426"
     CDS             complement(8134..8991)
                     /locus_tag="PB779_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HDE0739931.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            9325..10134
                     /locus_tag="PB779_002427"
     CDS             9325..10134
                     /locus_tag="PB779_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0739932.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIAMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            10174..10671
                     /locus_tag="PB779_002428"
     CDS             10174..10671
                     /locus_tag="PB779_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HDE0739933.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(11056..11129)
                     /locus_tag="PB779_002429"
     tRNA            complement(11056..11129)
                     /locus_tag="PB779_002429"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(11093..11095),aa:Ile,seq:cat)
BASE COUNT         3273 a         2091 c         1876 g         3938 t
ORIGIN      
        1 ttttcggaga attaaaaaat acaataaata actttagtta ctttaatgcg ttcttacttt
       61 atttttatat tatcattttt cttattcact tctttggttt atactattct tataaataaa
      121 aacgaggtat gtcctatgat gaaaagattg tactattcat tgatcataac gattggctat
      181 ttgattgtat caaatctagg aaatatggta tttggtatca gtaaagaatt cagttggact
      241 actacattat gggaatctct attctttttc atcttcgtat ttttgttaca aaattatcga
      301 aaaaaataaa catgtgccat ctatctgttg gcacatgttt taggatttat ggtacttttt
      361 attcggcaat ccattttatt tttctacttc ttcttaatac ctctaacact tttgatttat
      421 aaactaatcc aatgcatcta cttgcgctta ttaagctatt tcagctagat agtaccaccc
      481 catgcgtcaa tgcttgattt tccttttgta taacattgta taagcaataa aggacaaata
      541 agtggtgatt acaccaaacc attgaataag aaaaattctg atacgtaaat aaacatgaac
      601 ttgaaaaaat taatgaatcg gttagctact acgtagttgt cttttttctc atacagttct
      661 gttaacttac acttctcttc gctagataat aaaaaatcct ccaactgtat tgtccaatat
      721 aatcccaggc atctaaacta gcattataga agagacacac atagaatcta aaataactgg
      781 ttttaaatgt ttcttacaat caaaaaaagc tgttaaatgc actccacacc ttcatactct
      841 atcatttttt ataaacgata tatttttatt gtttttcgat aaaaaatagt tgttttacaa
      901 taattattct gctatatttt agctatcaaa gataaaagag ggataaaaat gaaatttaaa
      961 acattgctat taaaatttgt cgttttaggt ataagtgccg tatttatttt gttcggcgta
     1021 cttttttata ctcagatcgc tacaagcgaa aaaggattca attttgattg gcagaccaca
     1081 ttatttgttt ctgtcattta ctttgccctt ctcctaggga tcgttattgc ttatttctta
     1141 ttgaaactat tgaaaaaaat cgaagataac caagcttttt ccactcaaag cttaaacata
     1201 ctaaaaaaaa tcgaacgaac cattttgttt attggtttcg ccttttttgg cttacttcct
     1261 aaatttatga aagtagcgga tttagacgat gctccaggtt tgatgttggt aggaatcgct
     1321 gtcgtattca ttccttttgc agtatacaca ttaacaagcg tgctggaaaa actgcttgaa
     1381 catgcgattt tacttaagac agatcatgat ttgacagtgt gaggtgcgac atggcaatta
     1441 tcgttaattt agatgtagta ttagctcaaa aaaaaatgag tgtgactgaa ttgagtgaga
     1501 aagtgggcat tacgatggca aacatctcta ttctaaaaaa tggaaaagca aaagccatcc
     1561 gtttttccac tctcgaaaaa atctgccaag ttttggagtg tcaaccaggt gatttgttga
     1621 cctataaaaa tgactcgaat actataccag aagaataaaa taaagtagaa caaacagtaa
     1681 ataaaaaata atctgaatga tagatgtgtg agacttttag aagttattta cgtctattat
     1741 tcagattttt tatttcgatt gaataccgtt ttatctataa ataagatatg tactgactca
     1801 tacaaagggg gccttttctt ctccatgtac tatcactttt cctgatacaa ctggtttcct
     1861 gttacgttgt agttggatct gcttttagta taatacttta ttcattccac cagactgata
     1921 gcagtttgag cagtctaaat aatcatgtag tattacaggc cattctgttt cataccttga
     1981 agtgcttaaa acttcagcta atggcccatt gtgttaactc ttactccatt cttttttagt
     2041 aagctcccat atatactgta aagccttcta tatattatgt catgttgctt tttaacattt
     2101 actatgtagt tttgataaaa tgatttgaat aacagtgatg gacaattctt ttttattttt
     2161 aacattattt tgataataat gattatttat ttaaaaatac attagataac atttgttacg
     2221 acacgaaaaa gcttcacaaa caaatatcgt tattttaaaa tgagggcgaa ctcacacaat
     2281 taggaggaat agtatgccat ttattgttta cttttttctt tcattactcg tgatctatat
     2341 tccattacca acatttttcc tgctcgtcaa tcgtctagca gagcaacatg atacgattgc
     2401 tgctcttacg aaactttgtt tacttctatt tgtttgtcta gattacttta cgagctatta
     2461 ttggctaaaa cagacaagag taaaaaagag atattatttc ttccttgtct ttttcaatct
     2521 ctttgagttt ctgatccatt gctttttact tcatcagtat catacgatcc atttgtggat
     2581 catctgggtt ttcaaagtgg tcgtattatt ttgtatgttc acctttccta tctcaagaaa
     2641 atttagggag gcattgtttt attaaagaag cttctctgta tcaataaaga cacatttaag
     2701 gaaaaacttt taaaaatcta attgggaatt tgcccgcata aataagaggc tgtgacaaaa
     2761 gtcttgtcac agcctcttat tccgtataaa cagtgttcaa aagcttgcat cttcgataat
     2821 atgcccaacc aaatgaaaaa tatgagaagc tatttttgtt tggctgttct tattacttga
     2881 tgaagaacag ctttttcacg acctcttttt aaaagtcttt ttacagtttt cgagcaaaga
     2941 atgatacgat tagtactaaa atgatggcac caatcaatga tggcacgatt gccattcctg
     3001 caatacttgg tccccaagaa cctaataatg cttgaccaag tgctgatcca actaaacctg
     3061 ctacgacatt tgcaataatc cccatcgaag aacctttatt cgtgattgct cctgcaattg
     3121 ctccgataat tcctccgacg ataagtgacc aaataaatcc catgtttcgt tcctcctaat
     3181 gttttacttc cttattactg aacccgtggt tctgtatttt cttttacttt ttgtgcgccg
     3241 cttccagctg ctgattttac tttatctgtt tgattcgaag caaattcacc ggtttttttc
     3301 gctgcgtcag ttactttgtc ttgcaccgtt tcttgatctt tttcaaattc ttcttttgtt
     3361 ttgatgtcca ctacgttagc gttgacttcg atcacttcta aatgtgtcat attttttact
     3421 tctttgccga ttacttcttg catttcttca aagatttttt cgatatcttt gccatattcc
     3481 acaatgacat ccatatcaac tgctacttgt tttttaccga cttctgtttc gatcccagcc
     3541 gttacattat ctgtattcac aagttttcct gccacattag agaagaaacc accgtttgca
     3601 gataataaac cgtctacttg ttcaattgcg attccgatga ttttttgcac aactttatct
     3661 tcataattca gctcaccgcg cattgaatct tcctgttcag aatcatgctt tccttggtta
     3721 tttgtatgat cagaaccaag ttttccttgt ccgtttgtgt ggtcagaact aagtttttct
     3781 tgtgctttcg catggtcaga aggatgtttt tgctcttcca caggtttaga aggatcgatt
     3841 gcatcatgtt gttctggaac tttagattct ggagttcctg gatgatgagg tgcatgcttt
     3901 tctgcatcat gtttcttctc ttctactcct tgttgaacgt tagggactac tggatctgga
     3961 tgtgcagata ctggtgctgt tttgttcttt tcatcgttca caccatttga ttggtttggt
     4021 gtcgttgggt ctggatgtgc agacactggt ttttggttgt tcattttatt gttattattt
     4081 ttgttattgt tattcatgga tgtttcctcc taagatttaa aatagtgatc taagattttc
     4141 gtttgtttca gataaaaacc gatagcgacg ccgatcgctg ccatgatcaa gatcaataag
     4201 gtcttgaaaa agcccacggt gatccataaa acggctaata tcaatccaag taccccaaag
     4261 atgataggga gcttgtatgt cgaaaatagt tctttcattt ttggtccccc cctattctac
     4321 tcgtttgcgg tcattgcttc gtttagctgg ttcttcaaag cctgtgtatt tcaccgatac
     4381 tttcactggc tcttttgttc ccaatatgtg ttgtacttca ttttcgattt ctttcatcaa
     4441 tgttcctgtt ttaccaatga gtgctgaagt tcgtttcaac tcccctttta cattgacggc
     4501 gatcttgttt ttcgttgctt tgacatttac ttttggtgaa tggatgaatt catcttcatg
     4561 caagtgagaa cgaaccattc cttcaattgc ttttttatcc aacgtcaact ccccatcacc
     4621 atgtttcagt agaaagtttc cgattgtttt tggataaaac aggaaaacaa gtaacgtgat
     4681 aattgtcaaa atagcaaatg caacggcaag ccaaaataca tattgttgca cgtatgaatt
     4741 agtgatggaa aagaatcgaa acttctctag ctgaaaaggc aatggatagg ttgcacttaa
     4801 tagtatcgca aacaaaagca cagatagcaa aagtaatgtt ccgatcactc cgatcgtttt
     4861 tacaccttta ttcattttcg cacctcctca taggggtgaa acgatcaact tcttataagt
     4921 tgatcgcttc tccaccagtt actccgtaaa tttgggctgt aacataactt gctttattcg
     4981 atgctaagaa aacataaact ggtgctaatt ctcctggctg acctgcacgt tctagtaaac
     5041 tttgctgacc aaattcaggg atcgaatcag aaggttgtcc ttcgtctagt tgtaatggtg
     5101 tccagattgg accaggtgct acaccattta cacggattcc tttaggtgca agctgttttg
     5161 ctaaaccgat cgtaaagtta gcgattgaag cttttgttgc tgcgtaatct aataaatgtt
     5221 cgcttggatt gaatgcttga acagaagttg ttgttacgat tgctcctcct gctgggatat
     5281 gcggaacagc ttctttcact aaagcaaaca tagcgatgat gtttatcata aatgtgtctt
     5341 tgacttgctc aagtggtaac tcagcaatag actgacaaga aatttgctgt cctgcgttta
     5401 gtaccatcgt atctagcccg ccaagttcac tcacggcttt atctatgatt tctttaggtg
     5461 cttgttcgtc acgaagatca aaaggtagta agacaatctt acgtcctgca tctttcacgt
     5521 attttgctac ttcctctgca tctttttctt ctcctgggaa gaattgaaga gcgatatctg
     5581 ccccttctct agcaaatgca atcgctgctg cacgaccgat ccctgaatct ccaccagtga
     5641 ttagtacacg gcggttttct agttgattat tgccttcata ggattcttct ccacaatcag
     5701 gaacaggaat catattctgc tgtaaagctg gtgtatcctg atcttgttta ggaaatttct
     5761 ccgtatggta caagtttcgc gggtcgatta attttggttc tgtcattgct gtattcctcc
     5821 tagtttttaa attgtattgc caaaacaaat ttctttgttt gatacctgtt ttaaatagat
     5881 tctttaattt gtataatctt tccggtataa atggtaacct aaaactactg ctgctatcaa
     5941 agagccaaag actacgagta taaagcctag agcagaactt ttacccggta atcctcctgt
     6001 attcattccc caaatccctg cgaacaacgc cggaacggaa atgattaatg cagctgaatc
     6061 tagatatttc atgatatgat ttagattatt gtccatcatc ccgttgaata gatcaccaat
     6121 actctctaat aaatctcgat agatctcgat cattttttct gtttgtcgct gtctcaaatg
     6181 gacatcatag agtagctgtt catcgtctaa acgtttgatg aaagtttcag aattccataa
     6241 ttgatccatt gtttcccgtt gatctcttaa ggtatgatcg atatatacga tgtctctttc
     6301 aagatctgcc tgtttataca gttcttcatt ttccgttgtt ttacgagctg ctttatccaa
     6361 agcgtcaatt cgctttttca tctctcttag ttctttcacg taatgggtgt aaatatctaa
     6421 taatgtatac gtgatgatct tttcaaacga gtttaaatga tttccatgct ttgtcagcag
     6481 ccgatccaca aattcggttt ttctatcgat acaagtaatc aagagattat cggaaagtac
     6541 aaaagatatt ggcgttaatt ttttttcgat acgattatct gactgatcta gattaatcac
     6601 taccaaagaa aatggatgct ctagtttcgt ctcataaagg cgctccatcc gagaaacttc
     6661 ttccggatat tcggttccta cgaaaatatc atcaggaagc tcgaattctt cgattgcttg
     6721 ctcaatctct tcgggctttg cactatcaag tacgagccaa ttatattttt tttcatctgt
     6781 ttctattaca ttcttttctt catccacaaa gtagtatctc aatgtatacc tcctttttgg
     6841 actttctcga aactattagc tgaagaagca gttctttaat ttgatattat aatcgagtac
     6901 tgcgatttca ttttctaatg aaaagctgtc aagctgtttg ttgaagtcca tgttcaatcg
     6961 tttaccgaaa taattttgct ctaatttaga tgtatagatg tccaataatg gatgctcgat
     7021 tttagtcgca tattctccaa attccgaaac aaaaggaatg atttgaaaaa agctgccttt
     7081 tgcaaaagca cctttgtccc ttagaaatgg atcggaatca ttgataagcg cgagtgcgat
     7141 ttttgtattt tccccaacct tttcaattaa cgtctctact gcatttttag acattgtaat
     7201 ttccattcct actccccctc ttcagttgtt gtcttctatt atttaacaac tacatctgtt
     7261 tttggttgaa cttttgcata ttttggatat ttagggaatt tagctacaca acggaaagcc
     7321 gtcatccctg catatttttc gtaatatttc ttcgttggcc cttcaaaatc cttgctccac
     7381 ggtttcacat gtcctgaaaa atggataatg taaggattgt tgcgagtttc ttcgtattca
     7441 cgttcacctg ctgctgttgg atgttttttt gcttttgcca tgatatagcc ttgtgcattc
     7501 caacgcggat gaagtggtaa ccaacggtca tgtaagatag catttaatgc atcttggtca
     7561 tggaatcgta atttttctgg attatgttcg atgaaatcta atactttttg cgtaatattt
     7621 tcatctaacc attttttcac attgatcagc atcaaacctg agttgaaata acgcattgat
     7681 ttagctgaaa ttttcatttt ttccagtcgt tgatggaacc cagcgtcttc aacagctgct
     7741 acgattgaat caccgaagtc aagacgccat aatttagaga tatcttgtaa agcgatcatg
     7801 tcgcaatcca tatataagat acgttcaact tctgtgccgc ggaacaattc cggaatcgca
     7861 atacgataat aagctgtttc tggaatacga tcgctgatta ccacatttgt aaagaattct
     7921 ttattgattt tcaagaattc cacatctgag ttcattcgtg cgtttttcac tgagaagcgt
     7981 aaaagctgtt tactttcaaa atcgatatca tcgtcaatca catagaaccg aacaaattta
     8041 gacgggttgc aattatctaa tactgagaca aataatgcag ctaaatgtgg tacgaatttt
     8101 gtgttacaac ttgcgactac tgctatttct tttttattca ttgatctcgc ctactttcgt
     8161 tagagtactg tgtgctaatt tttttaagta taaattggta tacggatgat ctttcaacgt
     8221 attccaaggt ttatcatgtc ctgtaaagtg aacgatcgaa ggtttttcat ttccttcttt
     8281 atactgacgt tcatattttt catttggtgc tggatgacgt tcaaaaatca gcgaagtctg
     8341 catgttccat tttggatgaa gttgttccca atcttcataa agtacagcat tcaaagcatc
     8401 ttggtcgtga tagatgattc gatcgccatt ttcactgagg taatggatag ttttttctgt
     8461 aatttctttt ttattccatt gatcaatgtc aatcaccatc actcctgaat tgaagtacaa
     8521 gtcatcggaa tcgattccta atctttccaa agctttcact tggcctggat cgataatagc
     8581 gccgattgtt tttccattta acggctcatc atatagtttt acgatatcgt ctagtactaa
     8641 cacatctgaa tctaagtaaa ggactttctt ataatcctct ttagctaata agtttggtaa
     8701 agaaattctt aagtaagcgg tagttgtgat atggtcactg actaggaagt cttcgtagat
     8761 atctttttcc actgtcagga attggatact tgcattactt gaatatttat ttaccgtttc
     8821 ttccaatcct tctttactat attctgatag accatcgtca atcacataaa attttatgcg
     8881 tcttgtttta ttgcaatttt ctaatgcagt tgcgatcatc acgctcaagt aaggagcata
     8941 attttcgtct gaagcagtta ccacaggaac tacgccgtat ctcttctcca tcaaaatcac
     9001 tcctttttct aatctttttc taacctgttc tacatctaga atattcctca tttggtttta
     9061 aagcaaaata tatgctttgt tttcattgaa tattttaaaa tttttttatc acaaaacgca
     9121 tcggtaagcg ctaactattc gtttttcatg gctttttatt caaaggtatt gaccaaaaac
     9181 tactatatat agccaccttt ttcttaagaa tgttttttga aaaaattcat aatgacaaag
     9241 caagttagtt tcattttttt aaattctcat ttaatcttaa ggtaacagga aaatagatat
     9301 gtaaaaagaa agtaggaaga taaaatgaaa ctagcagcga ttgatttaga cggtaccttg
     9361 cttgatcgaa atggaaagat accagaagaa aatatccaag cacttcggaa atttgatgaa
     9421 aatggcggaa tcgtaaccgt cgctaccgga aggaacagca tttctgctaa agatattttt
     9481 tccgaattag gaatcggtgg ctatttgatt tcttccaatg gttcactgat tgctgaaatg
     9541 aaggatggaa aaatggcgaa agttctcaga cgttcaaaaa tagatagcga tacactgaga
     9601 aaagccttct tctatgctca agaagcgaaa atatccatca ttgctagccg agaaacccaa
     9661 gatgatcagc tgacattcga tgaatcaaat ctagtcaaag atgaccctta ttatgaacat
     9721 ttcaatttac agaaccattc ttttgatcaa attttaaata tgttggaaga tccttctctt
     9781 agctatctta aattagcatt aacagataag agtgaagaaa aactacagaa gctacaaaga
     9841 gatctgcaag cagatggtat ccaatcagta ttctctgatc cgcatttctt agaaatcacg
     9901 cctacaggta tcactaaagc tcattcactt gtttttctgg cggattacct tggaatcgaa
     9961 tcgagtgaca tcatggcttt tggcgatcaa gaaaacgaca ttgctatgtt gaattacagc
    10021 gggttgagta ttgcgatggg gaatgcacag cgacaagtaa aagaaattgc aaaccaagta
    10081 acactgacga atgaagaagc tggtgttgct tatattttaa aaaacttcta ttaaaaagaa
    10141 taaaatgacg atatgaatgt aggaggaaag aaaatgttag ttattattga tatgcaaaat
    10201 catattcttg atccaaacag cgaattttat attccagagt cagatcaatt ggcagaacgt
    10261 attgctcaaa gattagctaa agcacgccaa aataatgaat atattctctt cacacgggat
    10321 ataccagttg aactgaagga caaagaagaa gaacgagaag atttgcaatt gatccctctt
    10381 ctttctccac aagaaaatga acgagtgatt aaaaagtatt actttacgat tccacctgaa
    10441 actttagctg aaatccagga aactttattt gaaagcaaag aagaacaaaa agagatcgaa
    10501 gtagtcggga ttgaaacaaa cttgtgtgta ctctctaatc tgataggcct gcagagtgct
    10561 tttcctgaag cagacttttt tgttgatcca atgttagtct ccagtagaaa acacggagaa
    10621 tccgctttag agctgttgaa agatttcaac gtctctatcg tcgaatcata aaaatatcta
    10681 tcttcattta cgatatttaa cacacaataa aaaaagcacg cagaactgtt ttagtcctac
    10741 gtgctttttc tatcaaagta gattggcttt tttatgacac agagtgaaac ggcaggctca
    10801 cgacctcttt cttaaatggt gttcaatcag ctgaccctcg gtattagctt aacaaacggc
    10861 aaaatatgag gaactatttt tccgtttgtt aagctaatac tcaggtcaaa acgctgattt
    10921 cacaacctct tccttaaacg gtattcaaaa gcttgcatct gcagtaataa gaacagccaa
    10981 gtaaaaacat aagaagctgt ttttacttgg ctgttcttat tacttgatgc agggcagctt
    11041 tttcacaacc tcttatgtac cttgtaggac tcgaacctac gaccggacgg ttatgagccg
    11101 tctgctctaa ccaactgagc taaaggtaca tcataaataa aatttatttt tgttactttt
    11161 caactatagc acgaatga
//
LOCUS       DAMEEU010000088        10788 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.089, whole genome shotgun sequence.
ACCESSION   DAMEEU010000088 DAMEEU010000000
VERSION     DAMEEU010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10788
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.089"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..851
                     /locus_tag="PB779_002430"
     CDS             <1..851
                     /locus_tag="PB779_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HDE0739934.1"
                     /translation="LKKKMLIPFDSEVKGLLNKLTISNIDSTREKIIKIFDKINNLFK
                     NDNAELRKGLLEFKLQELELHYSYLVKITEEKEQQKAIKEQMIEEEKVRREIDREKKR
                     IDKEQRQFNSEISKLIAYMQKANADVEKELYANKIQELEEKLKELEVIRENVLQRELN
                     TRAGYVYVISNIGSFGEDIYKIGMTRRLEPMDRIKELSSASVPFEFDVHAMIFSEDAP
                     SLETKLHNHFRKQEVNKINQRKEFFKVSLDEIEKVVLENYNGTVTFTKLAKAEQYRRS
                     LELSKD"
     gene            923..2044
                     /locus_tag="PB779_002431"
     CDS             923..2044
                     /locus_tag="PB779_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0739935.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQDMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNGVS
                     LARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGELI
                     SLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKLIK
                     NNKDKYIFISKNGNPISIQAYNQSLRAVSKELNLDKKVSSHMLRHSHISLLTELGIPL
                     KAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
     gene            complement(2126..3898)
                     /locus_tag="PB779_002432"
     CDS             complement(2126..3898)
                     /locus_tag="PB779_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739936.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
     gene            complement(3901..5613)
                     /locus_tag="PB779_002433"
     CDS             complement(3901..5613)
                     /locus_tag="PB779_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0739937.1"
                     /translation="MKLILRHAKKYKVSVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            5728..6396
                     /locus_tag="PB779_002434"
     CDS             5728..6396
                     /locus_tag="PB779_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HDE0739938.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            complement(6463..7251)
                     /locus_tag="PB779_002435"
     CDS             complement(6463..7251)
                     /locus_tag="PB779_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HDE0739939.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(7334..8806)
                     /locus_tag="PB779_002436"
     CDS             complement(7334..8806)
                     /locus_tag="PB779_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0739940.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            complement(8936..10129)
                     /locus_tag="PB779_002437"
     CDS             complement(8936..10129)
                     /locus_tag="PB779_002437"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HDE0739941.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     regulatory      complement(10127..10206)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            complement(10395..10466)
                     /locus_tag="PB779_002438"
     tRNA            complement(10395..10466)
                     /locus_tag="PB779_002438"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10431..10433),aa:Glu,seq:ttc)
     gene            complement(10478..10551)
                     /locus_tag="PB779_002439"
     tRNA            complement(10478..10551)
                     /locus_tag="PB779_002439"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10515..10517),aa:Ile,seq:gat)
     gene            complement(10564..10634)
                     /locus_tag="PB779_002440"
     tRNA            complement(10564..10634)
                     /locus_tag="PB779_002440"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10600..10602),aa:Gly,seq:tcc)
     gene            complement(10639..10711)
                     /locus_tag="PB779_002441"
     tRNA            complement(10639..10711)
                     /locus_tag="PB779_002441"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10676..10678),aa:Phe,seq:gaa)
     gene            complement(10715..10787)
                     /locus_tag="PB779_002442"
     tRNA            complement(10715..10787)
                     /locus_tag="PB779_002442"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(10752..10754),aa:Asp,seq:gtc)
BASE COUNT         3573 a         2199 c         1793 g         3223 t
ORIGIN      
        1 atttaaagaa aaaaatgctc attccatttg attcagaagt gaaaggatta ctcaataaac
       61 taactatttc taatatagac tcgactaggg aaaaaatcat aaaaatattt gataaaatta
      121 ataatttatt caagaatgac aatgctgaat taaggaaggg tcttttagag tttaaacttc
      181 aagaactaga acttcattac tcttatttag tgaaaattac cgaagaaaaa gaacaacaaa
      241 aagcaataaa agaacagatg atagaagagg aaaaagttcg tagagaaatt gatcgtgaaa
      301 agaaacgtat tgataaagaa caacgtcaat tcaattctga aatttccaaa ttaatcgcat
      361 atatgcaaaa agctaatgca gatgtggaaa aagaattata tgcaaataaa attcaagaac
      421 tggaagaaaa attaaaagaa ttagaagtta tacgtgaaaa tgtattacaa agagaattaa
      481 atactagagc cggttatgtg tatgtaatta gtaatattgg gtcttttggt gaagacatat
      541 ataaaattgg tatgactaga agattagaac ctatggatag aataaaagaa ttgagtagtg
      601 catcggttcc atttgaattt gacgttcatg cgatgatttt ttcagaggac gctccgtctt
      661 tggaaactaa attgcataat cattttagaa aacaagaagt taataaaatt aatcaaagaa
      721 aagaattttt caaagtttca ctagacgaaa tagagaaagt tgttttagaa aattataatg
      781 gaacagtaac atttacaaaa ttagctaaag ctgaacaata tagacgatct ttagaattgt
      841 caaaagatta aatatataaa aagccttcgg gctttttctt ttaacaatta ataggaacgt
      901 atattcgaaa ggaatagaaa taatgtggtt agaaaaaata aatgacaaaa aatttaagta
      961 caccgaacgt tatacggatc ccttaactga aaaaaagaga aaagtgtccg ttactttatc
     1021 tagcaattca cgccaagctt ggaatcaagc taacttactt ttgaatgaaa aaatcgcaga
     1081 aaaaataaaa cgaaatgaag aattaccact aacttttgga gaattaaaaa ctaaatggga
     1141 tgaaaaatac aagccaactg taaaagaaag ttcctatcga acaactcagg tttatctatc
     1201 attaatttca aaatatataa aagatgatgt acttgtaaaa aacgttaata gtaatcttat
     1261 acaagatatg ctagattact actattttga aaaaaattta tcatataatt atgtaataca
     1321 tttaaaaact tttacaggaa tgatttttaa attcgccaac cgtcgatatg gattaaaata
     1381 taatcccgta aatggggttt ctttagcaag aaaacctaag acaaacgaag aaataaaaaa
     1441 agaaaaagat ggttatttat caaaagaaga agttcaaatg attgctagta aacaaaaaag
     1501 ttcacatcaa cagtcacgtt attctttaat tactaaattt ttgtttttaa ctggactacg
     1561 ttatggtgaa ttgatatctt tgactgaatc tgattatgat ggtaataaaa ttacggtttc
     1621 tggtacttat gattacgagt taaaaattaa aacaacaact aaaaatacag gttcttatag
     1681 aaccattgaa ttatcaagta atgctaaaga aatcatagat caattaattg aagaaaacaa
     1741 attaattaag aataataaag ataaatacat tttcatctct aaaaatggta acccgatatc
     1801 tattcaagca tataatcaat ctttaagagc agtatccaaa gaattaaacc tagataaaaa
     1861 agtttcttct cacatgttaa ggcattccca catttctcta cttacagaat taggaatccc
     1921 attaaaagcc attatggatc gtgtaggaca tgaagattca aaaacaacat taaagattta
     1981 tactcataca actaaaaata tgcaaaatca actagtagaa aaactaggaa aaatagaaat
     2041 ttaaattgcc ccttttctgc cccttataaa aacaaacaac ataaaatata taaaaagaac
     2101 cccgttataa cgaggttctt ttaatttaac tttcaaatac aaattgatta tgataaagtt
     2161 ccgcataaaa tccattttct gctaataact catgatgact gccttcttca atgacttccc
     2221 catcacgcaa gacaacgatt ctatctgcat tcaagattgt tttcagccgg tgagcaatca
     2281 caaagctggt tcttcctttg attgcttcat ccattgcttt ttggatcctt gcttctgtta
     2341 ccgtgtctac attacttgtt gcttcatcca aaatcaataa agatggattt gtgatgatcg
     2401 ttcgagcaat actgatcaac tgcttttgac ctgtactgaa taagttattt tcttcggata
     2461 tctctgtatc ataacctttt tctaacgtca tgatgaagtc atgaatattc gcttgttttg
     2521 ctgcattgat gacttcttca tctgaagcgt ccggtttgcc gaatgtgata ttgtctttga
     2581 tcgttccgga gaacaataca gattcttgca aaacgattcc tacatgtcta cgtaatgcat
     2641 caagatcata atctcggata tctattccat cgatgactac tgaaccatca ttgacatcgt
     2701 aaaaacggtt tagcagattc atgatcgtcg ttttccccga tcctgttgga ccaacaagag
     2761 caaccatttc tcctttgtcc acattgatcg agacatcttt caagactagt ttttctggag
     2821 aataaccaaa atctacgtgc tgcaacgcaa gacctttttc aacaccatca aatgctttac
     2881 cgttttctgg tttgacttca tctttttcat caaatatttc attcaatcgt cttgcccctg
     2941 taatcgctaa ttggatcatg ctgtatccag atgaaatctg catcagtggt tggtaatatt
     3001 gttgtgaata ctggacgaat gtcacaacta agcctaatgc caccgaacgt tccaaatcac
     3061 catttaatgc taaccagccg ccgaaaaaga taactatcgc tgtattgacc agtgacattc
     3121 cttgcatcat cggaaatagt agaccagaat aagcttgtcc tttgaaggtt gcttcgcgaa
     3181 cactttgatt atgctctaag aatccttcaa tcgtttcttc ttgtaagcca tttgtgatga
     3241 tgacacgttg tccgctgatt ttttcatcca tataaccatt tagtttcccc acttcatctt
     3301 gctgaagatc cacatatttc cgtgctttgc ggataatcaa gacagctatc aaaacggcta
     3361 ctggagtgga agcaattgta gcccaagcta actctacatt ttggcggaac atcatgatca
     3421 agatcccgac aagtaaaaca gcattcgtga tgacttgaag caaagcttgg ttcaaactat
     3481 tttgaatatt atctaagtca ctggtaaaac gacttaaaat ttcaccgtct tgatgagaat
     3541 caaagaaacg gatcgtcaat ttttccaatt tgttgaatag accgatacgc attcggttcg
     3601 ttgacttccc tactacttgt gtgaacaaaa tactatagat aaagttggct gcactagcta
     3661 gtacataaaa cagcaagagt ttccatatta cagaaacaaa tttgctttta tcgtctacgc
     3721 cttgcatcaa gcctcctacg taattagcta attcttgaaa agcttccccg atgtattgag
     3781 gtgcctttac ttgtagatag gtagcaatga tcactgtgat aaagataaag aaaaaggaga
     3841 gtttgtaccg cttcaaatag tgatagaaaa atttacttgc ttttattaga tcagtcatac
     3901 ttactcctcc gttccttttt gagtttcaaa gatttcctga tagacacggt ttccagctac
     3961 caattcctca tgggttcctt cgccgactaa tctgccttca tccaatacta agatgcggtc
     4021 tgctttgaca acagaagcaa ttttttgtgc gatgacaatc gtcgttgttc ccttcaaatc
     4081 tcgatcgagt gcttctcgga ccagcttttc agagcgagca tccagtgcac tcgtactgtc
     4141 atctaggatc aagatctttg gattaccgat aacgccacga gtaatggata aacgttgctt
     4201 ttgaccacca gaaaagttac tgctacgttc ttctattggt gcttcgtaac gatcagataa
     4261 cttttcgatg aattcttttg cttgagcaat agaagaagca tgttccatct ctttttctgt
     4321 tgcattcttt ttcccttggc gcaagttttg agcaatcgtt cctgagaata aaattgcttt
     4381 ttgcaaaaca aaggaaaccg tttgtcttaa actcttttca tttacttgac gaagatctac
     4441 accacctact tcaactttgc cttctgtcgg atcaaataga cgagggatca attgtgctag
     4501 tgttgacttc ccggcaccag tcgccccgac gataccaacc atttctccag gtttgataga
     4561 aaagctgata tctttaagcg tatctgtatc ctcaccagga taacgaaaag aaacatggtc
     4621 aaaagtgaca gaacccgtca actcttgttc tggaacgtct aaataagtaa gatctggttc
     4681 agcatctaaa atttccgcaa tccgcttcag cgatacggct gctcttgaag tcatcatcat
     4741 catcattccg ccaataatga ttgccatcat aatctgcatc aagtagttca tgaatgaagc
     4801 aattccacca attaacgtag gatcatcttt aacaagatcg ctcacaaaaa agatcgcccc
     4861 aaccacagcc aaattggcag ccagcatgaa ggacgggatc atcacagaaa ataatgtacc
     4921 gactatgatg ttgtgttttg ttaagtcctc acttactttg ctgaatgact tcaattggtt
     4981 ttcttcttgt acaaaagatt tcactacacg aatccctagt aagttttctt ttgcaatgct
     5041 attcacacga tcaatcagtt tttgaatgat catgaagtgc ttgcccatcc ttgtaaatga
     5101 aagtgccgta atcagaaata ccgtaacgat aagcgctacg atgatccacc ataattgcgg
     5161 catcgtgatc atagctaaaa tgaaggcacc aataaataag aatggaattc gaaaaagtga
     5221 ttgcaaagaa atcatcacta aattttggat ttgcgtgata tcatttgtta gacgaacaac
     5281 aagatttcca gcagagaact gttcgatatt tccaaatgaa aatgtctgga tctttcgaaa
     5341 tgcttcttct cggatatctg cacttacgcc ttgagctact tttgcagaga aaatcgtgtt
     5401 cgttacacct gcggctaatc ctagcaaagc cagactgatc aggtaaatac caattgtttt
     5461 catttcatca ttatcttctg taataatagc ttccaatact tgctgtagta acttaggttg
     5521 ccataatgct gctgcaacca tgactgctac ggacagcaag gaaataaaaa cagatacttt
     5581 atattttttc gcatgtcgta agattaattt cattcgttga ttacacccct ttgtttaaat
     5641 tgacaggact aatttaacac tgtaaaatta gaccgactaa caatttacca tgtttaaaaa
     5701 gataatgcaa tacacgaggt tgataaaatg gaaataaagc tttctcaagc aatcatcatt
     5761 caggccgcct ttgatatcct ggctgaaaca caagctcttt cgcagctttc catgcgaaac
     5821 atcgcaaaca gaattcatgt tcaagcacct gctttatatt ggtatttcaa aaacaaacaa
     5881 cagctcttgc aaaaaatggc tgaaacaatg gaagaagaat tagcgcttcc agatccaact
     5941 ttgccttgga atgaacagtt gctgcagtat atggaaaatt actatgacct ttatacacgt
     6001 ttcccttgtg gggcagaatt agaaatcaat actgtgcccg cttttccgag tcgattagaa
     6061 catttggagc aaatgatcca attacttgtt cgtgaaggat tttcagtcac ccaaagtcat
     6121 caggccattg cctctctcca caatttattg attggacagt taatggatca gcagcatgaa
     6181 cagcagcttc gacaaaaaat tatggacgga aatgaatttt tgaaagaaac agttctattt
     6241 atgcgtaatt atgtagttga aaatcaatta gagggattta aagaaagtat gcagtcccat
     6301 gcagaattga atgaaaaagc actctttcta acgagtgcac aaacctatat tgaaggctta
     6361 tgccaacaaa ataaaagaag agaaaacgag cagtaaaaaa gctcctatag agatcactat
     6421 gtttgtgatc tctataggag ctatcttttt aagactcttt ttttattttt cttccattag
     6481 ccacgccaat gcacgttgaa tccattggtc ccagaagatc cagttatgat cgccaggtcc
     6541 ttgttcaaag gtgaccgcca agccttgttc ctgcatagca gataccattt cctgatttgc
     6601 ctgataaaga aaatcagatt ccccacaagc catataaaat cttggaactg gttttccgct
     6661 ttttactagt tctttcaata agtattgcgg atcatttttt gaaccttcga tttgatccaa
     6721 tggtccaaag atcccttccc aaaaagatgc tttacgaacc atcaaaagat catccattcg
     6781 atttcctaca gaaacagcgc ctgaaagaga gattactgct gcgaaatttt ctgattttgc
     6841 aaggcctagt tttaacgcgc catatccgcc catcgataat ccagcggcat atgttttttc
     6901 tctttttctt gttaattgcg ggaataattc atgacaaatc tcaggtagct cttctgcaat
     6961 gaatgtccaa tacttcatgt cataaactgt atctgtgtac cagccaagat cagtagatgg
     7021 catgatgaca gctaatccgt agtttgctac ataacgttca atcgacgtac gtctttccca
     7081 tacactatga ttgccaccca ttccatgaag taaatataaa acaggtatat ccgttgtctc
     7141 ttgctctgaa ctggtgccaa tcaccttttt tgttgtttgc ggtagtatca catttagatt
     7201 gacttccatt tctaacacat tcgaataaat atttgcttga ataaatgcca tattttcgcc
     7261 ttccttagta agaagttatt tttgaataac tttaaatttg aatgattcgg ctacgtacat
     7321 atcttaaccg aaactactgt tttattttac cacttttttc atgaacgaaa agcgttaaga
     7381 ccaaagcaat gatcacgagt aacaagccaa ctagataaac ggaatgtaac ccatcataaa
     7441 gaatttttct taatggtaac aaaatatccg catcaatata tttagccgtt tgtggattca
     7501 ccagtttatt catgatatct gcatcatttg ttaaatttgc tgctgcaagt tctcgtttag
     7561 ttaccccatt tatcaataaa ccaaaaatag aaaccatgac tgtttgacca attgttcgaa
     7621 ctaacgtatt aaaagaagtt gctacaccaa gctggtcacg agatacacta ttttgtgcac
     7681 tgacagtcga ggtagtcatg gtcacaccta agcctatacc gatgaccgtt gatatagcaa
     7741 aaaaccataa atagttactt ctgaaaggca taagatacaa ccaagcgccc ccaatagctg
     7801 cgattagtag tccaattctc aagacccaat gagttttcat ttgagtcatc cacttgcttg
     7861 caaggaaaga accgaccatc cagactagtg ataatggtgc taataccagc ccaccaattg
     7921 ctgcattcag ccctaataca ccttgcatcc acatagggat ataaacatcg attcccatca
     7981 aaaaaccact agccaatgct gcagccaagt tgaccacaac aaatagtgga tttttgaata
     8041 aatgcatcat gatgacagga tctttagctc ttttttcggc aaaaacaaaa atacctaaca
     8101 ttacgatact acctagcagc aaagcagaaa caagcggact cattccttcg tctcctaata
     8161 attggaaccc taacagcaat gagacaagca tggccatcaa actaaaacta ccaaaaatat
     8221 ccattggttt agactcatgt atgatttttg gttcatttaa atatagccaa atcaaaataa
     8281 ttaatagaat tccgatcggc acattgataa aaaagatcca gtgccagctg atcgtttcaa
     8341 cgatgaatcc tcccgcaagc ggtccaaaaa cactggcaat cccccaggct gaactattca
     8401 aacctaaaac ttttgctcgc ttttcaatag aataaagatc gccgatgatc gtcaaagcta
     8461 ctggcatcat tgccccagca cccatccctt gaatcgcacg agcagcaatc aacccaatca
     8521 tgctttgaga taaaccgcaa aataacgaac cgataataaa caataatgtc ccaaaaataa
     8581 agattggttt ccgtcccact ttatccgcaa gttttccgta aatcggagta agcatagcgt
     8641 ttgtcagcaa ataaatcgaa aatacccagt tcatgatttc cattccatgt aatgaaccga
     8701 caatcgttgg catagcggtt gttacgattg taccttcaat agccgtcatg aacgttgcaa
     8761 tgaaaatact cactgtgacc aaagtaacat ttgtttcttt tttcatctta ttcctccctt
     8821 tcattatgac aggatctaaa aatagataaa taattactat ctttttcaag aggttaactg
     8881 ccataaaaaa agctggaaca accaccactt ggcgatcgtt ccagctgaat ataacttatt
     8941 ttgctaaact tgctttcaac gcatctactt tgtccgtatg ttcccaaggc aaatctacat
     9001 ctgtacgacc aaaatgaccg taagcagctg tttgtttgta aatcggacga cgcaaatcaa
     9061 gcatctcgat gattcctgct ggccgaagat cgaagttttc tctcactgca gcaatcagtt
     9121 cttcttccgg aaccgttcca gtaccgaaag tattgattga gatcgaaaca ggttgagcaa
     9181 caccaatcgc ataagctagc tgtacttctg ctttgcgagc aagccctgct gcaacaatgt
     9241 ttttagcaat ataacgtgca gcatagctgg cagaacggtc aacttttgtc gcatctttac
     9301 cagaaaaagc accgccacca tgacgagcat aaccgccata cgtatcaaca atgatttttc
     9361 ttcctgttaa tccggcatcc ccttgaggac caccaatgac aaatcggcca gtcggattga
     9421 tataatattt cgtttgatca tctaataatt cagctggaat aacttccttc actacttttt
     9481 cgatgacatc atgacgaatt gtttcattat ctactgcatc atcatgctgt gttgaaataa
     9541 cgattgtatc tacgcgttcc ggttgtcctt gatcatcata ttcaaccgtt acttgagatt
     9601 ttgcatctgg acgtaaatac gttaattcat ttgatttacg caaatctgcc aagcgtcgta
     9661 ccagacgatg actcaaagcg attggtaaag gcatcaattc tggtgtttca tctacagcaa
     9721 acccaaacat taaaccttgg tcaccagcac caatctcatc taatacgtct tttttatctt
     9781 catcccggat ctcaagtgct tcatcaactc cttgagcaat atcaggagat tgttcatcaa
     9841 tcgcaaccaa tacagctgct gtatctccat caaatccgaa ttttgcacgt gtataaccaa
     9901 tttcttttat tgtttcccgt acgacttttt gaatatctac atatgccgtc gtagatattt
     9961 ctccaaatac taaaacaaga ccagttgtta cagacgtttc acacgctact cgtgctgttg
    10021 gatcttgttt taaaattgca tccaagattg catcactgat ttggtcagca attttatctg
    10081 gatgtccttc agaaacagat tctgatgtaa ataagtgtct ttctaccatt ataatgattc
    10141 cccctagtta aattcggtta caaggcatct ccgtcctgcg gatcctttcg ggaacttgca
    10201 acgaaccaag tatagcagat aaaacagttt tctgctcgta ttttttcatt tttttgctta
    10261 aaaaatataa aaatatttta cattagaact gtccaaaaaa gcttagcaca atcatccata
    10321 aagataactc tgctaagctt tttaaaatca ttctttcaga taaaaagaaa aagatactca
    10381 aaaagtatct tccatgaccc gtacgggatt cgaacccgtg ttaccgccgt gaaagggcgg
    10441 tgtcttaacc gcttgaccaa cgggccaata aaataaatgg gcctaaatgg actcgaacca
    10501 tcgacctcac gcttatcagg cgtgcgctct aaccagctga gctataggcc cataaaaact
    10561 aaaagcgggt gacgagaatc gaactcgcga caacagcttg gaaggctgtg gttttaccac
    10621 taaactacac ccgcataatg gcgcgggaca gaatcgaact gccgacacat ggagcttcaa
    10681 tccattgctc taccaactga gctaccgagc caaacggttc cgacgggaat cgaacccgcg
    10741 atctcctgcg tgacaggcag gcatgttaac ccctacacca cggaacca
//
LOCUS       DAMEEU010000089        10383 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.090, whole genome shotgun sequence.
ACCESSION   DAMEEU010000089 DAMEEU010000000
VERSION     DAMEEU010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10383)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10383)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10383
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.090"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            6..305
                     /locus_tag="PB779_002443"
     CDS             6..305
                     /locus_tag="PB779_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739942.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="PB779_002444"
     CDS             378..1739
                     /locus_tag="PB779_002444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HDE0739943.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="PB779_002445"
     CDS             1761..2021
                     /locus_tag="PB779_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739944.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="PB779_002446"
     CDS             2035..2787
                     /locus_tag="PB779_002446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HDE0739945.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIIDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="PB779_002447"
     CDS             complement(2881..3486)
                     /locus_tag="PB779_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HDE0739946.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="PB779_002448"
     CDS             complement(3539..4513)
                     /locus_tag="PB779_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HDE0739947.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="PB779_002449"
     CDS             complement(4891..5610)
                     /locus_tag="PB779_002449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739948.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="PB779_002450"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="PB779_002450"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HDE0739949.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="PB779_002451"
     CDS             7161..8558
                     /locus_tag="PB779_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0739950.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="PB779_002452"
     CDS             8639..9079
                     /locus_tag="PB779_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDE0739951.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="PB779_002453"
     CDS             9227..9553
                     /locus_tag="PB779_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDE0739952.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="PB779_002454"
     CDS             9554..10303
                     /locus_tag="PB779_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739953.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
BASE COUNT         3291 a         1832 c         2150 g         3110 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcat tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttt
//
LOCUS       DAMEEU010000090        10217 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.092, whole genome shotgun sequence.
ACCESSION   DAMEEU010000090 DAMEEU010000000
VERSION     DAMEEU010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10217)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10217)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10217
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.092"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(53..826)
                     /locus_tag="PB779_002455"
                     /pseudo
     CDS             complement(53..826)
                     /locus_tag="PB779_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            847..2049
                     /locus_tag="PB779_002456"
     CDS             847..2049
                     /locus_tag="PB779_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
                     /protein_id="HDE0739954.1"
                     /translation="MCTKLLQNTAHKNPYKTVDEATQLDLVIVVNQLLTGYDSKWVNT
                     LYLDKSLEYQNIIQAFSRTNRLNGPEKPFGTIRYYRKAHTMEQNIEEAIELYSGKQAK
                     GLFVEKLYNNLEKLNDIFEEIKSVFNISGIENFSHLPEVPGEIKQFVNLYNQLIHCYE
                     SAMIQGFTWAKSTYEIQDYEPITVVITEYEFNILAQRYSEIEREPRDGNDSIAYDIDY
                     QLPEGSRSRINYEYLNTNFKKYMNIKEERDSNLIQSLLNDLHRTFAQLPVELQPYAEM
                     ILNDVNNGELVIKEGWEFTDYLNEYQLSEEDDFIQDLVDSTNINEALLREMLDLRLTE
                     VNINEYSRFDKLKSSVNVGHFSGYIEKNLGKMVIPIKVNMLIDRLLRAFLLEDVFDVT
                     EYIKNYFN"
     gene            2782..3750
                     /locus_tag="PB779_002457"
     CDS             2782..3750
                     /locus_tag="PB779_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0739955.1"
                     /translation="MDVAKTVNAIVEKNDGEISGIYLVACGGSLVDMYVSDYFLKAEA
                     SKCITGLYTANEFNHVTPKQLDDKSVVILCSHGGNTAETVKAGEVAQARGAVTVGLTH
                     NKTADLLKVSDHSFLYEWGDDAKIVNNPMAIILDLTVSLVNVTETFEHYGKFREGMKV
                     IDTVIENGIKQVQDRIKVFADKYKDETMFYILGSGPSYGHAYGFSICSLMEMQWLDST
                     SVHSGEFFHGPFEVTDKDTNFILLMSIGRTRALDERAKRFLDKYAERVEIVDAKELGL
                     DMISDEVSEFFNPILFYSILSEYRSALADARNHDLDVRRYMGKVEY"
     gene            3761..4576
                     /locus_tag="PB779_002458"
     CDS             3761..4576
                     /locus_tag="PB779_002458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructoselysine 6-kinase"
                     /protein_id="HDE0739956.1"
                     /translation="MKVLGLGDNVVDKYENLGIMYPGGNSLNFAVFAKKLGHESSFMG
                     VFGSDEEAAHVLSAIKKIGLDNSHSRFEKGENGCARVKIDEGDRIFLGSNSGGVTREY
                     PIQLTEEDREYLNQFELIHMGLYSHVNHLLEELQNVSGKISYDFSDDFTEEEVQRAID
                     KVDFGFFSIEDFSDEEVKQFLMKHFCERNDVLIATRGEKTAIGYDGAKFYEVNPVLEE
                     PVDTMAAGDSFLTAFLLYFLEGDDIVTAMKKGNEFAGKSCLVDGSFGFGIHYD"
     gene            4644..5354
                     /locus_tag="PB779_002459"
     CDS             4644..5354
                     /locus_tag="PB779_002459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0739957.1"
                     /translation="MLDTNAQLPLYLQLKEILKNKINTGEYPENTKIPAESELIESYE
                     VSRITVRKAVEELVEEGYLLKKQGKGTFVNRHKVFRKIEYVMGFSESCKSNGFTPTSI
                     VLERKIIPATEGMAKKLDIAQGDDVLYIQRKRMADNIPIMLENNYFSYERYSFLMEEE
                     LTDSLYEVLKVQGTLAINPGETALEIVTADDQIAKIMEVAVGTPFFFMDTLINDQNNI
                     PIHVGNQYYLGEVYRFYL"
     gene            5390..6631
                     /locus_tag="PB779_002460"
     CDS             5390..6631
                     /locus_tag="PB779_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HDE0739958.1"
                     /translation="MKQVLRSKMIFDGEQPPFKGYIVINEGIIEKVENNWNYSDLLNE
                     NTELIAYDDQFVMPAIHDNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKAD
                     EPIYAHGWDAALWKTDPSEELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKET
                     SAESRVLLIKEMLANKKLLAEVYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKIL
                     SNLYVQAVQEPLQHELLYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQSGVA
                     SPEIDYEAIKAEVAAFNEVEIPCCLTTEGDKAGYKAASILVEFGKRLPEGVFNSISDL
                     EMVTQKTAEKMNEGQVVAEVYPQILGLNQTLEEAYMSTVIKNESSPQSCVKVQPHQKH
                     NVLRCEPNCHAFLSEERGQEQ"
     gene            complement(6689..7876)
                     /locus_tag="PB779_002461"
     CDS             complement(6689..7876)
                     /locus_tag="PB779_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HDE0739959.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
     gene            7986..8363
                     /locus_tag="PB779_002462"
                     /pseudo
     CDS             7986..8363
                     /locus_tag="PB779_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336725.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
     gene            8411..9811
                     /gene="yfcC"
                     /locus_tag="PB779_002463"
     CDS             8411..9811
                     /gene="yfcC"
                     /locus_tag="PB779_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HDE0739960.1"
                     /translation="METMKRKFTFPHSYTLIFILIILAAILTWIIPSGQFETVVENVA
                     GMEKTTVVPGTYHQIDKADYGQGFSSILMAPAEGIISAVEVVAFVLIVGGAFGIILKT
                     GAIDRGLFTLAKVLGDKGILVIPMSMILFSLGGSTFGMSEEVIPLFAVFISLMFSLGY
                     DSMTAILILFLSTQAGYVGSTINPFNVLIAQGVAGVYGNPLLWFRMLSWIVITGISIV
                     FTMLYASRVKKNPLSSIVYESDLKVKHKFQNFDTEKEFSTQDKLIIAGFIVGLGIMIW
                     GIISKGWYMVEISALFLGLGLFAGGIARFSQKEIAEAFVEGCSDFAYAAVIIGLARGV
                     LVILEGGMIIDTILNSLANLLGGLPKFLFTTILLISQVIVSFFVPSSSGAAALTMPVM
                     APLGDLMNVSRDVVVLSNQFGNGLMNIISPTSGVLLAGLAIAEINFSKWFKVGFKIFA
                     ILTLVSAVLLYIATLF"
     gene            9844..10011
                     /locus_tag="PB779_002464"
     CDS             9844..10011
                     /locus_tag="PB779_002464"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739961.1"
                     /translation="MIKINQLAGMNIHYLFYSLKEFFAYQQKIGISSVELWGGAPHFF
                     IDAFTGSVAKF"
     gene            10065..>10217
                     /locus_tag="PB779_002465"
     CDS             10065..>10217
                     /locus_tag="PB779_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDE0739962.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVREILYDRGINVSH
                     TTIYRWV"
BASE COUNT         3253 a         1690 c         2069 g         3205 t
ORIGIN      
        1 gccaataaaa cttagtccga tatgcggcgc gttctgtgcg ccgcatattt ttttagtttt
       61 caaagatcag accttgttgt aaatagatcc gtgcccgaaa gttataaaag ttgcgataac
      121 caaacgcaat tcgtttaatc agcttgatct tgttatacag cccctcagtg acgccgtttg
      181 agtgggacac cttaaaggca tttgaaatac ccgattggta gcgatggaag atcgtgaatt
      241 tctttttaaa cgactgaggt aacgtagatg aaattgtttt aagggtttct tgaaagccta
      301 ccgtatctcg tttaacgaaa taatagcgta ataattgaca aaaatgatac gcagttcgca
      361 attcttcgtt gtagcttaac agctcattaa cgatttctgt ttgactaatt ggtcgtttaa
      421 acagtcgatg ataatgccgt ttgagtgcct cccatgtcgt ggaatctttg agtaagagtt
      481 tccaatatcg cttgagccga cggtacttct tctgattttc agagtgtgag gttcgaaaac
      541 gattcatgat ctggacacgt aattgattga agctgcgatt gatgtgttgg acaatatgaa
      601 agcggtcagt tacgatctcc gcatttggaa agaccgtttt aagcaactga caatagctgg
      661 cattcatgtc catcactagg tacttgacct ttaaacgggc ctttctagga aagcgcagga
      721 agtattgagt tagtttgtaa agtctgcgat cttcaagggt cgtaaatagc tgattggttg
      781 tcccatcaac acaaataaaa ctcatggaac cagaagtggc aacattgtgt acttttcttt
      841 gcaatcttgt gtacaaaact attgcaaaac acagcgcata agaatcctta caaaacagta
      901 gatgaagcaa cccaattaga tcttgttata gttgttaatc agctcttaac gggttacgat
      961 tcaaaatggg tcaacaccct atacttagat aagtcacttg aatatcagaa cataattcag
     1021 gctttttcac gcacaaatcg tcttaatggt cctgaaaaac cgttcggaac cattcgttat
     1081 tatcgtaaag cacatacgat ggaacagaac attgaagagg ctattgagtt atactcaggc
     1141 aaacaagcaa aagggttatt tgttgaaaaa ttatataata acttagaaaa gttgaacgat
     1201 atattcgaag aaattaagtc cgtatttaat atttctggca tagaaaactt cagtcattta
     1261 ccggaggttc caggggaaat taagcaattt gtaaatcttt ataatcaact aatccattgt
     1321 tatgaatcag cgatgataca gggattcaca tgggcaaaat cgacttatga aatccaggat
     1381 tatgaaccta taacagtagt aatcacagaa tatgaattta atatcttggc acaacgttac
     1441 agcgagatag agagagaacc tagagacgga aatgatagta tagcgtatga cattgattac
     1501 caattacctg aaggtagtcg tagtcgtatt aattatgagt atttaaacac aaacttcaaa
     1561 aaatacatga atataaaaga agaacgtgat tcgaatttaa ttcaatcatt gttaaacgac
     1621 ttacatcgca catttgcgca attaccagtg gagttacagc catatgctga gatgattcta
     1681 aatgatgtaa ataatgggga attagttatc aaagaaggat gggaatttac tgattacctc
     1741 aatgaatatc agcttagtga agaggacgat tttatccaag atttagtgga ttcaaccaat
     1801 attaatgagg cattattacg tgagatgttg gatttacgct taaccgaggt aaacattaat
     1861 gaatatagtc gatttgataa attaaaatca agtgttaacg taggtcattt cagtggatat
     1921 atcgagaaaa atttaggtaa aatggtaata ccaatcaagg taaatatgct aattgacaga
     1981 ttattgcgtg catttttatt agaagatgta ttcgatgtta cagagtacat aaagaattac
     2041 tttaactaga gtacacctac atcttatagt acataaaaaa attcatcttt tttagtttaa
     2101 taattcacca aaaaggtgag taatgccatt tttgaaaatt gagcttgttt tatgtctaca
     2161 tctgtatccg tatataatcc aaaggattat aaactcagaa gagtctttat tttttctgaa
     2221 tataactact gtatcaaaaa caatcgatta tgagacaaaa caaaatgacc tcttttattt
     2281 aagaaaggag gtcatttttt gtatcataaa ttgtattaaa atcaatgtat cactttttaa
     2341 tcaattttaa gaccataaat tgcgtactaa aagaaattct gcaattcaaa ataaagcatt
     2401 ttaagccatt ttcaaattta agtgcaccca tctacccgtc aaatcacttt attttccact
     2461 ccagtagttt cctaattcaa ctgtgtgcaa aacgatttct tctaaacaaa tcaagacaaa
     2521 cttataaacc ttcatcccag caccataatt atttaaatca taggcatttt tcgaaattag
     2581 tatatgtact caagtttcac tgcagattat ttatattttt tagagaaata aatttttcct
     2641 attgacaaac acaaagaaag cggatacaat acaattatgt cacatgacgt tatatgacgt
     2701 tatgtaatat ctttacattt aatcagttac ttttattttg gataaaatta acatttttaa
     2761 aattttaagg aggaaatgtt gatggatgta gcaaaaacgg ttaacgcaat tgtagaaaaa
     2821 aatgatggag agatttctgg aatttatttg gtggcttgtg gcggttcgct ggtagatatg
     2881 tatgtctcag attattttct taaagccgaa gcatcgaagt gtattacagg cttatataca
     2941 gcgaacgaat ttaaccatgt aaccccaaag caattagatg ataaatctgt tgtcattcta
     3001 tgttctcatg gaggaaatac agcagaaacg gtaaaagcag gagaagtcgc tcaagctaga
     3061 ggagctgtga ctgttggtct gactcataat aaaactgcgg atttattaaa ggtttctgat
     3121 catagtttcc tttacgaatg gggagatgat gcaaaaatag tcaataatcc tatggccatc
     3181 attcttgatt taactgtatc tttggtcaat gttaccgaaa catttgaaca ttacggtaaa
     3241 ttcagagaag gcatgaaggt tatcgatacc gtaattgaaa atggcattaa gcaggtgcag
     3301 gatcgtatta aagtgtttgc tgataagtac aaagatgaaa caatgtttta tatcttaggt
     3361 agtggaccat catatggaca tgcttatggt ttttcaattt gctctttgat ggaaatgcaa
     3421 tggcttgatt caacttctgt tcattctgga gaattcttcc atggaccttt tgaagtaaca
     3481 gacaaagata cgaattttat tctcttgatg agcattggac gcactcgtgc tttagatgaa
     3541 cgggcaaaac gattccttga taaatatgca gaaagagtag aaatcgttga tgcaaaggaa
     3601 ctaggattgg atatgatatc agatgaagtt tctgaattct tcaatcccat tttattctac
     3661 agtattcttt cagaatatcg ttcagcttta gcagatgcac gcaatcatga tttagatgtt
     3721 cgtcgctata tggggaaagt ggagtactag gaggattaaa atgaaggtat taggcttagg
     3781 tgataacgtc gtcgataaat atgaaaatct gggaattatg tatcctggag gaaattcatt
     3841 gaattttgca gtttttgcaa aaaaactggg acatgaaagt agctttatgg gagtttttgg
     3901 ctcagatgag gaggcagctc atgttttatc agcaataaaa aaaataggac tggacaacag
     3961 tcactctcgc tttgaaaaag gcgagaatgg ctgtgccaga gtgaagattg atgagggcga
     4021 ccggattttc cttggcagca attcgggagg tgttactcgt gaatacccga ttcagcttac
     4081 tgaagaagac agagaatatt taaaccagtt tgaattgatt catatgggat tatatagcca
     4141 tgtcaatcat ctattagaag agttacaaaa tgtttctgga aagatttctt atgatttttc
     4201 tgacgacttt acggaagaag aggttcagcg ggcaattgat aaagttgatt ttggcttctt
     4261 ttctatagaa gacttttccg atgaagaagt aaagcagttt ttgatgaagc atttttgtga
     4321 gcgaaatgat gtattgattg caacccgagg agaaaaaacg gctattggtt atgatggagc
     4381 aaagttttat gaagtgaacc ccgtgctaga agaaccagtt gatacaatgg cagcgggaga
     4441 ttctttctta acagctttcc tactttattt tctcgaaggg gacgatatag tcaccgcgat
     4501 gaaaaagggg aatgaatttg ctgggaagtc ttgtctggtt gacggttcgt tcggctttgg
     4561 tattcattac gattgagctt gttttaaatt cctgcatttg ataacctaaa gaaagaaatc
     4621 ccggtaaagt ggaggttaaa aaaatgctgg atacaaatgc acaattacca ttgtacttac
     4681 aattaaaaga aatattaaaa aataaaatca atacagggga gtatcccgag aatacgaaaa
     4741 ttcccgctga atcagagctg atagaaagtt atgaggtcag ccgaatcaca gtgagaaaag
     4801 cagtagaaga actggtagaa gaagggtacc tacttaaaaa acaagggaaa ggaacttttg
     4861 tcaaccggca taaagttttt cgtaaaattg aatatgttat gggtttcagt gagagttgta
     4921 aatctaatgg ttttacaccg actagcattg ttttggaacg caagatcatt ccagcaactg
     4981 aagggatggc aaaaaaactc gatatcgctc aaggtgatga tgttttatat atccagagaa
     5041 agcgaatggc ggataacatc cccattatgt tagaaaacaa ttatttttct tatgaaagat
     5101 atagtttctt aatggaggaa gagctgactg attctttgta tgaagtactt aaagtccaag
     5161 gtaccttagc catcaatcct ggggaaactg cacttgaaat tgtcacagct gatgaccaaa
     5221 ttgccaaaat aatggaagta gctgttggga cgcccttttt ctttatggat actttaatca
     5281 acgatcaaaa caacatacca attcatgtag gtaatcaata ttacctggga gaagtatatc
     5341 gtttttactt atgatttcct gttttgattt caaggagtag attttattta tgaagcaagt
     5401 attgcggtca aaaatgattt ttgatggaga gcagccacct ttcaaaggtt atattgtaat
     5461 caatgaaggg atcattgaaa aggtggaaaa caactggaat tacagtgatc tattaaatga
     5521 aaacacggaa ttaattgctt atgatgatca attcgttatg ccagcaattc atgataatca
     5581 tgtatttttc agtggttatt tggctatgaa tgctggcata gatttaagcg atacatcttc
     5641 agctaacgag gctgtagagc gtattaaagc tgtaatgaac cataaaaaag cagatgaacc
     5701 aatttatgct catggctggg atgctgccct gtggaaaact gacccatcag aagagctatt
     5761 gaatgaaata aaccactttg gtccaatcac agcgatcgac aaaaatcgca gccattgttg
     5821 gatgaatgct attgctaagc agacttatgg ttttacagaa aaagaaacca gtgctgaaag
     5881 tcgagtatta ttaattaagg aaatgctagc aaacaaaaag cttttagcag aggtttacgc
     5941 tgaatttgaa gcattactgc tttcaaaagg tgttatatca atgaaagaaa tcgtttttga
     6001 tgacgcagaa tttctttcta atatacctca gaggaaaata cttagtaacc tatatgtgca
     6061 ggcagtccaa gaacctctac agcatgaact tctatatgag tataaggaaa aagttttccc
     6121 tgaaaaggtc cgctttggtg gagtgaagat catggtagat ggtgttgttg cggatagaag
     6181 tggagatatt tacggtgttt atcagtcagg agtagcttca cccgagattg actatgaggc
     6241 aattaaagca gaagttgctg cattcaatga agtagagatt ccttgctgtt tgacaacgga
     6301 aggagataaa gcgggttata aagctgcgtc aattcttgtc gaatttggaa agcggttacc
     6361 tgaaggcgtt tttaattcga ttagtgattt ggaaatggtt actcaaaaga cagcagaaaa
     6421 aatgaacgaa ggacaagtag tagcagaggt atatccacaa attctcggct tgaatcaaac
     6481 gttagaagag gcttacatgt caactgttat aaaaaatgag tcaagtccac aatcttgtgt
     6541 aaaagttcaa cctcatcaaa agcacaatgt tttgcgttgt gaacctaact gccatgcctt
     6601 tctttctgag gagagaggtc aggagcagta gcgcagcgac tcttgatgtc tctcctcaga
     6661 aagaagagac tcgcacaggt tcatggtgct aaatgttatt cgaattaaat tctaaatatt
     6721 ttcgtggaga agccagccac tcagtgtctt tttccatcaa aagtgttcca attatccgag
     6781 tgatggaatt gatatttgga aaaatccgaa tcactcgttc tctccggcga atctcttcgt
     6841 tcaaccgttc caacacattg gttgtacgaa tccttcggcg gatattttca ggaaaagaca
     6901 aaatttgaat agcatcttca aagccgtttt ctaaaatgtc gcaagcagca cttaattttg
     6961 aatcacaacc atatttttcc aagaagtgct cttttctttc acgtgtcaat tcaagttcag
     7021 aggctttaaa gatactcttc aactcgtctt ttacatcaga agaaactttc tttggcagct
     7081 tatcaaaaat atttctcaaa aagtgggctt ggcatctttg ccagctcgca cctaaaaagt
     7141 tcttgcgaac agccttaact aaccctttgt gtgcatcaga aatgaccagt tttacaccga
     7201 acaaacctcg ttgaacgaac gattgaaaaa cggtatccca attatcttcc gattcgccgt
     7261 cttgaacatc aaaaccaaga atcgtacgtc gtccatcaga atcaatgccg ataccaatat
     7321 atacaccttt tgagacaata cgatgatttt cccttacttt catatacagg gcatcacaca
     7381 tgaaaaatgg atattccgag ccttctaggc tccggtttct ccactcaaaa acaaatggat
     7441 ccaactgttt catcagattt gaaacgaatg atttagaaac agtcgcacca tccgttagca
     7501 gttcaactgt tttagttact ttgcgagtgg agacaccaga aatgaccatt tcaatcatgg
     7561 cagcgatcaa agctttttcg cttcgctgat atctttcaaa gatagtagga ctaaacttac
     7621 cgtctctggt tcgtggaaca tgaagttcta acgtaccaat tcgagttgta aacgaacgat
     7681 cgtagtaacc atttctttgt gattgccgtt cttctgaacg ttcataggca tttgcctgaa
     7741 tatattgatt tcgttgttct tccatcagct gattaaacat gatagtcata agtgtttttg
     7801 cggtatcatt cgcaccgctt tcgtttataa ttgcttgaat ttcttcgctt tcaaaagtaa
     7861 aatgtacttg agtcattgat atcagtccta ttcgagtatg ttttctgcaa aaaacattgt
     7921 actcctaact gagatcaatg gcttttttga tgcttcactt ttacacaatt atatggacgt
     7981 aatcaaaaaa tgtttccaca gaggacttct ttaattattg tcgattagag gaaagtggtg
     8041 taacagtcac tagcggtaca gatttaccgc tgtttattac tgatattcct gaatcgatta
     8101 taagagcagt attccgtcgt tttcctgaag gagaagaagt ctgggagaaa gaaacaagct
     8161 tcacgacaac cgagctgctg aaaagtttta caagcaacag cttcaaagta aatggtttat
     8221 cggagtacgg agaaataaaa gtagggaaaa gcgccagctt agctgttttc agcgaggacc
     8281 tctgtactga tgactggcaa aaagtgatgg ctgcggaagt tatcgctacc tatcttgatg
     8341 gtgacttagt ttacaagaaa taatgctttt cgatataacg ttataaaacg aattaaagag
     8401 aggttaaaaa atggaaacaa tgaaaagaaa attcaccttc ccacatagtt atacattgat
     8461 ttttatctta attattttgg ctgcaatttt aacttggata attcctagtg gtcagtttga
     8521 gacagttgtt gaaaacgtcg caggtatgga aaaaacaacg gttgttccgg gaacctatca
     8581 ccaaatcgat aaggcagatt atggacaagg tttttcctct atactaatgg caccagctga
     8641 agggattatt tcagctgttg aggttgttgc ttttgttctc atcgttggtg gtgccttcgg
     8701 gattatccta aaaacgggag ccatcgatcg agggctgttt accttagcaa aagttctggg
     8761 agacaagggg atcttagtta ttccgatgtc gatgattcta ttcagcttag gaggatcaac
     8821 ctttggcatg agcgaggaag tcattccctt atttgcggtg tttatttctc tgatgttttc
     8881 tcttggctat gattccatga ctgcgatctt gattctattt ttaagtacac aagcgggata
     8941 tgttgggtcg acgattaatc ccttcaacgt tttaatcgca cagggagtag ctggcgttta
     9001 cggaaatccc ctgctttggt ttcggatgct atcctggatt gtcattactg ggatttcaat
     9061 tgttttcacc atgctttatg ctagcagagt caaaaagaat ccactgtcct ctattgttta
     9121 tgagagtgat ttaaaggtta agcataagtt tcaaaatttt gacactgaaa aagagttttc
     9181 aacacaagat aaactaatta tcgccggttt tatcgtaggt ttaggaatca tgatttgggg
     9241 tatcatttcc aagggatggt atatggttga aatttctgca ctattcttag gattaggtct
     9301 ttttgctggg ggcatcgcta gattttctca aaaggaaatt gctgaagctt ttgtcgaagg
     9361 ctgttcagat ttcgcctatg ctgctgtaat cattgggcta gctagaggag tcttggtaat
     9421 cttggaaggt ggaatgatta ttgacactat tctaaacagc ttggctaacc ttttaggtgg
     9481 tcttccaaaa ttcctgttca ctacgattct actcatttct caagtaattg tttccttttt
     9541 tgttccatcc tcctcaggag ctgcggcatt aacgatgccg gttatggcac cattgggtga
     9601 tctaatgaat gtaagtcgtg atgttgttgt tctaagtaac cagtttggaa atggtttaat
     9661 gaatattatc tccccaacta gtggtgtatt actggcagga ttagccatcg cagagattaa
     9721 tttctctaaa tggtttaagg ttggcttcaa aatatttgcc atcttaaccc ttgtttctgc
     9781 tgttttgtta tacattgcta cactctttta gtcttaatca tccattaata ggaggcaata
     9841 gttatgatta aaataaatca attagcagga atgaatatcc actatttatt ttattctctc
     9901 aaagaatttt tcgcttatca acagaaaatt ggtatttctt ctgttgaact ttggggaggt
     9961 gctccgcatt ttttcataga tgcttttact ggttctgttg caaagtttta aatctactat
    10021 caaataaggt agaataatag aaaaagatag caggaggaat gacgatgaat cattttaaag
    10081 gaaagcaatt tcagcaggat gtgattattg tagccgtggg ctactatctt cgttataacc
    10141 ttagctatcg tgaagttcga gaaatcttat atgatcgtgg cattaacgtt tctcatacga
    10201 cgatttatcg ttgggtg
//
LOCUS       DAMEEU010000091         9875 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.093, whole genome shotgun sequence.
ACCESSION   DAMEEU010000091 DAMEEU010000000
VERSION     DAMEEU010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9875)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9875)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9875
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.093"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(23..268)
                     /locus_tag="PB779_002466"
     CDS             complement(23..268)
                     /locus_tag="PB779_002466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HDE0739963.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(383..961)
                     /locus_tag="PB779_002467"
     CDS             complement(383..961)
                     /locus_tag="PB779_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDE0739964.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(1038..1568)
                     /locus_tag="PB779_002468"
     CDS             complement(1038..1568)
                     /locus_tag="PB779_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HDE0739965.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(1572..2432)
                     /gene="rlmB"
                     /locus_tag="PB779_002469"
     CDS             complement(1572..2432)
                     /gene="rlmB"
                     /locus_tag="PB779_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HDE0739966.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(2425..2820)
                     /locus_tag="PB779_002470"
     CDS             complement(2425..2820)
                     /locus_tag="PB779_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HDE0739967.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(2817..4229)
                     /locus_tag="PB779_002471"
     CDS             complement(2817..4229)
                     /locus_tag="PB779_002471"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HDE0739968.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(4226..4762)
                     /gene="cysE"
                     /locus_tag="PB779_002472"
     CDS             complement(4226..4762)
                     /gene="cysE"
                     /locus_tag="PB779_002472"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HDE0739969.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(4848..5087)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(5084..6544)
                     /locus_tag="PB779_002473"
     CDS             complement(5084..6544)
                     /locus_tag="PB779_002473"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HDE0739970.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(6714..7871)
                     /locus_tag="PB779_002474"
     CDS             complement(6714..7871)
                     /locus_tag="PB779_002474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HDE0739971.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(7905..9275)
                     /gene="radA"
                     /locus_tag="PB779_002475"
     CDS             complement(7905..9275)
                     /gene="radA"
                     /locus_tag="PB779_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HDE0739972.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(9338..9865)
                     /locus_tag="PB779_002476"
     CDS             complement(9338..9865)
                     /locus_tag="PB779_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HDE0739973.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         2509 a         2214 c         1785 g         3367 t
ORIGIN      
        1 gaatctcagg ctcgtttgct ttttaaactg cttcagttaa aaattcgatc tcaactgtcc
       61 gagtaagtac atctgaatag ctgtaagata ctcgttcaaa agaattttct tcaggatcca
      121 aatcaacaac gaatactgaa ggataggttt ctgttaaaac gccgcggcgt tctgtttgac
      181 gctttcttcc tgtctgagca accaacatga ttgggctgcc gatacgacct tctaaatctt
      241 tcttgattga agctaaagtt gttggcatac agttcacctc tactatcaac tataccacat
      301 atttttaaaa ttttcaagtt taccataaaa aaaaaagaaa tgcaataaaa ataaataaga
      361 agctcattaa gatttttcta aattattcct cattataaaa tttcaagtgt ttttttattt
      421 tgagttttac tctcccgtaa gcgctcatta cttgcttgtg atccattgct aaacattcag
      481 ccatgtctac aaaatcaacg ccttgcatat aataatgaaa aattttagct tctatttttg
      541 aaaactggat ttcgcaattt tcgattgctt cttttaataa aagatgctga atcgctaaag
      601 gttcttgcaa tgtgatctct gctaaaaagt ctggtccttc tgtctctatt ttttggtcga
      661 ttgagacttc atctttttga tcacgacgct tcagcgcgtt ctgcttcctc aacagagaat
      721 agatttgatt gcttataatg cttttataat aacttccaaa gctaacacct ttgctttttt
      781 cgtaagttct caatgcctga tataaagcga tccttgcttc ttgttcccaa tcctcagaaa
      841 cataatttct taaataatag gtgtttttca aacgtagtaa aagtggaaaa tatttttgat
      901 acagggcagc aaatgcttct tcgtcaccat tacgtgcagc gcgcaataac tcctcagaca
      961 taaaataatt cctccataaa ttcgtttatg gaggaatctt atcatcaatg attcatcgaa
     1021 ctgattagaa cgatatgtta tttatttttt ctcattaaat cgtccaattt ttgggacaat
     1081 ttttttaact gctcttcatt ccatggagaa ttacgtcgga aatcaataaa atgcatatct
     1141 ttattttctt gggctattgt tttttccgtt ttttttatcg tcttatataa ttcataagca
     1201 gaagttcgta atgctccttg ggaaaagatc atccactgtt ctgctaaatc gcttgtcgcc
     1261 actgtcactt gtgtcaaacg gtcattcagc tgaccagcga ttctctcgat ataactgtca
     1321 gccgtttcgt cttctttcgt aaaaacaaca tccaactggt atttcttata attttgttgg
     1381 atgcccggaa ctagttgggc atcgaagaca acgatgactt ccattccttc atatttcgca
     1441 taatttgata aacgatgtaa aagagcttct cttgcatccg ccattttgtc ctgcttttta
     1501 agctggacaa gttccggcca cgaaccaatc atgttgtagc cgtctacaat caacagctgt
     1561 tttttcatgg tctactcccc ctgacgttgg gaaaaagcct gatacataag caaaccagca
     1621 gcaacactgg catttaagct ctggacgtgc ccggtcatcg ggatcgtcag caattcatcc
     1681 atttcttttt tcaatcctgg actcattcct ttgccttcat taccaatgac taaagcaatt
     1741 gatcctttgg cattccattt ttggaagttt gtgccggtca tatctgtgcc aaatacccaa
     1801 aatcctgttt ctttgagctg ttgcacagct tgtaccaaat tcgtcacgcg tgcaacaggg
     1861 acatgttcga ctgccccagt ggaagtcttt gttacgatag gtgtgattcc aactgctcgg
     1921 tgttttggta tgatcacacc atcgacgcca cttgcgtctg ctgtccgtaa aatcgaccca
     1981 aaattgtgtg gatcttcgat gctatccaaa atcaaaaaga aggggtcttc ttttttctct
     2041 tttgttcgtt caatcagttg gtcaagggat aaatattcat aaggtgtaat cgcaagaacg
     2101 actccttgat gcacgccgtg atcgctcaaa gtttctaatt tttgtttagg aacccatttg
     2161 actggcacag cttgttcacg tgcgatttct ttcagttctt ctactttttc tcctcgtgaa
     2221 tcttcttgaa gaaagagttt attccctcgc ccttgttgta gcgcttctac tgcggcatgg
     2281 tgcccaaaga cgaaattatc ttctaatgct tcttcatttt gatcagaaac tgactgattt
     2341 cgtccagttt gctttttatt tgaatatcta ttttgttttt tgtcttcaaa tccacgtttc
     2401 gattgatgtt tgtttgttct ttctttaccc atttttttca ccaactttct gaatacacca
     2461 gcggatcaat tcttccatcc gctcggtttg ttttgtcaaa tgcagatagc ccatgagcgc
     2521 ttcgaaccct gttgcgaccc gatacgtcgt aacatcagca ttttttgcgc tcgtatggct
     2581 tttagcattt cttcctctgc gataataaag ttcttcttct tctgtcaaaa gatgttcttc
     2641 cagcatttgc tgaatcaaaa aggcttgtgc attcgcagaa acataattcg ttgccgcacg
     2701 atgcagctta ttgggttttg tttctccttg atcaatcagg tggtcacgaa catagatttc
     2761 gtaaatcgca tctccaacat aagccaaggc taaaccgttc aattgtgtgt aatctctcat
     2821 gcttctcttc tccatcgggt tccttgcggt gtatcttcta ataagatccc tttttctttc
     2881 aacaaatcac gaatttcgtc gcttcggaca aaatcacgat tgcttcttgc ttgatttcgt
     2941 tcttcgatca attgttcaat ctcttcatct aataactctt ctgctgtaaa taaaataccg
     3001 aagatcgaaa gccattgcga gaataaagct tctccttgtg ccaagacagc ggcagaaact
     3061 ttcggctggt ctagataagt gttcagccac ttagcaagct catagaccac tgtgatccca
     3121 tttgctgcat taaaatcatc gtccatttct tcgatgaatc gctgttctaa attttctaac
     3181 aaagcgattt tatccgcatc atctgccaaa ttctctgagg cagtttcttg gcggaatttc
     3241 aaattgtcaa acgtattctt cagtcgttgt aaattggtgg ctgcttcttt catcgtcgtt
     3301 tcactgtagc ggatcggacg acggtattgt gtggtcgcca tgaagaaacg caagacttgt
     3361 ggatcaacgt ttttgatcat ttcatgtaca gtgatgaaat tccctagaga tttactcatt
     3421 ttttcatcgt cttcgccaat cgttacatag ccattgtgca tccagtaatt agcgaatttt
     3481 ttccctgttt tcgcttcact ttgtgcgatt tcattttcat gatgaggaaa ttctaaatct
     3541 tgcccgccac catggatatc gatcgtttct cctaaatgtt ttgttgccat aacggaacat
     3601 tcaatatgcc aaccgggacg tcctttgccc catggtgaat cccaagaaat ctcgccaggt
     3661 tttgcttgtt tccataaagc gaaatctaat gggtcttctt tttgctgctg ttcttcccct
     3721 gtacgctgac ttgctccgac ttccagttca tcgatggatt ggtcacttaa tttcccataa
     3781 ttttcaaatt tacgggtacg gtaatacaca tcacctgaag attcataagc atagcctttt
     3841 tcaaccaaca cttgaataaa tgctaaaata tctggcatat gatccatgac tcttggatgc
     3901 agtgtagcag gctcgacatt caacgctttc gtatcttctt caaatgctcg gatgaaacga
     3961 tcagcaactt ctggtgctgt aatacctaat tcgtttgctg tacggatgat tttatcgtct
     4021 acatccgtga aattcgatac gaaatcgact ttatagcctc gatattcaaa atagcgtcga
     4081 attgtatcga aagcaatggt gctacgagca tttccgatat ggatataatt atacacagtc
     4141 ggtccgcaga catacatacc gacatgtccc ttttgtatag ggatgaattc ttcttttttt
     4201 ctggtcaatg tattgtagat ttttatcatt ctgatctcct cactttttct cctttgattc
     4261 gaacgacttt tgctggtact cctaccgctg tagcgtcgtc tggaacatct ttcaacacaa
     4321 cggcacctgc accgattttg gcgttttttc cgatcgttac cggtcctaat atctgcgcat
     4381 tcgcagagag catggctcct tgtttaacag ttgggtgtct tttacccgtt tcttttcctg
     4441 tgccgcctaa tgttacgcca tggaataaaa tcacatcgtc ctcgatttct gcggtttcgc
     4501 caatgacgat tcccattcca tggtcgatga acacgccagt tccaatcgtt gctcctggat
     4561 ggatctcaac accagttagg aaacgccaga attgagcatt gatcttcgcc aataaaaaga
     4621 gccggtgctg atataaaaaa tgagagaaac gatgccaaaa caaggcatga aaaccagggt
     4681 atgtcaaaac gatctcagct gtcgaacgtg cagccggatc gtttctcttt gctgcatcaa
     4741 tcgctcgggt aaaccaactc atgactttcc actcctttcg taagaatttt atgtaggaaa
     4801 tcatcttctt ataaagaaaa gaagcgcctt ttaaataagt ttccttatca aaagacgctt
     4861 tccgcgtggt tccacttttc ttcataatca atgattatct ctgacagcta acgcctgtta
     4921 tacgttcttg gctactttgt ttcctataaa acagtttttc ctgttttctg tgtttcgcca
     4981 agaccactcc cagaggcatt tcggcaacca ttcattgata ccttgcacca cccggtatct
     5041 ctcttgtaat gatcagctgc ttactttttt ctgttcatcg tgtttagttc agtacttgat
     5101 ttaaatgtgc taatgatttt tcacgaccaa gcaattcgat cgtttcaggc aattctggac
     5161 catgcatttg tcctgataca gctacacgga ttggcatgaa aagatttttt ccttttacgc
     5221 cagtttcttt ttgaacagct ttgatggcag ctttgacagt tggagcatct actacttcca
     5281 tttgttctag ctgtgctttg aatgcgtgga gaacagtagg aactgtttca ccagcaagta
     5341 cttcttttgc tgcttcattc aatacaggat gttcattgaa aaatagcgta gacagatcaa
     5401 cgatttctgc agcatagctc atttgaggtt gatacaggct aacgatcttc ttcacccatt
     5461 cgattgtctt ttcatctggg ttttctgcta cacgtccatc agcgattaga taaggcagac
     5521 acatgtcagt aaatgcatct agatccattg ctttgatgta atggttgttt acccattgca
     5581 gttttttcgc atcgaaagct gcgggtgatt tacttaggcg ttttggatcg aacattttga
     5641 tcaattcttg gtgttcgaag atttcgtctt cgcccacagg tgaccagccc aataatgcaa
     5701 taaagttgaa cattgcatct ggtagatagc ctaattcgcg atattgttcg ataaattgca
     5761 agattgattc gtcacgtttg cttagttttt tacctgtttc actgttgatg atcaatgtca
     5821 tatgtccgaa ggttggtggt gtccagccaa atgcttcata gatcatcagt tgttttggtg
     5881 tattggcaat atggtcatct ccacgtaaaa cgtgagtgat tttcatcaaa tgatcatcga
     5941 ccgcaacagc aaaattataa gttggcatac catcgcgttt ttgtatgaca aagtcgccac
     6001 cgatattatc ggattcgaac gaaatagcgc ctttcaccat atctgtaaat gcgtattctg
     6061 tattgcgagg cacacggaaa cgtacaacag attctagacc ttgtgcttct ttttctgctt
     6121 gttcttcagg tgtcaagttc gcacatgttc ctgcgtaatg aggcatttct cctcttgcgc
     6181 gttgtgcttc ccgttctgct tctaattctt cttctgtgca atagcatttg tatgctcgat
     6241 tgctagcaag cagctgatca atcagcggtt gatagatttc tttacgttca gattgacggt
     6301 aagggccgta ttctccagga ttttcaggag attcatccca attcattccc aaccaagcaa
     6361 ggttttccaa ctggcttttt tcgccatctt cgatattacg tttttggtca gtatcctcaa
     6421 tacgaataat aaagtctcca tcattgtggc gggcaaacaa ataattgaat aatgcagttc
     6481 ttgcatttcc aatatgcagg tgcccagttg gacttggtgc atagcgtacg cgtactttcg
     6541 tcattttctt cctcttcttt caaactagac tttgactaac agcaaaaatt ccgtcagtta
     6601 cggcttctca aatatcattt atttaaagcc actcagcaca aattttacct tttctaaggt
     6661 aaatagtaaa gccaactggt tgaatttcct taccagttgg ctgaatttct tttttatttt
     6721 gattgtttag tctttttctc tgtctctttt ttattgtcga ttcctcgtcc tgcatgtgca
     6781 ggtttagcaa agatcatgcg tccagcagct gtttgaaggg cacttgttac aacgacttcg
     6841 atacgttcat tcatgtaatg ctgtccatct tctacgacaa ccatcgtgcc gtcatcaagg
     6901 taggctactc cttgttggcg ttctgtcccg gcttttacta ctagaacatt catcgtttca
     6961 ccagggatga cgactggttt tacggcattt gccaacgcat tgatattaag aacaggtaca
     7021 ttttggaatt cagagacttt attcaagtta tagtcattgg ttacaatgac accatctaaa
     7081 agcttagcca atttgatcaa tttgctgtct acttcactga tatcttcaaa gtctccatcg
     7141 tacatttcga cagatatacc ctcttctttt tgcaaggcat ttaggatatc taatccgcga
     7201 cgaccacgca cacgtttcaa actatcccct gagtccgcga tgtattgtag ttcgtaaaga
     7261 acaaaattag ggatcatcaa ggttccttct aagaatccag tctttgtaat atcataaatc
     7321 cgaccgtcaa tgatcacgct tgtatccaag attttatatt tatggaaatt ttctcctgat
     7381 tttcgttcta acagttgact ctcaacttga ctagctgttt cttgctcgat ttttttgctt
     7441 cgtgaaccaa aaactttctt ccattcttcg attcgtgtcg ttcccattct caatcccaga
     7501 tagcctaaga tgatcatcag taaaatcggc aatacactat tgacgaatgg aatttccata
     7561 ttgtaaagag gggtcgagat cacaacacct aaagtcaatc cgatgatcgc accgatcgca
     7621 ccgaagagaa gataagtcaa gctgacctca cttagttttt gttctacttg tttgataata
     7681 gctgagatat gtttggccaa cagcaaagat aataaaaaga aaataagtgc gcctaacagg
     7741 ctgttggtaa atgtattatt cagccatccg tttgactgtt gaccgattgc ctgccaagct
     7801 gagggtaaaa atgaaatacc caagcttgcg ccgacaatga tcatcagcaa agtaatgaca
     7861 cgtttttgca tcgtttttcc tccgtttcga caatcattta ttagttagcg gaacacacgc
     7921 ttcaacgttt cagccaaagt tgctactcca actatctcga ttccttttgg cgcttcccag
     7981 ttacctaagt tgtttttagg taggtatact tttgtgaagc cgagtttttg gacttctttg
     8041 actcgttgtt caatatgact gacacgtctg atttctccag tcagtccaat ttcaccgatg
     8101 aaacattccg ttggctgtgt tcctttttct ttatagcttg aagcaatact gacagcgata
     8161 gctaaatcaa tcgctggttc atttaatttt accccacctg cagcttttaa gtaagcatct
     8221 tgattctgaa gaagcaaccc agctcttttt tccagcactg ccatgatcag agatacccga
     8281 ttgaaatcaa gacctgttgt tgttcgtttg gcatttccga acatagtagg tgtgactaat
     8341 gcttggatct ctaccaaaat tggacgtgtc ccttccattg ccacaacgat agcagagcca
     8401 gttgcaccgt ctaggcgttc ttctaagaaa atctgtgaag gattagcgac ttcttccaat
     8461 ccatgctcat gcatttcaaa aatcccaatc tcattcgttg agccaaatcg gttttttact
     8521 gctcgcaaaa tccgaaaact atgatgttgt tcaccttcaa aatataacac cgtatccacc
     8581 atatgttcta acattcttgg gccggcgatc gagccttctt tggtaacatg accgacgata
     8641 aaaatggcta tcccatttgt tttagcgatt ttgagtagtt ctgcagtggt ttctcttact
     8701 tggctgacac ttcctgccac acttgtgatg tctggctgcg tcatcgtttg gatggaatca
     8761 atgataacat aatcagggga gatatgttcg atggcacgac tgatttcgtt catatctgtt
     8821 tcagcgtata gataaaattc tgtgttgata cttccgaggc gttccgcgcg taattttatc
     8881 tgctctgcgc tttcttcgcc ggatacatat aagacttttc cgcctatggc tgctaattgc
     8941 tgagaaactt gtaacagcaa agtggatttc ccgatacctg gatcgccacc aatcaagacc
     9001 atagaccctg gcaccacacc tccgcctaac acacggttca gttcttctaa ttttgttttg
     9061 atccgaggtt cttttttagg gacgacgtct gcgatttttg ttggttttgc tttttctcct
     9121 gtcaaacttg tccgagttct gcggtccgtt gtatcttgtt cgatttcttc gaccatcgta
     9181 ttccattttc cgcaatttgg gcagcgtccc aagaacttag gcgacacata cccgcaattt
     9241 tggcaaacaa attgtacttt tgattttttt gccattgtac cgcctccttt tatcctaatc
     9301 atgagacatt aaatcaagct taagtatctt taacgtttta tttactggaa gaaccaaatc
     9361 cgccttgacg ttgagcagtc gtttgatctt gatctgcttt taaaaacggc aaaaagatcc
     9421 cttggccgat acgctcgcct tttttgatca ctacatcctt gaaaccaaag ttggtgaatt
     9481 ggaacatgat atggccttca tttgcctcat tattgtaata atcactgtca atcacaccta
     9541 ctccgtttgt caacactaaa aaccgcttca acggattgct tgaacggtta gcaagctgca
     9601 aaaattcatc ttctcccatg taagctttga ttccagtagg cacgagggtt ggtttcaatt
     9661 gtttttcatt ttctgataca tcttttttca atccatctgc gactgtttcc aacccctttt
     9721 tccagcctgc tttccagata cttggaatca cgacctcttc tgctgcttca aaatcatagc
     9781 cagcagcatg atgtgtagcg cgctgcggta gattgatatt ttgatcttta tatttagaaa
     9841 taacttcaaa tcctcttttt ctcaccggtt ttcct
//
LOCUS       DAMEEU010000092         9873 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.094, whole genome shotgun sequence.
ACCESSION   DAMEEU010000092 DAMEEU010000000
VERSION     DAMEEU010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.094"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(96..2216)
                     /locus_tag="PB779_002477"
     CDS             complement(96..2216)
                     /locus_tag="PB779_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDE0739974.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            2446..3624
                     /locus_tag="PB779_002478"
     CDS             2446..3624
                     /locus_tag="PB779_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HDE0739975.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            3640..4398
                     /gene="aroD"
                     /locus_tag="PB779_002479"
     CDS             3640..4398
                     /gene="aroD"
                     /locus_tag="PB779_002479"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HDE0739976.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            4421..4906
                     /gene="ybaK"
                     /locus_tag="PB779_002480"
     CDS             4421..4906
                     /gene="ybaK"
                     /locus_tag="PB779_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HDE0739977.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(4977..6230)
                     /locus_tag="PB779_002481"
     CDS             complement(4977..6230)
                     /locus_tag="PB779_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDE0739978.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            6347..7696
                     /gene="gdhA"
                     /locus_tag="PB779_002482"
     CDS             6347..7696
                     /gene="gdhA"
                     /locus_tag="PB779_002482"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HDE0739979.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            7808..9154
                     /locus_tag="PB779_002483"
     CDS             7808..9154
                     /locus_tag="PB779_002483"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HDE0739980.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(9462..9848)
                     /locus_tag="PB779_002484"
     CDS             complement(9462..9848)
                     /locus_tag="PB779_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDE0739981.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3148 a         1793 c         2023 g         2909 t
ORIGIN      
        1 ttctattacc gtagatgcaa gcttttgaac actgtttatt cgaaaagagg agcagcgaca
       61 ataattttgt cgctgctcct tttaaattta ttttatcatt cggaagaact tgtggtcgtt
      121 ccgtgaagtt cttggtacgt ttgcgtttta taaagatcaa cagttgattg tccgttgtgt
      181 tcactaaaga cactagttga cttgtcacca agagattttt cagcttcttt taatttctct
      241 aagccattct tgtagtcata atcactggta tcaattgggt ctaatccact attcgtatag
      301 aaccgaagaa gatcaccatt attgatttgg tcagaaacag ctaactgttt atcaactttt
      361 tctttcagtg aatcaatttc attctgtact tcctcagtag gttcagtaat agcttcacca
      421 gtttcgttac tatagatcgt accaccgtag taagtatatt ttggtgtaac aaaatcacca
      481 tcacggaaag aaacaagctg ttcatgatct ttcgagaata gatcttgtcc taactgaata
      541 taattttttg tatctacacc tagtaagtga agtaatgtag gcaaggcatc aacttgtccg
      601 ccgtaagtgt gattgattcc gccctgtgtt tgtccaggga tatggatcat ataagggaca
      661 cgctgcattt gtgcattgtc gtagtttgtc caagtagaac ttgtttttcc aactaattca
      721 gctagatttt tatttcttga attcgagaca ccgtaatggt caccgtaaag gacgatgact
      781 gaattatcat acaagccgct ttctttcaaa taattgaaga attcttgtac ggcggtatct
      841 aaataattgg ctgtcgcaaa gtaaccgttg atcgtttcat catttgtatt ggctaacggg
      901 aatcctgctt cgtcattggt gaattttgaa taaggataat ggttagatac agcaatgaat
      961 tttgaataaa atggttgttg cagacgttcc aagtattgta cggattgttg gaaaaatggt
     1021 ttatcatgca acccgtattg gaacgaattg tcatcattaa catcataata agaagaatca
     1081 aagaaataat catatcctaa attcttgtat gtctcgtttc gattccagaa tgtaccagcg
     1141 ttcccatgga ataccgcact aatgtaacct tgtgtttgac ttaaaatatc aggtgcagct
     1201 tggaaagtat tttttccgcc taattgtgtg aacaaggagc cttgattcaa gccaaacaat
     1261 gaattttcca tcagcgtttc cgcatcgctt gtttttcctg cttttacttg atggaaaaag
     1321 ttgtcaaaac tgaacgtgct gttgctgtgg taaagactat tgatgaaagg tgtaacttca
     1381 tgctggagac cattctcatc tgtcaattta taatcgatca ggaattgctg gaagctttct
     1441 aaatggatat aaatcacatt ttttcctcta gcgagcccga acaaatcgtc atttggtgct
     1501 gcataatgtt cttttacata attttctact tctttcatat cattgggact tgcttctgcc
     1561 cgcacttggt ttgtctggta agtttgaaca ccgtcataaa ccatgaaagc attcaagcca
     1621 agatatttga ccaaataatc acgagagaat gttcgagtca gcaattctgg acgatcagct
     1681 tccgccataa aaagatttcc tgagaaaatc ataactgcta atgtagagat cgcaaaagcc
     1741 attcttgctc ggatcgggcg agggtccaac ttgatttttt ttgcaatcag cagaacagtc
     1801 aagataataa aatcgatcca atagatcaca tcatatgggc gaaacagtcg aatggcactt
     1861 tctcccagac cactcgctac tttcccagca cctaaaatcg tgttgatcgt aatgaagtcc
     1921 gtgaattctc gataataagt gacattcgaa aaaacaagca atgtcaaaag aaaataaatg
     1981 accatcatcg tgatataagc aactctaggg cgtctgatat aaagagcaat tccaagtaat
     2041 aacaatgtag ttgcaatagg gttgataaac aagataaagt attgaatgcc actttcgatt
     2101 ccgagatgga aatcaactaa ataggcaaaa atcgttttca accaaagtaa aacgactagt
     2161 aaagaaaaaa atccgagcct cttattcaaa aaggcaggtg tttttataca tttcaagata
     2221 atcttccttt ctgcacttct taatcacaga agtgtcctga aaccatgtta cacagctcac
     2281 ttattctcat ttattttact agtatgacaa tatagtgtca attgaaacca gaagtttatg
     2341 ctgtttcatt aaggttttct ttaagcttca tgaaaaaatg agcagtaaga caagtcctat
     2401 gttttttgtt atacttggga agagaaagct aaagcaggtg aaggaatgaa agtaaaagta
     2461 aaaaaaagag caagcaatcg attgaaaaaa ggatatccac tgatccaaaa agaagacctt
     2521 gctcatcccc aaaaagaaac cacgcaatgg gtggaattag ttgattcgca aaaccaattt
     2581 atcgcaaaag gatatctagg aaagcagaat aagggaatcg gttgggtatt gagccagcag
     2641 aacatcccat ttgatcaatc tttttttgaa gaattttttg tgaagtcaaa agaaaaaaga
     2701 actttctttt tttcagatga ttctactacc gcttttcgta tattcaatgg agaaggagac
     2761 gggatcggcg gtctgattgt tgattattat gcaggttatg ctgttttttc ttggtataac
     2821 gaaacgttat atgcacatcg tgaattattg attcaagctt ttcgtgaaat ctacccggaa
     2881 atcataggag gctatgagaa aattcgattt gaatcagtaa atctgcctga gagccagttc
     2941 atttacggaa aagaggcacc ggaacccttg atcgtaaaag aaaacggagt aaaatttgcc
     3001 gtttatttaa atgaaggatt aatgactggg atctttttag accaaaaaga agtacgggga
     3061 tcattagcag aaggtttcgc ttctgggaaa acagttttga acatgtttag ttataccggc
     3121 gccttttctg ttgctgccgc aatgggaggg gcaatcgaaa caacaagtgt cgatctagca
     3181 aaacgcagtt taaaaaaaac acaggaacag tttgaagtga atggtttgga tgtcgatcag
     3241 caaaaaatca ttgttatgga cgtattcgag tatttcaaat acgccaaaag aaaacaattt
     3301 ttatatgaca tgattgtatt ggatccacca agttttgcca gaaataagaa aaaagtcttt
     3361 cgcgtagcaa aagattatgg ggaactggtc aaggatagtc tggatatttt agcagaagac
     3421 gggatactta ttgcgtctac aaatgctgcg aatgtctcga tagaacaatt ccaaacaatg
     3481 attgaagagg aattccatgc caaaaatgtt tcttttgaac aacttgcttt atatcgtctg
     3541 ccaaaagatt tccagacgac ggataccttt ttagaaggca attatctgaa agtgtttgtt
     3601 tatcaaatta aaaataacca ttagaaggag cgatgcagaa tggttcgggt aaagggattg
     3661 aatataggaa gcggtagacc aaagatttgt gcgcctctta tcggggccgt ccgagaggaa
     3721 gtattacgtg aagcagttct tgcacgtgaa gcaggggccg atttagtcga atggcgagtc
     3781 gatcattatc gtgaagtttt ttcttttgat gaagtagcag aaacattggt tcttatccat
     3841 gagatgcttg atggactgcc gttattattt acgtttcgta ccttagctga aggcggagaa
     3901 caagacatat cgatccgtca gtatcgcgac ctttatgaac atgtgataca cacaggatta
     3961 gtagatatgg tcgatatcga gttgttcaaa gtagaaagtc taggaaaaag actgatagag
     4021 gaaatcaagt ctttaaacat tcctttaatt atcagtagtc atgattttaa agaaacacca
     4081 gcagaccctg tcttgcttta ccgattgaat gttatggaac attttggagc cgatatcgga
     4141 aaactggcag taactcccaa taatgaacga gatgttttgc ggttgatgga gttgactaga
     4201 cgggcaaatg cttttgtctc catgcctatt attacgatgt ccatgggaaa tcttggtaaa
     4261 atttctcgtc tggttggcgg aacgacgggt tccgttatga catttggttc cttaagcagc
     4321 gattctactt ctgctccagg acaattaccg gtcaaagcat tgaagcaaat tattcaatta
     4381 ttaaatgaac cgttgtagaa caagtttgag gtgatatttt ttggcaaaga aaaaaatagt
     4441 aaaaacgaat gcaatccgta tggtcgaaca aaaaaagatt ccctatacag agcacgaata
     4501 tgagtgggac gaaagccacc taagtgcgtc atcggtcgct gaacagcttc cagaaagcca
     4561 atctcgtata tttaaaacac tggttgctgt gggcaatgtg acggggcctc ttgttgctgt
     4621 gataccggga gaagccgaat tgaatctaaa aaaattagca aaagtttcag ggaataaaaa
     4681 agtagaaatg ctccatttaa aagatttgga agcaacgacc ggatacatac gtggtggctg
     4741 ctcgcctata ggtatgaaaa aactatttcc tacttattta gatcaaattg cagaaagcta
     4801 tgaacaaatc attgtctcgg ctggcagaag agggctacag atggagttag cacctcaaga
     4861 tatctgtgca ttaacgagcg gacaatttgc agatataaaa caataaatca tacgtataaa
     4921 agaaagaagg aggccgggat gttgtttgtc cagtctcctt ctttcttttt tatacattat
     4981 gctctttgcc cggcattcat tcctgctaca tgccctgtag cgaaagccgc tgtgatatta
     5041 aagccgccag tataaccatt gacatccagt aattctcccg caaaatacag accatcaatg
     5101 attttactct ccaatgtttt aggataaatt tcctttagag aaacccctcc gccagttaca
     5161 aatgatttct caataggaaa agttttgttg attgatagct taaactcttt gcatagttga
     5221 acaaaatctt gaatttgttt ttgagaggct tgttgtcctg tcagatgatc catttcaagc
     5281 cgctcaagaa agaaaactaa caatcgctca ggcaatatac catgccaagc attgaccaag
     5341 ttctttttgg ttgctttact tttttctgtc aatatatgaa taagctcttg tttggtttgt
     5401 gtagggaaac aatccagaga aagtgtcact ggttctcccg ttttctctaa ttctttattg
     5461 acaaaacttg aacaacgcag tgcagccgga ccagaaatac cgaaatgggt gaaaagtaaa
     5521 tccatcgtat gttcagtcaa tacacgacct tttttattta aaacgcgtaa agtgatgtct
     5581 tgtaaagaaa gcccttgaag tgttttctcc tgaatatacg gttcatccga tatcaagggg
     5641 gactctgtcg cataaagagg cgtcaccgtg tgacccactc gcttcacgat cttgtaccca
     5701 tctccagtag aaccagtaga tggataagtc cgtccaccag ttgttaagat aatggcagga
     5761 gcatggaact cttcgaattc cgtgcgtata ccgtaaattt tatgttcttt gtggatcaat
     5821 ttctctactc gagtagagaa tagaagcgtc acatctagtt ctttcagacg attgagcaat
     5881 gcttcgataa tcgtttttga tttatttgtt acaggaaaca tccgtccatg atcctcttct
     5941 tttaaatgta cgccttgtga ttcaaagaag ttcatgatat cgaaattatt ccattgcgca
     6001 aacgtactat ataaaaactt tccatttcca ggaatatgtg caatcaaatc atcaacagga
     6061 cgattgttcg taacattgca ccgaccacca cctgtcatca gtagtttttt tcctgctttt
     6121 ttgttttttt cgatcaagag tacgcgtgcg ccttgttcag ctgcactgat cgctgccatc
     6181 atcccgcttg ttccagcgcc gactacgatc acatcataca gtttttccat tccctcacct
     6241 caaggaaagt gtagcatatc tgaagaaaga aaacagaaaa aaatgttttg agccaaaaga
     6301 gaaaatgagc taaaatgagg gaagataagc aaaggagcgt ggaacgatga caaacgcaac
     6361 agaatatgtt caagcaattc aagaaaagct acatcaaaag gatcaagggc aagaagaatt
     6421 tttacaagca atcgatgaat tcatgcccac ggttatgtct tttttggaca ctcatcccga
     6481 atatatcgaa aagaatatct tagaactttt aacggaacca gaaagagtta ttcaatttcg
     6541 agtgccttgg caagatgatg aaggaaactg gcgagtaaat agagggtacc gtatccaata
     6601 caactcagct atcggccctt ataaaggtgg attgcgcttc catcctagtg tcaatctaag
     6661 tatcttgaaa tttttggctt ttgaacagat tttcaagaat agtttaaccg gtctgccaat
     6721 cggtggagga aaaggcggaa gtgacttcga tcctaaagga aaatctgata atgagatcat
     6781 gcgtttttgt caaagtttca tgctggaatt gtcaaaacat atcggcccat cgattgatgt
     6841 tcctgcggga gatatcggtg taggagctag agaaatcggc tatttgttcg gcgaatataa
     6901 acgattgaaa aaatatgata ctggtgtgtt gacaggtaaa cctttggatt tttggggaag
     6961 taagatacgt acggaagcta ctggttatgg attagtgtat tatgtcaaac atctattgaa
     7021 cgaagaaaaa gattcattta atcaaaaaac agtttttgtt tccggaagcg ggaatgtagc
     7081 catttatgca atcgaaaaag tgcaagagct aggcgggaaa gttgttacat gttcagattc
     7141 tagcgggtac atctatgatc cagaaggaat agatgtgaaa ctattgaaag aagtcaaaga
     7201 aatcaataga caacgtttga cggaatacgc aaaccaacgt ccttctgcta tttatcatgc
     7261 tggagaatct gtttggacat tgaaagaaaa agcggatatc gctttgccat gtgctactca
     7321 aaatgaaata gacgaaagct tggccgaaat cttagtagaa aatgggatca aaatcgtagc
     7381 agaaggcgct aatatgccat gtacagtaaa agctgtttct gttcttcatg aagcaggcgt
     7441 gtggtattgt ccaggaaaag ctgctaatgc tggaggagta gcagtatctg ctttagaaat
     7501 gagtcagaac gtccagcgat tgacttggga aagagagcaa gtggatgagc agctggatca
     7561 aatcatggaa acgatttacc atacgtgtcg ccaaacagca gccgagtacg gcgacgaaaa
     7621 aaatctgctt cttggagcaa atgttgctgg atttgaaaaa gttgccaaag caatggcagc
     7681 agaaggttta gtttgaaaaa tgaaactttc ttggaaatat tgtcagcatt ttgtttattt
     7741 gcttgaaaaa taataaaaaa aaacgtaaag tattacctgt agagtaaacc tataaggagg
     7801 agaacaaatg gcacacattc attttgacta ttcaaaagta gcaccgtttg tcaacgaaca
     7861 agagttaggg tacatgcaaa gccaagtaac agcagcccac aacgaattac gggaaggtac
     7921 tggcgcagga agcgacttcc gcggctggat cgatttacca acgaactatg acaaagaaga
     7981 atttgcacgt atcaaagaag cagctaaaaa aatccaatct gattctgaag tattagttgt
     8041 tatcggtatc ggtggttctt atttaggcgc tcgtgcagcg atcgacttct tgaatcacac
     8101 attcttcaat ttattagata gcaacacaag aaaagcacca caaatcttct ttgccggaaa
     8161 ttcaatcagc tcaacatata ttgctgactt gatcgaagta atcggtgatc gcgacttttc
     8221 agtaaacgtt atttcaaaat ctggaacaac tactgaacca gcgattgcgt tccgtgtatt
     8281 caaagagctt cttgttaaga aatatggaca agaagaagca aacaaacgta tctacgctac
     8341 aacagataaa gcaaaaggtg cagttaaagt agaagcagat gcagaaggtt gggaaacttt
     8401 cgtgattcct gatgacatcg gcggacgttt ctctgtatta actgctgttg gtttgttacc
     8461 aatcgctgtt agtggtgcag atatcgatgc attgatgcaa ggtgccgctg atgcaagcaa
     8521 agcatactca agcgacaaac tagaagaaaa cgaagcttac caatacgcag caatgcgcaa
     8581 cattctttac cgtaaaggca aagtaactga gttgttgatc aactatgaac caggaatgca
     8641 atacttctca gaatggtgga aacaattgta tggtgaatct gaaggaaaag accaaaaagg
     8701 catctatcct tcaagcgcaa acttctcaac tgatttgcac tctttaggac aattcatcca
     8761 agaaggacgt cgcaatattt ttgaaacagt tgtgaaggtt gaaaaacctc gtaaatcaat
     8821 cacaattcct gaacaagcag aagatttaga cggtctaggc tacttgcaag gaaaagaagt
     8881 ggacttcgta aatacaaaag catttgaagg aacattgctt gctcatacag acggtgacgt
     8941 gcctaacttg ctagtcaaaa ttccagaaat ggatgcttat acattgggtt atacaatgta
     9001 cttctttgaa attgctgtag gtatttcagg ttacttgaat ggaatcaacc cattcgacca
     9061 accaggtgta gaagcttaca agaaaaacat gttcgcactt ctaggcaaac caggctttga
     9121 agatcttgct aaagaattga acgaacgcct gtaagataag ggtttttcgc tagatttaaa
     9181 taatcagtga tagaaacatg ttcgctttaa aatgaaaact ggtacccatt taggtactca
     9241 aacatactgc atcgtttatt cagaataagg ggctgtgaca agacgtttgt cacagtccct
     9301 tgtttgtata gaaatcgatt gattgccttg ctctttagtt tgttttagga ctttaagaac
     9361 agtgaggctg acttcgaagg ttaattctgt ttttttgttt tctagaatca gtaagcaaaa
     9421 aagcactcac ttcgagtgct tttttgcgat atattcttag cttaagatag gcctaatttt
     9481 tcttttacag atgagggtac cttatcgctg gtaattactt ttttctctat gatccgcttt
     9541 tcgcttgctt tcaactgcaa gatcgttcct tcggggtaag cagaaccatt ggcagagtca
     9601 ccagaagtaa tgacatcgaa atctaactgt cttttttcac cgttttcagc ataagcatct
     9661 acgttgtatt taaaacctct tccaattact tccccattat ctgctttgat atcagtttct
     9721 gcaggcattg gagctttgac taccgcataa taatctttac ctacataagt agactgatag
     9781 tagtcccaac ctttccatcc tataaaagca atcaatatga taacgatcaa ccctaaaatt
     9841 tttttcatga aagatctcct tttttatttt tat
//
LOCUS       DAMEEU010000093         9667 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.095, whole genome shotgun sequence.
ACCESSION   DAMEEU010000093 DAMEEU010000000
VERSION     DAMEEU010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9667)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9667)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9667
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.095"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..650)
                     /locus_tag="PB779_002485"
     CDS             complement(<1..650)
                     /locus_tag="PB779_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HDE0739982.1"
                     /translation="MKGDVIVEIKVLFENSRINLNFKSGHGLSLLINYSGKKYLFDAG
                     ANKKLVYNATKMGETLNDLEAVIISHGHSDHTGGLRYLKSGNAPIYTAEGVTLPHYLK
                     ILTTFLYVGIPKNEILKMHENLHTIKTKTELAPSFHIIPLGKANSTTKNLYKKMDDKF
                     VYDDFSDELLVVIEQEDGLIVFTGCSHHGIIDMMEIALETFPTKPIKYLIGGFHMIG"
     gene            975..1391
                     /locus_tag="PB779_002486"
     CDS             975..1391
                     /locus_tag="PB779_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HDE0739983.1"
                     /translation="MATIILASHGEFAQGLKQTATMIIGDSVPIHALSAFRDEDESIL
                     VQIKKLLATIDIEETYILTDILGGSVNNDMLTIIKEYEGLQLITGMNLPLVISIATYN
                     GKIGESELEKLIKESQQSVIDCRKLLVEQLTGGDDL"
     gene            1388..1858
                     /locus_tag="PB779_002487"
     CDS             1388..1858
                     /locus_tag="PB779_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HDE0739984.1"
                     /translation="MIKLVRIDHRLLHGQVVFSWSKSLNINRIIIANKEAANDEFKKM
                     SLNLSKPTGIKLTIFSVEQLLEKMPKIETLNENIMLIFGNTKEIRQFCEAYPKVQEIN
                     YGGIIKKEGSKQFSNAIFLNESEQEDAKKLKALGIKQFIQQVPTSKKEDLNTML"
     gene            1872..2645
                     /locus_tag="PB779_002488"
     CDS             1872..2645
                     /locus_tag="PB779_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0739985.1"
                     /translation="MLVQSIGLGLIGVFCILDSRLLGRMNFERPLIVSTLVGLVLGDM
                     EKGLIVGASLELMSLGLVNIGAAAPPDMNMASIIATAFAILSNANAEAALTIAIPISV
                     LGQILGILMRTILSNLTHVADRFIEQGKFSQARRIHILYGSGLYALMYFIPIFLAIYF
                     GTNLVSQIVDAIPEWLTNGLTVASKILPAYGFALLLQTMLTKKMVPFLLLGFLITAYS
                     GLGIIGIAAFACIVAFVMVQVQGKNSNGNQNEPDPLDDL"
     gene            2659..3471
                     /locus_tag="PB779_002489"
     CDS             2659..3471
                     /locus_tag="PB779_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HDE0739986.1"
                     /translation="MKEKDQNAWKYRQFLWRSWAIQASWNYERQMNMGFMYGIAPILD
                     NIYKNPEDEAMKKEAYERHMMYYNCTPQTSAFVLGLTASMEEQYYEDQENFNPESISA
                     VKTSLMGPLSGVGDSFFQGTIRVLAFGLGINLAQQGSILGPILAMLISFVPSFLVTYY
                     GGKIGYNMGNKYLSKLYQEGLMDKVMYVCSIVGLMVIGSMIASMIGITTPIQMGKAFV
                     LQDVLDSIMPQFLPLGLTFFMYWLLQKKVKTGWMLAICLVGGIIFSLLGILQ"
     gene            3525..4490
                     /locus_tag="PB779_002490"
     CDS             3525..4490
                     /locus_tag="PB779_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0739987.1"
                     /translation="MNSKEIVKEIVAKKEVKSIVFVGCGASKADLYPAKYFLDQNAKQ
                     LRISHYTASEFNYATPASVDESTVVISASLGGTTPETVEANAVAKEKGATVISLTRSI
                     DSPLTKDADYVIYHRFAENYAAKLEKTGYCLELAVELLHQVEGYDHYEAMQEGFATIY
                     DLAQKSAESARKDAKKFAERFKDEKVIYVMSSGATHEVAYSTSICLMMEMQWINSGTF
                     HSGEFFHGPFEIVDKDVPFILLMNDGKTRNIDARALTFLERFDTKTEVVDALDYGLSS
                     HIAKEVLDYFNPFVITAVFRVYAEELSEAREHPLTKRRYMWKLTY"
     gene            4606..7329
                     /locus_tag="PB779_002491"
     CDS             4606..7329
                     /locus_tag="PB779_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HDE0739988.1"
                     /translation="MQRLNDYLYQLTLLLKSTPSDNYSARSISQALQLNRSTISSYLN
                     EGVREGLFIKVKSYPVLFLHRTALEELHITLNNSEIESIESLLTISQKPALDQVIGSK
                     GSLKEAIDQIKTAVLYPGKGLPLLLIGASGSGKTFLANKIYEYAVEEKVIHTSAPFID
                     YNCAQYVSNPELLSSALFGYTKGAFTGASQEHTGLLEKADGGVLFLDEVHRLSEEGQE
                     KLFTFMDTGEFSPMGDNSIRKKADVRLVFATTENIYTTFLPTFLRRLPVIVNLPRFQQ
                     RPSFERLSLIDEFFVSESKILAKELSVSDALIHFLMNSDFEGNVGNIKNIIKYACGNA
                     YIHQKSQQTIQVKLLDMPLEYSYKFKEQLNKPRKKRADRIYYPEETRQVQLERNNQLF
                     VQFFDQLLTGFSEVIENNKDIKLFLEEMVTKVTQVMDTLIFQEDYEKEQSLYAILNYH
                     IRQSIDFMRESYGFEQDGNRVVALANYLYVKDNQVIFENSLQEKKTKDQLNEFFANVL
                     ETPYWYAKKILSLLSECLDQPVYEEDIFFITLYFYSLNVTNVKTGIKSIVLAHGYSTA
                     SSMANVANRMLNKNVFQAYDMPLDITLEKIEAKLIQFLGDYRTDSGLILLVDMGSLNQ
                     LGGLLVNHLNGPLLIIDHINTPLLLEVGQQVLNNKSITEIGAEIETSLTFKKQLLLPK
                     KKKKKAIITCCYTGIGSATQIQEILTKCLKDAVRELVIIPYDYKKLLENKNFETPFQL
                     YDVIMIVGTEDPKINQIPYIGLDRLINGEAIGEFVHYLEKELTIEVNDLQKELIFNFS
                     ISKIVENLTILDPDKVLSFVQKAIKELSKLLNFDFSNNQLFLLYLHCSCMIERIVRKE
                     SVDEQEDIEEYMQANGEIMDKIHSAFFEIEREYTIEIPDLELRLLSDIVQG"
     gene            7342..7974
                     /locus_tag="PB779_002492"
     CDS             7342..7974
                     /locus_tag="PB779_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HDE0739989.1"
                     /translation="MTMGVIFDMDGVLIDSETFYFERRMNFFQELEIDPGSNQIDDYV
                     GKTEAAIWETLVPEDKSLREELYPKYVDYRKTHPIDFAKDLRKEVKPLLDFLKKRDIP
                     LALASSSPVVEIESMLIQCELTEYFSFVISGESLKQSKPHPEIYLKAKQQLDCDFFIA
                     VEDSTIGIKSAKAANIYTVALKQPMQIDQSEADIQIESLQELEQIVLEKG"
     gene            8873..>9667
                     /locus_tag="PB779_002493"
     CDS             8873..>9667
                     /locus_tag="PB779_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0739990.1"
                     /translation="MKNLQLKFIVDPSIVRWFRIINQFERNQLATKGELAKSNHVSER
                     TIQTDVNKMKDYFSESVQFVSTKSGYSFQKERPVLFLKQKEQLLENEILFELLGNVFY
                     GELEDMTELIDRFHLSEATFRRYLKQIQPVLEEYGLELSLYPLDLKGEEANIRKFFKD
                     FYYEGEMTPHTLVPPRDLHELVQATFYDKFEYFSIGTGTSPAEFYYSLYIAIERVRQG
                     KTIAIPQGLIERVIASENFRLMYSLKEAIQTNYQVALSEEEFCWLYL"
BASE COUNT         3261 a         1477 c         1884 g         3045 t
ORIGIN      
        1 ccaatcatat ggaagccacc gattaggtat tttatgggtt tagtcggaaa tgtttcaaga
       61 gcaatttcca tcatatcgat aatgccatga tgactacagc cagtaaagac aatcagaccg
      121 tcttcttgct caattacgac caataattca tctgaaaaat catcataaac aaatttatca
      181 tccatctttt tgtataaatt cttggtggtc gagtttgctt tgcctagggg gatgatatgg
      241 aagctcggag caagttctgt tttcgttttt attgtatgta aattctcatg cattttaagg
      301 atttcatttt taggaatacc aacatacaga aacgtggtta aaatctttaa ataatggggt
      361 aaagttacac cttcagctgt ataaataggg gcgtttcctg attttaaata tcttaacccg
      421 ccggtgtggt cagaatgacc gtgtgaaata atcactgcct ccagatcatt caaagtttcc
      481 cccattttag tcgcattata gactaatttt ttattagcgc cagcatcgaa gagatatttc
      541 ttccctgagt agttaattaa gagagataac ccatgtccac ttttaaagtt caaatttatt
      601 cttgagtttt caaataaaac cttgatttcc actataacat ctcctttcac atgaacgtgt
      661 attcatatat tgtagcacat taagttctat tttttgttgt aattaccgaa aaaaatatta
      721 atggacgctt tttacgcttt atttcgtatg tggaagaaaa tttcttagga tgtggcgggg
      781 gattggggca aagctaaatt ccaattacag tgatcattta attagacacc tttaaatacc
      841 cacactttca tcaacactat aatttaggga aagaaaagtg ttggcatgat atagaaaaac
      901 ctttaattaa cagcgtttcc taaaattggc acgcatcttg cttatagaaa agcgtaagga
      961 taggaggaat gaaaatggca actataattc ttgccagcca tggggaattt gctcaaggat
     1021 taaagcaaac agctacaatg attattggag atagtgtacc aattcatgcc ttgtcagcat
     1081 ttagagatga agatgaatct attttggtac aaataaaaaa acttttagcc acaatagata
     1141 tagaagaaac ctacatttta actgatattc taggtggtag tgtgaataat gatatgctca
     1201 ctattattaa agagtatgag ggattgcaat taattactgg aatgaactta cctttagtta
     1261 tttctattgc aacctataat ggaaaaattg gggaaagtga gctagaaaag cttattaaag
     1321 agagtcaaca atcagtgatt gattgtagaa aattattagt agaacaactt actggaggag
     1381 atgacctatg attaagttag tacgtattga ccatcgtttg ttgcacggac aggtagtatt
     1441 ttcttggagt aaatcattaa atatcaatcg tattattatt gccaataaag aggcagcgaa
     1501 tgatgaattc aaaaaaatgt ctttgaattt atctaaaccg actggcatta aattaacaat
     1561 tttttcagtt gaacagttac tagaaaaaat gcctaaaatc gaaacactta acgaaaatat
     1621 catgcttatt tttggtaata caaaagaaat tcgtcaattt tgtgaagcct atcctaaagt
     1681 acaagaaatc aactatggag ggataatcaa aaaagaaggt tccaagcaat ttagtaatgc
     1741 cattttcttg aatgaatctg agcaagaaga tgccaaaaaa ttaaaagctc ttggcattaa
     1801 acaatttatt caacaggtac caacttctaa aaaagaagat ttgaatacaa tgttataaag
     1861 gaggaatgaa aatgctcgtt cagtcaattg gtttagggtt aatcggtgtt ttttgtattt
     1921 tagactcaag gcttttagga agaatgaatt ttgaacgacc gttgattgtc agtacgcttg
     1981 ttggtttggt acttggagac atggaaaaag gattaattgt tggagcctct ttggaattga
     2041 tgtccttagg attagtaaat atcggagctg ctgcaccacc tgatatgaat atggcatcaa
     2101 ttattgctac agcctttgcc attttatcaa atgcgaatgc agaagcagca ttaacgattg
     2161 ccattccaat ttcagtgtta ggtcaaatac taggtatctt aatgcggacg attttgtcaa
     2221 atttgactca cgttgcggat cgctttatcg aacaagggaa atttagccaa gcaaggagaa
     2281 ttcatatact ttatggctcg ggattatatg ctctcatgta ttttattcct atttttctag
     2341 caatttattt tggaacgaat cttgtttctc agattgttga tgcgattcct gagtggctaa
     2401 caaatggctt aacggttgca agtaaaattt taccagcata tgggtttgcg ttgttattac
     2461 aaacgatgtt aacgaaaaaa atggtgccat ttttattact tggattttta attactgctt
     2521 attctggatt gggaatcatt ggtattgcag ccttcgcatg tattgttgcg tttgtcatgg
     2581 ttcaagttca aggtaaaaac tcaaatggta accaaaatga gccagatcca ttagatgact
     2641 tataaggagg tagattaagt gaaagagaaa gatcaaaatg catggaaata tcggcagttc
     2701 ttatggcgtt catgggcaat tcaagcctca tggaactatg aacgacaaat gaacatgggt
     2761 tttatgtacg gaattgcacc aattctagat aacatttaca agaatccaga agatgaagca
     2821 atgaagaaag aagcttacga gcggcatatg atgtactaca actgtacccc tcaaacaagt
     2881 gcatttgtgt tagggttaac tgcttctatg gaggagcaat actacgaaga ccaagaaaac
     2941 tttaatccgg aatcaatcag tgcagtgaag acttctctga tgggaccgct atctggtgtt
     3001 ggtgattctt tctttcaagg aacgattcgg gtattagcct ttggactagg aattaattta
     3061 gcccaacaag gtagtatttt aggtccaatt ctagcaatgt taatttcctt tgtaccttcc
     3121 tttttagtta cttactatgg tgggaaaatt ggctataaca tggggaataa atacttgtct
     3181 aaactgtatc aagaaggttt gatggataaa gtaatgtatg tttgctccat tgtggggttg
     3241 atggtcattg gttcgatgat tgccagcatg atcgggatta caacaccaat tcaaatgggt
     3301 aaagcttttg tcttacaaga tgtattagat agtattatgc cacaattttt accattagga
     3361 ttaaccttct tcatgtactg gttattgcag aaaaaggtca aaacaggatg gatgttggca
     3421 atctgtttag tcggaggaat tatttttagt ttgttaggta tcttacaata agggaataac
     3481 caataaattt ggttgaataa tataaataag gaggaattca attgatgaat tcaaaagaaa
     3541 ttgttaaaga aatcgtagcg aaaaaagagg taaaatcaat cgtatttgtt ggctgtggcg
     3601 cttcaaaagc ggacctttat cctgcaaagt attttctaga ccaaaatgcg aagcagttac
     3661 ggattagtca ttacacagcc agcgaattta actatgcaac accagcatct gtagatgagt
     3721 caactgtcgt tatttcagct tctttaggag gtacgactcc agaaacagtt gaagctaacg
     3781 cagtagctaa agaaaaaggt gctacagtta ttagtctaac acgaagcatt gactcaccgt
     3841 taacaaaaga tgcagattat gtaatttatc atcgatttgc agagaactat gctgctaaat
     3901 tagaaaaaac aggctactgt ttagaattgg cagtagaact tttacatcaa gtagaaggtt
     3961 atgaccatta tgaagcaatg caagaaggat ttgctactat ctatgatctt gcccaaaaaa
     4021 gtgcagaatc agctcgtaaa gatgcgaaga aatttgctga acgctttaaa gatgaaaaag
     4081 ttatttatgt aatgagtagt ggtgctacac atgaagtagc atactcaaca tcaatttgct
     4141 tgatgatgga aatgcaatgg attaattctg gtaccttcca ttcaggagaa tttttccacg
     4201 gaccattcga aattgtggat aaagacgtac cgtttatatt attaatgaat gatggaaaaa
     4261 ctagaaatat agatgctcga gcattaactt tccttgaacg ctttgatacg aaaacagaag
     4321 ttgtagatgc cttggattat ggcttgtctt cacatattgc taaagaagtc ttagactact
     4381 ttaacccatt cgtgattact gcagtattta gagtttatgc agaagaattg tcagaagcaa
     4441 gagaacatcc attaactaag agacgttata tgtggaaact aacttattaa aaaatagatc
     4501 aaactaaata aggtggcttg agaaattaag ccaccttgtt ttcttcaatg tgattttata
     4561 catatggtaa aataactagt acatattgtg aaagcaggtg gcaagatgca gcgattaaat
     4621 gactatcttt atcaactaac attgcttttg aaatctacgc cttcagataa ttattcagct
     4681 cgcagtattt cgcaagcttt acagttgaat agaagtacaa tcagtagcta cttaaatgaa
     4741 ggtgttcgtg aagggctttt cataaaagta aaaagttacc cggttttatt tttacataga
     4801 acagctcttg aagaactaca tatcacactg aataactccg aaatagaatc aattgaaagc
     4861 ttgttaacaa tttctcaaaa acccgcatta gatcaagtaa ttggctctaa aggaagtttg
     4921 aaagaagcaa ttgatcaaat taaaacggca gtcttatatc ctggaaaagg gttgccttta
     4981 ttattgatcg gcgctagtgg atcagggaaa acctttctag cgaataaaat atatgaatat
     5041 gcagtagaag aaaaggtcat tcacacatcg gcacctttca tagattataa ttgtgcacaa
     5101 tatgtgagca atccagagtt actatcctct gctttatttg gctacacgaa aggagcattt
     5161 accggagcaa gccaggagca tactggtttg ctagaaaaag ccgatggagg agtattgttt
     5221 ttagatgaag tgcatcgctt atctgaagaa gggcaagaga aattatttac atttatggat
     5281 acgggtgaat tctctcctat gggggataat agtattcgga aaaaagccga tgttcgatta
     5341 gtctttgcaa caacagaaaa tatatatacg actttcttac caacttttct taggagattg
     5401 ccagttattg ttaatctacc tagatttcaa caacgtccgt cgtttgaacg tctgtcattg
     5461 attgatgaat tttttgtttc tgagagtaaa attttagcta aggaactatc tgtttctgat
     5521 gcattgattc atttcttaat gaatagtgat tttgaaggta acgtggggaa tattaaaaat
     5581 attatcaagt atgcttgcgg aaacgcatat atccaccaga agagtcagca aacaattcaa
     5641 gttaaattat tggatatgcc tttagagtac agttataaat tcaaggagca actaaataaa
     5701 cccagaaaga aaagagcaga tcgaatctac tatccagaag aaacacgaca agtgcaacta
     5761 gaaagaaaca atcagctttt tgttcaattt tttgaccaat tacttactgg attctctgaa
     5821 gtgattgaaa ataacaagga tattaaacta tttttagaag aaatggttac caaggtaaca
     5881 caagtaatgg atacgcttat ttttcaagag gattacgaaa aagagcagtc tttatacgcc
     5941 attctaaact atcatattcg tcaaagtatt gattttatgc gagaaagcta cgggtttgaa
     6001 caagatggta accgggtagt cgctttggcc aactatctat atgtcaagga taatcaagtg
     6061 atttttgaaa atagtcttca agaaaagaaa accaaagatc agcttaacga attttttgct
     6121 aatgttcttg aaacccctta ttggtatgca aaaaaaatct taagcctttt atctgagtgt
     6181 ttagatcaac ctgtgtatga agaggacatt ttctttatta cgctatattt ttatagtttg
     6241 aatgtcacga atgttaaaac aggtattaag agtattgtgc tagctcatgg ttattctaca
     6301 gctagtagta tggcgaatgt tgccaaccgt atgctgaata agaacgtttt tcaagcttat
     6361 gatatgcctt tagatattac attagagaaa attgaagcaa aattgattca attccttgga
     6421 gattatcgaa cagattcagg cttgatttta ttggtagata tgggttcact aaaccaacta
     6481 ggcggtttat tagtgaatca tctaaatgga ccactgttaa tcattgatca tatcaataca
     6541 ccgttattat tggaagtcgg ccaacaagta ttaaacaata aaagtatcac cgaaatagga
     6601 gcagaaattg aaacaagtct tactttcaaa aagcagttac tacttcccaa gaaaaagaaa
     6661 aagaaagcca tcattacttg ttgttataca gggattggta gtgcgaccca gattcaggag
     6721 attttaacga aatgcttgaa agatgcagtt agagaattag taattattcc gtatgattac
     6781 aaaaagctgt tagaaaacaa gaattttgag actccttttc aattatacga tgtcatcatg
     6841 attgtaggta cagaagatcc caaaattaat cagattccat atattggatt agatcgcctg
     6901 attaatgggg aagcaattgg cgaatttgtt cattacttgg aaaaagagct gactattgaa
     6961 gtgaacgatt tacaaaaaga attaattttc aatttttcaa ttagtaaaat tgtcgaaaat
     7021 ttaaccattt tggatccaga taaggtgcta tcttttgtac aaaaagcaat taaagaatta
     7081 tcgaagttat taaattttga tttttctaat aatcagctgt ttttgttgta ccttcactgt
     7141 agttgtatga ttgaacgaat tgtacgtaaa gaaagtgtgg atgagcaaga ggacattgaa
     7201 gaatatatgc aagcaaatgg agaaataatg gataaaattc atagcgcttt ttttgagatt
     7261 gaaagggaat acacaattga aataccagat ttagagttgc gattattgag cgatattgtt
     7321 caaggatagg agtgaattcg aatgacaatg ggagtaattt ttgatatgga tggggtactc
     7381 atagacagcg agacatttta ttttgagaga agaatgaact tctttcaaga actggagata
     7441 gatccaggat caaaccagat tgatgattat gtggggaaaa cagaagctgc aatatgggaa
     7501 acattagttc ctgaggacaa atcattaaga gaggaacttt atccgaaata tgtagattat
     7561 cgaaaaacgc atccaattga tttcgctaaa gatttacgaa aagaagtgaa accgttactt
     7621 gacttcctca agaagcggga tataccattg gcactggcat cttcttctcc agttgttgag
     7681 atagagagta tgctcattca atgtgaactt actgaatatt tttcctttgt tataagtggt
     7741 gagtcattaa aacaaagcaa accacatccc gaaatatatt taaaagcgaa acagcaatta
     7801 gactgtgact tctttattgc agtagaggat tcaacgattg gtattaaatc agcaaaggca
     7861 gcaaatatct atacggtggc actaaaacaa ccaatgcaaa tcgatcagag tgaagcagac
     7921 atacaaattg aaagtctaca agaactggaa caaattgttt tagaaaaagg ttagtgaatt
     7981 aatggaaata aggctatata tctgtgctag ctattttgac taaccaaaaa aacttgctat
     8041 aattcaggtg tagtaaaagg tgctggtaac accttttacg aaaatgcttc ggcagtgata
     8101 atgggattgg ctttttaagt tttttatttt gttcgcaatc cctaaggtca tgtgaatgat
     8161 cctagggatt gctagaatat tttgcaacat tctatctatt tcagaacgta accttcccca
     8221 gttcattggg attcattagc atacaaccaa catttcaaaa agaaattgca ctacaccatt
     8281 attagctatt ttgactaacc ccaaaaaact tgctataatt caggtgtagg taaaaggtgc
     8341 tggtatcacc ttttacgaaa ctgcttcggc agtggtaatg agtgtggctt aaaggactag
     8401 tcctttaagc tttttacttt gttcgcaatc tctaagatca agttaatgat cgataagatt
     8461 gctagaatat tttgcaacat tctatttcag aacgtaacct ttcccattcc actgtgattc
     8521 attggcaacc ctcctcacaa ccaacgtttc aaaagaaatt gtaaagttgt tggggtacca
     8581 cgaccgaaca atactacacc tgaatgatag taagttgtct cattaagtat agcatatcct
     8641 ctttttgggt aaatagaaat cggttacatt ttttatccaa gaccaagttt tttcatttgg
     8701 tcttatttgc tatacccaaa caattccgca gtatagtcga cggtattgat tttatcaggt
     8761 gagtaataga aacttgtttt ccttccccaa aacattacct ataaaggaga aaaaatggta
     8821 tcgtaattat ataggtatag gatgaaattt ttttctaaga ggagggttgt tgatgaaaaa
     8881 tttacagtta aaatttattg ttgatccatc gattgtacgc tggtttcgga ttatcaatca
     8941 atttgagcgc aatcaacttg ccacaaaagg agaattagca aagagtaatc atgtatctga
     9001 acgaaccatt caaacagatg tcaataaaat gaaggactac ttttctgaaa gtgttcaatt
     9061 tgtttcaacg aaaagtgggt attcttttca gaaggaaaga ccggttcttt ttctcaagca
     9121 gaaggagcaa ctactggaga acgaaatttt atttgagttg ttagggaatg tcttttatgg
     9181 cgaattggaa gatatgacgg agctaattga tcgttttcat ttatctgaag cgacttttcg
     9241 tcggtatttg aagcagattc aaccagtttt ggaagaatac ggcttagaat tgagtcttta
     9301 tcctcttgat ttaaaaggag aagaggcaaa tattcgcaag ttttttaaag acttctatta
     9361 tgaaggggag atgacgcccc atactcttgt tccaccaagg gatcttcatg aacttgtgca
     9421 agctacattc tatgataaat ttgagtattt ctcgattgga acagggactt ctcctgctga
     9481 attttattat agtttgtata ttgcgattga gcgtgtgaga caaggaaaaa cgatagccat
     9541 tcctcaaggt ctgattgagc gagtaattgc tagtgagaat tttcgcttaa tgtattcctt
     9601 gaaagaagcg attcaaacaa attatcaagt tgctttatca gaagaggagt tttgttggtt
     9661 gtattta
//
LOCUS       DAMEEU010000094         9590 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.096, whole genome shotgun sequence.
ACCESSION   DAMEEU010000094 DAMEEU010000000
VERSION     DAMEEU010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.096"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..154
                     /locus_tag="PB779_002494"
     CDS             <1..154
                     /locus_tag="PB779_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDE0739991.1"
                     /translation="NKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTLFGFSVCTEIKV
                     LLGIQA"
     gene            206..352
                     /locus_tag="PB779_002495"
                     /pseudo
     CDS             206..352
                     /locus_tag="PB779_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
     gene            429..758
                     /locus_tag="PB779_002496"
     CDS             429..758
                     /locus_tag="PB779_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDE0739992.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            748..1035
                     /locus_tag="PB779_002497"
     CDS             748..1035
                     /locus_tag="PB779_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDE0739993.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            1321..2178
                     /locus_tag="PB779_002498"
     CDS             1321..2178
                     /locus_tag="PB779_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HDE0739994.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYVEVE"
     gene            2179..2727
                     /locus_tag="PB779_002499"
     CDS             2179..2727
                     /locus_tag="PB779_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0739995.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            2987..3620
                     /locus_tag="PB779_002500"
                     /pseudo
     CDS             2987..3620
                     /locus_tag="PB779_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348804.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
     gene            complement(3665..4614)
                     /locus_tag="PB779_002501"
                     /pseudo
     CDS             complement(3665..4614)
                     /locus_tag="PB779_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300609.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
     gene            5216..7060
                     /locus_tag="PB779_002502"
     CDS             5216..7060
                     /locus_tag="PB779_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0739996.1"
                     /translation="MNYKQTAEEVLQYIGGEENISHLEHCSTRLRFTLKDNSKVNMSQ
                     LEKVDGVMGVRQNVQCQVIIGNDVVEVYDEVKALLGDNVSNTEEAPKQKQKLGSVLLD
                     FIISIFQPLIPAIAGGGVLKSLLLLASILGLISDQSQTYQILNLVGGAPLYFLPILVA
                     MTTANKLKVNQLVAVSAVGALILPEMTAMLAEGATFLSFGLDNIAYASQVFPAILTVL
                     FYAQLEKWFTKVSPKPIRIFFVPMMSLLITVPIALLLLGPLGYNVGTAFSSIIVSLYN
                     QFGWVATGVLAAVLPLMVVTGMHKAMIPYAVSSMSELGAELLYLPASLAHNISEAGAC
                     FAVSIKTKDKKLKSTAVSAGISALFGITEPALYGVTILHKRVLYAVMFSSLIGGAFAG
                     IVALQAFALVGPGIASITMFADKADPMNLVWAFAVSGISFVVAFAAALVLYKDKEVVN
                     EVETKMETAVVSDAVLSSPVNGKVISLSEVKDTVFSSGMVGDGVAIIPEEGILVAPED
                     GEITMVFETKHAIGLKTANGAELLFHIGIDTVQLEGKGFEAFVRSGEKVAKGQKLIAF
                     DIDLIKEAGFDPTVICVVTNKDNYTIRSFNLEKLVTNDSDLLAISPIA"
     gene            7116..8582
                     /locus_tag="PB779_002503"
     CDS             7116..8582
                     /locus_tag="PB779_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016620473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0739997.1"
                     /translation="MTNTTSFPKGFLWGGAIAANQVEGAWNVDGKGLSVADMATYKPN
                     LDNKDFAAHMHVTLQSIKEASEDKSDKWYPKRRGVDFYHHYKEDLALFAEMGFKTLRL
                     SIAWTRLFPTGEELEPNEKGVAFYENVFKEMQRLGIEPIVTLSHYEMPLALAVKYNGW
                     VERRVIDDFVRFANVCFDRFGKYVKYWLTFNEIDSIHRHPFTTAGIIQEKSAEGQEAQ
                     DIYQALHHQFVASALVTKDAHEKIPGSQVGCMLTKLMTYPLTCAPEDVELTLKKNLEN
                     NFYADVQVKGEYPALIEKDLENRGIQIKMEDEDREILKKHTVDFVSFSYYMSMAESAD
                     PNAERTPGNTVLGVKNPHLPSTDWGWQIDPKGLKISLIELYDRYQVPLMIVENGMGAV
                     DQVVDGKIHDPYRIDYFKAHFQQMKEAIDEGVDLIAYTSWGPIDLVSAGTSQMSKRYG
                     FIYVDADDEGNGTYNRLKKDSFNWYKEVIETNGASLFE"
     gene            8619..9461
                     /locus_tag="PB779_002504"
     CDS             8619..9461
                     /locus_tag="PB779_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDE0739998.1"
                     /translation="MISIKKVLNSSVVLVEENGKEMIALGKGIGFGQKAGDEISGDKV
                     DKIFLPFEEKKSSQLLELVEEIPIEFFEITRTIVFEAEKGLDKKLNPGVYLTLTDHLH
                     FAVERAQKGVNIANRLYWEIKIYYPKEFQIGKYALTLLNEQYGIDLPKEEASNIAFHL
                     INAQSEDPDSGAGFKYAKMIGGIVNLVRYSLQKDIDTNSIHYARFITHVRFFVERYYS
                     DALLDDGEEEFYNQMWILYPSAMESAAKIKDYIEKVYHKTIPNDEVVYLGVHINRLMK
                     HANG"
BASE COUNT         3294 a         1474 c         1936 g         2886 t
ORIGIN      
        1 caataaattc tatcgaagtt tacgcactgc ctctaccacg attaaaggca tggaagccat
       61 tcgaggatta tataagaaaa cccgaaaaga aggcactctc ttcgggtttt cggtctgtac
      121 tgaaatcaag gtattattgg gaatccaagc ttaaatcata gataccgtaa gggattttat
      181 tctttattta aaactttgca acagaaccca atcatttgag aagttaaaac ctacacatga
      241 aggtaggtat tttagaagat tgaatagaca acaccgggtt gtttataagg tagatgaaga
      301 tgaacacgtg gttgaaattt attcagcaag gacgcattac gagtcacagt aattacttgt
      361 aaatacatta tctcgtggta taatgtattt actaagtaat tacatactgt tagaaatgag
      421 ggatttaaat gattacaaaa acaagaaaac aaggcaattc aatcatgttg acagtaccta
      481 aagattttaa tgttcctaat ggagtcgaag ttgaagcaaa gttggtagag aatggtattc
      541 tttatgaatt tgttgaacca caaaaagaat tttatgattt tagcgaagat attttgtctg
      601 atataattgc agaaggctac gataaagatg agattcttgt agaatttaag aatagaaaaa
      661 acaaaatgca ttcttccttt agagatattg ctgaagatac acttactaat tctaaagtaa
      721 tgactaaaga ggagttggca acagaaattg gcttatgaaa tcgttccttc aaaacatgtc
      781 attaagtatt taaaaaagct aaaagagaag ccattgaaag aaaaattttt gaatttaatt
      841 tatgatgaaa ttgcgattga tccatataag ggtgaacaaa aaactgggga tttatcaggt
      901 atttggtcta gtgggttcaa atatgcgggc acaacatata gagtagctta cgagattata
      961 gaaaacaagg ttattccagt attgttatgt ggaacgcatg aaaactttta tgaacagttg
     1021 aaaaaattaa tctagtgatt tgttgtcgtt cttaagaagg acggcttctt ttttatcgaa
     1081 aatctgattc gtctacatga ctaaagtcgc gagtattctc tgcttctcga taaattaaat
     1141 aacgtcatta ctttgaggaa agctataaat caatatattt cagcttttcc ttatttatgt
     1201 actacctttt acttattaat tataaggtag tacatatata tctttttttt ggtagtaact
     1261 aaaaataaat atgttataat agtatcaaat gaatattgct aaaagaaaag aggtaggaac
     1321 gtggtagcga agaaatatgt aatcggtaat tttaaaggtg gcgtaggtaa aagtacgtgc
     1381 gcgcaaatgt tagggtttga atcagcagtt aatgaaggaa aaagaacctt gataattgac
     1441 ttggatatgc aaggaaatac ttctgatgtg atgaacttaa cgcatatgaa cttcactaac
     1501 gaagaaggag gcggagaagg tgaaccgatt gtttacgaaa atactgtgac tgacgtgttg
     1561 ataaacaatc ttccacctaa agaggctgtc tataaagtaa tcaataacct ctatatactt
     1621 ccagcagaca tgtcctttga aatgtatgat gattggatca aagaccaata taatgattca
     1681 ttatcccaat tcaaatatat gaaagaaaag ctagaaccat tatttgatga gtttgacgtc
     1741 atctatttag atgtcccacc ttctatttct gtatatagta aatccgcgat gtacattgcg
     1801 gattgggcaa tcgtcgtctt acagacccaa gtaaaatcga tgagaaatgc gatgcaatat
     1861 cttgagtata tggacttttt tgtgaaagaa tttgatacaa atttatatgt tgctggtgtt
     1921 attcctttca tgttggaaag cggtgacgca gtagatcagg aaatgtataa acaagcccaa
     1981 gagatttatg gggaacattt gattaaaaat gttgtactca aaaatgcgcg cttaaaacga
     2041 tacgacggat caggtattac gatggagaag acaaagaaag gtctcttaaa acaatgggat
     2101 cgcaaaagcc acgaattatt tatcagtatt ttgaaagaat tggaagaaca cgagaattgg
     2161 tatgtggagg tggagtaatt ggctgacatc aaaggacttg atatttttgg gaacaacaaa
     2221 ggactcgcca aaataaaaaa agaagcagaa gcaaagaaaa agcagcaagc aattacacca
     2281 tctgaaaata agcaattaga agtgcaccaa gttcaagaaa taaaaacttc ctccaatgtt
     2341 gaaagacaga gtagaggaag aacaaaaaaa gttggcgcac caatcagaaa gtttgataag
     2401 gtttattcca ccaagcatcc tttaaaactg tcgactttgt taaatgcgac ttccagagtt
     2461 ttagtagaaa agtatgagac taatatgaca agagatgaat tgcttagaaa agctttagat
     2521 gagtatatta aacagaatct tacgcaagaa gataaacaag atttgtttaa tgacgtggtg
     2581 aaagaactag acttgttcag agaaaaatat ccaattgttc cagaattaga tgatcgtgga
     2641 gaaataataa gaactaccag tcagataaaa caagataccg aagactcact gcgcaaaggg
     2701 tggggaatga ataataaagt tagataataa tcaaagaaga actaagtaac tacctttaaa
     2761 cggtagttac ttagttcttc tttgatttgc gtgaaataga ggggatttat ttttctggtt
     2821 acgtgattaa aaaatccaaa aaatgagcat aggaacggtt atgattttag ggtgtgtttt
     2881 aatgagatat tgtgatttca ttaataagtg tatgataatc tgttgttgag ttagtaaata
     2941 agtaatagag ctaactctaa aataaaacta ttaggaggag atgtagatga aaaagtttaa
     3001 aaagaaaata tatttaggat tggttgttgg ggtgagtatg tttgggttca tggctcatac
     3061 taaacaagta actgcagata ctaaccaaaa agaaaggatt atgagccaat tagatgactc
     3121 tcaaatagag tatgtaccca atgagctaat tgtcagttta aaggctacac aaagaatttc
     3181 aacagagaaa aataaaccgc aaaatttatt gggtgtaaaa gttatggtgg aaaaagattt
     3241 gactcttagg acaaatgaaa gcgattataa taagcgagat caagtattat tagtgaaatt
     3301 gaacgaagaa attagtgtgg aagaggcagt aagaacattt aatgcttctg atatggtcaa
     3361 ttatgcagag ccaaactatg tggttgaact agagccgttg aatgatgttg aggagccaaa
     3421 tacaactgat tctttaggaa atcgataacg atcctaattg gagtaaacaa gctaatttaa
     3481 gagagattag catgccatcc gcttgggaag aaaccaaggg ttctaaggat gtgaaggtag
     3541 cggtcattga ttcaggaatt gattatcaac atgaagatct ttctggaaat gtagatgaaa
     3601 gtttgggata cgattttttt tacttttttc aagaaaataa taattcagaa tattctgact
     3661 atatttatgc aacactagtg actttaggag aaacatcaat agccttgcta aagtttttgc
     3721 tttcgctaaa gagagtattt tcgataattt gtttttttct aaaatacctc gttcctcaat
     3781 atttgggata tggatatgta tagggattct tcgcataaag gtttccagaa aatcctcttt
     3841 gccttctgta gtcgcaaaaa ctaaacgtac attggaggcg tgatggatag tttcaccgac
     3901 tctagaataa gttccgccat ccatataaac aaatagtttc tcttgccctt caggaggcaa
     3961 tctgtgtact tcgtctaaaa acagtactcc accgtctgca tcttgcaaca atccatttcg
     4021 atcttcatct gcgccggtaa aagcaccttt aacatagcca aatagtatcc ccgacaataa
     4081 ttcaggatta ttatggtatt gcgcacaatt aagtacttta aaaggagcat tctcatgaat
     4141 aacgttcact tttttcataa actgataagc agtatgaaca aaaaaacttt ttccaactcc
     4201 agtatctcca gtgatcatca taggaagccc tcttccagga tagaagacag cagttttcat
     4261 ttgttccacc gcatcggata agctcatatc atacccaatc atcttttgta gaatggaatc
     4321 tgtagaattg ggccccaagt ctgtttttaa ttcagatata ctttcgtata catcttttac
     4381 cggaatcaaa aagtgctctt caaagcgctc tttgatggca aataacactg gacgagtatt
     4441 gattttaaat agaacgttct ttgcaactaa gtcattggca agtttactgg catttgttct
     4501 tcccgttctt aaaaattgcg acaggtcatt tgtgtcaaaa aagcactctt ctaaattact
     4561 gatgccaatt tcttcacatt ttgtgtttgc ataagtcact atatcatttt tcatcttata
     4621 aacagtcctt tctaaacttc tatcccttaa ataaatagca aaaaaaagga agcaatatcg
     4681 atatgctgtc ctcttaattt aataaagcgc taatctaatt cactgtatta tcatttttta
     4741 gtagtatagc acaattatga atgccttttc tttatatcaa ataaagttta tataaaaaac
     4801 ctcatcctgc aagaaagaaa aaatgaaccc attcttttta tactaggtct taaaaagaca
     4861 gaacatctgc tagaagatag aagagaataa gagttatata tgttggaaga tattcttaga
     4921 aaaaagacaa aacttttaga acacgaaaac tatattgaac gaataaaatg aaaaaatgat
     4981 taaaaaatca ttttattatt tacgtttaca ttctaatatg ttaaattgaa tataacttaa
     5041 acaggcatgt gactggtaat gcaggcagga cctaaataag ttgaataaca atgtatgcgt
     5101 ttcaatacac gtttgccttg ttgtcaattt atttagtttc tgcctgtttt ttgtgttgag
     5161 gatggccact tcgactcaaa agttcatcac tcaaaaaaga aaagagggaa acaccatgaa
     5221 ttacaaacaa acagcagaag aagtattgca gtacatcggt ggggaagaaa acatatccca
     5281 tttggagcat tgctcaactc gtttacgttt tacgttaaaa gacaacagca aggtaaatat
     5341 gagccagtta gaaaaagtgg atggcgttat gggcgttcgc caaaatgtgc aatgccaagt
     5401 aatcattgga aacgatgttg ttgaagtgta tgatgaagtg aaagcgttat taggtgacaa
     5461 tgtttcaaat actgaagaag caccaaaaca aaaacaaaaa ttaggttcag ttctattaga
     5521 ttttattatt tctattttcc aacctttaat tcctgcgatt gcaggtggag gagtattgaa
     5581 gtccttgttg ctactagctt ctatcttagg gctgattagt gaccaatctc aaacctatca
     5641 gattttaaat ttggtcggcg gggcaccgct ttatttcttg cctattctgg tggcaatgac
     5701 tacggctaat aaattgaaag tcaatcaatt ggttgcagta tctgctgtcg gtgcattgat
     5761 ccttcctgaa atgacagcta tgttggcgga aggtgctaca ttcttatctt ttggattgga
     5821 taatatagcg tatgcatctc aagtattccc agccatctta actgttttat tttatgctca
     5881 acttgaaaaa tggtttacaa aagtttcacc aaaaccaatt cgtattttct ttgtacctat
     5941 gatgagctta ttgattacag ttcctattgc tttgttgctt ctaggaccat taggttataa
     6001 tgtaggaaca gctttctctt ctatcattgt gtctttgtac aatcaatttg gatgggttgc
     6061 aaccggagtc ttagcagctg tactgccatt aatggttgta acgggtatgc ataaagcaat
     6121 gatcccttac gctgtttcat ccatgagtga attgggtgca gaacttcttt atctcccggc
     6181 ttcattggca cacaatattt cagaagctgg cgcatgcttt gctgtcagta tcaaaacaaa
     6241 agacaaaaaa ttgaaatcta cggctgtttc tgcgggtata tctgcattat tcggaattac
     6301 tgaaccagct ctttacgggg taacgattct gcacaaacgt gttttatatg ccgttatgtt
     6361 ttctagcctg atcgggggag catttgcagg aatcgttgca cttcaagcct ttgctttagt
     6421 gggtcctggg attgcaagta tcacgatgtt cgctgacaaa gctgacccaa tgaatctggt
     6481 ttgggcattt gcagtatcgg ggatttcatt tgtggttgct tttgctgcag cgttggttct
     6541 ttataaagat aaagaagttg tcaatgaagt tgaaactaag atggaaacgg ccgttgtttc
     6601 agatgctgtt ctttcaagtc ccgtgaatgg aaaagtaatc tcactatcag aagtaaaaga
     6661 cactgttttt tctagtggta tggtaggtga tggagtagca atcattcctg aagaagggat
     6721 attagtagct cctgaagatg gagaaatcac aatggtattt gaaacgaagc atgctattgg
     6781 tttaaaaacg gctaatggtg cagaacttct ttttcatatt ggtattgata ctgttcagtt
     6841 agaaggaaaa gggtttgagg catttgttcg ttctggtgaa aaagtagcca aaggacaaaa
     6901 gctgattgca tttgatattg atttaatcaa agaagcagga ttcgacccca cagttatctg
     6961 tgtggtaacc aataaggata attacactat ccgttcattt aacctagaaa aattggtaac
     7021 caatgatagt gatctcttag ctatcagtcc gatagcttaa acacaagata gtgaaaaaaa
     7081 atatattgaa tgaaggaata gaggagaata gaataatgac aaacacaaca agttttccaa
     7141 aaggattttt atggggcggc gcgatagcag caaatcaagt agaaggtgct tggaatgtag
     7201 acggtaaagg tctttcagta gcggatatgg ctacttataa accaaattta gacaacaaag
     7261 attttgctgc tcatatgcat gtcaccctgc agtctataaa agaagctagt gaagacaaat
     7321 ctgataaatg gtacccaaaa agaaggggcg ttgattttta tcatcactat aaagaagatt
     7381 tagctttatt tgccgaaatg ggctttaaaa ccttgcgcct ctctattgct tggactcgct
     7441 tgttccctac aggagaagag ctggaaccga atgaaaaagg ggttgcattt tatgaaaacg
     7501 tctttaaaga aatgcaacgt ttaggaattg agccgattgt gacactatct cattatgaaa
     7561 tgccattagc tttagcagtt aaatataatg gctgggtgga gcgtcgagta attgatgatt
     7621 ttgttcgctt cgctaacgtt tgttttgatc gcttcggcaa atacgtaaaa tattggctga
     7681 catttaatga gatagacagc atccaccgtc atccatttac aacagctgga attatccaag
     7741 agaaaagcgc agaaggtcaa gaagctcaag atatctatca agcattgcat catcaatttg
     7801 ttgcgagtgc gttagtgaca aaagatgctc atgaaaaaat tccaggaagc caagttggtt
     7861 gtatgttaac gaaattgatg acttatccat taacttgcgc accagaagac gttgagctga
     7921 ccttgaaaaa gaacttagaa aataattttt atgcagatgt tcaagttaag ggagaatatc
     7981 ctgctctaat cgaaaaggat ttggaaaatc ggggaattca gattaaaatg gaagatgaag
     8041 atcgagaaat tttaaagaaa cataccgtag attttgtttc tttcagctat tacatgtcca
     8101 tggcagaatc agctgatcca aacgcagaac gcacaccggg aaatactgtt ttaggggtta
     8161 agaatcctca tttgccttca acagattggg gctggcaaat cgatccaaaa ggtttgaaaa
     8221 tttcgttgat cgaactttat gatcgttacc aagtaccgtt gatgattgtg gaaaatggta
     8281 tgggagcagt cgatcaggta gtagatggta aaatccatga tccgtaccgc atcgactact
     8341 ttaaagcaca cttccaacaa atgaaagaag caatcgatga aggtgtagat ttgatagctt
     8401 atactagctg gggaccaatt gatttagtta gtgcaggaac ttctcaaatg tctaaacgat
     8461 atggatttat ttatgtggat gcagacgatg aaggaaatgg gacatataac cgcttgaaaa
     8521 aggattcgtt caactggtac aaagaagtga tcgaaacaaa cggtgcatcc ttattcgagt
     8581 agtctcgatc tttttaagca gcgatagggg gataatgagt gatttcaata aaaaaagtat
     8641 tgaattcaag tgtggtactt gttgaagaaa atggcaaaga aatgattgca ttaggtaaag
     8701 ggataggctt tggacagaaa gctggggatg aaatatcagg agataaagta gataaaatat
     8761 ttctgccttt tgaagaaaag aaatcttcac aactattaga gttagttgaa gaaataccta
     8821 ttgaattttt tgaaatcact cgtactatcg tttttgaagc agaaaaagga ttagataaaa
     8881 aactgaatcc tggagtctat ttaaccttaa cagaccacct gcattttgca gttgaacgcg
     8941 cacaaaaagg ggtaaatatt gcaaaccgtt tgtactggga aataaaaatc tactatccca
     9001 aagaatttca aattgggaag tacgcactca cccttttgaa cgagcaatat ggaattgatc
     9061 ttcctaaaga ggaagcctca aacattgctt tccatttgat caatgcacaa tcggaagatc
     9121 ctgatagcgg cgctggattc aagtatgcaa aaatgatcgg cgggatcgtc aatttggtcc
     9181 ggtattcgtt gcagaaagat atcgatacta attcgatcca ttatgcccgc ttcattacac
     9241 atgtacgttt ctttgtagaa agatattatt ctgatgcttt gttggatgat ggtgaggaag
     9301 aattctacaa tcaaatgtgg atcttatacc cgtctgccat ggaaagcgca gctaagatca
     9361 aagactacat tgaaaaagtt tatcataaaa caattccgaa cgatgaagtt gtatacctag
     9421 gtgtccacat caatcggttg atgaaacatg ctaatgggtg agcgctcagt aatactattg
     9481 atgcttttaa aatctttaga gatggattat agtaaaaaca aggtgatttc cagctgtttg
     9541 ttatctataa gagacattta aaaaggatta acgtaagata ataaaaaatc
//
LOCUS       DAMEEU010000095         9287 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.097, whole genome shotgun sequence.
ACCESSION   DAMEEU010000095 DAMEEU010000000
VERSION     DAMEEU010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.097"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..497
                     /locus_tag="PB779_002505"
     CDS             <1..497
                     /locus_tag="PB779_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDE0739999.1"
                     /translation="RLLKQYRTQGWTEFSKEKFFDLLDIPKSYWNSPSNIDKFILRPI
                     KEELTPLFKGLTIRKKYGKGRGKPVIGYRFTWKAEINHADDFSKGKQEDLRIKLFNID
                     HNGELTREEKWRAKDRILNLPLGTHEADFKQQQQTEEKQAEKRELSNKLKQDLLGNLQ
                     NLFD"
     gene            513..1052
                     /locus_tag="PB779_002506"
     CDS             513..1052
                     /locus_tag="PB779_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDE0740000.1"
                     /translation="MADKTIKELAEELGVSKTAINKKVSDKNRKLWFAKNGNKFVINE
                     TGQKAIKSMFLVDNANLNRKLVGEKSKTKNHKNTNQVSELKLLSFLEKQLNRKDIQLQ
                     EKDNQIKQMQKLLDQQQQLTLQANQQIENLQEQLHLTYTEETPTTESTAFSEKKADNT
                     QPLIEKKWWQIWKSNRTNL"
     gene            1733..1906
                     /locus_tag="PB779_002507"
     CDS             1733..1906
                     /locus_tag="PB779_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740001.1"
                     /translation="MLKKTVLVLGSISLGILGFSPMLLSVIGKNNSNRELKLNSNYYN
                     SPNEELFVKETDK"
     gene            2356..2580
                     /locus_tag="PB779_002508"
     CDS             2356..2580
                     /locus_tag="PB779_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HDE0740002.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            2600..2887
                     /locus_tag="PB779_002509"
     CDS             2600..2887
                     /locus_tag="PB779_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDE0740003.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            3337..3717
                     /locus_tag="PB779_002510"
     CDS             3337..3717
                     /locus_tag="PB779_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDE0740004.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            3699..4613
                     /locus_tag="PB779_002511"
     CDS             3699..4613
                     /locus_tag="PB779_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDE0740005.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            4853..5542
                     /locus_tag="PB779_002512"
     CDS             4853..5542
                     /locus_tag="PB779_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740006.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQVLAQKIEKFTA
                     CYEDMNDIFVKQEKRLTDKNMETLTRLYRNLPEEQQKEYQEKYEQVKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(5662..5748)
                     /locus_tag="PB779_002513"
     CDS             complement(5662..5748)
                     /locus_tag="PB779_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDE0740007.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            6394..7326
                     /locus_tag="PB779_002514"
     CDS             6394..7326
                     /locus_tag="PB779_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDE0740008.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            7343..7813
                     /locus_tag="PB779_002515"
     CDS             7343..7813
                     /locus_tag="PB779_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDE0740009.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            7897..8201
                     /locus_tag="PB779_002516"
                     /pseudo
     CDS             7897..8201
                     /locus_tag="PB779_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            8476..>9287
                     /locus_tag="PB779_002517"
     CDS             8476..>9287
                     /locus_tag="PB779_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HDE0740010.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTG"
BASE COUNT         3539 a         1452 c         1587 g         2709 t
ORIGIN      
        1 ttcgattatt aaaacaatat cgaactcaag gctggactga attttccaaa gaaaaatttt
       61 ttgatttact agatattcct aaaagttatt ggaatagtcc gtcaaatatt gacaaattta
      121 tcttaaggcc aattaaagaa gaactcactc ccttatttaa aggattaact attcgtaaaa
      181 aatatggtaa aggtcgaggt aaacctgtta tcggttatcg ttttacttgg aaagctgaaa
      241 ttaaccatgc tgacgatttt tccaaaggga aacaagaaga tttacgtata aaattattta
      301 atattgatca caatggagaa ttaacacgag aagaaaaatg gcgcgctaaa gatcgaatac
      361 taaatcttcc cttaggcact catgaagctg attttaaaca acaacaacaa actgaagaaa
      421 aacaggcaga aaaacgagaa ctttcaaaca aactcaaaca agatttacta ggaaatttac
      481 aaaacttatt cgattaagct taaggagtat ttatggcaga taaaacaatc aaagaacttg
      541 cggaagaatt aggagttagt aaaacagcaa ttaacaaaaa agtttctgac aaaaatcgaa
      601 aactttggtt tgcaaaaaac ggaaacaagt ttgtgattaa cgaaaccggt caaaaagcta
      661 taaaatcaat gtttttagtc gataacgcaa acttaaatcg aaaactagtt ggcgaaaaat
      721 caaaaaccaa aaaccataaa aacaccaacc aagtttccga attaaaactc ctttctttcc
      781 tagaaaaaca gttaaatcga aaagatatac agctacaaga aaaagataat caaataaaac
      841 aaatgcaaaa attactcgac cagcaacaac aactcactct acaagcgaac caacaaattg
      901 agaacctaca agaacagctc catttaactt atacagaaga aactccaaca accgaatcaa
      961 ctgccttttc tgaaaaaaaa gcagacaata cacaaccact tattgaaaaa aagtggtggc
     1021 aaatttggaa atctaataga accaatctct aaaattttct agaagttagt tcggatagta
     1081 gaggaaaaag ttgtactacc tgatggggag atcactcaaa tttttatgag aaagaaaaaa
     1141 tagtttacaa ctgtaaacaa tcaatgttta tagttgtaaa ctatcaaact atatggtgac
     1201 ttattgctta aaataggttg aaatctcact caatttttgg tggaaaaaca aaataaattc
     1261 taatcgattt tgttgaaaaa gtcataaaaa aacaaatgtg attttaacaa aatttcaaaa
     1321 aaatcgtttg aaatttcgtt tatttttttt gagaattttg atcatcgtag ggtcattgta
     1381 gaatcattat gagatcatcg tgggatcatc gaataaagta tgggaaaggc ttgcggtgct
     1441 tggtattaag ggcattctcc gcctcccagg ttcttgacca ttttctctta taagtgggat
     1501 ttttaccacg ttgagagaaa atggtcaaga acctgggagg cggagaaaac ataccaagca
     1561 ccacaagcaa aaaaagttag agtaacttcc aaaaaagaaa aattttttag aacaactttt
     1621 gaaaatttaa ttttgattta tatccgttca atttaaacat ttgataaact gaaggctagt
     1681 atttaaaatg tgtatacaag tggtagcgtt aaaaaaagtg gaggtataac ctatgttaaa
     1741 aaaaactgtg ttggtactgg gttctatttc tctaggaata ttaggtttta gccccatgct
     1801 attatccgta attggaaaaa acaattccaa cagagaactt aaattgaatt caaattatta
     1861 caacagtcct aacgaagaat tgtttgtaaa agaaacggat aaataataaa aaagactgct
     1921 cttccgagca gccagttaaa aaataatgag tgtttattct tgaaaaagca acgcgcttat
     1981 aaagcgctac caaaaattta tcatatttta tgaaaaataa caatccagta aaaaatgact
     2041 ggtaaaaatt cacaaagaaa cggaaagaag caactgcaga aaatcaagcc ttaaaaagag
     2101 ctttttacct agaccaatta aaaatcacaa agtgagcccc tgtatcggtt gatacaaggg
     2161 ctacttggca tactgtacat tatgtctact agctgtttaa ataactgatc ttataatttt
     2221 atttaaacga ttatgaattc aaaactactt tttatgacgt taatcattgt tatataataa
     2281 aatgttatat aataaaatta ctaagattat ttaatataac aagcaatttt aaaaaaacga
     2341 aaaggaaaaa caatcatgaa aaagaaagta ttaaaacatt gtgttattct aggaatatta
     2401 ggaacttgtc tagctggcat cggtacagga ataaaagttg atgcagctac ttactatgga
     2461 aatggtcttt attgtaacaa agaaaaatgt tgggtagatt ggaatcaagc taaaggagaa
     2521 attggaaaaa ttattgttaa tggttgggtt aatcatggtc catgggcacc tagaaggtag
     2581 tggtagggag gttattataa tggattttac taaagaagaa aaacttttaa atgcaattag
     2641 taaagtatac aatgaagcaa ctatagatga ctatcctgac ttaaaagaaa agctctttct
     2701 ttattctaaa gaaatcagtg agggaaaaag tgttggtgaa gttagtatga aattaagtag
     2761 ttttcttgga agatatattt taaaacataa atttggatta cctaaatctt taatagaatt
     2821 acaagaaatt gttagtaagg aatctcaagt atatagagga tgggcttcta ttggtatttg
     2881 gagttaattc tttggaataa aatgaaaatg ggactgaaga atcaattctg attcatcagt
     2941 cccataaatt atagagccga aaaattatca tatttataga tttattaata gtaaatggca
     3001 taagaatctt tgaacaacga aaaaaatgta gctctaccta attattgatt tgcaacaatt
     3061 tcaccgaagg tgaaacaagc gaaactttac aaaaagtggc tagcatttgc tagtcttttt
     3121 tgtattgtgg agagtggggg ggagggggat tcaaggggga gcttgcgccc ctttgacaag
     3181 cggttatttg caccaaatac gtaggtattt ggctagcaaa tatagagctt gccaaaccct
     3241 ttagtgagct ttagtgagct ttacttattg taccttttta ggtacaatgg tattgcgaac
     3301 gatacgtccg taggacgtac tgaaagggtg ggacttatga gcgaacaaaa tcaatatttg
     3361 gctagcaatc attctaaaaa atatacctat cgatccgagc caaaacaaat cagttttcga
     3421 gtgagcgaat ccgaatttgc aaagctgaag cagtcagctg aagctttgca aatgagtgtg
     3481 ccggctttcg tgaaagccaa ggcacaaaac gcgcgtctgg tgacaccgaa agtggcgcca
     3541 gacattgctc aggcaatcgc gcgcgattta gccaaagctg gcgggaatat caatcaaatt
     3601 gccaagtggt gcaacacaca ccaacacgac gttgatcctg gcgacgccca acgcttatcc
     3661 gaaaacctaa aaatcatgca aaaggagcta caaaagatat ggcaacagtt aaagtaagcc
     3721 gaaccacttc ttgtagccga gcgatcaatt acgccgaacc acgagcaacc attaaaacag
     3781 gaataaactg tgacgtcgat tatgccaaaa gtgaaatgaa acaaattcgc atgctgtatg
     3841 gaaaagacga ccgtgtacag gcacacttat tgattcaatc ttttcgacca ggagaaatta
     3901 ccgctgaaaa agccaatcaa ctaggggcag agtatgcaaa aaaaatagcc cccgatcacc
     3961 aaatagctat ttacacacat acagacaaag accatattca taatcacatt gtcattaact
     4021 ccgttaatct ggagactgga aaaaaatttc aagctcatgg tcaagcattt ctaaacaaat
     4081 gttatgacct aaatgacgag atttgtcttg cacataactt accaatcact gagcgaggaa
     4141 agaaaccaga aaaacgaacc atgtctgaaa taaaattaaa agaaaaaaat gaacctgttt
     4201 ggaaagacga aattcggatt gcgattgatc aaacaatgaa aaacaaaaaa accagaacct
     4261 atgaccaatt ttgtaattcc ctcaaaacat tggggattca ttgcttcaat cgcgggaaaa
     4321 atttcactta cgaattgatc cacaaaaaga aaaaagtacg atccaacaga ctaggaaagg
     4381 actacgaaaa ggagacgatt ttacatgagc tggacagacg agaacgaacc tataaccaac
     4441 agcgaaccaa cgagctacga agagctcgag ctagcattcg cgaaactgca gaagaagtac
     4501 gaagagaaca acgaactctt acgcctgaac aaccggaaat tagaccggct cgaagaaacc
     4561 atgaacaaca cgttgaaaga ggaacagacc accaacaaga attatcgctc taaaacgtta
     4621 aaagacatag aaaacgaaat aaagaaacaa cgtgcttttc tcgttcctta tacgcaagaa
     4681 aggatacaaa ctacgattga tttacaagtt aaaaaactcc atcaagagct attagaccag
     4741 cgaaataagg aacagaaaaa ggtgcttatt caacgatcat tggattttct tgccccctta
     4801 tgttgcttag tcctgacact gttcgcattt tggttagtat ggggaggcta aaatggcatt
     4861 ttatttaccc tatctactca tttttgttag tatttcagga agtatttggc tcatctataa
     4921 aatttttcaa acaagatatt cattaaaagg ctctaaaatt cgatttaagc gatttttctt
     4981 tcttggctgt atattttcct tgataatcgt ttcaagcggc ttattcggcg ttttagaggg
     5041 aaataagcgc gtttctagaa gtattttatt aggaaatgtc actcaaaagt atgaatcagc
     5101 gcgtgataaa aagaaaaaag agcaagtatt agcacaaaaa atagaaaaat ttaccgcttg
     5161 ttatgaggac atgaatgata tttttgtgaa gcaagaaaag cgtttgacgg ataaaaatat
     5221 ggaaacactc actcgacttt atcggaattt gccagaagaa cagcaaaaag agtaccaaga
     5281 aaaatatgaa caagtaaaaa aagacgtgca atatgtgaaa gatacgaaag tggaagaagc
     5341 ttgtagtgat ttatttggag atacaattcc tttttcaact agcgaacaag aacgaaaaga
     5401 acgacaacaa tcagtcacat atgaacgcta tgaaatcttg cttcaacaag caattaacat
     5461 acaaaatctg actaaaaaag aaacagcttt aaattattta aaaagcgtca aggaatggtt
     5521 agatcagcaa cagcaaaatt gaatttgatt gaaattcatg ttaaactaaa catgcaaatg
     5581 ttcaaacatt agatacacga aagccccaga gaggtcggat tctctggggc tttttttagg
     5641 ttgatgtcgc ctttactgat tttacttctt gtttcggtta ttcaaccaat aactgaatac
     5701 agagatacaa actcctacaa gaagggggca aataaacagt tcaaacatca gatacacctc
     5761 cttccagtcg caagactgtc ggataggcga caagttatta taccctacaa aattaaatct
     5821 gtgtggcaat tttaagtatc tcttatttcc gggttgttag ggcttgccct gaccgcctgt
     5881 agggcgcttt aaatgccaga taaaggtttt tatactaaga ctgtcttaaa acggcttaga
     5941 caagctctta gagcctcaac cctccttttt gaacaatggt tttagcaaag gagctggagg
     6001 cgactgcgca ggtataatgt gagagcgtag cgatcacacc tttttggcga ccgtagggag
     6061 cgaggttttg aattagcagt ttagaaaagt tcgcgaacct gtttaaagaa aaaataattg
     6121 tttttttagg tgggaaattt tgtctccctc ttttataatc tttttttaaa cctcttttta
     6181 aacctcttta ccgtcggctg tgtccttact cccccaaggg atacaaaatt ttataggcat
     6241 gaaattatct gtttataggc atgaaattat ctgtttatag gcatgaaatt atctgtttat
     6301 aggcatgaaa ttatctgttt taggtattgt ttttagacat aatatgtcct aaaatgatgt
     6361 caataaaatc atttagactg gagtaacaac taaatggcaa atgaaatcgt aaagtatgaa
     6421 ccagaattaa ataccattcc tttaagaaaa tttaccccaa tagaaatgaa cttgtttttt
     6481 tctattgtct ctagaatgcg cgataaaggt aatcaaaaaa tacgctttta tttcagccaa
     6541 cttaaagatt taagtgcgta taagcagact gcaggagaag tctttataaa agatttggca
     6601 agaacatacg atcatttgat ggatttacgt ttcggaagaa aaagcaatgg tggattaaca
     6661 atagaacgat ttacaatgtt tactgatttt gaaattcatg gagaagtcga taacccttat
     6721 gtagatataa aagtccacga aaaagctttg cctttactta ataatctaga aagctgggta
     6781 cgtttctctt taacagaatt tcgagattta aatagcagtt atgctaaaac aatgtttaga
     6841 ttgctaaaac aataccgaac tcaaggatgg gctgaatttt ctaaggaaga ttttttagag
     6901 ctattagata ttcctaaaag ctatagacaa acaaatataa atcagtttgt actcaaacca
     6961 ataaaagaag aactaactcc actatttaaa ggattaacta ttcgtaaaaa atatggtaaa
     7021 ggtcgaggta aacctgttat tggttatcgt tttacttgga aagctgaaat caaccatgct
     7081 gacgattttt caaaagggaa gcaagaagat ttacgtataa aattatttaa tattgaacac
     7141 aatggagaat taacacaaaa agaaaaatgg cgtgctaaag atcgaatact aaatcttccg
     7201 ttaggtactc atgaagctga ttttaaaaaa caacaacaaa ccgaaaaaga agaagcggaa
     7261 aaacaatcaa tctcaaatga gcttaaacaa gatttattag aaaacttaca aaacttattc
     7321 gattgaagca taaggagtat ttatgataga taaaacgatc aaagaactcg cggaagaatt
     7381 tcatgtttca aaacaagcaa ttaggaaaag gctatcagct gattttagag aaaactatgt
     7441 gcaaactgtt actaggaacg gagtgaaaac cttagttgtc agctacaaag gatatttgct
     7501 tttaaaacaa cattttttag gtagtaacac cactggtaac caagtagaaa ccgttgctag
     7561 taacgatgaa aactcgatta ttgttttttt acatgaacag ctccaagaaa aagatactca
     7621 aataaaacaa atgcaaaagt tactcgacca gcaacaacaa ctcaccttgc aggcaaatca
     7681 acagatcgaa aaactgcaag aacagttaca attagcttat acggaagaac ctgaagaaga
     7741 ggaattaact tctgtcaata aagaaaacaa caatgcaata acaacagaaa aaaagtggtg
     7801 gaaattttgg taacaattac caactttcca taaagaagaa atcaatttct atagactcta
     7861 tctttctaag aataaaaaat atgtttaggt gatcaaatga ctataagtaa agtaatcaaa
     7921 caaaaaagaa tagaaaaaca actaactcaa gaagatttag ctgaaatgct tttagtatct
     7981 aaaaaaacca tttctaattg ggaaaatggt cgaacaatac cagatacaga aaatttaatt
     8041 cagtttgcta agttatttga tttatcacta gacaatattt tgttaggaga agaaaaaatt
     8101 atggtaaaaa atcatacaaa aacactaata ctattatttc attttgtaat ttttttaagt
     8161 ttagttttca ccttaattca gtccggattc ttttatttta gccattcaat tgccacttgg
     8221 ttattaatat tttttctaag tttactatta ataattaata ctttaattat tatctttaat
     8281 aaacatagaa acttatttct tcacagcata tttccaattg ttttattaat ttttctatac
     8341 tttatataaa aagatagaac tatttagtaa gataaaaaag tagctaattg taattttcgt
     8401 ctaaaactca aaactagtaa aaataacttt attgtgttat ttttatttat aaattatgaa
     8461 aaaggacctt tcgaaatgaa aaataataga atctacaaaa atcagttgaa ttatgggctt
     8521 ttattgccag tttttctgct atgtatcatt ggattacttt ctttatatgt tgctttatat
     8581 cacgactctt acactaattc aaaaatcaca aaagaattaa ttaaacaagt attgtggtat
     8641 agtattgggt tcacttcagc aataactatt tattttttta atcctaaaat tttgtggaaa
     8701 ttaactccta tattttacgg attatgcatc ataatgttat tacttctctt gaaattctat
     8761 aatccacaat tagcagtctt aactggagca aaaaattggt tttatattgc tggtttttcg
     8821 tttcaaccta ctgagttagt caaaatagga tacaccctta tgctagctaa aataaccgtc
     8881 aattatcagc aaaaatctat tactagtaat acgaaagatg attggattta tttacttaaa
     8941 acttttattg ctactcttcc aataggaata ttattatttt ttcagaacga tctaggaaca
     9001 atgttagtct tcattgttat ttatattttt attttgttta cgtctaacat aaatataaaa
     9061 ataattgccc caataatcgc cattggtgtt gttttatcct taatattttt atatttggtt
     9121 atatcagata caggaagaga tttcttatta aaaataggat ttcacgacta tcagtttaaa
     9181 agaatagact catggttgaa tccattttta gatccaaatg gatctagcta tcagttagca
     9241 aatagtttaa ttgctattgg ctctggcgga cttttaggta ctggttt
//
LOCUS       DAMEEU010000096         9119 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.098, whole genome shotgun sequence.
ACCESSION   DAMEEU010000096 DAMEEU010000000
VERSION     DAMEEU010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9119
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.098"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..408)
                     /locus_tag="PB779_002518"
     CDS             complement(<1..408)
                     /locus_tag="PB779_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740011.1"
                     /translation="MEFTIGGVTLNRIKFYIDSSKKTIKQISTETGINYTTLTNYYRG
                     ERNPRNTETWNILADYFHVPVSYLMGLDETNSIEQPNLDRIKTARLEKKDKIVKNIAS
                     LDSDYFTELSNLYFSMTSLLEVKLQEDDSDFLFL"
     gene            531..731
                     /locus_tag="PB779_002519"
     CDS             531..731
                     /locus_tag="PB779_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740012.1"
                     /translation="MITLNDQFIRSLRRHRADLILTKNDAAKLIGINRKTYVKIENGS
                     KESIRASTYQKLVNWLLNDLKI"
     gene            743..1069
                     /locus_tag="PB779_002520"
     CDS             743..1069
                     /locus_tag="PB779_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740013.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDTGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            1222..2274
                     /locus_tag="PB779_002521"
     CDS             1222..2274
                     /locus_tag="PB779_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDE0740014.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            2350..2568
                     /locus_tag="PB779_002522"
     CDS             2350..2568
                     /locus_tag="PB779_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740015.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            2555..5233
                     /locus_tag="PB779_002523"
     CDS             2555..5233
                     /locus_tag="PB779_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740016.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKSVDVRENVQGSSASQPKTVDVRENVQSSTSSQGF
                     KTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKFDSNHETVIIDSEIRENDKGSKSR
                     RRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSCN"
     gene            5224..5421
                     /locus_tag="PB779_002524"
     CDS             5224..5421
                     /locus_tag="PB779_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740017.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            5425..6036
                     /gene="mobC"
                     /locus_tag="PB779_002525"
     CDS             5425..6036
                     /gene="mobC"
                     /locus_tag="PB779_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDE0740018.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            6021..7412
                     /locus_tag="PB779_002526"
     CDS             6021..7412
                     /locus_tag="PB779_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDE0740019.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            7628..7942
                     /locus_tag="PB779_002527"
     CDS             7628..7942
                     /locus_tag="PB779_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740020.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            7935..8429
                     /locus_tag="PB779_002528"
     CDS             7935..8429
                     /locus_tag="PB779_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740021.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            8497..8811
                     /locus_tag="PB779_002529"
     CDS             8497..8811
                     /locus_tag="PB779_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740022.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            8910..>9119
                     /locus_tag="PB779_002530"
     CDS             8910..>9119
                     /locus_tag="PB779_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HDE0740023.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         3538 a         1202 c         1711 g         2668 t
ORIGIN      
        1 taaaaaaaga aagtcggagt catcttcttg aagtttgact tcaagtaaag aagtcatgga
       61 aaagtataga ttagataatt cagtaaaata atctgagtca agactggcaa tattcttgac
      121 tattttgtcc tttttttcta aacgagcagt ttttattcta tcaagattag gttgttctat
      181 ggaatttgtt tcgtctaatc ccatcaaata acttacagga acatggaaat aatcagcaag
      241 gatattccat gtttcagtat ttctaggatt tcgctcacca cggtaatagt tcgtaagagt
      301 tgtatagtta ataccagttt ctgtactaat ttgtttaatg gtctttttac tggaatcaat
      361 ataaaatttt attctattca aagtaacgcc ccctatagta aattccaaac tattatagca
      421 tgaaaaccac aaattgagta atattttaat tgatattact cgttttgtgg tttaaaatgt
      481 gcttattaag ataaaaacca caaagtgaat aatttgaaag gaggcgctga atgataactc
      541 ttaatgatca attcattaga agcttaagaa gacatagagc cgatcttata cttactaaaa
      601 acgatgcagc aaaattgata ggtataaatc ggaaaacata tgtcaaaatc gaaaatggga
      661 gcaaagaaag tattagagca tctacttatc aaaagttggt aaattggtta cttaatgatt
      721 tgaaaatcta aataaataca acttggcgag ttggctgatt gaagaaatag aaaatgagag
      781 gagaaaaata atggatgcag gaattacagt aatgttagat aaacaacaaa cgaatcaatt
      841 gaaaaattat gtttttgaaa tgacaaaaga ggctattgat caagcaagaa ttgataccgg
      901 attagaaaga ccatttctaa aaggaaaaga gatggctaaa tatttgaatg tatcatatac
      961 aacttttttg aaatttaaaa gaatgggatt gccagttatt ttattagaaa aaatggagtt
     1021 gttttcaaaa gaagaatgca aaaaatggat attgagtcat caaatttaaa aaacacctcg
     1081 ttttttaaat ttgatgaagt agaaaaaatt aaaaagagtg ttcccgtcag tttgcagatc
     1141 gggggaacac tcaataataa agttctgaga aaactttatt tgaatctatt atagcaaata
     1201 aaatcagaag caggtgtgac aatgaatgaa aaagaagttg aaagcttagt tgaaaagcaa
     1261 ggctattcta attctgatat atatgcagaa ttatactatc aatatcctat ttttttaaac
     1321 gtaaatgaaa aatataagaa aatgaaacta agttctaagt tagtttatat gttactaaaa
     1381 gatagaaata gactttcatt gaaaaataac ttgtatgatg agaatcaaaa aatttttttg
     1441 atatttgaaa tcaaaaatct cgtagaaatt tcgggaatgt caaaaaatac aatcttatca
     1501 gcactagatg aacttcaaaa agttaaactt cttgtgaaaa gaaaaaatgg cttcaataaa
     1561 agtaaaatgc aaatgttccc aaatttttat tatttgttaa agcctgttct gtgcaaagat
     1621 gatgtttata aaattaataa gataacccat caagaaaata gacaaaaaaa cttgatagtt
     1681 caaaatttga actatggaac aaatcaatat tctgttgata gttcaaaatt tgaactatgc
     1741 gacacatcaa tgaaaacaag agacaaaaac aattttgctg atagttcaaa aaatgaacta
     1801 gaattatata agtcttataa agatagtaaa gatattaaag aatcacataa tgatgatctt
     1861 cttgaatcac tttcaactaa aaataataaa ttagatgaag aattgatcga aacatttatt
     1921 gaagaaaatc ttcttaaaca aatatgggga gaaagtattg tgaattgctt aaaactggct
     1981 agcaatagtg attatcgtca attcgacaac tggtacaaaa aattcaaata tgcgattaga
     2041 tctgctgaaa aagaacaaaa aattcaactg aaaattatct atgaaatttg taataacaag
     2101 tattttgtag atcatgttag agaacagcta tcaatgactt tacgtgactt gatacgaaga
     2161 gcaaaaacag atcatcgtat caaacaaaaa gacgattata tctttgcttc tctaaaaaat
     2221 aaagcgttag aactaattga attgcaaatc agcgaaggaa tagataagca ataagaatag
     2281 aattgagtca aatgaaatgg aggggtatct ccacttcatt tgagaacttt gaatatagga
     2341 ggggttattt tgattaaaaa tcgtttaata gatcaagttt ggtgtctaga tcaaaataca
     2401 gatagtctcg aattaatcga gactatttgc ttcaacacta tagttctcga tttaagagct
     2461 gaaaatgata attgtgtaac tcatgtcata attaatcaaa aaatggctca gaagctctct
     2521 gagagcctca gaaaatgggc taagggaggt aacgatgaaa ataattgaaa aaaagattgc
     2581 caataaaaaa ataaattggt tggttgttaa ttttcttgtt ctgatagcta tgattatttt
     2641 tacaagtaat attgctcatg cgagtatttt caattggttt gatgacacaa aaagtcaaac
     2701 agagtttttg aataattctc tttatagacc ttacctaaaa aagtacaatg gagatttcct
     2761 tagtcagttc gggatttggc tcggatgggc tgtggtaaaa ggcatgttta ctgtgacaga
     2821 ttcgattcaa aatatgattc cagatgtgct ggatttgttc aatttcattg aaagtacagg
     2881 gctaaataat gtttatcaat cagccgtaaa tacaattgtc attggattaa tgatcctttc
     2941 attgatgttt gttggttaca aaatgattac tggaaaagga acagtggatt taaaatcggt
     3001 tggaatgaac gtagtgatgt ctatagcatt aatactttta atgccaacca tgatttctag
     3061 tggtattcaa tttgctaaaa cattttataa ggactctact acgattacaa attcagatga
     3121 cggagtcgct tggtcattga taaaacaagg agtaacagat ttagcatata ttaataaaac
     3181 agatcagtac tcaagcattg ataaaacgga ggatcgaaat aatttaacac gaaaaaattt
     3241 tcaacagacg gatctcacac aagtgttaac ggataaagtg attgataaat tggaaaaaga
     3301 aaatccaatt gcggacaatc ttcgttatga attagttgaa aattctaata atgaatttgt
     3361 tgctacaaag ttttctgaca acttcttatc aacattttct gatagcttga aatcaggcta
     3421 ttaccgatac caagcaaatc tatgggggat ttcaattggg ttgacagcgt tagcaatcgc
     3481 ctatgtgttc agcgcgtttg tgatcattac agcaatacta gaacttgcat ttaaacgtgt
     3541 gttaggtgtt cttgtttttg caacagatat tgagacagga cagcgttcaa aagttgttct
     3601 atcagatatt ctacaatgtt acttaactgt tgggtttcaa ggatttgggt tatcaatgtt
     3661 tgctatgttt atcaattttc tgaactcagg acaaggtatc tcaacaaata tttttataaa
     3721 aacaattgct tatatctgtg ccgtttttgt tttaatcaaa ggcagtggaa cagtcatgag
     3781 atactttggt gttgatattg gactcaaaga aggctatggg caacttgctt ctgcttttgg
     3841 aatgggcgca atgctgttta gaaaaggatc aaatggattt aatcgtgcta aaggaagcgg
     3901 agaaggagaa gatcgaaaac cagaaaagaa tttcggcgaa actctatcaa aaaaagctgg
     3961 caaaactgga agagctttgg gatatgccca tgaacgtgga ttatccggtt tagcttcaga
     4021 tggagctaca atggctagtg aaagagcaac aaaaccattt aagagtatgc gtgatatagc
     4081 taatgatacc aagaataagt ttaaagaagg tttagatgat ggtacagtgt ccgctattaa
     4141 taaaaatagc aaacctatgt tagctaaaaa taaagaagat gaaactggaa aatatgctga
     4201 ttccgtgcca acacgtcttt cagatagaaa agatggtgct aaagttgaaa atgccgatag
     4261 aattatgtct agttctgaac gtatgcgtga agcaatgaaa aataatgctg aatcgaataa
     4321 taatcctgca agcgcaattc agcaaaaagt ccaacaagat attgaagaac gtaaaaatgc
     4381 tatgcacggt caagctaagt ctgctgaaga attaattaat cagaagcgtc atgaagcgaa
     4441 atacacgcct gaagcaatga atcgcgagga aataatgtta aggaaacgtg tagaagggcg
     4501 gacaggcgct aatattgacg gaaaagaagc gttgaccaaa gaaagaattc aagaagctaa
     4561 aaattcaaat acaggattag aaaaattagt caaagaaaat ccacaaaatt ctacaagtag
     4621 tcatggtggc cgatcagtag atgtccgaga aaatattcaa ggttcactga atggtcatgt
     4681 tggacggaat gttgatgtaa gagagaattt acaaagttct tcaaatgctc aaggtactaa
     4741 gacaattgat gttcgagaaa atctgcaaag tagcagtaca agtcaaccaa aaacagtaga
     4801 tgttcgagaa aatgtacaaa attctacaag tagtcaaggg tttaaatcag tggatgtccg
     4861 agagaatgtg caaggtagca gtgcaagtca accaaaaaca gtagatgtcc gagaaaatgt
     4921 acaaagttct acaagtagtc aaggattcaa aacagtagat gttcgggaga acattcaaaa
     4981 agatagtgga gaaatgaaag aaaaaacaca aaaaatcaat atcgttgaag acagaaagtc
     5041 agcgaaaaaa tttgattcaa atcatgaaac agtgattatt gatagtgaaa tccgtgaaaa
     5101 tgataaggga tcaaaatcaa gacgaagatt cacttatgaa gacaatgagt tattcagaga
     5161 tacacttaat gatcctaatc cacttttcga taatttatta agaaataaaa gggggggatt
     5221 gtcatgcaat taattctaaa gattagtacg catgatttct tagaacttga cgaattatgt
     5281 gaatcagtaa agaacgcaac aaatgaaaaa atcacggtca ctaattatat tgaactgatg
     5341 attcaagaag aattaaagat gaaaaatgaa atagagagca atttcaaatg ttgctctcta
     5401 gaaaaaaatg tgaggggata atcaatggat gataaacaaa aaatgtacga aaaaaatcgc
     5461 aaacatagtg aggccttaaa ttttcgtgtc gataaaaaga cttatcttga actgacattg
     5521 attgcaaaac aaaggggaat ttctagagca gacgtttgcc gtgagcggtt aaagggactc
     5581 aaatatgaac cgccgttgtt agctgaagat gatagggtag ttttaaccaa acagttaaat
     5641 caaattggta acaatttgaa tcaagcggta aaggcattaa atatcattgc taaatatttt
     5701 agagaagaat ctgaagataa aaaagaaaag agcctacatt ttagttttga tgctagccgt
     5761 tacaacattt ttaaagatga acttgcgaat agcatagcaa aaaagttgat gattagttat
     5821 ccagatgaca tttttttgga gtccaatcgg agtgccccct ctttttttaa attatcagaa
     5881 gtagaaaaag aatatttcga atattggata gaaaagcaaa ctagaccggg tacgaaagaa
     5941 gagtattccc aaaaagttga tcggaattta attcactcaa ttcagattat tgcaagttta
     6001 aaagatgagg tgaaacaact ttgggagcta ctataacatc gaaaggacgc aagaaaaatt
     6061 tatcctcgct attacaatat gcagctaatc cttcaaaaaa agaaaaatgt gttgcagtct
     6121 caggaataaa ttgtagtgat gatagtgagg aagcactgca agaaatgaat ttagtacgta
     6181 ccaagatgaa taaatctaaa gatatagcac aagcgtttca tgttattcat tcgtttgata
     6241 agagtacttc taaagagtta agtattgata aaatgcacga aatagctgtc gaatttgcag
     6301 agaaagcttt tccaaattcg caaatcattg ttgcaagtca caatgataaa gatcattttc
     6361 atagtcatct tgtcattaat aatattaaca tggaaacatg taaaaggttg cgtattgacc
     6421 ctaaagattt agaactaatg cgaaaaatta acgatcaagt cctcaatgaa catggtcttg
     6481 aatcagtgaa taatgagtac tatgaaaact tagaaaagag aaccaatctt tattcaaacg
     6541 atccttctaa gatgaaatat ggaaaaatta attatcaaga gtttgtgcaa aatgcgatcg
     6601 aagcaacgtt ggaaaaatgc gaagtgaatt cttttgaaga tttttcggat catttggcaa
     6661 aagaatataa cattgaagtt tatcaatttt caaaaacaaa taacaaactt ggctatgttc
     6721 tttacaaaca aggtgtaaat ttctatgagc gtagaggtga gttaattact ttaggaagag
     6781 ataaacaatc tagaaaagaa aaaagtcagt atgtcgaacg tacttttagt gcaagaaagt
     6841 tagggaaaag atattcattt gaatctgttt ctgaacaact tgaaaagaat ttagaagaat
     6901 cacatataaa aaattttttt aatatggaaa gagagcaagt tatgtcgcta attagtggag
     6961 taaattacaa aactggtgag ttaaatgtac cgtttgtgga attagattcc atcgcacaaa
     7021 agcaatttag cgaccgtgaa ggcgatgaaa aattcattaa atatgatgac ttcttgcgag
     7081 aggtagacaa gcattttgta aatacaatgt ctttagaaga tgatcaagaa tacacgatta
     7141 aacttcatac ggatgtgaat cctcaaactt tacgtagtgc gaaaagtaaa acaatttcta
     7201 ttaaaaagac tgatcagaaa gagttatttc taccggcaaa gggttttgaa aattgttctc
     7261 atacaccttc tgctaaacag attcactatc aaatcagtcg cataatgaat gacgatgtaa
     7321 aaatgtatcg tgctaaaaag gattatgaat tcacacaaca aatgattgaa aatcagcaaa
     7381 aaaggcaaca aaattttgaa atggaattct gaatgggctt gttagtggac tttccagttt
     7441 tttgcctatg aagagttgct tggaaagaag cagtttttag gacatacgcc agctacccat
     7501 ctacttgcca gtcaatccgc cccgctcacg ctaggctact ttctggcaag tcagatggcg
     7561 ggtaaatctc tgagggagca agctccctac agactccctc ccaaaaaaag aaaggtggaa
     7621 gaaaaaaatg aactatccat attttaaagt ctcggcttca gaagaaacta aagaaatatt
     7681 caacaatttt tacaaccaaa acaaaggaat ttttggttca aaggcaaata tgtttcgtgt
     7741 tatggtttca aatttaccag tgttagctag tccatcaaat aataaattta atgatcctga
     7801 aagcattaaa tttgaacaaa aaatttcaga actagaatca atgataagta atgaagtaat
     7861 tgaaaagctg gatgacattg atcaaaagtt atcgtattct ctaaaaaaca aatacaaaac
     7921 ggaggagaaa aaagatgttt aaagtttact tcccgtttca gtggctcgtt aaaggaattc
     7981 ttttagtgct actaggattg attctttttg gaagttatct aacaattaaa gccagacatt
     8041 ttccagaaga aaagccaata aaaattgtaa caaaagattt aaaaataggt gaaacttatc
     8101 aggcagatgg ggttgaacta acatttaaaa atattgaagt gaccgaaaaa agaaatgaat
     8161 ttgcacaaca tgatcgtgta ttacaagtga cctatacact tataaatgat acagaaaatc
     8221 cgatacgtcc acaacaatgg tcgattgaaa ataaggatgg tgaagaactt tatgagtatg
     8281 atatgatatt ggataatcca gagtatattg aaagtggcaa agaagaaaca gtaaattact
     8341 attatgaatt accgattgaa aggcaggact accaaatcgt agtacgtaga gagaatggtt
     8401 acatagttgg gttgccattt actttataag ttttattttg ttagtagttt ttaaggtaat
     8461 atcagttttg tgatttttga aaatggaact gggagaatgg ctgaggaaaa taaagttgtt
     8521 ccgtttgaaa cattagtgat aaataaggaa gagtttgagc aactttttct tgattttttt
     8581 attcaatatg acatgattta tgattttagt tcgtcactag atttatttga attagaagca
     8641 gaaataatag aaaacagtcg agagaagaat ggtaaaatca ttatttcagt agaaaaattc
     8701 aatgaattat tctcacaaac atttgaaata gatccagact attatcaacc acaagaagtt
     8761 tttcgagagt ttagaaataa gattattggt tttagtcaaa ctacaaaatg aaagcttaat
     8821 aaagcaagtg ttgatagaat tattcctcaa cgcttgcttt attttatggg cacttcataa
     8881 tagaggtata gagaagagag gtattcattt tggatactat tactccaaca aacttcaaag
     8941 aaaatatagg taaagtgttg caagaagtag ttcattcaaa ttctgaaata gaaattacta
     9001 gggattctaa aaatggattg aacgatggcg tcattatgat ttctaagaga aaatgggagt
     9061 tgttacaaga agaactttat ttacaacgaa cgggtacatg ggcttatgta tctgattta
//
LOCUS       DAMEEU010000097         9000 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.099, whole genome shotgun sequence.
ACCESSION   DAMEEU010000097 DAMEEU010000000
VERSION     DAMEEU010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 9000)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9000)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9000
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.099"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            12..509
                     /locus_tag="PB779_002531"
     CDS             12..509
                     /locus_tag="PB779_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740024.1"
                     /translation="MSYLIVCLIIIICLHHLFLSKTIPRYSKNKKAEKFCLLLNKFTL
                     IAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFLMSLKPPKSISLC
                     LVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYIGYFPNKNNNFYF
                     YRNKL"
     gene            complement(635..1312)
                     /gene="nth"
                     /locus_tag="PB779_002532"
     CDS             complement(635..1312)
                     /gene="nth"
                     /locus_tag="PB779_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HDE0740025.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(1319..2017)
                     /locus_tag="PB779_002533"
     CDS             complement(1319..2017)
                     /locus_tag="PB779_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HDE0740026.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            2285..3469
                     /locus_tag="PB779_002534"
     CDS             2285..3469
                     /locus_tag="PB779_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance MFS efflux pump"
                     /protein_id="HDE0740027.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGFAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            complement(3475..3918)
                     /locus_tag="PB779_002535"
     CDS             complement(3475..3918)
                     /locus_tag="PB779_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HDE0740028.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(4144..4431)
                     /locus_tag="PB779_002536"
     CDS             complement(4144..4431)
                     /locus_tag="PB779_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740029.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            complement(4602..5954)
                     /locus_tag="PB779_002537"
     CDS             complement(4602..5954)
                     /locus_tag="PB779_002537"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HDE0740030.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            complement(6227..6673)
                     /locus_tag="PB779_002538"
     CDS             complement(6227..6673)
                     /locus_tag="PB779_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HDE0740031.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            complement(6909..7835)
                     /gene="cysK"
                     /locus_tag="PB779_002539"
     CDS             complement(6909..7835)
                     /gene="cysK"
                     /locus_tag="PB779_002539"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HDE0740032.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            complement(7975..8862)
                     /locus_tag="PB779_002540"
     CDS             complement(7975..8862)
                     /locus_tag="PB779_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HDE0740033.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
BASE COUNT         2466 a         1826 c         1474 g         3234 t
ORIGIN      
        1 aaggcttcat tttgagttat ctgatagtat gcttaattat cataatttgt ctgcaccatc
       61 tttttttatc gaaaacaata cctcgttatt ccaagaataa aaaagctgaa aaattttgtt
      121 tattattaaa taaatttact ttaattgctc ctatccttgc atttattatt ttttctgtac
      181 ttttaagcac tactcttaaa ggaaaattta tggaaagaag ctctcatgca atgattctca
      241 cttttttatg gttgttgttc accagaatct atatttttct gatgagcctg aaaccgccca
      301 aatccattag tttatgttta gttataaatg gtattttttt attatcactt atcattttta
      361 ttacaccttt agatagatac gtcacttatt tatataatcc tttggaatac tggacttatt
      421 ttataggtat attggaaggc attattttct acatcgggta ttttcccaat aaaaataaca
      481 acttttattt ttatcgcaat aaattgtaat aagttaccat cctagctact gagtatgtac
      541 atttactttt tcatgcaaaa aagataaacg aaacagcttt tctccataat aacaagataa
      601 ttcatacatt tatttgcaat taaagaaacc acgtctacag gcgtggtttc ttttttagcg
      661 ccttttcttt tagacgcatc cgatttttcc catcttgaca tattgatagc aaaggacata
      721 cctcgcactt gggatttctt gccgtgcaat gatatctacc aaaaaaaatc agtgtatgat
      781 gtgtctttac ccataattct tgtggtactt tccgcatcag tgtttcttct acttccatga
      841 ccgtagcatc tagtttgcag atcctcaggc gttttgagac acgttccacg tgggtatcta
      901 ctgcgattgc tggtatcccg aatgcatccc ccaatacgac atttgctgtc tttctgccta
      961 caccaggaag agacatcaat tcttctcttg acgttggcac ttgcccatcg aaacgttcaa
     1021 tcagctgctg tgcacacgct ttgatgtttt ttgctttatt tcgatacaaa ccaatcgttt
     1081 ttattttaag aatgatttca tcgattgaag cttctgctaa cgcatcgggt gtcggaaaag
     1141 aggcaaacaa atctggcgtt gctttattca ctgatacatc tgtcgcctgg gcacttaaga
     1201 tcactgcaat caataactca aatggattat tgtgcttgag ttctccatgt gcttcgggaa
     1261 acattccata catcgtttct agagcttcca ttgttttttg tttgcttaac atattccgct
     1321 actcctccaa ccaatttttc agtgagactt tcggcaattc ttcttgttga gctgactgtt
     1381 ctacttctct ttgaagaagc tgctgttttc ttcgtttttg gtcttcttcc acttgttgtt
     1441 ttgtacgtag attttttctt tcccacgata gcaaaatgcg gtcaacgtaa ttaaaactat
     1501 aagcctgatt taatacggct tcccgcagtg ctagcttcaa aatttccggc tgataatggt
     1561 cttcttctag ccattgtccg atccgctgga actcgatcga agaaagcggg cgtccaaatt
     1621 cttgttcaaa taattgatac actgactgga tttctttttc ttgtgttttt tcttcgtatt
     1681 ttttttcttg tgtttttaaa tactcaccta atagatcata gatggggtaa agattatatc
     1741 gatctgcttt tttaccgttg acaatcgtcg tttctatctt gataaatcca tttgttacga
     1801 gacgatccag tatttgaaaa atctgatctt gtttgattcc catatccata gcaatcatct
     1861 gcaaatcagg gaaagtatct ccttcaagct gtgccatatg caactgtaga acaaataaaa
     1921 attcttcaga ttgtagaccg atcctatgat aatttttaag taaaagatta gatatgactg
     1981 tttgtccagc gcttaagtaa ttttctaaat tcaacatgat ttctcctccg ctcaatcaca
     2041 gtatacgtaa aaaaaacatg ggaagcaaga acaggtttct tttctattta cttcactgat
     2101 cggtcagatt tacaatgtcg tctacttgat ttttgtttgt tcatgttttt gatgcgtatc
     2161 ttcacttttc ggaataaata aattaagtag atttcgctgt tccttagaat gttgacaagg
     2221 aaacaaaatt actatacact atttttgttt ccaagttaac attattgcat aaaggagttt
     2281 ttacatgtac agtttcacaa ataaacattc taaagttttt ggatacgtct ctgtcttatt
     2341 cactggatta ggatttacta tcgtcagtcc tgtacttccg tttttaacgc tgccttattc
     2401 tcactccata catcagcaag ctttctatat cactttgctc atgtctgttt atgctctagc
     2461 tgccttctta tctgccccca ttctcggtag cttaagtgat cattttgggc gtcatccgat
     2521 ccttattatc agtttattag gatcaagtat cggatatttg ctttttggtt taggaaattc
     2581 gatatggatg ttgttccttg gtcgtatcat tgaaggattg acggcaggag aaatctccac
     2641 cttatatgct tactttgccg acatcacgga acctaatgaa agaaccaaag tttttggatg
     2701 gatgggtgct ttagtcggta taggaacaac gctgggtcct attatagggg gtctattagc
     2761 tgagttgggg aattctgttc ctatatttat tggagcactc tttactttct taaatgccgt
     2821 ttatggctac acatttatgc tagaaagcct tccaataaaa aaacgttcag tagatttaag
     2881 tttctcccat gtaagacctt ttcaccaatt acaacaatta ttcaagattt catccgttat
     2941 tcctttattg acagcaggtt ttgctgtttg gttggcagct ggctctcttc aatctatctt
     3001 ttctcaattt tcgattgacg cctttcagtg gaaggctggg ttggttggtt taagcttctc
     3061 tttgattgga atcttggata ctgtctcgca attgttcatt atgcctcgat tgctcaaaaa
     3121 attttcagaa cagcagatca caagaatagg gatgttcagt gaaatcctcg cctatctatt
     3181 catcacatta tctggaattc ttctactgcc gattttgttt ttatttggga ttatctgtta
     3241 tggtttcggt gattctattt ttactcctgt attcaatggc caactatcca attctgtctc
     3301 agataaccag caaggtcttg taatgggcgg tacccaaagt atacaatctc tatcgcgcgt
     3361 catcggcccg ctaatcgcag gacagcttta tgctgcagca ccatttcttc cgacggtatt
     3421 cggatttttg cttatgattt ttgcctatta tcactacaat aaaaaatagt agcttcattt
     3481 gctacttcgt ataaattctc tgtatcgacc gataaaacga aatactgtgt caaattcttc
     3541 ttttgacata ttttcaaata cagtagcatc tcgctgtacc catttttgat ggagttgctc
     3601 gtgtctattc cttatttttt gtccgattgg cgtcaattga aaatagattt cttttttatt
     3661 ctcttcgctt tgataagtgt ttatgatccc tctagctatc agtttttttg ttagcttact
     3721 gatggctcct ctagtcatgt aactagcatt cgctaatttt gtcacgttag gatcagggat
     3781 tttcccgata tgttcaatca cttctagttc atttagagta aatcctgcaa attctttttc
     3841 catttctggt ttattacgat gaataatctc attagctaaa tccagatatt cttctattag
     3901 cagttgtctt ttatccattt ctacaccttc tttttctttc attatattgt ttttttgttt
     3961 cctattcaac aaagataaaa atattttgta ggaaaaccca atctgaaacc aagaaaaaaa
     4021 ggggttgaca aagcttgtca taaccccttt ttctgattaa aagatagtaa agagacagtc
     4081 atcggtaatt gtgatgattt tttgtcatca cttaaggatg agcggccttt tcaaaaactg
     4141 tctttaaaga tcatcatcag tttctagcac atatggctga ccttcatatg tgtactctgt
     4201 attcaatgtg ccgtcatttt catctgagta gatgcgtcta ctgaaaggaa aacgatgaga
     4261 aacattatct ttggcgtcat ttgctggcat cgtgtaatat tcctcttgcg tttcattcaa
     4321 ctgagagagt acttgatctg ccaactcatc aatattgatc gttaatttct tcgaagcact
     4381 tttataatct tctaaaaatg catcttgttg gacaaaatat tctttattca tcttctttct
     4441 cacctttctt ttcaaaatca aataaagctg cttgttcttt tatgtaacag ctttatcttt
     4501 gctgcttatt gtgacaaaaa attcgaagaa agacaactaa ttgtactttt cacaaaaaaa
     4561 gacagagggt cgtgacaaaa ttgtgtcaca accctttttc tttattgtgc agtttcgatt
     4621 tcgcctagcg ctgcttgtgc aagtaggttc aagtaattcc atgggcggtc aaaatgtggt
     4681 tggaagaaga aatctgaaag tgcgagatct tctacagtca ttttattttg aacagctaaa
     4741 gacatggtat ttgctgattg tgtaatgtcg tatttggaca tgaactgagc acctacgata
     4801 cgattcgttc ctttttcata gactagctcc atcattactt tttcagtagt tggcatgaac
     4861 tctggacgat aattatcttc aaatacagtc gcttggactt ctagatcgtt caaagttgcg
     4921 ctttctttgg tcacacctgt cgaaccgatc gtccagccaa ataggtaaag tcctgaagtt
     4981 ccttgagtac cacgatacgc cattttatga tctgtcaagt tatttcccac aagcaaacct
     5041 tgacgaacgg catttgttgc caaaggaata tagttttgcg tgccacttgg attgtagttg
     5101 actactgcag agtctccagc tgcaaaaatg tctggattac ttgtctgcat gtattcattc
     5161 actttgattg ccccgtttgg cagtgtatct acttttcctt cgatcagttt tgtatttgga
     5221 cggaagccca cacataaaat gaccatatct gtatcaaatg tatctgttgg tgtagctact
     5281 tgtttcactt ttccttcttc atctgtgata aattcagtaa cattttcgcc tagcgcaaga
     5341 gtaacaccgc ggtctgtcaa ttctttttct aagatatctg tgaatggttt atctagatat
     5401 ttattcaaga tgcgatctaa tccatcaatc aatgtcactt gttttccaga ttcgacaaaa
     5461 gcttctacta attcaatacc gatatatcca ccaccaacaa ttactacacg ttttgcttct
     5521 ttcgcttgtg caataatttc atttgcttga ttgtagtttt tgcataggag tacatttttc
     5581 gcatcgattc cactaatcgg tgggataata ggccatgaac cagttgtcat cactaattta
     5641 tcataagaaa ccgtttctgt ttctcctgtt ttcagatctt ttgccgttac tgttttattt
     5701 tctgtatcga cgtctgttac atcgtgttcc attttaactg ttgctcctaa tgaagataat
     5761 tcttcaggat ttgagtagaa caagcctgct gggtccttta ctactccgcc gacataaagt
     5821 gcgataccgc aagataagaa agaaatattg tcatttcttt catatactgt cacttctgct
     5881 tctggatgat tttttaaaat actttttaca gctgcagtac ctgcatgagt acagccaatt
     5941 actactactt tcatttatgg tccctccgat taacattttg tccttcgaca aaactactat
     6001 aacagaaata aaacggatac aacagtttaa tgcttgtgaa ttcacaaagg tttgtttgta
     6061 gtttcattcc ttttcaagca taagaaccca atatctacaa gattcttatt ttaataatat
     6121 tcacttttat atctaagatt gtgaataaaa gacaaaaaaa taaaaaagct agcgtttttt
     6181 ttacacagct agcttttttt aggtataaca cttgtagaaa ctgtttttac atttgcgcct
     6241 tttttgctga ctctttacaa tccggacaga gtccatacaa ttccaaccga tgttcattaa
     6301 tctcaaaatc agtcagtctg cttgcagcca tttctatatc ttcaagccct gggtaatgaa
     6361 aatcaacaat cttaccgcag ttttcacaaa ttacatgata atgacgcttt gaactgaaat
     6421 caaatcggct agaagcatcg ccgtacttca tttcttgaac aaatccaatc gaagtaaata
     6481 agcgaaggtt attgtaaaca gtcgcaacac tcatatttgg aaaccgatgt tcaagtgctt
     6541 tataaatctc atcagccgtt ggatgggaat gatgttcaat caaatattct aaaaccgcgt
     6601 accgttgagg tgtgattcga atgttctctt tttttaactt ttcgataacc tcttcgacta
     6661 acttattttc catgtaaaca ccccacgttg ttattctcgt cttatcatac tatttttaca
     6721 ttttaaaatc cacttaacat gaaaagaaaa ttcaatttta ttgtatttta atgaaaaaag
     6781 acgtaaaaca gtcgcgttca ctattctacg tctctattca aataattttt ctcatcataa
     6841 atttttgtgt gttcttttca tctttaaaag ttttttacat aaacctatct ggagaaaaac
     6901 caagtgcctt atatctcttg gtaaagggct gtagataaat aacgttcacc attgtcggga
     6961 accacagcta ataccttctt gccttttcct aattcttttg cgacttttag cgcggcagca
     7021 attgcagcgc cagatgagat gcctactaaa atcccttctt ttcgcccaac ttctctagct
     7081 gtttccatcg cttcgtctcc actaatagaa aggactttat catacacaga agtatccagt
     7141 gttttaggaa caaaacctgt accgattcct tggattttgt gaggtcccgc ttctttccct
     7201 tctaaaatag cagattctgc tggttctacc ccgattaatt cgattttcgg atacacacgt
     7261 tttaattctc ggccagcgcc agtgatcgtt cctcctgtac cgatacctgc aacaaacgcg
     7321 tccaagccat ttactccaaa tgcttgatgt atctcaggac cagtcgtctt ctcatgcaca
     7381 agaggatttg cttcattttc aaattgtaat ggtaaaaagt agccgttttc ttttgccaaa
     7441 cgttctgctt ctctgattga tccagaaata ccatccgcac caggagtcaa aatcaactct
     7501 gcgccgtacc ctttcatcaa taaacgtctt tcgatactca tcgtctcagg catcacgatg
     7561 attactttat atccttttgc aactcctacc atcgacaatc cgattcctgt atttccagaa
     7621 gtaggttcaa tgatagtatc acctggtttc agtagaccat cgtgttctgc tttttctatc
     7681 atacttaaag caatacgatc ttttacactt cctcctggat taaaaaactc aagctttaca
     7741 aaaacatctg ctgaatcttc tggtacgatt ttatttaatt tgacgattgg cgttttgcca
     7801 atcaattcgg tgactgagtt atagatagct gtcatcttca attcctcctt gtctttgctc
     7861 ttcttactta tcataataca atctgttcat ttatggcgag tgattcgtct ttgactagca
     7921 aaaaaaagac aaagatatac catatatggt aatttctttg cctttttatc taaatcaaac
     7981 gtttagttct tgaccaacta ataaagaata actggacata gacatgccat ttttcgccat
     8041 tagatcatca acagacatgc caaatttttg tgcaatatcc catagcgtat cacctgacac
     8101 gactgtatat gtctgaccat tatttgtatt tacatctgtt gttgaagatg atgacgttga
     8161 agtcgtcgta gtagtcgttg ttgttgtact tgtggttgtt gtagccgaac ctgttgatgg
     8221 cgtatcaaaa cgggttaaat tataagtatt aatcaatgag ttcaatttgg ccccataatt
     8281 tggatcggta gcataacgac ctgtcaagta cgctgttgca tcataaaaac ttgttgtatt
     8341 gcttttccac acgccagcat aatgataatc gcccgtggaa aaactggttg aacgaagaac
     8401 attcgcatgg tcttggaagg attcccaata agaagaatat tttcggaatg gctcattcat
     8461 cgttacccat tgtccgttta catattcttt ggttgccata taaacgacct gtccgttata
     8521 gcttcctttc acaccgaata gattataatt tggcgcacta gctaatccgg aagtgccata
     8581 tgcactttcc aacaacgctt gagcgatcat gactgaagca tacaagtcat tacttgcagc
     8641 aacttctgac gcagaccagc cgatttgatc gataaacgct tgaggatcag cgactgtttg
     8701 agatccttgt tcatctgcat gaacatgttg cggtaccgct gtaaccatca tcggcccaac
     8761 taaaagactc gttccaatta aaggagcaat cgctttttta ttgatcacca tttttctttt
     8821 aggtctatgg tgccgggcac tgcgggtctt cagctcttgc attcaaattc ctcctcaaaa
     8881 taaaaaaact taataaaaag ttctcttctt aaaacaaact taattaatta aattatactt
     8941 ttaattccgc cgtttgtata attaagcgag acaaataaaa aagccattta tgttacactc
//
LOCUS       DAMEEU010000098         8817 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.100, whole genome shotgun sequence.
ACCESSION   DAMEEU010000098 DAMEEU010000000
VERSION     DAMEEU010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8817)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8817)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8817
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.100"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(942..1355)
                     /locus_tag="PB779_002541"
     CDS             complement(942..1355)
                     /locus_tag="PB779_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HDE0740034.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1811..2296)
                     /locus_tag="PB779_002542"
     CDS             complement(1811..2296)
                     /locus_tag="PB779_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740035.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2435..2650)
                     /locus_tag="PB779_002543"
     CDS             complement(2435..2650)
                     /locus_tag="PB779_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HDE0740036.1"
                     /translation="MKTLDAIALTLLIVGGLNWLLVGLFELDLVAMIAGGSTTIFAKI
                     IYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2874..3674
                     /locus_tag="PB779_002544"
     CDS             2874..3674
                     /locus_tag="PB779_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0740037.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3693..5561
                     /locus_tag="PB779_002545"
     CDS             3693..5561
                     /locus_tag="PB779_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HDE0740038.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNGVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5554..6045
                     /locus_tag="PB779_002546"
     CDS             5554..6045
                     /locus_tag="PB779_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HDE0740039.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6033..6587
                     /gene="srlA"
                     /locus_tag="PB779_002547"
     CDS             6033..6587
                     /gene="srlA"
                     /locus_tag="PB779_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HDE0740040.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6605..7600
                     /locus_tag="PB779_002548"
     CDS             6605..7600
                     /locus_tag="PB779_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HDE0740041.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVSTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
     gene            complement(7742..>8817)
                     /locus_tag="PB779_002549"
     CDS             complement(7742..>8817)
                     /locus_tag="PB779_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDE0740042.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT         3046 a         1425 c         1683 g         2663 t
ORIGIN      
        1 ttgttactat gaataacata ataagaaagt aaagtggatt gatttgagat ctttttatac
       61 ttcaaaaaag ataacaccca actttcaaaa atatgttttg gaagttggga caaacgagtt
      121 aatacatttt aatacattat tttttattca aaaaaaatag cacaatggca aagatcgtaa
      181 gagagatcat aagccccaat gaatgactaa aaagaaaagc agaatcacat gccatatcat
      241 cccatatttc ttcaagaaaa taaataagcg ggaaaaaggg aaggaatagt agaacatcga
      301 tccagcacca tttttttctt cttttgaaat aacataaaac aataaacatg aacgtgcagg
      361 gaagtaaaaa caaagcttta ctcataacta acaaaatacc agctcctttt atttttttct
      421 cccccacatt caaagagtaa caatggtatg tacttaataa tagaaaaatg gatcaacttg
      481 tatgaataac agctgaaaag atctgcacca aataaaaaac ttccagccaa aactgactgg
      541 aagtttattt ttttctgaaa tattctaaca caaatatgaa aaagatggcc gaagctaata
      601 agccgatttc gtagcaaaac aatgagatac cagagtcgta ataataaaat cctctaatct
      661 tatggataaa atagatcatc ggacaagcag ataagagtaa gtatttgtta ggccttttga
      721 ataagtaaaa gaaagcactg gtcattatga taaatggtat ccaaaacaaa agtttactta
      781 agacaatcaa atgatcaact cccatatttt ttaccaagag agatcataac atctttatcg
      841 taaaaacaaa atattttttt gctcattttg aaaatttaaa catactcgtt cttatccaaa
      901 tatataaaaa tcgcccctca ttcatcgaga ggcgataagt tctaatttaa ctcaattttt
      961 tttgtttctt ttggctgata agctgtttta ggtaatacca atttcagcac accgttttta
     1021 aaggttccag tgattttttc ttcatcaaca ttaggaagat agaatgaacg tttgtaagag
     1081 accgaatgtc tttctttccg tacatagttg ccatcttctt tatcttctgt atgggactca
     1141 tgattggcgg agatcgtcaa agtattatct gaatattcaa ctgtcgtgtc ttctttgtca
     1201 cagccaggca tatcagcagt tagtttgtat tctttttcat tttcgactaa atctactttt
     1261 ggataacttg aaacacctaa aaaatcattg aatgctggac taaacacgtc attgaaatca
     1321 gggaacatgt cgcgaatgct aggtacattt gccatttttg atcatccttt caataagtat
     1381 tttttattta tccctattta cgtaataact ctattttgaa aaaaatgcaa gtataatggt
     1441 tagctttgtg aatatttcat ctaatacgat acaaaggcta tctttctaat ttgaaaaagg
     1501 gatcattaaa ataataagaa gaaaatatgt caaaaggtaa aaaagtaaat tcttctatcc
     1561 aaatatagaa aaattgaatc tagaaaaccg cccgacaata aatttcatta actcagttga
     1621 ccgaaaatga agtagatacc aaaaatttat caagagagca agtagagaag tgagtatatt
     1681 cataagagaa atagctgtaa cgaattatta ggttaatgca aatgcttatt tatactccgt
     1741 ataactttct cagaaaaaat gataccaata atgacttgct agtactgtaa atccgtataa
     1801 tatcatctaa tcaaaatggt gttccatttg catctgtcat cgtaatcgat ccttcgggtg
     1861 acactcgata aaaaccaacg cttccagatc ctccttggga acggatttgt ttgctggaag
     1921 ctgtgaacaa ataatctcga tcaatttttt gataaaagct aataacaata tcgtcacttt
     1981 gtaattcgga acggtgggca ataagaaata gaagtgcttt gtcagagttt tctaatggaa
     2041 gagaaggtac agtgctttct tgcatttcag atgttgaaga aatgctaaac gactgaatac
     2101 ttgattggct atgttgcgaa tctacattac cagtagaagt attagtaatg gaagtagtag
     2161 aagtactttt agttgaacca acctcagttg ttgaaatggc tgctgaagat tctttaacag
     2221 aattctttgt tttatatcca caggcagaaa aaagtattac agttcccaac aagcctgcgt
     2281 aaatcccttt atgcatgata gctcctccta aaatagatta tctttattca gtatatcact
     2341 taaacaaaga aaagcagatg gtttaaaatg aaaaaacctt cccaataaag ggaaggttca
     2401 tgaagataat aactttttta ataattatag ctttctaata tctttcatca acttttctag
     2461 taatcattgg gaaaaatttc aagcagtaga tcgcacaaat acctacgacg atataaatga
     2521 tcttcgcaaa aatagttgtt gaaccaccag caatcatagc tactaaatca agttcgaaca
     2581 agcctaccaa cagccagttc aaccctccca caatcaataa agttaatgca atagcatcta
     2641 aagttttcat tagaattctc ctttcttaaa tgataaaaca attatatatc aaaaagagaa
     2701 acattgctta tataacgctc aggaatttta gcaatctatg caaaaagatg aaaatttttt
     2761 ttgctcttcc attagtacac attttttagc tgaagctgta aatttcatgt cttaattttt
     2821 tttagtgagc ttttatactg gatttgtaag aaaaaagaag gagaggatca catatgtcgg
     2881 attggttgga tattgcagga aaagtagtaa ttgtaactgg aggttcctca ggaattggaa
     2941 gaagtatcgt cgaaaatttg ttgaagcaga atgcacaagt agcgaatttt gatgtaactg
     3001 aatgccgtat acagcatgaa aacctactat ctttaaaagt cgatgtgtct tctaaaacgg
     3061 acatagaaga agggatatat aaagtaatga aacatttcaa gacgatcgat ggtctagtca
     3121 ataatgcagg aataaatatt ccttctcttc taatagatag aaatcatcca aaaagcaagt
     3181 atgaattatc agaacaagtt tttgataaga tgatcgctgt caatcaaaaa agtgtatatt
     3241 tgatgagcca agcagttgga agaatcttgg tgcaaaaggg atcaggagtg atcgtgaatc
     3301 tttcttctga atcaggattg gaaggatcag aaggacagag ctgttatgct gctacaaaag
     3361 cagcgatgaa cagttttact cgttcttggg caaaagagtt aggaaagagg aatgttcgtg
     3421 tggtaggtgt tgcaccaggg atactggaag aaaccggttt gagaacacaa gaatatgaag
     3481 aagctctttc ttatacgaga ggtataagcg tcgaacagct gagaaacggt tacagtcgaa
     3541 caagtacgat ccctctagga aggagtggta agctgcaaga agtggcggat ctagtctgct
     3601 attatctttc agaaagatca agttatatca ctggagtcac gactaatatt tcaggaggta
     3661 aaacaagagg ataaaggata ggggggacgc acgtgacgct agtaaacaga tggtaccaat
     3721 tattgaaatt actagtcact cacaagaaag tttcaatcca ggaagtgcaa aaagaaatca
     3781 aaaccagtaa tcaaaccata aaaaaagata ttggggagtt gaatgaagaa attgccggta
     3841 ttgcaaaaat catccaaaaa aacaaacatt ttgaacttga aatttatgat tttgattttt
     3901 ttgatgagat catgcaagga aaattgaaaa cagccagtga tttcaattcg gcatccaaaa
     3961 gaatcgctta tttactaaat aggctgatcg aaacagagga tttcttacgt atggatgatt
     4021 tgtctgaaga agtcggtgtc agcagaggaa cagtggtcaa ggatctaaag acattaaaag
     4081 agatgatcaa tgattttgat gtaaagatta caggcacacc aaataaagga ctaagaataa
     4141 taggagatga gctagaatta cgactacttt tattttattt tgtttctccc tacttttcag
     4201 agacgaaaac agaacagttt ctagaagaaa aacaagcaat caaacatttt cagaagaaga
     4261 cgaatgctag taaacaagaa atcacccttt taacgaaagt tatcggtatt tctttgaata
     4321 gaatctctag taactatctg ttgaagaagc ccatcaatcg ttacagtggg tgttttgaat
     4381 atatccaaga attcaatgaa ctgatcaatc agttggaaga aatctatgaa ctaactttga
     4441 gccaatatga aaaagatttt atcagttttc ctttgaacat catcaacaca agtataacga
     4501 tgataaggaa agctaactct gatttgcgct tatatttcga ccccatgatg atgcgtattc
     4561 gacgattaga tctcattgat ctggatgagt ccttcttata tcaagagatg aaacagcacc
     4621 tctctttatt gataaatcgg gtaatttttc gttatcgatt gactgattta ttttatggtg
     4681 agatagaaaa aaagtatcct ttttcttacc aaatcgctag cgaatgcata caagcattag
     4741 aagctatctt gcaacataag atctctaaag tagagatcag ctacctaacg ttgtatttgg
     4801 agttagcatt tcgatatcaa aaagagcatt tttcctctaa aaaagtagcc attgttcata
     4861 cgacaggaaa aggaacagca ttaatgatcc aaagacaaat caaaaggata ttggggaggg
     4921 atatacaaat aacacatgtt tcagaagaac aatatgaaaa agtagatcta aacaaatatt
     4981 tcgctgtttt tacaacgatt ccgttaaaaa atgtaaatga agagacaccg gtgatccatt
     5041 tgactaatct ttttgatgac tcttggttaa gggcacaatg gcaaaaagca aaaaaaaagc
     5101 gattagccgg gtttcattct actgtttttt tctatcaaat atggaaagaa aaaaagacgt
     5161 atcaagaata tttaaacaaa ttagtcgctc ctttgatcag aggctattat gtggatgaag
     5221 aatttgaaaa aaggatcttg aaaagagaat atcagcaaag cacatttgtt aacaaagaat
     5281 ttgcttttcc tcacacaacc aaccagctat ctcaacacat tgttttatca gtagggctaa
     5341 taactgatca aggtttagca gaaacaggag gaaatggagt tattttttta tttgccatac
     5401 ctgaagaaat gacggctgaa gttgagaatg aattatttga gctatacgat atcctatttg
     5461 aactcataaa aatgggaata gatgagttta ttgaattagc accgacacaa gaatcatttt
     5521 taaaactaat caaaagtaaa ggagagagac ttcatgaatg atatgtatct attcatagtt
     5581 ttcgcagctt cagcttatgt gctgcaagca gttatcagtt ggaagcaact aaagcatttc
     5641 aatcaaacat atagcgaact gcgaagaaaa ggaaaagtag cgattggtaa acgacctggg
     5701 aaaatccgtt caggcacgat tgttatgcta gctatagacg atcatgatca agttttagaa
     5761 gtcagaaaaa tgcaaggggt tacatctttg gcaaaatttc attcattacc tgtctatgcg
     5821 ggtgaagata tccattacat cgatcgttac catccctcag ttcgagcgga agatcgtttg
     5881 acacaagcag ctttagaaaa tgccagagaa gtatacttac gaatagaggc aggaaatgaa
     5941 aaaagtgaac aaccttcatt gccttttatt gctatgctca ataattttcg gatatggaaa
     6001 agtacgatca aagaaaaaag gagtgacaaa cgatggatat cataacaaaa tttgctgagg
     6061 gatttatgag gctgttccaa acaggtgcag aaacattcat aagctggatg acaggaatcg
     6121 taccagttgt cttgatgctg atggttgcaa tgaatacgct gattgctttt ttaggtgaag
     6181 accgagtaac gaaagtagcc aaattatcag cgaaaaatcc gcttactcgt taccttgtgt
     6241 taccgttctt atctgctttt atgttgggaa atcctatgtc atttacaatg gctcgtttcc
     6301 ttccagaata ctacaaacca agctattatg ctgctcaagc tcaattttgt catacgagca
     6361 atggtgtatt cccccatatt aatcctggag aattgtttgt atggatgggg attgctcaag
     6421 ggatcgaaac cttagggcta aattcgatgg agctggctat ccgatacttg cttgtgggac
     6481 tgctgatgaa ctttattggt ggttggataa ctgattttac tactggattt gtatgcagac
     6541 agcaaggaat cgttcttagc aaaaaagtag agctttcagt tgattagaga aaggagagtt
     6601 ttaaatgtat ggtgatatta agatcgtaag aggaaacggc gggtatggag gtcctttgat
     6661 tattaggccg acaaaagata aacacaagtt catctatgtc acaggtggag gtgagaggcc
     6721 aatgatcgta gataaaatag aagaactgac aggtatggag tctatcaatg ggttcaaaac
     6781 atcaatacct gatagtgaaa tcgcgcttgc aatcgttgac tgtggaggga ctcttagatg
     6841 tggaatttat cctaaaaaag ggataccaac catcaatatc gtttccacag gaaaaagtgg
     6901 cccattagca caatatatca ctgaagatat ttatgtttca gcagtagggt tagaacaaat
     6961 acagccacta atggaaactg atgataacaa agaaacagta aatactgcat ctccagataa
     7021 aaagtacaaa tatgatactt ctaaaaagat aaccgagcaa aaagcagagc agcaaaactg
     7081 gatagcaaaa attggaatgg gcgcgggaaa agtagttgct acattcaatc aatcagcaag
     7141 agaagcagta gatacgatga tccggacagt gatccctttt atggctttcg tttccctttt
     7201 gattggtgtg atacaaggtt ctgggatcgg taatgtattt gctaacatta tggcaccttt
     7261 agcaggaaat gcagttggat taacaatcat tggctttatt tgttcactgc catttttatc
     7321 tcctttgctt ggtccagggg cagttattag ccaagtgatt ggaacattga tcggtgtaga
     7381 gattgggaaa ggaaatattc ctccccaatt agcattaccg gcactatttg ctatcaatac
     7441 tcaaaatgca tgtgatttta ttccagtcgg tctaggtttg gaagaagcaa aagctgagac
     7501 agtagaagta ggtgtaccat cagttcttta ttcaagattt cttaacggca tcccacgagt
     7561 tatcattgct tgggtagcaa gttttggatt atatagctga gtttagtcta atggtgataa
     7621 gtcaagatga aatttaagat tttctttatt gagtaatatg ttttgaagcg cacgaaacta
     7681 gacccgatca aaatcaaatt tttttcgggt tgattcaagg atttgcgtca ataacggatt
     7741 gttatttctc tatcacactc cttggtggcg tatagagttg gtgtttacgt agtagcgtat
     7801 ccaccagacg cgtaaatttt cttgcggtta ggacgagtgc acgtttgtgt tgatgctttg
     7861 gaacctcctt atatttactt tgataaaaag ctttgtattc aggaagataa ttttttacag
     7921 agttggcagc ttcaactaag tagtatctaa aatatcgatt tccttgtttt gtcagaggtg
     7981 tattttgcga ctgatagttt ccagattggt tcactttcca acttaatcca gcgtattttg
     8041 ccaattttgt ctgatcttca aatctttcga tttgaccaat ttcagcgatt aaaccggcag
     8101 catagacttt accaacgcct ggaatactgg ttaagcattg atattctgga atgacaacaa
     8161 ttacttgttc gatggcttta tctaattctt tgatattttt ttcaagtgct cgtatttctc
     8221 gtacgagaac acttaaaaca acattaattg attcttgtgc aagagcacct aggcggtaac
     8281 tcatggtaat tgcacgttga attgctttag cgattttttc tggttgcttg aaacggcctt
     8341 ttcctttttc ttgaagtaaa tcacagaaag cttctaaagg aagctcagca agttcatcca
     8401 atgtgaaatc ttccgtcatg agtgaaatga gggttgcact aaaaagactc gtcgattcgt
     8461 ctcgcatttc tcgagcaagc gtattacatt tgtacgttag attttcaaga aaatgttgct
     8521 ttgtacgaat caattgctta ataagttgat agcgagtacg tgttaaacgc tgtaaggcca
     8581 tgtatttctc ttctttgata ggggaagttg tgaatcgttg aatacgcaag aaatcagcga
     8641 ttcttaatgc atcgtttcga tcagttttat tctcatcaaa catgcgacta aattgtttca
     8701 cccgaaaagg attttcaatc gttacaagtg tgttgagctt ctttagtttc tcatcttcat
     8761 gaaaaaacat ggaaggatgg aagctgtaca tggacgttga ctccatgcca atcacaa
//
LOCUS       DAMEEU010000099         8410 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.101, whole genome shotgun sequence.
ACCESSION   DAMEEU010000099 DAMEEU010000000
VERSION     DAMEEU010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8410)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8410)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8410
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.101"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            5..2377
                     /locus_tag="PB779_002550"
     CDS             5..2377
                     /locus_tag="PB779_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740043.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQKMTNGQ
                     PMNDKRNGRSWFNQQERIENKVQSLREEIKQQEEYVEKLERQEELKEMGYNKYGGLDM
                     TIDNIPRIKEEIERFEKGESAFSAATIRKYQRKLETLEQLKEKSEKGKENILPEVQAI
                     IDSGRVTQWKKNPTIYFLKGYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     RPTDSMKEKENDHFYRVEFNENDPEKGLKSYGGEIVTFELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQSVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTLETPENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2438..3898
                     /locus_tag="PB779_002551"
     CDS             2438..3898
                     /locus_tag="PB779_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HDE0740044.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDPKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYAEKEGLIAELKPKYERQNF
                     LVRDDRLDHAVAFLWKDPQTKETVGASYQGTFIDYERFGERGTYKHIDKNSTANHGFN
                     LKIGDPKQIKFFESSIDLLSYAALNRDQLNDTWLVSMEGLKHHVISHYFGEAVSELRK
                     KQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDPFTNQKVRCERGIANDWQVPKEYKII
                     YEEVAKEEKVTPEAIMAIHKTENNLQLTNQLVSAHKVNAFFGQQLSVNDSIEAINLKD
                     ICREVAKELKVCERVDGTYDFDRFYQEKGDINAQILFSYKAEQYYKGYKNHEHEFVPE
                     VKKDWNDQLKHEIQQQEIRKQKRAMLFQQGRQQERE"
     gene            3909..6113
                     /gene="topB"
                     /locus_tag="PB779_002552"
     CDS             3909..6113
                     /gene="topB"
                     /locus_tag="PB779_002552"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HDE0740045.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFPGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQVGADQGKTFKRLWINSLEKEAIYQGFQQLRDAKETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FKKEPYFEGKSEVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGMIRQVE
                     TEKKSAASPRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDTPYITEG
                     EYAYLLDHLDEYKHFLRAEEISTPIHTPNSRYVNNKKVQEHYAIIPTKTVMTEATYES
                     LTPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKAIGKVPIDLGWKKLFGK
                     ESDGKEKEEEPLLPKVTKGEMVTVDLQVLEKETKPPQPYTEGTLITAMKTAGKTVDSE
                     EAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGVLLCQAVEKEPLLT
                     SAEMTAKWESYLLKIGERKGTQTTFLANIQKFVSHLLEVVPGQIQSIDFGSTLQEVKA
                     ASEKQEAARHLGICPKCQEQEVLLYQKVAACTSEACDFKLWTTIAKKKLTATQLKEII
                     QNSRTSQPVKGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNFKKRTRRTTK"
     gene            6129..6278
                     /locus_tag="PB779_002553"
     CDS             6129..6278
                     /locus_tag="PB779_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740046.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKLRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            6353..6946
                     /locus_tag="PB779_002554"
     CDS             6353..6946
                     /locus_tag="PB779_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HDE0740047.1"
                     /translation="MQEKLKELLAIRDGNLSMKEARKLGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEIEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            6959..7858
                     /locus_tag="PB779_002555"
     CDS             6959..7858
                     /locus_tag="PB779_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HDE0740048.1"
                     /translation="MTPTQFAAKTRNLAKRTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTAQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIIGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            7861..8358
                     /gene="ssb"
                     /locus_tag="PB779_002556"
     CDS             7861..8358
                     /gene="ssb"
                     /locus_tag="PB779_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HDE0740049.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGNR
                     EADFINCVIWRKPAETMVTLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSSTSPSTTTFEQRDTATPNNNGLNALQNPFGNPFGGQSIDISD
                     DDLPF"
BASE COUNT         3201 a         1402 c         1793 g         2014 t
ORIGIN      
        1 gaacatggca gaagaaaaag aaccactaga caatagtcgt ttgggaaaat ccaaaagaaa
       61 actagtacga ttgcaaaatg aattaaacga acaaattgaa aagatgtttg aacaccaaaa
      121 aatgacgaac ggtcaaccaa tgaacgacaa gaggaatggc cgttcatggt ttaaccagca
      181 agaacgaatc gaaaataaag tccaaagtct gagagaagag atcaagcaac aagaagaata
      241 cgtggaaaag cttgaaagac aagaagagct aaaggaaatg ggctataaca agtacggcgg
      301 actggatatg acgatcgata atattccaag aatcaaagaa gaaatcgaac gctttgaaaa
      361 aggtgaatcg gctttttcag ccgccacgat ccgaaaatac caacggaagt tggaaacatt
      421 agaacagctg aaagaaaaat cagaaaaagg aaaagaaaat atcctccctg aagtacaagc
      481 gatcattgac agcggacgag tgacgcaatg gaaaaaaaat ccaaccattt attttttgaa
      541 aggctatcga aaagttgctt tagaactgaa tgaaaacggg ggatttgagg aatcaaaaaa
      601 ataccaagcc acgtcggaag aggaaaaagc agctgttcgt gaattacttg aagaggctag
      661 accaactgat tctatgaagg agaaagaaaa cgatcatttc tatcgagtag aattcaacga
      721 aaatgatcca gaaaaaggat tgaaaagtta tggtggggag atcgtaacat tcgaattgat
      781 cgatcaactc aaaacattgg ataaccaata cgccgcagaa gcaggttatt ataaattcta
      841 ttttgaggaa gtgaagaacg gagaagtagt cgatcagatc cgaatggatc taggggatgg
      901 cgtcaacagt aatcaaccaa tctatttaga gttagcaaaa ttgtgcgaac aagtacctga
      961 gaaggaacaa aaacaatcgg tcaaaaatga acctgtttcg aaagaacaaa tgcagtcgaa
     1021 agaaacaaaa acaaaacaaa agggctatca aaaacgaacg gcagaagaga ttaaacaaga
     1081 agttaaatcc ctttcgcaac aggcactgga tgcggtgaaa aagcataccc attctcctga
     1141 agacgtcaaa gaacttttga actttatgtc tcgttttcca gaacgatcct ttagaaatca
     1201 attattgatt gaggaacaat ttccaggtgc aacggcttgt ttaggtcgtg ccgcgttgaa
     1261 aaaagaagga atctatatca aaaaagggga acaagggaac aagatctttg tcagaaaaac
     1321 ggtcaaaggg ttttatgaga aaggacgtgg ctttgttcga gaaacagaag ctacaccaga
     1381 agataaaaaa cgaatcgaaa gtggtcaaat cgaagtgatc aaaaaacctt actatacgat
     1441 tgaaaaagtg tttgatatca cacaaacaca gttaaaacct gaagactatc cgaaaatctt
     1501 tccgaaccgt gtctttgatt ttcaattgga taaaaaagga cagtcagaac ttcaagctgg
     1561 gattcaagcg gtagccaaca atattggaat acaaattcga gatatgacag aaagtgaagt
     1621 ctatcaaaga gaattaggac aagcacgtgg ggcgtatgtt cgtaacgaat ttactggcga
     1681 agaagaaatc gtcatgaata ctcgaaatac tcctacgcag catttagcta caagtattca
     1741 tgaattagcc catgcaagaa tgcacaaatt ttcagaatta gataccgcaa ctaaagaatt
     1801 gcaggcagaa atgacttctt atattgtgtg caaacatttt ggaatggaca cgtcggagaa
     1861 agctattcct tatattgcag catggacgaa gaatggtcag acgttggatg ataaggaagc
     1921 tgcggaacgt gggaaaatca tgaatgatgt cagccgtgtc gcaaatgaat tcattcaaac
     1981 catttctaat gaaatcaatc aatacagaga aagagaacca gagatccaac cagcagaagt
     2041 gaagcaggag cataaaaata ctttagaaac gccagagaat aagaatattg tgcccgttgg
     2101 ttcactttgg atcgacaaga aagacgggaa agtaatggaa gaagatacgg gtcgaacgtt
     2161 acatttgaag gatgcggcgt ttattgaaga tccgcagcat aatcaagtaa ttttaaaagg
     2221 aaaaagttat ggaaaagaga tccaaacggc gttaccttca gaagaatttg cgctaggaaa
     2281 tccattccga ttttcacttg agacagtgtc agaagtggca aaacgaaaaa atgaaatcta
     2341 ttatgaacaa caattgtcac aaaaagaacg tgtataaaac aagtaaaaaa gactatctga
     2401 aaaacggata gtcttttttc ttttgggagg ttttaaaatg accgagaaaa aaatgagtct
     2461 tattgatcga tgtaaacaga tcgatatagt ggattttgct cgaaacaatg gaatggctgt
     2521 agtcaataaa ggacgagatt atcgcttaga agaccatgat tcatttgttt ttgatcgaag
     2581 aaaacaacgt ttttattgga acagtcaaaa tattagtggc gacattattg aattagctaa
     2641 actttttttc atagacaaag agatccaaga ccctaagcaa caatttaaag cagccactga
     2701 ttttattcta aagaatgaag acaaaacaga acgagtggaa aatcttcatt ttgaaacaga
     2761 aaagtacaaa gatcaccccg ttgattatca accactcaca gaaaaaggaa ggaattatct
     2821 gaaggaagaa cgaaaactac cagagtggct gattgattat gcagaaaaag aagggttgat
     2881 tgccgaacta aagccaaaat atgaacggca aaatttctta gttcgagacg atcgtttaga
     2941 tcatgcggtc gcctttttat ggaaagatcc acagacaaaa gagacagtag gggcgagtta
     3001 tcaaggaacg ttcattgatt atgaacgttt tggtgagaga ggcacatata agcatataga
     3061 taaaaattcg acagcgaatc atggctttaa cctaaagatc ggtgacccta agcagataaa
     3121 attttttgag agtagtattg atttacttag ctatgctgca ctgaatcgtg atcagttaaa
     3181 cgatacgtgg ttagtctcta tggaagggtt aaaacaccat gtgatcagtc attattttgg
     3241 tgaggcagta tctgaattga gaaagaaaca agcctttcct caatccatcg agatttgtgt
     3301 ggataatgac cgtgcaggac atattttcta cgaaaaagaa caattaatgg gcgcagtcga
     3361 tccatttacg aatcagaaag tacgttgtga acgaggaatc gctaatgatt ggcaagtgcc
     3421 aaaagaatac aaaatcattt atgaagaagt cgcaaaagaa gaaaaggtca caccagaagc
     3481 tattatggcc atacacaaga cagaaaacaa tctgcaatta acgaaccaac tggtttccgc
     3541 tcacaaagta aatgcgtttt ttggccagca gctttctgtt aacgattcaa tagaagccat
     3601 taatttgaaa gatatttgta gagaagtcgc aaaagaatta aaagtttgtg aacgcgtgga
     3661 tggtacgtac gattttgatc gtttttatca agaaaaaggg gatattaatg cgcagattct
     3721 tttctcttat aaagcagaac aatactacaa aggctataaa aatcatgaac atgaatttgt
     3781 acctgaagta aaaaaggact ggaacgatca attgaagcat gagatccagc aacaagaaat
     3841 cagaaagcaa aaacgtgcca tgttgtttca acaaggcaga caacaagaaa gggagtgaaa
     3901 tcgtcatgat gaaaaccgtt attttagcag aaaagccgtc acaagcgaaa gcttatgccg
     3961 atagcttctc taaagccact cgaaaagacg ggtattttga aatccaagat cgattgtttc
     4021 ctggtgaaac tgtgatcacg tatggttttg gtcatttagt cgaattagat tcgcccgata
     4081 tgtacgatga aaattggaaa caatggtcat tagaacattt gcctattttc cctacacatt
     4141 atcactatca tgttcctaaa gataagaaaa agcaattcaa ggtggtgaaa cagcaacttc
     4201 aatcggccga caccattatt attgcgacag atagcgatcg tgaaggggaa ctgatcgctt
     4261 ggacgatcat tcaacaagta ggcgccgatc aaggaaaaac ctttaaaaga ctttggatca
     4321 actccttaga aaaagaagcc atttatcagg gattccagca gttacgagac gcaaaagaga
     4381 cctatccaaa atttgaagaa gcacaagcac gtcagatcgc cgattggtta attgggatga
     4441 acggtagccc actgtatagt ttactcttgc agcaaaaagg cataccagga agcttttcct
     4501 taggcagagt ccaaacccca acgctttaca tgatttatca attgcaggaa aagattagaa
     4561 atttcaagaa agaaccttat tttgaaggaa aatccgaagt aatcgctcaa aatggcgcat
     4621 ttgatgcgaa gcttgatccg aatgaaaccc aagcgacgca agaagcattt gaagattatt
     4681 taaaagaaaa gggggttcaa ttgggaaaac agccaggcat gattcgccaa gttgaaaccg
     4741 agaaaaaaag cgcggcaagt ccacgtcttt tttctctatc cagccttcag tctaaaatga
     4801 atcagctcat gaaagctagt gccaaagaca ctttggaagc catgcaaggc ttgtatgaag
     4861 ggaaatatct aagctatccg cgaacggata ccccttacat tacggaaggg gaatatgcgt
     4921 atctgttgga tcacttagac gaatacaagc attttttgag ggctgaagaa atttcgactc
     4981 ctattcatac accgaatagt aggtacgtga acaacaagaa agtccaggaa cattacgcaa
     5041 tcattcctac aaaaacagtt atgacagaag cgacgtatga aagtctgaca cctttacaac
     5101 aagcgattta cgagcaagtt ttaaaaacga cagtggcgat gtttgcggaa aaatatacct
     5161 atgaagaaac aacgatcttg acgcaagtcc agcagcttca gttaaaggca atcggaaaag
     5221 taccgataga tctaggttgg aagaagttat ttggcaaaga gagcgacgga aaagagaagg
     5281 aagaagagcc gctacttcct aaagtgacaa aaggagaaat ggtgacggta gatctacaag
     5341 tccttgaaaa agaaaccaag ccaccacaac cttataccga aggtacgttg atcactgcga
     5401 tgaaaacagc tgggaaaacc gtggatagtg aagaagcgca atccatattg aaagaagtgg
     5461 aaggaatcgg tacagaagcg acacgggcga atattattga aaccttgaaa caaaaggaat
     5521 atatcaaggt agagaaaaat aagcttgtgg tgacgaataa aggggttttg ctttgccaag
     5581 ctgtggaaaa agagccgctg cttacgagtg ccgaaatgac cgccaaatgg gaaagctact
     5641 tgttaaagat tggagaacga aaaggaacac aaaccacttt tctagccaat atccaaaagt
     5701 ttgtctctca cttattggaa gtcgtcccag gacaaatcca atccattgat tttggatcga
     5761 cgttacaaga agtgaaagca gccagtgaaa agcaagaagc cgcgcgtcat ttaggaattt
     5821 gtccaaaatg ccaggaacaa gaagtcttac tctatcaaaa ggtggcagct tgtacgtctg
     5881 aagcctgtga ttttaaatta tggacaacga ttgccaaaaa gaaactcaca gcgacacagc
     5941 tgaaggagat tattcaaaat agccgaacaa gccaaccagt gaaagggtta aaaggtcaga
     6001 agggttcgtt tgaagcaacg attgttttaa aagaagactt cactacaggc tttgaatttt
     6061 ctgaaaagaa aaaaacgaac ttcaagaaaa gaacacgacg cacgacaaaa taatggaggg
     6121 ttaatcttat gcgtaataca acacacaaac aacaagaaat cgaaaatcaa aaagccaaaa
     6181 ttcgttcaga acaagagaaa ttacgtgcca gtaaaagaag acttcagcaa ttaaagaacc
     6241 agcaacggat tcaaaaagaa atcgaattag atcgatagac attaaccttg ttacaaatac
     6301 actatcatga tatatttaat gtagtgtatt tgtaacaaaa ggggggaagt aaatgcaaga
     6361 gaaactgaaa gaattgttgg ctattcgcga tggaaattta tctatgaagg aagccagaaa
     6421 attaggaatc gcagcaacca ctgtacaaag attggtgaat caaggaaaat tgatcaaagt
     6481 tgatcgtggt tattatgtag aggatggtca tggaatagat gatttatttt ggcttcagca
     6541 acgtttttcc aggggaatct tctctcatga aacgacttta gatatttacc agctttctac
     6601 gaatatgccg aaattcattc acttaacttt tccccatgga tataacgttg atcgttcaat
     6661 tacaaaagag cagcagttac aatttcattt cgtgaagaaa gaagtttatg aactaggaaa
     6721 agtagaggga acttcctttc aaggaaatcc tattactatg tatgataaag agcgtacact
     6781 ttgtgatatt tggaatccga gatatgaaat tgaatatgaa atgaaattag aagcattaaa
     6841 agagtacatg gaagacccat tgagagatcc aagtaaatta agagattaca tgacaaaact
     6901 acatgtagaa aaagaaatga aataccacat gcaaagctta tattgatgga ggaaaaagat
     6961 gacaccgaca caatttgcag caaaaacaag aaatttagca aagaggacag gattaaatgc
     7021 acagttagta caacggcatt ttatgatgga tcgtttaatt gaacaaattt ctgaatctaa
     7081 gtataaaaat gatttcattt tgaaaggtgg ctttttatta ggatcaaaat atggaatcga
     7141 tagaaggacg acaattgata tcgacacgac atttagaaat agcaaattaa ctgaagaaaa
     7201 attgaagagt atttttaatg atttaactag gaaacccacg aaagaaggta ttgttttctc
     7261 tattcaagga atgaaggaaa caagagaagc cgatttttat cctggatttc aaattaaatt
     7321 ggtggctaat ttagagaaag tacgtgtgcc atttaaaatg gacgtgacaa caggagattc
     7381 tatttatcct gaagtagata cacactatca ccaattaatg tttgaagata aaaaggtgga
     7441 gattccagct tatccaacag cacaaattat tgcagaaaag ctaagtgcta cgttcagctt
     7501 tggcacagat aattcgagag caaaagatta ctacgactta tttaccattc cgaaactaga
     7561 aaatatcgat acgaaagagt tatacaaaag tgttcgaaat acatttacaa aacgtgggga
     7621 tacaaaaccg ttgtcctttt attatgaaag agaaatggat aagatcatag gaaatgacta
     7681 tttggaaaag cagtgggaaa aatatcgctc agttaacacg tttgcgaatt ccatttcatt
     7741 tacagataca gtcaacgaaa ttgatcacct aatgaaaagt gtgatcaaaa ttgaaaatca
     7801 agaaagaaaa cggcagttta aaagatcaca acaaatgaat caagaaatgg agagataaag
     7861 atgatcaata atgtaacttt agtaggacgc ttaaccaaag atccagattt acgttatacc
     7921 gcgagtggta ctgcagtagc gacttttacc ctagctgtca accgaaattt cacgaatcaa
     7981 aacggcaatc gagaagctga ttttattaac tgtgtgattt ggcgcaaacc agcagaaaca
     8041 atggtgacat tagctaaaaa aggtagcttg attggtgtag ttgggcggat tcaaacgcgg
     8101 acttatgaca accagcaagg acaacgtgtg tatgtgacag aagttgtggc cgataatttc
     8161 caactattag aaagcaaagc agcgacagaa agccgtgcgc acgctgatca atcgtccacc
     8221 agtccaagca ccaccacttt tgaacaacgg gatacagcga cgcctaataa caatggattg
     8281 aacgctttac agaatccatt tgggaatcca tttggtggac aatcaatcga tattagcgat
     8341 gatgatctac cgttctaagt agcattttct attggttgca tttgctacgg tttatgttat
     8401 aatttagtca
//
LOCUS       DAMEEU010000100         8246 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.102, whole genome shotgun sequence.
ACCESSION   DAMEEU010000100 DAMEEU010000000
VERSION     DAMEEU010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.102"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(365..1156)
                     /gene="msrA"
                     /locus_tag="PB779_002557"
     CDS             complement(365..1156)
                     /gene="msrA"
                     /locus_tag="PB779_002557"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDE0740050.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1347..1982)
                     /locus_tag="PB779_002558"
     CDS             complement(1347..1982)
                     /locus_tag="PB779_002558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDE0740051.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYGLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2248..3300)
                     /locus_tag="PB779_002559"
     CDS             complement(2248..3300)
                     /locus_tag="PB779_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0740052.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3313..4251)
                     /locus_tag="PB779_002560"
     CDS             complement(3313..4251)
                     /locus_tag="PB779_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDE0740053.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4702..5352)
                     /locus_tag="PB779_002561"
     CDS             complement(4702..5352)
                     /locus_tag="PB779_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740054.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5452..5961)
                     /locus_tag="PB779_002562"
     CDS             complement(5452..5961)
                     /locus_tag="PB779_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HDE0740055.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6046..6525)
                     /gene="rlmH"
                     /locus_tag="PB779_002563"
     CDS             complement(6046..6525)
                     /gene="rlmH"
                     /locus_tag="PB779_002563"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HDE0740056.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            6953..8242
                     /locus_tag="PB779_002564"
     CDS             6953..8242
                     /locus_tag="PB779_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HDE0740057.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENVKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         2615 a         1675 c         1320 g         2636 t
ORIGIN      
        1 tagttattgt ttgcgctttt atacggaatt tagttcatca ttaatgtgga attcgattag
       61 gtgtctatta attatcaaga tgattctcta caaaattcca tagaaaaatc aagattctac
      121 aattcgaatt ctctttcaca tggaaataaa ggctagtaaa aaaacaggag ttgtgacaaa
      181 agacttgtca tacctcctgt ttccttgcga cttgaagctg aatgctttgc gccacaacct
      241 tttcctcggt gttctcaaag caactcctcg aaataattca taactgtcca aaaatatgaa
      301 aagctatttt tgtcagttgc tcattatttt gtcggagctg aacgctttgc gccacaacct
      361 tcctctatct atgtcgctga aaaaataaat gaagctgatg cgaatgcttg atctttttat
      421 atcttttagg ttgcttctga taaaattgtt gatgatgatt ttcagctggc caaaaagtct
      481 ttgcttggcg aatctctgta acgataggac ggctaaatcg gttagattga atcagttgtt
      541 ctcttgattt ttcagccaat tgcctttgct tttcattaac aacaaataga attgaacgat
      601 attgtttccc ccgatcttga aattgaccaa aggcatctgt agggtctgaa atttgccaat
      661 aaatctccaa cagctcttca taggttattt gacgtgtatc aaatatgatc tcaacagctt
      721 caacatgccc agtatatcca ccactgactt gatcgtaatt tggttttttg gtctctccac
      781 ctgtataacc agataacact gagattacac ctggttttgt ttcaaaaggc tcaaccatac
      841 accagaaaca gccaccggca aaaatcgccc gttcttggta taagggtgaa gttatcttat
      901 gtttggcata atcataagcc tttgcactcg ctgactcccc tgtgattctt aaataaaaat
      961 ccatcgcatc tggtgtcaaa ttatctcgta gtgctagcgg acgcaagttg acctctagtt
     1021 tttctatcac ctgctttatc gacatttttg ctaggtcttc ttttgcctct tcaaattgtg
     1081 ttctttccca ttctcttgta tttcgattta aaataatatt ataaaggtct atttccatct
     1141 gctccacatc taacatgaag tcaccctctt tcaagttttc ttcttattca ttcaaaaaat
     1201 gactacctga aatttagcac aacgcataac aagttaagac taacttgctt ttcgctctcc
     1261 tcatctctat tcttagtcga acacatccac acgaatggtt acccatagag aaattctttt
     1321 acttaatcag cttcacactg ctttttctac tttcgtagtt gaaaaaaact taaacaaatc
     1381 atcggcaaat agttaaagaa aaaacttaag cgttgaaaga agcccaattg cttaaagaag
     1441 gcaaactgac taatcgacgg aatccgtgct aatccgtaaa gacctgcaat tagtaaacta
     1501 ataactgtta aaacaagata aaaatggcta agcgtacctt gaccactttg acgataaagc
     1561 agaacaagta acaatgggaa aagtagaaag cctgcatagc ctagcccaga acctatatta
     1621 tggatccaag tcgatagatt ccaagagctt tcattcgtat tgatactgaa taacccagta
     1681 aaaatacaat cacctatccc atataaacca actgttgcaa cagcaagtat tgcaagtgtt
     1741 tttgatgttc caataaatag gtgatacaac gcaggcaacg aaagaacaaa aaaaagtcca
     1801 gatacaactg accagaccaa gaaagcacgt ctgactggac tatctacgtc accaaacaca
     1861 ctaattacgg tagtcatttg attcagtttg ggataaaaaa ggccaaggat atacggtgtc
     1921 gataaatcac taatcacacc taataataaa aaataaaaac catatttttg caaaaaaatc
     1981 attttcttct cctacttttt agtgattatt cgatacatcc aacaatcaaa ttttttctca
     2041 ttttaacaca tatttttatt ctagttgcct tttgaacaat caataacata aaggtgagtt
     2101 tcttctacat tttaaaaaat cgaatggcac tgaagagttc agttgtcagc atcaatctcc
     2161 tactcaaaaa ggcaaaaaaa cgtaagtcag atgttgttga catctcactt acgcatccat
     2221 tgattgaaaa tttcttagta aaatctacta gcctaaaaat ttgaagactt cttctcgatc
     2281 atacagttta aatactttct cgcataaaaa ttgagtaatt agtgccgcaa aaacagggat
     2341 gactaaccaa caaagaacaa caagaaagcc atttagccct gcatctaaag aagccaacgg
     2401 accaacaagt ccgaccacgc cgaaaccagc agaagcaggc gtacctgaaa tagaaaatag
     2461 agcgacagga atagctgtaa tcactgcact aactaaacaa ggaataagaa tcacaggttt
     2521 tctaaataga ttaggcatca tcatcttcat agcgcctaaa gcaatcgcaa ttgtcacacc
     2581 tgacttatta accttccaag agttcactac taaaacaaaa gtggttgcag ctacgcccat
     2641 cgcagccgca ccagcagaaa caccatctag ttggattgcc attccgattg ctactgttga
     2701 aataggagag ataatcaaaa aggcaaagga acaaccaatc aagatagaca ttaacagcgg
     2761 ttgtaaggta gtgaagttat taatcaatga tccaattgca gaagtaattg ctgttacaaa
     2821 agggaataaa taaaaaccaa gtaaacctgc acctacacct acaacaatcg gtgttaacac
     2881 aatcgacact gacccaaaac tatttccaat cagtaaaatc agcccgacag caatcgatgc
     2941 tgtcagcatc gtattaataa tatcgcctgt accagcacca acgtaaacac ccgtttcacc
     3001 caaatcaggt gtgaatttga ctacaccaga accaacaaaa gaagctccgg ctacaaccat
     3061 cattctcatc ggatcaaatc caaattgtaa ggcaatcaaa ccaccaatga tcaaaggtgt
     3121 tgctagttga aaaataactg ctaactgtgc gatcgttacc gcaaagggat acgcactaaa
     3181 atattttaaa atggcaccta atactgcatt aggaatcaat ccaataatga ttcctgttgc
     3241 tgtaccagcg aggactttat tcagaaaaat tttcggtgat attttttgtg aagtttccat
     3301 tcaatctctc ctttatttta cgttcaaact atcttctttt gcatggacaa gctcagtcaa
     3361 gaaatcacaa taaggcgtcg caacaccata tttcttccct tttctagaaa ttgcgccatt
     3421 gatataatcg atttctgtta atcgatggtt cttaatcaag tcttgataca ttgaaggata
     3481 atgtaaccca attgtttccg ggtcaaaaca agattcacaa tgtgcaatga cttctgggac
     3541 atctagttca atcttctcta ctgctgctac tttggcaaac tcattgacaa tcgtcgccac
     3601 cattttatga gcagtcgatg tttttcctag ctcagccata ttaacgtcta agattgtgca
     3661 tagtccgttc attgttccgt tcacacatgc tttgcgataa atagaatagt gaatattgtc
     3721 agaaaaatga gcatttaatc ctgattcaga caatttgtct gctaattttt ttgcagctgc
     3781 ttcttttcca tcacctaaat tttgtaattc tactgaacca cttccaaata atttgacctg
     3841 accaggacct tcaagacctg ccgtccacat ggtatttcca atatagatat tttccattgg
     3901 tacaaatttc tcaataatat cttcatgccc gataccattt aatagacata agacctctgt
     3961 atcttttttg attaatgatt ggatatcctg cagcattttt tccagctgca tcgctttggt
     4021 aaatagaata atcagatcaa cttgatcttc tttttctact tcggattgaa gaacgattgg
     4081 tagttttgct tctacctctt taccattaaa atttgcttgt aatccatgct ctttgatttg
     4141 ttggacatgt tctgcccagc catcgattaa taatacttcg ttcccacttt ggtgaagcat
     4201 taacccaaag cgacttccca ttgcgccagc gcctgcaatt gctattttca ttgattcttc
     4261 ctcctttttc tttctattat attcatttga gaatcatttc acaaccttgt tttgttattc
     4321 ttctcttatt tatcatgttt atatccacca ttcaagttat tttatcagca aatcaataaa
     4381 aactggaata gaatcccaat ttcatcgtaa gagaaactag actagcaata agaaaataga
     4441 aacattcata gaaaaaacct cactcctctg attataaaag agggggcatt aacctcgtgt
     4501 atactaaaac cttccattca ttcgatggat gattttcttt ttgtgaaaaa atattcattg
     4561 tagtacgatg ttgcgcaaca cagacggatg gtattgctta ttatttatta aaatcgaaca
     4621 atacacttat ttaaaaactt ctttcccaga ttttcttcca tttttacagt tataactagt
     4681 attatcatga aaaatagcct tttattgtct atgggaataa taatttaaaa ttggtacttt
     4741 tttattaatt agttcatcgc ccaataatct ctccagtttc ttagcatctc ctgactcaac
     4801 cggaattatc caagcccagt ccaaataatt ttttaaaatc tcatcatatt ttgcaaatat
     4861 ttcattgcca tattccgtcc ttaaaattat attttcagtg ccagacaagt gatttgtatt
     4921 gagttgataa aaaagatctc catctaaaaa aatatcatta gaagaagatt tccccacagt
     4981 aatgaccatt ccatcagctc tatgtgttac atacaaataa ttgtatgacc tcatttcacc
     5041 taatgaatca attatttctt gccctttagc tctaatatat tgatctctat tacctatctc
     5101 actcttattt aacaaaagtt ttttcatgtc aaatttaatc ggctgtttta tttttgtaaa
     5161 ttcgcttcta ctactaatcc aatccgagat taatttttca acatgtccca gagtaaactc
     5221 tgatttattc gctaaatact ttttttgttg tattaaagac atctttcccc gaagctcaaa
     5281 attgagccta catcgattct ctatctcttc aaaaagcatc ttatcttcat cattcttata
     5341 ttcatcattc ataaaaccaa tccagctcct cgattaagat aatattttaa tctcatacaa
     5401 aaactagctc tcatcaaaac aaccattgtt ttgatttctc atgaaatttc tttatacttt
     5461 tctccgatta taaattccta accccttgag aaaattacgc atatatttat ctccgcaagg
     5521 cttaaaattt cgttggcctt cttttctcaa aaatgccccg atttcgcctt ttgatggata
     5581 gatttctgcc tcagcaaaaa cgtctaaaat atcatcagtg gtcatagaca aggcgatttt
     5641 taattttttt agcaacacat tgttgatata tttgatttcc ttgctttttt gcggcgtgtc
     5701 tactatcggc ttatcttttt gcggaccacg cgccaagaga atcaggccat ttaggaatgc
     5761 gtcaaaaact tggttgttga tggttttttc atacacatta ttttctgcat tatctttgtt
     5821 cttatcctgt actttggtca gtaccgcctg agcttcttct ttagtcagtg gtacaccgcc
     5881 tagctcaaaa gctttaatca aatccgtatc tttcaaatca atcgcataac gcaatcgcaa
     5941 taacctatca ttgttattca tttgttcctc cgaagtattt agtctttact ttcttacgta
     6001 ctttttgtct tgctaagatt tttaggatca atgataaaaa ccgcatcact tatgataagg
     6061 cgcccccgca ttgatccgga aggcacggta gatttgctcg acaaggatca gacgcatcaa
     6121 ttgatgtgga tacgtcattt ttccaaaaga gatctgagca ttgcttcttt tcatgacggc
     6181 ttcgctgagt cctaaagagc cgccgataac aaaaacaagg tggctttttc cttggatacc
     6241 taattggtcg atttgtttag caaaagattc acttgtagga tttttccctt caattgctaa
     6301 ggcatagacg tattcttgtt ctttgatttt cgctaagatc cgttcccctt ctttttcttt
     6361 tacttgtctc atttgcgctt cgcttaaatt ctccggggct ttttcgtcag gaacttcgat
     6421 caattcgatt tttgcatagg cattcagccg tttgacatac tcattgatac cttggatcag
     6481 gtatttttct tttaattttc ctactgagat aattttgata ttcatgtttt ctctcctttg
     6541 gtcttcatgc tcactttgtt tattataatc aattttttcg tctatatgtt tattttggct
     6601 atttttgtta aaaagatttc cccaacagtt atgcacaaca tccacaggtt tatccacaga
     6661 aaacagtgtt attttacctt atttcatcac attcattagg caaacatacg ttttataaga
     6721 atttatccac tttatacaca ggctgtggat atgttttatc ccttattttt ccaatcctat
     6781 ccgcgtagtt ttacacagta tctgtggaaa aagaaaatca aatattttca tctgaaaaca
     6841 atgatttttc ctaaagtttt tcataaaaag ttcacagtct caaagtagac taaagtcaac
     6901 aaataagact atactaacag tagataaatg aatgtaattg gaggaggaac acatggatag
     6961 aaaaaatgtg acaccaaaga tgaaaaaaag taaaaataat agcctctggc gtaagttagg
     7021 tctggggctt gttggaggga tcgttggagg actactgaca gctggcattt tttatgcagc
     7081 gatgggcact ggcaacaata gttctactgc tacaagcggc aatcagaatt ctgccggtga
     7141 aacagttgtg gaaaatgtca aagtcaatgt agattctgat atcaccaaag cggtagataa
     7201 agttcaagac gctgtcgttt ctgttatcaa cttacaaagt caaaaccaat caagcggttt
     7261 tggcggacta ttcgggcagc aagaagaaag tagcagctca gatgatagta atttggaagc
     7321 ttatagtgaa ggaagcggcg tgatctacaa aaaagacggg aatactgctt atgtagtcac
     7381 gaataatcac gtagtagatg gccagcaagg tcttgaagtc ttgatgaaag acggtacgaa
     7441 ggtaaaagct gaattagttg gaacagatgc ttattcagat ttagcggtgt tgaagatcaa
     7501 ttcagacaaa gtcgaaacag ttgcctcttt tggtgactca agtgctctga aggttggtga
     7561 gcctgcgatt gcgattggtt ccccactagg atctgaatat gcaaattctg tcacttcagg
     7621 aatcatttct tccttgaacc gacaagtgac aagtacgaat gaatcgaacg aaacagtcaa
     7681 tatcaatgcg atccaaacag atgcagcaat caaccctgga aattctggtg gtcctttagt
     7741 taatatcgaa ggacaagtta tcggtatcaa ctcaagtaag atcgcaagta cttctgaatc
     7801 tacttctaat gtaagcgtag aaggaatggg atttgctatt ccaagtaacg atgtagtgaa
     7861 tatcatcaat caactggaaa aagacggaaa agtgacacgt ccagctctag gtatcacaat
     7921 ggtcgactta tctgccgttt ctactcagca acaagaacaa atcttgaaga ttccttcatc
     7981 tgtaactaac ggtgtcatcg tgacaaatgt ccaaacagct acaccggctg aaaaagctgg
     8041 attgaaacaa tacgacgtca ttactaagat cgatgacaaa gaagtttctt ctggtgtaga
     8101 acttcaatct gctttgtata agaaaaaagt gggagattct gtcaaaatca cttactatga
     8161 aggctcgaaa gaaaaaacaa ctactgttga attgacgatc gatcaatcgg cattaaaaca
     8221 aaatcaaaat agtgaaaatt aataaa
//
LOCUS       DAMEEU010000101         8228 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.103, whole genome shotgun sequence.
ACCESSION   DAMEEU010000101 DAMEEU010000000
VERSION     DAMEEU010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 8228)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8228)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8228
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.103"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            328..1251
                     /gene="truB"
                     /locus_tag="PB779_002565"
     CDS             328..1251
                     /gene="truB"
                     /locus_tag="PB779_002565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HDE0740058.1"
                     /translation="MDGLLTLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEEKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVKRFKRVDITDEVWQKVKNGMRLNYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1255..2196
                     /gene="ribF"
                     /locus_tag="PB779_002566"
     CDS             1255..2196
                     /gene="ribF"
                     /locus_tag="PB779_002566"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HDE0740059.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     EQGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKS
                     TVHLPKEGVYVSEIKIGEIWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVA
                     VRWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2591..3376
                     /locus_tag="PB779_002567"
     CDS             2591..3376
                     /locus_tag="PB779_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HDE0740060.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWINNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENDKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3389..4240
                     /locus_tag="PB779_002568"
     CDS             3389..4240
                     /locus_tag="PB779_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HDE0740061.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4364..4816)
                     /locus_tag="PB779_002569"
     CDS             complement(4364..4816)
                     /locus_tag="PB779_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740062.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQIREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNHVVNFSQWINEKLLMQTDISLVS"
     gene            complement(5281..5649)
                     /locus_tag="PB779_002570"
     CDS             complement(5281..5649)
                     /locus_tag="PB779_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HDE0740063.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5799..6281
                     /locus_tag="PB779_002571"
     CDS             5799..6281
                     /locus_tag="PB779_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HDE0740064.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6318..7328
                     /locus_tag="PB779_002572"
     CDS             6318..7328
                     /locus_tag="PB779_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HDE0740065.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPPWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQPSEKYQKEWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTISHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7443..8156)
                     /locus_tag="PB779_002573"
     CDS             complement(7443..8156)
                     /locus_tag="PB779_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740066.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIKQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLINVIVMDN"
BASE COUNT         2784 a         1337 c         1667 g         2440 t
ORIGIN      
        1 ttaagaaact gaaaaaataa ataaaaaaaa acggaaaaaa gactggaaga atggacagtc
       61 ttttttttcg tttttgggaa gtgaaaacca aactatttac ctgtaagcca cccataaatc
      121 caatcaaatg gtgcaaagaa aaaatcttcc attctattcc ctcctttaaa aaaaacataa
      181 catgatttct atttacgtga gcatgaattt tgttacgttt ttattgccga aaaataaaaa
      241 ccgttcatta tgatgtcaaa ttcgtcagta attgatgcaa tgtgttataa taattcagtt
      301 aaatcaaaaa tgaaatggag aaaagacatg gacgggttat taactttatg gaaagaacgc
      361 ggaatgacaa gtcatgattg cgtattcaaa ttaagaaaaa tcttacatac gaaaaaaatc
      421 ggacatgggg gtacgcttga cccagacgta gacggtgtgt tgcccatttg tattggaaaa
      481 gccacaaaag ttatcgaata tttgacagat tctgggaaaa tctatgtagg cgagataact
      541 ctaggtttca gtacaacgac ggaagatcga tccggagaac gggtagaaac aaaaccagta
      601 gatatgtctt tatctgaaga aaaaatagat gaagtgatgg cttcatttat tggtgagatc
      661 acccagatac caccaatgta ctcagcggta aaagtcaacg gtaagcggtt atatgaatat
      721 gcccgcaata atgaaacagt ggagcgtcct gttagaaagg ctcagattta ccgttttatc
      781 cggacaagtg aattgacaag agacgaagtg acaggaacca tttcttggcg cttcgaagta
      841 gaatgcggga aaggaaccta tgtccgcaca ttagctgtag atacaggcaa gaaacttggt
      901 taccctgcgc acatgtctga tctgacccga acagcaagtg ccggtatgtc ccagaaagat
      961 gctctgacat tagaagaagt agctcaagct gtgaaaaatg ggacaatcga tgattgtttg
     1021 ctgccaatag aaaaaggagt gaaacgattc aaacgagtag atattactga tgaagtatgg
     1081 cagaaagtaa aaaacggtat gagacttaat tatactgtat ttgcgctccc agaaatgccg
     1141 tcagaagaaa ttgctttgtt ttataaaggc aaagttgtca gtatctatca gccaaacccg
     1201 aaagaaaaaa acaaattaaa acctagtaaa gtattgagaa atgaggaata acgaatgaat
     1261 atcatcaaga tcagacatcc ttaccaatca gaacaaattc cagaagacga tgtcgtttta
     1321 gtactaggat tttttgacgg cgtgcatatt ggacaccaga aagtcataaa gacaggtatg
     1381 gaaattgcac aaaaagaagg attgaaatta gcattgatga ctttcaatca gcatccatcg
     1441 attgtcttta aaaagatcga tcctagcagc gtgaaatatt tgactagcct taagcaaaaa
     1501 gaagaaaaaa tggccgcttt gggtatagat tatttatatg aagttgattt tacttcttct
     1561 tttgctcatt tagcaccgca ggaatttgtt gatcaataca tcgtagggtt acatgcaaaa
     1621 tatgctgttt ccggttttga ttatacgtat ggaccaaaag acattgcaga tgtcgctcat
     1681 tttcctgaat atgccaaagg aagattcaaa atcgtcacag tttctaaaga agaagaacaa
     1741 ggtgaaaaaa tcagctctac ccgtattcga ggattactag acagcggaca agtaaaagaa
     1801 gcagcaaaac tattaggttg cacatatgag gtagaagggg tagttgtcca tggcgatgca
     1861 cgaggcagac tactaggatt ccctacagca aatgtcaaag taaagagcac agttcatttg
     1921 cctaaagaag gtgtttatgt atcggaaata aaaattgggg aaatttggta tccagccatg
     1981 ggttcaattg gacataatga tacattcggt gaaggacggg agctgactgt agaattgtat
     2041 attttggact ttaatcaaga tatctatggt gaacatgtcg cagtacgctg gaatcaattt
     2101 ttaagagatc aagtgaaatt ttctagtgta gaggaattga ttgaacaact caaagaggat
     2161 gaacaagcaa cagctgaata tttttctcag caataaaaca ttatgcataa aatctcttgt
     2221 ttatgtataa ctagcaattt caataaaatg ggtgataaat aagcccagga aaggggctgt
     2281 gacaaaagtc ttgtcacagc ctttttttcc aaataaatgg tttttcagaa gtagcttctt
     2341 cggaaataag ccgaaatttc acaaaaattt gagaagtaat ttttgtaaat tacttcttat
     2401 ttcttgaagc tggccacttc tgtcacaacc tctttcttta tagaaataaa aggacactag
     2461 caattcatga aaacgattgc taaagcgtat catttgcttt agactatata tcttggtgta
     2521 cactcacttt aagacggaaa taaaagttat ccgtaataac aggtttaggt atgaaaaagg
     2581 agtgggtact atgtataagg aattagaaaa caaagtcgca gtagtaactg gtggctcaaa
     2641 ggggattgga acagcgattg ctcaacgatt cgggaaagaa aaaatgaatg tagttgtcaa
     2701 ctataactcg gataaagaag gagcagaaaa agcagtcaaa gcaatcgaag aggcaggcgg
     2761 aaaagcagtc tctgtacaag cagatgtcag ttctgaagaa ggaatacagc gtttacttga
     2821 tacggcttta gaaaattttg ggacactgga cgtttggatt aataatgctg ggatggaaaa
     2881 tcagcatcca acccatgaac ttagccttga agattgggaa agagtattaa aagtcaattt
     2941 gactggcgtt tttatcggaa cgaaagcggc tttaaattac tttacagaga atgataaaaa
     3001 aggaaatatc atcaatatgt cttctgttca tgaacaaatc ccatggccaa cgtttgctca
     3061 ttacgctgct tcaaaaggcg gagtaaaact attcaccgaa acggtagcaa tggagtacgc
     3121 accaaaggga atcagaatca atagtatagg acctggtgct atccgtacac ctattaatgc
     3181 ggcaaaattt gatgatcctg aacaaaaaga actcttggaa agtatgatcc cactaggacg
     3241 cgtaggtgaa ccaaaagaaa tagcggcgac agctgcatgg ttggcttcag acgaatccag
     3301 ttatgttaca ggtattacac tatttgcaga tggtgggatg actttatatc cttctttcca
     3361 aggtggaaaa ggataagggt gaataaaaat gggtttattg attgcattga tcccggcagt
     3421 tgggtggggg atccagccac tgattttgaa aaagattggt ggcagaccaa caaatgagat
     3481 attaggaact ggtattggag ccgtgctcgt tggcttactt gttcaattat tcgcttctcc
     3541 agctggtatt tcagtgacta catttttgat tagtttactt tctggtgcat tctgggtcat
     3601 cggacaaaca ggacagtata catctttcaa cttgattggt gtttctaaaa cgatgccaat
     3661 ttcgactgca ttacagttag tcggaacctc attgattggt gtcttcgctt ttggagaatg
     3721 gtctggaagt atgggaaaaa tcattggtgc agcagcaatc attcttcttg tatttggttc
     3781 tgctttaacg gcaatcagtg atgatcctgg aaaaaaaggc ggtatcacaa aaggaatcag
     3841 tctattagca tcaacaagta ttggttattg ggtttacagt gcattgccca aactagttga
     3901 tgcaagcgga ctttccattt tctttccgca aatgatcggt gtctttttag gggcagtgat
     3961 ttatgtgatt ttccgaaaac caaccgcatt ttctgaagac aagagttgga aagcaacaat
     4021 agttggagcc atcttcagtg tgtcagcatt ggcttatatt ttttcagcaa atgaaaatgg
     4081 ggttgctact gcatatatca ttacacagct aaacgtagtt atctctacat taggcggtat
     4141 gtacatcctg catgaaaata agacaccaaa agaaaaaaaa ttaacgatta tcggattatt
     4201 gctgatcgta gtaggaagca tggtcacggt ctttatttga ggataaagat ggtaaaatct
     4261 catttattaa aaaaatattt gtttgaacca aacagtaagt acttataaaa aaatagcgct
     4321 agaatttcca acatctctgg aatttctagc gctttttaat tgtttaagat acaagtgaaa
     4381 tatctgtctg catcaataat ttttcattga tccattgact aaaatttacg acatgattga
     4441 agttaccacc gattagtatc tccgcatgat tgtctttata aagatcgtat tgtaaaagac
     4501 ggtctttttt atttgcgtaa acatcgttat ggtactggac taattgttct cggatttgat
     4561 tgattgctgt aaaatcacga tactgaaggt tgaaacgcat cgtgattggt gcatttagca
     4621 tgaatcgctg catttctttt gctgcttcct ctgcttgatc tccgtatagg aactcaaaaa
     4681 gattacgttc agaaaatttc cattgcccgc caacctttgt tccttttagt tttccttcat
     4741 gaagataatt tctgatagaa cgtgtagtaa cacctaattg ttcggctaat tcatttactg
     4801 agtaaaaatc tttcaatgtt caccctccta tgtgaatggt tctactgact tagttgatat
     4861 ttgcttaatc acgaaatgta gaaagaacga ttttaattaa ggtcattgta aaaatcaagt
     4921 cagaaaattc taacttttct ttctctaaag aaattcgttc tctcctaaag tgatattata
     4981 tttaaatata cctgaaaata atgggcagta ttatgaaaga tcactgatat tttctcgtat
     5041 tttttcctta ttcaaaagtt ttgcaggaaa attgctgaaa aaataatttt actaagtgga
     5101 aaattcaaag ccattcaatc agtgattttt ttcagcacaa gaaagactcc ttataaaaat
     5161 agcagatact ttgtcaatta agtgtttaac cagggatgat aaaaaggata ggattgaaca
     5221 aaacctgtat aagctgatga atagtttcct cgccagtaaa aggtttattc gtataaagct
     5281 ttatcgccaa aatttatcat gacctttttt atcttcaata ttaaatgaaa tcaattgttc
     5341 aatcaattcc cagttgatta cacttttcca aggaactttg atgacgttat ccgtatatac
     5401 gtagcctgct tcttggatat ttttttcaag ggcacgaatc gctgcttttt ccggtgcgat
     5461 agaaaaatga tttttagcaa aactaaatgc aataataaag gtaccatggt cagtaaacat
     5521 aggttggttc cattttacag ttgtgtctag ctggggatac gtttctgtta tcttagcaaa
     5581 aaggtctttg atcttttgtt gatgttcttt ttctttgatc tgattgatga tcggctgaaa
     5641 tttttccatt ctaaaacgcc tccattaagt ggtttgattt attttaccag aaaaacaata
     5701 gttatgtata aaaaacgaac aaaacacaag taatgttgta accgctatat ttatatgata
     5761 agatgtctca aataataaaa tagaaaagag acataaaaat gattgacttg gcaaagaaat
     5821 tcttacacga aaatatatat tttgagttgt atcatcatcg agccatttat acaaatgaag
     5881 atgctttggt aataaagaaa gaacaaggat ttacaggtac agagaccaaa agcttattct
     5941 taaaagataa aaaagataat aactacgtat atctgacttt tactacgaaa caaacggatt
     6001 tcaaagcatt agggaagatc gtcggtaaaa ggctttctat tgtttcatca gaacgcatgg
     6061 aagaacaaac gggacaaaag cagggcgctg tttctccgtt tggttatgaa aaacagattc
     6121 cgattattat tgatgaagag ctcttatcaa atgaaaaact tgtttttgca ccaggtagac
     6181 cagatcaaac gatggtcatc caaacggttg acttaaacaa aatcatccag ctacttgaga
     6241 tgccgatatt tttgatgccg gcaaacgaaa aaaacaatta accaagtaaa atagtgcata
     6301 cttggaggtg aagcaacatg ataagttatc cattattaga aagaaatgca acgattgggg
     6361 ttactgcacc atcctcaggc gtatcagagg aacaccattc gttactcgaa tcagctttaa
     6421 agagaatgga agaaaaatct ttccaagtag ttactggaaa gacgctttgg acgcaagata
     6481 aggaaaaatc aggtccagca agaaaacgag cagatgaatt caatcaaatg atgcaagatg
     6541 aaaatatcca aatgatcttt ccgccttggg gaggagaatt attgattgag attctcgatt
     6601 ttgtcgattt tgatgctcta caaccaaaat ggatagtagg ttattcagat attagtacgt
     6661 tgctacttgc tgtcacatta aaaacaggga tagccactgc acatggaacc aaccttattg
     6721 atttaagagg agagtacttg gatgaaacga cagcaatgtg ggaaagtgta ctgaaaacaa
     6781 gagaaggaga atcgattcta cagcaacctt ctgaaaagta tcaaaaagag tggccccatg
     6841 agcattcatc atcttctgtt ttccatctca ctgaaccaac aaattggcaa tcagtcagcg
     6901 gagatgcagt aaggatgaag ggacgattat taggtggctg tattgatacg atcagtcatt
     6961 taatcggtac cccttatgga gatgtccaat cttttaaaag aaagtataat gatggaaagc
     7021 cgatcttgtg gtttctagaa aattgtgagc tatcgtcagt tgatttaaga agatcacttg
     7081 ttcagatgaa actggcagga tggtttgatg gcagctcggg gatcatgttc ggtagaagtg
     7141 cagcagagga tttgttagat tataaaatga aggatgtata tgaagatctg tcaaaggaat
     7201 taaaactacc gatcttgtat gatattgatt gtggtcatgt accgccacaa ctgacattga
     7261 tcaatggtgc ctatgcagaa gtagcggtag aagatagaaa agcgactgtt ttgcaaacgt
     7321 ttatttaaaa aattttttcc tgccttggag tttatcaaag accaacaaat ctaaatagaa
     7381 aagaaaatga aagaagctga cagtattttg ccagcttctt tttgtatgat ctattagaaa
     7441 ttttaattat ccataactat cacattgatc agctgtttca catcatttgg attacctgta
     7501 ggaatagcta ctacagatgc attatcaata atttcttgag ttgtttctct aatgaacgct
     7561 ggataagatg tttgatctgc aggcatttgc caatgtgaag gaactggata actagtgatt
     7621 gtcccgtcat ggttacttga atacactaaa actccctggt aactgtattt cccagtgagc
     7681 ataaccacat ctttcggata gactgcactc cctgcatcat aaggggcgat aggtgttcct
     7741 gcaggataat gaataacatg tagttcgaaa tcacccgatg tatctctaaa agtattacct
     7801 ctaattgcta gccaaacacg tgcgtactca atttgtagat cagaatatcc tgctaacgga
     7861 tctattgact gagaagactg tgaggaagtt gtgtctattg ttgaagaaga aatatttgtc
     7921 tcaactgtac tactagatgt agaagaagta ttgggctctg agactttact gcttgttgaa
     7981 gatgtattcg tttcagtaga agctgatttc tgagtacttg atttttcagc tgaactggtt
     8041 tgtttgattg aacttttgtc tgtggtcgca gatggatcac tattttcttt actaggagac
     8101 gtacatccta caaggaataa agagaccaac aataaaataa aacctaactt tttcatataa
     8161 aatacctcat tattttttta ataccagtat agcataatcc tgaatttttg aatccgtaaa
     8221 accttgtc
//
LOCUS       DAMEEU010000102         7771 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.105, whole genome shotgun sequence.
ACCESSION   DAMEEU010000102 DAMEEU010000000
VERSION     DAMEEU010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7771)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7771)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7771
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.105"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..2008)
                     /locus_tag="PB779_002574"
     CDS             complement(<1..2008)
                     /locus_tag="PB779_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDE0740067.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKILTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQK"
     gene            complement(2024..3020)
                     /locus_tag="PB779_002575"
                     /pseudo
     CDS             complement(2024..3020)
                     /locus_tag="PB779_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            3218..4459
                     /gene="sstT"
                     /locus_tag="PB779_002576"
     CDS             3218..4459
                     /gene="sstT"
                     /locus_tag="PB779_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HDE0740068.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            4606..5241
                     /locus_tag="PB779_002577"
     CDS             4606..5241
                     /locus_tag="PB779_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HDE0740069.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            5432..6172
                     /gene="truA"
                     /locus_tag="PB779_002578"
     CDS             5432..6172
                     /gene="truA"
                     /locus_tag="PB779_002578"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HDE0740070.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(6317..7696)
                     /locus_tag="PB779_002579"
     CDS             complement(6317..7696)
                     /locus_tag="PB779_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008270028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740071.1"
                     /translation="MMGNLVLSYNIYYFFITFLTMVVSYFSMKQIKNNRYISLLFSII
                     YTFSAYRAIDIFHRASLGEAVALTFLPLILMGCYEIYIRDYQKWYWLSIGMTLVVYTH
                     LLSVAMVSVFIGGTLFLSFYFWDQKIARLLSLLKATVLTFFLSAGFLIPFIQQSRAQE
                     LKVPLGKELSGMAPSDMLTHILNNNYNNYTIGLFLFLGLIGAFIFIKKLTADDLFIFF
                     LGVFVLFCSTNLFPWQLFNHTPVKSLQFVWRLNGFSSLFIAYTMSIVIYYIFSTKNNS
                     WKIMVFTFLALILHLSGVSNSIHANKDSLTLIAPEDAVAIAENYNHTDYANKESIYHP
                     DMINNDQYLLGNQEINPTTHFMSNKLTIELDNSNNKNTVLTTPIYRYKGQVASINGKL
                     VQTKLSKFGTTELTIPPGINKVVITYQYTKLAIASRYLSIVTLILFLLYRFTFSKQKQ
                     PRREVQHSH"
BASE COUNT         2559 a         1216 c         1456 g         2540 t
ORIGIN      
        1 ttttttgtgt cgcccatgtt gcactgtact ggttacctgc aacaagatca tattgtatca
       61 gacgataatc ttctagaatt tctttttgtt tctcagttaa atttttttct tggataattt
      121 gactatcctc tgtaacaaag acctgttttc cattaaaacg attagacaag ctttctgtag
      181 gatcaattgt taatgcaggt agatgattag atacttctgt caacaacgca tagtaaggag
      241 ttactttgat attcgcatgc tcaagagcca tagcaccaaa gttattagga gcaacaactt
      301 ctttatttaa cgtagctgct tgttcacgac tatacttgtt gttataaatg aaataatctg
      361 tctggtgctg ttctaatcca tattttttcg aatcattccc actatagatt gcgggtaaat
      421 ggtcaccata aaaaacaaag gtaatcggtt tatcgatttt gtcgatttct tggatgaatt
      481 tttttactgc tgtatcggta tagtgaaggc cttgcatata agtttgtaat tcttttcttc
      541 tattaggaat gacagcagtt ccttcagcag tgtagttcaa ttcactatag taatcatcat
      601 aaggcatatg gttttgcata gtggataatt ggatgaattg tgacgtttct gtattgcttt
      661 gtaaagcttt caaggtttct ttgtatgctg aatcatccga tatgcgtggg ctttgttcta
      721 ttttatccgt ataagttaat ttatccggac tgtctaaata atagaacctg tcaaaaccaa
      781 atttatcaaa cacttgtttt ctgcgataaa gagcagctgt aaaaggatgg atggctattt
      841 tttcatcgaa tagatcggta atatttggac ttattttctg acgctccact agctgggtat
      901 aaggtgtaac taacgaagca gacaggttac tgatactcaa gcctgtcagt ccttcccatt
      961 ccatgttagc tgttccgcca ccataaccga cggataacat caatcctcct gttccttctg
     1021 ttataatgct tttgatgtaa ggaatagggt ctgtaggtac tgtcagatta gggacacgtg
     1081 caggatcact gaagctttca cttaaattga gaacgatcgt ctgattgttt aaccagtcac
     1141 ttcttgtttg gttgatttca tctgcctttg tgttgtactt tttcattatt ccattaattt
     1201 tttctttcga atagccagca ggttcttcca tgattttaat gtcgatattg tttaggaatt
     1261 gaatgactgg tccgttatct tttacggcgc cttgctggtt aaagaaagtc ttgtttactt
     1321 taaataaatt aaacagcaag aaagaaggcg aatttttgtg attaatgaaa aagacacccg
     1381 aaaaacatcc taataataca gcgatactga taaatcgacg tttccaatga atcttcaagg
     1441 aatactgttt ttgtagtcta cgttgtacaa taatactagt aatcaataat aggagaagga
     1501 tcaatccgcc cacgattaat aagactgggc taaccatcga taatagttct gacaatccgg
     1561 tcagtatttt taaatctgaa ggaaagacag gctcttcccg catttccatt ttgattactg
     1621 tcgaaatagt gagcagtaag ttaatgatca aggtagcagt caaggcgtac caaaaacgat
     1681 tggaaatcaa caatagtaag aagaaaaatc ccataataat gatgattgtc aggatcatgg
     1741 gtgcttgtcg ctgagtaaat atttttaagg caacctggat agtttctttc caaccttctt
     1801 ttggttctaa aacgaaaatc tgcacgaagg taaagcagta aaaaaatgct gcaactaaaa
     1861 aataactttt atgaacaaaa agccaatgaa ttcttttttt ccaacgctga gttaattgtt
     1921 caatcgaatc aaaagcgaag tattcgatga aacgatgaat gaaacggatt ttttgtatat
     1981 aaaataaaaa gataactagg agggacactg ctaataaata gcaaataaaa aactgcccga
     2041 tatttatcag ccatgccttc cctgagtttg gaaattcacg tttcataaat gtagatacgc
     2101 gataagaaac taaagggaaa ttacatataa cttgagtgac aatcaaaaat acagcaagaa
     2161 aatttcctct tccttttata cctaatttat cagatagcat ttctaaaaat aaaaacgaag
     2221 agaaagtata atacattgcg aagagagaat atggtttaga aaacctcagc gctgtatctg
     2281 tatttcctct gatgatgagt gaaatttgtg tcatcaaaat aatcaaaccg aataaaacaa
     2341 tcaagctgat aaatacttga ggaagcttat agcggacctt ttctttccag ttccattctt
     2401 tcaaaccata acccattaaa aataaataaa aaatccataa aatactctgt ccattctgta
     2461 atgcaaacgg gtctttatta aatagagtag agcagccaac taatccaatt gttaaaaata
     2521 atagtagata tttaattgtt gttttcgata atttatttaa aaatccaact gtataaggaa
     2581 tactacaaaa aagcaaagta caagaaacag cataagtaaa gtaattctga ctgataggtg
     2641 ttaggataag ccaataatca cgaatattca agctgccagc ttgtacgtaa aaaaaagata
     2701 ttgcaaacta gtgtggctat taggaatata aaggcaaaac gacttaaata atgtaaaact
     2761 tttaaacggg cgattttttg atattggtaa cccatgtaaa gtgggatcaa atttgcacca
     2821 ataacaacgg aagtttgtaa aaatgtatag atgtagaatc gaccagggtt tgttgcatat
     2881 gtaggaatag tgactgctga aatcaatata cgctgtaaaa ccatcattat acaagcgaca
     2941 aagattgtca ggaagccata actctccttc tttatttttt tcaagaataa acacctcaca
     3001 aaaaaattgg acaaaaacat aagaaaacgt ttcctgataa gttgcccatt aataacatcc
     3061 taacttagaa tatctcaaaa aacaacgtgt agacagaaaa agtacaaaat tagcaagaaa
     3121 tggttgtttg tattgttaga atttttagaa aattatacct ttagtttctt tgcataaaat
     3181 gatacaatga ttgttaaaat tgtgaaaggg tggtcatttg ttagagaagt ttttggatat
     3241 gtcgttagtt caacgtattg ttgttggtat tttagtcgga atattgtttg gtatcttttt
     3301 ccccacatgg acatttattt caatattggg aacgttgttt gtcagttgct tgaaggcaat
     3361 cgcacctatt ctggtttttt tcttgacgat ggcgtcaatt gccaagcata aaattgggaa
     3421 taagacattc gtgaagccta ttttgatctt atatttagtg ggaacattgc tttctgcact
     3481 tgtagcagtt attgtaagtt caatttttac tgttcctatt actttacaag aaacagtatc
     3541 tgaaaaagca ccgcaaagtt tggaaagtgt tttatctact atgttgacga atgtcacaca
     3601 aaatcctgtt caatctctta ttgatgcgaa ttaccttggc gtcttattct gggctgtatt
     3661 gttgggacta gcttttcgag cacgttcaga atcgacaaaa gagttggtgg atcagatatc
     3721 tatagcgttg tcacaagtcg tacaagtgat tattgcattt gctccgatag ggattttagg
     3781 attggtttat caatcaattg ctacgactgg aatagctgga ttggcagagt atctgcagct
     3841 tttacttgtt ttgatcggta cgatgctgtt tgtcgcatta gttgtgtacc cattcctcac
     3901 gtttttgttt attaaagaaa atccctatcc attgattttc ttttgtttga aagaaagcgc
     3961 acttcccgct ttctttaccc gaagttctgc cgcaaatatc ccgataaaca tgatgttggc
     4021 tgaaagattg aaattgacaa aagagtctta ttccatatcg atcccgttag gtgctacgat
     4081 caatatgggc ggtgccgcga ttaccatttc cttgatgacg ttgactgctg tacattcttt
     4141 agggattgaa gcaccttttg ttttgaaagt ccttttatgt attttgtctg ctttagctgc
     4201 ttgtggagct tcaggtgttg cgggcggttc actgttattg attccattag catgtagttt
     4261 gtttggtatc tctaatgatg tcgcgatgca aatcgtcggt attggattta ttatcggtgt
     4321 tatccaggat tcaatggaaa ctgccttaaa ttcgtcaagt gatctgttgt ttactgcaat
     4381 aggagagcta ggcgcgcgta aaagaagtgg ggaaaaaatc aaattgaaag attgtttaga
     4441 tggattaagt gaacgttgaa cgttagatat ttagtatttt taaaatgatt cgagttttta
     4501 atgagttata tagatgttcg tgtaaataga ggtttctgtt aaatcaagat aaagtcgctt
     4561 ataataacaa ttaaaagcat aggtaattgt tattggaggc gtatcatgga ttttttacgt
     4621 aaatttggtt ttttcttttt attattaggc gtgctgagtg attttttgac tccgtacgta
     4681 ttaggattgt attatcctga attagatcaa atgaagagcg tgatcagtgt atttggagag
     4741 gtttccagtc ctgtaagaaa agcgtttctt atttggtctg tggtttcagg gatctttttc
     4801 atcctgtcat tgcctgcatt gtatgctgca tttgtaagta catctcgtgt gttagctacc
     4861 ctagttacag cagccatcgc gttctatggt ataggtgatt gtatctttac aggtttgttc
     4921 agtatcaata cccatgaatc ttcgtggaat gtctcgacat gggtccataa tatcggatca
     4981 ggtttaggtt acagtggttt tttattgttt ccagttcttc ttttcttgat ctatcgaaaa
     5041 aatgggcaaa tggacgtaag ccacttatac cttggactgt ctgtgatcag tttgcttttt
     5101 gcggcgattt atggactggc aagaattcct tctataaatt cttggccatt actgaataaa
     5161 ataggttttt gccaaagaat cagttttttc tttaattatg tgcccattgc ctggttgagt
     5221 atcttgcatc tcaaacagta aaacttgagc cgtcaaattg aacagtcagc ggatacttca
     5281 tccggtggct gttttttgtt tttctgaaat atatatttcc acagttttct tgtatagctt
     5341 ctgttttaga gaagaaagga gctatatttt gtgctacaat cttaaaaagg tagagagaag
     5401 accaaatgga agacagagga gccactaaaa tatgagaaac atcaagttga caatcgaata
     5461 tgacggaaaa agatattcag gatggcaaag acttggagat gacgataaaa ccattcaagg
     5521 aaaaatcgaa aaagtattgc atcagatgac aaatgaagag atagaaatta ttggatcagg
     5581 aagaacagat gctggcaccc atgcgcgagg acaagtagca aattttaaaa caaacacaga
     5641 aattggactg gcagaaatga tcgactttat gaatcgttac cttccgcggg atattgtcat
     5701 caaaagaatc gaagaaatgc ctgagcgctt ccattcaaga tataatgcgg tgggcaaaaa
     5761 atacagctat tatgtttgga acaacgtgat tccttcagca tttgagcgaa accacagctt
     5821 ttatttccct caagagttgg atatggacaa gctgaatgca gcttgcgaaa aattagtggg
     5881 tacacatgat ttcattggtt tttctgcatt gaaaaaatca aaaaaatcca cagtgcgtac
     5941 gattgatgaa ttatctatcg aacgaaaggg agaaatgctt cattttactt ttgtcggaga
     6001 cggattctta tataaaatgg tgcggattat catggggaca ttactagaaa tcggcacagg
     6061 tgccatgccg atagaaacaa tcgatgaaat atttgaaagc aaagtgcggc aacatgcagg
     6121 agaaaccgtc cctgcacaag gtctgttttt ggatgaagtt tattatcgat aaaaatactt
     6181 tgataatgga tgaaacgcat gtttcacagt ataaatatcg atgttaaata atgtatgaag
     6241 caaattaaag aaatataaaa aaagactttt tagcctgttt atgtgtacag ctaaaaagtc
     6301 tttcttaaat aaaaatctag tgagaatgtt gtacttctct tctcggttgt ttttgtttag
     6361 aaaaagtaaa tcgataaagt aaaaataaaa tcaaagtaac gatagataaa tatcttgaag
     6421 caattgctag ttttgtgtac tgataagtaa taacgacttt atttatacct ggaggaatag
     6481 ttaattcagt tgtgccaaac ttagataatt ttgtttgtac tagtttgcca ttaatagaag
     6541 ccacttgccc tttataacga taaataggtg tcgtcaagac agtattttta ttattcgaat
     6601 tatctaattc aattgtaagt ttgttactca taaaatgagt tgttggattt atttcctggt
     6661 tacctagtaa atattgatca ttattaatca tatcaggatg atagattgac tctttgtttg
     6721 cataatcagt atgattgtaa ttttcagcta tagcaacagc gtcttcaggt gctataagtg
     6781 ttaatgaatc tttgttagca tggatagaat tgcttactcc tgagagatgc aatattagtg
     6841 caagaaacgt aaagaccatt attttccatg aattattttt agtagaaaaa atataataga
     6901 tcactatact catcgtatag gctataaata aagaagaaaa accatttaac cgccagacaa
     6961 attgtagact cttaactggt gtatggttaa aaagttgcca aggaaataaa ttggttgaac
     7021 aaaaaagaac aaatacacca agaaagaaaa taaataaatc atcagcagtt aattttttta
     7081 taaaaataaa agcaccaatc aatccgagaa ataagaataa tccaatagta tagttgttat
     7141 agttattatt taaaatgtgt gtcagcatat cactaggagc cataccactt aattcttttc
     7201 ccagtgggac tttcaattct tgtgctctag attgttgaat aaaaggaatt aagaatcccg
     7261 cacttaaaaa aaaggtgagg acggtagctt ttaaaagact taagagtcta gcgatttttt
     7321 ggtcccaaaa ataaaaagaa agaaacaacg ttcctccaat aaatacagaa accatagcga
     7381 cagaaagtaa atgagtatac actactagcg tcatgccaat agacaaccag taccattttt
     7441 ggtaatctct aatataaatt tcgtaacacc ccattagtat caaaggcaaa aatgttaaag
     7501 cgacagcttc tcccaatgaa gcacgatgga atatgtcaat ggcacgatag gcggaaaatg
     7561 tataaataat cgaaaataac agcgaaatat aacgattgtt ttttatttgt ttcatagaaa
     7621 aataagaaac gaccattgtt aaaaaagtga taaaaaaata gtagatatta taacttaaaa
     7681 caagatttcc catcatttta taaaatctta attgtcaaat taagttagac agatcatcaa
     7741 tacttacgta actcaaaaat acttccaaag g
//
LOCUS       DAMEEU010000103         7219 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.106, whole genome shotgun sequence.
ACCESSION   DAMEEU010000103 DAMEEU010000000
VERSION     DAMEEU010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7219)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7219)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7219
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.106"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..1084
                     /locus_tag="PB779_002580"
     CDS             <1..1084
                     /locus_tag="PB779_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HDE0740072.1"
                     /translation="KKIICVKKDGTRFSQEYDKLILATGSKQIMLDVPGNNLANIFSI
                     KNFPNAKEIFKALDDNTIKKVGIIGAGYIGVEIAEAIRKRGKEVYLFDVADRVLSTYY
                     DRSFSDKVEEILSKNGIHLCLSESPKKYLGRKKIEKIVTTSGTQYSMDMVVQAIGFLS
                     NSPIGKKELLRDVSGAYLTNEYQQTNIKDIYAIGDCATTFFTSINRSSVDFSISNALR
                     TAYIATQHIDNQDFTPSGSQFTNGFSIFNYNFYAAGLNLKTARLLSESIDYIEIEDFI
                     RPVFLRKNSRVKLRISFEKNTKRIVGVQLCSQEDLSGLLSMFSLAIEEQITLDKLKML
                     DYLFHPSFSQPYNFILKAVTGLNIET"
     gene            1196..2647
                     /locus_tag="PB779_002581"
     CDS             1196..2647
                     /locus_tag="PB779_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HDE0740073.1"
                     /translation="MKKSLKLASAVILMSQLFIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTLSSESSTTSNAESSTTSSSESSTTSNAESSTTSSSESSTTSN
                     AESSTTSSSESSTISSAESSTTSSSTSEITSSKVTRPNHIESSKKEAPKTEGQTKNFS
                     TPQQIESTESFQSQPILSGNEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIA
                     QAILESASGQSQLAQAPNYNLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYEN
                     YEESFEDYAKLLTKGISGNKDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNEL
                     IKTYDLTNYDKEVKGPQMSKTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIH
                     AVKAGKVVKAEFHYSWGNYVVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGST
                     GNSTGPHLHLEICKDSSLSQSMLVDPKTLLFGD"
     gene            2996..3667
                     /locus_tag="PB779_002582"
     CDS             2996..3667
                     /locus_tag="PB779_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HDE0740074.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRYLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCQCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEKWIAYITLK
                     KRGTI"
     gene            4215..5654
                     /locus_tag="PB779_002583"
                     /pseudo
     CDS             4215..5654
                     /locus_tag="PB779_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            5999..6166
                     /locus_tag="PB779_002584"
     CDS             5999..6166
                     /locus_tag="PB779_002584"
                     /inference="COORDINATES: protein motif:HMM:NF018933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740075.1"
                     /translation="MGSECGHTDGKKSFTIREWTCPICRTHHDRNVNVSINILIKGYV
                     YKHCLRKHQEP"
     gene            6425..6640
                     /locus_tag="PB779_002585"
     CDS             6425..6640
                     /locus_tag="PB779_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740076.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(6828..7115)
                     /locus_tag="PB779_002586"
                     /pseudo
     CDS             complement(6828..7115)
                     /locus_tag="PB779_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2468 a         1090 c         1412 g         2249 t
ORIGIN      
        1 taaaaagatt atttgtgtaa aaaaagatgg cacaagattt tcccaagaat atgacaaact
       61 tatactagct acaggttcaa agcaaattat gttagatgta ccggggaata atttagctaa
      121 tattttttcg ataaagaatt ttccaaatgc taaagagatt tttaaagctt tagatgataa
      181 tactattaaa aaagtaggaa ttattggagc aggatatatt ggagttgaaa ttgctgaagc
      241 cataagaaaa agagggaaag aagtatatct tttcgatgtt gcagatagag tgttgtcgac
      301 ttattacgac cgtagttttt cagataaagt tgaagaaata ctatcaaaaa atggaataca
      361 tctttgtcta tcagaaagtc ctaaaaaata tttaggaaga aaaaagattg aaaaaatagt
      421 cactacaagt ggtacccaat actctatgga tatggtcgta caagctatag gatttctatc
      481 taatagtcca attggcaaaa aggaactctt gagagatgtt agtggagcat atctaactaa
      541 tgaataccag caaacaaata taaaagatat atatgctatt ggggattgtg ctacaacttt
      601 ttttacgtcc attaatagaa gtagtgttga tttttctatt tctaatgctc taagaacagc
      661 ttatattgca actcaacata ttgacaatca agattttaca ccttctggtt cccaatttac
      721 aaatggcttt tctatattta attacaattt ttacgcagca ggtttgaatt taaaaacagc
      781 acgattatta agtgagtcta tagattatat agaaatagaa gatttcatta gacctgtttt
      841 tttgagaaaa aatagtcgtg taaaattaag aattagcttt gaaaaaaata caaagagaat
      901 agtaggtgta caactttgta gtcaagaaga tttatctgga ctattatcaa tgttttctct
      961 tgctatagaa gaacaaatta cattagacaa attgaaaatg ttagattatt tatttcatcc
     1021 tagttttagc caaccctata attttatttt aaaggcagta acaggattaa acattgaaac
     1081 ataatcgtta ctaaatgaaa tcaagaaata tactgtatta ctcaattcat tgaaaatatt
     1141 tatcataatt tttaatagaa aacactatta aagagaaaaa agagaggtaa atcaaatgaa
     1201 aaaatcttta aaacttgcat cagcagttat attaatgtcc caactcttta tagcaacacc
     1261 tttccatgtg ttggcaagcg aaaattcaac atacaaaatt gcaaaagaaa gaaccgagac
     1321 gactgaaatg agtaattccg atgtaacagc agagagtagt gaacttttga caactttatc
     1381 aagtgaaagt agtacgactt caaatgctga gtcttcaaca acttcatcaa gtgaaagtag
     1441 tacgacttca aatgccgagt cttcaacaac ttcgtcaagt gaaagtagta cgacttcaaa
     1501 tgccgagtct tcaacaactt cgtcaagtga aagtagtacg atttcaagtg ccgaatcttc
     1561 aacaacttca agtagtacaa gtgaaataac ttcttcgaaa gtgacaagac caaaccatat
     1621 agagtcttca aaaaaggaag cgccaaaaac ggaaggacaa acaaaaaatt tttcgacacc
     1681 acagcaaata gaatcaacag aatctttcca atcacaacca atactatctg gtaatgaaga
     1741 aattcatttt gacaaaaatg aatctgtaga aaattttatt atgaaaattg gtgagtctgc
     1801 gagaaaaatt ggtcagaaat atgatttata tgcttctgtt atgattgcac aagcgatctt
     1861 agaatctgcc agtggtcaaa gccagttagc tcaggcaccg aattacaatt tatttgggat
     1921 aaaaggaact tataatggaa actttgtcat tatggtaaca aacgaagatt tgggtaatgg
     1981 aacgctttat acgacccaat caaaatttag agtgtatgaa aactatgagg aaagttttga
     2041 agattatgcc aaattattaa ctaagggaat tagtggaaat aaagattttt atgcaggagc
     2101 attaaaagct aatagtaaaa catatcgaga agcaactaaa ttccttacag gacggtatgc
     2161 aacagataca caatactatt tgaagctaaa tgaattaatt aaaacctatg atttaaccaa
     2221 ctatgataaa gaagttaaag gtccacaaat gagtaagact ggataccaag tgcctattca
     2281 taattattca ataaccagtt tgtttggaaa tcgtggaaat gaatttcacc gaggacttga
     2341 tatggcagct acacagggtg agccgattca tgcagttaaa gctggtaagg ttgttaaagc
     2401 agagtttcac tactcttggg gaaattacgt ggtgatacaa cacgaagatg gatcaaccgc
     2461 gttatatgct caccagcaac aatacctagt aaaaactgga gataatgttt tgcaaggaca
     2521 aataattggc tatgtaggaa gtactgggaa tagtactggc ccacaccttc atttggaaat
     2581 ttgcaaagat agtagtcttt ctcagagcat gttagttgat ccgaaaacct tattattcgg
     2641 agactaaaaa aggtaatcaa tctgacaaag taacaagaaa atggttggat tcttagacct
     2701 ttgatcagga tattgagact ggaattgata tctcgattac gatgagtttg acaaataaaa
     2761 caagtccatt atcgaatatc gagtgtatta ttgccgtctt tatgctcata ttttgagcag
     2821 gttttactag atgaaaacaa tttatctatc ttgaggattt cgtgtacgta tcgttcagtc
     2881 ttgtattata aattagtcat aaaatcagac taagaaaaat tgaaaatatt tttttctgat
     2941 ttattaaaag ttaattgaaa ttatatggta cttctttctt gggagggtag gtgcagtgaa
     3001 ggaaagatat ggtcacctta ctgttgttga ggagattact cataatggat ataaaaaata
     3061 tcgttaccta tgtgactgtg ggaatgaaac gattgtatat cgatcaaact tactatcagg
     3121 tagaaccaaa agttgtggat gtggaaatta taaaaatagg cataaatata aaaatttgac
     3181 aaataaaact tttggtaagt tagttgcaat caagccaact aaactgcgaa gtgaaggaac
     3241 tgttgtttgg gaatgtcaat gtctgtgtgg gagaaaaaag ttagtatcgg caaagcgact
     3301 tctaaaaggt gatgtaaaaa gctgtggatg tttgaaatca aaaaagcatc acattgaaaa
     3361 taaaaaattc ggattactta ctgcaaagta tcctttggac aataactgtt catggaaaac
     3421 aaaatgggtt tgtcaatgtg agtgtggcag tatgtgtgag ataagttata gtaacttatt
     3481 ttttggacat actcaaagtt gtggatgttt aaaaaggcaa gaaacaagga catgtgttga
     3541 agggacagta atagagtgtc taacgtcaaa attaccgaaa aataatacaa gtggtgttaa
     3601 gggagtttat cgttctaaag agaaatggat tgcgtatata actttaaaaa aaagaggtac
     3661 tatttaggat cgtatgattc tattaagagt gcagctcaag ttagaaaaga tgctgaaaat
     3721 aaattgtttc aacctttgat tgacaaatat cgaggtaatc attaattatt gtggataata
     3781 attaacagtg atatataaac atctataata tattattcat actattgaca tttagtataa
     3841 tcctatggaa ttgaatatca tagcaatgta tttgaaaagc aaattggaaa acaaataggt
     3901 gcaacaccat aaatatgaaa aaattgggaa aaagtagaat ggaaattttc ttacgtctca
     3961 cgagatagct cacactatta atctgaagaa caatgaagtc gacttttaga aattgctaga
     4021 agaaagtaaa gcgaattatc actagttact atagagtaag ttcaaataaa gcatctcaaa
     4081 cttacatggt tacatgagaa taacaaatcg aaattactca agcttcctat ggctagagtc
     4141 gcgagaagtt gttgggcagt agacataggt tatattgttc ttagctacac gatcattaga
     4201 aaggaaatcc tattatgcat agttatcaag aagatgcaaa agtccaaaaa aatcgctggt
     4261 ggattttgat tgctatatct atgtttacct tcatgtccac attggatggc agtattgtca
     4321 atattgcact acctaccatc tcagatgata tgggcatacc aatgaatcaa gcggaatggg
     4381 tagtgtccgt ttatctgatg attgtctgtt cttgtttgtt gctgtttggt aaaattggcg
     4441 atagctgtgg gaaaatcaaa gtatttcgga ttggtacgct gatctttgtc ttgggctcgc
     4501 tgttgtgtgg gttcaatcat tcgctaggta tttaattgtt cgcacgggtg gtacaagcca
     4561 ttggtgctag tatgactatg gctacaaatg ccggaatcat cacggaagtc tttcccatac
     4621 atgaacgtgg tcgggcattg ggagcaatcg gtgcgcttgt ttcattaggc tcgattgctg
     4681 gaccaggtct tggcggcttg attttgtccc aattttcttg ggcgtacatt ttttggatca
     4741 atgtaccggt gggaatcgta acgatgttga ttgctgaaaa attcttacca aaagatatca
     4801 ccatgagcgg ccatacaatc gatggagggg gctttgctgc cattgcggct acgattatca
     4861 gcctttttgg aacaatcttt ttggggcaag aaagtggctt tttccatcca gtcccccttg
     4921 tactgttcgt aatttcagtg attgcctttg tcagcttttt aaaagttgaa aagaaagcag
     4981 cctctccatt gatttctttc ggtattttta agaacaagat ttttaccatg agcttgatta
     5041 cagccttgtt gattttttct tccaacttct ttgttaatgt agtgattcct ttttatctgc
     5101 aaaatgctcg cgggttgagt cctagctatg ccggactgtt gatgatggtc tttcccttga
     5161 tgatggtcgt cggggcgcct ttaagcggat acctgaccga ccgggttggc ccggagattt
     5221 ttgtattagt aggcttgggt ttattgtcgg taacccaagt catgtatatg tttttgtcag
     5281 tggactctcc tttgtggctg tacattgtcg ctactgccat catgggtgcc ggcaatgcct
     5341 tgttccagtc cccaaataat acgatggtta tgagttctgt cactatcgaa aatttgggac
     5401 tggcaggctc catgaattcc tttgcccgaa atttggggat ggtcatcggg atttcgcttt
     5461 ctacgacggt cttatatcaa gcgatgtctg ctaagatggg ccaacgagta actaactata
     5521 tcgcagatcg gccggatgtc tttttatatg gaatgaagat taccttttta ggcagctttg
     5581 ttttgtgttt tgttgccttt ttcctgacta tctggcgtat caaaaaacaa ggaggtattc
     5641 agaaaaatgt ctgaaaaacc attgttgaag aatttttgga ggcctgcgta tgggtgagtg
     5701 ggatttccat ggatgatgga agatgaagtg aacttctgaa aaccgaaaaa ctcaagtatt
     5761 atcttcaaaa tactagtact caattagatg ctcgatttga ttacaagaag actgcgaaag
     5821 ccactggcaa ccgcaagcta ggtatccacc gatggactac gttttagagg caactggtta
     5881 tgaatacgga gctaacgctc tcatctgcat aagaatgcaa cacccagatt atgtaaagat
     5941 tttcgatact tctgtcaaaa aaatcatcaa gatagataaa tgatttccgt ctagtcaaat
     6001 tggttcagaa tgtggacaca cagatggtaa gaagtcattc acaattcgag aatggacttg
     6061 tcctatttgc cgtacacatc atgatcgaaa cgtcaacgtt agtatcaata ttttgatcaa
     6121 gggctatgta tacaagcatt gccttagaaa acatcaagaa ccttaggaac aacggggata
     6181 gattggttaa taagagatat cgctgttagt aaagacatag gcttgcaagt atactctttt
     6241 atcaagaatt ccgtggcttt agtcatgata ggtttaatac tatgaaaatt ttctttagca
     6301 tttttgattt aggttccttt tctaattata ataaaatgac cactacagta acctactgaa
     6361 atatataaac agccactgta gtaccatttt caaagtagtc tatgagagga gaatcttcat
     6421 tcttatgaac gctggaattg cggatatgaa tttaataaaa aaaaccctta atgattttac
     6481 ttccaattca atatcaaaag gtactggtat caatttaagc acaataaaaa agctgaaaag
     6541 tggtgaaaga tcagtggaaa agctgaatct tttagatgct ataaaaataa cggaatttgc
     6601 tatgaaaaat ggaaaagctg agattgaaat atggagataa ttatcgtcta gtgaactact
     6661 tgccacttag ctgaatttaa cgatccttag tgcttgaagt gggagattct tgggaataga
     6721 gcatacttgc aagcttatgt ctttattaac agcgatatct cttattaacc aagctatccc
     6781 cgtagttcta aggtttttac ttttatctaa gctaatgatc gtattcaaag gaaatttttg
     6841 acccttagaa agtctcattt tatcagacat gagcttaggc attgctgaat tttgttaatt
     6901 cggttttagg ttgtgctttg agcataatat gaaagtagtc tttatcacga tttcactcaa
     6961 ctaaggtaat gtgatgtgat tctgatattc tttcaaagat agttttttgc ataagctaac
     7021 attacatcat caatgagatg tttacaatgt ttcactacta aaataaggtg gtaacaaaga
     7081 agaaataatg aatgattatt tgtatctaat tccatggtat atcaaccatt tcttatatag
     7141 actgattatg acatggatta aaataaaaag gcactatgtc ttaattgtcg gttttcgagt
     7201 taccgaacgg cattcatca
//
LOCUS       DAMEEU010000104         7097 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.107, whole genome shotgun sequence.
ACCESSION   DAMEEU010000104 DAMEEU010000000
VERSION     DAMEEU010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7097
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.107"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..888
                     /locus_tag="PB779_002587"
     CDS             <1..888
                     /locus_tag="PB779_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HDE0740077.1"
                     /translation="RNLDSRTRFEQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYY
                     WVKKLDKPDKYSKIKQEITAIVKESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMG
                     LTCQIRIKRYKSYKGTVGKIAKNVLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPIL
                     DLFNGEIISYSISTSPTYKLIEEMLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLK
                     ENNIIQSMSRKGNCLDNSVIENFFGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKR
                     IKLKLNGLSPVEYRKQSIK"
     gene            1167..1598
                     /locus_tag="PB779_002588"
     CDS             1167..1598
                     /locus_tag="PB779_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009296628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDE0740078.1"
                     /translation="MDAIPRDYEARCMFDAFCKTVLRNEAKSYLAEMKRRRDREVSLS
                     SLSQADLDKLCTVDHYPSDSFTFSSHGYDLHINNELVAEAFAALPSMEQSILILHCVL
                     DMADGEIGGLVGMSRSAVQRHRTNTLSELRKQLKALMPKGG"
     gene            1605..1838
                     /locus_tag="PB779_002589"
     CDS             1605..1838
                     /locus_tag="PB779_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740079.1"
                     /translation="MKNPNYKGIELLPLSVIEAARAGDAGAVERVLQYYSGYMNKLCT
                     RTLYDENGYPHVCLDEAMKRRLEIKLIHAIVTN"
     gene            2262..2462
                     /locus_tag="PB779_002590"
     CDS             2262..2462
                     /locus_tag="PB779_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HDE0740080.1"
                     /translation="MNHDVPIWEKYTLTIEEASKYFRIGENKLRKLAEENPASGWVIM
                     NGNRIQIKRKQFEKIIDTLDTI"
     gene            2546..3739
                     /locus_tag="PB779_002591"
     CDS             2546..3739
                     /locus_tag="PB779_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0740081.1"
                     /translation="MSEKRRDSKNRVLRSGESQRKDGRYAYKYVDTFGKPQFVYSWKL
                     VPTDKTPAGKREDISLREKEKEIQKDLDDGIDTIGKKMTVCQLYAKQIRHRGNVKHNT
                     KLGRERLMRILEQDRLGSCPIDSVKLSDAKEWALRMKEKGLSYKTINNDKRSLKAAFY
                     TAIQDDCIRKNPFDFQLSDVLDDDTEPKVPLTPAQEESFLSFIQGDKVYQKHYDAIVI
                     LLGTGLRISELCGLTDKDLDFENRVIIVSHQLLRNTGVGYYIDEPKTQSGVRKIPMNE
                     EVYQAFQRVIKNRKGAKPFIIDGYANFLFLKQNGYPMTAVDYGGMFGRLVKKYNKSHE
                     EALPKTTTPHAMRHTFCTRLANAGMNPKALQYIMGHSNITMTLNYYAHATFDSARAEM
                     ERLAA"
     gene            complement(4186..4347)
                     /locus_tag="PB779_002592"
     CDS             complement(4186..4347)
                     /locus_tag="PB779_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740082.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(4366..5388)
                     /locus_tag="PB779_002593"
     CDS             complement(4366..5388)
                     /locus_tag="PB779_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HDE0740083.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDR"
     gene            5516..5869
                     /locus_tag="PB779_002594"
     CDS             5516..5869
                     /locus_tag="PB779_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HDE0740084.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            5881..7047
                     /locus_tag="PB779_002595"
     CDS             5881..7047
                     /locus_tag="PB779_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HDE0740085.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
BASE COUNT         2175 a         1403 c         1578 g         1941 t
ORIGIN      
        1 agaaaccttg attcaagaac aagatttgag caagaagaaa tcaaggttaa aacaatcctt
       61 cagctcaaaa aagaatttaa attgaatcta ttactttcaa ttgcacaatt agcgaagtca
      121 acttattatt actgggtaaa aaaattagat aagccagata aatatagcaa gataaagcaa
      181 gaaattacag cgattgtaaa agaatcaaga aactcttatg gttatcgtag agtcacttta
      241 gcgttaaaga tgaaaggata tacaatcaat cataaaacag ttagaaaatt aatgtcccaa
      301 atgggactta cctgtcaaat ccgaataaag cgatataaat cttataaagg aacagtagga
      361 aaaattgcca agaatgtgtt aaaacgaaat ttttcagtag atacacccaa taaaaaatgg
      421 gtgacagacg tcactgaatt caagataaaa ggaagaaaaa tctatctatc tcctatactt
      481 gatttattta acggagaaat aattagttat agtatatcaa ctagtccaac atataaactg
      541 attgaagaaa tgcttcaaca agcaattaaa aaaaagggaa ctgagggttc actgattcta
      601 cattcagatc aaggatggca gtatcagatg ccacaatatc aaaaaaaatt aaaagagaat
      661 aacattattc aaagcatgtc tagaaaagga aattgcttag ataattctgt aatagaaaat
      721 ttttttggtg tgcttaaatc agagtttttt tatcgagaaa aattccgatc aattgagata
      781 tttcaaagta aattaaatga gtatattagg tggtataata acaaaaggat aaaactaaag
      841 ttaaatggac tatctccagt agaatatcgg aaacagtcca ttaaatagtt caacttttgg
      901 ggttcagttc accacagggc tattccggtt atgagtatgt actataccat gtaaatcagc
      961 agcatagcaa agcattttct cgcccggtag gtttgcgacc tgccgggcga tttttgtcgt
     1021 cttttgcggc ccggctgtcc ccaaaaaaat tttttgagaa attttcaaaa aggaggtatt
     1081 tagcgggtag ctggcggcct tgtcaaagtc ttgttagcgg aaagggagag aaccacctaa
     1141 gtcccccaca gaaagggggt gagaagatgg atgctatccc ccgcgactat gaagcgcggt
     1201 gcatgttcga tgctttttgc aagacggtac tgcgtaacga ggccaaaagc tacttggctg
     1261 aaatgaagcg ccgccgtgac cgtgaagtgt cactaagctc tttgtcacag gcagatttgg
     1321 acaagctctg tacagtagat cactacccca gcgacagctt tacgttttcg tcgcatggct
     1381 atgacctaca tatcaacaat gagcttgttg ccgaagcctt tgccgcgctg cccagcatgg
     1441 agcagagtat tttaatcctg cactgtgttc tggatatggc agatggtgag atcggcggcc
     1501 ttgtgggaat gtcccggagt gccgttcagc ggcacaggac aaatacctta tcggagctgc
     1561 ggaaacagct aaaggcgttg atgccgaagg gaggttagac gcggatgaag aacccgaact
     1621 acaagggcat tgagcttttg cccctttcgg tgatcgaggc cgcccgcgct ggggatgccg
     1681 gagccgtaga gcgcgttttg cagtattaca gcggttacat gaacaagctg tgtacccgga
     1741 cgctctatga cgaaaacggc tatccgcatg tgtgtctgga cgaggccatg aagcgccgtc
     1801 tggaaatcaa gctcatccac gctatcgtca cgaactgacg aaccggcccc ggcagcatga
     1861 aacggcttac cctttccccg tttcggtgtt ttcccggtgg cctgatcgca ccttgataaa
     1921 tatgcccgca agataacggc ggcgcatcat agggcatacg gacacattct gtctgtgccg
     1981 agccggacgg ctggtgcgcc atgatacttt tccctacggg aaaagcggag cgaggaacac
     2041 cacgccgcaa tgtgagcgtg gcggcttgcg ggcgacgacg tacaggcagg actatgatac
     2101 tcccttatag ccacagtccg agcgttaaaa gcgtcgcagg caatgggtag ggccgcgtga
     2161 gaaccacgcg ggggtgaaag tcccgtggag ctgtgccagc agccgtccgt ctatgcccct
     2221 aaatcacaca aacctttgaa tttgtgaaag ggggctgcat tatgaaccat gatgtgccta
     2281 tttgggaaaa atacacgctg acgattgagg aagcgtctaa atatttccgt atcggagaaa
     2341 acaaattgcg taagctggcc gaggaaaatc cggcctctgg ctgggtcatt atgaatggca
     2401 accgcatcca gatcaaacgc aagcagtttg agaaaataat tgacactttg gacacaatct
     2461 aatagtgaaa aagggccgca gatatgttat aataatttat aagcatatat gcggctcttt
     2521 ccgtcatgga aaggagcatg acgagatgtc agaaaaaaga cgagacagca aaaatcgcgt
     2581 tttgcggtct ggagagagcc agagaaaaga cggacgatat gcttacaaat atgttgatac
     2641 ctttggaaaa ccgcagtttg tttactcatg gaagttagtg cctacggata agaccccggc
     2701 aggtaaacgg gaggatattt cactccggga aaaggagaaa gaaatccaga aagaccttga
     2761 cgacgggata gacaccatcg gcaagaaaat gaccgtctgc cagctctacg ccaagcagat
     2821 caggcaccgg ggcaatgtga agcacaacac caaactgggc cgggaacggc tgatgcgtat
     2881 tctggaacaa gatcggctgg ggagctgccc gattgacagt gtgaagctgt ccgacgcaaa
     2941 ggaatgggcg cttcggatga aagaaaaggg cctttcttat aagaccatca ataacgacaa
     3001 gcgttccctg aaagcggctt tttacaccgc catacaggac gattgcatcc gaaaaaaccc
     3061 gtttgacttc cagcttagtg acgttctgga cgacgatacg gaaccaaagg tgcctcttac
     3121 accagcacag gaagaaagtt ttctgtcctt tattcaaggt gataaggttt accaaaagca
     3181 ttatgacgca atcgttattc tgctggggac agggcttcgc atttcggaac tgtgcggact
     3241 gacggacaaa gatttggatt ttgaaaaccg ggtaatcatc gtgagccacc agcttttgag
     3301 aaataccggc gtcggttact atattgacga acccaagacc caaagcggcg tcagaaaaat
     3361 ccccatgaat gaggaagtgt atcaggcgtt ccagcgagtg ataaaaaacc gcaaaggtgc
     3421 aaagccgttc attattgacg ggtatgccaa tttcctgttt ctcaaacaga acggctatcc
     3481 catgacggcg gtagattatg gcgggatgtt tggcaggctt gtgaagaagt acaacaagag
     3541 ccatgaagaa gcgttgccga aaacgacgac gccccatgct atgcgtcata cattctgcac
     3601 ccggttagcc aatgcgggaa tgaaccccaa agccttgcag tacattatgg gacattccaa
     3661 tatcaccatg acgctgaact attatgcaca cgccacattc gattccgcaa gggcagaaat
     3721 ggaacggctg gcagcctgac acaaggccgg ttttactact ccatttacta cttttgaggg
     3781 ggaaatggtg agaggtaata agaacatttg taagtatcta acaatatcaa aaatgccgga
     3841 aaagcccgga aacacgggct ataccgacat tcaagaactt ctaaaaagat aatctaaaat
     3901 cccatataat ttttgttgaa aaaataaaag aaatctttga taacaataaa aactagagtt
     3961 atctaatata aatgtaatat tacctttatg atagagtgat caaaatcctt tatgataatg
     4021 acatacctat aaccaacaac aaccttgtac ttactcaaaa tcgagtaaat actccttttc
     4081 cgtcgagtct aaccatctcg gcggtttttt atttgtagaa aagaacatca ggatagacgg
     4141 aaaagtcttg tcctgatgtt cttttcagat agtatggaaa gctgattagt tttctacatt
     4201 ctgtacatat tgttcaaagt agttctgtaa atcggctttg agtttctgat attcctcttc
     4261 gctatactct ttatcttcga ttttcccatc aaagaaagga atatttagtt cttcccgtag
     4321 tctgtctaat acgtcttgct gattcatttc attctccttt tcttactaac gatcaaaata
     4381 aacacagaca cattctggta catagacatc ttttttcagt aattccagta atcctgtttc
     4441 aggatgacgg cgatataatg tcagattatc ggtgttctga ttggcacaca cgacaaaatt
     4501 attgcttgga tctagtgcga aatcgcgggg aaaatcccct tctgttgaga tgatttgctt
     4561 gttttgaatg tgggaaccat cttcaaaaac tgcgaataca gcaatcgagt tatgtcctcg
     4621 gttagaagca taaaggaact tgccatcatt tgaaatgcgg atagctgccc ctccattttc
     4681 accgtcgaat tcttctggca aggtcgatat tttctgtaat tcttcaaaag cacctgtttc
     4741 tttattataa gaaagcacgc ggactgtgct gtctaattca ccaaataaat aagcgaattg
     4801 tccatttgga tgaaagacaa gatggcgagg gcctgttcct ggctctgcag tgaaggtagt
     4861 tacaagattc aatttgccgt tttcggacac atcataagta tacacacgat ctgtaccaag
     4921 atcacatacg actaatcgtt ggtcaggagt cagatccgta tagtggacat gcgcatgatc
     4981 ttggttttta tgaggacctg tcgcttcttg atggaatatt gaatctgctg ctttcagttc
     5041 gccatctcct aatatatggt agacatttac ttcaccttta tgatagttcg ccccgtatag
     5101 taattgacgt gcttcatcaa ccgctacata acacaaagga gcgccagact ctgttaccgc
     5161 attcaaaaaa tgaaaatcct tatcgtacgc accggcacca cctaatccat ccacactagt
     5221 aactgtgtaa agattgccag ctttactttt tgctacatag gtagggctat tttcttcaac
     5281 agctaatgaa aggttggcta attcttcttt ttctgtatca aggtcgatcg tatagattcc
     5341 tttactttcg cgacgcgtat aggttcctaa aattatcttt tcgatcatat gagctgattc
     5401 ctcctaattg taatgaaata gttttcgttt ttattctatc acataattat tccacacggc
     5461 taaagaatga gaatgtgtta tactgttttt gaaagcaatt aaaggagaga gtgcaatgat
     5521 tcaggcaaag attacagaaa ttgggacaga agcaataaac aaggaagaac ccatgctgat
     5581 tttgttcgat aaaacagcaa cagctgcctt acgaaaatat tcggtgattc aagaagtatc
     5641 aaaagacgaa cctttttctt tgaaagcagg cggaacaatt gcttttgatg atcaggtata
     5701 tacgatcgat tatgtcggtc cgatggccaa tgggaattta aagacagtag ctcacgtatc
     5761 attgattttt gatgcttgtc cagaagaagg acaaattgca aatggaatct atcttcatcc
     5821 gcatagactg cctgctattg gtttgggaag ccaaattttt tataactaac aggaggaatt
     5881 atggaaggaa aaaataagaa gaacagaccg gtatcgtggt tttggcgctg gtttttaaat
     5941 aatcaagtag tcacagcctt acttgttgta ttgttaatat tgctgatcgt ctttttattt
     6001 acaaaagttt catatttgtt tgcaccaatc tggcaatttt tagcaatcgt aggtctgcct
     6061 atcattttag caggaatctt gtattacttg atgaatccgg tagttgatta ctttgaaaag
     6121 cgaaaagtac caaggcttta cagtatcatt gggctgtttg ttttggttgt tgcactaatc
     6181 gcatggggga gcgtagtgat catccctaag attcaggaac aaacagtgag cttcatcagt
     6241 aacttccctc aatatgtaga tacgattgat aataaattaa ccgagatttt gcgggacccg
     6301 ctgttcaacc aatttcgcga acagttggaa acagcaggtg ataagttcat gaattcggca
     6361 ggcgatatga tccaagatat atctaagagt acagttcaga gtcttggaag ttttgtcggc
     6421 gcggtagcga ctattttagt ggctctgctg acgatgccgt ttatcttatt ttatctattg
     6481 aaagacggta aacaattagc accttatttt gtcaaatttt taccgacacg catgcaaaaa
     6541 ccgacgttga atgtgctgag tgaaatgaat agtcaagttt cttcttatat aagaggacaa
     6601 ctaactgtgg cttttgctgt ggcaatcatg tttatgattg gttttgcggt cattggttta
     6661 gagtatgctg tcacgttggg gattattgcg ggttttttaa acctgatccc ttacttagga
     6721 tcatttttag cgatgattcc ggctatcttt ttagccattg tagcaggtcc attcatgatc
     6781 atcaaagtac tgatcgtttt tgcagtagag cagacaatag aaggacgctt gatctctcca
     6841 ttagtactag ggaatcagtt agcaatccat ccagtaacga ttttattagt tctgctgact
     6901 tctgggaaat tgttcggaat catcggtgtg atcttgggga ttcctgttta tgcagcagct
     6961 aaagtagtga ttactcatgt ttttgaatgg tacacaacaa tctcttctct ttatgaagaa
     7021 aatccgttga aaaagcagaa agaataacaa aaagagacag atgggaaaat atccaaggca
     7081 caaatgctgc tttgaag
//
LOCUS       DAMEEU010000105         7077 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.108, whole genome shotgun sequence.
ACCESSION   DAMEEU010000105 DAMEEU010000000
VERSION     DAMEEU010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7077)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7077)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7077
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.108"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            581..967
                     /locus_tag="PB779_002596"
     CDS             581..967
                     /locus_tag="PB779_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDE0740086.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFNKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            1065..1256
                     /locus_tag="PB779_002597"
     CDS             1065..1256
                     /locus_tag="PB779_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740087.1"
                     /translation="MNTLKEDFILAKNGNEEAVVAILKRFSALVHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            1770..2102
                     /locus_tag="PB779_002598"
     CDS             1770..2102
                     /locus_tag="PB779_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740088.1"
                     /translation="MKKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            2012..2215
                     /locus_tag="PB779_002599"
     CDS             2012..2215
                     /locus_tag="PB779_002599"
                     /inference="COORDINATES: protein motif:HMM:NF024673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDE0740089.1"
                     /translation="MFYEHKDRYGSPGITQKLYDEGIEINKRVVAVLMREMNLCTRGF
                     HRRKSSHGREKTIKEMVKKMLNR"
     gene            2399..2554
                     /locus_tag="PB779_002600"
     CDS             2399..2554
                     /locus_tag="PB779_002600"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HDE0740090.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLTDHHITHSMSQTGTPVDNAVIE
                     AFHRSIK"
     gene            2830..4170
                     /locus_tag="PB779_002601"
     CDS             2830..4170
                     /locus_tag="PB779_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDE0740091.1"
                     /translation="MSYSEFTKELLDILDLNLTFHEDAFRKERINDETCFVFDGTLTY
                     QPEECFHCHYQNKQTIIKWGWKKVSILLNDVSNYKTIVRINKQRFKCKHCGKTFLAED
                     SVSDRRCSIARRVKQAILELLSEPISMSLIARMKHISPTTVIRILRSLRPKTVSLNQP
                     LPEVVCFDEFKSVKNVSGAMSFVMMDGKTHQLIDIVENRQLNPLRDYFLRYPRKVREQ
                     VRLVVSDFYTPYRTLVKECFPNARIVADRFHISQHIGRAFTNHRIQVMKTFKKGDRRS
                     KHLKKYWRLLQKNAWELNGQHRYWRPSFRDHLTEAEIVDRLLYYDDSLKRGYEVYQVF
                     LSAIRRQDVPEFVALLKEDYKELPEHYQPVFTTFKKYRTEIKRALRVPYSNGPIECLN
                     NHIKVLKRIAYGFRNFQNYRERIFLYRGKYFKKTKNTTQLTKARTTTRLDKIAV"
     gene            complement(4248..6287)
                     /locus_tag="PB779_002602"
     CDS             complement(4248..6287)
                     /locus_tag="PB779_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HDE0740092.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKIITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSFQTTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLINPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLLAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(6345..7067)
                     /locus_tag="PB779_002603"
     CDS             complement(6345..7067)
                     /locus_tag="PB779_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HDE0740093.1"
                     /translation="MLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEPKSIPTTLNVAL
                     IGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGMNKINAAYSYGG
                     VDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSLDLDGVYINKGE
                     QVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFKLPKAVGKLLGS
                     IQTNLPESVLLDCGMDFLKDIC"
BASE COUNT         2186 a         1392 c         1229 g         2270 t
ORIGIN      
        1 cgctttcatg tatattccac cgtaaaaagt acattttatc accgagaact catcattttt
       61 catcatgatg aatactattt acatatatct agttcaaaga caataattat tatgatccgt
      121 tattatctaa gcactataca gataatagga atttttcgtt tctaaatact ccaatttggg
      181 aatccaataa aaattttcgt tcaaatacgt gtctattcga actcttttct agttgttaat
      241 tatgaagggg gaagaaataa aaaatacaat ctatacacga ataagaatat tatccaaaag
      301 gaggttttag aaaagattta ttatacgtaa aaagctcaag acattttctt agccataagg
      361 acatgtttga tatttaagaa gatatatgaa ttttcttttc taagtataaa gataactatc
      421 cattatcaac taaaaaaaca tttttgaaaa taaacatcag cagtcctatc aatgcatgtg
      481 agcttataga agttattcgc agcgcagcat aattgcatta gcttcttttc gtgttttttg
      541 cctcttttcc ctttaaatct taatggagga ggtgtgcaat atgtcagata acgacgaacg
      601 cgtaaatgcc cagttgattc gattctttga aaaggtcatt ttgaacaccg ctaatactta
      661 ttataaaaaa caagaagaaa ttcaaaaaca tgaacaactt gatcaactcc caccatattt
      721 gtttactaaa gatactataa aatttaaaca accgattaat gttttaaatg tgactctcct
      781 tgttgaagat ataaaattag caaaaatcct tcctttgttg aaagaacctg aacaaatttt
      841 tcttatcgaa aaatttatct ttaataaaac tgataaagaa attggaaagg ttctgggtat
      901 tacaagacag ggtgcgacaa atttaaaaca tcgactttac aaaaaaattc aaaaaatgct
      961 ggtttaatat ctgcataata actaattttg tatgcttctt tgctcgtcct cctccttccc
     1021 caaaaaataa atagattata agttcatggg aagaaggtaa atttatgaat actttaaaag
     1081 aagatttcat tttagcaaag aatggaaatg aagaagcagt tgtggccatt ctcaaaagat
     1141 ttagcgcttt ggtccataag caatcctgga gaactggaaa atatgatcaa gattgttatc
     1201 aagaatgtat gcttgcaata tatctagcta tctcgaaatt cgaaattaaa gaataactca
     1261 actaagggag tctgtgacat aagtaaaaag atagtttcaa atttcgaaca ataaatttga
     1321 agccatcttc tttataatta taaagtatcg attttacagc gttctataat gattcataga
     1381 atctaaaacg aatgatttta attattaacg ttttttaatt cgtttttagc ttaaaaataa
     1441 cttttgtcac agtctcactc ctaaaattac tttatttacg tacgaagtgg gcaggaggtc
     1501 gaatccagaa ctgggccatg gtacttcaac gaggacttct cctctagaat tgaaaagcat
     1561 gcgatttacc ttccgtaacg acggtagatt tattcaacta tgtgtccaat caaaatttgt
     1621 ctgatttcaa aaatagtcaa gagaattttg gttgttaaaa actcttatct atcaacttcc
     1681 acagtttagt tgacaaaccc tgatactaag ttgggctatg atacactttt cttgactatc
     1741 agttacgtta ccggaaggaa tgaactctat tgaaaaaaac atatgatcgt aaatttaaac
     1801 taaagatttc acaggatatc cttgagaaaa aagtaactac caagaaaatt gctgaagaat
     1861 acaatatctc tcgtccaaca atttcccgat gggtttcaga atatcgtcga tacgggaaaa
     1921 atgcttttgc tggacaagga aaaagattac ctgataaagc agatttctac attcttgaac
     1981 aggaaaataa acgactaaaa gaggaagacg agtgttctac gaacacaaag atcgatacgg
     2041 atctccaggg atcactcaaa aactttacga tgaaggaatc gaaatcaata aacgtgttgt
     2101 agctgttctt atgcgtgaaa tgaatttatg cacaagagga tttcatcgac gcaaatcttc
     2161 tcatggtaga gaaaaaacaa tcaaagaaat ggtaaaaaaa atgttgaatc gataatttga
     2221 acagaaccaa attgatgctg tttgggtgac ggatattact tacattccat gtaatgacgg
     2281 tcgcctctat ttgtccacct atattgactt agcaactcgt attctacgtt actatatggt
     2341 ggattcacac atgaaaaaag agattgtcgt ccgtccatta caaatttatt aaggagaatt
     2401 gcctacggta attcattccg atagaggtag ccagcatcgg tcttttattt atcaagagct
     2461 gttgaccgac caccacatca cacattcaat gagccaaact gggactcctg ttgacaatgc
     2521 agtaattgaa gcgtttcatc gatcaatcaa atgagaatta atcgactcca acaaatataa
     2581 aagtaaaata gagatgaagg tgttaatcca agattattta gaagactact acccaaacaa
     2641 aagaatccat acaaaattta tgatgactcc ttgacaattt gaagcgaaga aaataaggga
     2701 tctataatat ctagtgttgg tgacgccttc tgttgccaat actttttctt ttttctaata
     2761 aacgcaaaca gacaccttga aatcctttag aataaagtcg acgaaaacca ttcaaaggag
     2821 tgtttcaaga tgtcctattc agagtttacc aaagagttac tagatattct agacctaaat
     2881 cttacctttc atgaagatgc ctttcgcaaa gagcgcatta atgacgaaac atgttttgtt
     2941 tttgatggca cattgaccta tcaaccagag gaatgcttcc attgccacta tcaaaataag
     3001 caaacgatca ttaaatgggg ctggaaaaaa gtatccatct tattgaatga tgtcagtaac
     3061 tacaagacca ttgtgcggat taacaaacag cgcttcaaat gtaaacactg tggaaagact
     3121 tttttagcag aagattcagt tagcgatcgt cgctgctcca ttgcccgcag agtcaaacaa
     3181 gccattcttg agctattaag tgagcctatt tctatgtctt tgattgcacg tatgaagcac
     3241 atttctccga ccactgtcat tcgaatactt cgcagccttc ggcctaaaac cgtttctttg
     3301 aaccagccgt taccagaagt ggtgtgtttc gatgaattca aatcggtgaa aaacgtctcg
     3361 ggagccatga gctttgtcat gatggacggc aagacccatc aactgattga tattgtggaa
     3421 aatcggcaac tcaatccttt acgcgactat ttcttgcgct accctagaaa agtccgtgaa
     3481 caagtacgtc tagtggtttc agatttctat acaccctatc gcacattggt gaaagagtgt
     3541 tttccgaatg cccgaatcgt cgccgatcgc tttcatatta gccaacacat cggtcgggcc
     3601 tttaccaacc accgaattca agtaatgaag acctttaaaa aaggggatcg tcggtcgaag
     3661 cacttaaaga aatactggag actacttcaa aagaatgcgt gggaattgaa tggtcagcat
     3721 cgctactggc gtccgtcatt tcgagatcat ctgacagaag cggagatagt cgatcggcta
     3781 ttatattatg atgactcctt aaagcgaggc tacgaagtct accaggtttt tctttccgct
     3841 atcagaagac aagatgttcc tgaattcgtc gcgctcctaa aagaagacta caaggagttg
     3901 ccagagcact atcaaccagt gttcacgacc ttcaagaaat atcgaacaga aatcaaacga
     3961 gcgttgcgag ttccctattc caacggccct atagaatgtt tgaacaacca tatcaaagta
     4021 ctaaaacgaa ttgcctatgg ctttagaaac tttcaaaact accgagaacg aatcttttta
     4081 tatcgaggaa aatatttcaa gaaaactaag aacactaccc aactgactaa agccagaaca
     4141 acaacacggc tagacaagat agctgtctag ccgtgtgagt atctcgatta ttctattgaa
     4201 tttcttcacc aacactcatt gacgaagagc ccttaaaaag caatttttta ttgataattt
     4261 tggttgaggt attgcaatag ttccgatgct cgtttggttg ctgaatcatc atcttcttta
     4321 ttttccaaca tgctgaccat catataacct tggttatcaa gattgaaagc aagcaagaaa
     4381 ctgttctctt gcccctttac atcctgtttt tctttgattt ccgctgtacc agttttcgct
     4441 gccaacggaa tccctaaagc agaaagagaa tgtgctgtac catttacatc ttgcacaact
     4501 tctctcagat ctggcacgat cgtttgtact gctgtttcgc tgatgacatt cttcttatct
     4561 tttgtctctt tatctgcaat caatttagga tagacaagtg tgccattgtt ggtaaaaaca
     4621 gaatacattg ctgcttgctg gataggatta attagaagtt cgccctgtcc atatccagta
     4681 tcagctagca agatatctga gttaaagcta tcttcattag aaatttgtgc tggattcata
     4741 ctaattggca aatcaaggtc ttcaccaaaa atgaatttat ctaagcctgt acgaaatttt
     4801 ttctcaccca ttttcaacgt ttcttgtgcc gcatatatat tatcggaata gatcaaagca
     4861 gtttttaagt ctacttgtga tacatcacta ctgacacgcg ttgtttgaaa agatccccaa
     4921 gaactgtctt tttgccattt aagcccgttg atcgtcaaca cttcatttgg atcgatagtg
     4981 ccgttgtcga gaccgattgc tgctgtaatt attttaaacg tagatccagg agcataacct
     5041 gtcgcaaatc ggctgatgaa tggatgttca ggattttctt cataagcttt gtaatcttct
     5101 tgtgagatcc cgtttgtcat tttgtttgga tcatagcttg gagagctagc aagcgcaaga
     5161 agatcaccgg tttttggcgt tgtcgcaaca gttgatccag cttttcctcc tagactgtca
     5221 aaagctgttt tttgtgcctt cgcatcgatt gtcaatttga tatctttgcc attttgaact
     5281 tcatgttcga tcagaacttt tttctctaca ccgtctgcat ctgtaatgct taatttccca
     5341 cctgttgtcc cacgaagatc cttatcaaaa gccatctcca aacctgagcg accgattttt
     5401 ccattactgc ttaattctgg attcttatca atatcttctg ctgtgatatc tcccacgtaa
     5461 ccaatcagct gagcagctgc ttcacccaaa ggataatatc tgccgtctac ttcttgaatg
     5521 gtagctccag ctggaagttc tggcgttgct ccatcaatga ttttcaatgg gacaaagtaa
     5581 tcgggttgta cccagctttg tgaaatcgcc tgattgatag catcttctgt taagtcgaag
     5641 gaggaagcaa tcgctttgat attggctgtt ttttcgcctc catctccaag tttacttgga
     5701 acgactccta attgttttag tttgcctgtt gttgctaatg gttcaccatt tcgatctata
     5761 atattccctc ttgctgcttc ttgtgtggtc aggcttactt tgtcatttcc ttccatttct
     5821 ggaaaaacca agttgggttg ccagttgatc gtggtttgac catcatttct gtctaatgtt
     5881 cctttataag aaagatcttt caattcacct aatgaggtat tcatctttgc tttatatgaa
     5941 aaactgtaag tagaatcgtc ttttttatct acttttagat tcgatatctg aagtcctttg
     6001 acatcagcag caccgtatat attctggtat ttatctaaga tctctttttc agataatgca
     6061 cttttatttg ccgccttttt tgatgtcatt tctgcagctt tgttataatc tcccttgttc
     6121 aaagcttgga caaattgctc aactgtcttt tctccagctt ctactgcttg ggtttcttga
     6181 tagtgctggt agtaaaaata accgccaccc gcagctgcta ttaagatcac tgcgccggca
     6241 atataagcgc ctgttcgatt tttgccgtgc ttgtcacttc ttttcatttt ttcctccttc
     6301 tcttgcttgt cattccttta tttcactatt tatacctgtt tattctaaca tatgtctttg
     6361 aggaaatcca taccacaatc cagaagcaca ctttctggaa ggttcgtttg gatactacca
     6421 agtaatttcc caaccgcttt gggtagcttg aatattgaag ttacgtcttt cagctgctga
     6481 gagatagctt tgatcacttg ctgctgcctt ctgatcctcc cgaagtctcc ttctttgtct
     6541 tcccgaaatc gagcatactg gagtaaagta ttaccatcca tcacttgctc tcctttgttt
     6601 atatatacgc catctaaatc tagagatttt tctgcatcga tcttgactcc accaggaaac
     6661 agttcattaa cgcaatcgat aaaatcttga aatgtgatac ttgcataata gggagcttca
     6721 aatttgaaat tttcctttaa tgtttgattt aataaatcaa ctcccccata agagtaagct
     6781 gcatttatct tattcattcc gtaacctgga atatcgacat atgaatctct catgatagag
     6841 atcagttttg cttgttgtgt tttctggttg tattgtgcaa ccagaagtga atccgagcga
     6901 ccgttttcgt ctttcgaacg agcatctgaa ccaatcaaag ccacatttag tgtggtaggg
     6961 atacttttcg gctctacctt tttcacagtt gaactctgtt ttgcagacga aaatccatgg
     7021 ataaactcaa tcgaaaaata gccaactact aatgtaagca gtaacaaaat agataat
//
LOCUS       DAMEEU010000106         7019 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.110, whole genome shotgun sequence.
ACCESSION   DAMEEU010000106 DAMEEU010000000
VERSION     DAMEEU010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.110"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..813
                     /locus_tag="PB779_002604"
     CDS             <1..813
                     /locus_tag="PB779_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HDE0740094.1"
                     /translation="KKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSD
                     NGQIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAIKRVKSVSSG
                     DNFIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIES
                     KSLNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHAL
                     ALFGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            807..1229
                     /locus_tag="PB779_002605"
     CDS             807..1229
                     /locus_tag="PB779_002605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740095.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            1531..1911
                     /locus_tag="PB779_002606"
     CDS             1531..1911
                     /locus_tag="PB779_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HDE0740096.1"
                     /translation="MSEQNQNLASDHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            1893..2807
                     /locus_tag="PB779_002607"
     CDS             1893..2807
                     /locus_tag="PB779_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDE0740097.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            3052..3741
                     /locus_tag="PB779_002608"
     CDS             3052..3741
                     /locus_tag="PB779_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740098.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(3862..3948)
                     /locus_tag="PB779_002609"
     CDS             complement(3862..3948)
                     /locus_tag="PB779_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDE0740099.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            4585..5529
                     /locus_tag="PB779_002610"
     CDS             4585..5529
                     /locus_tag="PB779_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HDE0740100.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
     gene            5550..6083
                     /locus_tag="PB779_002611"
     CDS             5550..6083
                     /locus_tag="PB779_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HDE0740101.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            6098..6268
                     /locus_tag="PB779_002612"
     CDS             6098..6268
                     /locus_tag="PB779_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740102.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            6678..>7019
                     /locus_tag="PB779_002613"
     CDS             6678..>7019
                     /locus_tag="PB779_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HDE0740103.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTV"
BASE COUNT         2668 a         1222 c         1230 g         1899 t
ORIGIN      
        1 aaaaaaaata caaatggaga atattcagga agtatttcac aatttttagc aaaagaactt
       61 caaaatctag tagatagtaa tataacagat acaaccttat tttttcaaga taatagcatt
      121 tattattccg ataatggaca aattaaacta ctttggaaat cacctttaag tacagaaaaa
      181 aatggtgttt cttcctttac agaaaaaaat gatcttatat ccgtaaatat aaaaaataaa
      241 attaaaaatt tctctaaaaa acaaaatttt cctgcgatta aacgtgtaaa aagtgtctcc
      301 tccggagata actttattat gattaattgg cgtatagcag aaacccaaac aagttttccg
      361 tggtgtgctg cttacgtaga agctgctatc ttatgtaaca aaacagatgt acatgctact
      421 tcagctagag ccattatgca ttatacctat cctaatttaa acaacagtca aattgaatca
      481 aaaagtctta atcaagatca aataataaaa tatgcaaatt actgtggtgt ttatcctaaa
      541 aaagtagcac gaatactaaa cctttcagag gtccaaacac aactaagaaa aggaaatgcc
      601 atttatatgg gaactgctgg ttatggaaat tatagtaaca gccgtcatgc acttgcatta
      661 tttgggtggg tcaatcaagg tggttatcaa acttactatg tgtggaatcc ttggtataac
      721 tacccaactg taataagtgc aaatgcagga ccagttacaa ttcctgtacc tggaggtggt
      781 tttacttggg acaataccat tacaaattgg taaataaacc cattgcttta gttatgggtc
      841 tagtgttagt tcttttctta actagttgtt caaaaaaaca agaaatacaa aagactgatc
      901 tgattccttt tctaggaact tggcaaacta aagatcattc agaacgtcta gtaatcacta
      961 atttaaatac ttcaaaaaat atagaacaat ataccatctt agtaaaagag aacaatcata
     1021 aaattcaaat cattgataaa aatttaaata taaatgaaca agttttcatt tacaaagcaa
     1081 caaataattt actaacactg cgctctaata aaaaacaatt agattacact tttagtttgg
     1141 attctccaaa aaagctcgta tttattttga caacgaatga tgggacagaa gggacagcta
     1201 aaccaattga attttttaaa gctgattgat gaatagttgt ttgatattac aaaacaataa
     1261 tttcaccgaa ggtgaaacaa gcgaaacttt acaaaaagtg gctagcattt gctagccttt
     1321 tttgtattgt ggagcgtggg ttttgagggg gattcaaggg ggagcttgcg cccctttgaa
     1381 aagcggttat ttgcaccaaa tacgtaggta tttggctagc aaatatagag cttgccaaac
     1441 ccttttagtg agctttactc attgtacctt tttaggtaca atggtattgc gaacgatacg
     1501 tccgtaggac gtactgaaag ggtgggactt atgagcgaac aaaatcaaaa tttggctagc
     1561 gatcattcta aaaaatatac ctatcgatcc gagccaaaac aaatcagttt tcgagtgagc
     1621 gaatctgaat ttgcaaagct gaagcagtca gctgaagctt tgcaaatgag tgtgccggct
     1681 ttcgtaaaag ccaaggcaca aaacgcgcgt ctggtgacac cgaaagtggc gccagacatt
     1741 gcccaggcaa tcgcgcgcga tttagccaaa gctggaggga atatcaatca aattgctaag
     1801 tggtgtaata cacaccaaca cgacgttgct cctggagacg cccaacgctt atccgaaaac
     1861 ctaaaaatca tgcaaaagga gctacaaaag atatggcaac agttaaagta agccgaacca
     1921 cttcttgtag tcgtgcaatt aattacgctg aaccacgagc aaccgtcaaa acagggataa
     1981 actgtgacat tgattatgcc aaaagcgaaa tgaaacaaat tcgcatgctg tatggaaaag
     2041 acgatcgtgt acaagcacac ttattgatcc agtcttttcg accaggagaa attaccgctg
     2101 aaaaagccaa tcaactaggg gcagagtatg cgaaaaaaat agcccctgac caccaaatcg
     2161 cgatttacac acatacagac aaagaccata ttcataacca cattgtcatt aactccgtca
     2221 atctggaaac tgggaacaaa tttcaagccc atggtcaagc atttttaaac aaatgttatg
     2281 acctaaatga cgagatttgt cttgaacatg acttaacaat cactgaacga gggaagaaac
     2341 ccgaaaaacg aaccatgtct gaaatcaaat taaaagaaaa aaatgaacct gtttggaaag
     2401 acgaaattcg gtttgcgatt gatcaaacaa tgaaaaacaa aaaaactcga acgtataacc
     2461 aattttgtga ttctcttaaa acattcggca ttcattgctt gaatcgtggg aaaaatttta
     2521 cttacgaatt gatccacaaa aagaaaaaag tacgatccaa caaactagga aaggattacg
     2581 aaaaggagac gattttacat gagctggaca gacgagaacg agcctacaat caacaacgaa
     2641 ccaacgagct acgaagagct cgagctagca ttcgcgaaac tgcaaaagaa gtacgaagag
     2701 aacaacgaac tcttacgact gaacaaccgg aaattagacc gactcgaaga aaccatgacc
     2761 aacacgttga aagaggagca gactaccaac aagaattatc gttctaaaac gttacaagac
     2821 atagaaaatg aaataaagaa acaacgtgct tttcttgcac cttataccaa agaaagaata
     2881 caaactacaa ttgattcaca agtcaaaaaa ttccaccatg cgctattaaa ccagcgaaat
     2941 aaagaacaga aaaaagtaat tatgcagcga tcaatggata ttcttgcccc cttatgttgc
     3001 ttaatcatga cactgttagc cttttggctg gtatggggag aataaataga aatggcattc
     3061 tatttaccct atctactcat ttttgccagt attttaggaa ttatttggct tagctataag
     3121 gcttatcaaa caagatattc attaaaaggc tctaaaattc gatttaagag gtttttattg
     3181 ccaggggtta tatttacatt atcaatcgtt ttaagtggtt tattcggcgt tttagaggga
     3241 aataaacgta tttcaagaag tattttatta ggggatatca ctcaaaagta tgaagcagca
     3301 tgtgataaaa agaaaaagga gcaagtgtta acacaaaaaa tggaagagtt taccacttgt
     3361 tatgaggaaa tgaacgatat ttttgtgaat caagaaaaac gtttgacgga taaaaacatg
     3421 gaaaaactca ctcgtcttta tcaaaacttg ccagaaaaac agcaaaaaga ggttcaagac
     3481 aactatgagc gaaccaaaaa agacgtgcaa tattttaaag atacgcagac agaagaagct
     3541 tgttataatt tattcagtga tacaatccct ttttcaacta gtgaacagga acgaaaagaa
     3601 cggcaacaat cagttaccta cgaacgttat aaagcactgc ttcagcaagc aacgaacata
     3661 caaaatccaa cgaaaaaaga aacggcatta aattatctaa aaagtgtcaa ggaatggtta
     3721 gatcagcaac agcaaaattg aatttgatcg gcaatcatgt taaactaaac atgcaaatga
     3781 tcaaacatta gatacacgaa agccccagag aggtcggatt ctctggggct ttttttcagg
     3841 ttgatgtcgc ctttattgat tttacttctt gtttcggtta ttcaaccaat aactgaataa
     3901 agagacacaa acttctataa gaagggggca aatgaacaat tcaaacatta gatacacctc
     3961 cttccagtcg caagactgtc ggataggcga caagttatta tatcttaaaa aattaaactt
     4021 gtgtggtgtt tttaagtatc gcttatttta gggttgttag ggcttgccct gaccgcctgt
     4081 aaggcgcttt aaagctagat aaggattttt atccaagact gtcttaaaac ggcttagata
     4141 agcattcaga accgctcaaa ggcctcttta ccaacatgtt tttagcaaag gagcctttag
     4201 gcgactgcgc agtacaatgt gagagcgtag cgatcacacc tttttggcga ccgtaggaag
     4261 caaggttttg gattggcagt tttgaaaaat gcgcgaacct gtttaaagaa aaaagaagtg
     4321 gtttttaggc gggaaaatta gcccccctct ttttatatct ctttttaaac ctctttttaa
     4381 acctctttac cgtaagctgt gtccttactc taccaatgga tacagaatgt tatgaaggac
     4441 attttgtctg tttatgaagg acattttgtc tgtttatgaa ggacattttg tctgtttatg
     4501 aaggacattt tgtctgtttg aacgtcaaat atgaatgtct tgacatttaa aaaatgtcat
     4561 tcataattgg attgaggtga ttatatggct aatgagattg taaaatacca ccatgaatta
     4621 aatacaattc ctttaagaaa atttacaccg gttgaaatga atttgttttt ttccatcgtg
     4681 tctagaatgc gtgaaaaagg ggataagaca gttcgtttta cgtttgacca actaaaagat
     4741 ttaagtaact acaaagcaac tgcaaatgta cgatttgtag aagatttaaa agcaacttat
     4801 gaaaaaatct tatctttacg ctttggtcgt agaagtgagt ctgggctttc ttacgatatg
     4861 tttgtaatgt ttacagaatt taaaatcaac ggggacgtag aaaatcctta cgtagatata
     4921 cgaatttacg aaaaagcact gcctttgtta aataatttag acgagtgggt acgctattct
     4981 ttacaacaat tcaacgagct acaaagtggc tatgcaaaga ctatgtttcg tctgttaaag
     5041 caatacagaa ccaaaggttt cgcatatttc tccaaagaag actttcttga attattagat
     5101 attcctaaaa gttataagca acctgatata gataaacgag ttataaaacc tatacgtcaa
     5161 gaactaactg caatcttcaa aggactaaca atcaaaaaga aatacggaaa aggacgggga
     5221 aaacctgtta ttggctatca atttacgttc aaacctgaga tcaaaaaagc agacgacttt
     5281 aacaaacatg caccaaccaa agaagaccaa aataaagcat tggctttagc tgataaacaa
     5341 aaagaatacg aagaacccgc tacaacaatt aacgaaaaaa tcaaacagaa gaaacgagaa
     5401 cttgaactcc tccaacaaat caaacaacta gaaaaagaga aaaaagctct tgaaaaacaa
     5461 acagagtccg cactttcgga aaaagagaaa aaaagtttat tatctgattt agataattta
     5521 ttccagtagc aacctaggag gcaaccagta tgcaaccaca agaaaccttt acaataaagg
     5581 aattgtcaga tctttttaag atgagtaggc aagcaatatc gaaacatatc caaaaattag
     5641 attcttccat gatagctaaa aatgagcgtg gttataaggt tgtattgcgt tctggagtat
     5701 tgcaacttgc tcgcaactta gacaatcaaa ggttgctaga taagttgcat aaacatgaac
     5761 aaaacaacga taaaaatgct tatataccaa acaaaaacgt ggttgcaaac aagttgctag
     5821 atcagttgcg tgaagaaaat gaatttttac gagaacaact tgccctcaaa gagcaaaata
     5881 attctcatat acaaaaacta ctcgaccagc aacaacaact caccctgcaa gccaaccaac
     5941 aaatcgaaaa acttcaggag caactgcagt tgacttatac ggaagagtct tcagagaata
     6001 gttcaacgac tctttctgaa gcaacagaaa caatggacga acaaacaaag aattggaaaa
     6061 aatggtggca gctatggaaa tgaagaagga aatacttatg acaaaaaaac acttgctatt
     6121 cggttctatc ctactaggaa tattaagctt tagcccaatg ttattatcag tggccaacaa
     6181 aggaaataaa aaaggggaac taaaactcaa tcctaattac tacaacagtc aaaatgagga
     6241 agtatttgta gaaaaacttg ataaataaga aaagactgct cgtacgagca gtctttctga
     6301 aagagattat cctattatta accttagaaa agaataataa atgaatatga gatatgtaaa
     6361 aagcataaca aacacaaaca aaaataacaa gtatttaaaa aatgaccgat caatattcac
     6421 aaagaattag aaagaaacaa ccgcagaaaa ccaagcctta aaaagagctt ttaacctaga
     6481 ccaataaaaa ttcacaaaat cagcgcctgg atcccttggt acaggcgtta cttggtagta
     6541 tacacattat gttaactaac gctataaata acgattatgt tcccaaaaca atattttatg
     6601 aactataaca aaaatttgtt atcgcatatt gtatatttta attataggtg tataccactt
     6661 aaatttaaca caaaggcgtg attattttga aacccaaaaa gaaaatttat ctaggtctcc
     6721 tcttttcctt gatgattgga atttttagta taggaattac aaatacctat gcttcagaaa
     6781 attctaattt caatatcaac tcccaaccaa ttgaagaaca agcaattaat tttgcgaaaa
     6841 ctgattttga acactccata acttcaattc ttttaatgga aaataacacc gaaactgata
     6901 ttaactatac tcttggttcg ccatttaaaa tgctcgatgg agaaaatacg gcaaatagtt
     6961 ctattttctt tccagtattt tcagacgctg ataatacgat taaatatatt tataccgtc
//
LOCUS       DAMEEU010000107         6934 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.111, whole genome shotgun sequence.
ACCESSION   DAMEEU010000107 DAMEEU010000000
VERSION     DAMEEU010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.111"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..614
                     /locus_tag="PB779_002614"
     CDS             <1..614
                     /locus_tag="PB779_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDE0740104.1"
                     /translation="VFAPLEGEDLASFLVGAAIMMIGMTLFLFGADYSMMEVGDLVGK
                     YMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQQVYDISDGEIGRVLLIGIVSVGTG
                     VFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFTSSEFMPIAFDSGGVTTGPVTVPFI
                     LALAGGMTSMIKQKKNENDSFGMVGIASLGPILAVMILGVIFQ"
     gene            611..1384
                     /locus_tag="PB779_002615"
     CDS             611..1384
                     /locus_tag="PB779_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HDE0740105.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            1381..1779
                     /locus_tag="PB779_002616"
     CDS             1381..1779
                     /locus_tag="PB779_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HDE0740106.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            1964..2635
                     /locus_tag="PB779_002617"
     CDS             1964..2635
                     /locus_tag="PB779_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740107.1"
                     /translation="MNFLVVLKDTLIERFTFLYVQLQENKTLLHFSPEFHLEGLTLGE
                     IYQAEGLSAVLHFFKVELELPVKDYIELSLESWDRAVVELFPEGLMIDTNDGKIHLTA
                     AELQKQMRYQIDDENSFSIFRRQQKILKSFLKVISKKRNLIKTTQLLKKYPGLLHTSI
                     QFPQLITMIHRFIRMQQLPSKKLFLPLTDTFRVVNREDKKKVIVIDFTRNRNVLHQVA
                     MEKAN"
     gene            2694..3134
                     /locus_tag="PB779_002618"
     CDS             2694..3134
                     /locus_tag="PB779_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740108.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            3146..3814
                     /locus_tag="PB779_002619"
     CDS             3146..3814
                     /locus_tag="PB779_002619"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HDE0740109.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            3878..4501
                     /locus_tag="PB779_002620"
     CDS             3878..4501
                     /locus_tag="PB779_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HDE0740110.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            4557..4943
                     /locus_tag="PB779_002621"
     CDS             4557..4943
                     /locus_tag="PB779_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HDE0740111.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            5156..6547
                     /locus_tag="PB779_002622"
     CDS             5156..6547
                     /locus_tag="PB779_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HDE0740112.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
BASE COUNT         2204 a         1129 c         1542 g         2059 t
ORIGIN      
        1 ttgtttttgc accgttagaa ggagaagacc tcgcttcatt tctggttggt gcggcaatca
       61 tgatgatcgg aatgacgctc tttttgtttg gagcagatta ttctatgatg gaagtcggag
      121 atctagtagg gaaatatatg atcaaaaaga aaagtttgac cgttttggtc agtttgggat
      181 ttgctatcgg gatcgtgatc acgattgctg aaccttccgt gcaagttttg ggacaacaag
      241 tatatgatat atctgacgga gagattggca gagtgttgct gattgggatc gtcagcgtcg
      301 gcactggagt atttctagcc tttgcgctgc ttcgggtcgt attcaagcta tcctattatc
      361 aattgatggc tataggctac ataggcgttt tgatcgcctc atttttcacc agttccgaat
      421 ttatgccgat tgcttttgat tcggggggag tgactactgg tccagtaact gttccattta
      481 tcttggccct tgccggaggg atgactagta tgatcaaaca aaagaaaaat gaaaatgaca
      541 gttttggaat ggtcggtatt gcttcgttag ggccgattct tgccgtgatg attttggggg
      601 tgatcttcca atgagtttct ggcagcaagt gatagatgga atcgaaatcg ttaccatgga
      661 agtcattttg gcagtggcac ctatcgtaat cctatttgtt ttaatgaata tcattagttt
      721 tcgtatgcgc aaaaagcgtt tctttgacat tatgaaaggt ttcttgataa cgactattgg
      781 gttgatcctt ttcctgcacg gagtcaatat ggcttatgta ccggtaggac agcatttagg
      841 cagtgctatt gcgggattgc cttacaatta tatactggtt ccccttggct ttttaatggg
      901 gttcttagta gggtttgctg agccggcgat tcatgtaatg atcaaacagg ttgaagaatt
      961 gagcgagggg agaatccgat cgaaaatcat gctgatggta atttcaattg ggatcggcgc
     1021 agcagtagga ttgtctatgt ggcgtttgct cgtcggattc tctctttatt atttcttgat
     1081 cccaggatac gggctagcat ttattttagg acgaaaagtg gacaagatct ttttagcaat
     1141 ggcttttgat aacggtggag tagcaacggg cccgatgtgt tcgacattta ttttatcaat
     1201 gagcgtggca atcgctgcac aaattgaagg aagagatccg atcattgacg ggtttggtgt
     1261 ggttgcaatg attgcattga caccaatatt atccacttta gtactaggat atatttataa
     1321 acgaaaagat gaaaaagaca gaatcgaaaa agaaagattg caaaaattgg gggaaagcaa
     1381 atgaaagatc ttgtagcatt gaatcttcac atgattgtga cgatcgttga cggaggaatg
     1441 ggcgaagatg ttatcgactt ttcaaaagaa gcaggtgcag caggcggaac gatcttacat
     1501 ggaagaggtt ctggtgtaca tgattcaggg aaatttttag gtttggacat ttcgccagaa
     1561 aaagatattg tgttgacatt agtacccgat agtttgacga ataaagtaat ggatgcgatt
     1621 ggtcaaggca tcaacatcga tattccaggt aatggtattt gttttagtat tgatgtagac
     1681 aaagtcattg gtatcactaa gattcatcaa tatcgagaaa ttatcggaat gcaagaactt
     1741 ttagatgaaa ataacgatag agaaaagtct gaatcataga caagcgtttg aagaggaaat
     1801 aaacacaaac aagaaggcgg atgagcgtta tttccgcttt tttgtttgta tttttctcgt
     1861 gaatacttat gaaatagtaa atttttatga aattctactc taagcatcag actttctttt
     1921 caaaatatgc tattttaaaa atgatgaaaa aagggggaga aaaatgaatt ttttagttgt
     1981 tttaaaagat actctgattg agcgatttac atttctatat gttcaattgc aggaaaataa
     2041 aacattgctg catttttcac cagagttcca tctagagggg ctaacattag gagaaatcta
     2101 tcaagcagaa gggctgtcgg ctgttttgca cttttttaag gtagaattgg aattaccagt
     2161 aaaagattat atcgagcttt ctcttgaatc ttgggatcga gcagtggttg aactgtttcc
     2221 agaaggttta atgatcgata caaacgatgg gaagatccat ctgactgcag cagaactgca
     2281 aaaacaaatg cgttatcaaa tagatgacga aaattctttt tctattttta gacgtcagca
     2341 aaagattcta aaaagctttt taaaagtgat cagtaaaaaa cggaatctga tcaaaacgac
     2401 acagctgttg aaaaaatatc caggtctgct tcacacgtct attcaatttc ctcaattgat
     2461 tacgatgatc catcgtttta tacgtatgca acagctacca tctaagaagc tgtttcttcc
     2521 attgacggac acatttcgag tagtcaacag agaagataaa aagaaagtga ttgtgattga
     2581 ctttaccaga aatcggaatg tccttcacca agttgcaatg gaaaaggcca attaaggctt
     2641 tttctttttg gatttttttg tcataataaa tattagatga tggaggagat aatatgatgc
     2701 aaacatggtt agaaaggcta atacgatttc agcagaacta tcacaaactt atgcagggaa
     2761 gatatgcgaa atttgatcag ttgaatcgcg gtctattgat cgctgcgctt gtctttagtt
     2821 tgctaagtcg ttggttgccc tatagaatcg gacaattgtt gttcatcgtc tttttcggat
     2881 ggatgatatt tcgtttccta tcaaaaaaaa tctaccccag actaaatgag aatcaacgtt
     2941 atttgaaata tcttgataga gtcaaagaaa aatatcatca gataaaaaac aaaaagcaag
     3001 tcaaaatgga tcgaaaaagt tatacttttt ttgagtgccc gaattgtcat caaaagcagc
     3061 gtgcacctaa aggaaaagga cgaatacgtg tgacatgcaa aacatgtggt ataaaattcg
     3121 aaacgaatgt ttaagggaga aaagaatgaa attagtatta ttacgtcatg gcgaaagcga
     3181 agcaaatttt gaaaattact ggacaggatg gctagatgtc gccttaacag aaaaaggaaa
     3241 agaacaagca gcagttgccg gtcaaaaaat gcttgaagcc ggacttcaat tcgatgccgt
     3301 ttatacctct gttttgaaac gtgcgattct taccggacaa gtcgcactag aagaaatggg
     3361 tcagttatgg cttcctataa taaaaacatg gcgtctaaat gaacggcatt atggggatct
     3421 tgtgggtaaa aacaaagata agatgaaaga aatatacgga aaagatcaag taaaaacatg
     3481 gcgcagagga tatacggaag ttccgccgtt aaccgcagaa aatagatttg accgcagata
     3541 tgatcacttg gatccgcatt tgatcccata cggagaaagt ctggaaatga cagtgaatcg
     3601 gatcattccc ttatggcaag atcatctagc accaaaacta aaagatcggc aagatttact
     3661 agttgtgggt catggtaata gcatccgagc actgacaaaa tatttagaag atgttcctga
     3721 agatcaaatg gatacgatcg atatcccaaa tgcacaacca atccagtata cattagcaga
     3781 tgatttgaca attctggaca aaaaaatact ttaaagaaca cctttatcta aaagtgagag
     3841 atagaaaaaa gaagcaaagg aatggaacaa aaggaacatg aaaaattata tatgggactt
     3901 tgatggtaca ttgtttgata cgtatcccgc aatggtagat ggtgcatggc aagcactaaa
     3961 agattttggt atcagtatgg acaaaaaaga aatctacttc aaaatgaaaa agtattctac
     4021 tagttatttg atcaatgaat caaacttgaa tgccagagag tttaatgaat tatttcaccg
     4081 atatgaaaaa gaaagtacgg aagtttcccg tccatttcca gaaacgaaac aagtactgga
     4141 aatgctaaaa gacaacggcg gtcgtcattt catcctgacc caccgtttga cagaatcaac
     4201 atggggcctg ttaaaagaac atcgattggc acatctgatt gaggaagtag tagggatcga
     4261 tcaggacttt cctcgtaaac ctgatccagc atctttaaat tatttgatcg atacttttca
     4321 tttagaaaga acagacacga tgatgatcgg cgatcgtcgt ttagatatcg aagcagggaa
     4381 aaatgcagga gtcgctactt gtctttacga catcgatcat tttctgggtg agatcccggc
     4441 agattatgtg gtaggaaatc tgaatgaaat ccttaccttg cagagcatca ttaaaaagta
     4501 gtatcccctt tcaaaggaga tatgttataa ttttcataaa ggagtgataa aattatatgg
     4561 aaatcagaag acaaaaagaa gttgtagaag catttcatta tgatatgaga ttgccgaacc
     4621 aagaagtaga aacagatttg aaagtaggct tctcgccttt aaaagaaacg atcgaaaact
     4681 atccgaaaga acatagcatc gtaggagcac gcttagagtt ccgtttagtg tttgatacat
     4741 atgttttatc tggaagtgtg agtcagatca atcatatcct caatcggaaa attgaaggtc
     4801 aaaatgatgt cacacaagaa gaagtggacg agctagtagc accgttattc gatatcgtac
     4861 gccgaatgtc ttatgaggtg acagagatcg ccttagatca gcctggggta aaattgaatt
     4921 ttcaatcaga aaaacaagaa tagacagtaa aaacatacct gcgatagatt aaagctatca
     4981 caggtatgtt tttttattac taattgtaag caaaaagaat gtcatttcga taaaaatcgt
     5041 ctaaaatata aaagtcactg aaaaaaattt tttcaggagg atggttgaag aatcattctc
     5101 gggaaccttt acttccttcg atggacttgt cattaataat atgaggagga gaaaaatgac
     5161 aacactcatc acagttttag tggttctagt ttttgcggca ttattatatg tgttctatcg
     5221 tatgcaaaag cgccatacaa aattttcaac acgcgtcttt acagcattag gagttggtat
     5281 cgtctttggc ggtctgcttc aattgatctt tggtgtagac gacaaagtcg ttactcaatc
     5341 aatggaatgg atcgggattg taggtcaagg atatgtatca ttcttgcaaa tgctagttat
     5401 gcctttagtg tttatttcga tcattggtgc attcacaaaa atgaaagttt ctgaaaagct
     5461 agggaaaatt agtgcgactg tattgacttc tttacttgga acaacagcta ttgcagcatt
     5521 gatcggaatt ggttcaacaa tgctgttcgg actccaagga gctaaattca cacaaggagc
     5581 tgcagaaaca gcacgaatct ctgaactggc aacacgtcag gaaacagttg aaaacttatc
     5641 gattccacag cagattttat cctttatccc taaaaacgtt tttgctgatt tagcaggtag
     5701 tcgtgcaaca agtacgattg gagtcgttat tttcgcggca tttgtcggaa tcgcttatct
     5761 aggcgtgaaa agaaaagcgc caaaagaagc agcattcttt tcagatttag tcgacagtct
     5821 gtataaaatc attatgcgga tcgtgacgct tgttttgcgt ttgacacctt atggagtatt
     5881 tgctttgatg acaaacgttt tggcaacaag tgattttgca gctatcgtca atttaggtaa
     5941 atttgtcgtt gcttcttacg tagcattgct tgctgttttg attgtccact cactgatttt
     6001 gattggtgca aaagtcaatc caatcaacta tttcaaaaaa gcctttccgg tattgagctt
     6061 tgcgtttact tcacgttcaa gtgctggagc tttgccattg aatatcgaga ctcagacaaa
     6121 agctttagga gtagatgatg caacagctaa tttctcagca agttttggtt tgtctattgg
     6181 acaaaacggc tgtgctggcg tttatccagc tatgttggca acgatcgtcg caccagcagc
     6241 tggagtgaat gtctttagtt tggaatttat tttgatgctt gtggcaattg taacaatcag
     6301 ttcttttggt gtagctggag tcggtggggg cgcaacattt gcttcactga tcgttttagg
     6361 ggcaatgaac ttgccagtag caatcgttgg gttagttatc tctgttgaac cattaatcga
     6421 tatggcacgt acagcagtaa acgtcagcgg tagcatggta gctggtatcg tgacaagtgc
     6481 acgcatcaaa gatttagatc gcgatgtcat caatgatgat tctaaagtga tcgatgtgaa
     6541 tgcatagtca aaaagaggtt gtgatagaag tggtcagctt taagaaataa gaagaagttt
     6601 cctaaaaata gtttctcaaa tttttgtgaa atttcggctt atttccgaga agctacttct
     6661 gaaacaccgt gaataagagg ttgtgaaaaa gctgccctgc atcaagtaat aagaacagcc
     6721 aaacaaaaat agttcctcat attttacgtt tggttgagct tattaccgca gatgcaagct
     6781 tttgaacacc gtttaagaaa gaggtcgtga gcctgccgtt tcactctgag tcacaaagag
     6841 caatttcaaa aaatagcttc tcatgtttgt tgaatattgt gtcttgtgac cgaggagttg
     6901 tcaggagaac accgtttacc agaggttgtg actt
//
LOCUS       DAMEEU010000108         6720 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.112, whole genome shotgun sequence.
ACCESSION   DAMEEU010000108 DAMEEU010000000
VERSION     DAMEEU010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.112"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(407..1618)
                     /locus_tag="PB779_002623"
     CDS             complement(407..1618)
                     /locus_tag="PB779_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HDE0740113.1"
                     /translation="MSEVTGYLEQVDNETYRLRAVLGYKPDGSAKRKSKTIKANSKRA
                     AYKELNIWLEQFEGMTDDSLDLFNITFGEFYRKIWLSEAEKNLEPKSYHNYKRMIENR
                     FLDKFDFIPLIDIKPYMIKKIVVNAQRINTKDPGRNSDKPLSRNTKLRMLYAVNNLFL
                     MAKNEYGAIKENPVENVKIPKEKGVKKNIEEPYSEEEIHAMLKAAFEESIEIKTLIVL
                     AFITGARQGEIAALEEKDIDFDKQEIRFHQRISEVDGKSDIRLLPGLKNDDDEKIVTG
                     PAYLFDMLDELIKENKKIRWKLNIKKLRHYFIFDTKQDGTLPRGSYLYKKFKRFTKRH
                     NLRHIRFHDIRHTSATYLLSDPNMTPKELQKRLGHRDFNTTMNVYGHVLRKEKDTATT
                     AFEKLLKKDIK"
     gene            complement(1736..2371)
                     /locus_tag="PB779_002624"
     CDS             complement(1736..2371)
                     /locus_tag="PB779_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4352 domain-containing protein"
                     /protein_id="HDE0740114.1"
                     /translation="MAKKVMGQDGKMYKVKKPFYKRVWFWVLIVLLFFGIGGALSGGE
                     NKDSATATSTSTNKETTKETTTKEEKTYKIGDDVAVGKMEYKVNSVEVVKQVGPSVLP
                     TNAKDTFLVVDLSVKNAGDKAVTVDSSFFKLKADGKTFEADSAASMSANQDENGNITN
                     SFFMESLNPDMQQTGKIVFDISEAQANAQNNVLQAQTGYFGTETVSIALHN"
     gene            complement(2454..2876)
                     /locus_tag="PB779_002625"
     CDS             complement(2454..2876)
                     /locus_tag="PB779_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HDE0740115.1"
                     /translation="MYLKLKEMLSEYNLKLIYMEMEEPGFYYPKPRIVFLNEKLHEDS
                     SEAFHLAHELGHFIASHFEYSVLYDNSTTFHSKFEAEADRIAIMILLNIFIENELTDE
                     SQFKLENFMEFYSINNKLRTECFNVCQSYFKKKYSYAQ"
     gene            complement(2894..3214)
                     /locus_tag="PB779_002626"
     CDS             complement(2894..3214)
                     /locus_tag="PB779_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740116.1"
                     /translation="MTLFERIKSLASQRDKSMKEVALELGFSENLFYRWKTTEPKARD
                     LQKVADYFNVSVDYLLGREEKETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            3507..3698
                     /locus_tag="PB779_002627"
     CDS             3507..3698
                     /locus_tag="PB779_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740117.1"
                     /translation="MSNLDNGRAAIKKFMRENGVTMEDLATAYGYTRVRMQQIIDGHW
                     SGPKANKTILEIIRDYRIR"
     gene            3712..3963
                     /locus_tag="PB779_002628"
     CDS             3712..3963
                     /locus_tag="PB779_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740118.1"
                     /translation="MEQLALVNLSALKASLAESEIANEVWDTKQAAEYLKTTTRTLTK
                     DAESGKIPAAKVGREWRFSSIALYQYLKGGKTWANSTEH"
     gene            3939..4118
                     /locus_tag="PB779_002629"
     CDS             3939..4118
                     /locus_tag="PB779_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740119.1"
                     /translation="MGKFNRALVFSTPFIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(4161..4631)
                     /locus_tag="PB779_002630"
     CDS             complement(4161..4631)
                     /locus_tag="PB779_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740120.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            4718..5416
                     /locus_tag="PB779_002631"
     CDS             4718..5416
                     /locus_tag="PB779_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HDE0740121.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            5594..5935
                     /locus_tag="PB779_002632"
     CDS             5594..5935
                     /locus_tag="PB779_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740122.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            5928..6599
                     /locus_tag="PB779_002633"
     CDS             5928..6599
                     /locus_tag="PB779_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HDE0740123.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
BASE COUNT         2180 a         1101 c         1194 g         2245 t
ORIGIN      
        1 tgaaaatatg cttctatcat tacaagctcg tttggtgtaa gatgggtata agtcatttat
       61 gttcactctc cttgtatgct ttagcgggta ttacaatttg agtgtaacat aaatggcttt
      121 tttatttgtc tcgcttaatt atacaaacgg cgaaaataaa aaaagaacag cgtaaatgtt
      181 ttcgaaatgc tttcgcacca acatttacct gttccgtggg tttggcaccc aatgggccgt
      241 gaggggctcg aacccgcgac ccgctgatta agagttcgtt atttaatggt attttaaatg
      301 aagataagcg aatttacagc atttttaaat gcttatatac cgcaaattat cccaagtttt
      361 tatatatcct acccgagttt atacccgaaa atataatttt ttagtgttat tttatatctt
      421 tttttaatag tttttcaaac gctgtagttg ctgtatcttt ttctttgcgt aagacatggc
      481 cataaacatt cattgtagta ttaaaatctc ggtgtcctaa tcgtttttga agctcttttg
      541 gagtcatatt aggatcgcta agcaaatagg tagctgatgt atgtctaatg tcgtgaaaac
      601 gaatgtgacg caaattgtga cgtttggtga atcgtttgaa cttcttatac agataacttc
      661 cacgtggtaa agttccgtct tgttttgtat caaatataaa atagtgtctt aatttcttta
      721 tatttaattt ccaacgaatt tttttattct ctttgatcaa ttcatctaac atatcaaata
      781 gataagcagg accggttact attttttcat catcatcatt tttcaaacct ggcagcaacc
      841 gaatatctga ttttccatcc acttctgaaa tccgctgatg aaatcttatt tcttgtttgt
      901 caaagtcaat atctttttct tctaaagctg caatttctcc ttgtcttgct cctgtaataa
      961 atgctagaac aattaaagtt ttaatttcta tgctttcctc aaatgctgct tttagcattg
     1021 catgaatttc ttcttccgaa taaggttctt cgatattctt ttttacgcct ttttcttttg
     1081 gtatttttac attttccaca ggattttctt taattgctcc gtactcattt ttagccatca
     1141 aaaataagtt gttaacggcg tataacatac gaagctttgt atttcttgat aaaggtttat
     1201 cagagtttct tccaggatct tttgtattga ttctttgagc attaacaaca attttcttta
     1261 tcatgtatgg ttttatatcg attagaggga taaaatcaaa tttatcaaga aatctattct
     1321 cgatcattcg cttatagtta tgataagact ttggctctaa atttttttcg gcctctgaaa
     1381 gccatatttt tctataaaat tcaccaaaag ttatattgaa taaatccaac gaatcatcgg
     1441 tcattccttc gaattgctct aaccagatgt tcaattcttt atatgccgct cttttactat
     1501 tcgcttttat agttttgctt tttctttttg ccgagccatc aggtttgtac cctaatacag
     1561 ctcttagtct atatgtttca ttgtctactt gttctaagta tcctgttact tctgacataa
     1621 ttgaatcagc tctctttctc tgatacaata ggtactataa agaagcctat tgtgtaggtt
     1681 tgttttttct tagaacacgc tcgctttggt cggtggggcg tgttttttat actaattagt
     1741 tatgaagagc aattgaaact gtctctgttc caaagtaacc tgtttgtgct tgcaatacat
     1801 tattttgtgc atttgcttgg gcttcagaga tatcaaaaac tattttacca gtttgttgca
     1861 tatcaggatt taagctttcc ataaagaaag agttagtgat attaccattt tcatcttgat
     1921 ttgccgacat agatgcagcc gaatcagctt cgaaagtttt tccatctgct tttaatttga
     1981 agaatgagct atcaacagtc acagccttat cacctgcatt ttttacagat aagtcaacta
     2041 ctaagaaagt gtcttttgcg ttagtaggaa gtacagatgg gccaacttgt tttactactt
     2101 caacggagtt tactttgtat tccattttcc ctacagcaac gtcatcaccg attttataag
     2161 tcttttcttc ttttgttgta gtttcttttg tagtttcttt attagtactt gttgatgttg
     2221 cagtagctga atctttgttt tcaccgccac ttagagcacc accaatacca aaaaacaaaa
     2281 gtactattaa tacccaaaac catacccgtt tataaaacgg ttttttaacc ttatacattt
     2341 tcccatcttg acccataact ttttttgcca tttaaatatc cctcacttct tgttataata
     2401 tatttgtgat ctcagaaatg aggtatgagt ccgtgttgca gcacgggctt tttttactgt
     2461 gcataagagt attttttctt gaaatatgac tggcaaacat taaaacattc tgttcttaac
     2521 ttattattga tagagtagaa ttccatgaaa ttttctaatt tgaactgaga ttcatcagtc
     2581 aattcgttct caataaagat atttagtaaa atcataattg cgattctatc agcttcagct
     2641 tcgaattttg aatgaaaagt tgtagagtta tcgtacagta ctgaatattc aaaatgtgaa
     2701 gcaatgaaat gaccgagctc atgggctaaa tgaaaagctt cagaactgtc ttcgtgtagt
     2761 ttttcattca aaaatactat tcttggtttt ggataataaa aacctggttc ttccatttcc
     2821 atatagatta actttaaatt atactcactc agcatttctt tcaactttaa atacatacaa
     2881 cccatcactc caactattca ttttcctcta aagctttagc aattgcaatc gctttacgca
     2941 ttgtctcctt agatatttct tttccatcaa aagaaaatac agtatcatct tctgataaat
     3001 ccacatgttt aggcgtttct ttttcttctc tacctagaag atagtctaca gagacattga
     3061 aatagtcagc taccttttgc aaatctcttg ctttgggttc tgttgttttc catcgataga
     3121 aaagattttc gctaaatcct aattctaaag cgacttcttt catgctttta tctctttggc
     3181 tagctaatga ttttatcctt tcaaacagtg tcataataat gttctccaat cctaaacaaa
     3241 taaaagtaca caaaatgtaa attatactgt tgacataagt ataagtttgt attattattt
     3301 gtttgtaagt taatttgata gaaaaaaagc aaactaaaaa tacaccttat agcattaagt
     3361 ttggcgaccg attgcataat aaagggtttg ttgtaggctt atttaactat gtttatatag
     3421 tatacgattg tatactatta gtcaatagtt tatacgtttt ttctatcatt ttgacttaca
     3481 aatctatatg taaggggagt gaatagatgt caaatctaga taacggccgt gctgcaatca
     3541 agaagtttat gcgagaaaac ggagtaacta tggaagattt ggctactgca tatggataca
     3601 cacgtgttcg aatgcagcaa attattgatg gccattggag tggaccaaaa gctaataaaa
     3661 ctatcttaga aatcatccgt gattacagaa ttcgatagga ggaattaatc aatggaacaa
     3721 ctagctttag ttaacctctc agccctcaaa gcttctttgg cagaatctga gattgcaaat
     3781 gaagtgtggg atacaaagca agctgcggaa tatttgaaaa ccacgacacg cacgctaact
     3841 aaagatgccg aatctggaaa gattccagca gcgaaagttg gcagagagtg gaggtttagt
     3901 agtatcgctt tgtatcagta tctaaaagga ggaaaaacat gggcaaattc aacagagcac
     3961 tagtattcag cacaccattc atcatctacg ctttaggcct ctggggaagc aggcaagcgt
     4021 tgataggaac gattgtttac atggtttgga tttttatggg gcttgatgaa gctgaagctg
     4081 agtacagagc gaaaaagcca accgaggggg ctgactaaaa atgaatagaa aagagaaact
     4141 agaatgtata ttactattac tcagtttaat tctttcacta atttctctat tgggaagttt
     4201 gtatttttga tatcaacaat tttgtggatt tgggttctat ttagagtaaa tatcattttt
     4261 gtttggtgat taaggagttt attaaaatta attttcccta cttcaaatgc aaggtaacaa
     4321 gatatagcac ttttaggagg aatatttagc ggtacagctt cagagtatat tctattatca
     4381 tcgactgatc ctcctttagc aattaatttc ttaaatggag tagctgacca tctgcggttt
     4441 aagttagcgg atgaaagttc taaattaact aacatagctg gttctgttga atagttagaa
     4501 atgattactt ttgtataaat catatctgca gcgaagtaag aagcattaag ttcaacttct
     4561 agttgagggc gcattccttt tatttttatc cctgttaaaa acgtactcaa tataaaactt
     4621 attattgaca tccattgaaa aattgttaag tgaaaaaaat tcaaaataaa caccaccagt
     4681 ttttaactaa attataccaa aaaggagaga agaaataatg caagaattag taattttgaa
     4741 aaataaagaa gctgtgacta cgagcttaca agtggcagaa agcttcgaga aaaaacatca
     4801 acatgtttta agagatattg atgcactaaa aaaagatgtg tccaattttg gacagatgtt
     4861 tgtagaaggt aatgaaccag attcatatgg cagaaatcga cgagttttct tcattagtag
     4921 agatggattt ttcttgctgg ctatggggtt tacaggaaag aaagctatct acttcaaaca
     4981 aaaatacatt gaagcattca acgaaatgga agatgttatt cgcaagaata ctgttcctca
     5041 aacaattgaa gatatgatga tctatcaatt agaagaaatg aaagatgtta aaaaagatgt
     5101 ttccatgctt aaagatacta tgcgaattag cggacaacaa gagtttgaaa ttaagcaaaa
     5161 aggaaatatg aaagttatgg gagttctagg gggaaaagaa agccgagctt atgaagaaat
     5221 cagcaaaaaa gtattctcaa aattttggtc tgaatttaaa cgtacctttt caatcccaag
     5281 atatggcgag ttacctcgta agagattcga tgatgctgtt tcatttattg aaatgtggtt
     5341 gccagaaact gcgatccgta tggaaattga tcaactgaac agacaacaga gactttttgg
     5401 tgatgacaat gaatagagct gaagcgctaa gaatagggac ggcaattgct aattgctggt
     5461 ggaaatacta taaaccaatc atcctaagcc aacaacatat tgacaagcaa aaagcatggc
     5521 aacaaataaa aaagtgactc cgccggcaag caaagagtca caaagaaaac acatcataag
     5581 gagattttag catatggaaa aagaactttc cactctagat caatatttga ttgatcctga
     5641 ttggggcaag ccgaaaattg aggaaacaag tggtcgaaaa atcagacgaa atcttttgac
     5701 gaatgaagaa ctagcttggg atcaagatga tttaggcaac catgtaacta tttgggatca
     5761 tgtttatctt atccatctat cgaagcattc gaataaacct gaatatattt acgtcatcga
     5821 agatggcttg attgatgcgc tagaagagta cgacagagat aacttgattg atatctctta
     5881 ttacggacca ggtaagaaat acattgctga aatggaggca gaatttgatg agtgaaatca
     5941 aagggacaac gaactttgaa aaacttttta gtcgtaagtt aaataaaatt ctcaagaaaa
     6001 aaggaaattt tgattattta tcttgggctc acgcgtggga gattatgaaa aagaatgatc
     6061 cacaggcaac ggtaactatt aatgagtaca aacactacag ggttgtttct ggaactcatc
     6121 aagactttct tgttgaggaa tataaacctt ttcttatgga tgaaactggg acttatgtat
     6181 ctgtctcagt aacggttaaa ggacacacgg aaaccgaatt atttcctgtt ttagattatc
     6241 gaaaccaacc agttgttaaa ccaaatgcaa tgcaaatcaa taactcattg aagcgatgct
     6301 ttgtgaaagc attggctcta cacggactgg gattatatgt atttcaaggg gaagatattc
     6361 caacaccacc tagaatcgat acaaagaaat taaacatgct agagacgatt ctagaagctt
     6421 tcaatgagca gatgggtaaa gatatgacca aaaccttaat cgaatatgtt aatgagcaga
     6481 cagataaatt agggctctta gctgataacg ttgaaactat tgaacagtta agctatgagc
     6541 aatgtgcctt gatggagcga gcaatagcag ctaagagaaa agaattagat aagaagtgat
     6601 atgagtgttt aaaccattaa tcgattcata ttcagcggtt ctgaaaaagt tcaaaggaaa
     6661 agacataagc gcaaccatca atgaggaagt gaacattgat cgactaaaga cgatgtatga
//
LOCUS       DAMEEU010000109         6719 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.113, whole genome shotgun sequence.
ACCESSION   DAMEEU010000109 DAMEEU010000000
VERSION     DAMEEU010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6719)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6719)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6719
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.113"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..546
                     /locus_tag="PB779_002634"
     CDS             <1..546
                     /locus_tag="PB779_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDE0740124.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IKQKLNWQSPVQFRKTTVTVV"
     gene            complement(716..1678)
                     /locus_tag="PB779_002635"
     CDS             complement(716..1678)
                     /locus_tag="PB779_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0740125.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1680..3119)
                     /locus_tag="PB779_002636"
     CDS             complement(1680..3119)
                     /locus_tag="PB779_002636"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HDE0740126.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            3304..5250
                     /locus_tag="PB779_002637"
     CDS             3304..5250
                     /locus_tag="PB779_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HDE0740127.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKIDGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5514..6386
                     /locus_tag="PB779_002638"
     CDS             5514..6386
                     /locus_tag="PB779_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HDE0740128.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         2156 a         1149 c         1204 g         2210 t
ORIGIN      
        1 atccatcgtc gtttctacac cagtatctgc catcagaaaa tcacgacgga tacaactgaa
       61 tttaaatacc atgaagtgga tgccaaaggc attatccgtc aaaagaaatt gtatctagat
      121 ccttttatgg atatgttcaa tagtgagatt ttatcctatc gtatctctga aaagcccaat
      181 gcattagcgg taatggaagg tttggaggaa gctatccaga ccactaacga ttgtccctat
      241 cgtcgtacgt ttcactcaga tcaaggttgg gcgtatcaaa tgaaagctta tagaaacaaa
      301 ttgaaggagt acaaaatctt tcaaagcatg tctcggaaag ggaactgctt agataattca
      361 cttatggaga atttttttgg cttattaaaa caagagattt ttcacgggaa agtttataac
      421 tgtttcgagg aattaaaatc agccatcgat agctatatct attactacaa taatgaacgg
      481 ataaaacaga aattaaactg gcaaagtccc gtccaatttc gtaaaacaac cgtaacagtt
      541 gtgtaaaaat atcattttag agcatgaaaa aaggagtgga tttctccact ccaaaaaagt
      601 ctaacttttg ggggtcacta caagttgaca actccttttt gtttacaaat caattggata
      661 tctacaaatt gtattttcta acgaatttta tagacattaa aaaattaatt taacgttaaa
      721 tacttcctcc agaaagtatt gagattggta aaatataatc cttatttgtc ttttcgcctt
      781 taattttttt cagaagaata tcaacaataa gacttgcaat ttcatcaatt ggttgtctta
      841 ttgttgtcaa ttgtgggaaa aatttctcaa tgaaagaggt accatcgtat ccaataattt
      901 ttaaatcttc tgggatatta agtttaagtt gatgagcaat tttcatagtg agaatggctg
      961 ttaaatcatc agaaacaaaa ataccatctg gtttgtgatt tataatagtt gactttattt
     1021 ccatttcacg acggatagta gacagattat taggaatttt gaaaattttt ccatttggat
     1081 tttgaaaaga aaaacctagt gcacgtaatt ctgtgggaga atccgtgtta tcatttcctg
     1141 taatcataat ggtattttga caaccatttt tttgtaaagt cttagctgca agttttcccc
     1201 cttcaaagtt atctgaagaa acaatggaaa cattaggagc taaatttcta tcaaaagcaa
     1261 caataggtgc tctcacacgc tcataatcag caattccaag attatggctt gatgagatta
     1321 tgccatcaac ttggttggct tcaagcattt caatgtattc tctctcttta gcaggatcat
     1381 tttgactatt gcaaataatc gttttatatc catgtttaaa taactctatt tcgagatact
     1441 caatgagttc agagtaaaag atattactaa tattaggaaa aataagacca ataagctgag
     1501 gtgactttcc ttgaagtcca cgtgctaaat tatttggttt ataaccaaga gttttcatag
     1561 cttcatgaac tttttgtttt gttttttctg ataaatatcc cttattatta atgacgcgtg
     1621 aaacggttgt tgggctaact ccagctaatt cagcgacatc agttaatttt gctaccattt
     1681 taatatttta attcaaagta ttttccagta ggttcgcctg atttgatttg aataccattt
     1741 tggtgatttt cagggaatac acgactagta aacacttttt ctcctttatt aataaaaatc
     1801 tcaatgattg agttatctac aaaaatgtta gcagttgttt ctttagtatc aattgagcat
     1861 tcacgaatcg taccaaagtc agtggcatat tgaatgcctg ctttgctgcg atctaaaata
     1921 atttttcctt ctttggtatc tacaatcaag ctaagtccat ttcctttact atcagagaaa
     1981 agaagtaact ccgatttctg atttggagga aaagttagtt caagctcata agtattattt
     2041 gtttctgctt ttgctgtaaa ttgttcagaa ctagcacgta atgatgtaat agcttctact
     2101 ggatattggt aaagtttacc atcttttatt gaaagttctt ttacaagact cattgctccc
     2161 tgataatcat acttatcagt tggataatcg atatcaggta gtccaatcca actgacaatc
     2221 agagcacgac catcaggagt attgaatcct tgagtcgcat acgcttcaaa tccataatca
     2281 agattttgaa tttctgaagc gcccacaagt tttacttttt ctatgtcaag cgattgacag
     2341 atcttaaaag tattcggata gatattccca taatttagct cagatttatc caacccttga
     2401 ggacaataaa tgagaacagg ttttttgtct acaaatacta gatttggaca ctcaatcatg
     2461 tattctgaac cagtgccgcc aaaatcaagg ttgccaactt cctcccatgt ttccacgtta
     2521 ttgtcatccg ctttgtaaag tttgataaag cctgattttt ctaaattttg tgctccaaca
     2581 atcgcataca attgtccttc ataattaaac atttgtggat cacgaaaatg atcagttaca
     2641 tcagcaggtt tatgaataag aacattctca cctttcgtaa tgttgtagtc tttatccatc
     2701 catgctccga tttgaagtgt atcacgttcc caattttcat ttcgaacgtt tcctgtatag
     2761 agtaagaata gattcccctc tatttcatat gcagaaccgg aataagcgcc gtggctatct
     2821 cgttttgtgt ctggaagaag ttctgctcct gttacatgaa aatgaactaa atcatctgat
     2881 tcattgtgta cccattcttt caacccatga gcagctccaa atggccaatt ttgataaaaa
     2941 agcgtatatt ttccgttaaa aaaagaaaaa ccattaggat cgtttaacaa tcctgtttta
     3001 ggttcgatat gatagctagc acgccaaggt gatcgtttta cattatcctt aattttatcc
     3061 atctcatctt tagtccaatc agaataagca cgatatcgta tttctcgagg taagttcata
     3121 ttttactcct tcaatttatc tttttacaac tagtatggta aacgttttcc gttgaaaaat
     3181 caatcatttc atttaaaaaa ataaactata tgacaaacgt ttgacatatt tttaagatat
     3241 gctaaaataa atttgcattt cagtgaaccg ttttcacgta aaaataaaaa aggagtgatt
     3301 cgaatgaatt acagtaaagt agcttccgac gtaatacaag cggtcggaaa agataacctt
     3361 attgcagctg cacactgcgc tacacgtctt cgtctcgtac taaaagatga cacgaaagtg
     3421 aatcaaaaag ctttagacga aaatccagat gtgaaaagca catttaaaat tgatggacaa
     3481 tatcaagtga ttatcggtgc aggtgatgtt aatttcgttt atgacgaact tatcaaaaaa
     3541 actggacttt cggaaatttc aacagatgat ttaaaacaaa ttgctagtaa agataaaaaa
     3601 ttcaacccca ttatggcatt aattaaatta ttatcagata tttttgttcc aattatacct
     3661 gcccttgttg caggtggttt attaatggca ttacaaaact ttttaacagc tgctggactt
     3721 tttggaccaa aatcaattga agaaatgtat cctgcgattg aaggtatttc ctcaatgatc
     3781 caactgatgt ccgctgcacc attcatgttc ttaccaattt tagtaggtat ttcagctgct
     3841 aaacgttttg gagcaaacca atttcttggt gctgcaattg gtatgatcat gacaacacca
     3901 gatcttggtg gctcaactga atattggaat atttttggtt atcatgtttc acaaacaaac
     3961 tatgcttatc aagttattcc agttttagca gctgtttgga tattatctat attagaaaaa
     4021 ttctttcata aaaaattgcc atcatctatt gactttacat tcacgccatt attatcagta
     4081 atgattactg gatttttgac tttcacagtt attggccctg taatgttatt gttgtctaat
     4141 ggaattacag acattattgt ttggctatat aacactactg gatttattgg aatgggtatt
     4201 tttggaggaa catattcact tatagtcatg actggtttac atcaatcatt tccagctatt
     4261 gaaactcaat tactttcagc gtggacaaat ggtatcggac atggagactt tatctttgta
     4321 gttgcatcta tggcaaacgt tgctcaaggt gctgcaacat ttgccatttg gttcttaact
     4381 aaaaattcta agacaaaaag tcttgcttcc tctgcgggtg tctcagcact tcttggaatt
     4441 acagagcctg ccttgttcgg agttaactta aaataccgct ttccattctt ttgtgcttta
     4501 attggttcag gaattgctac agcagtagca ggattactta aagtagttgc tgtttcactt
     4561 ggttcagcag gtttcttggg atttctttca attaatgcaa catctattcc attttacgta
     4621 ttgtgtgaat tgattagctt tgtagttgct tttgcaatta cttacttcta cggtaaaaca
     4681 aaagctgctg gtatctttaa agcagaagaa attgctgaac aaacaccagt taattcttca
     4741 aaagtagcaa caacagatcc aatatctact gatgttgaat caacacaaac aaaagtttca
     4801 tcagaaacaa ttgttagtcc catttctggt aaagtgatta gtctttcttc agtaaatgat
     4861 ccagtctttt catcagaagc tatgggaaaa gggattgcca ttaaaccaaa tggaaacacg
     4921 gtccattctc cagtagatgg tactattcaa ctcacgtttg aaactggaca tgcttatggt
     4981 attaaatcaa ataatggtgc tgaagttcta attcatattg gtattgatac tgtatcaatg
     5041 ggaggaaaag gatttacaca aaaagttact actaatcaaa aagttagaaa aggcgatatt
     5101 cttggagcat ttgaccgttc aatgattgag aaagaaggtc ttgatgatac aacaatgatt
     5161 attgtgacca atacttcgga ttattcagaa gtaaatatag tagctgaaaa tacagtcact
     5221 gagggtactg atttacttga aatcaaataa atgtatttcc ctgagtaaag atggaatttt
     5281 ctttccaaaa tcaaataata tagattaatc aaatatttga gaataacatt ttatttaatc
     5341 ttttcatata tcaattgtat gaaaaattat tagaatttta aaaaatgata aaaattcaaa
     5401 aggaaaaaat agtagttatt tacttgtcat gttactaaat aaaaaaataa tttaaatatg
     5461 atatatagtc atttatttag tgatttcatt ctaaaataaa gggagaaatg tctatgctat
     5521 acggtgcaat tgaagcaggc ggcacaaaat ttgtgtgtgc cattggcgat gaagaaatga
     5581 cgatcaagga aagagtgagc tttccgacaa cgacacctga ggaaacaatg cctttagtca
     5641 ttgacttctt caaacaatac caagcagatt tagcaggaat tgggattggc tcatttgggc
     5701 ctatcgatat ccatcgcgat tccgccactt atgggtacat tacctcgacc ccgaaattgg
     5761 catggcaaaa ttttgatttc atcggtacca tgaaaaaaga atttccgatc ccgatttctt
     5821 ggacaacaga tgtcaatgcg gctgcctatg gtgagtatgt cttcggcagt ggcaaaggat
     5881 tgagcagtgt cgtttactat acgatcggta cgggtgttgg cggcggtgcc ttacaagaag
     5941 ggcgctttat cgaagggttt agtcatccag aaatggggca tatgctcgtc gtccctcatc
     6001 caaaagatga ctttgctggc agctgtccat ttcatggcaa ctgtttagaa gggatggccg
     6061 ctggacccgc catcgaaaac cgcttaggga aaaaaggaca agaggttgca gaagatgatc
     6121 cttattggga aatcgaagcc tcctatattg ctcaatgtgc ctacaataca accttgatgt
     6181 tttctccaga tgtgatcatt tttggcggtg gtgtgatgaa acaacgccat atgctgcaaa
     6241 acgtccacga cgcatttgca aaattggtca atgggtatgt cgaaacacct gagttaagca
     6301 aatatatcgt gaccccagca ttagaagaca acgctggaac gctcggttgt ttggcattgg
     6361 ctcgagaagc ggtcttacat tcataaacga aaaaaggctc ttcgacattt agtgttggta
     6421 gagaaagata caactgaaaa tttagtcata accagttagg cagagtgctt aactggtttt
     6481 tgttttactt ggaagatcaa gccttgaatg agataaattc ttgctcgaaa gttatggaaa
     6541 tttcgatagc cgtaggccac ttgtattgtg caatagtttt ttacaaaaaa aagggggtgc
     6601 ggatattttt ttggacggtt ctgttgcaaa gttttaaatc tactatcaga taaggtagaa
     6661 taatagaaaa agatagcagg aggaatgacg atgagtcatt ttaaaggaaa gcaatttca
//
LOCUS       DAMEEU010000110         6642 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.114, whole genome shotgun sequence.
ACCESSION   DAMEEU010000110 DAMEEU010000000
VERSION     DAMEEU010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6642)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6642)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6642
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.114"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(1..859)
                     /locus_tag="PB779_002639"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="PB779_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="PB779_002640"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="PB779_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HDE0740129.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="PB779_002641"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="PB779_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2603..3421)
                     /locus_tag="PB779_002642"
     CDS             complement(2603..3421)
                     /locus_tag="PB779_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HDE0740130.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="PB779_002643"
     CDS             3582..4271
                     /locus_tag="PB779_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HDE0740131.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="PB779_002644"
     CDS             4285..5787
                     /locus_tag="PB779_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HDE0740132.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="PB779_002645"
     CDS             5800..6276
                     /locus_tag="PB779_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0740133.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="PB779_002646"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="PB779_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1203 g         2235 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag at
//
LOCUS       DAMEEU010000111         6350 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.115, whole genome shotgun sequence.
ACCESSION   DAMEEU010000111 DAMEEU010000000
VERSION     DAMEEU010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.115"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            290..1135
                     /locus_tag="PB779_002647"
     CDS             290..1135
                     /locus_tag="PB779_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0740134.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1416..2636
                     /locus_tag="PB779_002648"
     CDS             1416..2636
                     /locus_tag="PB779_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HDE0740135.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2633..5353
                     /locus_tag="PB779_002649"
     CDS             2633..5353
                     /locus_tag="PB779_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0740136.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5337..6281
                     /locus_tag="PB779_002650"
     CDS             5337..6281
                     /locus_tag="PB779_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HDE0740137.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
BASE COUNT         2363 a          983 c         1224 g         1780 t
ORIGIN      
        1 tttaaatctt ttgctaagtt gaactaatag agtcttttat gaatatcgaa gttagttttt
       61 cacctaactt cgttttttat agttggttat tataaaatag taatatagct gatttggatt
      121 caattcatat ttatttataa atcaaaaata cagagaatag tatataaatg tcctttccta
      181 ttcttaaaat gatgtttgta cttacttaaa ttaggtataa ttagtatatg ttttgtgaga
      241 aatttagact tacaataagc agtgaattta taatcaacgt ataggagaca tggatgaaat
      301 gaaactaatt ggtatagatt tagacggtac tcttttgaat tctgaccaga gcattagtca
      361 aaaaaatgca agaacaatga aacatttacc ggaagactgt tttccattca tttgttctgg
      421 aagagaagta gaagacatta ataatattct caaaaaatct ggtttaagga taccagcagt
      481 agggttaaat ggttctgttg gatttgatgg agaaaaaaag atatttgagt cttccttcga
      541 taaaaatgat gtaaaaaaaa ttgattctgt cctatcgaaa tttccaacca aaatatatac
      601 aaatctcgga agttatgaat ctcagaatta taaaaataaa atgaaaaaaa tttttcacga
      661 ggtagggagt gaattttcta tcaaagagct aaactatgag cttgagtatg aaaaatctat
      721 ttgttcaatc ccttataata atattgagga aattatagaa aaggatgcta tcagcattta
      781 caaatttttt atttttattc ctaatcgtca attgaaagct aatatattta accatttgaa
      841 aaagatgcta aatgtgtctg ttactgaatc ggcacctgta aatattgaaa tcgtacctca
      901 aaatgtatct aaaggtgtgg tgtttgatcg tttggaatca atctacaatt taaagaaacc
      961 tttgagaatc gcgatcggag atagtttaaa tgacttatct atgtttgaaa gtgcagatat
     1021 tagttttgca atgggaaata gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt
     1081 ttcaaatgat aaagacggag tatctcaagc atttgaaaga attcttacca tataaactaa
     1141 ttaaggtagt atagaacata gaattctaaa tacggaaaaa tggagcataa attccagtac
     1201 aaatagtact tcttcagtgt caaacgaagc gaatataaca tagatattta ggattgtgac
     1261 aaaaatcatg tcacaatctt tttttcgaat aaacttattt tttgaagtcg gccatttatc
     1321 gtaatttctt tgcataatac gaacaaattt tcggttattg atgaaaaaaa acattgaaaa
     1381 tggtatgata aaagaaaaaa aggaggaaat ttttaatggt gaaatttatc catgcggcag
     1441 atttacatat ggatcggtca tttgaaggac tgacaactct tgataaaact gtacaggaaa
     1501 aactattgaa gacgaatctg accgttttat caaatatcat tgaacaggca ataataaata
     1561 acgttgattt tgttttactt gcaggagata attttcatca aaatcgtcct tcattaaaaa
     1621 tacagaaaca tttttcagaa cagatgaaac ggttagaaaa gaaccatata cctgtattta
     1681 taatattcgg aaatcatgat ttctatcaaa aagagcggta ttggttctcc tttcctaaaa
     1741 atgtccattt atttacatcc gaaacggtag agacaaaaaa aataacgata aaaagtggag
     1801 aaactgtctc tctcagtgga tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga
     1861 tggaatttcc ttctagagaa ctcacagatt accatattgg gttgtaccac ggggaacctg
     1921 gcgtctctca aaaaggaaac tatgctcctt tccaaccctc aaagatgcaa gaaaagggat
     1981 acgattattg ggctttaggg catatccatg tgccaacggt cttaaatgaa aagcaaacaa
     2041 ttgtttatcc aggtgcgcct caaggtcata ctaaaaagga acaagcttct acatctattc
     2101 tactagttga attaagtaaa ggaagttgcc aaatacatcc gattaaagta gcagaggtct
     2161 attggaagac aaaggaaata tcattgagga aagcaagaac gacaaaagag gtcattgttc
     2221 acattcgtca gcagctttca aaagtagagg atggatttag tttaattgag ataaaattaa
     2281 aagattatga ccatctcaat acagatgttt tggaacggat acaatcagga gagctattag
     2341 actatttgtt agaggaattc tcagatagga taaatgattt ctttatttgg cgtatttctc
     2401 tcatagagaa tactttttat acgaagaccc cacttgctgc ttctgctaaa ttgatggaac
     2461 agttatttca atactatcag acacctcaag atttccaaca aattttaaat gaagtatata
     2521 gtcatcaaga agcggctaga atattgagcg aactgccgga atatcaagaa gaaacacttg
     2581 aaaaagccaa gcagctgctt aatcaagatt ttttatttga ggaggatcag gaatgaagat
     2641 tttaaggatc gagattgctg cttttggaaa atggcgtcaa aaaagttttg acttttattc
     2701 aggcaatcag ctgatctatg ggggaaacga agcaggaaaa tcaacgattt atcaatttat
     2761 tcaagcaata ttatttggtt tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa
     2821 agacggctca gcctatggcg gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc
     2881 tgtcgagcgc tacaagcagc aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt
     2941 gggaagtgat gagttactag aaaaactgat cgcacctttg acgaaagagt tattccagca
     3001 ggtatttact ttccagcaag agcagttgat ggaactagat catttgagag aaaaagagct
     3061 acatgatgcg ctgatttctt taggcatcac gggcagttct caagtattcc aaaagcggca
     3121 agaatattat cagaaagcac aacaattatt caagaaaaaa ggccaaaaat tactaatcaa
     3181 tcaaaaatta aatgaatgga aagagctgca agaaaaaatt catcaaaaac aagaacagga
     3241 agcttatttt ggcaagttga tccaacaaga acaggaatac gagtcgcaac agcagcagtt
     3301 attggcacaa ttaaaagagg cgaacaaaca attttcatta gccagacagc aagaacttaa
     3361 tttttcttta tatgaagaat ggcaatctct caaaaaaaac agcactacag gtcttcctga
     3421 tgagcaactt cttttagatc tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg
     3481 tttggaagaa ttagaagcaa cactggaaaa gcatagcggg atggatcagc agtcagccag
     3541 atattatttt tatttagagc aggagcagga actaaaagat ctccagcaac ttcaatttac
     3601 agcggaacaa ttaaacgaag aatggcaaag attacaaatt gagactagag aaacaaattc
     3661 agaattgaag attttggaac aaaggtggca ttggcagaaa aatccgttac cggaagaatt
     3721 tttatatgaa gaagaatgga agcatcttct ggctgaagaa agaaggattg ctgatctaga
     3781 aagccagatt tctgtgcgtc tccaaatagc taaagaacag caagagatga ttgaagcaga
     3841 agtgaatgac ttggaagaga cctatccagc attattacaa aatcagtcag agatagcacc
     3901 agtctcttca tctaaaccgt atatgctgat ggctggcgga gcaataatca ttgcaggtat
     3961 atttgtacca atgcccttga aagtgatcct tttactaatt ggtgcaggca tgattggcta
     4021 tttcttctac aaaaggcaac caaaaattaa aactaaaaat gatttctctg agataaaagg
     4081 aatgtggcaa gaaaaactag gacaacttga tctagcctta gctcaattag ctgaagcaga
     4141 agaaaaacaa aagagaactg gagaagaaaa acagattctt cagcaagaag tatatcgttt
     4201 tgcggatcat cggcacttag gaaagatgga tacgctcaaa ctcatgaaag aatatggaca
     4261 ggaagtcata gattatcaga aattatatgg cgtatttgag cggaaacata aaagagaaca
     4321 ggaaatacaa gaaaaactac gacaaatcga ccaaaaattt gagtttgtta aagaatggtt
     4381 accgatacaa gataagacaa tttcagaaaa aatggtattg ctttcccgtt ttatacaaga
     4441 gatggaacag atgaaatttg ccagaagcta tcagcaaaat actttattga agcaagaaat
     4501 caatcaattg aaaaagaaac aaaaagtatg gatacaagaa tacagcgaac aattgactca
     4561 agcaggctta tcttatcctt cggaagtacc tgtcttttta caaaaagcca aacaagccga
     4621 acagcagatg aaaagataca atgaattatc ggaaatgctt actccactat ttcctgaaga
     4681 gctgacaaaa gagaaattat ctgtaagact gcgccaactg aaagaaaagc aatcccaact
     4741 ccagcaagaa gaaaaagaag caagtgaaaa tcggcaacga ctccaacttc aagtagaaga
     4801 gttgcaaaga gacggcacat tggacgaact ttatcaacaa gctagccggc aaaaagcaaa
     4861 attacaggaa ttactggagg aatggggagc acttgaaatc gccgggacat tcttaggtga
     4921 tctttcaaca gagatgagtg aaagacaatt accccagttg ttaagagcag caggtgatta
     4981 tttaggtatt ttaacaaaag gaaattatca gaagatatta ctgaaaaatg atacactgac
     5041 tttaacagac ggatatacag aatttcccat ctatgagtta tctacaggta cgaaagatca
     5101 gctgattatg gcgatgagat ttgcttacct ctcattagaa gctaaccgtt cgatatgccc
     5161 gatcatcatt gatgatggct ggcttcatta tgatcatcag cgaaagtatc aattagctga
     5221 acttttagct aaatttggag aaaagtatca aataatttgt ttttcttctg ataaagaaat
     5281 ggtaagctat taccatgaga tgaaccaaat cgtaaaacaa ttagaaggag caaataatga
     5341 aaaaaattcg tgatttagta atcgatgagc agtttgaaca atttgtcctg atcaaaagtg
     5401 cagatgtaag aatcgctaaa aacggaaaaa aatttattgc ttttactttc caagatactt
     5461 caggtactat cgatggtaaa tactgggatg cttcggagga ggaaatcaat aaatttacag
     5521 ccggcacagt cgtttttcta aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa
     5581 agattcttca tatgcgctta acaagggtag atgagccagg agagcctagt ttatacatgg
     5641 aaagagcccc tttgaagaaa gaagaaatgg aagaagaaat caatcaattg ttgtttgaga
     5701 tcaccaatgc gcattggaat cgtattgttc gctatctact taataaatat caaaaacaat
     5761 tttttgagtt tccggcagca aaaagaaacc atcatgcatt tgccagtgga ttagcttatc
     5821 atactttgac aatgcttcac ttagggaaat caatcgccga tgaatatcct gagctgaatc
     5881 gagcattgtt gtatgctggt atcattttgc atgatttagg aaaggtgatt gaactttccg
     5941 gtcctatgtc gacagaatat acgcttgcag gaaatttgat cggtcatctg gtattgattg
     6001 acgaagaaat aactaaagcc tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc
     6061 tcgtattacg tcatatggtt ttagcacacc atggcttatt agaatatggc tcacctgtac
     6121 gtccaagaat aatggaagca gaaatattac atcaaatcga caatatcgat gcttcgatgc
     6181 agatgatgtt gacttcgatt cgtcaaacag aaccaggaaa atacaccgat cggattttcg
     6241 gtatggacaa ccgaagtttc tatgtaccaa aagatttata gcaaaaattt atttttttca
     6301 ttcaaaacaa aaaaagcgag acataagtct tcgctttttt tgttttcttt
//
LOCUS       DAMEEU010000112         6218 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.116, whole genome shotgun sequence.
ACCESSION   DAMEEU010000112 DAMEEU010000000
VERSION     DAMEEU010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6218)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6218)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6218
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.116"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..549
                     /locus_tag="PB779_002651"
     CDS             <1..549
                     /locus_tag="PB779_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740138.1"
                     /translation="IEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFR
                     FEGVTGREISLKDESNTTVSDANILANIILDFIFEHHIPFKEGYEILPANQEYYFYKC
                     ITKRVCCICGKTGADIDHFDKALGRRKRKEVDHSEYTFAALCRIHHTEKHKIGVTNFK
                     NKYQIKGIKLNQETIKKLRIGG"
     gene            552..779
                     /locus_tag="PB779_002652"
     CDS             552..779
                     /locus_tag="PB779_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740139.1"
                     /translation="MINLNAVAFEQTWRTKYKKMSPRDKLFLEIMTFAFIGTQAEQSD
                     ISVEKIKTNRLVNGITETCYQYTIIVVDEEE"
     gene            782..1609
                     /locus_tag="PB779_002653"
     CDS             782..1609
                     /locus_tag="PB779_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replisome organizer"
                     /protein_id="HDE0740140.1"
                     /translation="MAERRMFAKTIIDSDAFLDMPLSTQALYFHLSMRADDDGFINNP
                     KKIQRMVGCGDDDLKLLMAKRFILVFESGVIVIKHWKIHNYIRNDRYKPTLYQDEKAL
                     LADKDNKAYTFAEELSKHDEKLGIPDDNQAVYQMDTQVRLGKDRLGKDSKEIKDLTPS
                     KKSKAKPIRHKYGEYKNVLLSDEQMEKLKTEFPNDYQERIERLSEYCESSGKTYKNYL
                     ATIRSWARKEKSEPKNASSGYKRTGRREKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            1621..1890
                     /locus_tag="PB779_002654"
     CDS             1621..1890
                     /locus_tag="PB779_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740141.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            1896..2060
                     /locus_tag="PB779_002655"
     CDS             1896..2060
                     /locus_tag="PB779_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740142.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            2053..2352
                     /locus_tag="PB779_002656"
     CDS             2053..2352
                     /locus_tag="PB779_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740143.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            2352..2654
                     /locus_tag="PB779_002657"
     CDS             2352..2654
                     /locus_tag="PB779_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HDE0740144.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            2694..3059
                     /locus_tag="PB779_002658"
     CDS             2694..3059
                     /locus_tag="PB779_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740145.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            3549..3689
                     /locus_tag="PB779_002659"
     CDS             3549..3689
                     /locus_tag="PB779_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740146.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            3881..4075
                     /locus_tag="PB779_002660"
     CDS             3881..4075
                     /locus_tag="PB779_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740147.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(4108..4320)
                     /locus_tag="PB779_002661"
     CDS             complement(4108..4320)
                     /locus_tag="PB779_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740148.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            4445..4648
                     /locus_tag="PB779_002662"
     CDS             4445..4648
                     /locus_tag="PB779_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740149.1"
                     /translation="MVKVREQFKIVSDEGNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            4645..4917
                     /locus_tag="PB779_002663"
     CDS             4645..4917
                     /locus_tag="PB779_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HDE0740150.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            4918..5103
                     /locus_tag="PB779_002664"
     CDS             4918..5103
                     /locus_tag="PB779_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740151.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            5090..5437
                     /locus_tag="PB779_002665"
     CDS             5090..5437
                     /locus_tag="PB779_002665"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740152.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            5397..5873
                     /locus_tag="PB779_002666"
     CDS             5397..5873
                     /locus_tag="PB779_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HDE0740153.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(6019..>6218)
                     /locus_tag="PB779_002667"
     CDS             complement(6019..>6218)
                     /locus_tag="PB779_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740154.1"
                     /translation="KLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQFIAA
                     DYDADLADQFINGNNFMPTTN"
BASE COUNT         2275 a          945 c         1295 g         1703 t
ORIGIN      
        1 attgaaattc gttttattga tcctagacgt ttcacagtac agcaacgaaa cttcatctat
       61 gcactcatag gcgatatttt catcgataca ggcatgccaa cggacttctg gaaggaattc
      121 ttttacttcc gtttcgaagg tgtcacaggg cgcgaaataa gcctcaaaga tgaatcgaat
      181 acgactgtga gtgatgccaa tatcttagca aatatcatct tagattttat ctttgaacat
      241 catattcctt tcaaagaagg ctatgagatt ttaccagcga atcaagaata ttacttctac
      301 aaatgcatca caaaaagagt ctgctgtatc tgtggcaaaa caggagctga tatcgatcac
      361 tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcattcaga gtacacattt
      421 gcagcactct gtagaattca tcacacggag aaacacaaaa taggtgtgac caatttcaaa
      481 aataagtatc aaatcaaagg gattaagtta aaccaggaga caatcaagaa attaagaatc
      541 gggggctaat gatgattaat ttaaacgcag tagcgtttga acaaacatgg cgcactaagt
      601 ataaaaaaat gagtccaaga gacaaattgt tcttagaaat catgacattt gctttcattg
      661 gtacacaagc tgaacaaagc gatattagtg ttgaaaaaat taagacgaat agattagtta
      721 atggaattac agagacttgt taccagtaca cgattatcgt cgtggatgag gaggaataat
      781 tttggcagaa agaagaatgt tcgcaaagac aattattgat tctgatgcat tcctagatat
      841 gcctttatcg acacaggcat tatatttcca tctatcaatg cgcgcagatg atgatggatt
      901 tattaataat cccaaaaaaa tacaacgtat ggttggttgt ggtgatgatg atttaaaact
      961 gcttatggca aaaagattca tcttagtttt cgagagcggt gtgatcgtca ttaagcattg
     1021 gaaaatacac aactatattc gtaatgatcg ttacaaaccc acgttatatc aggatgaaaa
     1081 agctttacta gcagacaaag ataacaaagc ttatacattt gcagaagagc tttctaaaca
     1141 tgatgaaaaa cttggtatac cagatgacaa ccaagcggta taccaaatgg atacacaggt
     1201 taggttaggt aaggataggt taggtaagga tagtaaagag ataaaagatt taacgccttc
     1261 gaaaaaatcg aaggctaagc ccatccgtca taaatacgga gagtataaaa atgttctttt
     1321 gtcagatgag cagatggaga aactcaaaac agaattccct aatgattacc aagagcgaat
     1381 cgaacgactg tcagagtatt gtgaatcatc tggtaagact tataaaaact atttggcaac
     1441 tattcgaagt tgggcaagga aagaaaaaag tgaacctaag aacgcaagca gtggatacaa
     1501 gcgcacagga agacgagaga agcttcctga atgggcaatc gaccaagaag cctatctcaa
     1561 gaaaaaagcg ctagaacgag ctaatagaca atcaaaagca ccattctaag aggtggaaaa
     1621 atgaagatcg attatctaga actaattaat gaaatagcga attataaaaa gggcgaggaa
     1681 ttagacgtcc tgagagacgt atatgatcaa ctcgaagaag ctggaattga aggaattaag
     1741 aatgatcgtt cgagttggag taaactcaga tactatttcg cactctatat cgatggaacg
     1801 caattaagaa atttagcata taccaaatta ctattcattg attgtgttaa aggcttgcaa
     1861 aaacatctta atgaacttga gcaggtgtaa acaagatgga cctaaagaca tttacagcac
     1921 agatcgaatt aatgcatcaa gaagctttaa gacaaagtgt gtcgtacgaa gacaagtggc
     1981 tcaacacatt tcatggcgga cgtgagagcg cacttgatca agtactcaaa ttactgaaag
     2041 gagaatgtcg ggatggataa gaaagcggca atgcagcgaa ttatcgaatt gacttattca
     2101 gaagattggc aggaagataa aaaaatagtt gcagaagtcc aaaagctcgg taaatcaatg
     2161 tggactgaaa agcccaaacg gagaacgccg agaaagattg caatctggca tggtgatcga
     2221 attctagtaa cgggtaccgc taaacagtta tctgaaatta ctggtctgag caaaaatatt
     2281 atttgggata gagctaggag cttatggatt gattcaaaag gaagacagtt taggtatgtg
     2341 gaggagaaat aatggacgaa ctaatcgcga aagtagagca gtgggcaaaa gataagggat
     2401 tggatcaagc ggatttcagc aagcaaatgt taaaaacggt cgaagaaatc ggggaagttg
     2461 ccgcttctct agctagaaaa gatgaacatg gtttaagaga cggaattggc gatgtagtag
     2521 taaccttgat catcttggca atgcaaaatg atatggattt atacgagtgc ttggattttg
     2581 cttatgacga aatcaaaggt cggactggaa agatggtcaa tggtgttttc gttaagtcca
     2641 gtgacctgaa ataattccat taatggaaga aataactgaa taggaggata gacatgattg
     2701 atgcaaaaca agtgcaaaaa cagaaagatg gaatgttgat gtttgaagca tatgttctac
     2761 catttcttaa tcaatttgaa gttttggaat gctctgccag cggagaagaa ttggagtatg
     2821 ttgtaattcg tgaaaccaaa gaaaacgttc agaagctaaa cgaatttctt tgcactatta
     2881 actgttggga tatgatagct ccaggatttt tatgtccagc tatgggagaa tttttggaat
     2941 attgtcgtct tgaagatgca ggcactttgg atttagctta tctggtatac aactacctaa
     3001 acatcaacac agatcatttg tggtttggca ctgccgaaag aaaatgggta gtccgctaac
     3061 caccaatatc aatgaaaaaa ggcggtttcc tgaaagtgga attgccgcca ttgctgtaag
     3121 gttctttacg cgactcaagg tcacagaaat ataaatgcaa atctcttttg aagtgatcca
     3181 aagctctcgg aaaatggaag ttttttgttt caaagaataa atgagatttg cgtcaagaac
     3241 ctgagagtta tttccaaaaa agcttccaaa gaaccgaatg agctaaggac atcatgtgta
     3301 aacacataat atagctctcc tttcacggct aatcataaca tgaaaaatat tcgatgtcag
     3361 taggaaaaaa ggtgaattat gaaaagaata ttaaattatc ccggcagtaa cagattctgc
     3421 aattaaactc cgaagctgat gtatcagtat caactgtaga atattatgag cgtggagaaa
     3481 gtcaagcagt cacaaatgta aaaatcgata acgtcaacgg tcttatctgt ttagatgaag
     3541 gcgatagtat gaatgaaatt gctgcagacc atgaattatc agaaactgct ttaattgatc
     3601 aaatcgaatt agctagacaa tactttgttc catatgcaga tacctggtcc aagcataaga
     3661 atgacatcat ttttccagag gaacaatgag agcaactgat ccagtaatta tccttgagga
     3721 agccaaattt atttgaactc acgaagagat agagcaagca cgcttgctct tttctcaagg
     3781 agttaagccg agcaaagtag ctgaaataat gggtcaaaag attcttgatg tcggattgct
     3841 tttgctccat ctagcagaaa aaatttgatt tgaggtgaaa atgatgattc aacttgcagg
     3901 catccaaaca gggaaaattt atttttctgg agaaagcaaa agcgaagcca accaatggct
     3961 attgaaaact tacacgaaca ataagaagct aaggaaaaaa tatcctgatt tgttgctaaa
     4021 ggatgatcag attatgccgg aaccgatgat tttgacccgt aaggagggaa gttgaaacta
     4081 aaaaaccagc cgtgtgggct ggagttgcta tttcttttta ataatgagtt tttctaaatt
     4141 taattcattc tcacgagttt gcgtccaata atcagaataa tattttaatt gtttaagagt
     4201 aggaatgtcg tcttcggtaa aattagaaaa taattctgga gaattatctt tttttaattg
     4261 ttctaatcct gattctttaa aacgttgttc aacgagtttt actaaattgt tgatattcat
     4321 gataaatcac ctttttaaat ttaatttcga tttgattaat cgatacaagt attatatcaa
     4381 ataaaaaagc tgatttaggg ggtcttacaa aaacactaaa attttttcaa aaagaggagg
     4441 aacggtggtg aaagtcagag aacaattcaa gatagtgagc gacgaaggta atgtttacaa
     4501 aataaagatc gttaatatta atgaatatcg agaagcagat cacaaatatt tggttgactt
     4561 atacatgaac gataaatatt tgggagaagg attttgtgga gattcacttt ttgatgatga
     4621 gcgaattttg aaggaggaaa cagaatgatc cacgaactaa aaatactacc agaatatttt
     4681 gaagcagtga cgagcggacg caaacaattc gagatccgca agaatgatcg tgacttcaaa
     4741 gttggtgatc agttaatact acgtgaatat aaaaaataca ttaaacatga attacctgga
     4801 ctaacgagac caacatttag ttacactggt gactcataca aagcagagat cacttatatt
     4861 actgattaca tgcagaagtc cggatatgta gtgttgggga ttaaaggggt gaattaaatg
     4921 aaagtataca tcttagctat cacagagggc acatggatgt tcccagtcgg ttccggaaaa
     4981 atctataaat caaaaacagc tgcttataaa gcatttgaaa aatacaaaaa agaaaacggt
     5041 ggcggcacta acgcaaagat tctagtggct gataactggc atgaagaagg tgaacgtaat
     5101 tgatttacct gttcattttc gtggtactaa ctatttttat gctagtaatc ttattcaaaa
     5161 aaagatgagt aaagacgaac gaaaaattct ggccaacttt tatttagtat taaaaatcga
     5221 acaaaatgtg ttttcggaaa ggagaattgt atgggaaaaa caaaatcaaa gattaagaag
     5281 aaaaaacgac gtttggaaca aaaggcaatc cagaatggaa cggctaagaa aaaataaaaa
     5341 agctacccct ttcgagatag cagcgcaata ctattctacc ataaggggtg gcgtttgtga
     5401 gatttcattg gttaaaagat taccaagaac tagatgagca gattctttac ttaaagtgga
     5461 atcttaataa aagtaagctt gaattgaatc gatgggtctg tggtgattta gcaaacgtcc
     5521 gcatcgaaaa gaattcgaga acttcttctt tagaagagaa tatccaaaag atagaaaatg
     5581 aattggaatt gttgatcgag caaaaagaag aaatgttatt gctgatagat agcttttctg
     5641 gtatcgataa tcaaattgtt aagatgaaat atgttgatca aatgagctta gaagatattg
     5701 ctgaatctgt tgggtatagc tcatcgtatg tcagacagcg acatgcagaa attagaaaga
     5761 cattgaactt tttagatgag tatgaacaca gacaagctga ccgattgaaa aaagaaaacg
     5821 aaattgattt ttacaatagc gagaagtaca aagaacaact ctctttattc taaaattaca
     5881 ctgttcacta aatgttcggt cattgtagct atgtaaacat tgttagcagc atgatattct
     5941 attagtgtca aaaaaatatg aaagagccaa gatatcccaa ccgttttatt aattggtatc
     6001 tgtggctctt ttattctttt aattagtagt tggcataaag ttatttccat ttataaattg
     6061 atcagctaaa tcagcatcat aatcagccgc gataaattgc gctgctgatt taataaatgc
     6121 atccatatca tgaacatctt tattagtatg tctacgaaca tagtgcgttt catcattacc
     6181 aatccaagta gcagctttgg ctaatctttg gagtttag
//
LOCUS       DAMEEU010000113         6183 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.117, whole genome shotgun sequence.
ACCESSION   DAMEEU010000113 DAMEEU010000000
VERSION     DAMEEU010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6183
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.117"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..995
                     /locus_tag="PB779_002668"
     CDS             <1..995
                     /locus_tag="PB779_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HDE0740155.1"
                     /translation="TILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFYMQQEL
                     SNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNVMGTQN
                     VIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIFSCVRF
                     GNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSKFGETY
                     VLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEIERSYE
                     NDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVTW"
     gene            1007..2011
                     /gene="neuB"
                     /locus_tag="PB779_002669"
     CDS             1007..2011
                     /gene="neuB"
                     /locus_tag="PB779_002669"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HDE0740156.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            2008..3156
                     /gene="neuC"
                     /locus_tag="PB779_002670"
     CDS             2008..3156
                     /gene="neuC"
                     /locus_tag="PB779_002670"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HDE0740157.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWVQKQIAY"
     gene            3129..3806
                     /locus_tag="PB779_002671"
     CDS             3129..3806
                     /locus_tag="PB779_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HDE0740158.1"
                     /translation="MGSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            3796..4938
                     /locus_tag="PB779_002672"
     CDS             3796..4938
                     /locus_tag="PB779_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HDE0740159.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            4951..5928
                     /locus_tag="PB779_002673"
     CDS             4951..5928
                     /locus_tag="PB779_002673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HDE0740160.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            5928..>6183
                     /locus_tag="PB779_002674"
     CDS             5928..>6183
                     /locus_tag="PB779_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDE0740161.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDY"
BASE COUNT         2307 a          783 c         1189 g         1904 t
ORIGIN      
        1 aaacaatatt agtaactggc ggaactggtt ccattggaag tgaaattgtt cgtcagcttt
       61 taaaatatga accaaaagct atcagaattt atagtagagg tgaagaaaaa caattttata
      121 tgcaacaaga gctctcaaat cacactaatt tgagattttt aattggtgat atcagagact
      181 ctcaaaggat tgattatgca tgtcgtgatg tggatattat ttttcatgct gccgcaatga
      241 aacacgttcc agcaagtgaa tataatccta tggaagctgt aaaaacaaat gtgatgggaa
      301 ctcaaaatgt aatagatgca gcgatcaaaa ataatgtaaa acattttgta ggtatcagta
      361 cagataaagt agtgagtcct actaacacca tgggtgcgac aaagttattg agtgaaaaat
      421 taataatagc tgccaatcag tataaaggaa aaacagaaac aatattttct tgtgtaaggt
      481 ttggaaatgt catggggtca agtggatctg ttattcctct ttttagtaaa caaataaaaa
      541 acaataaaga tattactttg acagatgttg atatgacacg atttatgatg tcaataccgg
      601 atgctgcaag attagttctg tctgctgcta tgaattcaaa atttggagaa acatatgtct
      661 taaaaatgcc ggcaatcaat attttaactt tagctcaatc attaataaaa atatataatg
      721 atacacatga tgaaaaatat agaggtgaaa taaaagttgt aggtatcagg ccaggagaaa
      781 aattatatga agagctaatg actacagacg aaattgaacg ctcatatgaa aatgataaaa
      841 tgtatatcat tccaccacac tatcatgcta ctgacgaact gtacaaagat tatgaaaaaa
      901 ttaaaatcac tgcatactct tcagatgcaa cagaattaat gagtggacag gaatttatta
      961 gaatcgcaaa agagaataat gtcgtgactt ggtaaggagt tttatgatga aatcagaagt
     1021 atatgtaatt gcagaaattg gtgtaaacca taatggaagt ctagatttag ctttagaaag
     1081 tattgataaa gctaaagaat gtggagctaa cgcggttaaa tttcaaacat ttaaaacgaa
     1141 taagctagtt tccaaaaagg ctccaatggc aaaatatcag aaggataatc ttaaagagga
     1201 cagttctcaa tttgaaatgc taaaaaaatt agaattatct caatctgatt ttattagaat
     1261 aaaagattat tgtatacaaa ataaaattga ttttttgtct actccttttg atgaagaaag
     1321 tgcagacttt ctaaaacaaa ttggtgtaca aggatttaaa attggctcag gagatttaac
     1381 aaatttacct tttcttagaa aaatagatat gtatgggttg ccagttttat tatctacagg
     1441 tatggctgat attcatgagg tcagtgaggc tgtagattgt ttcatagata gtccagttac
     1501 tattttacat tgtacttcaa attatccggc tagttctgaa gatattaatt tattggcgat
     1561 taacacatta aaagaaatgt tcgggatacc cgttgggtac tccgatcatt cattgggata
     1621 tgatgttggt atttgtgctg ttgcgatggg tgctaaggta attgagaaac attttacctt
     1681 ggataaggaa ctacctggtc cagatcataa agcttcttta gatcctcagg aatttgcaga
     1741 ttttgtaaag catattagaa acactgaaat atttttaggt gatggtgtta agcgagcaat
     1801 gccttctgaa cttagtacaa aagaagtatc aagaaaaagc ctagtggtca ctgagaattt
     1861 aaatgtggga gatattctta cagagaaatc tcttacaata aaacgtcctg gaaatggaat
     1921 agctcctaag tttttatatc aatatattgg caaaaaagtt aaaagaccaa taagtgcaga
     1981 tagtgttctg cttgaggaag atgttgaatg aaaaaaatac ttatagtaag tggaacacga
     2041 gctgattatg gaatatataa acctgttgct gagaatttac tacaagataa ttgggatgta
     2101 tcatttgttg tttctggaat gcatttatcc cataaatatg gatttactaa agaattgatc
     2161 ttagctgacg gatttagaat tagtggagaa gttcaaagtt tgtttttaga gaacaataag
     2221 ggaaacatgg ctcggtctgt ggcattagag ataaatggtt tcacaaatat atttgaacaa
     2281 actagccctg attttgtatt attactaggg gatagaggag aaatgttggc agctgcgata
     2341 gcttgtttgt atcttggaat caaaacagca catattcacg gaggcgaagt gtctggtact
     2401 gtagatgaat caataagaca tgccataacg aaaatagcat ctgttcattt tgctgctacg
     2461 gaaaaaagca aagagcgttt aataaaaatg ggggaagatt cttggagagt ttttcccgtc
     2521 ggagctccta gaatagatac tattttaaat aatagattac ctagttttag agatataaaa
     2581 gaaaaatatc atctaaaatt tgaaaagaaa aaatacgttt tgcaagtatt tcatccagtt
     2641 gtaaccgaac tagaaaatat agaaaaacaa attttagctt tgatcaattc aatggaacaa
     2701 caatctcaac caattatttg cattttacct aatagtgatg ctggtagcga aattatcaga
     2761 aaaatgtacc agaaatattt aaaaacggat attatttata ttacgaattt agagccggag
     2821 gaatacctga ctatattaaa agagtgcaaa tttatgatcg gaaattcttc ttctgggata
     2881 attgaagctg catcattcaa aataccagta ataaatttag gaaccagaca aaatggacga
     2941 gaacaatcta aaaatattat aaatgcaaat ctaaatgaaa atgaaattga aactgctttg
     3001 aataaaatac aagatcctca gtttataaaa agcttgaaaa atgttaagaa catctacggt
     3061 gacggcaaca gttctagaag aataacaaaa acattgaatc aaatattgaa tgatggggaa
     3121 gatattaagt gggttcaaaa acaaatagct tattaaaata tactagtgat ccatacatta
     3181 ttattggggc tggcggacac gcaaaagtca ttattgaaac cttaagatta gaaaataagt
     3241 taatatatgg attttttgat gataagcaaa ataaaatgca agatctgaaa tatcttggga
     3301 aaataaacga attgaatagc tgggcggata gcaaaaaaaa aatctataaa tttattgtag
     3361 ctattggtga ctgtgtagta agaaaaaaga ttataaaaaa attgaatatg ccaagtgagc
     3421 aatatggaat agctgttcat ccaagtgcta tagtggcaaa agaaatttca attggttatg
     3481 gaactgttat ttttgcgaat gctgtaatta acccagatgc tgtaattgga gagcatgcta
     3541 taataaacac aggtagcatt gttgagcatg attgtagaat taataactat gttcatttat
     3601 ctccaggtgt atgcttagcg ggtggagtac atgtaggtgt aggaactcaa ataggaattg
     3661 gttctcaatg tatccagatg aagaaaattg gatcttggtg tatgataggc gcagggagca
     3721 ctattgttaa ggatattccc tcacattcct tagcttatgg caatccagct aaaattaaga
     3781 aagaaggaat taattttgaa ttctagaatt ttattatcaa gtcctcatat gggaggaaca
     3841 gaagaaaaat atgttgctaa ggcttttaaa gataattgga tagcgccatt aggtgaaaat
     3901 gtggataaat ttgaagaaag tattacaaaa tatactggtt ctaagggcgg agcttctgcg
     3961 ttaagttcag gtacagctgc catacatctt gccttaagac tgcttaatgt tggaaaaaac
     4021 gatattgtct ttgctccttc atttactttt atagctacag taaatcctat tttatatcaa
     4081 ggggctgtac cagtgttcat tgactcagaa cctaatacat ggaatatgag ccctgttgca
     4141 ctagagagcg cattagaaga agctgaaaga aacaaccaat tacctaaggc aatcatcgta
     4201 gtgaatttat atggtcaaat ggctgattat gaacgaattt tagctattgc aaaccaattt
     4261 aatgttccag tgatagaaga tgcagcggaa tcgttaggtt ctacttataa gggaatttcg
     4321 tcaggcttat ttgggacaat tgggatctat tcatttaacg gtaataagat catcacaacc
     4381 tcaggtggag gagctctagt gtctagtgat aaaaaatatg ttgagcattc aagattttta
     4441 gcaacacaag caagagatca agcaccgtat tatcaacata gcgaaatagg ttataattac
     4501 cgtctaagca atatttctgc cggtatcgga cgtggacaaa tggaagtatt gaatgataga
     4561 gtagctaaac gaagagaaat tttcaatcga tataaggaag ctttttctgg aattgataga
     4621 attgaaatga tgccagaagt ggatggcatg gtgccaaatc gttggttgtc tactttaacg
     4681 atcaatgatt ataattctat tgatcaagta gttaacgtaa taaataaact aaatgaaaaa
     4741 aacattgaaa caagagcttt gtggaaacca ctacatttgc aaccagtatt tcaaggggta
     4801 aaaatgtatt accatgataa taatcttagt gtgtcagaaa agttatttaa tagcggctta
     4861 tgcttacctt ctggaagtaa tatgacagat agtgaacaag aatttgttat tgatgagttt
     4921 aaaaaaatat tcaagtaggt gtgatatttt atgaacatag gaattattgg tttaggttcc
     4981 atggggaaaa gaagacttag actcattcaa gaacacttta atgatatttt actatgtggt
     5041 gttgatacta atgaggcgag acgaaaggaa gttgaaaagg aatttggaat accaacttat
     5101 aatagtctaa cagaggcaaa aaatttgttt gaaataaatt cagtttttgt ttgtacatcc
     5161 cctataaccc atgaatttat tataaaagag gctttaaatt tagattgtaa tatctttacg
     5221 gaaatcaatt tattaaatga atattatgat gaaataatcg aagtagctaa aaagaaagat
     5281 agattacttt atctatcttc tacatttttg aagagaaaag aaattcaata tattaagtct
     5341 aaagtgacgc ataataaaaa aatttcttat caataccatg taggacagta tttacccgac
     5401 tggcatcctt gggaagatta tcgcaatttt tttgtttcaa acaaaaaaac taatgggtgt
     5461 agagaaatat tcgctattga attaccttgg attatagata catttgggaa agttaaatcg
     5521 tttactgtaa tgacccagaa attatccaat cttgatattg attattcgga cagtttcact
     5581 cttattattg agcatgaaac tggtatagtt ggaactttaa gtgtagatgt tgtttcaaga
     5641 gtagctaaaa gaaatttaac tataattggt gaaaagattt taatagaatg ggaaggtaac
     5701 ccggattctc tattttcatg gaatgaagaa acttctagta tgacagatat tcaattgtac
     5761 gatgaggtta tgcatgataa taattattca catactatta ttgaagatgc atatttagag
     5821 gagattaaag aatttttcac gcttttggaa aagaaaatgg aaccccaata tacttttgaa
     5881 aaagataagt atattattaa cttaattaac gacattgagg taaattaatg atgaaagtaa
     5941 ttttttttgg gttagggtca attggaaaga gacatctaaa aaatctaata agctatggaa
     6001 aaaagaattc tattaatttt gatataacag cttatagtag cagtggaaaa aaagagtttg
     6061 aagaaataac gtatattcaa aatagagacg atttggatac acattatgat atagctttta
     6121 ttacaaatcc gacttttaag catctggaaa cactaaatgt aattgttgaa aaagttgatt
     6181 aca
//
LOCUS       DAMEEU010000114         6067 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.118, whole genome shotgun sequence.
ACCESSION   DAMEEU010000114 DAMEEU010000000
VERSION     DAMEEU010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 6067)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6067)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6067
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.118"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(173..475)
                     /locus_tag="PB779_002675"
     CDS             complement(173..475)
                     /locus_tag="PB779_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740162.1"
                     /translation="MLMEGKTQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINL
                     YYSNKNYFKIPATKTRMKKDVYFLFDIVTDVPDARSDHRRYDYLKYTFVDPERYKD"
     gene            complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="PB779_002676"
     tmRNA           complement(695..1061)
                     /gene="ssrA"
                     /locus_tag="PB779_002676"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1232..2005)
                     /locus_tag="PB779_002677"
     CDS             complement(1232..2005)
                     /locus_tag="PB779_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HDE0740163.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGTGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2149..2499
                     /locus_tag="PB779_002678"
     CDS             2149..2499
                     /locus_tag="PB779_002678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDE0740164.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2480..3196
                     /locus_tag="PB779_002679"
     CDS             2480..3196
                     /locus_tag="PB779_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0740165.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3196..4644
                     /locus_tag="PB779_002680"
     CDS             3196..4644
                     /locus_tag="PB779_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0740166.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
     gene            complement(4714..5223)
                     /locus_tag="PB779_002681"
     CDS             complement(4714..5223)
                     /locus_tag="PB779_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740167.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(5213..5938)
                     /locus_tag="PB779_002682"
     CDS             complement(5213..5938)
                     /locus_tag="PB779_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740168.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
BASE COUNT         2068 a         1050 c         1169 g         1780 t
ORIGIN      
        1 cttataattg gagtggtagt taattagtga cttatttttg attttatagc actgatacta
       61 taaaatatag atatcatcat attacacaat cttaatacta acttaaaaaa tatccctttt
      121 ataagtatgg tgataaaatc cgttccgggc tacctttttt aggtagccta ctttaatctt
      181 tatacctttc tggatcaacg aaagtatact tcaaatagtc ataacgccga tgatcgctcc
      241 gtgcgtctgg cacatcagtc acgatatcaa acaaaaaata cacatctttc ttcattctgg
      301 tttttgttgc cggaatttta aagtagttct tattagagta atagagattg attaataagc
      361 tatcttcgat tgctaaaaag aaaacttctg aatcccacac cttataaaaa tctttgacaa
      421 atctattcga aggatcaaat ttaaaccata attgtgtttt tccttccatc aacataatgt
      481 tcacctcaaa aagagtatac gaactaatgt tctttttgta aagtaggaat atcattgata
      541 atatggatgg aacatatata ttaaaaagtg ttctttttga atgctatttt gaatgccatt
      601 ttcattcatt taacgaaaat ctgcgaaaat aaaaaatgct caaaccctta taaaataagg
      661 atttaagcat ctagcgaaat ctgctgaaat ctcacaatgg agacggcggg agtcgaaccc
      721 gcgtccaaac acatcgccac ttaaaaatct acgttcatag tcaactcatt taaggattca
      781 ctttacagct tgccgagtga caggcattct gtatcgctag tctgatgttc tctttttcaa
      841 cttacagacg gaaagttgaa acgtatccca ctaaagttag gacccttact cgagcacatg
      901 ggcgatgccg agaggatcta cgctaactgt ttttaggcag ctaaagcgta agagttgttt
      961 tcgtttttag cagttatatt taactgtaac gtttttacgt agacgtaacc tacgaaacgc
     1021 aattcaagct cgactgtgcc tgtcgaatcc gtaacgtccc cgttagctaa caagggttac
     1081 gtgtattttt catacaaaat tagtatagca tatattggga taaattcaat aaaaaagcga
     1141 atcatatccc attatttata taataactgc ccctttctta agaaaaaata agcgattttc
     1201 ttaagaaaag aggtagcttc aaaaaaagat cttaaatcag atcaaaatac ttcaatgcgt
     1261 ggacaattcc gccttctgta tttttctttg tgataaaggt agaaagttct tttaatccgt
     1321 cataggcgtt gcccatagcg attttgttgt cgcaagcttc caacaaggca aaatcattcg
     1381 gaccatcgcc aaatccaaaa gtaggaactt tttccagctg aagttctttt tgcagacgtt
     1441 tgacacctgt cccttttgag attcctttct tcactgtatc gatcgagtaa ggaccattcc
     1501 gataaaaagt tagctcagga aaatgttcgt gatagtattc gtcacctgat tgagataaga
     1561 tcagcaacat atttactgtg ttttctttaa agcctaaagg atcaatttcc ggaacatctg
     1621 aatgaatgaa gtcgtaagca ttgatcattg tttggctatg accggtacac cagattttct
     1681 gatcgttata gtaagaaagt tcatgaccgt tcaactgtac atgatcatac attttttgac
     1741 attcttctga agaaaatgtt tgagaataga tttcttcgcc gtctactcga atgaaagaac
     1801 cattcatggt gaccgcagaa gtaatgcccg catcttccat gatagagtgg atttctgctt
     1861 ctgtacgtcc tgtagcgatg acggggagaa cattgttttc ttttaatgcg ttcatagctt
     1921 ttgccacttc gggtgtgatt tttgatttcg catctagtaa tgttccatca agatcaaaga
     1981 aagtgattgc acgataattt gacacaaata aaactccttt tttattggaa taagtttatc
     2041 ttaacaaaga atgaacaaaa gacaaacctt tcgtgaagaa ttcctgaaca tattggttca
     2101 gtcaacaatt tagagtatac tataagaaga gaatttagga gggaaagaat gatttttttc
     2161 agtattggta tcttattctt aataattggc agtctttttc ggattctgcc ctcaaaagga
     2221 aatctgcctt tttatgggta tcattcgcct cttgccgcaa aaacagacgc tcattggcgg
     2281 ctggctcaaa agacaagcgg aaactggttt tttcttatgg gcttactgat ggcattgatc
     2341 ggctattatt taaagacatc tgggcatacg aattattttc tgattgaaat gcttctgcta
     2401 gtatttccaa ttatgcctat ttttattatg acagaaaaga aattacagaa atatgacctg
     2461 gaaactggag ggaacgataa tgaatatttt aatgattgaa gataatcaat ctgtttctga
     2521 aatgatgcag atgtttttct taaatgaagg ttgggaagca actttcaagt atgatggaaa
     2581 agaagggctc gatgcctttt tagaaaaccc acaacattgg gatatgatta cactagacct
     2641 gaatttgccc acactggacg gtatgctagt aggaagagag atccgcaaag tttcaagtac
     2701 tgtgccgatt atcatgctga cagctagaga ttctgaaagc gatcaggtga tcggcttaga
     2761 gatgggggca gatgattatg tcacaaaacc tttcagtcct ctgacgctta ttgctcgaat
     2821 gaaagctttg catcgccgta gtgagttggc agaagcaaga gaagaagcag tagtttcaga
     2881 tgatcatttt gatatcgaga ctagtcattt caagatgaat acgaaaacac gagaagcgta
     2941 tctggacaac cggccaattg aaggactgac gcctaaagag ttcgatctat tgtttacttt
     3001 agcaaaaaaa ccacgtcaag tattctctcg ggagcagttg cttgaattag tctgggatta
     3061 tcagtacttt ggtgatgaac ggacagtgga cgcccatatc aagaaattac gacaaaaaat
     3121 cgaaaaggtc ggaccacaag tcatccaaac tgtttgggga gtcggctaca aattcgatga
     3181 ttctggtgtt gcctaatgcg ttatttgtat cagcaactct tagctttctg cggaatggtc
     3241 gcgttgatct tattgatcgt tggagtttct tttacacaac tgacaaaaca aacgattgaa
     3301 gaaaacaatt accagcaact gtttggatat gctgaatcag ttgaaaagac aacgcaaacc
     3361 tatgccgata cgctcccgca gtttagtcaa gatcaggcgt ttcaaaatgc attgctgctg
     3421 acagagcaag tactgacaga acaaaatgtg aactttatat ttatcgataa aaacgaacgt
     3481 gtcatttatc cgactaatac agctttactg aattttacct taacagctga tcaatggaaa
     3541 aatctgagga atggacgtca agaaaaattc acatcgaata aaaatatttt aggacaagca
     3601 caggcgacct cttacgcact tgtgccattt aatttgaatc atgaattcta tggagcactt
     3661 gtagttagtc aacctgcgcg aaatatcgat aacagcgttc gtccaattac actgaacctg
     3721 ttcaaaggat ttattttttc cagtatcgtt gcagttattg ccagctatgc ttttgcagca
     3781 ttccaagtta agcgtatcaa tcggttaagg aatgcgacga aagaagtgac gaatggtaat
     3841 tttgatgtac agctccccgt acatgacaaa gatgaatttg atgagttagc agatgatttc
     3901 aataaaatga cgaattcatt gaaagaatct caagcagaaa ttgaagaaca agaaaatcgt
     3961 cgaagacaat ttatggcaga tgcttctcac gagatgagaa cacctcttac gacaatcaac
     4021 ggacttctgg aagggttaga atacaatgca atccctgaaa atcagcgaga aaacgcgatt
     4081 aaattgatga aaaatgaaac agagcgtctg atccgtttgg tgaatgaaaa cttggattat
     4141 gaaaaaatcc gtacgaatca aatcagtatg gtcattaaaa aattcaatgg aacagaaaca
     4201 ttgaaaaata ttgttgcaca gttagaagct aaagcagaag cagcaggaga tacattgaca
     4261 ttgaaagccg ttgatgatat tgatgtttac gctgattatg accgatttgt ccaaatcatg
     4321 gtcaatatta ttcaaaacgc gatacagttt actgaaaacg gccaaatcac gattacttta
     4381 gaaaaaggct atcttgaaac gatcatcacg attgaagata cgggaattgg aatgtctgaa
     4441 caacaaatga aaagtatctg ggatcgttat tataaagtag atccttcaag aaaaaataca
     4501 aaatatggtg aatcaggatt aggtttacca atcgtgcagc aacttgtacg cttgcataaa
     4561 ggaaaattag aagtagaaag cgaactagga aaaggaacaa aattcgctgt tcgtttgcct
     4621 gacgtagaaa tcaaaaaaga gtaaaaaaca agcggtataa aagatcatga atcgatcttc
     4681 tataccgctt gtttttacta taaaatgatt gatttagccc gcgggctcta aacgatcaat
     4741 ataaggactt tgagcaatag tagcatcatg agtaaagagt aagatacctt gattttcttc
     4801 atgagctaaa taagaaagca agtggagtag ctcttggatc tccaatacac taagttcatc
     4861 aaatgtatct tcaataacaa tattgtttcg cttggaaagc aaggcatgaa gtaattgcag
     4921 ctttactttt tcaaaagacg tcaactcagc tgccgcacaa ttaagcaagg aaggagagat
     4981 atcaagtttt tcttgatagg ccaaacgatc ttgtttgatt tctttttccg gtacatccaa
     5041 caggacatgg tctttaagat tcagataagg aaacatcggc caattttttt ggatgatcgc
     5101 aaaattatcc agttttgcaa caagaacctc ttttttcaag tgctccaata ttttatgctg
     5161 tttttcgaga ggacacaaaa taacggtcaa gtgttcagca tgaatcaaat attcaggttt
     5221 cattacgtcc aggcctccta ctttgcaaat gatggataaa aaaagtgaaa gggaatagac
     5281 taagaatgag acagcatcca ctgagcccaa taagagtttg ggcaaatccc ttaagtatat
     5341 ctgtgaaaaa aagatcattt tggaaatcga tggtaaaaaa agtctgttga tccatcggaa
     5401 ttgtaagtcc gcttaccgaa gtcaagatat cacggatatc tggcagttca gtagtcttta
     5461 agacaagaaa attgatcctt tgaagaagcg cttcataaac tgactggaag cttacgatcc
     5521 acaataaaac caagatacaa caaagaaaga gaggaaagaa cagctgccag aaaataaaaa
     5581 ggaataattt ggttttagaa agaccagtca ggtgccaatt gatcaattcc tgcttgtttt
     5641 gcctgactga atagtaaaag aaaaagataa aaaggaaggc aaatagaaaa aataaactga
     5701 atatgccttt tatataaaat cggctagcta attctaaagc cggaagaagc tctgtagatg
     5761 cagaagcgcc aataaatgaa agccgatctt ggacttgatt ggctaaagcc gattgcaaat
     5821 ggtaaagagt caggcatgct atcaataaaa aagcagaaaa gcttgaaaat aaacaataga
     5881 gtattgtctg ctttttgtaa taaattaatc gagcagtagc atagcggatt attttcatac
     5941 ttttcacctc tataaaaagt atagaaaatg aatatgaata aagtatgaaa ttcctttagt
     6001 gaaatcacga attaaaacca gaaaatattt tgtaaaaagc aagaggttgt gaagaagctg
     6061 ccctatt
//
LOCUS       DAMEEU010000115         5874 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.119, whole genome shotgun sequence.
ACCESSION   DAMEEU010000115 DAMEEU010000000
VERSION     DAMEEU010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5874
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.119"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            641..1375
                     /locus_tag="PB779_002683"
     CDS             641..1375
                     /locus_tag="PB779_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HDE0740169.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1391..2560
                     /locus_tag="PB779_002684"
     CDS             1391..2560
                     /locus_tag="PB779_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HDE0740170.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2576..3571
                     /gene="lacD"
                     /locus_tag="PB779_002685"
     CDS             2576..3571
                     /gene="lacD"
                     /locus_tag="PB779_002685"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HDE0740171.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3650..4576
                     /locus_tag="PB779_002686"
     CDS             3650..4576
                     /locus_tag="PB779_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HDE0740172.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4595..5845
                     /locus_tag="PB779_002687"
     CDS             4595..5845
                     /locus_tag="PB779_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HDE0740173.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1966 a          955 c         1203 g         1750 t
ORIGIN      
        1 gtttgaaaaa tgctatttcg aggtagaagg atattatata agcacggttg actaaacgaa
       61 gtgataataa aaaaagttat tcaagaataa gaaaaattat gatacgaatt cagataaact
      121 ggagaataca gagaccttta aaagggataa gaaacaacat aaattcctct taagagagaa
      181 cgaaaggaca aagccagcaa cttgatacac gagctagtat tagaggaatt tattctcata
      241 gactcccttt tgaatacgtt tcaactttaa ttttcatgtt cataaatgat ttgaaaccaa
      301 agcaaatgcg ttgcactttt cctccgtctt ccgaaaatcg ttcaattcac tggtaagtag
      361 tcatttgata gtttgaggca aattgttgat tgatgaaggg taggagctaa aaaaagatac
      421 cagttgaaga gagaaaaaga aaaaaataga gggtgttctt gaatgaaaaa agttggaaaa
      481 ttatttttca tttcctttta ttcctattaa agtcagtgat gtcaatcata ttaacaagac
      541 taaaaatgaa aataaaaaaa agattgttct tagtattgac tcataaaaaa taccactact
      601 atacttacat tgtggttata gccagttagg agagacatcg atgcaaaata cctttcaatc
      661 aaaatcactt tattatcagc tggtagaaat attgaaacaa cgaatcgaaa acagtatggt
      721 cgctcatgac aagctgccat cagaaagaga gttgaccagt ttttatggcg ttagtcgcac
      781 gacggtgcga ctagcattgc aagaactgga aaaaatgggc tacatttatc gacaacatgg
      841 aaaaggaacc tttgtttcgg aattaaggac aaatgcgact gatctagctg gcgcatatag
      901 ttttaccgaa caaatgcggg caatgggcaa acatcctgaa accaagatat tggccttcaa
      961 gaagattgaa gcaactaaat atttagcgag tcatctgaat gttcaactag gtgagccttt
     1021 atttcaatta gaccgattgc gcttagctga tgatttgcca atgatgatcg agaaatccta
     1081 tttgccagtg aagctattta tgtccctttc tcaagaaatt ctatttctga aacctttata
     1141 taatttgttt tcagagaatt tcaatcaaat cgtacggttg gctgacgagg aattttatgc
     1201 cagcattgtc cagaaagaag atagtgagtt gctaaatatt ccagaaggat caccagtgct
     1261 ccatttagtt cgctcaacct ataatctcga gaacgaagtg attgaattta cattaagtgt
     1321 agcgcgggct gataaatttc attataagat caggcatctg cgttccacta actgaattgg
     1381 aggaaagaaa atgtttatgt tctcaaaaga agaactacga aagctaggag cagaaaatac
     1441 tacccgagaa attcgacagc aaccggaact gtggcatgag acgtttgacc gttatcaaga
     1501 aacagttgca gatttagatc gtttgtttac ggatgcgaaa caacatgctg gagagcgacc
     1561 aatccgagtc atttttacag gggccggaac ctcgcaatat gtgggagata cactaattcc
     1621 gtttcttact agtcaaggaa atacgaacca gtttattttt caaagtattg gttcgaccga
     1681 tatcgttgct acgccaaaag aatacctgat tcctgatgag acaacgatct tggtctcatt
     1741 tgcccgtagt ggaaatagtc cagaaagtct agccgcagtt aagatggcca atcagctggt
     1801 caacaagatc tatcatatcg tgatcacctg tgcaccagac ggattattgg ctacacaaat
     1861 gcctacaaaa aaagaaaatc tagttttact aatgccaaac aaagccaatg acgctggttt
     1921 tgctatgaca agcagtttca gctgtatgac gctgactgcg ctacttattt ttgatcaagc
     1981 aagcaatcag caaaaagaaa gatatgttca tcaattaagc cgactaggag aagaagtcat
     2041 ccaacgagaa tcagagatcc aagggtatct ggcatcagac tttcatcgca tcatttactt
     2101 aggttcggga agcttaggcg gattgactag agaagcgcaa ttaaaagttc tcgagttaac
     2161 tgctggaaaa atcgcaaccg tatttgatac atctttagga ttcagacatg gtcccaaatc
     2221 ttttgtcaat gagcaaacat tggttttcct gtttgtcagc aatgactcat atacgcagaa
     2281 atacgatgta gacatgctgg aagaaatcaa aaatgacggt attgcccaac gcgttgttgg
     2341 aattggtcaa aagggttcat tgtttagtgg tgattccttt gaattagttg cagattcgtt
     2401 actgccggat ggctatcttg ctttagcaga tatcatggta gcccaaacga tcgcattact
     2461 ttgttcggtg aaggttggta atacaccaga tacaccatcg ccaagtggaa cagtcaatcg
     2521 tgtggtcaaa ggcgtaacga tttatccata tgaaaaatag gaaagagtgt gaagcatgtt
     2581 agaatggtcg gaaaataaaa gacaagcaat ggaacgtcta tcgacgccag aaggcattat
     2641 taccgctttg gcgatcgatc agcgaggcgc gctgaagaaa atgatgtcgg ctttagggat
     2701 ggaagcgaca aaggaaaaaa ttgagcagtt taaaacacta atttcccaag aattgactcc
     2761 ttatgcctca gcaattttat tggatcctga atacggactg cctgctgcac agaagcgtgc
     2821 agcagcgagc ggtctgctgt tggcatatga aaaaactggt tatgatcaaa ccgtacccgg
     2881 ccgcttgccg gatctgctgt cggactgttc agttctgcga ttgaaagagt taggtgcgga
     2941 tgcggtgaaa tttttactgt attacgatta tgaagaagca gaggaaatca atcggcaaaa
     3001 gcaagttttt gttgaacgaa ttggaagcga atgcatggct gaaggactgc cattttattt
     3061 agagttattg tcatatgatg ctaaaaatgt agatacgaaa tcgctttcct atgccaaagc
     3121 aaaaccgcgc aaagtgatcg aaatgatgaa agaattctcg aaaacccagt ataaagtaga
     3181 tgtcttaaag gttgaagtac cagtaaacat gtcatttgtt gaaggaaatg caacagggga
     3241 gatcgcctat acacgtcaag aagctgccgc ttattttaaa gaacaaagcg atgcaacaga
     3301 tttgccgtat atcttcttaa gtgctggggt atcagcggca ttattcatgg agacattgcg
     3361 ttttgccaaa catgctgggg cacgattcaa cggtgtactc tgtggcagag caacttggaa
     3421 agatgcagtc gctcctttcg ttgaaaaagg agaagcggca actttagaat ggctgacaga
     3481 acaagggaca caaaacattc gtcaattgaa tgaagtgata agagaaactg ccatcccatg
     3541 gtatgagaaa gtaagtgaaa gcacttgtta atgtttctaa tatattagta gtgataagag
     3601 atatgtgtga ttataattta tcattattga aactgggagg atattttata tgaataaaag
     3661 attgttagat tattcagctt cagatttttt gaaagctaag ccgatggaat taaagcaggc
     3721 aattttggct tctgaaggta gaacaattat ggcagaaaat gtgccaagta gctgtcctta
     3781 catgggaaaa tcagtgacaa atgcagaatt ggagagagct gctggagctg atttaatttt
     3841 gtttaatgca ctagatcttt ttaatcctca aatttcaggt gtacctttaa ctctaaaaga
     3901 gaatccaata atctggatta aaaaagcttt aggaagagct attggtgtaa atttagaacc
     3961 tgtagacaaa gaagttttga tgagtgaaaa tcgaactgaa atttcaagtg gtagaatcgt
     4021 ttctcctgag actttaaaaa aggcaaatga attaggcttt aattttattt gtttaactgg
     4081 aaatccagga acaggagtat ctaatagaac tattgagaaa gcaataacat tatccaaatc
     4141 aatttttaat ggattaatta tcgctggaaa aatgcatggt gctggtgttg atgaaccaat
     4201 tatgaactta gatatagcaa aaagatttat taaaacaggt gtagatattt tattagttcc
     4261 tgctccatac actgttccgt atttcatgga aagtgatttg cgaggaatcg ttgattatat
     4321 aaaagatttt aatagaaata aatctattga ggaaaaagtt ctagtactaa cggctaatgg
     4381 aacaagccaa gactcttctg accaagaaac tattaaaaaa attgcattag catcaaaagc
     4441 atgtggagct gatattcaac acatagggga ttctttaaat ggtatttgtc ttccagaaaa
     4501 tatttttgct ttgggtcaag caattcgggg atatcgtcat caaattatta tgttaggaaa
     4561 atctaattat cgttaattaa ggaggaaatg aaagatgatc gacaaagttc aaaaaatagc
     4621 tgcaaaaatt agtaatcaaa gacatctact agctttaaga gacagcatgg ctgcagttat
     4681 gccattaatc attattggtt ccttttttat gttattagca aatttcccga tagaaggatt
     4741 tacaaaatgg ttatctgaaa ttggagtaca atcctttttg aacaaagcat cagattcaac
     4801 atttggtatt attggattag ctgttaccta ctctttggga cacaatctag caaagactta
     4861 tggtgtagac tcattatcag caggattatt atctttgagt ggatatgttt tacttacacc
     4921 tttattggat gcagatggtt ctataggatt tccaacaaaa tactttggta cctcgggtct
     4981 ttttgttggt attattgtag cacttgtatc tacagaaatt ttccggtggt ttgtacttaa
     5041 aaatattaca attaaaatgc cggcaagcgt tccaccaaat gtaagccgag ctttcgttgc
     5101 tattattcct ggcttttttg tcgttctact atggtttatt gttgttgtaa tttgttataa
     5161 acttggaatt gaaaatgttc atgctcttat tgcagataca ctcgcaaaac cactatcttt
     5221 actgacgaaa actttaccag gaattatatt ggttatactt attcaatgtt tcttttggat
     5281 gtttggtatt catggtgcac aggtaacggg gccaataatt gaaccgttat tattgcaaaa
     5341 ctctgatgta aatagaattg cttatcaagc tggaaaagaa cttcctaaca ttataactta
     5401 tgaattctta tataactttg ttttttctgg tggtgcaggt tgtttatttg cacttgccat
     5461 tttaacattt ttcttttcaa agagtcagga aaataaaact ttaggtaagt tatcaatcgc
     5521 tccagtaagt tttcaagtag cagagcccct tctatttggg tttccaacta tattaaatat
     5581 aaaaatgtta attccatttg taactgcacc agtagtaaca acattaatta cttatttttc
     5641 aatgagtatg ggattagttg caaaacctgt aggagcaaca atcccatgga caactccacc
     5701 gataattgcc ggatttttag cttctggtgg acgaataagt ggtgcagtga ttcaagtaat
     5761 aacaattgca ataaatgttt tgatatacta tccattcttt aaattagatg ataatgccaa
     5821 gctaaaaagc gaaaaaaatg attagaacta cctatatgtt tctaactgta gtta
//
LOCUS       DAMEEU010000116         5532 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.120, whole genome shotgun sequence.
ACCESSION   DAMEEU010000116 DAMEEU010000000
VERSION     DAMEEU010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5532
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.120"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(79..717)
                     /locus_tag="PB779_002688"
     CDS             complement(79..717)
                     /locus_tag="PB779_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HDE0740174.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNSISDINLIYSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPV
                     QAEQPVVQETVQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTAT
                     NGRYIGRYQLDSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
     gene            1052..1486
                     /locus_tag="PB779_002689"
     CDS             1052..1486
                     /locus_tag="PB779_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HDE0740175.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
     gene            1509..1829
                     /locus_tag="PB779_002690"
     CDS             1509..1829
                     /locus_tag="PB779_002690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740176.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            1970..2161
                     /locus_tag="PB779_002691"
     CDS             1970..2161
                     /locus_tag="PB779_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740177.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(2232..2489)
                     /locus_tag="PB779_002692"
     CDS             complement(2232..2489)
                     /locus_tag="PB779_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HDE0740178.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            2647..2910
                     /locus_tag="PB779_002693"
     CDS             2647..2910
                     /locus_tag="PB779_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740179.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            2934..3122
                     /locus_tag="PB779_002694"
     CDS             2934..3122
                     /locus_tag="PB779_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740180.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(3205..3390)
                     /locus_tag="PB779_002695"
     CDS             complement(3205..3390)
                     /locus_tag="PB779_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740181.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            3605..3976
                     /locus_tag="PB779_002696"
     CDS             3605..3976
                     /locus_tag="PB779_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HDE0740182.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            complement(4126..4198)
                     /locus_tag="PB779_002697"
     tRNA            complement(4126..4198)
                     /locus_tag="PB779_002697"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4163..4165),aa:Gln,seq:ctg)
     gene            complement(4244..4672)
                     /locus_tag="PB779_002698"
     CDS             complement(4244..4672)
                     /locus_tag="PB779_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740183.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            complement(4732..5490)
                     /locus_tag="PB779_002699"
     CDS             complement(4732..5490)
                     /locus_tag="PB779_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HDE0740184.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
BASE COUNT         1869 a          888 c         1102 g         1673 t
ORIGIN      
        1 aaagaggtca tgcgaaagaa taaatcgcat gacctcttac tatattttga atgtgtttaa
       61 acgttcaaat aatgaatctt agtaccaacc gtttgcttcc cagaatgctt tcgccgcttc
      121 ccaagaacca taacgtgaag taacatattg ttctgctact ctttcttggt ttgcagcaga
      181 gtagtcacca tttaagtaag aagaatctaa ttggtaacgg ccgatgtaac gtccgttcgt
      241 tgctgtgtaa gaaccgcttg attctttttg tgcgatccat tcttttgcag agcttgtact
      301 tgctggagta gcagcagttt ctgttacagc aggagcaggt tgtgtttcag caacaggcgc
      361 tgcttgtgtt tccgtttgaa ccgtttcttg tacaacaggt tgttcagctt gaacaggttc
      421 agcttggact ggtgcttctt gaacggctgc ttgaggttca gcagctgctt gtgcagagcc
      481 ttctgttggg attgttaatt gttgtcctga gtagatcagg ttaatatcag aaattgaatt
      541 tgattctgca atggcattga tcaaggagtt atcaccaacg tatttttgag aaatcgttga
      601 tagagtatca cctgattgaa cggtataagc ttcgtccgca tgagcagtcg ttcccatgaa
      661 gaatgcagcg ccggcagcca aagttgttcc aaaaagtaaa gttttaagtg atgtcatgaa
      721 aaatctcctt tattcgttaa aaagttttat ttgttgtgtt caacgaggaa tactttaaca
      781 cgtgaaaata tttcataggt aaaagaagca tgacaattta tgacaaatcc acgttttttg
      841 taacagaatg atgttcgctc gatgtgaaaa atgatgagga atttcacata atgcagaaat
      901 aatgggatta gaacaggtgt tctgatgaga aaagaaatgt ataaataact tgaaagaaat
      961 tgcttttgtt catcatttta tttacatatt gcgtatattt tttgtatttt tgcttgagat
     1021 gttacaataa aagaaaaagg aggcggttcc aatgagtaaa agataccaga acatcatggt
     1081 agcagttgac ggatcaagac aatcgatcaa agcgttcgct gaagcccttg acttagcaaa
     1141 ggacaatgaa gcccacttat ttatcgtgtc aatcatcaac aaagttgagc tgacccatag
     1201 tgcctatgcc ttttcaaaaa tctatgcaga tgaaaaacaa agaacagaag tagccatgct
     1261 gaaaaaaatc aatgatgcca aagagtacgg cattgctgag atccacgcaa tagttgaaac
     1321 tggagatcca agaaatttga ttgccaatgt catccctgga caagaaaata ttgatttgat
     1381 cgttatggga gcgacaggaa aaggtgctat acaacaagca ttagttggat cgaccgcttc
     1441 ttatgtcgta tcacatgccc cttgcagtgt gttggtcgtg aagtaatgag ataagggagg
     1501 aatagaaaat ggttcgtcct caagaagtcc gtgcgccaaa agaaaaaata gaaattttag
     1561 caattattga agacggcaca caaacaaaga agggatactc gatcgcttta gtaaagtgga
     1621 aaggaaaaaa aggtgttgct ctgagatggg atggagataa ccaacaagat aaaggattcc
     1681 ctgtcacagc taacggttat catccagcgt ggtttgttct gcctgataaa tttatggaat
     1741 tatacagcta tgattatgca agagccgcag catcaatcaa agcattagat aaattaacag
     1801 aagagcagaa tgaaatggag gaaaaataaa aaagacgaac caatcagcct ttagaaaact
     1861 gattagttcg aggagtaaaa atgaaaaaag gttatttggg atgaaactag aataatgcgt
     1921 ataacttaaa taaaacttaa agcaataaaa tggcaagagg gtgaggcaaa tggaagcagg
     1981 aaaagtatta caggaagtaa aagcactatg tgcagataaa aaatatgaag aagcgaaaag
     2041 cctgatcgaa aagaacaaag aaaatttgga agaaaagtac ccgatcgcac aagaatttat
     2101 agaattaaaa caaggaacga tccttcaccg attcaaacat ttttttggta taacagaata
     2161 gaaaaaacga ttaaagatcg gcagaaattt gctgcatctt taatcgtttt ctttttaaac
     2221 atgcgaggga ttcaattctg attcttatat aaaaaataga tccaaataat aagaaaaatt
     2281 actgaaagcg tcaattcgat gatgtgtgtt attaatacag acgttgtttc ccaatgccta
     2341 aaagaaaaaa tttgataagt aaaatataca gcaggtaaag aggccagtaa aactgaaaac
     2401 ttcttttttg tccattttat gtaatagaaa agaatgctta tcataataaa aaaaggaata
     2461 taaaaaacaa attgaccgat cgcgatcata ctattgcctc cgataaataa agtccatgat
     2521 acaaaataac actttgtgcg aaatggcgca agcagttttg tggatttatc cggtaaaatc
     2581 tgtatcgatt ttgaaattag aggagaaact tgctataatc aaagtgaaag aaggagtggg
     2641 attttcatgg atcatgtagt gttagaaatc gatttgcatt tgatcaataa tattcgggtg
     2701 atttactatg ttgtaagtaa cagtgtcgaa caacgtgtac tgacgaataa aataaatggt
     2761 attttagcaa agaaagacgt tcaccgattc aataatggtg aaggaagtta ttatagtatc
     2821 ccagtagaaa aaattattta tacgacagtc aaagtcagag aagatctaga taccaaaaaa
     2881 gcatatgaac ctatttttac aacttattga ttgacagcag atggaggaaa aaaatgaatc
     2941 catatgaaca acttattcaa gatttgatcg atggaaaaat cgaaaagatt gatgtaaaaa
     3001 gagaagaatt aatggctttt cgagaagcgt ggctgaagtt ggagaatcgt aaatatgtgg
     3061 tgggaaaagc ctcactgaac ggcaatgtga cttatcatta cgatccgaca cgtttatttt
     3121 agtatgaagt attcagaaaa gaaccaaagg aggacgttgc agcagcattg tcctcctttg
     3181 attttacaaa agtgaaagtt ttacttattt gaatagattt ttaaatttgt ttttgacact
     3241 gtcgatattt acatctttta aaagattttg ggctttctct ttataaggtc ctaattgttc
     3301 tttatgttct tcgataaatc gttttgcgcc atcgaaattg ccgttcttaa tcatttcctt
     3361 gactttttga aataattctt cttgattcat tttgaacaca tcctttgcta tcaacatgat
     3421 tttttacatg gacaaaacga gaaaaactga tttatccaca cgtcaataat atcaaataac
     3481 gatcattttt actaaaaaaa cactcgattc tcgcttctaa agtaggagaa aaatctccaa
     3541 cttgggacgg atggaatttc tttaactgac ccatatactg aatatataac aaggaggtag
     3601 aaagatgaaa gtgattaaat atttgattgg actggcggcg attagtggta ttttgctatt
     3661 tggactgaaa tattatactg aaggaagtta tggagaaatc cctggtatac ttgatcagct
     3721 aaatccatta gttgaaaaag gagaggtcta tgtaaagaca caaaaaccag aggaagtaaa
     3781 tgaatatggt acagcaaggt atgtgcagaa agctgctgat gccaatggga aagaacgaac
     3841 ggttgaattt aatggtcttt ctgtgttaaa agaaaatcat tatttgaaaa ttagcaataa
     3901 aggagcacac atagaaacgt atgaggaagt tcctagagaa aaagttccgg agaaagcatt
     3961 agcaattatt gggtaaatca gtttttgtat taagaatacg cccgatttta ttattcataa
     4021 tttaattatg taaactaaat acaagtagta aaaataatac aataatcccc ctgcaaaaag
     4081 attgttcttt tacagggggt tcattttttc agcaagcaca tcaaattggg atggcagggt
     4141 tcgaacctac aattgcttga ttcagagtca agtgccttac cagtttggct acatcccatt
     4201 tattcaacaa aataatcata gcactttcct aaaaaaacgc aagttatttt tcttgatcgg
     4261 atagttgttg ctttactcgt aaaaggcggc gtactagttt cttttctaat ccagcaggaa
     4321 gggcaatcag ttctgctact gacaagacgg tgtccaataa ctgatattct ttgacaggtt
     4381 cattcataat atgatagatg tttgctaaac gttcaatata ttcaaagcga gtatactctg
     4441 ttcgagcaat tagaaatttc aataaatcgg tggctttctc gtactcttga tctgcgtaat
     4501 aaacaagaga ttgacgatac aatttgattt ccagttcatt gagggtagca ggtctgcgac
     4561 gctcgttcca ctcattaata gagactttac cttgaacatt tcccttgcag tcacggacaa
     4621 aaataatcgg aatttcattt ggatccattt ttttatgtgt gaatttttcc attatctacg
     4681 ctcccttcaa aggtttggta tcttgagtat aagggatttt tgtttgaatt actagctttt
     4741 ctccaaagtt agcatctgtc cacccattgc agtgaaaatc gccgaaaaat cgttgatcgg
     4801 tactgctcga ttttttacac catagggatc gttgacataa atattttctt tgtcatatcc
     4861 agtgactaca caagcatgaa caagaggagt gactcttact tctccattat ttgtggtcca
     4921 agtcataaaa tcagtttcat ctgggacttc aaaattgata gtcacagaag tccagacagg
     4981 atttccttta gatagtgctt ttttgatatc atcgagttga gcatcggttt ttggaaaagt
     5041 gtgataatcc gtttggacga tttgctgagc aagggaggca actgggggaa catagacgac
     5101 catagcccag tctccgccac tgatatcacc aacaaatcct tcattaggat cgccatgagt
     5161 cccatctgca ttgaaaacag ggacgtaatc caattgctca gctaactggt ttttagttgt
     5221 ttcataacca taaaaagata aaagcataga aagcgaagtg acttcacagc cattttctaa
     5281 agaaggagaa tcaaactggc tctctaatgg aacatctagt aaaacttctg ctttctcttt
     5341 tgtctttttc gttttttgtg ttgaactttt ttgtgcagtg ttcattgtat gttctggaga
     5401 atggatatgt aggtaataac ttgtaccgct taataaaaga gcagctgtgc cccctagaaa
     5461 caatagtttt ttgaacgttt ttttcttcat ttgaaatctc ccttttcagc tgtttatctt
     5521 tcctattata aa
//
LOCUS       DAMEEU010000117         5310 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.121, whole genome shotgun sequence.
ACCESSION   DAMEEU010000117 DAMEEU010000000
VERSION     DAMEEU010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5310
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.121"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(72..1220)
                     /gene="nagA"
                     /locus_tag="PB779_002700"
     CDS             complement(72..1220)
                     /gene="nagA"
                     /locus_tag="PB779_002700"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HDE0740185.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            complement(1296..2132)
                     /locus_tag="PB779_002701"
     CDS             complement(1296..2132)
                     /locus_tag="PB779_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740186.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            complement(2316..3533)
                     /locus_tag="PB779_002702"
     CDS             complement(2316..3533)
                     /locus_tag="PB779_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HDE0740187.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            complement(3682..3861)
                     /locus_tag="PB779_002703"
     CDS             complement(3682..3861)
                     /locus_tag="PB779_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740188.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            3916..3999
                     /locus_tag="PB779_002704"
     tRNA            3916..3999
                     /locus_tag="PB779_002704"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3950..3952,aa:Leu,seq:gag)
     gene            complement(4239..4817)
                     /locus_tag="PB779_002705"
     CDS             complement(4239..4817)
                     /locus_tag="PB779_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740189.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
     gene            complement(4823..5206)
                     /locus_tag="PB779_002706"
                     /pseudo
     CDS             complement(4823..5206)
                     /locus_tag="PB779_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         1653 a         1082 c          838 g         1737 t
ORIGIN      
        1 tttactagaa cacaaaaaaa accttaaaac caaacttaag aagtttagtt ttaaggttaa
       61 cttaaattat attatgcgtg gaaacgttcc acgccatcta gataagttgc ttccaatgtc
      121 atatcagggt tcaatacgat aaagtctgca tcgcgtcctt gagcgatttt tccacatgta
      181 tcatcgattt tacagctgat tgctggaatc agactagcca tcatgactgc ttgttctggt
      241 gttgctaatc cccagtctac aacattttta attgcttctt tcaatttcaa tatacttcca
      301 gctaagttgc cagattctag acgtgctgtt ccttctttta ctactactgg aaattcgcct
      361 aaattgtaat ttccatcagg catcccaccg gccatcatac agtctgtaat taatgcgaca
      421 tgatcatgtc ctgctttttc cattaggatt cccgcagcat ttggatgtac atgatggcca
      481 tcacaaatca attcagaaaa gacatgttct aaagataata acgcacccac catacctggt
      541 tcgcgatgat tcaatccacg cataccattg aaagcatgga caaatacact tgcgcctgct
      601 tcaacagctt tttgcgcttc ttctagtgta gcattactgt gtcctagaga aacaactact
      661 ccttcttcag tcacttgttt gacaaactct tctacacctt gacgttccgg tgctaaagca
      721 atttttttga ttaaaccacc tgaagcttct tgccattcat ggaaagtatc caaatcagga
      781 tccccgaaat aacttgggtt ttgtgcccct ttgtgttctt ctgtgaagaa aggaccttca
      841 aaatagattc ctttgatttt agctcctggt gcttcctgat acattttgcc gattgtctca
      901 gctacatctt ttaaacgttc tttgcttgac gtcaatgttg ttggtaaaaa tgaagtcact
      961 ccacaagata acagaccttc agacatcact ttgatgcctt ctgcatcatt atccattaca
     1021 tcatgattca tatagccgtg aatatgtgta tctaccaaac caggagcaat ccatttgccg
     1081 ctttggtcaa tgatgttgac ttctccctca ggtagttctt tggtgtattc accaaaaagt
     1141 ccatcggtaa tttcaagata gcctgcatgt ttgacacctg acgctaaaaa gaatttgtca
     1201 gcatagataa aagttctcat tctattctct ccctttgttt ttctacctct aaagtactct
     1261 tatttagaga agaagtcaag aatggtctac accatttaca aattttttga aatttgtttc
     1321 acagcttgtg ctaagccttc atagaatgct gctctttctg gttcttcttt acgcttgtat
     1381 attaagcttt taagcacaaa taaatcattg aggtaatagt agctattctt ctcttgagcc
     1441 caatagattc cttgattcac ctgttctaac gcttcgtcga tttcattttg atggaataag
     1501 aaatttccat aattataaaa aatttgcgaa aattcacttt ttgatcgttc atcagctgat
     1561 tgatgcagca gttggatgct tcgactcaaa tagtagcgtg cttcagccgt ttttcctgcc
     1621 acaccatata tttttccgat acaactaatc agttgtattt ctgtgtcaga aacatggatt
     1681 ctttcttttt ggctagagta gcttaatgct tctttcaaat aataaaggga ctgagagata
     1741 ttttgacgca acgtgaattc gcaaacaccg agataataat aatagcgttg aaagtcagtt
     1801 gcttgataca gattttcaga aatatcagaa gattttagta cttgttctaa cttccgataa
     1861 tcacgttttt ggaaacaact atccaacagt tcaaataatt tatcgtttgt ccgagtagtt
     1921 tttcgagaga gattcatcac atgatcaatc gttaccccta gccgttgaca aatctgcatc
     1981 atcaccaata cattcggcag ttcctcatta ttttcgatcc gacttaatac actttgtgaa
     2041 caaatatcat gcgaaagcat tttttgcgtc attttttgtt cttttcgaat ctctttaatg
     2101 atcgttccaa aggactcgat taacgtttcc ataagtatcc tccccaaaat atgcgtattc
     2161 gcattctatt cgtattttac tttaggaagt cgcaaacttc aagaaaagac ttgcaactaa
     2221 ataatatact ttagttattt aagaaaactc cactagaaag agagcctcag tgtgtttgtc
     2281 tgtggccctc ctactgaaaa atttggtttt taaaatcatt tttggcgata ggttgctagg
     2341 aattctctca ttttcttagc tgtttgtttc aaatcatcca ttttaggaag ataaacgatt
     2401 cgaaaatgat ctggctggtt ccaattaaat ccaccaccat gtacaagtag aatatgatgt
     2461 tcatgtaaaa agtccaaaac gaatttttca tcatccaaaa tattgaatcg ctttgtatca
     2521 atttttggga atatataaaa agcagctttt ggttttacgg ctgaaagacc aggaatatca
     2581 ttgattgcat tatagatata ttctctttgt tcatagatcc ttccgcctgg caggagcagc
     2641 tcatcgacac tttgataacc gcctagcgcg gtttggataa tttgctgaga caatacattg
     2701 gaacacaaac gcatggagga caacatattc agcccttcta tatagccttt gacgtgtgac
     2761 ttatctccac ttaggaccat ccagcctact cgaaatcctg ctacacgatg agatttggat
     2821 agaccgttca gcgtaacaac gaacaaatca ggcgctaatg tagcaatcgg aatatgttct
     2881 agaccatcca tcactaagcg atcatagatt tcgtcggaat aaataatcag gttattttgt
     2941 cgagctactt caacgatttc ttctaataat tcttttggat aaagtgcccc agtaggatta
     3001 ttaggattaa tgataacaat agcttttgtc cgactcgtta tttttgattt gatatcatca
     3061 atatcaggat accattctgc ctcttcatcg caaatataat gaacaggtgt gcctccagct
     3121 aatgcaatag aagccgtcca caacggatag tccggcattg gaaccagtac ttcatctcca
     3181 ttgtccagca acccctgcat acacatcgtg atcaattcgc tcactccgtt gccggtgtag
     3241 atatcattga tcgtcacatt cggaaaatgt ttcagttggc aatattgctc aattgctttt
     3301 ctagcagaaa agatcccctt ggaatctgag tagccttctg agtcacgggc attcatgatc
     3361 aaatcacgaa tgacttcgtt tggtgcttca aatccaaaag gtgcgggatt tcccgtgttc
     3421 aattttaaaa tactaatgcc ctcttcttgc atccgctccg cttcttctag aacgggaccg
     3481 cgaacatcgt aactgacacc ttctaatttg ttggattttt caaattctct catcacttag
     3541 ccaatccctc atttcaaaaa gttagaactt tccaaatttt ttgttattta ctatttcaat
     3601 atcatactcc atcctagaaa attttgccac ttatttagga aaaacgtaag tattaaaaaa
     3661 acacaaacaa gcgttgagaa cttaattgtc atgatagtca ttccatagat tcgctgccca
     3721 atccattgca attccacaaa tgattcctag cataaaacca agcaaaaaac gtccgaatgc
     3781 aagtccaatc aatacaccta agatcattcc cagtcctgaa aattctccgt catatttctc
     3841 catcttaata agtcctccca tttttgagct tgacaactat gtaaaacctc gctatcatta
     3901 gtgtgttatt attacgcaga tgtgttggaa ttggcagaca agcatgattg agggtcatgt
     3961 gagcgttagc tcgtgtgggt tcgagtccca tcatctgcac tacaactcgt gaagttaatt
     4021 ttgcttcacg agtttttttg tttgaacgtt tctttatgcc attatataca tatcactgta
     4081 tcctttacaa aaagaacgta caatcatgta aacagcctga ggtgagtata tgaaggtcgg
     4141 aaacaagcta ctcgtagaaa cttgcaagtg ttaaaacaat taatcgaaaa acgagtaaaa
     4201 tccctcacct aatactaaag cgagggattt tttgtatatt atctgtttat caccgttatt
     4261 ataaaggtac aaataccaag cacggttaat ccaaattgca taaattcatt tttttgtaca
     4321 ctcatgcttt tcattagctc tttaactgcc attagtacta agatggcgat aacaacataa
     4381 agtatatagt acgtccgcat tccggaagcc catactgtgg gagaaaatcc cataattaac
     4441 cttgaacaaa atcccattat catcaaaata actaaaaaaa tagaagtttt cttattgtca
     4501 aaacttaaat aaattccaac aattaaacat agtaataatg ccaagactac taaagtagct
     4561 atccaagtac ctggataaaa aagtgacagt ttcgttccta actctgtaaa gagattattc
     4621 aggttactac tactccaaat cattgccctt ttatttccat tgacgtaagt aaagctttga
     4681 cccattgtat taccaaaata aataatcagg tttaagaaaa acggtaatgc agtcaatata
     4741 cgcacataat agttttgaca tttcctatat gttagaagga aaattaagaa aaatagcaat
     4801 aaaaataaga tattcatgtc taaaaaaacg gctttccaaa tgatgaaata cctaaatcta
     4861 acttattaag aaagttgaaa tttttatatt caggaaacca tttattaatt tcatgtgcag
     4921 cacgtaatgc attccctgga gttgtcaaag agaaaattaa ttctgctaag cttattattg
     4981 aaaatactga taacttataa ttatatcgtc cattgacaat caaatataaa ctaactatac
     5041 ttgttagaac aaaaaaacag gcgttgactt gttcttgatt agttaaaaat atcaataaag
     5101 gaatacttac ccaatatatt tttctattta tttcttctcc tcttaagagt tgaaaaaacg
     5161 gataaaaagt tagtaaacta aatgctactg gccactgata gttcaaggtg gttgctctcc
     5221 aaccggtttc ccccattact gtcaatggta ttaaacagta tatagagcaa accaataata
     5281 aatttttaac atttattttc tcaaaaacat
//
LOCUS       DAMEEU010000118         5208 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.122, whole genome shotgun sequence.
ACCESSION   DAMEEU010000118 DAMEEU010000000
VERSION     DAMEEU010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5208)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5208)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5208
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.122"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            277..1368
                     /locus_tag="PB779_002707"
     CDS             277..1368
                     /locus_tag="PB779_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740190.1"
                     /translation="MIIVRLFLSKQIKNDIKFVVVNLVKAVFLTCALTSYFWYPMLQQ
                     MNYQEIHSPFKTDLQLEALSISDSIIQALNNDITTYTMGLLGLVALIFPLFILKEMEK
                     KEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQFPWRILGIQIFFSSMIITLVFMKK
                     TMNKKYSWLIIGATVVFLVVTSIAAKENYAKVIQSKHGHIVINEETLPRYTTSDMGGL
                     YDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAADNNITYTVASNKKQKVTVPVYAYL
                     GTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEITTKYTPTALMALWISILTYCLVVY
                     SSFKRFAPNKLKDSRYVTKKEINKKNENK"
     gene            1355..2989
                     /locus_tag="PB779_002708"
     CDS             1355..2989
                     /locus_tag="PB779_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740191.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIFIRLVSKGFKNADFI
                     AIFKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNN
                     DLTTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAK
                     LLQFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFN
                     QKIISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNL
                     PYKTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGV
                     ADIKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            3164..3997
                     /gene="msrA"
                     /locus_tag="PB779_002709"
     CDS             3164..3997
                     /gene="msrA"
                     /locus_tag="PB779_002709"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HDE0740192.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            4110..5066
                     /locus_tag="PB779_002710"
     CDS             4110..5066
                     /locus_tag="PB779_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HDE0740193.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
BASE COUNT         1826 a          805 c          952 g         1625 t
ORIGIN      
        1 agtttttatt atggagaaaa gttttttaaa aagatagatg ctgctttttt atttagttgt
       61 ttatatactt ttgcaactta tcgaacagtt gatatctatt atcgatccgc aattgcagaa
      121 gcaatcgctc ttacgattat cccagctgtt ttatattatg cttatggatt gatattcaat
      181 agagaaaaaa aagtcatcgc tttatctgtc agtataagtc tacttgtgta tactcatgtc
      241 ttaactacac tattgtgtag tgcattgatt gcttgtatga ttatagttcg tttgttttta
      301 agcaagcaaa taaaaaacga tataaaattt gtggtcgtga atttagtaaa ggctgttttt
      361 ttgacttgtg cattaactag ctatttttgg tatcctatgt tgcagcagat gaattatcaa
      421 gaaatacaca gtcccttcaa aacagatttg cagctagaag cactttctat ttcagatagt
      481 atcattcaag cgttaaataa cgatattaca acatacacta tggggttatt aggattggtt
      541 gcgttgattt ttcctttatt catactgaaa gaaatggaga aaaaagaaaa aatcatctat
      601 gttggcgtag tttctacatg ggtatgcgta actaatttat ttccatggtt tttgtttcaa
      661 aaaacaccga taagcttgct ccagtttcct tggcgtatct taggtatcca aatctttttt
      721 tcttcaatga tcataacgct tgtttttatg aaaaagacta tgaataaaaa atattcatgg
      781 ttaatcattg gcgctactgt ggtgtttcta gtcgtcacgt ctatagcagc aaaagaaaat
      841 tacgcaaaag ttatccaatc aaaacacggt catattgtta tcaatgaaga aacactccca
      901 cgttatacaa catcagatat gggaggatta tacgattacg ccccaacaga agcgataaaa
      961 gaaaggcctc acttagaaaa acatgaagta aaagtaggag aatcgtggga aaaagggaag
     1021 tataaagctg cagataataa cattacttac acagtggcaa gcaacaaaaa gcaaaaagtg
     1081 acagtaccag tatatgctta tttaggtaca caggtaaaag taaacggtaa agtcgtaaat
     1141 gactcttata aaaaacatgg cttagtgaat gtggatgtaa atgctggaga aaataagata
     1201 gaaattacaa caaaatatac tccaactgct ctcatggctt tatggatcag tattctgact
     1261 tattgtttag tggtgtattc aagttttaaa cgatttgcac ctaataagtt gaaagattct
     1321 cgatatgtga ctaaaaagga gataaacaag aagaatgaaa ataaataaaa aagtagtaat
     1381 attgagtgga ttaattatag ttagtagtat atattctttc atctttttca aaaatacaca
     1441 gagtatttat accactggag atctttcttt tcacttatct cgaatcaagg ggttatcgac
     1501 tatttttacc agtccgatta attatgagac attcaattat actggatatg gtgtaaatta
     1561 tttttatccc tttctgactt tttttccagc tgtaatgtta tattggatga caaaaaattt
     1621 gattgtaagc tatattattt acgtttggtt attgaacttg tgtacaacac tcgtagctta
     1681 tcattatggc gagcggtttt taaaacaaaa aaaagcggca tttttattta gttgtctcta
     1741 tattttctct gcttatcgga cagtagacat ctactatcgt tccgcaattg ccgaagctat
     1801 cgcaataaca cttgttatcc ctgtattatt ttatgcttat caaatcatct ctggaaaaga
     1861 agaaaagtat ccgtctgtaa agctagcatt gagtatgagt ttgctagtgt acagccatgt
     1921 actatcaaca ttaatgagta cagcattaat tatcattttt atttttattc gtttggtttc
     1981 taaaggtttc aagaatgcag attttattgc tatatttaaa aaattattta gtgcggcagg
     2041 aatgacattg gttctgacga gtgctttttg gtatccgatg tttgaacaaa tgctctacca
     2101 aaaaatcaac aaacctagcg tgacaaattt atatgctcat gcatctaatg tgttcgatag
     2161 tctgactgaa gctatgaaca acgacttaac tacttactca atgggactag ttggtctgtt
     2221 atctttatgt attcccctga ttttatttaa aaaattaaca aacatagaaa aaaagattta
     2281 ttatggtacg tgtttgactt ggctagctac aactagtttg gtgccatggt atcttctgca
     2341 aaatacgcca gccaaattgt tacaatttcc ttggcggatc ttaagcttgc aaataatatt
     2401 ctcttctctg atattaacga tgatattttt caaaaataga agatacaata agacaagaga
     2461 actattttat ttatttatga ctgttttgtt attaatcact ttaactgttt ctagtaaaaa
     2521 aaatttcaat caaaaaataa tttctcagcc gggacatatt gttgtaaaca aagaaacagt
     2581 agaggcgtat accactaaag gaatggatta ttttttatat gattattctc ctatcgcttc
     2641 attggagaat aaggagcata taataaaaca cgaagcaaag attggcagtc aatgggtaaa
     2701 ccttccttat aaaacaactg gtagttctat catatataga gtaactaatg agaagagcca
     2761 agtaatcaca cttcctgtat atgcttattt aggaacgaat gtagaaataa atcatcaacc
     2821 tgtaaaggag caggtgaatg ctaatggatt ggtacaaata agcggagtca aaggagttgc
     2881 tgatattaaa gtaagcacaa gttatacagt aacgactatt atttcttatc ttgttacatt
     2941 aactgcatat ttatgtttat tttttaaaat agttttccat aaaaggtaaa ttaacttttc
     3001 atttataaaa taaattgatt aaaaaggaga atctgtcgat aaggattctc tcttttttat
     3061 acgaaaaatc tgtaggggga tgaagtaatc gcttatttcc tcactttatg ataaattaca
     3121 gctaaagtca ctagcttgtc ttcttcggaa aggaggagaa tctatggatg aggaacaaat
     3181 attcattcaa acactttata atctgatttt gaatccgaat acacgagatt gggaacgaaa
     3241 agtattgatt cagacaaaga atgacataag agaaaatata tccgttaaag aacagttatc
     3301 aaaactagaa gcaacactac gtccattagc tatccgaatg aatctgacgc ctgatgtaat
     3361 ggacttttat ttattgatta cggaaggatt tgataaggag caaaaatatg acttttccaa
     3421 gcatgccatg caagatgctg actatcaaga acgtgcagta tttgcagggg gatgtttctg
     3481 gtgtatggtc gagccgtttg aatcgaaaaa agggatccta tctgttttgt caggatacac
     3541 gggcggacat gttgaaaaac caaattatga tcaagtaagt ggtggttaca caggtcatgt
     3601 ggaagctgtg gagatcattt atgacacaag agaaataagt tatagcgagt tgctgacaat
     3661 ctattggcaa attactgatc ccacagatac atttggacaa tttcaagata gagggaagca
     3721 atatcgtcca gtgatttttt atcaaggcga acgacaaaaa gaattagcgg aacaatcaaa
     3781 acagaaacta gacagttcag gaactttcca ccaaccaatc gtcacaaaaa tcgaaccagc
     3841 cggtacgttt tggccagcag aaaactatca tcagcaattt tacaaaaaac aaccgaaacg
     3901 ttataaaaaa atccagcaag cacgtaatca atttctgatc tatcaacgag taaaaaacaa
     3961 atggcaaaaa aatatacgaa aaaatcattt tgattaactc cttttcttta aaatgtagta
     4021 aactaaaaat agaaaaaaga aagcgtttta aaaagatttg atgaggagga gaaaaattgt
     4081 atattgcaga tagtgcacgt tatgaaaaaa tggaatatcg taaatccggt cattcaggtt
     4141 tgaaattacc gattttatct ctcggattat ggcaaaattt tggtgattat gatcctatcc
     4201 ataatcaaag agagatttta agaggcgcat tcgacatggg aattacccat ttcgaccttg
     4261 cgaataatta tggaggccct gctggagctg cagagaaaaa ctttgggcgt atttttagag
     4321 aagattttca agcctaccgt gatgaactga ttatttctag caaagcaggt tatcatatgt
     4381 gggaagggcc atatggggaa tggggctctc gtaaatccat catttcaagt tgtgaccaaa
     4441 gtctccaaag aatggggcta gattatgttg acatcttcta tcatcatcgc ccagaccctg
     4501 atacaccttt ggaagaaaca gcagaagctt tgatgcaact tgtaagacaa ggaaaagcat
     4561 tatatattgg tatatccaac tataatggag aagatacaaa aaaaatgact gaaattttaa
     4621 aaagaaagga agcaccgttc attattcatc agatgcgcta caatatgttt tctcgtgcac
     4681 tactagaaga cgatctatct ccagtattag aagaagaagg gctaggggca atcacgttca
     4741 gtccgcttgc tcaagggttg ctgacaaatc gttatctaca tggtattcct gaagattcta
     4801 gagcacatcg taaggaaata ccattccttt cagaagaaca agttggatca actctggaaa
     4861 aaatcaaagc actgcaaaca atcgccgtat cacgaggaca atcattagcg caaatggccc
     4921 ttgcatggaa tttgcgacaa aaatctgtta caagtgtact ggtcggagca agtcggttaa
     4981 gtcagttaca agaaagtgtt cgaatgatgg ataatttaga tttctcacca gaagaagaat
     5041 tgagaatcga ccaaattcta gaatagaaac gatgtaatca aactttttat ccatatatta
     5101 aaaaaaacaa aagatgacat caagaatcga atgaagatcg tctgttattg aacatcatat
     5161 tttttgtcgt tcaaaataaa aatgatcgaa ggctaggagt gaatttta
//
LOCUS       DAMEEU010000119         5087 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.123, whole genome shotgun sequence.
ACCESSION   DAMEEU010000119 DAMEEU010000000
VERSION     DAMEEU010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 5087)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5087)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5087
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.123"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(47..871)
                     /gene="iolB"
                     /locus_tag="PB779_002711"
     CDS             complement(47..871)
                     /gene="iolB"
                     /locus_tag="PB779_002711"
                     /EC_number="5.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-deoxy-glucuronate isomerase"
                     /protein_id="HDE0740194.1"
                     /translation="MEKTLKHQPLNKELAPGVKQIQNIRQSNSALSYIEFQILELEKG
                     ASYKETGSQQEVCIVILTGKIKVKAADTWYEDLGTRESVFEKIPTDSIYLPAEHSFEL
                     VATTDNVRLALCYSPAKKALPISVIRAEDNTVEERGLYQNKRLVHNILPDNVDTASSL
                     LVVEVYTEGGNFSSYPPHKHDQENLPHESFLEETYYHELDPEQGFVFQRVYTEDRSLD
                     ETMTVEHQNVVEVPKGYHPVGVPDGYTSYYLNVMAGPERIWKFHNEKKHEWILQRK"
     gene            complement(910..2826)
                     /gene="iolD"
                     /locus_tag="PB779_002712"
     CDS             complement(910..2826)
                     /gene="iolD"
                     /locus_tag="PB779_002712"
                     /EC_number="3.7.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002397168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /protein_id="HDE0740195.1"
                     /translation="MEKTVCLTTAQALLKFLNQQYISIDGKETPYVEGIFHVYGHGNV
                     LGIGQALELEPGHLKSYSGKNEQGMAHAATAFARQNLRKKIFAVSTSVGPGAANLLTA
                     AGTAFANNIPVLFLPADTFATRQPDPVLQQLEHASSVAFSTNDAFQAVSRYWDRINRP
                     EQLMSALLRAFEVMTNPATMGPATICLPQDVEAEAYAYPEEFFKKRVHYIDRRIPTAR
                     ELAEASQRIKASKRPVIIVGGGCKYSEAGEILEQISRDCQIPLVETHAGKSTVSWDFK
                     NNLGGMGILGTSAANKAVQQADLIIGIGTRYTDFTSASKSIFNFEQAKMMNINVSRQQ
                     AAKLEAFQVVGDAKATLEQLAPMIEGYQTAYGEKIDELKEEWISERNRLKAAHFKRKD
                     FTPEIKDHFSQEILNEYADALATNLTQTEVFIHLNDFVDEDAIVIGSAGSLPGDMQRL
                     WNPVKENTYHLEYGYSCMGYEIAGAMGVRMARPEQEVYALVGDGSFLMLHSELVSSLQ
                     YDKKINIVLFDNSGFGCINNLQMDNGGASQGTEFRNTKDEIMNIDYAKVAEGYGAKTY
                     RVSSIAELQAAVEDAKKQTRSTLIEIKVLPKTMTEGYDGSWWNVGISEVSGKAAMQEA
                     YKAKQAKLATIRKY"
     gene            complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="PB779_002713"
     CDS             complement(2837..3871)
                     /gene="iolC"
                     /locus_tag="PB779_002713"
                     /EC_number="2.7.1.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-2-deoxygluconokinase"
                     /protein_id="HDE0740196.1"
                     /translation="MSYIKFDQSKEFDLLLLGRVAIDFNPAYNDQVKEEFKPLKKVHM
                     FEKFVGGSPANIAVGVTKHGMKAGFIGTVSDDQFGEYVIDYFNEQGIDTSQISKAQHG
                     EKLGLTFTEMLSSKESNILMYRNQAADLQLSVEDIDEDYLKRSKALLISGTALAESPS
                     REAVIKAVMLAKRNNVKIIFDIDYRAYNWKNNDDISIYYSMIAKESDIIMGSREEFDL
                     TEKLIQPNMSDNESAAFWHSCGAEIVVIKHGMKGSTAYTADQQQFSIKPFPVEARKGF
                     GGGDGYGSGFLYGLFEGWEIIDCLEFGSAEASMMVKSNNCSDSLPTTQEVKDFITLEK
                     EIYGEMIARI"
     gene            complement(4028..5044)
                     /locus_tag="PB779_002714"
     CDS             complement(4028..5044)
                     /locus_tag="PB779_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016633586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0740197.1"
                     /translation="MAGTIKEIAEKAGVSRGTVDRALNDRGRINPEVAERIRAIAKEM
                     NYVPKKKKVIKETTLKLGIVTQLAKSSFMIPIRSGLESIIGDLKKRNIDCFLEEVDGV
                     DEAAQLQALDRLVELGVKGIAIMPVDSDGIREKINQLTDQGILIITFNSDILGTNRQC
                     FVGMDNFKSGKTAAGLLGMLTKGKGKVLAITGYFGNSVNSLRVAGFVEELKESFPELE
                     LTGVQSSFDSSAEVEKILSNTLENYSNLDGVVVFSGGQAGIARALEKIDESKRPFVII
                     YDLTKNNIEMLKNDQVDFLIDQDGFVQGYRSLLMLANQLQNNKTVTKDALFTDIIIKT
                     KYNI"
BASE COUNT         1337 a         1270 c          909 g         1571 t
ORIGIN      
        1 acctaactaa acctaactaa actttatgta tctaacagct taataactac ttgcgctgca
       61 agatccattc gtgtttcttt tcattgtgga atttccaaat tcgctcaggt cccgccatca
      121 catttaaata gtaggaagta tacccgtcag gtaccccaac tggatgatag cccttaggaa
      181 cttcgacgac attttgatgc tctaccgtca tcgtttcatc tagtgaacga tcttccgtgt
      241 agacccgctg gaaaacaaat ccctgctctg gatcaagctc atggtaataa gtttcctcta
      301 aaaaagactc atgtggcaga ttctcttgat cgtgcttatg aggaggatag ctggaaaaat
      361 taccgccctc ggtataaact tcgacgacca gcaggctgct ggcagtatcg acattatccg
      421 gtaaaatgtt gtgaacaagt cgtttattct gatagagtcc acgttcttcg acggtattat
      481 cctccgcgcg aatcacactt atcggcaaag cttttttcgc tggtgaatag caaagcgcca
      541 atcggacatt gtctgtagtt gccacaagtt caaacgaatg ctccgccgga agataaatac
      601 tgtcggttgg aattttttca aaaacagatt ctcgtgttcc taaatcttca taccaagtgt
      661 ctgctgcttt aaccttaatt tttccagtca aaatgacgat acagacctcc tgttgactgc
      721 cggtttcctt gtaagaagct cccttttcca gctccaaaat ctgaaattcg atataactca
      781 aagcagaatt agactgccga atattttgga tttgttttac tccaggtgcc agttctttgt
      841 ttaatggttg atgcttcaat gtcttttcca atcaatccac tccttatttt caatcacaaa
      901 aagcaatatt taatactttc tgatagtggc aagtttcgct tgtttggctt tgtaagcctc
      961 ctgcatggct gctttacccg atacctctga gataccgacg ttccaccagc tgccgtcgta
     1021 gccttctgtc atggttttag gaagtacctt tatctcaatc aacgtcgatc gcgtttgctt
     1081 cttcgcatcc tcgaccgctg cttgtaattc tgcaatcgag cttacacgat acgtttttgc
     1141 accatagcct tcagcaactt tggcgtaatc gatgttcatg atctcgtcct tggtatttct
     1201 gaattcggtt ccttggctag ctccgccatt atccatctgt aaattattga tacagccgaa
     1261 accagaatta tcgaaaagta caatgttgat ttttttatca tattgcaaac tagaaaccag
     1321 ctcgctatgc aacatcaaga aactgccatc gcctactaag gcatagacct cttgttctgg
     1381 tcgagccatt cttacgccca tcgcaccagc gatttcatag cccatacaag aataaccgta
     1441 ttccaaatga taggtattct ccttcacagg gttccataag cgctgcatat cccccggcaa
     1501 tgaaccggct gaaccgatca cgatcgcatc ctcatcaaca aaatcattta aatgaatgaa
     1561 gacctctgtt tgcgtcaaat tcgtagccaa cgcatcagca tattcattca agatttcttg
     1621 agaaaaatga tctttgattt ctggcgtaaa atctttacgc ttaaaatgcg cggcttttaa
     1681 ccgatttcgc tcactgatcc attcttcctt cagttcatcg atcttctcgc cataggcggt
     1741 ttggtaacct tcgatcattg gggcaagctg ctccaaggtc gctttcgcat caccaaccac
     1801 ttgaaaggct tccagcttag cggcctgttg tctgcttacg ttaatattca tcattttcgc
     1861 ttgttcaaaa ttaaaaatac ttttagaagc tgaggtaaaa tcagtgtagc gtgtgccgat
     1921 ccctatgatc agatccgctt gctgcacagc tttattagca gccgaagttc ccaaaatccc
     1981 cattccgccg agattgtttt taaaatccca cgaaacagtc gatttacctg cgtgcgtttc
     2041 aactagcgga atctgacaat ctcttgagat ttgctcaaga atctcaccag cctccgaata
     2101 tttgcagccg cctcctacga tgatgacagg tcgtttactg gcctttattc gttgactcgc
     2161 ttcagcaagc tcacgagcgg tcggaatcct gcgatcaata taatgtactc tttttttgaa
     2221 aaattcctcc ggataggcat aggcttctgc ctccacgtcc tgcggcaaac aaatcgttgc
     2281 cggacccatc gttgccgggt tcgtcatgac ttcaaaggcc cgcaataacg cggacatcaa
     2341 ctgctctggt cgattgatgc ggtcccagta gcgagaaacc gcttgaaatg catcatttgt
     2401 cgaaaaggct acactgcttg catgttccag ctgctgcaag accggatcag gctgacgtgt
     2461 agcaaacgta tccgccggta aaaaaagtac ggggatatta tttgcgaatg ccgtacccgc
     2521 tgctgttaac agattggccg cgcccggtcc aacagatgtt gatacggcaa aaattttctt
     2581 gcgtaaattc tgtctggcaa aggcagtagc cgcatgggcc attccctgct cattttttcc
     2641 gctataactt ttcaaatgtc cgggctctaa ttccagcgcc tgaccgatcc ccaaaacatt
     2701 tccgtgacca tagacatgaa agataccttc aacataaggc gtttctttgc cgtcgatgct
     2761 gatgtattgt tgattcaaaa attttagtaa tgcttgtgct gttgttaaac aaaccgtctt
     2821 ttccattttt ttcaccttaa atccgagcga tcatttcgcc gtatatttct ttctccaatg
     2881 taataaaatc ttttacctcc tgagtcgtcg gtaaagaatc tgaacagtta ttgcttttga
     2941 ccatcattga tgcttccgct gagccaaact ctaaacaatc gatgatctcc cagccttcga
     3001 ataaaccgta taagaaaccc gagccgtaac catctccgcc gccaaagcct ttgcgtgctt
     3061 ccaccggaaa cggcttgatt gaaaactgct gctgatcggc cgtataagca gtcgatcctt
     3121 tcattccatg tttgattacg acaatctcag caccacaact gtgccaaaaa gcagcgcttt
     3181 cattatctga catgttaggc tggatcaact tctcagttag atcgaactct tctcttgaac
     3241 ccatgataat gtctgattcc ttagcaatca tcgaatagta aattgaaata tcatcgttgt
     3301 tcttccagtt ataagcacgg taatcaatat caaaaataat tttgacatta ttccttttcg
     3361 ccagcatcac tgccttgatt acggcttctc tggacgggct ctctgctagt gcagttcctg
     3421 agattaatag tgcttttgac cgtttcaagt agtcctcatc aatatcctca acgctaagct
     3481 gcaggtctgc ggcttgattt cgatacatca aaatattact ttcctttgat gagagcattt
     3541 cggtaaaagt cagccccagc ttttcaccat gctgcgcttt gctgatctga gacgtatcga
     3601 tgccttgttc attgaaataa tcgatcacat attcgccaaa ctgatcgtcc gagactgttc
     3661 cgataaaacc agctttcatg ccatgtttag taacacccac agcaatattg gcaggagatc
     3721 cgcccacaaa tttttcaaac atatggacct ttttcaatgg tttaaactct tctttgactt
     3781 gatcattgta ggcaggatta aaatcaatag cgactcttcc taaaagcagc aagtcaaatt
     3841 cttttgattg gtcaaacttt atataactca atatatccac ctctttatcc gttcttctat
     3901 ttctgaggca agtatagcac gccaaaacaa agcgtgcaat atttatttta gaacgcaata
     3961 ttgcgtgctg tttgaaaatg acggcaaaaa aaacgtgaat cgccttacat cacgattcac
     4021 gcctagatta aatattgtat tttgtcttaa taattatatc agtaaatagc gcatcttttg
     4081 taaccgtttt attattttgc agctgattcg ctaacatcag taatgaacga tagccttgaa
     4141 caaatccatc ttgatcgatt agaaaatcaa cctgatcgtt tttcagcatc tcgatattgt
     4201 tcttagtcaa atcataaatg attacaaagg gccgcttgct ttcatcgatt ttttccaacg
     4261 ctcgggcaat tcccgcttgt ccgccagaaa agacgactac gccatctaag tttgaataat
     4321 tctccaaggt gttgcttaaa atcttttcaa cctcagcact cgaatcaaag ctgctctgaa
     4381 cacccgtcag ctccagttca ggaaacgact ctttcaattc ttcaacaaag cctgccaccc
     4441 gtaagctgtt gacgctattt ccaaagtagc cggtaatcgc tagaaccttg ccctttcctt
     4501 ttgtcagcat acctaacaat cccgcagccg tttttccgct tttgaagttg tccatcccaa
     4561 caaaacactg tcgattcgta ccaagaatat ccgaattaaa ggtaatgatg aggatgcctt
     4621 gatcggtcaa ttgattaatt ttttctctga taccatcact atctactggc atgatcgcga
     4681 tcccttttac tccaagctcc accaatcgat ccaacgcctg cagctgggcc gcttcatcga
     4741 ccccgtctac ctcttctaaa aaacaatcaa tgtttcgctt ttttaaatcc ccgataatag
     4801 attccagacc tgatcggatc ggaatcataa aagaagattt cgccaattga gtgacaatcc
     4861 ccagcttgag cgttgtctct tttatgacct tctttttctt tggaacatag ttcatttcct
     4921 tggcgattgc tctgattctt tctgcaacct caggattgat ccttcctcga tcgttcaatg
     4981 cccgatccac tgtccccctt gacactcctg ctttctcagc tatttcttta attgtacccg
     5041 ccatcttgcc tctccttttt tcctattgtg tttattttat cacaaaa
//
LOCUS       DAMEEU010000120         4899 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.125, whole genome shotgun sequence.
ACCESSION   DAMEEU010000120 DAMEEU010000000
VERSION     DAMEEU010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4899
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.125"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            232..492
                     /locus_tag="PB779_002715"
     CDS             232..492
                     /locus_tag="PB779_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740198.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDHFTRSMGI"
     gene            937..1143
                     /locus_tag="PB779_002716"
     CDS             937..1143
                     /locus_tag="PB779_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HDE0740199.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGQRAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            1191..1394
                     /locus_tag="PB779_002717"
     CDS             1191..1394
                     /locus_tag="PB779_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740200.1"
                     /translation="MVDKEVISEKVAEALLIPRYWTIETPLVEDAPTMLFEDLVKIAG
                     YELHYQENMETYENEYWLTKLEN"
     gene            1410..1847
                     /locus_tag="PB779_002718"
     CDS             1410..1847
                     /locus_tag="PB779_002718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740201.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYHETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYGKFVETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            1840..2547
                     /locus_tag="PB779_002719"
     CDS             1840..2547
                     /locus_tag="PB779_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740202.1"
                     /translation="MNKVIYQLTTEDVSHFLTNKEHLNEVIRRIQKDFSCMEEMKYFI
                     QRVEEQLYLESETSQTKVTVSNNYLDVYKHRPETVKKGTELLRLETEKYIMNVYLERS
                     ELVENFVSCTICRKHYYSESEYYSIFESMELMEEEMEELNSKNATIDDYYLVFTRFLT
                     CGTESIVLMGMDYELAVPEAFLREYVEEVDNPGDDWYTTLTDFLDTYTYDDTEEIQNE
                     LDRKRMPYQRFERKKRQ"
     gene            2927..3106
                     /locus_tag="PB779_002720"
     CDS             2927..3106
                     /locus_tag="PB779_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740203.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDIPALKK"
     gene            3431..3694
                     /locus_tag="PB779_002721"
     CDS             3431..3694
                     /locus_tag="PB779_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HDE0740204.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            3688..4038
                     /locus_tag="PB779_002722"
     CDS             3688..4038
                     /locus_tag="PB779_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HDE0740205.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(4062..4676)
                     /locus_tag="PB779_002723"
     CDS             complement(4062..4676)
                     /locus_tag="PB779_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDE0740206.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
BASE COUNT         1729 a          790 c          941 g         1439 t
ORIGIN      
        1 aacgggtagg cttactgtct ttcttggcaa atttacaatc aagccatttg cagatatagt
       61 gcgcggctac ttctgccatg attgcaaaaa caaaatcaaa aagaattttc aaacctataa
      121 cctcctcccc ttgccagatt aggccggggt agcagacagc aagactatta tagcataatt
      181 gaaatatcca aatgattgga tttttgctat aattttagcg aggtgattgt gatgaacaaa
      241 tatgttggtt tgcttgataa aatccgagta ataaaaacgc aaccgttatt ggttcgcttt
      301 actttacaaa cgattcatga atcgattaat tgtgtagttg cagatattga aattatcgat
      361 aaattgctaa ttatggatga tggaaaatac aatattgccg tcacaggtca cttcaataaa
      421 cgaaatcagc tagttattgc tagcatgtat gttagaaatc ccgatcattt tacgcgatcg
      481 atgggcatat aaaaaaagaa gagttgcaat cctaatgtag gactgcagct ctttttgttt
      541 tacatagaaa caagaaaaat gaaaaggcct ttttaggaag gcgcgagcgc cttctcaatt
      601 gaaaaacctc tctcactcca accgccaccg ccgttcgaga agaaaggaag tgaacgttgc
      661 acgttcacta agataaaggg tcttgcaaag caagacaaaa tagaaaaaac ttcctctcac
      721 caaaaggttc gttcctgttc gttatctctt tattgatttg ccagaccggc aacaagttgc
      781 cttttatcac caaaaagcga caaggacaag ggtaaatggc acgctgcgcg cccttgtcct
      841 tgtcgctttt cgttgattca ttctggccaa caaatcaata aagaaagaac taacgaaagg
      901 aagtaaaacc tttcctaaga ggaggcagaa tcaatcatgc gaaagaaatt tgattattgg
      961 ggtgttccct tcagcgaatt attcccaaac tatcatgcac cacatactgt cgaatgcgat
     1021 tgtggacaaa gagcgaaatg tatcaaaagc tatcgtttgt atcaatgtcc aacatgcgga
     1081 aaaaaataca ccttgtctta tggcgattat attttgattg atgagaaagg aaagaaacgc
     1141 tgatgaaaac ataacataaa ttattgactg taaaagaagt cgttcaaatt ttggtggaca
     1201 aagaagtcat ttctgaaaaa gtagcagaag ctttacttat tccgcggtac tggacgatag
     1261 aaaccccttt agtagaggat gcaccgacta tgctatttga agacctagtg aagattgcag
     1321 gatatgaact gcattatcaa gaaaacatgg aaacttatga aaacgaatat tggttaacca
     1381 aattagagaa ctaaaaagga gaaaaaaata tggctcaaaa ttactatgac gaatttgtca
     1441 aattaccttt ggataaaatg gcacaaaaaa tggaggatat gacattccta taccatgaga
     1501 cacgtgttcc aaaaaaacat tataaggaaa gattgtcggt agctgtggaa gaaatgattg
     1561 aatcaggtgt cgaaatgaat ctcattgcga cgtactatcg aacactggaa gaactgaaaa
     1621 aacaaaatgc aaaatggttt ttccaagcct tactatgctt ggaagtaggt gtcaaaccaa
     1681 gcactattaa accttctgaa tatcaagctt tagaactaac gtatgggaaa tttgtcgaaa
     1741 cgaaaaaagc caagactgtt tcaagtgaat ggttagatta ttttgaaaat atcaataagt
     1801 atggcgccta ttacaccatg aaaaaggagg acaacgaaaa tgaataaggt gatttatcaa
     1861 ctaacaacgg aagatgtgtc acacttttta acaaacaaag aacatttgaa tgaagtaatc
     1921 agacggattc aaaaagactt tagttgtatg gaagaaatga agtactttat tcaaagagtc
     1981 gaagaacaat tgtatttgga aagtgaaacg agtcaaacga aggtcacagt cagcaataat
     2041 tatttagacg tgtataaaca tcgtcctgaa acggtaaaaa aaggaacgga gcttctacga
     2101 ctagaaacag aaaaatacat catgaatgtt tacctagaaa ggagtgaact ggtcgaaaac
     2161 tttgtcagct gcacgatttg caggaaacac tattactcag aatcagaata ttattcaatt
     2221 tttgagagca tggaattaat ggaagaagaa atggaagagc taaacagcaa aaatgcgacg
     2281 atagacgatt attatcttgt atttactaga tttttgacgt gtggaacgga atctatcgtg
     2341 ttaatgggaa tggattatga actcgctgta cccgaagcat ttttgaggga atatgtagaa
     2401 gaagtagata acccaggcga cgactggtac acgactttaa ctgatttttt agatacctac
     2461 acttacgacg atacagaaga aatccaaaat gaacttgacc gtaaacgaat gccatatcaa
     2521 cgatttgaaa ggaaaaaaag gcaataatca tttataccga aaagtgagaa tgtgtgaaat
     2581 aagaacaaaa accttgaaat taagggaatg gttcttattt cgcaccaatc gctccaaccg
     2641 cccccgccgc ttaggtggtg cgaaataagc gggcaaagcc cgataaccta agagaaagaa
     2701 ggagatccat atgaataaaa tcattcctct gttgttcgta ctgtgtattg gcgagatact
     2761 tatgcgtcat ggtgcagctg tacatttaaa cttcgtagta ttcttaggaa tactagtatt
     2821 ttgtttgatt ttttggcgct ttgtgttagc ccttgtgagt ctactattca agttgattgc
     2881 agccatattt ttcatagggt tatttcgatg aaaggagaga gtactaatgc caattgcaat
     2941 aggaaataaa cggttacccg tgacattaga tgaaaagaga caaaaagaat tgcagcaact
     3001 aaagcagaag tacggaaaaa gtgaatctaa gattatgtgt attgcgttag atctattgat
     3061 cgcgcaagaa aaagcaggat ttgatatacc agcactaaaa aagtgacgtc acttttcatt
     3121 tgaagaaaca aaagtgatag cacttaattg ttcctactat ttagaatatt ttctatgtcc
     3181 tttttattcc attttgtatc aataactatg aaatctttaa agtatccaga tcaatttttt
     3241 tcttacctga ttctaaagat tttgttttct taaacatatt atgatttcct ttcgactatt
     3301 ttcatataaa tgttaacata gtttatggat tcatggaatg ttaatctaat ttaatagaaa
     3361 aggataatta agtatatacg ttttttctta tgtatgttat actatgtata tacagaaaga
     3421 ggtgtctact atggaaatgt tacctataaa aaaatgggga aatagtaatg gccttagatt
     3481 gccaaagtat attatggaat atcttggaat tcatacagaa gacaaagtga agataataca
     3541 agaagaagta aacggtcaga agcggctaat tatcgaagcg gctaatatag aaaatgaatt
     3601 aacaattgaa cagttatttg aaaattacac tgatgaaaga aatcatgtga cgattcaaaa
     3661 tttaggtgaa gcagtaggta atgaaaaatg gtgagaaaac ctagacaagg cgatattcta
     3721 ttattgaata cagcacctcg atctggacac gaacagacag gtaaaagacc ttatattgtt
     3781 ttaagtcatg atattattgc ggattatagt aacgttgtta cagttgctcc aatttctagt
     3841 acaactagaa actatccgct atatgtaaat ataaactcag aatatgaaat gaagacaaca
     3901 ggaaaagtat tattagatca actaacgaca attgattatg aagccagaga gtgtattttt
     3961 ttggaaaaag cgcatgatag tttagttgag gagttattga tgaaagttag aacagttttt
     4021 caaaaagtaa gcaaataaaa tagaaacagc agcatgatca actattcgtg attgaccatg
     4081 ctgtcttttt ttattctata tacggtttgt ctcgtaacat tgtagtcttt tgcaatctta
     4141 gcgatcgcaa cacctttttt tagatcctca acgatgtttt tataaacaag acgacgttgg
     4201 ggatcttttg cattggcact gtatagctta ggacgtcctt tataaacacc gttcgctttt
     4261 gcaatcttaa tgccttgtgc ctgacgtcgt ttagattcgg tacgttcttg ttcagcgatc
     4321 atggccaaaa tttgaatgat caaatcttta atgaatttat ccaggagagg attgccaatt
     4381 gcttcggcca tgatcggtag acttgtgatg atcagctgca catttttctt cttcaagtaa
     4441 ttgactgaag cgatgatctc gtcgtaattt cttccaagtc gatcaatagc ttccacaata
     4501 aaaatatctt gatctcggac gaaatccagt gcttcttgaa aaacaggtcg atgagtaatc
     4561 gttgcgccag attgtttctc aatgaaaatt ctctctgcac cgaatttttt catttcttca
     4621 atctgccgtt gttcattttg atcgatggat gagacacgta tgtatgcaac tctcaaaatt
     4681 tttacctact ttctgcaact atttaaaaaa caccctaatc atacacgaga aaaccagatt
     4741 tttcaatgtc gcggtcgtgt ctagttaggg tataccttat atagacaaaa actaatgatg
     4801 gaggaaatag tatgtgtcac ttttcttttt aaatggcaat attttttgta aataaatgtc
     4861 aatcaagaaa atttaaacga ttatgacatt aaaaatata
//
LOCUS       DAMEEU010000121         4897 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.126, whole genome shotgun sequence.
ACCESSION   DAMEEU010000121 DAMEEU010000000
VERSION     DAMEEU010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4897
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.126"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(81..1889)
                     /gene="pepF"
                     /locus_tag="PB779_002724"
     CDS             complement(81..1889)
                     /gene="pepF"
                     /locus_tag="PB779_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HDE0740207.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
     gene            complement(2065..3063)
                     /locus_tag="PB779_002725"
     CDS             complement(2065..3063)
                     /locus_tag="PB779_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HDE0740208.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            complement(3289..3942)
                     /locus_tag="PB779_002726"
     CDS             complement(3289..3942)
                     /locus_tag="PB779_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HDE0740209.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            complement(4274..4672)
                     /gene="spxA"
                     /locus_tag="PB779_002727"
     CDS             complement(4274..4672)
                     /gene="spxA"
                     /locus_tag="PB779_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HDE0740210.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
BASE COUNT         1447 a         1020 c          753 g         1677 t
ORIGIN      
        1 aaaaaaatac gtcgactccc ttacaagaga gccgacgtat ttttttcgtt tctattcgag
       61 aaaatcaaaa atagaaagcc ttataaacga tcgatcaatt cttctaattc atttagacgt
      121 tgttcaaaca tcgacattgc atcttcaata tatgcagcct gtgtcatatc aactcctgct
      181 tttttcatta cttccacagg ataatcgctg ttacctgctt ttaggtaagc caagtagttc
      241 tctagtgcct ctggttcctg gtttagtatt ttcttcgcca gtgctgaagc agcagaaaag
      301 ccagtcgagt attggaaaac atagtaatta taataaaaat gcggtatccg tgaccattcg
      361 aatttaattt ctgggtcttc ttcgactgct ggaccataat attttgcatt caatttacca
      421 taactatcac ttaggtattc actagtcaat ggcacacctt tttcatcttc cgtatgcatg
      481 aaatgctcga attcagcgaa ttgtgtctgg cggaaaactg ttcctttaaa cccatccaag
      541 taatggttga gtacataagc ccgtacacga gggtcttttt ctgtttccaa taaatactcc
      601 gttaggatat tttcattcgt tgtcgaagca atttctgcta aaaagatgga gtagtcgccg
      661 tacacataag gctggttcga acgagtgaaa taactatgaa cactatgtcc catttcgtgg
      721 acaagcgtaa atagctgatc cagcgtatca tgccaattca ataaaatata tggatttgtg
      781 tcatagcttc ccgaagaata agcaccgctt cgtttccctt tattttcgac aacatcgatc
      841 caacgttcag agaatgcttt ttctacgatg gccatgtatt cttcacccat tggtttcagt
      901 gcttctaaag ctttttcttt tgcttcttcg tacgtaaagg taattggagc ttcccctaag
      961 accggtgtat aaagatcata catgtgcagt ttttccactt ctaataaacg tttccgtaat
     1021 tccatgtatc gatgtaacaa aggcaaatgc ttgtttacca cgtctaccaa agtatcgtat
     1081 acactttcag gaatatgatt attgctcaaa gacgcttctc tggcagagct gtaattacgg
     1141 actttcgctt taaaattatg tccttttata tgtgtgccta aagtagaagc aaatgtattt
     1201 ctaaattgtt cgtaaacact gtacaacccc ttaaatgctg cttcgcgcac ccttcgatcc
     1261 gtgctttcta gcaactgacc atacacgcca tgagataatt ggactatttc accattttct
     1321 ccttcaatcg ttggaaaaac tagatctgca ttattcaaaa cagcaaatgt atcacttgaa
     1381 gcatcaaaga tttcacctgc tccagcaaga agagattcct gctcagcaga taagacatgg
     1441 gctcgattat ctactatttg ctggatataa tggcgataga cttccaattt tggttcttct
     1501 ttgaaatatt gccaaatctg gtcatctgac aattgcaata tttctggttc aaaccaggaa
     1561 acggcttcac taactttcga aaacagactg cttgctcttg cataaagcgc ttggtaatct
     1621 gtatttccag tgtcttgatc gtttttaagg tgcgcatata cataaatgac ttcagtttgg
     1681 cgataaaccc tcaatacgaa ttcaatcgca tttaaaaatt gagaagcgcc ttgatcaagt
     1741 gttcctttgt gtttttcaga ttgttttaac tcttctgata attccaaata tttctcatca
     1801 aactcttggt cgcttgaaaa gatcttggtc aagtcccaag ttaaattttc aggcaattct
     1861 tctcgttttg gcaactgctt tacttccatg aaatccactc cttttcttcc cttagctcta
     1921 tctatcaaaa tagatcatag tctaacatcc acatgtcaca gcatctaact tttctactca
     1981 ttcatgtgtc tgcttccatc aattttagca taactaaatc ttgttttaca tagaaaaccg
     2041 attcctagcc tatttttata cttactattt tttcaaagaa gacaagtgta tgcattcgtt
     2101 aaaaaactgc tgatagacca tctcttcatc aatcatagga aaaagccatt cccttttatg
     2161 ttcttttatt tggcaaagcc atgagttgaa atcaggaact ttctggtttt ccaaggcttc
     2221 ttcgtacaac attcgataaa gaaaaacctg ttcttgtaaa taaaagaaaa accgactttt
     2281 ttgatagatc cacgatgata gatgcaaaag atgtttatga cgcaagtagc attgttcttg
     2341 tatggatact gtattctttt gcttgtgaat aagttggcgt gtcagccatt tcttcccatc
     2401 ttcactcact ttttctattt ttttcatttg gttcatttta atttcgttac tagtgaatat
     2461 ttctttaagg tccctactag aaaaagtcca gcagctactg caaaaggaaa tatgccctga
     2521 tacagtctct gtaatatgat gatacaaata aagcttttgt ttcttgagat cagctttcca
     2581 gcaatgcact cctctttttc tattatagta gcagcaactt ttttctatca atgagaattg
     2641 cgattgtcca agaaaagaat taccaagtat ccaccatact tggtaactgt tattcaaata
     2701 attttgggtt ctttcaataa atctctggtg agacagtcta gaacattgga tttctattgc
     2761 tagattcgcc aacaaaatat ccggcctttg ccgcaacctc ggcaaatagg cttccaaaaa
     2821 tactggttct actgactgtc ccagccaatc catgaagcat tcctttaact gtaagtgctc
     2881 ttttgattct ctttcactaa agaccgaaca gttatctgat ttttgatggg caaaatgagc
     2941 acattttttc tttccctttt tcaaaatcac tctttttcga cagccacgac aataatattt
     3001 ctttcctttt tctgcatgtt tagcaaaaca gcacttatta tattcattca ttgcaagcag
     3061 catttttctc cctctgaact tatttacgtc taagaattta tttacacgaa aaaagagggc
     3121 gtgaaaaagc tattctgcat caagtaataa gaacagctaa acaaaaatag ttcccaatat
     3181 ttttcgtttg gttgggcttg ttaccgcaga tgcaagcttt tgaacacatt tatacgaaaa
     3241 aaagactgcg acacaatttt tgtcacagtc tcttactata atgctgattt atacaaaata
     3301 aaatttcgtt cgctcgatag cattacgcgc catcagacat tgtccatatt cattcaatgt
     3361 ttctggtgta cgatcgctct tttcagcaaa ctccaaaatt cgagcaatct gattctctac
     3421 atccgcttgg ttgagatttt ccatccagaa gtgaacgact aggtaatagc gctcttcgaa
     3481 taaatacaaa tcagtccaag cagactctag ttcgacatct gttgcaagtt ggatcacttg
     3541 ttcaaaatct tcaaaagcaa aagttgcttg tctttcctgt tcttctaggg cgcttccaga
     3601 taattcttcc tccggatcgc tgccaataat ctgctgacga agaaagtcac tcacatcttc
     3661 tgaatcaaca gtagaatctt ctgattgaga aatttcttca tccggaagat ttttactgat
     3721 aaacagttct aatccgtctc cttttggcaa aacttggaaa gtgacagctt cgcttcctcg
     3781 gaactcctct tcgatatcaa cttcttccaa aatactataa aagaaatttt cgatttcttt
     3841 gtgattgcca agtaaatcca aaaatgaaac gccccgttcc tctaaatctt catgaccaat
     3901 tagtacacgg atcgtatttt cattaatatg ttccatttcc attttgctac acctcacttt
     3961 gccacaatgt ttaatataga ttcattgtag cgaaatcagc ttaaatgtaa agaaaaaaaa
     4021 tctcgctgtt aagcgaattt aataaaacca gcggattttt caacctttca agctatctta
     4081 tttaactata acatttttgg cagacgaata ctatatagcc gacttttcag ctaattttcc
     4141 ctctctattt ttcgtgcaat catcatcttc tactaccttt ttatacatct aatcaagaat
     4201 actttttgta aaaacaaaaa aacttggaaa aactatcttt gtaatagtct tttccaagtt
     4261 tcgtattatc cttctataat ccagccatca attgtgcttg acgtaattct aattgtcgta
     4321 catcgcgcgg taggaaccga cgaatttcat cttcattaaa accaacttgc agacgtttat
     4381 catcaatcat gattggacgg cgaagcaatc caggattgtt ttgcacaagt tccaataatt
     4441 cttgtaacgg cagatcatct aaatccatgt tcagtttttg gaatactttg gaacgtgtcg
     4501 agatgatttc ttctgttccg tcttctgtca tttgtaaaat cgcttttaat tcagaactgt
     4561 tcaatggttc tgaaaaaata ttacgttcaa caaatggaat ctgatgttct tgcaaccacg
     4621 cacgagcctt tctgcaggaa gtacaacttg gggaagtata taatgttaac aacgtgcacc
     4681 actccttttc gtgataagaa tcactttttt gtaacagaag atcataataa tctcccatct
     4741 gtttctatta tacataatca acttttaaat agctaccttt ttttcataat ttttttaaaa
     4801 aaatgaaagt tatctaaggt taatatacag taaaaccagc attctcgctt tttttatcat
     4861 ttaaaaatta gagttttcaa atctaattca aattttc
//
LOCUS       DAMEEU010000122         4807 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.127, whole genome shotgun sequence.
ACCESSION   DAMEEU010000122 DAMEEU010000000
VERSION     DAMEEU010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4807)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4807)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4807
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.127"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="PB779_002728"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="PB779_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HDE0740211.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="PB779_002729"
     CDS             complement(3250..3768)
                     /locus_tag="PB779_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HDE0740212.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1579 a          786 c          729 g         1713 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcgtta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaatgtt gatcgtcagc aaggagctaa aaaatacgaa
     3961 tatatttctt ttgtagtaaa atcggactgg tttgcatatc attttcttcg taaatatcaa
     4021 aatcatgtta actactatca attactaata aaaactacca ctttaagcgt taagaactgt
     4081 taagtttagt taagtgagga tagttcacaa aatccattgt taaacttcac gaaagtggta
     4141 aaactcaaaa tgctttatat aggattacag catcgctctt tcttcgattg cgcgttgggt
     4201 aaaaaatatt atgaagtaaa aattgacgat gacacgttcc ttacggctca tcagatgaaa
     4261 cagctacaaa aacgaaatga tcaactcgaa gaaaatttaa ttctaaaaaa gcgattgcca
     4321 tattcacgcc tcgctcgacg aactattaaa ggtcaagatt tacctgaaga tcatcctttt
     4381 taggaaattg aagcttttta tgttgcacaa tgcatttata atactacaat gatgttttca
     4441 ccagatattc ttctagggtg cggtgtaatg aaacagatac acttgcaaaa gaaaattcac
     4501 cgcgaattta ctaaaattat gaataattat gttaatcttc cgaaattttt ttccaaaatt
     4561 aagggatcaa gctggtgtta tagattgttt aaggttggca aaaaaataac ttctttttaa
     4621 acaattatag aaaaccgata ctctgttaag ttggttgaca cggtgtcgat ttttatgact
     4681 ttcttattct gaaacttcac taacggacag tacctaaaaa gtctatagta tggacgttta
     4741 cgagtactat tttatcaaaa atgctgctca tttcaactta tatgttttag tgaactaccc
     4801 ccactta
//
LOCUS       DAMEEU010000123         4747 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.128, whole genome shotgun sequence.
ACCESSION   DAMEEU010000123 DAMEEU010000000
VERSION     DAMEEU010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4747)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4747)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4747
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.128"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            86..802
                     /locus_tag="PB779_002730"
     CDS             86..802
                     /locus_tag="PB779_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HDE0740213.1"
                     /translation="MVDNYERKNILKKKSIGCRMKIVAIVPMKLNNKRLPQKNTKAFT
                     NGKPLCYYILSTLLKVKQIDKVYVYCSNPDIKEFIPEGVTFLKRSSSLDQDTTSITQV
                     LAGFTKEVEADVYVMTHTTAPFISEKSIEKGLDAVLTGEYDSAFAAKKLQDFLWKDGE
                     PFNYELDNIPRTQDLPPLYEETSGFYIYNRNVMTELHRRIGKKPCIVEVGEIESVDID
                     EAEDFMIADAIYNHLILQGS"
     gene            821..2404
                     /locus_tag="PB779_002731"
     CDS             821..2404
                     /locus_tag="PB779_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldolase catalytic domain-containing protein"
                     /protein_id="HDE0740214.1"
                     /translation="MNNVQILDCTLRDGGYCNNWEFGFDNTKKIISGLIESGIEIIEC
                     GFLTNKTVYNKNVTKYTTLEELAQIIPEKREGKLFVAMMNYGEYNIEDLPDYDGSSID
                     GIRIAFHKKNCNEALKLCREIKKKGYLVFVQAMVSLNYTDEEFLAVIKNVNQFKPYAF
                     YIVDSFGMMKGKDLTRLFYMIEHNLEKDIQIGFHSHNNMQLAYSNAQKLITVQTNRSL
                     IIDSSVYGMGRGAGNLNTELFVEYLNDNAGKKYQLKPLLYIIDEILNSFYQKSYWGYS
                     LPNYISAVHNAHPNYASYLSYKNTLTIEAMNEIFEMMDEEKKVSYDKQYIEDLYYKYM
                     ETGKIQEEYMEELRKFLSDKKILLIAPGKSSVDEVERIKEFVTKEEVVIISVNFEYSH
                     IDIDYVFLSNLRRFHELPKESRTKCIVTSNIQASDVYLRTSYKKLLSEREVVRDNAGL
                     MAIRFLADMNVDEIFLAGFDGYSHNEDENYGEQSMEIITKFALLDAMNVQMRDELSEL
                     AKKVKVTFLTDPRWVRIDK"
     gene            2539..3117
                     /locus_tag="PB779_002732"
     CDS             2539..3117
                     /locus_tag="PB779_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740215.1"
                     /translation="MISILCIVAYHANLRLNYNADGIIVHGSLTANQIFLNYIGIWGQ
                     LGVNCFIFISAYFLSEKRNIHFENVLGIVLECIFYSVLVYGILCACGIETFSLNSFVK
                     EILSFALGRYWFITSYLALYILSPYLNIMLNNLEKLQLQKISMLLFIGVCCYRMLFKT
                     SLFGDCAVLIALYVICYTLKKTIIIFLRDTES"
     gene            3063..3581
                     /locus_tag="PB779_002733"
     CDS             3063..3581
                     /locus_tag="PB779_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740216.1"
                     /translation="MLYTEKNDNNIFERHRIIGTIVCITVIPLLISIGILFKFIPNAM
                     VNQMVHIGSPLMVIASIFLFYVFKNFSFYSKYINKLARTSLGVYILHENHYFIDGMKS
                     RGLIWDGIFGLGKRFLDRDFWIWFIIAVVVVCIICMAIDVVREKFERQIFKIKSVKNL
                     CKLMNHVINIYP"
     gene            3589..4629
                     /locus_tag="PB779_002734"
     CDS             3589..4629
                     /locus_tag="PB779_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HDE0740217.1"
                     /translation="MRRKEVKVISFGELLLRLAAPGYSKLFQRDSLETTFCGGEANVA
                     VSLAIFGYQSEFITKLPDSDVGYAAANALRYFGVNVDNIIFGEGRMGLYYLEKGAAQR
                     PSKVIYDRKFSAISLADSDEFKWKEILNDANWFHWTGINPALSENLFETSLDACQAAK
                     KRGITISCDLNYRSKLWTSEEAKEKMEQILPLVDICICNEEDAEKVLGIKAEHTNINS
                     GELNKDGYVQVAREIHKKFGCRYVATTLRRSYSASRNGWSAMLYEAEKDKAYFSTEYN
                     IQIVDRVGGGDSFSAGIIYALCENMSGQKAIEFATASSCLKHTIEGDFNRTTIEDVYN
                     LMNSGGNGRVLR"
BASE COUNT         1746 a          527 c          944 g         1530 t
ORIGIN      
        1 gaggaagaaa cattatttca atgattaaga gtcgagagca caaacggtag acgatgttat
       61 ttttataaaa agatataatt tattaatggt cgataattat gaaaggaaaa atattcttaa
      121 aaaaaagagt ataggatgtc gtatgaaaat agtcgctata gtaccaatga agttaaataa
      181 caaaagattg ccacaaaaaa acacgaaagc ttttaccaat ggaaaaccat tgtgttatta
      241 tatactttca acacttttaa aagtaaaaca gattgataaa gtgtatgtct attgtagtaa
      301 cccagatatt aaagaattta taccagaagg tgtaacattt ttaaagagat ctagttcctt
      361 agatcaggat acaacgagta ttacacaggt attagccggt ttcacaaaag aagtagaggc
      421 tgatgtatat gtaatgacac acacaacagc accatttatt agcgaaaaat ctattgaaaa
      481 aggactagat gccgtgctga caggagaata tgattctgca tttgctgcaa aaaaattgca
      541 agatttctta tggaaagacg gtgaaccatt taattatgaa ttggacaata ttcctagaac
      601 acaggatttg ccgcctttat acgaagaaac tagtggattt tatatttata atcgcaatgt
      661 gatgaccgag ttgcatagaa gaattgggaa aaaaccttgc atagttgaag taggtgagat
      721 tgagtcagtt gatattgatg aagccgagga ttttatgatt gctgatgcga tttataatca
      781 tcttatttta caaggtagtt aagacagggg gaaggttagg atgaacaatg tacagatttt
      841 agattgcaca cttagagatg ggggctattg taacaattgg gaatttggat ttgataatac
      901 aaaaaaaatt atttctggac ttatagaatc aggaattgag attatagaat gtgggtttct
      961 cacaaataaa acagtataca ataaaaatgt tacaaaatat acgaccttag aagaattagc
     1021 acagataatt cctgaaaaaa gagaaggaaa attatttgta gcaatgatga actatggcga
     1081 atataatata gaggatcttc cagattatga tggttcatct attgatggaa ttaggattgc
     1141 gtttcataaa aaaaattgca atgaagcgtt gaaattatgt cgtgagataa agaaaaaagg
     1201 ctacttagtt tttgttcaag ctatggtatc tctcaattat acagatgaag agtttttagc
     1261 agtaataaaa aatgtgaatc agtttaaacc atacgctttt tatattgttg atagttttgg
     1321 aatgatgaaa ggaaaagatt taactcgtct tttttacatg attgagcata atctagaaaa
     1381 agatatacag ataggttttc actcacataa taacatgcag cttgcatatt ctaatgcaca
     1441 aaaacttata accgtacaaa caaatcgaag cctgattatt gattcttcgg tgtacggaat
     1501 gggaagagga gcaggtaatc ttaacacaga actatttgta gaatatttga atgataatgc
     1561 aggaaaaaaa tatcaattaa aaccattatt atatataatt gatgaaatac taaatagttt
     1621 ctatcagaag agttattggg gatattcatt accaaactat atttcagcag ttcataatgc
     1681 tcatcctaat tatgcaagct atctgtcata taagaatact ttaacaattg aagcaatgaa
     1741 tgaaatattc gaaatgatgg atgaagaaaa aaaggtatct tatgataaac aatatataga
     1801 agatttatac tacaaatata tggaaactgg gaaaatacag gaggaatata tggaagaact
     1861 gagaaaattt ctctcagaca aaaaaattct actgattgca ccaggaaaaa gttctgtaga
     1921 tgaggtagaa agaataaaag agtttgttac caaagaagaa gtcgtaataa ttagtgtaaa
     1981 ttttgaatat tctcatatag atatagatta cgtattttta agtaatttaa gacgttttca
     2041 tgaattaccg aaagaaagca gaactaaatg tattgttaca tcaaatatac aagcatcgga
     2101 tgtatattta cggacgagtt ataaaaagtt gttatctgaa agggaagttg taagagacaa
     2161 tgcaggatta atggcaatta gatttttagc cgatatgaat gtggatgaaa tattcttagc
     2221 tggatttgat ggatattcac ataatgaaga tgagaattat ggtgagcaat ccatggaaat
     2281 tataacaaaa tttgcattat tagatgcaat gaacgtgcaa atgagagatg aattgtcaga
     2341 attagctaaa aaagtaaagg tgacattttt aacggatcca cgttgggttc gaattgataa
     2401 gtagtagtaa taatgttttt aaaattttga taaagagata gtgagagaat aaaaatgggt
     2461 aaagtcttaa ataaaaaaga agaaaaatat ttaagggccg atggggcgag atgaaactct
     2521 aattttgaac ttttaagaat catttctata ttgtgtattg ttgcttacca tgctaatttg
     2581 cgtttaaatt ataatgcaga cggaattata gtacatggtt cattaactgc taaccagatt
     2641 ttcttgaatt atattggtat ttggggtcag ctaggagtta attgttttat atttatttcg
     2701 gcatattttt taagtgagaa aagaaacatt cactttgaaa atgttttggg aattgtatta
     2761 gaatgtattt tttatagtgt attagtttat ggaattcttt gtgcatgtgg aatagaaaca
     2821 ttttcattga acagctttgt aaaagaaata ttatcatttg ctctaggtag atattggttt
     2881 attacatcct atttagcatt gtatattcta agtccgtatt taaatatcat gcttaacaat
     2941 ctggaaaaac ttcagttgca aaaaataagt atgttattgt ttataggtgt atgctgttat
     3001 cgtatgttat ttaaaacatc tttgtttggg gattgtgctg ttttaattgc actatatgtc
     3061 atatgttata cactgaaaaa aacgataata atatttttga gagacacaga atcataggaa
     3121 caattgtatg tataacagtt ataccacttc tcatatccat aggaatactt ttcaaattta
     3181 taccaaatgc aatggttaac cagatggttc atattggttc tccattgatg gttatagcaa
     3241 gtatattttt attttatgta tttaaaaatt tttcatttta cagtaagtat ataaataaac
     3301 ttgcgagaac cagtttaggg gtatatattt tacatgaaaa tcattatttc attgatggta
     3361 tgaagtctag aggcttaata tgggatggga tatttggatt aggcaaaagg tttttagata
     3421 gggatttttg gatttggttt ataattgcag ttgtagttgt gtgcataatt tgcatggcta
     3481 tcgatgttgt aagagaaaaa tttgaaagac agatttttaa aattaagagt gtaaagaacc
     3541 tgtgtaaact tatgaatcat gttataaata tatacccata attaataaat gaggagaaaa
     3601 gaagtgaaag ttatatcatt cggagaatta ttattgagac ttgcagcacc cggttattca
     3661 aagttatttc aaagagatag tttggagact acattctgcg gaggggaagc taatgtagcg
     3721 gtatccttag caatatttgg atatcaatca gaatttataa caaagcttcc ggattcagat
     3781 gttggatatg cggcagctaa tgctttgcgt tattttggag taaatgttga taatattata
     3841 tttggagagg gacgcatggg actgtattat ttagaaaaag gagcagctca gagaccatct
     3901 aaagtaattt atgacagaaa attttctgca atttcgttag ctgatagtga tgaatttaag
     3961 tggaaggaga tcctaaacga tgcaaattgg tttcattgga cagggataaa tccagcattg
     4021 tctgagaatc tctttgagac gtccttagat gcatgtcagg ctgccaaaaa aagaggtata
     4081 acaatttctt gtgatttaaa ttatcgatcc aagctttgga catcagagga agcaaaagaa
     4141 aagatggaac agatactacc attggttgat atttgtattt gtaatgaaga agatgcagaa
     4201 aaagtgctag gaattaaagc tgagcataca aatattaata gtggagaatt aaataaagat
     4261 ggctatgtgc aggtggctag ggagattcac aagaagtttg gatgtaggta tgtagctaca
     4321 actctgcgta gaagttattc ggcaagtaga aatggttgga gtgcaatgtt atacgaagca
     4381 gaaaaagata aagcgtattt ttccacagaa tacaacatac aaattgttga tcgcgttggt
     4441 ggtggagaca gcttttctgc tggtataata tatgcgttat gtgaaaatat gtccggacaa
     4501 aaggctattg aatttgcgac tgcatctagt tgtttaaaac atactataga aggtgatttt
     4561 aatcgaacta caattgagga tgtatataat ttaatgaata gcggtggaaa tggtcgcgtg
     4621 ttgcgttagt caacatataa agataaatca cagtaatttt tatggtgatt atctgtctta
     4681 gtagtgatta gaataacgtg aaaataaatt gttgagcgtt tatactgttt tgaaaaataa
     4741 atttaac
//
LOCUS       DAMEEU010000124         4744 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.129, whole genome shotgun sequence.
ACCESSION   DAMEEU010000124 DAMEEU010000000
VERSION     DAMEEU010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4744)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4744)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4744
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.129"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(28..1026)
                     /locus_tag="PB779_002735"
     CDS             complement(28..1026)
                     /locus_tag="PB779_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HDE0740218.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1101..1397)
                     /locus_tag="PB779_002736"
     CDS             complement(1101..1397)
                     /locus_tag="PB779_002736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740219.1"
                     /translation="MAKLIVLGGLIYGGYWLYQYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1390..1683)
                     /locus_tag="PB779_002737"
     CDS             complement(1390..1683)
                     /locus_tag="PB779_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740220.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1829..2380)
                     /locus_tag="PB779_002738"
     CDS             complement(1829..2380)
                     /locus_tag="PB779_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HDE0740221.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2554..2853)
                     /locus_tag="PB779_002739"
     CDS             complement(2554..2853)
                     /locus_tag="PB779_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HDE0740222.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEMGMLPEDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2880..3146)
                     /locus_tag="PB779_002740"
     CDS             complement(2880..3146)
                     /locus_tag="PB779_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HDE0740223.1"
                     /translation="MDSLPVELQALCWNLIDQNVQKQFPLDYLQIFEFSTEKGNQKLV
                     HRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY"
     gene            3493..4176
                     /locus_tag="PB779_002741"
     CDS             3493..4176
                     /locus_tag="PB779_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740224.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIK
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4213..4710)
                     /locus_tag="PB779_002742"
     CDS             complement(4213..4710)
                     /locus_tag="PB779_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0740225.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1404 a          907 c          694 g         1739 t
ORIGIN      
        1 tttttctttg ataaataata ttttcaatta tttaatcatt tgaaaattgt tagtcattcc
       61 aatacgttga gaaattcttc catctgtata aacacgaaat tgttttccac cagccatggt
      121 cgtgtttcca tcatcatccg ttacaatatt aattgaatag tagcttccat tttcatcttg
      181 cattagatct ttcatatatt catttgtgct aattaaatta gtatttgata catttttatc
      241 aggagaatca tacaaccata aagctttatt atttagcaca gattctttag cagcttccca
      301 acttgaaatt cctgaactac ttgtagattg tgtcgttgta gttgttgctt gttgagtaga
      361 ttcttctact actggtgttt gaggagtttg tccattcaca atatcactga aaccttgttt
      421 taactgttga ttttgagttt cgttaaagta cagataatta ttttcattac cttgattttg
      481 ttgcgttaaa taaactttag gttgtccatt ttgaaaaccg aaaaagtaaa catgctgccc
      541 taaatattct ccagtttcta catcagaata aactgctact aaattgaaat ctgcatgacc
      601 agttccatct tctgaccatt gtacggtaac tggtgcttca ttgattgcca ttttccaatc
      661 gccattaatc acggcttgtg gtaaaggagt gccatacaga cttacattat tctgaagatt
      721 gtagctttta tattcttgac ctaatgtctt tccccattgt gtgacaaaag tttctaattt
      781 ggaagcttta ttcgtatccc acaaagtatt cttaacctct tcagaagaag attcagtgat
      841 tgaacttgca cttgtttcca cagattgctt catttctgtt gtagtttgtt cagttgattg
      901 cgttttactt tttttagtct caattgttgt atcagtttct atagtcgctt tagtcctcgt
      961 attctcagat gtacaaccag tgaataaaat tcccattcct attagtaata acagccattt
     1021 tttcattata tttccccctt tcaatttctc cctcacgtac ttattctatc agacaattaa
     1081 ttgatctaaa tggtaatctt ttaatcgatt ctttcccaat aatgtcgata gcccgtatgg
     1141 cagcggtctc ttccttgagg actctcagat ggattaaaac tagtagaaat ttcccttcca
     1201 catcctctac agcgataagt tctcattatt tttgggctat tagtattatt tttcttagtt
     1261 agagctatga gtccaactat gattacccca actgtcttaa ttacttttcc tttatctata
     1321 ttcggatgcg caagcatata ttgatataac caatatccac cgtaaattaa accacctaat
     1381 acaatcagct tagccatgta ctcgtctcct ttctttttgt ttaattactt tttgaatcca
     1441 tcttgcagag aaaccataaa cttctgtcaa ttgacggata tctacagttt tttcctgttc
     1501 tatcatgttt tcgattcttt ttctaactaa ctcacgatcg tacattttca ttggaaaaga
     1561 aatctgttgc cctcgaaaag caagataaaa ttgatagagc aattctgaat ccagttccat
     1621 ttcctcaaaa aagtcattca tacttttata agagttactc aaacaagttt catcaatctc
     1681 catctacaca ccccctgtta ttttttacat aatgaaaata gcatattact gggtacattg
     1741 ataattcata taacatgtat catcacatgt atttttaaag tcaaaaagca tgtaaaacta
     1801 cttataagta acatgagaaa ataaaatgtt atttttcttg aaataataat tgactatctg
     1861 ccaattgcca ttcattacga acatgaatac ttagtgggtg ggataactta ccttctgcat
     1921 ttatcaatac tttggtcatc ttcttttgtt tcgcactcaa ttgatcgtaa atagtctttg
     1981 cttgttcata agccacttga ctcgtcgctg taatcgaacc acaagcaaaa ataatggtat
     2041 tgattttctt ttctgtaaaa acagtcgtta atatttccaa agattgttca tcatttcctc
     2101 gaagaaatac ccgaggactt ttcgcttttg tgtacgaaaa aagattcaca gcaataaaac
     2161 cagtaaatcc taattgtcgg atattctttt cgattaataa catactcaaa tcattcgtaa
     2221 atggttctgt atctgttgga cgaatagtaa tgactactgc taatttatct tccgcttctt
     2281 ttcctttgat cgcccattgt cgtttgaaaa catagcgatg ggtatgatga ggatctcgcc
     2341 aaacttctgt ttgtgtggtc actaattctt tttcaatcat ctctttttct cctatgctat
     2401 tttttgttca agcacttcaa ttaccattgc cgttataagt gtcaatacta gttgaaaata
     2461 tttcatattc tttctccttt tttcttcaga atttgatgaa tcgcggtaag gatatcttct
     2521 aaacatttcg caatcattct caaataatcg atcttattca tccgttcctc caatctgact
     2581 ccaaaccaat cgtccttcta ccagtaaccc acgaacaaat tctcgctggc tggtaatatc
     2641 tgtaatgaaa taaactacat agtcttttcc atcttctggt gcgcaataaa tataaagatg
     2701 tgtcatcact aaacgtggta gatgaacatc ttcaggaagc atacccattt caatttcctc
     2761 tttttccatc gtaacggatt catagcccca ctcttcagaa gcagtgacca gctgtgcaca
     2821 cttttccagt acttcgatag ccgtttctaa caagtccttt cgttcctttc ttttagatac
     2881 tagtattctt ctggtaataa catcgtttga tactcacccg aatcaatggc ccatattttt
     2941 tgagacactg atttcaaacg aagcttaggt gaaatcagat actcttttct ttcttccggt
     3001 tcttcttgac gatgaaccaa cttttgattt cctttttccg tagaaaattc aaaaatttga
     3061 agatagtcta aaggaaattg cttttgaacg ttttgatcga ttagattcca acataaagct
     3121 tgtaattcca ccggcaaact gtccattact ccctttgtga cataacgtta tcctttattt
     3181 tgaaacattt cttttccctc ctttgccata aaaatagccc aatcttctat taaagaagat
     3241 tgggcttcat ggatataata tatatttgta aataaagtta attcagttat aattatcaaa
     3301 actacacaat tattaaagtt tttcatatct ctttgtttag taagtttttc taaatcttaa
     3361 cccgtggtgc tagttaattt tttcctagag gaaaatgtct aaacatgttg gtaaatcaac
     3421 aaaaaaacgc atatagtagt ctcaaaactc ccaagaaatg aggactattt aacaaactac
     3481 gatggttacg tcgtgacaac tgaacatttt gacttagcca atcctgttac taaagtcgat
     3541 gatatccccg attatgaaat gtacagtcaa acaatcgata gcttaaataa gcgttttggc
     3601 aatcgtgttt taaaaggcat caaaatcggt tacatcgctt ctgaaaagga tcggatcatc
     3661 gactatttag ccgataaaga ttacgattta aaattactca gtgtgcatca taatgggcaa
     3721 tttgattatt tagatgacga agtcaaagat atggatcctg ctattgtgat tcctcagtat
     3781 tttgcacaac tttcagaagc actagttgtt atagaagcag atgtctttgc tcattttgac
     3841 tatggttttc gggtatttgg tctatccgtt gctgaattta aacaatatga agcgcagttt
     3901 ttaccgattc tagatcaagt aatcaaaaat aaattggcat tcgaattaaa tgctaagagc
     3961 gcttacttgt atgacaattt agcgttatat gaatatgtca tcgatttata tctttcacgt
     4021 ggtggtacct tgtttagtgt tggatcagat gggcattacc ttgaacattt ccgtttccat
     4081 ttcgatgatc tttttgctct gttaaaagca aatggtgtga cggaattagc gatttatcaa
     4141 aaaggaaagc gaattatggt tccattacca gtctaaaaaa acgtcctcag catcaaaagt
     4201 gaggacgttt ttttagattt ctttttctaa aatcggacaa atacgatctt gttttcctaa
     4261 aggaaaatgt ttgatcccga tttttttaaa tccatgacgt tcataaaaac gaatacctgc
     4321 atgatttttt tcataaacag tcaaacgtaa ataacgtttt tgtttcgttt tagcataacg
     4381 attcgcttca tcgagtaacc gttgccctaa ccctttgttt tgataatctt tgagcagata
     4441 gagccgttga atctctatag catctttttc atcattgact ttcatataac caatgagtat
     4501 ttgatgatcc ttaataccaa taaatttact ggttgactgt gccaattcta ctgccaatat
     4561 ttcagttgtc aattgtgtct gtaaatatcc ttgcatatca agtggatctg cgccatcgat
     4621 aaacgattca taaaaactga caacacttac aacttgtaaa gcatctagat catcataatc
     4681 taaatacgct agtgtgattt gattgttcat ctaactcctc cttttgacat agtatactat
     4741 aaat
//
LOCUS       DAMEEU010000125         4587 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.130, whole genome shotgun sequence.
ACCESSION   DAMEEU010000125 DAMEEU010000000
VERSION     DAMEEU010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4587
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.130"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            186..2855
                     /locus_tag="PB779_002743"
     CDS             186..2855
                     /locus_tag="PB779_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HDE0740226.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEVSFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEKPRNTHRRRRRK"
     gene            complement(2946..3566)
                     /locus_tag="PB779_002744"
     CDS             complement(2946..3566)
                     /locus_tag="PB779_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HDE0740227.1"
                     /translation="MFLINATDEILSVNKVFYTVPAEKMSRVSSDINTITSRIGLTKA
                     MHMVLKYNQEDPPVPKTYEAIDLIIVDEIDRLKLQHLEQLRDIYDRNDLAMVLIGMPG
                     IEKRLSRYPQLYSRIGFAHEFDNLSKDETHHILEYKWADLGIDIKLEDFSDYEAITTI
                     IKITKGNFRLIHRLFAQIDRILRINQMDKITVEVVEAARDSLVIGI"
     gene            3680..4219
                     /locus_tag="PB779_002745"
     CDS             3680..4219
                     /locus_tag="PB779_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740228.1"
                     /translation="MKKLFSALFILLFGFIGIGTSGNIVKASTMVEQTSEMAKTFSQL
                     TPEEQSYFKSKGFSDKDTFYTQKIEPQDPKTRFSANVLRLTASTKKITNTQGRTEYII
                     TSPNSAMYRISTRLSLGSAKSYTQTVNLANSYGYGGGMYFTFTGKRQYYSVKLAMQVY
                     NTFGVGSVSCTAGGLTIGK"
     gene            4216..4554
                     /locus_tag="PB779_002746"
     CDS             4216..4554
                     /locus_tag="PB779_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenic metallochaperone ArsD family protein"
                     /protein_id="HDE0740229.1"
                     /translation="MIISYYVLNRSDDEGLFVFQSLHEDTMLKEFYNRIKNKQIETNL
                     YFLSDSILPFISNPKILNLLQTKDLKSLPIIVIDEEIVKYGAYLSVEELEKLTNIGMS
                     IQEDNGVHGT"
BASE COUNT         1419 a          790 c          860 g         1518 t
ORIGIN      
        1 atttttaagg gtgggacttt tgattcctac cctttttttg cgtttatttt tgttatacga
       61 acaaattatg aagttattta ttctaaattt tatttttttg tgaaaattag actcttttta
      121 agcagagaaa aacaaggata tgataaactg aatacaactt catagaaatt tggtggaaaa
      181 taaatatgaa aaaaaattta aagtcattct ttagagaaaa cggacgctac gcagcagcta
      241 gtttcctgat tccgtttttg attttagcac ttgtttatct aagtatcggg atctatcctg
      301 gaagcagcag aagtattttg gcaagtgatg ccttttcaca gttttctaat tttcatgcca
      361 gcttccgaaa tgttcttctt ggaaagcaaa gtatttttta tacatggaat gcttctctag
      421 gattgaatta tttatcttta atttcttact atctaggcgg gatcttcacg ccactggtgt
      481 tcttttttcc aaaccagatg atgccagatg cactgtatgt tctgactttg cttaaggtcg
      541 gctgtgccgg attggctttt tggtttcttg cacgtacgtt caagattcct cgctgggggc
      601 atgttgcact tagcgtcagt tacgcattga tctcatttat cactgcacat tcggagatca
      661 tcatgtggct ggatgcattt gtttatcttc cattagtgat tttggggatt catcgtgtta
      721 tggatcttaa acggccgaaa cttttattta tcagttattt actcttgttt ttatccagtt
      781 tttatatggg ttttatgatt ggcgtatttt ctttcttata ttttatcgcc cgtctattga
      841 caaactggtc agaatataaa aaaacgattg ttccttatgg tatcacttct ttactggcag
      901 gcggcgcttc aatgatcatt gtattgccag cagtgctgga tcttcggtca aatggcgagg
      961 cactgagtca gatcactacg ttgaaaacag aagcgacttc ttatctggat ctaatcatga
     1021 aaaatatgat tggtgtttat gacacgacaa aatacggatc gattccgttc gtttacgcag
     1081 gtctgctacc attagtcctc tgtctgtttt attttgccag tcggaaagta ccgttgaaaa
     1141 ataaattttt gtacggcagt cttttcgcca tacttatcgc aagtttctat cttgttccat
     1201 tgaatttgtt ctggcatggt atgcatgcac cgaatatgtt tttattccgt tatgcctatc
     1261 tgttctcttt cttagtgctc ctgcttgcag gaaaaggatg ggaaaagata gaacaagacg
     1321 atcgtgggct gttgttagga atcattttgg tcgtagctgc tctctttgcg gtggcatggg
     1381 gcatcaaacc tgaaggaagc tacacctatg tgacgatgac ttcctttgta ttgacagtgg
     1441 ttttcttagg gatttatgct tttgctgtgg gattttatca gcataaaaaa ctttcattca
     1501 atcatctgag tatattgtta ttattgatca tgtctgctga agcactggtc aatacgaaca
     1561 gtatgatcca tggcattctt gatgattgga attatgcttc ccgcagttta tatactgatc
     1621 cttatcctga cttgaaagct cttgtaaatg aaacaaaaaa agattccgac tcgttttacc
     1681 gcttggaaaa tctggatcca gtatctgcaa acgattcgat caactatggt tacagtggta
     1741 tcagtttgtt ttcttctata agaaatcgta attcttcctc ttacctggat aaattaggtt
     1801 tccgttcaag agggacaaat ttgaatatcc gttataacaa taatactttg ctaatggatg
     1861 ggtttacagg aatcaaatat aacatttcta aaaacgaaag cacgttcagt aaatatggct
     1921 tccgccaagc tggtcaaagt ggcgactata cactgtatca gaatgtcaat gcattgccac
     1981 tagcatttac tgcaccgttg tccgttaatg atgttgagca gccagtgaca gataatttga
     2041 ccagtcagac aaacttgatc aatacattgt ctggtttaaa tgaacagtat tttacattct
     2101 atacacctac tttgaagaat cagttgaata cgacgatcac aaagacaacg actggcgtca
     2161 cttactcaga aacagcagat aaccagccaa aagagctcac ttgggaagtc catgtgcctg
     2221 caaatacaca agcttactta agtttgttcc caaccaattt tgcacaatta gaaagttcta
     2281 gtgcgacgat cactgtcaat ggtacatcgc gaaaaacgca aatcaacatt tctggtcaat
     2341 actatgatct tggctattat cctcaagaga caacagtgac atttactgca agtttttatg
     2401 gaacgaaaga agtaagtttc atggagccta aagtcgttgg tctagatgtt gtagcctatc
     2461 aagccgcaat gaatcagatc aaagaaaaag gtgtcgaaat ggaagccact ggcagaaaag
     2521 cttctgggac tgtaaatacc gctgaagatt ccatgttggt gacaactatt ccttatgaca
     2581 aaggatggaa agctaaaatt gatgggaaac cagtcaaggt cagcaatttc aaagacgcat
     2641 tcttgatgat aaaagttcca gcaggtaaac atactgtcac tttcagttac ttgcctgaag
     2701 gatttacgat aggtgcaatc ctttttgtcc tatgtattgc attgtttatt ctttatgtct
     2761 ggtaccttga ccgcaatcgc cccttttatg gcacgattga tccagcaata gaagaaaaac
     2821 cgcgaaatac acacagaaga agacgaagaa aataaagaaa cgatggaatc tgtgtcactc
     2881 ttctatttaa atggcaaaaa tttcaatctt taaatgacaa aaaccacctg atttttggtg
     2941 gttttttata tacctatgac taaactatct cttgctgctt cgacaacttc tacagtgatc
     3001 ttatccattt gattgattct taaaatccga tcaatctgcg caaataaacg atgaataagc
     3061 ctaaaatttc cttttgtgat cttaatgata gttgtgatag cctcataatc agaaaaatct
     3121 tctagcttga tatcaattcc taaatctgcc catttgtatt ccaaaatatg atgtgtttcg
     3181 tccttactaa ggttatcaaa ttcatgtgca aatcctatgc gagagtaaag ctgcggataa
     3241 cgagacaatc ttttttcaat accaggcata ccgataagaa ccattgccag atcatttcta
     3301 tcgtaaatat ctcttagctg ttctaaatgc tgaagcttta aacgatcaat ttcatcgaca
     3361 ataattaagt caattgcttc ataggtttta ggcacaggag gatcttcttg attgtatttt
     3421 agtaccatat gcattgcttt agtcagacct attctactag ttattgtgtt aatatccgaa
     3481 ctgacacgag acatcttttc agctggtaca gtataaaaaa ctttatttac acttaatatt
     3541 tcatctgttg catttatcaa gaacaagaaa aagtctgaat attcaaaaaa aataacggtg
     3601 tacattttta aaaggagatg tataatcgag atttagaaag cgttttcctc aaaatttaat
     3661 gaattaggaa gtgattacta tgaaaaaatt atttagcgca ctttttattc tgttatttgg
     3721 ctttattggt attgggactt ctggaaatat agttaaagct agcacgatgg ttgaacaaac
     3781 aagtgaaatg gcaaaaactt ttagtcaatt aacaccagaa gaacaaagtt acttcaaatc
     3841 caaaggattt agtgataaag atacttttta cactcaaaag atagagcctc aagatccgaa
     3901 aacacgtttt tctgcaaatg tattgcggtt aaccgcatct actaaaaaaa ttactaatac
     3961 gcaggggcgg acagaatata ttataacaag tcccaattcg gcgatgtatc gtatttctac
     4021 acgcttgagt ttaggtagtg caaaatcata tactcaaaca gtaaatctag ctaattctta
     4081 tggttatggt ggaggaatgt attttacatt tactgggaaa agacaatatt acagtgtaaa
     4141 attagctatg caagtttata atacatttgg tgtagggtca gtctcttgca ctgcgggagg
     4201 attgacaata ggaaaatgat aatttcttac tatgtcttaa atagaagtga tgatgaagga
     4261 ctcttcgttt ttcaatcatt acatgaggat acgatgctaa aagagtttta taatcggatt
     4321 aagaataaac agatagaaac aaatttatat tttttaagtg actctatctt gccttttatt
     4381 agcaacccta aaattcttaa cttgttgcag acaaaagatt tgaaaagttt accgattatt
     4441 gtcattgatg aggaaattgt aaaatatggc gcttatctaa gcgtagaaga attagaaaaa
     4501 ttaactaaca ttggaatgag tattcaggag gataatgggg tacatggaac atagaatgaa
     4561 tatgcacagt tgagaacgga atttgac
//
LOCUS       DAMEEU010000126         4585 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.131, whole genome shotgun sequence.
ACCESSION   DAMEEU010000126 DAMEEU010000000
VERSION     DAMEEU010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4585
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.131"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(1016..1306)
                     /locus_tag="PB779_002747"
     CDS             complement(1016..1306)
                     /locus_tag="PB779_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740230.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            1708..1944
                     /locus_tag="PB779_002748"
     CDS             1708..1944
                     /locus_tag="PB779_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740231.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            1951..3903
                     /locus_tag="PB779_002749"
     CDS             1951..3903
                     /locus_tag="PB779_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HDE0740232.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(3975..4472)
                     /gene="dfrG"
                     /locus_tag="PB779_002750"
     CDS             complement(3975..4472)
                     /gene="dfrG"
                     /locus_tag="PB779_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HDE0740233.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
BASE COUNT         1568 a          805 c          756 g         1456 t
ORIGIN      
        1 acatacttgc aaagtaatac tacaattcct aacataatcg tagaatttaa taatttccat
       61 agcataaagt gtttagaaaa gaacattaag aatagttcta taataattct tgaactccat
      121 gtcttataat gttctatcga agcacccaaa tagccaagtt catctaatct acttgcataa
      181 actacgtcat ccgctctcat agtcggcata tacatattaa agagtaaaaa gataccccaa
      241 atccctatta gtaacaagat cagttctttg ttattcgtta tttttctatt atgtttgttc
      301 atttttatac tccttcttat atttcctaat agagtataac atagctttaa gcattactta
      361 aagataactt aaaagttatc ttttaaatac ttaattgtta aataccttat ttgatgcaaa
      421 agaaatctac gatagtcaac aaaaaaattt tcattatatc cagaaaaatt tttcttagtt
      481 aaggacctat ggattgcagt aatgcagaat tcgtcgaata aactgccaaa gacatacaat
      541 catattgctt ttaaaattga cgaacaagat atagattcgt ttgtctcaaa aatccaaatg
      601 ttaggtttaa ctgtcgaacc aggacgttct cgtgtgaaag gcgaggcttc ttcaatttac
      661 ttttacgact atgataatca cctcttcgag ttacataccg gtactctcca ggaacgttta
      721 aaatcctaca attccactac ctgagactag taatgactag tctcttttta tggcctctga
      781 tccccccatt gagcgaatac taatagggct tcgaattgat ctgttcaatc tttaagcaat
      841 atccctcaaa tgagtttgga aagtttagtg attcatcaca aatacttaaa tacatgtagt
      901 tatatataga ttgaggttct tgtgagcgta tgctcgtgtg ggttcaaatc ccatcgtctg
      961 catccatctt tccaaaacaa gcggctagga catttttgtc tcagccgctt gttttctagt
     1021 ttattctttc atcttgtcgg accttttttc ttgggtatag acttttctca tattctacca
     1081 caattttggg tttccctaac acatgatagg atctcacaac aaattgcttt ctattattat
     1141 aataacctgt aacgactaac ttcatccctt cgtctacttc agctaggaag ttcaaactat
     1201 gggaagcaat caaacaattg accccattta aactgaaacg gatcaacggt ctggcactaa
     1261 cttgcaaagt acggatctta tctactgttc catatttttt ctccataacc ttcacctcaa
     1321 taccattata cgaacataca ttccctttgt aaagaagaaa ctctgtttta tctttttgac
     1381 tttttgtcta ttacctttct taaaatcata ttggcacttc ctgcgaagat gaaggacatg
     1441 tactaaaaaa aagaggcagc agtatagatt taagtagttc agttttggag tacaaaaagt
     1501 gaaaatgtaa acctaaatga gtatcaaatt gcaactgaat ttgatactcg ttttttattg
     1561 ttaaatcaac gtttgttgtt aatttacacc acaaaatgta agttaaaatg tatataaaaa
     1621 tgcgaacgtg aaataattat tgtaggaatg caaattggtg tgttaaaatg gttacaattt
     1681 actaagcaaa aaggggtgca ttttcctatg caatttcttg agccaaaaaa taagaacgct
     1741 aagtctgtgg attgggaaat atcagagcaa gtaagggtga tagttaagca atacgctgaa
     1801 tatgcagagc gtactgaaag cgaagcagtg gatgaattct tattgaacat tttagacgat
     1861 aagaagttta ttgaatggat tgccaacaag cgaagtaata agcggattgt tgaaaaaatg
     1921 ggtatcaaag atagagtggg ttgatagaca atgaccaagc ttaaaagatt agccacgaag
     1981 gaagatgaaa ttgtagatgt taaaattccg atttcaaacg aagaattaaa agatagggct
     2041 aaacaatatg atttattaac tccaaaacga tttgcaacaa ggtataacaa aatgttgttc
     2101 ttgccaacgt cttttaaatg gaacggttct gaatatccca ttcaatataa ttactgcatc
     2161 aatccgtttt gttgtaattt tgggaaagaa cagcacaaat tcaaagatgt aaaagggaaa
     2221 ccaagtcgat ataaaatgac tggtagttcc aaagataaag gtcataaagg tatgtactgc
     2281 aatgacaatc ctattggcag aggtgtatcg caaaactgta cagtaacccc tttatctaat
     2341 tggtctgttg ttgaagaaat taaacgcctt atagaaatca atagcatcca agatgttgag
     2401 ccagattatc aatttcataa agaaggctgc tcggaagaag aatcaacccc attcaatgag
     2461 ccgaagcaat tttacaaaag ggggaaaagt aggggcaaat ctcaacgcta tcaatgtaag
     2521 gcgtgtaaga agttcactaa tgttctacca aaaagagaag aaaccactac ttatcaccaa
     2581 caaaagaaca ccattcttcc aatgttcgct aagatggttg ttggaagggt ttcagtcagt
     2641 cgtacttgtg atattttagg aattggagtt ggaacctact atcataagct ggagtggctg
     2701 tataggcgtt gtttggagtt tttagaacga tatgagacac aaccccttca aacaaagaaa
     2761 tttaacgaga tgtggcttaa tacggacaag atgcactact acctaaataa cgtccgtaag
     2821 aaaggacaag gttcaaagaa atatacgggg tttgaagacc ttaatatgca aacgtatata
     2881 gttgtatctg ctgaggtctt atcaagatat gtgttccgtt ctgatgttgc ctatgattgg
     2941 aatatttcaa tggatgaatt aaatgaagat acaagaaaat tcaaagaaga ccatctcaat
     3001 acttttagtc gtaaaaatga taggttagat tggtcttatt atccacaaga accatccgct
     3061 aacgatagcg aaaataggaa tgcttatctt cacgaattag ggaaaattac taataggagt
     3121 agatttgtcg atggtttaaa tgttgatgct ccttatacta caactgctca ctattggtta
     3181 attaaacaaa tggttaatgc cgacgaatgg cgaatgatta gtgatgatga cttctctatt
     3241 agaaacgcct tttatagagt attcacgaaa gaattaaggt tgagcgatgc acatcatttt
     3301 atttgccaag ttaacaagac gaaaagcaga aaacaatgct taaaagaatt cggacaagca
     3361 aaagcagaac tgctcgattg gggagatatc agaggattca aaacaaagtt tctacggact
     3421 ttggcatctc attatctaac tgaattacta acaagtcatc aattccacga agaggctatt
     3481 agtaaagatg gagaaagata tcgcaaatat gccgataacc ctatcaaaca tccattagcc
     3541 actaaggata aaggatttta ttcagttgat tgtagaacgg atttatctgc tctggaacca
     3601 aacgaaatcg caaagatgct attaaatgtt aatgaccatt cgaccaatag ctttattcaa
     3661 cagataagac gttatatatc atctcttgaa agaccattaa caacagctcg tggtgataag
     3721 aagagctata tttacgctaa cttcaatccg aagtatgctc aatttgcgat tacaattcta
     3781 agaacttact acaacttttg tcgccctttt aaatcagcgg ataaaaaggt tttgacacct
     3841 gctcaaagat tagggattac agataaacaa tttgattgga aagatataat ttatttcaaa
     3901 tgacaaaaag agcttggagt aatcccaagc tcttgtgctt tatctttact gttcttcttc
     3961 aattaacgca cccgttaact caataagttt tttctttcat atacatgaaa atagtagtta
     4021 tacggatttt tatcattctt tatccctttt tgggcaaata cctcattcca ttcctcataa
     4081 ttcacttctg gaaaaaaagt atctccttcg aattcatgat gtatttttgt gatgtacatt
     4141 ttctcaacat aagggaaaaa caaattataa atctgttctc ctccgaaaat aaaaatttct
     4201 tcttcgtttt tacataactc aaaaacatct tctattgaat gaacaatttc acaaccatta
     4261 aaggtaaacc ccttatctct cgtcagaata atatttcttc tgtcaggtaa ggctcttccg
     4321 attgattcaa ggttcttcct acctaatatt atcggatgtc cctttgtagt atttttaaca
     4381 tattcccagt ccttgggaat cctccaagga atgtcattct ctttgccaat cactctattc
     4441 ttatccatcg cagcaatcaa agaaactttc atttataaca cagccttttt aactaattta
     4501 ccatctaatt tcttatttct atcaaaaaac cttttctcat tatcctgccc gttagttgaa
     4561 taagcaattt tttctataag ttata
//
LOCUS       DAMEEU010000127         4459 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.132, whole genome shotgun sequence.
ACCESSION   DAMEEU010000127 DAMEEU010000000
VERSION     DAMEEU010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.132"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..744)
                     /locus_tag="PB779_002751"
     CDS             complement(<1..744)
                     /locus_tag="PB779_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element ISEfa7 family transposase"
                     /protein_id="HDE0740234.1"
                     /translation="MQGVIAMMSKNNTNGRNQFAMLTIDDLVPQDHLVRKIDAALDFE
                     FIYPIVEATYSDLGRPSIDPVILIKLVFIQYLFGIRSMRQTIKEVDTNVAYRWFLGYS
                     FEEKIPHFSTFGKNYVRRFRETTVFEDIFAYILEQAVKAGFVTEDNLYLDSTHIKANA
                     NKHKFTKEMTHDEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPE
                     SGYYVKGEREKQFAYSAHTSCDDNGFILST"
     gene            complement(716..1915)
                     /locus_tag="PB779_002752"
     CDS             complement(716..1915)
                     /locus_tag="PB779_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDE0740235.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDIEGKVLSMYARGMSQCDIAATVEDIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKVRGVEDVFFISMDGVSGLKEGAKAIFPSVIVQRCIVHLVRNALRYLPSK
                     DYKEVCRDMKKFYSASSLNAAHAAFDSFQNRWSHYSGAVDVCKRNFSHVEQLFDYGSA
                     IRKIMYTTNAVESIHSSFRKVTKKGVFSNENAQTVDKVHFMDDVYSLFFYNRFMKTNA
                     RSDSYDV"
     gene            complement(2045..3421)
                     /locus_tag="PB779_002753"
     CDS             complement(2045..3421)
                     /locus_tag="PB779_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0740236.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGGVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            complement(3421..4077)
                     /locus_tag="PB779_002754"
     CDS             complement(3421..4077)
                     /locus_tag="PB779_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HDE0740237.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            complement(4087..>4459)
                     /locus_tag="PB779_002755"
     CDS             complement(4087..>4459)
                     /locus_tag="PB779_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HDE0740238.1"
                     /translation="SLILILWLRERIYEIGIFLSIGTSKIQIIMQFIFELIFISIPSI
                     ISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQSYLILISIIVLS
                     VVFASSLMLIKKPKEILSKIS"
BASE COUNT         1375 a          833 c          629 g         1622 t
ORIGIN      
        1 tgtgctaaga ataaatccat tgtcgtcgca tgaagtatgg gcagaataag caaattgttt
       61 ttctcgttcg cctttgacgt agtagccgct ttccggatca gctttactta tttttctttc
      121 tttcagcttc acttcctttt ctaagtccaa agtaaaaggg cgttttccag cctctattcg
      181 ttgacgattg atctcatctt ctaattcatc ctgataggct ttcgcttcat catgggtcat
      241 ttctttcgta aacttatgtt tattggcgtt agctttgatg tgggtagaat ccagatacaa
      301 attatcctct gttacaaaac ctgctttaac tgcttgttct aaaatatagg caaaaatatc
      361 ctcaaacacc gtcgtttctc taaatcggcg aacataattc tttccaaaag ttgagaaatg
      421 ggggattttc tcctcgaagg agtagcctaa aaaccagcgg taagcgacat tggtatcgac
      481 ttccttaatg gtttgtcgca tggaacggat accgaataaa tactgaataa acaccaattt
      541 gatcagaatc actggatcga tacttgggcg acctaaatcg gagtaagtgg cttcgacgat
      601 tggataaata aattcaaaat caagcgcggc atcaatcttt cgaacgagat gatcttgagg
      661 aactagatca tcaatcgtaa gcatcgcaaa ttgatttcta ccattcgtat tgtttttaga
      721 catcatagct atcactcctt gcattcgttt tcataaatct attataaaag aaaagactgt
      781 agacatcatc cataaaatgg actttgtcta cagtctgcgc attctcatta gagaacactc
      841 ccttttttgt gacttttctg aagctagagt gaatactttc aactgcatta gtagtgtaca
      901 tgatttttct aatggcgctg ccataatcaa agagttgttc aacatgagaa aagtttcgtt
      961 tgcatacatc tactgcacca gaataatgag accaccgatt ttgaaaactg tcgaaggcag
     1021 cgtgtgcagc gtttaaagaa gaagcactgt agaatttttt catgtctcga cagacttcct
     1081 tataatcctt acttgggagg tatcgtaacg catttcgaac aagatgaaca atacagcgct
     1141 gcacaatgac agaaggaaaa attgcttttg cgccttcttt gagaccggaa acaccgtcca
     1201 tcgaaatgaa aaaaacatct tctacaccac gtactttcag ttcatcaaat acttgcatcc
     1261 agcgattttt agattctgtt tgattgagcc ataggcctaa aatctccttg tttcctttaa
     1321 gatcatagcc aagaatggtg tacacagcat attctttagc ttcatagttt tcgcgtaaag
     1381 tgacgtacat acaatcaacg aatagaaatg cataacactt ggctaatggc cgagcttgcc
     1441 attcttccaa ttcaggaagg acggcatccg tgatatcaga aatcatttcg tgggaaatat
     1501 caaagccgta aatatcttca acggttgcgg cgatatcgca ttgactcatt cctcgtgcat
     1561 acatggaaag aaccttacct tcgatgtcgg agacatctcg ttttctatta ggaatcaact
     1621 caggttcaaa agaagcctcc cggtctctgg gaacatcaat gtttacttta ccaaagctcg
     1681 ttttaagcgt cttattgcca taaccgtttc gtcgattgtc atgtttcttt ggctctttag
     1741 aatgggcgtc ataccctaaa tggttattca attctccttg aagcattttt tcaaataagg
     1801 gaccaaacac atcttttaaa acatcttgca tatcctctac agattcgggt tgataagtat
     1861 tcaaaatgga ttcagctaac ttctcagcat caggatttct tttctttcta gccatcgtgt
     1921 aatcacctct tgatcttatt ttagaaaaat aaaaaccgtg aagcaaccac ccgcctagga
     1981 ttgatggtta cttacacggt ttatattaca ctctcatttt tggtgctaaa aagcaccgaa
     2041 aattttaatt attgtcaatt aataattctt ttggattcct tcttaatata ttgaatgaag
     2101 aaataatcaa tgatacaaga agtactaaac tcataaatat aactacataa atcatgaatt
     2161 taggtaatac attgatatct aaacttgata atgtcttgtt aaatccttca gcttctgccc
     2221 caccacctaa ttggctagat gcagattgtt tagctatttg tttagctata tcaccagtaa
     2281 ccttattcaa tatattattc ccaagcttgt cagctgtata ttgagctaag aaataggaac
     2341 caacgaatgc ggggattgat ataaatacca tctcaattag gaattgacca aaaatttcta
     2401 attttgatat acctaatgat agtaatactg ctatttcttt ctttctagca ttcatccata
     2461 agaataataa taatgaaact acaactcctg caaatattaa tgagccaaaa aataatttat
     2521 ttgaaattga gtaaatacct gatatagatt gttgtaatgc agggtaattt gatgaacttt
     2581 taatcaaatt atattctctc caatttatat ctaatttccc aagatctttt attacactat
     2641 caagattctt atcacctttt acaaagaatg ttgcatcttg gtatacagct gtatcttcgg
     2701 tattaccata aactttagca gctgtatgaa tatcagtgat taatgtattt tcgtatagtt
     2761 cttgtgctgc acttactcca ccgctattat gcccatcgaa tagaccttta atttctactt
     2821 ctactgtttc atctgcacct ttctcattat cagcatcaaa taaattagat tttattttta
     2881 tcttatctcc aactttaagg ttattttttt cagctaaatc tttatgcatt aagattttat
     2941 ttttatcttc attttctaaa tgctttcctt ctactaattt atatgcttct gatacaaatt
     3001 ttgtttcttt tgttgagtcg ttaaccccag ttaacataac tgttctttta aaattctttg
     3061 ctctttcagg tgattgattc gcaagagtct cttgagtttc aataatatca taatcaacta
     3121 aatctgcaac actgtttatt ctttttacat aggagtctat actatctgtt tgagatatct
     3181 ttttaatatc ttcacctttt acatttcccc cacctctagg tgttcctgga tttacttgtc
     3241 tatttatctc catagaaaaa ctatttgtta tattagcaaa tgtttctttt gaagctctgt
     3301 ccgtagcatc tttaatagat aaactaatga gacttaaagt tgacatagat aaaataacta
     3361 atatgataat taatgatttt aaactttttc tagttacata agcaaatgca ttttttatca
     3421 ttattcaacc tccaaattca ttttatttac ttttttcaac tttttaccac ttagttctaa
     3481 aatgatatcc gcagaatctg ctacttcctt actatgtgtt acaactatta cacatttatt
     3541 tctatcttta gctaatgtct ttaatatatt aattatttct ccagcagtaa cactgtctag
     3601 attaccagta ggctcatcag ctagtattat tggagcatct gataccaatg ctctagcaat
     3661 agctactctt tgttgctgtc caccagataa tttcataaca tttcttttta tttgtttttt
     3721 atctaaacct agttcaaaca agatactttc atctgctgat ttatttacta atctaatatt
     3781 ttcaattggt gataaataat ctattaaatt atagttttga aatactaaag atatattatt
     3841 ttttctatga ttactatatc ctttattttg tatatcttca ttcttaaaca atatttttcc
     3901 tgtttgaggt ttatcaagtc cagcaagtaa ggaaagaagt gtagattttc ctgttcctga
     3961 ctttcctact atcgcataaa acttcccaag ttcaaatttt tgatttactc ctgacaaaac
     4021 tttttcttta gaatttgcat aactatatgc tacattcttt atttctaata tatccattat
     4081 tctctcctaa cttatttttg ataagatttc tttaggcttc ttgattaaca ttaatgaaga
     4141 agcaaataca actgataaaa caataatact tattaatatt aaataacttt gtccaagtgt
     4201 tgttatattt gacataaaac tactattatt tattaaactt ccaccggaaa tcattgaatc
     4261 ctctgagtta atgaatccat ctacaattac ttttagtaat acatttccta aaaataagga
     4321 agatattata cttggtatcg atatgaatat taactcgaat ataaattgca ttataatttg
     4381 tatcttagat gttccaatag ataagaatat acctatttca taaattcttt cccttaacca
     4441 tagaatcaag attaatgaa
//
LOCUS       DAMEEU010000128         4350 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.133, whole genome shotgun sequence.
ACCESSION   DAMEEU010000128 DAMEEU010000000
VERSION     DAMEEU010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4350)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4350)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4350
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.133"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..1015
                     /locus_tag="PB779_002756"
     CDS             <1..1015
                     /locus_tag="PB779_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HDE0740239.1"
                     /translation="DFNEMFLLYMFKTRYYLFGPFRANNIDKDFFKLKMNNLNVAMAD
                     RERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTGNLSKTIEQIKI
                     DNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDTIRSEKN
                     YSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIVYYTKEI
                     GKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMHITIYNY
                     ISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLGLVDNFN
                     NIS"
     gene            1160..1465
                     /locus_tag="PB779_002757"
     CDS             1160..1465
                     /locus_tag="PB779_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740240.1"
                     /translation="MLNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDA
                     KISSYLFFLIHDEFMDYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            2082..>4350
                     /gene="esp"
                     /locus_tag="PB779_002758"
     CDS             2082..>4350
                     /gene="esp"
                     /locus_tag="PB779_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HDE0740241.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLVGVGLVLGTT
                     ELVQAQDEISPSTPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEEPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSASAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGKKVADLAIERRKDHENYGVGSITDNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSILDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDI"
BASE COUNT         1594 a          587 c          810 g         1359 t
ORIGIN      
        1 tgattttaat gagatgtttc ttctatacat gtttaaaacc agatattact tatttggtcc
       61 atttagagca aataatattg ataaagattt ttttaaacta aaaatgaaca atttgaatgt
      121 tgcaatggct gatagagaac gactctataa ttcattgcaa aatttgactt tgtattcttt
      181 aggagacatt cgagatattc tgattttagt tcattatttt tttactggaa aaatagaaga
      241 tctattccat gaaccgttaa ttgaatatac aggaaatcta agtaaaacta tcgagcaaat
      301 caaaatagat aatctgttat cacaaaatta cgatccagaa atatatctgt ttctttatga
      361 aaataaaata ctggaatatg ttaaaaatgg agatattcga aatttagaaa acatggtttt
      421 taatctgagt aatggaataa ttccaagtgt tagtggagat acgattcggt ctgaaaaaaa
      481 ttattctatc attgtttttg aaaagttagc acaaacgtct ataacattag gaatggatat
      541 aatagaagcg tatcaaagta gagatgcttt gatacaagaa aacgaattag ctgtatcgtt
      601 acctgaggtc ttaaaagtga gggattctgg gattgtttat tatactaagg aaatcggaaa
      661 aactaagata gagcatcttt ctcccttaat ttcttctgtc gttcaattca tcggcttaaa
      721 tatctataaa agaattactg taaaggaaat agctaattat ttttctgtaa gtgaaactaa
      781 attaagagaa agctttaaga atgaaatgca tattacgatt tataattata tctctaagcg
      841 aaaaatttct acggctaaaa taatgttgaa atcaaaccat actatcagtg aagtttcttt
      901 aggtttagga ttttcagatt cttcacactt ttcgagagta ttcaaaaagt acgcaggtgt
      961 atctcctaag caatatcaat taggtttagt ggataatttc aacaacatta gctgagaggt
     1021 tttattttat tatgagacta tatcatttac gtagtttgga ggagttgagg aaattggatt
     1081 ttaacaaaaa attttttggg aaatttctga tttgagttgt ttcgtagaat ctgagcgtct
     1141 aagtaatggt aataatagtg tgttaaatga atatgacaaa gtagtaatta ataaagtaaa
     1201 aagtttatgt gaagaagcta gagaatctat cagtcatatt aatggtagca attttaagca
     1261 aacattattt aatctgatta agctagatgc taaaatatca agttatttat tctttttaat
     1321 acatgatgaa tttatggatt atcaaaaatt ggatcagtta attgaaagag aaagctggga
     1381 agattattac gtgggtctaa ctttttcaga aaagttaaac aactacaagt taatagatta
     1441 taagtatttg agtgaaagca attaattatt catgtagagt actagacact ttaaatatgg
     1501 acaattcaat tataaagaaa aagaatcaat aatttaatga ggctgtgaca aatgtcattt
     1561 tttgtttcgc taaaaacgag tgaaaaaatg ttgataactc caatcattcg tttaagattc
     1621 taggaatcat tcaggaatgc tgtgaaaccg atactttata attataaaga aggtgatttc
     1681 aaattccgaa gaaggaattt gaagtcacct ttttacttat gtcacagtct cattcagtaa
     1741 tgcgggataa ggctccttat tccgctattt gaatactctg aagtttaatc taagaaagag
     1801 taatattttg aaaacatgct tcatcgcata gaaatgaact taatttcaga aagaatacat
     1861 acatatcttt ttatatgttt tcagctgctg aatggttaaa aagcacaaat atccgaaaaa
     1921 aacatgaaga aatgtacttt ttttgttgta atgtgcatga aattctttaa gtaaactagt
     1981 taacataagt ttagtaagat tcctattctg tgaataatac gtatcagatt tatcttttat
     2041 tcttactaag aaaataacta ttaagggagt tgatttgaat aatggttagc aagaataata
     2101 agagagtatt tctagaaaaa acaaagaaac gagtattgaa gtacagtatc aaaaaattaa
     2161 gtgttggggt tgcatctgtt ttggttggtg ttggtcttgt cttgggaaca actgaactag
     2221 ttcaagcaca agatgaaatt tctccaagca ccccacttga aacagcgata agctccgtac
     2281 aagtaggtga caaagtagct tcggggaata cttttcagga gaatcctggt tatacgaaaa
     2341 attataactt ttcggattta caatttagtc ctcaagaact aactggagac acactaaaag
     2401 gcaatacaat tggatttgaa gtttacggaa aacataatat tgcagcatca actaaaaact
     2461 gggaaatccg tcttcaatta gatgaacgat tagctaaata tgtagaaaaa attcaggtcg
     2521 atccaaagaa aggaattgga tcttctagac ggacctttgt aagaattaat gattcgctgg
     2581 gtagacctac aaatatttgg aaggtcaatt atattcgtgc aagtgatgga ttatttgctg
     2641 gggctgaaac aactgataca caaactgctc ctaatggggt aattacgttt gaaaagagct
     2701 tagatgaaat ttttaaagag ataggcatag acaatctcaa gaccgatcgt ttaatgtatc
     2761 gaatctactt ggtaagtcat caagacgatg ataaaattgt accaggtatt gatagtacgg
     2821 gctacttttt aacagattca gatgatttct ataatagctt agatgtatct gaaaataatc
     2881 ctgaccagtt taaacatgga tcagtaagtg caaaatatga ggaacctaat actcaaacaa
     2941 aagatggttc aggatccaca ggtgctaatg gagctataat cttagatcat aagttaacga
     3001 aaaattataa tttctcatat tcagcttccg caaagggcac gccttggtat gctaattaca
     3061 aaattgatga acgattagtt ccatatgtag cgggtataca gatgcacatg gttcaggctg
     3121 acaaagtaac atatgatgtt tcttttgaat cagggaaaaa agtggctgat ttagcaattg
     3181 aacggcgcaa agatcatgaa aattatggtg taggttcaat tactgataat gatcttacca
     3241 aacttattga ttttgctaat gcaagtccac gtccagtcgt tattcgatat gttttacaat
     3301 tgactaagcc attagatgaa atcttagaag atatgaaagc aacagcacaa gttgaagaaa
     3361 ataaaccatt tggtgaagat ttcatctttg attcttggtt gtcggatacg aataaaaaat
     3421 taatccagaa cacttatgga acaggttatt attatttgca agatattgat ggtgatggaa
     3481 accctgacga taaagaagag agcggagaca cgaatccata tatcgggaaa cctgaattag
     3541 aagaagtata tgatgttgac acaacagtta aggggaaagt attcatccac gagttagcgg
     3601 gaacaggtca caaagcccaa cttgttgata aagaaggtac tgtattagca gaaaaaacta
     3661 tcgctccaaa tgaaaaagat ggggctccaa tttcagatac tgtagaattt gaatttacgg
     3721 gtgtagattc aagtaaatta atcgcgaaag atgaattaaa aatccaaatc gtttctccag
     3781 gttttgataa accagaagaa ggttcaaccg ttattaagga atcaccaaaa gcggttgata
     3841 aacaaaccgt ggtagttgga tttaaaccag atgctaaaga atcaattcgg aataataaaa
     3901 acttacctga agatgcagag tattcatgga aaacagagcc tgatacttct aacgttactg
     3961 atagtacgaa aggtattgta actgttaaga tcggaaatcg aactttcgac gtggatgtag
     4021 agtttgctgt aaaagcttct caagctatgg aaaatgatgc aacatacgta cctataacaa
     4081 caactccaga aacgacagtt caaagtggaa aacctacatt tgataaacca gatgttcctt
     4141 tagctaaaga tgccttttca attttagatg tctataataa ggacttcggt aatgcaagtg
     4201 ttgatgcaaa tactggtatt gttacattca ctccagctaa aggtgtagga gaatcggagc
     4261 cgattactgg aacaattcct attaaaattg tttaccaaga tggttctgta ggcacgaccg
     4321 atttagcagt aactgtaagt aaagatattt
//
LOCUS       DAMEEU010000129         4242 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.135, whole genome shotgun sequence.
ACCESSION   DAMEEU010000129 DAMEEU010000000
VERSION     DAMEEU010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4242)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4242)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4242
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.135"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..115)
                     /locus_tag="PB779_002759"
     CDS             complement(<1..115)
                     /locus_tag="PB779_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017370594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDE0740242.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDR"
     gene            246..698
                     /locus_tag="PB779_002760"
     CDS             246..698
                     /locus_tag="PB779_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740243.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            712..1401
                     /locus_tag="PB779_002761"
     CDS             712..1401
                     /locus_tag="PB779_002761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740244.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1526..3877
                     /locus_tag="PB779_002762"
     CDS             1526..3877
                     /locus_tag="PB779_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HDE0740245.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3957..>4242
                     /locus_tag="PB779_002763"
     CDS             3957..>4242
                     /locus_tag="PB779_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740246.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVES"
BASE COUNT         1459 a          557 c          854 g         1372 t
ORIGIN      
        1 cacgatcata taagatttct tgaacttcac gatagctaag gttataacga agatagtagc
       61 ccacggctac aataatcaca tcctgctgaa attgctttcc tttaaaatga ttcatcgtta
      121 ttcctcctgc tatctttttc tattattcta tcttatttga tagtagattt aaaactttgc
      181 aacagaacca attatcttat cgtagatata tattataaat ttaataagaa agcgaggtga
      241 gaatcgtgaa aaaaacgata ctaagtattt tttcagtatt tacaatatta attgggggct
      301 attttctttt gaatttagat tctgttaatt caaacgctca aataaaagat caaagagtag
      361 ctgaacataa taataaaaaa atgagtttga ccaaaaatat ctattctatg tcagatgaag
      421 aattgtataa agaatttggt gatttatccg gggaacagtt agaagaaagt attccaggaa
      481 ttagtgactc agataaaatt gttgtcttgt ctgctggtgg gcaattaatg ggagatggca
      541 aatccgaatt agttagttat aaacaaaatc acagacagtt tattgatgtt aatactgatt
      601 ccaacgctat ttcgattaag gatctaaaag agcttttaaa tagtaaaaga aatgaattaa
      661 agcagataaa agaaactaat tcagtggaat tagagtaaag gaagattcat tatgaaaaag
      721 atttttggtg tttctgttgg gctacttatg atgttaacat ttggaaatgc agtatatgct
      781 gctgagaaag aagttatttc agatccagag cagtacgcct cacgatactt tgctgatttt
      841 gaagaagaag ataaagtact tgcattgcca gaaggtggtt ttttaaaagg ggaagctaaa
      901 attgtatcta tggataatcc agatataatt caaggttcat ataattcaga aactgatcct
      961 gcttcagttt cagtgacaga agcaaaaaaa attgttgctg aaaaattcaa aaatgatatt
     1021 gaaactactc caattatgcc tcgaggagca tttccacccg atgttggtac tagcggacac
     1081 cttcttgtac tagcaggagg aggaagctat aaatcacagc catttagtgg tgcgggatgg
     1141 cgttttggag gtatgggtgt aaaaccagct gatggtacag gcaacttttt acgttggaaa
     1201 tcctacattg acgatggaag agtaggaaat gtaaatcaag ccaacgcaac taaatctggt
     1261 tctattcaag gaatggcatt gtatgctcgt gaaggattca aatactttgc accaaacggg
     1321 cctggttgga caatgaatat aggtatttat tacacttata atcctgttgc aggtacgtat
     1381 tatgttgttc aaaatattta ataaaacagc acaaagagat ttctttgtgc tgttttatta
     1441 tttttagttg ttgacaaaca ctaaaatata aaatataatc aacacataaa cgaacgtatg
     1501 ttcggcaaga aagcagggga tttttatgga tgagatggtt ttaagtactc agaaatggct
     1561 aaacaagaaa tacagtaatg ttacagggtt tgataaggtt ccagaaaatg ggcgaacagg
     1621 gtggcctaca atctatggac ttattgaagg actacaagta gaacttggta ttactaatct
     1681 agtagctaat tttggaccta ccactgaaaa aatgtacgat aatcaggtta ctcctaaatg
     1741 gggcaaaaat ctacctaaaa atattgtatt tcttattcaa ggtgcctttt ggtgtaaggg
     1801 gattaatcca ggtggcttcg atggggtata tactccatat ttagatactg ctgtaaaaga
     1861 gttgcagact gatgcagggt ttaatggaag cgctgtaact ggagttttgg atgcgaaatg
     1921 ggccaaagcg ttatttgata tgagtgcttt tgttcttgtt cccggcggag atagtaaaat
     1981 tagaaaaatg cagcaatggt taaatgtaaa ttatttagaa tacacgggaa taatgccttg
     2041 tgatggtatt tatcaaagaa attcaaatca agcattaatt tttgcattac aagctgaact
     2101 aggatattct cccagtgaag caacagggtc ttatggtaat gggacaacta gtaaaactta
     2161 tcctgtgtct gaaggtaact cgggaaacta tgtaagaata attcaatatg gattatatgt
     2221 taatggttat tttgaagacg gtacattcga tggtattttc actaaatata tgggtttaga
     2281 agtactggca ttccgaaaat ttatggtatt gcctgaatat actgaaatag cagatgttgt
     2341 tgtaataaaa ggactattgt ctagcgctgg agatattaga agatctgcag atggcgcaga
     2401 tacttctacg caattaacta gatctcaaat ccaaacattg gttgataatg atataaaaat
     2461 agttggtaga tatcttactg gtactgttgg aattggaaaa gatgaacgaa ataagtatct
     2521 aactacagag gaattgaata atattttttc taaaaattta tctgtgtttc ctatctatca
     2581 agatggaggt gcagcattag cttattttac ttatgatcgt ggcttatcag atggtaagaa
     2641 ggctatagat gcagcaaaaa atctaaatat accattaaca acagttattt attttgctgt
     2701 tgatctagac atgttagggg aagaaattct tgcatatgct ggagaatatt ttaagggggt
     2761 atctgctgta atgtcatata gcgggtatca aacgggtgtt tacggaacaa gaaatgtttg
     2821 ttctcaaata atcaataacg ggtatgcttc gtttgcattt gtttcagata tgtcgactgg
     2881 ttatagtggg aatttaggtt ttcctatgcc tagacaatgg tcttttgatc aatttgttga
     2941 atttaccata ggaagtggca acggagctgt tggtatcgat ttaatcgcta catcgggtag
     3001 agatagcgga tttaatgagt tatcaaatga tactaataat gataattaca ttgccaaata
     3061 caatcagaag gttataaatc agatggtacg tgcgtatcaa tatctatcac aagctggtct
     3121 tgataatcct tggaaccctc atttgacatt ttatagatat gtaaattatt ctggtttgtc
     3181 atgggacatc atttcttctc ctgtaacaga gcatgataga aaaatttatg atgaatatag
     3241 gaataaatta actaatagcg agggcctgta taattatttt atagatccta atactggttc
     3301 aataataggt ttgcctcact taattgtgac gttacaatca cagatgtttc tagccgacac
     3361 aatcaatgat agtgtttctg actttgcagg ttggttagga gatttaatga cttgctgggg
     3421 tgaagttaag aaattaggaa tacaaatgga gcaaggtgta tttgcattag taggtacggc
     3481 tgcaggtgga acatttagtc tagaagattt ataccaagat gttgacgcgg taaatgttta
     3541 taccttagca aaaagaaatt ctgattcaac agctttatcg gctttaaaaa cgtactattg
     3601 tgataagggt gctattgata gatttaatca atttgttaag aacagatttg gttcttcaga
     3661 taaaatcgct tcagtaacaa atagtttatt agaaaatgac gaaacagttg atatcttagg
     3721 tgtagggata atttcatttt tcattgataa aatagttaat aattcacttg ggacagattt
     3781 tacttatctt gattttattg gagatgaggg gaaagttgca aatggatttt ctgaaaaaat
     3841 tattcaattt caagaaaata gaagtaaact taattaagaa tcgtttacta tttaaacagt
     3901 gtccttttcc tttttaaata tatacgataa aataagtata tgaattgtaa aaggacatga
     3961 tgattatgga agaaatagaa tggaataatc tgactcaaaa taataaaaat aattctggat
     4021 gtggaattat ctttatgttt gttatagttt tgggaatagt agtactttta ataactgtca
     4081 agatagtaga ttactttgcg aatactcctg aagaacaaat acagagaaaa cttcctgagt
     4141 ttgaaagagt accaccttat gatccaagag ataattcatt tcaagtaaaa aaattaaaag
     4201 agtctccaaa tgaaatgtgg tttgaagtta cagttgaatc aa
//
LOCUS       DAMEEU010000130         4158 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.136, whole genome shotgun sequence.
ACCESSION   DAMEEU010000130 DAMEEU010000000
VERSION     DAMEEU010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4158)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4158)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4158
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.136"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            180..776
                     /locus_tag="PB779_002764"
     CDS             180..776
                     /locus_tag="PB779_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HDE0740247.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            900..2699
                     /locus_tag="PB779_002765"
     CDS             900..2699
                     /locus_tag="PB779_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HDE0740248.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2977..3189)
                     /locus_tag="PB779_002766"
     CDS             complement(2977..3189)
                     /locus_tag="PB779_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740249.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3651..3800
                     /locus_tag="PB779_002767"
     CDS             3651..3800
                     /locus_tag="PB779_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740250.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4053..>4158)
                     /locus_tag="PB779_002768"
     CDS             complement(4053..>4158)
                     /locus_tag="PB779_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDE0740251.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          706 c          729 g         1495 t
ORIGIN      
        1 ttttaaaaaa aacaagttat taaataagtc tttagttgga tgtttttttg agatcaatct
       61 tttatactta tgatgaactt acaaaattgt ttgttttctg tcatatcaaa aaatggcgca
      121 gttagttgct tttctagtaa agtatagtta acaaagaacc tctaaggagt tgatgaataa
      181 tgaatattgc tgcctctcga aaactgataa atttcatatc cattatcgga ttaggcctat
      241 caatcgcgct gacgatttat tttattaatt taggtgtttt caaagatttg aatgcgttaa
      301 gaggattagt aggtgattcc atcattttag gaccgattat ttttgtcttc atccaaatcc
      361 tgcaagtagt tattccaatc attcctggag ggatcagtac tgcagctggt gtcctgatat
      421 ttggccctta tgctggattt atctataact atattggaat ctgcattggt tcgattatca
      481 tttttctgct agggcgtcgt tatggaaagc cattcatact ttccatgatt agcgataaga
      541 catataacaa atatattggc tggctggata atcaaaaccg ttttgagaag ctgtttgctc
      601 tagctatttt tcttccagtt gctcctgacg atgcgttatg tttgatggct ggattgacaa
      661 acatgtcagt gaaacgatat acactaatca ttttgattgc taaaccactg tcgattttct
      721 tatatagtat ggccttgatt tatggaggtc aatatctaag tggtcttctt ggataatatt
      781 tattttgtaa aattagtcat tgattgacaa tgttaaatct gggaaagggt ctgcaaaaca
      841 cactgcaccc tttccttttt cattagattt gcgctataat gtgaagagca ggtgatagga
      901 tgaattattt gaaacgtagc ttaggtaatg cttgggactt tttaaaagga acacaagctt
      961 atttccgtga tgtcttgctg atgcatggct ttattttatt tatttgttta cccttattga
     1021 gcagtacgac ccgttttatt ttacaccgag gggcaattga ctatttgtct tatgacaata
     1081 ttccttcaat tttttctcaa catcctgggg ttctactctc gttaatcgta gttttgatga
     1141 cgattttact gttagtttat ttcgaattta cttttctttt gatgagtgtt ttttttatta
     1201 aaaagaaaga accaatctct ttgaagcaac tcttacactt gacgatactt cagctgaaga
     1261 aagtgagacc cattactttt ttgtttttcc ttgcttattt tttattgatt ctaccgatca
     1321 gcggattaag ttttaattct gatctactgt caaaaataaa aatccccgct ttcattatgg
     1381 attttatttt tgctaatcgt tggatcatcg tcagttcctt tttactcgtt tatattttcc
     1441 ttggctatat tgggattcga ctgatttttg ctttaccgga aatgattcta cgggatcgtc
     1501 cttttcgagc agccattcgg gaaagctggt cattgaccaa atcgcgtctt ttggccatca
     1561 cgggccaatt tattgtgatt ggcggtacga ttttactcct ttcttcttta ggatatatcg
     1621 ttgttatttt ggcacaaagt atggttgaac aatttttccc agactatgca ttgatcagcg
     1681 ctgtgtttgc tatgacgctt ttacaaggga ttttattatt caatatcgtg atgtctaccg
     1741 tagggatttt ttatatcatt gttgatttca tggatgacga aggcttcttg cctgagatcc
     1801 ctaagtggtt tatcccacaa gcccccaact tgcgtttctc tgcgctgaaa aacactggtt
     1861 tgactctttt tgcagttttt ttcggtattg gcgtctgtct ttacaatatg gattatctga
     1921 cttcagctgt tcagacaaaa ccagtgactg tctctcacag aggtgtgagt acccaaaatg
     1981 gggcgcaaaa tactttagaa gcacttgaaa aaacaagcag agactatcat cctgattatg
     2041 tagagatgga tgttcaggaa acaaaagatg gtcatttcgt agtgatgcat gatgcaaatc
     2101 ttcgtcactt aacaggggta aatggaacac cacaggatct tacattgaaa gaattgacaa
     2161 atcttacagt tactgaaaac ggagtgcaag cccctgtttg ttcttttgat tcttatttgg
     2221 aaaaagcaca taagctaaac caaaaattac ttattgagat caagacctct aaaaaagatt
     2281 cggatgacct tgtcgaacga tttgtccata aataccgcaa agttatctta gagaaccatc
     2341 atattttgca aagtttgacg taccaaaccg tttcagattt aaaagaagca gaaccaaact
     2401 tttatgtggg ctacatctta cctttcaata ttgttgggcc ccctgtgacg cctgctgatt
     2461 ttctgacaat ggaatatagt acgatcaacc gtaacttcat taattctgcc caccaagacg
     2521 gaaaagaagt atatgtatgg acaatcaacg attcagatgc tatgagtcgc atgatgtttt
     2581 atggtgtgga tggtatcata accgatgaga tgggactact aaatgaaagt gtgaaacaaa
     2641 cagatgaaga aatcacttat tcagataaac tgctaaattt tgttttggga gtcggctaat
     2701 caaaaatcgt taatgaaaaa agtctttata caacaaaaaa cgcataacct gccaccgcag
     2761 gtatatgcgt tttttgtttg acgctcataa tgtgtgctta actttctctt gattccttca
     2821 tcgcacgaac aatagctaaa atagcaggaa ttgcagagat cactgcaaga ataattccca
     2881 ttttccctga actttttctt tttggcatat cttctcgctc ccttctgtct ttatttatat
     2941 tataagggag ttcttgcgaa ttctcaaaaa tactgtttaa gaaaccaatt cagcaggtgc
     3001 gctaatatca cagaatttta cgagcatgcg atacttgctt tcattgataa gttgatagtc
     3061 tcgttggtca taactttcaa catacacgac agccgtgttg atatatgtac gttcaataca
     3121 gccgattagt tcatgagata ctccgatcgg tttgcatata taagatcttc ctacttctgc
     3181 ttttaccatt tcattccctc ttttctttat ttttattttg ttttttcttt attttataat
     3241 aacaaattac cttgtatttg aaaacgtttt tatccatttt tttatttttt attttgagta
     3301 tctttctgct ttttagataa ctatttttta acacgatctt agacgttgtg acaaaaacgt
     3361 ttgtttatat tcctatgttg ttcgtgcgtt tttttcttta tattgctaag ttatttataa
     3421 agaggtgagc atatgattta tattcaagca atagtatttg taaccttgat gattgggcta
     3481 cttatcggat taaaagaaaa tagctaaacc atttaagaaa aaataaataa ggaaaatgat
     3541 aaatgctttt taattgcatc aaaaaacgta cgatgctaaa cttggtataa gttcgaaagt
     3601 ttaaaggaaa ctttcaagaa ctaaattaca ttacaaagga gatgaatttt atgacgttta
     3661 caaaaacaaa tatgcaatac cgcgtagctt ttgatacaac ttctaaccgt tttatggcga
     3721 ttgatgcaca aaacgaaaat aacgttgcgt ttggtattac aatcgaacaa gcagtccgag
     3781 cattaaacga atctagataa ggagtgaacc attccaaatg gcgactgatg agatctcgga
     3841 aaatcaataa aagacgtttg taacggtaat ccgcgacaaa cgtctttttg tattcattac
     3901 atatatttgg aaattgtctc tctttatctc tagacctaaa caaaaacaca agttctaata
     3961 tcaaccatct cgttttttat gacaattttg ttagctgttt cgatgataat attccgttat
     4021 tatctgtata atatttaata taatcttaat tgtcaaatta agttagacag atcatcaata
     4081 cttacgtaac tcaaaaatac ttccaaaggt gttcgataat ccagtgattt tctaggaata
     4141 ttatttcgtt tagatgcg
//
LOCUS       DAMEEU010000131         4070 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.137, whole genome shotgun sequence.
ACCESSION   DAMEEU010000131 DAMEEU010000000
VERSION     DAMEEU010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4070
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.137"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            86..1435
                     /locus_tag="PB779_002769"
     CDS             86..1435
                     /locus_tag="PB779_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HDE0740252.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(1563..2153)
                     /locus_tag="PB779_002770"
     CDS             complement(1563..2153)
                     /locus_tag="PB779_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HDE0740253.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVLVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            2300..3652
                     /gene="brnQ"
                     /locus_tag="PB779_002771"
     CDS             2300..3652
                     /gene="brnQ"
                     /locus_tag="PB779_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HDE0740254.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         1176 a          744 c          789 g         1361 t
ORIGIN      
        1 aaaattttgg aatcttagtt gtgtttttca gaaaactctc ttaatatgga agtaattaaa
       61 cttttttagt taggatgatt taaaaatgaa tgaagagcaa gaactgcagc gtggactgaa
      121 aaatagacat gtccaactga tttctattgg cggagcgatt ggaacggggt tgtttttagg
      181 ttccggaaag tctatccagc tagctggccc ttcgatattg ctcgcctatc ttattactgg
      241 atgcatctgt tttttcatta tgcgtgcgtt aggcgaactt ctgttatcaa acaccaataa
      301 ccattctttt ctggattttg ttgcagaata tcttggcaaa aaagcggctt tcatcactgg
      361 ctggacgtat tggttctgct gggtatcgat tgcaatggcc gatttaacag ccatcggaat
      421 gtatgtacgc tactgggcgc ctggtgttcc tcagtggctt cctgaactga ttgcattagg
      481 tcttcttctt tgcttgaata tggtggctgt ctcattgttt ggtgagttag agttttggtt
      541 tgcattgatc aaagttgtag cgatcattgc ctttatcctc gtaggagctt atatgatcct
      601 cacccactat acgacagata ttggcacagc cagtatcacg aatctatggt ctcatggcgg
      661 attctttcca actggtgcaa aaggatttat cttagctttc caaatggtaa cctttgcttt
      721 tgctgggata gaattagttg gattagtcgc tggagaaaca gaaaatcctg aaaaagtgtt
      781 gccggaagct atcaataata ttcctatcag gatcatctta ttttacttag gatctctttt
      841 tgtcattatg gcaatctatc catggaacag cttgaatcca gataacagtc catttgtaga
      901 agtattttcg gaaattggga tcacgattgc tgcttccttg atcaatttag tcgtattaag
      961 tgcagcagct tctgcctgca acagtgcaat atatagtaca ggacgtatgc ttcgttcttt
     1021 agcgcaagaa ggcagtgccc ctaaaaaatt caaaaagtta acaacacatc atgtgccagg
     1081 gaatgctttg acattttcta ctatcgtcat tttcatttct gttatcttga attacgtgat
     1141 gcctagtgaa gtattcacac tagtaagcag tattgccact acttgtttct tgtttatctg
     1201 gagtatgctt gtctacacgc acatgaaata tcgtaaaagt atcctcggca aaaaagctca
     1261 ttcatttaaa atgccgttgt acccatttag taattatctg gtatttcttt acatggcctt
     1321 tgtgtgtgtc gtcttgttcc taggaaaaga tacgagaatc gctttattac taacacctgt
     1381 gtggttcttg cttctattac taatctatca tatgaaatat gaacgtaaga agtaagaaag
     1441 tagttgtgac agaagtggtc agcttcgaga aataagaagg aatttacgaa aattgcttct
     1501 taaatttttg tgaaatttcg gcttatttct tggagataaa agcttctgtc ccagcctctt
     1561 ttctatttcc ccggaaacaa ccgctgataa taggcatctg cttttttata ggaaaaaatc
     1621 caaataccag atacaaaaaa acgtccgaat aacccgatca acggtacaaa aaagacaccg
     1681 gcaatcaagc ataagttaat catcatggag ataagacttc gacggtcctt tgacaaaact
     1741 ctcacgacat gggaatctgg tttatttgct ttcatgattt gcctcatcaa gataccaaaa
     1801 gaaaaactcc acatcgtgta tactaagaca taagccatct caggccaaaa agcttcaggg
     1861 ttacgcccga cccaactagt aacagaagga cataaagtca gccaaaagag caaaaagata
     1921 ttcgaccaga ccactcggta attaattcgt tctgccatct gaaatatacg atgatggttc
     1981 acccagatca ccgcaacaaa tataaagctg atggtataag ctaataatgt atttcggatg
     2041 acccataaag aatgaaagct agatgtatta gggatcttga tctctaatac aagaactctc
     2101 aaaacaatgg ctaccactcc atcagtaaat gcttctaatc tcgactttgt cacgatgatt
     2161 cctcctcaga tgattcagcg cttttatttt atcacttacg ttattaaata accatcgttt
     2221 tatataggga attttctgaa aattgttgca tatttttcga aattttgtta cttttaaaaa
     2281 aaccgtaaag gagttatgta tgacaaaaaa attatcattt aaagactatc tttttatagg
     2341 ctccatgctt ttcggtctat tttttggtgc tggaaatctt atctttcccg ttcatttggg
     2401 tcaagaagca ggcgctgcta ccttttgggc gaatctaggt ttcttggtta ccggtatcgg
     2461 tcttcccttc ttaggggtga ttgccattgg tgtatcgaaa agctcaggtg tatatgaatt
     2521 agcaaaacgg ataaatcaaa catatgcgat ggtttttacc atcttgcttt acttagttat
     2581 cggaccgttt tttgctttac ctcgccttgc aaccacatct ttcgagattg gtttagcacc
     2641 atttatcgat cctagcagac agacgctata tctagcaatt ttcagtattg tattttttgt
     2701 gctggcttgg tggttttcaa gaaaaccgac aaagatatta gattatgttg gaaagttcct
     2761 gaatcctgca tttttggttt tattaggtgc tttgcttctc cttgcttttt tgaatccact
     2821 aggttctgta aatcaagcgc ctattcagcc aaattatcaa gagcatgctt ttttcacagg
     2881 gtttactcaa ggatataaca cattagatgc gcttgctgct ttagcatttg ggatcatcat
     2941 tgtcacaaca atccaaaaca tgggtgtaac aaaacctgct gaaatcgcta aagacacgat
     3001 caaatctggt gcgatcagca ttatattgat gggaatcatt tatactttgc tcgcttattt
     3061 aggtgctatg agcttaggta gctttgctct aagtgaaaat ggcgggatca cgctggctca
     3121 gattgctgat cattatttag gtacttatgg cagtatctta ttagcattta tcgttatatt
     3181 agcttgcttg aagaccggta ttggtttgat tacagctttt gcagaaacat tcacagattt
     3241 gtttccgcaa agaaattacg cattctttgt tgcacttgct agtatccttc cttgtttagc
     3301 ggcaaacgta ggcttgacga atatcattca attttcgttg cctgttttga tgttcatcta
     3361 tccattagca atgacactga ttttactagt gttagttggt cctttgttta agcagcgtac
     3421 ggctgtttat cgaatgacta cttattttac attgattgct tcgatttttg atgggttgaa
     3481 cgcttgccca gaaactatca aacaaacacc tattgttcaa aatcttttat atgttgcgga
     3541 aagctacttg ccgtttttca aattggggat ggggtggatc gtaccagcag ttatcggttt
     3601 tgttatcgga ctgatttgga gtttcgctaa gaaagaagaa gtagcagatt gataaaagag
     3661 gttgtgaaag agacgttcag ccttgagcaa taaaaagtaa ttttgaaaaa tggcttctca
     3721 catttttgca taaatttgac ttaataccga gaaactgact tttgaacacc gtttattgag
     3781 aggtcgtgaa aaagccgctt agtttcaagt attaagaaat attttgtgaa aatggcttct
     3841 cacatttttg cataaatttg acttaatacc gagaaactgg cttttgaaca ccgtttattg
     3901 agcgtctata aactgacctg agtattagag aaacaaaacg gcaaagtagc tccatatact
     3961 ttgccgtttt gttttgaact aataccgaag agaagctgat caaacaacat ttcttttata
     4021 atatagattt tagacatata tatgatataa aaatagtttt cgcaaaaaaa
//
LOCUS       DAMEEU010000132         4055 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.138, whole genome shotgun sequence.
ACCESSION   DAMEEU010000132 DAMEEU010000000
VERSION     DAMEEU010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.138"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(165..1670)
                     /locus_tag="PB779_002772"
     CDS             complement(165..1670)
                     /locus_tag="PB779_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0740255.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(1667..2353)
                     /locus_tag="PB779_002773"
     CDS             complement(1667..2353)
                     /locus_tag="PB779_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0740256.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2546..3967)
                     /gene="gndA"
                     /locus_tag="PB779_002774"
     CDS             complement(2546..3967)
                     /gene="gndA"
                     /locus_tag="PB779_002774"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HDE0740257.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1115 a          857 c          693 g         1390 t
ORIGIN      
        1 tgttttttcg ttcatctaaa agatacttac atttaattaa cggatgttat tctatttaat
       61 tgttcgctag tttttttata atgacatccc tgaatttctc acttgcttgt attttgtacc
      121 ttattctttg ttggatatat aaaaaaacaa gtaaagcaca tgctttactt gtcttctgcc
      181 tttgcgatag gaataaagat tctaaaaatt gtcccttgcc ctactacact ttctgctaag
      241 atacgtcctt tatagttttc aaccagttgt ttagcgatag acaaccccag accatttcca
      301 cccttcgttc tagctcttgc tttatccact cgataaaaac gattgaagat cttattaagg
      361 tcttctttgg gtattccttc gccaaagtcc tgaatcgcga tctcaaattc attcagagtg
      421 gaagaaatag agatatggac ttcttttcgt gtagttgaat actttactgc gttatccaat
      481 atgataatga ttaattgttc aaagtgatta cgataaattt gcagggtcac ttcttttgtc
      541 aaatcatcat ctaaagtgat cacatagtct ggatataata tcttgaaatt attataaact
      601 tgataggtga cttcttttcc tttagttgtt tcattcgcat aatgaacatc tacttgttct
      661 gctcttgata agtctagcat ctcttgaact aagcttttca tacggctgat ttcttgcatg
      721 ctggcgctta atgattcttc taatatctca ggatcatctt tcccccaacg atttagcaga
      781 ctaagatgcc cttcaataat tgcaacaggt gtccttaact catgagatac gtcttccacg
      841 aattgctctt gttgttcaat atacaaacgc atacggtcaa gcatctcatt gaatatttca
      901 gctaaatctg ccaattcatc atttgtgtcg atttcaggca tgtggatatc tgattgcgga
      961 tctttacgta tagtatccat tgtatctctg agtaccttga gtggttttaa gaaataagaa
     1021 gataaaaaga aacctaaaat actacttaag atcaaagaaa caacttctaa aacaataaga
     1081 gtcaataata gcttatttcg aatatcatag aaagaagata attcatagaa gctttgcgca
     1141 tagccgatct tttctcttgt acctttagaa tatataggct ggatagataa aaagccagtt
     1201 tttccttcta gtgtaacgat cgttggaact ttacgtgtag tctgaatcag gtttcgactg
     1261 ttttcatggg ttttaaaaat caagttctcg tccaaatcat aaacataaag atccattgat
     1321 ggctgcccta gctcagctat aaaggaatcg atcttcatta agtttccttc gaccagtgaa
     1381 gtatgatcta cgacctcatc tccgtcattt gtcgctttcg tcagattacg atacgtattt
     1441 actaatgtca gttcttcatc cgagttagcc aaacgagaag ctacttctga aatcgtacgc
     1501 tctacattgt ttctttcttt tgccacaatc agattgatag atgatttata ggtaatgaca
     1561 gcgaaaattg taaacacaac gaatatgaag aaagaactcg caaaggccca cttgattgtc
     1621 aaggagggcc ctttcagttc tcttttttcc gattttttcg gctttatcac gagcgcatca
     1681 cataacctgt tccgcgtaca gtttggatat agctttcctc cccgggaacg tcaattttgt
     1741 tgcgaagata acgaatatat acgtccacta cgtttgtttc aacttctgtt tcgtatcccc
     1801 acactttatt tagtaaaacg tcacgtgcta ataccacgtt cacgttttcc attaaagtaa
     1861 gcagcaactc gtattctctt tttgttagtt caattacttc atttccgcga cgtacgacac
     1921 ggttttcttt ttcgatagtc aaatcgcgat aagtaatagt agtttgttta gccacatttt
     1981 tatcgccttc aatatcgatt cgacgcaaca atgcacgaag acgtgctaat aattcttcga
     2041 tagcaaatgg tttgacgatg tagtcatctg ctccgtggtc aagtccagat acacgatcga
     2101 tcacagaatc tcttgcagtc atcataatga ttggtgtatt tttgacttgg cgtacacgtc
     2161 tgcagacttc taaaccgttc aattctggga gcatcagatc caacaatatg gcatcccact
     2221 cattatttaa tgccgcatct aaaccagttc ggccgttgta gtggacttct gcgttatacc
     2281 cttcatgctt caactctagc tcgacaaatc gtgccaagtt cttttcatct tcaatgatta
     2341 gaatattgct catttattat tttatccttt ctattctact ggctttttaa aaactctatc
     2401 attataccga taatatgctt aaaaatctat agtcatttta tcatggatag caattttaaa
     2461 aaagagctga agtctactca taacaatcga cttcagctct ttcgtcctct ttttattttc
     2521 tcatttccta acagccgaaa gactattatt cttcatggta ccatgagtaa tggaagattc
     2581 cttctttgtc gacacgctca taggtatgtg cgccaaagta atcgcgttgg gcttggatta
     2641 tatttgcagg cagacgttct gctctgtatg aatcgaagta agcgatggct gatgagaaag
     2701 tcggtacagg tacgccagct tggacagcca aggcaacgac gtctctgact gattgctgat
     2761 attttttcgt gatttcaacg aagtaatcat ctagcaataa attttcgatc tcaggatttt
     2821 tgtcataggc atccgtaatt ttttgcaaga atcgagctcg gatgatacat ccagcgcgcc
     2881 agatttttgc gatttcacca aatggcaagt cccaatcaaa ttcttttgaa gcgacacgta
     2941 attgagcaaa tccttgggca taactcatga ttttactgaa atacaacgct tctcggattt
     3001 tttcgaccaa ttcttttttg tctcccgtga actcaaaatc gttcgtacga gacaaaatct
     3061 tgcttgcttg tacgcgttct tctttataag cagaaatata gcgggcaaat acagattcag
     3121 tgatcaatgg aagtggcaca cctaagtcaa gcgcgctttg gcttgtccat ttacctgttc
     3181 ctttattccc agctgcatca aggatcacat ctactactgg tttacctgtt ccttcatcgt
     3241 ctttacgtgt cagaatgtca gcagtgattt ctatcaaata gctgtctaat tcgccttgat
     3301 tccattcttt aaagatatca gccatttctt ctactgaaag gtttaaaata ttcttcatta
     3361 agtcataaga ttcagcaatc agttgcatat ctccatactc aataccgttg tgtaccattt
     3421 tcacataatg tccggctcca tttgggccaa tatatgtgac acatggtgct ccgtcttctg
     3481 cttttgcaga aatttgctct aagattggtg caactagcgc ataggcttct ttttgtccac
     3541 caggcatgat tgaaggtcct tttaaagctc cttcttcacc accggaaacg cctgtaccga
     3601 taaagttgat gccagagttg gctaactctt cattacgacg catcgtatct ttaaagaatg
     3661 tatttcctcc gtcaatcaaa atatcgcctt tatcaaggtg aggaagtaac tcttggattg
     3721 ttgcatctgt tgccggtcct gctttgacca ttagcaagat ccgacgtggt ttctcgatag
     3781 attctacaaa ttcttcgatt gtatatgttg ctttgaaatt tttatctggg tgttcttcta
     3841 ctacagcggt tgttttagcc cctgtacgat tgaataaagc cactgaatag ccgcggcttt
     3901 ctatgttcaa ggctagattt ttacccataa cggccatacc gacaacgccg atttgttgtt
     3961 ttgacatatg aactcctcct acatacggga tttctcccta atctcttaca ttatagctta
     4021 acacggctac attgcaaact aaagaacaac atatt
//
LOCUS       DAMEEU010000133         4035 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.139, whole genome shotgun sequence.
ACCESSION   DAMEEU010000133 DAMEEU010000000
VERSION     DAMEEU010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4035
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.139"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(6..548)
                     /locus_tag="PB779_002775"
     CDS             complement(6..548)
                     /locus_tag="PB779_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HDE0740258.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            683..1072
                     /locus_tag="PB779_002776"
     CDS             683..1072
                     /locus_tag="PB779_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740259.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            1076..1840
                     /locus_tag="PB779_002777"
     CDS             1076..1840
                     /locus_tag="PB779_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HDE0740260.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQADEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            1969..2916
                     /locus_tag="PB779_002778"
     CDS             1969..2916
                     /locus_tag="PB779_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HDE0740261.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            3046..3786
                     /locus_tag="PB779_002779"
     CDS             3046..3786
                     /locus_tag="PB779_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740262.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
BASE COUNT         1341 a          686 c          814 g         1194 t
ORIGIN      
        1 gtgagttatt ttccttgtcg ttttctcact tttttagtcc agaaaccacc tgaaatatat
       61 tttggctcat aagaaatgat aaaagcacgc tcttcgattt ctttgatcag gcgatacagt
      121 tcacgttcgc tttttctagg agaaagtatt tcgagaacta gccgctcacc ttccagcccc
      181 attgcagaag tctgtgtcac accataaccg tgttctctca gtatacccgg caaactttta
      241 tcttctgcgc tatttgctgg caaaatcgtt gtgaccatga tgtatcctaa tgccaatttg
      301 tcttcaatca aaattccgac actgatacct actgcgtaac ctaacgcata gacaaataaa
      361 ttcagtggat tatctaaacg atctaaaaca agggataagc cgacgatata aatcgtgatc
      421 tcgaccatac tgacaagtgg agcaatcagt cgatagcctt tcattgtcaa catgaaacgt
      481 aacgtgttca gagtgatata agcaaaatta atgaggaaga tcatccccaa catttttgga
      541 tcaatcattt gtaaaactcc tttcatttat ataacaacaa tatcaaaaaa aatcgtaagt
      601 gaagaaaaat tgaaacttta tacatacaaa aaaatgataa aatgattata atagaattat
      661 aaagataggt taggtgatta aaatgaaaac ggtcaatcgt gtgttttgtg ccagccacgt
      721 gctaagtctc cttctcagta tatacttagg tgtctattcg attcaacagc caattgaggt
      781 agagaacatt gtttttcaga tgtcgctgac agatggttta attttaagcg tttttttctt
      841 tttgatactg tttattggta atattttcgg tagcgttgcc agttttttga atttttctat
      901 ttatccactc ctttcgctag cattaggagt ggtgggactt tgttctctgt gcttatttcc
      961 cgagccattc agtcctgcat ttatattatt tggtacactg aacctgttcc agacaactgt
     1021 tggagcatgg ttgctatggc gatcaggaaa tttaatgaaa ataggtgagt aacaattgaa
     1081 tccaattata ttgaaacgtt ctgtccatca tattccagtg ttagaagttg ttctgaaaga
     1141 attaagagag gaacgtattc ccgttgtcat ctattatcac ggatggcaga caagtaagga
     1201 gttagttttg acgcaaggaa gaaaaattgc gcagcagggc attcgtgtga tcctgccaga
     1261 tgcgatgaat catggggagc gcaaacagcc ggtttcttct attccatcct atacattttg
     1321 ggatagtatc tacggaaatc tgtttgaatt tgacacactt atcaagcatt tagaaaaaag
     1381 aggtcttcta catgatcagc ttgcagttgg cggggtttcg atggggggaa tgacaacatg
     1441 cgccttgttg gctaaacatc ctcatatagt agcgggcgtg tgtttgatgg gttcccctgc
     1501 acctttggaa tatggaaaag aaatcgtaag gcgcgcatcg gaatataatt atgtcgtacc
     1561 aaaagactat tttgatttga tttcatgggt taagagctat gatttgtcat tgcagccgga
     1621 aaagttagct ggacgtcctc tgttcttttg gcatggacaa gctgacgaaa aaatccctta
     1681 tatacaaacg gaacgatttg tagaaaaaaa tcggcataag tcttacggaa aagaaattgt
     1741 ttttcgttcc tcaaaaacac agcgacatat ggtacaaata ccactaatgg aagaagcttc
     1801 cactttttta gcaaaaaatt tgataaaaaa gtataaataa ttgaaacgga aaatcactca
     1861 tgacgataga ggattttccg ttttttattt tgggctataa taaactctgt taggaaaatt
     1921 tggtataatt gatagtaaga atgacaacat gttagaaagg aagagagcat gcccacttta
     1981 gcagatgttg caaaacgtgc caatgtttca aaaatgacgg tctctcgagt catcaatcat
     2041 ccggaacagg tgactgacga attgaaagag ttagttttct cagcaatggc tgaactggat
     2101 taccgtccaa atattgctgc aaaagcactt gtcacgaatc ggtcgcagat catcaaatta
     2161 tttatactgg aagaaatcga cacaactgag ccctattaca tgaatttgct gatgggaatc
     2221 gctaaacgga tcggtaaagc gcattattct ctccaattag ttacaaatga tgccttcgac
     2281 gtcggttctt gtgatggata catcatcaca ggtgtcagaa aaaaagactt cgattggatc
     2341 gaccgtttgg aaaaaccagt tgtcttgttt ggggaaaatt ctgaaggata tgattatgta
     2401 gacagcgata atgaatatgg tacagcaaaa gcaacgcaat atgccttaga aagagattat
     2461 caaacgatta tttatatcgg tatcgaagtg gacgagcctt ttgaaatttc aagggaaact
     2521 ggttatttat ctgtgatgaa ggaagttgat cttcctagta aaatcttgcg gtttccaaat
     2581 cattcgacag aagtagaaag atatatgaca gaaaactggg cagattttac agataaaact
     2641 tgttttgtat gtagttcaga tcggctagca ctaggagcag taagagggat tataaatgct
     2701 ggaggacact tgcccgaaga atttggtgtg attggatttg atggggtatt tttagaccaa
     2761 atcagttcac ctaaattgac aacgatcaag caagatatta tacgtatggg tgaagtatgt
     2821 ggagaaatgt tgttaaaaaa aatagaagaa aaaggggcga gtcaaggtta tcgtcgtttt
     2881 tttcctgaac tagttatcag agagacaacg aattaagtct tattactata tatatattta
     2941 tgaaattcat cgctattttc ttaaaataat cagcgcattg ctactgaaaa caatgaatct
     3001 gtgctattat tgagaaaagt tccatttttg agaaggatgg tttgaatgaa agaaatcaga
     3061 cgaaaacatt tccgttttcc tgcgtacgat gatgagttag gcgtaaaatt aaccaacgac
     3121 aagaagcgag tattatttga cggacaagaa gatcttttga ctgaacagaa tcagtccccg
     3181 tttgaacaga tgaaagaatt tcatttcacg aacacgaaca ccgagaaaat ccgtcgcaag
     3241 cgtcgtgcaa caaatggatt gaagtcagct ccgcgtaagg aaaatttgga aaagcataaa
     3301 ggaaaattac cggattatac cggccattac caatcagaaa tcacatcgac aggacgaaaa
     3361 aaactttttg gtgattcctc tcgttctgtc agacaaagtg aaacaaggac agagtccaag
     3421 catactacac gaaacgcatc tgttgacacg aaggtgcggg agcgttctta ttttgttcct
     3481 aaatatgtac ccgcatcgat tatcccagac cctagagaaa gcaaaatttc tgaggatcat
     3541 ttaatcgaat cgatgaaaaa aacggatgac tcttatctgt tgttcgatac agaaccgacg
     3601 ccgtatcaag aaaaaagaaa tggtgagccg tctgtacgaa cattcaatcg aacaaaaacg
     3661 ttagaggaaa caaagcagtc agaagaaaaa aaatcgaaaa aaagccatgg tatcttagaa
     3721 cgctcattac aaggattgat cgatgatcaa ggaaactctt tgggagaaaa tagctatttt
     3781 aaataagtga tatacaaatt tatattcggc tacagttgga aaggaaacgc tgcggcgttt
     3841 ccttatttta tactctatcc gaaagtttat atcgtatcct caaatttttt tgagtttaag
     3901 cgaatttttt ctcccaataa gtaagaaaat aatggcaaaa taaaaaaaca aactattttc
     3961 gcagatcgtt tgcaaaaata gtttattttt ttataaagaa gattttactg aataatatca
     4021 ttttagttta cataa
//
LOCUS       DAMEEU010000134         3820 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.140, whole genome shotgun sequence.
ACCESSION   DAMEEU010000134 DAMEEU010000000
VERSION     DAMEEU010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3820
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.140"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            169..771
                     /locus_tag="PB779_002780"
     CDS             169..771
                     /locus_tag="PB779_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740263.1"
                     /translation="MEDIILRDRLTDPLKNSLANVIYDILREADKVYSNYNGKVSWVI
                     YSFLIKEFFKEQINNSYELGYHFTVYYEDIIKRLEDLEWYAYYDLLEVFASAKILDKK
                     KREEVNKILESENSGYRLSESNEFIPITDDISIKSINAVSESPFNYAKNHIHKSLTYI
                     SEKENQDYNTVVREAISAVESCLIEFSGLPANKKILWELL"
     gene            1126..1362
                     /locus_tag="PB779_002781"
     CDS             1126..1362
                     /locus_tag="PB779_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module antitoxin"
                     /protein_id="HDE0740264.1"
                     /translation="MNIKKRKIREVGNSIVVTLSKESLLQKGLKPGDTIFIDEDKMME
                     AIVKEESKIDLEIDMYVNQALSEYDAAFKELVEK"
     gene            1359..1772
                     /locus_tag="PB779_002782"
     CDS             1359..1772
                     /locus_tag="PB779_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HDE0740265.1"
                     /translation="MIYLSEKDIVKLNVIQIKKYSPRETIGVIDKNALSMAVNQPKQH
                     IFGKDLYPDKFSKAAVLLINLIKKHPFHNANKRTAFLAAYVFLKLNGYSLKMKNQEVV
                     EFVVEIATYQGDFDDLKEATTDILKKNSTKTDSKK"
     gene            2291..3241
                     /locus_tag="PB779_002783"
     CDS             2291..3241
                     /locus_tag="PB779_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toll/interleukin-1 receptor domain-containing
                     protein"
                     /protein_id="HDE0740266.1"
                     /translation="MERNSENKMTGRNPKVFISYSWENKENKEWARELADKLLENGID
                     AYIDQYDLSLGDRLPQFMEQQISDSDYVLIICTPEYKKKANNRTSGVGYEGHIISAEL
                     LSGKNERKFIPIIKEGRASEVLPTFLAGKLGIDLSDSQHYDENLDDLITTIFGVKRKP
                     ALGDIPRHIKGSPLLPIEHNENKDIEILGIITDKVTVPKMDGSRGSALYKIPFRLNRV
                     PSQLWKELFVRNWNSPPRYTTMHRPGIASVVDDEILLNGTTIEEVREYHRETLKLCIE
                     KSNTQEKKILLEEEQKKERENERVRSHKESVQKLADELEF"
     gene            complement(3238..>3820)
                     /locus_tag="PB779_002784"
     CDS             complement(3238..>3820)
                     /locus_tag="PB779_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDE0740267.1"
                     /translation="SIDQNEQRQIEEMRKFGAEKIFIEKQSGATITHRPIFQEVLDFV
                     RDQDIFIVEAIDRLGRNYDEIIDSVNYLKKKNVRLIITNLPIMAEAIGNPLLDKFIKD
                     LIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANTKDPQRRLVYRSIV
                     QDQENGVAISKIATDYNVTRQTVYRIKKELTIN"
BASE COUNT         1396 a          507 c          679 g         1238 t
ORIGIN      
        1 gtaattatat aataatttat gtttgtgcca ttaaacaatc ttaacagata tttcatttta
       61 tttatgtaaa acaacacgaa taattattgc ttcgtaaagt tatatgagta taagttaatt
      121 tactggaggt agtgcaatgc ttttttctga aagatttggt tttaaaaaat ggaggatatc
      181 atactgagag atagattgac agaccctctt aaaaatagtt tagcaaatgt gatttatgat
      241 atattacgag aggctgataa agtttatagt aattataatg gaaaagtctc atgggtaata
      301 tattcttttt taattaaaga gttttttaaa gaacagataa ataatagcta tgagttgggt
      361 tatcatttta ctgtttatta tgaagatatt atcaagaggt tagaagactt ggagtggtat
      421 gcttattatg atttattaga ggtttttgca agtgctaaaa tcttggataa aaagaaaaga
      481 gaggaagtaa ataaaattct ggagtcggaa aattctggtt acagattaag cgaaagcaat
      541 gaatttattc caatcacaga tgatatttct attaagtcta taaatgctgt atctgaatca
      601 ccatttaatt acgcaaaaaa tcatatccat aaatctctta catatataag cgagaaggaa
      661 aatcaagatt ataatactgt agtgagagaa gcaattagtg ctgtcgaaag ttgtcttatc
      721 gaattttcag gattaccagc taataaaaaa atactttggg aactgctata aaagcaatta
      781 aagacaaatc gaataacaat gtcgatctta catttttaaa accatttgag acaatgtatg
      841 gtttggcgag taataatgga atacgacatg cagaaaatga aaaaacaatt gtctcagatt
      901 tacctgatgc agttttggtg ttaacaacat gttcagccgt aattaattat ttgggagtaa
      961 aaatagcata tgactccaat aaatcatgaa aagttaaaat tcatccaaga gctacattat
     1021 aactattaat ttccaactct ttaaaagttt agtaattgaa ggaagtaata agggtgattg
     1081 aacaatacgg atatacggtg tatacttatc gtaggagttg atgatatgaa tattaaaaaa
     1141 cgcaaaatca gagaagtagg taattcaata gttgtaactt tgtcaaaaga gagtttattg
     1201 caaaaaggtt tgaaacctgg agatactatt tttattgatg aagataaaat gatggaagct
     1261 attgtaaaag aggaaagcaa gatagatctt gaaattgata tgtatgttaa ccaagcttta
     1321 tctgagtatg atgcagcttt caaggaatta gttgaaaaat gatctatcta agtgaaaaag
     1381 atattgtaaa attgaatgtt attcaaataa agaaatattc accgcgagaa acaatcggag
     1441 tcattgacaa aaatgcgctg agtatggctg taaatcaacc taaacagcat atttttggaa
     1501 aagatctgta tcctgataaa tttagcaaag cagctgttct gctaataaat ctgatcaaaa
     1561 agcatccatt tcataatgct aacaaacgta cagcattttt agccgcgtat gtttttctca
     1621 agctaaatgg ctattcacta aaaatgaaaa atcaggaagt agtagaattt gtagttgaaa
     1681 ttgctacgta tcagggtgat tttgatgact taaaagaggc aacaacagat atactaaaaa
     1741 agaattcaac aaagaccgat tcaaaaaagt agaagcaaac tagggattca gttaaatctg
     1801 aagatttagt ttgttcttta ttttagttta cataagatac attatgcgaa gttcattatt
     1861 ttaaaagctt aaataataaa cttttttata ataccaattt atttatgtaa accaatgacc
     1921 ttaatcgctt aagcaagcat gttatgtaat actctactct ctccaaaact aatgactatc
     1981 tattttcaaa gaagctagaa tgattatctg atcaaatgat aatttatatt taattcctgg
     2041 tctactgctc ttcttttaat caattaatgt ctaacgtact gtacacgata aagtaggaag
     2101 acttattttc aacttcggat tcattttttt aattcggtga aaatcactaa attaagagtt
     2161 tatccaagtt cattttagct gagaatacgc ttgaaaataa ttttgatgaa ttttcctgaa
     2221 ttaaaattta ttaacttgtt gagtgatata attgtaatgt attaccaaat agttagcact
     2281 tagattagtg atggaaagga atagtgagaa caagatgact ggtagaaatc ccaaagtatt
     2341 tatatcatat tcatgggaga ataaggaaaa taaagaatgg gctagagaac tagcagacaa
     2401 attacttgaa aacggtattg atgcatatat agatcagtat gatttaagtt taggtgatag
     2461 attacctcag tttatggagc agcaaatatc cgattcagat tatgttctaa ttatatgtac
     2521 accagagtat aaaaaaaagg caaataatcg tacaagtggt gttgggtatg aaggtcatat
     2581 tatctcagca gaattgcttt ctggaaaaaa tgaacgtaaa tttatcccaa taattaaaga
     2641 aggacgtgca agcgaagtac ttcctacttt tcttgctgga aagcttggaa ttgatttatc
     2701 agatagccag cattatgatg aaaacttaga tgatttaatt acaactatat ttggtgttaa
     2761 gagaaaacca gcattaggtg atatacctag gcatattaaa ggcagtcctt tactacctat
     2821 agaacataat gaaaataaag atattgaaat cttaggaatt atcactgata aagtaactgt
     2881 acctaaaatg gatggctcaa ggggttctgc attatataaa attccattta gattaaatag
     2941 agtaccaagt cagctttgga aagagttgtt tgttagaaat tggaattcac caccacgata
     3001 tacaacaatg catagaccag gaattgcttc tgttgtagac gatgaaattt tacttaatgg
     3061 aacaactatt gaggaagtcc gggaatatca tcgggaaact ttaaaacttt gcattgaaaa
     3121 aagtaatact caagaaaaaa aaatattgct agaggaggaa caaaaaaaag agagagagaa
     3181 tgagcgagtc agatcacata aagaaagtgt tcagaaatta gcagatgaat tagagttcta
     3241 gttgatagtc agttctttct taattcgata cacagtttgt ctagttacat tatagtctgt
     3301 tgctattttt gaaatagcaa caccattctc ctggtcctga acgatgcttc tataaacaag
     3361 gcgacgttga ggatcttttg tgttcgcact gtataactta ggacgtcctt tatagacgcc
     3421 gtttgcttta gcaatcttta tcccttgtgc ctggcgtcgt tttgattcag tacgctcttg
     3481 ttcagcaatc atggccaaga tttgaatgat taggtctttg ataaatttat ccaggagagg
     3541 atttccgatt gcttcagcca tgatcggtaa attagtgata ataagtcgca catttttctt
     3601 ctttagataa tttactgaat cgataatctc gtcataatta cgtccaagtc gatcgatagc
     3661 ctctacaata aaaatatctt ggtctctaac aaaatctaga acttcctgaa aaatcggtcg
     3721 atgagtaata gtcgctccag attgtttctc gatgaaaatt ttttcagcac caaattttct
     3781 catttcctcg atttgacgtt gttcattttg atcgatcgat
//
LOCUS       DAMEEU010000135         3729 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.141, whole genome shotgun sequence.
ACCESSION   DAMEEU010000135 DAMEEU010000000
VERSION     DAMEEU010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3729)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3729)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3729
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.141"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            270..869
                     /locus_tag="PB779_002785"
     CDS             270..869
                     /locus_tag="PB779_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0740268.1"
                     /translation="MKSVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLRDVLEISRGRVIVKERLAMKEQKTAKHNSVFISNKLRKVILDYVQSEFPEQ
                     LQAQDFSKYLFPSRKGADTPLTRQSLWRIIHEAGTAVGLKEIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            918..1634
                     /locus_tag="PB779_002786"
     CDS             918..1634
                     /locus_tag="PB779_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HDE0740269.1"
                     /translation="MNEEKQPNFPDKYHLSRKESVYLLKKNIVELVYNAGKFEGLNTT
                     LLQTEGIIKYNRANNVAVDDVLTVVNLKRGFEMLLNDVQEPLLETSKRINRIVAAEDA
                     LFPGEIRTGGVELSTIQGRYVPPMLTEDEVNNQYGEIMNQEISDTEKALRLFLFISKN
                     QIFWNGNVGTALLIANKIMFSNGLGLLSIPENVFMKFNELLSKYCNSNLLVNESNIIS
                     FLYEQCIFGINYLKIIQHTI"
     gene            1648..2427
                     /locus_tag="PB779_002787"
     CDS             1648..2427
                     /locus_tag="PB779_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002396205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HDE0740270.1"
                     /translation="MMTIDEAKQLATYFSVGSAGYILDFTNVTWNIFTKKIVGIEIQN
                     HYGGSKGVSFQKFLLDDQFDDSLKNRLIQSLKGIMDRDKKYESTEMNPIVQLLFEEVF
                     KEDTSTALRKMKFSSEIDLLYIRQLPIRIQTDIKNKDFDSVLTKANTLIDEVLKFIIE
                     NTEGPSVNINLFKSKELRKEVFGRLNIKTEKDMDNRIKALVGALNTLSDKILEMRNSQ
                     GDAHAHGSNRIVIKEEEAILVANSSMVLCEYVFTKYKGLNR"
     gene            2510..2866
                     /locus_tag="PB779_002788"
     CDS             2510..2866
                     /locus_tag="PB779_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDE0740271.1"
                     /translation="MEKISFETFKRPNGHDEFLEWLETLPKKDSAKLLRTIEETEKNG
                     MLVAQRLKWVKKLDTNLYELRSKVGSNIQRAIYFHVDNGRYVITHGFTKKTEKTPITE
                     LKHAKELREEWFTNDD"
     gene            2856..3122
                     /locus_tag="PB779_002789"
     CDS             2856..3122
                     /locus_tag="PB779_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740272.1"
                     /translation="MMIKKLIEEKKKDKDFAEAYDREGRKLETAVALYHAREEAGLTQ
                     AELAQKAHTTQSTIARIERGDNVSFDKLDDIARALGKKLVVEFA"
     gene            3281..3559
                     /locus_tag="PB779_002790"
     CDS             3281..3559
                     /locus_tag="PB779_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740273.1"
                     /translation="MKTINLIKVFIASPGDIAAKRNEVEETIYRWNIENTDNTKVILM
                     PIRWETNAIPTYVNNSSGQSVINKQIVENRVLLQSFKNKISFCIISSF"
     gene            complement(3556..>3729)
                     /locus_tag="PB779_002791"
     CDS             complement(3556..>3729)
                     /locus_tag="PB779_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010868911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDE0740274.1"
                     /translation="HRSIKRRHKLYQSLRTASTTIKGMETIRGIYKKSRKEGTLFGFS
                     VCTEIRILLGIPA"
BASE COUNT         1375 a          537 c          730 g         1087 t
ORIGIN      
        1 tttgaatttt cagaatagaa taacttaaaa gtactgacaa attttttaaa ggggcaatat
       61 taatgttctg agataatcaa atcttaccga aaatatcaaa agtccaatgt gacacaattg
      121 gattttgtca cattcgttaa aatcgctcca tccttagagg ctctaatagg aaatcacttt
      181 tcttttagcg ccttttttct atagcttgtt taaatgtgac ttattatctg ttataatcgt
      241 attaagtaac atttgagagg tgtctaaaaa tgaaaagcgt ggaaccgatt cgcgacaaaa
      301 aaaagatcga tgccatgaag gccattttgg cttccggaaa atatgggcaa cgaaatttgg
      361 tgcttttttc gatcgggatc aatacagcct atcgaatctc cgatttaaga cagttaaaat
      421 taagggatgt gctagaaatt tcccgtgggc gggtgatcgt caaagaacgt ctggccatga
      481 aggaacaaaa aacggccaaa cacaattcgg tcttcatttc gaacaaattg cgaaaagtga
      541 ttcttgatta tgttcaatcc gaatttcctg agcagttgca agcacaagac ttcagcaagt
      601 atttgtttcc aagtcgaaaa ggagcagata cgcctttgac ccgacaaagc ctttggcgga
      661 tcattcatga agcaggaact gcagttgggt taaaagaaat tggtccccat tcgatgcgta
      721 agacctttgg ctatttttta tacaagcaag gaaccaaaac agagatcatt cagtcgctgc
      781 taaaccattc ttcacaacgg gagaccttac gctatattgg aatcacccag gaagacaaag
      841 atactgcagt aaagagtttg gatttatgac agaataatgc cctatataat agaaggaaaa
      901 attcaagagg tgagaaaatg aacgaagaaa agcagcctaa ctttcctgat aaatatcact
      961 tatctcgcaa agagtctgtg tatttattga agaaaaacat tgtagaactg gtgtataatg
     1021 cggggaaatt tgaagggtta aatacaacgt tgttacaaac agaagggatt attaagtata
     1081 atcgggccaa caacgtggct gtagatgatg tcctgaccgt cgttaactta aaaagaggct
     1141 ttgaaatgct tttaaatgac gtacaggagc ccctgttaga gacaagtaag cggattaatc
     1201 ggatcgttgc agcagaggat gcgctttttc ccggtgaaat acgaaccggt ggggtagaat
     1261 tatcgacgat tcaaggaaga tatgtgccac caatgttaac tgaagacgag gtaaacaatc
     1321 aatatggtga gataatgaat caagagatat cagatacgga aaaagccctg cgactgtttc
     1381 tattcatttc gaaaaatcaa atattctgga atggtaatgt gggtacagcc ttgttgattg
     1441 cgaataagat tatgtttagc aacggtttag gactattatc aatacccgaa aatgtattta
     1501 tgaaatttaa cgaactttta tcaaagtatt gcaacagtaa tctattagtc aatgagtcaa
     1561 atattatatc atttttatat gaacagtgta tctttggtat taattatttg aaaataatcc
     1621 aacatacaat ttaagaggta taagtaaatg atgactatag acgaagcaaa acaattagca
     1681 acttattttt cagttggttc agcgggatat attttagact ttactaatgt aacgtggaac
     1741 atatttacaa agaaaatcgt agggattgaa atacaaaatc attatggggg ctcaaaggga
     1801 gtatcctttc aaaagtttct gcttgacgat caatttgatg attcgttaaa gaatcggtta
     1861 atccaatctt taaaaggtat tatggatcga gataaaaaat atgaatctac tgaaatgaat
     1921 cccatagttc agttgctttt tgaggaagta tttaaagaag atacttcaac tgcattaaga
     1981 aaaatgaaat tttcaagcga gattgattta ctttatattc ggcagctacc cattaggatt
     2041 caaacagata ttaaaaacaa ggattttgac tctgttttga caaaagcaaa tactttaata
     2101 gatgaagttc taaaatttat tattgaaaat accgaaggac cgagtgttaa tattaattta
     2161 tttaagtcaa aagaattaag aaaagaagta tttggccgcc tcaatattaa aactgaaaaa
     2221 gatatggata atagaatcaa agcccttgtt ggagcactca atacattatc agataaaata
     2281 ctcgaaatga gaaatagtca aggagatgct catgcacatg gctcaaatag aatagtaatt
     2341 aaggaagaag aagcaattct tgttgcaaat tcttctatgg ttttgtgcga gtatgtgttt
     2401 actaagtata aaggattaaa tagataataa aatgcatatt ttatagtata caattcgaat
     2461 ttttatgtta tatactataa tataaaatca atatatgata taattgggta tggaaaaaat
     2521 atcttttgaa acatttaaaa gacccaatgg tcatgatgaa tttttagaat ggttggaaac
     2581 attaccaaaa aaagatagtg cgaagctttt acgtacaata gaagaaacag aaaagaatgg
     2641 gatgctagta gctcaacggt tgaaatgggt gaaaaaatta gacactaatt tgtacgaatt
     2701 aagaagtaag gtaggatcaa acatccaaag agccatctat ttccatgtgg acaatggaag
     2761 gtatgtcatt actcacggat ttactaaaaa aacggagaaa acaccaataa ctgaactcaa
     2821 gcatgcaaaa gaacttagag aggagtggtt cacaaatgat gattaaaaaa ttgattgaag
     2881 aaaagaaaaa agataaagat tttgcagaag catatgaccg tgaaggaaga aaactcgaaa
     2941 ctgcggttgc tctttatcat gctcgggagg aagcagggct aactcaagcg gagcttgcac
     3001 aaaaagcaca tacaactcaa tctactattg ctcgaattga gagaggggat aacgtatctt
     3061 tcgataaact tgatgatatc gccagggcat taggtaaaaa gctggtagta gaatttgctt
     3121 aaaagcgagt tgaaaatata tctataatag gctcctaact aatcaattag tttagtgggc
     3181 ctttttttac tagatagata aaggttgtac tatagtgtaa aagacaataa attttatact
     3241 aaaattactt taaagagaac tagagagaaa ggtacaataa atgaaaacca taaatcttat
     3301 aaaagtattt atagcatcac caggtgatat agcagcaaaa aggaatgaag tagaagaaac
     3361 catatataga tggaatatag aaaatacaga taatacaaaa gtgattttga tgcctatacg
     3421 atgggaaact aatgcgattc ctacttatgt aaataatagc tctgggcaaa gtgttattaa
     3481 taaacaaatt gtagaaaata gggttctgct gcaaagtttt aaaaataaaa tcagtttttg
     3541 tattatttct tcattttaag ctggaattcc caataatatc ctgatttcag tgcagactga
     3601 aaagccgaag agagtgcctt cttttcggct tttcttgtag attcctcgaa tggtttccat
     3661 ccctttaatt gtggtggaag ctgtacgtag actttgatac aatttatgtc gacgttttat
     3721 cgatcgatg
//
LOCUS       DAMEEU010000136         3704 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.142, whole genome shotgun sequence.
ACCESSION   DAMEEU010000136 DAMEEU010000000
VERSION     DAMEEU010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3704
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.142"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            525..1565
                     /locus_tag="PB779_002792"
     CDS             525..1565
                     /locus_tag="PB779_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HDE0740275.1"
                     /translation="MTDFNFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCSVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFIPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAETESGISIIFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNSE
                     SFPKTITKDWLE"
     gene            2412..2744
                     /locus_tag="PB779_002793"
     CDS             2412..2744
                     /locus_tag="PB779_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HDE0740276.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYAGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            3363..3593
                     /locus_tag="PB779_002794"
                     /pseudo
     CDS             3363..3593
                     /locus_tag="PB779_002794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 family protein"
BASE COUNT         1344 a          503 c          669 g         1188 t
ORIGIN      
        1 taattttttt cagattaaca cagtagtatc ttattaaata agttaatttt aatggtagta
       61 cataattatt atatatatct gacattggta gtacttattg tattttttag tagtatataa
      121 tctattgttt tctagcctaa agccttgtct tataagaaga atataatata tactactgaa
      181 ataaggtagt atatattact agtaatggta gtatgtttta tatgcataag gtagttctta
      241 atttattttt tgttttgaca ctggtagtac ttaattatct ttaattttaa aactaaattt
      301 tattcatacg ttcttctggt agtatttaat tataaataat atttatttaa agtagttctt
      361 aatgacttta aaggtagtac ataattcatt ttatttctga ttttaggtag tatttaatta
      421 aaaaacagtt ttaatgcgtt tgcatttttt atttatcttt gctattttcg aaaagagtag
      481 gtaattttac ataaataaaa caacgtgaaa gtagaggatc tacaatgact gattttaatt
      541 tttttaaggc ggatagagtt tacaacgaat tattttatca atttccaaaa gtctttattg
      601 tttctgacga atacaaaaaa atgaaagatt caactaagat tgcctatatg cttttaaaag
      661 caagattaga gatcgcaatc agcaaacggc aaatcgatga agaaggtaat gtttatttta
      721 cttatacgac aaatgaacta tgtagcgtat taaactgcca aaaacaaaaa gcgatagcaa
      781 tcaaaaaaga gttggaatcc tttggtttat tattacaaaa gcagatggga tttaacaaac
      841 agttagggaa aaataatcct aatagactat atctagcaga attaaaagtc tcagaaaatg
      901 atatctactt actcgaaaaa tttgatagag agaataggga aaacgttgat aaatcagagg
      961 gtatgaaaat catacccacc ctcgacgaaa aatcagacgc tgaatccctt ggggctcaag
     1021 agggtatgaa aatcataccg tgccaaaacg ttgataaatc agagggtatg aaaatcatac
     1081 cagaacttaa taataatata ttagacacta atagacacaa tatagacact gaaaaagacc
     1141 gcctacaaga tcaattgttg ttagacaatt ttgagacaat tatgacaaac gacagcattg
     1201 ctacgtttat ccctgaacga gtattaaatt taataaaaac attttcttca agttacagtg
     1261 aagctcaaaa aactgtccag actattcata atgcaaagaa aaaagccgaa acagaaagtg
     1321 gtatttcaat aatttttgaa gaactcgata gttattatgt caatgcagaa caagaattat
     1381 acacgacact gttaaaagcc tatcaaaaat taaaaaccga aaaagttgaa aatatccaga
     1441 acctgatttt tgtctatgta aaaaattggt ttatcgaaaa accaatagct gctaaagtat
     1501 caagtgaaaa acgtttgaat tctgaaagct tcccaaaaac tattacgaaa gactggttag
     1561 agtgaaattt cactgacaaa ttgattgttg cttcatggag tagcattaaa attaaaaatt
     1621 ttttattatt ctaattatat tacaaatgtt acaaagaaat agctatttta atagaattta
     1681 tgagttaaaa tattatgata aaaatcacaa acgtagcttt ttacgtcata agtgttaata
     1741 gttaataatt aatttccaac acaaaaaaga gaacaaacgt ttgcatgttg ctgtttttta
     1801 gttataataa tacgcgaaga gaggtaattt cattttttaa aaaagctaaa aaccttgata
     1861 ttacttcttt tcaggcaata cgaatattat tcgcttacat ttttttgtat aaatttagtt
     1921 gttttaaatt taattgtctg ctacgcttgt gatgaattaa ttttcgttct gcacttttgg
     1981 acgataaatt tggacaattg aaaatacaaa aaaaagaaag gccctgtgag actcggaagg
     2041 ctggtaacct tcgtcgacgt ccacaggtgg cattaagaca acctttaatc ccttaatgcg
     2101 tttacctttc agtgttacgg tattacccgc aacggattta gtataacaga tattcaaaag
     2161 tgataccact ttttttggct gtgttaaggt taaaaatacg tgatattacg atgaatctat
     2221 gcctaagcat aatgttataa aaatgtccgt gtggctcttt gccgtatgac gaacgctgaa
     2281 attagaggga acgcatgttt ggatgcgttc cctctttttt gtttgtcatg aacgaaaatc
     2341 aattctctat ttttgaaaaa taacaagaaa aacttattaa aaatatttaa agtaagtggg
     2401 tggattattt tatgtcatat acaggaattt tgagtctcga agatatttgt cactacggta
     2461 aacggtgtac cgctacagag aaaatcacga agaaactatc aactggccaa agtaaaaccg
     2521 ttgtgcagtg taagaaatat ataatccaga aagacaaagt ctcagaggaa atgatttatt
     2581 acgctggtaa acaaaagcaa ataattttaa aagatcctat ccctttaaaa gaactatatc
     2641 caacaatcaa acatgtttat gaccaaaacg gtgtactgat tggtcgaaga aaaaatggag
     2701 tcttgcgttg taccgcaaaa gggatggggc gtttaatcag ctgaattgat cattctcata
     2761 acttgtattt tatcgttttt cgcttgcttg aaaatattgt cgagacttct aaaagaactt
     2821 agaattacta gaaaaataag gagtagactt gatctatcaa caattccttt cggggggtga
     2881 cggggtaggt ttttacgatt ggtaacgtaa aaaattggtc aatcgagtaa atgcccttgt
     2941 ttggatagtg gtgaaatgaa tttgtgtaaa taatatgcac agagtaaaca agagggaatt
     3001 tagaagttag acaagttaga atagcgccta gattaatcat gagcagctac taagggatct
     3061 aggctttgac gcaaactcat ggaataagga gtaggtcttc tcgtaatggg gaggacgcac
     3121 aagaaattgt gtcgtgtgct gcagtacatg tagatacttg cgaggacgtt ggtcattgga
     3181 tcaatcgagc atttaccgat ttctactagg gtttctcgtt tcggacgcca taaacgagtc
     3241 gatatttttt atgtattttt aagtaaacga aaaacgataa aatatgaacg agtcctgaat
     3301 aaagtgaaaa aattgatata aaacatagag aaaatgaaat ttacgtaatg gaggaatgac
     3361 aaatgaaaaa ttatgatccg aatatacgat tgggcacaca tactattaag gtttctttcc
     3421 aacgttggga ttacaaagga tttgtgacgt ttagaagagg cggaaattgt aaaggattag
     3481 atgttttagc attagacgag gatgatttat actatcaaaa attgactgat aatccaattg
     3541 gattcggctt gctacctgaa gatgatgaag gtaatgaatg gtttaacaga attaggcaga
     3601 agtcgcccat cctctatagg tgggtgatga atgccgttcg gtatgagggt taccgttggt
     3661 aactcgaaga ccgacaacta aggcgtattg cctttttatt ttgt
//
LOCUS       DAMEEU010000137         3554 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.143, whole genome shotgun sequence.
ACCESSION   DAMEEU010000137 DAMEEU010000000
VERSION     DAMEEU010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.143"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(52..1518)
                     /locus_tag="PB779_002795"
     CDS             complement(52..1518)
                     /locus_tag="PB779_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HDE0740277.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1906..2502
                     /locus_tag="PB779_002796"
     CDS             1906..2502
                     /locus_tag="PB779_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDE0740278.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAEEKEYMNDADRFRVFG"
     gene            complement(2560..3042)
                     /locus_tag="PB779_002797"
     CDS             complement(2560..3042)
                     /locus_tag="PB779_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740279.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3148..3345)
                     /locus_tag="PB779_002798"
     CDS             complement(3148..3345)
                     /locus_tag="PB779_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740280.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
BASE COUNT         1211 a          710 c          577 g         1056 t
ORIGIN      
        1 aaaaaacagg aactgctgca aataagcaat tcctgttttt atgttcattg attaatgaat
       61 agagcccatt agttttttga ttggttcttt cacagtaaat agcaagatac caccgacgat
      121 tgctactgca ccgataatac cgaagtaagc agattctgtt cccggtgtgt agaagcgtgc
      181 aatttgtgca ttgattgctt gtgaagaagc atcagctaag aaccaaatag cgattgtttg
      241 tgattcaaat gctcgtggtg ctaattttgt tgtcacagac aaaccaactg gtgaaagaca
      301 caattcagca ataaccacga tgaagaaact tcccaacaac cacaatggac ttacttttcc
      361 acttgtacca taaagcatac ccggcaacat caatagcaag tacgataatc ctgcaaataa
      421 aagtccaaga gagaatttca ctactgtaga tggttgacgt tcaccaagtt tcgtccacat
      481 cgttacgaat actggtgtca gaataaagat gaaaattgga ttcaatgatt gataccagct
      541 tgcttggatc gttacaccaa atagcgtaga ttgtgtacgt tcactagcaa ataaagctaa
      601 gatagatgaa ccttgttctt gtaatgacca gaaaatgatt gctgcaagga ataatgggat
      661 ataagcccat actcttggtt tttcttcagc agttacatct tttgaagtca gcattttgat
      721 aaagtaatac aacggtaaga taatccccaa tacactgatt gtattgacaa aaaagtcaat
      781 tgtcagatga ccagttagtt gtgccccgcc gaatactgca gcgataacaa caagtgcgat
      841 gatcaagtta cggatgaatc ctttacgttc ttcagttgtc aaaggattcg gcggtgttgt
      901 acccactccg tctaatgtct tgcgtccttg gatgatgtat tgtaataatc caaagaacat
      961 cccaatagca gctaaagaga accctaaatg atagttatat tcttgaccga ttgtaccaac
     1021 gattagtggt gctaataatg cccctaagtt gacacccatg taaaaaatcg aaaatcctgc
     1081 atctcttcgc aagtcagtct ttgaataaag atgtccgacc atgccagaaa catttggttt
     1141 caaaaaggcg gttccgataa taatcaatgc catcgaaaca aacaatgtac ttacaccaaa
     1201 tggtaaagcc aagacgatgt ggccaagcat aatgaaaact ccaccgaaga atacagtgcg
     1261 ttttgctcct aacactcggt cagataccca tccgccgacg atactagaca tgtagatcaa
     1321 agatccgtag atcgacatga tagctaatgc tgttgctcgt ggtaatccaa gtcccccgtt
     1381 ggcaactgta tcgtacatat aatagataag taatgcacgc ataccgtaat aactaaatcg
     1441 ttcccacatc tcagtgaaga acaaagttga caatcccttc ggctgcccga agaagccctt
     1501 gtcttgctgt ttttccataa tctatacccc aattctttaa attttcagaa aatattatac
     1561 atctttaccg aaaaatttaa ctaaaaaact tatttaagaa atataaacta attttctata
     1621 aaagcaagta atttttaatg gcaatatcat aaaaaaaaag aagatagaga tttaataatt
     1681 atatatcagc tgtttttttc aaataagcaa aaattcctaa aacacaacaa tgaaagcgat
     1741 aactaagaaa atccttacat aacgattttt cttattaaaa ttgttttttg aacttcgctt
     1801 attttttgtg agcatatctg tttacttact ttttgtaagg tgctatactt catttcgtaa
     1861 tcaattaaaa aaatgcaaaa cgcaaatcaa aggagaaatt ttattatgac aacttttact
     1921 gacactttga aaaaccgccg ttcaatctat catctaggac gtaatgtttc actttctaat
     1981 gaagaattaa caactttgat caaagaagca attaaagaaa gcccaactgc tttcaatgct
     2041 caatcaacac gcgcagttat ccttttcgga gatgcacatg aaaaactttg ggaaatcact
     2101 gaagaagcac ttcgcccatt gactccagca gaagctttcc caaatacaca aaacaaatta
     2161 gctggtttca aaaatggtta tggtacagta ttattcttca aagatactga cgtggtaaaa
     2221 ggtctacaag aacaatttga attatatgca gacaacttcc cagattggtc agaacaatca
     2281 aacggaatcg caacagctaa tacttgggta gcattagttg ataaaggatt gggcgcaaac
     2341 ttgcaacatt acaacccagt tattgacgaa gcagttgcaa aagaatggaa tatcccttca
     2401 aactggaaac tacgttcgca attagtattc ggttcaccag aaacaccggc tgaggaaaaa
     2461 gaatacatga acgatgccga tcgcttccgc gtatttggat aattttattt gaaataaaaa
     2521 acagaggttg tgacaaacat cttgtcgcaa cctctgtttt tattctggat caatcataat
     2581 atcaatctct gcctcatcgt ttaagcgttg ggacaaaaat ggaactaatt cttctaatga
     2641 tgcagaaaat ttcagcatcg gtcctcgcca tccgtttcgg aaaaaattca tttttacgat
     2701 tttagaacct tttggctgat ataatacaat tttattgatc tcagaaaaag gaacaccttt
     2761 tttgtcaaag ctattcaaaa caagtccttc ttctgtgatt cctctactgt ccaacaaaaa
     2821 actaataaaa atcattgctg acaagatccc ttttgccaat tcatctgctg taggatgact
     2881 gatgagtgta taccaaatga ctagtgacac taagaagggt atcaccaagt agacccatcg
     2941 atttcgcaca gtccgataaa taatttcttt tcgaaccagc caaagaaata aaaacatcac
     3001 aacaacgaat aaaaacaata gaaccgtaaa gaatgttacc atgacaactc gcctcgcttt
     3061 ttcttctcca gaaaatagga aaagaatact gatttacctt ctcaaagaaa ttggacttgc
     3121 agcacgccgc acgtccaatt gttttcttta ttcaaatgta tcatattttg caacaaccat
     3181 gcttgctttt tcatctaata attcttggtc ctctgcagca cattgggcaa ctttgaccac
     3241 ggcgcagttt gtcatttttg atacaacttc accaatgacc gtttttgtaa aaccaattgg
     3301 tttgcatgca tattgttctc ctaaattaat catttcttcc gtcatcaaaa tcctcctaaa
     3361 ctgctggaac ttttctccac attaccactg ctatttcttt ggagatttaa ctcattgatt
     3421 tttatttaca gttaaaaatc aaccttacag gcattatagc gtactgtttt cgttttcaca
     3481 attaaaacag ctgttgtatt tagaagaatt tttttcaaaa aattaaaaca tattccttaa
     3541 aaactaatta tttc
//
LOCUS       DAMEEU010000138         3381 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.144, whole genome shotgun sequence.
ACCESSION   DAMEEU010000138 DAMEEU010000000
VERSION     DAMEEU010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3381)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3381)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3381
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.144"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..2232)
                     /locus_tag="PB779_002799"
     CDS             complement(<1..2232)
                     /locus_tag="PB779_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740281.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
     gene            complement(2904..3172)
                     /locus_tag="PB779_002800"
                     /pseudo
     CDS             complement(2904..3172)
                     /locus_tag="PB779_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
BASE COUNT          933 a          753 c          542 g         1153 t
ORIGIN      
        1 accggtttgt agcgtttctc cttctcggtt ctgtaactca aaaacagctc cttgaaggac
       61 ttcaccactg ccttcagcat gtttaattag ttcaacacca cccgtatcaa ggatgttttc
      121 aatggttaac gtcacttctt ctatggagta ttcatttata aaaacatcat gtaccgtcgc
      181 atctaaaaga tacccttccg gtgcttctgt ttctcggact tgatagctac ctacaggaag
      241 cggttcactt aaaaattctc cgttttctgc cgttatacct tcttgtatca cttgtgaatc
      301 gcttgataaa atttcaaatt ttgctcctgc cagcctttgg ccattctcat cagttttaat
      361 tactttaata cgcccatcga ttttccttgt tcttacagta ctcgtattca atcgattgtc
      421 actattcaca agcgttgcaa agtttaaaat ttgatcgccg accgcatacg cctctacatt
      481 gaccttaaaa gagagggtaa aacttgtcgg accaccaatc gtattattcg cactgaaacg
      541 aactattcca ttattgactt cggcatcaat gaaagaggga atatctgata gaaatgacac
      601 aaattccatg ccttcttcca aaacatcttc aataacaagc gtatttcttg ttccagaaaa
      661 catcgagaca tgcagagtat acgttagttc attttcattg agattgataa catttttgtc
      721 cacacttttt cttaaagaga ttgccggaag attactttca gggattctca agcggtagtc
      781 tcggctcatt acctgattat tgtaggtcat actcgctcga ttccgagaaa acccatcctc
      841 ttgtcttcct tcattgaaca agtcgacatc ggtcacttca agagcatatt caataaaata
      901 cgattgaccc tctgctagat taccaaagtc cacaacaagt gtattcgttt ccttattaaa
      961 agatactttg tccacaaatt cctcggaaac ataatgagtt ctaacgtttg cttcacctgg
     1021 attcgttact tctgcgatcc gaaccccacc tgaaataggt tctctatttc cagtggaact
     1081 ccatgtagtc ggattcggtg ccaaagttgt tccttgcggt agtacatcgg taaccactac
     1141 accgtctttt cgtgatcctt cataatttac ctgcaaaata aatttattac tgttggtcac
     1201 gtcttgcccg tcaatcagca gattcccaag atttccttgg ctgtcgattt ctctagagcc
     1261 atagtataat ttcgaaaaaa tgggtcttga tgaaggaata ggcgtaattg aaaattccgt
     1321 gtttgctgct cgctcagcat aagtaagact cacttgaaag tcattatttg gctcagtacc
     1381 gcctgattga aagaaagcaa cttcaaacgt gatactgaat gtatacgact gagcggcttc
     1441 atttaatcct tcataatcaa aggtaaatgg aaaaacaacg tctgtgcctt cttggtaaaa
     1501 tgccagtggc tttaaaggtg aatcatcagc gacctccact ctaatgaact caattaagcc
     1561 aatcgatgct ctaggaactc gtacgaccat ctccccatat tcttcaagaa tatcgccagc
     1621 gcctccttga atgtatccct ttaacgtttg tgtatgcctg ctcggcaaag tggggcgctc
     1681 agcagagatg ccgatgtcat aattcaagag ctcctcttgt ctttcaatct gagattcctg
     1741 cgttatagat ggctcagatg atctggcttc attaaaagat tcacttaagc tttcttctgg
     1801 tatattaaaa gattcacttg tgctttcttc tggtacatta aaagactcac ttgtgctttc
     1861 ttctggtaca ctgatttcta ttgagaccgt atttgattga atatcaccgc ttcttgcggt
     1921 caattcgtat ttacctgaat gctgggaaga ataagtaatc agacgttcgt aatcattgag
     1981 ttgcttcact tccccttcaa tcaaatcctc actcttatca atgaccaatg catttagcag
     2041 gtctggtgtt cctctgactc gcaactggaa ctgctcaccc aaagcagcct cctcttgatc
     2101 aacttcgatc gtcagcgaac gctctggctg ttctgctaaa gactcagcta gaaccgttat
     2161 gttcccaaat tgattgatca caataagcat aactagaaac atacttaaca gtttatgaaa
     2221 tttgttcctc actattactc ccccttataa ttttgactaa acaacaaggt acccgataat
     2281 tttctaaaaa gattccccaa ctcaaaatgg ctgcgttacc tccctcgtat tttcggttca
     2341 actcaagcgt tgcaatgtaa gctgtaaaca aagctaatga ttgccgattg tcttctgttg
     2401 attgattcga tagctttgta tgacttttag ttgtccgtgt ggcttaacca taattatgat
     2461 ttcacgattc ctcctgccag tgccttgcac aagctggagc gtaaccctaa tagttatttt
     2521 gttaatgtac ttatatactt ttatactttt ccattagaaa caatcactaa atcgttgata
     2581 ccaaggtcag actctagaat ttcatcagtg agtccctgta ttggttaacc ttcatcaatc
     2641 ccaaaaaaat atatcaatgc ttagcatcaa aatgaatata tagtttagaa tacttgggat
     2701 tcatcgataa ctgatcgctt atttggccat attatttggc acttggttca actaaacgca
     2761 tttaggatgt tccttcattc tcgtcatgga tgttctcaaa ccgtcattac taataaactg
     2821 tccaccgaat cgatggttca tttcttgcat tttccacgtc caattactct ttttgctctt
     2881 tatttgggcg tagtttcact ttcttaactt gtatcgtctt ccatcaactc cttaatcatc
     2941 ttcttagctt tattggctcg gtttccttgt aaaaggtatc tacaaatagt gacaatctgt
     3001 attaaatctt catcattttc tgtaatgtca ataatttcta tattctgtac catatattgc
     3061 aaagggtttc actaagttca taaccgaagc gaattaaaca acttttgtat agaataacta
     3121 ccttttctat ttttccattg gtaattctat ctattaattg gtttaatcct tttgttgtag
     3181 ttgattccac taccaagatg attctctcga attttaaagc ttgaagatgt attgctattt
     3241 ttgctaactg gcgtatttgc aactattttt cccttctatt cttccttcat tgattcccct
     3301 ctaaaattac tatccataaa aaattgcata aatgacaata gtatttatat tagtcatact
     3361 gctttttaac acagcaaatt c
//
LOCUS       DAMEEU010000139         3360 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.145, whole genome shotgun sequence.
ACCESSION   DAMEEU010000139 DAMEEU010000000
VERSION     DAMEEU010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.145"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..206
                     /locus_tag="PB779_002801"
     CDS             <1..206
                     /locus_tag="PB779_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="integrase core domain-containing protein"
                     /protein_id="HDE0740282.1"
                     /translation="KVEFVYQYTFETLQQLDLELFDYVNWWNHLRLHGTLGYETPVGY
                     RNQRLAQRILDNELGCANASEAV"
     gene            341..562
                     /locus_tag="PB779_002802"
                     /pseudo
     CDS             341..562
                     /locus_tag="PB779_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208413.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            562..909
                     /locus_tag="PB779_002803"
     CDS             562..909
                     /locus_tag="PB779_002803"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740283.1"
                     /translation="MRKRTIKTQLAVSFLAIATLIIGSISLVALSLMNNHFSKYVEER
                     QEDLLNQYVYTIDLLWLNSGETWNSEELAALSEKVLENNIYFSIEDEQGNMVWELTGK
                     DLKSAQEKLKKMH"
     gene            906..1955
                     /locus_tag="PB779_002804"
     CDS             906..1955
                     /locus_tag="PB779_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HDE0740284.1"
                     /translation="MKVSEKNSVKLDETIEVKKKLINDGNEFGKVTFYYFGPFAYTEH
                     DALFISSMKQSLMYVAIAALLVSFILASWISARLGLPLKHVSDFTHKLTRGEYADKIP
                     QETSIIEINSLIDSLNDLSNQLEKQHGLRKRLTTDISHELRTPLATLKGNVEGMIDGV
                     WKITPERLQSCYDEIDRLTRLIGNIEIINKIEAKYDHLNKTEFNIYKLIESVIENFAS
                     KIESKNLHVEIQGDNINISADKDKMNQVVINLLNNAIKFTQKEGTIKFSISKNKDHVL
                     LIVEDNGIGIEKDQQLHIFDRFYMADPSRSRALGGQGIGLAIVKSVIEAHKGSITVKS
                     KLGLGTKFVIKLPFQ"
     gene            1970..2176
                     /locus_tag="PB779_002805"
     CDS             1970..2176
                     /locus_tag="PB779_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740285.1"
                     /translation="MFQKQIKIAKLVCECWAKKIFFQLISIDSVEKVHLDILSNSVVI
                     FSKKDLSIATIKKEVFGLQIYEMT"
     gene            2197..2793
                     /locus_tag="PB779_002806"
     CDS             2197..2793
                     /locus_tag="PB779_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhK family protein"
                     /protein_id="HDE0740286.1"
                     /translation="MKTVKKMTKLVFASLGIIVFLGACSNQSESNNSNSTNEESTSTA
                     SSEMNSMEGMNHEGMVPSSMKDAANPKFPVGSNVILLGDHMEGMKGANAQVVGAFDTT
                     MYEVSYEPKTGGPMVNNHRWVVQEELKDTETVANEGDTVILNADHMDGMMGAEAKVDK
                     SITGTVYVVNYTPTDGQEEVKNHMWVTEDEMEYDENNE"
BASE COUNT         1204 a          477 c          667 g         1012 t
ORIGIN      
        1 tgaaagtaga atttgtctat caatacacat ttgaaacctt acaacaattg gatttggagt
       61 tatttgacta tgtcaattgg tggaaccacc ttcggttgca cggtacactt ggctacgaga
      121 caccggttgg ttaccgtaac cagagattgg cgcagcgaat ccttgataat gagctcggat
      181 gtgctaacgc tagcgaggca gtctaacttt aactgttagc tcctgccgaa gatcgtcaca
      241 tccgaggagg ctcattgtca aggacaatcg gaatagcata cggaaagaag ttctgcacct
      301 tataaaattt gtcaaaaaaa ctgttgccat tccacttaaa acaactgaat ttgatattct
      361 acacgctcta atgtccacac ctaataaagt cttttctcgt agtgatttga tagagaaagt
      421 taagggaata gaatttgatg gactagatag gagcatcgat tctcatataa aaaacttaag
      481 acataaaatt gagaatgatg ctaaatcacc tatgtatatt ttgacagtcc atggtacagg
      541 atacagattt ggtggccact aatgagaaaa agaacgataa aaactcaatt agctgtttcc
      601 tttttagcaa tcgcaacatt aataatagga tcgattagtt tagtcgcatt aagtttgatg
      661 aacaatcatt ttagtaaata cgtggaagag cggcaagaag atttgttgaa tcagtatgta
      721 tatacaattg atttattgtg gttaaatagt ggggaaacat ggaatagtga agaacttgca
      781 gcactatctg agaaagtatt agagaataat atttattttt ctatagaaga cgaacaaggc
      841 aacatggttt gggaacttac tggaaaagat ttgaagtcag cacaggagaa actgaaaaaa
      901 atgcattgaa agtttctgag aaaaacagtg tgaaactaga cgaaacaata gaagtgaaaa
      961 agaagttaat taatgatgga aacgagtttg gaaaagtaac gttttattat ttcggacctt
     1021 ttgcttatac agagcacgat gccttgttta tctccagtat gaaacaaagt ttaatgtatg
     1081 ttgcaattgc agctcttctt gtatcattca tacttgcttc gtggatctct gctagattag
     1141 gattgccact aaagcatgta agcgatttta cacataaatt aactcgtggg gaatatgctg
     1201 ataaaatccc acaagaaact tcaattattg aaataaattc cttaattgat tccctaaatg
     1261 atttaagtaa tcagttggag aaacagcatg ggcttcgaaa aagattaact accgatattt
     1321 cacatgaatt aagaactcca ttagctacgc ttaaaggcaa tgtggaagga atgattgacg
     1381 gagtctggaa aataactccc gagcgcctac aatcttgtta tgacgaaata gatcgtctaa
     1441 ctcgtttaat tggaaatata gaaataatca acaaaattga agcaaaatat gatcatttaa
     1501 ataaaactga gtttaacata tataagttga ttgaatccgt tattgaaaat ttcgccagca
     1561 aaattgagtc aaaaaacctt catgttgaaa tccaagggga taacatcaat atatctgcag
     1621 ataaagataa aatgaaccaa gttgttatca atcttttgaa taatgctatt aaatttacgc
     1681 aaaaggaggg aaccattaag ttttctataa gtaaaaataa agaccatgtt cttttaattg
     1741 ttgaagacaa cggcatcggt atagaaaaag atcagcaact tcatattttt gatagatttt
     1801 atatggctga cccctccaga agtagagctt taggggggca aggtatcgga ttagctattg
     1861 taaagagcgt tattgaagcg cataaaggta gtataactgt aaaaagtaaa ttaggtctag
     1921 gaactaaatt tgttataaag ttaccatttc aataaaggag gagagttatt tgtttcaaaa
     1981 acagataaaa attgctaaac tagtatgtga atgttgggca aaaaaaatat tttttcaact
     2041 gatttcgata gatagtgtcg aaaaagttca tttagatatc ttatcaaatt ctgtagtaat
     2101 cttttctaag aaggacttat caatagctac aattaaaaaa gaagtttttg gattacaaat
     2161 ttatgagatg acctaaatgt gattaattaa aggaggatga agacagtgaa aaagatgaca
     2221 aaattagtat ttgcaagtct tggaattatt gtatttttag gagcgtgtag caatcaaagt
     2281 gaatcgaata attctaatag cacaaacgag gaatcgactt ctacagcgtc tagtgaaatg
     2341 aatagtatgg agggaatgaa tcacgaaggt atggttcctt cttcaatgaa agatgctgcg
     2401 aaccctaaat tcccggtggg aagtaatgtt atactgctag gcgatcatat ggaagggatg
     2461 aaaggtgcaa atgctcaagt tgtaggggcc tttgatacta caatgtatga agtaagctat
     2521 gagccaaaaa ctgggggacc aatggttaac aatcatcgat gggtagtaca agaagagtta
     2581 aaagatactg agactgtagc aaatgagggc gatactgtta tcttgaatgc cgatcacatg
     2641 gatgggatga tgggagctga agcaaaagta gataaatcta ttacaggaac tgtttacgtt
     2701 gttaattaca ctccaaccga tggtcaagaa gaagttaaga atcatatgtg ggtaactgaa
     2761 gatgagatgg aatatgacga aaataatgag taattttata tactaaacca acaagctggt
     2821 acatggtctt cgtattctca acatgaggaa tatgagctct ttgttaataa ggactgatga
     2881 gttgtgcaaa atcaaatctg ggtcagaacg aacctcattc tggctcagat ttttggctct
     2941 tcgacattta gtgctggtag agagacaact gaaaatttag tcataaccag ttaggcagag
     3001 tgcttaactg gtttttgttc gcatttatta ttcttttgat attggctgct tgcccttcaa
     3061 ttttatttgg tttcttaatc aactcttcat ataaccccaa atcatatatt aatgaggtgc
     3121 ctcctattcc tataaatcta tctcttcttt aatagtatga gaaaagtcta ctcttgtaga
     3181 tttaaattgt caacaaaaaa tttacagatg taaatgataa gttgaataga gaaagataaa
     3241 ttattttttt ggtattcata taaggttaat tatgtattat cacaaaatga ttgttgtcga
     3301 ataactaaaa gtgtcaaaac aatgatgaaa tcatttagtt cttataaatt agacaagaga
//
LOCUS       DAMEEU010000140         3236 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.146, whole genome shotgun sequence.
ACCESSION   DAMEEU010000140 DAMEEU010000000
VERSION     DAMEEU010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.146"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            120..1754
                     /locus_tag="PB779_002807"
     CDS             120..1754
                     /locus_tag="PB779_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740287.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTFKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
     gene            complement(2021..3190)
                     /locus_tag="PB779_002808"
     CDS             complement(2021..3190)
                     /locus_tag="PB779_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HDE0740288.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
BASE COUNT         1065 a          463 c          496 g         1212 t
ORIGIN      
        1 aaacactact tttgtaatat aaaaaatatt ttattaataa taaaattaat cacattttat
       61 atagtgacta atctagtgtt taaaaaaaat aaatgatact atatgtaata taaaaaaaca
      121 tgaggtggta tatgaatttg aaaaaaattt tttctgtaaa aatatttata gtttatgcat
      181 ttgttagttt attatattta tttccagcat ttaaaaacat ggaaatattt ggcttttatg
      241 atacggcatt tcacattaat cgtgcgttaa gtttagaatc tatttttagc tcccctatta
      301 attttgaaac gtttagatca tatggcatgc aagtaaataa tttttaccca tggttaactc
      361 tatatccttt atttttattg atcaagttta ctaatttagc aataggctat aacctttttc
      421 tttatattgt tacgctcatt actctattta tatgtcatta tgtaatgtat gaaattacca
      481 aaaaacatgt tactagctcc tttttcgcta ttatatatac aacatcttct tttaggagtg
      541 tagaaatatt tcttcgaggg gcaatggggg aattactcgc aatgtcaata cttcctctta
      601 ttttactcgg gtttataaag ctttacgact caaaaaaaga atcttgggtt atgttggcga
      661 ttagcatgac tttattaatt tacactcatg ttctttctgt agctatgact atggtaatga
      721 ttataattgc tttaattatt caattttatc ggaaaaagaa aatagaaatc ttcttaatta
      781 ttaaattaat aaaagctgct atagttactt tacttctttc actagcgttt ataggtccta
      841 tgattgagca gacattgtat caagatctga atagacctta tgtggatata ttacaaaaaa
      901 gagcaattta tctgggtaaa gagtttttga ttggaagtat agattcagaa ttactatcat
      961 ttggtattgg cttaactttg cttatttgtt taattatact aacatttaac tttaaaaaat
     1021 taggaatctt atctaaaatc acttatataa tgggtataat atctattcta ctttgtacaa
     1081 aaatatttcc atggtttgcc ttacaaaata ctcctttaaa tattattcaa gctccttggc
     1141 gttttatgat attttcaaca ttgttcatat ctttttcagt atctctattt atttctccac
     1201 agttggaaaa attttcttat acaaggagaa gaaattttat actattatta atattagcta
     1261 tttcaatttt aaattattca tcagtagtta acatggtgaa agaaatgaat tttcaaggaa
     1321 cttattctaa tgaacaaatg gaaaataaac ttgaagaatt tgagaatttt gattatgtac
     1381 ctataggcta taaaaaagat caattgcttt tgaaaaacca tcaagttaca gaagatggtc
     1441 aagttattta tagtagcttt tctccaaata aagatgaaat tacatttacg tttaaatctt
     1501 caaaaggcaa aacaatagtt ttacctgtat tccggtataa aggattaacg gttactgtta
     1561 attcaaaaaa tgctacagta ctaaaacaag gaggtccttt tgttacagta aaaagtgaaa
     1621 gtggaataaa taaagtaaca atcaggtatt catacacatt tttttctaaa atctcattat
     1681 ttatttctat aatcacgcta attgttcttc ttttttattg cataaaatta aaaataagaa
     1741 caagccatga atgatttgct agcacatatt ttagcaatct aaagatacta ttttagattt
     1801 aataggccct ttgtcaaata atgttggtaa agagaaatct tagaataatt tggacagaac
     1861 agaaagaaga acacctcttt ctgttctgtt tatttggaat taaagtctgt agcaaaaatt
     1921 gatttttaga tttgtcccac actctttcct acgtttagtc gagtactttt tttaagcaaa
     1981 tgctattcaa agaagtagta tttgctatct tttcatcata tcagctattt gccaacttag
     2041 tagttccttc catcaggtca tagatttggt ttcttagatc agcagtaggc agtttgatag
     2101 ttttgtcagc ttttatattg ctttccatga tgatagcatc ctgtgaatct ttgctaaata
     2161 tagcagatgt atcaaaagag tcgatatttc cttgcgacag gatataatta tctccgctat
     2221 ataccccacc actatatgga tgtccattcg cattttcacg ccataatgag aagagtaagt
     2281 ctttggaaac tagttttcca gataaaactt gtgtaaacag cgtatttaaa tcatagacgg
     2341 acatactgat attaccagtc cctaattcgt tatggatctc tgtttcagat tctgtcagtg
     2401 gtttaaagta atcatcctct ttagacattt gataggatag tgcatgattg gatgaatttt
     2461 tgacttggtc ataaaatttt gtatgctgta atcctaaagg ttcgatgata tcatcggtca
     2521 ataatttttc atacggttga tttgttaatt tgatcaaaat tccagtcaat atggtaaagt
     2581 tcaatgaatc ataatgagag gtctgataat ctgtaaattt taagtgctga atcgcaaatt
     2641 gaacgacttc ttcatcagtc atcggtatgg ttggagaagc agttcggtgc aagcctgagc
     2701 gcatatacag caagtcacgg atagtaattt gctggctgcc agcaatttgt ggatagaatt
     2761 gagccagctt agtatctaaa gaaaggtgcc cacgctcgac ttgttttaaa atcaaaagag
     2821 tagtcaatgc tttttgaacc gaaccaatct gataataaag agaaggatca tttggttgtt
     2881 gcgtgagttt attcgcatag ccatagcctt tttccatgat gatgcgatta tttttcttta
     2941 cgtaaattga gccaatataa tcattttttc ttaatagttg atcgattttt tcaacgagct
     3001 gttgttcatt ggtagtcagt atcaactttt tttgagctga ttgagcatgg gcaactatct
     3061 gagagtgttc attattgtaa aattgccatc caagaatagt tcctgtagag aacgcactaa
     3121 ggctaaacaa cacgacaacg atcattaaaa atgaatattt tcttttttta gcatgttttc
     3181 cttttttcat aatagtttat ttagtctcct ttctttttta cagaaagaat aaagct
//
LOCUS       DAMEEU010000141         3186 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.147, whole genome shotgun sequence.
ACCESSION   DAMEEU010000141 DAMEEU010000000
VERSION     DAMEEU010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3186)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3186)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3186
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.147"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..750)
                     /locus_tag="PB779_002809"
     CDS             complement(<1..750)
                     /locus_tag="PB779_002809"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HDE0740289.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSL"
     gene            complement(765..1592)
                     /gene="panB"
                     /locus_tag="PB779_002810"
     CDS             complement(765..1592)
                     /gene="panB"
                     /locus_tag="PB779_002810"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HDE0740290.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            complement(1604..2464)
                     /locus_tag="PB779_002811"
     CDS             complement(1604..2464)
                     /locus_tag="PB779_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HDE0740291.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            2702..>3186
                     /locus_tag="PB779_002812"
     CDS             2702..>3186
                     /locus_tag="PB779_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDE0740292.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     F"
BASE COUNT         1033 a          610 c          374 g         1169 t
ORIGIN      
        1 taatgataaa gaatcaacaa cttctacata atcaatcttt gccaaattat aagtatttat
       61 atttttactt attatctcaa ttatttttaa gctgtctctc tctccattat ttaaagcttc
      121 cttagctaaa gttaaagatt tatttaaaat agtagctgaa gatctttcct ctaaacttaa
      181 gtatgtgttt ctagaacttt tagctagtcc atcctcttcc cttataattg gacaccctac
      241 aacgtctata tcaatattaa ggtccctaac cattctttta attacagcta actgttgtgc
      301 atccttttct ccaaaataag ctctatctgc tggtattatg ttaaataatt tacttacaac
      361 agtgcaaacc cctctaaaat gtattggcct actagctcca cataaacctt ctgttaatcc
      421 agttatatta acaaaagtac ttgcattgtc acaatacatc tcttcaactt caggattaaa
      481 tattgctgtt gctctacctc ttgtgcatac ttctatatct ctttctaagt ctcttggata
      541 actacctaaa tcttcatttt tcccaaactg agttggattt acaaagatac ttacaacaac
      601 tttatcattt tcttttgatg cttttctaat taaactttca tgaccttcat gtaaatatcc
      661 catagtagga actaatccta cctttaagcc ttgttttttc cactctttta cttgacttct
      721 aacatcattc actgttttaa atataaccat atttcttgac ccttttaata taatttttct
      781 aaaacatcat cacttatttt aaacccatgt tctggacctg gaaaaactcc atcttttact
      841 tcctctatat attttgtaaa tgctttattc atctcttctg ataaattagc atatttcttc
      901 acaaatttag gggtaaaatc actatacatc cccaacatat cttgatatac aagaatttgt
      961 ccatcacacc ctgcacctgc tccaatacca attgtaggta ttgatatctc tttagaaatt
     1021 aactctgcaa gcttagttgg aacacattct aacactacag cgaatgctcc tgctttttct
     1081 acagctttag cagctcttat taattcttta gcagcttcct tgtcctttcc ttgtacctta
     1141 aatcctccaa atgcattaac agattgaggt gttaaaccta tatgcgccat aacaggtata
     1201 gaagccttta ctatagcctc tattttatcg catacttcta tccctccttc taatttaaca
     1261 acctgagctc gtccttcttt tattaatctt cctgcattaa ctactgaatc atatactgaa
     1321 gtttgataag acataaatgg catatctgca acaactaaag tgttcttagc tcctcttgta
     1381 actgctctag tatgatgaat catgtcttcc attgttactg aaagtgtatc ttcatgtcct
     1441 agacatacca taccaagaga atctcctact aatattccat ttatcccagc ttcatcaatt
     1501 atttttgctg ttgaatagtc ataagctgta agcattgtta atttttcatt tcttaattta
     1561 gattctttaa atgtaactgc tgtatttttc atctatttct ctcctaactc tctcctaaat
     1621 acttttctaa ttcactataa tctctattaa tattttttaa catagctatc tctaatacat
     1681 tttttgataa tagcatatat aaagctctgt cttcatctga taaaacttca cagtgacctt
     1741 taattgttga aatatcacaa cgttcaactg gccctgtcaa actttctata attccttttt
     1801 cttttatatt tctaatatta aattcaatta atggatataa agcttcaatt gccatttttt
     1861 cagtaaatcc acattgaatt agatatgtaa cgcttgtatt aataagtcct agcacaaggt
     1921 tactagatac tactgatgcg gcatgataaa gagatttatt ctccttagat acaattacag
     1981 tactattacc taactttttg aagaaatcac ataaaaactt tgcatatttt tcatcgcctt
     2041 caattgttat aaaagatttt tttaattttt tgtatgaatt atatttatct gatattgaaa
     2101 acataggatg gacagaatag ccataagcac catagtcctg tatatttgaa aagatatctg
     2161 aagatattgc accactgcaa tggcagatta atttgttttt gatttgataa tttttaattt
     2221 cttgccatac ctcctgaatt tgaccatcag gagtcgtaat gaaaatagta tcattttcat
     2281 ctactaattc tcttaagttt aaatattgtt tactagatgt aaaattcgaa gctgctaatg
     2341 acgagtcttc gcttttacta taaaatcctg ttacttgtat tttatgttcc tggaaatact
     2401 tcccgaatga acaacctacc ttgccggctc caataaaacc aacgttcata attatcacct
     2461 ccataaagaa gtgagactac aagtcccatt cttacgatat gagcttaaaa ataaaaatta
     2521 aatcaaatat acagtatgtt tttttcaaat atcatccata gttaatttat cataatatcc
     2581 catattttaa aataaaagat agcgtaaaat attttgtgta aatagaaatt tagggtagaa
     2641 aaaaaagtcc attctgtaaa attaaagtta ccacacagaa attttatagg aggactttct
     2701 catgactaaa tttactatag aaattatgca aacactactc aataaagggg atttagatga
     2761 attatttcag gatcatttag agcgagcgat taattcactt ctacaagcag agctaactgc
     2821 ttttttagat tacgaaaaat atgatcgaaa tggattcaat tcaggaaatt cccgtaacgg
     2881 gaattattca cgtacattta aaacagaata tggcgagttg aatttaacta ttcctagaga
     2941 tcggaatggc gaattttctc aacaaacact accagcatat aagcgaacca atgattcatt
     3001 agaaacgacc attatccaat tatttcaaaa aggcattact atggctgaaa tctccaaatt
     3061 aattgaaaaa atgtatggtc accactatac gccacaaaca atctccaaca tgagtaaatt
     3121 ggtggctgaa gatgttttag cttttaaaga aagaacgtta gaagccaatt attccgttat
     3181 atttat
//
LOCUS       DAMEEU010000142         3101 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.148, whole genome shotgun sequence.
ACCESSION   DAMEEU010000142 DAMEEU010000000
VERSION     DAMEEU010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.148"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            598..684
                     /locus_tag="PB779_002813"
                     /pseudo
     CDS             598..684
                     /locus_tag="PB779_002813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            1244..1462
                     /locus_tag="PB779_002814"
                     /pseudo
     CDS             1244..1462
                     /locus_tag="PB779_002814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            1722..1976
                     /locus_tag="PB779_002815"
     CDS             1722..1976
                     /locus_tag="PB779_002815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HDE0740293.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDTIQAKQEGNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            1977..2294
                     /locus_tag="PB779_002816"
     CDS             1977..2294
                     /locus_tag="PB779_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HDE0740294.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
     gene            2853..>3101
                     /locus_tag="PB779_002817"
     CDS             2853..>3101
                     /locus_tag="PB779_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740295.1"
                     /translation="MNILNEKRYVWFAGKKYITTFKRLSELMQQTVKSAMPEGYKFNF
                     VQSSVSTESIYFSILSESRLFHFRISSHVKKTDVDIYTF"
BASE COUNT         1110 a          426 c          531 g         1034 t
ORIGIN      
        1 taatacttaa attagatact acctatattt atattaagta ctaccgttct aggaataaga
       61 taataaaaaa aaactaccaa attgcaatta aatactactt aaaatgtaaa aaataagaac
      121 tacccaaatt aggtagttct taataagaga atatcagata aatttgtaca agtcataaaa
      181 aaattaatct taaattttta aatatatata cctgttaatt ataaactact ttatttaggt
      241 agtacataat taacagataa aactacatgc ttgtagtttg tctagctaat gagttgcata
      301 tgatttatat aaaggtgtgc agcataactt agttgaagtt aagagaatag aataaatatt
      361 ttttgttttg ctaataatta aacactacct aaatatggta gtgtttaatt atataatatt
      421 cattttgtta caaataatcg tattataaaa gcataacaat tgggataact attttttaga
      481 ttatttaagt actacttaaa ttaggtagta cttaaatttt ggtttaaggt agtaggtaat
      541 taagaaataa tatatatctt cttttataat agaaggggag aggcctagtt aaaaacagcg
      601 acaattaata acaatgtatt taatgcttca caaaatccat ttggtggaca atgcattgtt
      661 attagcgatg atctaccgtt ctaagtagtt ttttctattg gttgcattcg tgactaatta
      721 tggtataatt atgagtaaca aagaggtatt tcattatatc atcaaacccc atcagcgtgt
      781 aggctgatgg ggtttttttt acgtttctat attatagaat taactggtag gcttactgtc
      841 ttttttggca attttgcaat caagccactt gcagatgtag tgtgcagtta cctctgcaaa
      901 tggcttgatt gcaaaaacaa aatcaaaaag gtatttcatt atatctcctc ctccccttgc
      961 cagattaggc cggggtagca gacagcaaaa ctattataac ataactgaaa tacctaaatg
     1021 acatatacag atatgataat ttatgtattg atttttctaa caaaagcaca tattttaata
     1081 tatactacct attttaggta gtatatattt ttagatacaa tatcgatcag ttttgaggaa
     1141 atgaaattct agatattttt tgctacatag agttactttc aatatttttt aacgtaatta
     1201 ggcagaagtc actcatcctc tataggtttg tgatgaaatt gctattgatc catttaagta
     1261 agagcaaaaa actggaggtt tatcaggtaa ttggtctaat ggatttaagt atgcggtcac
     1321 cgtgtataga gttgcttatg agattcaaga aaataaagtt attccagtat tgctatatgg
     1381 aacacataac aatttttatg aattagccga gaacactcgc aactttattc gtgtagatga
     1441 atcggcttcg gttgagttat aactttagct atatcaatca accgaccgac atatgttaaa
     1501 tctatatata ataaaaatac ctacttaaat ggatgttaac ggaagtgtat ggtgagtagt
     1561 tcactcgtat tttgatatcg tttgtatatg ttttcagcgt tctaagtggc ttattttgtc
     1621 caataataat atggagtgga atcccttaag aaacaccgtt ggcaattgtc gttataacat
     1681 gttataattt atttatcaaa aactaaaaga agtgtgataa catgggaaaa gaactaaagg
     1741 ttagaaagat cggcaatagc gtgggagtga tccttccaag ctctcttgga ttaaaaagcg
     1801 gagacactat ccaagccaaa caagaaggca acttattcat attagatact actcaaatag
     1861 caaaagaaca cgatcgcaaa ttgattgaag aaagtttcca agactttgag aaaggtttaa
     1921 cagtttcaga aattgaaatg gtaaaagctt tcggaaaata cggctggagt gaatagatga
     1981 aagagtacac gctagtttat tctaaaagtt tccagaccag ccttgaaacg ataatagaag
     2041 aatgggaaaa tgagcttgct ctttctccag ccagcataaa aagatttgta ggtgcgatcc
     2101 agaaggcttt agaactaacc aaaaattttc caactatgca tgaggaagtt tccgaaatct
     2161 atggaatgga tatcccaaca tatcggatcg tgatcggcaa aagctatgcc ttattttatc
     2221 ggatcgacca tgaaaaaaaa gagatacttg taggacgtat tttccaatct aaacaaatga
     2281 aactaggctt ttaacaataa ttaggcaaaa gtcgctcatc ctctacaggt gggtgattaa
     2341 tgccgctcga tatggttgtt aaccgtcggt tactcgaaga ttgatatata agacttagta
     2401 cctttttatt ttgctccatg ttatggccga aggtctaaag atacaatcat tagtctagag
     2461 aaaaattaag aaccgtagga actacgggga tcgcttggtg aataagagac actgctatta
     2521 gtgaaaaaat aagatatcaa gtacgctcta ttcccaaaaa tttcgtgact ttactcatga
     2581 gaggttcaag tagtatattt ttaatcaaaa ttgacgtaac ttttaataaa tactacctaa
     2641 ataaggtagt atttattttt gtgttttaaa agaggaagtc caatatatct atgggaaact
     2701 tcttaaatat tatgttggta catgaaaata tacatccctg ctagactatt tacaacattt
     2761 tactttgtac gtattcttgt tttaaaagga atgggataaa atataggtac aataactatt
     2821 tgatgctaaa tataattaat ggaggagaga tagtgaacat acttaatgaa aaaagatatg
     2881 tatggtttgc tggtaaaaaa tatattacta ctttcaaaag attatccgag ttaatgcagc
     2941 agactgttaa aagtgctatg cctgaaggat acaagtttaa ttttgttcaa tcttcagtat
     3001 ctactgaaag tatctatttt tcaattcttt ctgagagtag gctttttcat tttagaataa
     3061 gttctcatgt aaagaaaact gatgttgata tatatacgtt c
//
LOCUS       DAMEEU010000143         3027 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.149, whole genome shotgun sequence.
ACCESSION   DAMEEU010000143 DAMEEU010000000
VERSION     DAMEEU010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 3027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.149"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(276..692)
                     /locus_tag="PB779_002818"
     CDS             complement(276..692)
                     /locus_tag="PB779_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001232859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740296.1"
                     /translation="MRKTSVQKHVTLYPSHVDVLDSIIEKNPDINNYSEAIRFLCMSY
                     EPDTNTTTTSNQAKLNAMGKEISIMTEIIAEFADLYLKDTGVLIGTNSKVYQEVKEKI
                     EAKLNPSNRNRPKNHQKETSQTVTSRNFDPTNFLKR"
     gene            complement(695..979)
                     /locus_tag="PB779_002819"
     CDS             complement(695..979)
                     /locus_tag="PB779_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740297.1"
                     /translation="MDILVRNIDPKFVATIDKRCQELTNKTGEKWSRNKYLKVLIESD
                     FDRQLTTYKKDQFDLLLDKFIAIQTENTQILSEYVYTNNQIIEMLIGGMI"
     gene            complement(1679..1774)
                     /locus_tag="PB779_002820"
     CDS             complement(1679..1774)
                     /locus_tag="PB779_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HDE0740298.1"
                     /translation="MCFVFTNFICSLLVGLLSALFSYWLNNRNKK"
     gene            2447..>3027
                     /locus_tag="PB779_002821"
     CDS             2447..>3027
                     /locus_tag="PB779_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDE0740299.1"
                     /translation="MDEKTELTVKYQNELNLVPLKNFNAKQMDLFFALCARMKDRGLK
                     KVRFSFEELKELSDYKMTATKAFVGDLEKLYKDMLNLTYRTEDEDSIRYFVLFTGFEI
                     NKTKKFVEVSVNPDLEYIINGLTAEFSRFELSAFTSLRSTYAKTLFRLLMQYRSTGYY
                     VVRIEEFRSLMDIPEYYQMGNIDQKVLNPALREL"
BASE COUNT          964 a          481 c          566 g         1016 t
ORIGIN      
        1 aaaaaaatac ttcaatgatc ttaaagtcac aaaaataaaa gcaaaaaagg gcaataaaat
       61 cgccaaatta gaatttactt tttcaagcct aacgtcagat ttgccaaaga tttctctgcg
      121 taactggtta gaagaataaa taaaaaagaa ctcgcccccc ttacattaag caagtagaca
      181 agtcccttac aaccgactaa gattgctagt acattctagc atattgtatg gggcttctaa
      241 ataaaaaaca gataggaata actcctatct gttttttatc gttttagaaa atttgttggg
      301 tcgaaatttc tagaagtgac tgtttgactg gtttcttttt gatgattctt tggtcgattt
      361 cgatttgatg gatttagttt agcttcgatt ttttctttca cttcttgata tactttagaa
      421 tttgtgccaa taagaacgcc tgtatctttt agatataaat cagcaaattc tgcgatgatt
      481 tcagtcatga tggaaatttc ttttcccata gcatttagtt ttgcctgatt gctggtagtg
      541 gtcgtgttgg tatcgggttc ataactcata cataaaaagc gaatggcttc cgagtagtta
      601 ttgatatctg gatttttttc gatgatggaa tctaaaacgt caacatgact agggtacaaa
      661 gtaacatgtt tttggacaga agtttttctc atggttatat cattcctccg ataagcattt
      721 caatgatttg attatttgtg tagacatact cgcttaatat ttgagtattt tctgtttgga
      781 tagcaataaa tttatcgagc aataaatcga attggtcttt tttgtaagtc gtaagttgac
      841 ggtcaaaatc actttcgatt aaaactttta gatatttatt tcgactccat ttttctcctg
      901 ttttattcgt gagttcttgg caacgtttgt ctattgttgc aacaaacttt ggatcaatat
      961 tccgaactaa aatgtccata aaaaatctcc ttttgcaatt atgtataatt tatgtatacc
     1021 atacaaatac tatatttgta tagctgtttt ttgccaaaat gctatacata agctacccac
     1081 gatggcgaaa aagtgatatc aaattttttt ctgagaaacg tgataggcac agcctatcta
     1141 cccacttttt ttagaaagtg ggtacacgtt tccttatgct ctttaaaatt cgggggggag
     1201 tgctgcacgt gtaatcgata accaaattta acagacgaaa aattgttgga atataaaaat
     1261 atgacacccg aaagaaaacg atcgttggaa aaattaatgc aactagtgaa cgaagacggc
     1321 ggaatttcag acgcagcttt tgacgcatgg agcgaatttc atggagaata taattaagtg
     1381 ggtttaaatg gctctaaaat cgcttctaag agttttttag cttggaccaa tgaaatacac
     1441 caaaaactaa ataaaacgtc ttaaatcgaa aaatacgagc tctcagagcg actttatttg
     1501 taaatgttgc atataagaaa taattacgga ttttagactt ttgtaggata tttttgaaat
     1561 aaatatttat ttctgttata atttgattgc aaataagtga acacgaaaca cacgaaatcc
     1621 ccagagaggt cggattctct ggggcttttt ttgtgggctg agtcgcctta attaagtttt
     1681 acttcttgtt tcggttattc aaccagtaac tgaacaaagc gcttaaaagc ccaacaagaa
     1741 gggagcaaat aaagttagtg aacacgaaac acacctcctt ccagtcgcaa gactgtcgga
     1801 taggcgacaa tcaattatac aataaaaaag caaaaataag cctaagtttt ttattgcctt
     1861 ggggttgtta gggcttgccc tgaccgcctg taaggcgctt tagaacgaag gacatagttt
     1921 ttatcgaatc ttgtcttaga acggcttaga cgagctctca ggacgccaca aaggagtccc
     1981 taatgaatta tttttggcga aggagcctaa aggcgactgc tgcaagtaaa atgtgagagc
     2041 gtagcgatca ctccttctta cagcgaccat agggagctag attggcagtt taatatcatg
     2101 cgcgaacctg tttattttaa aaagtgggtg attttttggc gggaaatttt gctcgcgcgc
     2161 gcgtttattt tatttatttt ttaaagattt tttagaaccc tttttagggg gcagttgagc
     2221 cttactctcc caacggatac agaagggtac taacaacttt ttatctgagt actaacaact
     2281 ttttatctga gtactaacaa ctttttatct gagtactaac aactttttat ctgagtacta
     2341 acaacttttt atctgagtac taatatcctt ttgtataata acaaccaacc tatttacgag
     2401 ttggttgtta aaggttatta tttatttgta aggggggaag aaaggaatgg atgaaaaaac
     2461 ggaattaaca gtcaaatatc aaaatgaatt gaatttagta ccgctgaaaa atttcaatgc
     2521 taagcagatg gatttatttt ttgcattatg cgctcgtatg aaagatcgtg gtttgaaaaa
     2581 agttagattt tctttcgagg aattaaaaga gttaagtgat tataagatga ctgctacaaa
     2641 agcctttgtc ggtgatttag aaaagctcta taaagatatg cttaatctta cttaccgtac
     2701 tgaagatgag gattctattc gctactttgt tttgtttact ggttttgaaa tcaataaaac
     2761 aaaaaagttt gttgaagtca gtgttaatcc ggacctagaa tatattatta atggtttaac
     2821 agctgaattt agtagatttg aattatctgc tttcacgtcg ttgcgttcta cgtatgcaaa
     2881 aactctattc cgactgctta tgcagtaccg ttctactggt tattatgtag ttcgtattga
     2941 agagtttagg agcttaatgg atatcccaga atactatcaa atgggtaaca ttgatcaaaa
     3001 agtattaaat cctgcattac gagaact
//
LOCUS       DAMEEU010000144         2952 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.150, whole genome shotgun sequence.
ACCESSION   DAMEEU010000144 DAMEEU010000000
VERSION     DAMEEU010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2952)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2952)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2952
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.150"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            89..406
                     /locus_tag="PB779_002822"
     CDS             89..406
                     /locus_tag="PB779_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HDE0740300.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(497..862)
                     /locus_tag="PB779_002823"
     CDS             complement(497..862)
                     /locus_tag="PB779_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740301.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1070..1552
                     /locus_tag="PB779_002824"
     CDS             1070..1552
                     /locus_tag="PB779_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740302.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSTFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            1749..2639
                     /locus_tag="PB779_002825"
     CDS             1749..2639
                     /locus_tag="PB779_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HDE0740303.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
BASE COUNT         1008 a          460 c          566 g          918 t
ORIGIN      
        1 ttttaaaaca tcacaaggaa aaacttaact atggtattat ctaaacataa ttttttcggt
       61 atttaatatt taattaggag gtaatatttt gcttttttat agtaatttta tcttaatagt
      121 agcgatatta ttacttctga atatatggat ttttgatagg agtagaaatt caagtatagg
      181 ttttagaact aaacgaagtt tgtcttctaa aaaaaattgg gtatactcac aaactatttt
      241 ttatggagga attgttttaa ttagtttact ttcttcaaca ctttattctt tgaatattat
      301 agatgtttcc acctcaaatt caatatctat tattggaatc attattgctg caattattac
      361 acaactgttt ttagtgtttg gagagaagaa aagaagtaaa aaatagaaaa actagtgata
      421 gttttggtga tataagaaaa acatatatgt ataaaaagaa gaaagtagct tctctttgta
      481 catatatggt ttgtttttat ggatgccgag cttttttata agataaggct accgcccata
      541 acgacccaag gatttgtgga actaagtaaa tacctgcaag aagcaagatc agctgggtcg
      601 gttttaaagg atgatagaag taacgccatt cagtaaaatt ggcgcaaaat aaataggaag
      661 tgacagtaga tataatattg gcaatgaata aagatataat acgcctgttc ctttgaaaat
      721 aatatccagc aaaaagagat aaaaatatca atgtgatgaa cccgcttacg gaatgataac
      781 gaaaatcaag cagtaaggcg aaatgcacat aaggaacaaa agataaaagc aacggaaggt
      841 ttttccagca agtttttatc atctttcatc accacctaac aagtgttatt attttgttag
      901 ttttattgta aattgaatcc tgcaataatc aattactttt tcattatttc tagattaaat
      961 gaataaactc tcatgccatt atctctaaaa aaaaagtttt tccccctaat ttttttagat
     1021 agaaaattgt atagtatgat gagagaaaaa gtagtttggg ggaacgttaa tgagaagaaa
     1081 agcagtaatc gatcggcttt atttattttt ttggtttttt cctatcgttt tgctaccttt
     1141 tacatgggta aatgctgttg tacaaggtgc ggagatatta ggcctgatcc aaggaagcgg
     1201 atttgtggtt tctaggaatt ttccagcttt gattgttttc tatttagtga taagtgtagg
     1261 tctcttatta ccaaaatctc tgatcaatca ctacaattgg cagctgcttt acttttcttg
     1321 cttattagta tttacatcta cgttttcttt gctgcctcgc ttgattatcg gccctaatgg
     1381 tttgagcgag agtggattga aggatttagc ttattcctcc atgtatttct tgacgatcaa
     1441 accatggttc tatttagtaa ttgcctcatt tattcttgca acattttttt acttctggac
     1501 agaaatcagg ataaaaagtg aacgatctgt atctataaaa aataactatt gatggtggat
     1561 catcagtaaa aaaacatatg agctgcgtaa aatgcatgtt tctcatatgc tttttttatt
     1621 attatgtaaa gaatgcgaaa aacgtttaca tgatttttac ataacttaac tatattttta
     1681 cagcaaccat acgagggatt tacagtcgac tgataaactt tagttgtaaa taagaaagga
     1741 gcaataaaat gaaaaaagta ttgtttactc taggtatgat gggaattctt ttagccggat
     1801 gcggctcagg atcaggaaat acagatggct ctgccacaca aaataattca agtgactcaa
     1861 atgaacaagt aaaaatcgtt gcggtaggtt cgacagcatt acagccgtta gtcgatgcag
     1921 cacaagaaag ctttgtacaa gaaaatccaa attatcaaat ctctgtacaa ggaggaggaa
     1981 gcggaactgg tttgagccaa gtcgaagctg gagcagttac tatcggaaac tctgatgtat
     2041 ttgcagaaga aagagacgga gttgatgctt caaaattagt ggatcataaa gtagcagtgg
     2101 tcgggatggc accaatcgtc aataaagata cagatgtcaa agatatcacc aaacaggaat
     2161 tgattgatat ctttacagga aaaatcacta actggaagga agttggcggg aaagatcaaa
     2221 aaatcaacgt cgtgaaccgt gcaaacggca gcggtacccg cgcgacattc gaaaaatggg
     2281 gactggatgg tgctacccct gtgcagtccc aagaacaaga ttcatcagga acagttcggc
     2341 agctggtaag tcaaacacca ggagcaatca gctatttagc tttctcatat ctcgatgatt
     2401 ccacacaagc actaagtatc gacggtgtag aaccaaaaga agagaatgta gcagataaca
     2461 gctggggaat ctggtcatat gaacatatgt acacgaacgg aaaaccttcc cctgaagtcc
     2521 aaaaattctt agactacatg atgacagaag aaatccaaga aggacctgtc aaagaattgg
     2581 gctatttacc aatcacaatg atggaagtag aacgtgatca cgaaggaaat atcaaataac
     2641 tagcagataa acatgccacg gtagtcgtta ctattaagga aaaatcaact atgtttcccc
     2701 acatatacat ttttccttta attgtgaaaa atagttcctc atattttgcc gttttttgag
     2761 ctaataccga gggtcagctg attgaacacc gtttattcga aaaaaagagc tacgacatag
     2821 aactgtcgta actttttttg gctcttcgtc aaatcgtgtt ggtgaagaca aatttgaata
     2881 aaacttagac cgatatgcgg cgcgttctgt gcgccgcata tttttttagt tttcaaagat
     2941 cagaccttgt tg
//
LOCUS       DAMEEU010000145         2778 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.151, whole genome shotgun sequence.
ACCESSION   DAMEEU010000145 DAMEEU010000000
VERSION     DAMEEU010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.151"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            143..466
                     /locus_tag="PB779_002826"
     CDS             143..466
                     /locus_tag="PB779_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740304.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            630..884
                     /locus_tag="PB779_002827"
     CDS             630..884
                     /locus_tag="PB779_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740305.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            954..1199
                     /locus_tag="PB779_002828"
     CDS             954..1199
                     /locus_tag="PB779_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740306.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            1275..1640
                     /locus_tag="PB779_002829"
     CDS             1275..1640
                     /locus_tag="PB779_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740307.1"
                     /translation="MRLWHEKLISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFH
                     YSPYRLFQYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHD
                     EVYLAECLANLEQKGIYLT"
     gene            complement(1701..2264)
                     /locus_tag="PB779_002830"
     CDS             complement(1701..2264)
                     /locus_tag="PB779_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740308.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
BASE COUNT          819 a          486 c          429 g         1044 t
ORIGIN      
        1 aatgacaaac tctcacaagt ttcaaaatat aagtaaaata atattgttat tcttatttct
       61 tttacttgtg tcataactat tttgttactt taatttttat ttgcttattt tagaaaaaat
      121 gttattcttt tatttattct caatgttagg agtgattatt ttgccattta ttgcgatttt
      181 attcgattta gttgcggcag cagcttattt tctccaatta aattatcaaa cctcaggaat
      241 tctgtttatt ggaatgattt ttcaaggtgt gattaccctt ttgcttcttg tcatgatgct
      301 cagctataaa ggaaaaagat atgcccgtat tcaaacaaaa gtatttgtta aatatgtttc
      361 cattcgctat gggatcatca ttctttcctt tttagtgaat gcgatcgtcc tctttttata
      421 tgtattgaat tacttagata tcaatccatt gattttttct cgatagataa gacacattca
      481 gcggaacagt tcctgcttat cagcagaaaa ctgttctgct ttttcatttt tcattgatct
      541 attcttcttt tattttccta gcatttcatt tgtgatgtat gcaataacat gttatctttt
      601 attatatgaa tcgttgagga gtccgttaca tgattacgtt ggtgagagtt ttgttttggg
      661 tgcctgcggt cgcactggtc gcaagtattg tttatcttat gaattggaac aaagaacggt
      721 tttatttagc tattttgact cttccggcta tctactttat gtggaaagtt tttaattaca
      781 actactttga acccgatagt gtttttatag aagaattatc aggactggtt ttgtctttat
      841 tgatcgtcat tctttatttg atacgtttaa ataaaaaaca ttgagtacta ttgattgcat
      901 gtgtagcttt ctatagtcat tataactatt ctactataat gaaaggtgat taaatgagta
      961 tcgaagaagc tattttactg gatactttac gttgtcgtct gaatttctta agaactggcc
     1021 gatctttatc tcaagtagct gtttctagcg cgttaagtat tcctttattc aaatatcgta
     1081 agtacgaaga aggagaagaa attccaagca tcattgaatt aatctatatc gctgactttt
     1141 acgatatttc cgttgattac ctaattggtc gctcagaaac agcaagcaaa ctgaagtgat
     1201 tttttccagc cttggtgctg gttttttcat ttaacgtcta aggttaacaa tctatatata
     1261 aaggagacat ttctatgcga ttatggcatg aaaaattgat ttcaaagctt cctcgtcaac
     1321 agcttttagg acaacatcgg gaatgctgtg cattaagagg aaatggctgg ggaaagaaac
     1381 atgctactgt ggattatgtt tttcactatt ctccttatag attattccaa tatcatcagc
     1441 ttgtcatgga tgaaatggaa aaacgtggtt acagcccagc accagagtgg aaaaatccta
     1501 tgtatcgtgg caaatcatgc gaagcatttt ttgatttacc tactgtagag cgcaacgtgc
     1561 cgatttatcc ggaacacgat gaagtttatc tagcagaatg tttagcaaat ttggagcaaa
     1621 aaggaattta tcttacctaa tataactaga aaagccttct atctcctctt acttcattaa
     1681 aaagctttaa ccatcttaga tcaagctaaa atgtcgtaag ttttagggtt atcttcatcc
     1741 tcacgtgcaa aactaaaagc gtactctagt tttggttcat cgccaacttc cctagacata
     1801 aatgaacatc tcctgacgtg gtttaaaagt accgcatctt cgacgtctgt atacgatgca
     1861 cagcacagat tgcttctttt gatctttctt ttgatttttc tgttgcttct tctacacctt
     1921 cttcgattac tacatcgatg cttacaattg cttctgccta atattcccat gcatcgtcga
     1981 tttaagcctc tgtagtcact gtgatcgttt ccacatttta actcctctgt cgtggcttca
     2041 gttgattttg tgatcagttc agttgctaag ccagagtcag aacaacctgc cattgctagc
     2101 gttaatattg atagtaaaaa tagttttttt atcataaggt tccccccctg aaaatagact
     2161 aaaataataa cgctttcttt ttttgttttc agacgaaaat taataatttc taaatattct
     2221 ttaaaaaagc ttataactat tatgcctttt ttaatatata acacagttat ttttaaaaat
     2281 aagaatgcta aatcactcta caataacggc gaaagcacaa aaaataaaaa aattattacg
     2341 ttattaaaaa aacagatgaa agatcaggtt ttattagatc tcattctttc atcacttgaa
     2401 gggatttaat gaactacttt ttcctctttg tcgtttttat atattcgtat tccttcaaac
     2461 agtaggatag cctctttcaa tgcttgatat ttgaactgtc cgttacttaa aaatttagat
     2521 gtgccgccct cttcctagaa catattcttt tttacttttt cattaattga cagaccaatc
     2581 gaacgaaact gtaaatttcg ataggataat gattggtcaa actcattcat tttcaagaca
     2641 tctcgattca tattcaagat aggaatcttt ttatcaacat cactttattc gtattttcct
     2701 ctaccataaa agcttcacgc tccacaaaat tgttttatac actactattc agcccattca
     2761 acgaccaatg aatttttt
//
LOCUS       DAMEEU010000146         2616 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.152, whole genome shotgun sequence.
ACCESSION   DAMEEU010000146 DAMEEU010000000
VERSION     DAMEEU010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.152"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(491..1783)
                     /locus_tag="PB779_002831"
     CDS             complement(491..1783)
                     /locus_tag="PB779_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HDE0740309.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVDVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2057..2317)
                     /locus_tag="PB779_002832"
     CDS             complement(2057..2317)
                     /locus_tag="PB779_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740310.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          886 a          483 c          398 g          849 t
ORIGIN      
        1 atattataaa ttcacatgat tatcgaattt tattaagtta gtttttcttg taaatctctg
       61 ttcccaatga aactcgagac acttatttta aagaggaaac aatgtggtat ttaaatagcc
      121 ctcttgtatg ggctactctg tgatacttat tagccattaa actattttac ccacatagca
      181 tatattttga aatcgttcat tccgtaaatt caactaaata tgcctaaaaa aataaaaaat
      241 ctaagataga ataagattta ttcagtctta gatggattta tagcaacttt ttcgtaacaa
      301 ctttaaaaaa tacgaaaaga aagagctgtt ttactctgac tacgttgcta aattgtcgtt
      361 taatcattca tttaaaccaa atcttttttt atagaattcg ttttaatcct cctgaatcca
      421 aaaactatga aaaccgtaat taaatagtta agagttttta accaccataa ttctctcggc
      481 tattttgaaa tcagataaat tttgatcgga cacatagttg aataaaccta ccgttgttac
      541 ggaaggtaaa tcgcatactt ttcattctag aggagaaggt ctcgttgatc attaactgat
      601 taagcaccat agcccagttt tgaattcgac cacctgacca cttcgcgtgt aattctttcg
      661 tgcgtaaata aagtagtttt aggagtgcat tctcattaga gaacgctcct ttttttgtga
      721 cttttctgaa gctggagtgg acactttcaa ccgcattggt agtgtacata atttttcgaa
      781 tggcactacc ataatcaaat agttgttcaa catgtgcaaa gttccgtttc cagacatcta
      841 cagcaccaga ataatgagac caccgatttt gaaaactgtc aaaagcagca tgtgcagcgt
      901 ttagagaaga agcaccgtag aactttttca tatctcggca gacttcctta tagtccttac
      961 ttggaatata gcgcaatgca tttcgaacaa gatgaacaat acagcgctga acaattaccg
     1021 atggaaagat cgcttttgcg ccttcttcga ggccagaaac accgtccatc gaaatgaaaa
     1081 agacatcttc gacaccacgt gctttcagtt catcaaatac ttgcatccag cgatttttag
     1141 attctgtttg atttaaccat aatcctaaaa tctccttatt tcctttgaga tcatagccaa
     1201 gaatggtgta tacagcatat tctttggctt cataattttc tcgtaaagta acatacatac
     1261 aatcaacgaa tagaaaggca taacactttg ctagggggcg ggcttgccat tcttccaatt
     1321 caggaaggac agcgtcagtg atatctgaaa tcatttcatg ggaaatatca aagccataaa
     1381 tagcttcgac ggttgcggca atatctcgtt gactcattcc tcgtgcatac atggaaagaa
     1441 ccttcccttc gatgtcggag acatctcgtt ttctcttagg aattaactct ggttcaaagg
     1501 aagcttcccg gtctctagga acatcaatag ctacttcacc aaaactggtt ttaagcgttt
     1561 tagttccata gccatttcga cggttatcgt gttccttagg ctctttagaa tgggcatcat
     1621 aacctaaatg attattcaat tctccttgaa gcattttttc aaaaaggggc ccaaacacat
     1681 ctttcaaagc atcttgcatg tcatcgacag attcaggttg ataggcattc agaatggatt
     1741 cagctaactt ttcggcatca ggatttcttt tctttctagc catcgtgtaa tcacctcttg
     1801 atcttattgt agaaaaagaa aaaccgcgaa gcaaccacct gcctaggatt aatggttact
     1861 tacacggttt atattacact ctcatcatta aaaaagtatc tttcgatatt actaaacaat
     1921 gaaattatct atttgaaatt taaatctgat aatatattga gtgttccaat gagggctttg
     1981 atcctattat ccatatcttt ttcagtttta atattgatac acattataag aaaaagaaac
     2041 ttttggttaa tttatttcat cccagtgcaa aatataaaaa agtaaaatag accataggca
     2101 atagattaac aattaatata atacaagcaa atattctatt cattgtattt ctgctttcaa
     2161 aaagttctaa tattgaaagt ataattccac aaatgcctat aataagtatg ggaataagat
     2221 tagaaaataa caccccgagc caatctgtga aaattactat atttactaat atccctatta
     2281 acatacctat catatttatt aaatcaattt ttttcattag atatttctcc tttattaaat
     2341 ctgaagtact tatattaaaa taattctaaa ctatttacct caaaaagtgc aataaattat
     2401 ttctgaacaa taaaatgata gtcaaaacaa aaaaatattg ttaatcgttc agagccatcc
     2461 gagagtgtaa aatattttgt gtaaatgaaa aaatccatac aaaaaaggaa ggcgcttctg
     2521 tagaataaag ttaacgacaa ccaattcaca gaaaagagga cttccctatg aatgatttta
     2581 ctacagaaat tgtgcaaact ctagtcacta aaggcg
//
LOCUS       DAMEEU010000147         2498 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.153, whole genome shotgun sequence.
ACCESSION   DAMEEU010000147 DAMEEU010000000
VERSION     DAMEEU010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.153"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            98..391
                     /locus_tag="PB779_002833"
     CDS             98..391
                     /locus_tag="PB779_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740311.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
     gene            388..612
                     /locus_tag="PB779_002834"
     CDS             388..612
                     /locus_tag="PB779_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDE0740312.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            609..1634
                     /locus_tag="PB779_002835"
     CDS             609..1634
                     /locus_tag="PB779_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HDE0740313.1"
                     /translation="MKKKITITAMSLLTALFLLPINTFAYTINDEYNLAPNQGDSRLA
                     IPNKIILHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQGYVSWGAG
                     NANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTSLFTKGIIS
                     HLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGA
                     ANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADG
                     IYRPDVNQAYNTSGNVGYHVSFNMRNFPSKKVYVMMRATNDPEGNTKGGAQDFHDKRW
                     YLNIPKR"
     gene            1824..1897
                     /locus_tag="PB779_002836"
     tRNA            1824..1897
                     /locus_tag="PB779_002836"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1858..1860,aa:Ile,seq:cat)
BASE COUNT          836 a          413 c          487 g          762 t
ORIGIN      
        1 ttgtgcatta ctgaagaaga agcagataaa atcattagca aagaagagag cgcatcttaa
       61 ttgatgtgct ttttattttg attcaaggag ttgtcacatg attaatttag gggaatgggg
      121 agcgatagca ggatcaataa ccgctatcgt ttctttgatt ttattagtaa taaaaccaat
      181 tactgcatct ttctcgaaga ttactgagac tctttcaaaa gtaagtcaca atttagattt
      241 gctgactaaa gatttagaat cgagcaaatc agatcgattg atgattcatg aagaactaaa
      301 gaaacacgat gaaagattag atacacatac agaaaaattg gtggaacaca cgcaacaaat
      361 taaaacttta tttagggaga gaagaaaatg aataataaaa cgttcgaagt actaaaatgg
      421 ttcgcactgg taattattcc cgcactagct actttcgtgg ggttagttgg taaagcgctc
      481 aattggcagt acacagatat ctgtgttgtc atcattactg gttttggcgc gtttttaggg
      541 agtgtgttgg gtgtatcaaa tcgaacctac aaaatgttct cggctgaaag cgaagaagga
      601 ggaaacaaat gaaaaagaaa attactatta ctgcgatgag cctgttaacg gctctttttt
      661 tattacccat taatacgttt gcttatacta ttaatgacga gtataattta gcgccgaatc
      721 aaggagactc cagattagca attcctaaca aaattatttt gcacgaaact ggaatagatg
      781 caccagcaag aaacgtagcc gccaacatga aaaataatta taacggaagc aattcttata
      841 ctacagatgt tattggtgac ggtgggattg tttaccgtgt gggtgagcaa ggatatgttt
      901 cgtggggagc tggtaacgct aatccttatg cgcctgtaca gattgaatta cagcgcacat
      961 atgataaagc attgtttgaa aaaaactatc gagcttatat tgaatataca agagatagtg
     1021 caaaaaaata tggaattcca ttgactcttg atcaaggaac ttctttattt acaaaaggaa
     1081 tcatttctca tttgtgggtg acaaattatg tttgggggaa ccacacagat ccatatggtt
     1141 acttatcgca aatgggagtt agcaaagaaa agcttgctta tgatttagct catggattta
     1201 ccgatgaaaa tccaacaact tctgaaaaca agcctgtcat tgatccaaca cgagctggtg
     1261 cagctaatcc tacgctgaca gatggaacaa atcacgccca cattgatcag tttggggaaa
     1321 tcgaaaacgc aaacttgcat gtggctggat ggcacattgc taactataaa tacgagtata
     1381 ttttcattat ggactacaat actgggaaag aattagctcg agtaagagct gatggaattt
     1441 atagaccaga tgtaaaccaa gcttataata cttctggaaa tgttggttat catgtatctt
     1501 tcaatatgcg taattttcct agtaagaaag tctatgtaat gatgcgggca acgaatgatc
     1561 cagagggaaa cactaaaggc ggtgcgcaag atttccatga caaacgttgg tatttaaata
     1621 ttcctaaacg ataaaaatag ctcctcgttg aggagcagta cataactata ttgacaacta
     1681 taaaaattat tcgataaaat agtgatgtta tcgcatatct tcactatcac ccataaatag
     1741 tcacactcca agctatgcga taacaggttt gttgccacac attctactgg ttgattgttt
     1801 atggctttat gtggcaacaa ccagtaccct tagctcagtt ggtcagagca gacggctcat
     1861 aaccgtccgg tcgtaggttc gagtcctaca gggtacatta acgtagccat ttgaatcgtt
     1921 ctgtgttaga atttttttga agagtattat acaagctaaa gcttttcttc attgccactc
     1981 aaatgagtgg cttttttatg tatcctttta tggattaatg aaaggatgtt tcacatagtt
     2041 atacttctgt atatttgaaa agttttactt tgatttttaa atagaaagac atttgggtta
     2101 aattgtgaga taataataaa gaagagttta aagcgcaccc caaaccactt ccccataagt
     2161 gtgttacgct ttaaactctt ttatatttga agccattaaa aagcatacca tatttttgaa
     2221 aaaaagtgag aaaaaaggct tacaattgga gtggtagtta attagtgact tatttttgat
     2281 tttatagcac tgatactata aaatatagat atcatcatat tacacaatct taatactaac
     2341 ttaaaaaata tctcctttca caagtatggt gataaaattc gttccgggct acctttttag
     2401 gtagcctact ttaatcttta tacctttctg gatcaacgaa agtatacttt atatagtcat
     2461 aacgccgatg atcgctacgt gcgtccggca cgtcagtc
//
LOCUS       DAMEEU010000148         2439 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.154, whole genome shotgun sequence.
ACCESSION   DAMEEU010000148 DAMEEU010000000
VERSION     DAMEEU010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2439
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.154"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            403..1020
                     /locus_tag="PB779_002837"
     CDS             403..1020
                     /locus_tag="PB779_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDE0740314.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            1061..1360
                     /locus_tag="PB779_002838"
     CDS             1061..1360
                     /locus_tag="PB779_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HDE0740315.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            1394..1561
                     /locus_tag="PB779_002839"
     CDS             1394..1561
                     /locus_tag="PB779_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HDE0740316.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(1606..2211)
                     /locus_tag="PB779_002840"
     CDS             complement(1606..2211)
                     /locus_tag="PB779_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDE0740317.1"
                     /translation="MGKIGYIRVSSQDQNLDRQLAMMEGLNIDKLFQEKASGKDTERP
                     EFQKLLNYIREGDCVIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGN
                     ELLDTAMFDMFLSLLSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQ
                     KRLVFKTVVDMLKQGIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT          832 a          376 c          451 g          780 t
ORIGIN      
        1 tatattgtaa aggcaaaagt atcaaaaaga tttattttta accctaaatt agaaatatat
       61 agtgttgtaa tagaataata gtgttaaaaa aattgtaaaa gttaaagaag tcaaattctg
      121 atgtgaaaaa taaaatatac catggaagac ataaaagaaa aactggataa ctagtttatt
      181 taatggcaga ccgttaaggc ctgccatttt tatgtatttt agcggaataa atataatcat
      241 gcgggagtgt aaacttactg tttcaaaaag tatacttttt gacatgcctt gattttcttt
      301 gtttatgtat ggcataataa ccacataata caatttgaaa cgtttctgat ttaatctgat
      361 tgttttgaaa caattttagt gaaaaaaggg tagataaaaa cgatgagaaa atttttttat
      421 atccgggtca gtagttatga tcaatcgatc gaacgacaac tgatttccgc gaaggaatta
      481 ggaatccctg aagaatatat atttgtagaa aaagccagcg gcaaagattt taaacgccct
      541 gaatatcaat taatgaaacg gatgtttcga aaaggagatt tactctatct acaatcatta
      601 gatagactag gcagaaataa acaaatgatt ttagaagaat ggcgagaatt aactaaggaa
      661 aagcagattg atatttctgt gttagacatg cctctgttag atactgctag ttacaagcaa
      721 ctagatgggt tagagacgct tatctctgac ttaattctgc aattactcag ctatatggcc
      781 gaagacgagc ggaaacgaat taatagccgg caaagagaag gcgtagaagc tgcgaaacaa
      841 aagggtgtaa aattcggcag aaagaaaatt gctttacctc ctgaatttcc tgcgatctat
      901 tctgactgga aagcaggaaa gataactgca gtctatgcta tggatcaatt gggcatgaaa
      961 cgaaatacct tttatcgacg ggtgaaagaa tatgaacata ccttgcacca cttttcttga
     1021 tagatataac agctattaga cgggaaggga gagtttgaaa atggacttaa cgaatcaaag
     1081 ggtcgttttt actggaacgc tgcagcaaat gacacgaacc caagccatcg gtttggttca
     1141 ctctttaaac ggccattgtc aatcaagtgt tacttcaaaa acaaatttcc tggtttgtgg
     1201 tcagtattct aagtcgttgt ttgatgattc tctctataca aaaaaggaac aaaccgcgcg
     1261 ggacttgatt gcgttaggtc atgagattac cattttatca gaagtcgaat tttatgcgtt
     1321 aattagtcaa cagttgaaag aatggcaacg gtatttataa tcgttagtaa aatttacaag
     1381 gaggaaaatt tttatgaagc gaaaatctta tgatcgttgg ggcattgaaa taactagttt
     1441 taatcgaaat attgcttttc acgtggagtg tgactgtggg gaattagcaa aaagtgttta
     1501 tcaaaaaaat tacttttact gtcctaaatg ccatcgccga tacggggtac atggaacata
     1561 gaaacgaaat agtgcggtag aaaagcgaat gaatgtagta tatttctaca aatcattcgc
     1621 tttctttatt ttataaatag ttggtcgaga gatcccgttt tcttttgcaa tctctgcaac
     1681 tggaatgcct tgctttaaca tgtccaccac ggttttaaaa actaagcgtt tttgcggatc
     1741 tgttgagtta atagaatact cgattggtcg tcccttatat cggccggctt tttgagccaa
     1801 taatactcct tgccgctgac gttcacgaat tttctcacgc tcgttttgtg caatataact
     1861 tagcagtgat aaaaacatat cgaacatagc ggtatccagg agttcatttc cagtattaaa
     1921 atctaaaaac tgtgcatcta atatttttaa cgctactttt ttctgtttca taaaagcaac
     1981 tgtatttttt atatcttcat aatctcttcc taaacgatct agtgatgtaa cgatgacgca
     2041 atcaccttca cggatataat ttagtaattt ttgaaactca ggacgctcag tatctttacc
     2101 actggctttt tcttggaata atttatcaat gttaagtcct tccatcattg ccaattgtcg
     2161 atccaaattt tgatcttgtg aagatactcg aatatagcca atttttccca taaaaaactc
     2221 ctttttaaaa gtgatataat ttacatgtaa aatttacttg tagttttact gctatcatag
     2281 catttttaaa aataaatttt atgtagactt aaaatttact tcatggaggg tttaaatgga
     2341 tgaaatcaaa agtaacaaaa aagcatttgg catttattta ggagaaccta gtacagaaca
     2401 attaaaccaa ttttttggtt ctgttgcgaa gtttgaaaa
//
LOCUS       DAMEEU010000149         2399 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.155, whole genome shotgun sequence.
ACCESSION   DAMEEU010000149 DAMEEU010000000
VERSION     DAMEEU010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2399
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.155"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            207..2070
                     /locus_tag="PB779_002841"
                     /pseudo
     CDS             207..2070
                     /locus_tag="PB779_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
     gene            2070..>2399
                     /locus_tag="PB779_002842"
     CDS             2070..>2399
                     /locus_tag="PB779_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HDE0740318.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          866 a          353 c          466 g          714 t
ORIGIN      
        1 aaaaatttga aaaagcgttt gattatttat attacgactt agtgcaataa aaaacgcttt
       61 ttaacagtac atgtagtcgt ctttataata gataaactct gtaatattag ttaaaaagct
      121 ataagttgca cttagttaag tgcaaacatt tcatattgtc gttagtttag aaaacgctta
      181 tattagcaat gtaaggagag atgataatgc agcagctaac aaaaagagaa aggcagcttt
      241 tgatttactt ggtggaaatg tctgaaccgg taacaatcaa aaagttggct gaaaaagaaa
      301 atgttagtgt tcggacgata aaatacgatc tagatgatat aagagagtgg ctgaatgagc
      361 ggaagcaagt cctatatagc aaacgtagtc agggaatttg gatgaatatt agtagctctg
      421 atcgaatcaa attaaaaagc gaattgatgg atgttaatcg ttttgaaata tttgcagatc
      481 aaagtctccg aatcaaacgt ttactaatta tgcttttagt aacaaaagaa gctattactg
      541 gaatgaaaat ggccaacgca ttagatgtca gcaaagatac gatcatgaat gatttagatg
      601 tgctggaaaa taattttctt aaggaaggat tgaccttgaa tcgtcaggcg cgaaagggtt
      661 tttggatcat aggagaagaa cgtctagttc gattaacgat tgaagagatt cttcaaaaag
      721 agttcacgga ttatgacatt tataaattaa tgtcattgtt attgaatggc ggtgagactg
      781 aatactttga aatgtattct gctactgcta cacctatcca agaggtattt aatcaagtaa
      841 tcattcgaat gcgacactta ctggaatttg aaaatctaga gaaactgaat tacgcggaat
      901 tactaaatat tctgattcga gtgacaattg ctaccgttcg cttacgcaaa gaggctacga
      961 ttggtcgtta tcaattggtt gctgaacaag aattagacaa aaacgatctt tcttatcgcg
     1021 tcatgcagca ggtctttgat tattatcagt tgccactgtt cgaggatgaa tatcattata
     1081 tctatagtga tacattcgac acgattcacc agcaagacgt catgaaacta gttgagaatg
     1141 tgatttataa agtaagtaaa gcaatcaacc attcttttta tcaagatcca caattgttga
     1201 cgaatctgta tgctcattta tccatgcgat tatcgagaaa gaaaaaattt gtcaatgaat
     1261 ataatccttt taaagaagat atcaagcaga aatacccgga attatttgat gcgatcaagc
     1321 aagcagttcg acaagaaata agtgaacaaa atattctgat caatgattct ttcgtggcat
     1381 atattgcctt acactttttg gtttcctacg aaagagaaga agatctacga agcgttagag
     1441 ccgtctacat ttgttcaaca gggttgggtg tgactagtct gatcaagcaa aagatcaatg
     1501 aagaattaaa taatatcact atcgtggcat ttgcttcagt attgaatgcg caagaaatga
     1561 ttgctaccaa agatcctgat ttggtgaatt agtatttttc caattaatgg catcgatcgt
     1621 cctttcatca aagtccatcc attacccact gaacaggact tgaaaaaaat tcaacaaata
     1681 ataaaaaaaa tacttgcttc ttccaatcag caggaaaggc ataacttgaa tcttagagaa
     1741 acgtccatca ataaagatac tttagaagac tttagcaagg aattgatttt gaaagcttat
     1801 acgatttatg aacgtttact tgtcattttg gaagcagaat tgatccaaga atatcgagaa
     1861 gcttttttgc ttcatgtatt cttaatggtt catcgtatca catttgatca acaatatatg
     1921 gcagaaggtc gtcaagtaga ccagattatt ttagacaaag gaacactggt aggaaaaatc
     1981 gaagcagttt ttgcagaaaa taatttagga atcaatcagt cagaaatcag tgcattattc
     2041 tcatatataa aagaaggagc gtcaagttag tgaaaatgtc agacgaggct ttaaaaatta
     2101 tcgaggaaag tcaaaatcgg gaaaagttaa aacaagtgat tgatctaatt gaagagcgat
     2161 tagtagaaca tgctattgta ccaaccgagt tgcagtggac cattctaatt aatcacttga
     2221 atgagatgct gaaacgttct caaagaaagg aaacgattcc cgtagtcgat cgggatttgt
     2281 tcaaagaagt atccaaagaa gccataacta tttctgatga aatagttaga agtatcggta
     2341 atttaaccga tgatgaaata tatgttttgt cgattcattt tgaaacagca aaaaataat
//
LOCUS       DAMEEU010000150         2362 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.156, whole genome shotgun sequence.
ACCESSION   DAMEEU010000150 DAMEEU010000000
VERSION     DAMEEU010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.156"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..314
                     /locus_tag="PB779_002843"
     CDS             <1..314
                     /locus_tag="PB779_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HDE0740319.1"
                     /translation="FGEPKAIVTDKAPSLGSAFRKLQSVGLYTKTEHRTVKYMNNLIE
                     QDHRPIKRRNKFYRSLRTASSTIKGMETIRGIYKKNRRNGTLFGFSVSTEIKVLMGIP
                     A"
     gene            397..1014
                     /locus_tag="PB779_002844"
     CDS             397..1014
                     /locus_tag="PB779_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011834674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740320.1"
                     /translation="MWIFKQEIFAKLFSLDGLGWGILFFIFLFLGSMWIWFVDKKNSY
                     EKVIVKKMNRNEFDDFSKEHRVELYDSHEINSTSPSYYWVFGCEEKPLEIKLLKMLEN
                     PPVIEDFSAKNVEKQMFEQVQIRGQNKISLEPDEYAAFFLETNSGTSMPVFKVKLKMN
                     GRLCTYDLVANMRYGSTGDRRTILKFEQTFRSFLKNRVSQIFNLD"
     gene            1178..1510
                     /locus_tag="PB779_002845"
     CDS             1178..1510
                     /locus_tag="PB779_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740321.1"
                     /translation="MNNREILAKEMADLKAKEAKIRAKRKQIRQKEMISLAKLYCKKE
                     GFKTPAEALDFLESNKRNHSVNDEVLVSLRKFADGLVWQENGAYWRTNDVKGLTQFMA
                     QFRSENVN"
     gene            1834..1995
                     /locus_tag="PB779_002846"
     CDS             1834..1995
                     /locus_tag="PB779_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
                     /protein_id="HDE0740322.1"
                     /translation="MAYMVARTQKHKVGSLNGLQNHVDRKTKNHTNKDIDITKSGSVA
                     KFSKKSILV"
     gene            2027..2362
                     /locus_tag="PB779_002847"
                     /pseudo
     CDS             2027..2362
                     /locus_tag="PB779_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
BASE COUNT          834 a          316 c          483 g          729 t
ORIGIN      
        1 agtttggtga gccgaaagca attgtgaccg ataaagcacc ttctcttggc tccgccttta
       61 gaaagttaca gagtgtgggt ttatatacta agacagagca ccgaactgtg aagtatatga
      121 acaatttaat agaacaagac catcgaccta ttaagcgacg gaataaattt tatcgaagtc
      181 tccggactgc ctcatccacg attaagggga tggagaccat tcgaggaata tataaaaaga
      241 accgaagaaa tggaacgctc ttcggctttt cggtgtctac tgagatcaag gtattaatgg
      301 gaataccagc ctaagatatt tggagttcag agagggcgcg tttgattttc aaacttcgca
      361 acagaaccat tattttaaag tgggaggaaa attgttttgt ggatatttaa acaagaaatc
      421 tttgctaaat tatttagttt agatggatta ggttggggaa tcttattttt tattttttta
      481 tttttaggat ctatgtggat ctggtttgtt gataaaaaaa attcttatga gaaagtaata
      541 gtgaaaaaaa tgaatcgaaa tgaattcgat gatttttcaa aggaacatag agttgaattg
      601 tacgatagtc atgaaattaa cagtacttct ccatcttatt attgggtatt tggttgcgaa
      661 gaaaaaccat tggagattaa attgttgaaa atgcttgaaa atcctccagt cattgaagat
      721 ttttctgcaa aaaacgttga aaaacagatg tttgaacagg tacaaataag aggtcaaaac
      781 aaaatttcat tagaaccaga tgaatatgca gccttttttt tagaaacaaa ttcaggtact
      841 tcaatgcctg ttttcaaagt taaattaaaa atgaatggtc gtttatgcac ttatgatctt
      901 gttgcaaata tgcgctatgg ttctactggt gatagacgta ctattttaaa atttgagcaa
      961 acctttagaa gttttttgaa aaatagagta tcccaaattt ttaatttgga ttgaaaaaat
     1021 taaaaatttg gccaaaaata ctacagtttt ttagagcaat catcttatga tgattgctct
     1081 ttttttgttg tttttgtgtc attcgttgtt caaatcctct attcgtaaaa taaatatttt
     1141 aaactagaaa tatgccttat ttttaggagg aatcaaaatg aacaatagag aaatattggc
     1201 aaaagaaatg gcggatttga aagcaaaaga agcgaagatt agagcgaaac gaaaacagat
     1261 tagacagaaa gaaatgattt ctttagcgaa attatattgt aaaaaggaag gctttaagac
     1321 acctgctgaa gcattagatt ttttggaatc aaataaaaga aatcattcag taaatgatga
     1381 ggttttagta tcgctaagaa aatttgcaga tggattagtt tggcaagaaa atggtgcata
     1441 ttggcgtacg aatgatgtta agggtttgac tcaatttatg gcacaatttc gttcagaaaa
     1501 tgtgaactaa attgaggagg ggttgaagtg aaaagcaata cttttcactt ttggtttttt
     1561 gcggaataaa aattgtgaaa acaatgacgc aaaaagccaa tggttttgaa cgaaaaaagg
     1621 acgtaaaaaa ggaatgcgaa ggcagtcgtt tttcgttcgc tttttcgttt gagagaaacg
     1681 gagtttctca tcggctgtta agccgatata gccctcggca gagcttacag actttacgca
     1741 gtataagtct agtaagttat accttacatg gaggtttttc cgaatttagc ttgtgattct
     1801 cgcaataatt ttaacgaaag gaagtacaca gttatggcct atatggtggc acgaacacaa
     1861 aagcataaag ttgggtcgtt aaatggactt caaaatcatg tagatcgtaa aacgaaaaat
     1921 catacgaata aagacattga tattacgaaa agtggttctg ttgcaaagtt ttccaaaaaa
     1981 tctattttag tgtaaaattg agaaaaaaga cagagaggat agagtaatga atcattttaa
     2041 aggcaaacaa ttcaaaaaat gacgtcatta ttgtcgctgt tagttactac ctgcgttaca
     2101 atctaagcta tcgtgaagtt caggaattgt tatatgatcg tggaataaat gtttgtcata
     2161 ctacgattta tcgttgggtg caagagtaca gcaaagtcct cgattatctt tggaagaaga
     2221 aaaatagaca atccttctat tcatggaaaa tggacgaaac ctatatcaaa attaagggac
     2281 attggcatta tctttatcgt gcaattgatg cggacggctt aaccttagat atctggttac
     2341 gaaagaaacg ggatacgcaa gc
//
LOCUS       DAMEEU010000151         2266 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.157, whole genome shotgun sequence.
ACCESSION   DAMEEU010000151 DAMEEU010000000
VERSION     DAMEEU010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.157"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            103..>2266
                     /locus_tag="PB779_002848"
     CDS             103..>2266
                     /locus_tag="PB779_002848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cna B-type domain-containing protein"
                     /protein_id="HDE0740323.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
BASE COUNT          891 a          348 c          448 g          579 t
ORIGIN      
        1 agttaaaaga ttggaaatga gtgggggagg aattgaagaa aggatttttg agagatgata
       61 tagtaggttt tatttttagt taaaataggg gagatagaaa aaatgaaaaa gtgtagaaat
      121 attattttat caatgttatt tattattact aatataacat cactgattcc tgttcatgtc
      181 tatgcggatg caggcagaga tatcagcagt aatgtcactt cgttgaccgt ggacccaacg
      241 aatattacag atggaggaaa cataaaagta aaattctcgt ttgacgaaaa aaaacaaaat
      301 atccaaccag gtgattatct ttggatcaat tggccaagtg aaggaaatat tcgcggtgaa
      361 ggattccaaa aagaaatccc attaatgatt gaaaataaaa atgttggaac tttaacggtc
      421 agaaaagatt ctgcgcaggt tgtgtttaat gaaaatatta aaaacctaga ctcagtagaa
      481 ggttgggggc aatttgagat acaggccaga aacgtaaccg ataccggtga agaaaatacg
      541 ggaccattca ccgtgacgag cggtgataaa acagctactg taaatgtgac aaagccagct
      601 tctggttctt cttctagcgt tttttattat aaaacaggag acatgctacc tgaagatact
      661 aagcacattc gatggttttt gaatattaac aataacggca cttatgttga acaaccagtt
      721 aaaatcagtg atgaaatcca aagtggacaa agattagatc caagtacgtt tgaaattaat
      781 caaatacact taggtgaaca gaaggtttat agaggagaag agggaatcca acaattttta
      841 caagatttcc ccagcgctac atttaatttt tcagtaactg ataattacat tgaaataact
      901 ataccaaaaa actttgtcaa tcttaggaaa ataatggtga gttataagac gatcatagaa
      961 aacccagaac aaataaattt tgagaatcat tcggaagctt ggtttaaaga atttaataaa
     1021 cctgctgttg atggagaaag tttcaatcat acagttaaaa atatttcagc ttctggtgga
     1081 gtcaacggta cagttagagg cgaattgaag attttcaaat atatcaatga cacagagatt
     1141 ggtatcccaa atgtgacttt cgaattaaga cgagcagatg aacagcctat tcaaggacag
     1201 tctagtatcc tgttgacttc gaatgaacag ggagaagcta gtatcaaagg cctgcaagta
     1261 ggagactatg ttgtaaaaga aaaagaagca cccaattgga ttgattttga tccactaagt
     1321 tcaaatgaac tcaaattctc cataaacgaa aatgatacag agggagtcag tttacctatt
     1381 tataacaaga aaaaggttac gaacatcaca gcaactaaaa tttggaacgg tggaaccact
     1441 ccaagaccga gtatttattt taaattattc agagcaagta caaacaattg ggaaccagtt
     1501 cctgatgcag aaacaaaacg attagacaat ggaataactt cagtgacttg ggaagatatc
     1561 caacagtatg atgatagtgg aaacgaatat acgtttaaag tgcaagaagt agatcaaaac
     1621 ggaaatgatt atgtcccttc aggttatcaa aaaattgaaa acgggctagt cgttacaaat
     1681 gagaataaag aagtcatttc agtctcagga caaaaaacat gggaagacaa tgagaaccaa
     1741 gacggcaaac gaccgacgac gatcacagta aatctattag ccgacggtca accgatccaa
     1801 cacaaagaag taagtgaaaa agatgattgg cgctatcgtt tcacaaatct gccaaaatac
     1861 agagacgggc aagaaatcat ctatactgta acggaagaca acgtgcccga atacagtacg
     1921 acgattgacg ggtataacat caaaaacagt tatacaccgg aaaaaacaaa tatatctata
     1981 ccaggtagcc atataacacc gtggaaaaat tttccagaga agacagagag agagaaaatt
     2041 agaaatctat tctctcaaaa attgcaaata tttgctcata caggagaatc cagcgaacaa
     2101 agaagcaatt atattagtaa gagagctgta cctaaacaga taacaaataa atcaaaaagc
     2161 attcttccta aaacaagtag taaaaaatct agttttgctg taatcattgg tttattgata
     2221 gtaactatct gtgctgggat attcttacaa aaatataaaa aagttt
//
LOCUS       DAMEEU010000152         2240 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.158, whole genome shotgun sequence.
ACCESSION   DAMEEU010000152 DAMEEU010000000
VERSION     DAMEEU010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2240
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.158"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            1581..>2240
                     /locus_tag="PB779_002849"
     CDS             1581..>2240
                     /locus_tag="PB779_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS6770 family transposase"
                     /protein_id="HDE0740324.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCGRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERPVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPHFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SI"
BASE COUNT          829 a          306 c          438 g          667 t
ORIGIN      
        1 attatcgaac acctttggaa gtatttttga gttacgtaag tattgatgat ctgtctaatt
       61 taatttgaca attaagaaag tattaacttg ttttgtgaaa aagagaattt gaaaaacgat
      121 tggcgaacaa atgctcggta ggtatggtat aaatacagag ctaattggtg tgatgaaatc
      181 agatattcgc gtgagattca gtaaagtagg agttcgaaaa cagctaggtg acaaacagta
      241 ttgctttggt acttcggaat ggtttatcaa attcttatca acagttcact tctctttatg
      301 tttgagtgat gattcgttag gttattgctt ggaaagaccg gatgagagta gaagagttta
      361 attttataaa gtgaaaagag gtaatgtacg atatacgtag ggctgaacca atagaggata
      421 agcaaacgat gttacaggcg caaaattcat agcttactgt tttggagata acagaagagg
      481 aaataatgca gaagtaaggc gaaaaaagga cggaagccta acagcatatg aaataaagaa
      541 aaatattata actactgata aatcggtatt gagcaaagta ctaataggag tcaaaaacat
      601 tcataagcta tgagtgtttc ttggctactt ttttattttt atgtatctac aaaagtttcc
      661 aggggcagaa cctgtgatta ttaatggaag aacctcaagt attgtcttaa atcattgtta
      721 tgaaaatgga ttaaaagagt tcatcaaggt gtgattaaca agttactttt cattacatcg
      781 aatttttcag aagttgctta tattggtgat gatattaatg atttatcatg tatgacatct
      841 gtgaagaagc gggaggaata gtagaatgtc caaaaaatgc cacaagaaat gagattgaat
      901 tatctgattt tattgtaact cacagtggtg gtgacgaatc tgtgatagag tttattgagt
      961 ggatattgga atcgatatag tgtagtagta cagaaaaatt atcatacaat taatactagg
     1021 cataagaata ttggcatatt ctagagttaa aagtaactat tcgaaaagga taaggttaga
     1081 attttttgtt ttgccagtgg aagaatataa aaagggcatt ggaaattaat atattagaat
     1141 gctaagcgga gaaaaaaata tatgaaaagt acgtccttgt gatgggatgg aaaaatacac
     1201 ttatttcaaa caacgataat ataattatgt gaaccgaagt atactcgctt ctaattcaat
     1261 cctcaaatcc cgacagtcgc gacttcaaaa aagcgtatag ttttaatgta tccccatatg
     1321 atccgaaaaa tggtaattta caattaacag tttgatgatg ttgaagatgt ggaaatgctg
     1381 aaattaccat gatgagaaac acattaatta aagggaatta attaactaga atataatctg
     1441 attcaatttg aattaagcaa aaaaaggctg agttttaaat aatcgcgaat tgtaaaatta
     1501 agttagaaaa ataaaaaggc atttatggta cactcaaatt gtatttccga cgaaagaaaa
     1561 caaaggagtg taacccataa atgacctaca aacatcttac catagacgaa ctgacaatga
     1621 tagaatcata ttatcttcaa cataataagc cggttgaaat cgctaaccga atgggacgtg
     1681 ctatacaaac tatttataat gtagtcaata agttcaagca aggcaagact gctcttgatt
     1741 attggcacca gtataaagaa aataagaaaa aatgtggtag aaaagtcatt caattacctg
     1801 ctcatgaagt agattacatt aaagagaaag tcactcttgg ttggacgcct gacgtcatta
     1861 tcgggcgaaa agaaaggcct gtttcatgcg gtatgagaac actttatcgt ttattttcta
     1921 aaggaatatt tgatattgac acactaccga tgaaaggtaa aagaaaaccc aatggccatc
     1981 aggaaaaacg gggaaaacaa cagtatcagc gctcaatcca tgatcgacct gataattatc
     2041 ctcatttcaa ttctgagttt ggtcaccttg aaggtgatac gatcgttggc attcatcata
     2101 aaagtgccgt cattacttta gttgaaagat tatctaaagt cattatcacg attaaaccca
     2161 acggccgtaa ggcattagat attgaaactg cccttaatca atggttttct cgcttcccta
     2221 aaaacttctt taaatctatt
//
LOCUS       DAMEEU010000153         2236 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.159, whole genome shotgun sequence.
ACCESSION   DAMEEU010000153 DAMEEU010000000
VERSION     DAMEEU010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2236)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2236)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2236
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.159"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            342..1301
                     /locus_tag="PB779_002850"
     CDS             342..1301
                     /locus_tag="PB779_002850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDE0740325.1"
                     /translation="MTYTHLTPTELVMIEAYFNQSHSVSKVAHLVQRSRQTIYNVYRF
                     LKSGGSAISYYEQYKKNKRNCGRRPIVLPDGQQEYIQKKVAQGWTPDVLIGRAEFPIA
                     CSVRTLYRMFKDKTFDPHDLPMKGKRKPNGHKEKRGKQAFRRSIQDRTTDYIQFNHEF
                     GHLEGDTIVGGKHKSAVITLVERLSKVIITLKPAGRQAIDIENRLNQWFQSVPKHLFK
                     SITFDCGKEFSNWKKISNTNDISIYFADPGTPSQRGLNEHSNGLLRKDGLYKAMDFNK
                     VSETFIQSVASKRNHIPRKSLHYRTPLEVFLSYVGKDDLSSLI"
     gene            complement(1288..1893)
                     /locus_tag="PB779_002851"
     CDS             complement(1288..1893)
                     /locus_tag="PB779_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740326.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     LIYKIIEDDKQTELNMCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNS
                     LDFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKVSFVKLS"
     gene            complement(2133..>2236)
                     /locus_tag="PB779_002852"
     CDS             complement(2133..>2236)
                     /locus_tag="PB779_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740327.1"
                     /translation="WTCPICHTHHDRDINASINILTEGLRLHSMGLA"
BASE COUNT          739 a          387 c          354 g          756 t
ORIGIN      
        1 tttaaaatta ggagcagtgc caattgtttt aattttaaag gcttttttta tatcttctaa
       61 attagaagat atttgtatat caatatggaa tatattacct tttttgtatt tttttatgtt
      121 atctttagct aaaacatcaa atacatgtcc ttgaaattgt atcgaggcag ctggatttag
      181 tttaaattga ggaaacttta ccacagctga ttcaaaacac ttgtcacatt tttttatttt
      241 tttaccttcg ccgattgtaa aattaagcta gacaactaaa aaagtcattt gtgctacact
      301 caaaatagtt ccgtcgaaag aattataagg agtgagtaca aatgacctat acccatctta
      361 caccaactga actcgtaatg atagaagctt atttcaatca atcacactct gtttcaaaag
      421 tagcccatct ggtacaacgt tctcgacaaa ccatttataa tgtctatcgt tttcttaaat
      481 ctggtggaag cgcaataagc tactatgaac aatataagaa aaacaaacgt aactgcggaa
      541 gacgtccgat tgtgttacca gatgggcaac aagaatacat tcaaaaaaag gtggctcaag
      601 ggtggactcc agatgtcctt attggtcgag cagagtttcc tattgcttgt tcggtacgta
      661 cactatatcg gatgtttaaa gataaaacct ttgaccctca cgatttacca atgaaaggga
      721 aaagaaaacc aaacggacat aaagaaaaaa gaggaaaaca agcttttcgc cgttcgattc
      781 aggatagaac aactgattat atacagttca atcatgagtt tggtcaccta gaaggtgaca
      841 ccattgtcgg tggaaaacat aaaagtgcgg tgatcacgtt agttgagcga ttatctaaag
      901 tgatcatcac cttgaaaccc gctggtaggc aagctataga tattgagaat agactgaatc
      961 aatggtttca atctgtaccg aaacacttgt ttaaatccat cacatttgat tgtggaaaag
     1021 agttctcgaa ttggaaaaag attagtaata ccaatgatat ttcgatttat ttcgctgatc
     1081 caggaacacc ttctcaacga ggactaaatg aacattcgaa tggcttatta cgtaaagatg
     1141 gcttatataa agctatggat tttaataagg tatccgaaac ctttatccaa tcggtggcat
     1201 caaaacgaaa tcatattcct agaaaatcat tacactatcg cacaccattg gaagtatttt
     1261 tgagttacgt aggtaaagat gatttgtcta gcttaatttg acaaacgaaa ctttgtaaaa
     1321 atattcgatt gaatattcta tttggcacga ctcacttggc agtatatgta tgtcaatatt
     1381 tttcatctgt ttcataggta tttcaaaatc taaactatta aaaacatata attccctgta
     1441 attatttaca tctaactcta ctaaatttat ctttggaaca atagatcctc cacccattcc
     1501 accataataa aaaaaatctt gttctctatc aaaatagcac atattaagct cagtttgttt
     1561 atcatcctca ataattttat aaatcaaacc tatataatca tgaatgctgg caaaaatttt
     1621 ttttaagtca agttctaaat cttcttcgaa aacacattta atttctccta ctgataattg
     1681 atactctata ttacatgact taattagttt tttagatccc ccctccagat aggcatatgt
     1741 ttcaataatt atgttctttt tattgcttgg caaatttccg ttatttattg cataaattaa
     1801 aaatgactgt ctatttagcc cataatctaa tacaacttct tcatactcat atttctttaa
     1861 atatttaata tgaaaatatg ctgaattaat caaaactcga gtgttactgt tgttatttat
     1921 tgttgttcta ttgtgtataa aattgtatag gttgtcatat tttcttggtt tagtgaacta
     1981 ctcaccactt agctaaacct aacggtttct tacgtttgaa gtgggagctt cttgggaaga
     2041 gagcatactt gatagcgtat tactttacta acagaggtgc ctcttattta ccaagctatc
     2101 cccgtagttc ctacggttct tgtttatttg atctaagcca atcccataga gtgtagcctt
     2161 agaccttcgg tcaggatatt gatactagcg ttgatatctc ggtcatgatg agtatgacaa
     2221 atagggcaag tccatt
//
LOCUS       DAMEEU010000154         2155 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.160, whole genome shotgun sequence.
ACCESSION   DAMEEU010000154 DAMEEU010000000
VERSION     DAMEEU010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2155)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2155)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2155
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.160"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..245)
                     /locus_tag="PB779_002853"
     CDS             complement(<1..245)
                     /locus_tag="PB779_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740328.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQF"
     gene            complement(247..1674)
                     /locus_tag="PB779_002854"
     CDS             complement(247..1674)
                     /locus_tag="PB779_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HDE0740329.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKEN"
     gene            complement(1667..>2155)
                     /locus_tag="PB779_002855"
     CDS             complement(1667..>2155)
                     /locus_tag="PB779_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HDE0740330.1"
                     /translation="FRAIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQ
                     MYEQNQQDYLNFKIGMFAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQT
                     SKLANIHIIDPSMNKWFDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNI
                     DE"
BASE COUNT          816 a          350 c          255 g          734 t
ORIGIN      
        1 aaaaattgat tatggttagt taacaagtta attttacgtt taaaggaaga accgattttc
       61 cggtgattca caaaaacaac atcattaaat agccctaatt cttttatacg ctcactatat
      121 cttctagcgt tttcaaattc agaataaata aataaatctc cttttgattc tcggtaaaaa
      181 ttttgataaa catttaatat attaatcaaa tgtaaaggag tccaagcaat gaaagctgtc
      241 ttcatattaa ttctcctttt ttaaatacaa gtaagaaatg cttcccaaat aataccagaa
      301 aacaattgaa atgacatcgc gcttattgaa aagtacatga gcctccacca tttcatctat
      361 aaaaatagat agtataaaaa ttaaaacaat accaagaaac gcataattca ctttacttct
      421 aaaaaatgtt ttgagtaaac taaagatatt taacacatag aaagcataga tacatataaa
      481 agcaattata ccacttgata caagtacttg aagaaatcca ttatgcatgt ttccatgtgc
      541 tctttttagt tcattcacat ctgtagtatc aagatctact tttttcaaaa attttgcatc
      601 gctattccca tagaaatcgg tctctccata accaaataac aaagttggtc ttataacttt
      661 aagcgcagct ttccaaatcg taaaacgacc agctgaaatt tcggagttat cactagaatg
      721 ctgtaatatt acttcttttt ctggaagtgg agttttatct gattcatttg actctataac
      781 ttctactttt ctatcaatcg atacaggaat tgttgctaaa aaatccttag cataattagt
      841 accaaaagaa aaatatacca atagaactaa taatatgctt accatccatt tgatttttac
      901 aggtagtact tctctaatgc tctttctaaa ttttgaattg gcaaacaaca aaagaaataa
      961 tactaaaaaa gaacaaatta ctacctgggc acctctagac gaagaaagtg taatataaaa
     1021 tatttgtacg ataaaattca tcatataaaa aacacgaatc gtttttgtta tttttgaaat
     1081 taatacacta attaaactta aaataataga agtatatcca aacatagctc caacatttgg
     1141 acttgtatag acaccaaata accgatgttc aataaaacct tgtcttgcaa gtaatcctgg
     1201 cgttcctgtt gggacatgat aagaaatcaa aaaaataaat tgatagatag atattagcgc
     1261 agctaaaaaa attatgataa tgaaaacatt attaaaatac accatttttt tctttttttc
     1321 ctcttcactt tgtgaaaagt ctgcaggaaa aattactatc aaagtaatca gcaaatatcc
     1381 aaaattataa atagatggaa ttaaaaaatt ttctctgtta atgattatag ttaagataaa
     1441 actaatcatt gctccaatca gtagccaaga aaaacgcatt ttaaaaaaat ttttctttat
     1501 aaaaacctca tacaaaacta taattccacc ccaagcaaaa gctattttca tcgggatatt
     1561 agttacatta aaagtactag gcataaaata aagcagacaa atgattaaat ttattactcg
     1621 aaacgcatct cgacttaata aactcttctc taaaacaggt actattctat tcatctatat
     1681 ttccaacttt caaaatttct ttatcaattc tatttaatag tttatcagag taatccgatt
     1741 taacttttct tacaaataat ttttcacttt cttttatttg atctatatcc ctttcatcaa
     1801 accatttgtt catggaagga tcaataatat gaatatttgc taatttcgaa gtttgtaaag
     1861 tagtttcttc aatatttttc aattcaagtg gtaaatctgg tcctccaata acatttttat
     1921 ttttgaacga ggaattaaaa aaaagtgtat gaaaaaattt ttcatctggg gcaaacatac
     1981 ctattttaaa attcaggtag tcttgttgat tttgttcata catttgtatt aattctgtta
     2041 ggcattcttt cgacaaagcc caccattgag aaccatgata caaatcaaat ttatggtgtc
     2101 taatttttgg gggaagttta atcatcctca gacaacgatt aattatagct ctaaa
//
LOCUS       DAMEEU010000155         2088 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.161, whole genome shotgun sequence.
ACCESSION   DAMEEU010000155 DAMEEU010000000
VERSION     DAMEEU010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.161"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            1..492
                     /locus_tag="PB779_002856"
     CDS             1..492
                     /locus_tag="PB779_002856"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HDE0740331.1"
                     /translation="MSSITLIIFLILILLVVLVPRIFGLTPYIIEDKEMSPYYAQGNL
                     IYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTKTYIEPGVVK
                     KRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVELKKKRRRTQ
                     KFL"
     gene            620..1303
                     /locus_tag="PB779_002857"
     CDS             620..1303
                     /locus_tag="PB779_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HDE0740332.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1612..1685
                     /locus_tag="PB779_002858"
     tRNA            1612..1685
                     /locus_tag="PB779_002858"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1646..1648,aa:Arg,seq:tct)
     gene            1844..>2088
                     /locus_tag="PB779_002859"
     CDS             1844..>2088
                     /locus_tag="PB779_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HDE0740333.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITS"
BASE COUNT          700 a          328 c          427 g          633 t
ORIGIN      
        1 ataagttcta taacgttgat tatattttta attcttattc ttctcgtcgt cttggttccc
       61 cgaatttttg gtttgactcc ttatattatt gaggacaaag aaatgagtcc atattatgca
      121 caaggaaatc tgatatatgt acgaccgaaa aatacaaatg agattttagt cggagatatt
      181 attacatatt atgaaaattc aggaaaaaaa atctcgacgc gtcgcgtaat agccgttgaa
      241 aacaaccacg aagattttta tacaaaagct gatacaaaga cttatattga gcctggagta
      301 gtaaaaaaga gaaatattat cggtagtccc atctttcaga ttccatatat tggactagtc
      361 ctttcaaaaa cggcatttgc atggattcag gggttattct ttacgattgc tttttgccta
      421 acaggaatca cagcatggaa tacctttgta gagttgaaaa agaagcggag acgaacacag
      481 aaatttttgt aagaatgtta aaaacataaa tgtattccag agatccaacg actcttctga
      541 acatgaaaca cgagaaaaca ctcatgcagc ttgtagattt agtcagttgt tcgtataatg
      601 tgtgaagagg aggagtagta tgcgcaatga aatgatgcat cgtcctgtag tcaaagaaga
      661 actattggat tttatgcgta cccagcaaaa aaaattaccg ggtgagctag gcaaactgga
      721 agaagaagct catgtagcag aagtaccagt tattccccat gaaacagttg tatttttgaa
      781 atttttactt ggacagcttc agcctgaacg aatcttggag atcggagcag ctatcggttt
      841 ttcatcaagt gtcatggcca cgacaatcgg agaaaacgct catgttacga caattgatcg
      901 tttcgatgtc atgatcgaga aagctaaaaa aaactatgaa cgtctaggac tgacagataa
      961 agtgactttg cttgaaggtc aagcagcaga tatcttgccg gagttgtctg gtccgtatga
     1021 ctttattttt atggatagtg caaaatcaaa atatattgaa tttttacctg aatgcttacg
     1081 tttgttaaga aaaggtggcg ttttgatggt agatgacatc ttccaaggag gaacgatctt
     1141 gctcccagat gaagagattc cccgtggcaa acgagctatc catcgtaaat taaatgaatt
     1201 tcttcgtgtt gtgatggatc atcccgattt gacatcgaca atcttgccat taggtgatgg
     1261 tgtgatctta atgacaaagg aatcagaaac aatcgagttg tgatacatga ttatggcagc
     1321 ctgtagataa tcgattgaat cgagggctca attcgaactt gatgtaaaag tttctatatt
     1381 tgtaagtcaa ttaaaggata caggaaatct aaataaacag gagtagcatg aagtcaatgt
     1441 agctcctgtt ttcaattgat aaccttagaa cagctgaagg agaatgtctc gttttaaaag
     1501 attgatttag tagttgggcc aaaataattc attatttgct aattaaataa ctatttcgta
     1561 ttgacagaag caatttaatt atctataatt attgatgttc cgctgattct tgtcatagta
     1621 gctcagctgg atagagcatc cgccttctaa gcggacggtc gggggttcga atccctcctg
     1681 tgacgctaaa aaaccgttag aaactgaggt ttctaacggt ttttctttgt tttttgtgcc
     1741 aatattgttt gttttcaaag gcaaataaaa taaaaaaaca tccttatcga gtacaattat
     1801 aaggagcaaa aaaataaaac tcatcagaaa agaggaagaa gatatgacga tactatctag
     1861 aattttagtg actctagttg caattgaatt tttttatatc atgtatatcg aaacggtgag
     1921 aactgattct gacacgacaa gtagggtttt taaaatgagt aaagaagagt taagcagaaa
     1981 atctgttcaa acattgttta agaaccaagg agtgtacaat ggactattag gagtgggact
     2041 actttatgga gcttatcttt cttccgcatc taaagaaatc acaagtat
//
LOCUS       DAMEEU010000156         2058 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.162, whole genome shotgun sequence.
ACCESSION   DAMEEU010000156 DAMEEU010000000
VERSION     DAMEEU010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.162"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            64..972
                     /locus_tag="PB779_002860"
     CDS             64..972
                     /locus_tag="PB779_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HDE0740334.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKINYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FERWRQEQEHSFQDWREGQESDYLAWFESIKDILKTIDPGGVMLAELTDARVDIQGVR
                     HASISERLLADMDYLYQKLRATLFTIEYGEIEVTDILQDDLFSDNHEVEKVGTVAFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1592
                     /locus_tag="PB779_002861"
     CDS             972..1592
                     /locus_tag="PB779_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740335.1"
                     /translation="MAKTKRMMETDEKTGVQRQFFPITHASAVLGLEEIIAGEATVLS
                     VNGKIGAVVITKEDLGLENVLTELPYASEEDDGIITAEMYQKILNSGEGDYVLPVATI
                     DRLGGIKVGELLTIDETGKVSAVRQSDVNFSLELKEKLDSLKNYTAGENITIDEDGTI
                     SSTGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1596..2045
                     /locus_tag="PB779_002862"
     CDS             1596..2045
                     /locus_tag="PB779_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740336.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTTVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKAKLDGLANITFEKVGTV"
BASE COUNT          728 a          315 c          467 g          548 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taagaataca gaggttatgg aagcgactat agttgaaaat
      181 ggtcttccct acgatttatc agaatgtaag gtatattttg aatcagttgt aggtgggaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat taactatatt
      301 tttgataaat attccatgca gtgtttacat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcattaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaatcg aagatttaat tgcggatatg
      481 acggacttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgaac gttggagaca agaacaggaa cacagtttcc aagattggag agaaggacaa
      601 gaatcagact atttggcatg gtttgaatca atcaaggata ttttaaagac gattgatcca
      661 ggtggagtca tgttagccga actaacggat gcgcgagtag atattcaagg agttcgtcat
      721 gcgtctattt cagagcgttt gctggcagat atggactatt tatatcagaa attgcgagca
      781 acgcttttca cgattgaata cggggagatt gaagtgactg atattttgca ggatgatctc
      841 ttttcagata atcatgaagt cgaaaaagtt ggaactgtag cattcccgat tgaagaagga
      901 gccttgatca tcgcaaccgt tgatgatcca aagcaaaatg tgttcactct tgagaaagtt
      961 ggggtgatct aatggctaaa actaaacgaa tgatggaaac ggatgaaaaa acgggtgtac
     1021 aacgccaatt ctttccaatc acacatgctt ccgcagttct tgggttagaa gaaataatag
     1081 caggagaagc aacagtttta tctgttaatg gaaaaattgg agccgtcgtc attactaaag
     1141 aagatttggg attagagaat gttctcacag aattacccta tgcaagtgaa gaagatgacg
     1201 gcattatcac ggcagaaatg tatcaaaaaa ttttaaacag tggagaaggt gactacgtgt
     1261 tgccagttgc cactatcgac cgtttgggtg gcataaaagt tggtgaatta ttgacgattg
     1321 atgagacagg gaaagtctct gcagtcagac aatctgatgt caatttttcg ctggagttaa
     1381 aagaaaaact cgattcactg aaaaattata ctgctggaga aaacatcact attgatgaag
     1441 atggaacaat tagttctaca ggtggtagtg ggactggtgg tgtcaatcag tcatatgtag
     1501 atcaaaaatt ccaagaagct gtaaatcaag cagaaaatta cacaaacgaa agaattccaa
     1561 attttacttt tgaaaaaatt ggggaggtat agagaatgac agatatcgta aaaataaaac
     1621 aaagcaatgt acaggtttat ccacaaactc attggaatgc tatagaaggc aaaccaacaa
     1681 cggtgaaggg agataaaggc gatcctggcc aagcagcaac aattaccata ggaaccgttt
     1741 ctagtggttc aaccgcttct gttacgaatg taggaacatc atctgcagct agatttaatt
     1801 ttgttttacc aaagggagat aaaggtgatc ctggaataaa tgccacaact acagctgtag
     1861 ctacaactac agcaaatggg ttgatgtcgt ccacagataa aactaagttg gatggaattg
     1921 cagctggagc acagaaaaat ccaggtaatg ctacaactac gacagcaggt ttaatgtcag
     1981 caactgacaa agctaaactc gatggattag ccaatattac atttgagaaa gtggggacgg
     2041 tttaatggct gatattgt
//
LOCUS       DAMEEU010000157         2057 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.163, whole genome shotgun sequence.
ACCESSION   DAMEEU010000157 DAMEEU010000000
VERSION     DAMEEU010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2057)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2057)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2057
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.163"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(169..242)
                     /locus_tag="PB779_002863"
     tRNA            complement(169..242)
                     /locus_tag="PB779_002863"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Ile,seq:cat)
     gene            complement(431..1450)
                     /locus_tag="PB779_002864"
     CDS             complement(431..1450)
                     /locus_tag="PB779_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HDE0740337.1"
                     /translation="MKKKITITAMSLLTALFLLPINGFAYTINNEFNLGANEGSSQVA
                     NNQYILLHETANETATGRNEAQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGS
                     YANANSPVQIELQHTHDKATFEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHL
                     WVTQNIWGDHTDPYGYLSEMGVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAAN
                     PTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIY
                     RADVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYL
                     NIPKR"
     gene            complement(1447..1671)
                     /locus_tag="PB779_002865"
     CDS             complement(1447..1671)
                     /locus_tag="PB779_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HDE0740338.1"
                     /translation="MNNKTFEVLKWFALVIIPALATFVGLVGKALNWQYTDICVVIIT
                     GFGAFLGSVLGVSNRTYKMFSAESEEGGNK"
     gene            complement(1668..1961)
                     /locus_tag="PB779_002866"
     CDS             complement(1668..1961)
                     /locus_tag="PB779_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740339.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKTLFRERRK"
BASE COUNT          602 a          421 c          350 g          684 t
ORIGIN      
        1 aaaacttttc aaatatacag aaatataact atgtgaaaca tcctttcatt aatccataaa
       61 aggatacata aaaaagccac tcatttgagt ggcaatgaag aaaagcttta gcttgtataa
      121 tactcttcaa aaaattctaa cacagaacga ttcaaatggc tacgttaatg taccctgtag
      181 gactcgaacc tacgaccgga cggttatgag ccgtctgctc tgaccaactg agctaagggt
      241 actggttgtt gccacataaa gccataaaca atcaaccagt agaatgtgtg gcaacaaacc
      301 tgttatcgca tagcttggag tgtgactatt atgggtgata gtgaagatat gcgataacat
      361 cactatttta tcgaatgatt tttatagttg tcaatatagt tatgtaatgc tcctcaacga
      421 ggagctattt ttatcgttta ggaatattta aataccaacg tttgtcatgg aaatcttgcg
      481 caccgccttt agtgtttccc tctggatcat tcgttgcccg catcatgaca tagactttct
      541 tattagggaa gttacgcatg ttaaaagata catgatagcc aacatttcca gaagtattat
      601 aagcttgatt tacatctgct ctataaattc catcagctct tactcgagct aattctttcc
      661 cagtattgta atccataatg aagatatact cgtatttata gttagcaatg tgccatccag
      721 ctacatgcaa atttgcattt tcgatttctc caaactgatc aatgtgggcg taattcgttc
      781 catctgtcag tgtaggatta gctgcaccag ctcgtgttgg atcaatgaca ggcttgtttt
      841 cagaagttgt tggattttca tcggtaaatc catgagctaa atcatatgct aatttttctt
      901 tacttacgcc catttcagaa agataaccgt aaggatctgt atgatcgccc cagatgtttt
      961 gtgttaccca taaatgcgat ttgattcccg gttggttata aggagtgtcc aacgttaatg
     1021 gaataccata tttcattgct gaatctctag ccaattcaac gtatgccttg tagtttttct
     1081 caaacgttgc tttatcatgt gtgtgttgta actcaatctg cacaggactg ttggcattag
     1141 catacgaacc agcaccgtac tgtacataac caggttgacc gacttgataa acaattccgc
     1201 cgtctcccac aatataagca gtataagcgc tagtccatga acgttgcata tactgcgctt
     1261 cattgcgtcc tgttgctgtt tcattagccg tttcatgcag taaaatatac tgattatttg
     1321 ctacttgtga gctaccttca tttgcgccca aattaaattc attgttgata gtataggcaa
     1381 atccgttaat tggcaataaa aaaagagccg ttaacaggct catcgcagta atagtaattt
     1441 tctttttcat ttgtttcctc cttcttcgct ttcagccgag aacattttgt aggttcgatt
     1501 tgatacaccc aacacactcc ctaaaaacgc gccaaaacca gtaatgatga caacacagat
     1561 atctgtgtac tgccaattga gcgctttacc aactaacccc acgaaagtag ctagtgcggg
     1621 aataattacc agtgcgaacc attttagtac ttcgaacgtt ttattattca ttttcttctc
     1681 tccctaaaca aagttttgat ttgttgcgtg tgttccacca atttttctgt atgtgtatct
     1741 aatctttcat cgtgtttctt tagttcttca tgaatcatca atcgatctga tttgctcgat
     1801 tctaaatctt tagtcagcaa atctaaattg tggcttactt ttgaaagagt ctcagtaatt
     1861 ttcgagaaag atgcagcaat cggtctaatt actaataaaa tcaaagaaac gatagcggtt
     1921 attgatcctg ctatcattcc ccattcccct aaattaatca tgtgacaact cctttacctt
     1981 aaataaaaac gcatcaatta agatgcgctc ttatctttat taatgatttt atctgcttct
     2041 tcgtctgtaa tgcataa
//
LOCUS       DAMEEU010000158         2055 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.164, whole genome shotgun sequence.
ACCESSION   DAMEEU010000158 DAMEEU010000000
VERSION     DAMEEU010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2055)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2055)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2055
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.164"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            64..972
                     /locus_tag="PB779_002867"
     CDS             64..972
                     /locus_tag="PB779_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HDE0740340.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKIKYIFDKYSMQCLHRQTANFIIFKGED
                     LIGTTQDFSYFVINAVSKTEGEMGSYWQSIEDLIADMTDFINENKGDFTDWMNERKEE
                     FDRWREEQENSFQDWREGQESDYLSWFESIKDILKSIDPGGVMLAELMDARVDLQGVR
                     HESISERFLSDLNYLYQKMKAALFTIEYGEIEVTDILQDDLFSDNHEVEKIETVEFPI
                     EEGALIIATVDDPKQNVFTLEKVGVI"
     gene            972..1589
                     /locus_tag="PB779_002868"
     CDS             972..1589
                     /locus_tag="PB779_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740341.1"
                     /translation="MVKVKRMMETDESGVKRQFMPITHVSAVLGLEKMISGQSKVLSV
                     NGKYGAVILTKADLGLENAITELPYASETSDGILTAEMFQKIVNGEGGTYILPIATPE
                     QLGGIKVGELLEVTEEGVLSATKQTDFNFSEELKGKLESLKILKAGANISIAEDGTIS
                     STGGSGTGGVNQSYVDQKFQEAVNQAENYTNERIPNFTFEKIGEV"
     gene            1593..2042
                     /locus_tag="PB779_002869"
     CDS             1593..2042
                     /locus_tag="PB779_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740342.1"
                     /translation="MTDIVKIKQSNVQVYPQTHWNAIEGKPTMVKGDKGDPGQAATIT
                     IGTVSSGSTASVTNVGTSSAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDK
                     TKLDGIAAGAQKNPGNATTTTAGLMSATDKVKLDGLANITFEKVGTV"
BASE COUNT          746 a          291 c          440 g          578 t
ORIGIN      
        1 cagtattata gtgcaagtgc aatttcttcc attgtcatac caccaaaata gggaggtgat
       61 ttaatggcaa agtggaatgt catattaagt acaacagaac cctataatta cgtggggatg
      121 attcaagttc gacaaggcaa taaaaacact gaagttatgg aagctacaat tgtcgaaaat
      181 ggtcttccat atgatttatc agaatgtaag gtatattttg aatcagttgt tggcggaaaa
      241 tatccagtcc aattagaaac aaaaattgtg gatgctaaaa aagggaaaat caaatatatt
      301 tttgataaat attccatgca gtgtttgcat cgacaaacag ccaatttcat tatatttaaa
      361 ggagaagact tgattggaac aactcaagac ttctcttatt ttgtcatcaa tgctgtttca
      421 aaaacagaag gagaaatggg ttcttattgg caatcaattg aagatttaat tgctgatatg
      481 acagatttta ttaatgaaaa taaaggcgat tttacggact ggatgaatga aaggaaagaa
      541 gaatttgatc gctggagaga ggaacaggag aatagtttcc aagattggag agaaggacaa
      601 gaatcagatt acttgtcatg gtttgaatca atcaaggata ttttgaagtc tatcgatcca
      661 ggtggagtaa tgttagccga attaatggat gcacgtgtag atcttcaagg tgtacgccat
      721 gaatcgattt ctgaacgttt cctatccgat ctaaattatt tgtatcaaaa aatgaaagca
      781 gcacttttca cgattgaata cggtgaaatt gaagtgactg atattcttca agacgatctc
      841 ttttcagata atcacgaagt cgaaaaaatt gaaacagtag aatttccaat tgaagaagga
      901 gctttgatta ttgcaactgt tgatgatcca aaacagaatg ttttcactct tgagaaagtt
      961 ggggtgattt gatggttaaa gtaaagagaa tgatggaaac tgatgaatct ggtgttaaac
     1021 gtcaatttat gccaattaca catgtctctg cagttttagg cttagaaaaa atgatatcag
     1081 gacaatcaaa agttctttcg gttaatggta aatatggtgc agtcatttta acgaaagctg
     1141 atttaggatt agagaatgca attactgaac taccttatgc aagcgagaca agcgatggta
     1201 ttcttactgc tgaaatgttt caaaagatcg taaatggaga aggtggaaca tatattttgc
     1261 cgattgctac tcctgaacaa ttaggaggta taaaagttgg ggaactctta gaagttactg
     1321 aagaaggtgt tttatctgca actaagcaaa cagacttcaa tttctctgaa gaattaaaag
     1381 gaaaattaga atctctaaaa atattaaaag caggtgcaaa tatatcaatt gcagaagatg
     1441 gaacaattag ttctacaggt ggtagtggga ctggtggtgt taatcagtca tatgtagatc
     1501 aaaaattcca agaagctgta aatcaagcag aaaattacac aaacgaaaga attccaaatt
     1561 ttacttttga aaaaattggg gaggtataga gaatgacaga tatcgtaaaa ataaaacaaa
     1621 gcaatgtaca ggtttatcca caaactcatt ggaatgctat agaaggcaaa ccaacaatgg
     1681 tgaagggaga taaaggcgat cctggccaag cagcaacaat taccatagga accgtttcta
     1741 gtggttcaac cgcttctgtt acgaatgtag gaacatcatc tgcagctaga tttaattttg
     1801 ttttaccaaa gggagataaa ggtgatcctg gaataaatgc cacaactaca gctgtagcta
     1861 caactacagc aaatgggttg atgtcgtcca cagataaaac taagttggat ggaattgcag
     1921 ctggagcaca gaaaaatcca ggtaatgcta caactacgac agcaggttta atgtcagcaa
     1981 ccgataaagt gaaacttgat ggattagcga atattacatt tgagaaagtg gggacggttt
     2041 aatggctgat attgt
//
LOCUS       DAMEEU010000159         2013 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.165, whole genome shotgun sequence.
ACCESSION   DAMEEU010000159 DAMEEU010000000
VERSION     DAMEEU010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 2013)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2013)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2013
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.165"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            272..838
                     /gene="amaP"
                     /locus_tag="PB779_002870"
     CDS             272..838
                     /gene="amaP"
                     /locus_tag="PB779_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HDE0740343.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            851..1039
                     /locus_tag="PB779_002871"
     CDS             851..1039
                     /locus_tag="PB779_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HDE0740344.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            1052..1609
                     /locus_tag="PB779_002872"
     CDS             1052..1609
                     /locus_tag="PB779_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HDE0740345.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            1641..1883
                     /locus_tag="PB779_002873"
     CDS             1641..1883
                     /locus_tag="PB779_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HDE0740346.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
BASE COUNT          736 a          309 c          407 g          561 t
ORIGIN      
        1 ataaatagaa tcttgtaata ataactgagc ataatctttg caatttttaa tcttgaataa
       61 tatcctttaa gtatagccag caatcaaaag taaatagaga ataagtaagc aattgttatt
      121 tcagtatcag actggcaata aaacgccgtt atgatccagc aatgtttggt agcgctttat
      181 ttactgatgc tatgctaact gttcgctatc tatactgtga ttgtcggtag agttatttac
      241 agggtaaaaa taagtttata ggaggtggaa aatgaataag gggttaaaaa taatcggtgt
      301 tatcatgagt ttactgctac tttcagtatt tctagcgatt gcgttgatca atgcgccgta
      361 tattatgcct gaacaattgg aacgatttcg cttctttact ttaacgaatt actacatgca
      421 acaatatatt ttctgggcag ctgtagtatt tgccgttctt gctattatca tcttgctagt
      481 cgttcttttc tatccaaagt caagaggaac tttcgttatg aaacgggaag atggcaaact
      541 aacaatcgac aaaaaagcga tcgaagggtt ggtacgttcc catttacacg aagaagagtt
      601 cattcattca cctaaagtac ggatacgttc aacgaaaaat cgaatccata tccatgtcaa
      661 cggagacttg aaacgaactt cttcattagt agggaaaaca ggtgtattga tgcaagatat
      721 cgaagaagaa gtaactaaag tactcggaac aaaagaaacg gtcaaagtgg cagtcacata
      781 cagcggttat gaagaacaag aagatacaag agactacaag cactctcgag tggaatagga
      841 gggccaaata atgaaagaac tattttcagc atacaagctc cctattatct ttgggggtct
      901 tggactactg ctagctgttt tatggttaac gattggattt ttcaagacat tgttgatcat
      961 aatcatgaca gcaattggcg caggaatcgg tttttatttg aaacagtcag gaatagttga
     1021 tcaatttttt aaatcatagg aggaaacaaa gatggaaaac aaaaacatga atacaacaaa
     1081 tggatcagtt ttggcaaatg aaaaaggaga aaaccgcatg atgaatggtg aattgactta
     1141 tgaagacaaa gtcatccaaa aaatcatcgg ttatgcattg aaagatgtag atggtctatt
     1201 gacattagat ggcggatttt tctcaaatat ggctgaaaaa ttagtcaaca cagataacgt
     1261 aacagcaggt atcaatacag aagtaggtaa gaaacaagta gctgtggatc tagatgtgat
     1321 cgtagaatac ggtaaagaca tcgaagatat ttacaaccaa atcaaagaat tgatcagtac
     1381 tgaagtaaac aatatgacac atttagatgt tatcgaagtg aatgtgaatg ttgcagacat
     1441 caaaacacaa gaagaatacc aaaaagatca agaaacagta caagacaaag taacagaagc
     1501 agcaaaatcc acaggacaat ttgcttcacg ccaaacagat aaagcaaaat ctgctgtagg
     1561 caaaggtgca caaaaagtca aagaaaataa cgaaccacgt gtacaataag aagtaagaag
     1621 tcagttagga ggaatttaaa atgggattta tttgggcatt aatcgtcggc ggtatcattg
     1681 gagcaattgc aggagcaatc acgaataaag gatcatcaat ggggatcatc gcaaacatca
     1741 ttgctggttt agtaggttca gcaattggac aagctttact aggaacttgg ggaccaacaa
     1801 ttgcaggaat ggctatcatt ccatcattga tcggtgcaat cattttagta ttagtcgttt
     1861 cattctttgc acgtaaatta taagcaaatt gaagaaaaac ttatgttgaa atgaagaaca
     1921 aatttgagaa ccgtagcgac actcgctgcg gttctttttt atatatttta tatgaagtat
     1981 tctttattcc ttatgaaaaa atatctttaa aaa
//
LOCUS       DAMEEU010000160         1870 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.166, whole genome shotgun sequence.
ACCESSION   DAMEEU010000160 DAMEEU010000000
VERSION     DAMEEU010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.166"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..505
                     /locus_tag="PB779_002874"
     CDS             <1..505
                     /locus_tag="PB779_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740347.1"
                     /translation="IQSIFGIEEVFVGDKCIFFDQPLLSDGYGIDETDIFAKVNSIFS
                     GKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTLLISPISTISFSPSMM
                     FEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLSEEKILLPENWAELRK
                     LVEYGII"
     gene            492..>1870
                     /locus_tag="PB779_002875"
     CDS             492..>1870
                     /locus_tag="PB779_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDE0740348.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIY"
BASE COUNT          609 a          240 c          286 g          735 t
ORIGIN      
        1 catacaatca atctttggga tagaagaagt ttttgtcgga gataaatgta tcttttttga
       61 tcaaccttta ttatctgatg gttatggcat agatgaaaca gatattttcg ctaaagtaaa
      121 tagtatattt tctggaaaaa aagaaacttt aattaagctt catcctagag caaggacaaa
      181 tcgttatggt gaaaaaaaca tattgaattc cagtttaccg tttgaagtct tgctacttga
      241 aaatgacttc tcttcaacac ttttgattag tcctatatct acaatttctt tttcaccatc
      301 tatgatgttt gaaaagacga tcaactctat tatgttggct aaattaattt taaatgaata
      361 tacagcatta tctgaagata aaaaagaaac attgacaaat attgttcttt tctgtgaaca
      421 ttataaccgt ctatcagaag aaaaaatttt actcccagaa aactgggcag aattaagaaa
      481 gttggtagag tatgggatta tttaacacac tttccaagtc aaaattagtt aagtccagtt
      541 tctggtatac tatagggaat ttttttatta agggaatttc attcataact attcctattt
      601 ttgtaaatat tactactcaa gcagaatatg gtttgattaa taatttcact tcatttgtat
      661 caattttttc gattcttgtt gggctaagcc taaattcggc aattaataat gcaagttttg
      721 actataaaga tgacataaat gaatttatgt catcggtact ttctctagct acactttcgt
      781 taattgtgtt cttattaata gggaacatat attttttgtt ttcaaatgct ttttttgata
      841 tgaaccaact tgtatttaat ttgatgttat tacaaagttt tgctagtttt gtaattagtt
      901 atatccagtc ttattttacg attaacttta accattttaa atatttgatt ttatctttta
      961 tatctacttt tttgaatatt gcaatctctg tagctttgat gcagacatta tattttgatg
     1021 ataaatatgt tggcagagta gtcggcggaa cactgtcatt tgtgttgata ggtttagtaa
     1081 tttatttaag aataatgata aagggtgctc atttttttga taaaaaacag tggagatacg
     1141 ctttaaaaat ctctttgccg ctaatcccac attccttagc aaatatagtt ttagcacaat
     1201 tcgatagaat tatgattaat tcttatttag gtcctgctgc ggggggaata tattcctaca
     1261 ttagtaacat aggtattatt ctaagcgtaa tatggatgtc tactaataac gcctgggttc
     1321 catggttcta tggtgagatg agtaaaaata atgaaaaaaa agtgaagaaa gttagtaact
     1381 attatttagt agtctttact ttgattacga tgattgtaat ggtagtttcg attgatttag
     1441 caaaatttat ggctccgaaa gactattatt ctgggttatc tttagtggtt ccgataacct
     1501 taggctattt ctttcagttt ttatatagtt taccagttaa tgctgaattt tatgagaaaa
     1561 aaacatcgtt tattgcgatt ggtacagtag caagtgctat agttaatata ctattaaaca
     1621 tgattttcat acctaggtta ggaataattg ctgctggata cacaaccgta tttacgtatt
     1681 ttttactttt tatttttcat tataatatcg ctaaaaaaat tacgaataaa caattatttg
     1741 acacaaaaaa aatatgtatc ataataattt ttgtatcaat tttttctttg atacttcata
     1801 ttttaatcaa tcaaatgttg attcgttacg ttttgacatc attattgata attagtttag
     1861 ttatatattt
//
LOCUS       DAMEEU010000161         1855 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.167, whole genome shotgun sequence.
ACCESSION   DAMEEU010000161 DAMEEU010000000
VERSION     DAMEEU010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1855)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1855)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1855
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.167"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..535
                     /locus_tag="PB779_002876"
     CDS             <1..535
                     /locus_tag="PB779_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740349.1"
                     /translation="TIQIPLVTAGSRTALQLSDIFNPMIDIYKEKKYIFFTSVYDFEG
                     GEPVGEYELVCKIADLVGKDNLIVKTHPRDVRTIYKDNGFIEDKNSSIPWEAIQLSGD
                     FNDKIFMTINSGSVISGSTMSAKPVRTYYMYKLCNIEGNPSCKKNAYDIERLLKQKTM
                     KNILKNVKIAESLDDIL"
     gene            532..>1855
                     /locus_tag="PB779_002877"
     CDS             532..>1855
                     /locus_tag="PB779_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HDE0740350.1"
                     /translation="MSKTKYLIKNMGILTISNFSSKILVFLLVPLYTSVLSTTEYGTY
                     DLTISTATLLFPILTLNIVDAVMRFLMDKDKNKKNIASIAIKVIFLSVIVFGSVMYLL
                     NITKLWQDVYGLEKYIFLYYISYVWNQFLIQFAKGLEKVKAMGIAGIISTIVTIIANI
                     FFLLILKWGLIGFFIANILSQIISATYLSVLVRIWEYIDFEAKDPQLKREMLNYSIPL
                     IATVVGWWINSTADRYVVSFIVGVSANGLLSVAYKIPQIINTLQGIFIQAWQISAIKE
                     YGDNETAKFYGNTFVMINLLMCITCSSLIILTRPFSHILYAKDFYEAWKYVPFLLIAN
                     VLNCASGLLGPILSAKKDSKSMMWSAIIGALVNVIMSVVLVYKIGVQGATIATVICSY
                     VIYVVRKRAVGKDIFIKHYHIVVESWGLLFVQAIIEIYFKNYVIEIIIM"
BASE COUNT          652 a          221 c          331 g          651 t
ORIGIN      
        1 tacaatacaa attccattag ttacagctgg gtcaagaacc gcattgcaac tttcggatat
       61 ttttaaccct atgatagata tttataaaga aaaaaaatat atatttttta cgtctgttta
      121 tgattttgag ggcggagaac ctgtcggaga atatgaatta gtatgcaaaa tagcagactt
      181 agtaggaaaa gataatctaa ttgttaagac gcatcctaga gatgtaagaa caatttataa
      241 agataatgga tttatcgagg ataaaaattc atcaatacct tgggaggcga ttcaattgtc
      301 aggcgatttt aacgataaaa tatttatgac aattaattca ggaagtgtta tttcaggtag
      361 tacaatgtct gcaaaacctg tacgcacgta ttatatgtat aaattgtgta acatagaagg
      421 aaatccgtct tgcaaaaaga atgcgtatga tattgagcga ttgcttaagc aaaaaacgat
      481 gaaaaacatt ttaaagaatg tgaaaatagc agaaagctta gatgatatac tatgagcaaa
      541 actaaatatt taattaaaaa tatgggaata ttaacaataa gtaatttttc ttcaaaaatt
      601 ttagtttttt tgttagtccc tttatataca agtgtattat ccacaacaga atatggcaca
      661 tatgatttga caatttcaac agccacatta ttgtttccaa ttttaacctt aaacattgta
      721 gatgctgtga tgcgcttttt aatggataaa gataaaaata aaaaaaatat agcatctata
      781 gcgattaaag ttatattttt aagcgtgata gtctttggat ccgtaatgta tttgttaaat
      841 attacaaaat tatggcaaga tgtttatgga ttagaaaaat atattttttt gtattatata
      901 tcctatgtat ggaatcaatt tctaatacaa tttgctaaag ggttagaaaa agttaaagct
      961 atgggcatag caggtattat cagcacaatt gtaacaataa ttgccaatat tttcttcttg
     1021 cttattctga aatggggatt aattggtttt ttcattgcaa atattttatc acagattatt
     1081 tcagctactt atctgtcagt attagtgaga atatgggaat atatcgattt tgaggctaaa
     1141 gatcctcagc taaagagaga aatgctaaat tactcgattc cattaattgc aactgttgtt
     1201 ggatggtgga ttaatagtac agctgatagg tatgtggttt cctttatagt aggtgtctcg
     1261 gcgaatggct tattgtctgt ggcatataaa atacctcaaa taattaatac tttgcaggga
     1321 atatttatac aggcctggca aatttctgca attaaagaat atggagataa tgagactgca
     1381 aaattttatg gaaatacatt tgttatgatt aatttgttaa tgtgcataac ctgttcaagt
     1441 cttatcatat taactagacc gttttcacat attctttatg cgaaagactt ttatgaagcg
     1501 tggaaatatg ttccattttt attaatagct aatgttttaa attgtgcatc aggtctgtta
     1561 ggacctatct tatcagcaaa aaaagattct aaatccatga tgtggtctgc aatcataggg
     1621 gcattagtta atgtgattat gagtgtagtc cttgtttata agataggggt tcaaggtgcc
     1681 acaatagcca ctgttatatg ttcatatgta atatatgttg ttcgtaaacg agctgtggga
     1741 aaagatattt ttataaagca ttatcatatt gttgtggaat cttggggatt attgtttgtt
     1801 caggcaatca tagaaatata ttttaaaaat tatgtaatag aaattataat tatga
//
LOCUS       DAMEEU010000162         1850 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.168, whole genome shotgun sequence.
ACCESSION   DAMEEU010000162 DAMEEU010000000
VERSION     DAMEEU010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1850
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.168"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            141..440
                     /locus_tag="PB779_002878"
     CDS             141..440
                     /locus_tag="PB779_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740351.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(476..847)
                     /locus_tag="PB779_002879"
     CDS             complement(476..847)
                     /locus_tag="PB779_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740352.1"
                     /translation="MFDFNEYLSISKQIESDDKYNSKESYRRTAVSRAYYSAFKKSDE
                     YLKENYDIIYNGSSGKGSHQTVWNLFSTVKELNTLGIHNSGYRMLEKRKCADYIPNET
                     ITKTDMALMNREAEKIINKLT"
     gene            complement(849..1250)
                     /locus_tag="PB779_002880"
     CDS             complement(849..1250)
                     /locus_tag="PB779_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740353.1"
                     /translation="MLDIVPSNTHRSGSLINFAAIFACASVILASPVVVDASSTPKTK
                     NDNQLVITTKNEINTISSNDGKIFDVINTVLKRKAEINIKYDEDLNLYFFVIKTTSEL
                     FSSDYDVLDTLDNVLSDYKYMGKSVVATLGE"
     gene            complement(1264..1671)
                     /locus_tag="PB779_002881"
     CDS             complement(1264..1671)
                     /locus_tag="PB779_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740354.1"
                     /translation="MSYRVQLIISEDVESQQFGTNVINKVINPALSINAPLIPTALSF
                     SVTAVVSEIEDTEKIKIVEIEVLNKNEKQIFSTGEVSVSLPPQVNDINFNINARNVLV
                     EEAGEHYAVVKFNGTEIGRQIFDIKVNKPVEKN"
BASE COUNT          609 a          302 c          255 g          684 t
ORIGIN      
        1 attttagcta tattagcttt ttccgaaaat aaacaacctg taactgcaaa aaaagaaaca
       61 gtattctctg aaggcaaaat aaaaactcga tatatattag aggtagagac taagtttaaa
      121 aatagatcgg agtaatggtt atgcttttta atgagacgca attatggttt aaatttgatc
      181 cttcgaatag atttgtcaaa gatttttata aggtgtggga ttcagaagtt ttctttttag
      241 caatcgaaga tagcttatta attaatctct actattctaa taagaactac tttaaaatcc
      301 ctgctgcgaa aactagaatg aagaaagacg tatatttttt gtttgatatc gtgactgatg
      361 tgccggacgc acgtagcgat catcggcgtt atgactatat aaagtatact ttcgttgatc
      421 cagaaagata caaagattaa ataaaaaaat aacaaacaaa ctcgcttgaa attcattagg
      481 tgagtttgtt tattattttt tctgcttctc gattcatcag cgccatatct gttttcgtaa
      541 tggtttcatt aggaatatag tcagcacatt ttcttttctc taacattcta tacccactat
      601 tatgtattcc taaggtattc aattccttaa ctgttgaaaa caaattccaa acggtttggt
      661 ggcttccttt tccgctactt ccattataaa taatatcata attttctttc aaatactcat
      721 cagatttttt aaaagcactg tagtatgctc ttgaaacagc agttcttcta taagattctt
      781 tagaattata tttatcatct gattcaattt gtttggaaat agataaatat tcattaaagt
      841 caaacatttt attcccccaa agttgctact acagatttcc ccatatattt atagtcagat
      901 aatacattat cgagagtatc caaaacatcg taatctgagg aaaacaattc agatgttgtt
      961 ttgataacaa agaaatacaa gtttaaatct tcatcatatt ttatattgat ttcagctttt
     1021 ctttttaaaa ccgtatttat cacatcaaaa attttgccat cattacttga aattgtgtta
     1081 atctcatttt ttgtagtaat tacaagttga ttatcatttt tagttttcgg agtagaactt
     1141 gcatccacaa caactggaga tgctagaatt accgatgcgc aagcaaaaat cgcagcaaaa
     1201 tttattaagc taccactccg atgtgtattt gatggtacta tatcaagcat ccgtatcgtc
     1261 tccttaattt ttttccactg gtttgttgac cttgatatca aagatttgcc ttccaatctc
     1321 agttccatta aatttaacaa cagcataatg ctctcctgct tcttcaacca agacatttct
     1381 ggcgtttata ttaaagttta tatcgttaac ttgaggaggc aagcttaccg atacttcacc
     1441 cgtagaaaaa atttgttttt cattcttgtt taaaacttca atttctacta tttttatctt
     1501 ttctgtatcc tctatctcag acaccacagc tgttacagaa aatgataaag cagtaggaat
     1561 taaaggcgca ttaatagaaa gagctggatt aattacttta ttaataacat tagtgccaaa
     1621 ttgctgactt tctacatctt ctgaaattat taattgtact ctataagaca ttgatttctc
     1681 ctaattttta catttattta ataaatttat gtttcacttt tgctagtcaa tttagtttaa
     1741 caatagtaac aaagctttgt caacggaaat attagctaat tttgtaagca tatttataag
     1801 tatatttgta agcatatctg acatttaatc agtagtaaaa gtgcctctat
//
LOCUS       DAMEEU010000163         1758 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.169, whole genome shotgun sequence.
ACCESSION   DAMEEU010000163 DAMEEU010000000
VERSION     DAMEEU010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1758
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.169"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..1397
                     /locus_tag="PB779_002882"
     CDS             <1..1397
                     /locus_tag="PB779_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HDE0740355.1"
                     /translation="GGTVDLTDNVTNLPTLPEGTTVTDVTPGGTIDTNTPGNYEGVIE
                     VTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEVGGTVDLTDNVTNLPTLPEGT
                     TVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYTPMVEGE
                     KVEVGGTVDLTDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDGTKDT
                     VKVPVEVTDNRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYTWKEKVDV
                     STAGNKKGIVVVTYPDGSKEEVEVTISVEDKKAPNKPQVDPITEGDQIVTGKTEPNAE
                     VTVTLPNGSQYHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNVVVSSNEK
                     DSEKAVSKDNKTDNQGSKQNKNRGKSSPQKQSSKAYPKTGEIDSNIFTISGGLILLGT
                     LGLLGYKNRKKENE"
     gene            1531..>1758
                     /locus_tag="PB779_002883"
     CDS             1531..>1758
                     /locus_tag="PB779_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HDE0740356.1"
                     /translation="MKKIVIIGSNHSGLAAARFLNLCDSNYEVILIDKKSEISYLECG
                     TSLFIKREVSNLEDLFYQNRRELNSKIKKLFL"
BASE COUNT          688 a          262 c          372 g          436 t
ORIGIN      
        1 ttggaggcac agtagatcta acagataatg ttactaactt gccaacatta ccagaaggaa
       61 caacagtaac agatgtcact cctggtggta cgattgatac caacacacca ggtaattacg
      121 aaggggttat cgaagtaacg tatccagatg gtacgaaaga tacagtgaaa gttccagtag
      181 aagtgacaga caatcgttcc gatgccgata aatatgaacc aacagtagaa ggcgaaaaag
      241 tagaagttgg aggcacagta gatctaacag ataatgttac taacttgcca acattaccag
      301 aaggaacaac agtaacagat gtcactcctg gtggtacgat tgataccaac acaccaggta
      361 attacgaagg ggttatcgaa gtaacgtatc cagatggtac gaaagataca gtgaaagttc
      421 cagtagaagt gacagacaat cgttctgatg ccgataaata tacaccaatg gtagaaggtg
      481 aaaaagtaga agttggaggc acagtagatc taacagataa tgttactaac ttgccaacat
      541 taccagaagg aacaacagta acagatgtca ctcctgatgg tacgattgat accaacacac
      601 caggtaatta cgaaggggtt atcgaagtaa cgtatccaga tggtacgaaa gatacagtga
      661 aagttccagt agaagtgaca gacaatcgtt ccgatgccga taaatacaat cctgaaggac
      721 aaaaagtgac tacagactta aataaagagc cagacgcatc tgagggaatt aagaacaaag
      781 aagatctacc aaaaggaact acttatactt ggaaagagaa agtagatgtt agtacagctg
      841 gaaacaaaaa agggattgta gtagtaacat atccagatgg atctaaagaa gaagtagagg
      901 ttactatttc tgtagaagat aaaaaagcac cgaataaacc tcaagttgat cctattacag
      961 agggtgacca aattgttact ggtaaaactg aaccaaatgc agaggtgaca gttacattac
     1021 caaacgggag tcaataccat gggacagctg ataaaaatgg taattttaca gttaaagttc
     1081 ctaaattaga ggcaggaaca aaagtgatag taactgcaac tgatgaatct ggtaatacta
     1141 gtgaacctac taatgtagtt gtttcttcaa acgaaaaaga cagtgaaaaa gccgttagta
     1201 aagataataa gactgacaat caaggtagca agcaaaacaa aaatagaggc aaaagcagtc
     1261 ctcaaaagca gtcctcaaaa gcttatccta agacgggaga gattgatagt aatatcttta
     1321 ctattagtgg tggtttaatc ctgttaggaa ctttagggtt attagggtat aaaaatcgaa
     1381 aaaaagagaa tgaatagaaa atcaatttct taaatcttct ctgaaaagag gaagaatctt
     1441 tttcttcctc tttttgtttt ttattttggg agataggttg ttagttaaaa atgaagatac
     1501 ttttcataga agggaaaaga atgtgattaa gtgaaaaaaa tagtaattat tggatcaaac
     1561 cattcggggc tagctgcagc tcgatttcta aacttatgtg attcaaatta tgaagttatt
     1621 ctgatagata aaaaatcaga aattagttac ttagaatgtg ggacatcgtt gttcataaaa
     1681 agagaagtta gcaatttaga agatcttttt tatcaaaata gaagagaact aaattctaag
     1741 ataaaaaagt tgtttttg
//
LOCUS       DAMEEU010000164         1740 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.170, whole genome shotgun sequence.
ACCESSION   DAMEEU010000164 DAMEEU010000000
VERSION     DAMEEU010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1740
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.170"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            143..1690
                     /locus_tag="PB779_002884"
     CDS             143..1690
                     /locus_tag="PB779_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HDE0740357.1"
                     /translation="METTDTLLQLLQEAHKTNQAQQQTIQNLTTEIQLLNEKVNYLTN
                     KLFGRSKETLFEETNGQLNLFSDEEISVSVPEAAATIIPVKGHQRVVGTKADKIKHLP
                     ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCLTHYQHTYCCKSCEK
                     EGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQENYWKQTHGLDISRD
                     NITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESAKTDTYYWQFCTGKD
                     SQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESVRLVYCFAHVRRKFF
                     EAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQQELRPLFIAFYEWM
                     ATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERNIKELVIGRKNWLHS
                     TSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLSAETLDQLLPWNKDV
                     QQHFSRN"
BASE COUNT          584 a          314 c          360 g          482 t
ORIGIN      
        1 aacctcgagc tattttgcca ggaaaaaaag gagtttttta agctgggggg ttaacacaaa
       61 aaatgtgttg aacccctatt tcttgtgcgt ttcttgtggt attctgtaac aaaatcagtt
      121 cgattcaagg tggtgaaaaa ttttggaaac tacagatacg ttgcttcagt tgcttcaaga
      181 agcccataaa accaatcaag cacaacaaca aaccattcag aatcttacaa ctgaaatcca
      241 actattgaat gaaaaggtca attatttaac caacaaatta tttggacgct ctaaagagac
      301 tctctttgag gaaacgaatg ggcaattgaa tctttttagt gatgaagaaa tttctgtaag
      361 tgttccagaa gcagctgcca ccattattcc agtaaaagga catcaacgag ttgtaggaac
      421 gaaagcagac aaaatcaaac acttacctat aacagagaaa gaacatctcc ttcctttgga
      481 agaacaattt tgtgaacatt gcggttcaca gatgaaagat atcggacgga caaaagtacg
      541 agaagaaatt cgtttccatc aggctatgtt ggattgtctc acccattatc aacataccta
      601 ttgttgtaaa agctgcgaaa aagaaggact ttcttctttt aaaaaagcga tcgttcctaa
      661 acctttgatt tctaatagct taggttccaa tagtttagtg gcggaaacga tccggatgaa
      721 atttggtcag aaagttcctg cctatcggca agagaactat tggaaacaaa cacatgggtt
      781 ggatatttcg agagataata tcaccaattg gcatattaaa gcagtgcaaa acgcgttaga
      841 ccctttagga gaacgattaa gagtctatct taatcaagaa gagattctac acggggatga
      901 aacaagttat cgtgtgattg aaagtgccaa aacagatacc tattactggc agttttgtac
      961 aggaaaagac agtcagcatc ccatcgttta ttatcaccac gacgaaagtc gtgctggaga
     1021 tgttccgaaa acttttctca aggagtttac agggtattta cactgtgacg gctatagcgg
     1081 gtataatgcc gtggaaagtg tacgacttgt ctattgtttc gcgcatgttc ggcggaaatt
     1141 tttcgaagca attccaaaag gaaagaaaaa cacggatatt cccgcagctc aagcagtcaa
     1201 acaattggat aaatggtttg tcctagaaaa gaaatggaaa gacttttctc ctgagaagcg
     1261 attaagctgt cggcaacaag aactgcgtcc attatttatt gctttttatg agtggatggc
     1321 aacgatagat cctgttgcaa aatccaagtt ggatgcagcc gttcaatatg cgtgtaaact
     1381 acgaagtggt tttgaaccta tttttgaaga tggtcgttta gaactcacaa ataatcgtgc
     1441 ggagcgaaat atcaaagagc tggtgatagg acggaaaaat tggttgcatt ccacaagtct
     1501 tgaaggagca cgaacttcag gaatcattct gagtgtatat aaaacagcag aacttaacgg
     1561 attgaatcct gtaaagtatc tagagtttct atttgataag ataccaaatc ttcccgtact
     1621 ttcagcagaa actttagatc aactgttgcc ttggaacaag gatgtacaac aacatttttc
     1681 tcgtaactaa aaacgccaaa cattcccgat tctattctat aggtcgggtt atttgacgta
//
LOCUS       DAMEEU010000165         1706 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.171, whole genome shotgun sequence.
ACCESSION   DAMEEU010000165 DAMEEU010000000
VERSION     DAMEEU010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1706
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.171"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            49..471
                     /locus_tag="PB779_002885"
     CDS             49..471
                     /locus_tag="PB779_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740358.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            481..684
                     /locus_tag="PB779_002886"
     CDS             481..684
                     /locus_tag="PB779_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740359.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            895..1479
                     /locus_tag="PB779_002887"
     CDS             895..1479
                     /locus_tag="PB779_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HDE0740360.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
BASE COUNT          601 a          242 c          310 g          553 t
ORIGIN      
        1 atttattaag aaaacgtttt cttatttttg atttcgaggt gatagacaat gaaaaataag
       61 tttattttat ctttaggtat tttaactatt ggaattagtg taactggaac tacaattcct
      121 acatttgctg atagtacaaa tgaaccaact actgtagtag ataataacca agaattaact
      181 cctttagata ggaacggaat agccattggt aacccaacta acgacttaac tgttactgaa
      241 aattatttaa tagtttctcc attacttgct cgagcagctt ctaaaacgat acgagtgaca
      301 ggaacgatga tttttgataa agttggttgg ccttctagac ctcctcaatc acggaattgg
      361 aaagaaaaaa gaaatggtta ttggtactat ggaaaattgt atttacaaag ttataaatca
      421 gctggaaaca attggattgc gacttattca ggaaccttaa ctagaaagta gggatttttt
      481 atgccagaat ttgtgaacac accaaatttt tatcaagata gcgatattct aagtaaaatt
      541 aatttaccga aagaagaatc agctttacaa gttcagcgaa ctttacagga gacacaaaaa
      601 attcaaaaat caatttctaa tctagaagat tctgaagaaa aaagaaaaaa aagagaccaa
      661 aaaacatatc aaaaagaaaa ataatgattt taaaaaaaga gtgtctagtc gacattcttt
      721 ttttctaatt gaaagtgttc ataaaatcac ccatttctgg acactttctt tttttgcttt
      781 atttttcaaa aaaacaattc atttcatgtt cataaaccca taacaatatc tatgttcagt
      841 taaactatat ggataaagtt atgttacaat aaaattaatg aaggagtgat ttttttgaaa
      901 ataggatacg cccgggtatc tactggttta caaaatttgg atttacaaga agacagccta
      961 aataaatttg gttgtgaaaa aatttttact gatcatatga gtggggcaaa aagtaatcga
     1021 ccaggattag aaatggccat tgattttgtt cgctctggcg atacacttgt cgtttggcgc
     1081 ttagatcgtt taggtagaaa tatggaagat ttgatttcaa tcgtcaatcg actgaatgag
     1141 cgtggtgtga gttttcatag tattcaagaa aatattacga tggacaaatc aagttctaca
     1201 ggacagctca tgtttcattt gtttgcggca tttgcagaat ttgagcgtaa tttgatcctg
     1261 gaacgatccg cagcaggacg agcagctgct cgtgcaagag gacggtttgg tggtcgtcct
     1321 gaaaaattgt ctgaacaaga tttggaatta ctgaagactt tagtggatag cggtacacct
     1381 attaagacta ttgcggaacg gtggaacgtc tcaagaacca ccatttatcg ttatttggca
     1441 aaaatggagg agaaaaatgg aaagacaaat tctcattagt ttttgtcatt taatgctgaa
     1501 aatttttgcc atttatctag aaaagtgaca atagtatgag aattttttgt aagtgtctac
     1561 tgataactta ttctcaaatg ttgtaaggat tttattcatt tgttaatatt aaagaacgga
     1621 actccaaaaa agtccgtact ctaatttgca gtctctcact cttttagagt gagagttttt
     1681 attagatttt caaattaatt agtaaa
//
LOCUS       DAMEEU010000166         1607 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.173, whole genome shotgun sequence.
ACCESSION   DAMEEU010000166 DAMEEU010000000
VERSION     DAMEEU010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1607)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1607)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1607
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.173"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..626)
                     /locus_tag="PB779_002888"
     CDS             complement(<1..626)
                     /locus_tag="PB779_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740361.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGRLDDSP
                     SHCEHCGSIRIIRNGSYTTRTQILKVKEKLTILELKRTRFLCYDCGQTFSAKTDLVDE
                     HHQLTKELKQAILIELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMKSVSGSMSFICVDGTTHQLFTILEDRRLYKLTQYFLRFPR"
     gene            914..1567
                     /locus_tag="PB779_002889"
     CDS             914..1567
                     /locus_tag="PB779_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HDE0740362.1"
                     /translation="MKILTVEDDNMIREGISEYLSEFGYTVIQAKDGREALSKFNSDI
                     NLVILDIQIPFINGLEVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFS
                     LPVLKARIDSLIKKNYGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLD
                     NNGQVLTRMQIIDYVWKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          578 a          225 c          299 g          505 t
ORIGIN      
        1 tttctaggaa agcgcaggaa gtattgagtt agtttgtaaa gtctgcgatc ttcaaggatc
       61 gtaaatagct gatgggttgt cccatcaaca caaataaaac tcatggaacc agaaacagac
      121 ttcattgatt tgaactcatc catacacaac accgtcggaa ggaagttcat acgtggctgg
      181 taatgcttcg ttgcttcacg caagatccgt gtcaccgtcc catccgagac gaagtacttc
      241 ttagcgatta gtttacgtga ttgattttcg tacagttcta tgagaatcgc ctgcttcagt
      301 tcctttgtta gttgatgatg ttcatcaact aagtccgttt tcgcagaaaa ggtctgccca
      361 caatcatagc atagaaaacg ggtacgtttt aattctaaaa tagtcaactt ttctttgact
      421 ttcaatatct gagtacgtgt cgtataggaa ccgttgcgga taatacgaat cgatccacag
      481 tgttcacaat gggaaggtga gtcatccaat ctccctttaa taaactgcgc ttgaacgcct
      541 ttatattctt tttcaatcag ccattcttca tcaaaaaata aatgtttatc tgttaatccg
      601 agtaattttc tagtatgatt atccatagag cgactccttt ggtagggtga tgttttggtc
      661 gactaaattt taccaaaagt gagtctcttt ttgagttgaa acgaagaaaa agtgttagta
      721 gaaaatcgcc ttcgattttc caacaacaca aaatattata gaacccttta ttctaaagga
      781 tttcaaggtg tctgtttgca tttattagaa aaaagaaaaa gtattggcaa cagaaggtgt
      841 caccaacact agatattata gagccataat atgctgtata atatctagtg tataggctta
      901 agtggaggta tatatgaaaa tattaactgt tgaagatgat aatatgataa gagagggaat
      961 aagtgaatat ctttcagaat ttggatatac tgttattcaa gctaaagatg gaagagaagc
     1021 cttgtcaaaa tttaatagcg atataaattt ggttatctta gacattcaga taccttttat
     1081 aaatggttta gaagtgttga aagaaattag aaagaaaagc aatttaccaa ttctaatctt
     1141 gactgcattt agtgatgaag aatataaaat tgatgcattt actaatttag tagacggata
     1201 tgtagaaaag ccattttcat tgccggtctt aaaagctaga atagattctt taattaagaa
     1261 gaattatgga catttagaga agtttgaata taaggatcta tcggttaatt ttaatagcta
     1321 tacagctaaa ataaatggtg aagaaataga tgtaaatgca aaagaactag aagtattaaa
     1381 atgtttattg gataataatg gacaagtgtt aacaagaatg caaattattg attatgtatg
     1441 gaaagatagc gaagaaactc cttatgatcg agtaatagat gtatatataa aagaacttag
     1501 aaaaaaatta caattagact gtataactac tataagaaat gtaggatata aattggagag
     1561 aaaatgaaaa aattaaagat atttccaaaa atgttcatac aaatatt
//
LOCUS       DAMEEU010000167         1519 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.174, whole genome shotgun sequence.
ACCESSION   DAMEEU010000167 DAMEEU010000000
VERSION     DAMEEU010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1519
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.174"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..330
                     /locus_tag="PB779_002890"
     CDS             <1..330
                     /locus_tag="PB779_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HDE0740363.1"
                     /translation="VVSARRNPYFNMVKRIENEVTIVNKSRYTSRQQTPEVFEMNASM
                     YSFKPEFLKKSNYIFDGQCGIIKMRDYLILDIDSEEDFKWLEFLFPKFLEDSSELQDI
                     YNYLYRR"
     gene            335..1282
                     /locus_tag="PB779_002891"
     CDS             335..1282
                     /locus_tag="PB779_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HDE0740364.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT          507 a          211 c          311 g          490 t
ORIGIN      
        1 gttgtttctg caagacgtaa tccctatttt aatatggtaa aaagaattga aaatgaagtt
       61 actatagtta ataaatcaag atacacatct aggcaacaga cacctgaagt ttttgaaatg
      121 aatgcctcaa tgtattcttt taaacctgaa tttctaaaaa aaagtaatta tatttttgat
      181 gggcaatgtg ggataataaa aatgagagat tatctaattt tagatattga tagtgaagaa
      241 gattttaaat ggttagaatt tttgtttcct aaatttttag aagattcttc ggagcttcaa
      301 gatatctata attatttata tcggaggtaa aaggatgagc tgttatctta tcaccggtgg
      361 ggctggcttc attggttcta ccttagccaa tcatttagga gaagaacatg tggtaatcgt
      421 cgtcgatgac ttatcaatgg gaaaagtaga aaatcttgat atgacgaaaa atatcacttt
      481 tattgaggga gatgtcgctg agaaatcctt gatggaagag atcatgaaag ctaataaatt
      541 tgattatatc tttcatttag cagcagttgc tagtgtggca gattcagttg cccgaccagt
      601 agaaacacat cgtgtgaatt ttgaaagtgt attaatgatt ttagaattga tccgcaagta
      661 tcaacctgat ttaaaacgga tcgtgtttag ttcttcagcg gctgtttatg gggatgaacc
      721 gactttacca aaaaaagaag agtccgtgat tcgcccattg acgccttatg cggttgataa
      781 attcgctgca gaacaatatg tgctagatta ttgtcattta tatgatgtac ccggtagcgc
      841 agttcgtttt ttcaatgtct atggtccaaa tcaaaatccg aattctccat acagtggtgt
      901 gatttctatt ctcgtagatc gctataagaa acaaatcgta ggagaagcaa cttcatttac
      961 attatttggt gatggaagcc agtctagaga ctttgtttat atagatgatg taatccaagc
     1021 attactttta gttgcgaatg aggaagctgc actggggaaa caattcaatg ttggaacggg
     1081 taaagcaacc acacttttgg aattgattca tgcaatcaat gaaattctcg gtgtagaatt
     1141 gacacttgaa tacaaagaag agcgttcggg tgatatccat gactctctag cagatattac
     1201 taagatccag tcaattggct atcaaccgaa atatggtatt ttaagtggaa tgactaatta
     1261 tttgaaaact gaaatcaatt aaaacatact aagataagat tagagggtaa attcaggctc
     1321 tttgtcaata aggactgatg agttttgtaa aatcaaatct gggatagaag ggctctttgt
     1381 caaatgatgt tggtaaagag aaatcttaga ataatttgga cagaacagaa agaagaaaac
     1441 ctctttctgt tctgtttatt tggttaaaaa tgttttgcca tgacgaatca taattcgtag
     1501 tttgaaattg taaaagttg
//
LOCUS       DAMEEU010000168         1476 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.175, whole genome shotgun sequence.
ACCESSION   DAMEEU010000168 DAMEEU010000000
VERSION     DAMEEU010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1476
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.175"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            861..1073
                     /locus_tag="PB779_002892"
     CDS             861..1073
                     /locus_tag="PB779_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740365.1"
                     /translation="MKNRLEELRKQRGIKQEDLASALEVSRQTIGSLENGRYNPSIIL
                     AFKIARYFQMSIEEIFIYEEESEDEK"
     gene            1063..1458
                     /locus_tag="PB779_002893"
     CDS             1063..1458
                     /locus_tag="PB779_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740366.1"
                     /translation="MKNKGQIWYIGYIVSLFLIVTILVTDFPKMVDIGLAILFSAVFG
                     VSHVQILHDKMIKNDADYKINVMDERNIIIKEKAGNITNMFNTILLGVATVIFICLDY
                     IIPAIIVGSIIAIQPIILIIISSVLEKKM"
BASE COUNT          515 a          217 c          250 g          494 t
ORIGIN      
        1 ggtgtaaaac agttataaga aatgagtact ctagtatttg tgttacccga ataattactt
       61 gattatattg gtttcccata taattgaagg ctgtcctaat ttttacctac tatatgatca
      121 taattgatta actcttatat atttccgaaa attatcttga agatttctat tggtatggag
      181 aatatccatt tcattgccaa taaggatata aattctcaaa ataacaatcg atgtctgtat
      241 taaacaagcc tagaatggta aatctgattc gccaaaacca ttggattgta tcgatttgct
      301 ttacgcgaac gccacctacc cattttataa aaataaaatg ggcaaaagat ctttcttttt
      361 gtcatacaaa aagaagaaaa aaaagagacg attttcttct tccaaaatcg tccctctttt
      421 ttctaaaacc atggatgaac gaacaaaaaa tctctcgtat tttgtttgtt catccactaa
      481 aaatatgcga acagtatggt ttcattcaat cctgttctta caagtcaaaa gcatcgaatc
      541 gtccttggac gattcaacaa aaaaagtagt cgtttttgga tgactactaa gttctaaaca
      601 ttcattaccc aaaatcaatt tggtctaaca tcgtttctcg actggcttga tctaatcggc
      661 tcttgacagg gctttttctt ttctgttgat agcagataag aggaaataag aataagtgtg
      721 ttcatgtgtc ataaaaacag taactaaaac attaaaatca aaatttatat ggaaagcttc
      781 cttgacattt tgtgctcgca ggagtattat aaaagcacga aaggaaagta aactttccat
      841 tttttagaaa ggagcatgtt gtgaaaaatc gtttggaaga attacgaaaa caaagaggaa
      901 ttaaacaaga agatttagct tctgctcttg aagtatctcg tcaaacaata ggttctttag
      961 aaaatggacg ttataatccc tctattatat tggcatttaa aattgcaagg tactttcaaa
     1021 tgagcattga agaaattttt atctatgagg aggaaagtga agatgaaaaa taagggtcag
     1081 atttggtata tcggttatat tgtttcgttg tttttgattg tgacaatttt ggttacagat
     1141 tttcctaaaa tggtagatat tggacttgct attttattca gtgccgtttt tggcgtttct
     1201 catgttcaaa ttttgcatga taaaatgatt aaaaatgatg cagactacaa aatcaatgtt
     1261 atggacgaac ggaatatcat aatcaaagaa aaagcgggaa atataacaaa tatgtttaac
     1321 acaatactgt taggggtggc aacagttata tttatttgtt tagactacat cattccagct
     1381 attattgtcg gaagtatcat tgcaatccag ccgattattt taatcattat cagtagtgtg
     1441 cttgagaaaa aaatgtagaa ataaaggttc atacaa
//
LOCUS       DAMEEU010000169         1442 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.176, whole genome shotgun sequence.
ACCESSION   DAMEEU010000169 DAMEEU010000000
VERSION     DAMEEU010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1442
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.176"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(91..175)
                     /locus_tag="PB779_002894"
     tRNA            complement(91..175)
                     /locus_tag="PB779_002894"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(139..141),aa:Leu,seq:caa)
     gene            complement(193..264)
                     /locus_tag="PB779_002895"
     tRNA            complement(193..264)
                     /locus_tag="PB779_002895"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(230..232),aa:Gln,seq:ttg)
     gene            complement(274..346)
                     /locus_tag="PB779_002896"
     tRNA            complement(274..346)
                     /locus_tag="PB779_002896"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(311..313),aa:His,seq:gtg)
     gene            complement(408..492)
                     /locus_tag="PB779_002897"
     tRNA            complement(408..492)
                     /locus_tag="PB779_002897"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(456..458),aa:Leu,seq:caa)
     gene            complement(513..583)
                     /locus_tag="PB779_002898"
     tRNA            complement(513..583)
                     /locus_tag="PB779_002898"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(549..551),aa:Cys,seq:gca)
     gene            complement(629..700)
                     /locus_tag="PB779_002899"
     tRNA            complement(629..700)
                     /locus_tag="PB779_002899"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(666..668),aa:Gln,seq:ttg)
     gene            complement(712..784)
                     /locus_tag="PB779_002900"
     tRNA            complement(712..784)
                     /locus_tag="PB779_002900"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(749..751),aa:His,seq:gtg)
     gene            complement(787..860)
                     /locus_tag="PB779_002901"
     tRNA            complement(787..860)
                     /locus_tag="PB779_002901"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(826..828),aa:Trp,seq:cca)
     gene            complement(867..947)
                     /locus_tag="PB779_002902"
     tRNA            complement(867..947)
                     /locus_tag="PB779_002902"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(911..913),aa:Tyr,seq:gta)
     gene            complement(949..1024)
                     /locus_tag="PB779_002903"
     tRNA            complement(949..1024)
                     /locus_tag="PB779_002903"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(989..991),aa:Phe,seq:gaa)
     gene            complement(1060..1132)
                     /locus_tag="PB779_002904"
     tRNA            complement(1060..1132)
                     /locus_tag="PB779_002904"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1097..1099),aa:Asp,seq:gtc)
     gene            complement(1142..1214)
                     /locus_tag="PB779_002905"
     tRNA            complement(1142..1214)
                     /locus_tag="PB779_002905"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1179..1181),aa:Val,seq:tac)
     gene            complement(1230..1301)
                     /locus_tag="PB779_002906"
     tRNA            complement(1230..1301)
                     /locus_tag="PB779_002906"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1266..1268),aa:Glu,seq:ttc)
     gene            complement(1316..1405)
                     /locus_tag="PB779_002907"
     tRNA            complement(1316..1405)
                     /locus_tag="PB779_002907"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1369..1371),aa:Ser,seq:gga)
BASE COUNT          417 a          369 c          327 g          329 t
ORIGIN      
        1 atacttgtat cgaattgatt tggaggtaat tacataaaaa caaaaaaaat atagcaactc
       61 tctataagaa agttgctata ttgataatta taccggcggc cggggtcgaa ccggcacgtc
      121 ctcaacggac actggatttt gagtccagcg cgtctgccaa ttccgccacg ccggcaaatt
      181 taaaaataat aactggggta gctggattcg aaccaacgca tgagggagtc aaagtccctt
      241 gccttaccgc ttggctatac cccaagaata aagggcgaat gatgggaatc gaacccacga
      301 atgccggagc cacaatccgg tgcgttaacc acttcgccac attcgccatc ataaaagatg
      361 ttatttaatt tctcaataaa aaactaagat gaagacatct tagtcaatac cggcggccgg
      421 ggtcgaaccg gcacgccctc aacgggcact ggattttgag tccagcgcgt ctgccaattc
      481 cgccacgccg gcaagttgat ttattagtac taaggcggta accggatttg aaccggtgat
      541 gaaggttttg cagacctctg ccttaccact tggctatacc gccattatac tattatcaat
      601 ctataaaata aagaataaat tatagaaact ggggtagctg gattcgaacc aacgcatgag
      661 ggagtcaaag tcccttgcct taccgcttgg ctatacccca agaataaaaa gggcgaatga
      721 tgggaatcga acccacgaat gccggagcca caatccggtg cgttaaccac ttcgccacat
      781 tcgccatggc aggggcagca ggaattgaac ccacactaac ggttttggag accgctgttc
      841 tacctttaaa ctatgcccct ataaaatgga ggagagtgga ttcgaaccac tgaaccctaa
      901 ggaacggatt tacagtccgt cgcgtttagc cacttcgcta ctcctccatg gtggcgcggg
      961 acagaatcga actgccgaca cacggagctt caatccgttg ctctaccaac tgagctaccg
     1021 cgccatattt taaaattatt aattgaataa caagaacgac ggttccgacg ggaatcgaac
     1081 ccgcgatctc ctgcgtgaca ggcaggcatg ttaaccccta caccacggaa ccagttcatt
     1141 atggaggtta acgggatcga accgctgacc ctctgcttgt aaggcagatg ctctcccagc
     1201 tgagctaaac ctccaacatt caattaaaat gacccgtacg ggattcgaac ccgtgttacc
     1261 gccgtgaaag ggcggtgtct taaccgcttg accaacgggc caggtaaatt tgctacggag
     1321 agtaagggat tcgaaccctt gagacagttt ggcaccatct acatgatttc caatcatgct
     1381 ccttcggcct ctcggacaac tctccagagt gaaagaagct caatactctt tctcaaaatg
     1441 ag
//
LOCUS       DAMEEU010000170         1415 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.178, whole genome shotgun sequence.
ACCESSION   DAMEEU010000170 DAMEEU010000000
VERSION     DAMEEU010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.178"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            90..1382
                     /locus_tag="PB779_002908"
     CDS             90..1382
                     /locus_tag="PB779_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDE0740367.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          460 a          288 c          256 g          411 t
ORIGIN      
        1 atctttttta ttttccaaaa catatagaaa agacaccttg aaatccttta gaattaattt
       61 ggcgaaccaa cccaaaagga ggaatcaaga tgtcttacac tcaccttatc aaagaaacat
      121 tagatattct agacttatca gttactttta acgaaaattg tctcacaaaa gaaaaataca
      181 aagggcaaat ctgtcatatt tatcgtggaa acttgattta tacagcccaa gaatgcatcc
      241 actgtaaaca ccagattgct tcagatattg tgcgttgggg tacaacaacc gtccggttgt
      301 taatgaacga tgtttctgaa taccgtacct acctcgaatt gaaaaagcaa cgcttcaaat
      361 gcaaagcttg tcagcggacc tttgtcgcag atacttctgt tgcgaaaaaa cattgtttca
      421 tcagtgagaa agtccgctgg tctgtcgtga ctcgtctgaa aaaaaatacc tcaatgacag
      481 agatcgccgc tcagaaaaat ctatcggtct cttctgttta ccgtattatg aagcgatttt
      541 atcgtccgtt gaatcctttt cggacaccgt tacctaaggt actttgtttt gatgaattca
      601 aatcagttcg gggtgtttca ggtgctatga gtttcatcat gatggatgga caaacacagc
      661 gcttattgga cattgtcgag aaccgacaac tgcctttttt aaaacgttat tttagtcatt
      721 tttcacgaga aattcgtgaa gcggtcgaat ggatcgtgat tgatatgtac gctccttatg
      781 tatcgctcgt taaaaagctg tttccaaaag cacagctgat tattgaccgg tttcacatcg
      841 tccaacatat tggtcgtacc tttcgcaatc atcgaatcaa agaaacgaac caactattaa
      901 aaagcaaaga acaaaaacac tatcaattag gtaagcaatt aaaaagatac tggaaacttc
      961 ttcaaaaaga tgaacgcaag cttgattata ctcgacgcct ttggcgacct ggcttcaaag
     1021 ctcatttaac agagaccgat attgtggatc gcttactgaa agggagccct gctttgcgtg
     1081 taggctatca gttatatcaa gactttcttt acgctgtaaa ggaacgagac tacgtatcgt
     1141 ttgaagaact acttaccaat aatatcatgc ttcccgaagg ctatcagacg accttgagaa
     1201 cgttccagaa atttctgcca caaatcaaaa atgctttaca acaaagttat tcaaatggcc
     1261 cacttgaatg tctgaacaac catatcaaag tgttaaaacg aaatgcatat ggctttcgta
     1321 gcttttataa tttcaaattg cgcatcatga ttcgtcatgg caacgcattg attttcaact
     1381 aaaaaagatc aagaggaact gatccacttg atctc
//
LOCUS       DAMEEU010000171         1415 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.179, whole genome shotgun sequence.
ACCESSION   DAMEEU010000171 DAMEEU010000000
VERSION     DAMEEU010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.179"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..376
                     /locus_tag="PB779_002909"
     CDS             <1..376
                     /locus_tag="PB779_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS6-like element IS1216 family transposase"
                     /protein_id="HDE0740368.1"
                     /translation="WLRKKRDTQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLK
                     EYGFYQGTEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEAIRGLYKKTR
                     KEGTLFGFSVCTEIKVLLGIPA"
     gene            471..1022
                     /locus_tag="PB779_002910"
     CDS             471..1022
                     /locus_tag="PB779_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HDE0740369.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
BASE COUNT          525 a          220 c          273 g          397 t
ORIGIN      
        1 ttggttacgt aaaaaacggg acacacaagc agcctatgct tttcttaagc ggttagtgaa
       61 gcagtttgat gaaccgaagg ttgtagtcac agataaagcc ccctctatta caagtgcctt
      121 taagaaacta aaagaatacg gcttttatca agggacagaa catcgtacca ttaaatacct
      181 gaataatttg attgaacaag accatcgtcc agtaaagaga cgcaataaat tctatcgaag
      241 tttacgcact gcctctacca cgattaaagg catggaagcc attcgaggat tatataagaa
      301 aacccggaaa gaaggcactc tcttcgggtt ttcggtctgt actgaaatca aggtattatt
      361 gggaatccca gcttaaatca tagataccgt aagggatttt attctttatt taaaactttg
      421 caacagaacc gaagagcgag caagacagga acgagagaac aaacatactc atgaaaagac
      481 tagaggcttc gacctcgaac tttaataata agttagatgt ttttgaagaa aagactaagc
      541 atgcaagatt aaactttgaa acaactgcaa agcactatat taaacgactt gatgaagata
      601 atttgaaatt agattttcaa caagctattc aagatgaatt aagcgatact aaagacgaaa
      661 tacgtgaagt gacgaaacaa gcgagagaag aaacaaaaga gtataaagaa atcttagaaa
      721 gtaaaataaa agaccataac aaagtggttg ataaatcgaa tacagcgcta aaagtgatga
      781 caaaaggcgt tacaaatata ttttttgtgc taattatttt tgtacttgta atgcttgtga
      841 caggtccgat aggtcatttc tttggtattg aacatttata tagctttatt aatggtttta
      901 ttgatgacca cgaaagtgca tggcgatatt tgatgttgat actttatgca gtaccctatg
      961 tattcttcgc tatcattctg tggctcatag cattgttttt tagagtattt aatgaccttt
     1021 aggtagattt atatataaaa agggctaaat acgcaaaata cccccttaaa atgcaaaata
     1081 aatgcaaata agggggtaac tccttatgaa aaaacaacta atagtattat aacacgtttt
     1141 tatgccgaga aaacttattg gttggaatgg gctatgtgtt agctaacttg ttagcgagtt
     1201 ggttggactt gaattgggat taatcccaag aaagtaccaa ctcaacaaca cataaagccc
     1261 tgtaggttcc gaccaataag gaaattggaa taaagcaacg aaaggagttg agtaaaatga
     1321 gtgagaaaac gaagaaaatc attcgagtat cattagcttt ttcacaagta gtagtgcaat
     1381 cattgatagt ttattatact taccagcaat ataaa
//
LOCUS       DAMEEU010000172         1385 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.180, whole genome shotgun sequence.
ACCESSION   DAMEEU010000172 DAMEEU010000000
VERSION     DAMEEU010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1385
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.180"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..1307
                     /locus_tag="PB779_002911"
                     /note="aph(2'')-Ia"
     CDS             <1..1307
                     /locus_tag="PB779_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase APH(2'')-Ia"
                     /protein_id="HDE0740370.1"
                     /translation="LKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYP
                     KTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRA
                     YQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSI
                     EIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYS
                     YISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECT
                     IDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNH
                     LLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKA
                     KEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          595 a          103 c          233 g          454 t
ORIGIN      
        1 cattaaaaaa acattataca gagccttggg aagatgaagt ttttagagta attattgaat
       61 ataacaatgt tcctattgga tatggacaaa tatataaaat gtatgatgag ttatatactg
      121 attatcatta tccaaaaact gatgagatag tctatggtat ggatcaattt ataggagagc
      181 caaattattg gagtaaagga attggtacaa gatatattaa attgattttt gaatttttga
      241 aaaaagaaag aaatgctaat gcagttattt tagaccctca taaaaataat ccaagagcaa
      301 taagggcata ccaaaaatct ggttttagaa ttattgaaga tttgccagaa catgaattac
      361 acgagggcaa aaaagaagat tgttatttaa tggaatatag atatgatgat aatgccacaa
      421 atgttaaggc aatgaaatat ttaattgagc attactttga taatttcaaa gtagatagta
      481 ttgaaataat cggtagtggt tatgatagtg tggcatattt agttaataat gaatacattt
      541 ttaaaacaaa atttagtact aataagaaaa aaggttatgc aaaagaaaaa gcaatatata
      601 attttttaaa tacaaattta gaaactaatg taaaaattcc taatattgaa tattcgtata
      661 ttagtgatga attatctata ctaggttata aagaaattaa aggaactttt ttaacaccag
      721 aaatttattc tactatgtca gaagaagaac aaaatttgtt aaaacgagat attgccagtt
      781 ttttaagaca aatgcacggt ttagattata cagatattag tgaatgtact attgataata
      841 aacaaaatgt attagaagag tatatattgt tgcgtgaaac tatttataat gatttaactg
      901 atatagaaaa agattatata gaaagtttta tggaaagact aaatgcaaca acagtttttg
      961 agggtaaaaa gtgtttatgc cataatgatt ttagttgtaa tcatctattg ttagatggca
     1021 ataatagatt aactggaata attgattttg gagattctgg aattatagat gaatattgtg
     1081 attttatata cttacttgaa gatagtgaag aagaaatagg aacaaatttt ggagaagata
     1141 tattaagaat gtatggaaat atagatattg agaaagcaaa agaatatcaa gatatagttg
     1201 aagaatatta tcctattgaa actattgttt atggaattaa aaatattaaa caggaattta
     1261 tcgaaaatgg tagaaaagaa atttataaaa ggacttataa agattgatta tataatatat
     1321 gaaaagctat tataaaagac attagtatta aatagtttaa aaaaatgaaa aataataaag
     1381 gaagt
//
LOCUS       DAMEEU010000173         1368 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.181, whole genome shotgun sequence.
ACCESSION   DAMEEU010000173 DAMEEU010000000
VERSION     DAMEEU010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.181"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            82..>1368
                     /locus_tag="PB779_002912"
     CDS             82..>1368
                     /locus_tag="PB779_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HDE0740371.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQLIN"
BASE COUNT          467 a          263 c          257 g          381 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taatcaat
//
LOCUS       DAMEEU010000174         1313 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.182, whole genome shotgun sequence.
ACCESSION   DAMEEU010000174 DAMEEU010000000
VERSION     DAMEEU010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.182"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            200..742
                     /locus_tag="PB779_002913"
     CDS             200..742
                     /locus_tag="PB779_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740372.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..1272
                     /locus_tag="PB779_002914"
     CDS             898..1272
                     /locus_tag="PB779_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HDE0740373.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMPDVEWQHFF"
BASE COUNT          532 a          148 c          256 g          377 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tctggatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccagatgt ggaatggcaa
     1261 cacttttttt gacaaaaatt ataaggtgtt gtgaatgctg cggtgttatg gct
//
LOCUS       DAMEEU010000175         1225 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.183, whole genome shotgun sequence.
ACCESSION   DAMEEU010000175 DAMEEU010000000
VERSION     DAMEEU010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1225)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1225)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1225
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.183"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            86..>1225
                     /locus_tag="PB779_002915"
     CDS             86..>1225
                     /locus_tag="PB779_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086557923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDE0740374.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQI"
BASE COUNT          379 a          236 c          240 g          370 t
ORIGIN      
        1 atcttttttg tataaaaaaa tatagaaaag acaccctgaa atcctttaga attaatttgg
       61 ctaccaattc ataggaggat tcaagatgtc tcatactcag cttatcaaag ataccctaaa
      121 tattctagac ctaaatatct atttcgagga aaattgttta actaaagaaa aatacaaagg
      181 gcaaatttgc ttgatttaca aaggaactct tctgtacaag ccagaagagt gttcccattg
      241 tctttgtgtc gtcccctcta ggatcattcg ttgggggacg acaaccgttc ggttgttact
      301 gaatgatgtg tctgagtatc gcacttatct ggagctgaag aaacaacgat ttaaatgtaa
      361 gtcttgccaa agaacattcg tagcggatac ctctgttgct gaaaaacact gtttcattag
      421 tcaaaaagtt cgttggtctg tcattgctcg cttaaaagag aatacttcca tgacggaaat
      481 cgctcgtcag aaaaatattt ccacttcttc ggtctatcgt gtcatgaagc gattctaccg
      541 cccattgaat cctttcaaac agactttgcc aaaggtctta tgctttgatg aattcaaatc
      601 ggttcgaagt gttgccagtg caatgagttt tatcatgatg gacggacaaa gccatgcatt
      661 attggatatt gtcgaaaatc gacgcttgcc ttatttagaa cgctattttt ctcggttttc
      721 attagcgact cgtgaagccg ttcaattgat tgttattgat atgtatgcgc cttatgtttc
      781 gttggtgaaa aagcttttcc cgaatgctca gttgatcatc gatcgtttcc acatcgtcca
      841 acatattggc agaactttct tgaatcatcg agtgaaagaa accacggtac gacttaaagg
      901 aaattcccac tctcaacgag ggttagggaa aaaattgaag cgctattgga aactcctaca
      961 aaaagaagaa gcaaagttaa actatgaaaa acgggtttgg cgtgccagtt ttaaagatta
     1021 tttgactgaa agtgagattg ccgatcgact gttagctgct tgtcccaact tacgccaagg
     1081 ctatcagtta taccaagaca ttctttatgc ggtaaagaaa agagatcagt cactatttga
     1141 ggattgttta actagagaca ttagcggtct gccagaaacc tatacaacca ctttacgaac
     1201 gtttaaaaag tttctgccac agatc
//
LOCUS       DAMEEU010000176         1156 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.184, whole genome shotgun sequence.
ACCESSION   DAMEEU010000176 DAMEEU010000000
VERSION     DAMEEU010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1156)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1156)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1156
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.184"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..1061)
                     /locus_tag="PB779_002916"
     CDS             complement(<1..1061)
                     /locus_tag="PB779_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016372324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740375.1"
                     /translation="MKANILEAIFFDEHHNWDNFVEKYGRKIRLVVKREVNKFRYCGD
                     IQKGYRLFVCEGCHQTKFVPLKCRGKFCPTCATGESQRWSAVVANDMFKVTHRHVIFT
                     IDEGLREIFMMENYRDSLLKGLMDEAAKIILAYFEKRKVKAGIVATIHTFGSKLEFNP
                     HVHMVVTMGGLTRDGSWEEYDYLPFSMLRKYWKNAVLKLIRRTLGEWDKQRVQSRLQA
                     AYKNNGEGFYVNAPKRSRTNLKSLLQYISRYMKRGPIALSRILMYDGDTVMFNYMDKR
                     TNTKETMTMSIDEFIAALIRHIQNKNFKTIRRYGIYSRRIKTLMKKVMKEYQKRVKKL
                     FINLNEALRPKSWEERITE"
BASE COUNT          304 a          257 c          183 g          412 t
ORIGIN      
        1 tcttcggtta ttctttcttc ccaggatttt ggtcttaagg cctcattcag attgataaac
       61 agctttttta ctcgtttctg atactccttc atgacctttt tcattaatgt tttgattcta
      121 cgactataga ttccatagcg acgaatcgtt ttgaaattct tattttgaat atggcgaatc
      181 agtgcagcta tgaattcgtc tatactcatg gtcatcgtct ctttagtatt cgttcgtttg
      241 tccatgtagt tgaacatgac agtgtcgcca tcatacatta agattcggct taatgcgatc
      301 gggccacgct tcatataacg actgatgtat tggagtagtg actttagatt tgtcctgctc
      361 cttttaggag catttacgta aaacccttct ccattgttct tgtacgcagc ttgtaatctt
      421 gattgaactc tttgcttgtc ccactcacct aacgttcgtc taattagttt caatacagca
      481 tttttccagt attttcttaa catagaaaaa ggtaaataat cgtattcttc ccaacttcca
      541 tctcttgtta agccacccat agtaacaacc atatgaacat gcggattaaa ttctagtttt
      601 gatccaaagg tgtggattgt agctactata cctgccttca cctttctttt ctcaaaatag
      661 gcaagaataa tttttgcggc ttcatccatt agtcctttca gtaaggaatc tcgatagttt
      721 tccatcataa agatttcccg taacccctca tcgatcgtaa agattacgtg ccgatgtgtc
      781 actttaaaca tatcattcgc cacaaccgct gaccaccttt ggctttcacc tgttgcacac
      841 gttggacaga actttccacg acatttcaag ggaacaaact ttgtttgatg acatccctcg
      901 cagacaaaca gtcggtatcc tttttgaata tctccacaat atctaaactt gtttacttcc
      961 cgtttgacga ctagccgaat ctttcgcccg tatttctcaa caaagttatc ccaattatgg
     1021 tgttcgtcaa aaaagattgc ttcgagaata ttcgctttca tagtaatatt ttacttgttc
     1081 aaaaacaaaa tgaaaagggc taaaagactg gtagtgcagc ctttttagcc cttaactttt
     1141 tatactttct ttactg
//
LOCUS       DAMEEU010000177         1059 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.185, whole genome shotgun sequence.
ACCESSION   DAMEEU010000177 DAMEEU010000000
VERSION     DAMEEU010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1059)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1059)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1059
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.185"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(37..993)
                     /locus_tag="PB779_002917"
     CDS             complement(37..993)
                     /locus_tag="PB779_002917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740376.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          379 t
ORIGIN      
        1 ttagaaaaag cagtcggact ttctaaaaga agttcactat tcgatcctgt cgatgatttc
       61 ttcaggaaaa tcgtctattt gcttgtcaat tttgctgtct ttgtatttct cttcttggat
      121 agtcaacaaa atctttgtaa gattccccca gtctactgct cttggcggat cgagccaaac
      181 cactacttga gatgcacttt cttcatatag attattccta ttcgtgatta taacatccgg
      241 gaactcaggc tttcctgcct ctatcacttc cgtgttcaga ttaatgtaca agcttaaatt
      301 tttcttgata aattgattat aggcagcacc ataagaaaaa tcgatgatga tctttactgg
      361 ttcagaaatc agttgaatgg gtatgtgatt gatcaataat aataaataac tgaaaaaaag
      421 aaaaaattta tcttgaagca actctttgcg ttttgacgtt agatcattta tatactctat
      481 caaatagcaa taaaatgctg gatagttttc tctaaaaaaa gaaacatcaa gtggaaattc
      541 atcagcttta ttaatagtgt aatgcaaaag tttaaaatgt attttggtta actctcttcg
      601 gatcaattgg ctcgtctctt ctcgcaacag attaaactga ttttcaaaac tttcaatgaa
      661 tcgttcattc aaccattcga ttgtttcatc ttcatttttt ctcaagtatt tttgatccaa
      721 tttatcatga agataaagcc aagagagtgt cttattgata aaaataacgg atttttctcc
      781 taatactcct tttaagtggt aaaatcctat atccgaaaaa aatagcgact gattgctagc
      841 aatatctaaa gaatcagctt gttcagccaa caggttgatt gctaaaaagt ggaataattt
      901 ctttttttca taagcagaca gaggataata ctgttttaaa tcttttaaca ttttttctgt
      961 ttttataatt ataggtagcg tatacaattc cacaaaactt atctctgttg agttaaaaag
     1021 attatataaa aaaagccgaa tgtttttagg attccctgt
//
LOCUS       DAMEEU010000178         1050 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.186, whole genome shotgun sequence.
ACCESSION   DAMEEU010000178 DAMEEU010000000
VERSION     DAMEEU010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1050
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.186"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="PB779_002918"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="PB779_002918"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HDE0740377.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGEAKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          377 a          132 c          182 g          359 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaagct aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgacga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgtaggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt
//
LOCUS       DAMEEU010000179         1006 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.187, whole genome shotgun sequence.
ACCESSION   DAMEEU010000179 DAMEEU010000000
VERSION     DAMEEU010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1006)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1006)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1006
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.187"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>1006
                     /locus_tag="PB779_002919"
     CDS             <1..>1006
                     /locus_tag="PB779_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HDE0740378.1"
                     /translation="GKKISMILLNRSGNKRTYLRLKKQRYLCRACKKYFTARTYLVTP
                     FCFISKQIHYKILEELTERQSIKAIGKHCDVSVTTVQRTLSALSSDIRQNLEYLPRCL
                     LFDEFRSLSTWHGKFSFSCMDGETGKLFEILPSRRKKDLVAFFMRFSLKARLGVHYIV
                     TDMNAPYFSLVKECFPNAQVIVDRFHIVQHLNRFFDAVRKRVMKTLDQKDPIQAKQYR
                     QLKSLFKLLLKSEDRLDYNTLTKRRNFNWRLLTETEVVDRLLKISPELKTAYRYYQDL
                     LTAYQEKDPDTFFQLLRAMPGEVPLELHHIKKAFFKYEKGIRLALLKKYSNARLENLH
                     T"
BASE COUNT          302 a          210 c          191 g          303 t
ORIGIN      
        1 atggcaagaa gatctctatg attctcctga atcgtagcgg taataaacgg acctatcttc
       61 ggttgaagaa acagcgatac ctctgccgag catgtaaaaa atattttacc gctcggacgt
      121 atctcgttac cccattctgc tttatttcta agcagattca ttacaagatc ttagaagaat
      181 tgacagagcg tcaatctata aaagcaattg gtaaacattg cgatgtttct gtgacaactg
      241 ttcagcggac attgtccgcc ttgtcatcag atatccgtca gaatcttgag tatttacctc
      301 ggtgtctatt attcgatgag tttcgttctc tttctacatg gcacggtaaa ttttcttttt
      361 cttgtatgga cggtgagacc gggaaactgt ttgagatctt acctagccgc cgtaaaaaag
      421 atctcgttgc ttttttcatg cgtttttctc tcaaagcgag gttgggtgta cattacatcg
      481 taacggatat gaacgctcct tatttctcac tagttaaaga gtgttttcca aatgcacaag
      541 tgatcgtcga tcggtttcac attgttcaac atctgaaccg cttcttcgat gcggttcgaa
      601 aacgtgtgat gaaaacactt gatcaaaaag acccaataca agctaaacag tatcgccaat
      661 tgaaatcctt attcaaatta cttttaaaat cagaggatcg tttagattac aatacactaa
      721 cgaaaagacg caatttcaat tggagactat tgactgaaac agaagtagtt gaccgccttc
      781 taaagatttc tcctgaactt aaaacagctt atcgttacta ccaagacctg cttactgcgt
      841 atcaggaaaa agatccagat acttttttcc agctgcttcg agcaatgcct ggagaagttc
      901 cattggaact gcaccatatc aaaaaagcct ttttcaaata cgagaaaggg attcggctgg
      961 cattactgaa gaagtattcg aatgcacgac tggaaaatct ccatac
//
LOCUS       DAMEEU010000180         1003 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.188, whole genome shotgun sequence.
ACCESSION   DAMEEU010000180 DAMEEU010000000
VERSION     DAMEEU010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1003)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1003)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1003
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.188"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            370..1003
                     /locus_tag="PB779_002920"
                     /pseudo
     CDS             370..1003
                     /locus_tag="PB779_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          342 a          182 c          184 g          295 t
ORIGIN      
        1 gtttcaaagt tagtagagaa aatgtagtta tatatttaaa tttttaccag aaagaaatga
       61 acaccttcaa ttatctaaat ctcgaaaatg gttagatgta atcatcagga aaaacaatct
      121 taaacgaatt actattcatg gtcttagaca cacacatgct agcttgcttt tagcaagcta
      181 gtgcaaatat taaagatgtg caagagcgtt taggccactc ttctattcaa atcattatgg
      241 atctatatat tcatattaca gacaaaagaa aagaagaaac cgtagcgcaa ttcgcaaaat
      301 ataggctcta taatttatgg gactgatgaa tcaaaattga ttcttcagtc ccattgttat
      361 tttaggtata tgattcgtac attgaaagag ttgaaaaact atcttccgaa gccgtcaaaa
      421 aggaccctgc caaaagtatt gatggtggat gaatttcgtt cgcacgcttc aattgtggat
      481 aaaatgagct ttatttgtgc ggatggcgag actggaaaac tcattgatat tttgcctaca
      541 cgaaaattgt ctcgattaac acactatttt agtcgctgtg caaatcctga agcggtggaa
      601 tatttagtga cagatatgaa cgccgcctac ttccaactga caaaacgtgt cttaccaaat
      661 gcgaaagtcg tcattgattg ttttcatatc atcaaacatt tgaatcaggc gttcaatgat
      721 tttcgtgtac aagaaatgaa aagattacac cagttagggc aacgacggga agccgagaaa
      781 gtgaaaaaga actggcgctt tcttctaaaa aaccgtcaaa aaatcaatca ctatgattac
      841 aaaacatggc gcagttttcg tgcacctaaa tacccgctac tcactgaagc aatgatgatt
      901 gatcgattgc tggcattttc aacgccttta aaggacgcct atactttttt ccatgagctg
      961 accgaagcct ttagagacaa ggaatcagac ttatttttta cct
//
LOCUS       DAMEEU010000181          991 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.189, whole genome shotgun sequence.
ACCESSION   DAMEEU010000181 DAMEEU010000000
VERSION     DAMEEU010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 991)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 991)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..991
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.189"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(21..94)
                     /locus_tag="PB779_002921"
     tRNA            complement(21..94)
                     /locus_tag="PB779_002921"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(58..60),aa:Ile,seq:cat)
     gene            complement(108..181)
                     /locus_tag="PB779_002922"
     tRNA            complement(108..181)
                     /locus_tag="PB779_002922"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(145..147),aa:Met,seq:cat)
     gene            complement(209..281)
                     /locus_tag="PB779_002923"
     tRNA            complement(209..281)
                     /locus_tag="PB779_002923"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(246..248),aa:Ala,seq:tgc)
     gene            complement(301..374)
                     /locus_tag="PB779_002924"
     tRNA            complement(301..374)
                     /locus_tag="PB779_002924"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(338..340),aa:Pro,seq:tgg)
     gene            complement(384..457)
                     /locus_tag="PB779_002925"
     tRNA            complement(384..457)
                     /locus_tag="PB779_002925"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(421..423),aa:Arg,seq:acg)
     gene            complement(468..553)
                     /locus_tag="PB779_002926"
     tRNA            complement(468..553)
                     /locus_tag="PB779_002926"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(517..519),aa:Leu,seq:taa)
     gene            complement(570..641)
                     /locus_tag="PB779_002927"
     tRNA            complement(570..641)
                     /locus_tag="PB779_002927"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(607..609),aa:Gly,seq:gcc)
     gene            complement(653..725)
                     /locus_tag="PB779_002928"
     tRNA            complement(653..725)
                     /locus_tag="PB779_002928"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(690..692),aa:Thr,seq:tgt)
     gene            complement(743..824)
                     /locus_tag="PB779_002929"
     tRNA            complement(743..824)
                     /locus_tag="PB779_002929"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(788..790),aa:Leu,seq:tag)
     gene            complement(832..904)
                     /locus_tag="PB779_002930"
     tRNA            complement(832..904)
                     /locus_tag="PB779_002930"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(869..871),aa:Lys,seq:ttt)
     gene            complement(908..980)
                     /locus_tag="PB779_002931"
     tRNA            complement(908..980)
                     /locus_tag="PB779_002931"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(945..947),aa:Val,seq:tac)
BASE COUNT          260 a          283 c          235 g          213 t
ORIGIN      
        1 tgaaacttac aacgccacaa tggaccttgt aggactcgaa cctacgaccg gacggttatg
       61 agccgtctgc tctaaccaac tgagctaaag gtccaggctc ttaaaaatcg cggcggaggg
      121 gatcgaaccc ccgacctccc gggtatgaac cggacgctct agccagctga gctacaccgc
      181 gaaaaagata ttcattattt aaatgaaatg gagcctagcg ggatcgaacc gctgacctcc
      241 tgcgtgcaaa gcaggcgctc tcccagctga gctaaggccc cgtgtttaaa tttataatta
      301 tcgggaagac aggattcgaa cctgcgaccc cttggtccca aaccaagtgc tctaccaagc
      361 tgagctactt cccgtttaat taacgcgccc aagaggagtc gaacccctaa ccttttgatc
      421 cgtagtcaaa cactctatcc agttgagcta tgggcgcata tttgaaatgc cgaggaccgg
      481 aatcgaaccg gtacggtgat cactcaccgc aggattttaa gtcctgtgcg tctgccagtt
      541 ccgccacccc ggcgcgattg ctttggcaaa gcggaaaacg gggttcgaac ccgcgacccc
      601 caccttggca aggtggtgct ctaccactga gctatttccg cgtgtttaaa gatgccggct
      661 aaaggacttg aaccctcgac cctctgatta caaatcagat gctctaccaa ctgagctaag
      721 ccggcatgta aaacttaaat tatgcgggtg aagggacttg aacccccacg ccgtaaggcg
      781 ctagatccta aatctagtgc gtctgccaat tccgccacac ccgcaaaaat atgagccgta
      841 cagggctcga acctgtgacc ctctgattaa aagtcagatg ctctaccaac tgagctaacg
      901 gctcatatgg aggttaacgg gatcgaaccg ctgaccctct gcttgtaagg cagatgctct
      961 cccagctgag ctaaacctcc atggataact t
//
LOCUS       DAMEEU010000182          974 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.190, whole genome shotgun sequence.
ACCESSION   DAMEEU010000182 DAMEEU010000000
VERSION     DAMEEU010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 974)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 974)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..974
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.190"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..555
                     /locus_tag="PB779_002932"
     CDS             <1..555
                     /locus_tag="PB779_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740379.1"
                     /translation="IEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFR
                     FEGVTGRKISLKDESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKC
                     ITKRVCCICGKTGADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFK
                     NKYQIKGIKLNQKTIKKLNIGGEK"
     gene            552..>974
                     /locus_tag="PB779_002933"
     CDS             552..>974
                     /locus_tag="PB779_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740380.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKP"
BASE COUNT          368 a          169 c          186 g          251 t
ORIGIN      
        1 attgaaattc gttttattga tcctagacgt ttcaccgtac agcaacgaaa cttcatctat
       61 gcgctgatag gcgatatttt tatcgataca ggcatgccaa cggacttctg gaaggaattc
      121 ttctactttc gttttgaagg tgtcacaggg cgcaaaataa gcctgaaaga cgaatcgaat
      181 acaactgtga gtgatgccaa tgtcttagca aatatcatct tagatttcat ctttgaacat
      241 catattcctt tcaaagaagg ctatgagatt ttacctgcga atcaagaata ttacttctac
      301 aaatgcatca caaaaagagt ctgctgcatc tgtggcaaaa caggagctga catcgatcac
      361 tttgacaaag cgctaggaag acgaaagcgc aaagaagttg atcatgcaga gtacacattt
      421 gcagcactct gcagaatcca tcacacagag aagcacaaaa taggtgtgat taatttcaaa
      481 aataaatatc aaatcaaagg gatcaaatta aaccagaaaa caatcaaaaa gttaaatatt
      541 ggaggggaaa aatgacagaa catcgaagtt attatgcgat tataccagcc aacgtaaggt
      601 acgacaaaag acttaaacca aatactaagt tgttatacgg agagataacg gccttgtgta
      661 atgaaagagg cttttgttgg gcaggcaatg agtactttgc agatttatat ggtgtgaata
      721 aagagaccat atcgcgatgg gtaagtgatt tgattaagtt tggatacttg aatcgggaaa
      781 tcatttacaa agagggtacc aatcaaataa tcaataggta cctacgaatt aatcaatacc
      841 ctattgacga aaaacgcaat acccctattg acgaaaaagt caaagataat aatacatcta
      901 ttaataatac atttaataat acaaaagaat atataagaga gttaccgcct tcgaaaaaat
      961 cgaaggctaa gccc
//
LOCUS       DAMEEU010000183          943 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.191, whole genome shotgun sequence.
ACCESSION   DAMEEU010000183 DAMEEU010000000
VERSION     DAMEEU010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 943)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 943)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..943
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.191"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>943
                     /locus_tag="PB779_002934"
     rRNA            <1..>943
                     /locus_tag="PB779_002934"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          293 a          187 c          274 g          189 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact agg
//
LOCUS       DAMEEU010000184          940 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.192, whole genome shotgun sequence.
ACCESSION   DAMEEU010000184 DAMEEU010000000
VERSION     DAMEEU010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.192"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..624
                     /locus_tag="PB779_002935"
     CDS             <1..624
                     /locus_tag="PB779_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HDE0740381.1"
                     /translation="SIDLTQYNYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAI
                     CSTYLPDWRKGTDYRNNYSAFKSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSN
                     LEINSNDLATYILRYDDKIIEIHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEEN
                     IVKEMPESANDMYEKELKYFFENVVTGKENWNDLYHANEVLKIAEEK"
     gene            625..>940
                     /locus_tag="PB779_002936"
     CDS             625..>940
                     /locus_tag="PB779_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HDE0740382.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIF"
BASE COUNT          360 a          102 c          170 g          308 t
ORIGIN      
        1 agtattgatc ttactcaata taattatgat tacaaaaata tttatgttgc tgctccactg
       61 aggtataaaa atatcatgga agttgttcgt aatagtattc aaagtaaaaa agtatattct
      121 gtaagagcta tttgttctac ttatcttcct gattggagaa aaggtactga ttatagaaat
      181 aattattctg cctttaaatc tatgggggga ggagtagaat tagactgtat acatgaattg
      241 gattatatta taaacctatt tggtttccct aaatcagtaa aaaaacagtt tggtaaatat
      301 tcgaatcttg aaattaacag taatgattta gcaacatata tattgagata cgatgataaa
      361 attatagaaa ttcatttaga ttattttgga agagttccta caagaaaatt tcaattgttt
      421 actttagatg aatgtatcaa tgttgactta ttaaataata aaataagttt tgaagaaaac
      481 attgttaaag aaatgcctga atctgctaat gatatgtatg agaaggagtt gaaatatttc
      541 tttgaaaacg tagtaacagg caaagaaaac tggaatgatt tatatcatgc aaacgaagta
      601 ttgaaaatag ctgaggagaa ataaatggaa attttattta ctatttgtgg tagagctggg
      661 tctaaggggt ttaaaaataa aaatttgaaa tatttggcag gaaagcccct agtccatttc
      721 gctttagcaa tgatagatat ctatcaacaa aaacatcctg aacataattg cacgacttgt
      781 ttgaatacgg acagtaatga gttagtagaa ttgacgacta agttaaatcc gtctgtgaaa
      841 attgtagaac gtaaacctga attagctaca gatactgtag ggaaaattga agtgatacgt
      901 gattcattct tacaactaga aagagaagat aatatatttg
//
LOCUS       DAMEEU010000185          940 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.193, whole genome shotgun sequence.
ACCESSION   DAMEEU010000185 DAMEEU010000000
VERSION     DAMEEU010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 940)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 940)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..940
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.193"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            172..459
                     /locus_tag="PB779_002937"
                     /pseudo
     CDS             172..459
                     /locus_tag="PB779_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            473..904
                     /locus_tag="PB779_002938"
     CDS             473..904
                     /locus_tag="PB779_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740383.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          358 a          135 c          197 g          250 t
ORIGIN      
        1 gctaaatact taaaaacgca tgtagaagct attgatggta aagaagcatt ggtgcagaca
       61 gatggagacc aagccattgc aggacataag aatttttcag gttctgtaac aatcaataat
      121 aaacgtgttt tgacgactga tgataacaga tatgaagtgg taaatctggt tgtcactaac
      181 ggtaatacag ggacagcaaa gctttatcgt gaaggaaaaa cagtttctat atattttgtg
      241 gctttaaacg gaaaaagtag tggcgggaat gattcggtta ttttaactgt tccagaaggc
      301 tatcggacac caattagttt tgaacaactg gttgggtcaa tagaccgttc tactttgaac
      361 agtgctcaac tatctattgg cgcagacgga gccattaaat ggagaagaaa ttcaagttat
      421 ggatcagctt attcatttgt tatcacttat tcaatttaag ggaggaaatc taatgaaagt
      481 agtttacaaa tcaatcaagc cttacggatt cgagcaaatc attttgaaca atcaagaaaa
      541 tatccctgaa aactgtacag agattaaacc accagttcct aactggagac caagatttga
      601 ttttgataaa aaacagtggg ttgagttagc tactgaagaa gagaaaaaag ggaatgctgt
      661 tgatagcgta gatgaattgg ctaatattaa ggcattatac gaaacgctga aggcagaaaa
      721 tgatgaattg aaacagctaa attctaaagc aatgctaaac aatgtagcaa tcaagcaaga
      781 aaatgtctta ttgaaagaaa agtcagaaag tttagcgcag ttgaattcaa aaacgatgct
      841 tgcttctgta caaaatacca aggaaatcga agaaatcaaa aaacaattac aaggtgggaa
      901 gtaacatgta ttcatatgaa gatatcaaac taatgtatga
//
LOCUS       DAMEEU010000186          887 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.194, whole genome shotgun sequence.
ACCESSION   DAMEEU010000186 DAMEEU010000000
VERSION     DAMEEU010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.194"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..>887)
                     /locus_tag="PB779_002939"
     rRNA            complement(<1..>887)
                     /locus_tag="PB779_002939"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          191 a          274 c          196 g          226 t
ORIGIN      
        1 agcacgtgtg tagcccaggt cataaggggc atgatgattt gacgtcatcc ccaccttcct
       61 ccggtttgtc accggcagtc ttgctagagt gcccaactga atgatggcaa ctaacaataa
      121 gggttgcgct cgttgcggga cttaacccaa catctcacga cacgagctga cgacaaccat
      181 gcaccacctg tcactttgcc cccgaagggg aagctctatc tctagagtgg tcaaaggatg
      241 tcaagacctg gtaaggttct tcgcgttgct tcgaattaaa ccacatgctc caccgcttgt
      301 gcgggccccc gtcaattcct ttgagtttca accttgcggt cgtactcccc aggcggagtg
      361 cttaatgcgt tagctgcagc actgaagggc ggaaaccctc caacacttag cactcatcgt
      421 ttacggcgtg gactaccagg gtatctaatc ctgtttgctc cccacgcttt cgagcctcag
      481 cgtcagttac agaccagaga gccgccttcg ccactggtgt tcctccatat atctacgcat
      541 ttcaccgcta cacatggaat tccactctcc tcttctgcac tcaagtctcc cagtttccaa
      601 tgaccctccc cggttgagcc gggggctttc acatcagact taagaaaccg cctgcgctcg
      661 ctttacgccc aataaatccg gacaacgctt gccacctacg tattaccgcg gctgctggca
      721 cgtagttagc cgtggctttc tggttagata ccgtcaaggg atgaacagtt actctcatcc
      781 ttgttcttct ctaacaacag agttttacga tccgaaaacc ttcttcactc acgcggcgtt
      841 gctcggtcag actttcgtcc attgccgaag attccctact gctgcct
//
LOCUS       DAMEEU010000187          880 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.195, whole genome shotgun sequence.
ACCESSION   DAMEEU010000187 DAMEEU010000000
VERSION     DAMEEU010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.195"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            147..848
                     /locus_tag="PB779_002940"
     CDS             147..848
                     /locus_tag="PB779_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HDE0740384.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
BASE COUNT          318 a          154 c          146 g          262 t
ORIGIN      
        1 caataccatt gtatattttt tacataataa caaattatat ttgtaaagta ttaaaacttg
       61 tttctaatgt tggtatgtta aaactttaca aattctttaa aaaaagtgac aataaatata
      121 gtgaacaata aggagaggac tttttaatgc gtgttaataa aatcgatttt cacttttcaa
      181 aactcagata tcaacctgat tttgaacatt tctcggatga agagttccaa cagatcaagg
      241 aacatactgt tcttcgttct tataaaaaag gacagatcct tttcgacgat ggtgatccca
      301 gacaacggtt gtatatcttg accaaaggac tcgttcgttt agaacgttat gatgaaagtg
      361 caacttatta ctactatgac tatgtgaata caaataacct ttttcctatg tcaggaatgt
      421 ttggagaaga gacctacact tatacagctc aagcgatgac tgatattgaa acattctacc
      481 ttcctgtttc ctactatgaa aaattagcac gaaaaaatcc cgaacagttg atctatatga
      541 tacaaaaaat ttctaaagta gttgaaatac atgaattgcg tatccaaatc ggattgacct
      601 ctagcgcctt tgaccgggta aaacaaaatt tattcatttt gaaagaagaa ttgggcgtac
      661 caacaaaaga tggtcatatc accattcctt atccgatcac cttaaaagaa ttagcagtga
      721 atagcggcac gacacgtgaa actgctggac aagtaatcaa acaactacgt gattccgggc
      781 tgttagatta tgacaaaaag cgttttactt tctgtaagac agctactact ccagctatga
      841 gagaataacg cgaacaaaaa taagcagtga ccctgataaa
//
LOCUS       DAMEEU010000188          877 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.196, whole genome shotgun sequence.
ACCESSION   DAMEEU010000188 DAMEEU010000000
VERSION     DAMEEU010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.196"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(71..>877)
                     /locus_tag="PB779_002941"
     CDS             complement(71..>877)
                     /locus_tag="PB779_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDE0740385.1"
                     /translation="TYYYQAKPIENESDLEEIVQEEFIRNRKAYGTRKLKKCLAKRGL
                     QLSRRRIGRIMKRRGLTSTYTIAHFKGQRTACNEAKTTNVLDRTFTQEQPLEAIVTDL
                     TYVRVRKKWHYICLILDLFNREIIGYSCGEKKDASLVKEAFGRIPYSLTDVKLFHTDR
                     GKEFDSQTIHEILNGFGITRSLSRKGCPYDNAVAESTHKSVKVEFVHQYQFETLAQLR
                     LELFDYVHWWNYLCLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          232 a          208 c          167 g          270 t
ORIGIN      
        1 tggctccgat tgcccttgac aatgagcatc ctcggatctg attttctccg gcagaagcac
       61 aatcattcaa ttacgctgcc tctccagagg tatcagatcc gcgctcatta tcaaggattc
      121 gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc atacgccaac gtgccatgta
      181 agcatagata gttccaccaa tgcacataat caaacaattc tagacgtagc tgtgccagtg
      241 tctcaaattg gtattgatgc acgaattcta ctttgacaga tttatgggtt gattccgcaa
      301 cggcattatc atacggacaa cccttcctac tcaatgaacg agtaattcca aaaccattca
      361 gaatctcatg aatggtttgg ctatcaaatt cctttccacg gtctgtatga aaaagcttga
      421 cgtctgttaa agaatacggt atccgtccaa aggcttcttt taccaatgag gcatctttct
      481 tctcaccaca ggaataacca ataatttctc gattaaacaa atcaagtatt aagcagatat
      541 aatgccactt tttcctcacg cgaacataag taagatccgt aacgatggct tccaatggct
      601 gttcttgtgt aaaggtccga tctaatacat tcgttgtttt cgcttcatta caagctgttc
      661 gttgcccttt aaaatgagcg atcgtatagg tagatgtcaa tccgcggcgt ttcatgattc
      721 gaccgattcg gcgccgactg agttgaagcc cacgctttgc taaacacttc ttcaattttc
      781 gggtaccgta agcctttcgg tttcgaataa actcttcctg aacgatctct tctaagtcgg
      841 actcattttc gatcggtttc gcttgataat agtaggt
//
LOCUS       DAMEEU010000189          876 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.197, whole genome shotgun sequence.
ACCESSION   DAMEEU010000189 DAMEEU010000000
VERSION     DAMEEU010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 876)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 876)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.197"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..434)
                     /locus_tag="PB779_002942"
     CDS             complement(<1..434)
                     /locus_tag="PB779_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740386.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYTTNNQNGTVALIDSKFIKVPKLKSLVRIKLHR"
     gene            complement(451..855)
                     /gene="tnpA"
                     /locus_tag="PB779_002943"
     CDS             complement(451..855)
                     /gene="tnpA"
                     /locus_tag="PB779_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HDE0740387.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLWKE
                     MFWSKSFCLLTTGGAPIDVIKKYIQNQGNNHK"
BASE COUNT          263 a          143 c          137 g          333 t
ORIGIN      
        1 tgtctatgaa gcttaattct tactaatgac ttcaatttag gaactttgat gaatttacta
       61 tcaatcaaag caactgtacc attttgatta ttcgttgtat aactctgaac aggatttttc
      121 ttacttttga aacgtggaaa tccaacggat ttatcccgaa aaaaattctt gtatgcttta
      181 tctaaattaa gttgggcatt ggctaaagca aggctatcaa tttctttcaa aaacggaaat
      241 tctttcttgt atttagctgg tgtcggaaaa gtcatttttt tagaagaatc atttttaact
      301 tcttcatacg ccttttttcg gtcatcaagc attagattgt agaccttacg gacacaacca
      361 aaagatttgg caaagaagat ttcttgttcc tctgttggat agattctgaa tttgtatgct
      421 tttagttgtt ccataaagtt cacctacttt ctatttatga ttgtttcctt gattttggat
      481 atacttctta atcacatcaa ttggtgcgcc accagttgtc agaagacaaa aacttttaga
      541 ccagaacatt tctttccaaa gaaattgttt gactcttgga aagtcacgtt ttatcaatct
      601 tgagctggca cttttatagg cattgatgaa ttttgtcaat tctgttttag gttgagcttt
      661 gaacataata tgaacgtggt ctttatcatg attccactcc actaaagtaa tgtgatacga
      721 ttctgaaatt ctttcaaaag tagttttggc ataatcagat atttcatcat caatcacttg
      781 tctacgatat ttcgttacta aaacaaggtg gtaataaaga agaaatactg aatgattatt
      841 tgtatctaat tccatgttat atcaactcat ttcttg
//
LOCUS       DAMEEU010000190          806 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.198, whole genome shotgun sequence.
ACCESSION   DAMEEU010000190 DAMEEU010000000
VERSION     DAMEEU010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.198"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            349..804
                     /locus_tag="PB779_002944"
     CDS             349..804
                     /locus_tag="PB779_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HDE0740388.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
BASE COUNT          275 a          145 c          126 g          260 t
ORIGIN      
        1 aaaacagaag ttctataagt tataatcata gttgttaggt gattcatcta gtaaaaacac
       61 cagatttcaa atttcacaca atttaaacta gatcaatcat caaccttctt caaattgtta
      121 gaaccctttc ccgaggagct gcagcataag caaaaaaaca aacaggaagc caaatggcta
      181 agacattttt tctattagtc tagttgcttc tcgtcgcaag tttaagactt tagaaagtta
      241 tttctaatga tgtttgggtt gttttgatca atgcttatgc acagctcctt acctattatt
      301 tatctcaaca gatctaacaa attaatggac tatttaagga gtttttttat gcttacgatc
      361 tattcttctc gcacacatag ttaccatctg atggcaaact ggctgaaaga ccatcaaatg
      421 ccttacagag aacgaatttt cacacctaaa cagcctttaa caaggaaaga gatattttat
      481 ttattgtcat taacagaaaa cggatttgac gatctattag ctaaacgctc gattgattat
      541 aaaaatttga aagaccaaat cgaccaatgt acgacctcag agcttgtcga tctgatcgtc
      601 tcgcatttta ctttgttaca acgtcccatc attactgacg gaaagaaatt attagtcgga
      661 ttcaatgaag atagcatgcg tctttttatc cctgtacaat ggcgcagaag tcaactgaaa
      721 tctgtctata acgattttac atgggtaagc aatctagaaa attctacgga tttagatgat
      781 gaatttttaa attattatat ataaaa
//
LOCUS       DAMEEU010000191          800 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.199, whole genome shotgun sequence.
ACCESSION   DAMEEU010000191 DAMEEU010000000
VERSION     DAMEEU010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 800)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 800)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..800
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.199"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(324..524)
                     /locus_tag="PB779_002945"
     CDS             complement(324..524)
                     /locus_tag="PB779_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0740389.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          287 a          125 c          127 g          261 t
ORIGIN      
        1 tctttttcgt tgctttgctc ataaaaatct gcatattcat cactaatatt ttttctaata
       61 aattcttcca tcataaagat cacctcgaaa agagtatacg aacaaacgtt ctttttgtaa
      121 aggtggaatt tattatacta aataaatagg tgaacaagta cttgtgccaa attatgtgcc
      181 aaaaaaaatc gaatttaata aaacacaaac aaaaagaaat cctattatga taacatttct
      241 tataataaca aacacaacag aagacgtgta atagttagtc aggaacgtac aaataacccc
      301 tgtatccttt gcggtacagg gggttatttt gtataagtag acattgtagt ttctaaactg
      361 ctatgtccta aacgtttcga tacgctaagt atatttactc cttgataaag taaaatagat
      421 gcatgcgtat gtcttagtcc atcaataaac agtcgaagag aaaataggga aaaattgatt
      481 actaaagaaa aacttactag gtcgacggtg tagttgattt tcatacttca atagattcga
      541 attaaacgat ttcgattggc ttataccagt cctatccaac gaaagatata tcgttcttaa
      601 ctctagcggt ataacttgaa gctttacgta aagccaatgg gaatgaactg gagatgactt
      661 tttattattt ttagtaatag ctgatgggtt aatacttaca actttccttt tcaaagtacc
      721 atataaaaaa acggtggggt tgtttagcga aataaaggat ctaagccaat agcttagatc
      781 ctttattcta tgctttatat
//
LOCUS       DAMEEU010000192          790 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.200, whole genome shotgun sequence.
ACCESSION   DAMEEU010000192 DAMEEU010000000
VERSION     DAMEEU010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.200"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            24..716
                     /locus_tag="PB779_002946"
     CDS             24..716
                     /locus_tag="PB779_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HDE0740390.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT          282 a          151 c          159 g          198 t
ORIGIN      
        1 tgaaaaaaag gattttagta acaattggtc tagctttttt gttagctggt tgtaccaacg
       61 ggaatgaatc gaaaaaagaa tcaacaaaag aaacagcgaa agcaacagtt gcaactacta
      121 caacaactag cacagagagc aagtcaactg cagcaagtac agaaacagca gatacctcta
      181 cttcgtcaga gtcttccaaa acgactgaaa caactcaaac atctacttca agttcttctg
      241 tagaggcttc atcttcctct tcagaaagca gcgaacaagt tgaacaaaca ctgtggaatg
      301 cagacaaatc cgcacaatta gaggcattta tgaccaaatg gggccaaaca atgggacaac
      361 aatacaaaag ttatacgaat caaatgagtg tggacttata tggtcttaaa gtccctcaag
      421 ctattttgaa cggggagtgg aagatggcta ttggtggagt gcctgtttct gcagaatggt
      481 cagaaagtgg gacaggtcaa gcagactatc aaatcacagc cgtctattcc gatgcagaga
      541 cagaaccata tctgaaaaag cacgtctatc tattcgggtt tcagcaaaat cagccaaaag
      601 tattggtgac acaacaaaat caggggaatc ccgataatta tctttacttc aacgagacag
      661 cgaataatga attgaaaaat ggctttaatc aaatcgttta tggacaagca aattaatgag
      721 ataaacaagg ggttgtgaca tgtcttttat cacaacccct tgctcagttt atttgttagt
      781 cttttatttt
//
LOCUS       DAMEEU010000193          780 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.201, whole genome shotgun sequence.
ACCESSION   DAMEEU010000193 DAMEEU010000000
VERSION     DAMEEU010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 780)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 780)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..780
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.201"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(321..620)
                     /locus_tag="PB779_002947"
     CDS             complement(321..620)
                     /locus_tag="PB779_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDE0740391.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT          257 a          133 c           80 g          310 t
ORIGIN      
        1 tcctaatgta aattattttt tcgcatatat tcattttatt ttacttattg ctttcatttt
       61 ttcaatctat atttccaatt tttaacttac aaaaatgcaa cattaataaa taacgatagt
      121 ttcataaaat acacttttaa ttaacattat tagtttatac tagctgtttt tgtgttaatt
      181 aaaggataaa atacaatata aagaaacatc tgtttcttta tttagaataa aaaaatacag
      241 actctgttca aataaatgaa cctagcctgc attatgagat tgactatact ttttaattca
      301 ttgagatgaa taactcgttt ttataaatgc ccaaaagtaa tcggtgccga agccattcct
      361 cgacctaatt ctttttcaaa ttttcctatt gttgatatct ccatataaaa cggtgatact
      421 ggtttagaca attctcccct gattgctaac ggacgtaaac tacgttccaa attatttatg
      481 actttaggat aatactgacc tttttctaag cctgtctttg cgtctatcaa aagtatacgt
      541 tccttttctt tgatctctgg atttaaaacg agatcatata attttagtac catgttttct
      601 atttcttcac ttttagacat cacgatttcc tcccaaaaat atatttcttc ccactacatt
      661 ctataaacaa agtatacgct acatctagat ttttttaaat cattactgga ttgttaaaac
      721 ctttcaatac actgttatgg caacgatttt tattttaaaa acattctaaa ttaaatcagt
//
LOCUS       DAMEEU010000194          765 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.202, whole genome shotgun sequence.
ACCESSION   DAMEEU010000194 DAMEEU010000000
VERSION     DAMEEU010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.202"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..660
                     /locus_tag="PB779_002948"
     CDS             <1..660
                     /locus_tag="PB779_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740392.1"
                     /translation="YISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDNNKFT
                     SKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTDFLNK
                     LSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRKIIKV
                     DKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLHSMGL
                     A"
BASE COUNT          284 a          114 c          143 g          224 t
ORIGIN      
        1 tatatttctt tgttgtgtaa agaagaaatt atcgaattac ctaaaactaa ttccacaatt
       61 ggtattgact taggtattat ggactttgcg attctttctg atggacaaaa aattgataat
      121 aataaattca cgtccaaaat ggaaaagaaa ctaaagcgtg aacaacgcaa attgtctagg
      181 cgtgctttat tggctaaaaa taaaggtacc aatctatttg aagctaaaaa ttatcaaaaa
      241 caaaaacgca aagtagctag attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat gatcaaaaat cacgatatta tctgtattga agacttaaac
      361 acaaaaggta tgttgcgaaa tcataaatta gctaaaagta tttctgatgt ttcttggtca
      421 aagtttgtga ctaaattaca atacaaggct gactggtatg gacgaaaaat catcaaagta
      481 gataaatggt ttccgtctag tcagatttgt tcagagtgcg gacataaaga tggcaagaaa
      541 tctcttgaaa ttcgagaatg gacttgtcct gtttgtcata ctcatcatga tcgtgatatc
      601 aatgctagta tcaatattct gaccgaaggt ctaagactac attctatggg attggcttag
      661 atccaatcat caagaaccgt aggaactacg gggatagctt ggtaaataag agacaccgct
      721 gttagtaaag aaatacgcta tcaagtatgc tctattccca agaag
//
LOCUS       DAMEEU010000195          763 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.203, whole genome shotgun sequence.
ACCESSION   DAMEEU010000195 DAMEEU010000000
VERSION     DAMEEU010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.203"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            159..>763
                     /locus_tag="PB779_002949"
     CDS             159..>763
                     /locus_tag="PB779_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HDE0740393.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFA"
BASE COUNT          259 a          114 c          128 g          262 t
ORIGIN      
        1 tacgcctaat ttgtgtctct cagggcaatt ctaagaacgt ttcaagagat agcgacacta
       61 tcgttatcga aaaaggcgaa aacctatctc attttctgct aatgtaagtt ggtttagctt
      121 ttgttaatat gactttatga aaatggaggt aattaaatat gatttttcct aaagttaatg
      181 aagcaagctt gaataaagga tccttttttc atatctatga aaacgaagat tttgaactgt
      241 ataatatcct ttcacaaaaa gaggtcatcg aaaaccaaat aatctgccat ccaattattt
      301 acaaatctat tttcaagtat gcattttttg cttccaatga ttttcaaaga atggagatta
      361 ccgactgtat attcgaaaac tgtgattttt caggctgtat attgacaaaa agcatgttgc
      421 atcgcgtgaa atttgtcaat tgtaaattaa caggtactaa attgatggaa agttatattg
      481 ggaacacgtt attcgagaat tgtaaaatgg actatgtaaa tttatctggt tcaaacataa
      541 aagaaagtac ctttgagcac tctgtcttat caagcgcaga ttttgtagac tgttccctca
      601 ctaaaataat gttttctact aatgatttag aaaatgctag cttttttgat actgatttaa
      661 aaaatatcga tttaagtagc aactcctttg aaatgattga agtacgctcg gaacatctaa
      721 aaaattgtac gcttaatcag ttgcaagcac ttggttttgc tag
//
LOCUS       DAMEEU010000196          759 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.204, whole genome shotgun sequence.
ACCESSION   DAMEEU010000196 DAMEEU010000000
VERSION     DAMEEU010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 759)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 759)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..759
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.204"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>759
                     /locus_tag="PB779_002950"
     rRNA            <1..>759
                     /locus_tag="PB779_002950"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          213 a          170 c          221 g          155 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattc
//
LOCUS       DAMEEU010000197          742 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.205, whole genome shotgun sequence.
ACCESSION   DAMEEU010000197 DAMEEU010000000
VERSION     DAMEEU010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.205"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            178..381
                     /locus_tag="PB779_002951"
     CDS             178..381
                     /locus_tag="PB779_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucocin A/sakacin P family class II
                     bacteriocin"
                     /protein_id="HDE0740394.1"
                     /translation="MKHCVILGILGTCLAGIGTGIDVDAATYYGNGLYCNKEKCWVNW
                     GQSWSEGLKRWGDNLFGSFSGGR"
     gene            381..731
                     /locus_tag="PB779_002952"
     CDS             381..731
                     /locus_tag="PB779_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HDE0740395.1"
                     /translation="MTSINIDHTKKVIHELYNSLMTRPNQTKALLDITDVLFQVYKKI
                     DTAKYPEILVNKLVNYIYIVGFDNKIRFIDNDEKLLIELGDISKKAGINSKYKANFTD
                     KSQFYSYSETMPQR"
BASE COUNT          300 a           80 c          120 g          242 t
ORIGIN      
        1 gacttccttt tttgtatgga ttttttcatt tacacaaaat attttacact ctcgtcaatc
       61 attgttatat aataaaatgt tatataataa aattactaat gatatttaat attacaagca
      121 atcttaagaa attcgaaaag gaaaaaatga ttatgaaaaa gaaagaaaaa gaaagtattg
      181 aaacattgtg ttattctagg aatattagga acttgtctag ctggcattgg tacaggaata
      241 gacgttgacg cagctactta ctatggaaat ggtctttatt gtaacaaaga aaaatgttgg
      301 gtaaattggg gacaatcatg gtcagaaggg ttaaaacgtt ggggagataa tctttttggt
      361 agttttagtg gaggacgata atgacttcaa taaacattga tcacacaaaa aaagtcatac
      421 atgaattata caatagttta atgacacgac ctaatcagac gaaagcatta ttagatatta
      481 ctgatgtttt atttcaggta tataaaaaaa ttgatacagc aaaatatcct gaaattcttg
      541 taaataaatt agttaattat atttacatcg tgggttttga taataaaata cgctttattg
      601 ataatgatga aaaattatta atagaattag gggatatctc taaaaaagct ggaattaata
      661 gtaaatacaa agcaaacttt acagataaat cgcaatttta tagttattca gaaacaatgc
      721 ctcaacgata aaatatagta ta
//
LOCUS       DAMEEU010000198          730 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.206, whole genome shotgun sequence.
ACCESSION   DAMEEU010000198 DAMEEU010000000
VERSION     DAMEEU010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.206"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..540
                     /locus_tag="PB779_002953"
     rRNA            <1..540
                     /locus_tag="PB779_002953"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
     gene            635..>730
                     /gene="rrf"
                     /locus_tag="PB779_002954"
     rRNA            635..>730
                     /gene="rrf"
                     /locus_tag="PB779_002954"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          199 a          152 c          214 g          165 t
ORIGIN      
        1 agtcgagcag ggacgaaagt cgggcttagt gatccggtgg ttccgcatgg aagggccatc
       61 gctcaacgga taaaagctac cctggggata acaggcttat ctcccccaag agtccacatc
      121 gacggggagg tttggcacct cgatgtcggc tcgtcgcatc ctggggctgt agtcggtccc
      181 aagggttggg ctgttcgccc attaaagcgg cacgcgagct gggttcagaa cgtcgtgaga
      241 cagttcggtc cctatccgtc gcgggcgttg gaaatttgag aggagctgtc cttagtacga
      301 gaggaccggg atggacttac cgctggtgta ccagttgttc tgccaagggc attgctgggt
      361 agctatgtag ggaagggata aacgctgaaa gcatctaagt gtgaagccca cctcaagatg
      421 agatttccca tttctttaag aaagtaagat ccctgagaga tgatcaggta gataggtcag
      481 gagtggaagt acagtgatgt atggagcgga ctgatactaa tcgatcgagg acttaaccaa
      541 taggttaaaa gaaaagaact cggaaaaaaa cttatgtgac ttcaaatcca gttttgagtg
      601 aacaaaattt actcaataaa agataacacc acagtgtggt ggcgatagcg agaaggatac
      661 acctgtaacc atgccgaaca cagaagttaa gcttcttagc gccgattgta gtgaggggtt
      721 gccccttgtg
//
LOCUS       DAMEEU010000199          695 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.208, whole genome shotgun sequence.
ACCESSION   DAMEEU010000199 DAMEEU010000000
VERSION     DAMEEU010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 695)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 695)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..695
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.208"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(82..636)
                     /locus_tag="PB779_002955"
     CDS             complement(82..636)
                     /locus_tag="PB779_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HDE0740396.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADVAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
BASE COUNT          209 a          144 c           69 g          273 t
ORIGIN      
        1 acttccgaaa attcagttat cttcattaat ctcaccttct aagttttcat tatacacaaa
       61 aaatatatcc taatatctca attagcctcc caatttaaaa ccacgtaacg atgcccctat
      121 ttcatcttca gttataccaa tgtacctttt tgtaattgct tgcgagctat gattaaaaat
      181 aaacattaag gtagcaatgt ctctagtttt cttgtagtag tgatacccaa aagtttttct
      241 taatgtatgt gttcctatat catctcttcc taatttttct gctacatctg catatatctg
      301 atagacacga tcccttgtta tatgtcgacc ttgttgccga cttggaaata accaatcatt
      361 ttcttcttta ccttcagtat ataataaaat ctcttctctc aaattatcta taaaaatcgg
      421 ttttcgctta cctgttttat gttcaacaat aataggctta cttttacctc gtatgtctcc
      481 aacttttaat cctataatat ctgacatacg taacccatta ttgattccaa acaaaaataa
      541 aaaactatct ctttctggat tacttgttct tcttagccaa aactgaaaat cttgtatctc
      601 ttcatttgtc cttaacggtt gtacattata gctcactatt gtttcccttc ttaaaaatat
      661 tctgagttca tgattatata tatattttac cataa
//
LOCUS       DAMEEU010000200          682 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.209, whole genome shotgun sequence.
ACCESSION   DAMEEU010000200 DAMEEU010000000
VERSION     DAMEEU010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 682)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 682)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..682
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.209"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>682
                     /locus_tag="PB779_002956"
     CDS             <1..>682
                     /locus_tag="PB779_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HDE0740397.1"
                     /translation="ALEYYQQYKKNKSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIV
                     GRAAFPISCSARTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKD
                     YSQFSNEFGHLEGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFE
                     SVPKNLFKSITFDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGL
                     LKSMDFNSV"
BASE COUNT          229 a          116 c          138 g          199 t
ORIGIN      
        1 gccttagaat attatcaaca gtataagaaa aacaaatcaa actgtggtag acgtccgctt
       61 gttttacccg aggaacaatc agaatatatt caaagaaagg ttgttcaagg atggacaccc
      121 gatgtgattg ttggtcgtgc agcgtttcct attagttgtt ctgctcgtac catttatcgt
      181 atgttcaaaa aggggctatt tgattcttct gacttaccga tgaaaggcaa gcgtaaaccg
      241 aatggacatc aagaaagacg tggaaaacaa actttccgcc gctctattca tgaacgtgaa
      301 aaggattata gccaattctc aaatgagttt ggtcaccttg aaggtgacac tatcgtaggt
      361 ctgaaacata aaagtgctgt aattacctta gttgaacgat tatcaaaagt tatcatcaca
      421 ttgaaaccgt gtggtagaca agcgattgat attgaaaaaa aattaaatca atggtttgaa
      481 tctgtaccga aaaacctatt caaatccatc acttttgatt gtggaaagga attttcaaat
      541 tggaaacaga tcagtaatgt caatgatatt gccatttatt tcgctgatcc aggaacgccg
      601 tctcaaagag gcctaaacga gaattctaac ggattgttac gtagagatgg tttattgaaa
      661 tctatggatt tcaattcagt ag
//
LOCUS       DAMEEU010000201          662 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.210, whole genome shotgun sequence.
ACCESSION   DAMEEU010000201 DAMEEU010000000
VERSION     DAMEEU010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.210"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..446)
                     /locus_tag="PB779_002957"
     CDS             complement(<1..446)
                     /locus_tag="PB779_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740398.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRK"
BASE COUNT          196 a          118 c           90 g          258 t
ORIGIN      
        1 aactttctct tttcaaaaaa aatttgatat ttttttagat ttctttttag tctttgtaat
       61 actttataag ccacagaata actcacgtga tgctgtttag caaaattttc tactgagata
      121 tatttttcct gaaagaaagc caataccatt ttcatagata aagaatccgt tatataacga
      181 gataacagag ctttgctaga acattttcca ttaatttcca gacatatatc caattcactg
      241 acggttactc gcaaattttt ctctagatcg aacttttgta aatcatgttt cagcttatcg
      301 atcgtttttt tcaagagaaa tgtcgatagc gacaactctt cttgaacatt cgatattgac
      361 tctgataaat ttgagcttgc ttctaaatat ttaagtaatg aataacttct gtgatcttct
      421 ttgcttaaaa aaaactcata attcattagt catcagctct ttctacgtat attactttcc
      481 atgcattcac caactagctg gggataaaac tgatttcctg gatccgagtc actgttgtca
      541 gcgattcttg tttgtataat atacatcgtc ctgtcttttt tttaacattt tggagagcgt
      601 tttatttggc ctttctcgcg atcaaacctg ttattagaat tatatcattt actagtatgc
      661 at
//
LOCUS       DAMEEU010000202          658 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.211, whole genome shotgun sequence.
ACCESSION   DAMEEU010000202 DAMEEU010000000
VERSION     DAMEEU010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.211"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>658
                     /locus_tag="PB779_002958"
     CDS             <1..>658
                     /locus_tag="PB779_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HDE0740399.1"
                     /translation="FPSRSRFTRLSSNLAYTIKIIRYFFIKKLTKGELVGIIDSFPSP
                     LCKPVRNRQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITNPGVHDVK
                     VLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLDHSLLGKQ
                     RKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEGTLRYSLG
                     Y"
BASE COUNT          229 a          119 c          114 g          196 t
ORIGIN      
        1 ctttcctagt aggagtcgat tcactcgctt aagttcaaac ttagcttaca ctatcaagat
       61 tattcgatac tttttcatca agaagctcac caaaggtgaa ctagtcggaa ttatagatag
      121 ttttcctagt ccattatgta aaccagttag aaatagacaa gcaaaactat tgaatcaaat
      181 agccaaagtt ggctataact caacaaaaaa atcttatttt tatggtctta aaattcatat
      241 gatcgttact aagactggct ttccgattac ttactcaatc acgaatccag gtgtccatga
      301 cgtgaaagtg ttagagactt tatcggaaga agcgaatctt cccaatatcc taggggacaa
      361 aggatatatt agccataaaa tccatgaaaa gcttgccctt aagggcatta ctatatccgt
      421 tccgccacgt aaaaacatgg ataaatcaga aaaactagac cacagcttac ttggaaaaca
      481 aagaaaaaca gttgagactg ttttttcttc cttagaaaaa ttaggttgtc aaaatttcaa
      541 ctcacgttct gttaaagggc tagagagtag atttgaaagc atattactgg cttacagtgt
      601 tctattaagt cgagcacaac gacgttttga aggaactttg agatattctt taggatat
//
LOCUS       DAMEEU010000203          645 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.212, whole genome shotgun sequence.
ACCESSION   DAMEEU010000203 DAMEEU010000000
VERSION     DAMEEU010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..645
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.212"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>645
                     /locus_tag="PB779_002959"
     CDS             <1..>645
                     /locus_tag="PB779_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK signal domain/LPXTG anchor domain surface
                     protein"
                     /protein_id="HDE0740400.1"
                     /translation="IFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKW
                     PEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDASEGIKNKEDL
                     PKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG
                     EKVEVGGTVDLTDNVTNLPTLPEGTTVTDVTPDGTIDTNTPGNYEGVIEVTYPDG"
BASE COUNT          254 a          105 c          150 g          136 t
ORIGIN      
        1 atcttcaccg caggggaagg aacaagtatt gaaagtggaa caacggtctt tgcagtgaaa
       61 gacggcgtaa gcttaccaga agataaactt ccagtgttga aagcaaaaga tggttataca
      121 gatgcgaaat ggccagaaga agcaactcaa ccaattacag cagatgatac agaatttgta
      181 tcaagtgcaa caaaactgga tgataaatct gacgctgaca aatataatcc tgaaggtcaa
      241 aaagtgacta cagaattgaa taaggaacca gacgcatctg agggaattaa gaacaaagaa
      301 gatttaccaa aagatactaa gtatacttgg aaagaaaaag tagatgttag cgcagctgga
      361 aataaaaaag ggactgttgt agtgacatat ccagatggat catctgatga agttgaagta
      421 gatgttacag tgacagacaa tcgttctgac gccgataaat atgagccaac agtagaaggc
      481 gaaaaagtag aagttggagg cacagtagat ctaacagata atgttactaa cttgccaaca
      541 ttaccagaag gaacaacagt aacagatgtc actcctgatg gtacgattga taccaacaca
      601 ccaggtaatt acgaaggggt tatcgaagta acgtatccag atggt
//
LOCUS       DAMEEU010000204          609 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.215, whole genome shotgun sequence.
ACCESSION   DAMEEU010000204 DAMEEU010000000
VERSION     DAMEEU010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 609)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 609)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..609
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.215"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
BASE COUNT          222 a           78 c          111 g          198 t
ORIGIN      
        1 taattatgtg attgaatgcc gatttttgtt acgcgctatt tttaattatc tgtaagaaga
       61 ataattttat tttactcata ttcgttttca ctttgaagaa gtaaattgca atttcttata
      121 agttaagcag ctatgcaaaa ggctatttat tctattgtga aatataagat gtagttgaaa
      181 caggatatat agaatcaaaa tacgaatctt attttgattt ttctagtttt ttgaaaaaag
      241 caccctttga tcgttgtatt agtggaaaag agaaaaagga gcatacttat catgtcacaa
      301 aactacaact aaatatctaa acaacaccaa tttgatgcct attgaaaaaa agtattgcga
      361 aatgaagcca agtctattag aaaatgaaat aatagaataa aagaaaatgg gaaaccgctg
      421 aatgatgtaa atgaaggtaa gtatccacga actaattttg atgaacaaga tatctatttt
      481 ttatttgtat tggagatact agtttaacag aattaggcag aagtcgccca tcctctatag
      541 gtgggtgatg aatgccgttc ggtatgaggg ttaccgttgg taactcgaag accgacaact
      601 aaggcgtat
//
LOCUS       DAMEEU010000205          572 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.219, whole genome shotgun sequence.
ACCESSION   DAMEEU010000205 DAMEEU010000000
VERSION     DAMEEU010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.219"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>572
                     /locus_tag="PB779_002960"
     CDS             <1..>572
                     /locus_tag="PB779_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740401.1"
                     /translation="AMGVFFLYYVFFENKNTKKHKIKIIVSLILIFMGLKRIELLALS
                     GAILVYYVLLKWGKKIQIRALVCTICATVISLVFIYIIDTGILALLMSNLGITDDGAR
                     LSFYLYSSKFYELGLGYVGTGWTWFSKYFFNLYLSHFRLNGGRIAASLHSDILTIYIE
                     VGCIVFIIWMFWLFFVKPIRLTKKFGLKTG"
BASE COUNT          182 a           56 c          110 g          224 t
ORIGIN      
        1 tgcgatgggg gtttttttcc tttattacgt attttttgaa aataaaaata caaaaaaaca
       61 taagataaaa attatcgtat ctttaatttt aattttcatg ggattgaaga gaattgaact
      121 gttagcttta agtggtgcaa ttctagtgta ttatgtttta ttaaagtggg gaaaaaagat
      181 tcaaatccgt gcattagtgt gtactatttg tgcaactgtt atttcgttag tgtttattta
      241 cattatagat acaggaattt tggcattgct tatgtcaaat ttgggcatta cagatgacgg
      301 tgcaaggctt tcattttatc tatattcatc taaattttat gaacttggtt taggatatgt
      361 aggaacagga tggacatggt tttcaaaata cttttttaat ctttatttat cgcactttag
      421 gttaaatggt ggaagaattg cagcaagcct acacagtgat atattaacta tttatataga
      481 agttggatgt atagttttta ttatatggat gttttggtta ttttttgtga aaccgataag
      541 actaactaaa aaatttggat tgaaaacagg gg
//
LOCUS       DAMEEU010000206          554 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.220, whole genome shotgun sequence.
ACCESSION   DAMEEU010000206 DAMEEU010000000
VERSION     DAMEEU010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.220"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            168..362
                     /locus_tag="PB779_002961"
     CDS             168..362
                     /locus_tag="PB779_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740402.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
BASE COUNT          235 a           69 c           88 g          162 t
ORIGIN      
        1 taagaacaat agccttttat tatatatatt attcaaatta gttatatcga gtgaaaaaaa
       61 ctttcaaatt gattcttttt atttatcata aagatataga tacataatca ttttcactta
      121 catatatttg aatattaact aaaaacagca agaaagaaga ggatcaaatg tattatgtag
      181 aagtaaaaac aaaaggcgtc aaaaacaaac aatatgtgaa aggtatcagt aacgaatatc
      241 ctttacttgg ttcatggaaa gaagctgctc ctttttccaa accatgtgcc ataaaaataa
      301 agaacgagct agaaaaagaa ctgacttgtg gtaaagctgt tgtagatatc atcgaaaagt
      361 aaatccaatg tatagaaagg aagatcacac atgaaaagcg acgtacaaat tgctaagatt
      421 atagaattag aagaagaaga cgcagtgttg acaattgaaa aaaaataaat gtttgtatac
      481 catatgatta tttcaatatg tatcctggaa ttggagatct cgtagagcta tatcaagatg
      541 aatcaaatat actt
//
LOCUS       DAMEEU010000207          548 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.221, whole genome shotgun sequence.
ACCESSION   DAMEEU010000207 DAMEEU010000000
VERSION     DAMEEU010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.221"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            67..537
                     /locus_tag="PB779_002962"
     CDS             67..537
                     /locus_tag="PB779_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HDE0740403.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
BASE COUNT          200 a           99 c           82 g          167 t
ORIGIN      
        1 aaaacaaata gctagttttc agtttagcgc tctttttatt atataaaata gaaaggagaa
       61 aactttatgt ctatttataa ttttgaaact actttagaag acggcactgt ctattcattg
      121 aaaaaatatg caggcaaacc gataatcatt gttaacactg caacaaaatg cggtctagca
      181 cctcaattta aacaattaga agaactttac caagcttatc agacacaagg tctggttatc
      241 ttaggctttc cttccaatca atttaaacaa gagctagatt cagcgactga agcagcagaa
      301 gcttgtaaaa ccacttatgg cgttaccttc cctatgcatc aattgattga cgtaaatgga
      361 gaaaatacag atcctctttt tacttatctt aaaaatgaag ctcctggtac tgtcactaaa
      421 gcaataaaat ggaattttac taaatttttg attgatagaa atggcaaagt aatcgaacga
      481 tttgcaccac aaacttctcc attgaaaatg accgctgcaa ttgaatccgt tctttaactt
      541 aataaaaa
//
LOCUS       DAMEEU010000208          539 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.223, whole genome shotgun sequence.
ACCESSION   DAMEEU010000208 DAMEEU010000000
VERSION     DAMEEU010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..539
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.223"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            288..>539
                     /locus_tag="PB779_002963"
     CDS             288..>539
                     /locus_tag="PB779_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HDE0740404.1"
                     /translation="MAKITKNEQENLVENYTKKPAYSNSRLDAHFVCTSNPKLSFDAM
                     TIVGNLNKNSAKKLSDFMSLDPQIRLWDILQTKFKAKALQ"
BASE COUNT          210 a           79 c           86 g          164 t
ORIGIN      
        1 ataaattatc taaagagaat taagttttga ttatgtaata agttttggta ctaaaaaaga
       61 cttgatctaa ttagaccaag tcttttgtta gtgttatatt aataacaaaa taaaaataag
      121 aagtcgctca ctccccgacc aaagtttgtg agcaaaataa acagtcgatg tttgtttctt
      181 aattgtatat cttgatatta aacgatttaa gattattctt caagatatat attcgcaaat
      241 gtaattggaa aagcgacttc ttaaacaaaa ttaaggagtc gctttttatg gcaaaaataa
      301 cgaaaaatga gcaagaaaat ttggtggaaa attacacaaa aaaaccggcg tactctaata
      361 gccggttaga cgcacatttc gtgtgcactt ctaatccgaa attgagcttt gacgctatga
      421 cgatagtcgg aaaccttaat aaaaacagcg ctaaaaagct atccgatttt atgagtttag
      481 atccacaaat tagactttgg gatatacttc aaacaaaatt taaagctaaa gcactacaa
//
LOCUS       DAMEEU010000209          534 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.224, whole genome shotgun sequence.
ACCESSION   DAMEEU010000209 DAMEEU010000000
VERSION     DAMEEU010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 534)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 534)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.224"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>534
                     /locus_tag="PB779_002964"
     CDS             <1..>534
                     /locus_tag="PB779_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HDE0740405.1"
                     /translation="DGFKACTDPRQAAYAFERNYERPAATHPERQDYAVNWYNKFKDL
                     KPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSGYLGGCGMGAGTKYGLTHVIGNT
                     SAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINWARGGQVGSWFADGTYGHTGVIR
                     GLANGRMQTYEQNTELG"
BASE COUNT          163 a           80 c          137 g          154 t
ORIGIN      
        1 tgatggattt aaggcctgta ctgatccaag acaagcagca tatgcttttg aacgaaacta
       61 tgaacgtccg gcagcgacac atcctgaacg tcaagattat gcagttaact ggtataacaa
      121 atttaaagat ttaaaaccag gaggagctac tggagaagca ggactaaaac atttagagtc
      181 tttgattgga caacgaattg gcaatggtca gtgttatggc ttgtctgcag aatattcagg
      241 atatctgggt ggttgtggca tgggtgctgg aacaaaatat ggtttaactc atgtgatagg
      301 aaatacttct gcagcatctg atattggtat tgcctatgat tggtctgctg ttggttggaa
      361 agtgattcaa aaccctagat atgatcaatt agtagttggt gcaattatta attgggcaag
      421 aggtggacaa gtgggttcat ggtttgcaga tggaacttat ggacatactg gcgttatccg
      481 aggcttagct aatggtcgta tgcaaactta tgaacaaaac acagagttag gtat
//
LOCUS       DAMEEU010000210          531 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.225, whole genome shotgun sequence.
ACCESSION   DAMEEU010000210 DAMEEU010000000
VERSION     DAMEEU010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 531)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 531)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..531
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.225"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..291)
                     /gene="tnpB"
                     /locus_tag="PB779_002965"
     CDS             complement(<1..291)
                     /gene="tnpB"
                     /locus_tag="PB779_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HDE0740406.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWL"
     gene            complement(281..475)
                     /locus_tag="PB779_002966"
     CDS             complement(281..475)
                     /locus_tag="PB779_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740407.1"
                     /translation="MYKLNEIVPVQLGNEKSAPEKGKPAAAKLAMRIKRENGSEVLIY
                     NGINNYILQAILKELLSNAL"
BASE COUNT          155 a          112 c           92 g          172 t
ORIGIN      
        1 caaccatcga acctgttggt tcgttaaggt tcgaacttcg tctttcgtcc gaggccattt
       61 taacttgccg ttttctatcc gcttataaca gagaagaaaa ccatcaccgt cccaatagag
      121 aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa acggcatctt cgtaaagctc
      181 gagttgatac tcttgttgaa taagactggc aagaccatca attccttttc gcaaatctgt
      241 ttttccgcac acaatataaa tatgtttggt ttgaagtaaa tcataaagca ttggacaaca
      301 gttctttcaa aatagcttga agaatataat tgttaatacc gttatagatc aaaacttcag
      361 aaccattctc tcttttgatg cgcatcgcta acttggcagc cgcgggttta cctttttctg
      421 gtgcactctt ttcgtttcct aattggacag gaacaatctc atttaattta tacatagaaa
      481 acctccagac ttcttgatag ctcaagtata tcttgaggtg catttgttag t
//
LOCUS       DAMEEU010000211          518 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.227, whole genome shotgun sequence.
ACCESSION   DAMEEU010000211 DAMEEU010000000
VERSION     DAMEEU010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 518)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 518)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..518
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.227"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..>518
                     /locus_tag="PB779_002967"
     CDS             <1..>518
                     /locus_tag="PB779_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740408.1"
                     /translation="YISLLCKEEVRELPKSNSAVGIDLGIIDFAILSTGQKFDNNKFT
                     SKMEKKLKREQRKLSRRALLAKQKGINLFEARNYQTQKRKVARLHEKVMNQRTDFLNK
                     LSTEIIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSSFVSKLQYKADWYGRKIIKV
                     DKWFPSSQICSN"
BASE COUNT          192 a           80 c           90 g          156 t
ORIGIN      
        1 tatatttctt tgttatgcaa agaagaagtt cgcgaactac ctaaatctaa ttctgctgtt
       61 ggtattgacc taggtattat agactttgca attctttcta ccggtcaaaa atttgataat
      121 aataaattta cgtccaaaat ggaaaagaaa ctcaaacgtg aacaacgtaa gttgtcaaga
      181 cgtgccttat tagctaaaca aaaaggtatc aatctgtttg aagctagaaa ttatcaaaca
      241 caaaaacgta aagtagcacg attgcatgaa aaagtaatga atcaacgtac tgattttctg
      301 aataagttga gtacagaaat tatcaaaaat cacgatatca tctgtattga agacttaaac
      361 acaaaaggca tgttgcgtaa tcataaacta gcaaaaagta tttcggatgt ttcttggtct
      421 agttttgtgt ctaaattaca atacaaggct gactggtacg gtcggaaaat catcaaagta
      481 gataagtggt ttccatctag ccaaatctgt tcgaattg
//
LOCUS       DAMEEU010000212          513 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.228, whole genome shotgun sequence.
ACCESSION   DAMEEU010000212 DAMEEU010000000
VERSION     DAMEEU010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 513)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 513)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..513
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.228"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            17..>513
                     /locus_tag="PB779_002968"
     CDS             17..>513
                     /locus_tag="PB779_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HDE0740409.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDAT"
BASE COUNT          187 a           93 c           85 g          148 t
ORIGIN      
        1 aaaagaggac ttccctatga atgattttac tacagaaatt gtgcaaactc tagtcactaa
       61 aggcgattta aatgaattat tccgttcgca cttagaaaaa gcgataaaca cactcctacg
      121 gactgaatta acggcttttt tagattacga aaaatatgat cgcactggtt ttaattcagg
      181 taattcgaga aacggttctt actttcgatc aatcaaaacc gaatatggtg aattaacatt
      241 ggaaatacct agagatcgta atggtgagtt taaacaacaa actttaccag cctacaaaag
      301 aacaaacgat acattggaaa ccactattat ccatttattc gaaaaaggtg ttacgatgtc
      361 tgaaattgct gatttgatcg aaaaaatgta cggtcatcac tatactccac aaaccatgtc
      421 caacatgact aaagttctga ctgaagaagt aaatgccttt aaatccagag ccttaaatga
      481 taagtatgtc gctattttta tggacgctac tta
//
LOCUS       DAMEEU010000213          502 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.230, whole genome shotgun sequence.
ACCESSION   DAMEEU010000213 DAMEEU010000000
VERSION     DAMEEU010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 502)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.230"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..168)
                     /locus_tag="PB779_002969"
     CDS             complement(<1..168)
                     /locus_tag="PB779_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HDE0740410.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSIS"
     gene            complement(187..348)
                     /locus_tag="PB779_002970"
     CDS             complement(187..348)
                     /locus_tag="PB779_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002608889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HDE0740411.1"
                     /translation="MQDKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPV
                     DAISYGVRK"
     gene            418..>502
                     /locus_tag="PB779_002971"
     CDS             418..>502
                     /locus_tag="PB779_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740412.1"
                     /translation="MPRRQRRTYSKEFKQQIVDLYLAGKPCA"
BASE COUNT          171 a           97 c           60 g          174 t
ORIGIN      
        1 tgatattgaa gaattagaac tttcatataa agccttttct atttcattgc ttgatttcat
       61 tattgttaaa caagaataca agcaagaaag aactatagtt aatatgataa aaattattaa
      121 agttctattt ttctttcttg taatatatgc tatagcattt tttatcactt tcctaactac
      181 tcctttctat tttcttactc cataactaat tgcatccact ggacaagcat ttttacatcg
      241 tccacatctg atacactcca gatgattgca attctcaact gaatctttat tcatttggca
      301 aactttttta cattttccac aattaataca cttatcctta tcctgaatcg gctacactag
      361 actagacaga aaaaataagg tgtgtagaat aataaaaaac acactggagg atttttcatg
      421 ccaagacgtc aacgaagaac ctattcaaaa gaattcaaac aacaaatcgt cgatctctat
      481 ctcgctggta agccttgcgc ag
//
LOCUS       DAMEEU010000214          498 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.231, whole genome shotgun sequence.
ACCESSION   DAMEEU010000214 DAMEEU010000000
VERSION     DAMEEU010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.231"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
BASE COUNT          169 a           91 c           69 g          169 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttcc
//
LOCUS       DAMEEU010000215          486 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.232, whole genome shotgun sequence.
ACCESSION   DAMEEU010000215 DAMEEU010000000
VERSION     DAMEEU010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 486)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 486)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..486
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.232"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            55..486
                     /locus_tag="PB779_002972"
                     /pseudo
     CDS             55..486
                     /locus_tag="PB779_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          198 a           80 c           93 g          115 t
ORIGIN      
        1 gacagaaaaa ttaaggtgtg tagactagaa gaaaacatac caggaggaat ttttatgtct
       61 aagagaacac gaagaacttt ttcacaagaa ttcaagcaac aaatcgtcaa tctttactta
      121 gctggaaagc cacgtgtaga aatcattcga gaatatgaac taacggcttc agcatttgac
      181 aaatgggtaa agcaatctaa aacgagtggt tcattcaaag aaaaagataa tcttacgcct
      241 gaacaaaaag aattgttaga actacgtaaa agaaaccagc aattagaaat ggaaaatgat
      301 attttaaagc aagcagcgct gatattcgga cgaagagaca agtaatcgat gcgaataagc
      361 atctttaccc tatatcagcg atgtgcagaa tattaggtct atcacgtcag tcctattatt
      421 atcaatcaaa accaaagaaa gacgaatcag aacttgaaga agtagtcgct gaagaattta
      481 tccgca
//
LOCUS       DAMEEU010000216          462 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.235, whole genome shotgun sequence.
ACCESSION   DAMEEU010000216 DAMEEU010000000
VERSION     DAMEEU010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.235"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..430)
                     /locus_tag="PB779_002973"
     CDS             complement(<1..430)
                     /locus_tag="PB779_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HDE0740413.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRA"
BASE COUNT          132 a           92 c           59 g          179 t
ORIGIN      
        1 ctgctcttaa acgaataact tcttcttcaa gagactcatc tttaagtttt ttaggaatgt
       61 ttagcttgga attcatacta atttttctgc cccttttttg gctctcaagt gaagaagcac
      121 cgccttcttc atattgctct atccatttac ttagagttct atttgaaccg atattaaatt
      181 ttttagcagt ttcttggata gaaagaccat ttgtttccat atattctata acatcaagtt
      241 taaattttgt agtgtagctt ttgccacctc caaccaagcc ttcccaacca tgatagttat
      301 aaatccttac ccaatgtcta accagtgtac gatttatttg atatttatgt gcaagatatt
      361 tgtagccgcc ttcgttattt aaatagtctg aaactacttt tttcttaaaa acaaatgtat
      421 atttccgcaa aaaaagcacc ccttttaatt agatttctag tc
//
LOCUS       DAMEEU010000217          460 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.236, whole genome shotgun sequence.
ACCESSION   DAMEEU010000217 DAMEEU010000000
VERSION     DAMEEU010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 460)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 460)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..460
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.236"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(20..91)
                     /locus_tag="PB779_002974"
     tRNA            complement(20..91)
                     /locus_tag="PB779_002974"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56..58),aa:Glu,seq:ttc)
     gene            complement(113..200)
                     /locus_tag="PB779_002975"
     tRNA            complement(113..200)
                     /locus_tag="PB779_002975"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(164..166),aa:Ser,seq:gct)
     gene            complement(225..298)
                     /locus_tag="PB779_002976"
     tRNA            complement(225..298)
                     /locus_tag="PB779_002976"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(262..264),aa:Ile,seq:gat)
     gene            complement(312..382)
                     /locus_tag="PB779_002977"
     tRNA            complement(312..382)
                     /locus_tag="PB779_002977"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(348..350),aa:Gly,seq:tcc)
     gene            complement(384..459)
                     /locus_tag="PB779_002978"
     tRNA            complement(384..459)
                     /locus_tag="PB779_002978"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(424..426),aa:Asp,seq:gtc)
BASE COUNT          132 a          128 c          108 g           92 t
ORIGIN      
        1 taaaactata ttaaattaat gacccgtacg ggattcgaac ccgtgttacc gccgtgaaag
       61 ggcggtgtct taaccgcttg accaacgggc caggtaaaac aaaatattga aacggagaag
      121 gagggatttg aaccctcgcg ccggtttccc gacctacacc cttagcaggg gcgcctcttc
      181 agccacttga gtacttcccc aaaaccaata agattttgta ctaatgggcc taaatggact
      241 cgaaccatcg acctcacgct tatcaggcgt gcgctctaac cagctgagct ataggcccat
      301 aaaaaactaa aagcgggtga cgagaatcga actcgcgaca acagcttgga aggctgtggt
      361 tttaccacta aactacaccc gcatggcggt tccgacggga atcgaacccg cgatctcctg
      421 cgtgacaggc aggcatgtta acccctacac cacggaacca
//
LOCUS       DAMEEU010000218          449 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.238, whole genome shotgun sequence.
ACCESSION   DAMEEU010000218 DAMEEU010000000
VERSION     DAMEEU010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..449
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.238"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(34..270)
                     /locus_tag="PB779_002979"
                     /pseudo
     CDS             complement(34..270)
                     /locus_tag="PB779_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          146 a           76 c           77 g          150 t
ORIGIN      
        1 agaaggactg accttctgtc tcagattttt ttgttatttc acttgaatca attgattgat
       61 caaaaaaatc ctgattttca tgttctcaaa tgatttaaat ccataagata atcgtttcag
      121 tgtcttgata tggggaatct tggcctctat tttgccatta gaatacgggt aaatcatagc
      181 attgtaaata ccttcttcat acgttaaaag gttttgaagt ttcgtgcgaa gttgtgcatc
      241 aagtgtttca ggaagatttt ttaataacgc cgtttgtata attaagcgag acaaataaaa
      301 aagccattta tgttacactc caattgtaat acccgctaaa gcatacaagg agagtgaaca
      361 taaatgactt atacccatct tacaccaaac gagcttgtaa tgatagaagc atattttcat
      421 caagaaactc cggttgctat cgttgcgaa
//
LOCUS       DAMEEU010000219          421 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.243, whole genome shotgun sequence.
ACCESSION   DAMEEU010000219 DAMEEU010000000
VERSION     DAMEEU010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..421
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.243"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            53..385
                     /locus_tag="PB779_002980"
     CDS             53..385
                     /locus_tag="PB779_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740414.1"
                     /translation="MRKITMQSGLCERRIEKLTKKNSGNSMKKKKKKLLKQFAGIGNA
                     NVKFICLSCGEKESIPMDVVKFLDDADIANDPNNPPQFTCEKCGKEMYPEYYRNALGI
                     EFKISDVQ"
BASE COUNT          164 a           57 c           95 g          105 t
ORIGIN      
        1 tatgaattcg ttgggatgag tgtgcgcaaa aatggacggt tagttattaa atatgcgaaa
       61 gataaccatg caaagcggtt tatgcgagag gagaatcgaa aaattgacca aaaagaattc
      121 aggcaacagt atgaagaaga aaaagaaaaa acttttaaag caattcgctg ggattgggaa
      181 cgccaacgtg aaatttatat gtctaagttg tggtgaaaaa gaatcaatcc caatggatgt
      241 agtaaaattt ttagatgatg cagatattgc aaatgatccg aacaatcctc cccaatttac
      301 ctgtgaaaaa tgtgggaagg agatgtatcc agaatattat agaaacgccc ttggaataga
      361 gtttaagatc agtgatgttc aataagaagg ttaatcatac aaaaagtcca ccggagaatt
      421 c
//
LOCUS       DAMEEU010000220          408 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.246, whole genome shotgun sequence.
ACCESSION   DAMEEU010000220 DAMEEU010000000
VERSION     DAMEEU010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 408)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 408)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..408
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.246"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..390
                     /locus_tag="PB779_002981"
     CDS             <1..390
                     /locus_tag="PB779_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HDE0740415.1"
                     /translation="KDRKEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSL
                     IENQDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFD
                     TYNQKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          158 a           73 c           64 g          113 t
ORIGIN      
        1 aaagaccgaa aagaaatctg tgatgacttt aaggctgttt atcaagctaa ctcaaaagaa
       61 gaagcgaata ccttcttatc cggcatgatt gagaaatgga agaaaaacta tcctaaagtg
      121 acgcagtcac tcatagaaaa ccaagactta ttaacttttt atgattttcc acctagcatt
      181 cgtagaacca tttactcaac caatctaatc gagtctttca ataagcaaat taaaagatac
      241 agccgtagaa aagagcagtt tcaaaatgaa gaatcactag aacgctttct agtcagcatt
      301 tttgatacat acaatcaaaa atttctaaac agaagccata aaggttttca acaggtaacc
      361 gatacattag tttcaatgtt tactgagtaa ctaattattt tgcaggag
//
LOCUS       DAMEEU010000221          375 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.255, whole genome shotgun sequence.
ACCESSION   DAMEEU010000221 DAMEEU010000000
VERSION     DAMEEU010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 375)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.255"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(<1..132)
                     /locus_tag="PB779_002982"
     CDS             complement(<1..132)
                     /locus_tag="PB779_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HDE0740416.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          132 a           69 c           76 g           98 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaat
//
LOCUS       DAMEEU010000222          370 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.denovo.259, whole genome shotgun sequence.
ACCESSION   DAMEEU010000222 DAMEEU010000000
VERSION     DAMEEU010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..370
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.denovo.259"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            82..>370
                     /locus_tag="PB779_002983"
     CDS             82..>370
                     /locus_tag="PB779_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HDE0740417.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCR"
BASE COUNT          132 a           59 c           76 g          103 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa
//
LOCUS       DAMEEU010000223        40245 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.019, whole genome shotgun sequence.
ACCESSION   DAMEEU010000223 DAMEEU010000000
VERSION     DAMEEU010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 40245)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40245)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40245
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.019"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            complement(39..1439)
                     /locus_tag="PB779_002984"
     CDS             complement(39..1439)
                     /locus_tag="PB779_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HDE0740418.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            1657..3318
                     /locus_tag="PB779_002985"
     CDS             1657..3318
                     /locus_tag="PB779_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HDE0740419.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            3275..3973
                     /locus_tag="PB779_002986"
     CDS             3275..3973
                     /locus_tag="PB779_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HDE0740420.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            3989..5413
                     /gene="araA"
                     /locus_tag="PB779_002987"
     CDS             3989..5413
                     /gene="araA"
                     /locus_tag="PB779_002987"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HDE0740421.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            5720..6880
                     /locus_tag="PB779_002988"
     CDS             5720..6880
                     /locus_tag="PB779_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-3-phosphoglycerate dehydrogenase"
                     /protein_id="HDE0740422.1"
                     /translation="MYHVHLIDAIPEQEIEKLQGEYFKIIDDLPAEGIVIRSTKVKDE
                     WLTPDLLAISRAGVGVNTINVEKASENGTIVMNTPGVNANAVKELVLCCLLLSSRPII
                     EASRMVQTLTGPNILEQAENKRSAYVGRELQGKTIGLLGLGAIGTKVALSCYSLGMDV
                     LGYSIRDAQLDYVRQADLETVLSTSDYIVVMLPLTEDTKGLIDQANIEKMKKDAVLIN
                     VGRSEIVDKYAVMQALEKQHLAKYLTDFPEEEFLENDRILMLPHLGGSTQEALADSGR
                     LAVEALKDYLLFGTVREAVNYPSARMFFQAPFRFTIFYQKKTNILAEIFSLLNENELA
                     IADISRNHKNEHVYILIDIDSTDFEQLNQVKQQLEKISGVRKVRLLKKPERP"
     gene            6998..8857
                     /locus_tag="PB779_002989"
     CDS             6998..8857
                     /locus_tag="PB779_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HDE0740423.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            8967..9449
                     /locus_tag="PB779_002990"
     CDS             8967..9449
                     /locus_tag="PB779_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740424.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLYPENFRLSLKAPEIRAFRRI
                     "
     gene            9645..9833
                     /locus_tag="PB779_002991"
                     /pseudo
     CDS             9645..9833
                     /locus_tag="PB779_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604486.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            9879..10844
                     /locus_tag="PB779_002992"
     CDS             9879..10844
                     /locus_tag="PB779_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740425.1"
                     /translation="MAVFRVEKNKGYTVMSNHHLRNKNLTLKAKGLLSQMLSLPEDWD
                     YTLKGLSYINRESIDAIRTAVWELEKAGYIRREQGRDAKGKMADMVYTIYEQPVLENP
                     VLENPTSDNPVLENPTSDNPASENPTQLNKEVQRTDLSKKEKIITDGQSTHSIPIPSP
                     TPAPMEGEAAATPPERKRTGKDEAVRIYREIILENIEYAYLIQDRSIDREQLDEIVDL
                     MLETVCTARKTIRVAGDDYPAELVKSKYMKLTGEHIRFVLDCLRENTTKVRNIKQYLR
                     AMLFNAPSTISNYYTALVAHDMAQPDWGKPKSGLPDYSCGEGESL"
     gene            10866..11078
                     /locus_tag="PB779_002993"
     CDS             10866..11078
                     /locus_tag="PB779_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HDE0740426.1"
                     /translation="MKQGALIFDERTDRYDIRFDLADYYGGLHCGECFDVMIGGKWRP
                     TRIEMAENWYLVGIRADDLSGLRVRI"
     gene            11153..11629
                     /locus_tag="PB779_002994"
     CDS             11153..11629
                     /locus_tag="PB779_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002569165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PcfB family protein"
                     /protein_id="HDE0740427.1"
                     /translation="MQEEVTQKTIALSMKTGKLTAQVLQAALKKYLQHRAKGKNTLHH
                     GQQSLKQLKKHGADLSNIEITEANIGAFKPCAKKYGVDFTLRKDKTTQPPHYVVIFKA
                     KDADNLDLAFREFTAKTLSKEQRPSIRKVLSAVKQKAAAQTKQRAKEKIKERGLEL"
     gene            11626..13434
                     /locus_tag="PB779_002995"
     CDS             11626..13434
                     /locus_tag="PB779_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HDE0740428.1"
                     /translation="MKPDVKKLLILNLPYLIFVYLFAKCGEAYRLAAGADLSGKLLHF
                     ADGFAAAFANPLPSLHLFDLCIGIAGAVIVRLVVYCKSKNVKKYRKGMEYGSARWGTA
                     KDIAPYIDPKFENNILLTQTERLTMTGRPKDPKTARNKNVLVIGGSGSGKTRFFVKPN
                     LMQCFPTTDYPTSFVVTDPKGTLVLETGRMFQQAGYRIKILNTINFSKSMKYNPFVYI
                     HSEKDVLKLVNTLISNTKGEGEKSAEDFWVKSERLFYSALIGYIWYEAPAEEMNFSTL
                     LEMINASEAREDDPEFQSPVDLMFERLEQKDPDHFAVRQYKKFLLSAGKTRSSILISC
                     GARLAPFDIREVRELMEDDEMELDTIGDEKTVLYLIMSDTDTTFNFILAMLQSQLINL
                     LCDRADDVYGGRLPVHVRLILDEFANIGQIPNFDKLIATIRSREISASIILQSQSQLK
                     AIYKDAAEIISDNCDSVLFLSGRGKNAKEISDALGKETIDSFNTSENRGSQTSHGLNY
                     QKLGKELMSQDEIAVMDGGKCILQLRGVRPFLSEKFDITKHPRYKYLADADKKNTFDV
                     DRFLTITRRKRQQVVTQDEVFDLYEIDLSDEDAAAE"
     gene            13511..13726
                     /locus_tag="PB779_002996"
     CDS             13511..13726
                     /locus_tag="PB779_002996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016147847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Maff2 family protein"
                     /protein_id="HDE0740429.1"
                     /translation="MAFFNSAVTTLQTIVIGLGGALCVWGGINLLEGYGQDNPGAKSQ
                     GVKQLVAGGGVALIGVTLVPLLSGLLG"
     gene            13818..14681
                     /locus_tag="PB779_002997"
     CDS             13818..14681
                     /locus_tag="PB779_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740430.1"
                     /translation="MISEIIEEWIKGILMDGITGNLSGLFDTVNAKVGEIAADVGRTP
                     QAWNSGIFNMLHSLSETVIVPIAGAILALVMCYELIQMITEKNNMHDFDSSMFFRWIF
                     KSAFAILIVTNTWNIVMGVFDATQSVVNQSAGVIIGQTSIDFNTLIPDLESQLEAMSV
                     GALLGLWFQTLVVGLTMNILSICIFLVTYGRMVEIYVVTSLGPIPLATMGNAEWRGMG
                     QGYLKSLLALGFQAFLIMVVVGIYAVLIQNIGSASDISGAIWGCMGYTVLLCFCLFKT
                     GSISKAVFGAH"
     gene            14718..15254
                     /locus_tag="PB779_002998"
     CDS             14718..15254
                     /locus_tag="PB779_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002604480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methyltransferase"
                     /protein_id="HDE0740431.1"
                     /translation="MSTYNIIYADPPWRYDCKNVQGAAENHYSTMSIDELCALPVERL
                     ASKDCLLFLWATFPMLPEALRLIKAWGFSFKTVAFVWLKQNRKSLTWFYGLGRWTRGN
                     AEICLLATHGKPKRRSASVHQFIISPIEQHSKKPDVTREKIVELAGDLPRVELFARQK
                     TPGWDVWGNEVECDLILT"
     gene            15268..15690
                     /locus_tag="PB779_002999"
     CDS             15268..15690
                     /locus_tag="PB779_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDE0740432.1"
                     /translation="MAYVTVPKDLTHVKSKVVFGLTKRQLICFSGALVIGVPLYFLTR
                     DYLTNSAAALLMVFAMLPGFLLAMYERHGQPLEVVIMQIIQCCFIQPKERPYQTDNTY
                     TALVRQYQMEQEVKAIVQKGNPKRNRKNKADPRPAKRN"
     gene            15620..18019
                     /locus_tag="PB779_003000"
     CDS             15620..18019
                     /locus_tag="PB779_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HDE0740433.1"
                     /translation="MSKKEIPRETEKTKLTRAQRKEIDAVIRKYKGDGRPHTAQQSIP
                     YEVMYPDGVCRVSPGVFSKCIEFADISYQLAQPDTQTAIFEKLCDLYNYVDASIHIQF
                     SFLNRKVDPVQYAKSFEIAPQGDDFDDIRAEYTGILQKQLANGNNGMVKTKYLTFTIE
                     AESVKAARARLKRIGFDLLGYFKSMGAVAHVMDGWERLNLLHGVYHPDGEIFNFDWKW
                     LAPSGLSTKDFIAPSSLCFGNAKTFGMGGKYGAVSFLQILSPELSDDMLADFLNTESG
                     VLVNLHVQAIEQTKAIKTIKRKITDLDAMKIAEQKKAVRSGYDMDILPSDLATYGEDA
                     KKLLTKLQTRNERLFQLTFLVLNVADTKQKLNNDVFQAAGVAQKHNCPLVRLDYQQEQ
                     GLASSLPLGVNQIKIQRSLTTSSVAVFVPFVTQELFQGGAAMYYGINAKSRNMIMLDR
                     KQARCPNALKLGTPGSGKSMSCKSEIVSVFLTTPDDIFISDPEAEYYPLVKRLHGQVI
                     RLSPTSKDFVNPLDINLNYSEDDNPLALKSDFVLSFCELVMGGKNGLEAIEKTVIDRA
                     VRVIYRPYLADPRPENMPILSDLHKALLDQHVPEADRVAQALDLYVSGSLNVFNHRTN
                     VDIGNRLVSFDIKELGKQLKKLGMLIVQDQIWGRVTANRSQGKATWYFADEFHLLLKE
                     EQTAAYSAEIWKRFRKWGGIPTGATQNVKDLLSSPEIENILENSDFITLLNQASGDRK
                     ILAERLNLSTEQQKYIDNSEPGEGLLIFENVVLPFTNPIPHNTQLYKIMTTRLNEVAG
                     V"
     gene            18051..20042
                     /locus_tag="PB779_003001"
     CDS             18051..20042
                     /locus_tag="PB779_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HDE0740434.1"
                     /translation="MKELKAKAKVTQAMTRDGLTLENQATGEVENISSREAEQDLSAP
                     GPGGTADKLLERADAIHDGHKAKKAAKQAGAVAAEGDAALHRPSARLQLSEEERADPD
                     LQPYIRKSDKRADKLDKARAAIPKKRVPVKETVFDEASGKAKTVLHFDKQDKGPPSLK
                     PNPAGRPVSEVFLFGHGKIHEVEHENVGVEGGHKGEELAERQAGKAIRSTIRHHRLKP
                     YWDAEKAERRLLSANAEYFYQKSLRDNPEIAQAASNPISRFWQKQQIKRQYAKAARTA
                     GQTAGAAAQGAAKTAGASTKAAKAAAKESERAASFVARHWKGALAVLVLGLLMLLIIG
                     GLQSCTAMFGSAGSGITASSYFSEDSDMLAAEDAYAELEAELQDYLDNYEATHDYDEY
                     HFDLDEISHDPYVLISILSALHDGIFTIGEVQGDLSMLFDKQYILTENVVVETRYRTE
                     TDTWTDAEGNTHTDTYQVPYDYYICYVTLENFDLSHVPVYIMDEETLSFYSLYMSTLG
                     NRPDLFSGSQYPNASTLTPPTYYDVPPEALEDATFAAMLKEAEKYIGYPYVWGGSSPS
                     TSFDCSGFISWVINHSGWNVGRLGAQGLYNICTPVSSSQAKPGDLVFFKGTYDTPGVS
                     HVGLYVGNNVMLHCGNPISYTNLTSNYWQSHFYSYGRLP"
     gene            20065..20316
                     /locus_tag="PB779_003002"
     CDS             20065..20316
                     /locus_tag="PB779_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4315 family protein"
                     /protein_id="HDE0740435.1"
                     /translation="MATKLDRIEKDIQKTKSKIAEFQKQLRELETQKTEQENLQIIQL
                     VRGMNMKPEEFAAFLRSGAMQAAPAATPYHEQEDNAHEE"
     gene            20306..21535
                     /locus_tag="PB779_003003"
     CDS             20306..21535
                     /locus_tag="PB779_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4366 domain-containing protein"
                     /protein_id="HDE0740436.1"
                     /translation="MKNKTRRISRILPALLAVMLCVTAFPVTALAGGNDPAPAPLPEA
                     TTEPATGGLEPETDETGTATDGTETEAEKDTGPLTGKDITDLFSALFGSKVSIAATDD
                     GIQITTGTDKKEPEQTGTVTTNGGRLNVRTGAGLDKTAFTQLPNGTTVEVVGTDGDWI
                     KILLPERIGYVHSDYMTVSEKEVAATGEGGFSLSIDPEEIASLLELFNGGGASAALSP
                     DGNLSLIDDIGSAAKNGKQFITVETKNGNVFYLIIDRDDEGKETVHFLNQVDEADLLT
                     LMEDGETVTPAAVCSCTTKCKAGAVNTNCPVCKTNLTECSGPEPQEPQPEEPEAPEEE
                     PKGGAGGLIVFLLVALAGGGAALYYFKFKKPKAETTGSDDLGEYDFGEDEDLEDEEPE
                     TEFDPEADFVSEQEDEE"
     gene            21532..23613
                     /locus_tag="PB779_003004"
     CDS             21532..23613
                     /locus_tag="PB779_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase 3"
                     /protein_id="HDE0740437.1"
                     /translation="MTYKLVIAEKPSVARSIAGVIGATEKHDGYLEGNGYLVSWCIGH
                     LVSFADAGRYDERFKKWRYEDLPILPETWQYIVPDDKKQQFDVLCSLMQRPDVTGLVC
                     ATDAGREGELIFRFVYQMAGCQKPFERLWISSMEDSAIKDGFAHLKPGGDYDPLYQSA
                     LCRAKADWLIGINATRLFSVLYHKNLTVGRVQTPTLKMLVDRDAKITDFKKEKYHIVH
                     ITAGGADAVSSRFSDAAEANTVKAACAKAQAVCVSVTREKKTEQPPKLYDLTTLQREA
                     NRLFGYTAKQTLDYAQALYLKKLLTYPRTDSQYLTDDMLPAVESLVSGLWELVPFAKG
                     LNLSPQFDRILNSKKVSDHHAIIPTAEFVKQGFGTLAESEKKLLSLICCKLLCAVAGP
                     HIYEAVTATFTCAGQEFTAKGKTVLSPGWKEIERRFRSSLKTDADEDAEAVRELPELC
                     EGQTFADVAASVTEHFTTPPKPYTEDTLLSAMERAGAEDMPEDAERKGLGTPATRAAI
                     LEKLVQMGFVQRKGKQLIPTKDGINLAVVLPEALTSPQLTAEWENRLTEIAKGQADPD
                     EFMDGIETQARELVQTYSCISEEKQKLFQAERVPIGTCPRCGEAVYEGKKNYYCGNRA
                     CQFVMWKNDRFFEERKKAFTPKIAAALLKTGKVKVKGLYSVKTGKTYDGTVLLADTGG
                     KYVNYRIEHRS"
     gene            23762..27682
                     /locus_tag="PB779_003005"
     CDS             23762..27682
                     /locus_tag="PB779_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002418674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4316 domain-containing protein"
                     /protein_id="HDE0740438.1"
                     /translation="MNEVFSIQVHNRQFLEQGKQGVWLDLPTTTETLQAALRDVGITA
                     DNPQDFFINGYSCPEDRHLAIPYDMVLAADVDELNFLAARLGQLDAAEIAELNAALQN
                     PRGGFENIGQIIDYTENVDYYVHLPDVRGDGQLGDYYLNRSGMVDMPEEWKAGIDTAQ
                     FGRHIAQQEQGVFTQYGYLVRSGDEWQRVHEGQPVPEEYRVMHYPQPEADREEPQAQQ
                     PEASESPDKAPPPVIPIMLDGMNSKERMKVITDRLETGVQELFESSRYMAYLSAMSKM
                     HDYSLNNTLLIAMQGGSIVAGYNRWQDEFDRHVKRGEKGIKILAPAPFKVKQQMEKID
                     PATQQPVIGADGKPVTEEQEVTVPAFKVVTVFDISQTEGKDFPMPYISELTGDVQQYQ
                     DFFAALERTSPYPISIEPISDGAKGRCFYAKQRIAINEGMSELQTLKTAIHEIAHAKL
                     HAIDREAPAEEQAARPDRSTREVQAESVAYTVCQYYGLDTSDYSFGYVADWSSGRELS
                     ELKASLETIRATASELITEIDGHFAQLQQEREARQEQEAVTVDVTPEAAAPAQAEEEQ
                     APALDPAAEPLVTVLWSESPQLKDGQQMPLHEADALFARLDAAYPAEAGYDKTAFRID
                     CIFQGEPDSYEGRQDFGDRDGSLIEHIQSYHQFYAQDENWKKHVIATTGIEGWEQDKA
                     HRDMLLGEFVPYMKLHCSLAQMEQTAQGRLQSGETLTPEETAYLGALLSYVQECRPML
                     NQGQYQLPEPPKLADFDQSLQDYKAQVQAEIAQEAAAAGMTVEEYAAAGYEAPQQDTF
                     SIYQLRGGEETRDYRFEPYERLQAAGLAVDSANYDLVYTAPLDKSTSLEDIYRTFNID
                     HPADFRGHSLSVSDVVVLHQNGQDTAHYVDSFGYMEVPEFLRENPLRTAELSTEQNEN
                     MIDGIINNTPPEPQPEEPEQLSFEDVAVASGQTQEEPPEAAPPQTAVRYYPINEGAAR
                     RAKEAMSFSDYRPGSATAEYRHYVDQAVEIAERQKKRVEPEYHEKIDSLLDTYARKLA
                     ENMNKGYEITARVPSVLIAGPSNFPVRAKEKQNAASDRNMEEFQYIQGLLDKIRSTGM
                     GGISADDPQAVSKLEKKLEKLEASQELMKAVNAYYRKHGTLDGCPHLTERGIENLKAD
                     MASGWHYEKKPFQSWQLSNNNAEIRRLKGRIEELTRQKEAAYVGWEFDGGTVEINRVA
                     NRLQIFFEGKPDAAVRDELKSNGFRWSPKAGAWQRQLNDTTIRVADRIKCIQPLSGEK
                     PSALQLAARREKEKPSIRAQLNAAKTEQAKQPPAREKSKGLEVE"
     gene            27683..28627
                     /locus_tag="PB779_003006"
     CDS             27683..28627
                     /locus_tag="PB779_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002417119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740439.1"
                     /translation="MQKFENVDVLAALEQIMRQNTAFYQSDFGIDKDIIRRDAASDQA
                     ADKTLLWMSRPSGTYCFRERDVFLKDTRQYNTWKFYGEQTRDKILAYAVELTGTQGGT
                     IRGNLYELDYPQHFRHVIETAQPVSVNRLFYEHGTRDIPESQRFDGSPDRVLGNFLYY
                     EAQPHDPAVLQEALRTEQHSRGRAVPGDFKVHVTALHDSRIETEARRIVDSLKDLSAP
                     NSPNKTHFMVEISPHFAAIASTKDNDRLFAMLPYKSLCFTGMKGRHGVYAVINRDERR
                     DVSIRRPRPSIRKQLSDSKQAASPKKAAARTKKNELEV"
     gene            28631..28834
                     /locus_tag="PB779_003007"
     CDS             28631..28834
                     /locus_tag="PB779_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposon-transfer assisting family protein"
                     /protein_id="HDE0740440.1"
                     /translation="MMHFTVEEENLICMYHNADRRRTINRLTAVMPVMDGDMRAQAQQ
                     TLSKLERMTDADYDGQKFHFTDE"
     gene            complement(29134..29370)
                     /locus_tag="PB779_003008"
     CDS             complement(29134..29370)
                     /locus_tag="PB779_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740441.1"
                     /translation="MDGQEKLLDYETIKAAVAGERWATEKVLAHYADYINELSTVEIR
                     QANGKKKKVIDEDIRQRISLKLLEALPSFPLEQR"
     gene            complement(29553..29939)
                     /locus_tag="PB779_003009"
     CDS             complement(29553..29939)
                     /locus_tag="PB779_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich VLP domain-containing protein"
                     /protein_id="HDE0740442.1"
                     /translation="MDARAMSIPRMNYPQYRKARKLTHECCNYCDGNCLLLDDGEECI
                     CVQSISYSLLCRWFKAAVLPLDAALYAEITKDRDEVKRCCECGATFTPKSNRAKYCAA
                     CSKRMRRRKEAERQRKRYWKPTHLEL"
     gene            complement(29921..31249)
                     /locus_tag="PB779_003010"
     CDS             complement(29921..31249)
                     /locus_tag="PB779_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HDE0740443.1"
                     /translation="MAVTKIHPIKSTLKKALDYIENPDKTDGKLLVASFACSYETADI
                     EFEMLLAQAYQKGNNLGHHLIQSFAPGEATPEQAHEIGKQLAEEVLQGKYPYVLTTHI
                     DKGHVHNHIIFCAVDMVNQRKYISNKQSYAYIRRTSDRLCKENGLSVVKPGQSKGKSY
                     AEWDAQRKGTSWKAKLKAAIDAAIPQAKDFDDFLRLMQAQGYEIKPGKFISFRAPGQE
                     RFTRCKTLGEAYTEEAIKERIKGRVITRAPKERKGISLRIDLENNIKAQQSAGYERWA
                     KLHNLKQAAKTLNFLTEHGIDTYPDLESKVAEITAASDEAAATLKAMEHRLADMAVLI
                     KNISTYKQLWPVAMEYRNAADKAKFRREHESTLILYEAAAKALKGQGVKKLPDLYALK
                     AEYKRLAEEKERLYEKYGEAKKQMQEYGIIKQNVDGILRMTPGKEWTQEL"
     gene            complement(31210..31539)
                     /gene="mobC"
                     /locus_tag="PB779_003011"
     CDS             complement(31210..31539)
                     /gene="mobC"
                     /locus_tag="PB779_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HDE0740444.1"
                     /translation="MANRKRKIVLRVPVTPEERAMIEQKMALLHTKNFSAYARKMLID
                     GYIVNMDTSDIRAQTAEIQKIGVNVNQIAKRLNGMGPVYAQDIEDIKGALAQIWQLQR
                     YILSSQR"
     gene            complement(31797..32168)
                     /locus_tag="PB779_003012"
     CDS             complement(31797..32168)
                     /locus_tag="PB779_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HDE0740445.1"
                     /translation="MANIEDCPGFETFGADVKAARQAKRVSRKAMAEKINIDWRYLAN
                     IENDGAIPSLPVVIQLIKACGLPVERYFNPEIMREESELRQRVSHKLKLCPEEYLPII
                     EGAIDSAILIEKPKKNETEDV"
     gene            32313..32498
                     /locus_tag="PB779_003013"
     CDS             32313..32498
                     /locus_tag="PB779_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HDE0740446.1"
                     /translation="MDYMTLKEAGEKWGVPPRWINYYCAAGRIPGAVKMATIWLIPKT
                     AEKPIDRRTKKGKAVTE"
     gene            32656..32823
                     /locus_tag="PB779_003014"
     CDS             32656..32823
                     /locus_tag="PB779_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740447.1"
                     /translation="MKKRNFIMTEMENARNKDEEAAAVSAVYGRIEKAGIWILYGEVS
                     RHWITAGLMRL"
     gene            33441..34100
                     /gene="vanR"
                     /locus_tag="PB779_003015"
     CDS             33441..34100
                     /gene="vanR"
                     /locus_tag="PB779_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance response
                     regulator transcription factor VanR"
                     /protein_id="HDE0740448.1"
                     /translation="MSIRILLVEDDDHICNTVRAFLAEAGYQVDACTDGNEAYTKFYE
                     NTYQLVILDIMLPGMNGHELLREFRAKNDTPILMMTALSDDENQIRAFDAEADDYVTK
                     PFKMQILLKRVEALLRRSGALAKEIRVGRLTLLPEDFTVLCDGTELPLTRKEFEILLL
                     LVQNKGRTLTHEIILSRIWGYDFEGDGSTVHTHIKNLRAKLPENIIKTIRGVGYRLEE
                     S"
     gene            34103..35446
                     /gene="vanS"
                     /locus_tag="PB779_003016"
     CDS             34103..35446
                     /gene="vanS"
                     /locus_tag="PB779_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012579101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanB-type vancomycin resistance histidine kinase
                     VanS"
                     /protein_id="HDE0740449.1"
                     /translation="MERKGIFIKVFSYTIIVLLLLVGVTATLFAQQFVSYFRVMELQQ
                     TVKSYQPLVELIQNSDRLDIQEVAGLFHYNNQSFEFYIEDKEGSVLYATPNANTSNSF
                     RPDFLYVVHRDDNISIVAQSKAGVGLLYQGLTIRGIVMIAIMVVFSLLCAYIFARQMT
                     TPIKALADSANKMANLKDVPPPLERKDELGALAHDMHSMYVRLKETIARLEDEIAREH
                     ELEETQRYFFAAASHELKTPIAATSVLLEGMLENIGDYKDHSKYLRECIKMMDRQGKI
                     ISEILELVSLNDGRIVPIAEPLDIGRTVAELLPDFQTLAEANNQRFVTDIPAGQIVLS
                     DPRLLQKALSNVILNAVQNTPQGGEVRIWSEPGAEKCRLFVLNMGVHIDDTALPRLFT
                     PFYRIDQARSRKSGRSGLGLAIVQKTLDAMSLQYALENTSDGVLFWLDLPLTSTL"
     gene            35617..36423
                     /locus_tag="PB779_003017"
     CDS             35617..36423
                     /locus_tag="PB779_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala carboxypeptidase VanY-B"
                     /protein_id="HDE0740450.1"
                     /translation="MEKSNYHSNADHHKRHMKQSVEKRAFLCAFIISFTVCTLFLGWR
                     LASVLEATQIPPIPATHTGSSTDVVENLEENALATAKEQGDEQEWSLILVNRQNPIPA
                     QYDVELEQLSNGERIDIRISPYLQDLFDAARTDGVYPIVASGYRTTEKQQEIMDEKIA
                     EYKAKGYTSAQAKAEAETWVAVPGTSEHQLGLAVDINADGIHSTGNEVYRWLDENSYR
                     FGFIRRYPPDKTEITGVSNEPWHYRYVGIEAATEMYNQGVCLEEYLKPEK"
     gene            36441..37268
                     /gene="vanW"
                     /locus_tag="PB779_003018"
     CDS             36441..37268
                     /gene="vanW"
                     /locus_tag="PB779_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010815683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycopeptide resistance accessory protein
                     VanW-B"
                     /protein_id="HDE0740451.1"
                     /translation="MDRKRLTQRFPFLLPMRRAQRKMCFYAGMRFDGCRYAQTIGEKS
                     LSHLLFETDCALYNHNTGFDMIYQENKVFNLKLAAKTLNGLLIRPGETFSFWWLVRHA
                     DKDTPYKDGLTVTNGKLTTMSGGGMCQMSNLLFWMFLHTPLTIIQRRGHEVKEFPEPN
                     SDEIKGVDATISEGWIDLKVRNDTDCTYQIWVTLDDEKIIGQVSADKEPQALYKITNG
                     SIQYVRESGGIYEYAQVKRMQVALGTGEIIDCKLLYTNKCKICYPLPESVDIQEENQ"
     gene            37265..38236
                     /locus_tag="PB779_003019"
     CDS             37265..38236
                     /locus_tag="PB779_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase VanH-B"
                     /protein_id="HDE0740452.1"
                     /translation="MRKSVGITVFGCEQDEANAFRALSPDFHIIPTLISDAISADNAK
                     LAAGNQCVSVGHKSEVSEATILALRKVGVKYISTRSIGCDHIDTTAAERMGISVGTVA
                     YSPDSVADYALMLMLMAIRGAKPTMHAVAQQDFRLDRIRGKELGDMTVGVIGTGHIGQ
                     AVVKRLRGFGCHVLAYDNSRKMDADYVQLDELLKNSDIVTLHVPLCADTRHLIGQKQI
                     GEMKQGAFLINTGRGALVDTGALVEALESGKLGGAALDVLEGEDQFVYTDCSQKVLDH
                     PFLSQLLRMPNVIITPHTAYYTERVLQDTTEKTIRNCLNFERSLQHE"
     gene            38229..39257
                     /gene="vanB"
                     /locus_tag="PB779_003020"
     CDS             38229..39257
                     /gene="vanB"
                     /locus_tag="PB779_003020"
                     /EC_number="6.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--(R)-lactate ligase VanB"
                     /protein_id="HDE0740453.1"
                     /translation="MNRIKVAIIFGGCSEEHDVSVKSAIEIAANIDTEKFDPHYIGIT
                     KNGVWKLCKKPCTEWEADSLPAILSPDRKTHGLLVMKESEYETRRIDVAFPVLHGKCG
                     EDGAIQGLFVLSGIPYVGCDIQSSAVCMDKSLAYILTKNAGIAVPEFQMIDKGDKPEA
                     GALTYPVFVKPARSGSSFGVTKVNGTEELNAAIEAAGQYDGKILIEQAISGCEVGCAV
                     MGNEDDLIVGEVDQIRLSHGIFRIHQENEPEKGSENAMITVPADIPVEERNRVQETAK
                     KVYRVLGCRGLARVDLFLQEDGGIVLNEVNTLPGFTSYSRYLRMVAAAGITLPALIDS
                     LITLALKR"
     gene            39263..39871
                     /locus_tag="PB779_003021"
     CDS             39263..39871
                     /locus_tag="PB779_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-Ala-D-Ala dipeptidase VanX-B"
                     /protein_id="HDE0740454.1"
                     /translation="MENGFLFLDEMLHGVRWDAKYATWDNFTGKPVDGYEVNRIIGTK
                     AVAFALREAQIHAAALGYGLLLWDGYRPRTAVDCFLRWAAQPEDNLTKEKFYPNIERA
                     ELITKGYVASQSSHSRGSAIDLTLYHLDTGELVSMGSNFDFMDERSHHTAKGIGDAEA
                     QNRRCLRKIMESSGFQSYRFEWWHYKLIDEPYPDTYFNFAVS"
     gene            complement(39937..40110)
                     /locus_tag="PB779_003022"
     CDS             complement(39937..40110)
                     /locus_tag="PB779_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740455.1"
                     /translation="MLPEKNGGLDFSKPPPAKYKMGVGKVCPTAVFFFSAAGQIEYYN
                     LQCITKDALTTFQ"
BASE COUNT        10912 a         9646 c        10470 g         9217 t
ORIGIN      
        1 cttatttctt gaagctgacc acttctgtca caacctcttt aagaatgatg gatagaaata
       61 cgtttaggat aagttttttt agatgcactt tgttcgattt cctctaaaga tttcccacga
      121 gtttctggta cgatctcttg aataaataaa acccctaaaa agcagatgat cccaaaaatg
      181 ccgaaaacga tttcttgaga catagaagca gtcatcacag gaaaaagcaa gccaactagg
      241 aaagaaccaa tccaattaaa agaagaggct aggccagatg ctcgcccgcg gacagctagt
      301 gggaatattt cgcctacgat tacccatgtc agtggagccc atgtgcaaga ataaaatgcg
      361 acataaatac ataaaaacaa gagaatcaac aacgaatttg tatgagcatc cagtacagtt
      421 cctaaaacag ctggtaggat gaaagaaagt cccatcacgc taccgcctat tttcaataaa
      481 gttcgccgat tgaacttgtc tgcaataacc aaaaagagca aagaaccagc aactaaaatg
      541 attccttgga tgatcggcca catcaatgca tcgctcgctg catgcccagt cgctttttct
      601 acgatcagcg gaatatagta aaaaatagca ttagctcctt gaaattgctg gaatactgct
      661 acaccaatac cggcaatgac taaggaacga tatttttcta aaaacaaagt atgccaagaa
      721 gttccggttg tcttttcttg tttgacattc agctggattt gttcgaattc ctgttcagct
      781 tcttttggtg tccgaatata gttcaatact ctttttgcct cttccaagcg gccagattgc
      841 ataagaaaac gcggtgactc tggtagagct aaaacaccga aaaataaaat cagcgcgggg
      901 acagcagcga gccctaacat cacgcgccaa gccatcgttt caggcaaccc ttttagcaaa
      961 taatctgcaa cataggaaag gagcatgcca gaagcaatca tcacttgatt gatccctgac
     1021 aatcttcccc ttagtctagc aggagccatt tcagacatat aagcaggaac tagggcagat
     1081 gcagcgccaa cagctaaacc tagaagaatc cttgctgcaa tcagaaaata agaaccattg
     1141 tgaggggcag atgcagaaag gacagaacca gccataaaaa taagtgcaga aagaagaatc
     1201 atttttcgtc gtccaagctt atcagaaaga agaccagata aagagccgcc aaggatcgca
     1261 cctaacatga ccgaagacgt gatccatcct atcaaagaag ctttacctgc caaaccccaa
     1321 tcatgctgta aaaaaggtaa ggcgccggtc ataacaccaa tatcatatcc aaatagaatg
     1381 ccgccaaatg cgccaaaaaa ataaataaac gatgaggaaa cttttttttc ttttttcata
     1441 agtattctct ccttctagaa tttcgagaag gcggttgatc agattttgta agcaatttca
     1501 ttttataact tatgtacgta caaaacaagt gttttttatt gtattcttgt aaataactgc
     1561 ttgacatgta cgtacaaaag tatacaataa tcattgtaag cgctactaaa aagacggttt
     1621 gatcaggttt gacgagaagg agggagttaa atcattatga aggaagtaaa tgcgcaaagt
     1681 atgttagatg tcatagatgg tcgtacatct ttagggattg agtttggatc aactaggatc
     1741 aaagctgtat tgattgattc atcttttact cctattgccg ctggtagtta tgagtgggaa
     1801 aacaaactag aaaatggtat ctggacctat tcattagaag atatttggaa aggactgcgc
     1861 gtcagttacc gaaaaatggc agcagaagta ttcgaaatct atggcgagaa tcttacgaca
     1921 atcgggtcga ttgggttcag tgcaatgatg cacggttatc tagcatttga tagcaaggaa
     1981 cagttactag taccatttcg tacttggcga aatacaatca ctgaagaagc agaacgaata
     2041 ttaacggaaa aatttcaata caatattccg cagagatgga gtatcgctca tttgtatcaa
     2101 tctattttga ataaagaaga acatgtgaaa gaaattaatt ttttgacaac gcttgcaggt
     2161 tatgtccatt ggcagcttac tggtgagaaa gtactaggcg taggagatgc atcaggcatg
     2221 tttcctatcg atccttcaac gaaaacctac catcaagaaa tgaaaaatat ttttggtcag
     2281 ttaatcgaaa aagcgcacgt agcgattgac ttggatcaca ttttgcctaa agttctagta
     2341 gcaggagaag aagctggcaa gttaagcgaa tcaggggctt atctgatcga ccctacggga
     2401 aatttgagac caggaatccc ggtttgtccg ccagaagggg atgcaggaac cggtatggtc
     2461 gctacgaaca gtgtagccaa agggacaggg aacatttcgg ctggtacttc cgccttcgct
     2521 atgatcgtat tagaaaaaga actagaaaat gtccatccgg aaatcgacat ggtcactaca
     2581 ccttcaggag aactagtagg catggttcat acgaataact gctcttcgga tatcaatgct
     2641 tgggtcagta tttttgaaga atttaccaat tctttgggta tggagataag cagagataaa
     2701 ttattcacgg tattattcaa caaagcgcta gaaggcgata cggattgcgg gggattactt
     2761 tcttatggtt atttttccgg tgaaaacatt acaggagtaa atgaaggaag gccattattt
     2821 gtacgtacac caggtagccg ttttgattta gcgaatttca tgcggatcca tttagccagt
     2881 gcttttggtg caatgagaat cggaatggat atattgaaat ctgagaatgt ccaaattgat
     2941 cgtttagtgg ggcatggggg gatttttaaa acaccagaag ttggacagcg gattctagca
     3001 tctgctatgg aggcaccagt tacagtgatg gacacagccg gagaaggtgg agcgtgggga
     3061 atcgcgttat tagcagccta tatgatggat cgacatggga agtctttaga aaacttcttg
     3121 gcagaagacg tgtttggaca agaccaagga atcaccatca caccttcagc agaagaaata
     3181 gcaggctatc agatatttat gagacgttac cgtgagggga tcgacattga aaaaacagcg
     3241 attcatcaat tgcaagaaaa aggagtgata gaaaatgctg gaacaactga aagaagaagt
     3301 ataccaagca aatcttgact tgcctaaaca cggactcgtc aaatatacat ggggaaatgt
     3361 gagcgctttt gatcctgaaa cacgatattt cgttatcaaa cctagcggag tcagttatga
     3421 agagatgaca gcagacgaca tggtcgttgt ggacttggac aatcatatca ttgaaggtaa
     3481 actcaatccc tcttcggata cgcctactca tgctgtttta tatcgttcat ttcctcaaat
     3541 cggaggaatc gtccatactc actcgacatg ggcgacgatc tgggcacaag caggattgga
     3601 tgttcctgcg atggggacga cgcatgcaga tactttttat ggatcggtac cttgtgctcg
     3661 atttttgaca caacaggaaa tcgacagcgg gtacgaatat gaaacaggaa aagttatcat
     3721 agaaacattc aaagaacgca aaattgatcc cttagcaatt ccaggggtac ttttacacgg
     3781 acacggtcca tttacttggg ggaaagatgc gcaaagtgcg gtaatgaacg cagtcgtact
     3841 agatgaagta tgcaagatga atttatttac cagacagctc aattcatttt cagaagagct
     3901 gcctcaacgg attttagata aacattattt acgaaaacac ggaaaaaatg cgtattacgg
     3961 acaaaacaaa taaaaggagt ggctaattat gttgaatatt ggagaaaaag aattttggtt
     4021 tgttgtagga tcacagcatt tatatgggga agaagcactg cgagaagtaa agaaacatgc
     4081 acaagaaatg gtcgatgaac tgaatgaaaa tggccaattg ccttatccaa tccgccttca
     4141 agaattagca gttactgctg atacgatcac aaaaatcatg aaagaggtca attatcgaga
     4201 agaagtagca ggtgtgatca cttggatgca tactttctca ccagcaaaaa tgtggatccg
     4261 cgggacaaag cttctacaaa aaccattgct tcatttagct acgcaatata acgaaagcat
     4321 tccttggaaa acgatcgata tggatttcat gaatttaaat caatccgctc atggtgaccg
     4381 cgaatatggg ttcatcaatg ctcgattaaa taaacaaaat aaaatcgtcg ttggctactg
     4441 gaaacgacct gagatccaaa aagagattgc tgattggatg gatgttgcag tagcctataa
     4501 tgaaagtttt ggaataaaag tggctcgttt tggtgacaac atgagaaacg tgggtgtcac
     4561 agaaggagac aaagtggaag cacagattca atttggttgg actgttgatt attttggtat
     4621 cggagatctt gtacaagtaa tcgatcgcgt atcagacgaa gaagtcgatc aattatttga
     4681 agagtacaag gaattgtata ccttcgacta tggtgattat gaagaaaaga catgggagga
     4741 acatgtaaaa gtacaagctc agcaggaaat cggtattcgc cgtttcttag aagaaggagg
     4801 ctataacgct tttacgacta attttgaaga cctgtatgga atgaaacaac tacctggact
     4861 agctgtacaa cgtttgatgg cagaaggata cggttttgct ggggaaggcg actggaaaac
     4921 tgcagcgatt gatcggttgc tgaaaatcat ggctcgaggg aaagatacag gattcatgga
     4981 agattatact tacgagctag ctagtggcca agaagcaatc ttggaatccc atatgatgga
     5041 agtagatccg acgcttgctg cgacgaaacc aagaatcgtt gtttctcctt tatcaatggg
     5101 agatagagaa gatccggcgc gtcttgtatt tgatgggaaa gcaggagaag gggtagtcgt
     5161 atcgatggca gatttcggta cgcattataa actgctgatc aatgaagtag aagcctttga
     5221 accaacgact gaagcaccta atttacctgt tgcacgtgtg ttatggaaaa ctaaaccgaa
     5281 tttccatgaa ggtgtccatt catggattca ggcaggtggc ggtcatcata ccgttgtctc
     5341 gctaaatcta acaacagatc aaattgaaac gtgggcaaaa ttagttgagt tggaaacagt
     5401 ggttattaga taaaaagagg ttgtgaaaaa gccacttagt tttaagaaat aagaagagat
     5461 tgacgaaatt tgcttttcaa cttttttgaa atttagtctt attatcaatg tcagctaacg
     5521 gaacaccatt tatcaagata tctcaccctc aatattttgc tctcgaaaat aaggcttatg
     5581 gcagtaactt gtcatagcct tatttttatc actcagccta ctctgctcta actgctcttt
     5641 ttgcttctag gaagtcaaat ggtaaacagt tgtctaattg cagaaatttc gagatacttg
     5701 ttagtaagga gggggtttta tgtatcacgt tcatttgatt gatgctattc cagaacaaga
     5761 gatagaaaag ttacaagggg aatatttcaa aataatagat gatttgccag ccgaaggaat
     5821 agttattcgt agtacgaaag tgaaagatga atggcttaca ccagatttgc tagcaatttc
     5881 aagagctggt gttggggtga acacgatcaa cgttgaaaaa gcttctgaaa acgggacgat
     5941 cgtcatgaat acaccaggtg taaatgctaa tgcagtaaaa gagcttgttt tgtgctgttt
     6001 gctcttatct tcccgtccga taatcgaagc aagtcgtatg gtacaaacac taacaggtcc
     6061 taatatttta gaacaggcag aaaacaaaag aagtgcttat gtgggacgag aattgcaagg
     6121 caaaaccatc ggtcttcttg gtcttggagc gataggcaca aaagtagcgc taagttgcta
     6181 tagcttaggg atggatgtct tgggttattc tatccgcgat gcccagttgg attatgttcg
     6241 gcaagcagat ttagaaacag ttctttctac ctcggattac atcgtagtca tgctgccgtt
     6301 gacagaagat acaaaaggat tgatcgatca ggcgaatata gaaaaaatga aaaaagatgc
     6361 tgtacttatc aatgtaggaa gaagtgaaat tgttgataaa tatgctgtta tgcaagcatt
     6421 ggaaaaacaa catctggcta aatacttgac tgattttcca gaagaagagt tcttagaaaa
     6481 tgaccgtata cttatgttgc ctcatctagg gggatcgact caggaagctt tggcagacag
     6541 cggacgtttg gcagttgaag ccttaaaaga ttatcttttg ttcggtacgg ttagagaagc
     6601 ggtcaattat ccatccgcac gaatgttttt ccaagcgccg tttcgattca ctatatttta
     6661 tcaaaagaaa accaatatat tagcagagat attttctctg ctgaatgaga acgagctagc
     6721 gatcgcagat atatcgcgta accataagaa tgagcatgtc tacatattga ttgacataga
     6781 cagtactgat tttgaacagc tcaatcaagt gaaacaacag ctagaaaaaa tttctggagt
     6841 acgaaaggtc cgcttattaa agaaaccaga aaggccataa agaaagagaa tatttggatt
     6901 tcattaattc ttctttccgt tctttacttt cgaatttcgt acaactaaaa taagagaagc
     6961 aacattcttt tattgataga aatgaaggag caagcatttg aaaagatata taagcagact
     7021 ttcgaccaaa cagaaaaaga ttttaaaagg aacagcagca atcatcagta tcttttttct
     7081 tgttgttttt agtaatttat ttttgcagtg gtgtcaaaat gatctatccg tagaccttgc
     7141 gttgaaattt gctttttctt ggcatacgga aaaattcttc ttagcctgtc tcgtcttgct
     7201 gattattctt atttttctga ttgcactagc aggatctgtc cctttaggtt cccttacgta
     7261 tgtcgtagcc atcggtgtat taggttttgc aaattatatg aaaatgagtt atcggcaaga
     7321 accgatttat ccagacgatt tgaagatgat cactgaaatc ggattgctga aagatatgac
     7381 cggcactatg ctgtttacag tgatcttagc tgccgcagga accgtgatag gattgttttg
     7441 ctggtacatg tttcgaagcc tgaaaaaagg aaggcgattc caattgatcc gattaacgac
     7501 actgcttgtg gcaattggac tgctagggta tatcagtaat ttcaacaatc ccgataattt
     7561 gttgcgaaaa gcatataata aaacggcact atggatacct tacagccaga aaatgaacta
     7621 ctataacact ggttttatcg gtgggttttt gtacaatctg aaggtagaac caatggatga
     7681 acctgaagga tattcgaaag aaaagatcaa agaaatcact gaaaaatacc agaagctagc
     7741 cgatgaaaaa aataaaactg tagaggaaga gtcgccgaac atcgtgttcg tgatgagtga
     7801 aagtttctca gatcctagtc gattaaacgg cgtagaagta tctggtgagc cattggcaga
     7861 ttattatgaa gtagctgatc aaacatatag tggcaatatg ctttctcaaa actatggcgg
     7921 tggaacagca aatatcgaat ttgaagcatt gactggtttt tctatggcgt tatttaatgc
     7981 gcaactcacc accccttaca cgatgcttgt accaaaaatg gatcagcttc cttctatcgt
     8041 ttcagcgtta aacgcacaat cataccagac gacagcgatc catccataca atacttcgat
     8101 gtataaaaga gaggatgttt atcagacatt aggatttgac cagttcatca gcgagcgtac
     8161 gatgacctat acggatacga tagagaataa tccatatatt tctgatgagt cagcttacaa
     8221 agaagtaatg acacttctca aggaagaaaa aacacctcag ttcattcatt tagtcacgat
     8281 gcagacacat atgccctacg atggaaagta tgataatcta gactatcctg caaaaacttc
     8341 agatggaagt gggacacttg acttagagaa ttatctgcaa gatatttcct atagcagcac
     8401 ggcactgaag cagttcacgg aagaattgaa gaatctttct agaaggactt tagttgtttt
     8461 ttggggggat catcttccag ggatctattc agatacgatc caagcaaaaa atgacaaaca
     8521 aacattgcat gaaacacaat ttcttatgtt cgacagtaaa ggagaattag aaaagcaaac
     8581 gactcacgat gcaatcacca gtccgtttta ttttgcagcg aatctaatgg aacagacgaa
     8641 tcagacaaca aatggctttt atcagctgct tttatcatta gaacaggaac ttccggcgtt
     8701 tgaacgagaa ctgtactatc aaaacggaca gtggtataaa gaagcgcaat tcaatcgctc
     8761 gcaacaagag atttacgacg aatatcaatt gatccaatat gacattgtcg cagggaaaca
     8821 atatagttta gcagatggtt tctttgagca cgaataagaa tggcgagctg tatagaaacc
     8881 attaaatttt ttcaagtact tgtcatttga ggataaaaac aagtagaata aataataaca
     8941 acaatggaga aagtaggaaa acgaacatgt taccgaatat tggctattat gtgcagtcca
     9001 tcgatcaaat cgtcaaggaa acagaagcaa tcggagaagg aatgcatccg aaatatgaag
     9061 tgatcagaaa cgcaattgat gaaggaaaaa caagtgaact ggacaaatcg actcttgaag
     9121 agatcatcct gttatttgaa gaaggaacaa aaaaatatcg ggcaatgctt atgaaagtca
     9181 gtactttgcg tccaccagca aaagcaatgg gcattcataa aaattttgaa aaagcttatc
     9241 tttcatatgt agcaggctgt gaagaaatga tccaaagtat cgatcttgaa tcaggggtag
     9301 atgaagatct attcaataca tctgaagcaa aacaagacca agcgacagac caattgacag
     9361 ctgccatcca aaaaatgact aatttgtatc cagaaaattt taggttatcg ctgaaagccc
     9421 cggaaatacg ggcatttcgc aggatatgag aactcaattt actaccaatt tactactttc
     9481 ggattgagcc gcatatatgc tgaaccatac tgctaatacc cgccacccca aatacggcac
     9541 atcataaatt gaatacgaca ccgtaaacgc ggcgttcctc tttcccgtca tgggagaaca
     9601 ggacgccgct tttttatgcc caaatagaga aaggaggcga cgccatgcta tttacttccg
     9661 gccctgaccg ggcgtttgaa cggctgatgc aggaaaagcc cggtttcgat cactacgacg
     9721 gcggcggggc ggacgcgccg gaggattgcg gcacctgccg attttaccgc ccggattgga
     9781 aatatcaatt ctgccagttt gcagagtgtc cctatcagcc gggcaagctg accgactatg
     9841 cagcggtcaa attcacagtg aaaggagcga acaacgctat ggcagttttc cgtgtggaaa
     9901 agaacaaagg ctatacggtg atgtcaaatc accacctgcg gaataagaac ctgaccttaa
     9961 aggccaaggg cctgctgtcg cagatgttgt ccttgccgga ggattgggac tataccctaa
    10021 aaggactgtc ctatatcaac cgggaaagca tcgacgcgat caggacagcg gtatgggagc
    10081 ttgaaaaagc tggatatatc cggcgtgagc agggccgtga cgcaaaaggc aaaatggccg
    10141 atatggtcta taccatctac gaacagccgg tattggaaaa cccggtattg gaaaatccaa
    10201 catcggataa cccggtgttg gaaaatccga catcggataa tccggcgtcg gaaaatccaa
    10261 cgcaattaaa taaagaagta caaagaactg acttatcaaa aaaagaaaaa ataattacag
    10321 atggacaaag tacccattcc attcctatcc catccccgac ccctgcccct atggagggcg
    10381 aggcagcggc tacgccgccg gaacggaaaa ggacaggaaa ggatgaggct gtacggattt
    10441 atcgggaaat cattttggag aacatcgagt atgcctatct cattcaggac aggagcattg
    10501 accgtgaaca gcttgacgaa atcgtagacc tgatgctgga aaccgtctgc accgcccgaa
    10561 agacaatccg tgtcgccggg gacgactacc ctgccgagct ggtgaaatcc aagtacatga
    10621 agctgaccgg cgaacatatc cgctttgtcc ttgactgtct gcgggagaac acaacgaaag
    10681 tccgcaatat caaacaatac ctgcgggcta tgctgttcaa cgcccccagc accatttcca
    10741 actactacac ggcccttgtc gcgcacgaca tggcacagcc cgattgggga aagcctaaat
    10801 ccggcctgcc ggactattcc tgcggcgagg gcgaaagcct gtaacgagaa aaggaggacg
    10861 accctatgaa gcagggcgca ttgatttttg acgagcgaac agaccgttac gacatccgct
    10921 ttgatctggc cgactattac ggcggcctgc attgcgggga gtgtttcgac gtgatgatcg
    10981 gcggcaaatg gaggcccacc cgcattgaaa tggccgaaaa ctggtatctt gtcggcatcc
    11041 gggccgacga cctttccggc ctgcgggtgc ggatttgacc tatatctacc tgcggcgtct
    11101 ggtggttccg ccttagacgc cgcttttgac tttctgacaa ggagggatgc gattgcagga
    11161 agaagttact caaaagacca ttgccctgtc catgaaaacg ggcaagctca cggctcaagt
    11221 gctgcaagcg gcgctgaaaa agtacctgca acaccgggcc aagggcaaaa acacgctgca
    11281 ccacggccag cagagcctaa agcagcttaa aaagcatggg gctgatctct ccaacattga
    11341 gatcaccgag gccaacattg gagcgttcaa gccatgcgcc aagaaatacg gcgtggattt
    11401 taccttacga aaagataaga ccacccagcc gccccactac gttgtgattt tcaaggccaa
    11461 ggatgcagat aaccttgatc tggcgtttcg ggagtttacc gccaagacgc tttccaagga
    11521 gcagcggccc tctatccgca aggttttgtc cgctgtgaag caaaaggcgg cggcccagac
    11581 caagcagcgg gccaaggaga aaatcaagga aagggggctg gaactgtgaa gcctgacgta
    11641 aagaaattgc tgatcctgaa cctcccgtat ctgatttttg tgtacctgtt tgcgaaatgc
    11701 ggggaggcgt accggctggc cgctggtgct gacctgtcgg ggaagctcct gcattttgcg
    11761 gatggttttg cggcggcttt tgccaacccg ctgccaagcc tgcacctgtt tgacctgtgt
    11821 atcggtatcg ccggtgccgt gatcgtgcgg ctggtggtgt actgcaagag caagaacgtg
    11881 aagaaatacc gcaaaggcat ggagtatggc agcgcccgct gggggacggc caaagacata
    11941 gcgccttaca tcgaccccaa gtttgaaaat aatatcctgc tcacccaaac ggaacggctt
    12001 accatgaccg gcaggcccaa agaccccaag acagcgcgga ataaaaacgt gctggtgatc
    12061 ggtggcagcg gttcagggaa aacgagattt ttcgtgaaac ccaacctgat gcaatgcttt
    12121 ccgaccacgg actatccgac ttcgtttgtg gtgacagatc cgaaaggcac tttggttctg
    12181 gaaaccggca ggatgttcca gcaggcgggc taccgcatta aaatcctgaa taccattaac
    12241 ttttccaagt ccatgaagta caaccccttt gtctacatcc attcggaaaa ggacgtgcta
    12301 aagctggtaa ataccctgat ttccaacacc aagggcgagg gggaaaagtc agcggaggat
    12361 ttttgggtga agtcggaacg gttgttttat tcggccctga tcggctatat ctggtacgag
    12421 gccccagcgg aggaaatgaa cttctcaacg ctgctggaaa tgataaacgc cagtgaagcc
    12481 cgcgaggacg acccggagtt tcaaagcccc gtcgatctca tgtttgagcg tttggagcag
    12541 aaagaccccg accattttgc ggtgcgccag tacaagaaat tcctgctgtc cgcaggcaag
    12601 acccgttctt ccatcctgat ttcatgcggt gccagacttg cgccctttga catccgggag
    12661 gtacgcgagc tgatggagga cgacgaaatg gagctggaca ccatcgggga cgaaaagacg
    12721 gtgctgtatc tcattatgag cgatacggac acgaccttta atttcattct ggctatgctc
    12781 caaagccagc taatcaacct gctttgtgac cgggctgatg atgtgtacgg cgggcggctg
    12841 cctgtccatg tacgcctgat tttggatgaa tttgccaaca ttggccaaat acccaatttc
    12901 gataaactca ttgccaccat tcgaagccgt gaaatatcgg cctctattat tttgcagagc
    12961 cagtcgcagc taaaagcgat ttacaaggac gccgccgaga tcatttcgga taactgcgat
    13021 agtgtgcttt tccttagtgg gcgcggcaaa aatgccaagg agatttccga tgcgctgggg
    13081 aaagaaacga ttgacagttt caacaccagc gagaaccggg gaagccaaac gtcccacgga
    13141 ttgaactatc aaaaattagg aaaggagttg atgtcccaag acgaaattgc cgtgatggac
    13201 ggcggcaagt gtatcttgca gctacggggt gtgcgcccgt ttttatcgga gaaattcgat
    13261 attaccaagc atccccggta caaatacctt gccgacgccg acaagaagaa tacctttgac
    13321 gtggacagat ttttgactat cacgcgccgg aaacggcagc aagtggtaac gcaggatgaa
    13381 gtattcgacc tgtatgaaat cgacctgtcg gacgaggacg ccgccgctga ataaacagcg
    13441 gcttttttca ttccaacaac aaaatcaaaa aatcattatg agccggaaac cggcagaaag
    13501 aggtaaattt atggcatttt ttaattccgc agttactact ttgcagacta tcgtgatcgg
    13561 actgggcggc gctctgtgcg tatggggcgg catcaatctg ttggagggat acgggcagga
    13621 caatccgggg gcaaaatcgc agggtgtcaa gcagcttgtc gctggcggcg gcgtggccct
    13681 gatcggtgtc actctggttc ccctgctgtc cgggctgctg ggctgatcct ggcctttgtc
    13741 cctgtccaaa cccttaacta atcgcctccg cgtcctcccg gccagaccgg gagggcgcgg
    13801 gaaaggaggt gctacccgtg attagtgaaa tcattgaaga atggataaaa ggcatcctca
    13861 tggacggtat cacgggcaac ctgtccgggc tgttcgatac ggtaaatgcc aaagtcggag
    13921 aaatcgccgc cgacgtggga cgaaccccgc aggcatggaa cagcggtatt ttcaatatgc
    13981 tgcacagcct gtcggaaacc gtgatcgtcc ccatagccgg ggccatactc gcccttgtca
    14041 tgtgctatga gcttatccag atgataacgg aaaagaacaa tatgcacgac tttgacagct
    14101 ccatgttctt ccgctggata ttcaaatccg cgtttgcaat cctgatcgta acgaacacat
    14161 ggaacatcgt catgggcgta ttcgacgcca cccaaagcgt cgtcaatcaa agcgccggtg
    14221 tgattatcgg gcagacatcc attgatttta acaccctgat accagacctt gaaagccaat
    14281 tggaggctat gagcgtgggc gctcttttgg ggctgtggtt ccaaaccctt gttgtgggcc
    14341 tcaccatgaa tatcctttcc atctgcattt tccttgtgac ctatggccgc atggtggaaa
    14401 tctatgttgt cacgtcgctg gggcctatcc cccttgccac aatgggcaac gcggaatggc
    14461 gcggcatggg ccaagggtat ctgaaatccc tgctggcgct gggcttccaa gcctttttaa
    14521 tcatggttgt ggtgggtatc tacgcggtgc tgatacagaa tatcggttcc gcttccgaca
    14581 tatccggcgc aatctggggc tgtatgggct atacggtgct gctgtgcttc tgcctgttca
    14641 agaccggcag tatatcaaag gccgtattcg gggcgcattg atcccaaaat ccaagcatac
    14701 acaggaggaa cttgtttatt tcaacgtaca acatcattta cgctgacccg ccgtggcggt
    14761 atgactgcaa aaacgtacag ggcgcagcgg aaaatcacta ttccaccatg agcattgacg
    14821 agctgtgcgc cctgccggtg gaacggctgg cgtccaaaga ctgcctgctg tttttgtggg
    14881 ccacattccc catgctgccg gaagctctgc ggttaatcaa agcgtggggc ttttcattca
    14941 agaccgtggc ttttgtatgg ctgaaacaga accgtaaaag ccttacatgg ttttacgggc
    15001 tgggccgctg gacaagggga aacgcggaaa tctgcctgct ggcaacacac ggcaagccga
    15061 agcgtcgttc tgcctctgtc catcagttta ttatcagccc gattgaacaa cacagcaaaa
    15121 agccggatgt gacccgtgaa aaaatcgtag agctggcggg cgatttgccc cgcgtggagc
    15181 tgtttgccag acagaaaacc cccggctggg acgtgtgggg gaacgaggtg gaatgtgacc
    15241 ttatcctgac gtgaaaggag gtgccaaatg gcttatgtaa ccgtccccaa ggacttaacc
    15301 catgtgaaaa gcaaggttgt gtttgggctt accaaacggc aactgatctg tttttccggg
    15361 gcgctggtga tcggcgtccc cttatatttt ctcacccgtg actatcttac caacagcgcg
    15421 gcggccctgc tcatggtatt tgccatgctg ccgggctttt tgcttgccat gtacgagcgt
    15481 cacggccagc cccttgaagt ggtgattatg cagatcatcc agtgctgctt catccagcca
    15541 aaggagcgtc cctatcagac cgacaacacc tacaccgccc ttgtgcggca ataccagatg
    15601 gaacaggagg taaaggccat tgtccaaaaa ggaaatccca agagaaaccg aaaaaacaaa
    15661 gctgacccgc gcccagcgaa aagaaattga cgcggtaatc cgtaaatata agggcgacgg
    15721 caggccccac acggcgcagc agagcatccc ctacgaggtc atgtacccgg acggcgtgtg
    15781 ccgggtatcg cccggcgtct tttccaagtg cattgagttt gcggacatca gctatcagct
    15841 tgcccagccg gacacgcaga cggctatctt tgaaaaactg tgcgacctgt ataactatgt
    15901 ggacgcctcc attcatatcc agttttcttt cctcaatcgg aaagttgacc cggtgcagta
    15961 cgccaagagc tttgagatcg cgccgcaggg ggacgacttc gacgacatcc gggccgagta
    16021 caccggcatt ctgcaaaagc agcttgcaaa cggcaacaac ggcatggtaa agaccaaata
    16081 cctgacattc accatcgagg ccgaaagcgt gaaagcggcg cgagccagat tgaagcgcat
    16141 cggctttgac ctgttaggct atttcaagag catgggggcc gtagcccatg tgatggacgg
    16201 ctgggaacgg ctgaacctgc tgcatggcgt gtaccacccg gacggcgaga tattcaattt
    16261 tgactggaag tggctggccc cgtccggcct ctccaccaag gattttattg ccccgtcctc
    16321 cctgtgcttc ggcaatgcaa agacattcgg catgggcggc aaatacggcg cggtaagttt
    16381 cctgcaaatc ctgtccccgg agctgtcgga cgatatgctg gccgacttcc tcaatacgga
    16441 aagcggtgtt ttagtcaatc tccatgtgca ggccattgaa cagaccaagg cgatcaagac
    16501 catcaagcgc aaaattaccg accttgacgc tatgaagatt gcggagcaga aaaaggccgt
    16561 ccgcagcggt tacgatatgg acattcttcc cagcgacctt gccacctacg gcgaggacgc
    16621 caagaagctg ctgacaaagt tgcagacccg caatgaacgg ctgttccagt tgacgttcct
    16681 tgtcctcaac gtggccgaca ccaagcaaaa gctgaataac gacgtgttcc aagccgcagg
    16741 cgtggcccaa aagcataact gtccccttgt ccggctggac taccagcagg aacagggcct
    16801 tgcaagcagc ctgccgctgg gcgtcaatca gatcaagata cagcgcagcc ttacgacttc
    16861 cagcgtggcc gtgttcgtcc cctttgtgac gcaggagctt tttcagggcg gcgcggccat
    16921 gtattacggc atcaacgcca agtcccgcaa catgattatg ctggacagga agcaggcccg
    16981 ttgccccaat gccttgaagc tcggcacccc cggcagcggc aaatccatga gctgtaaatc
    17041 cgagatcgtc agtgtgttct taacgacgcc tgacgatatt tttatttcag acccggaggc
    17101 cgaatattac ccccttgtca aacggctcca cggacaggta atccggctgt cgcctaccag
    17161 caaggacttt gtgaacccgc tggacatcaa cctgaattat tcggaggacg ataacccgct
    17221 ggccctgaaa tccgactttg tgctgtcgtt ctgtgagctt gtcatgggcg gcaagaacgg
    17281 gctggaagcc attgaaaaga ccgtgataga ccgggctgtg cgcgtgatct accggcccta
    17341 tctggcagac ccccgcccgg agaatatgcc gatcctgtcc gacctccaca aagcgttgtt
    17401 agatcagcat gtcccggagg ctgaccgggt ggcgcaggcc cttgacctgt atgtgtccgg
    17461 ctccctgaac gtatttaacc accgtaccaa cgtggacatc ggcaaccggc ttgtgtcctt
    17521 tgacattaag gagctgggca agcagctcaa aaagctgggg atgctcattg tccaagacca
    17581 gatatggggg cgcgtcacgg ccaaccgaag ccaaggaaag gccacatggt attttgccga
    17641 cgagttccat ttgcttttga aagaggaaca gacggcggcc tattctgcgg agatttggaa
    17701 gcggtttagg aaatggggcg gcattccaac aggtgccacc cagaacgtca aagacctgct
    17761 ttcctccccg gaaattgaaa atatccttga aaacagcgac ttcattacgc tgctcaatca
    17821 ggcgtccggg gatagaaaaa tccttgcgga acgcttgaat ttgtccaccg aacagcagaa
    17881 gtacatcgac aattccgaac ccggcgaggg ccttttgatc tttgaaaacg tggtgctgcc
    17941 ctttaccaac cccatcccgc acaacaccca gctttacaag attatgacga cccgcttaaa
    18001 cgaggtggcg ggagtatgac ccggcgacgc cacaaaggag gtgaaccacc atgaaagagc
    18061 tgaaagccaa ggcgaaagtg acgcaggcca tgacccgcga cgggctgacg ctggaaaatc
    18121 aggccaccgg cgaggtggag aacatttcca gccgggaggc cgaacaggat ttgtccgcgc
    18181 cggggccggg cggcaccgcc gataagctgc tggaacgggc cgacgccatc catgacggcc
    18241 ataaggccaa gaaagccgcg aagcaggccg gggctgtggc cgccgagggg gacgctgccc
    18301 tgcaccggcc atccgcccgg ctccaactgt cggaggaaga acgggccgac ccggatttac
    18361 agccctatat ccgaaaatcg gacaaacggg ccgataagct ggataaggcc cgcgccgcca
    18421 tccccaagaa gcgcgtcccg gtcaaggaaa ccgtctttga cgaggcaagc ggcaaagcaa
    18481 agaccgtcct gcactttgac aaacaggaca aggggcctcc ctccctgaaa cccaatccgg
    18541 caggccgtcc tgtttccgag gtttttctat tcggccacgg gaaaatccat gaagtcgagc
    18601 atgaaaacgt gggtgtggag ggcggccata agggggagga acttgccgag cggcaggccg
    18661 gaaaagccat ccgcagcacc atccggcacc acaggctgaa accctactgg gacgcggaaa
    18721 aggccgagcg caggctattg tctgccaacg cggagtattt ctaccagaaa tctttgcggg
    18781 ataacccgga gatcgcacag gcggccagca accccatttc ccggttctgg cagaaacagc
    18841 agatcaagcg ccagtacgcc aaggccgccc ggacagcggg ccagaccgca ggcgcggcgg
    18901 cacagggcgc ggccaagaca gccggggcct ccacgaaagc ggccaaggcc gcagccaaag
    18961 aaagtgaacg ggcggcctcc tttgtggccc gccactggaa aggggcgctg gccgtccttg
    19021 tgttggggct tttgatgctg cttatcatcg gcggcttaca gtcctgcacc gccatgttcg
    19081 gcagcgccgg aagcggcatc acggcgtcct cttacttttc cgaggatagc gatatgttgg
    19141 ccgccgagga cgcctacgcg gagctggaag ccgagctgca agactatctg gacaactacg
    19201 aggccaccca tgactatgac gaataccatt ttgaccttga cgagatcagc catgacccct
    19261 atgtgctgat ttccattctg tcggcgctcc atgacgggat atttaccatc ggggaggtac
    19321 agggtgattt gtccatgctc tttgacaagc aatatatcct gacagaaaac gtcgtggtag
    19381 aaacccgtta ccgcaccgaa accgatacat ggacggacgc ggagggcaac acccatacag
    19441 acacctacca agtgccgtat gactattaca tctgctacgt cacgctggaa aacttcgacc
    19501 tgtcccatgt gccagtctat atcatggacg aggaaacgct aagtttctat tccctgtata
    19561 tgtccacgct aggaaaccgg cctgatctgt tttccggcag ccagtacccc aacgcctcca
    19621 ccctgacgcc gccgacctac tacgacgtac ccccggaggc tttggaggat gccacctttg
    19681 ccgccatgct caaagaggcg gaaaaatata tcggttatcc ctatgtgtgg ggcggcagct
    19741 ctcccagcac cagctttgat tgcagcggct tcatttcgtg ggtaatcaat catagtggat
    19801 ggaacgtggg acggctgggg gcgcagggcc tatataacat ctgcacccct gtttccagtt
    19861 cgcaggccaa gcccggcgac cttgtatttt tcaagggaac ctacgacacc cccggcgtgt
    19921 cccacgtcgg cctgtatgtg ggcaacaatg tgatgctgca ttgcgggaac ccgatttcct
    19981 acacgaacct tacttcaaac tactggcaat cccattttta cagttacggg cgtttacctt
    20041 aacgccagaa aggagctttc aattatggca accaaacttg accgcatcga aaaggacatc
    20101 cagaaaacca agtctaagat cgcggagttt cagaaacagc ttcgggagct ggaaacgcag
    20161 aaaaccgaac aggagaattt gcagatcatc cagcttgtgc gcggcatgaa catgaagccg
    20221 gaggaatttg ccgcgttctt acgcagcggc gcaatgcagg ccgcccctgc cgcaacccct
    20281 taccatgaac aggaggacaa tgcccatgaa gaataagacc agacggattt cccgtattct
    20341 ccccgcactt ctggccgtga tgctctgcgt cacggccttt cccgttaccg cccttgcagg
    20401 cggcaatgac ccggcaccgg ccccgctgcc ggaggctaca accgaacccg ctacgggcgg
    20461 tttggagcct gaaacagacg aaaccggcac cgccacggac gggacagaaa ccgaggccga
    20521 aaaagatacc ggccctctga ccggcaagga catcaccgac ctgttttccg cgctgttcgg
    20581 ttccaaggtg agcattgccg ccacggacga cggcatccag atcaccaccg gcaccgacaa
    20641 aaaagaacct gaacagaccg gcaccgtcac caccaacggc ggcaggctga atgtccgcac
    20701 cggcgcgggg cttgacaaga ccgcgttcac ccagcttccc aatgggacga cggttgaggt
    20761 agtcggcaca gacggcgact ggattaaaat tctcttgccg gagcgcatcg gctatgtcca
    20821 ttccgactat atgaccgtca gcgaaaagga agtagcggct accggcgagg gcggtttttc
    20881 cctctccatt gacccggagg aaattgcttc tctgctggaa ctgttcaatg gcggcggggc
    20941 cagcgccgcc ctgtccccgg acgggaacct gtcactgatt gacgacatcg gcagcgccgc
    21001 gaaaaatggc aagcagttta tcaccgtgga aaccaaaaac ggcaatgtgt tttatctgat
    21061 tattgaccgg gacgacgagg gaaaagaaac tgtccatttc ttaaatcagg tggatgaagc
    21121 cgatctgctg acgctgatgg aggacgggga aaccgtcacc cccgctgctg tctgctcctg
    21181 taccacgaaa tgcaaggccg gggctgtgaa cacgaattgc ccggtatgta aaaccaacct
    21241 gaccgagtgc agcggcccgg agccgcagga accccagccg gaggaacccg aagccccgga
    21301 ggaagaaccc aagggcggcg cgggcggcct gatcgtgttc ctgctggtgg cgctggcggg
    21361 cggcggtgcg gccctttact atttcaagtt caaaaagccc aaggctgaaa ccaccggcag
    21421 cgacgatttg ggcgagtatg attttgggga ggacgaggat ttggaggacg aggaacccga
    21481 aaccgagttt gacccggaag ctgattttgt gagtgaacag gaggacgagg aatgacatat
    21541 aaacttgtaa tcgcggaaaa acccagcgtg gcccgcagca ttgcgggcgt gatcggggcc
    21601 acggagaaac acgacggcta tttggagggg aacggctatc tggtgagctg gtgcatcgga
    21661 catctggtgt cctttgccga cgccggacgc tatgacgagc gtttcaaaaa atggcgctat
    21721 gaggatttgc ccattctccc ggaaacatgg cagtacatcg tccccgacga caagaaacag
    21781 cagtttgacg ttctctgttc gctgatgcag cgccccgacg tgaccggcct tgtgtgcgcc
    21841 accgacgccg ggcgcgaggg ggaattgatt ttccgtttcg tctaccagat ggcgggatgc
    21901 caaaagccct ttgagcgcct ttggatttcc tctatggagg acagtgctat taaggacggc
    21961 tttgcccacc tgaaaccggg cggcgactat gatccgctgt atcaatcggc cctgtgccgg
    22021 gccaaggccg actggctgat cggcattaac gccacccggc ttttttccgt cctgtaccac
    22081 aagaacctga ctgtgggccg cgtccagacg ccgaccttaa aaatgctggt ggacagggac
    22141 gccaagatta ccgatttcaa gaaagagaaa tatcacatcg tccatatcac ggcgggcggc
    22201 gcggacgcgg taagcagccg cttttccgac gctgccgagg caaacaccgt caaggcggct
    22261 tgtgcaaaag cgcaggccgt ttgcgtttcc gtgacgcggg agaaaaagac ggaacagccg
    22321 cccaagctct atgaccttac caccttgcag cgggaggcta accggctttt cggctatacc
    22381 gccaagcaga cccttgacta tgcccaggca ctgtatctaa agaagctgct gacctatccg
    22441 agaacggata gtcaatatct taccgacgat atgctgcccg ccgtggaaag ccttgtgtcc
    22501 ggcctgtggg agctggtgcc gtttgccaag ggcctgaacc tttccccgca gtttgaccgc
    22561 atcctgaaca gcaaaaaggt gtccgaccac cacgccatta tccccaccgc tgaatttgtg
    22621 aagcagggct ttggcactct ggccgagagt gaaaaaaagc tgctgtccct gatctgctgc
    22681 aagctcttat gtgccgtggc cgggccgcat atctatgagg ccgtcaccgc cacatttacc
    22741 tgtgccgggc aggagtttac cgccaagggc aagaccgtcc tttcccccgg ctggaaagag
    22801 attgaacgcc ggttccgttc ttccttaaag accgacgccg acgaggacgc cgaggcggtg
    22861 cgggagctgc cggagctttg cgagggccag acctttgcag acgtggccgc ctctgtcacc
    22921 gagcatttca ccacgccgcc caagccctac accgaagata cgcttttgtc cgctatggaa
    22981 cgggccgggg ccgaggatat gccggaggat gccgagcgca agggattagg cacaccggcc
    23041 acccgcgccg ccattctgga aaagctggtg cagatgggct ttgtccagag aaaaggcaag
    23101 cagctcattc ccaccaagga cggcatcaat ctggctgtgg tgctgccgga ggcgcttact
    23161 tctccccagc ttactgccga atgggaaaac cggctgaccg agatcgccaa ggggcaggcc
    23221 gatcctgacg aatttatgga cggcatcgag acgcaggcgc gggagctggt gcagacctat
    23281 tcctgtatca gtgaggaaaa gcagaaattg tttcaggccg agcgtgttcc tatcgggacg
    23341 tgtccccgct gtggtgaggc tgtctatgag ggcaagaaaa actactactg cggaaaccgg
    23401 gcctgccagt tcgtcatgtg gaagaatgac cgattttttg aggaacgcaa gaaagcgttc
    23461 accccgaaga tcgccgctgc gctgctcaaa accggcaaag tcaaggtaaa gggcctctat
    23521 tccgtaaaga ccggcaaaac ctacgacggg acggtgcttt tggctgatac cgggggcaag
    23581 tacgtcaact accgcattga acacaggagc taaaggacag taacacagca agcataggga
    23641 gtgtggctac actcccggta aaatcccccg gccgcgtccc tgccgggccg gggatttttg
    23701 cttgttgggg aagtccccaa ccccctattt tttgaaacag aacagagaaa ggagtgaccg
    23761 cgtgaacgaa gtattttcta tccaagtcca taaccggcag tttttggaac agggcaaaca
    23821 aggcgtctgg ctggatttgc ccaccacaac cgaaacgctg caagccgccc tgcgggatgt
    23881 tggcattact gccgacaatc cgcaggattt ttttatcaac gggtattcct gcccggagga
    23941 cagacacctt gccattccct atgacatggt gctggccgcc gacgtggacg agctgaattt
    24001 ccttgccgcc cggctgggcc agcttgacgc cgccgagatc gcagagctga acgccgccct
    24061 gcaaaatccc cgtggcggct ttgagaatat cggccagatc atcgactaca ccgaaaatgt
    24121 ggattactat gtgcatcttc ccgacgttag gggggatgga cagttgggcg actactacct
    24181 gaaccgttcc ggcatggtgg atatgccgga ggaatggaaa gccgggattg atacggcgca
    24241 gtttggacgc cacattgccc agcaggaaca aggcgttttt acccagtacg gctatctggt
    24301 gagaagcggc gacgaatggc agcgcgtcca tgagggccag ccggtgccgg aggaataccg
    24361 ggtgatgcac tacccccagc cggaagctga ccgggaggaa ccgcaggccc agcagccgga
    24421 ggcatccgaa agccccgaca aagcgccgcc cccggttatc ccgatcatgc tggacggcat
    24481 gaacagcaaa gaacgcatga aagtgattac tgaccgtctg gaaaccggcg tacaggagct
    24541 ttttgaaagt agccgctata tggcttactt atccgctatg tccaagatgc acgattacag
    24601 tctgaacaat acgctgctga tcgccatgca gggcggttcg attgtggcgg gctataacag
    24661 gtggcaggat gaatttgacc gccatgtgaa gcggggcgag aaaggcatta agatactggc
    24721 cccggccccg ttcaaggtta agcagcagat ggagaaaatc gacccggcca cccagcagcc
    24781 cgtgatcggc gcggacggca agcccgtgac cgaagaacag gaagtgacgg ttccggcctt
    24841 taaggtggtg acagtctttg acatcagcca gaccgagggc aaggattttc ccatgcccta
    24901 tatcagtgaa cttaccggcg acgtgcagca gtatcaggat ttctttgccg cgctggaacg
    24961 gacatcaccc tatcccataa gcattgagcc gatttcagac ggggccaagg gccgctgctt
    25021 ctacgcaaaa cagcgcattg ccatcaacga gggcatgagc gaattgcaga ccctaaagac
    25081 cgccatccat gagattgccc atgccaagct ccacgccatt gaccgggagg cccccgccga
    25141 ggaacaggcg gcccggccag accgcagcac ccgcgaggta caggccgaaa gcgtggccta
    25201 taccgtctgc cagtattacg ggctggacac gtcggactat tcttttggct atgtggccga
    25261 ttggagcagc ggcagggagt tatccgagct gaaagcctcc cttgaaacca tccgggccac
    25321 ggccagcgaa ttgataaccg agatcgacgg ccattttgcc cagcttcagc aggagcgcga
    25381 ggcccggcag gaacaggagg ccgtcacggt tgacgttacc ccggaggcag cggccccggc
    25441 gcaggccgag gaagaacagg ccccggccct tgatccggca gccgagccgc ttgtgactgt
    25501 gctatggagc gaaagccccc agctaaagga cggccagcaa atgccgttgc atgaggccga
    25561 cgcgctgttt gcccgtctgg atgcagcata tccggcagag gcaggctatg acaaaaccgc
    25621 gttccgcatt gactgtatct ttcagggcga gccggacagc tacgaggggc ggcaggattt
    25681 tggagatagg gacggttccc tgatcgaaca tatccagagc taccaccaat tttacgcgca
    25741 ggacgaaaac tggaaaaagc atgtaatcgc tacaaccggc atagagggct gggagcagga
    25801 caaggcccat cgggatatgc tgttaggcga gtttgtcccc tatatgaagc tgcattgcag
    25861 ccttgcccaa atggaacaga cggcgcaggg ccgcttacag tccggggaaa ccctgacgcc
    25921 ggaggaaacg gcctatttgg gggcgcttct ctcttatgtg caggagtgcc gccccatgct
    25981 caatcagggc cagtatcagt tgccggagcc gccgaaactg gctgacttcg accagagctt
    26041 gcaggactac aaagcacagg tacaggccga gatcgcgcag gaggccgccg cagccggtat
    26101 gaccgtggag gaatacgcgg cggctggcta tgaagcaccc caacaggaca ccttttccat
    26161 ctaccagctt cgaggcgggg aggaaacccg cgactatcgg tttgagccat acgagcgttt
    26221 acaggccgca gggctggccg tggacagtgc caactatgac cttgtttata cggcaccgct
    26281 ggataaaagc acgtctttgg aggatattta ccgcacattc aacatcgacc acccggcaga
    26341 ttttagggga cacagccttt ccgtttccga cgtggtggtg ctgcaccaga atggacagga
    26401 caccgcccac tatgtagaca gcttcggcta tatggaagtg ccggagtttt tgcgggaaaa
    26461 tcccctgcgt accgccgaac tgtctacgga gcagaacgaa aacatgattg acggcattat
    26521 caacaatacg ccgcccgaac cgcagccgga ggaacccgaa cagctatctt ttgaggatgt
    26581 ggcagttgct tccggccaga cacaggagga acccccggag gctgcgcccc cgcaaacggc
    26641 tgtccgctat tatcccatca atgagggagc cgcccgccgc gccaaggaag ccatgagctt
    26701 ttctgactac cggcccggca gcgccacggc ggaataccgg cactatgtcg atcaggccgt
    26761 ggaaattgcg gagcgccaga aaaagcgtgt ggagccagag tatcacgaaa agatagacag
    26821 cctccttgac acctacgccc gcaagctggc cgagaacatg aataagggct atgagattac
    26881 cgcccgcgtc ccctctgtcc tgattgccgg gccgtccaat ttcccggtac gggcgaaaga
    26941 aaagcagaac gccgccagtg accgcaacat ggaggaattt cagtacattc agggcttgct
    27001 tgacaaaatc cgcagcaccg gcatgggtgg tatcagcgcc gacgatccgc aggccgtttc
    27061 caagctggaa aagaaactgg aaaagctgga agcgtcgcag gagttgatga aggccgtcaa
    27121 tgcctactac cgcaagcatg ggacgctgga cggatgcccc catctgaccg aaagaggcat
    27181 tgaaaacctg aaagcggata tggcgtcggg ctggcactat gagaaaaaac cgttccagtc
    27241 ctggcagctc tccaacaata acgccgagat acgccggtta aagggccgca ttgaggaatt
    27301 gacccgccaa aaggaggcgg cctatgtggg atgggagttt gacggcggca ctgtggagat
    27361 caaccgggtg gccaaccgcc tgcaaatctt ctttgagggg aagccggatg ctgctgtacg
    27421 cgacgagctg aaaagcaacg gtttccgctg gtcgcccaag gccggggcat ggcagcggca
    27481 gttaaacgac accacaatcc gcgtcgctga ccgtatcaag tgcatccagc ccctttccgg
    27541 cgaaaagccc agcgccttac agcttgcggc ccgcagggag aaagaaaagc cctctatccg
    27601 ggcgcagctc aacgcggcca agaccgaaca ggccaagcag ccaccggcgc gggaaaaatc
    27661 aaagggattg gaggtagagt aaatgcagaa gtttgaaaat gtggacgttc tggccgcgct
    27721 ggaacagatc atgcggcaga acaccgcgtt ttatcaaagt gactttggca ttgacaaaga
    27781 cattatcagg cgggatgccg ccagcgatca ggccgcagac aagaccctgc tctggatgtc
    27841 ccggccctcc gggacgtact gtttccggga acgtgatgtt ttcctgaaag acacccgaca
    27901 gtacaacaca tggaaatttt acggggagca gacccgtgac aagatactgg cctacgcggt
    27961 ggagctgacc ggcacacagg gcggcactat ccggggcaat ctctatgagc tggactatcc
    28021 gcagcatttc cggcacgtca ttgaaaccgc ccagccggtg agtgtgaacc ggctctttta
    28081 tgagcatggc acccgtgaca tcccggagag ccagcgtttt gacggaagcc ctgaccgggt
    28141 attgggaaac tttttgtact atgaggccca gccccatgac ccggctgtgc tgcaggaggc
    28201 gctacggacg gagcagcaca gccgggggcg ggccgtcccc ggcgatttca aagtccacgt
    28261 caccgctttg catgacagcc ggattgaaac cgaggcccgg cgtattgtgg acagcctgaa
    28321 agatctgtcc gcgcctaaca gccccaataa aacgcatttc atggtggaga tctccccgca
    28381 ctttgcggcg attgcttcca ccaaggataa tgaccggctc tttgccatgc tgccctataa
    28441 atccctgtgt tttaccggga tgaaaggcag gcatggcgtg tatgccgtga ttaaccggga
    28501 cgagcgccgg gatgtgagta ttcgcaggcc ccggccctct atccgcaagc agctatccga
    28561 cagcaaacag gccgccagcc caaaaaaggc ggcggccaga accaaaaaga atgaattgga
    28621 ggtataagga atgatgcact ttaccgtgga ggaagaaaac ctgatctgta tgtaccacaa
    28681 tgcagaccgg cgcagaacga taaacaggct caccgccgtc atgccggtta tggatgggga
    28741 tatgcgggcg caggcccagc agaccctttc caagctggaa cgcatgacgg atgccgacta
    28801 tgacggccag aagttccact tcacagacga ataacgaaca gcagacgccg ggcgcggcgg
    28861 ccatgtggtc gcttgcgtcc ggcgtctttt ctttttgcct attcctacgc atttagaacc
    28921 cggtattgtc ggggatagga tgaagtattc gcttgcccct gcaaacatgc gggagaagcc
    28981 ttgcagcggg cggttttcaa tcccttaaat gcgtaggttg cagctataat tagacccctg
    29041 aaacagatat agccgcgcag cgggtgtatc tgtttcaggg gtgtgcaggt gatagccgca
    29101 aagcggcgta agagggtgca gccctcttgc cgtctatctc tgttccagcg ggaagctcgg
    29161 caatgcttcc agcagtttca gggaaatgcg ctgccgtata tcttcgtcaa tgactttctt
    29221 ctttttgccg tttgcctgtc tgatctccac cgtggaaagc tcgttgatgt agtcagcata
    29281 atgggccaac actttttccg tggcccacct ctcaccggca acggcggctt tgatcgtttc
    29341 atagtccagc agcttttctt gtccgtccat cctgataccc ccgtcagact gattttttct
    29401 atgataccat attcggaagc atggaaccag agaaaacggc gcttttctgc tggtaaattc
    29461 tacgcattta gaacagcact tcggcgggga taggataaaa cacccacata ccccgctgac
    29521 catgccggaa aagccttgaa atataagggc ttttacagct ctaagtgcgt aggtttccag
    29581 tatcttttcc gctggcgctc ggcctctttg cggcggcgca tccgtttgga gcaggccgcg
    29641 cagtatttgg cccggttaga cttcggcgtg aacgtggccc cgcactcaca gcagcgtttc
    29701 acttcgtccc ggtctttggt gatctcggca tacagggccg catccagcgg gaggacagcg
    29761 gccttaaacc agcggcacag aagcgaatag gaaatgctct gtacgcaaat acattcttcg
    29821 ccgtcgtcca gcaacaggca gttgccgtca caatagttgc agcactcatg cgtcagcttc
    29881 cgggccttgc gatattgagg gtaattcatt cgtggaatac tcatagctct tgcgtccatt
    29941 cctttcccgg cgtcatacgc aaaatgccgt ccacattctg cttgatgatg ccgtattcct
    30001 gcatctgctt tttcgcttcg ccgtacttct catacagccg ttccttttcc tcggccaatc
    30061 gcttgtactc ggctttcagg gcgtacagat cggggagctt tttcacaccc tgtcccttta
    30121 gggcctttgc cgcagcttca tacaaaatca acgtgctttc atgctcacgc cggaattttg
    30181 ccttatccgc tgcattgcgg tattccatag ccacgggcca gagctgcttg taggtagaaa
    30241 tattctttat cagcaccgcc atatccgcaa gccggtgttc catagctttg agggtagcgg
    30301 cggcctcgtc gctggcggcg gtgatctcgg ccactttgct ttccaaatcc gggtaggtgt
    30361 ctatcccatg ttcagtcagg aaattcaaag tctttgcggc ctgcttcaaa ttgtggagct
    30421 tcgcccacct ctcatagcct gccgactgct gggccttaat gttgttttcc agatcaatcc
    30481 gcaaagaaat ccccttgcgc tctttgggcg ctctggtgat aacgcggcct ttgatacgct
    30541 ctttgatggc ttcctcggtg taggcttccc ccaatgtctt gcagcgggta aagcgttcct
    30601 gtccgggagc gcggaaagaa ataaactttc ccggcttgat ctcatagccc tgcgcctgca
    30661 tgagccgcag gaaatcatca aaatcttttg cctgcgggat agcggcgtca atggctgctt
    30721 tgagcttcgc tttccagctc gtccctttcc gctgggcgtc ccactcggca tagctcttgc
    30781 ccttactctg gccgggcttc accacggaca atccgttttc cttgcacagc ctgtcgctgg
    30841 tgcgccggat ataggcatag ctctgtttgt tggaaatgta cttgcgctga tttaccatat
    30901 ccacggcaca gaaaataatg tgattgtgga cgtggccctt atcaatatgg gtagtcagca
    30961 catagggata tttcccttgc agcacttcct cggcaagctg cttcccgatc tcatgggcct
    31021 gttccggcgt ggcttcgccg ggggcaaagg attgtatcag gtggtggccc agattattgc
    31081 ccttttggta tgcctgcgcc agcagcattt caaattcaat gtccgctgtt tcataagagc
    31141 aggcaaagga ggccaccagc agcttgccgt cagttttgtc cgggttctcg atgtagtcaa
    31201 gggctttttt cagcgttgac ttgataggat gtatctttgt aactgccata tctgcgccag
    31261 cgcccccttt atatcctcga tgtcctgtgc gtacaccggc cccataccgt tcagcctctt
    31321 tgcaatctga ttgacgttga cgccgatctt ctgtatctcg gcggtctgcg cccggatgtc
    31381 gctggtgtcc atgttgacga tatagccgtc aatgagcatc ttccgggcgt aggctgaaaa
    31441 gttcttcgta tgcagcagcg ccattttctg ttcaatcata gcccgttcct ccggcgtcac
    31501 agggacgcgc agcacgattt ttcgctttct gtttgccatg cttcaccgtc ctttccattc
    31561 aggggtttgg ggatttcccc aacaagcaaa acggacgcgg cccggcaggg acggggcagg
    31621 ccgtttttcc gggagtggct acactcccta tgcttgctac gttactgttt ctccactaac
    31681 aagacgtttc caaagcccca aactacccgc aaaatagccc tctggaaaga aaaaagtgca
    31741 aaaaaataga agctacgctg tgcagctccc gctaaaagta aaacagagga tgccagttac
    31801 acatcctccg tttcattctt cttcggcttt tcaattagta tggcgctgtc aatcgcgccc
    31861 tcgatgatcg gcaggtattc ttcggggcag agtttcagct tgtggctgac cctttgccgc
    31921 agttcgcttt cctcccgcat gatctccggg ttaaagtagc gttccacagg aagcccgcag
    31981 gctttaataa gctgtatgac aaccggcaga ctgggaatgg ccccgtcgtt ttcgatgttg
    32041 gcaagatagc gccagtcaat atttattttc tctgccattg ctttgcgcga aacgcgcttt
    32101 gcttgccggg ccgctttcac atccgcgccg aaagtttcaa agccgggaca atcttcaata
    32161 ttcgccatat cgcacctccc acttacattg tatatttcat actctgcccg tggaatgttg
    32221 gtatatgcac ctttcttaaa gtttatattt cacattttgt ttcttttatt cttcgagcaa
    32281 aagaattata atgtaccctg tggaggtgta ctatggacta catgacgttg aaagaggcag
    32341 gcgagaaatg gggtgtgccc ccacgatgga taaactacta ttgtgctgcg ggacgcatcc
    32401 ccggcgctgt aaagatggcg acgatctggc tcattcccaa aactgcggaa aagccgattg
    32461 acaggcgtac aaagaaagga aaggcggtta ctgaatagta taatgaaacc ggcgcatttt
    32521 ggatatggtt ttgaagagag agaaagcatg gtattttgtc acggaaaaac tataagatga
    32581 tagatggcag gctgctccag accgataaaa agtattctca tctgaaacag aaagaaaaga
    32641 tttacacatg gatgtatgaa gaagcgaaac tttatcatga cagaaatgga aaatgcccga
    32701 aacaaagacg aggaagctgc tgctgtatca gccgtatatg gtagaattga aaaggccggc
    32761 atctggattc tttatggtga agtctccaga cattggataa ctgctggtct aatgcgcctt
    32821 tgagtatggg gtgattgatt ttaataccgg ggaggtacgg ctttttgagg aaaatattct
    32881 gggatttaca tttggcgatt attacatttc ctgtaactgc aaggacacgg atgatgaaga
    32941 tatgaggaat atagacttgc tgattttcta ctgtcttgaa cggtattagg actgaatctg
    33001 ctgcgcggag tgcggcaaga gcgaccggag ggagtacaca caggccctgc ctgtgtgaaa
    33061 agccataccg caaggtgcat tcgcaaaaaa gaggccgcgc attttgctga ggcttggggt
    33121 gtccccaaca agcaaaacga gaacgccgca ggcgggcaag tggtggatca gaatatccgt
    33181 aaaggatatt ctgatccatt gcttgccagt attatcggga tgttttgaca accgctgtaa
    33241 tcgaaacatc ccaaacatta agaaggtgtt aattattatt atcttgattt aattcgttta
    33301 aaccaataat atagatacat acaccatgaa aagaagcgag tatcccaatg acggatgatt
    33361 aaaatccgaa aagaaatcgc tttgaaacta cagggaaact acagactgtt atgttatctt
    33421 cttaaaatgg agggattttt atgtcgatac gaattctact tgtcgaggat gatgatcata
    33481 tctgtaatac agtaagggcg tttctggctg aggcaggata tcaggtggat gcctgcacag
    33541 atggaaatga ggcatacacc aagttttacg aaaacactta tcaactggtt attcttgata
    33601 ttatgctgcc cggtatgaac gggcatgaac ttttgcgtga atttcgtgcg aaaaatgata
    33661 ctcccattct gatgatgaca gccctgtcgg atgacgaaaa ccaaatccgg gcgtttgatg
    33721 cagaggcaga cgactatgta acaaagccat tcaagatgca gattttacta aagcgggtgg
    33781 aagccctgct gcggcgcagc ggtgcgctgg caaaggaaat ccgtgtcggc aggctgacac
    33841 ttctgccgga ggatttcacg gtactttgtg acggtacaga gctgcccctg acacgaaaag
    33901 aatttgaaat ccttttgctg ctggtgcaga acaaaggcag aaccttaacg catgaaatca
    33961 ttttgtcacg tatatgggga tatgactttg agggtgatgg cagcacagtc cacactcata
    34021 tcaaaaattt gcgggccaag ctgccggaaa atatcatcaa aaccattcgc ggtgtaggat
    34081 accgattgga ggaatcataa taatggaaag aaaagggatt ttcattaagg ttttttccta
    34141 tacgatcatt gtcctgctac tgcttgtcgg tgtaacagca acactgtttg cacagcaatt
    34201 tgtgtcttat ttcagagtga tggaattaca gcaaacagta aaatcctatc agccattggt
    34261 ggaactgatt cagaatagcg ataggcttga tattcaagag gtggcagggc tgtttcacta
    34321 caataaccaa tcctttgagt tttatattga agataaagag ggaagcgtac tctatgccac
    34381 accaaatgcc aatacatcaa atagttttag acccgacttt ctttatgtgg tacatagaga
    34441 tgataatatt tcgattgttg ctcaaagcaa ggcaggtgtg ggattgcttt atcaagggct
    34501 gacaattcgg ggaattgtta tgattgcgat aatggttgta ttcagccttt tatgcgcgta
    34561 tatctttgcg cggcaaatga caacgccgat caaagcctta gcggacagtg cgaataaaat
    34621 ggcaaacctg aaagatgtac cgccgccgct ggagcgaaag gatgagcttg gcgcactggc
    34681 tcatgatatg cattccatgt atgtcaggct gaaagaaacc atcgcaaggc tggaggatga
    34741 aatcgcaagg gaacatgagt tggaggaaac acagcgatat ttctttgcgg cagcttctca
    34801 tgagctaaaa acgcccatcg cggctacaag cgttctgttg gagggaatgc ttgaaaatat
    34861 cggtgactac aaagatcatt ctaagtatct gcgcgaatgc atcaaaatga tggataggca
    34921 gggcaaaatc atttccgaaa tactggagct tgtcagcctg aatgatggga gaatcgtacc
    34981 catagctgaa ccgttggaca tagggcgcac ggttgccgag ttgctgcccg attttcaaac
    35041 cttggcagag gcaaacaacc agcggttcgt cacagatatt ccagccgggc aaattgtcct
    35101 gtccgatccg aggctgctcc aaaaggcact atccaatgtc atattgaatg cagttcagaa
    35161 cacgccgcag ggaggcgagg tacggatatg gagtgagcct ggtgctgaaa aatgccgcct
    35221 ttttgttttg aacatgggcg ttcacattga tgatactgcg cttccaaggc tgttcacccc
    35281 attctatcgc attgatcagg cgcgaagcag aaaaagtggg cgaagcggtt taggacttgc
    35341 catcgtacaa aaaacgctgg atgccatgag cctccagtat gcgctggaaa acacctcgga
    35401 tggcgttttg ttctggctgg atttaccgct cacatcaaca ttgtaaatat ttaaaactta
    35461 aatgattttg accgacaggt ataaccctgc cggtcttttt ttgctgctac aggaaaacta
    35521 cagactggct acagggaaag tacagatgcg cttgccataa taacaatcgt accagccaca
    35581 aatcgtagtt ttattgcaaa ggaggcattc gatcaaatgg aaaaaagcaa ctatcattcc
    35641 aatgcggatc atcacaaacg gcatatgaaa caatccgtgg aaaagcgggc ttttctatgt
    35701 gcgttcatta tttcgttcac agtctgcacg ctgtttttgg ggtggagact ggcttccgta
    35761 ttggaggcaa cacagatacc gcccatccct gcaactcata caggcagcag cactgacgta
    35821 gtggagaatt tggaggaaaa cgctcttgcc accgccaaag aacagggaga tgaacaggaa
    35881 tggagcctga ttttagtgaa caggcagaac cccatccccg cacagtacga tgtggagctt
    35941 gagcaactat caaatggtga gcggatagat attcggattt ctccctatct tcaagatttg
    36001 tttgatgccg caagaactga tggagtttac ccgattgtcg catccggata ccgaacaaca
    36061 gaaaaacagc aagaaattat ggatgaaaaa attgccgaat ataaggcgaa aggctacacc
    36121 tctgcacagg ctaaagcgga agcagaaact tgggtggccg tgccgggaac gagcgagcat
    36181 cagcttggtc ttgctgtgga tatcaatgcg gacggaattc attcaacagg caacgaggtt
    36241 tatagatggc tggatgaaaa cagctatcgt tttggtttta ttcgtcgcta cccaccagac
    36301 aagacagaga taaccggtgt gagcaacgag ccgtggcatt accgatatgt tggcatcgaa
    36361 gctgccacag agatgtacaa ccaaggggtt tgccttgagg aatatttaaa accagaaaaa
    36421 tgagaaaagg atgttatgtt atggacagaa aaagattgac acagcgtttc ccgttcctgc
    36481 ttccaatgag acgggcgcag agaaaaatgt gcttttatgc gggaatgaga tttgacggct
    36541 gtcgctatgc gcagacgata ggggaaaaat cgctttccca tttgctcttt gaaacggatt
    36601 gcgcattata caaccacaat accggatttg acatgatata ccaggaaaac aaggtgttca
    36661 acttaaagct ggcagcaaag accttaaacg gcttattgat aagaccgggg gaaacctttt
    36721 ctttctggtg gctggtacgc catgcggaca aagatacccc ctataaagac ggccttacgg
    36781 tgaccaatgg taaactcacc accatgtcgg gcggcggtat gtgccagatg agcaatttac
    36841 tattttggat gttcctgcat acgccattga caattatcca gcgcagaggt cacgaagtaa
    36901 aggagtttcc agagccaaac agtgacgaga ttaaaggggt ggatgcaacc atttcagagg
    36961 gctggattga tttaaaagtg cgaaacgata ccgactgcac ctaccaaata tgggtgacct
    37021 tagatgatga gaaaatcatc ggtcaggtgt ccgccgacaa agagccccaa gcattataca
    37081 aaattacaaa tggcagtatc cagtatgtcc gtgaaagtgg cgggatttat gaatatgccc
    37141 aggttaaacg gatgcaagtt gccttaggta ccggggaaat aatagattgc aagctgcttt
    37201 atacaaacaa atgcaaaatc tgttatcccc tcccggaaag tgtggatatt caggaggaga
    37261 accaatgaga aaaagtgtgg gcattactgt ttttggatgc gaacaggatg aggcaaatgc
    37321 tttccgcgct ttatcgccgg attttcatat tatccctacg ctgattagcg atgcgatatc
    37381 ggcagacaac gcaaaattgg ccgctggcaa tcaatgcgtt agcgtaggcc ataagtccga
    37441 ggtttccgag gcgacaattc ttgcgctgag aaaggtcggg gtaaaataca tttctacccg
    37501 cagcatcggc tgcgatcaca ttgatacgac tgccgccgag agaatgggaa tctcggttgg
    37561 cacggttgcg tattcgccgg acagcgttgc ggattatgct ttgatgctga tgctgatggc
    37621 catacggggt gcaaaaccca ccatgcacgc cgtggcgcaa caagatttca gattggatcg
    37681 tatccggggg aaagaactgg gggatatgac tgtgggagtt attggaaccg gccatatcgg
    37741 gcaagcggtc gtcaaaaggc tgcggggatt tggatgccat gtgctggcct atgataacag
    37801 ccgaaaaatg gatgcagatt atgtccagct tgatgagctt ctaaaaaaca gcgatattgt
    37861 tacgctccat gtgccgcttt gtgcggatac ccgccatctg atcggtcaga agcaaattgg
    37921 agagatgaag caaggcgcat ttttaatcaa caccgggcgc ggagcgcttg tcgataccgg
    37981 ggcgctggtg gaggcgttgg aaagcggaaa gctgggtggt gcggcactgg atgtgttgga
    38041 gggcgaggat cagtttgttt ataccgattg ctcgcagaaa gtgcttgacc atcccttttt
    38101 gtcgcagctt ttaaggatgc cgaatgtgat catcacaccc catacggcgt actacactga
    38161 gcgtgtgctg caggatacta cagaaaaaac aatcaggaat tgtctcaatt ttgaaaggag
    38221 tttacagcat gaatagaata aaagtcgcaa tcatcttcgg cggttgctcg gaggaacatg
    38281 atgtgtcggt aaaatccgca atagaaattg ctgcgaacat tgatacggaa aaattcgatc
    38341 cgcactacat cggaattaca aaaaacggtg tatggaagct atgcaagaag ccatgtacgg
    38401 aatgggaagc cgacagtctc cccgccatac tctccccgga taggaaaacg catgggctgc
    38461 ttgtcatgaa agaaagcgaa tacgaaacac ggcgtattga tgtggctttc ccggttttgc
    38521 atggcaaatg cggggaggat ggtgcgatac aggggctgtt tgtattgtct ggtatcccct
    38581 atgtgggctg tgatattcaa agctccgcag tttgcatgga caaatcactg gcctacattc
    38641 ttacaaaaaa tgcgggcatc gccgttcccg aatttcaaat gattgataaa ggtgacaagc
    38701 cggaggcggg tgcgcttacc taccctgtct ttgtgaagcc ggcacggtca ggttcgtcct
    38761 ttggcgtaac caaagtaaac ggtacggaag aacttaacgc tgcgatagaa gcggcaggac
    38821 aatatgatgg aaaaatctta attgagcaag cgatttcggg ctgtgaggtc gggtgtgcgg
    38881 tcatggggaa cgaggatgat ttgattgtcg gcgaagtgga tcaaatccgg ctgagccacg
    38941 gtatcttccg catccatcag gaaaacgagc cggaaaaagg ctcagaaaat gcgatgatta
    39001 cagttcccgc agacattccg gtcgaggaac gaaatcgggt gcaggaaacg gcaaagaaag
    39061 tatatcgggt gcttggatgc agagggcttg cccgtgttga tctttttttg caggaggatg
    39121 gcggcatcgt tctaaatgag gtcaataccc tgcccggttt tacatcgtac agccgctacc
    39181 tacgtatggt ggccgccgca ggaatcacgc ttcctgcact gattgacagc ctgattacat
    39241 tggcgttaaa gaggtgataa gtatggaaaa tggttttttg tttttagatg aaatgttgca
    39301 tggcgtccgt tgggatgcca agtacgccac atgggataac ttcacaggaa aaccggtgga
    39361 tgggtatgag gtgaatcgca tcatcggcac aaaggccgtg gcgtttgctc tgcgcgaggc
    39421 acaaatccat gcggctgcgc ttggctatgg cttgctttta tgggatggat atcggccaag
    39481 aactgcggtg gactgcttcc tgcgttgggc agcgcaaccg gaggacaacc tcacaaaaga
    39541 aaaattttac cccaatatag agcgagccga gttgattaca aagggttatg tggcctcaca
    39601 atccagccat agccgtggaa gcgcaattga tcttacgctc taccacctgg atacagggga
    39661 acttgtttca atgggaagta acttcgattt tatggacgaa cggtcgcatc atacagcaaa
    39721 agggataggg gatgcagagg cacaaaatcg aagatgcttg cgtaaaatca tggaaagcag
    39781 cggatttcag tcttatcgct ttgaatggtg gcactataag ttgattgatg agccataccc
    39841 cgatacctat tttaattttg ccgtttcata atgaaagtat tggttttgta tcagattttg
    39901 gatttgataa aatctatgct ggtcatggac aatcttttac tggaaagtgg ttaaagcatc
    39961 ttttgtaata cattgcaaat tatagtattc aatctgccca gcggcagaaa agaaaaaaac
    40021 cgctgttggg cagacctttc ccacgcccat tttgtatttt gctggcggcg gttttgagaa
    40081 atcaaggccg ccgttctttt ctggcagcaa aaggtgtggc ggcccatagg aggatgccgc
    40141 tatgctgttt tgctattgcc atgctctaat ccacttccac cactcaaaaa aagccttgcc
    40201 cctccatgat gtgcacccca aaagttagac tagaaatcta attaa
//
LOCUS       DAMEEU010000224        10346 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.091, whole genome shotgun sequence.
ACCESSION   DAMEEU010000224 DAMEEU010000000
VERSION     DAMEEU010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 10346)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10346)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10346
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.091"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            78..974
                     /locus_tag="PB779_003023"
     CDS             78..974
                     /locus_tag="PB779_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HDE0740456.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(1124..2065)
                     /locus_tag="PB779_003024"
     CDS             complement(1124..2065)
                     /locus_tag="PB779_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HDE0740457.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            2191..3312
                     /locus_tag="PB779_003025"
     CDS             2191..3312
                     /locus_tag="PB779_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HDE0740458.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            3570..5072
                     /gene="eat(A)"
                     /locus_tag="PB779_003026"
     CDS             3570..5072
                     /gene="eat(A)"
                     /locus_tag="PB779_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HDE0740459.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            5100..5666
                     /locus_tag="PB779_003027"
     CDS             5100..5666
                     /locus_tag="PB779_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HDE0740460.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            5877..6938
                     /locus_tag="PB779_003028"
     CDS             5877..6938
                     /locus_tag="PB779_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HDE0740461.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            6941..7837
                     /gene="murQ"
                     /locus_tag="PB779_003029"
     CDS             6941..7837
                     /gene="murQ"
                     /locus_tag="PB779_003029"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HDE0740462.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            7851..9833
                     /locus_tag="PB779_003030"
     CDS             7851..9833
                     /locus_tag="PB779_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HDE0740463.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(9898..10344)
                     /gene="nrdI"
                     /locus_tag="PB779_003031"
     CDS             complement(9898..10344)
                     /gene="nrdI"
                     /locus_tag="PB779_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HDE0740464.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
BASE COUNT         3379 a         1833 c         2250 g         2884 t
ORIGIN      
        1 ggaaacgttt tactggcttt ttactattta aacaggctat cataggaaaa agtgacagag
       61 aaagtgaggc ggaaaagatg aacaaaaatg acgtactgct agttgcaaaa aataaatcac
      121 tttatttttt gccttccatc cgctctttag atgtttggtc cggaaaagat ttactacagt
      181 cggaattcat taaatcagct agacaacagt tggcaaatta tcagctgatc gtttttttag
      241 attatggatt tgatatggag atggctcgac gcgtgcgccc atttaccaat gcaaaaattg
      301 tgttattttt ttggaatcac ttcaaagcag aacacgaggc gatgctgaag caggcacaag
      361 atgaaccggc aatcgatgag atttatcatt ttgatttttt ggaagcaaaa gaacttgggc
      421 tgaaacataa tagttcattt tattcgaaac atatgaattt ttcttctagc gaaccaaaga
      481 cggatctatt ttttggtgca acgaataatg ggagaaaaga acgagcagaa agctataagc
      541 aggaatttat aaaaagagat gttacgacca actatttcat tcttccacat cgagggaatg
      601 aacaacctgg atatcttact tatgaagagt acctgaaaaa aacaggggaa tcgcgcggga
      661 ttctggaact gttgcgggag ggtcagcaag gagtgacttt gcggacattt gaatccatgt
      721 attttcaaaa gaaactagtg acggataatc aagcgattgc tcattatcat ttttatcgtc
      781 ctgaaaatat ttttttgctt cgagaacgtg atttagatga attaccggaa tttctgcata
      841 caccatttaa gccaatccta tcagagctat tggaatttta tgatgcagaa aattgggcaa
      901 aacgatttat cactaacgat tccactattt atgagcaata cgaatatgac ctctcctctg
      961 ttgaaaacaa ataaaaaacc tacattttga agagattatg tactgaaaca aacaagcaca
     1021 attcttatgg catcatgaga gttgtgtttt ctttttgatc ttttattggg cttaaaaaaa
     1081 gagaaccagc tgctgattca gctgattctc atcagagagc cttttattct gcgccaagga
     1141 ttccttcttt tgcatggact aattgggtca aaaaggcaca atatggtgta gcaatatcat
     1201 atttttgtcc ttttcgccaa atggcaccat tgatgtagtc gatttcagtc aaacgatggt
     1261 ttttgatcag gtcttggtac atagatgggt aatgcaaccc gatgttgtca ggatcataag
     1321 tagaagcaat atgttggtac acttcttctt gatctagtat gattccttct tttgctgcga
     1381 tagaagcaaa ttcagatacg attgttcgaa ccatgctctc tgccgctttt tgcgcgccta
     1441 gttcagcaat attacaatcc aaaatcgtgc ataaaccatt caatgttcca tttacacaag
     1501 cttttcgcca aatggaataa cgaacgttat ggctatagat cggatttaaa tttgcttctt
     1561 gaaagacttc tacaactttt tttgtaaatg cttcgccttc tggttccaag ttctctagtt
     1621 cgatttctcc atcacctaac aatgtgactt ttccgggacc agctagacca gctgtccaca
     1681 tcgtgatccc aaataagata tttttctttg gcacatattt ttccagtaca tcttcatgac
     1741 ctaatccatt tagtaaacac aaaacataag tattgtcagt aataatggat tggatcgaac
     1801 aaaacatatc atctaattga ttggcttttg ttaatgctac gatcaagtcc acgtgttcgt
     1861 tgctttcgat gatttcttct ggtgaataga ttggcagttt tgcgaccact tctttaccgt
     1921 taaagtcagc aatcaaccca tttgtacgaa tggcttcaat gtgagcaggc caacgatcga
     1981 tcaagaggac ctcatttccg ctttgatgta gcatcaatcc gattcggctg cccattgctc
     2041 cggccccagc tattgcgatt ttcatgtttt ttctctcctt tattcaatga gttccctttt
     2101 agtatataga aaaatggaag aaaatagcat tgttttgttt gaaaaaaatg aaaaaaagtg
     2161 tcttacttaa gaagaaagtg agggatacag atggatattt tggcggcaat tgattcattt
     2221 aaaggaagtg cttcttcatt tgaactaaat caggcagttc taaatggctg ggaagatcgt
     2281 aaaggaagaa aaatcaatgt gccgattgca gatggcggag aaaatactgc agaagcaatc
     2341 tattacgcgc tcaggggaac atggcgtacc attgatggga tggatctctt attccgtcag
     2401 cgaaaaatca gctatttatt gacaacttgg caaggaaaaa acaccgcagt catcgaatct
     2461 gcacaagcat tggggttaga tctacttgat aaaccaacgg atcaaactat ccgacttgct
     2521 tccagttatg ccttaggaga acttattaaa gatgcactgc ttcaagaagt agaacaaatt
     2581 attgtcactt taggaggaag cgggtgtagc gatggtggtc taggattact ccaatccttg
     2641 ggtgcttctt tagaagggta cacagaagga aatcctttat tatctactaa aaaacttcat
     2701 tttgatcgaa gaaacgttct tgtttctaaa gtaaaattga ttatcgctgc agatgttacc
     2761 aatccatata caggtcaaca aggagctgct tggcaatttg gaagacaaaa aggaggaata
     2821 gatacgacgc tagctttctt agataaacaa gcaggaaaga ttgctcagca aataaaagat
     2881 ttctgggagg tggatttaga tgatattcca ggaagtggag cagcaggcgg tattggtgga
     2941 gccctttttt tgttgggagc gaagatggtt tctggtttcg atttagtcag ccaaatcact
     3001 ggattggaaa aaaagatcga acaagcagat gtcatcatta caggagaagg gcggatcgat
     3061 cagcaaacga tccacggaaa agttccatac ggtgtagcag tgcttgcaaa aaaatatcga
     3121 aaaccaataa tcgctatttg cggaagtaga gaccaagagc tagaaggact ttctgatttt
     3181 ctcccaattg tcttaagtat tcatttgggt ccaataggtt tagaagaagc aatggaacac
     3241 aggcaaacat tagaaaaaac aaaaatctta ggacagacac ttagcagatt tttcaccatc
     3301 ctcccgaagt agttgacaaa atcattttct ttatgctatc gtaatttcaa atataggaca
     3361 aagtgaggga tccgtgcatt gaaaaattaa gtcgattgat gaaagctgca ttcagactgt
     3421 accttgtgga gacaaggaag cagtgtgcag attttcggga ttggcttggt tttttcgatg
     3481 tatgggtctt tttgtgtgta tccaaccctt gcatcctctt tagccagttc tgaaaatagg
     3541 actggtcttt ttttacgagg tgatggaaaa tgtctaaaat cgaaataaaa aatctgacat
     3601 tcggctacga cagccaaggc acattattat ttgaacaagc aaatctaaat tttgacacac
     3661 aatggaaact aggacttatc ggacgaaacg gtcgaggaaa gacaacttta ctgaatattc
     3721 tacaaaacaa actaccttat caagggcaag taatccatca gcaagaattt gcctatttcc
     3781 cgcaacagac aaaagataaa gaacgtttaa cctattacgt gttaaatgat attacggatt
     3841 ttgagatatg ggaaatcgaa agagagctcc aattgatgca aacagatcct gaaatcttat
     3901 ggagagaatt cagcacacta tcggggggag agaagacaaa agtcctactg gcacttttat
     3961 ttgtggatga cactcatttc ccgttaatcg atgaaccaac gaatcatttg gatatctctg
     4021 gtagaaaaca agtagcggct tatttgaaaa agaaaaaaca aggcttcatc gtggtcagcc
     4081 atgaccgggg atttatcgat gaagtagtgg accatgtttt agcaatcgaa aaaagtcaac
     4141 tggaacttta tcaagggaat ttctctatct atgaagaaca gaaaaaactt cgtgatgaat
     4201 ttgaaatggc tcaaaatgaa aaattgaaaa aagaagtcag taggctaaag aaaacagcag
     4261 ctgaaaaagc cgaatggtct cgttcccgag aaggagataa aacaaagaaa caagtcggat
     4321 tcatcgatac tgaatctaga cgagtgaata aaggagcagt gggtgctgat gctgcacgga
     4381 cgatgaaacg atccaaagca atcgtgaatc ggatggagac ccagatcagc gagaaagaaa
     4441 aactattaaa agatatcgaa tatatcgatt ctttgacgat gaatagccaa gcgtctcacc
     4501 ataagcgact tttaagcgta gaagatcttc aattagggta tgaaaatctg ttattcgagc
     4561 caattcattt tacaatcgag cctcatcagc gggtggcgat ttcaggtcct aacggtgcag
     4621 gaaagtcatc cattatccat tatcttctgg gggcattcaa cggcaaggtt ataggagaaa
     4681 aataccagcc aaaacatctg agcattagtt atgcaagcca aaattatgaa gacaatcgag
     4741 gaacgttggc ggaatttgca gagaaaaacc aagtagacta ccaagcattt ttgaacaacc
     4801 tccgaaagct tgggatggaa agagatgttt ttcataacaa gatcgagcag atgagtatgg
     4861 gccaacggaa aaaagtggaa ttggctaaat ctttatcaca gccagctgaa ctatatacat
     4921 gggatgaacc attgaattat ttggatgtct tcaatcaaga acaattagaa caactgatct
     4981 tgaacgtgaa acctgccatg ttactagtgg aacatgatca aaccttcctg gataaagtat
     5041 ctactgagat tatttctctt gagagaatct aacccttgta atctcaagaa caacaaggta
     5101 tggttaaggg gaactttgcc aacgaaggag agaatcacat gctttatgta acgagacacg
     5161 gagaaacaac ttggaacgca caaggattag tttgcggacg ggcagatgtg ccgctgactg
     5221 aaaaaggaca gatgcaggca cagaaactag cagaaaaggt agtagatttg cctgttccaa
     5281 tcacgaaaat catccattcc cctcttcaac gagcaagaga tacagcacaa gcagttgctg
     5341 atcgtctcag cttgccgctg accgttgatg aacgattggt agaaatggat tttggggatt
     5401 atgatggact gccaagcaaa gatgagaact ttcaaaaagc acgtttagcg ttcgctgtac
     5461 gattcccaaa tggggagtca gtcttagatg tgtatgcacg gatcgttcct ttattgaaag
     5521 aatgcatcga agacgaagaa aatgtctatc tgttagtttg ccataatgcc ttgataagag
     5581 tgatcaatgc ttattttcat ccgatgccta atgaggggtt ctttacattc atggtagata
     5641 atacagaatt ggtttcttat gagtaattat gtttttgtgt tatttaaata aaatatttca
     5701 aggcactgct tttgcttagc agtgcctttt ttaggttatg acaattcttt tgataatata
     5761 aactcaacct ttagaaatga aatttaatta ttttaataaa agtattgaaa ttttgtttct
     5821 ttagatatat actctagtca tagaaatgaa gacggataca gaaaaagagg gataatatgt
     5881 ttggcttttc aatatttatg aacgattctt tgtcagaaga gaagaaacag tatatccgcc
     5941 aaatggcatc caatggcttt gtcggtattt tcacttccat gcatatacca gaagatgatg
     6001 tttcggcata tcaaaagcga ttgatcgaac taggaagcga agcgaaaaag aataaactag
     6061 aattgatggt cgatatttca ggagaggcat tggaacgagc gggtttttca ttagaagatc
     6121 taacgccttt gaaagcaatt ggtgtaacag gtttaagaat ggattatcat atttccaatc
     6181 agcagattgc cgactggtca catcaattga aaatcagttt gaatgctagc acgatcacgc
     6241 ctaaagatat cgatgaattg aaagaagcag aagctgattt ctcacagatt gaagcttggc
     6301 ataattatta tccacgtccc gaaacagggc tggacaaaga atggtatcag aaaaaaaatc
     6361 aatggctcaa aattcaaggt ctccttgtcc aaggttttgt accaggagat acagagttga
     6421 gaggcccact atatcaagga ttgccaactt tggaagaaca tcgagggatc catcctcttg
     6481 caggcgctct agatctatta gcaagtaaca cggatattgt ttacatcgga gatgcaggtc
     6541 tgtcagaaaa cgttcaggag caatttgctt ctttccaaaa agaacagaca gtcttgctcc
     6601 atacggaacc tgtagatgaa gaattttacg aatatatatt agggaagcat acgaatcggc
     6661 aagacgatgc aagagatgtc atacgaagcg tagatgcacg ttttcgagag attccgccta
     6721 tcccagcaag aaatacagct acgcgtatga aagggtctat tactttagat aacgaaaagt
     6781 atttgcgcta tatgggtgag atccaattaa ccaaatatga tttgccagcg gatgaaaaag
     6841 tgaatgtagt agctaaagtt atcaaagaag agctaccatt gatcaaccaa atcaaagctg
     6901 gtatgaacta tcaatttata agaaaagaag gaagataaaa atgagcaaaa tcaatttaga
     6961 gaacctaaca acggaacgca gaaaccaaga aacttttgga ttagatgaga tgagtatttc
     7021 tcaagccgtt caactaatga acaaagaaga tcagaaagtg gccgctgcgg ttgaaaaaga
     7081 actgacaagt atcgaaccag tgattgctaa cacgattgag tcctttaaaa aaggtggacg
     7141 tctgatttat atgggagccg gaacaagtgg aagactaggt gtgttagatg ctgctgaatg
     7201 cgtaccgaca ttcggtgtag aaccggaaat ggtcataggt ctaattgctg gtggagaaga
     7261 agcaatgact gtagctgtcg aaggggccga agattcttat gagctagggc aagaagatct
     7321 aatcaagctg aatttgacaa aaaatgatat agttattggt atcgcagcta gcggtcgtac
     7381 accatatgtg atcggtggat tagattacgc aaaatcgatc ggtgctgtca caggaacgat
     7441 ttcttgcaat aaacaagccg aaatcagtaa acacgcggat ttcccaatcg aagtcgatgc
     7501 aggtccagaa tttttgacag gctctactcg attgaagtca ggaacagcac aaaaacttat
     7561 cttgaatatg atttctacta tcagtatgat tggtataggt aaagtattca ataacttgat
     7621 ggtcgatgtc aaaccaacaa atgaaaaact aatcgaacgc tcaaaacgaa tcatcatgca
     7681 agcgacagaa gctgattacg aaacagctga aaagtacttt gaagaagcag atcaaaatgt
     7741 taagctggct atcgtcatga ttttgacaaa tagtgataaa gaggaagctc aagcaaaatt
     7801 agctgaagca aacggatttg taaaagggac cttatgaggg ggaaaagacc atggcaaaaa
     7861 acgaactgac tttggaagaa ctggcaaaac aaatttataa aggggcaggc ggcatgggca
     7921 atgtagaaag cattgtccac tgcatgactc gtgtgcgtat gaagatcatc aatgatgatc
     7981 ttgtaaatgt ctctgaatta aaagcgattc caggagtgct tggtgtagta gaagatgaac
     8041 agcttcaagt catcatcgga cctgggaaag tgaacaaagt agcacagcaa atggttgatt
     8101 tggcaggcgt gaaattagga gaaaaacttt cttctgtaag tacagctaca gcaaattcat
     8161 cagcatctgg aaaagaccgt gtaaacgaac gggcacaaga aatgaaagcg gcacaaaaat
     8221 cgaaacaaaa accatctaaa atcaaatcgg tattaaaaga catttctaat atctttgtgc
     8281 caatgattcc tgcatttgtc ggtactggga tcgtggcagg gattgccgca gttttagcaa
     8341 acttagtcac agccggaaca cttgatgcag caacatggca acaatatatc gatgtgatga
     8401 acatcttgaa aaacgggatg tttagctacc tagttatcta tacaggtatc aatgctgcac
     8461 aagtttttgg tgcaacacca actcttggtg gagttatcgg ggccgttgtg atgctgacag
     8521 ggatgaatcc ggaagcacca ctgaaaaact tatttactgg tgaagctctt gcagctggac
     8581 aaggtgggat cctaggtgtc atcttcgctg tttggctatt gtcaatcgtt gagaaaaaac
     8641 tgcataaagt agtacctgat gcggtagata tcatcgttac accaactctt tcattgattg
     8701 ccatcggtct gattgaaatt ttcttcatca tgcctttagc aggtttcatt tctgatggca
     8761 tggtcggtgg gatcaactgg gtacttggcg ttggtggagc atttgccggc ttcgttctag
     8821 gcacattatt cttgccgatg gttatgttcg gactgcatca aattttgact ccaatccatg
     8881 tgcaaatgat tgatgaaact ggtcgtacgc tattgcttcc aattcttgcg atggctggtg
     8941 caggacaagt gggtgcagca ttggcattat ggattcgctg caaaaaagat aaagaattaa
     9001 cagaaatgat caaaggagct ttaccagtcg ggatcctagg aatcggcgaa ccattgattt
     9061 acggagtaac attacctcta ggacgcccat ttattactgc ttgtatcggt ggaggtatcg
     9121 gcggggcagt gatcggaatg atcggaaatg tcggggctat cgctattgga ccttcaggag
     9181 ccgctttgat cccattgatc tctgacggta aatggttagg ctacatcctt ggattattgg
     9241 cagcttatgc tggtggcttc gttgctacat tcttcttcgg tattcctaaa gaccgtttag
     9301 aaaaagaaga attagcgact gaaacagcca cagtaaatga agtgcctgaa aaagtagtac
     9361 ctcaaacttc agctgaaagt gtgactatcc tctcatcagt tgctgacgga acagttgttt
     9421 ctttagataa agcaagtgat ccagtttttg cacaaaagat gatgggtgaa ggctactttg
     9481 tagaaccaga aaacggacat atctattctc cagttactgg ggtagtcagc tctgtcttcc
     9541 caacgaaaca cgctattggg atcacaacgc caaatggttt agaaatcttg cttcatatgg
     9601 gaatcaacac agttgactta ggcggtacgc catttgatgt gaaagtaaca gaagggcagc
     9661 aagtgacacc tgatacgctt gtagcagaag ctgacttaga agcgatcaaa gcagcaggca
     9721 aagaaacatc catgatcgtc ttggtaacca atatggatcg tgtaaaaaac tttgtcttgg
     9781 aaaaaacagg taaagcaaaa gcaaaagcac ctgtgatgga tgtcaaagct taatatgata
     9841 gaaacaatag aaacgaaaga agaaactgaa atctattttt cagcttcttc ttttttatta
     9901 tttattgttt tctgctaaaa tctgataaat tcgtgtcaca tcagatggtg ttccccgtaa
     9961 ttcataatct gccaagaaag gaaagccaaa tgtttgtgca tattgtttgg ctgttagaca
    10021 atactgatta ttgaagtttt tatttccgct accgactaca ccaagacaaa gtttatgatt
    10081 gtcttcatgt tccagatatt cacgcatcgt ttcggtcaag atttctgtat caccgttatc
    10141 taaaccattt ccgccgtcta aataagtagg aacgaaagta aaaaatggtt ctgtttcttt
    10201 cgtaaaatca ctattttcat ggatttcttt taaagtaact tcaggattga caggatcttc
    10261 tgcatgcatt ttttcagcat attctgctag atgtttggca aaggcacgcg tatttcctga
    10321 aatcgatata tataaaatgt tcatgg
//
LOCUS       DAMEEU010000225         7958 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.104, whole genome shotgun sequence.
ACCESSION   DAMEEU010000225 DAMEEU010000000
VERSION     DAMEEU010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7958)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7958)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7958
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.104"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            128..1564
                     /locus_tag="PB779_003032"
     CDS             128..1564
                     /locus_tag="PB779_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HDE0740465.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="PB779_003033"
     CDS             1753..4200
                     /locus_tag="PB779_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HDE0740466.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="PB779_003034"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="PB779_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HDE0740467.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="PB779_003035"
     CDS             complement(5690..6793)
                     /locus_tag="PB779_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HDE0740468.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7345..7893
                     /gene="aac(6')"
                     /locus_tag="PB779_003036"
     CDS             7345..7893
                     /gene="aac(6')"
                     /locus_tag="PB779_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HDE0740469.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2665 a         1359 c         1729 g         2205 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacataa ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taatttttta ttttataagt aagataaata atgaaagaat agagatactg
     7261 attggtagct aaagattttt gagcgagaac atttcgtttt ttcaaaagga ctgttagaat
     7321 aagcaagaac aagggggaag acgtatgata atcagtgaat ttgaccgtaa taatccagta
     7381 ttgaaagatc agctttctga tttactgaga ctgacttggc cggaagaata tggagacagc
     7441 tcggcagaag aagtagaaga aatgatgaat ccagaacgaa tcgcggtagc agcggtagac
     7501 caagatgagt tagtaggatt tattggtgca atccctcaat acggtatcac aggttgggaa
     7561 ttgcatccat tagttgtaga aagctcccga cgaaagaacc aaataggtac tcgattagtc
     7621 aattacttag aaaaagaagt agcttccaga ggaggaatca cgatttattt aggtacggat
     7681 gatttagacc atggaacaac gttaagtcaa acggacctgt atgagcatac atttgataaa
     7741 gtggcttcca tccagaacct tcgtgaacat ccgtatgaat tctatgaaaa attaggttat
     7801 aaaatcgtag gtgtcttacc aaatgcaaat ggctgggaca aaccggatat ttggatggca
     7861 aaaacgatta ttcctcgacc aaattctcaa taataaaaag aggttgtgac agaagtaatc
     7921 agcttcaaga aataagaagg aatttacgaa aattactt
//
LOCUS       DAMEEU010000226         7042 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.109, whole genome shotgun sequence.
ACCESSION   DAMEEU010000226 DAMEEU010000000
VERSION     DAMEEU010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 7042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7042
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.109"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            71..1309
                     /locus_tag="PB779_003037"
     CDS             71..1309
                     /locus_tag="PB779_003037"
                     /inference="COORDINATES: protein motif:HMM:NF017760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0740470.1"
                     /translation="MQAEKKLFNRDFILVVIGQIISLFGNAILRFALPYYLLKETGSS
                     ALFGIATACSFLPMVILSLVGGIIADRTNKRNIMVILDFVTAIIILVFYLSLGKIPII
                     PLFIVALMLLYGISGAYQPAVQASIPLLVSSDKLTVGNAIINQVNTLANFIGPAISGV
                     VFQFYGINPILIVSIICFTFSAIMEIFIHIPHQKRPREVGVIAVAKNDLKDSYTFLKK
                     EKPIFISVIFLVCIFNLVLSAVLIVGLPILISEVLKMPDTLYGFSQSALSLGGLCGGI
                     LTALVASKLKLKNLYTLLLICSVSVLLMGISLFLELPAIVSYWVVTVMCFVAMGVSTM
                     FVVQIYTLVQTQTPPQLVGKIMATLVAVAMCGQPIGQMVYGILFDVFIQETWVVMFVA
                     SIASIMISIYSKRIFQKLEI"
     gene            1536..1955
                     /locus_tag="PB779_003038"
     CDS             1536..1955
                     /locus_tag="PB779_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009588541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HDE0740471.1"
                     /translation="MRTSSFEHIVRLQFNSLMLIVIKNKVKSRNRQLARHSKREVLFC
                     EIAETKQVERGTIDTCFYDCVSFKVLHFTIYVSDETLGTVLHRLSEKQRSAILLRYFQ
                     GMNDREISELYHVSRSAICSRRTRGLRKLKMLLSERK"
     gene            1960..2199
                     /locus_tag="PB779_003039"
     CDS             1960..2199
                     /locus_tag="PB779_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004609551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HDE0740472.1"
                     /translation="MSKDYGYPSFELICKASSGDEMAVKEILKFYDGYISKLCLRPFY
                     HSESGKIIMQVDEELKGEIHTDMMKAILKFEIGVK"
     gene            complement(2424..3347)
                     /locus_tag="PB779_003040"
     CDS             complement(2424..3347)
                     /locus_tag="PB779_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HDE0740473.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            complement(3379..4143)
                     /gene="map"
                     /locus_tag="PB779_003041"
     CDS             complement(3379..4143)
                     /gene="map"
                     /locus_tag="PB779_003041"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HDE0740474.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            4301..4741
                     /locus_tag="PB779_003042"
     CDS             4301..4741
                     /locus_tag="PB779_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HDE0740475.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            complement(4919..5488)
                     /locus_tag="PB779_003043"
     CDS             complement(4919..5488)
                     /locus_tag="PB779_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HDE0740476.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            5743..6975
                     /locus_tag="PB779_003044"
     CDS             5743..6975
                     /locus_tag="PB779_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HDE0740477.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
BASE COUNT         2225 a         1243 c         1310 g         2264 t
ORIGIN      
        1 aaaagagcag tttatttaaa ccattatata aaccgacggt ctgtttgatt aaataaaaag
       61 gagagatttt atgcaagcag aaaaaaaact ttttaatcgt gattttatac ttgttgttat
      121 aggacagata atttctttat ttggaaacgc tatcctacga tttgcattac cgtactattt
      181 gttaaaagaa actggttcat cagctttgtt tggtattgct acagcctgct cttttttacc
      241 tatggttatt ttgtcgctgg taggtggtat tattgctgac aggacaaata aaagaaacat
      301 tatggtcata ctagattttg taacagcaat cataatttta gtattttatt tgtcattggg
      361 aaaaattcct atcatacctt tgtttattgt tgctttgatg ttactttatg gtatttctgg
      421 tgcatatcaa ccagcggtac aagcaagtat tcctctattg gtatcatcag ataaacttac
      481 cgtcggtaat gctataataa atcaagtaaa tactttagca aactttatcg gaccagctat
      541 aagcggagta gtttttcaat tttatggtat caatcccatt ttaattgtta gtattatatg
      601 ttttactttt tcagccatta tggaaatttt tatccatatt ccacaccaaa aaagacctcg
      661 tgaagtaggt gtaattgcag ttgctaaaaa cgatttaaaa gatagttata cctttttgaa
      721 aaaggagaaa cccattttta tatccgtaat ctttttggtt tgcattttca atttggtttt
      781 aagtgctgtt ttaattgttg gtctgcctat cttaatttct gaagttttaa aaatgccaga
      841 tacactatat ggtttttcac aatcagcatt atcattaggt ggtttatgtg gtggtatttt
      901 aacagctctt gttgcttcaa agttaaaact aaaaaacctt tataccttgt tacttatttg
      961 ttctgtttct gttttactta tgggaatttc gctattttta gaattgcctg caatagtttc
     1021 ctactgggta gttacagtga tgtgctttgt ggctatgggt gtatctacta tgtttgttgt
     1081 tcaaatttac actcttgttc agacacaaac accaccgcaa ttagtaggaa agataatggc
     1141 tacgctggta gcagttgcta tgtgcggtca acctattgga caaatggttt acggtatttt
     1201 attcgatgta tttatacaag aaacatgggt tgttatgttt gtagcttcta ttgcttcaat
     1261 catgatttca atatattcaa aaagaatttt tcaaaagtta gagatataat acaaggggtt
     1321 aaatagtatg ttaggctaaa aacaatatat aaaagaaaat ttgaaatctg ctaaaaggat
     1381 agtgttataa aagaaagagt aatattgcag tatttaaggc tcgcacaaat atatgttttg
     1441 tgtgggcttt tttcttacca tttttctgta tttctaaagg gtataaacgg tattccgttt
     1501 atatatttca gcattagcag aaagggggtg agattatgag gacatcttct ttcgagcata
     1561 tcgtcagatt acagttcaat tctttaatgc tgattgtcat taagaacaaa gtgaaaagtc
     1621 gaaacagaca gcttgcaaga cattctaaac gtgaagtatt gttttgtgaa atagccgaaa
     1681 cgaaacaagt tgaacgtgga acgattgata cctgttttta tgattgtgta tcatttaaag
     1741 tcttgcactt tacaatttat gtatctgatg aaacacttgg tacagtttta catagactgt
     1801 cagaaaaaca gcgtagtgcg attttattac gttattttca aggaatgaac gacagagaaa
     1861 tttcagaact gtaccatgta tcacgttctg ctatttgcag tagaagaact agaggactaa
     1921 ggaagttaaa aatgcttttg agcgaaagga agtaaagaaa tgagtaaaga ttatggctat
     1981 ccctcttttg aattgatttg caaagcgtca agcggagatg aaatggcagt taaagagatt
     2041 ttgaagtttt atgacggtta tatttctaaa ttatgcttgc gtccttttta ccactctgaa
     2101 agtggtaaaa tcattatgca ggttgatgaa gaactaaaag gagaaattca tacagacatg
     2161 atgaaagcaa tattgaaatt tgaaatcgga gtgaagtaat caactgtata aaaaaatcgg
     2221 gagatacaca gtttcgtgct atctccctta gtagttttac ggtcatatca aggctcattc
     2281 aatcgtggta aattcgtggt aagatgagtg tttttctata cttcaaaatg cttgaatgta
     2341 tagtgtttat gcggataatt gaaaattaga tataaaattt caaataaatt actgatataa
     2401 atttacaata agaactcttg tttctacttt tttttatgag aaaatttagt tttcaattta
     2461 ttgaaccatt ttcggcttgg atctcgacgt tttttgattt gatgacccgt cacgtattct
     2521 tgaacaactg cattgatgat tccgcccaaa atgatgatcg tagcagcaaa attaagccaa
     2581 agcatgagta caataaaact tcctatgatc tgataaccgc tgatcctcgt tgcaaaatac
     2641 ctagcataga tactaaacac ttgtgataac agcatccagc cgacagtagc gaagatcgtg
     2701 cccggaatga tcgtcttcaa cttcaactga gcattaggga caattaaata aatcaagaac
     2761 atgatgacaa ataaagctac caatgtgatt ggccacttca aagtttggaa ctgatcgata
     2821 aagttcacgg gtatttgtac gattggctga atagcatcca aaatcagctg tcccaaccca
     2881 agaacgatag ttaccccact aatagcaatc atgaacaaga caatgacaat tagtgagaag
     2941 aaacggacga tcaaaaaatt ttttctattt tctacgccat acgctttatt catcgcaatt
     3001 tgcaaagcat tgatactttg acttgcagac cataaagccg ctaatgcaga aacggataac
     3061 aagcctcctg aactttgtgt caaaaggtct ttgattgcag gaccgataaa ctggtaaacg
     3121 gtctcaggaa tcacttctcg taaataggtc agtacagtct cttgatcgat gtggagaaac
     3181 ggtaaaatat taccaaaagc aataatcaat ggaaataaag acaagagtaa ataataagca
     3241 acgacgacag aggtcgtact catttctgaa tcagtgatgc gcttttgagt cgtctcaata
     3301 aagcgcatca gattttcatt ttgttttatt ttgttccaaa ctttcatgta cctctcccgt
     3361 acctattgac tggatagatc aataagtgcc ttcttctcct tgtgatgtca aaattcttgg
     3421 accatcttta gtaatagcca atgtatgttc atattggcaa gaaagtccgc cgtctcttgt
     3481 atacgcagtc cagccgttag gatccatttt cattttccaa gttccggtat taaccatagg
     3541 ttcgatcgtg ataaccatgc cttctttcaa ccgcaaccct tttccagctt ctccgtaatg
     3601 aggaactgct ggttcttcat gaatcgtagg accaacgcca tgaccaataa aatcacgaac
     3661 gatcgctaga ttttcgcctt ctacataagt ttggatagca tgaccgatgt caccaatccg
     3721 attccctact tgtgcttgct caataccgat gtacaaagct ttcttcgtta cttccatcaa
     3781 tcggtcgatc tcaggtgtag attctccaac tacataggcc caacaagaat cagaaatgcc
     3841 gcctttcaaa tcgatacaca tatcgacttt taccaaatca ccgtttttca aaggcttttt
     3901 acgagggaat ccatgacaaa tttcatcatt tatactgata caagtcgcat attcataccc
     3961 ttcaaagcca atttgcgcag caattccgcc atgactctcg atatagtttc tgacaaatac
     4021 ctcaatatcc caacttgtga ttcctggttt tataaaatca cgcagatttt tatgtacatc
     4081 tgctaataaa gctccagatt ctgccatcat ttcaatttca cgtgctgatt ttaaagtaat
     4141 catattttcg tctccttttt acaaatccct ctcattttaa catagcggca tacatttagc
     4201 caaatgacat tccccaggtg tctctaggtt ttattttctt ttcaatgatg ttttggtata
     4261 attcataatt gttaaataat tataaacgag gaggcacatc atggctttag caaaaatcgt
     4321 atatgctagc atgacaggaa acactgaaga aatcgccgat attgttgcag aagcatttga
     4381 aaatctggat atcgaagtcg aaatcaacga atgtacccaa gtagatgcag atgaattcga
     4441 ggaggcagat atttgcgtag tagctactta tacatacgat gatggcgatc tgcctgatga
     4501 gatcgtagac ttttatgaag acttgcaaga attggatcta ttgggaaaaa tttacggtgt
     4561 ctgcggatct ggtgatactt tttacgatga attctgcaaa tcggtggatg atttcgatgc
     4621 tgcttttgca aaaacaggcg catcaaaagg agccgaaaat gttaaagtgg atctgaatgc
     4681 tgaagaagaa gatatcgaaa atttagaagc tttcgctaaa gaactagtcg caaaaattta
     4741 atatacttgc aataaaagag ccatccagat ttattcaatc tgtatggctc ttttattcat
     4801 tgcattcatg gaagagttct tcgggagtta aaaatgcata cgctgtaaga aaaacgaact
     4861 tttccttatt ttgacacatc tcttgttacc tactgatttg tggaactttt gagtatattc
     4921 aatcgatttc gattggttct ttgaatttca agatagcatc tatactgtct tggatcatct
     4981 tttcaatctg ttcatcagtt ggatggatga tgcttgaaga catcaaagct gcgatcccag
     5041 tagctatgat ccatgtccca ttatacaaag attcgatctg ctcttctgaa agattcacat
     5101 aagctggatc gcgtttcact gtattcacaa agtaagtata agagaaattc tgcatctctt
     5161 ttcctccacc atattcttct aagtacagtg aacgatacaa cttcttctct cttcttgcaa
     5221 aatggatata attaaaagca agatcgataa tcgtattccc tgtatgctca acagtgaaca
     5281 cttcatattg taaatgatca tagatctgct caaaaagagc ttgtctcaag tcatccatat
     5341 ttttaaactc aagataaatc ggttgcgtgg aacaattcat tttgttcgcg atgtttctcg
     5401 cagtaaatcg tgtaaatcca tcggtggcag ctacttcata agcagctgcc aaaatctgtt
     5461 ctctagtaat cgtctttttt cttgccatat tttttaatct ccttaatttt tttataacgc
     5521 ttccaccatt gattaatttc attgtaacat gttttttttg atatgcaaaa ttagtttttg
     5581 attttcttca caagctgaaa tagcaagtag taacatatat catgaaactt aaccttaaaa
     5641 aaataacctc ctttttttat ttaaagcctc attgtttgaa tcataattaa atggtatcat
     5701 gctaatagtt accagaaaaa atggtgagga ggaattttta ttatgttatc tgattttaat
     5761 gaacttctaa aaaaatatgc acgcttaatt gcagaaactg gcgtagccac agaaaaagga
     5821 cacacagttg ttttacagat cagcgtggaa caggcacccc ttgctcgatt gatcacacaa
     5881 gaagcttata aactaggagc cgctgaggtt atcgttcaat ggactgacga ccagatccaa
     5941 agagaatttc ttttacatgc tgcaacggat cgtattgaga atgtaccaca atctaaaatc
     6001 gatcaagcgg atgaatggct tgaaaaagga gcaagcagga tcagcgttgt ttctgccgat
     6061 cccgatgcat ttgctggtgt agatagccat cgagtagcgt cttatcaatc agcgaatggc
     6121 aaagcactaa tgaatttacg caaggcaact caagcaaata aagtcagttg gactgtcgtg
     6181 gctgcggctg gtaaacaatg ggcagcaaaa gtcttcccag aactgccaga agaaaaacaa
     6241 gttgaggcat tatgggatca gattttcaaa acgactcgtg tctatgaaga agaccctgtc
     6301 ttagcatgga agaagcatga tgaaaaatta gcaaaaaaag cagaagaatt gaatcgagaa
     6361 caattttctg cccttcacta tactgctccc ggtacagata tcattatcgg attgcctaaa
     6421 aaccatcttt gggaaggcgc tggaagctat aatgctcgtg gagaaaaatt catggcaaat
     6481 atgccgacgg aagaagtgtt cacagcacct gacagtcatc gagtagatgg ttacatttca
     6541 agtacaaagc cactgagtta tgctggcacc atcatctcgg gtatgaaatt tacttttaaa
     6601 gatggaaaag ttgttgattt ttctgccgaa caaggagaag atgtcttagc aaaactgctt
     6661 gatacagatg aaggtgcgcg tcgtttagga gaagtcgcac ttgtacctga cccttcacct
     6721 atttctcaat ctggcatcat ctttttcaat acattatttg atgaaaacgc atcgaatcac
     6781 ttagcactag gttctgctta tgccttcagt gtgaaaggcg gtacagaaat gtccgatgaa
     6841 gaattagcag aagctggatt gaatagaagt caaacccacg tagatttcat ggtaggatct
     6901 gacaagatgg atatcgacgg aatccgtgaa gatggctcta cagtaccgat tttccgaaat
     6961 ggcgattggg cttgagtata ctttcgcaca catgcaaaaa ataatggctc tttgtcaata
     7021 aggactgatg agttgtgcaa aa
//
LOCUS       DAMEEU010000227         4998 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.124, whole genome shotgun sequence.
ACCESSION   DAMEEU010000227 DAMEEU010000000
VERSION     DAMEEU010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4998
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.124"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            40..594
                     /locus_tag="PB779_003045"
     CDS             40..594
                     /locus_tag="PB779_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HDE0740478.1"
                     /translation="MPHEEMLEMIKEATTAPSSVNMQPWRFVVAESEEAKEILRPLIR
                     FNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAYESGKMPKEVRDQQLAAIIPYYKSFS
                     REEMNDVVKVDSSLAAMQFMLVARDHGYETNPIGGVEADQLAEAFGLDKDRYVPVIIL
                     SIGKAVEEGYESVRLAPEKITTFE"
     gene            948..2426
                     /gene="msr(C)"
                     /locus_tag="PB779_003046"
     CDS             948..2426
                     /gene="msr(C)"
                     /locus_tag="PB779_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
                     /protein_id="HDE0740479.1"
                     /translation="MENLAVNITNLQVSFGNQLELSIDSLRVYQQDRIGIIGENGVGK
                     STLLKLIAGELFPDHGKIQTEITFNYLPQLTYLAEAKDLNLELASHFQLRLEETSERK
                     WSGGEERKIELIRLLSSYEQGMLLDEPTTHLDRKSIDRLIEELRYYYGTLVFVSHDRY
                     FLDELASKIWEVKDGEIREFSGNYSAYLTQKELEKKTQLREAESIMKEKKRLEKSIQE
                     KKKQAEKLEKVSSKKKKQQIRPDRLSSSKQKDSVQKAIQKNAKTLERRLQKIGETTKP
                     QQMKQIRFPVPKSLELHSRYPIMGQNVQLERSGRTLLVNGDFQFSLGKKIAIVGENGS
                     GKTTLLEHIRKQGEGILLSPKVSFQVYQQKGYQMTSEESIIRFVMRQTEFSESLVRSL
                     LNHLGFAQETLTKPLCTLSGGEATRLTIALLFTKPSNVLLLDEPTNFIDMATIEALEK
                     LMQIYPGTILFTSHDSYFVERTADEVYEIKGQKIKKVLTRNF"
     gene            2473..2919
                     /locus_tag="PB779_003047"
     CDS             2473..2919
                     /locus_tag="PB779_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HDE0740480.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(3118..3633)
                     /locus_tag="PB779_003048"
     CDS             complement(3118..3633)
                     /locus_tag="PB779_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HDE0740481.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            3750..4952
                     /locus_tag="PB779_003049"
     CDS             3750..4952
                     /locus_tag="PB779_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HDE0740482.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         1520 a          841 c         1088 g         1549 t
ORIGIN      
        1 ggtagaagat ccgttcgcgt atatgatgaa acatacaaaa tcccacacga agaaatgctg
       61 gaaatgatca aagaagcgac gactgcacct tcttctgtca atatgcaacc atggcgcttt
      121 gtggtcgctg aaagcgagga agcaaaagaa atcttgcgtc ctttgatccg tttcaatacg
      181 agacaaaatg atacttcttc tgcaatggtc atgatttttg gcgatatgca atgttacgaa
      241 tatggcgaag aaatctataa ccaagcttac gaatcaggga agatgccaaa agaagtcaga
      301 gatcaacaat tagctgcgat cattccttat tacaagagtt tttcaagaga agaaatgaac
      361 gatgtagtca aagtcgattc tagcttagcg gctatgcaat tcatgttagt tgcgcgtgat
      421 catggctatg aaacaaatcc aattggtgga gtcgaagcag atcagttggc agaggcattt
      481 ggtttggata aagaccgtta tgttccagtt attattttat caataggaaa agcggtagaa
      541 gaaggttacg agtctgttcg tttagcacca gaaaagatca ctacgttcga ataaaaggtt
      601 ttcagttact attcagtagc tattgctttt tttgaatcgt gtgtggtaac ctaataaaaa
      661 aggaggtcgg aaaaatgact gcatcgatga aattacgttt cgaacttttg aataacaact
      721 aaataaattc aaaagacatg tataaacaac aatttcatgg atggagtatg tccatttttt
      781 cgaacgacag tagaataggt gaaagctatg acagatttgg tgatttagtc atagttattt
      841 cgttcagagt aggaaaagat gtgatgcagt ttttttgcaa acagattttt ctgctctttt
      901 ttagtatcga taattgttgt tttacatgaa ataggagtgt aaaacatatg gaaaatttag
      961 cagtaaatat aacaaatcta caagtcagct ttggcaacca gctagaacta tctattgatt
     1021 ctcttcgtgt ctatcagcaa gatcgtatag ggatcatagg agaaaatggt gtcggtaaat
     1081 cgactttgct caaactaata gccggtgaac tttttcccga tcatgggaaa atccaaacag
     1141 agatcacctt caactacctg cctcaattaa cctatctcgc tgaagcaaag gacctaaatt
     1201 tggaattagc cagtcatttc cagttaagac tggaagaaac ttcagagcgg aaatggagcg
     1261 gaggggaaga acgaaagatc gagttgatac gtcttctttc ttcttatgaa caagggatgc
     1321 ttctagacga gccaacaacc catctagata gaaaaagtat tgatcgactg attgaagagc
     1381 ttcgttatta ttatggtacg ctggtttttg ttagtcatga tcgctatttt ctagatgagc
     1441 tagcatcgaa aatctgggaa gtaaaagacg gagaaatccg agagttttcg gggaattata
     1501 gtgcctatct cactcaaaag gaattggaga aaaagactca gctacgagaa gcagagtcga
     1561 tcatgaaaga gaaaaaacga ttggaaaaat cgatccaaga aaagaaaaaa caagcggaaa
     1621 agttggaaaa agtgtccagt aaaaagaaaa agcaacaaat cagaccggat cggttgtctt
     1681 cctctaaaca aaaagacagt gtacaaaaag ccatccaaaa gaatgcgaaa acattagaga
     1741 gaagactcca aaaaatagga gaaacaacca agccgcagca gatgaaacaa atccgttttc
     1801 cagtaccaaa atctcttgaa ctccacagcc gctatcccat catgggacaa aatgtccaat
     1861 tggaaagaag tgggagaaca ttactggtaa atggtgattt tcagttttct ttaggtaaaa
     1921 aaatcgcgat tgtcggtgaa aatggttcag gtaagacaac cttattagaa catatccgca
     1981 aacaaggaga aggaatcctt ctctctccga aagtaagctt tcaagtatat cagcaaaagg
     2041 gttatcaaat gacatctgaa gaatccatca ttcgttttgt catgagacaa acagagtttt
     2101 cagaatcgct tgtccgtagt ttgctgaatc acttagggtt tgctcaggaa actttgacga
     2161 aaccgttatg tacattaagt gggggagaag cgacccgtct gacgattgct ttgcttttta
     2221 ctaagccaag taatgtgttg ctgttagatg aaccgactaa ttttattgat atggcaacga
     2281 tcgaagcttt agagaagcta atgcaaatat atccgggaac gattttgttt acttctcatg
     2341 attcttactt tgtcgagcgt acggctgatg aagtttatga aataaaaggg cagaaaataa
     2401 aaaaagtact tacgagaaat ttttaaatgt gctacgatga ttttcgtgac aaatttaaag
     2461 gagtggtaca gattgcctac aaataaaaaa gaaggaataa tttttacaac aatgatgtgt
     2521 tttttgatgg tcttggggat gagcgcgtat aatttatggc tgcatcaaga tcttcattta
     2581 tcaagtttgt tgattggtct agtgcctgga ttcgtggtgg ctttcatttt ggatgtcttc
     2641 atcatcggtg tgctggcgaa aaaaattgcc tttaaactac cagtaaatcc agaaagcaag
     2701 gtccaaatga tcttaactat ttcatgcttg atggttttag gaatggtgac atgtatgtct
     2761 ttattcggtg tgatcatgga acaaggaata cctgatcaat tattctctgc ttatatgaat
     2821 gcttggaaaa tgaatgtgat tgccgcttta ccgttgcagt tgatcatcgt tggcccgctt
     2881 tcaagaagtg tgctaaaagc aattcaaagt aatgaatgat ggaacactgt tatttgaaaa
     2941 aaggccttgg catgcttttt gtcatagtct cttgaatgca gttctagaaa aatagtgatc
     3001 cgaacgatag gttttggcct gtcgttcgga tcgctttttc ttttccaact gtattgctct
     3061 tttattgaag ataatttgct cttcaataga tatttctaga aaggttctgt ttatccctta
     3121 ctcaaaaaac tgctgcattt gttctcttac ttgctgacac cattggagtt cctgctgaca
     3181 aagcataatt ctgcgctgga tcacaacata acgtccaaat tcttgtttct tgtctagcga
     3241 gaggtcattc aatttttttt gatttttttg catgattttg ttcagctgtt gttctctagt
     3301 gaatagcagt ccagtagctg ttgttttatc gagcgtcgaa aaagcataga tttttgctag
     3361 aaattcatct ttttgcgtag gagcgggagt ttcctctttg atccattcct ctacaagagc
     3421 acgtccttca tcagtcaagt ggtagatctt tttttgagag tgctcgtctt tgtccaaaac
     3481 ggtcacataa ccctgctggt ctaacttggc aagcgttgta tagatctgac tgtgatgggc
     3541 ttcccaaaaa attgtgatca gctgcttcaa ttcataccca gaacgtggtt tggataaaag
     3601 cacgcataat aatatatagg ctaaagtatt cataaaaatc ctacctctcg tcttattttc
     3661 tttattatat cacagtaaag tttccacgtt ttacatgtgc atatttacat gtaaaataaa
     3721 tcatgtatga tgctaataga gagaaaggga tggaaatatt ggagaatcaa atagatatac
     3781 aagaacaaac aaatgaagaa acaaagggga aaagttcagc gctagttgta gcagctacct
     3841 gtatgatcgc ttttatggga gtgggtctag tagacccaat cttaaaaacg attgctgcac
     3901 agttaaacgc tacgccagct gaaacgaccc tgttatttac tagttacatg ttagtcactg
     3961 gtgtggtgat gctatttaca ggtttcttat ctagtcggat cggtttgaaa aaaacattga
     4021 tgacaggatt gtttatcatc gttgtattcg ctggtcttgg cggattatct gggaatatcg
     4081 gaatgctgat tgggttacgt gccggctggg gtgtcgggaa tgctttattt gtctctactg
     4141 ctttagcaac gatcgtcagt attttagttg gtaacacaga aaaagcaatc atgatgtatg
     4201 aagcagcact tggctgcgga atggctgttg gccctctagt cggtggggtc ttgggcagtg
     4261 gttcatggcg ttatccattt tttggggtag catttttgat gttttgcggt tttatagccc
     4321 tagcggtact tttacctgaa actgagaaac caaagagaaa agtaggcctt tgggaaggtg
     4381 tcaaagcgtt aagcaatcat aaacttcgtt cagttggact aatcgcattg ttatataatt
     4441 tcggattctt tactttactt gcgtatgcgc catttttatt gattggctat tctgaattag
     4501 aagtcggttt tgtatttttt ggctggggtg tgcttctggc tattgcttcg attttcgttg
     4561 caccggctct tgagcggaag tttacgactt atcggacaat tttagcagca tttgtcttat
     4621 tcattatttg tttgctgtta ttaggagctg gaacttctat gccagtcctt gtaccgatca
     4681 gcattgtgtt agcaggattt ttccaaggaa ttatcaatac actgttgacg acgattgcta
     4741 tggaaatacc aggtctgcaa cgaaacgttg cttcgtccag ctatagtttt gtccgctttt
     4801 tcggtggagc tttagcacca tttattgcag gtgtgattgg tgaacatatt ggtgaaagct
     4861 atgcgtttta ttttgcaggt gccattgttc ttatcagtgt atgttgtatc atttatcacc
     4921 gtaattattt tgctacaaat gaagaagaat aagaaatcag aggttgtgaa aaagctgtcc
     4981 tgcatcaagt cataagaa
//
LOCUS       DAMEEU010000228         4315 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.134, whole genome shotgun sequence.
ACCESSION   DAMEEU010000228 DAMEEU010000000
VERSION     DAMEEU010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 4315)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4315)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4315
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.134"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            155..652
                     /gene="dfrG"
                     /locus_tag="PB779_003050"
     CDS             155..652
                     /gene="dfrG"
                     /locus_tag="PB779_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000868795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrG"
                     /protein_id="HDE0740483.1"
                     /translation="MKVSLIAAMDKNRVIGKENDIPWRIPKDWEYVKNTTKGHPIILG
                     RKNLESIGRALPDRRNIILTRDKGFTFNGCEIVHSIEDVFELCKNEEEIFIFGGEQIY
                     NLFFPYVEKMYITKIHHEFEGDTFFPEVNYEEWNEVFAQKGIKNDKNPYNYYFHVYER
                     KNLLS"
     gene            complement(724..2676)
                     /locus_tag="PB779_003051"
     CDS             complement(724..2676)
                     /locus_tag="PB779_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017431446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insertion element protein"
                     /protein_id="HDE0740484.1"
                     /translation="MTKLKRLATKEDEIVDVKIPISNEELKDRAKQYDLLTPKRFATR
                     YNKMLFLPTSFKWNGSEYPIQYNYCINPFCCNFGKEQHKFKDVKGKPSRYKMTGSSKD
                     KGHKGMYCNDNPIGRGVSQNCTVTPLSNWSVVEEIKRLIEINSIQDVEPDYQFHKEGC
                     SEEESTPFNEPKQFYKRGKSRGKSQRYQCKACKKFTNVLPKREETTTYHQQKNTILPM
                     FAKMVVGRVSVSRTCDILGIGVGTYYHKLEWLYRRCLEFLERYETQPLQTKKFNEMWL
                     NTDKMHYYLNNVRKKGQGSKKYTGFEDLNMQTYIVVSAEVLSRYVFRSDVAYDWNISM
                     DELNEDTRKFKEDHLNTFSRKNDRLDWSYYPQEPSANDSENRNAYLHELGKITNRSRF
                     VDGLNVDAPYTTTAHYWLIKQMVNADEWRMISDDDFSIRNAFYRVFTKELRLSDAHHF
                     ICQVNKTKSRKQCLKEFGQAKAELLDWGDIRGFKTKFLRTLASHYLTELLTSHQFHEE
                     AISKDGERYRKYADNPIKHPLATKDKGFYSVDCRTDLSALEPNEIAKMLLNVNDHSTN
                     SFIQQIRRYISSLERPLTTARGDKKSYIYANFNPKYAQFAITILRTYYNFCRPFKSAD
                     KKVLTPAQRLGITDKQFDWKDIIYFK"
     gene            complement(2683..2919)
                     /locus_tag="PB779_003052"
     CDS             complement(2683..2919)
                     /locus_tag="PB779_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001159903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740485.1"
                     /translation="MQFLEPKNKNAKSVDWEISEQVRVIVKQYAEYAERTESEAVDEF
                     LLNILDDKKFIEWIANKRSNKRIVEKMGIKDRVG"
     gene            3321..3611
                     /locus_tag="PB779_003053"
     CDS             3321..3611
                     /locus_tag="PB779_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HDE0740486.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
BASE COUNT         1357 a          730 c          752 g         1476 t
ORIGIN      
        1 tggccttttt acttttacac aattatacgg actttatcta atataactta tagaaaaaat
       61 tgcttattca actaacgggc aggataatga gaaaaggttt tttgatagaa ataagaaatt
      121 agatggtaaa ttagttaaaa aggctgtgtt ataaatgaaa gtttctttga ttgctgcgat
      181 ggataagaat agagtgattg gcaaagagaa tgacattcct tggaggattc ccaaggactg
      241 ggaatatgtt aaaaatacta caaagggaca tccgataata ttaggtagga agaaccttga
      301 atcaatcgga agagccttac ctgacagaag aaatattatt ctgacgagag ataaggggtt
      361 tacctttaat ggttgtgaaa ttgttcattc aatagaagat gtttttgagt tatgtaaaaa
      421 cgaagaagaa atttttattt tcggaggaga acagatttat aatttgtttt tcccttatgt
      481 tgagaaaatg tacatcacaa aaatacatca tgaattcgaa ggagatactt tttttccaga
      541 agtgaattat gaggaatgga atgaggtatt tgcccaaaaa gggataaaga atgataaaaa
      601 tccgtataac tactattttc atgtatatga aagaaaaaac ttattgagtt aacgggtgcg
      661 ttaattgaag aagaacagta aagataaagc acaagagctt gggattactc caagctcttt
      721 ttgtcatttg aaataaatta tatctttcca atcaaattgt ttatctgtaa tccctaatct
      781 ttgagcaggt gtcaaaacct ttttatccgc tgatttaaaa gggcgacaaa agttgtagta
      841 agttcttaga attgtaatcg caaattgagc atacttcgga ttgaagttag cgtaaatata
      901 gctcttctta tcaccacgag ctgttgttaa tggtctttca agagatgata tataacgtct
      961 tatctgttga ataaagctat tggtcgaatg gtcattaaca tttaatagca tctttgcgat
     1021 ttcgtttggt tccagagcag ataaatccgt tctacaatca actgaataaa atcctttatc
     1081 cttagtggct aatggatgtt tgatagggtt atcggcatat ttgcgatatc tttctccatc
     1141 tttactaata gcctcttcgt ggaattgatg acttgttagt aattcagtta gataatgaga
     1201 tgccaaagtc cgtagaaact ttgttttgaa tcctctgata tctccccaat cgagcagttc
     1261 tgcttttgct tgtccgaatt cttttaagca ttgttttctg cttttcgtct tgttaacttg
     1321 gcaaataaaa tgatgtgcat cgctcaacct taattctttc gtgaatactc tataaaaggc
     1381 gtttctaata gagaagtcat catcactaat cattcgccat tcgtcggcat taaccatttg
     1441 tttaattaac caatagtgag cagttgtagt ataaggagca tcaacattta aaccatcgac
     1501 aaatctactc ctattagtaa ttttccctaa ttcgtgaaga taagcattcc tattttcgct
     1561 atcgttagcg gatggttctt gtggataata agaccaatct aacctatcat ttttacgact
     1621 aaaagtattg agatggtctt ctttgaattt tcttgtatct tcatttaatt catccattga
     1681 aatattccaa tcataggcaa catcagaacg gaacacatat cttgataaga cctcagcaga
     1741 tacaactata tacgtttgca tattaaggtc ttcaaacccc gtatatttct ttgaaccttg
     1801 tcctttctta cggacgttat ttaggtagta gtgcatcttg tccgtattaa gccacatctc
     1861 gttaaatttc tttgtttgaa ggggttgtgt ctcatatcgt tctaaaaact ccaaacaacg
     1921 cctatacagc cactccagct tatgatagta ggttccaact ccaattccta aaatatcaca
     1981 agtacgactg actgaaaccc ttccaacaac catcttagcg aacattggaa gaatggtgtt
     2041 cttttgttgg tgataagtag tggtttcttc tctttttggt agaacattag tgaacttctt
     2101 acacgcctta cattgatagc gttgagattt gcccctactt ttcccccttt tgtaaaattg
     2161 cttcggctca ttgaatgggg ttgattcttc ttccgagcag ccttctttat gaaattgata
     2221 atctggctca acatcttgga tgctattgat ttctataagg cgtttaattt cttcaacaac
     2281 agaccaatta gataaagggg ttactgtaca gttttgcgat acacctctgc caataggatt
     2341 gtcattgcag tacatacctt tatgaccttt atctttggaa ctaccagtca ttttatatcg
     2401 acttggtttc ccttttacat ctttgaattt gtgctgttct ttcccaaaat tacaacaaaa
     2461 cggattgatg cagtaattat attgaatggg atattcagaa ccgttccatt taaaagacgt
     2521 tggcaagaac aacattttgt tataccttgt tgcaaatcgt tttggagtta ataaatcata
     2581 ttgtttagcc ctatctttta attcttcgtt tgaaatcgga attttaacat ctacaatttc
     2641 atcttccttc gtggctaatc ttttaagctt ggtcattgtc tatcaaccca ctctatcttt
     2701 gatacccatt ttttcaacaa tccgcttatt acttcgcttg ttggcaatcc attcaataaa
     2761 cttcttatcg tctaaaatgt tcaataagaa ttcatccact gcttcgcttt cagtacgctc
     2821 tgcatattca gcgtattgct taactatcac ccttacttgc tctgatattt cccaatccac
     2881 agacttagcg ttcttatttt ttggctcaag aaattgcata ggaaaatgca cccctttttg
     2941 cttagtaaat tgtaaccatt ttaacacacc aatttgcatt cctacaataa ttatttcacg
     3001 ttcgcatttt tatatacatt ttaacttaca ttttgtggtg taaattaaca acaaacgttg
     3061 atttaacaat aaaaaacgag tatcaaattc agttgcaatt tgatactcat ttaggtttac
     3121 attttcactt tttgtactcc aaaactgaac tacttaaatc tatactgctg cctctttttt
     3181 ttagtacatg tccttcatct tcgcaggaag tgccaatatg attttaagaa aggtaataga
     3241 caaaaagtca aaaagataaa acagagtttc ttctttacaa agggaatgta tgttcgtata
     3301 atggtattga ggtgaaggtt atggagaaaa aatatggaac agtagataag atccgtactt
     3361 tgcaagttag tgccagaccg ttgatccgtt tcagtttaaa tggggtcaat tgtttgattg
     3421 cttcccatag tttgaacttc ctagctgaag tagacgaagg gatgaagtta gtcgttacag
     3481 gttattataa taatagaaag caatttgttg tgagatccta tcatgtgtta gggaaaccca
     3541 aaattgtggt agaatatgag aaaagtctat acccaagaaa aaaggtccga caagatgaaa
     3601 gaataaacta gaaaacaagc ggctgagaca aaaatgtcct agccgcttgt tttggaaaga
     3661 tggatgcaga cgatgggatt tgaacccaca cgagcatacg ctcacaagaa cctcaatcta
     3721 tatataacta catgtattta agtatttgtg atgaatcact aaactttcca aactcatttg
     3781 agggatattg cttaaagatt gaacagatca attcgaagcc ctattagtat tcgctcaatg
     3841 gggggatcag aggccataaa aagagactag tcattactag tctcaggtag tggaattgta
     3901 ggattttaaa cgttcctgga gagtaccggt atgtaactcg aagaggtgat tatcatagtc
     3961 gtaaaagtaa attgaagaag cctcgccttt cacacgagaa cgtcctggtt cgacagttaa
     4021 acctaacatt tggatttttg agacaaacga atctatatct tgttcgtcaa ttttaaaagc
     4081 aatatgattg tatgtctttg gcagtttatt cgacgaattc tgcattactg caatccatag
     4141 gtccttaact aagaaaaatt tttctggata taatgaaaat ttttttgttg actatcgtag
     4201 atttcttttg catcaaataa ggtatttaac aattaagtat ttaaaagata acttttaagt
     4261 tatctttaag taatgcttaa agctatgtta tactctatta ggaaatataa gaagg
//
LOCUS       DAMEEU010000229         1650 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.172, whole genome shotgun sequence.
ACCESSION   DAMEEU010000229 DAMEEU010000000
VERSION     DAMEEU010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.172"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..285
                     /locus_tag="PB779_003054"
     CDS             <1..285
                     /locus_tag="PB779_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HDE0740487.1"
                     /translation="IIGFAYCYTLLRPDGKTMFYLHSIGMLPNYQDKGYGSKLLSFIK
                     EYSKEIGCSEMFLITDKGNPRACHVYEKLGGKNDYKDEIVYVYDYEKGDK"
     gene            286..>1650
                     /gene="aph(2'')-I"
                     /locus_tag="PB779_003055"
     CDS             286..>1650
                     /gene="aph(2'')-I"
                     /locus_tag="PB779_003055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012655884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APH(2'')-Ia/If/Ih family aminoglycoside
                     O-phosphotransferase"
                     /protein_id="HDE0740488.1"
                     /translation="MNIVENEICIRTLIDDDFPLMLKWLTDERVLEFYDGRDKKYTLE
                     SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHYPKTDEIVYGMDQFI
                     GEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIRAYQKSGFRIIEDLP
                     EHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDSIEIIGSGYDSVAYL
                     VNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEYSYISDELSILGYKE
                     IKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISECTIDNKQNVLEEYIL
                     LRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCNHLLLDGNNRLTGII
                     DFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEKAKEYQDIVEEYYPI
                     ETIVY"
BASE COUNT          682 a          128 c          283 g          557 t
ORIGIN      
        1 attataggat ttgcatattg ctatacactt ttaagacctg atggaaaaac aatgttttat
       61 ttacactcaa taggaatgtt acctaactat caagacaaag gttatggttc aaaattatta
      121 tcttttatta aggaatattc taaagagatt ggttgttctg aaatgttttt aataactgat
      181 aaaggtaatc ctagagcttg ccatgtatat gaaaaattag gtggtaaaaa tgattataaa
      241 gatgaaatag tatatgtata tgattatgaa aaaggtgata aataaatgaa tatagttgaa
      301 aatgaaatat gtataagaac tttaatagat gatgattttc ctttgatgtt aaaatggtta
      361 actgatgaaa gagtattaga attttatgat ggtagagata aaaaatatac attagaatca
      421 ttaaaaaaac attatacaga gccttgggaa gatgaagttt ttagagtaat tattgaatat
      481 aacaatgttc ctattggata tggacaaata tataaaatgt atgatgagtt atatactgat
      541 tatcattatc caaaaactga tgagatagtc tatggtatgg atcaatttat aggagagcca
      601 aattattgga gtaaaggaat tggtacaaga tatattaaat tgatttttga atttttgaaa
      661 aaagaaagaa atgctaatgc agttatttta gaccctcata aaaataatcc aagagcaata
      721 agggcatacc aaaaatctgg ttttagaatt attgaagatt tgccagaaca tgaattacac
      781 gagggcaaaa aagaagattg ttatttaatg gaatatagat atgatgataa tgccacaaat
      841 gttaaggcaa tgaaatattt aattgagcat tactttgata atttcaaagt agatagtatt
      901 gaaataatcg gtagtggtta tgatagtgtg gcatatttag ttaataatga atacattttt
      961 aaaacaaaat ttagtactaa taagaaaaaa ggttatgcaa aagaaaaagc aatatataat
     1021 tttttaaata caaatttaga aactaatgta aaaattccta atattgaata ttcgtatatt
     1081 agtgatgaat tatctatact aggttataaa gaaattaaag gaactttttt aacaccagaa
     1141 atttattcta ctatgtcaga agaagaacaa aatttgttaa aacgagatat tgccagtttt
     1201 ttaagacaaa tgcacggttt agattataca gatattagtg aatgtactat tgataataaa
     1261 caaaatgtat tagaagagta tatattgttg cgtgaaacta tttataatga tttaactgat
     1321 atagaaaaag attatataga aagttttatg gaaagactaa atgcaacaac agtttttgag
     1381 ggtaaaaagt gtttatgcca taatgatttt agttgtaatc atctattgtt agatggcaat
     1441 aatagattaa ctggaataat tgattttgga gattctggaa ttatagatga atattgtgat
     1501 tttatatact tacttgaaga tagtgaagaa gaaataggaa caaattttgg agaagatata
     1561 ttaagaatgt atggaaatat agatattgag aaagcaaaag aatatcaaga tatagttgaa
     1621 gaatattatc ctattgaaac tattgtttat
//
LOCUS       DAMEEU010000230         1430 bp    DNA     linear   BCT 09-JAN-2023
DEFINITION  TPA_asm: Enterococcus faecium isolate 302613-17
            SAMEA8238619-rid16559873.guided.177, whole genome shotgun sequence.
ACCESSION   DAMEEU010000230 DAMEEU010000000
VERSION     DAMEEU010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA8238619
            Sequence Read Archive: ERR5462725
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Bacillati; Bacillota; Bacilli; Lactobacillales;
            Enterococcaceae; Enterococcus.
REFERENCE   1  (bases 1 to 1430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (03-JAN-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 03-JAN-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001557432.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001557432.1
            Genome Coverage       :: 159x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 01/03/2023 22:04:37
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,056
            CDSs (total)                      :: 2,993
            Genes (coding)                    :: 2,930
            CDSs (with protein)               :: 2,930
            Genes (RNA)                       :: 63
            rRNAs                             :: 1, 1, 3 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 1, 3 (5S, 16S, 23S)
            tRNAs                             :: 54
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 63
            CDSs (without protein)            :: 63
            Pseudo Genes (ambiguous residues) :: 0 of 63
            Pseudo Genes (frameshifted)       :: 31 of 63
            Pseudo Genes (incomplete)         :: 30 of 63
            Pseudo Genes (internal stop)      :: 11 of 63
            Pseudo Genes (multiple problems)  :: 8 of 63
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA8238619-rid16559873.guided.177"
                     /isolate="302613-17"
                     /isolation_source="clinical sample"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /geo_loc_name="Switzerland"
                     /collection_date="2017-06"
     gene            <1..1311
                     /locus_tag="PB779_003056"
     CDS             <1..1311
                     /locus_tag="PB779_003056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HDE0740489.1"
                     /translation="ESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYH
                     YPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAI
                     RAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVD
                     SIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIE
                     YSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISE
                     CTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSC
                     NHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIE
                     KAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          610 a          111 c          242 g          467 t
ORIGIN      
        1 gaatcattaa aaaaacatta tacagagcct tgggaagatg aagtttttag agtaattatt
       61 gaatataaca atgttcctat tggatatgga caaatatata aaatgtatga tgagttatat
      121 actgattatc attatccaaa aactgatgag atagtctatg gtatggatca atttatagga
      181 gagccaaatt attggagtaa aggaattggt acaagatata ttaaattgat ttttgaattt
      241 ttgaaaaaag aaagaaatgc taatgcagtt attttagacc ctcataaaaa taatccaaga
      301 gcaataaggg cataccaaaa atctggtttt agaattattg aagatttgcc agaacatgaa
      361 ttacacgagg gcaaaaaaga agattgttat ttaatggaat atagatatga tgataatgcc
      421 acaaatgtta aggcaatgaa atatttaatt gagcattact ttgataattt caaagtagat
      481 agtattgaaa taatcggtag tggttatgat agtgtggcat atttagttaa taatgaatac
      541 atttttaaaa caaaatttag tactaataag aaaaaaggtt atgcaaaaga aaaagcaata
      601 tataattttt taaatacaaa tttagaaact aatgtaaaaa ttcctaatat tgaatattcg
      661 tatattagtg atgaattatc tatactaggt tataaagaaa ttaaaggaac ttttttaaca
      721 ccagaaattt attctactat gtcagaagaa gaacaaaatt tgttaaaacg agatattgcc
      781 agttttttaa gacaaatgca cggtttagat tatacagata ttagtgaatg tactattgat
      841 aataaacaaa atgtattaga agagtatata ttgttgcgtg aaactattta taatgattta
      901 actgatatag aaaaagatta tatagaaagt tttatggaaa gactaaatgc aacaacagtt
      961 tttgagggta aaaagtgttt atgccataat gattttagtt gtaatcatct attgttagat
     1021 ggcaataata gattaactgg aataattgat tttggagatt ctggaattat agatgaatat
     1081 tgtgatttta tatacttact tgaagatagt gaagaagaaa taggaacaaa ttttggagaa
     1141 gatatattaa gaatgtatgg aaatatagat attgagaaag caaaagaata tcaagatata
     1201 gttgaagaat attatcctat tgaaactatt gtttatggaa ttaaaaatat taaacaggaa
     1261 tttatcgaaa atggtagaaa agaaatttat aaaaggactt ataaagattg attatataat
     1321 atatgaaaag ctattataaa agacattagt attaaatagt ttaaaaaaat gaaaaataat
     1381 aaaggaagtg agtcaagtcc agactcctgt gtaaaatgct atacaatgtt
//
